Nucleolysin TIAR

Overview
NameNucleolysin TIAR
Smed IDSMED30027620
Length (bp)816
Neoblast Clusters

Zeng et. al., 2018




 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30027620

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
muscle cellSMED30027620h1SMcG0006642 dd_Smed_v4_19588_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30027620h1SMcG0006642 dd_Smed_v6_19588_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Nucleolysin TIAR vs. Ensembl Human
Match: TIA1 (TIA1 cytotoxic granule associated RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11802])

HSP 1 Score: 108.997 bits (271), Expect = 8.135e-27
Identity = 80/258 (31.01%), Postives = 128/258 (49.61%), Query Frame = 1
Query:   28 GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAE--STPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            G C++C +++   G + +    ++ + H      ALA++    ++ ++V V +  TP ++   T    + S    ++   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L+YD V N+S  +N TV+  G+   LT QL    F  FG+I  I  FP++ Y+F+ F +H+ A  AI   +G  I G  +KCYWGK
Sbjct:   31 GPCKNCKMIMDTAGNDPYCFVEFHEHRHAA---AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGK 285          

HSP 2 Score: 58.151 bits (139), Expect = 3.669e-9
Identity = 51/199 (25.63%), Postives = 84/199 (42.21%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            + D     ++VGN+   + E ++ + FSQ GP  N K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    +  +V  +  + +  VFV  +  E+T +     F  FGRI       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K     S   +N K
Sbjct:    1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198          
BLAST of Nucleolysin TIAR vs. Ensembl Human
Match: TIA1 (TIA1 cytotoxic granule associated RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11802])

HSP 1 Score: 108.612 bits (270), Expect = 8.845e-27
Identity = 80/258 (31.01%), Postives = 128/258 (49.61%), Query Frame = 1
Query:   28 GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAE--STPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            G C++C +++   G + +    ++ + H      ALA++    ++ ++V V +  TP ++   T    + S    ++   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L+YD V N+S  +N TV+  G+   LT QL    F  FG+I  I  FP++ Y+F+ F +H+ A  AI   +G  I G  +KCYWGK
Sbjct:   31 GPCKNCKMIMDTAGNDPYCFVEFHEHRHAA---AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGK 285          

HSP 2 Score: 58.151 bits (139), Expect = 4.031e-9
Identity = 51/199 (25.63%), Postives = 84/199 (42.21%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            + D     ++VGN+   + E ++ + FSQ GP  N K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    +  +V  +  + +  VFV  +  E+T +     F  FGRI       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K     S   +N K
Sbjct:    1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198          
BLAST of Nucleolysin TIAR vs. Ensembl Human
Match: TIA1 (TIA1 cytotoxic granule associated RNA binding protein [Source:HGNC Symbol;Acc:HGNC:11802])

HSP 1 Score: 106.301 bits (264), Expect = 5.224e-26
Identity = 79/256 (30.86%), Postives = 125/256 (48.83%), Query Frame = 1
Query:   28 GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            G C++C +++   G + +    ++ + H      ALA++    ++ ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L+YD V N+S  +N TV+  G+   LT QL    F  FG+I  I  FP++ Y+F+ F +H+ A  AI   +G  I G  +KCYWGK
Sbjct:   31 GPCKNCKMIMDTAGNDPYCFVEFHEHRHAA---AALAAMNGRKIMGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGK 274          

HSP 2 Score: 52.7582 bits (125), Expect = 2.315e-7
Identity = 50/197 (25.38%), Postives = 79/197 (40.10%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            + D     ++VGN+   + E ++ + FSQ GP  N K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    N+  V+   L           E+T +     F  FGRI       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K     S   +N K
Sbjct:    1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSP---------EITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 187          
BLAST of Nucleolysin TIAR vs. Ensembl Human
Match: TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:HGNC Symbol;Acc:HGNC:11804])

HSP 1 Score: 105.145 bits (261), Expect = 1.657e-25
Identity = 73/213 (34.27%), Postives = 105/213 (49.30%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP------LNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK         L ++ V N+S   N TV+  GI   LT QL    F  FG+I  I  FPE+ Y+F+ F+TH+ A  AI   +G  I G  +KCYWGK
Sbjct:   73 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGK 276          

HSP 2 Score: 50.8322 bits (120), Expect = 1.025e-6
Identity = 48/196 (24.49%), Postives = 79/196 (40.31%), Query Frame = 1
Query:  241 NDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDN------INNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            +D     ++VGN+   + E ++ + FSQ GP  + K+I   +  +  + FV F     A  A+  MN  ++    +K N+A   +  K    N+  V+   L           E+T +     F  FG+I +      +     + Y F+SF    +A  AI    G  + G  I+  W   K     S   NN K
Sbjct:    4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITE-HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSP---------EITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTK 189          
BLAST of Nucleolysin TIAR vs. Ensembl Human
Match: TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:HGNC Symbol;Acc:HGNC:11804])

HSP 1 Score: 105.145 bits (261), Expect = 1.763e-25
Identity = 73/213 (34.27%), Postives = 105/213 (49.30%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP------LNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK         L ++ V N+S   N TV+  GI   LT QL    F  FG+I  I  FPE+ Y+F+ F+TH+ A  AI   +G  I G  +KCYWGK
Sbjct:   90 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGK 293          
BLAST of Nucleolysin TIAR vs. Ensembl Celegans
Match: tiar-1 (TIA-1/TIAL RNA binding protein homolog [Source:UniProtKB/TrEMBL;Acc:Q95QV8])

HSP 1 Score: 120.168 bits (300), Expect = 2.748e-31
Identity = 80/244 (32.79%), Postives = 119/244 (48.77%), Query Frame = 1
Query:   55 IIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIP-----LNYDLVYNESLETNTTVFVSGI-ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +IFDG N  Y   +  +  +    QAL ++    +LDR++ V +   P  +        S I+      VFVG++   ++   L+EAF  FG V + KVIR  N   SKG+ FVS+     A +AI+ MN   L    I+ N+A    G +  P      +YD +YN++   NT+V+V  I  LT       F +FGRI  +  F  + YAF+ F     A KAI Q +   + G  ++C WGK
Sbjct:   77 VIFDGSNDPY--AFVEFSDHGQASQALQTMNKRLLLDREMKVNWAVEPGQQQ-------SKIDTTRHFHVFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQMNGQWLGRRTIRTNWATRKPGDQEKPSHYNEKSYDEIYNQTSGDNTSVYVGNIASLTEDEIRQGFASFGRITEVRIFKMQGYAFVKFDNKDAAAKAIVQMNNQDVGGQLVRCSWGK 311          

HSP 2 Score: 56.9954 bits (136), Expect = 4.012e-9
Identity = 49/191 (25.65%), Postives = 87/191 (45.55%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            ++VGN+   + E  +   F+Q G V   KVI   +  +  +AFV FS+   A++A+  MN+  L +  +K N+A+   G +   ++    ++        VFV  +  E+  Q     F+ FG +       + N    + Y F+S+   +EA +AI Q +G  +    I+  W   K   Q   ++ N K
Sbjct:   48 LYVGNLDSTVTEDFIATLFNQIGSVTKTKVIF--DGSNDPYAFVEFSDHGQASQALQTMNKRLLLDREMKVNWAV-EPGQQQSKIDTTRHFH--------VFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQMNGQWLGRRTIRTNWATRKPGDQEKPSHYNEK 227          
BLAST of Nucleolysin TIAR vs. Ensembl Celegans
Match: tiar-1 (TIA-1/TIAL RNA binding protein homolog [Source:UniProtKB/TrEMBL;Acc:Q95QV8])

HSP 1 Score: 113.62 bits (283), Expect = 4.961e-29
Identity = 72/218 (33.03%), Postives = 108/218 (49.54%), Query Frame = 1
Query:  133 LASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIP-----LNYDLVYNESLETNTTVFVSGI-ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +A+++N      +  VIFD   +  +    +  S I+      VFVG++   ++   L+EAF  FG V + KVIR  N   SKG+ FVS+     A +AI+ MN   L    I+ N+A    G +  P      +YD +YN++   NT+V+V  I  LT       F +FGRI  +  F  + YAF+ F     A KAI Q +   + G  ++C WGK
Sbjct:   62 IATLFNQIGSVTKTKVIFDEMKVNWAVEPGQQQSKIDTTRHFHVFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQMNGQWLGRRTIRTNWATRKPGDQEKPSHYNEKSYDEIYNQTSGDNTSVYVGNIASLTEDEIRQGFASFGRITEVRIFKMQGYAFVKFDNKDAAAKAIVQMNNQDVGGQLVRCSWGK 279          
BLAST of Nucleolysin TIAR vs. Ensembl Celegans
Match: tiar-1 (TIA-1/TIAL RNA binding protein homolog [Source:UniProtKB/TrEMBL;Acc:Q95QV8])

HSP 1 Score: 111.694 bits (278), Expect = 6.687e-29
Identity = 71/210 (33.81%), Postives = 104/210 (49.52%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIP-----LNYDLVYNESLETNTTVFVSGI-ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +LDR++ V +   P  +        S I+      VFVG++   ++   L+EAF  FG V + KVIR  N   SKG+ FVS+     A +AI+ MN   L    I+ N+A    G +  P      +YD +YN++   NT+V+V  I  LT       F +FGRI  +  F  + YAF+ F     A KAI Q +   + G  ++C WGK
Sbjct:    6 LLDREMKVNWAVEPGQQQ-------SKIDTTRHFHVFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQMNGQWLGRRTIRTNWATRKPGDQEKPSHYNEKSYDEIYNQTSGDNTSVYVGNIASLTEDEIRQGFASFGRITEVRIFKMQGYAFVKFDNKDAAAKAIVQMNNQDVGGQLVRCSWGK 208          
BLAST of Nucleolysin TIAR vs. Ensembl Celegans
Match: tiar-1 (TIA-1/TIAL RNA binding protein homolog [Source:UniProtKB/TrEMBL;Acc:Q95QV8])

HSP 1 Score: 109.383 bits (272), Expect = 4.904e-28
Identity = 64/175 (36.57%), Postives = 91/175 (52.00%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIP-----LNYDLVYNESLETNTTVFVSGI-ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            VFVG++   ++   L+EAF  FG V + KVIR  N   SKG+ FVS+     A +AI+ MN   L    I+ N+A    G +  P      +YD +YN++   NT+V+V  I  LT       F +FGRI  +  F  + YAF+ F     A KAI Q +   + G  ++C WGK
Sbjct:   24 VFVGDLSSEVDNQKLREAFQPFGDVSDAKVIRDTNTTKSKGYGFVSYPKREEAERAIEQMNGQWLGRRTIRTNWATRKPGDQEKPSHYNEKSYDEIYNQTSGDNTSVYVGNIASLTEDEIRQGFASFGRITEVRIFKMQGYAFVKFDNKDAAAKAIVQMNNQDVGGQLVRCSWGK 198          
BLAST of Nucleolysin TIAR vs. Ensembl Celegans
Match: tiar-2 (TIA-1/TIAL RNA binding protein homolog [Source:UniProtKB/TrEMBL;Acc:Q9U2F5])

HSP 1 Score: 94.3597 bits (233), Expect = 8.311e-22
Identity = 75/262 (28.63%), Postives = 112/262 (42.75%), Query Frame = 1
Query:   55 IIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPN-KISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPK-----------------------HIPLNYDLVYNESLETNTTVFVSGIE-LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            IIF+G+N  Y   +  +  +     AL S     +L++++ V +   P  E    R  P          VFVG++   I+   L+EAF +FG V   K+IR  N    KG+ FVS+     A +AID MN   L    I+ N+A                                   YD ++N++   NT+V+V  I  L        F  FG I+ +  F  + YAF+ F T + A +AI Q +   I G  ++C WGK
Sbjct:   71 IIFEGLNDPY--AFVEFSDHNQATLALQSHNGRELLEKEMHVTWAFEP-REPGENRSKPETSRH---FHVFVGDLCSEIDSTKLREAFVKFGEVSEAKIIRDNNTNKGKGYGFVSYPRREDAERAIDEMNGAWLGRRTIRTNWATRKPDEDGERGGDRGDRRGGGGGGRDRYHNQSEKTYDEIFNQAAADNTSVYVGNIANLGEDEIRRAFDRFGPINEVRTFKIQGYAFVKFETKESAARAIVQMNNADIGGQIVRCSWGK 326          
BLAST of Nucleolysin TIAR vs. Ensembl Fly
Match: trv (gene:FBgn0085391 transcript:FBtr0334897)

HSP 1 Score: 111.309 bits (277), Expect = 1.236e-27
Identity = 69/191 (36.13%), Postives = 103/191 (53.93%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGPKHI-PLNYDLVYNESLETNTTVFVSGI-----ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNR 807
            +FVG++   I    L+EAF+ FG + + +V+R P  + SKG+ FVSF   S A  AI  MN   L +  I+ N+A        ++I PL +D VYN+S  +N TV+V G+      L+ ++    F  +G I  I  F ++ YAF+ F+T + AT AI   H   IN   +KC WGK     ++ D NN +
Sbjct:  168 IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGK-----ESGDPNNAQ 353          
BLAST of Nucleolysin TIAR vs. Ensembl Fly
Match: trv (gene:FBgn0085391 transcript:FBtr0344218)

HSP 1 Score: 111.694 bits (278), Expect = 1.255e-27
Identity = 69/191 (36.13%), Postives = 103/191 (53.93%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGPKHI-PLNYDLVYNESLETNTTVFVSGI-----ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNR 807
            +FVG++   I    L+EAF+ FG + + +V+R P  + SKG+ FVSF   S A  AI  MN   L +  I+ N+A        ++I PL +D VYN+S  +N TV+V G+      L+ ++    F  +G I  I  F ++ YAF+ F+T + AT AI   H   IN   +KC WGK     ++ D NN +
Sbjct:  168 IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGK-----ESGDPNNAQ 353          
BLAST of Nucleolysin TIAR vs. Ensembl Fly
Match: trv (gene:FBgn0085391 transcript:FBtr0112583)

HSP 1 Score: 111.309 bits (277), Expect = 1.293e-27
Identity = 69/191 (36.13%), Postives = 103/191 (53.93%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGPKHI-PLNYDLVYNESLETNTTVFVSGI-----ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNR 807
            +FVG++   I    L+EAF+ FG + + +V+R P  + SKG+ FVSF   S A  AI  MN   L +  I+ N+A        ++I PL +D VYN+S  +N TV+V G+      L+ ++    F  +G I  I  F ++ YAF+ F+T + AT AI   H   IN   +KC WGK     ++ D NN +
Sbjct:  168 IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGK-----ESGDPNNAQ 353          
BLAST of Nucleolysin TIAR vs. Ensembl Fly
Match: trv (gene:FBgn0085391 transcript:FBtr0334896)

HSP 1 Score: 111.309 bits (277), Expect = 1.679e-27
Identity = 69/191 (36.13%), Postives = 103/191 (53.93%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGPKHI-PLNYDLVYNESLETNTTVFVSGI-----ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNR 807
            +FVG++   I    L+EAF+ FG + + +V+R P  + SKG+ FVSF   S A  AI  MN   L +  I+ N+A        ++I PL +D VYN+S  +N TV+V G+      L+ ++    F  +G I  I  F ++ YAF+ F+T + AT AI   H   IN   +KC WGK     ++ D NN +
Sbjct:  168 IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGK-----ESGDPNNAQ 353          
BLAST of Nucleolysin TIAR vs. Ensembl Fly
Match: trv (gene:FBgn0085391 transcript:FBtr0344217)

HSP 1 Score: 111.309 bits (277), Expect = 2.581e-27
Identity = 69/191 (36.13%), Postives = 103/191 (53.93%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGPKHI-PLNYDLVYNESLETNTTVFVSGI-----ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNR 807
            +FVG++   I    L+EAF+ FG + + +V+R P  + SKG+ FVSF   S A  AI  MN   L +  I+ N+A        ++I PL +D VYN+S  +N TV+V G+      L+ ++    F  +G I  I  F ++ YAF+ F+T + AT AI   H   IN   +KC WGK     ++ D NN +
Sbjct:  314 IFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGK-----ESGDPNNAQ 499          
BLAST of Nucleolysin TIAR vs. Ensembl Zebrafish
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:ZFIN;Acc:ZDB-GENE-030131-1506])

HSP 1 Score: 107.842 bits (268), Expect = 1.278e-26
Identity = 78/264 (29.55%), Postives = 129/264 (48.86%), Query Frame = 1
Query:   10 LNGQIFGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGI---------TGPKHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            L GQI G C+ C +++   G + +    ++ + H      +LA++    ++ ++V V +  +P ++           +  N   VFVG++   I    ++ AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A            T  KH  L++D V N+S  +N TV+  G+   LT QL    F  FG+I  +  FP++ Y+F+ F +H+ A  AI   +G  + G  +KCYWGK
Sbjct:   27 LFGQI-GPCKSCKMIVDTAGNDPYCFVEFFEHRH---AAASLAAMNGRKIMGKEVKVNWATSPSSQKK---------DTSNHFHVFVGDLSPEITTDDIRAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKATYETNTKH--LSFDEVVNQSSPSNCTVYCGGVTTGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFNSHESAAHAIVSVNGTSLEGHIVKCYWGK 275          

HSP 2 Score: 51.9878 bits (123), Expect = 2.953e-7
Identity = 44/184 (23.91%), Postives = 74/184 (40.22%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGK 771
            ++D     ++VGN+   + E ++ + F Q GP  + K+I      +  + FV F     A  ++  MN  ++    +K N+A   +  K    N+  V+   L           E+T       F  FGRI       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K
Sbjct:    2 MDDEQPKTLYVGNLSRDVTEALIMQLFGQIGPCKSCKMIVD-TAGNDPYCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWATSPSSQKKDTSNHFHVFVGDLSP---------EITTDDIRAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 175          
BLAST of Nucleolysin TIAR vs. Ensembl Zebrafish
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:ZFIN;Acc:ZDB-GENE-030131-1506])

HSP 1 Score: 107.842 bits (268), Expect = 1.372e-26
Identity = 78/264 (29.55%), Postives = 129/264 (48.86%), Query Frame = 1
Query:   10 LNGQIFGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGI---------TGPKHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            L GQI G C+ C +++   G + +    ++ + H      +LA++    ++ ++V V +  +P ++           +  N   VFVG++   I    ++ AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A            T  KH  L++D V N+S  +N TV+  G+   LT QL    F  FG+I  +  FP++ Y+F+ F +H+ A  AI   +G  + G  +KCYWGK
Sbjct:   27 LFGQI-GPCKSCKMIVDTAGNDPYCFVEFFEHRH---AAASLAAMNGRKIMGKEVKVNWATSPSSQKK---------DTSNHFHVFVGDLSPEITTDDIRAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKATYETNTKH--LSFDEVVNQSSPSNCTVYCGGVTTGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFNSHESAAHAIVSVNGTSLEGHIVKCYWGK 275          

HSP 2 Score: 49.2914 bits (116), Expect = 2.374e-6
Identity = 43/175 (24.57%), Postives = 70/175 (40.00%), Query Frame = 1
Query:  265 FVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDN------INNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGK 771
            +VGN+   + E ++ + F Q GP  + K+I      +  + FV F     A  ++  MN  ++    +K N+A   +  K    N+  V+   L           E+T       F  FGRI +      +     + Y F+SF    +A  AI Q  G  + G  I+  W   K
Sbjct:   11 YVGNLSRDVTEALIMQLFGQIGPCKSCKMIVD-TAGNDPYCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWATSPSSQKKDTSNHFHVFVGDLSP---------EITTDDIRAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 175          
BLAST of Nucleolysin TIAR vs. Ensembl Zebrafish
Match: tia1l (cytotoxic granule-associated RNA binding protein 1, like [Source:ZFIN;Acc:ZDB-GENE-030131-2167])

HSP 1 Score: 106.686 bits (265), Expect = 1.674e-26
Identity = 81/263 (30.80%), Postives = 126/263 (47.91%), Query Frame = 1
Query:   19 QIF---GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGI--------TGPKHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            Q+F   G C+ C +++   G + +    +Y   H      ALA++    +L + + V +  TP ++           +  N   VFVG++   I+   ++ AF+ FG + + +V+R      SKG+ F+SF N   A  AI  MN   L    I+ N+A            G     L+Y+ V N+S  +N TV+  GI   L+ QL    F  FG+I  I  FPE+ Y+F+ F +H+ A  AI   +G  I G  +KCYWGK
Sbjct:   27 QVFSQIGPCKSCKMILDTTGNDPYCFVEFYENRHAA---AALAAMNGRKILGKDMKVNWASTPSSQKK---------DTSNHFHVFVGDLSPEISTDDVRAAFAPFGKISDARVVRDLATGKSKGYGFISFINKWDAESAIQQMNGQWLGGRQIRTNWATRKPSAPKSNNEGASSKHLSYEEVLNQSSPSNCTVYCGGIASGLSDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFDSHEGAAHAIVSVNGTCIEGHTVKCYWGK 277          

HSP 2 Score: 46.9802 bits (110), Expect = 9.963e-6
Identity = 46/184 (25.00%), Postives = 76/184 (41.30%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDN------INNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDN 795
            ++VGN+   + E ++ + FSQ GP  + K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    N+  V+   L           E++       F  FG+I +      +     + Y FISF    +A  AI Q +G  + G  I+  W   K     S+N
Sbjct:   11 LYVGNLSRDVTEALILQVFSQIGPCKSCKMILDTTG-NDPYCFVEFYENRHAAAALAAMNGRKILGKDMKVNWASTPSSQKKDTSNHFHVFVGDLSP---------EISTDDVRAAFAPFGKISDARVVRDLATGKSKGYGFISFINKWDAESAIQQMNGQWLGGRQIRTNWATRKPSAPKSNN 184          
BLAST of Nucleolysin TIAR vs. Ensembl Zebrafish
Match: tia1l (cytotoxic granule-associated RNA binding protein 1, like [Source:ZFIN;Acc:ZDB-GENE-030131-2167])

HSP 1 Score: 105.145 bits (261), Expect = 5.425e-26
Identity = 80/263 (30.42%), Postives = 126/263 (47.91%), Query Frame = 1
Query:   19 QIF---GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGI--------TGPKHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            Q+F   G C+ C +++   G + +    +Y   H      ALA++    +L + + V +  TP ++           +  N   VFVG++   I+   ++ AF+ FG + + +V++      SKG+ F+SF N   A  AI  MN   L    I+ N+A            G     L+Y+ V N+S  +N TV+  GI   L+ QL    F  FG+I  I  FPE+ Y+F+ F +H+ A  AI   +G  I G  +KCYWGK
Sbjct:   27 QVFSQIGPCKSCKMILDTTGNDPYCFVEFYENRHAA---AALAAMNGRKILGKDMKVNWASTPSSQKK---------DTSNHFHVFVGDLSPEISTDDVRAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAESAIQQMNGQWLGGRQIRTNWATRKPSAPKSNNEGASSKHLSYEEVLNQSSPSNCTVYCGGIASGLSDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFDSHEGAAHAIVSVNGTCIEGHTVKCYWGK 277          
BLAST of Nucleolysin TIAR vs. Ensembl Zebrafish
Match: tial1 (TIA1 cytotoxic granule-associated RNA binding protein-like 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1547])

HSP 1 Score: 105.145 bits (261), Expect = 1.031e-25
Identity = 72/213 (33.80%), Postives = 106/213 (49.77%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP------LNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I    ++ AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK +       L +D V N+S   N TV+  GI+  LT  L    F  FG+I  I  FPE+ Y+FI F++H+ A  AI   +G  I G  +KCYWGK
Sbjct:   72 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGK 275          
BLAST of Nucleolysin TIAR vs. Ensembl Xenopus
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:NCBI gene;Acc:394890])

HSP 1 Score: 112.849 bits (281), Expect = 2.553e-28
Identity = 76/259 (29.34%), Postives = 127/259 (49.03%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPI--RKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
             G C+ C +++   G + +    ++ + H      +LA++    ++ ++V V +  TP ++        + S +  ++   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L Y+ V N+S  +N TV+  G+   LT QL    F  FG+I  +  FP++ Y+F+ F++H+ A  AI   +G  I G  +KCYWGK
Sbjct:   30 LGPCKSCKMIMDTAGNDPYCFVEFFEHRHAAA---SLAAMNGRKIMGKEVKVNWATTPSSQKKDANSSSVVSTLRSQDHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLTYEEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGK 285          

HSP 2 Score: 58.151 bits (139), Expect = 3.323e-9
Identity = 48/191 (25.13%), Postives = 80/191 (41.88%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRIDN------INNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            ++VGN+   + E ++ + FSQ GP  + K+I      +  + FV F     A  ++  MN  ++    +K N+A   +  K    +  +V     + +  VFV  +  E+T       F  FGRI +      +     + Y F+SF    +A  AI Q  G  + G  I+  W   K     S   +N K
Sbjct:    9 LYVGNLSRDVTEPLILQVFSQLGPCKSCKMIMD-TAGNDPYCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWATTPSSQKKDANSSSVVSTLRSQDHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198          
BLAST of Nucleolysin TIAR vs. Ensembl Xenopus
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:NCBI gene;Acc:394890])

HSP 1 Score: 112.464 bits (280), Expect = 3.449e-28
Identity = 76/259 (29.34%), Postives = 127/259 (49.03%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPI--RKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
             G C+ C +++   G + +    ++ + H      +LA++    ++ ++V V +  TP ++        + S +  ++   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L Y+ V N+S  +N TV+  G+   LT QL    F  FG+I  +  FP++ Y+F+ F++H+ A  AI   +G  I G  +KCYWGK
Sbjct:   39 LGPCKSCKMIMDTAGNDPYCFVEFFEHRHAAA---SLAAMNGRKIMGKEVKVNWATTPSSQKKDANSSSVVSTLRSQDHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLTYEEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGK 294          

HSP 2 Score: 57.7658 bits (138), Expect = 5.210e-9
Identity = 48/190 (25.26%), Postives = 79/190 (41.58%), Query Frame = 1
Query:  265 FVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRIDN------INNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            +VGN+   + E ++ + FSQ GP  + K+I      +  + FV F     A  ++  MN  ++    +K N+A   +  K    +  +V     + +  VFV  +  E+T       F  FGRI +      +     + Y F+SF    +A  AI Q  G  + G  I+  W   K     S   +N K
Sbjct:   19 YVGNLSRDVTEPLILQVFSQLGPCKSCKMIMD-TAGNDPYCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWATTPSSQKKDANSSSVVSTLRSQDHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 207          
BLAST of Nucleolysin TIAR vs. Ensembl Xenopus
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:NCBI gene;Acc:394890])

HSP 1 Score: 109.768 bits (273), Expect = 2.413e-27
Identity = 76/257 (29.57%), Postives = 124/257 (48.25%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
             G C+ C +++   G + +    ++ + H      +LA++    ++ ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L Y+ V N+S  +N TV+  G+   LT QL    F  FG+I  +  FP++ Y+F+ F++H+ A  AI   +G  I G  +KCYWGK
Sbjct:   14 LGPCKSCKMIMDTAGNDPYCFVEFFEHRHAAA---SLAAMNGRKIMGKEVKVNWATTPSSQKK---------DANNHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLTYEEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGK 258          
BLAST of Nucleolysin TIAR vs. Ensembl Xenopus
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:NCBI gene;Acc:394890])

HSP 1 Score: 109.383 bits (272), Expect = 2.581e-27
Identity = 76/257 (29.57%), Postives = 124/257 (48.25%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
             G C+ C +++   G + +    ++ + H      +LA++    ++ ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L Y+ V N+S  +N TV+  G+   LT QL    F  FG+I  +  FP++ Y+F+ F++H+ A  AI   +G  I G  +KCYWGK
Sbjct:    8 LGPCKSCKMIMDTAGNDPYCFVEFFEHRHAAA---SLAAMNGRKIMGKEVKVNWATTPSSQKK---------DANNHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLTYEEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGK 252          
BLAST of Nucleolysin TIAR vs. Ensembl Xenopus
Match: tia1 (TIA1 cytotoxic granule-associated RNA binding protein [Source:NCBI gene;Acc:394890])

HSP 1 Score: 109.768 bits (273), Expect = 3.194e-27
Identity = 76/257 (29.57%), Postives = 124/257 (48.25%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
             G C+ C +++   G + +    ++ + H      +LA++    ++ ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L Y+ V N+S  +N TV+  G+   LT QL    F  FG+I  +  FP++ Y+F+ F++H+ A  AI   +G  I G  +KCYWGK
Sbjct:   32 LGPCKSCKMIMDTAGNDPYCFVEFFEHRHAAA---SLAAMNGRKIMGKEVKVNWATTPSSQKK---------DANNHFHVFVGDLSPEITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLTYEEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGK 276          

HSP 2 Score: 57.3806 bits (137), Expect = 7.064e-9
Identity = 48/196 (24.49%), Postives = 79/196 (40.31%), Query Frame = 1
Query:  241 NDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            +D   + ++VGN+   + E ++ + FSQ GP  + K+I      +  + FV F     A  ++  MN  ++    +K N+A   +  K    N+  V+   L           E+T       F  FGRI       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K     S   +N K
Sbjct:    4 DDTKTILLYVGNLSRDVTEPLILQVFSQLGPCKSCKMIMD-TAGNDPYCFVEFFEHRHAAASLAAMNGRKIMGKEVKVNWATTPSSQKKDANNHFHVFVGDLSP---------EITTDDIKAAFAPFGRISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 189          
BLAST of Nucleolysin TIAR vs. Ensembl Mouse
Match: Tia1 (cytotoxic granule-associated RNA binding protein 1 [Source:MGI Symbol;Acc:MGI:107914])

HSP 1 Score: 107.457 bits (267), Expect = 1.493e-26
Identity = 79/258 (30.62%), Postives = 128/258 (49.61%), Query Frame = 1
Query:   28 GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAE--STPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            G C++C +++   G + +    ++ + H      ALA++    ++ ++V V +  TP ++   T    + S    ++   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L+YD V ++S   N TV+  G+   LT QL    F  FG+I  I  FP++ Y+F+ F++H+ A  AI   +G  I G  +KCYWGK
Sbjct:   31 GPCKNCKMIMDTAGNDPYCFVEFHEHRHAA---AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGK 285          

HSP 2 Score: 58.9214 bits (141), Expect = 1.710e-9
Identity = 51/199 (25.63%), Postives = 84/199 (42.21%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            + D     ++VGN+   + E ++ + FSQ GP  N K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    +  +V  +  + +  VFV  +  E+T +     F  FGRI       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K     S   +N K
Sbjct:    1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198          
BLAST of Nucleolysin TIAR vs. Ensembl Mouse
Match: Tia1 (cytotoxic granule-associated RNA binding protein 1 [Source:MGI Symbol;Acc:MGI:107914])

HSP 1 Score: 107.457 bits (267), Expect = 1.606e-26
Identity = 79/258 (30.62%), Postives = 128/258 (49.61%), Query Frame = 1
Query:   28 GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAE--STPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            G C++C +++   G + +    ++ + H      ALA++    ++ ++V V +  TP ++   T    + S    ++   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L+YD V ++S   N TV+  G+   LT QL    F  FG+I  I  FP++ Y+F+ F++H+ A  AI   +G  I G  +KCYWGK
Sbjct:   31 GPCKNCKMIMDTAGNDPYCFVEFHEHRHAA---AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGK 285          

HSP 2 Score: 58.9214 bits (141), Expect = 1.652e-9
Identity = 51/199 (25.63%), Postives = 84/199 (42.21%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            + D     ++VGN+   + E ++ + FSQ GP  N K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    +  +V  +  + +  VFV  +  E+T +     F  FGRI       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K     S   +N K
Sbjct:    1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198          
BLAST of Nucleolysin TIAR vs. Ensembl Mouse
Match: Tial1 (Tia1 cytotoxic granule-associated RNA binding protein-like 1 [Source:MGI Symbol;Acc:MGI:107913])

HSP 1 Score: 105.145 bits (261), Expect = 5.866e-26
Identity = 73/213 (34.27%), Postives = 105/213 (49.30%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP------LNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK         L ++ V N+S   N TV+  GI   LT QL    F  FG+I  I  FPE+ Y+F+ F+TH+ A  AI   +G  I G  +KCYWGK
Sbjct:   34 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGK 237          
BLAST of Nucleolysin TIAR vs. Ensembl Mouse
Match: Tial1 (Tia1 cytotoxic granule-associated RNA binding protein-like 1 [Source:MGI Symbol;Acc:MGI:107913])

HSP 1 Score: 105.145 bits (261), Expect = 1.173e-25
Identity = 73/213 (34.27%), Postives = 105/213 (49.30%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP------LNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK         L ++ V N+S   N TV+  GI   LT QL    F  FG+I  I  FPE+ Y+F+ F+TH+ A  AI   +G  I G  +KCYWGK
Sbjct:   73 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGK 276          

HSP 2 Score: 48.9062 bits (115), Expect = 2.881e-6
Identity = 47/196 (23.98%), Postives = 78/196 (39.80%), Query Frame = 1
Query:  241 NDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            +D     ++VGN+   + E ++ + FSQ GP  + K+I   +  +  + FV F     A  A+  MN  ++    +K N+A   +  K    N+  V+   L           E+T +     F  FG+I       ++     + Y F+SF    +A  AI    G  + G  I+  W   K     S    N K
Sbjct:    4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITE-HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSP---------EITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTK 189          
BLAST of Nucleolysin TIAR vs. Ensembl Mouse
Match: Tial1 (Tia1 cytotoxic granule-associated RNA binding protein-like 1 [Source:MGI Symbol;Acc:MGI:107913])

HSP 1 Score: 105.145 bits (261), Expect = 1.173e-25
Identity = 73/213 (34.27%), Postives = 105/213 (49.30%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP------LNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK         L ++ V N+S   N TV+  GI   LT QL    F  FG+I  I  FPE+ Y+F+ F+TH+ A  AI   +G  I G  +KCYWGK
Sbjct:   73 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGK 276          

HSP 2 Score: 48.9062 bits (115), Expect = 2.881e-6
Identity = 47/196 (23.98%), Postives = 78/196 (39.80%), Query Frame = 1
Query:  241 NDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            +D     ++VGN+   + E ++ + FSQ GP  + K+I   +  +  + FV F     A  A+  MN  ++    +K N+A   +  K    N+  V+   L           E+T +     F  FG+I       ++     + Y F+SF    +A  AI    G  + G  I+  W   K     S    N K
Sbjct:    4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITE-HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSP---------EITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTK 189          
BLAST of Nucleolysin TIAR vs. UniProt/SwissProt
Match: sp|P31483|TIA1_HUMAN (Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3)

HSP 1 Score: 108.612 bits (270), Expect = 4.248e-26
Identity = 80/258 (31.01%), Postives = 128/258 (49.61%), Query Frame = 1
Query:   28 GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAE--STPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            G C++C +++   G + +    ++ + H      ALA++    ++ ++V V +  TP ++   T    + S    ++   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L+YD V N+S  +N TV+  G+   LT QL    F  FG+I  I  FP++ Y+F+ F +H+ A  AI   +G  I G  +KCYWGK
Sbjct:   31 GPCKNCKMIMDTAGNDPYCFVEFHEHRHAA---AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGK 285          

HSP 2 Score: 58.151 bits (139), Expect = 1.936e-8
Identity = 51/199 (25.63%), Postives = 84/199 (42.21%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            + D     ++VGN+   + E ++ + FSQ GP  N K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    +  +V  +  + +  VFV  +  E+T +     F  FGRI       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K     S   +N K
Sbjct:    1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198          
BLAST of Nucleolysin TIAR vs. UniProt/SwissProt
Match: sp|P52912|TIA1_MOUSE (Nucleolysin TIA-1 OS=Mus musculus OX=10090 GN=Tia1 PE=1 SV=1)

HSP 1 Score: 107.457 bits (267), Expect = 1.123e-25
Identity = 79/258 (30.62%), Postives = 128/258 (49.61%), Query Frame = 1
Query:   28 GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAE--STPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            G C++C +++   G + +    ++ + H      ALA++    ++ ++V V +  TP ++   T    + S    ++   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A      PK         L+YD V ++S   N TV+  G+   LT QL    F  FG+I  I  FP++ Y+F+ F++H+ A  AI   +G  I G  +KCYWGK
Sbjct:   31 GPCKNCKMIMDTAGNDPYCFVEFHEHRHAA---AALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGK 285          

HSP 2 Score: 58.9214 bits (141), Expect = 1.156e-8
Identity = 51/199 (25.63%), Postives = 84/199 (42.21%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            + D     ++VGN+   + E ++ + FSQ GP  N K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    +  +V  +  + +  VFV  +  E+T +     F  FGRI       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K     S   +N K
Sbjct:    1 MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD-TAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTK 198          
BLAST of Nucleolysin TIAR vs. UniProt/SwissProt
Match: sp|Q01085|TIAR_HUMAN (Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 7.959e-25
Identity = 73/213 (34.27%), Postives = 105/213 (49.30%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP------LNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK         L ++ V N+S   N TV+  GI   LT QL    F  FG+I  I  FPE+ Y+F+ F+TH+ A  AI   +G  I G  +KCYWGK
Sbjct:   73 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGK 276          

HSP 2 Score: 50.8322 bits (120), Expect = 4.920e-6
Identity = 48/196 (24.49%), Postives = 79/196 (40.31%), Query Frame = 1
Query:  241 NDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDN------INNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            +D     ++VGN+   + E ++ + FSQ GP  + K+I   +  +  + FV F     A  A+  MN  ++    +K N+A   +  K    N+  V+   L           E+T +     F  FG+I +      +     + Y F+SF    +A  AI    G  + G  I+  W   K     S   NN K
Sbjct:    4 DDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITE-HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSP---------EITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTK 189          
BLAST of Nucleolysin TIAR vs. UniProt/SwissProt
Match: sp|P70318|TIAR_MOUSE (Nucleolysin TIAR OS=Mus musculus OX=10090 GN=Tial1 PE=1 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 8.728e-25
Identity = 73/213 (34.27%), Postives = 105/213 (49.30%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP------LNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK         L ++ V N+S   N TV+  GI   LT QL    F  FG+I  I  FPE+ Y+F+ F+TH+ A  AI   +G  I G  +KCYWGK
Sbjct:   90 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGK 293          
BLAST of Nucleolysin TIAR vs. UniProt/SwissProt
Match: sp|Q13310|PABP4_HUMAN (Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1)

HSP 1 Score: 79.337 bits (194), Expect = 2.003e-15
Identity = 49/176 (27.84%), Postives = 87/176 (49.43%), Query Frame = 1
Query:  247 RNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIPLNYDLVYNESLE--TNTTVFVSGIELTI--QLWTFYFKTFGRIDN----INNFPERKYAFISFATHKEATKAICQRHGYIINGTAI 747
            +    V++ N G  +++  LKE FSQFG  L+VKV+R PN  SKGF FVS+     A KA++ MN   +   II    A   +     +   ++ +  E +       +++  ++ TI  +     F  FG I +    + +   + + F+ F++ +EATKA+ + +G I+    +
Sbjct:  188 KEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPL 363          

HSP 2 Score: 57.7658 bits (138), Expect = 3.543e-8
Identity = 55/205 (26.83%), Postives = 93/205 (45.37%), Query Frame = 1
Query:  199 IAESTPIR-----KIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDNIN-----NFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQ 783
            + +  PIR     + PS +    +  VF+ N+   I+   L + FS FG +L+ KV+   N  SKG+AFV F     A KAI+ MN   L++  +   F       K      +L       TN  +   G E+  +     F  FG+  ++      N   + + F+S+  H++A KA+ + +G  I+G  I  + G+ +K  +
Sbjct:   76 VIKGKPIRIMWSQRDPS-LRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQEAADKAIEKMNGMLLNDRKV---FVGRFKSRKE--REAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKII--FVGRAQKKVE 271          
BLAST of Nucleolysin TIAR vs. TrEMBL
Match: D5JG77 (TIA1-like protein OS=Dugesia japonica OX=6161 GN=TIAL-3 PE=2 SV=1)

HSP 1 Score: 202.601 bits (514), Expect = 4.620e-60
Identity = 108/252 (42.86%), Postives = 158/252 (62.70%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGP---KHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            FG C  C+++  F    + Y   +  Y  ++    AL+++  + M + Q+ V +   P A   P     + I+  N V++FVG+IGL ++E MLKE FSQFG +++ KV+R+P+  S+GFAFVSFSN   A +AI +M++T  HN  IKCN+A   G+ G    K+ P  Y+LVY E+  TNT V+V+G  LT +L   +F+ FGRID++  +PE+ +AFI+F TH+ A +AI QRHGY IN   IKC WGK
Sbjct:   30 FGQCISCHIIRDFSCQTNPYA--FIEYTDHSSASLALSAMDGIYMWNNQIKVNWSSGPSAVPGPAAVASAKIDYSNSVQIFVGDIGLDVDEPMLKEGFSQFGQLIDAKVVRYPDGQSRGFAFVSFSNRDEAERAIQSMHKTWFHNRTIKCNWATRNGLDGEQFIKYTPRPYELVYKEAPLTNTNVYVAGENLTEELLNCHFQEFGRIDSVKVYPEKGHAFINFVTHEAAARAISQRHGYKINDNVIKCNWGK 279          

HSP 2 Score: 65.855 bits (159), Expect = 1.083e-8
Identity = 48/182 (26.37%), Postives = 91/182 (50.00%), Query Frame = 1
Query:  247 RNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALG---ITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQ--LWTFYFKTFGRI--DNINNFPE---RKYAFISFATHKEATKAICQRHGYIINGTAIKCYWG 762
            +N   ++VGN+   +N+ +L   F  FG  ++  +IR  +  +  +AF+ +++ S A+ A+  M+   + N  IK N++ G   + GP  +  +  + Y+ S++    +FV  I L +   +    F  FG++    +  +P+   R +AF+SF+   EA +AI   H    +   IKC W 
Sbjct:    4 KNNRTIYVGNLPDAVNDQLLIRIFGNFGQCISCHIIRDFSCQTNPYAFIEYTDHSSASLALSAMDGIYMWNNQIKVNWSSGPSAVPGPAAV-ASAKIDYSNSVQ----IFVGDIGLDVDEPMLKEGFSQFGQLIDAKVVRYPDGQSRGFAFVSFSNRDEAERAIQSMHKTWFHNRTIKCNWA 180          
BLAST of Nucleolysin TIAR vs. TrEMBL
Match: D5JG78 (TIA1-like protein (Fragment) OS=Dugesia japonica OX=6161 GN=TIAL-4 PE=2 SV=1)

HSP 1 Score: 182.185 bits (461), Expect = 1.405e-52
Identity = 107/256 (41.80%), Postives = 162/256 (63.28%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSN--INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGP---KHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            FG C  C+++  F    + Y   +  Y +++    ALA++  + M + Q+ V +  +  + +T    +PS+  I+  N +++FVG+IGL ++E MLKE FS+FGPV++ KV+R+ +  S+GFAFV+FS    A KAI+ M++T  HN  IKCN+A   G+ G    K+ P  Y+LVY E+  TNT V+++GI   LT +L   +F+ FGRID +  +PE+ +AFI+F TH+ A +AI QRHGY IN   IKC WGK
Sbjct:   30 FGQCVGCHIIRDFSCQTNPY--AFIEYTNHSAASLALAAMDGIFMWNNQIKVNWS-SGNSVNTVASSLPSSNKIDYSNTIQIFVGDIGLDVDEAMLKEGFSEFGPVVDAKVVRYQDGQSRGFAFVAFSKRDDAEKAIEKMHKTWFHNRTIKCNWATRNGLDGDQFIKYTPRPYELVYKEAPLTNTNVYIAGIPEGLTEELIRVHFEEFGRIDAVKVYPEKAHAFINFVTHESAARAISQRHGYKINDNVIKCNWGK 282          
BLAST of Nucleolysin TIAR vs. TrEMBL
Match: D5JG75 (TIA1-like protein (Fragment) OS=Dugesia japonica OX=6161 GN=TIAL-1 PE=2 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 6.006e-37
Identity = 82/192 (42.71%), Postives = 110/192 (57.29%), Query Frame = 1
Query:  256 VRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLN------------YDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDN 795
            V++FVG IG  I+E +LKE F+  G VL+ KV+R  +   KGFAFVSFSN S A  AI  MN T  HN  I+CN+A         P N             D+ Y E+ E+NT+V+V G  LT +L    F+ FG+I N+  FPE+ +AF+++ TH  A  AI Q +GY IN   +KC WGK      N++N
Sbjct:   95 VQIFVGGIGFDIDEAILKEGFAHCGQVLDTKVVRSNDGQHKGFAFVSFSNESDANSAIQKMNNTMFHNRKIQCNWATKNKNSNGAPFNPKFNPTKFNKTLEDISY-EAPESNTSVYVLGESLTEELLRPIFERFGKIKNVKAFPEKNHAFVNYDTHDAAAYAIQQLNGYKINNIELKCNWGKKNAALGNANN 285          
BLAST of Nucleolysin TIAR vs. TrEMBL
Match: A0A2H8TUQ6 (Nucleolysin TIAR OS=Melanaphis sacchari OX=742174 GN=TIAL1_4 PE=4 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 5.557e-31
Identity = 82/229 (35.81%), Postives = 121/229 (52.84%), Query Frame = 1
Query:  112 NTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIP--------LNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            ++G   ALA++     LD+++ V +  TP  +          ++  N   +FVG++   I  + LKEAF+ FG + N +++R P  + SKG+AFVSF   S A  AI++MN   L +  I+ N++     P   P        + +D VYN+S  TN TV+  GI   LT +L    F  FG I  I  F ++ YAFI F+T + AT AI   H   ING  +KC+WGK
Sbjct:   56 HSGAATALAAMNGRLFLDKEMKVNWATTPGNQP--------KLDTSNHYHIFVGDLSPEIETHTLKEAFAPFGEISNCRIVRDPQTLKSKGYAFVSFVKKSDAENAINSMNGQWLGSRSIRTNWSTRKPPPPRAPNKYSGYRAVTFDDVYNQSSPTNCTVYCGGIVEGLTEELVEQVFSRFGTIVEIRAFRDKGYAFIKFSTKEAATTAIEAVHNTEINGHPVKCFWGK 276          

HSP 2 Score: 61.2326 bits (147), Expect = 5.883e-7
Identity = 53/187 (28.34%), Postives = 80/187 (42.78%), Query Frame = 1
Query:  241 NDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNT--TVFVSGIELTIQLWTF--YFKTFGRIDNI------NNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGK 771
            ++ N   ++VGN+   + E +L   F+  GPV   KVIR P   S  +AF+ F   S A  A+  MN     +  +K N+A   T P + P          L+T+    +FV  +   I+  T    F  FG I N            + YAF+SF    +A  AI   +G  +   +I+  W   K
Sbjct:    3 DESNPRTLYVGNLDPSVTEELLCALFTNIGPVNACKVIREPG--SDPYAFLEFDTHSGAATALAAMNGRLFLDKEMKVNWA---TTPGNQP---------KLDTSNHYHIFVGDLSPEIETHTLKEAFAPFGEISNCRIVRDPQTLKSKGYAFVSFVKKSDAENAINSMNGQWLGSRSIRTNWSTRK 175          
BLAST of Nucleolysin TIAR vs. TrEMBL
Match: A0A2S2PKR1 (Nucleolysin TIAR OS=Schizaphis graminum OX=13262 GN=TIAL1_1 PE=4 SV=1)

HSP 1 Score: 128.642 bits (322), Expect = 5.557e-31
Identity = 82/229 (35.81%), Postives = 121/229 (52.84%), Query Frame = 1
Query:  112 NTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIP--------LNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            ++G   ALA++     LD+++ V +  TP  +          ++  N   +FVG++   I  + LKEAF+ FG + N +++R P  + SKG+AFVSF   S A  AI++MN   L +  I+ N++     P   P        + +D VYN+S  TN TV+  GI   LT +L    F  FG I  I  F ++ YAFI F+T + AT AI   H   ING  +KC+WGK
Sbjct:   56 HSGAATALAAMNGRLFLDKEMKVNWATTPGNQP--------KLDTSNHYHIFVGDLSPEIETHTLKEAFAPFGEISNCRIVRDPQTLKSKGYAFVSFVKKSDAENAINSMNGQWLGSRSIRTNWSTRKPPPPRAPNKYSGYRAVTFDDVYNQSSPTNCTVYCGGIVEGLTEELVEQVFSRFGTIVEIRAFRDKGYAFIKFSTKEAATTAIEAVHNTEINGHPVKCFWGK 276          

HSP 2 Score: 61.2326 bits (147), Expect = 5.883e-7
Identity = 53/187 (28.34%), Postives = 80/187 (42.78%), Query Frame = 1
Query:  241 NDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNT--TVFVSGIELTIQLWTF--YFKTFGRIDNI------NNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGK 771
            ++ N   ++VGN+   + E +L   F+  GPV   KVIR P   S  +AF+ F   S A  A+  MN     +  +K N+A   T P + P          L+T+    +FV  +   I+  T    F  FG I N            + YAF+SF    +A  AI   +G  +   +I+  W   K
Sbjct:    3 DESNPRTLYVGNLDPSVTEELLCALFTNIGPVNACKVIREPG--SDPYAFLEFDTHSGAATALAAMNGRLFLDKEMKVNWA---TTPGNQP---------KLDTSNHYHIFVGDLSPEIETHTLKEAFAPFGEISNCRIVRDPQTLKSKGYAFVSFVKKSDAENAINSMNGQWLGSRSIRTNWSTRK 175          
BLAST of Nucleolysin TIAR vs. Ensembl Cavefish
Match: tia1l (TIA1 cytotoxic granule associated RNA binding protein [Source:NCBI gene;Acc:103030565])

HSP 1 Score: 107.842 bits (268), Expect = 5.042e-27
Identity = 81/265 (30.57%), Postives = 128/265 (48.30%), Query Frame = 1
Query:   19 QIF---GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGI---------TG-PKHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            Q+F   G C+ C ++I   G + +    +Y + H      AL ++    +L + + V +   P ++           +  N   VFVG++   I+   +K AF+ FG + + +V++      SKG+ F+SF N   A  AI  MN   L    I+ N+A            TG  KH  L+Y+ V ++S  +N TV+  G+   LT QL    F  FG+I  I  FP++ Y+F+ F +H+ A  AI   +G  I G  +KCYWGK
Sbjct:   26 QVFTQIGPCKSCKMIIDTAGNDPYCFVEFYEHMHAAA---ALGAMNGRKILGKDMKVNWASMPSSQKK---------DTSNHFHVFVGDLSPEISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNWATRKPPAPKSNYETGNTKH--LSYEEVLSQSSPSNCTVYCGGVTSGLTDQLMRQTFSPFGQIMEIRVFPDKGYSFVRFDSHEGAAHAIVSVNGTCIEGHTVKCYWGK 276          

HSP 2 Score: 50.0618 bits (118), Expect = 9.197e-7
Identity = 44/184 (23.91%), Postives = 76/184 (41.30%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDN------INNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGK 771
            ++D     ++VGN+   + E ++ + F+Q GP  + K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    N+  V+   L           E++       F  FG+I +      +     + Y FISF    +A  AI Q +G  + G  I+  W   K
Sbjct:    2 MDDDQPKTLYVGNLSRDVTEALILQVFTQIGPCKSCKMIID-TAGNDPYCFVEFYEHMHAAAALGAMNGRKILGKDMKVNWASMPSSQKKDTSNHFHVFVGDLSP---------EISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNWATRK 175          
BLAST of Nucleolysin TIAR vs. Ensembl Cavefish
Match: tia1l (TIA1 cytotoxic granule associated RNA binding protein [Source:NCBI gene;Acc:103030565])

HSP 1 Score: 107.842 bits (268), Expect = 5.042e-27
Identity = 81/265 (30.57%), Postives = 128/265 (48.30%), Query Frame = 1
Query:   19 QIF---GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGI---------TG-PKHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            Q+F   G C+ C ++I   G + +    +Y + H      AL ++    +L + + V +   P ++           +  N   VFVG++   I+   +K AF+ FG + + +V++      SKG+ F+SF N   A  AI  MN   L    I+ N+A            TG  KH  L+Y+ V ++S  +N TV+  G+   LT QL    F  FG+I  I  FP++ Y+F+ F +H+ A  AI   +G  I G  +KCYWGK
Sbjct:   26 QVFTQIGPCKSCKMIIDTAGNDPYCFVEFYEHMHAAA---ALGAMNGRKILGKDMKVNWASMPSSQKK---------DTSNHFHVFVGDLSPEISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNWATRKPPAPKSNYETGNTKH--LSYEEVLSQSSPSNCTVYCGGVTSGLTDQLMRQTFSPFGQIMEIRVFPDKGYSFVRFDSHEGAAHAIVSVNGTCIEGHTVKCYWGK 276          

HSP 2 Score: 50.0618 bits (118), Expect = 9.197e-7
Identity = 44/184 (23.91%), Postives = 76/184 (41.30%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDN------INNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGK 771
            ++D     ++VGN+   + E ++ + F+Q GP  + K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    N+  V+   L           E++       F  FG+I +      +     + Y FISF    +A  AI Q +G  + G  I+  W   K
Sbjct:    2 MDDDQPKTLYVGNLSRDVTEALILQVFTQIGPCKSCKMIID-TAGNDPYCFVEFYEHMHAAAALGAMNGRKILGKDMKVNWASMPSSQKKDTSNHFHVFVGDLSP---------EISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNWATRK 175          
BLAST of Nucleolysin TIAR vs. Ensembl Cavefish
Match: tial1 (TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:NCBI gene;Acc:103030475])

HSP 1 Score: 95.1301 bits (235), Expect = 3.856e-22
Identity = 69/220 (31.36%), Postives = 105/220 (47.73%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP-------------LNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I    ++ AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK +              L ++ V N+S   N TV+  GI+  L+  L    F  FG+I  I  FPE+ Y+FI F++H+ A  AI   +G  I    +KCYWGK
Sbjct:   72 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDSKQIAHLGSSKQLRFEDVVNQSSPQNCTVYCGGIQSGLSEHLIRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIESHIVKCYWGK 282          
BLAST of Nucleolysin TIAR vs. Ensembl Cavefish
Match: tia1l (TIA1 cytotoxic granule associated RNA binding protein [Source:NCBI gene;Acc:103030565])

HSP 1 Score: 78.5666 bits (192), Expect = 1.499e-16
Identity = 65/233 (27.90%), Postives = 109/233 (46.78%), Query Frame = 1
Query:   19 QIF---GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGI---------TGPKHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFI 672
            Q+F   G C+ C ++I   G + +    +Y + H      AL ++    +L + + V +   P ++           +  N   VFVG++   I+   +K AF+ FG + + +V++      SKG+ F+SF N   A  AI  MN   L    I+ N+A            +  KH  L+Y+ V ++S  +N TV+  G+   LT QL    F  FG+I  I  FP++ Y+F+
Sbjct:   25 QVFTQIGPCKSCKMIIDTAGNDPYCFVEFYEHMHAAA---ALGAMNGRKILGKDMKVNWASMPSSQKK---------DTSNHFHVFVGDLSPEISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNWATRKPPAPKSNYESNTKH--LSYEEVLSQSSPSNCTVYCGGVTSGLTDQLMRQTFSPFGQIMEIRVFPDKGYSFV 243          

HSP 2 Score: 53.1434 bits (126), Expect = 7.625e-8
Identity = 47/197 (23.86%), Postives = 81/197 (41.12%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDN------INNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            ++D     ++VGN+   + E ++ + F+Q GP  + K+I      +  + FV F     A  A+  MN  ++    +K N+A   +  K    N+  V+   L           E++       F  FG+I +      +     + Y FISF    +A  AI Q +G  + G  I+  W   K     S+  +N K
Sbjct:    1 MDDDQPKTLYVGNLSRDVTEALILQVFTQIGPCKSCKMIID-TAGNDPYCFVEFYEHMHAAAALGAMNGRKILGKDMKVNWASMPSSQKKDTSNHFHVFVGDLSP---------EISTDDVKAAFAPFGKISDARVVKDLATGKSKGYGFISFINKWDAENAIQQMNGQWLGGRQIRTNWATRKPPAPKSNYESNTK 187          
BLAST of Nucleolysin TIAR vs. Ensembl Cavefish
Match: ENSAMXT00000035946.1 (polyadenylate-binding protein 1-like [Source:NCBI gene;Acc:103030422])

HSP 1 Score: 67.0106 bits (162), Expect = 2.990e-12
Identity = 46/187 (24.60%), Postives = 84/187 (44.92%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTI---------QLWTFYFKTFGRIDNINNFPE----RKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQ 783
            V++ N G  +++  LK+ F ++GP L+++V+   +  SKGF FVSF     A +A+D MN   L+   +    A    G +   L       E ++ +      G+ L +         +     F  FG I +     E    + + F+ F++ +EATKA+ + +G I+    +     + K+  Q
Sbjct:  193 VYIKNFGEDMDDEKLKDVFGKYGPALSIRVMTDESGKSKGFGFVSFERHEDAQRAVDEMNGKELNGKQVYVGRAQK-KGERQTELKRKF---EQMKQDRMTRYQGVNLYVKNLDDGLDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQ 375          

HSP 2 Score: 56.6102 bits (135), Expect = 1.014e-8
Identity = 43/172 (25.00%), Postives = 82/172 (47.67%), Query Frame = 1
Query:  253 IVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFY--FKTFGRIDN----INNFPERKYAFISFATHKEATKAICQRHGYIINGTAI 747
            +  ++VG++   + E ML E FS  GP+L+++V R    + S G+A+V+F   + A +A+D MN   +    ++  ++             D    +S   N  +F+  ++ +I     Y  F  FG I +     +    + Y F+ F TH+ A +AI + +G ++N   +
Sbjct:   10 MASLYVGDLHQDVTEAMLYEKFSPAGPILSIRVCRDMMTRRSLGYAYVNFQQPADAERALDTMNFDVIKGRPVRIMWS-----------QRDPSLRKSGVGN--IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETHEAAERAIEKMNGMLLNDRKV 168          
BLAST of Nucleolysin TIAR vs. Ensembl Sea Lamprey
Match: tia1l (cytotoxic granule-associated RNA binding protein 1, like [Source:ZFIN;Acc:ZDB-GENE-030131-2167])

HSP 1 Score: 106.301 bits (264), Expect = 7.055e-28
Identity = 69/180 (38.33%), Postives = 96/180 (53.33%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL---------GITGPKHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            VFVG++   I+   L+ AF+ FG + + +V++      SKG+ FVSF     A  AI  M    L    I+ N+A            T PKH  L+++ V N+S  TN TV+  GI   LT QL    F  FG+I  I  FP++ Y+FI FATH+ A  AI   +G  I G ++KC+WGK
Sbjct:    5 VFVGDLSPEISTDDLRAAFAPFGKISDARVVKDLATGKSKGYGFVSFFQKLDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKGSQDTDPKH--LSFEEVLNQSSPTNCTVYCGGITQGLTEQLMRQTFLLFGQILEIRVFPDKGYSFIRFATHESAAHAIVSVNGSTIEGFSVKCFWGK 182          
BLAST of Nucleolysin TIAR vs. Ensembl Sea Lamprey
Match: pabpc4 (poly(A) binding protein, cytoplasmic 4 (inducible form) [Source:ZFIN;Acc:ZDB-GENE-030131-9663])

HSP 1 Score: 68.9366 bits (167), Expect = 1.286e-13
Identity = 51/178 (28.65%), Postives = 84/178 (47.19%), Query Frame = 1
Query:  247 RNIVRVFVGNIGLRINEYMLKEAFSQF-GPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPK-HIPLNYDLVYNESLE--TNTTVFVSGIELTI---QLWTFYFKTFGRIDNINNFPE----RKYAFISFATHKEATKAICQRHGYIINGTAI 747
            R    V++ N G  +++  L+E F Q+ G  L+VKV+      SKGF FVSF     A KA+D MN   L+   I    A      +  +   ++++  E +       ++V  ++  I   +LW   F  FG I +     E    R + F+ F++ +EATKA+ + +G II    +
Sbjct:   48 REFTNVYIKNFGDDMDDERLREYFEQYVGKTLSVKVMMDEGGKSKGFGFVSFERHEDAQKAVDEMNTKELNGRAIYVGRAQKKAERQTELKRKFEMLKQERMSKYQGVNLYVKNLDDNINDERLWK-EFSPFGTITSAKVMMEEGRSRGFGFVCFSSPEEATKAVTEMNGRIIGSKPL 224          
BLAST of Nucleolysin TIAR vs. Ensembl Sea Lamprey
Match: pabpc4 (poly(A) binding protein, cytoplasmic 4 (inducible form) [Source:ZFIN;Acc:ZDB-GENE-030131-9663])

HSP 1 Score: 58.151 bits (139), Expect = 4.929e-10
Identity = 43/172 (25.00%), Postives = 81/172 (47.09%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPL--NYDLVYNESLE--TNTTVFVSGIELTI--QLWTFYFKTFGRIDNINNFPE----RKYAFISFATHKEATKAICQRHGYIINGTAI 747
            V++ N G  ++E  L+E F +FG  L+V V+      S+GF FVSF     A +A++ MN   L+   +    A    G +   L   ++++  E +       ++V  ++  I  +     F  +G I +     E    + + F+ F++ +EATKA+ + +G I+    +
Sbjct:  196 VYIKNFGDDMDEDKLREFFGKFGKALSVCVMSDECGKSRGFGFVSFEQHEDAQRAVNEMNGKELNGRTVFVGRAQK-KGERQAELKRKFEMLKQERISRYQGVNLYVKNLDDNIDDEQLRKEFAPYGTITSTKVMSEEGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPL 366          

HSP 2 Score: 57.7658 bits (138), Expect = 7.375e-10
Identity = 44/176 (25.00%), Postives = 81/176 (46.02%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDNINNFPE-----RKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKK 774
            VF+ N+   I+   + + FS FG +L+ KV+   N  S+G+ FV F     A +AI+ MN   L++ + +  F       K           E   TN  +   G ++       +F  FG+  ++    +     R + F+SF  H++A +A+ + +G  +NG  +  + G+ +K
Sbjct:  101 VFIKNLDKSIDNKAMYDTFSAFGNILSCKVVCDENG-SRGYGFVHFETQEAADRAIEKMNGMLLNDRLARRRFVGRFKSRKEREQEMGARAKEF--TNVYIKNFGDDMDEDKLREFFGKFGKALSVCVMSDECGKSRGFGFVSFEQHEDAQRAVNEMNGKELNGRTV--FVGRAQK 271          

HSP 3 Score: 56.6102 bits (135), Expect = 1.790e-9
Identity = 46/168 (27.38%), Postives = 80/168 (47.62%), Query Frame = 1
Query:  253 IVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHP-NKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFY--FKTFGRIDN----INNFPERKYAFISFATHKEATKAICQRHGYIIN 735
            +  ++VG++   + E ML E FS  GPVL+++V R    + S G+A+V+F   + A +A+D MN   +    I+  ++             D    +S   N  VF+  ++ +I     Y  F  FG I +     +    R Y F+ F T + A +AI + +G ++N
Sbjct:   10 MASLYVGDLHPDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWS-----------QRDPSLRKSGVGN--VFIKNLDKSIDNKAMYDTFSAFGNILSCKVVCDENGSRGYGFVHFETQEAADRAIEKMNGMLLN 164          
BLAST of Nucleolysin TIAR vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004893.1 (pep scaffold:Pmarinus_7.0:GL479484:4:2056:-1 gene:ENSPMAG00000004449.1 transcript:ENSPMAT00000004893.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.6102 bits (135), Expect = 6.381e-10
Identity = 44/169 (26.04%), Postives = 80/169 (47.34%), Query Frame = 1
Query:  259 RVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRIDNINNFPERK------YAFISFATHKEATKAICQRHGYIING 738
            ++FVG +     E  L++ F Q+G + +  V++   +K S+GF FV+FS++S     +D     R H    +      +  PK      D +   +  +   +FV GI  +   +    YF+ +GRI+ +    ER+      +AF++F  H    K + Q++ + ING
Sbjct:   12 KLFVGGLSFETTEEGLRQYFEQWGSLTDCVVMKDTQSKRSRGFGFVTFSSMS----EVDAAMSARPHKIDGR------MVEPKRAVSREDSMRPGAHLSVKKIFVGGIKDDTDEEHLRDYFEKYGRIEIVEVMTERESGKKRGFAFVTFNDHDPVDKIVVQKY-HTING 169          
BLAST of Nucleolysin TIAR vs. Ensembl Sea Lamprey
Match: sf3b4 (splicing factor 3b, subunit 4 [Source:ZFIN;Acc:ZDB-GENE-020419-22])

HSP 1 Score: 56.6102 bits (135), Expect = 1.658e-9
Identity = 51/180 (28.33%), Postives = 85/180 (47.22%), Query Frame = 1
Query:  238 INDRNI-VRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKIS---KGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFY--FKTFGRI---DNINNFPE----RKYAFISFATHKEATKAICQRHG-YIIN 735
            I++RN    V+VG +  +++E +L E F Q GPV+N  + +  ++I+   +G+ FV F     A  AI  MN  +L+   I+ N A                +N++L+    +F+  ++  I     Y  F  FG I         PE    + YAFI+FA+ + +  AI   +G Y+ N
Sbjct:    6 ISERNQDATVYVGGLDDKVSEALLWELFLQAGPVVNTHMPK--DRITQQHQGYGFVEFLGEEDADYAIKIMNMIKLYGKPIRVNKA--------------SAHNKNLDVGANIFIGNLDTEIDEKLLYDTFSAFGVILQTPKTMRDPETGNSKGYAFINFASFEASDAAIEAMNGQYLCN 169          

HSP 2 Score: 51.6026 bits (122), Expect = 6.003e-8
Identity = 32/95 (33.68%), Postives = 55/95 (57.89%), Query Frame = 1
Query:  214 PIRKIPSNINDRNI---VRVFVGNIGLRINEYMLKEAFSQFGPVLNV-KVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFA 483
            PIR   ++ +++N+     +F+GN+   I+E +L + FS FG +L   K +R P    SKG+AF++F++   +  AI+ MN   L N  I  ++A
Sbjct:   83 PIRVNKASAHNKNLDVGANIFIGNLDTEIDEKLLYDTFSAFGVILQTPKTMRDPETGNSKGYAFINFASFEASDAAIEAMNGQYLCNRPISVSYA 177          
BLAST of Nucleolysin TIAR vs. Ensembl Yeast
Match: PUB1 (Poly (A)+ RNA-binding protein; abundant mRNP-component protein that binds mRNA and is required for stability of many mRNAs; component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; implicated in regulation of translation; carries Q/N-rich domain at C- terminus, identified as candidate prion; human homolog Tia1 is critical for normal synaptic plasticity; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004961])

HSP 1 Score: 60.077 bits (144), Expect = 6.950e-11
Identity = 48/199 (24.12%), Postives = 84/199 (42.21%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTF--YFKTF-----GRID-NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKK-------YTQNSDNNNNRKG 813
            ++VGN+   I E +LK+ F   GP+ N+K++   N  +  +AFV +     A  A+  +N  ++ N I+K N+A                   S +    +FV  + + +   T    FK F     G +  ++     R Y F+SF +  +A  A+    G  +NG  ++  W   +          + +  NNNR G
Sbjct:   77 LYVGNLDKAITEDILKQYFQVGGPIANIKIMIDKNNKNVNYAFVEYHQSHDANIALQTLNGKQIENNIVKINWAF-------------QSQQSSSDDTFNLFVGDLNVNVDDETLRNAFKDFPSYLSGHVMWDMQTGSSRGYGFVSFTSQDDAQNAMDSMQGQDLNGRPLRINWAAKRDNNNNNNYQQRRNYGNNNRGG 262          
BLAST of Nucleolysin TIAR vs. Ensembl Yeast
Match: PAB1 (Poly(A) binding protein; part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G; stimulates, but is not required for the deadenylation activity of the Pan2p-Pan3p poly(A)-ribonuclease complex [Source:SGD;Acc:S000000967])

HSP 1 Score: 56.9954 bits (136), Expect = 8.959e-10
Identity = 48/178 (26.97%), Postives = 78/178 (43.82%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRI-----DNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKK 774
            +F+ N+   I+   L + FS FG +L+ K+    N  SKGF FV F     A +AID +N   L+   I          P       D    E+    T ++V  I  E T + +   F  FG I     +   +   + + F+++  H++A KA+   +   +NG   K Y G+ +K
Sbjct:  128 IFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEI-------YVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGE--KLYVGRAQK 296          

HSP 2 Score: 53.1434 bits (126), Expect = 1.640e-8
Identity = 27/63 (42.86%), Postives = 38/63 (60.32%), Query Frame = 1
Query:  256 VRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQ 444
            V +FV N+   +++  L+E F+ +G + + KV+R  N  SKGF FV FS    ATKAI   NQ
Sbjct:  322 VNLFVKNLDDSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQ 384          

HSP 3 Score: 45.0542 bits (105), Expect = 6.125e-6
Identity = 42/172 (24.42%), Postives = 73/172 (42.44%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHP-NKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTT--VFVSGIELTIQLWTFY--FKTFG-----RIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAI 747
            ++VG++   ++E  L + FS  G V +++V R    K S G+A+V+F++     KAI+ +N T +   +  C        P             SL    +  +F+  +   I     Y  F  FG     +I    N   + + F+ F     A +AI   +G ++NG  I
Sbjct:   40 LYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGRKAIEQLNYTPIKGRL--CRIMWSQRDP-------------SLRKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEI 196          
BLAST of Nucleolysin TIAR vs. Ensembl Yeast
Match: HSH49 (U2-snRNP associated splicing factor; similar to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM) [Source:SGD;Acc:S000005846])

HSP 1 Score: 50.0618 bits (118), Expect = 7.188e-8
Identity = 34/88 (38.64%), Postives = 47/88 (53.41%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPN-KISKGFAFVSFSNLSIATKAIDNMNQT-RLHNCIIKCNFALGITGPKHIPLN 519
            V+VGNI  RI +  L E F Q  PVL +K  +    +  +G+AF+ F N   A  AI  MN T RL++ +IK       TG  ++P N
Sbjct:   11 VYVGNIDPRITKEQLYELFIQINPVLRIKYPKDKVLQAYQGYAFIEFYNQGDAQYAIKIMNNTVRLYDRLIKVRQVTNSTGTTNLPSN 98          
BLAST of Nucleolysin TIAR vs. Ensembl Yeast
Match: NSR1 (Nucleolar protein that binds nuclear localization sequences; required for pre-rRNA processing and ribosome biogenesis; binds to single stranded telomeric DNA and mRNA; methylated by Hmt1p; interaction with Top1p and nucleolar localization are negatively regulated by polyphosphorylation [Source:SGD;Acc:S000003391])

HSP 1 Score: 49.2914 bits (116), Expect = 2.456e-7
Identity = 23/75 (30.67%), Postives = 44/75 (58.67%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPN-KISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFA 483
            +F+GN+    +   + E F++ G V++V++  HP  +  KGF +V FSN+  A KA+D +    + N  ++ +F+
Sbjct:  269 LFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEYIDNRPVRLDFS 343          

HSP 2 Score: 48.1358 bits (113), Expect = 5.307e-7
Identity = 38/172 (22.09%), Postives = 72/172 (41.86%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVI-RHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFY--FKTFGRIDNIN--NFPE----RKYAFISFATHKEATKAICQRHGYIINGTAIK 750
            +FVG +   I++  LK+ F   G V+  +VI       S+G+ +V F N S A KAI  M    +    I C+  +  + P           +   E + T+F+  +         +  F   G + ++     PE    + + ++ F+  ++A KA+    G  I+   ++
Sbjct:  170 IFVGRLSWSIDDEWLKKEFEHIGGVIGARVIYERGTDRSRGYGYVDFENKSYAEKAIQEMQGKEIDGRPINCD--MSTSKPAGNNDRAKKFGDTPSEPSDTLFLGNLSFNADRDAIFELFAKHGEVVSVRIPTHPETEQPKGFGYVQFSNMEDAKKALDALQGEYIDNRPVR 339          
BLAST of Nucleolysin TIAR vs. Ensembl Yeast
Match: RNA15 (Component of the cleavage and polyadenylation factor I (CF I); CF 1, composed of the CF 1A complex (Rna14p, Rna15p, Clp1p, Pcf11p) and Hrp1, is involved in cleavage and polyadenylation of mRNA 3' ends; interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay; required for gene looping and maintenance of genome stability [Source:SGD;Acc:S000003012])

HSP 1 Score: 46.9802 bits (110), Expect = 1.070e-6
Identity = 24/75 (32.00%), Postives = 44/75 (58.67%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNK-ISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFA 483
            V++G+I     E  + +  S  GPV+N+K++  P    SKG+AF+ F +L  +  A+ N+N  +L +  +KC ++
Sbjct:   20 VYLGSIPYDQTEEQILDLCSNVGPVINLKMMFDPQTGRSKGYAFIEFRDLESSASAVRNLNGYQLGSRFLKCGYS 94          
BLAST of Nucleolysin TIAR vs. Ensembl Nematostella
Match: EDO32492 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUY1])

HSP 1 Score: 72.7886 bits (177), Expect = 2.723e-15
Identity = 46/151 (30.46%), Postives = 75/151 (49.67%), Query Frame = 1
Query:  250 NIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNK-ISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIP------LNYDLVYNESLETNTTVFVSGIELTIQLWTF--YFKTFGRIDNINNFPERKYAFIS 675
            N   +FVG++   ++  +L++ F  FG +  V+V++ P K  SKGF FVSF     A KAI  M+   +    +K N+A     P          L +D V+++S + NTTV+V  +   ++ +     F  +G I     F ++ YAFI 
Sbjct:   85 NHFHIFVGDLAENVDNALLRKTFEPFGEISEVRVVKDPAKNKSKGFGFVSFVRREDAAKAIAEMDSVTIGGKQVKTNWAARKNNPTQSKYVCVKNLLWDDVFHQSSQLNTTVYVGNLPPDVKDYELQQMFSQYGSILETKVFADKGYAFIK 235          

HSP 2 Score: 45.0542 bits (105), Expect = 9.890e-6
Identity = 43/179 (24.02%), Postives = 76/179 (42.46%), Query Frame = 1
Query:  265 FVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKIS-KG-FAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQ--LWTFYFKTFGRIDNINNFPE------RKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGK 771
            +VGN+  +  + ++   F++   V+  K+I   N +S KG + FV F   + A +A   M+Q  + +  +K N+A    G K    N           +  +FV  +   +   L    F+ FG I  +    +      + + F+SF   ++A KAI +     I G  +K  W   K
Sbjct:    1 YVGNLDPKCTQELICSIFNKIAKVVRCKMI---NSVSYKGPYCFVEFETHADAQEAKFRMDQRTVMDKKLKVNWATNHPGMKRGDTN----------NHFHIFVGDLAENVDNALLRKTFEPFGEISEVRVVKDPAKNKSKGFGFVSFVRREDAAKAIAEMDSVTIGGKQVKTNWAARK 166          
BLAST of Nucleolysin TIAR vs. Ensembl Nematostella
Match: EDO33206 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSV8])

HSP 1 Score: 53.5286 bits (127), Expect = 3.473e-8
Identity = 48/175 (27.43%), Postives = 76/175 (43.43%), Query Frame = 1
Query:  253 IVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFY--FKTFGRI-------DNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAI 747
            I  ++VG++   + E ML E FS  G VL+++V R    + S G+A+V+F     A KA+D MN   +      C        P    L    V N        +F+  ++ +I   + Y  F  FG I       D + N   + Y F+ F T   A +AI +  G ++N   +
Sbjct:   12 IASLYVGDLAPDVTEAMLYEKFSTAGSVLSIRVCRDLVTRRSLGYAYVNFQQPGHAEKALDTMNFDPIKGR--PCRIMWQQRDPS---LRKSGVGN--------IFIKNLDKSIDNKSLYDTFSAFGNILSCKIAQDELGN--PKGYGFVHFETEDAALEAIARVDGMLLNDKKV 171          

HSP 2 Score: 49.6766 bits (117), Expect = 6.666e-7
Identity = 27/74 (36.49%), Postives = 42/74 (56.76%), Query Frame = 1
Query:  220 RKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMN 441
            +K    IN    V +++ N+   I++  L+E FS +G + + KV++     SKGF FV FS+   ATKA+  MN
Sbjct:  285 KKRQERINRFQGVNLYIKNLDDPIDDERLREEFSPYGTISSAKVMKDDKGNSKGFGFVCFSSPEEATKAVTEMN 358          

HSP 3 Score: 48.521 bits (114), Expect = 1.385e-6
Identity = 37/168 (22.02%), Postives = 77/168 (45.83%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETN----TTVFVSGIELTI--QLWTFYFKTFGRIDNINNFPERK-----YAFISFATHKEATKAICQRHGYII 732
            V+V N G  +++  +KE  ++ G ++++KV+  P   SKGF FVSF     A +A++ +N   +    +    A      +   +  ++        N      +++  ++  I  +     F  +G I +     + K     + F+ F++ +EATKA+ + +G I+
Sbjct:  196 VYVKNFGDDMDDEQMKEICAEAGKIVSLKVMTDPEGKSKGFGFVSFETPEEAEEAVNVLNGKEIGGRRLWAGRAK-KRAERAAEVKAEIEKKRQERINRFQGVNLYIKNLDDPIDDERLREEFSPYGTISSAKVMKDDKGNSKGFGFVCFSSPEEATKAVTEMNGRIL 362          
BLAST of Nucleolysin TIAR vs. Ensembl Nematostella
Match: EDO30178 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1I6])

HSP 1 Score: 48.9062 bits (115), Expect = 1.048e-7
Identity = 25/75 (33.33%), Postives = 41/75 (54.67%), Query Frame = 1
Query:  259 RVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFA 483
            +V+VGN+G   + + L EAF  +G + +V V R+P     GFAFV F +   A  A+D ++  R+    +K   +
Sbjct:    5 KVWVGNLGKEGDRHELWEAFKSYGELRDVWVARNP----PGFAFVEFYDARDARDAVDALDGERICGQRVKVELS 75          
BLAST of Nucleolysin TIAR vs. Ensembl Nematostella
Match: EDO42417 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1S3])

HSP 1 Score: 51.2174 bits (121), Expect = 1.577e-7
Identity = 31/95 (32.63%), Postives = 56/95 (58.95%), Query Frame = 1
Query:  214 PIRKIPSNINDRNI---VRVFVGNIGLRINEYMLKEAFSQFGPVLNV-KVIRHPNKI-SKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFA 483
            PIR   ++ +++N+     +F+GN+   ++E +L + FS FG +L   K++R  +   SKGFAF++F++   +  AI+ MN   L N  I  ++A
Sbjct:   83 PIRVNKASAHNKNLDVGANLFIGNLDTEVDEKLLYDTFSAFGVILQTPKIMRDSDTGNSKGFAFINFASFDASDAAIEAMNGQYLCNRPITVSYA 177          

HSP 2 Score: 50.8322 bits (120), Expect = 2.072e-7
Identity = 45/180 (25.00%), Postives = 82/180 (45.56%), Query Frame = 1
Query:  238 INDRNI-VRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHP-NKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFY--FKTFG---------RIDNINNFPERKYAFISFATHKEATKAICQRHG-YIIN 735
            I +RN    ++VG +  +++E ++ E F Q GPV+NV + +    ++ +G+ FV F     A  AI  MN  +++   I+ N A                +N++L+    +F+  ++  +     Y  F  FG         R  +  N   + +AFI+FA+   +  AI   +G Y+ N
Sbjct:    6 IAERNQDATIYVGGLDEKVSEALIWELFLQSGPVVNVHMPKDRITQLHQGYGFVEFLGEEDADYAIKVMNMIKVYGKPIRVNKA--------------SAHNKNLDVGANLFIGNLDTEVDEKLLYDTFSAFGVILQTPKIMRDSDTGN--SKGFAFINFASFDASDAAIEAMNGQYLCN 169          
BLAST of Nucleolysin TIAR vs. Ensembl Nematostella
Match: EDO49695 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG09])

HSP 1 Score: 51.2174 bits (121), Expect = 2.075e-7
Identity = 46/190 (24.21%), Postives = 81/190 (42.63%), Query Frame = 1
Query:  226 IPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNS 789
            IP   + +    +FVGN+   I+   L+ +F +FG VL+V + R        +AFV F++L +A KA              KC       G  HI +     Y  S +T T ++V G+   ++I      F  FG I  I+      +A+I + +   A+ A  +  G+ +    ++  +   ++   N 
Sbjct:  124 IPPEEDPKATRTLFVGNLETGISCQDLRLSFEKFGVVLDVDIKRPARGQGNTYAFVKFADLDVAAKA--------------KCAMQGQCIGRNHIKIG----YGRSQQT-TRLWVGGLGPWISIPELEREFDRFGAIRRIDYRKGGDHAYILYDSLDAASVAAREMRGFQMGDRRLRIDFADKEQARSND 294          
BLAST of Nucleolysin TIAR vs. Ensembl Medaka
Match: ENSORLT00000003147.2 (nucleolysin TIA-1 [Source:NCBI gene;Acc:101155125])

HSP 1 Score: 115.931 bits (289), Expect = 1.236e-29
Identity = 82/262 (31.30%), Postives = 128/262 (48.85%), Query Frame = 1
Query:   10 LNGQIFGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHI-------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            L GQI G C+ C +++   G + +    +Y + H T     +A++    +L ++V V +  TP ++           +  +   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A     PK          L++D V N+S  +N TV+  G+   LT Q+    F  FG+I  I  FPE+ Y+F+ F +H+ A  AI   +G  I G  +KCYWGK
Sbjct:   26 LFGQI-GPCKSCKMIVDTAGHDPYCFVEFYEHRHATA---TIAAMNGRKILGKEVKVNWATTPTSQKK---------DTSSHFHVFVGDLSPEITTDDIKAAFAPFGKISDCRVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPAPKTTNESSSSKQLSFDEVVNQSSPSNCTVYCGGVTTGLTEQIMRQTFSPFGQIMEIRVFPEKGYSFVRFNSHEAAAHAIVSVNGTSIEGYVVKCYWGK 274          

HSP 2 Score: 54.299 bits (129), Expect = 4.038e-8
Identity = 48/199 (24.12%), Postives = 82/199 (41.21%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            ++D     ++VGN+   + E ++ E F Q GP  + K+I         + FV F     AT  I  MN  ++    +K N+A   T  K           +   ++  VFV  +  E+T       F  FG+I       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K   + ++ +++ K
Sbjct:    1 MDDEQPKTLYVGNLSRDVTEALILELFGQIGPCKSCKMIVDTAGHDP-YCFVEFYEHRHATATIAAMNGRKILGKEVKVNWATTPTSQK-----------KDTSSHFHVFVGDLSPEITTDDIKAAFAPFGKISDCRVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPAPKTTNESSSSK 187          
BLAST of Nucleolysin TIAR vs. Ensembl Medaka
Match: ENSORLT00000019582.2 (nucleolysin TIA-1 [Source:NCBI gene;Acc:101158614])

HSP 1 Score: 109.768 bits (273), Expect = 2.237e-27
Identity = 79/270 (29.26%), Postives = 131/270 (48.52%), Query Frame = 1
Query:   19 QIF---GYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHI------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNS 789
            Q+F   G C+ C +++   G + +    +Y + H      +LA++    ++ ++V V +  TP ++           +  N   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK         L+++ V ++S  +N TV+  G+   LT QL    F  FG+I  +  FP++ Y+F+ F +H+ A  AI   +G  I+G  +KCYWGK      NS
Sbjct:   25 QVFTQIGPCKSCKMIVDTAGNDPYCFVEFYDHRHAAA---SLAAMNGRKIMGKEVKVNWATTPTSQKK---------DTSNHFHVFVGDLSPEITTEDVKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQHMGGQWLGGRQIRTNWATRKPPAPKTTYESNSKHLSFEEVMSQSSPSNCTVYCGGVSSGLTEQLMRQTFSAFGQIMEVRVFPDKGYSFVRFNSHESAAHAIVSVNGTSIDGHVVKCYWGKETPDMMNS 282          

HSP 2 Score: 52.373 bits (124), Expect = 1.998e-7
Identity = 46/197 (23.35%), Postives = 79/197 (40.10%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            + D     ++VGN+   + E ++ + F+Q GP  + K+I      +  + FV F +   A  ++  MN  ++    +K N+A   T  K    N+  V+   L           E+T +     F  FGRI       ++     + Y F+SF    +A  AI    G  + G  I+  W   K     +   +N K
Sbjct:    1 MEDDQPRTLYVGNLSRDVTEPLILQVFTQIGPCKSCKMIVD-TAGNDPYCFVEFYDHRHAAASLAAMNGRKIMGKEVKVNWATTPTSQKKDTSNHFHVFVGDLSP---------EITTEDVKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQHMGGQWLGGRQIRTNWATRKPPAPKTTYESNSK 187          
BLAST of Nucleolysin TIAR vs. Ensembl Medaka
Match: tial1 (TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:NCBI gene;Acc:101155294])

HSP 1 Score: 100.908 bits (250), Expect = 3.663e-24
Identity = 71/213 (33.33%), Postives = 106/213 (49.77%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP------LNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I+   ++ AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK +       L ++ V  +S   N TV+  GI  EL+  L    F  FG+I  I  FPE+ Y+FI F++H  A  AI   +G  I G A+KCYWGK
Sbjct:   72 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLNPDISTEDVRAAFTPFGKISDARVVKDLTTGKSKGYGFVSFYNKLDAENAIVHMAGQWLGGRQIRTNWATRKPPAPKSLQDSVSKQLRFEEVVTQSSPQNCTVYCGGIQSELSEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHDSAAHAIVSVNGTSIEGHAVKCYWGK 275          
BLAST of Nucleolysin TIAR vs. Ensembl Medaka
Match: tial1 (TIA1 cytotoxic granule associated RNA binding protein like 1 [Source:NCBI gene;Acc:101155294])

HSP 1 Score: 100.523 bits (249), Expect = 5.334e-24
Identity = 71/213 (33.33%), Postives = 106/213 (49.77%), Query Frame = 1
Query:  157 MLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL-GITGPKHIP------LNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            +L ++V V +  TP ++           +  N   VFVG++   I+   ++ AF+ FG + + +V++      SKG+ FVSF N   A  AI +M    L    I+ N+A      PK +       L ++ V  +S   N TV+  GI  EL+  L    F  FG+I  I  FPE+ Y+FI F++H  A  AI   +G  I G A+KCYWGK
Sbjct:   87 ILGKEVKVNWATTPSSQKK---------DTSNHFHVFVGDLNPDISTEDVRAAFTPFGKISDARVVKDLTTGKSKGYGFVSFYNKLDAENAIVHMAGQWLGGRQIRTNWATRKPPAPKSLQDSVSKQLRFEEVVTQSSPQNCTVYCGGIQSELSEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHDSAAHAIVSVNGTSIEGHAVKCYWGK 290          
BLAST of Nucleolysin TIAR vs. Ensembl Medaka
Match: ENSORLT00000003149.2 (nucleolysin TIA-1 [Source:NCBI gene;Acc:101155125])

HSP 1 Score: 89.3521 bits (220), Expect = 1.032e-20
Identity = 69/232 (29.74%), Postives = 111/232 (47.84%), Query Frame = 1
Query:   10 LNGQIFGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRH-PNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHI-------PLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFIS 675
            L GQI G C+ C +++   G + +    +Y + H T     +A++    +L ++V V +  TP ++           +  +   VFVG++   I    +K AF+ FG + + +V++      SKG+ FVSF N   A  AI  M    L    I+ N+A     PK          L++D V N+S  +N TV+  G+   LT Q+    F  FG+I  I  FPE+ Y+F+S
Sbjct:   26 LFGQI-GPCKSCKMIVDTAGHDPYCFVEFYEHRHATA---TIAAMNGRKILGKEVKVNWATTPTSQKK---------DTSSHFHVFVGDLSPEITTDDIKAAFAPFGKISDCRVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPAPKTTNESSSSKQLSFDEVVNQSSPSNCTVYCGGVTTGLTEQIMRQTFSPFGQIMEIRVFPEKGYSFVS 244          

HSP 2 Score: 53.9138 bits (128), Expect = 3.672e-8
Identity = 48/199 (24.12%), Postives = 82/199 (41.21%), Query Frame = 1
Query:  238 INDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRID------NINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGKGKKYTQNSDNNNNRK 810
            ++D     ++VGN+   + E ++ E F Q GP  + K+I         + FV F     AT  I  MN  ++    +K N+A   T  K           +   ++  VFV  +  E+T       F  FG+I       ++     + Y F+SF    +A  AI Q  G  + G  I+  W   K   + ++ +++ K
Sbjct:    1 MDDEQPKTLYVGNLSRDVTEALILELFGQIGPCKSCKMIVD-TAGHDPYCFVEFYEHRHATATIAAMNGRKILGKEVKVNWATTPTSQK-----------KDTSSHFHVFVGDLSPEITTDDIKAAFAPFGKISDCRVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPAPKTTNESSSSK 187          
BLAST of Nucleolysin TIAR vs. Planmine SMEST
Match: SMESG000055075.1 (SMESG000055075.1)

HSP 1 Score: 199.904 bits (507), Expect = 1.599e-62
Identity = 110/253 (43.48%), Postives = 157/253 (62.06%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYT-YPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGP---KHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            FG C  C+++  F    + Y    YT +P  +  + A+  IY   M + Q+ V +   P     P     + I+  N V++FVG+IGL ++E MLKE FSQFG +++ KV+R+P+  S+GFAFVSFSN   A +AI +M++T  HN  IKCN+A   G+ G    K+ P  Y+LVY E+  TNT V+V+G  LT +L   +F+ FGRID++  +PE+ +AFI+F TH+ A +AI QRHGY IN   IKC WGK
Sbjct:   30 FGQCISCHIIRDFSCQTNPYAFIEYTDHPSASLALSAMDGIY---MWNNQIKVNWSSGPSTIPGPAAVTSAKIDYSNSVQIFVGDIGLDVDEPMLKEGFSQFGQLIDAKVVRYPDGQSRGFAFVSFSNRDEAERAIQSMHKTWFHNRTIKCNWATRNGLDGEQFIKYTPRPYELVYKEAPLTNTNVYVAGENLTEELLNCHFQEFGRIDSVKVYPEKGHAFINFVTHEAAARAISQRHGYKINDNVIKCNWGK 279          

HSP 2 Score: 64.6994 bits (156), Expect = 8.257e-12
Identity = 48/182 (26.37%), Postives = 90/182 (49.45%), Query Frame = 1
Query:  247 RNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALG---ITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQ--LWTFYFKTFGRI--DNINNFPE---RKYAFISFATHKEATKAICQRHGYIINGTAIKCYWG 762
            +N   ++VGN+   +N+ +L   F  FG  ++  +IR  +  +  +AF+ +++   A+ A+  M+   + N  IK N++ G   I GP  +  +  + Y+ S++    +FV  I L +   +    F  FG++    +  +P+   R +AF+SF+   EA +AI   H    +   IKC W 
Sbjct:    4 KNNRTIYVGNLPDAVNDQLLIRIFGNFGQCISCHIIRDFSCQTNPYAFIEYTDHPSASLALSAMDGIYMWNNQIKVNWSSGPSTIPGPAAV-TSAKIDYSNSVQ----IFVGDIGLDVDEPMLKEGFSQFGQLIDAKVVRYPDGQSRGFAFVSFSNRDEAERAIQSMHKTWFHNRTIKCNWA 180          
BLAST of Nucleolysin TIAR vs. Planmine SMEST
Match: SMESG000055074.1 (SMESG000055074.1)

HSP 1 Score: 199.519 bits (506), Expect = 2.500e-62
Identity = 110/253 (43.48%), Postives = 157/253 (62.06%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYT-YPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGP---KHIPLNYDLVYNESLETNTTVFVSGIELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            FG C  C+++  F    + Y    YT +P  +  + A+  IY   M + Q+ V +   P     P     + I+  N V++FVG+IGL ++E MLKE FSQFG +++ KV+R+P+  S+GFAFVSFSN   A +AI +M++T  HN  IKCN+A   G+ G    K+ P  Y+LVY E+  TNT V+V+G  LT +L   +F+ FGRID++  +PE+ +AFI+F TH+ A +AI QRHGY IN   IKC WGK
Sbjct:   30 FGQCISCHIIRDFSCQTNPYAFIEYTDHPSASLALSAMDGIY---MWNNQIKVNWSSGPSTIPGPAAVTSAKIDYSNSVQIFVGDIGLDVDEPMLKEGFSQFGQLIDAKVVRYPDGQSRGFAFVSFSNRDEAERAIQSMHKTWFHNRTIKCNWATRNGLDGEQFIKYTPRPYELVYKEAPLTNTNVYVAGENLTEELLNCHFQEFGRIDSVKVYPEKGHAFINFVTHEAAARAISQRHGYKINDNVIKCNWGK 279          

HSP 2 Score: 64.6994 bits (156), Expect = 8.449e-12
Identity = 48/182 (26.37%), Postives = 90/182 (49.45%), Query Frame = 1
Query:  247 RNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALG---ITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQ--LWTFYFKTFGRI--DNINNFPE---RKYAFISFATHKEATKAICQRHGYIINGTAIKCYWG 762
            +N   ++VGN+   +N+ +L   F  FG  ++  +IR  +  +  +AF+ +++   A+ A+  M+   + N  IK N++ G   I GP  +  +  + Y+ S++    +FV  I L +   +    F  FG++    +  +P+   R +AF+SF+   EA +AI   H    +   IKC W 
Sbjct:    4 KNNRTIYVGNLPDAVNDQLLIRIFGNFGQCISCHIIRDFSCQTNPYAFIEYTDHPSASLALSAMDGIYMWNNQIKVNWSSGPSTIPGPAAV-TSAKIDYSNSVQ----IFVGDIGLDVDEPMLKEGFSQFGQLIDAKVVRYPDGQSRGFAFVSFSNRDEAERAIQSMHKTWFHNRTIKCNWA 180          
BLAST of Nucleolysin TIAR vs. Planmine SMEST
Match: SMESG000055085.1 (SMESG000055085.1)

HSP 1 Score: 186.808 bits (473), Expect = 4.100e-57
Identity = 104/257 (40.47%), Postives = 161/257 (62.65%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIF---DRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGP---KHIPLNYDLVYNESLETNTTVFVSGI--ELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            FG C  C+++  F G  + Y   +  +  +     A+A + N+++   Q+ V +    + P +  T ++     ++    +++FVG+IGL +NE MLK+AFSQFG +++VKV+R+P+  SKGFAF+SF+N   A  AI +M++T LHN  IKCN+A   G       ++ P  Y+LVY E+  TNT V+V+GI   LT +L   +F+ FGRID++  FP++ YAFI+++TH+ A +AI QRHGY IN   +KC WGK
Sbjct:   30 FGQCVGCHIMRDFSGQINPYA--FIEFNEHQAASLAVAGMNNISLWGHQLKVNWASGSQNPASNITNVK-----VDYSKAIQIFVGDIGLDVNEQMLKDAFSQFGSIIDVKVVRYPDGQSKGFAFLSFTNRQDAENAITSMHKTWLHNRTIKCNWATRNGTDEEQFKQYTPRPYELVYKEAPLTNTNVYVAGITENLTEELVRCHFEEFGRIDSVKVFPDKAYAFINYSTHEAAARAISQRHGYKINNNVVKCNWGK 279          

HSP 2 Score: 68.1662 bits (165), Expect = 5.727e-13
Identity = 45/174 (25.86%), Postives = 83/174 (47.70%), Query Frame = 1
Query:  262 VFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVS--GIELTIQLWTFYFKTFGRIDNIN--NFPE---RKYAFISFATHKEATKAICQRHGYIINGTAIKCYWG 762
            ++VGN+   I + +L   F  FG  +   ++R  +     +AF+ F+    A+ A+  MN   L    +K N+A G   P     N  + Y+++++    +FV   G+++  Q+    F  FG I ++    +P+   + +AF+SF   ++A  AI   H   ++   IKC W 
Sbjct:    9 IYVGNLPHEITDQLLLTVFGHFGQCVGCHIMRDFSGQINPYAFIEFNEHQAASLAVAGMNNISLWGHQLKVNWASGSQNPASNITNVKVDYSKAIQ----IFVGDIGLDVNEQMLKDAFSQFGSIIDVKVVRYPDGQSKGFAFLSFTNRQDAENAITSMHKTWLHNRTIKCNWA 178          
BLAST of Nucleolysin TIAR vs. Planmine SMEST
Match: SMESG000044648.1 (SMESG000044648.1)

HSP 1 Score: 181.415 bits (459), Expect = 2.217e-55
Identity = 103/254 (40.55%), Postives = 157/254 (61.81%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFAL--GITGP---KHIPLNYDLVYNESLETNTTVFVSGIE--LTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            FG C  C+++  F G  + Y   +  Y +++    ALA++  + M + Q+ V +       +       S I+  N +++FVG+IGL ++E MLKE FS+FG V++ KV+R+ +  S+GFAFV++S    A KAI+NM++T  HN  IKCN+A   G+ G    K+ P  Y+LVY E+  TNT V+++GI   +T +L   +F+ FGRID +  + E+ +AFI+F TH+ A +AI QRHGY IN + IKC WGK
Sbjct:   30 FGQCASCHIIRDFSGQTNPY--AFIEYTNHSAASLALAAMDGIYMWNNQIKVNWSSGNSLGTAAPAITASKIDYSNTIQIFVGDIGLDVDESMLKEGFSKFGSVIDAKVVRYQDGQSRGFAFVAYSRREDAEKAIENMHKTWFHNRTIKCNWATRNGLDGDQFIKYTPRPYELVYKEAPLTNTNVYIAGIPEGITEELIRVHFEEFGRIDAVKIYQEKAHAFINFVTHEAAARAISQRHGYKINESVIKCNWGK 281          

HSP 2 Score: 53.9138 bits (128), Expect = 3.105e-8
Identity = 47/183 (25.68%), Postives = 85/183 (46.45%), Query Frame = 1
Query:  247 RNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNF----ALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQ--LWTFYFKTFG-----RIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWG 762
            RN   ++VGN+   I +++L   F  FG   +  +IR  +  +  +AF+ ++N S A+ A+  M+   + N  IK N+    +LG   P       D  Y+ +++    +FV  I L +   +    F  FG     ++    +   R +AF++++  ++A KAI   H    +   IKC W 
Sbjct:    4 RNNRTIYVGNLPDAITDHLLLRIFGNFGQCASCHIIRDFSGQTNPYAFIEYTNHSAASLALAAMDGIYMWNNQIKVNWSSGNSLGTAAPAITASKID--YSNTIQ----IFVGDIGLDVDESMLKEGFSKFGSVIDAKVVRYQDGQSRGFAFVAYSRREDAEKAIENMHKTWFHNRTIKCNWA 180          
BLAST of Nucleolysin TIAR vs. Planmine SMEST
Match: SMESG000044649.1 (SMESG000044649.1)

HSP 1 Score: 145.591 bits (366), Expect = 1.385e-40
Identity = 91/259 (35.14%), Postives = 132/259 (50.97%), Query Frame = 1
Query:   25 FGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYNVNMLDRQVSVIFDR-TPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEYMLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTRLHNCIIKCNFALGITGPKHIPLNYDLVYNESL-----------ETNTTVFVSGIELTIQLWTFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIKCYWGK 765
            FG C  C +       N    S Y  + +     +ALA + +  M   Q++V+      +  S P       ++    V++FVG IG  I+E  LK+ FS  G V++ KV+R P+   KGFAFVSFSN   A+ AI +MN T  HN  I+CN+A        +P N  + + +S            ETNT+V+V    L+  +    F+ FG+I NI  FPE+ +AF+++ TH  A  AI Q +GY IN   +KC WGK
Sbjct:   30 FGVCISCQL-------NLETSSAYIEFDNELSAEKALA-MNDTPMDSNQMNVVIAYVEEVQNSAPYFVASKKVDYSTPVQIFVGGIGFDIDEAKLKDGFSHCGQVIDAKVVRGPDGQHKGFAFVSFSNEDEASAAIQSMNNTMFHNRKIQCNWATKSKNGNGVPPNKKMAFGQSTKTLEEISYEAPETNTSVYVMAENLSEDILRPTFERFGKIKNIKAFPEKNHAFVNYDTHDAAAYAIQQLNGYKINSIELKCNWGK 280          
The following BLAST results are available for this feature:
BLAST of Nucleolysin TIAR vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TIA18.135e-2731.01TIA1 cytotoxic granule associated RNA binding prot... [more]
TIA18.845e-2731.01TIA1 cytotoxic granule associated RNA binding prot... [more]
TIA15.224e-2630.86TIA1 cytotoxic granule associated RNA binding prot... [more]
TIAL11.657e-2534.27TIA1 cytotoxic granule associated RNA binding prot... [more]
TIAL11.763e-2534.27TIA1 cytotoxic granule associated RNA binding prot... [more]
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BLAST of Nucleolysin TIAR vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tiar-12.748e-3132.79TIA-1/TIAL RNA binding protein homolog [Source:Un... [more]
tiar-14.961e-2933.03TIA-1/TIAL RNA binding protein homolog [Source:Un... [more]
tiar-16.687e-2933.81TIA-1/TIAL RNA binding protein homolog [Source:Un... [more]
tiar-14.904e-2836.57TIA-1/TIAL RNA binding protein homolog [Source:Un... [more]
tiar-28.311e-2228.63TIA-1/TIAL RNA binding protein homolog [Source:Un... [more]
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BLAST of Nucleolysin TIAR vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trv1.236e-2736.13gene:FBgn0085391 transcript:FBtr0334897[more]
trv1.255e-2736.13gene:FBgn0085391 transcript:FBtr0344218[more]
trv1.293e-2736.13gene:FBgn0085391 transcript:FBtr0112583[more]
trv1.679e-2736.13gene:FBgn0085391 transcript:FBtr0334896[more]
trv2.581e-2736.13gene:FBgn0085391 transcript:FBtr0344217[more]
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BLAST of Nucleolysin TIAR vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tia11.278e-2629.55TIA1 cytotoxic granule-associated RNA binding prot... [more]
tia11.372e-2629.55TIA1 cytotoxic granule-associated RNA binding prot... [more]
tia1l1.674e-2630.80cytotoxic granule-associated RNA binding protein 1... [more]
tia1l5.425e-2630.42cytotoxic granule-associated RNA binding protein 1... [more]
tial11.031e-2533.80TIA1 cytotoxic granule-associated RNA binding prot... [more]
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BLAST of Nucleolysin TIAR vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tia12.553e-2829.34TIA1 cytotoxic granule-associated RNA binding prot... [more]
tia13.449e-2829.34TIA1 cytotoxic granule-associated RNA binding prot... [more]
tia12.413e-2729.57TIA1 cytotoxic granule-associated RNA binding prot... [more]
tia12.581e-2729.57TIA1 cytotoxic granule-associated RNA binding prot... [more]
tia13.194e-2729.57TIA1 cytotoxic granule-associated RNA binding prot... [more]
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BLAST of Nucleolysin TIAR vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tia11.493e-2630.62cytotoxic granule-associated RNA binding protein 1... [more]
Tia11.606e-2630.62cytotoxic granule-associated RNA binding protein 1... [more]
Tial15.866e-2634.27Tia1 cytotoxic granule-associated RNA binding prot... [more]
Tial11.173e-2534.27Tia1 cytotoxic granule-associated RNA binding prot... [more]
Tial11.173e-2534.27Tia1 cytotoxic granule-associated RNA binding prot... [more]
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BLAST of Nucleolysin TIAR vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P31483|TIA1_HUMAN4.248e-2631.01Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9... [more]
sp|P52912|TIA1_MOUSE1.123e-2530.62Nucleolysin TIA-1 OS=Mus musculus OX=10090 GN=Tia1... [more]
sp|Q01085|TIAR_HUMAN7.959e-2534.27Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 ... [more]
sp|P70318|TIAR_MOUSE8.728e-2534.27Nucleolysin TIAR OS=Mus musculus OX=10090 GN=Tial1... [more]
sp|Q13310|PABP4_HUMAN2.003e-1527.84Polyadenylate-binding protein 4 OS=Homo sapiens OX... [more]
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BLAST of Nucleolysin TIAR vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
D5JG774.620e-6042.86TIA1-like protein OS=Dugesia japonica OX=6161 GN=T... [more]
D5JG781.405e-5241.80TIA1-like protein (Fragment) OS=Dugesia japonica O... [more]
D5JG756.006e-3742.71TIA1-like protein (Fragment) OS=Dugesia japonica O... [more]
A0A2H8TUQ65.557e-3135.81Nucleolysin TIAR OS=Melanaphis sacchari OX=742174 ... [more]
A0A2S2PKR15.557e-3135.81Nucleolysin TIAR OS=Schizaphis graminum OX=13262 G... [more]
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BLAST of Nucleolysin TIAR vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tia1l5.042e-2730.57TIA1 cytotoxic granule associated RNA binding prot... [more]
tia1l5.042e-2730.57TIA1 cytotoxic granule associated RNA binding prot... [more]
tial13.856e-2231.36TIA1 cytotoxic granule associated RNA binding prot... [more]
tia1l1.499e-1627.90TIA1 cytotoxic granule associated RNA binding prot... [more]
ENSAMXT00000035946.12.990e-1224.60polyadenylate-binding protein 1-like [Source:NCBI ... [more]
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BLAST of Nucleolysin TIAR vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tia1l7.055e-2838.33cytotoxic granule-associated RNA binding protein 1... [more]
pabpc41.286e-1328.65poly(A) binding protein, cytoplasmic 4 (inducible ... [more]
pabpc44.929e-1025.00poly(A) binding protein, cytoplasmic 4 (inducible ... [more]
ENSPMAT00000004893.16.381e-1026.04pep scaffold:Pmarinus_7.0:GL479484:4:2056:-1 gene:... [more]
sf3b41.658e-928.33splicing factor 3b, subunit 4 [Source:ZFIN;Acc:ZDB... [more]
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BLAST of Nucleolysin TIAR vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
PUB16.950e-1124.12Poly (A)+ RNA-binding protein; abundant mRNP-compo... [more]
PAB18.959e-1026.97Poly(A) binding protein; part of the 3'-end RNA-pr... [more]
HSH497.188e-838.64U2-snRNP associated splicing factor; similar to th... [more]
NSR12.456e-730.67Nucleolar protein that binds nuclear localization ... [more]
RNA151.070e-632.00Component of the cleavage and polyadenylation fact... [more]
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BLAST of Nucleolysin TIAR vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO324922.723e-1530.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO332063.473e-827.43Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO301781.048e-733.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO424171.577e-732.63Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO496952.075e-724.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Nucleolysin TIAR vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000003147.21.236e-2931.30nucleolysin TIA-1 [Source:NCBI gene;Acc:101155125][more]
ENSORLT00000019582.22.237e-2729.26nucleolysin TIA-1 [Source:NCBI gene;Acc:101158614][more]
tial13.663e-2433.33TIA1 cytotoxic granule associated RNA binding prot... [more]
tial15.334e-2433.33TIA1 cytotoxic granule associated RNA binding prot... [more]
ENSORLT00000003149.21.032e-2029.74nucleolysin TIA-1 [Source:NCBI gene;Acc:101155125][more]
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BLAST of Nucleolysin TIAR vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000055075.11.599e-6243.48SMESG000055075.1[more]
SMESG000055074.12.500e-6243.48SMESG000055074.1[more]
SMESG000055085.14.100e-5740.47SMESG000055085.1[more]
SMESG000044648.12.217e-5540.55SMESG000044648.1[more]
SMESG000044649.11.385e-4035.14SMESG000044649.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027620 ID=SMED30027620|Name=Nucleolysin TIAR|organism=Schmidtea mediterranea sexual|type=transcript|length=816bp
ATGAACTATTTAAATGGACAAATATTCGGATATTGCGAGCATTGCAATGT
CCTTATCATCTTTGATGGTGTGAATTCATGGTATGAAAGTCCATACTACA
CGTATCCGCATAATACGGGACCTGTTCAAGCTCTAGCGTCTATATATAAT
GTTAATATGTTGGATCGTCAAGTCAGTGTCATCTTCGATAGAACTCCAAT
TGCTGAATCAACCCCAATACGAAAAATACCAAGCAATATTAATGATAGAA
ACATAGTAAGGGTATTTGTAGGCAATATTGGTCTTCGTATAAACGAATAT
ATGCTCAAAGAAGCTTTCAGTCAATTTGGTCCGGTGCTGAATGTTAAAGT
CATTCGACACCCGAACAAAATATCAAAAGGATTTGCTTTTGTTTCCTTTT
CAAATTTGAGCATAGCAACAAAAGCCATTGATAATATGAATCAAACAAGG
CTGCATAATTGTATAATCAAATGCAATTTTGCATTAGGAATAACGGGTCC
TAAACATATCCCTCTCAACTACGACTTGGTTTACAACGAATCTTTAGAAA
CAAATACTACCGTTTTCGTATCCGGAATCGAATTGACGATTCAACTGTGG
ACTTTTTACTTTAAAACATTTGGTAGAATTGACAATATTAACAATTTCCC
TGAAAGAAAGTATGCATTTATTAGTTTTGCGACTCACAAAGAGGCCACCA
AGGCCATTTGTCAACGCCATGGGTATATCATAAATGGAACTGCAATTAAA
TGTTATTGGGGCAAGGGAAAGAAATATACGCAAAACTCTGATAATAATAA
TAATAGGAAGGGATAA
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protein sequence of SMED30027620-orf-1

>SMED30027620-orf-1 ID=SMED30027620-orf-1|Name=SMED30027620-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=272bp
MNYLNGQIFGYCEHCNVLIIFDGVNSWYESPYYTYPHNTGPVQALASIYN
VNMLDRQVSVIFDRTPIAESTPIRKIPSNINDRNIVRVFVGNIGLRINEY
MLKEAFSQFGPVLNVKVIRHPNKISKGFAFVSFSNLSIATKAIDNMNQTR
LHNCIIKCNFALGITGPKHIPLNYDLVYNESLETNTTVFVSGIELTIQLW
TFYFKTFGRIDNINNFPERKYAFISFATHKEATKAICQRHGYIINGTAIK
CYWGKGKKYTQNSDNNNNRKG*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0003676nucleic acid binding
GO:0000166nucleotide binding
Vocabulary: INTERPRO
TermDefinition
IPR035979RBD_domain_sf
IPR000504RRM_dom
IPR012677Nucleotide-bd_a/b_plait_sf
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000504RNA recognition motif domainSMARTSM00360rrm1_1coord: 187..252
e-value: 0.0071
score: 25.6
coord: 87..159
e-value: 1.6E-22
score: 90.8
IPR000504RNA recognition motif domainPFAMPF00076RRM_1coord: 203..250
e-value: 7.2E-7
score: 28.9
coord: 88..156
e-value: 4.3E-18
score: 64.9
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 86..163
score: 16.449
IPR000504RNA recognition motif domainPROSITEPS50102RRMcoord: 186..256
score: 10.855
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 169..262
e-value: 1.9E-13
score: 52.4
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 56..164
e-value: 4.7E-22
score: 80.6
NoneNo IPR availablePANTHERPTHR47640FAMILY NOT NAMEDcoord: 176..260
NoneNo IPR availablePANTHERPTHR47640:SF5TIA-1/TIAL RNA BINDING PROTEIN HOMOLOGcoord: 176..260
NoneNo IPR availablePANTHERPTHR47640FAMILY NOT NAMEDcoord: 84..161
NoneNo IPR availablePANTHERPTHR47640:SF5TIA-1/TIAL RNA BINDING PROTEIN HOMOLOGcoord: 84..161
NoneNo IPR availableCDDcd00590RRM_SFcoord: 88..159
e-value: 6.12243E-21
score: 81.9677
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 85..257