Serrate RNA effector molecule

Overview
NameSerrate RNA effector molecule
Smed IDSMED30027641
Length (bp)2330
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Serrate RNA effector molecule (SMED30027641) t-SNE clustered cells

Violin plots show distribution of expression levels for Serrate RNA effector molecule (SMED30027641) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Serrate RNA effector molecule (SMED30027641) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Serrate RNA effector molecule (SMED30027641) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027641

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30027641h1SMcG0022268 SmedASXL_005353SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30027641h1SMcG0022268 SmedASXL_005353SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
epidermisSMED30027641h1SMcG0022268 dd_Smed_v4_3660_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30027641h1SMcG0022268 dd_Smed_v4_3660_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30027641h1SMcG0022268 dd_Smed_v4_3660_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Human
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101])

HSP 1 Score: 296.975 bits (759), Expect = 2.597e-91
Identity = 165/369 (44.72%), Postives = 243/369 (65.85%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDA----------NPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPE-HPSNRPNPSRAI 1987
            PRPLHK+CS+F++NI P + R+++  L K +PG++R+AL +P PER+F RRGWVTF+RS ++K + W L   +L + +L   VN+++++R+R    +T H+ ++R D+K AAKL+   D R  LW S+             NP+L NIT++L++E S EEE  LG   SS  A         +P  I ++ D  L +VLD+L+LYLRIVHS DYY+  EY  ED +PNRCG++H RG +  P  R+S   + ++ K FE K   +L   ++L    A ++G K  E+ VEKF+T NT+E+  +KWLCPLSGKKFKGP++VRKHI NK+A++I+ VK+ V FFNN++ D +RP LPE  P+  P P++ +
Sbjct:   44 PRPLHKTCSLFMRNIAPNISRAEIISLCKRYPGFMRVALSEPQPERRFFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPLPTSLPSQNPILKNITDYLIEEVSAEEEELLG---SSGGAPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPM--PPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQIL 407
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Human
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101])

HSP 1 Score: 113.235 bits (282), Expect = 4.706e-25
Identity = 54/125 (43.20%), Postives = 82/125 (65.60%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVL 625
            +  P M  FK FL   +D++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +  +  +    + +R +VF+ L E  + D + + I+  D++ K+LD+AVI +EGGTENDLR+L
Sbjct:  144 VPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Human
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101])

HSP 1 Score: 113.235 bits (282), Expect = 4.713e-25
Identity = 54/125 (43.20%), Postives = 82/125 (65.60%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVL 625
            +  P M  FK FL   +D++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +  +  +    + +R +VF+ L E  + D + + I+  D++ K+LD+AVI +EGGTENDLR+L
Sbjct:  144 VPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Human
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101])

HSP 1 Score: 113.235 bits (282), Expect = 4.731e-25
Identity = 54/125 (43.20%), Postives = 82/125 (65.60%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVL 625
            +  P M  FK FL   +D++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +  +  +    + +R +VF+ L E  + D + + I+  D++ K+LD+AVI +EGGTENDLR+L
Sbjct:  144 VPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Human
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101])

HSP 1 Score: 113.235 bits (282), Expect = 4.738e-25
Identity = 54/125 (43.20%), Postives = 82/125 (65.60%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVL 625
            +  P M  FK FL   +D++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +  +  +    + +R +VF+ L E  + D + + I+  D++ K+LD+AVI +EGGTENDLR+L
Sbjct:  144 VPPPVMKTFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLRVFLSLMETGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Celegans
Match: E01A2.2 (Serrate RNA effector molecule homolog [Source:UniProtKB/Swiss-Prot;Acc:Q966L5])

HSP 1 Score: 298.901 bits (764), Expect = 4.164e-90
Identity = 208/608 (34.21%), Postives = 311/608 (51.15%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLR-VLEKKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEGVDPRP--------LHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDA-------------------NPLLCNITE---HLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGN--------------LLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRP 1939
            I   P+  FK FL  QED+I  EDA++KYNEYK      QL+ FF AHKDEEWF  KY PD  +      LEN+  R +VF  L E    ++ S+     +++ ++LDS V+ LE GTE++L+ VL +K+                                  +D+S     + +K  +  +G E         PK+E  PE+K  +E  A +EL    ++           +H++CSVF++NI P +   +LE L K  PG++R+AL D + ERKF RRGW TF+R  ++K + W LN  +L + DL A++N++I++R+R    + +H+ V   D+K A KL   +DK+  L+ + ++A                   NPL+  +     H V     EEEA L G   SN       G       IR + D ++ + LD L++YLRIVHS D+Y+   Y  ED +PNRCGL+H RG               L+ P     Q  +  ++  F  + E  L     +      ++G K  E+ VE FI  NT E+  +KWLCPLSGKKFKGP+++RKH+ +K+ D+++  +    FFNNY+ D +RP
Sbjct:   79 IYSGPLQTFKKFLTSQEDDISEEDAIKKYNEYKTEHRKHQLERFFRAHKDEEWFRLKYKPDDAKKLREAHLENVQKRLQVFNELKEQGQFNKFSLDFGDAEAIIRMLDSVVVKLENGTEDELKAVLAQKL----------------------------------EDES----LADIKKDENGNGTEQ--------PKEE--PEVK--QESGATEELEEGAIEDGTEKSSNKVNIHRTCSVFLRNIPPGLTYEELEGLCKKSPGFLRLALTDGIAERKFYRRGWATFKRDINIKEICWALNAHRLRETDLNAIINRDITRRVRTNNGIASHKQVAINDLKLAVKLTVLYDKKIGLFNAADEADADREMDIRMGVDLVAASTNPLIKEVKSLVPHDVLNDISEEEAELLG--VSN-------GGEAPAEKIRFERDDNILKALDLLIVYLRIVHSIDFYNHGHYAQEDSMPNRCGLIHVRGQPPSGVSITTDEDGALVVP-----QKFVNDFISGFNSRIEKGLIEKQYVSEEELEKMGKKDGEKEVEAFIQKNTVELAKDKWLCPLSGKKFKGPEFIRKHLQSKHEDKLEEARAEADFFNNYLADAQRP 622
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Celegans
Match: E01A2.2 (Serrate RNA effector molecule homolog [Source:UniProtKB/Swiss-Prot;Acc:Q966L5])

HSP 1 Score: 219.935 bits (559), Expect = 9.232e-63
Identity = 164/503 (32.60%), Postives = 253/503 (50.30%), Query Frame = 2 
Query:  566 LLDSAVILLEGGTENDLR-VLEKKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEGVDPRP--------LHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDA-------------------NPLL---CNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGN--------------LLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRP 1939
            +LDS V+ LE GTE++L+ VL +K+                                  +D+S     + +K  +  +G E         PK+E  PE+K  +E  A +EL    ++           +H++CSVF++NI P +   +LE L K  PG++R+AL D + ERKF RRGW TF+R  ++K + W LN  +L + DL A++N++I++R+R    + +H+ V   D+K A KL   +DK+  L+ + ++A                   NPL+    ++  H V     EEEA L G   SN       G       IR + D ++ + LD L++YLRIVHS D+Y+   Y  ED +PNRCGL+H RG               L+ P     Q  +  ++  F  + E  L     +      ++G K  E+ VE FI  NT E+  +KWLCPLSGKKFKGP+++RKH+ +K+ D+++  +    FFNNY+ D +RP
Sbjct:    1 MLDSVVVKLENGTEDELKAVLAQKL----------------------------------EDES----LADIKKDENGNGTEQ--------PKEE--PEVK--QESGATEELEEGAIEDGTEKSSNKVNIHRTCSVFLRNIPPGLTYEELEGLCKKSPGFLRLALTDGIAERKFYRRGWATFKRDINIKEICWALNAHRLRETDLNAIINRDITRRVRTNNGIASHKQVAINDLKLAVKLTVLYDKKIGLFNAADEADADREMDIRMGVDLVAASTNPLIKEVKSLVPHDVLNDISEEEAELLG--VSN-------GGEAPAEKIRFERDDNILKALDLLIVYLRIVHSIDFYNHGHYAQEDSMPNRCGLIHVRGQPPSGVSITTDEDGALVVP-----QKFVNDFISGFNSRIEKGLIEKQYVSEEELEKMGKKDGEKEVEAFIQKNTVELAKDKWLCPLSGKKFKGPEFIRKHLQSKHEDKLEEARAEADFFNNYLADAQRP 439
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Fly
Match: Ars2 (gene:FBgn0033062 transcript:FBtr0086020)

HSP 1 Score: 286.574 bits (732), Expect = 1.262e-83
Identity = 164/391 (41.94%), Postives = 235/391 (60.10%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESD------------------------NDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYR 2014
            PR LH++ S+F++N+ P + RS++E +   F GY+R+A+ DP+ ER++ RRGW+TF R  ++K + W LN  +L D ++GA+VN+++S+R+RP   +T H+ V+R D+K  AK+    D++  LW                           N  NP+L NIT++L++E S EEE  LG        +TG    T +   I  DE   L  VLDRLVLYLRIVHS DYY+  EY  ED +PNRCG++HARG    P  R++   +++Y+K +E K +  L     L       LG K  E  VEKF+  NT+E+  +KWLCPLSGKKFKGP+++RKHI NK+ +++D V++ VQ+FNNY+ DP+RPQLPEHP     P           YR
Sbjct:  508 PRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLG--------LTGENKDT-EGEPIERDE--QLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGP---PPVRVTNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYR 884

HSP 2 Score: 118.242 bits (295), Expect = 6.269e-27
Identity = 69/156 (44.23%), Postives = 93/156 (59.62%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHP-DYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKK-----VYRADSPERTEIKIDIKSKNDP 700
            +TQP ML  K FL+ Q++NI   + MRKY EYK  F  +QL  FF AHKDEEWF  KYHP D ++  E +R   +  R  VFM L EN  +  V V  +  D+L ++LD+ VI LEGGT+ DL+VL++K     VY   + +   +K   K+ N P
Sbjct:  150 LTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQR-GFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSP 304
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Fly
Match: Ars2 (gene:FBgn0033062 transcript:FBtr0086021)

HSP 1 Score: 286.574 bits (732), Expect = 1.262e-83
Identity = 164/391 (41.94%), Postives = 235/391 (60.10%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESD------------------------NDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYR 2014
            PR LH++ S+F++N+ P + RS++E +   F GY+R+A+ DP+ ER++ RRGW+TF R  ++K + W LN  +L D ++GA+VN+++S+R+RP   +T H+ V+R D+K  AK+    D++  LW                           N  NP+L NIT++L++E S EEE  LG        +TG    T +   I  DE   L  VLDRLVLYLRIVHS DYY+  EY  ED +PNRCG++HARG    P  R++   +++Y+K +E K +  L     L       LG K  E  VEKF+  NT+E+  +KWLCPLSGKKFKGP+++RKHI NK+ +++D V++ VQ+FNNY+ DP+RPQLPEHP     P           YR
Sbjct:  508 PRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLG--------LTGENKDT-EGEPIERDE--QLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGP---PPVRVTNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYR 884

HSP 2 Score: 118.242 bits (295), Expect = 6.269e-27
Identity = 69/156 (44.23%), Postives = 93/156 (59.62%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHP-DYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKK-----VYRADSPERTEIKIDIKSKNDP 700
            +TQP ML  K FL+ Q++NI   + MRKY EYK  F  +QL  FF AHKDEEWF  KYHP D ++  E +R   +  R  VFM L EN  +  V V  +  D+L ++LD+ VI LEGGT+ DL+VL++K     VY   + +   +K   K+ N P
Sbjct:  150 LTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQR-GFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSP 304
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Fly
Match: Ars2 (gene:FBgn0033062 transcript:FBtr0086018)

HSP 1 Score: 286.574 bits (732), Expect = 1.262e-83
Identity = 164/391 (41.94%), Postives = 235/391 (60.10%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESD------------------------NDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYR 2014
            PR LH++ S+F++N+ P + RS++E +   F GY+R+A+ DP+ ER++ RRGW+TF R  ++K + W LN  +L D ++GA+VN+++S+R+RP   +T H+ V+R D+K  AK+    D++  LW                           N  NP+L NIT++L++E S EEE  LG        +TG    T +   I  DE   L  VLDRLVLYLRIVHS DYY+  EY  ED +PNRCG++HARG    P  R++   +++Y+K +E K +  L     L       LG K  E  VEKF+  NT+E+  +KWLCPLSGKKFKGP+++RKHI NK+ +++D V++ VQ+FNNY+ DP+RPQLPEHP     P           YR
Sbjct:  508 PRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLG--------LTGENKDT-EGEPIERDE--QLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGP---PPVRVTNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYR 884

HSP 2 Score: 118.242 bits (295), Expect = 6.269e-27
Identity = 69/156 (44.23%), Postives = 93/156 (59.62%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHP-DYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKK-----VYRADSPERTEIKIDIKSKNDP 700
            +TQP ML  K FL+ Q++NI   + MRKY EYK  F  +QL  FF AHKDEEWF  KYHP D ++  E +R   +  R  VFM L EN  +  V V  +  D+L ++LD+ VI LEGGT+ DL+VL++K     VY   + +   +K   K+ N P
Sbjct:  150 LTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQR-GFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSP 304
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Fly
Match: Ars2 (gene:FBgn0033062 transcript:FBtr0310667)

HSP 1 Score: 285.804 bits (730), Expect = 1.909e-83
Identity = 164/391 (41.94%), Postives = 235/391 (60.10%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESD------------------------NDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYR 2014
            PR LH++ S+F++N+ P + RS++E +   F GY+R+A+ DP+ ER++ RRGW+TF R  ++K + W LN  +L D ++GA+VN+++S+R+RP   +T H+ V+R D+K  AK+    D++  LW                           N  NP+L NIT++L++E S EEE  LG        +TG    T +   I  DE   L  VLDRLVLYLRIVHS DYY+  EY  ED +PNRCG++HARG    P  R++   +++Y+K +E K +  L     L       LG K  E  VEKF+  NT+E+  +KWLCPLSGKKFKGP+++RKHI NK+ +++D V++ VQ+FNNY+ DP+RPQLPEHP     P           YR
Sbjct:  508 PRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLG--------LTGENKDT-EGEPIERDE--QLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGP---PPVRVTNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYR 884

HSP 2 Score: 118.242 bits (295), Expect = 6.517e-27
Identity = 66/155 (42.58%), Postives = 91/155 (58.71%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKK-----VYRADSPERTEIKIDIKSKNDP 700
            +TQP ML  K FL+ Q++NI   + MRKY EYK  F  +QL  FF AHKDEEWF  KYHP+    +  ++   +  R  VFM L EN  +  V V  +  D+L ++LD+ VI LEGGT+ DL+VL++K     VY   + +   +K   K+ N P
Sbjct:  150 LTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSP 304
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Fly
Match: Ars2 (gene:FBgn0033062 transcript:FBtr0310665)

HSP 1 Score: 285.804 bits (730), Expect = 1.968e-83
Identity = 164/391 (41.94%), Postives = 235/391 (60.10%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESD------------------------NDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYR 2014
            PR LH++ S+F++N+ P + RS++E +   F GY+R+A+ DP+ ER++ RRGW+TF R  ++K + W LN  +L D ++GA+VN+++S+R+RP   +T H+ V+R D+K  AK+    D++  LW                           N  NP+L NIT++L++E S EEE  LG        +TG    T +   I  DE   L  VLDRLVLYLRIVHS DYY+  EY  ED +PNRCG++HARG    P  R++   +++Y+K +E K +  L     L       LG K  E  VEKF+  NT+E+  +KWLCPLSGKKFKGP+++RKHI NK+ +++D V++ VQ+FNNY+ DP+RPQLPEHP     P           YR
Sbjct:  504 PRALHRTSSIFLRNLAPSITRSEIEAVCNRFSGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEGPKDDSNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLG--------LTGENKDT-EGEPIERDE--QLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGP---PPVRVTNNDVQEYIKIYESKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYR 880

HSP 2 Score: 118.242 bits (295), Expect = 6.716e-27
Identity = 66/155 (42.58%), Postives = 91/155 (58.71%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKK-----VYRADSPERTEIKIDIKSKNDP 700
            +TQP ML  K FL+ Q++NI   + MRKY EYK  F  +QL  FF AHKDEEWF  KYHP+    +  ++   +  R  VFM L EN  +  V V  +  D+L ++LD+ VI LEGGT+ DL+VL++K     VY   + +   +K   K+ N P
Sbjct:  146 LTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSP 300
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Zebrafish
Match: srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:NCBI gene;Acc:192311])

HSP 1 Score: 283.108 bits (723), Expect = 1.265e-82
Identity = 153/356 (42.98%), Postives = 230/356 (64.61%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESD----------NDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPE 1951
            PRPLH++CS+F+++I P + ++++  L + +PG++R+ L +P PER+F RR WVTF+R  ++K + W L   +L D +L   VN+++++R+R    +T H+ V+R D+K AAKL+   D R  LW                NP+L NIT++L++E S EEE  LG   S+    +  G    +P  I ++ D  L +VLDRL+ YLRIVHS DYY+  EY  ED +PNRCG++H RG +  P  R++   +  + K FE K   +    +NL    A+++G K  E+ VEKF+  NT+E+  +KWLCPLSGKKFKGP++VRKHILNK+ D+I+ VK+ V FFNN+++D +RP +PE
Sbjct:  445 PRPLHRTCSLFMRSIAPTISKAEIVALCRRYPGFMRVCLSEPQPERRFFRRCWVTFDRGVNIKEICWNLQNIRLRDCELAPGVNRDLARRVRNVNGITQHKQVLRNDIKLAAKLIHALDDREKLWSQKPREETPTLELPAQNPILKNITDYLIEEVSAEEEELLG---SAGGGDSEDGSKEGNPTEITVERDEKLVKVLDRLLFYLRIVHSIDYYNTCEYPSEDEMPNRCGIIHVRGPI--PPNRITLREVSDWQKTFEEKMGPLFSVKENLSEDEAAKMGRKDPEQEVEKFVVANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGDKIEEVKKEVVFFNNFLMDAKRPCIPE 795

HSP 2 Score: 111.694 bits (278), Expect = 1.049e-24
Identity = 54/124 (43.55%), Postives = 81/124 (65.32%), Query Frame = 2 
Query:  260 PPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEK 631
            P M  FK FL   +D++   +++++YNEYK  F  +Q+Q FF AHKDEEWF  KYHPD    ++ +    + +R  V+M+L +N + + VS+ I     + K+LD+AVI +EGG ENDLR+LE+
Sbjct:  151 PVMKTFKEFLISLDDSVDETESVKRYNEYKIDFRRQQMQDFFLAHKDEEWFRSKYHPDEAGRRKAEAHSALQNRLGVYMYLMDNNWFESVSLDIERAPQITKILDAAVIKMEGGAENDLRILEQ 274
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Zebrafish
Match: srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:NCBI gene;Acc:192311])

HSP 1 Score: 283.108 bits (723), Expect = 2.201e-82
Identity = 153/356 (42.98%), Postives = 230/356 (64.61%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESD----------NDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPE 1951
            PRPLH++CS+F+++I P + ++++  L + +PG++R+ L +P PER+F RR WVTF+R  ++K + W L   +L D +L   VN+++++R+R    +T H+ V+R D+K AAKL+   D R  LW                NP+L NIT++L++E S EEE  LG   S+    +  G    +P  I ++ D  L +VLDRL+ YLRIVHS DYY+  EY  ED +PNRCG++H RG +  P  R++   +  + K FE K   +    +NL    A+++G K  E+ VEKF+  NT+E+  +KWLCPLSGKKFKGP++VRKHILNK+ D+I+ VK+ V FFNN+++D +RP +PE
Sbjct:  463 PRPLHRTCSLFMRSIAPTISKAEIVALCRRYPGFMRVCLSEPQPERRFFRRCWVTFDRGVNIKEICWNLQNIRLRDCELAPGVNRDLARRVRNVNGITQHKQVLRNDIKLAAKLIHALDDREKLWSQKPREETPTLELPAQNPILKNITDYLIEEVSAEEEELLG---SAGGGDSEDGSKEGNPTEITVERDEKLVKVLDRLLFYLRIVHSIDYYNTCEYPSEDEMPNRCGIIHVRGPI--PPNRITLREVSDWQKTFEEKMGPLFSVKENLSEDEAAKMGRKDPEQEVEKFVVANTQELGKDKWLCPLSGKKFKGPEFVRKHILNKHGDKIEEVKKEVVFFNNFLMDAKRPCIPE 813

HSP 2 Score: 111.309 bits (277), Expect = 1.284e-24
Identity = 54/124 (43.55%), Postives = 81/124 (65.32%), Query Frame = 2 
Query:  260 PPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEK 631
            P M  FK FL   +D++   +++++YNEYK  F  +Q+Q FF AHKDEEWF  KYHPD    ++ +    + +R  V+M+L +N + + VS+ I     + K+LD+AVI +EGG ENDLR+LE+
Sbjct:  169 PVMKTFKEFLISLDDSVDETESVKRYNEYKIDFRRQQMQDFFLAHKDEEWFRSKYHPDEAGRRKAEAHSALQNRLGVYMYLMDNNWFESVSLDIERAPQITKILDAAVIKMEGGAENDLRILEQ 292
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Xenopus
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101])

HSP 1 Score: 357.451 bits (916), Expect = 1.206e-110
Identity = 217/602 (36.05%), Postives = 341/602 (56.64%), Query Frame = 2 
Query:  260 PPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLE-------KKVYRADSPERTEIKIDIKSKNDP-----SSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELP--------------AEGVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDND------ANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRP 1969
            P M  FK FL   ED++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +   + +    + +R   FM+L EN +++EV + I    ++ K+LD+AVI +EGGTE DL++L+       ++  + +    TE +  +  + +P     +   W     +S    + +    G +   R    +   ++  D       P+ ++P +    ++ P               + V PRPLHK+CS+F++NI P + ++++  L K +PG++R+AL +P PER+FLR+ +VTF+RS ++K + W +   +L + +L   VN++++ R+R    +T HR ++R D+K AA+L+   D+R  LWE +         NP+L NIT++L+DE + EEE  L    S+            +P  I ++ D  L +VLD+L+ YLRIVHS DYY+  EY  ED +P RCG++H RG L  P  R+S   + ++ K FE K   +    + L    A ++G K  E+ VEKF+T NT+E+  EKWLCPLSGKKFKGP++VRKHI NK+ ++I+ VK+ V  F       +RP LPE    RP
Sbjct:  147 PIMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILDEEEEEAKREAAKKEEARATEAEKKVTEEKEPPAKGGAGCAW----VASVLYSAVLPPQPGTRKRKRSGDSDDGSDSESDTETASPKPKAETPSQNGRAEDTPKKEEETEKQKEKQKEDPVKPRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLWEGEQGDQMVSAQNPILKNITDYLIDEVNAEEEELL---FSAGRTPETETPKEGNPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGPL--PPNRVSHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHGEKIEEVKKEVA-FQTLPDRQQRPALPEVEPLRP 738
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Xenopus
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101])

HSP 1 Score: 352.058 bits (902), Expect = 1.051e-108
Identity = 217/588 (36.90%), Postives = 339/588 (57.65%), Query Frame = 2 
Query:  260 PPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLE-------KKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTS--SGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEGVDP---RPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDND------ANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRP 1969
            P M  FK FL   ED++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +   + +    + +R   FM+L EN +++EV + I    ++ K+LD+AVI +EGGTE DL++L+       ++  + +    TE +  +  + +P + K     T    G   S  +  SG   ++  + ++     ++ +       E    +E     +   +  DP   RPLHK+CS+F++NI P + ++++  L K +PG++R+AL +P PER+FLR+ +VTF+RS ++K + W +   +L + +L   VN++++ R+R    +T HR ++R D+K AA+L+   D+R  LWE +         NP+L NIT++L+DE + EEE  L    S+            +P  I ++ D  L +VLD+L+ YLRIVHS DYY+  EY  ED +P RCG++H RG L  P  R+S   + ++ K FE K   +    + L    A ++G K  E+ VEKF+T NT+E+  EKWLCPLSGKKFKGP++VRKHI NK+ ++I+ VK+ V  F       +RP LPE    RP
Sbjct:  147 PIMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILDEEEEEAKREAAKKEEARATEAEKKVTEEKEPPAKKEPLCLTEQRCGQLPSYPQGDSGATGANVFACQQ-----ILTIRPYWFPAEDTPKKEEETEKQKEKQKEDPVKPRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLWEGEQGDQMVSAQNPILKNITDYLIDEVNAEEEELL---FSAGRTPETETPKEGNPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGPL--PPNRVSHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHGEKIEEVKKEVA-FQTLPDRQQRPALPEVEPLRP 723
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Xenopus
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101])

HSP 1 Score: 274.633 bits (701), Expect = 3.206e-80
Identity = 152/360 (42.22%), Postives = 227/360 (63.06%), Query Frame = 2 
Query:  908 VDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDND------ANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRP 1969
            V PRPLHK+CS+F++NI P + ++++  L K +PG++R+AL +P PER+FLR+ +VTF+RS ++K + W +   +L + +L   VN++++ R+R    +T HR ++R D+K AA+L+   D+R  LWE +         NP+L NIT++L+DE + EEE  L     +    T + G   +P  I ++ D  L +VLD+L+ YLRIVHS DYY+  EY  ED +P RCG++H RG L  P  R+S   + ++ K FE K   +    + L    A ++G K  E+ VEKF+T NT+E+  EKWLCPLSGKKFKGP++VRKHI NK+ ++I+ VK+ V F       P R Q P  P  +P
Sbjct:  390 VKPRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLWEGEQGDQMVSAQNPILKNITDYLIDEVNAEEEELLFSAGRTPETETPKEG---NPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGPL--PPNRVSHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHGEKIEEVKKEVAFQTL----PDRQQRPALPEVKP 740

HSP 2 Score: 110.923 bits (276), Expect = 1.900e-24
Identity = 54/123 (43.90%), Postives = 81/123 (65.85%), Query Frame = 2 
Query:  260 PPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLE 628
            P M  FK FL   ED++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +   + +    + +R   FM+L EN +++EV + I    ++ K+LD+AVI +EGGTE DL++L+
Sbjct:  147 PIMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILD 269
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Xenopus
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101])

HSP 1 Score: 275.404 bits (703), Expect = 5.850e-80
Identity = 152/360 (42.22%), Postives = 226/360 (62.78%), Query Frame = 2 
Query:  908 VDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDND------ANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRP 1969
            V PRPLHK+CS+F++NI P + ++++  L K +PG++R+AL +P PER+FLR+ +VTF+RS ++K + W +   +L + +L   VN++++ R+R    +T HR ++R D+K AA+L+   D+R  LWE +         NP+L NIT++L+DE + EEE  L    S+            +P  I ++ D  L +VLD+L+ YLRIVHS DYY+  EY  ED +P RCG++H RG L  P  R+S   + ++ K FE K   +    + L    A ++G K  E+ VEKF+T NT+E+  EKWLCPLSGKKFKGP++VRKHI NK+ ++I+ VK+ V  F       +RP LPE    RP
Sbjct:  406 VKPRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLWEGEQGDQMVSAQNPILKNITDYLIDEVNAEEEELL---FSAGRTPETETPKEGNPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGPL--PPNRVSHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHGEKIEEVKKEVA-FQTLPDRQQRPALPEVEPLRP 759

HSP 2 Score: 111.309 bits (277), Expect = 1.640e-24
Identity = 54/123 (43.90%), Postives = 81/123 (65.85%), Query Frame = 2 
Query:  260 PPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLE 628
            P M  FK FL   ED++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +   + +    + +R   FM+L EN +++EV + I    ++ K+LD+AVI +EGGTE DL++L+
Sbjct:  147 PIMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILD 269
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Xenopus
Match: SRRT (serrate, RNA effector molecule [Source:HGNC Symbol;Acc:HGNC:24101])

HSP 1 Score: 274.633 bits (701), Expect = 1.013e-79
Identity = 152/360 (42.22%), Postives = 227/360 (63.06%), Query Frame = 2 
Query:  908 VDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESD------NDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRP 1969
            V PRPLHK+CS+F++NI P + ++++  L K +PG++R+AL +P PER+FLR+ +VTF+RS ++K + W +   +L + +L   VN++++ R+R    +T HR ++R D+K AA+L+   D+R  LWE +      +  NP+L NIT++L+DE + EEE  L    S+            +P  I ++ D  L +VLD+L+ YLRIVHS DYY+  EY  ED +P RCG++H RG L  P  R+S   + ++ K FE K   +    + L    A ++G K  E+ VEKF+T NT+E+  EKWLCPLSGKKFKGP++VRKHI NK+ ++I+ VK+ V  F       +RP LPE    RP
Sbjct:  385 VKPRPLHKTCSIFMRNIPPNISKAEITALCKRYPGFMRVALSEPQPERRFLRKAYVTFDRSVNIKEICWSVQNIRLRECELSPGVNRDLTYRVRNINGITMHRPIVRNDIKLAARLIHALDERALLWEGEPPLHMVSAQNPILKNITDYLIDEVNAEEEELL---FSAGRTPETETPKEGNPTEISVERDEKLIKVLDKLLFYLRIVHSVDYYNTCEYPNEDEMPTRCGMMHVRGPL--PPNRVSHGEVAEWQKTFEEKLSPLFAVRETLSEEEAVKMGKKDPEQEVEKFVTANTQELGKEKWLCPLSGKKFKGPEFVRKHIFNKHGEKIEEVKKEVA-FQTLPDRQQRPALPEVEPLRP 738

HSP 2 Score: 110.923 bits (276), Expect = 2.083e-24
Identity = 54/123 (43.90%), Postives = 81/123 (65.85%), Query Frame = 2 
Query:  260 PPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLE 628
            P M  FK FL   ED++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +   + +    + +R   FM+L EN +++EV + I    ++ K+LD+AVI +EGGTE DL++L+
Sbjct:  147 PIMKTFKEFLLSLEDSVDETEAVKRYNDYKIDFRRQQMQEFFLAHKDEEWFRSKYHPDEVGKHKQESQAALRNRLSAFMYLMENSWLNEVQLDIAQSTAIIKVLDAAVIKMEGGTEIDLKILD 269
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Mouse
Match: Srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527])

HSP 1 Score: 255.373 bits (651), Expect = 1.045e-75
Identity = 156/369 (42.28%), Postives = 232/369 (62.87%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDA----------NPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPE-HPSNRPNPSRAI 1987
            PRPLHK+CS+F++NI P + R+++  +        R+ + +P   R F RRGWVTF+RS ++K + W L   +L + +L   VN+++++R+R    +T H+ ++R D+K AAKL+   D R  LW S+             NP+L NIT++L++E S EEE  LG   SS            +P  I ++ D  L +VLD+L+LYLRIVHS DYY+  EY  ED +PNRCG++H RG +  P  R+S   + ++ K FE K   +L   ++L    A ++G K  E+ VEKF+T NT+E+  +KWLCPLSGKKFKGP++VRKHI NK+A++I+ VK+ V FFNN++ D +RP LPE  P+  P P++ +
Sbjct:   57 PRPLHKTCSLFMRNIAPNISRAEIISVSGDIGLRGRVGV-NPRSFR-FFRRGWVTFDRSVNIKEICWNLQNIRLRECELSPGVNRDLTRRVRNINGITQHKQIVRNDIKLAAKLIHTLDDRTQLWASEPGTPPVPTSLPSQNPILKNITDYLIEEVSAEEEELLG---SSGGPPPEEPPKEGNPAEINVERDEKLIKVLDKLLLYLRIVHSLDYYNTCEYPNEDEMPNRCGIIHVRGPM--PPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQIL 418
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Mouse
Match: Srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527])

HSP 1 Score: 163.31 bits (412), Expect = 7.910e-45
Identity = 77/160 (48.12%), Postives = 111/160 (69.38%), Query Frame = 2 
Query: 1511 HSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPE-HPSNRPNPSRAI 1987
            HS DYY+  EY  ED +PNRCG++H RG +  P  R+S   + ++ K FE K   +L   ++L    A ++G K  E+ VEKF+T NT+E+  +KWLCPLSGKKFKGP++VRKHI NK+A++I+ VK+ V FFNN++ D +RP LPE  P+  P P++++
Sbjct:   42 HSLDYYNTCEYPNEDEMPNRCGIIHVRGPM--PPNRISHGEVLEWQKTFEEKLTPLLSVRESLSEEEAQKMGRKDPEQEVEKFVTSNTQELGKDKWLCPLSGKKFKGPEFVRKHIFNKHAEKIEEVKKEVAFFNNFLTDAKRPALPEIKPAQPPGPAQSL 199
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Mouse
Match: Srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527])

HSP 1 Score: 113.62 bits (283), Expect = 4.059e-26
Identity = 56/129 (43.41%), Postives = 86/129 (66.67%), Query Frame = 2 
Query:  242 INYITQPPML-LFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVL 625
            I+    PP++  FK FL   +D++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +  +  +    + +R KVF+ L E+ + D + + I+  D++ K+LD+AVI +EGGTENDLR+L
Sbjct:  140 IDLGVPPPIMKSFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLKVFLSLMESGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Mouse
Match: Srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527])

HSP 1 Score: 113.235 bits (282), Expect = 3.002e-25
Identity = 55/125 (44.00%), Postives = 83/125 (66.40%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVL 625
            +  P M  FK FL   +D++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +  +  +    + +R KVF+ L E+ + D + + I+  D++ K+LD+AVI +EGGTENDLR+L
Sbjct:  144 VPPPIMKSFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLKVFLSLMESGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Mouse
Match: Srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:MGI Symbol;Acc:MGI:1933527])

HSP 1 Score: 113.235 bits (282), Expect = 3.083e-25
Identity = 55/125 (44.00%), Postives = 83/125 (66.40%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVL 625
            +  P M  FK FL   +D++   +A+++YN+YK  F  +Q+Q FF AHKDEEWF  KYHPD +  +  +    + +R KVF+ L E+ + D + + I+  D++ K+LD+AVI +EGGTENDLR+L
Sbjct:  144 VPPPIMKSFKEFLLSLDDSVDETEAVKRYNDYKLDFRRQQMQDFFLAHKDEEWFRSKYHPDEVGKRRQEARGALQNRLKVFLSLMESGWFDNLLLDIDKADAIVKMLDAAVIKMEGGTENDLRIL 268
[Close]
BLAST of Serrate RNA effector molecule vs. UniProt/SwissProt
Match: sp|A8XEG9|SRRT_CAEBR (Serrate RNA effector molecule homolog OS=Caenorhabditis briggsae OX=6238 GN=CBG12064 PE=3 SV=1)

HSP 1 Score: 305.449 bits (781), Expect = 1.735e-91
Identity = 212/605 (35.04%), Postives = 320/605 (52.89%), Query Frame = 2 
Query:  245 NYITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFK--RLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLR-VLEKKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEGVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLW----ESDND---------------ANPLLCNITEHLVDEGSY----EEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHAR--------------GNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRP 1939
            N I   P+L FK FL  QED+I  EDA++KYNEYK      QL  FF AHKDEEWF  KY P+  EAK+ K  +LEN+  R ++F  L E    D+ ++     +++ ++LDS V+ LE G+E+DL+ VL +K+                                      D E  + VK  ++D+      E V D  K E+  E    +E  A D+   +  +   +HK+CSVF++NI P +   +LE   K +PG++R+AL D + ER+F RRGW TF+R  ++K + W LN  +L + DL A++N++I++R+R    V  H+ V   D+K A KL A +DK+  L+    ES++D                NPL+  I + +V + +     EEEA L       L ++  G S +D   +R + D  + + LD L++YLRIVHS D+Y+   Y  ED +PNRCGL+H R              G+L+ P     Q  +  ++  F  + +  L     +      ++G K  E+ VE FI  NT E+  +KWLCPLSGKKFKGP+++RKH+ +K+ D+++  +    FFNNY+ D +RP
Sbjct:   81 NSIYSGPLLPFKRFLTNQEDDISEEDAIKKYNEYKNEHRKFQLDRFFRAHKDEEWFRLKYKPE--EAKKVKEVQLENVQKRLQIFNELKEQGQFDKFTLDFEDAEAILRMLDSVVVKLENGSEDDLKAVLAQKL--------------------------------------DDESLADVKKENKDAA-----EKVEDQVKDEVKEEPNEEQEEGAIDDETDKASNKVNIHKTCSVFLRNIPPGLTYEELESTCKKYPGFLRLALTDGIAERRFYRRGWATFKRDVNIKEICWGLNAHRLRETDLNAIINRDITRRVRTNNGVAAHKQVALNDLKLAVKLTALYDKKLGLFNAADESESDREKDIRMGVDLVAASTNPLVKEI-KSIVPKDTLNDISEEEAEL-------LGVSNGGDSQSD--KVRYERDDTILKALDLLIIYLRIVHSIDFYNHGHYAQEDSMPNRCGLIHVRGQPPSGASINTDENGDLIVP-----QKFINDFISGFNSRIDKGLIEKQYVSEEDMEKMGKKDGEKEVEAFIAINTVELAKDKWLCPLSGKKFKGPEFIRKHLQSKHEDKLEEARAEADFFNNYLADAQRP 625
[Close]
BLAST of Serrate RNA effector molecule vs. UniProt/SwissProt
Match: sp|Q966L5|SRRT_CAEEL (Serrate RNA effector molecule homolog OS=Caenorhabditis elegans OX=6239 GN=E01A2.2 PE=3 SV=1)

HSP 1 Score: 298.901 bits (764), Expect = 5.297e-89
Identity = 208/608 (34.21%), Postives = 311/608 (51.15%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLR-VLEKKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEGVDPRP--------LHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDA-------------------NPLLCNITE---HLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGN--------------LLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRP 1939
            I   P+  FK FL  QED+I  EDA++KYNEYK      QL+ FF AHKDEEWF  KY PD  +      LEN+  R +VF  L E    ++ S+     +++ ++LDS V+ LE GTE++L+ VL +K+                                  +D+S     + +K  +  +G E         PK+E  PE+K  +E  A +EL    ++           +H++CSVF++NI P +   +LE L K  PG++R+AL D + ERKF RRGW TF+R  ++K + W LN  +L + DL A++N++I++R+R    + +H+ V   D+K A KL   +DK+  L+ + ++A                   NPL+  +     H V     EEEA L G   SN       G       IR + D ++ + LD L++YLRIVHS D+Y+   Y  ED +PNRCGL+H RG               L+ P     Q  +  ++  F  + E  L     +      ++G K  E+ VE FI  NT E+  +KWLCPLSGKKFKGP+++RKH+ +K+ D+++  +    FFNNY+ D +RP
Sbjct:   79 IYSGPLQTFKKFLTSQEDDISEEDAIKKYNEYKTEHRKHQLERFFRAHKDEEWFRLKYKPDDAKKLREAHLENVQKRLQVFNELKEQGQFNKFSLDFGDAEAIIRMLDSVVVKLENGTEDELKAVLAQKL----------------------------------EDES----LADIKKDENGNGTEQ--------PKEE--PEVK--QESGATEELEEGAIEDGTEKSSNKVNIHRTCSVFLRNIPPGLTYEELEGLCKKSPGFLRLALTDGIAERKFYRRGWATFKRDINIKEICWALNAHRLRETDLNAIINRDITRRVRTNNGIASHKQVAINDLKLAVKLTVLYDKKIGLFNAADEADADREMDIRMGVDLVAASTNPLIKEVKSLVPHDVLNDISEEEAELLG--VSN-------GGEAPAEKIRFERDDNILKALDLLIVYLRIVHSIDFYNHGHYAQEDSMPNRCGLIHVRGQPPSGVSITTDEDGALVVP-----QKFVNDFISGFNSRIEKGLIEKQYVSEEELEKMGKKDGEKEVEAFIQKNTVELAKDKWLCPLSGKKFKGPEFIRKHLQSKHEDKLEEARAEADFFNNYLADAQRP 622
[Close]
BLAST of Serrate RNA effector molecule vs. UniProt/SwissProt
Match: sp|Q17FR9|SRRT_AEDAE (Serrate RNA effector molecule homolog OS=Aedes aegypti OX=7159 GN=Ars2 PE=3 SV=1)

HSP 1 Score: 298.901 bits (764), Expect = 3.520e-87
Identity = 156/366 (42.62%), Postives = 237/366 (64.75%), Query Frame = 2 
Query:  905 GVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDND-------------ANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSN 1963
            G  PR LH++ S+F++N+ P + ++++E + K + G++R+A+ DP+ ER++ RRGWVTF R  ++K + W LN  +L D +LGA+VNK++S+R+RP   +T H+ ++R D+K  AK+    D +  LW+   D              NP+L NIT++L++E S EE+  LG  +S+  A       +ND   +  D    L  VLD+L+LYLR+VHS D+Y+  EY  ED +PNRCG++HARG    P  +++   +++Y++ FE K    L    +L+     +LG K  E  VEKFI  NT+E+  +KWLCPLSGKKFKGPD+VRKHI NK+ +++D V++ V++FNNY+ D +RPQLPEHP N
Sbjct:  505 GNSPRALHRTSSIFLRNLAPSITKAEVEAMCKRYNGFLRVAIADPLLERRWFRRGWVTFRRDVNIKEICWNLNNIRLRDCELGAIVNKDLSRRVRPVNGLTCHKTIVRSDIKLCAKIAHNLDDKVGLWKEQEDNGEKNGESFGLQSKNPVLQNITDYLIEEASAEEDELLG--LSTEAA-----KKSNDGELVERD--TQLIEVLDKLILYLRVVHSIDFYNHCEYPYEDEMPNRCGIIHARGPP--PQNKVTSNEIQEYIRTFEGKMGSFLARAVDLEEEEMKKLGAKDAEAEVEKFIQANTQELAKDKWLCPLSGKKFKGPDFVRKHIFNKHNEKVDEVRKEVEYFNNYLKDTKRPQLPEHPGN 859

HSP 2 Score: 110.153 bits (274), Expect = 1.985e-23
Identity = 57/127 (44.88%), Postives = 83/127 (65.35%), Query Frame = 2 
Query:  254 TQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKK 634
            TQP M+  K FL  Q+D+I   +A++KYN+YK  F  +QL  FF AHKDEEWF  KYHP+    ++ ++   +  R  VF+ L ++  + +VSV  +  D L +LLD+ VI LEGGT+ DL+VL++K
Sbjct:  133 TQPCMMTLKQFLATQDDSISDSEAIQKYNDYKLEFKRQQLNEFFVAHKDEEWFKMKYHPEESLKRKEEQFGFLKRRCDVFVELLDHGDISKVSVDTSNTDPLLRLLDTVVIKLEGGTDEDLKVLDEK 259
[Close]
BLAST of Serrate RNA effector molecule vs. UniProt/SwissProt
Match: sp|B4NYV0|SRRT_DROYA (Serrate RNA effector molecule homolog OS=Drosophila yakuba OX=7245 GN=Ars2 PE=3 SV=1)

HSP 1 Score: 293.508 bits (750), Expect = 4.115e-85
Identity = 164/391 (41.94%), Postives = 236/391 (60.36%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLW--------------ESD----------NDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYR 2014
            PR LH++ S+F++N+ P + R+++E +   F GY+R+A+ DP+ ER++ RRGW+TF R  ++K + W LN  +L D ++GA+VN+++S+R+RP   +T H+ V+R D+K  AK+    D+R  LW              ES           N  NP+L NIT++L++E S EE+  LG        +TG    T +   I  DE   L  VLDRLVLYLRIVHS DYY+  EY  ED +PNRCG++HARG       R++   +++Y+K +E K +  L     L       LG K  E  VEKF+  NT+E+  +KWLCPLSGKKFKGP+++RKHI NK+ +++D V++ VQ+FNNY+ DP+RPQLPEHP     P           YR
Sbjct:  509 PRALHRTSSIFLRNLAPSITRAEIEAVCNRFTGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGLTAHKQVVRSDIKLCAKIALNLDERFRLWAEVPTDDSNSARADESSENGSGSTYGFNSKNPVLQNITDYLIEEASAEEDELLG--------LTGENKDT-EGEAIERDE--QLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGPAPV---RVTNNDVQEYIKTYESKLQQFLTKTVLLSDEEIKDLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHDEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYR 885

HSP 2 Score: 115.546 bits (288), Expect = 4.353e-25
Identity = 62/129 (48.06%), Postives = 83/129 (64.34%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHP-DYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKK 634
            +TQP ML  K FL+ Q++NI   + MRKY EYK  F  +QL  FF AHKDEEWF  KYHP D ++  E +R   +  R  VF+ L EN  +  V V  +  D+L ++LD+ VI LEGGT+ DL+VL++K
Sbjct:  151 LTQPAMLNLKQFLDTQDENISDSEVMRKYTEYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRSEEQR-GFLQRRTDVFVELLENGTIGSVKVDSSQGDALIRVLDTCVIKLEGGTDEDLKVLDEK 278
[Close]
BLAST of Serrate RNA effector molecule vs. UniProt/SwissProt
Match: sp|B4II37|SRRT_DROSE (Serrate RNA effector molecule homolog OS=Drosophila sechellia OX=7238 GN=Ars2 PE=3 SV=2)

HSP 1 Score: 286.96 bits (733), Expect = 8.792e-83
Identity = 166/391 (42.46%), Postives = 237/391 (60.61%), Query Frame = 2 
Query:  914 PRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLW--------------ESD----------NDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYR 2014
            PR LH++ S+F++N+ P + RS++E +   F GY+R+A+ DP+ ER++ RRGW+TF R  ++K + W LN  +L D ++GA+VN+++S+R+RP   +T H+ V+R D+K  AK+    D++  LW              ES           N  NP+L NIT++L++E S EEE  LG        +TG    T +   I  DE   L  VLDRLVLYLRIVHS DYY+  EY  ED +PNRCG++HARG    P  R++   +++Y+K +E K +  L     L       LG K  E  VEKF+  NT+E+  +KWLCPLSGKKFKGP+++RKHI NK+ +++D V++ VQ+FNNY+ DP+RPQLPEHP     P           YR
Sbjct:  512 PRALHRTSSIFLRNLAPSITRSEIEAMCNRFTGYLRVAIADPLVERRWYRRGWITFMRDVNIKEICWGLNNQRLRDCEMGAIVNRDLSRRVRPANGITAHKQVVRSDIKLCAKIALNLDEKFRLWAEVPKDDPNSARANESSENGSGSTYGFNSQNPVLQNITDYLIEEASAEEEELLG--------LTGENKDT-EGEPIERDE--QLISVLDRLVLYLRIVHSVDYYNHCEYPYEDEMPNRCGIIHARGP---PPVRVTNNDVQEYIKMYETKLQQFLTKTVPLSDEEIKNLGAKDAETEVEKFVQANTQELAKDKWLCPLSGKKFKGPEFIRKHIFNKHEEKVDEVRKEVQYFNNYLRDPKRPQLPEHPGTSKRPESESARGGGGGYR 888

HSP 2 Score: 116.316 bits (290), Expect = 2.664e-25
Identity = 62/129 (48.06%), Postives = 83/129 (64.34%), Query Frame = 2 
Query:  251 ITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHP-DYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKK 634
            +TQP ML  K FL+ Q++NI   + MRKY +YK  F  +QL  FF AHKDEEWF  KYHP D ++  E +R   +  R  VFM L EN  +  V V  +  D+L ++LD+ VI LEGGT+ DL+VL++K
Sbjct:  150 LTQPAMLNLKQFLDTQDENISDSEVMRKYTDYKTDFKRQQLNEFFVAHKDEEWFKNKYHPEDSVKRNEEQR-GFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEK 277
[Close]
BLAST of Serrate RNA effector molecule vs. TrEMBL
Match: A0A0F7GYG7 (Serrate RNA effector molecule (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 434.491 bits (1116), Expect = 7.959e-141
Identity = 242/512 (47.27%), Postives = 342/512 (66.80%), Query Frame = 2 
Query:  821 VVDVPKKELSPEIKSPEEMMANDELPAEGVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDA---------NPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPN----PSRAIK----LDHANAYRRQSDPRHXXXXXXXXXXXXREANSYRKP-------------GRSDFGNRNS-----------------------------NAGALYYSRKILNYNDI 2179
            +++   K+   EI+S E +    E  +E  +PR LHK+ S+F++N+HP V RS++E LVKP+ G++R+ALQDP P+RKF RRGWVT++R+ ++K + W LN  +L D D+GA+VN+E++QRIRP   + NH+ VMR D+K A++LVAKFDKR +LW+ ++           NPLL NITE+LVDEGSYEEEA LGG+++SNL +T  G   +DP NI+++ D  LA VLDRL+LYLR VHS+DYYS TEY+IED +P+RCG+LHARG  ++ D+ L+Q  +E+Y+K FE+KAEL+L+S++ L    A +LG K ++E+V+ FI +NT+EI+ +KWLCPLSGKKFKGPD+V+KHILNK+ D+++ VKQ  +FFNNY+LDP+RPQLPEHPSNRP      S  I+     D+ N     +D R+    +N N++   +    R+P             G  D GNRN+                             N G  YY+RK+L+YND+
Sbjct:    9 IIEADDKKFEEEIESTENVEEKFEKKSEXQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYEEEALLGGNLNSNLELTVTG---SDPLNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIRNEGQFDNNNKRFGDNDSRNRNMDNNRNFSRRNDDFDNRRPNYRNDRGSSPNGGGYRDSGNRNNNFGDNRGGSNGNYYRKSSYPSRGSQSRQRNGGGSYYARKVLSYNDL 517
[Close]
BLAST of Serrate RNA effector molecule vs. TrEMBL
Match: A0A4Y7NK30 (EOG090X04A7 OS=Moina brachiata OX=675436 GN=EOG090X04A7 PE=2 SV=1)

HSP 1 Score: 424.091 bits (1089), Expect = 2.561e-133
Identity = 252/632 (39.87%), Postives = 364/632 (57.59%), Query Frame = 2 
Query:  248 YITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLE----------KKVYRADSPERTE------IKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEG-----------------------VDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDA---------------NPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSR 1981
            + TQPPM+ FK FL   +D+I  E+A++KY +YK  F  +QL  FF +HKDEEWF  KYHP+    ++ +   +ID R +VFM L E    + V++  +  + L KLLD+ VI LEGGTE DL+VLE          K   +   PE+ E      +K D  + + P+S++ DD   S   +    E  S   + D DS     R+   + P+   S  I SPE    NDE   EG                         PR LH++ S+F++N+ P + + ++E + K + G++R A+ DP PER++ RRGWVTFER+ ++K + W LN  +L D +LGA+VN+++S+RIR    +T+H+ V+R D++ AAK++   D R  LW  +N                 NP+L NIT+ L++E S EEE  LG   +         G   D   I++         LDRL+ YLRIVHS D+Y+  EY  ED +PNRCG++HARG  + P  ++SQA +  Y + FE K    L+ +  L+   AS+LG+K  E  VEKF+  NT+E+  +KWLCPLSGKKFKGPD+VRKHI+NK+ ++ID V++ V++FNNY+ DP+RPQLPEHP NR   +R
Sbjct:  102 FPTQPPMMSFKAFLAAHDDSISDEEAVKKYADYKLEFRRQQLNEFFTSHKDEEWFKLKYHPEECAKRKNEHKAHIDQRVQVFMELMEQGRFNTVTIDADQSEKLVKLLDTVVIKLEGGTEADLQVLESTGIENKPTVKPAEKVTPPEQKEEGEHESLKEDDSTNDVPASVENDDAPKSPSGEKRKREYDS-ASSIDGDS-----RDQTSEAPRSPDSKPIDSPEGEKENDESKQEGEVKESEDDAKDDAKDEKKSNGDPSQPRELHRTASIFLRNLAPTITKQEVEAMCKRYQGFLRAAIADPQPERRWFRRGWVTFERNVNIKEICWNLNNIRLRDTELGAIVNRDLSRRIRTVNGITSHKQVVRNDIRLAAKIIQNLDARLGLWAEENGEKESLPNEMTFAGTSRNPVLNNITDFLIEEASAEEEELLGSSATEEGDDEAAAGLARDEELIKV---------LDRLLFYLRIVHSVDFYNHCEYPNEDEMPNRCGIMHARG--IPPSSKVSQAEVNDYCRSFEAKIASFLEPVKKLNDDEASQLGLKECEAEVEKFVAANTQELAKDKWLCPLSGKKFKGPDFVRKHIVNKHGEKIDEVRKDVEYFNNYLRDPKRPQLPEHPGNRAAGAR 716
[Close]
BLAST of Serrate RNA effector molecule vs. TrEMBL
Match: A0A4Y7M614 (EOG090X04A7 OS=Daphnia dolichocephala OX=2282166 GN=EOG090X04A7 PE=2 SV=1)

HSP 1 Score: 422.165 bits (1084), Expect = 1.282e-131
Identity = 254/638 (39.81%), Postives = 364/638 (57.05%), Query Frame = 2 
Query:  248 YITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKKVYR--ADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKAS-------------DRDSGRESDREAVVDVPKKELSP-------EIKSPEEMMANDELPAEG------------------------VDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDND------------------ANPLLCNITEHLVDEGSYEEEAYLGGDISS-NLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNR 1966
            + TQPPM+ FK FL   +D+I  E+A++KY EYK  F  +QL  FF +HKDEEWF  KYHP+  + ++ +   +I+ R K  M L    Y D+V++  +  + L KLLD+ VI LEGGTE DL+VL+    +   + P R + K   +S N     + DD        DS  E T   K+S             D DSG + + +   DV +   SP       E  SP+ +   DE  AE                         V PR LH++ S+F++N+ P + + ++E + K +PG++R A+ DP PER++ RRGWVTFER+ ++K + W LN  +L D +LGA+VN+++S+RIR    +T+H+ V R D++ AAK++   D R  LW  +ND                   NP+L NIT+ L++E S EEE  LG   S     +    G T D   IR+         LDRL+ YLRIVHS DYY+  EY  ED +PNRCG++HARG  + P  +++Q+ +  Y + FE K    L+ I  L    AS+LG+K  +  VEKF+  NT+E+  +KWLCPLSGKKFKGPD+VRKH+ NK+A+++D V++ V++FNNY+ DP+RPQLPEHP NR
Sbjct:  145 FPTQPPMMSFKAFLAAHDDSISDEEAVKKYAEYKLEFRRQQLNEFFTSHKDEEWFKLKYHPEENQKRKNEHRNHIELRVKTMMDLMGEGYFDQVTIDADQSEKLVKLLDTVVIKLEGGTELDLQVLDNPPVQPAVEKPTRNQEKTTNESDNKEEIQESDDVKEDDALADSKTEKTDDPKSSPDNKGSKRKRSGFDSDSGSDWEGKVQSDVSEAPQSPDGKLESGEASSPQAIEEADENQAEDQKDEKEKIDEDDGKVEEKKENGAPVHPRELHRTASIFLRNLAPTITKLEVEAMCKRYPGFLRAAIADPQPERRWFRRGWVTFERNVNIKEICWNLNNIRLRDTELGAIVNRDLSRRIRTVSGITSHKQVARNDIRLAAKIIQNLDARLGLWADENDNAKNPAGTEPALSFSGASRNPVLNNITDFLIEEASAEEEELLGASASEEGEEVDAAAGVTRDNELIRV---------LDRLLFYLRIVHSVDYYNHCEYPNEDEMPNRCGIMHARG--IPPSSKVTQSEINDYCRSFENKIASFLEPIKRLSDEEASKLGLKESKAEVEKFVAANTQELAKDKWLCPLSGKKFKGPDFVRKHVFNKHAEKVDEVRKDVEYFNNYLRDPKRPQLPEHPGNR 771
[Close]
BLAST of Serrate RNA effector molecule vs. TrEMBL
Match: A0A4Y7NJZ6 (EOG090X04A7 OS=Scapholeberis mucronata OX=202097 GN=EOG090X04A7 PE=2 SV=1)

HSP 1 Score: 419.083 bits (1076), Expect = 1.417e-130
Identity = 254/652 (38.96%), Postives = 370/652 (56.75%), Query Frame = 2 
Query:  203 SNHSMKEKDDNENINYITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKKV-YRADSP--ERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKA-----------SDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELP-----------------------------AEGV--DPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDA------------------NPLLCNITEHLVDEGSYEEEAYLGGDISS-NLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNR 1966
            SN+S      +    + TQPPM+ FK FL   +D+I  E+A++KY EYK  F  +QL  FF +HKDEEWF  KYHP+    ++ +   +I+SR KV M + E K +D+V++  +  + L KLLD+ VI LEGG+ENDL  LE  V   AD P  +  E    I    +P  ++ D+    S  ++   E   G  +           SD +SG + + E   + P+   SP+ K+ +  ++  E P                               GV   PR LH++ S+F++N+ P + + ++E + K +PG++R A+ DP PER++ RRGWVTFERS ++K + W LN  +L D +LGA+VN+++S+RIR    +T+H+ V+R D++ AAK++   D R  LW    D                   NP+L NIT++L++E S EEE  LG   S          G T D   I++         LDRL+ YLRIVHS DYY+  EY  ED +PNRCG++HARG  + P  +++QA +  Y + FE K    L+ I  L    AS+LG+K  +  VEKF+  NT+E+  +KWLCPLSGKKFKGPD+VRKHI NK+ ++I+ V++ V++FNNY+ DP+RPQLPEHP NR
Sbjct:  129 SNNSSYGGTSSRGEEFPTQPPMMSFKAFLAAHDDSISDEEAVKKYAEYKLEFRRQQLNEFFTSHKDEEWFKLKYHPEENLKRKNEHKAHIESRMKVLMEIMEEKRLDQVTIDADQSEKLVKLLDTIVIKLEGGSENDLHALENPVESTADKPLPKTQEPPAKISEPKEPVEVQNDENKADSATEEPKTETAVGPSSPLNGGKRKRGNSDSESGSDWEGEPKEEAPQ---SPDGKTADVPLSPSEAPEANHEDQPKEEEDGEKAQDDNDVKEKEQKGNGVPNQPRELHRTASIFLRNLAPTITKLEVEAMCKRYPGFLRAAIADPQPERRWFRRGWVTFERSVNIKEICWNLNNIRLRDTELGAIVNRDLSRRIRTVSGITSHKQVVRNDIRLAAKIIQNLDARLGLWTDGEDKSKDSMNADSTLSFSGTSRNPVLHNITDYLIEEASAEEEELLGASASEEGEEADASAGLTRDDELIKV---------LDRLLFYLRIVHSVDYYNHCEYPNEDEMPNRCGIMHARG--IPPSSKVTQAEINDYCRSFEQKIASFLEPIKRLSEEEASKLGLKESKAEVEKFVAANTQELAKDKWLCPLSGKKFKGPDFVRKHIFNKHGEKIEEVRKDVEYFNNYLHDPKRPQLPEHPGNR 766
[Close]
BLAST of Serrate RNA effector molecule vs. TrEMBL
Match: A0A4Y7M0Q0 (EOG090X04A7 OS=Daphnia barbata OX=414587 GN=EOG090X04A7 PE=2 SV=1)

HSP 1 Score: 418.313 bits (1074), Expect = 3.987e-130
Identity = 260/643 (40.44%), Postives = 369/643 (57.39%), Query Frame = 2 
Query:  248 YITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVL----------------EKKVYRADSPERTEIKIDIKSKNDP-SSLKWDDFNTSSGDDDSDVEITSGVK---ASDRDSGRESDREAVV--DVPKKELSP-------EIKSPEEMMANDELPAE----------------------GVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLW--ESDN----------------DANPLLCNITEHLVDEGSYEEEAYLGGDISS-NLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNR 1966
            + TQPPM+ FK FL   +D+I  E+A++KY EYK  F  +QL  FF +HKDEEWF  KYHP+  + ++ +   +I+ R K  M L E  Y D+V++  +  + L KLLD+ VI LEGGTE DL+VL                EK    +D+ E  EI+     K D   +LK    +  + D  S V    G +     D DSG + +RE  V  DV +   SP       E  SP+ +   DE  A+                       V PR LH++ S+F++N+ P + + ++E + K +PG++R A+ DP PER++ RRGWVTFER+ ++K + W LN  +L D +LGA+VN+++S+RIR    +T+H+ V R D++ AAK++   D R  LW  ESDN                  NP+L NIT+ L++E S EEE  LG   S     +    G T D   IR+         LDRL+ YLRIVHS DYY+  EY  ED +PNRCG++HARG  + P  +++Q+ +  Y + FE K    L+ I  L    AS+LG+K  +  VEKF+  NT+E+  +KWLCPLSGKKFKGPD+VRKH+ NK+A+++D V++ V++FNNY+ DP+RPQLPEHP NR
Sbjct:  145 FPTQPPMMSFKAFLAAHDDSISDEEAVKKYAEYKLEFRRQQLNEFFTSHKDEEWFKLKYHPEENQKRKNEHRNHIELRVKTMMDLMEEGYFDKVTIDADQSEKLVKLLDTVVIKLEGGTELDLQVLDNPPVQPAVEKPSKSQEKATNESDTKEAEEIQESDDVKEDGMGNLK----SEKAEDPKSAVNNKGGKRKRSGFDSDSGSDWEREGKVQSDVSEAPQSPDGKPESGEASSPQALEETDETHAKLDEKEKMDECDGKVEEKKENGAPVQPRELHRTASIFLRNLAPTITKLEVEAMCKRYPGFLRAAIADPQPERRWFRRGWVTFERNVNIKEICWNLNNIRLRDTELGAIVNRDLSRRIRTVSGITSHKQVARNDIRLAAKIIQNLDARLGLWADESDNAKNPTGTEPALSFSGASRNPVLNNITDFLIEEASAEEEELLGASASEEGEEVDAAAGLTRDNELIRV---------LDRLLFYLRIVHSVDYYNHCEYPNEDEMPNRCGIMHARG--IPPSSKVTQSEINDYCRSFENKIASFLEPIKRLSDEEASKLGLKESKAEVEKFVAANTQELAKDKWLCPLSGKKFKGPDFVRKHVFNKHAEKVDEVRKDVEYFNNYLRDPKRPQLPEHPGNR 772
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Cavefish
Match: srrt (serrate RNA effector molecule homolog (Arabidopsis) [Source:NCBI gene;Acc:192311])

HSP 1 Score: 68.9366 bits (167), Expect = 1.347e-11
Identity = 63/209 (30.14%), Postives = 95/209 (45.45%), Query Frame = 2 
Query:  260 PPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLE-------------------------GGT------ENDLRVLEKKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRD 793
            P M  FK FL   +D++   +++++YNEYK  F  +Q+Q FF AHKDEEWF  KYHPD    ++      + +R  VFM L EN + D VS+ I+    + K+LD+AVI +E                         GGT       ++ R  E +   +   E  ++K    ++  P   K           DS+ E ++    SD D
Sbjct:  151 PVMKSFKEFLLSLDDSVDETESVKRYNEYKIEFRRQQMQDFFLAHKDEEWFRSKYHPDESSKRKADAHAALQNRLNVFMDLMENSWFDSVSMDIDRAPQILKILDAAVIKMEGGTENDMRILELPAEEEEERERLSSGGTPIEPAKRDENRPPEGERKPSTEKEEKKLKRSPPAEQPPEPKKMSKKRKRKHSGDSEDEASASESESDSD 359
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010621.1 (pep scaffold:Pmarinus_7.0:GL476849:23359:42927:-1 gene:ENSPMAG00000009614.1 transcript:ENSPMAT00000010621.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 351.288 bits (900), Expect = 3.634e-109
Identity = 228/609 (37.44%), Postives = 354/609 (58.13%), Query Frame = 2 
Query:  260 PPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDS--AVILLEGGTENDLRVLEK-----KVYR--ADSPERTEI--KIDIKSKNDPSSLKW------------DDFNTSSGDDDSDVEITSGVKASD--RDSGRESDREAVVDVPKKELSPEIKSPEEMM-------ANDELPAEGVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWES-----DND-------ANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKG-PDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPE 1951
            P M  FK FL    +++   +A+R+YN YK  F  +QL  FF AHKDEEWF  KYHP+    ++ +    +  R K F +L E  + + +S+ I+  + + ++LD+  AVI +EGGT+ DL+ +++     KV     DS + +E+  K+   SK    S K              D+N  S       +   G  A+   RD+G  S  E+ +D  K     E ++ E+ +         D +PA+   PR LH++CS+F++NI P + +S++  + K +PG+VR+AL DP  ER+F RRGWVTFERS ++K + W L   +L + +L  VVN+++++R+R  Q +T H+ V+R D++ AAKL+   D++  LW +     D D        NP+L NIT++L++E S EE+  LG       AITG     +  +++ ++ D  L +VLDRLVLYLRIVHS DYY+A EY+ ED +PNRCG++H RG L  P  R +   + +Y +  E +   +L++ D      A ++G K  E+ VEK++  NT+E+  +KW+CP SGKKFK   +++RKHI NK+AD++  V++ V FFNNY++D +RP  PE
Sbjct:  136 PIMKTFKEFLLSIAESVDETEAVRRYNNYKIEFRRQQLHEFFMAHKDEEWFRVKYHPEESAKRKHEAASALQHRLKAFTFLLEGGWFNSISLDIDKSEQIIRVLDAGAAVIKMEGGTDLDLQTVDQPEDDGKVENDGKDSRKLSEVDKKMSESSKEVADSGKQKKMKSMSVMVDRTDWNCDSLKSRGSRKRKRGGSAASPGRDAGNVSGSESDLDGKKGPGDGEKQAGEDGLEKESLRKGEDGVPAK---PRALHRTCSLFMRNIAPNIPKSEIVAIFKRYPGFVRVALSDPQIERRFYRRGWVTFERSVNIKEICWSLQNIRLRECELSPVVNRDLARRVRGVQGITQHKPVVRNDIRLAAKLIQALDQKAQLWSATQPIKDTDILAPFSSQNPILKNITDYLIEEVSAEEDELLGN------AITGSDEPKDSTSDVPLERDGKLLQVLDRLVLYLRIVHSVDYYNACEYQNEDEMPNRCGMIHVRGPL--PTNRATHNEVTEYERQQEERLAPLLNARDTPTPEEAIKMGKKDPEQEVEKYVQGNTQEVGKDKWVCPFSGKKFKEIMEFLRKHIFNKHADKLGEVQREVGFFNNYLMDLKRPGPPE 733
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001670.1 (pep scaffold:Pmarinus_7.0:GL480784:6169:22985:1 gene:ENSPMAG00000001502.1 transcript:ENSPMAT00000001670.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 173.326 bits (438), Expect = 2.029e-46
Identity = 129/432 (29.86%), Postives = 213/432 (49.31%), Query Frame = 2 
Query:  266 MLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLD---SAVILLEGGTENDLRVLEKKVYR----------------ADSPERTEIKIDI-------------KSKNDPSSLKWDDFNTSSGD-------DDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKS---------PEEMM-------------ANDELPAE--GVDPRP--LHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWE---------SDNDANPLLCNITEHL 1339
            M  FK FL   +D +   +A++ Y+EYK+ F  +Q+Q FF AHK EEWF  +YHPD  E +    + +   R  VF  L ++K++D V++ ++  D +   LD   +A +L+EGGT  DL+ LE++                      PE   ++                KSK DP     ++    S D       ++   E   G+K   ++  +   ++ + +  K+EL  E K          P+E +                E PAE  G+ PRP   H++ S+F++NI P + ++++  L + FPG++R+AL +P PER F RRGWVTF    +++++ W L   KL + +L  VVN+++++R+R    V+ H  V R  ++ A KLV   D+R  LWE         + + ANPLL  ++++L
Sbjct:  142 MKSFKEFLVTLDDAVEETEAVKLYSEYKQEFQQQQMQDFFLAHKGEEWFRTRYHPDEREKRRRDIIASARHRVAVFCMLKQHKWLDNVTLDLDKTDQIAHFLDAARTASMLMEGGTAEDLKALEEREESKEECSEKPEEVPKEETTKGPEEEPMEESTEELKKESNDEPKEKSKEDPKEESKEELKAESKDGLKEESMEELKAESKDGLKEESKEELKAESKDGLKEESKEELKVESKDGLKEESKEDPKEELKEESKGESKEESKTAGEKPAEEQGLLPRPRNFHRNMSIFLRNIAPYISKAEIVSLCRRFPGFMRVALSEPQPERGFYRRGWVTFSGHVNIQDICWNLQNVKLRECELSPVVNRDLARRMRIVSGVSLHATVARNHLRLALKLVHALDRRAKLWEYTEGTTIPGTSDGANPLLGGLSKYL 573
[Close]
BLAST of Serrate RNA effector molecule vs. Ensembl Nematostella
Match: EDO46264 (Ars2/serrate-like protein; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQB5])

HSP 1 Score: 144.436 bits (363), Expect = 1.977e-35
Identity = 68/148 (45.95%), Postives = 102/148 (68.92%), Query Frame = 2 
Query: 1511 HSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQ-RLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPE 1951
            HS DYY+  +Y  ED +PNRCG++H RG +  P++  L++AH  ++ K+ + K EL L   + +      +LG +  E  +EKF+  NT+E+  +KWLCPLSGKKF+GP++VRKHI NK+AD+++ V+  V+FFN +I DP+RP  PE
Sbjct:  923 HSMDYYNCGDYPHEDEMPNRCGIMHVRGPV--PEKATLAEAH--EWQKNTKQKLELFLQEKETVPDEEILKLGKRDPESEIEKFVEANTQELAKDKWLCPLSGKKFRGPEFVRKHIFNKHADQVEEVRMEVEFFNRFIADPKRPANPE 1066

HSP 2 Score: 136.346 bits (342), Expect = 6.267e-33
Identity = 58/145 (40.00%), Postives = 97/145 (66.90%), Query Frame = 2 
Query:  869 EEMMANDELPAEGVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDND 1303
            EE MA++        PRPLHK+ S+F++NI P + ++ +    K FPG++R+AL DP P+R+F RRGW+TF+RS D+K + W+ N  ++ + +L  V+N+++S+RIRP   +T  + V+R+ +K AA L+   DK+  ++E D +
Sbjct:  678 EEGMASEGKELVPAGPRPLHKTYSLFMRNIPPSISKADIAAACKRFPGFLRVALSDPSPDRRFYRRGWITFDRSVDIKQINWDFNNIRIKEAELNPVINRDLSRRIRPVNGITQAKQVVRESIKLAADLIRVLDKKSAVYEKDQE 822

HSP 3 Score: 96.6709 bits (239), Expect = 1.624e-20
Identity = 50/158 (31.65%), Postives = 86/158 (54.43%), Query Frame = 2 
Query:  188 LKRQKSNHSMKEKDDNENINYITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKKVYRADSPER 661
            + + +     +++ D  ++     P M   K FL  Q+DNI   +A+ KY  YK  F   QL  FF+ HKDEEWF  +YHP     ++ +   ++  R   F+ L E +   ++ + +++ D++ K LD+ VI LEGG++ DL +L++    + SP+R
Sbjct:  128 MGQMQMGQDARQRSDGPSLETPPGPVMQTLKQFLATQDDNIDDMEAICKYQAYKLDFKKTQLNDFFQQHKDEEWFRMRYHPREAAQRQKELQRSVRCRLNCFLELMEMELSKDLRLEVDHSDAIVKFLDAVVIKLEGGSDEDLAILDRSP--SPSPDR 283
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BLAST of Serrate RNA effector molecule vs. Ensembl Medaka
Match: srrt (serrate, RNA effector molecule [Source:NCBI gene;Acc:101166978])

HSP 1 Score: 108.227 bits (269), Expect = 9.271e-24
Identity = 54/123 (43.90%), Postives = 79/123 (64.23%), Query Frame = 2 
Query:  260 PPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLE 628
            P M  FK FL   +D++   +A+++YNEYK  F  +Q+Q FF AHKDEEWF  KYHPD     + +    + +R  VF +L EN + D VS+ I     + ++LD+AVI +EGGT++DLR+L+
Sbjct:  145 PIMKSFKEFLLSLDDSVDETEAVKRYNEYKVDFRRQQMQDFFLAHKDEEWFRSKYHPDEASRLKAEARSALHNRLNVFTFLMENGWFDHVSLDIEQSPVIIRVLDAAVIKMEGGTDHDLRILD 267
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BLAST of Serrate RNA effector molecule vs. Planmine SMEST
Match: SMESG000023055.1 (SMESG000023055.1)

HSP 1 Score: 1390.17 bits (3597), Expect = 0.000e+0
Identity = 708/709 (99.86%), Postives = 708/709 (99.86%), Query Frame = 2 
Query:   65 MSDSASDYGGWGKNEDNRGISNPKTVTKRSHPNDSLSDELSLKRQKSNHSMKEKDDNENINYITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEGVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYRRQSDPRHXXXXXXXXXXXXREANSYRKPGRSDFGNRNSNAGALYYSRKILNYNDISVAD 2191
            MSDSASDYGGWGKNEDNRGISNPKTVTKRSHPNDSLSDELSLKRQKSNHSMKEKDDNENINYITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFE HKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEGVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEDLDLARVLDRLVLYLRIVHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYRRQSDPRHNGNYSNNNYNNNREANSYRKPGRSDFGNRNSNAGALYYSRKILNYNDISVAD
Sbjct:    1 MSDSASDYGGWGKNEDNRGISNPKTVTKRSHPNDSLSDELSLKRQKSNHSMKEKDDNENINYITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFETHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEGVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEDLDLARVLDRLVLYLRIVHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYRRQSDPRHNGNYSNNNYNNNREANSYRKPGRSDFGNRNSNAGALYYSRKILNYNDISVAD 709
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BLAST of Serrate RNA effector molecule vs. Planmine SMEST
Match: SMESG000030605.1 (SMESG000030605.1)

HSP 1 Score: 589.726 bits (1519), Expect = 0.000e+0
Identity = 326/721 (45.21%), Postives = 474/721 (65.74%), Query Frame = 2 
Query:  194 RQKSNHSMKEKDDNENINYITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFACEQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENKYMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKKVYRADSPERTEIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDREAVVDVPKKELSPEIKSPEEMMANDELPAEGVDPRPLHKSCSVFIKNIHPKVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVWELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAKFDKRRHLWESDNDA---------NPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGRGGSTNDPNNIRMDEXXXXXXXXXXXXXXXXXXHSYDYYSATEYEIEDFLPNRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVASRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNKYADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPN----PSRAIK----LDHANAYRRQSDPRHXXXXXXXXXXXXREANSYRKP-------------GRSDFGNRNS-----------------------------NAGALYYSRKILNYNDI 2179
            R  SN S+ + DD  N  Y TQPPMLLFKHFL QQ+D+I ++ AM+KYNEYK++F  +QL++FF++H ++EWF EKY P ++E ++ +  +NI  RK++F +L+E  +MD + +H++  DS+ +L+D+ VILLEGG  +DL +L+ K YR++SP  + I  D+  K+ P  +      TSS     ++EI +               + +++   K+   EI+S E +    E  +E  +PR LHK+ S+F++N+HP V RS++E LVKP+ G++R+ALQDP P+RKF RRGWVT++R+ ++K + W LN  +L D D+GA+VN+E++QRIRP   + NH+ VMR D+K A++LVAKFDKR +LW+ ++           NPLL NITE+LVDEGSYEEEA LGG+++SNL +T  G    DP+NI+++ D  LA VLDRL+LYLR VHS+DYYS TEY+IED +P+RCG+LHARG  ++ D+ L+Q  +E+Y+K FE+KAEL+L+S++ L    A +LG K ++E+V+ FI +NT+EI+ +KWLCPLSGKKFKGPD+V+KHILNK+ D+++ VKQ  +FFNNY+LDP+RPQLPEHPSNRP      S  I+     D+ N     +D R+    +N N++   +    R+P             G  D GNRN+                             N G  YY+RK+L+YND+
Sbjct:  101 RFNSNSSIPKSDDTPN--YPTQPPMLLFKHFLQQQDDDIEMDQAMKKYNEYKDSFVTKQLKAFFDSHSNQEWFREKYSPQFVEKRKVELEKNIQLRKEIFTYLHERNWMDNIKIHVDENDSIVRLMDAVVILLEGGNAHDLTILDSKRYRSESPNDSHILEDVVVKS-PEKV------TSS----EEIEIVN---------------KEIIEPDDKKFEEEIESTENVEEKFEKKSELQEPRALHKTFSIFLRNLHPNVLRSEIEALVKPYSGFLRLALQDPTPDRKFFRRGWVTYDRTVNIKEICWNLNNIRLHDCDIGAIVNRELTQRIRPVMVLANHKPVMRHDIKIASRLVAKFDKRHNLWQREDGKDTTNPMSSNNPLLANITEYLVDEGSYEEEALLGGNLNSNLELTVTGS---DPSNIKVEVDDKLAAVLDRLILYLRFVHSFDYYSTTEYQIEDEMPHRCGILHARGAHIHVDKPLTQKEVEEYIKSFEMKAELILNSVELLTIDEAKKLGYKTLDESVDVFIAENTQEISKDKWLCPLSGKKFKGPDFVQKHILNKHMDKVELVKQNTEFFNNYLLDPKRPQLPEHPSNRPGVKTTESGEIRNEGQFDNNNKRFGDNDSRNRNMDNNRNFSRRNDDFDNRRPNYRNDRGSSPNGGGYRDSGNRNNNFGDNRGGSNGNYYRKSSYPSRGSQSRQRNGGGSYYARKVLSYNDL 790
The following BLAST results are available for this feature:
BLAST of Serrate RNA effector molecule vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SRRT2.597e-9144.72serrate, RNA effector molecule [Source:HGNC Symbol... [more]
SRRT4.706e-2543.20serrate, RNA effector molecule [Source:HGNC Symbol... [more]
SRRT4.713e-2543.20serrate, RNA effector molecule [Source:HGNC Symbol... [more]
SRRT4.731e-2543.20serrate, RNA effector molecule [Source:HGNC Symbol... [more]
SRRT4.738e-2543.20serrate, RNA effector molecule [Source:HGNC Symbol... [more]
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BLAST of Serrate RNA effector molecule vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
E01A2.24.164e-9034.21Serrate RNA effector molecule homolog [Source:Uni... [more]
E01A2.29.232e-6332.60Serrate RNA effector molecule homolog [Source:Uni... [more]
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BLAST of Serrate RNA effector molecule vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ars21.262e-8341.94gene:FBgn0033062 transcript:FBtr0086020[more]
Ars21.262e-8341.94gene:FBgn0033062 transcript:FBtr0086021[more]
Ars21.262e-8341.94gene:FBgn0033062 transcript:FBtr0086018[more]
Ars21.909e-8341.94gene:FBgn0033062 transcript:FBtr0310667[more]
Ars21.968e-8341.94gene:FBgn0033062 transcript:FBtr0310665[more]
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BLAST of Serrate RNA effector molecule vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
srrt1.265e-8242.98serrate RNA effector molecule homolog (Arabidopsis... [more]
srrt2.201e-8242.98serrate RNA effector molecule homolog (Arabidopsis... [more]
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BLAST of Serrate RNA effector molecule vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SRRT1.206e-11036.05serrate, RNA effector molecule [Source:HGNC Symbol... [more]
SRRT1.051e-10836.90serrate, RNA effector molecule [Source:HGNC Symbol... [more]
SRRT3.206e-8042.22serrate, RNA effector molecule [Source:HGNC Symbol... [more]
SRRT5.850e-8042.22serrate, RNA effector molecule [Source:HGNC Symbol... [more]
SRRT1.013e-7942.22serrate, RNA effector molecule [Source:HGNC Symbol... [more]
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BLAST of Serrate RNA effector molecule vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Srrt1.045e-7542.28serrate RNA effector molecule homolog (Arabidopsis... [more]
Srrt7.910e-4548.13serrate RNA effector molecule homolog (Arabidopsis... [more]
Srrt4.059e-2643.41serrate RNA effector molecule homolog (Arabidopsis... [more]
Srrt3.002e-2544.00serrate RNA effector molecule homolog (Arabidopsis... [more]
Srrt3.083e-2544.00serrate RNA effector molecule homolog (Arabidopsis... [more]
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BLAST of Serrate RNA effector molecule vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A8XEG9|SRRT_CAEBR1.735e-9135.04Serrate RNA effector molecule homolog OS=Caenorhab... [more]
sp|Q966L5|SRRT_CAEEL5.297e-8934.21Serrate RNA effector molecule homolog OS=Caenorhab... [more]
sp|Q17FR9|SRRT_AEDAE3.520e-8742.62Serrate RNA effector molecule homolog OS=Aedes aeg... [more]
sp|B4NYV0|SRRT_DROYA4.115e-8541.94Serrate RNA effector molecule homolog OS=Drosophil... [more]
sp|B4II37|SRRT_DROSE8.792e-8342.46Serrate RNA effector molecule homolog OS=Drosophil... [more]
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BLAST of Serrate RNA effector molecule vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0F7GYG77.959e-14147.27Serrate RNA effector molecule (Fragment) OS=Schmid... [more]
A0A4Y7NK302.561e-13339.87EOG090X04A7 OS=Moina brachiata OX=675436 GN=EOG090... [more]
A0A4Y7M6141.282e-13139.81EOG090X04A7 OS=Daphnia dolichocephala OX=2282166 G... [more]
A0A4Y7NJZ61.417e-13038.96EOG090X04A7 OS=Scapholeberis mucronata OX=202097 G... [more]
A0A4Y7M0Q03.987e-13040.44EOG090X04A7 OS=Daphnia barbata OX=414587 GN=EOG090... [more]
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BLAST of Serrate RNA effector molecule vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
srrt1.347e-1130.14serrate RNA effector molecule homolog (Arabidopsis... [more]
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BLAST of Serrate RNA effector molecule vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000010621.13.634e-10937.44pep scaffold:Pmarinus_7.0:GL476849:23359:42927:-1 ... [more]
ENSPMAT00000001670.12.029e-4629.86pep scaffold:Pmarinus_7.0:GL480784:6169:22985:1 ge... [more]
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BLAST of Serrate RNA effector molecule vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Serrate RNA effector molecule vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO462641.977e-3545.95Ars2/serrate-like protein; Predicted protein [Sou... [more]
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BLAST of Serrate RNA effector molecule vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
srrt9.271e-2443.90serrate, RNA effector molecule [Source:NCBI gene;A... [more]
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BLAST of Serrate RNA effector molecule vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000023055.10.000e+099.86SMESG000023055.1[more]
SMESG000030605.10.000e+045.21SMESG000030605.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027641 ID=SMED30027641|Name=Serrate RNA effector molecule|organism=Schmidtea mediterranea sexual|type=transcript|length=2330bp
ATCTATATAAATCTTATATGAGCACTCTACTAGAGAATTATTTATTTTAA
TCTAAGTAATTTAAATGAGCGATTCTGCATCAGACTACGGTGGTTGGGGT
AAAAACGAAGATAATAGAGGAATATCAAATCCTAAAACTGTGACGAAAAG
AAGTCATCCAAATGATTCCTTATCGGATGAGCTATCCTTAAAGCGTCAAA
AATCTAACCATTCAATGAAAGAAAAAGACGATAACGAAAATATAAATTAT
ATCACTCAACCACCTATGTTATTGTTTAAACATTTTCTTAATCAACAAGA
AGATAATATTCTAGTGGAGGATGCAATGCGAAAATATAACGAATATAAAG
AAGCTTTTGCATGTGAACAGCTTCAATCGTTTTTTGAAGCTCATAAAGAC
GAAGAATGGTTTATGGAGAAATATCATCCGGATTATATTGAAGCAAAAGA
ATTTAAAAGATTGGAAAATATTGACTCGCGCAAAAAAGTTTTCATGTGGT
TGTATGAGAATAAATATATGGATGAAGTTTCAGTCCATATTAATTATCAA
GATTCCTTATTTAAATTACTGGATTCAGCTGTTATTTTATTGGAAGGTGG
AACCGAGAATGATCTTCGAGTATTAGAGAAAAAAGTTTACAGAGCAGATT
CACCTGAAAGGACAGAAATTAAAATCGATATAAAATCGAAAAATGATCCA
AGTAGTTTGAAATGGGACGATTTTAATACTTCTAGTGGTGATGACGACAG
CGATGTTGAAATCACTTCTGGAGTGAAGGCTTCTGACCGGGATTCAGGTA
GAGAGAGTGATAGAGAGGCGGTTGTGGATGTGCCGAAAAAGGAGCTCTCT
CCTGAAATCAAAAGTCCCGAAGAAATGATGGCGAATGACGAATTGCCCGC
GGAAGGAGTCGATCCGAGACCTCTCCATAAGTCTTGCTCGGTTTTCATAA
AGAATATTCACCCGAAAGTATTTCGTTCTCAATTGGAAGAGCTAGTGAAA
CCGTTTCCAGGTTACGTGAGGATTGCGCTCCAGGATCCAATGCCAGAACG
GAAATTCCTGCGTCGGGGTTGGGTGACTTTTGAACGGAGCAGTGACGTGA
AAAATGTCGTTTGGGAGCTAAACAAAGCCAAACTGCTCGATGTGGATCTC
GGCGCTGTTGTCAACAAAGAAATCTCCCAACGAATCAGACCAACTCAGCC
CGTTACAAACCATCGGGCGGTGATGCGACAAGACGTGAAATACGCGGCAA
AACTGGTGGCGAAATTCGACAAACGGCGGCACCTATGGGAATCCGACAAT
GACGCAAATCCGTTGCTATGCAACATCACAGAGCATCTGGTCGATGAAGG
CAGCTACGAAGAGGAGGCGTATCTCGGTGGCGATATCAGCAGCAATTTGG
CAATCACCGGTAGGGGTGGCAGCACCAACGATCCCAACAATATCAGAATG
GACGAGGATCTCGATCTGGCCCGCGTGCTCGACCGACTCGTCCTCTACCT
GCGCATTGTCCATTCTTATGACTACTACTCGGCCACCGAGTACGAGATTG
AGGACTTCCTGCCGAACCGATGTGGCCTCTTGCATGCCCGTGGCAATCTC
CTGTATCCGGATCAGCGCCTCAGCCAGGCCCATTTAGAAAAGTACATGAA
GGATTTCGAGATCAAAGCGGAACTGGTACTGGATTCGATCGATAATCTCG
ATTTCGTTGTGGCTTCAAGGCTCGGCGTGAAAGGCATTGAGGAGGCAGTC
GAGAAATTTATCACAGACAACACGAAGGAAATCACCACAGAGAAATGGCT
GTGCCCATTGTCGGGTAAAAAGTTCAAAGGCCCGGATTACGTGCGGAAAC
ACATTCTCAATAAGTATGCCGATCGGATCGATAATGTCAAGCAGACCGTT
CAGTTCTTCAACAATTATATTCTCGATCCGAGGCGGCCACAACTACCGGA
ACACCCGTCGAATCGACCGAATCCGAGTCGGGCCATCAAGCTTGACCATG
CCAATGCTTACCGTAGACAATCGGATCCCCGCCATAACGGTAACTACAGC
AACAATAACTACAACAACAACCGTGAGGCGAACAGTTATAGGAAACCCGG
GAGATCTGATTTCGGTAACAGGAACTCCAATGCCGGCGCATTGTACTATT
CCAGGAAGATTCTGAATTATAATGATATTAGCGTTGCAGATTAATGTTTT
AATTATTGTTATATCATAAATTGTTTAGTAACTGTTTTTCTTTTGTAACC
TCCGGGACAACTTCCCCACCATTTGTGTGTGTAAACACTTTTATTATCCA
TTTCTTTCAATCATGAAGCTTACAGCAGAC
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protein sequence of SMED30027641-orf-1

>SMED30027641-orf-1 ID=SMED30027641-orf-1|Name=SMED30027641-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=710bp
MSDSASDYGGWGKNEDNRGISNPKTVTKRSHPNDSLSDELSLKRQKSNHS
MKEKDDNENINYITQPPMLLFKHFLNQQEDNILVEDAMRKYNEYKEAFAC
EQLQSFFEAHKDEEWFMEKYHPDYIEAKEFKRLENIDSRKKVFMWLYENK
YMDEVSVHINYQDSLFKLLDSAVILLEGGTENDLRVLEKKVYRADSPERT
EIKIDIKSKNDPSSLKWDDFNTSSGDDDSDVEITSGVKASDRDSGRESDR
EAVVDVPKKELSPEIKSPEEMMANDELPAEGVDPRPLHKSCSVFIKNIHP
KVFRSQLEELVKPFPGYVRIALQDPMPERKFLRRGWVTFERSSDVKNVVW
ELNKAKLLDVDLGAVVNKEISQRIRPTQPVTNHRAVMRQDVKYAAKLVAK
FDKRRHLWESDNDANPLLCNITEHLVDEGSYEEEAYLGGDISSNLAITGR
GGSTNDPNNIRMDEDLDLARVLDRLVLYLRIVHSYDYYSATEYEIEDFLP
NRCGLLHARGNLLYPDQRLSQAHLEKYMKDFEIKAELVLDSIDNLDFVVA
SRLGVKGIEEAVEKFITDNTKEITTEKWLCPLSGKKFKGPDYVRKHILNK
YADRIDNVKQTVQFFNNYILDPRRPQLPEHPSNRPNPSRAIKLDHANAYR
RQSDPRHNGNYSNNNYNNNREANSYRKPGRSDFGNRNSNAGALYYSRKIL
NYNDISVAD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006397mRNA processing
GO:0006351transcription, DNA-templated
GO:0006355regulation of transcription, DNA-templated
GO:0008283cell proliferation
GO:0031047gene silencing by RNA
GO:0031053primary miRNA processing
GO:0097150neuronal stem cell population maintenance
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR039727SE/Ars2
IPR035979RBD_domain_sf
IPR021933SERRATE/Ars2_N
IPR007042SERRATE/Ars2_C
IPR012677Nucleotide-bd_a/b_plait_sf
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0003676nucleic acid binding
GO:0003677DNA binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005654nucleoplasm
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 214..373
e-value: 1.0E-6
score: 30.7
IPR007042SERRATE/Ars2 , C-terminalPFAMPF04959ARS2coord: 515..684
e-value: 9.3E-41
score: 140.4
IPR021933SERRATE/Ars2, N-terminalPFAMPF12066DUF3546coord: 72..181
e-value: 2.4E-29
score: 101.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..59
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 220..269
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 31..59
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 231..269
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 653..684
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 651..684
NoneNo IPR availablePANTHERPTHR13165:SF0SERRATE RNA EFFECTOR MOLECULE HOMOLOGcoord: 9..659
NoneNo IPR availableCDDcd00590RRM_SFcoord: 293..357
e-value: 2.42069E-6
score: 43.4477
IPR039727SERRATE/Ars2PANTHERPTHR13165ARSENITE-RESISTANCE PROTEIN 2coord: 9..659
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 280..357