Phosphodiesterase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30027661 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE10A (phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]) HSP 1 Score: 364.385 bits (934), Expect = 4.431e-117 Identity = 193/438 (44.06%), Postives = 271/438 (61.87%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLH----MALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L T+P K ++ F D P F++++ G+ + V R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N N H + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD K E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 330 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHF-------DIGP------FENMWPGIFVYMVHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQW 745 HSP 2 Score: 79.7221 bits (195), Expect = 4.431e-117 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 190 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 300
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE10A (phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]) HSP 1 Score: 363.999 bits (933), Expect = 4.543e-117 Identity = 193/438 (44.06%), Postives = 271/438 (61.87%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLH----MALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L T+P K ++ F D P F++++ G+ + V R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N N H + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD K E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 337 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHF-------DIGP------FENMWPGIFVYMVHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQW 752 HSP 2 Score: 79.7221 bits (195), Expect = 4.543e-117 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 197 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 307
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE10A (phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]) HSP 1 Score: 363.999 bits (933), Expect = 4.580e-117 Identity = 193/438 (44.06%), Postives = 271/438 (61.87%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLH----MALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L T+P K ++ F D P F++++ G+ + V R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N N H + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD K E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 347 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHF-------DIGP------FENMWPGIFVYMVHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQW 762 HSP 2 Score: 79.7221 bits (195), Expect = 4.580e-117 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 207 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 317
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE10A (phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]) HSP 1 Score: 364.385 bits (934), Expect = 4.972e-117 Identity = 193/438 (44.06%), Postives = 271/438 (61.87%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLH----MALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L T+P K ++ F D P F++++ G+ + V R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N N H + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD K E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 613 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHF-------DIGP------FENMWPGIFVYMVHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQW 1028 HSP 2 Score: 79.337 bits (194), Expect = 4.972e-117 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 473 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 583
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE10A (phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]) HSP 1 Score: 363.999 bits (933), Expect = 5.019e-117 Identity = 193/438 (44.06%), Postives = 271/438 (61.87%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLH----MALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L T+P K ++ F D P F++++ G+ + V R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N N H + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD K E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 349 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHF-------DIGP------FENMWPGIFVYMVHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQW 764 HSP 2 Score: 79.7221 bits (195), Expect = 5.019e-117 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 209 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 319
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-5 (Probable 3',5'-cyclic phosphodiesterase pde-5 [Source:UniProtKB/Swiss-Prot;Acc:P91119]) HSP 1 Score: 427.172 bits (1097), Expect = 1.134e-136 Identity = 212/437 (48.51%), Postives = 281/437 (64.30%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN--SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TG+ LNI +AY DERFN +D TGY TKTILCMP+ ++ +IGVVQM+NK +G FT +DE F FA YCGLALH +K+Y+KI RS+QKY+VA++VL+YH+ + +E KLK + I L+ + F + +P+Y +YMFK LF L RFD E L+RFVLTV+KNYR+V YHNW H +SVAHAM++ L FT EALAL++ LCHDLDHRGK N ++ S PL+++YSTS ME HHFN T+TILQ+DGHNI LS ++YKK L IKHCILATDLA FF + + + IN +RLL A+ MT CDL + K W++Q V +I EF+ QGD E+ G+ PI +MDR LP+ QVGF+ +C+PCY +++ I P++ + E N K+W LA
Sbjct: 287 TGEGLNIENAYEDERFNADVDSKTGYTTKTILCMPILIRGIVIGVVQMVNKHDGVFTRQDEDAFEIFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNADEVNKLKKIEINNRIVELETIDFNGMRLSELEKPLYAVYMFKTLFADTL-----------------RFDTEDLIRFVLTVRKNYRRVAYHNWAHGWSVAHAMFATLMNSPDAFTKLEALALYVSCLCHDLDHRGKNNAYMKTMSTPLASIYSTSVMERHHFNQTVTILQQDGHNILKSLSSEDYKKTLSLIKHCILATDLALFFSNKAKLNVILDNNTFDINRQEHRLLTQAVMMTGCDLVASAKPWNIQTETVKVIFEEFYDQGDAERLSGKEPIPMMDRQQAHMLPQMQVGFMRGICMPCYDLIARIFPKNDKMRERCEYNAKKWEELA 706 HSP 2 Score: 70.8626 bits (172), Expect = 3.011e-12 Identity = 37/102 (36.27%), Postives = 59/102 (57.84%), Query Frame = 2
Query: 1118 DEEIFNNYCTWAGLAIYYNEINLTNQ-------------KQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
++ I N CTWA YY+E+ Q KQ KL+ F+L+V + +F ++D++I ++M A+ LV A+R SLFL+D + ++YA+IFD G
Sbjct: 154 EKSIVNAVCTWAAATNYYSELYTHKQEGSDGQDIHENIAKQRKLSNFLLDVARSIFHDIVSMDAVIIKVMNFAQKLVDADRASLFLVDSKNAQIYARIFDVG 255
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-2 (Probable 3',5'-cyclic phosphodiesterase pde-2 [Source:UniProtKB/Swiss-Prot;Acc:P30645]) HSP 1 Score: 182.57 bits (462), Expect = 2.846e-47 Identity = 133/447 (29.75%), Postives = 214/447 (47.87%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMP-VKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-----GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTL--YEALALFIGSLCHDLDHRGKTNQFIMQT--SGPLSALYST--STMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN-SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
T +T+NIRD FN ID + ++ P + +IGV+ + NK+NG F+ DE F+ + ++ + + ++I + + + + +EE + ++ P F +N SF P +V + + F+DL L + +R L VL V YR VPYHNW+HAF+V H + L+T R L E L+L I LCHD+DHRG TN F MQ+ PLS LYST S +E HHF TI +LQ++ +I +L +++ ++ I+ ILATD++ ++ I+ + N ++ +R L M L MT DL K++ + I EF+ QGD E +G P+ +MDR +P Q+ FL + +P +++L++++PE + N W L
Sbjct: 238 TMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENG-FSRHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDWRYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRK----------------LSYLVLRVSAGYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISAHLRKQERIKTMISEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQLGVKPLEMMDRTNAY-VPTVQIDFLFKIGVPVFQLLASVVPEGRTTSEAIDANHLCWVAL 666
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-2 (Probable 3',5'-cyclic phosphodiesterase pde-2 [Source:UniProtKB/Swiss-Prot;Acc:P30645]) HSP 1 Score: 182.57 bits (462), Expect = 3.135e-47 Identity = 133/447 (29.75%), Postives = 214/447 (47.87%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMP-VKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-----GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTL--YEALALFIGSLCHDLDHRGKTNQFIMQT--SGPLSALYST--STMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN-SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
T +T+NIRD FN ID + ++ P + +IGV+ + NK+NG F+ DE F+ + ++ + + ++I + + + + +EE + ++ P F +N SF P +V + + F+DL L + +R L VL V YR VPYHNW+HAF+V H + L+T R L E L+L I LCHD+DHRG TN F MQ+ PLS LYST S +E HHF TI +LQ++ +I +L +++ ++ I+ ILATD++ ++ I+ + N ++ +R L M L MT DL K++ + I EF+ QGD E +G P+ +MDR +P Q+ FL + +P +++L++++PE + N W L
Sbjct: 235 TMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNKENG-FSRHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDWRYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRK----------------LSYLVLRVSAGYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISAHLRKQERIKTMISEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQLGVKPLEMMDRTNAY-VPTVQIDFLFKIGVPVFQLLASVVPEGRTTSEAIDANHLCWVAL 663
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000]) HSP 1 Score: 107.842 bits (268), Expect = 5.211e-24 Identity = 76/279 (27.24%), Postives = 141/279 (50.54%), Query Frame = 3
Query: 1995 LMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKT--CKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYST-STMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAK----FFEYRQVIEKTPNYTNNKINSNR----------LLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIM-PESGVIIAEAENNLKQWTYLAGLPE 2777
L+ ++L ++ +YR YHN+ HA VA +M+ LL + FT E LA HD+DH G TNQ+++ ++ L+ +Y+ S +E HH + +LQ + ++LS + + + +LATD++K + + ++E NN I ++ ++H+A +++ W+ + IM E+W QGD+EK +G L I M + + + QVGF+ + P Y ++++ P++ I+ + E N ++W Y + +PE
Sbjct: 265 LVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQR------IMEEYWRQGDKEKELG-LEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEEN-REW-YQSRIPE 534
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-4 (Probable 3',5'-cyclic phosphodiesterase pde-4 [Source:UniProtKB/Swiss-Prot;Acc:Q22000]) HSP 1 Score: 107.071 bits (266), Expect = 1.229e-23 Identity = 76/279 (27.24%), Postives = 141/279 (50.54%), Query Frame = 3
Query: 1995 LMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKT--CKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYST-STMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAK----FFEYRQVIEKTPNYTNNKINSNR----------LLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIM-PESGVIIAEAENNLKQWTYLAGLPE 2777
L+ ++L ++ +YR YHN+ HA VA +M+ LL + FT E LA HD+DH G TNQ+++ ++ L+ +Y+ S +E HH + +LQ + ++LS + + + +LATD++K + + ++E NN I ++ ++H+A +++ W+ + IM E+W QGD+EK +G L I M + + + QVGF+ + P Y ++++ P++ I+ + E N ++W Y + +PE
Sbjct: 315 LVTYLLNLEHHYRNNHYHNFIHAADVAQSMHVLLMSPVLTEVFTDLEVLAAIFAGAVHDVDHPGFTNQYLINSNNELAIMYNDESVLEQHHLAVAFKLLQDSNCDFLANLSRKQRLQFRKIVIDMVLATDMSKHMSLLADLKTMVEAKKVAGNNVIVLDKYNDKIQVLQSMIHLADLSNPTKPIELYQQWNQR------IMEEYWRQGDKEKELG-LEISPMCDRGNVTIEKSQVGFIDYIVHPLYETWADLVYPDAQNILDQLEEN-REW-YQSRIPE 584
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde6 (gene:FBgn0038237 transcript:FBtr0300330) HSP 1 Score: 296.204 bits (757), Expect = 1.095e-84 Identity = 177/446 (39.69%), Postives = 253/446 (56.73%), Query Frame = 3
Query: 1461 TGQTLNIRDAYS---DERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNG-EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCK-HRF-TLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQV-IEKTPNYTNN-KINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEK-SIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TGQT+NI D D R+ D I T+ ILCMP+ +K++IGV Q++NK NG FT D S F FA +CGL +H ++MYE + K KVA++ LSYH S ++ EKL + NL +F + + +D VL MF L+ S+ I +D +L R+VL+V+KNYR V YHNW HA +VA M+++LKT K RF T E L L + LCHDLDHRG N F +T PL+ LY+TSTMEHHHF+ + IL +G+NIF LSP++Y+ V+ ++ IL+TDLA +F+ R +E N + + + L + MT CD+ ++ K W++Q + ++ EF+ QGD EK + P+ +MDR+ K ELP+ QVGF+ +CLP YR+L + P + N + W LA
Sbjct: 535 TGQTVNICDVIEWVRDHNQIRAEDEIDS--TQAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQDVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMF---MQCNLV-------SQFQIPYD------VLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLA 962 HSP 2 Score: 78.9518 bits (193), Expect = 1.589e-14 Identity = 38/100 (38.00%), Postives = 64/100 (64.00%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNG--EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDV 1751
T Q +NI++AY D RFN ID+ TGY T ILCMP+ + +IIGV Q++NK NG EF D F + T+CG+ + ++++E ++ ++ ++ +++
Sbjct: 322 TKQMINIKEAYKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKTNGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNL 421 HSP 3 Score: 54.6842 bits (130), Expect = 4.898e-7 Identity = 31/96 (32.29%), Postives = 55/96 (57.29%), Query Frame = 2
Query: 1106 FSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKEL--YAKIFDKGN 1387
F D EIF Y T+ G+ I ++ + ++ + N+ +LN+ + +F + N++ ++ +IM A+ L+K ER S+FL+D D E KI +K N
Sbjct: 380 FDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEASHLEKIIEKPN 475
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde6 (gene:FBgn0038237 transcript:FBtr0345168) HSP 1 Score: 296.204 bits (757), Expect = 1.095e-84 Identity = 177/446 (39.69%), Postives = 253/446 (56.73%), Query Frame = 3
Query: 1461 TGQTLNIRDAYS---DERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNG-EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCK-HRF-TLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQV-IEKTPNYTNN-KINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEK-SIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TGQT+NI D D R+ D I T+ ILCMP+ +K++IGV Q++NK NG FT D S F FA +CGL +H ++MYE + K KVA++ LSYH S ++ EKL + NL +F + + +D VL MF L+ S+ I +D +L R+VL+V+KNYR V YHNW HA +VA M+++LKT K RF T E L L + LCHDLDHRG N F +T PL+ LY+TSTMEHHHF+ + IL +G+NIF LSP++Y+ V+ ++ IL+TDLA +F+ R +E N + + + L + MT CD+ ++ K W++Q + ++ EF+ QGD EK + P+ +MDR+ K ELP+ QVGF+ +CLP YR+L + P + N + W LA
Sbjct: 535 TGQTVNICDVIEWVRDHNQIRAEDEIDS--TQAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQDVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMF---MQCNLV-------SQFQIPYD------VLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLA 962 HSP 2 Score: 78.9518 bits (193), Expect = 1.589e-14 Identity = 38/100 (38.00%), Postives = 64/100 (64.00%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNG--EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDV 1751
T Q +NI++AY D RFN ID+ TGY T ILCMP+ + +IIGV Q++NK NG EF D F + T+CG+ + ++++E ++ ++ ++ +++
Sbjct: 322 TKQMINIKEAYKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKTNGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNL 421 HSP 3 Score: 54.6842 bits (130), Expect = 4.898e-7 Identity = 31/96 (32.29%), Postives = 55/96 (57.29%), Query Frame = 2
Query: 1106 FSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKEL--YAKIFDKGN 1387
F D EIF Y T+ G+ I ++ + ++ + N+ +LN+ + +F + N++ ++ +IM A+ L+K ER S+FL+D D E KI +K N
Sbjct: 380 FDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEASHLEKIIEKPN 475
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0303163) HSP 1 Score: 296.204 bits (757), Expect = 1.265e-84 Identity = 170/447 (38.03%), Postives = 257/447 (57.49%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMK-KEIIGVVQMLNKKNG-EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRF--DAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCK--HRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYR-QVIEKTPNYTNNKINSN-RLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEK-SIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGL 2771
TG+T+N+ +AY D+RF+ S+D + + ++ILCM +K +IIGV+Q++NK N +FT DE+ FA +CG+ +H + MYEK + + K V ++VLSYH +++E +L+ VP + L F +D L MF DL +F +RF D E+L R++L+VKKNYR V YHNW HAF+VA M+++L T + F E LAL IG LCHDLDHRG N F ++ S PL+ LYSTSTMEHHHF+ + IL G+ I ++LS +Y +V+ ++ IL+TDLA +F+ R +E T+ + R L A+SMT CDL ++ K W+++ + ++ EF+ QGD EK + PI +M+R+ + ELP QV F+ +CLP Y + + + ++ +N W LA +
Sbjct: 634 TGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFKFDDIHFEDDDTLKACLRMFLDL------------------DFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYSTSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEPLVEGVRDNRGHWIDLADV 1062 HSP 2 Score: 92.8189 bits (229), Expect = 9.871e-19 Identity = 44/99 (44.44%), Postives = 68/99 (68.69%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVK-MKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDV 1751
+G+ +NI DAY DERFN ID +TGY TK +LCMP+K ++IGV Q++NK NGE F+ DE F+++ +CG+ L +++YEK ++ +V +D+
Sbjct: 452 SGEPVNIPDAYQDERFNCEIDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDL 550
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde6 (gene:FBgn0038237 transcript:FBtr0330048) HSP 1 Score: 296.204 bits (757), Expect = 1.353e-84 Identity = 178/448 (39.73%), Postives = 254/448 (56.70%), Query Frame = 3
Query: 1461 TGQTLNIRDAYS---DERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNG-EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLK---FATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCK-HRF-TLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQV-IEKTPNYTNN-KINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEK-SIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TGQT+NI D D R+ D I T+ ILCMP+ +K++IGV Q++NK NG FT D S F FA +CGL +H ++MYE + K KVA++ LSYH S ++ EKL A + NL +F + + +D VL MF L+ S+ I +D +L R+VL+V+KNYR V YHNW HA +VA M+++LKT K RF T E L L + LCHDLDHRG N F +T PL+ LY+TSTMEHHHF+ + IL +G+NIF LSP++Y+ V+ ++ IL+TDLA +F+ R +E N + + + L + MT CD+ ++ K W++Q + ++ EF+ QGD EK + P+ +MDR+ K ELP+ QVGF+ +CLP YR+L + P + N + W LA
Sbjct: 535 TGQTVNICDVIEWVRDHNQIRAEDEIDS--TQAILCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQDVIAEAESY--NLYSFTFTDFELVDDDTCRAVLRMF---MQCNLV-------SQFQIPYD------VLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLA 962 HSP 2 Score: 78.9518 bits (193), Expect = 1.579e-14 Identity = 38/100 (38.00%), Postives = 64/100 (64.00%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNG--EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDV 1751
T Q +NI++AY D RFN ID+ TGY T ILCMP+ + +IIGV Q++NK NG EF D F + T+CG+ + ++++E ++ ++ ++ +++
Sbjct: 322 TKQMINIKEAYKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKTNGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNL 421 HSP 3 Score: 54.6842 bits (130), Expect = 4.904e-7 Identity = 31/96 (32.29%), Postives = 55/96 (57.29%), Query Frame = 2
Query: 1106 FSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKEL--YAKIFDKGN 1387
F D EIF Y T+ G+ I ++ + ++ + N+ +LN+ + +F + N++ ++ +IM A+ L+K ER S+FL+D D E KI +K N
Sbjct: 380 FDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEASHLEKIIEKPN 475
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0303162) HSP 1 Score: 296.204 bits (757), Expect = 1.787e-84 Identity = 170/447 (38.03%), Postives = 257/447 (57.49%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMK-KEIIGVVQMLNKKNG-EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRF--DAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCK--HRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYR-QVIEKTPNYTNNKINSN-RLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEK-SIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGL 2771
TG+T+N+ +AY D+RF+ S+D + + ++ILCM +K +IIGV+Q++NK N +FT DE+ FA +CG+ +H + MYEK + + K V ++VLSYH +++E +L+ VP + L F +D L MF DL +F +RF D E+L R++L+VKKNYR V YHNW HAF+VA M+++L T + F E LAL IG LCHDLDHRG N F ++ S PL+ LYSTSTMEHHHF+ + IL G+ I ++LS +Y +V+ ++ IL+TDLA +F+ R +E T+ + R L A+SMT CDL ++ K W+++ + ++ EF+ QGD EK + PI +M+R+ + ELP QV F+ +CLP Y + + + ++ +N W LA +
Sbjct: 678 TGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFKFDDIHFEDDDTLKACLRMFLDL------------------DFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLYSTSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEPLVEGVRDNRGHWIDLADV 1106 HSP 2 Score: 92.8189 bits (229), Expect = 9.987e-19 Identity = 44/99 (44.44%), Postives = 68/99 (68.69%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVK-MKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDV 1751
+G+ +NI DAY DERFN ID +TGY TK +LCMP+K ++IGV Q++NK NGE F+ DE F+++ +CG+ L +++YEK ++ +V +D+
Sbjct: 496 SGEPVNIPDAYQDERFNCEIDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDL 594
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115]) HSP 1 Score: 360.918 bits (925), Expect = 1.189e-116 Identity = 192/436 (44.04%), Postives = 264/436 (60.55%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK G FT DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L T+P I +L + + P +YM V G S F+ E L RF ++V+KNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+L+ Y++VL I+ I+ATDLA +F R+ + + + NN+ + +R++ L MT CDLCS+ K W + I EFW +GDE K IG PI +MDRD K E+P+GQVGF + V +PCY LS + P S ++ NL QW
Sbjct: 347 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGTVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLPSAIYKEIELFHFDIAPFEELWPAIFVYM-----------VHNSCGKTS-------FELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTTGIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQ-EGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAHRDRVI--GLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDEVPQGQVGFYNAVAIPCYTTLSELFPPSVPLLEACRENLSQW 761 HSP 2 Score: 81.2629 bits (199), Expect = 1.189e-116 Identity = 41/111 (36.94%), Postives = 68/111 (61.26%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L I+EL+R + PF+ +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D ++KELY+ +FD G
Sbjct: 207 IGDLIAILELHRHLGREPFNLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFDIG 317
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115]) HSP 1 Score: 360.918 bits (925), Expect = 1.190e-116 Identity = 192/436 (44.04%), Postives = 264/436 (60.55%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK G FT DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L T+P I +L + + P +YM V G S F+ E L RF ++V+KNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+L+ Y++VL I+ I+ATDLA +F R+ + + + NN+ + +R++ L MT CDLCS+ K W + I EFW +GDE K IG PI +MDRD K E+P+GQVGF + V +PCY LS + P S ++ NL QW
Sbjct: 347 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGTVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLPSAIYKEIELFHFDIAPFEELWPAIFVYM-----------VHNSCGKTS-------FELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTTGIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQ-EGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAHRDRVI--GLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDEVPQGQVGFYNAVAIPCYTTLSELFPPSVPLLEACRENLSQW 761 HSP 2 Score: 80.8777 bits (198), Expect = 1.190e-116 Identity = 41/111 (36.94%), Postives = 68/111 (61.26%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L I+EL+R + PF+ +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D ++KELY+ +FD G
Sbjct: 207 IGDLIAILELHRHLGREPFNLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFDIG 317
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115]) HSP 1 Score: 356.295 bits (913), Expect = 2.996e-115 Identity = 188/422 (44.55%), Postives = 258/422 (61.14%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPES 2711
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK G FT DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L T+P I +L + + P +YM V G S F+ E L RF ++V+KNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+L+ Y++VL I+ I+ATDLA +F R+ + + + NN+ + +R++ L MT CDLCS+ K W + I EFW +GDE K IG PI +MDRD K E+P+GQVGF + V +PCY LS + P S
Sbjct: 347 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGTVIGVVQMVNKLGGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLTLPSAIYKEIELFHFDIAPFEELWPAIFVYM-----------VHNSCGKTS-------FELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTTGIFTELERKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSNLTSGEYEQVLEIIRKAIIATDLALYFGNRKQLAELLSTGALDLNNRAHRDRVI--GLMMTACDLCSVTKLWPVTRLTANDIYAEFWAEGDEMKKIGMQPISMMDRDKKDEVPQGQVGFYNAVAIPCYTTLSELFPPS 748 HSP 2 Score: 81.2629 bits (199), Expect = 2.996e-115 Identity = 41/111 (36.94%), Postives = 68/111 (61.26%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L I+EL+R + PF+ +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D ++KELY+ +FD G
Sbjct: 207 IGDLIAILELHRHLGREPFNLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFDIG 317
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 292.738 bits (748), Expect = 1.246e-84 Identity = 169/443 (38.15%), Postives = 254/443 (57.34%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTL--YEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTS-TMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT--NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQL-PIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
TG +NI DAY D RF+ D +G+ +++LC+P+ +IIGV Q+LN+ +G+ F D+ F F +CGL ++ + MY+++ +S K VA+DVLSYH S E +K K A +P + +DKLSF +++ D+ L MF +EL V++ + D E L R++LTV+KNYR V YHNW HAF+V M+S+L T + TL E LAL +G +CHDLDHRG N F +T LS LY TS T+EHHHFN + ILQ +GHNIFS+LS Y +++ +K ILATDL +F+ R + N N + +R + ++ MT CDL ++ K W++ + ++ EF+ QGD E+S +L P + DR+ K ELP Q+ ++ +C P Y + + P+ ++ + N +W L
Sbjct: 432 TGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMVTAALRMF-----MELGMVQKF-----------KIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSMLTTAGFQETLTEMETLALIVGCICHDLDHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFSNLSSHEYGELMQLLKQSILATDLTLYFQNRNSFFELVNKGEYNWNVKEHREMCRSMLMTACDLGAVTKPWEISHKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETFAKLNPKLQPMMDLIKANRAKWEEL 858 HSP 2 Score: 77.411 bits (189), Expect = 6.142e-14 Identity = 38/101 (37.62%), Postives = 62/101 (61.39%), Query Frame = 3
Query: 1464 GQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKK-NGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLS 1757
G+T+NI DAY D RF+ ID +TGY TK++LCMP+ E+IGV Q +NK NG FT DE + +CG+A+ ++++ + + + ++V++
Sbjct: 244 GETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIHNSDGEVIGVAQAINKSPNGALFTQDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVN 344
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 283.493 bits (724), Expect = 1.777e-81 Identity = 165/441 (37.41%), Postives = 246/441 (55.78%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTL--YEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTS-TMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQL-PIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
TG +NI DAY D RF+ D +G+ +++LC+P+ +IIGV Q+LN+ +G+ F D+ F F +CGL ++ + MY+++ +S K VA+DVLSYH S E +K K A +P + +DKLSF +++ D+ L MF +EL V++ + D E L R++LTV+KNYR V YHNW HAF+V M+S+L T + TL E LAL +G +CHDLDHRG N F +T LS LY TS T+EHHHFN + ILQ +GHNIFS+LS Y +++ +K ILATDL +F+ ++ MT CDL ++ K W++ + ++ EF+ QGD E+S +L P + DR+ K ELP Q+ ++ +C P Y + + P+ ++ + N +W L
Sbjct: 429 TGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMVTAALRMF-----MELGMVQKF-----------KIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSMLTTAGFQETLTEMETLALIVGCICHDLDHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFSNLSSHEYGELMQLLKQSILATDLTLYFQ------------------------SMLMTACDLGAVTKPWEISHKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETFAKLNPKLQPMMDLIKANRAKWEEL 829 HSP 2 Score: 73.559 bits (179), Expect = 8.505e-13 Identity = 39/101 (38.61%), Postives = 62/101 (61.39%), Query Frame = 3
Query: 1464 GQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKK-NGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLS 1757
G+T+NI DAY D RF+ ID +TGY TK++LCMP+ E+IGV Q +NK NG FT DE + F CG+A+ ++++ + + + ++V++
Sbjct: 244 GETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIHNSDGEVIGVAQAINKSPNGALFTQDDEKMYLPF---CGIAISNAQLFAASRKEYDRSRALLEVVN 341
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE10A (phosphodiesterase 10A [Source:NCBI gene;Acc:100485841]) HSP 1 Score: 365.54 bits (937), Expect = 9.138e-117 Identity = 192/438 (43.84%), Postives = 273/438 (62.33%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +DV TGY T+ ILCMP+ ++ +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + +E++ L T+P + ++ F D QP F+DL+ + + + + G F+ E L RF ++VKKNYR+VPYHNW HA +V+H MY +L+ + FT E L + LCHDLDHRG TN ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+LS Y++VL I+ I+ATDLA +F R+ +E NN+ + +RL+ L MT CDLCS+ K W + + I EFWT+GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY LS I P + ++ + NL QW
Sbjct: 345 TGEVLNIPDAYADPRFNREVDVYTGYTTRNILCMPIVIRGSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTLEKLSYHSICTSDEWQNLMNCTLPVSLCREIELYHF-------DIQP------FEDLWPAIYVYMIHQSCGKNC-------FELEKLCRFTMSVKKNYRRVPYHNWKHAVTVSHCMYVILQNNQEIFTDLERKGLLVACLCHDLDHRGYTNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSNLSSNEYEQVLEIIRKAIIATDLALYFGNRKHLEDLHQMGALNLNNQAHRDRLI--GLMMTACDLCSVTKLWPVTRLIADDIYAEFWTEGDEMKRLGISPIPMMDRDKQDEIPQGQMGFYNAVAVPCYTTLSEIFPSTRPLLQACKENLSQW 760 HSP 2 Score: 77.411 bits (189), Expect = 9.138e-117 Identity = 42/111 (37.84%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +++ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 205 IGDLIGILELYRHWGKGSFRLCHQQVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 315
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE10A (phosphodiesterase 10A [Source:NCBI gene;Acc:100485841]) HSP 1 Score: 356.295 bits (913), Expect = 7.379e-110 Identity = 188/424 (44.34%), Postives = 266/424 (62.74%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPES 2711
TG+ LNI DAY+D RFNR +DV TGY T+ ILCMP+ ++ +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + +E++ L T+P + ++ F D QP F+DL+ + + + + G F+ E L RF ++VKKNYR+VPYHNW HA +V+H MY +L+ + FT E L + LCHDLDHRG TN ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+LS Y++VL I+ I+ATDLA +F R+ +E NN+ + +RL+ L MT CDLCS+ K W + + I EFWT+GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY LS I P +
Sbjct: 279 TGEVLNIPDAYADPRFNREVDVYTGYTTRNILCMPIVIRGSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTLEKLSYHSICTSDEWQNLMNCTLPVSLCREIELYHF-------DIQP------FEDLWPAIYVYMIHQSCGKNC-------FELEKLCRFTMSVKKNYRRVPYHNWKHAVTVSHCMYVILQNNQEIFTDLERKGLLVACLCHDLDHRGYTNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSNLSSNEYEQVLEIIRKAIIATDLALYFGNRKHLEDLHQMGALNLNNQAHRDRLI--GLMMTACDLCSVTKLWPVTRLIADDIYAEFWTEGDEMKRLGISPIPMMDRDKQDEIPQGQMGFYNAVAVPCYTTLSEIFPST 680 HSP 2 Score: 58.151 bits (139), Expect = 6.624e-8 Identity = 40/110 (36.36%), Postives = 62/110 (56.36%), Query Frame = 2
Query: 1055 GCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +++ WA +AI+ ++ KQ +LN F+L+V+ F N +S ++ AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 148 GDLIGILELYRHWGKGSFRLCHQQVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSNH----FDN-ESFLQ---IYAKNLVNADRCALFQVDHKNKELYSDLFDIG 249
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE10A (phosphodiesterase 10A [Source:NCBI gene;Acc:100485841]) HSP 1 Score: 356.681 bits (914), Expect = 1.112e-109 Identity = 190/436 (43.58%), Postives = 270/436 (61.93%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLK 2747
TG+ LNI DAY+D RFNR +DV TGY T+ ILCMP+ ++ +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + +E++ L T+P + ++ F D QP F+DL+ + + + + G F+ E L RF ++VKKNYR+VPYHNW HA +V+H MY +L+ + FT E L + LCHDLDHRG TN ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+LS Y++VL I+ I+ATDLA +F R+ +E NN+ + +RL+ L MT CDLCS+ K W + + I EFWT+GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY LS I P + ++ LK
Sbjct: 278 TGEVLNIPDAYADPRFNREVDVYTGYTTRNILCMPIVIRGSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTLEKLSYHSICTSDEWQNLMNCTLPVSLCREIELYHF-------DIQP------FEDLWPAIYVYMIHQSCGKNC-------FELEKLCRFTMSVKKNYRRVPYHNWKHAVTVSHCMYVILQNNQEIFTDLERKGLLVACLCHDLDHRGYTNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSNLSSNEYEQVLEIIRKAIIATDLALYFGNRKHLEDLHQMGALNLNNQAHRDRLI--GLMMTACDLCSVTKLWPVTRLIADDIYAEFWTEGDEMKRLGISPIPMMDRDKQDEIPQGQMGFYNAVAVPCYTTLSEIFPSTRPLLQACNRILK 691 HSP 2 Score: 57.7658 bits (138), Expect = 7.552e-8 Identity = 40/111 (36.04%), Postives = 62/111 (55.86%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +++ WA +AI+ ++ KQ +LN F+L+V+ F N +S ++ AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 146 IGDLIGILELYRHWGKGSFRLCHQQVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSNH----FDN-ESFLQ---IYAKNLVNADRCALFQVDHKNKELYSDLFDIG 248
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE10A (phosphodiesterase 10A [Source:NCBI gene;Acc:100485841]) HSP 1 Score: 356.295 bits (913), Expect = 1.618e-109 Identity = 188/424 (44.34%), Postives = 266/424 (62.74%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPES 2711
TG+ LNI DAY+D RFNR +DV TGY T+ ILCMP+ ++ +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + +E++ L T+P + ++ F D QP F+DL+ + + + + G F+ E L RF ++VKKNYR+VPYHNW HA +V+H MY +L+ + FT E L + LCHDLDHRG TN ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+LS Y++VL I+ I+ATDLA +F R+ +E NN+ + +RL+ L MT CDLCS+ K W + + I EFWT+GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY LS I P +
Sbjct: 308 TGEVLNIPDAYADPRFNREVDVYTGYTTRNILCMPIVIRGSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTLEKLSYHSICTSDEWQNLMNCTLPVSLCREIELYHF-------DIQP------FEDLWPAIYVYMIHQSCGKNC-------FELEKLCRFTMSVKKNYRRVPYHNWKHAVTVSHCMYVILQNNQEIFTDLERKGLLVACLCHDLDHRGYTNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSNLSSNEYEQVLEIIRKAIIATDLALYFGNRKHLEDLHQMGALNLNNQAHRDRLI--GLMMTACDLCSVTKLWPVTRLIADDIYAEFWTEGDEMKRLGISPIPMMDRDKQDEIPQGQMGFYNAVAVPCYTTLSEIFPST 709 HSP 2 Score: 57.7658 bits (138), Expect = 8.018e-8 Identity = 40/111 (36.04%), Postives = 62/111 (55.86%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +++ WA +AI+ ++ KQ +LN F+L+V+ F N +S ++ AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 176 IGDLIGILELYRHWGKGSFRLCHQQVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSNH----FDN-ESFLQ---IYAKNLVNADRCALFQVDHKNKELYSDLFDIG 278
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: PDE10A (phosphodiesterase 10A [Source:NCBI gene;Acc:100485841]) HSP 1 Score: 357.066 bits (915), Expect = 2.472e-109 Identity = 190/436 (43.58%), Postives = 270/436 (61.93%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLK 2747
TG+ LNI DAY+D RFNR +DV TGY T+ ILCMP+ ++ +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + +E++ L T+P + ++ F D QP F+DL+ + + + + G F+ E L RF ++VKKNYR+VPYHNW HA +V+H MY +L+ + FT E L + LCHDLDHRG TN ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+LS Y++VL I+ I+ATDLA +F R+ +E NN+ + +RL+ L MT CDLCS+ K W + + I EFWT+GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY LS I P + ++ LK
Sbjct: 314 TGEVLNIPDAYADPRFNREVDVYTGYTTRNILCMPIVIRGSVIGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTLEKLSYHSICTSDEWQNLMNCTLPVSLCREIELYHF-------DIQP------FEDLWPAIYVYMIHQSCGKNC-------FELEKLCRFTMSVKKNYRRVPYHNWKHAVTVSHCMYVILQNNQEIFTDLERKGLLVACLCHDLDHRGYTNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSNLSSNEYEQVLEIIRKAIIATDLALYFGNRKHLEDLHQMGALNLNNQAHRDRLI--GLMMTACDLCSVTKLWPVTRLIADDIYAEFWTEGDEMKRLGISPIPMMDRDKQDEIPQGQMGFYNAVAVPCYTTLSEIFPSTRPLLQACNRILK 727 HSP 2 Score: 58.151 bits (139), Expect = 7.600e-8 Identity = 40/111 (36.04%), Postives = 62/111 (55.86%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +++ WA +AI+ ++ KQ +LN F+L+V+ F N +S ++ AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 182 IGDLIGILELYRHWGKGSFRLCHQQVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSNH----FDN-ESFLQ---IYAKNLVNADRCALFQVDHKNKELYSDLFDIG 284
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde10a (phosphodiesterase 10A [Source:MGI Symbol;Acc:MGI:1345143]) HSP 1 Score: 361.303 bits (926), Expect = 2.812e-116 Identity = 190/438 (43.38%), Postives = 273/438 (62.33%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFI-KNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN----SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L +P I ++++ F D P F++++ G+ + + R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N S+R + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 330 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHF-------DIGP------FENMWPGIFVYMIHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLHNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQW 745 HSP 2 Score: 79.337 bits (194), Expect = 2.812e-116 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 190 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 300
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde10a (phosphodiesterase 10A [Source:MGI Symbol;Acc:MGI:1345143]) HSP 1 Score: 361.303 bits (926), Expect = 2.908e-116 Identity = 190/438 (43.38%), Postives = 273/438 (62.33%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFI-KNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN----SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L +P I ++++ F D P F++++ G+ + + R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N S+R + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 278 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHF-------DIGP------FENMWPGIFVYMIHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLHNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQW 693 HSP 2 Score: 79.7221 bits (195), Expect = 2.908e-116 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 138 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 248
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde10a (phosphodiesterase 10A [Source:MGI Symbol;Acc:MGI:1345143]) HSP 1 Score: 360.918 bits (925), Expect = 3.031e-116 Identity = 190/438 (43.38%), Postives = 273/438 (62.33%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFI-KNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN----SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L +P I ++++ F D P F++++ G+ + + R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N S+R + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 347 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHF-------DIGP------FENMWPGIFVYMIHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLHNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQW 762 HSP 2 Score: 79.7221 bits (195), Expect = 3.031e-116 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 207 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 317
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde10a (phosphodiesterase 10A [Source:MGI Symbol;Acc:MGI:1345143]) HSP 1 Score: 360.918 bits (925), Expect = 3.134e-116 Identity = 190/438 (43.38%), Postives = 273/438 (62.33%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFI-KNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN----SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L +P I ++++ F D P F++++ G+ + + R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N S+R + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 267 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHF-------DIGP------FENMWPGIFVYMIHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLHNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQW 682 HSP 2 Score: 79.7221 bits (195), Expect = 3.134e-116 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 127 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 237
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde10a (phosphodiesterase 10A [Source:MGI Symbol;Acc:MGI:1345143]) HSP 1 Score: 360.918 bits (925), Expect = 3.134e-116 Identity = 190/438 (43.38%), Postives = 273/438 (62.33%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFI-KNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN----SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L +P I ++++ F D P F++++ G+ + + R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N S+R + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 267 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHF-------DIGP------FENMWPGIFVYMIHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLHNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQW 682 HSP 2 Score: 79.7221 bits (195), Expect = 3.134e-116 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 127 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 237
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P91119|PDE5_CAEEL (Probable 3',5'-cyclic phosphodiesterase pde-5 OS=Caenorhabditis elegans OX=6239 GN=pde-5 PE=3 SV=3) HSP 1 Score: 427.172 bits (1097), Expect = 1.442e-135 Identity = 212/437 (48.51%), Postives = 281/437 (64.30%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN--SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TG+ LNI +AY DERFN +D TGY TKTILCMP+ ++ +IGVVQM+NK +G FT +DE F FA YCGLALH +K+Y+KI RS+QKY+VA++VL+YH+ + +E KLK + I L+ + F + +P+Y +YMFK LF L RFD E L+RFVLTV+KNYR+V YHNW H +SVAHAM++ L FT EALAL++ LCHDLDHRGK N ++ S PL+++YSTS ME HHFN T+TILQ+DGHNI LS ++YKK L IKHCILATDLA FF + + + IN +RLL A+ MT CDL + K W++Q V +I EF+ QGD E+ G+ PI +MDR LP+ QVGF+ +C+PCY +++ I P++ + E N K+W LA
Sbjct: 287 TGEGLNIENAYEDERFNADVDSKTGYTTKTILCMPILIRGIVIGVVQMVNKHDGVFTRQDEDAFEIFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNADEVNKLKKIEINNRIVELETIDFNGMRLSELEKPLYAVYMFKTLFADTL-----------------RFDTEDLIRFVLTVRKNYRRVAYHNWAHGWSVAHAMFATLMNSPDAFTKLEALALYVSCLCHDLDHRGKNNAYMKTMSTPLASIYSTSVMERHHFNQTVTILQQDGHNILKSLSSEDYKKTLSLIKHCILATDLALFFSNKAKLNVILDNNTFDINRQEHRLLTQAVMMTGCDLVASAKPWNIQTETVKVIFEEFYDQGDAERLSGKEPIPMMDRQQAHMLPQMQVGFMRGICMPCYDLIARIFPKNDKMRERCEYNAKKWEELA 706 HSP 2 Score: 70.8626 bits (172), Expect = 3.830e-11 Identity = 37/102 (36.27%), Postives = 59/102 (57.84%), Query Frame = 2
Query: 1118 DEEIFNNYCTWAGLAIYYNEINLTNQ-------------KQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
++ I N CTWA YY+E+ Q KQ KL+ F+L+V + +F ++D++I ++M A+ LV A+R SLFL+D + ++YA+IFD G
Sbjct: 154 EKSIVNAVCTWAAATNYYSELYTHKQEGSDGQDIHENIAKQRKLSNFLLDVARSIFHDIVSMDAVIIKVMNFAQKLVDADRASLFLVDSKNAQIYARIFDVG 255
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q9Y233|PDE10_HUMAN (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Homo sapiens OX=9606 GN=PDE10A PE=1 SV=1) HSP 1 Score: 363.999 bits (933), Expect = 2.006e-116 Identity = 193/438 (44.06%), Postives = 271/438 (61.87%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVP-GFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLH----MALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L T+P K ++ F D P F++++ G+ + V R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N N H + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD K E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 337 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHF-------DIGP------FENMWPGIFVYMVHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQW 752 HSP 2 Score: 79.7221 bits (195), Expect = 2.006e-116 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 197 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 307
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q9QYJ6|PDE10_RAT (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Rattus norvegicus OX=10116 GN=Pde10a PE=1 SV=1) HSP 1 Score: 362.073 bits (928), Expect = 9.655e-116 Identity = 190/438 (43.38%), Postives = 273/438 (62.33%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFI-KNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN----SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L +P I ++++ F D P F++++ G+ + + R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N S+R + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 347 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMHFNLPARICRDIELFHF-------DIGP------FENMWPGIFVYMIHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLHNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQW 762 HSP 2 Score: 79.7221 bits (195), Expect = 9.655e-116 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 207 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 317
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q8CA95|PDE10_MOUSE (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Mus musculus OX=10090 GN=Pde10a PE=1 SV=2) HSP 1 Score: 361.303 bits (926), Expect = 1.451e-115 Identity = 190/438 (43.38%), Postives = 273/438 (62.33%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFI-KNLDKLSFWPWTVPNDSQPVYVLYMFKDLF-GLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN----SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G F+ DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L +P I ++++ F D P F++++ G+ + + R G+ F+ E L RF+++VKKNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS LS Y++VL I+ I+ATDLA +F R+ +E+ Y +N S+R + L MT CDLCS+ K W + I EFW +GDE K +G PI +MDRD + E+P+GQ+GF + V +PCY L+ I+P + ++ +NL QW
Sbjct: 341 TGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHF-------DIGP------FENMWPGIFVYMIHRSCGTSC-------FELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNNGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM--YQTGSLNLHNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQW 756 HSP 2 Score: 79.7221 bits (195), Expect = 1.451e-115 Identity = 43/111 (38.74%), Postives = 66/111 (59.46%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L GI+ELYR K F +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D +KELY+ +FD G
Sbjct: 201 IGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIG 311
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|B3LVW5|PDE6_DROAN (cGMP-specific 3',5'-cyclic phosphodiesterase OS=Drosophila ananassae OX=7217 GN=Pde6 PE=3 SV=1) HSP 1 Score: 298.901 bits (764), Expect = 2.089e-84 Identity = 178/444 (40.09%), Postives = 253/444 (56.98%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGY-ITKTILCMP-VKMKKEIIGVVQMLNKKNG-EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKL-KFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCK-HRF-TLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQV-IEKTPNYTNN-KINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEK-SIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TGQT+NI D + R + I + T+ ILCMP V KK +IGV Q++NK NG FT D S F FA +CGL +H ++MYE + K KVA++ LSYH S ++ EKL + A NL +F + + +D VL MF L+ S+ I +D +L R+VL+V+KNYR V YHNW HA +VA M+++LKT K RF T E L L + LCHDLDHRG N F +T PL+ LY+TSTMEHHHF+ + IL +G+NIF LSP++Y+ V+ ++ IL+TDLA +F+ R +E N + + + L + MT CD+ ++ K W++Q + ++ EF+ QGD EK + P+ +MDR+ K ELP+ QVGF+ +CLP YR+L + P + N + W LA
Sbjct: 563 TGQTVNICDVHEWVREHNQIRAESEIDSTQAILCMPIVNAKKTVIGVAQLINKANGVPFTESDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQDAIADADTYNLYSFTFTDFELVDDDTCRAVLRMF---MQCNLV-------SQFQIPYD------VLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILYTTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLA 990 HSP 2 Score: 78.9518 bits (193), Expect = 1.852e-13 Identity = 38/100 (38.00%), Postives = 64/100 (64.00%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNG--EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDV 1751
T Q +NI++AY D RFN ID+ TGY T ILCMP+ + +IIGV Q++NK NG EF D F + T+CG+ + ++++E ++ ++ ++ +++
Sbjct: 317 TKQMINIKEAYKDARFNCEIDLKTGYKTNAILCMPICNYEGDIIGVAQIINKTNGCMEFDEHDVEIFRRYLTFCGIGIQNAQLFEMSVQEYRRNQILLNL 416
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3J205 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106169386 PE=3 SV=1) HSP 1 Score: 506.523 bits (1303), Expect = 2.420e-164 Identity = 238/437 (54.46%), Postives = 309/437 (70.71%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLH--MALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TG+ LNI+DAY+D+RFNR +D+ TGY TKTILCMP+K++ IIGVVQM+NK NG FT DE F TFA YCGLALH +K+Y+KI RS+QKYKVA++VLSYH S EE +K K VP + L K F PW+V ND +P+YV++M KDLF R+D + L RF LTV+KNYR VPYHNW HAFSVAHAM++++KT ++F EAL LF+ LCHDLDHRGKTN F+++++ PL+A+YSTSTMEHHHFN T+TILQ +GHNIF +L + YK+VLG I+HCILATDLA FF R ++ +++ H MA MT DLCSM+K WD+Q+ LV +IM EFW QGDEEK G +P+R+MDR + ELP+ QVGFL +CLPCY +L+ ++P + ++ A+ NL++W LA
Sbjct: 444 TGEVLNIKDAYADDRFNRDVDLQTGYTTKTILCMPIKIRGNIIGVVQMVNKLNGTFTKSDEESFETFAIYCGLALHHAKLYDKIRRSEQKYKVALEVLSYHGTCSEEEVQKTKSFDVPDKLPELIKYDFSPWSVDNDQKPIYVIHMLKDLFDTADFT---------------RYDLDTLYRFTLTVRKNYRAVPYHNWAHAFSVAHAMFTVIKTTSNKFKPIEALGLFVACLCHDLDHRGKTNSFMVKSASPLAAVYSTSTMEHHHFNQTVTILQNEGHNIFKNLCSEEYKQVLGDIRHCILATDLALFFGNRARLKDLAENKQLSWDNDDHRHSIMAHCMTAADLCSMYKPWDLQVELVHVIMEEFWQQGDEEKKNGLMPLRMMDRSFAHELPDSQVGFLVGICLPCYELLAQVLPPTSPMVEGAKANLEKWKELA 865 HSP 2 Score: 84.7297 bits (208), Expect = 2.420e-164 Identity = 48/120 (40.00%), Postives = 72/120 (60.00%), Query Frame = 2
Query: 1055 GCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIY---------YN-EINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G + G+ ELYR F+ +EEI ++ W +A + +N E+ T KQ KLN+F+L VT+ +F ++D++I +IM A+ LV A+R SLF++D D KELYA+IFD G
Sbjct: 297 GLVVGVAELYRKVGNRGFTEDEEEIASSLVIWGTVAFHSAELFPSGAHNPEMYHTMTKQRKLNEFLLAVTKSIFQDIVSMDTVIMKIMNYAQKLVSADRASLFMVDLDRKELYARIFDIG 416 HSP 3 Score: 42.3578 bits (98), Expect = 2.420e-164 Identity = 25/74 (33.78%), Postives = 43/74 (58.11%), Query Frame = 3
Query: 861 LLNEMKNDLLSILNCDGANVYIIDKIHNEIY-----RNDLQNIHLNVQKIAKGTTLAAFVAHEKVPVNCSDVCM 1067
+L+E+ + S +N DG N+YI+D+ ++Y + ++ V++I GTTLAA+VAH K V ++ M
Sbjct: 196 VLHELIVCMASAVNADGYNLYIVDEDGQDLYYYKPNASSTKSHSPCVRRIGAGTTLAAYVAHTKQNVRLGEMFM 269
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1S3HGB7 (Phosphodiesterase OS=Lingula unguis OX=7574 GN=LOC106154654 PE=3 SV=1) HSP 1 Score: 496.123 bits (1276), Expect = 3.043e-163 Identity = 238/440 (54.09%), Postives = 314/440 (71.36%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIE-----KTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TG+ LNI+DAY+D+RFNR +D+ TGY TKTILCMP+K++ IIGVVQM+NK NG FT DE F TFA YCGLALH +K+Y+KI RS+QKYKVA++VLSYH S EE +K K VP + L K F PW+V ND +P+YV++M KDLF + + G+++ R+D + L RF LTV+KNYR VPYHNW HAFSVAHAM++++KT ++F EAL LF+ LCHDLDHRGKTN F+++++ PL+A+YSTSTMEHHHFN T+TILQ +GHNIF +L + YK+VLG I+HCILATDLA FF R ++ K ++ N + +R L A++MT CDLC+ FK WD Q V +I EF+ QGDEEK G PI +MDRD K LP+ +VGFL +CLPCY +L+ ++P + ++ A+ NL++W LA
Sbjct: 12 TGEVLNIKDAYADDRFNRDVDLQTGYTTKTILCMPIKIRGNIIGVVQMVNKLNGTFTKSDEESFETFAIYCGLALHHAKLYDKIRRSEQKYKVALEVLSYHGTCSEEEVQKTKSIDVPDKLPELIKYDFSPWSVDNDQKPIYVIHMLKDLF--DTADFTSSWGNKN----QKRYDLDTLYRFTLTVRKNYRAVPYHNWAHAFSVAHAMFTVIKTTSNKFKPIEALGLFVACLCHDLDHRGKTNSFMVKSASPLAAVYSTSTMEHHHFNQTVTILQNEGHNIFKNLCSEEYKQVLGDIRHCILATDLALFFGNRARLKDLAENKQLSWDN---DDHRHLVQAIAMTSCDLCASFKPWDTQQETVKVIFEEFYIQGDEEKKQGLTPIEMMDRDRKDMLPQLEVGFLVGICLPCYELLAQVLPPTSPMVEGAKANLEKWKELA 442
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A2C9JI08 (Phosphodiesterase OS=Biomphalaria glabrata OX=6526 GN=106066461 PE=3 SV=1) HSP 1 Score: 498.819 bits (1283), Expect = 1.099e-162 Identity = 238/439 (54.21%), Postives = 311/439 (70.84%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLH-----MALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
TG+ LNI+DAY D RFN +D+ TGY TK+ILCMP+ ++ +IGVVQM+NK+NG FT DE F TFA YCGLALH +K+YEKI RS+QKYKVA+DVLSYH+ + EE + LK +P IKN+ + F PW V D +PV+ LYMFK LF D ++D E LMRF LTV+KNYR VPYHNW+HAFSVAH+M+++L+T +H+ + E ++LF+ LCHDLDHRGKTNQF++Q+ PL+A+YSTSTMEHHHFN T+TILQ +GHNIF +LS YKKVLG IK ILATDLA FF+ + + N N+ +H A++MT CDLC+M+K WD+QL+LV IIM EFW QGDEEK G +PI++MDRD K ELP +VGF+ +C+PCY ++ ++MPE+ ++ A NL++W L
Sbjct: 119 TGKVLNIKDAYKDPRFNPEVDIRTGYKTKSILCMPIFIRGVVIGVVQMVNKRNGTFTKADEQAFETFAIYCGLALHHAKLYEKIRRSEQKYKVALDVLSYHSQATAEEVKTLKDKPIPKSIKNITRYDFSPWAVMEDDKPVHCLYMFKILFQ------------------DIKYDLEDLMRFTLTVRKNYRSVPYHNWSHAFSVAHSMFTVLQTTQHKLSPVECISLFVSCLCHDLDHRGKTNQFMVQSCSPLAAVYSTSTMEHHHFNQTVTILQNEGHNIFKYLSSDEYKKVLGDIKQSILATDLAVFFKNKVTLH---NIITNEPFCWETIHHRSTLTAVAMTACDLCAMYKPWDVQLSLVYIIMEEFWQQGDEEKRRGLIPIQMMDRDKKEELPMLEVGFIQSICIPCYELMYSVMPETQPMLTGARENLRKWKEL 536
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A2C9JI04 (Phosphodiesterase OS=Biomphalaria glabrata OX=6526 GN=106066461 PE=3 SV=1) HSP 1 Score: 501.516 bits (1290), Expect = 1.283e-161 Identity = 238/439 (54.21%), Postives = 311/439 (70.84%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLH-----MALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
TG+ LNI+DAY D RFN +D+ TGY TK+ILCMP+ ++ +IGVVQM+NK+NG FT DE F TFA YCGLALH +K+YEKI RS+QKYKVA+DVLSYH+ + EE + LK +P IKN+ + F PW V D +PV+ LYMFK LF D ++D E LMRF LTV+KNYR VPYHNW+HAFSVAH+M+++L+T +H+ + E ++LF+ LCHDLDHRGKTNQF++Q+ PL+A+YSTSTMEHHHFN T+TILQ +GHNIF +LS YKKVLG IK ILATDLA FF+ + + N N+ +H A++MT CDLC+M+K WD+QL+LV IIM EFW QGDEEK G +PI++MDRD K ELP +VGF+ +C+PCY ++ ++MPE+ ++ A NL++W L
Sbjct: 263 TGKVLNIKDAYKDPRFNPEVDIRTGYKTKSILCMPIFIRGVVIGVVQMVNKRNGTFTKADEQAFETFAIYCGLALHHAKLYEKIRRSEQKYKVALDVLSYHSQATAEEVKTLKDKPIPKSIKNITRYDFSPWAVMEDDKPVHCLYMFKILFQ------------------DIKYDLEDLMRFTLTVRKNYRSVPYHNWSHAFSVAHSMFTVLQTTQHKLSPVECISLFVSCLCHDLDHRGKTNQFMVQSCSPLAAVYSTSTMEHHHFNQTVTILQNEGHNIFKYLSSDEYKKVLGDIKQSILATDLAVFFKNKVTLH---NIITNEPFCWETIHHRSTLTAVAMTACDLCAMYKPWDVQLSLVYIIMEEFWQQGDEEKRRGLIPIQMMDRDKKEELPMLEVGFIQSICIPCYELMYSVMPETQPMLTGARENLRKWKEL 680
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A210R081 (Phosphodiesterase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT08615 PE=3 SV=1) HSP 1 Score: 502.671 bits (1293), Expect = 3.462e-160 Identity = 245/462 (53.03%), Postives = 318/462 (68.83%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYR---QVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA------GLPESEKAVQLQEMEDYV 2819
TG LNI DAY+D RFNR +D TGY T +ILCMP+ ++ IIGVVQM+NK +G F DE F TFA YCGLALH +K+Y+KI RS+QK+KVA+DVLSYH+ S +E+ +K T+P + + F PW+V ND +PVYVLYM KD+F E G E+ + R+D ++RF LTV+KNYR VPYHNW HAFSVAHAM+++LKT KH F+ +E+LALF+ LCHDLDHRGKTN F+++++ PL+++YSTSTMEHHHFN TITILQ +GHNIF HLS + YK +LG I+HCILATDLA FF R Q I + + RLL MA MT CDLCSM+K W +QL LV +IM EFW QGDEE+S G P+ +MDR + ELP +VGFL +CLPCY ++ I+PE+ + A++NL++W LA P E + Q+ ++ V
Sbjct: 405 TGSILNIADAYNDSRFNRDVDQQTGYRTSSILCMPIYIRGSIIGVVQMVNKIDGNFNRADEESFETFAIYCGLALHHAKLYDKIRRSEQKFKVALDVLSYHSQGSEDEYAAVKSITIPMELPEIIDFDFSPWSVTNDHKPVYVLYMIKDIF-------EGTRGGEN----EKRYDINDIVRFTLTVRKNYRNVPYHNWAHAFSVAHAMFTVLKTAKHEFSPFESLALFVACLCHDLDHRGKTNAFMVKSASPLASIYSTSTMEHHHFNHTITILQNEGHNIFKHLSSEEYKHMLGDIRHCILATDLAIFFTNRARLQEIADRDEFVWDNREHRRLL-MANCMTACDLCSMYKPWGVQLDLVYVIMEEFWQQGDEERSQGMTPMPMMDRQKQDELPHLEVGFLVGICLPCYELMGKILPETMPMANGAKDNLRRWKELAEQQKPENQPTGENTSKSQDKDEKV 854 HSP 2 Score: 94.7449 bits (234), Expect = 3.462e-160 Identity = 47/106 (44.34%), Postives = 69/106 (65.09%), Query Frame = 2
Query: 1067 GIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G+IE++R PFS +DEE+ + WA + + Y E+ + KQ KLN F+L VT+ +F ++D++I +IM AK L A+R SLFLLD ++ ELYA+IFD G
Sbjct: 274 GVIEMFRYYGNIPFSSEDEEVAASLLVWADMFVEYVELYNSMAKQRKLNDFLLAVTKSIFQDIVSMDTVIMKIMNYAKKLGNADRASLFLLDSNTNELYARIFDTG 379
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115]) HSP 1 Score: 358.992 bits (920), Expect = 9.060e-116 Identity = 189/436 (43.35%), Postives = 264/436 (60.55%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI DAY+D RFNR +D TGY T+ ILCMP+ + +IGVVQM+NK +G FT DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L ++P I +L + + + P +YM + G F+ E L RF ++V+KNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+L+ Y++VL I+ I+ATDLA +F R+ I + + NN + +R++ L MT CDLCS+ K W + I EFW++GDE K IG PI +MDRD K E+P+GQVGF + V +PCY L + P S +++ NL QW
Sbjct: 370 TGEVLNIPDAYADPRFNREVDHYTGYTTRNILCMPIVSRGTVIGVVQMVNKLSGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLSLPDPIYKEIELFHFDISPYEELWPAVFVYMIHNSCG------------------KSSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTSGIFTELEKKGLLIACLCHDLDHRGYSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQ-EGHNIFSNLTSSEYEQVLEIIRKAIIATDLALYFGNRKQIAELLSTGALDLNNHAHRDRVI--GLMMTACDLCSVTKLWPVTRLTANDIYAEFWSEGDEMKKIGMQPIPMMDRDKKDEVPQGQVGFYNAVAIPCYTTLVELFPPSAPLLSACRENLGQW 784 HSP 2 Score: 80.1073 bits (196), Expect = 9.060e-116 Identity = 40/111 (36.04%), Postives = 68/111 (61.26%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L ++EL+R + PF+ +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D ++KELY+ +FD G
Sbjct: 230 IGDLIAVLELHRHLGQEPFNLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFDIG 340
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 301.212 bits (770), Expect = 9.783e-88 Identity = 173/444 (38.96%), Postives = 255/444 (57.43%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTL--YEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTS-TMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQV---IEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQL-PIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
TG +NI DAY D RF+ D +G+ +++LC+P+ +IIGV Q+LN+ +G+ F D+ F F +CGL ++ + MY+++ +S K VA+DVLSYH S E +K K A +P + +DKLSF +++ D+ L MF +L L+ + D E L R++LTV+KNYR V YHNW HAF+V M+SLL T + TL E LAL +G +CHDLDHRG N F +T LS LY TS T+EHHHFN + ILQ +GHNIFS+LS ++Y ++ +K ILATDL +FE R + K Y N + +R + ++ MT CDL ++ K WD+ + ++ EF+ QGD E+S +L P + DR+ K ELP Q+ ++ +C P Y L+ + P+ ++ + N +W L
Sbjct: 460 TGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMFMELGMLQKFKI----------------DYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSLLTTAGFQETLSELEILALIVGCVCHDLDHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFSNLSSRDYGDLMQLLKQSILATDLTLYFENRNSFFELVKKGEYNWN-VKEHRDMFRSMLMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPSLQLEWIDGICSPLYETLAKLNPKLQPMVDVIQANRAKWDEL 886 HSP 2 Score: 79.337 bits (194), Expect = 1.254e-14 Identity = 38/101 (37.62%), Postives = 62/101 (61.39%), Query Frame = 3
Query: 1464 GQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVK-MKKEIIGVVQMLNKKNGE--FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLS 1757
G+T+NI DAY D RF+ ID +TGY TK++LCMP++ EIIGV Q +NK G FT DE + +CG+A+ ++++ + + + ++V++
Sbjct: 272 GETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVN 372
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11al (dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [Source:NCBI gene;Acc:103024879]) HSP 1 Score: 268.085 bits (684), Expect = 9.341e-76 Identity = 156/446 (34.98%), Postives = 251/446 (56.28%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTC--KHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTS-TMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQ-----VIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQL-PIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
TG +NI D D RF+ D +G+ +++LC+P+ +IIGV Q+LN+ + + F D+ F F +CGL ++ + MY ++ ++ K VA+D+LSYH S E ++LK A +P + +DK F +++ ND+ L MF LEL V++ + D E+L R++LTV+KNYR V YHNW HAF+V+ M+ ++ T + T E LAL +G LCHDLDHRG N F ++ L+ LY TS T+EHHHFN + ILQ +GHNIF++L + Y ++ +K IL+TDL +F+ R V+ +++ I +R + ++ MT CDL ++ + W++ + ++ EF+ QGD E++ +L P + DR+ K ELP Q+ ++ +C P Y L + + ++ + N K+W L
Sbjct: 431 TGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLSYHATCSKVEVDRLKAAKIPLSSELGIDKFHFNDFSLDNDAMITASLRMF-----LELGVVQKF-----------KIDYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFVMITTAGFQEVLTDTETLALMVGCLCHDLDHRGTNNAFQAKSGSALALLYGTSATLEHHHFNHAVMILQSEGHNIFANLCSKEYSHMMQLLKQAILSTDLTLYFQRRTKFFECVLSGEFSWS---IQEHRDVLRSMLMTACDLGAVTRPWEISKQVAELVTSEFFEQGDRERAELKLTPSAIFDRNRKDELPALQLEWIDGICKPLYEALVKLNRKLQPMVDGIDANRKKWEEL 857 HSP 2 Score: 74.3294 bits (181), Expect = 4.632e-13 Identity = 36/101 (35.64%), Postives = 62/101 (61.39%), Query Frame = 3
Query: 1464 GQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNK--KNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLS 1757
G+T+NI +AY D RF+ ID +TGY T++ILCM + E+IGVVQ +NK K FT DE + +CG+++ +K++ + + + + ++V++
Sbjct: 247 GETVNIPNAYEDHRFSDEIDKLTGYKTQSILCMAICNSDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSRALLEVVN 347
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11al (dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [Source:NCBI gene;Acc:103024879]) HSP 1 Score: 262.692 bits (670), Expect = 2.890e-74 Identity = 151/421 (35.87%), Postives = 241/421 (57.24%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTC--KHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTS-TMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQ-----VIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQL-PIRLMDRDYKLELPEGQVGFLSCVCLPCYRM 2687
TG +NI D D RF+ D +G+ +++LC+P+ +IIGV Q+LN+ + + F D+ F F +CGL ++ + MY ++ ++ K VA+D+LSYH S E ++LK A +P + +DK F +++ ND+ L MF LEL V++ + D E+L R++LTV+KNYR V YHNW HAF+V+ M+ ++ T + T E LAL +G LCHDLDHRG N F ++ L+ LY TS T+EHHHFN + ILQ +GHNIF++L + Y ++ +K IL+TDL +F+ R V+ +++ I +R + ++ MT CDL ++ + W++ + ++ EF+ QGD E++ +L P + DR+ K ELP Q+ ++ +C P Y +
Sbjct: 431 TGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLSYHATCSKVEVDRLKAAKIPLSSELGIDKFHFNDFSLDNDAMITASLRMF-----LELGVVQKF-----------KIDYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFVMITTAGFQEVLTDTETLALMVGCLCHDLDHRGTNNAFQAKSGSALALLYGTSATLEHHHFNHAVMILQSEGHNIFANLCSKEYSHMMQLLKQAILSTDLTLYFQRRTKFFECVLSGEFSWS---IQEHRDVLRSMLMTACDLGAVTRPWEISKQVAELVTSEFFEQGDRERAELKLTPSAIFDRNRKDELPALQLEWIDGICKPLYEV 832 HSP 2 Score: 73.9442 bits (180), Expect = 5.573e-13 Identity = 36/101 (35.64%), Postives = 62/101 (61.39%), Query Frame = 3
Query: 1464 GQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNK--KNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLS 1757
G+T+NI +AY D RF+ ID +TGY T++ILCM + E+IGVVQ +NK K FT DE + +CG+++ +K++ + + + + ++V++
Sbjct: 247 GETVNIPNAYEDHRFSDEIDKLTGYKTQSILCMAICNSDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSRALLEVVN 347
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 259.996 bits (663), Expect = 4.967e-73 Identity = 162/444 (36.49%), Postives = 241/444 (54.28%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTL--YEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTS-TMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIK-HCILATDLAK--FFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQL-PIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
TG +NI DAY D RF+ D +G+ +++LC+P+ +IIGV Q+LN+ +G+ F D+ F F +CGL ++ + MY+++ +S K VA+DVLSYH S E +K K A +P + +DKLSF +++ D+ L MF +L L+ + D E L R++LTV+KNYR V YHNW HAF+V M+SLL T + TL E LAL +G +CHDLDHRG N F +T LS LY TS T+EHHHFN + ILQ S + N ++ H + H L + FFE + K Y N + +R + ++ MT CDL ++ K WD+ + ++ EF+ QGD E+S +L P + DR+ K ELP Q+ ++ +C P Y L+ + P+ ++ + N +W L
Sbjct: 438 TGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMFMELGMLQKFKI----------------DYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSLLTTAGFQETLSELEILALIVGCVCHDLDHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQ-------SEVGTVNNLQMFMHSRLHSCFKGQLNRNSFFE----LVKKGEYNWN-VKEHRDMFRSMLMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPSLQLEWIDGICSPLYETLAKLNPKLQPMVDVIQANRAKWDEL 853 HSP 2 Score: 79.337 bits (194), Expect = 1.470e-14 Identity = 38/101 (37.62%), Postives = 62/101 (61.39%), Query Frame = 3
Query: 1464 GQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVK-MKKEIIGVVQMLNKKNGE--FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLS 1757
G+T+NI DAY D RF+ ID +TGY TK++LCMP++ EIIGV Q +NK G FT DE + +CG+A+ ++++ + + + ++V++
Sbjct: 250 GETVNIPDAYQDHRFSDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVN 350
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 268.085 bits (684), Expect = 5.631e-79 Identity = 161/457 (35.23%), Postives = 250/457 (54.70%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMK-KEIIGVVQMLNKKNGEFTHKDESDFAT-FATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKL---KFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTL--YEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYST--STMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAK----FFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA------GLP 2774
TG+ LNI+DAYS F R +D TG+ T++ILC P+K + +E+IGV ++ NK NG + K + D AT F+ YCG+++ S +Y+K+ +QQ+ +++ +++ YH S EE K+ + TV + K ++ P ++ D +L M +D+ IN + + D L R+ L V+K YR PYHNW HA+SV+H Y L K L E ALF+ LCHDLDHRG N F + + L+ALYS+ S ME HHF I I+ G NI +LS + Y+++L ++ ILATDLA F + R++ + N N +S L + L MT CDL K W + +I +EF++QGD EK++G P +MDR+ K +PE Q+ F+ + +P +++L +++P + + N + W ++ GLP
Sbjct: 156 TGEVLNIKDAYSHPLFYRGVDDSTGFRTRSILCFPIKDENEEVIGVAELCNKINGPWFSKFDEDLATAFSIYCGISIANSLLYKKVAEAQQRSQLSNEMMMYHMKVSPEEMNKVLNSRIQTVTDIHPDFAKFTYTPRSLGEDQTITAILGMVEDM---GFIN-------------NYKLDLRTLTRWCLMVRKGYRDPPYHNWMHAYSVSHFCYLLYKNLDLGKYLQDMEIFALFVSCLCHDLDHRGTNNSFQVDSKSVLAALYSSEGSVMERHHFAQAIAIINSAGCNILENLSRKEYQRMLDLMRDIILATDLAHHLRIFKDLRKIADAGYNPDNGHQHS---LLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPSEMMDRE-KAYIPELQISFMEHIAMPLFKLLKDMLPGAAELYERVAANKEHWMRVSHKFTIRGLP 592 HSP 2 Score: 59.6918 bits (143), Expect = 2.524e-9 Identity = 39/110 (35.45%), Postives = 58/110 (52.73%), Query Frame = 2
Query: 1193 QKQEKLN---KFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMISRRRCCWKSSRNWTNIK--YSRCLFRRTI 1507
QK++KL + +L V + LF +V ++ EI+ A++L AER S+FLLD+ S EL AK+FD G S +E + ++ NIK YS LF R +
Sbjct: 66 QKEQKLKFECQALLQVAKNLFTHLDDVSVLLHEIIQEARNLSNAERCSVFLLDRSSHELVAKVFDGGVVSDESYEVRIPADQGIAGHVATTGEVLNIKDAYSHPLFYRGV 175
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde5ab (phosphodiesterase 5A, cGMP-specific, b [Source:ZFIN;Acc:ZDB-GENE-060824-4]) HSP 1 Score: 249.98 bits (637), Expect = 1.239e-70 Identity = 153/456 (33.55%), Postives = 241/456 (52.85%), Query Frame = 3
Query: 1473 LNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKK--EIIGVVQMLNK---KNGE---FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDA--EILMRFVLTVKKNYRK-VPYHNWNHAFSVAHAMYSLLKT--CKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSG-PLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQ-----VIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEK-SIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPES 2780
LNI D + D RFN ++ Y TK++LC P++ +K E+IGV Q++NK GE F DE FA +CG+A+ ++MYE + R+ K V ++VLSYH +E KL+ ++L S VP+ + + F D E + + F E+ R++L+V+KNYR+ + YHNW HAF+ M+++L T ++ T E L L I +L HDLDHRG N +I S PL+ LY S +EHHHF+ + +L G+ + S LS Q Y+ +G I+H IL+TDLA + + R V ++T N + +R L A+ MT CD+ ++ K W +Q + ++ EF+ QGD E+ + P +M+R+ + ++P QVGF+ +CLP Y LS + P +++ ++N + W L P+
Sbjct: 376 LNIPDVHRDNRFNLPVEERGDYRTKSLLCAPIQNRKKNEVIGVCQLVNKLEEGAGEVRPFNRNDEQFVEAFAIFCGMAIRNTRMYEAVARAVAKQTVTLEVLSYHAIAHEDECAKLQS-------QHLTTTS-----VPSAQSLNLLDFTFSDFGMAEELTAVGSLRMLLDLSLLQTFSIPNEVACRWILSVRKNYRRNIAYHNWRHAFNTGQCMFTVLVTGQAQNVLTPLEMLCLIIAALSHDLDHRGFNNSYIKNRSDHPLATLYGHSMLEHHHFDQCLMLLNSPGNEMLSSLSVQEYRSAVGMIEHAILSTDLATYCKNRGEFFSLVKDRTFNLEDQH---HRKLLRAMMMTACDVSAITKPWPVQQKIAELVASEFFDQGDRERQELHVEPTDMMNREKRDKIPTIQVGFIDGICLPLYEALSCVFPACAPLLSGCQSNRQNWEKLTTSPQG 816 HSP 2 Score: 97.0561 bits (240), Expect = 8.313e-21 Identity = 44/103 (42.72%), Postives = 70/103 (67.96%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKK-EIIGVVQMLNKKN---GEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLS 1757
TG +NI +AY D RFN +D++TGY T+++LC+P+K K EI+GV Q +NKK G+FT KDE +F + +CG+ LH +++YE L ++ +V +++ S
Sbjct: 190 TGNGVNIPNAYQDPRFNVEVDLMTGYKTQSVLCLPIKDNKGEIVGVAQAINKKGNNEGKFTEKDEREFGAYLAFCGIVLHNAQLYEDSLLENRRNQVLLELAS 292
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 200.29 bits (508), Expect = 8.478e-57 Identity = 120/320 (37.50%), Postives = 179/320 (55.94%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMK-KEIIGVVQMLNKKNGEFTHKDESDFAT-FATYCGLALHISKMYEKILRSQQKYKVAIDVLSYH----NGYSVEEFEKL---KFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTL--YEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYST--STMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLA 2381
TG+ LNI+DAYS F R +D TG+ T++ILC P+K + +E+IGV ++ NK NG + K + D AT F+ YCG+++ S +Y+K+ +QQ+ +++ +++ YH S EE K+ + TV + K ++ P ++ D +L M +D+ + ++ RT L R+ L V+K YR PYHNW HA+SV+H Y L K L E ALF+ LCHDLDHRG N F + + L+ALYS+ S ME HHF I I+ G NI +LS + Y+++L ++ ILATDLA
Sbjct: 74 TGEVLNIKDAYSHPLFYRGVDDSTGFRTRSILCFPIKDENEEVIGVAELCNKINGPWFSKFDEDLATAFSIYCGISIANSLLYKKVAEAQQRSQLSNEMMMYHMKVGTQVSPEEMNKVLNSRIQTVTDIHPDFAKFTYTPRSLGEDQTITAILGMVEDMGFINNYKLDLRT----------------LTRWCLMVRKGYRDPPYHNWMHAYSVSHFCYLLYKNLDLGKYLQDMEIFALFVSCLCHDLDHRGTNNSFQVDSKSVLAALYSSEGSVMERHHFAQAIAIINSAGCNILENLSRKEYQRMLDLMRDIILATDLA 377
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde10a (phosphodiesterase 10A [Source:ZFIN;Acc:ZDB-GENE-040426-1115]) HSP 1 Score: 124.79 bits (312), Expect = 5.096e-47 Identity = 64/147 (43.54%), Postives = 91/147 (61.90%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYM 1898
TG LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK +G FT DE++F FA +C LALH + MY +I S+ ++V ++ LSYH+ + EE + L T+P I +L + D P + L+M
Sbjct: 286 TGMVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKLSGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIFRVTLEKLSYHSVCTAEESQSLMQCTLPTPIVKEIELYHFDIGPFEDMWPAFFLHM 432 HSP 2 Score: 82.0333 bits (201), Expect = 5.096e-47 Identity = 41/110 (37.27%), Postives = 68/110 (61.82%), Query Frame = 2
Query: 1055 GCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L G++EL R K PF+ + +E+ WA +AI+ +++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D + ELY+ +FD G
Sbjct: 145 GDLLGVLELQRRWGKEPFTIRHQEVATALLAWASVAIHQVQVSHGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNNELYSDLFDIG 254
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde1a (phosphodiesterase 1A, calmodulin-dependent [Source:ZFIN;Acc:ZDB-GENE-090831-2]) HSP 1 Score: 109.383 bits (272), Expect = 4.775e-25 Identity = 77/275 (28.00%), Postives = 137/275 (49.82%), Query Frame = 3
Query: 1995 LMRFVLTVKKNY--RKVPYHNWNHAFSVAHAMYSLL--KTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYST-STMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIR-LMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESEKAVQLQ 2801
L+ FV ++ Y K PYHN HA V ++ LL H + E LA+ + HDL+H G TN F +QT ++ LY+ + +E+HH + ++Q D NIF +LS +++++ + +LATD++ F Q I+ + + ++ M+L + D+ K W + +M EF+ QGD E +G LP L DR+ + + + Q+GF+ + P + +L+++ + V++ AE + T G+P A ++
Sbjct: 193 LVSFVEALEAGYSKHKNPYHNLAHAADVTQTVHYLLLQSGLMHWLSELETLAVIFAAAIHDLEHTGTTNNFHIQTRSDVALLYNDRAVLENHHVSAAYRLMQDDDMNIFINLSKDDWRELRALVVEMVLATDMSCHF---QQIKTMKSALQQPESIDKSKAMSLLLHAGDISHPTKEWPLHQRWTEALMEEFFRQGDREAKLG-LPFSPLCDRNSTM-VAQSQIGFMDFIVEPTFSVLTDMAEK--VVVPLAEEAARAGT--PGVPRRGSAATVE 458
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO44626 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVE3]) HSP 1 Score: 411.764 bits (1057), Expect = 6.163e-142 Identity = 208/428 (48.60%), Postives = 284/428 (66.36%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFT---HKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFF----EYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVII 2723
+G+TLNI DAY D+RFNR ID+ TGY T+T+LCMP+ ++ IIGVVQM+NKK+G DE F TFA YCGLALH +K+Y+KI RS+QK++VA++VLSYH+ S E +LK P +L+ F +++ ++ P V++ ++LF L RFD + L RFVLTV+KNYRKVPYHNW HAF+VAH MY ++++ + FT EALA+F LCHDLDHRG+TN ++ PL+A+YSTSTMEHHHFN TITILQ +GHNIFS L+ YK VLG++K CILATDLA FF + + V++K ++ + RLL A+ MT CDL + K W +Q +V +I +EF+ +GD EK+ G+ PI + DR+ ELP QVGFL +CLPCY +L ++P + ++
Sbjct: 205 SGETLNISDAYHDDRFNREIDIQTGYTTRTLLCMPIFIRGNIIGVVQMVNKKSGVLIMCFSSDEKSFQTFAIYCGLALHHAKLYDKIRRSEQKHRVALEVLSYHSKCSEGELHRLKELDCPDPYPDLETYEFDSYSLDSEVMPKLVIFQTRNLFSLS------------------RFDLDELYRFVLTVRKNYRKVPYHNWTHAFAVAHCMYLVIRSGHNNFTGLEALAMFFACLCHDLDHRGRTNSWMKNEGTPLAAVYSTSTMEHHHFNQTITILQHEGHNIFSQLNSAEYKTVLGYMKECILATDLALFFGNKAKLKDVVDKG-TFSWDDQEHRRLLR-AICMTACDLSACTKPWRIQYKIVEVIYQEFYAEGDLEKAQGKQPIPMKDRNTAHELPAHQVGFLVGICLPCYELLGKVIPGTKPLV 612 HSP 2 Score: 112.464 bits (280), Expect = 6.163e-142 Identity = 52/111 (46.85%), Postives = 76/111 (68.47%), Query Frame = 2
Query: 1055 GCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGN 1387
G L G IEL R+ + PF +DEE+FN+Y W G+++YY E+ L K KL +F+LNVT+ +F ++D++I +IM A++LV A+R SLFL+D + ELYA+IFD G
Sbjct: 66 GELVGTIELSRMVGRDPFDEEDEEVFNSYLVWGGISLYYAEMYLHMHKHRKLTEFLLNVTRSIFQDIVSMDTVIMKIMNYAQTLVDADRTSLFLVDNKTNELYARIFDIGG 176
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32088 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW30]) HSP 1 Score: 343.199 bits (879), Expect = 2.244e-120 Identity = 185/432 (42.82%), Postives = 251/432 (58.10%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPND--SQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKI-----NSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAE 2735
TG LNIRDAY DERFNR +D+ TGY T TILC+PV+ K IIGV QM+N NG F+ D F FA YCGLALH SKMY + +QQK++VA++V+SYH S +E E+ F+ + D + P P S ++VL R D E + RF L+V+K YR +PYHNW HAFSVAH+++ +++ K T YE L+LFI +CHD+DHRGK N F++ PL+ LY+TSTME HHF + IL+ +G N+F L ++Y++VL I+ I+ATDL FF ++ +E NK +R L L MT CDLC+ K WD+Q+ V + EF+ QGDEE+ +G P+ +MDR +LPE QVGFL + PCY +L + +PE +I E
Sbjct: 207 TGSILNIRDAYRDERFNREVDMKTGYTTHTILCVPVRCKGSIIGVCQMVNSHNGFFSPNDMQSFEMFAGYCGLALHYSKMYNSLFCAQQKHQVALEVISYHCCASEKETEE--------FLNSADLVMLPPAYYPFSYLSALIFVLIF--------------------------RVDLETIARFSLSVRKCYRDIPYHNWCHAFSVAHSLWIVIRDNK-SLTDYEKLSLFIAGICHDVDHRGKNNAFMLHCKTPLANLYTTSTMEWHHFKQGVFILESEGQNVFGQLDAESYRRVLELIQEAIIATDLMLFFGNKKELE---TLQENKAFRWEEEKHRSLIRCLLMTACDLCTSAKPWDIQVVAVNKVFEEFYIQGDEERKMGLDPLPMMDRSKHDDLPENQVGFLKGIVRPCYSLLMDFVPEMAPLITYVE 600 HSP 2 Score: 109.383 bits (272), Expect = 2.244e-120 Identity = 52/111 (46.85%), Postives = 76/111 (68.47%), Query Frame = 2
Query: 1055 GCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGN 1387
G L G++EL + PF +DEEI N+Y W +AI++ EI+ KQ+ LN F+LNV + +F + +D++I++IMA AK LV A+R SLFLLD+ S+EL+A +FD GN
Sbjct: 71 GTLVGVVELVKALGSMPFEKEDEEILNSYLVWGSIAIHHAEISKQITKQKDLNTFLLNVVRSIFDEVCTMDTVIEKIMAFAKKLVNADRCSLFLLDQASEELFANLFDDGN 181
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO39522 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Q1]) HSP 1 Score: 327.02 bits (837), Expect = 3.865e-98 Identity = 183/446 (41.03%), Postives = 264/446 (59.19%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVK-MKKEIIGVVQMLNKKNG-EFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLK--TCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFE-----YRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGD-EEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TG+TLNI DAY+DERF+ ++D ++G+ TKTILCMP+K +IIGVVQ+LNK +G F DE+ F FA +CG+A+H + MYE + ++ K KVA++VLSYH +EE KLK +P L +F ++ +D L M DL +E ++ T L RFVLT+KKNYR V YHNW HAF+VA MY++LK + FT+ E AL + L HDLDHRG N F ++++ PL+ LYSTSTMEHHHF+ I I+ G+ IF+ LS Y K++ ++ I+ATDLA +F+ +++V + ++++ +S++ L A+ MT CDL ++ K W +Q ++ EF+ QGD E++ + P+ MDR K ELP+ QVGF+ VCLP Y+ S V+ N +QW LA
Sbjct: 390 TGETLNIPDAYADERFDPTVDQVSGFTTKTILCMPIKNASGDIIGVVQLLNKVDGTPFNKNDENLFEAFAIFCGMAIHSTVMYENVNKAMAKRKVALEVLSYHAVSPLEEAIKLKEEPLPPITSLRLIDFAFDDMSISDDDTLKGCLAMLCDLKIVETFQIDYLT----------------LCRFVLTIKKNYRPVMYHNWRHAFNVAQTMYAMLKKPSIGKYFTVIEQYALIVACLSHDLDHRGTNNSFQIKSATPLAQLYSTSTMEHHHFDQCIMIINSQGNEIFNTLSADEYNKIIKLLEASIIATDLALYFQRRGDFFKKVENRELDWSD---DSSKDLLRAMMMTACDLSAITKPWLVQKRTAHLVAEEFFQQGDLEQEELHSTPLPTMDRRKKDELPQMQVGFIDAVCLPLYKAFSQFDDNLKVLKDGCRENRRQWQKLA 816 HSP 2 Score: 84.7297 bits (208), Expect = 1.019e-16 Identity = 41/102 (40.20%), Postives = 66/102 (64.71%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVK-MKKEIIGVVQMLNK----KNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDV 1751
TG+T+NI +AY D RFN+ ID TGY T++ILCMP+K E+IGV Q++NK + FT DE F + +CG+ ++ +++YE+ ++ +V +D+
Sbjct: 207 TGETVNIPNAYEDARFNKEIDKKTGYTTRSILCMPIKDHDGEVIGVAQVINKTGKSTDSAFTIDDEQIFLKYLVFCGIGINNAELYERAQLEIRRNQVLLDL 308
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO43657 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY89]) HSP 1 Score: 287.73 bits (735), Expect = 9.093e-85 Identity = 170/443 (38.37%), Postives = 250/443 (56.43%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKK-EIIGVVQMLNK-KNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKT--CKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQ---VIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQL-PIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
TG+T+NI DA D R S +V + ILCMP++ K EIIGV +++N+ N F DE+ F FA +CGL +H + +Y+++ R++ K +VA++VLSYH E EK++ VP + NL F +++ D + L MFKD +E EF D E+L R++LTVK NYR V YHNW HAF+VA +M+ +L T T E L L +G LCHDLDHRG N F +T PLS LY TST+EHHHFN + IL +G FS + Y++V+ +IKH IL+TDLA F+ R + ++ + ++ +L A+ MT CDL K W++Q +V ++ REF+ QGD E+ + P+ +MDR ELP+ QV F LP +++L+ + + ++ AE+N ++W L
Sbjct: 296 TGKTMNIPDASQDTRLADSSNVEKKGFS-PILCMPIRNNKFEIIGVAELINRLDNKPFDENDETLFEAFAIFCGLGIHNTMIYDQMARAKAKQQVALEVLSYHVAAKKTEVEKIRDTQVPKAVDINLHSFKFDDFSLAADDMLIASLRMFKDCGFIE--------------EF--HIDYEVLSRWILTVKNNYRNVIYHNWRHAFNVAQSMFCMLTTGGMASVITKLECLGLIVGCLCHDLDHRGTNNAFQAKTDSPLSKLYGTSTLEHHHFNHAVIILSTEG---FSPILSDEYRQVISYIKHSILSTDLATNFKQRPKFFALVESGEFDPYNMDHRDMLK-AMMMTACDLNGTTKPWEIQKEVVNLVTREFFEQGDMERERYNMEPMAIMDRQKIDELPKLQVQFFETTGLPVFKVLAKLNNKLQPLVDGAESNKRRWQKL 717 HSP 2 Score: 81.6481 bits (200), Expect = 8.631e-16 Identity = 39/85 (45.88%), Postives = 59/85 (69.41%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKK-EIIGVVQMLNKKNG--EFTHKDESDFATFATYCGLALHISKMYE 1706
TG+T+NI DAY+D RFN+ +D TGY TK++LC PVK + E++GV Q++NK G FT +DE + T+CG+ + +K++E
Sbjct: 109 TGETVNIPDAYADPRFNQDVDKQTGYHTKSLLCKPVKNNEGEVVGVAQIINKNPGGVPFTKEDEKVCDMYLTFCGIGITNAKLFE 193
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO38644 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC93]) HSP 1 Score: 245.743 bits (626), Expect = 4.678e-72 Identity = 153/450 (34.00%), Postives = 233/450 (51.78%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPG----FIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTC--KHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYST--STMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNK-----INSNRLLHMALSMT-----FCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQW 2753
TG+ LNI+DAY+ F R +DV TG+ T+ ILC P+K +IGV ++ NK NG+ FT DE FA YCG+++ S +Y++ + + +V +++ YH S EE ++L + DK SF P T+ + LYMF DL ++ + R T L+RF L V+K YR PYHNW HAF+VAH Y LLK + + E +ALF+ LCHDLDHRG N F + ++ L+ALYS+ S ME HHF T+ IL G NIF +L+ ++KVL I++ ILATDL+ + I N ++ R + +A ++ D+ +M K + + + EK +G P+ +MDR+ + +P+ Q+ FL + LP Y++L ++PE+ +I N++ W
Sbjct: 46 TGKLLNIKDAYTHPLFYRGLDVKTGFKTRNILCFPIKDDDGVIGVAELCNKANGKCFTKFDEDLTRAFAIYCGISIFHSMLYKRAATAWHRSQVCSELMIYHMHVSEEELQRLTAHEISSPDEEIPHGFDKFSFAPRTIQMEETVRAALYMFDDLGIIDRWKIPRDT----------------LIRFTLMVRKGYRDPPYHNWTHAFTVAHFCYLLLKNSHMESKLQDIERMALFVACLCHDLDHRGTNNAFQVSSNSTLAALYSSEGSVMERHHFAQTVCILNSSGCNIFKNLTESEFEKVLDLIRYIILATDLSHHLRILKDINNMAKGRNKNEFEKVLDLIRYIILATDLSHHLRILKDINNMAKGRNKNVPSLF------------EKVMGFTPMEMMDRE-RACIPKLQIDFLENIALPVYKVLHELLPETKEVIDTVHKNMECW 466
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde10a (phosphodiesterase 10A [Source:NCBI gene;Acc:101162470]) HSP 1 Score: 363.229 bits (931), Expect = 4.754e-117 Identity = 192/443 (43.34%), Postives = 267/443 (60.27%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFI-KNLDKLSF--WPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK G FT DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L +P I K ++ F P+ + P +YM + G ++ F+ E L RF ++V+KNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+L+ Y++VL I+ I+ATDLA +F Q + + + + NN + +R++ L MT CDLCS+ K W + I EFW +GDE K IG PI +MDRD K E+PEGQVGF + V +PCY LS + P S ++ NL W +A
Sbjct: 378 TGEVLNIPDAYADPRFNREVDLKTGYTTRNILCMPIVSRGTVIGVVQMVNKLCGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLNLPTPIYKEIETFQFDISPF---EEIWPAVFIYMVHNSCG------------------ENSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTPDSFTELEKKGLLIACLCHDLDHRGYSNAYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSNLNSSEYEQVLEIIRKAIIATDLALYFNNHQQLTELLSTSALDFNNHSHRDRVI--GLMMTACDLCSVTKQWQITRLTANDIYAEFWAEGDEMKKIGIQPIPMMDRDKKDEVPEGQVGFYNSVAIPCYTTLSKLFPPSSPLLKACRENLSHWERIA 797 HSP 2 Score: 79.7221 bits (195), Expect = 4.754e-117 Identity = 42/111 (37.84%), Postives = 67/111 (60.36%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L I+EL R K PF+ +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D ++KELY+ +FD G
Sbjct: 238 IGDLVAILELRRHWGKEPFNLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFDIG 348
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde10a (phosphodiesterase 10A [Source:NCBI gene;Acc:101162470]) HSP 1 Score: 362.844 bits (930), Expect = 7.765e-117 Identity = 192/443 (43.34%), Postives = 267/443 (60.27%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFI-KNLDKLSF--WPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK G FT DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L +P I K ++ F P+ + P +YM + G ++ F+ E L RF ++V+KNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+L+ Y++VL I+ I+ATDLA +F Q + + + + NN + +R++ L MT CDLCS+ K W + I EFW +GDE K IG PI +MDRD K E+PEGQVGF + V +PCY LS + P S ++ NL W +A
Sbjct: 350 TGEVLNIPDAYADPRFNREVDLKTGYTTRNILCMPIVSRGTVIGVVQMVNKLCGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLNLPTPIYKEIETFQFDISPF---EEIWPAVFIYMVHNSCG------------------ENSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTPDSFTELEKKGLLIACLCHDLDHRGYSNAYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSNLNSSEYEQVLEIIRKAIIATDLALYFNNHQQLTELLSTSALDFNNHSHRDRVI--GLMMTACDLCSVTKQWQITRLTANDIYAEFWAEGDEMKKIGIQPIPMMDRDKKDEVPEGQVGFYNSVAIPCYTTLSKLFPPSSPLLKACRENLSHWERIA 769 HSP 2 Score: 79.337 bits (194), Expect = 7.765e-117 Identity = 42/111 (37.84%), Postives = 67/111 (60.36%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L I+EL R K PF+ +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D ++KELY+ +FD G
Sbjct: 210 IGDLVAILELRRHWGKEPFNLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFDIG 320
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde10a (phosphodiesterase 10A [Source:NCBI gene;Acc:101162470]) HSP 1 Score: 362.459 bits (929), Expect = 1.005e-116 Identity = 192/443 (43.34%), Postives = 267/443 (60.27%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFI-KNLDKLSF--WPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYT----NNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
TG+ LNI DAY+D RFNR +D+ TGY T+ ILCMP+ + +IGVVQM+NK G FT DE++F FA +C LALH + MY +I S+ Y+V ++ LSYH+ + EE++ L +P I K ++ F P+ + P +YM + G ++ F+ E L RF ++V+KNYR+VPYHNW HA +VAH MY++L+ FT E L I LCHDLDHRG +N ++ + PL+ALYSTSTME HHF+ T++ILQ +GHNIFS+L+ Y++VL I+ I+ATDLA +F Q + + + + NN + +R++ L MT CDLCS+ K W + I EFW +GDE K IG PI +MDRD K E+PEGQVGF + V +PCY LS + P S ++ NL W +A
Sbjct: 347 TGEVLNIPDAYADPRFNREVDLKTGYTTRNILCMPIVSRGTVIGVVQMVNKLCGSAFTKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWKTLTQLNLPTPIYKEIETFQFDISPF---EEIWPAVFIYMVHNSCG------------------ENSFELEKLCRFTMSVRKNYRRVPYHNWKHAVTVAHCMYAILQKTPDSFTELEKKGLLIACLCHDLDHRGYSNAYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSNLNSSEYEQVLEIIRKAIIATDLALYFNNHQQLTELLSTSALDFNNHSHRDRVI--GLMMTACDLCSVTKQWQITRLTANDIYAEFWAEGDEMKKIGIQPIPMMDRDKKDEVPEGQVGFYNSVAIPCYTTLSKLFPPSSPLLKACRENLSHWERIA 766 HSP 2 Score: 79.7221 bits (195), Expect = 1.005e-116 Identity = 42/111 (37.84%), Postives = 67/111 (60.36%), Query Frame = 2
Query: 1052 FGCLHGIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKG 1384
G L I+EL R K PF+ +E+ WA +AI+ ++ KQ +LN F+L+V++ F +DS+++ IM AK+LV A+R +LF +D ++KELY+ +FD G
Sbjct: 207 IGDLVAILELRRHWGKEPFNLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHNNKELYSDLFDIG 317
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde11a (phosphodiesterase 11A [Source:NCBI gene;Acc:101163533]) HSP 1 Score: 285.804 bits (730), Expect = 4.727e-82 Identity = 165/443 (37.25%), Postives = 248/443 (55.98%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIK-NLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTC--KHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTS-TMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEK--TPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEK-SIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYL 2762
TG +NI DAY D RF+ D + + +++LC+P+ +IIGV Q+LN+ +G+ F D+ F F +CGL ++ + MY+++ +S K VA+DVLSYH S E +K K A +P + +DKLSF +++ D+ L MF +EL V++ + D E L R++LTV+KNYR V YHNW HAF+V M+++L T + T E LAL +G +CHDLDHRG N F +T L+ LY TS T+EHHHFN + ILQ +GHNIFS+LS Y ++ +K ILATDL +FE R + + N + ++R + ++ MT CDL ++ K WD+ + ++ EF+ QGD E+ + P + DR+ K ELP Q+ ++ +C P Y L + P+ + N +W L
Sbjct: 441 TGLPVNISDAYQDPRFDAEADQFSDFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMF-----MELGMVQKF-----------KIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFAMLTTAGFQEVLTDLEILALIVGCVCHDLDHRGTNNAFQAKTGSALALLYGTSATLEHHHFNHAVMILQSEGHNIFSNLSSTEYSDLMQLLKLSILATDLTLYFENRNMFFDLVSKGEYNWNVKAHRDMCRSMMMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETLVKLNPKLQPMFDRIRANRSKWEEL 867 HSP 2 Score: 79.7221 bits (195), Expect = 8.965e-15 Identity = 40/101 (39.60%), Postives = 63/101 (62.38%), Query Frame = 3
Query: 1464 GQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNK-KNGE-FTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLS 1757
G+T+NI DAY D RF+ ID +TGY TK++LCMP+ EIIGV Q +NK NGE FT DE + +CG+A+ ++++ + + + ++V++
Sbjct: 253 GETVNIPDAYQDRRFSDEIDKLTGYKTKSLLCMPIHNSDGEIIGVAQAINKTSNGELFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVN 353
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde5ab (phosphodiesterase 5A [Source:NCBI gene;Acc:101173207]) HSP 1 Score: 254.218 bits (648), Expect = 2.485e-71 Identity = 160/454 (35.24%), Postives = 251/454 (55.29%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDV---ITGYITKTILCMPVKMKKE--IIGVVQMLNKKN------GEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGF--IKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRK-VPYHNWNHAFSVAHAMYSLLKTCKHRFTL--YEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQ-VIEKTPNYTNNKINS-NRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEE-KSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLA 2765
T Q LNI D D+RF + D ++ I K++LC P++ +K+ +IGV Q++NK + F DE FA +CGL + ++MYE + R+ K +V ++VLSYH + EE ++L+ ATVP ++ LD SF + + + + + MF DL ++ N + + S L +++L+VKKNYRK V YHNW HAF+ A M++LLK+ + + L E LAL I +L HDLDHRG N +I ++ PL+ LY STMEHHHF+ + IL G+ I S LS YK L I+ ILATDLA + + R+ E T N ++ +R L ++ MT CD+ ++ K W +Q + ++ EF+ QGD+E + + P LM+R+ + ++P QV F+ +C+ Y L+ ++ ++ + N + W LA
Sbjct: 399 TMQPLNISDVTKDQRFPWTSDCPDHMSNQI-KSLLCAPIRNRKKDKVIGVCQLVNKLDEASGSIKSFNRNDEQFLEAFAIFCGLGIQNTQMYETVERAMAKQEVTLEVLSYHASATEEESQELQVATVPSAQSLRLLD-FSFSDFDLSDTETTLATIRMFTDLNLVQ--NFQMKYTS--------------LCQWILSVKKNYRKSVAYHNWRHAFNTAQCMFALLKSGRLQNNLSDLEILALMIATLSHDLDHRGVNNSYIQRSEHPLAQLYCHSTMEHHHFDQCLMILNTPGNQILSGLSLDEYKATLKMIEKAILATDLALYMKKREDFFELTKNNQFVWVDEHHRDLLRSMLMTACDISAITKPWPVQKRVAELVATEFFEQGDKERRELNIEPTDLMNREKRDKIPSMQVSFIDAICIQLYETLAGLLEHCSPLLEGCQKNRQHWKRLA 834 HSP 2 Score: 95.9005 bits (237), Expect = 9.653e-20 Identity = 42/103 (40.78%), Postives = 71/103 (68.93%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVK-MKKEIIGVVQMLNK---KNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLS 1757
TGQ LNI++AY D RFN +D+ITGY T++ILC+P+K + E++GV Q +NK ++G FT +D+ DF+ + + G+ LH +++YE ++ +V +D+ +
Sbjct: 217 TGQPLNIKNAYKDPRFNAEVDLITGYKTQSILCLPIKNHRGEVVGVAQAINKTCGEDGAFTEQDQKDFSAYLAFSGIVLHNAQLYETSQLENKRNRVLLDLAT 319
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000044149.1 (SMESG000044149.1) HSP 1 Score: 983.786 bits (2542), Expect = 0.000e+0 Identity = 465/465 (100.00%), Postives = 465/465 (100.00%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESEKAVQLQEMEDYVEKVIKEKKLHVR 2855
TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESEKAVQLQEMEDYVEKVIKEKKLHVR
Sbjct: 463 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESEKAVQLQEMEDYVEKVIKEKKLHVR 927 HSP 2 Score: 615.15 bits (1585), Expect = 0.000e+0 Identity = 297/297 (100.00%), Postives = 297/297 (100.00%), Query Frame = 3
Query: 177 MSSPFKTLSHRNLLPINYHIRLADTQYDRENGILHKSPRLCNFEHKMHSEESITKYLINHPEFVESFLIKFYSKIQLIEIMNRMNHEPSGVIYIPKRSGIFIRSHSKNSENKDQSEFLNAVSGRYLSKDSLDSISDTSAFVDNRHRNKAKNEGISSVHSDNQINSNDSDHQETSIIEHRQLKDIFTSRNTCDQIVYRNLPILSQKYLLTQAESTEIEYVADYRHNTMELLNEMKNDLLSILNCDGANVYIIDKIHNEIYRNDLQNIHLNVQKIAKGTTLAAFVAHEKVPVNCSDVCM 1067
MSSPFKTLSHRNLLPINYHIRLADTQYDRENGILHKSPRLCNFEHKMHSEESITKYLINHPEFVESFLIKFYSKIQLIEIMNRMNHEPSGVIYIPKRSGIFIRSHSKNSENKDQSEFLNAVSGRYLSKDSLDSISDTSAFVDNRHRNKAKNEGISSVHSDNQINSNDSDHQETSIIEHRQLKDIFTSRNTCDQIVYRNLPILSQKYLLTQAESTEIEYVADYRHNTMELLNEMKNDLLSILNCDGANVYIIDKIHNEIYRNDLQNIHLNVQKIAKGTTLAAFVAHEKVPVNCSDVCM
Sbjct: 1 MSSPFKTLSHRNLLPINYHIRLADTQYDRENGILHKSPRLCNFEHKMHSEESITKYLINHPEFVESFLIKFYSKIQLIEIMNRMNHEPSGVIYIPKRSGIFIRSHSKNSENKDQSEFLNAVSGRYLSKDSLDSISDTSAFVDNRHRNKAKNEGISSVHSDNQINSNDSDHQETSIIEHRQLKDIFTSRNTCDQIVYRNLPILSQKYLLTQAESTEIEYVADYRHNTMELLNEMKNDLLSILNCDGANVYIIDKIHNEIYRNDLQNIHLNVQKIAKGTTLAAFVAHEKVPVNCSDVCM 297 HSP 3 Score: 246.514 bits (628), Expect = 0.000e+0 Identity = 120/120 (100.00%), Postives = 120/120 (100.00%), Query Frame = 2
Query: 1067 GIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMI 1426
GIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMI
Sbjct: 329 GIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMI 448
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000044149.1 (SMESG000044149.1) HSP 1 Score: 955.666 bits (2469), Expect = 0.000e+0 Identity = 453/458 (98.91%), Postives = 455/458 (99.34%), Query Frame = 3
Query: 1482 RDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESEKAVQLQEMEDYVEKVIKEKKLHVR 2855
R + +ERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESEKAVQLQEMEDYVEKVIKEKKLHVR
Sbjct: 452 RCCWKNERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESEKAVQLQEMEDYVEKVIKEKKLHVR 909 HSP 2 Score: 612.838 bits (1579), Expect = 0.000e+0 Identity = 297/297 (100.00%), Postives = 297/297 (100.00%), Query Frame = 3
Query: 177 MSSPFKTLSHRNLLPINYHIRLADTQYDRENGILHKSPRLCNFEHKMHSEESITKYLINHPEFVESFLIKFYSKIQLIEIMNRMNHEPSGVIYIPKRSGIFIRSHSKNSENKDQSEFLNAVSGRYLSKDSLDSISDTSAFVDNRHRNKAKNEGISSVHSDNQINSNDSDHQETSIIEHRQLKDIFTSRNTCDQIVYRNLPILSQKYLLTQAESTEIEYVADYRHNTMELLNEMKNDLLSILNCDGANVYIIDKIHNEIYRNDLQNIHLNVQKIAKGTTLAAFVAHEKVPVNCSDVCM 1067
MSSPFKTLSHRNLLPINYHIRLADTQYDRENGILHKSPRLCNFEHKMHSEESITKYLINHPEFVESFLIKFYSKIQLIEIMNRMNHEPSGVIYIPKRSGIFIRSHSKNSENKDQSEFLNAVSGRYLSKDSLDSISDTSAFVDNRHRNKAKNEGISSVHSDNQINSNDSDHQETSIIEHRQLKDIFTSRNTCDQIVYRNLPILSQKYLLTQAESTEIEYVADYRHNTMELLNEMKNDLLSILNCDGANVYIIDKIHNEIYRNDLQNIHLNVQKIAKGTTLAAFVAHEKVPVNCSDVCM
Sbjct: 1 MSSPFKTLSHRNLLPINYHIRLADTQYDRENGILHKSPRLCNFEHKMHSEESITKYLINHPEFVESFLIKFYSKIQLIEIMNRMNHEPSGVIYIPKRSGIFIRSHSKNSENKDQSEFLNAVSGRYLSKDSLDSISDTSAFVDNRHRNKAKNEGISSVHSDNQINSNDSDHQETSIIEHRQLKDIFTSRNTCDQIVYRNLPILSQKYLLTQAESTEIEYVADYRHNTMELLNEMKNDLLSILNCDGANVYIIDKIHNEIYRNDLQNIHLNVQKIAKGTTLAAFVAHEKVPVNCSDVCM 297 HSP 3 Score: 270.396 bits (690), Expect = 0.000e+0 Identity = 129/131 (98.47%), Postives = 130/131 (99.24%), Query Frame = 2
Query: 1067 GIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMISRRRCCWKSSR 1459
GIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMISRRRCCWK+ R
Sbjct: 329 GIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMISRRRCCWKNER 459
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000044149.1 (SMESG000044149.1) HSP 1 Score: 935.25 bits (2416), Expect = 0.000e+0 Identity = 447/465 (96.13%), Postives = 447/465 (96.13%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESEKAVQLQEMEDYVEKVIKEKKLHVR 2855
TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLEL FDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESEKAVQLQEMEDYVEKVIKEKKLHVR
Sbjct: 463 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLEL------------------FDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESEKAVQLQEMEDYVEKVIKEKKLHVR 909 HSP 2 Score: 615.15 bits (1585), Expect = 0.000e+0 Identity = 297/297 (100.00%), Postives = 297/297 (100.00%), Query Frame = 3
Query: 177 MSSPFKTLSHRNLLPINYHIRLADTQYDRENGILHKSPRLCNFEHKMHSEESITKYLINHPEFVESFLIKFYSKIQLIEIMNRMNHEPSGVIYIPKRSGIFIRSHSKNSENKDQSEFLNAVSGRYLSKDSLDSISDTSAFVDNRHRNKAKNEGISSVHSDNQINSNDSDHQETSIIEHRQLKDIFTSRNTCDQIVYRNLPILSQKYLLTQAESTEIEYVADYRHNTMELLNEMKNDLLSILNCDGANVYIIDKIHNEIYRNDLQNIHLNVQKIAKGTTLAAFVAHEKVPVNCSDVCM 1067
MSSPFKTLSHRNLLPINYHIRLADTQYDRENGILHKSPRLCNFEHKMHSEESITKYLINHPEFVESFLIKFYSKIQLIEIMNRMNHEPSGVIYIPKRSGIFIRSHSKNSENKDQSEFLNAVSGRYLSKDSLDSISDTSAFVDNRHRNKAKNEGISSVHSDNQINSNDSDHQETSIIEHRQLKDIFTSRNTCDQIVYRNLPILSQKYLLTQAESTEIEYVADYRHNTMELLNEMKNDLLSILNCDGANVYIIDKIHNEIYRNDLQNIHLNVQKIAKGTTLAAFVAHEKVPVNCSDVCM
Sbjct: 1 MSSPFKTLSHRNLLPINYHIRLADTQYDRENGILHKSPRLCNFEHKMHSEESITKYLINHPEFVESFLIKFYSKIQLIEIMNRMNHEPSGVIYIPKRSGIFIRSHSKNSENKDQSEFLNAVSGRYLSKDSLDSISDTSAFVDNRHRNKAKNEGISSVHSDNQINSNDSDHQETSIIEHRQLKDIFTSRNTCDQIVYRNLPILSQKYLLTQAESTEIEYVADYRHNTMELLNEMKNDLLSILNCDGANVYIIDKIHNEIYRNDLQNIHLNVQKIAKGTTLAAFVAHEKVPVNCSDVCM 297 HSP 3 Score: 246.514 bits (628), Expect = 0.000e+0 Identity = 120/120 (100.00%), Postives = 120/120 (100.00%), Query Frame = 2
Query: 1067 GIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMI 1426
GIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMI
Sbjct: 329 GIIELYRLAYKYPFSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMI 448
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000045774.1 (SMESG000045774.1) HSP 1 Score: 456.833 bits (1174), Expect = 1.561e-151 Identity = 219/445 (49.21%), Postives = 302/445 (67.87%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN----SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESE 2783
TG+ LNIR+AY D RFNR ID+ TGY TKT++ +PVK+K E +GV+Q++NK +G F DE TFA YCG+AL+I+KMY +I S+Q+YKVA+DVLSYH+G+ + E + L A +P + + + PW + Q LYMF+ LFG+ I+ + + E RF+ + LMRF+LTVKKNYRKVPYHNW+HAF+V +M+ +L H +TL E+LALFIG CHDLDHRGKTN++I+++ L +LY+TSTMEHHHFNMT++ILQ+D HNIF H++ +YK VL IKH ILATDL +FF + K NN+++ ++R + M L MT DL +M+K WDMQL V +IM+EFW QGD EK G +P R+MDR Y ELP ++GF++ +CLPCY L I+ + +++ + NL QW L LP+ +
Sbjct: 24 TGEILNIRNAYDDMRFNRDIDLKTGYQTKTLVAIPVKLKNETVGVLQIVNKVDGHFNDSDEEHLTTFANYCGIALYIAKMYRRIRHSEQRYKVALDVLSYHSGFDLVELQLLSEAKIPYEWSEMAEYYYCPWDIDEIRQLEAFLYMFRTLFGIFNIDEKENLIKPKFSEIIWRFEKKTLMRFILTVKKNYRKVPYHNWSHAFTVGQSMFCMLMNTSHEYTLIESLALFIGCFCHDLDHRGKTNEYIVKSDTALGSLYTTSTMEHHHFNMTVSILQRDEHNIFEHMNSTDYKTVLDLIKHDILATDLNRFFVNNVKVSKL--IENNEMDWKNFNHRYIFMELFMTAGDLSAMYKPWDMQLNFVKVIMQEFWDQGDVEKQEGSVPARMMDRAYNYELPAMEIGFITFICLPCYTSLDKIVSGAFPVVSGLQKNLDQWKTLKDLPKED 466
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000045774.1 (SMESG000045774.1) HSP 1 Score: 436.417 bits (1121), Expect = 4.442e-143 Identity = 219/482 (45.44%), Postives = 302/482 (62.66%), Query Frame = 3
Query: 1461 TGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISK-------------------------------------MYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGFIKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELINVERRTGSESYIEFDDRFDAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLLKTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYSTSTMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVIEKTPNYTNNKIN----SNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQLPIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPESE 2783
TG+ LNIR+AY D RFNR ID+ TGY TKT++ +PVK+K E +GV+Q++NK +G F DE TFA YCG+AL+I+K MY +I S+Q+YKVA+DVLSYH+G+ + E + L A +P + + + PW + Q LYMF+ LFG+ I+ + + E RF+ + LMRF+LTVKKNYRKVPYHNW+HAF+V +M+ +L H +TL E+LALFIG CHDLDHRGKTN++I+++ L +LY+TSTMEHHHFNMT++ILQ+D HNIF H++ +YK VL IKH ILATDL +FF + K NN+++ ++R + M L MT DL +M+K WDMQL V +IM+EFW QGD EK G +P R+MDR Y ELP ++GF++ +CLPCY L I+ + +++ + NL QW L LP+ +
Sbjct: 24 TGEILNIRNAYDDMRFNRDIDLKTGYQTKTLVAIPVKLKNETVGVLQIVNKVDGHFNDSDEEHLTTFANYCGIALYIAKSDCPCCICDGTERFIVLNTGAPNFIRSLCKPCYLVMLMYRRIRHSEQRYKVALDVLSYHSGFDLVELQLLSEAKIPYEWSEMAEYYYCPWDIDEIRQLEAFLYMFRTLFGIFNIDEKENLIKPKFSEIIWRFEKKTLMRFILTVKKNYRKVPYHNWSHAFTVGQSMFCMLMNTSHEYTLIESLALFIGCFCHDLDHRGKTNEYIVKSDTALGSLYTTSTMEHHHFNMTVSILQRDEHNIFEHMNSTDYKTVLDLIKHDILATDLNRFFVNNVKVSKL--IENNEMDWKNFNHRYIFMELFMTAGDLSAMYKPWDMQLNFVKVIMQEFWDQGDVEKQEGSVPARMMDRAYNYELPAMEIGFITFICLPCYTSLDKIVSGAFPVVSGLQKNLDQWKTLKDLPKED 503 The following BLAST results are available for this feature:
BLAST of Phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30027661 ID=SMED30027661|Name=Phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=2874bpback to top protein sequence of SMED30027661-orf-1 >SMED30027661-orf-1 ID=SMED30027661-orf-1|Name=SMED30027661-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=433bp MPVKMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKback to top protein sequence of SMED30027661-orf-2 >SMED30027661-orf-2 ID=SMED30027661-orf-2|Name=SMED30027661-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=300bp MSSPFKTLSHRNLLPINYHIRLADTQYDRENGILHKSPRLCNFEHKMHSEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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