Superkiller viralicidic activity 2-like 2

Overview


Name	Superkiller viralicidic activity 2-like 2
Smed ID	SMED30027607
Length (bp)	3197

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Superkiller viralicidic activity 2-like 2 (SMED30027607) t-SNE clustered cells

Violin plots show distribution of expression levels for Superkiller viralicidic activity 2-like 2 (SMED30027607) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Superkiller viralicidic activity 2-like 2 (SMED30027607) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Superkiller viralicidic activity 2-like 2 (SMED30027607) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30027607

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30027607	SMESG000004886.1 SMESG000004673.1	SmedASXL_012235	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30027607	SMESG000004886.1 SMESG000004673.1	SmedASXL_012235	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

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Homology

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Human
Match: MTREX (Mtr4 exosome RNA helicase [Source:HGNC Symbol;Acc:HGNC:18734])

HSP 1 Score: 1058.9 bits (2737), Expect = 0.000e+0
Identity = 535/968 (55.27%), Postives = 696/968 (71.90%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSD-STSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAP-RPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            R+K+  V   E  +HEVA+P   ++ PLK  V    K YPF LD FQ+ AI+C+DN QSVLVSAHTSAGKTV AEYAIA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHV++T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L    D +  ++ G        K  SNVFKIV++IME   +P+I+FSFSKK+CE YA Q+ KL+FN+DEE   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGL+K LFATETFAMG+NMPARTVLFT+ARK+DG ++RWIS+ EYIQMSGRAGRRG D+RG VILMVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   +P   E +K     Y ++ +  EE    Y+K+ + L     +  +YIHK    + F+QPGRL+KVK + +DFGWG VVN  ++    +K +S   D  LY+VE LL  +     N  T    P +P E    +V  + +  +SAIS+VRL +P+DLRP  NR+ V+++I++++++F                  + +P+LD I D+ I D+   K+ +K+E++E ++ +H   N  N E +     +K +  ++I++ ++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADELL+TE++  G+FN+L+  Q  A +SC VF+E SSEMP L   L+   R +Q  AK +A +S E +L+++ E+Y+ SFKPH+MDVV  WA G TF  +   T +FEGSIIRC+R LEE+LRQ+  AAK IGNT LE KF E I  IKRDIVFAASLYL
Sbjct:   98 RVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGR---KGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSN--VKPNSGELD-PLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFP-----------------DGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 1042

[Close]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Human
Match: SKIV2L (Ski2 like RNA helicase [Source:HGNC Symbol;Acc:HGNC:10898])

HSP 1 Score: 543.502 bits (1399), Expect = 1.634e-173
Identity = 341/966 (35.30%), Postives = 517/966 (53.52%), Query Frame = 3

Query:  390 IVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAM----NKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESL----KALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGE---------AKVAEVTLLKLKT--ISAISAVRLVMPQDLRPTGNREKVI-------QXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFE-EILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            I  P   + FE D FQK AI  ++   SV V+AHTSAGKTV+AEYAIA A     R IYT+PIKALSNQK+R+F   F +VGLLTGDV L P AS LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LPD +    LSAT+PNA +FA+WI  L  +  +V+ T  RPVPL+HY+F  N       L L++D +G F    + +A+     ++  ++ +   +  +     +Q     +  +  L    +L P++VF+FS+  C+  A+ L  L+  +  E + +    +  +  L  +D++LPQVL    LL RG+GVHH G+LPILKE VE+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DGS +R +   EY+QM+GRAGRRG D  GTVIL+    + ++ D  +++ G P  L S F +TY M+LNL+RV+ +  E M++RSF +F ++      E++L    K L A  E     Q      Y+   E L          I +S   +  +  GR++ VK        G ++ +          S++T+     LV C   ++  P D        P P +             + T++KL+   ++AI+   L +        N EK++       Q   K       + + +    +         P LD + D+++ D S ++   +    E+ +   + ++   F  + LK    +  +  +     + ++  +S++ + E   R  VLR L Y ++   ++L GRVAC ++ + ELL+TEL+     + L P + AA +S LV +        L   L      ++  AK + ++ V C L+   E ++      +++VV  WA G  F +L   +   EG ++RCI+ L E+ R L  AA+ +G   L  K   A  L++RDIVFAASLY
Sbjct:  300 IPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQL-PVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKRLGALEEPDMTGQLVDLPEYYSWGEELTETQHMIQRRIMESVNGLKSLSAGRVVVVKNQEHHNALGVILQVS---------SNSTSRVFTTLVLCDKPLSQDPQDRGPATAEVPYPDDLVGFKLFLPEGPCDHTVVKLQPGDMAAITTKVLRV--------NGEKILEDFSKRQQPKFKKDPPLAAVTTAVQELLRLAQAHPAGPPTLDPVNDLQLKDMSVVEGGLRARKLEELIQGAQCVHSPRFPAQYLK--LRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMS-SHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDAGDQLPNTLKQGIERVRAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLY 1244

[Close]

Query:  390 IVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAM----NKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESL----KALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGE---------AKVAEVTLLKLKT--ISAISAVRLVMPQDLRPTGNREKVI-------QXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFE-EILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            I  P   + FE D FQK AI  ++   SV V+AHTSAGKTV+AEYAIA A     R IYT+PIKALSNQK+R+F   F +VGLLTGDV L P AS LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LPD +    LSAT+PNA +FA+WI  L  +  +V+ T  RPVPL+HY+F  N       L L++D +G F    + +A+     ++  ++ +   +  +     +Q     +  +  L    +L P++VF+FS+  C+  A+ L  L+  +  E + +    +  +  L  +D++LPQVL    LL RG+GVHH G+LPILKE VE+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DGS +R +   EY+QM+GRAGRRG D  GTVIL+    + ++ D  +++ G P  L S F +TY M+LNL+RV+ +  E M++RSF +F ++      E++L    K L A  E     Q      Y+   E L          I +S   +  +  GR++ VK        G ++ +          S++T+     LV C   ++  P D        P P +             + T++KL+   ++AI+   L +        N EK++       Q   K       + + +    +         P LD + D+++ D S ++   +    E+ +   + ++   F  + LK    +  +  +     + ++  +S++ + E   R  VLR L Y ++   ++L GRVAC ++ + ELL+TEL+     + L P + AA +S LV +        L   L      ++  AK + ++ V C L+   E ++      +++VV  WA G  F +L   +   EG ++RCI+ L E+ R L  AA+ +G   L  K   A  L++RDIVFAASLY
Sbjct:  300 IPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQL-PVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKRLGALEEPDMTGQLVDLPEYYSWGEELTETQHMIQRRIMESVNGLKSLSAGRVVVVKNQEHHNALGVILQVS---------SNSTSRVFTTLVLCDKPLSQDPQDRGPATAEVPYPDDLVGFKLFLPEGPCDHTVVKLQPGDMAAITTKVLRV--------NGEKILEDFSKRQQPKFKKDPPLAAVTTAVQELLRLAQAHPAGPPTLDPVNDLQLKDMSVVEGGLRARKLEELIQGAQCVHSPRFPAQYLK--LRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMS-SHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDAGDQLPNTLKQGIERVRAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLY 1244

[Close]

Query:  390 IVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAM----NKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESL----KALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGE---------AKVAEVTLLKLKT--ISAISAVRLVMPQDLRPTGNREKVI-------QXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFE-EILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            I  P   + FE D FQK AI  ++   SV V+AHTSAGKTV+AEYAIA A     R IYT+PIKALSNQK+R+F   F +VGLLTGDV L P AS LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LPD +    LSAT+PNA +FA+WI  L  +  +V+ T  RPVPL+HY+F  N       L L++D +G F    + +A+     ++  ++ +   +  +     +Q     +  +  L    +L P++VF+FS+  C+  A+ L  L+  +  E + +    +  +  L  +D++LPQVL    LL RG+GVHH G+LPILKE VE+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DGS +R +   EY+QM+GRAGRRG D  GTVIL+    + ++ D  +++ G P  L S F +TY M+LNL+RV+ +  E M++RSF +F ++      E++L    K L A  E     Q      Y+   E L          I +S   +  +  GR++ VK        G ++ +          S++T+     LV C   ++  P D        P P +             + T++KL+   ++AI+   L +        N EK++       Q   K       + + +    +         P LD + D+++ D S ++   +    E+ +   + ++   F  + LK    +  +  +     + ++  +S++ + E   R  VLR L Y ++   ++L GRVAC ++ + ELL+TEL+     + L P + AA +S LV +        L   L      ++  AK + ++ V C L+   E ++      +++VV  WA G  F +L   +   EG ++RCI+ L E+ R L  AA+ +G   L  K   A  L++RDIVFAASLY
Sbjct:  300 IPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQL-PVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKRLGALEEPDMTGQLVDLPEYYSWGEELTETQHMIQRRIMESVNGLKSLSAGRVVVVKNQEHHNALGVILQVS---------SNSTSRVFTTLVLCDKPLSQDPQDRGPATAEVPYPDDLVGFKLFLPEGPCDHTVVKLQPGDMAAITTKVLRV--------NGEKILEDFSKRQQPKFKKDPPLAAVTTAVQELLRLAQAHPAGPPTLDPVNDLQLKDMSVVEGGLRARKLEELIQGAQCVHSPRFPAQYLK--LRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMS-SHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDAGDQLPNTLKQGIERVRAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLY 1244

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Query:  390 IVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAM----NKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESL----KALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGE---------AKVAEVTLLKLKT--ISAISAVRLVMPQDLRPTGNREKVI-------QXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFE-EILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            I  P   + FE D FQK AI  ++   SV V+AHTSAGKTV+AEYAIA A     R IYT+PIKALSNQK+R+F   F +VGLLTGDV L P AS LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LPD +    LSAT+PNA +FA+WI  L  +  +V+ T  RPVPL+HY+F  N       L L++D +G F    + +A+     ++  ++ +   +  +     +Q     +  +  L    +L P++VF+FS+  C+  A+ L  L+  +  E + +    +  +  L  +D++LPQVL    LL RG+GVHH G+LPILKE VE+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DGS +R +   EY+QM+GRAGRRG D  GTVIL+    + ++ D  +++ G P  L S F +TY M+LNL+RV+ +  E M++RSF +F ++      E++L    K L A  E     Q      Y+   E L          I +S   +  +  GR++ VK        G ++ +          S++T+     LV C   ++  P D        P P +             + T++KL+   ++AI+   L +        N EK++       Q   K       + + +    +         P LD + D+++ D S ++   +    E+ +   + ++   F  + LK    +  +  +     + ++  +S++ + E   R  VLR L Y ++   ++L GRVAC ++ + ELL+TEL+     + L P + AA +S LV +        L   L      ++  AK + ++ V C L+   E ++      +++VV  WA G  F +L   +   EG ++RCI+ L E+ R L  AA+ +G   L  K   A  L++RDIVFAASLY
Sbjct:  300 IPQPAFQWAFEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDVERGVVWEEVLIMLPDHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQL-PVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLNRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALAELTKRLGALEEPDMTGQLVDLPEYYSWGEELTETQHMIQRRIMESVNGLKSLSAGRVVVVKNQEHHNALGVILQVS---------SNSTSRVFTTLVLCDKPLSQDPQDRGPATAEVPYPDDLVGFKLFLPEGPCDHTVVKLQPGDMAAITTKVLRV--------NGEKILEDFSKRQQPKFKKDPPLAAVTTAVQELLRLAQAHPAGPPTLDPVNDLQLKDMSVVEGGLRARKLEELIQGAQCVHSPRFPAQYLK--LRERMQIQKEMERLRFLLSDQSLLLLPEYHQRVEVLRTLGYVDEAGTVKLAGRVACAMS-SHELLLTELMFDNALSTLRPEEIAALLSGLVCQSPGDAGDQLPNTLKQGIERVRAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLY 1244

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Celegans
Match: mtr-4 (mRNA transport homolog 4 [Source:UniProtKB/Swiss-Prot;Acc:Q23223])

HSP 1 Score: 899.042 bits (2322), Expect = 0.000e+0
Identity = 471/973 (48.41%), Postives = 640/973 (65.78%), Query Frame = 3

Query:  303 IKIHKVSGD-ESFSHEVAVPPTIEFEPLKE--IVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARS---QKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTP-TRAPRPGEAKVAEVTL-LKLKTISAISAVRLVMPQDL-RPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            I +H +  D E+ +HEVA+PP  EF  L+E     P K YPF+LD FQK AI CIDN QSVLVSAHTSAGKTV+A YAIAK L +KQRVIYT+PIKALSNQKYRE  EEF +VGL+TGDVTL+P+AS L+MTTEIL+SMLYRGS IM+EVGWV++DEIHYMRD+ERGVVWEE+I+L+   I+ AFLSATIPNARQFA+W++ +  Q  +VV+T+YRP PLQH+++P  G+G+  VV+ KG F ED F+ AM+ L    DS    AGS    R+    + +SNV KI+R +  +     IVFSFS+KECE YA  L  ++FN D E   V  V+++A+  LS  D++LPQ+L  LPLLRRGIGVHH GL+PILKET+EILF EGL+K LFATETF+MGLNMPARTV+FTSARK+DGS+ R+I++ EYIQM+GRAGRRGKD+RGTVILMVD  MS  DA++II+G  DPLNS F +TYNM+LNLMRVEG+   ++I  SF QFQ+ A +PE ++    +           E    +   L + L+    + +    +   ++ F+  GRL KVK    DF WG +   K++Q      +    ++ +YL + ++ +      +   P T  P     K   + + + +  I+AISAVRL +P D+ +P G                            +       +P+LD I+D++I      ++  + +S E +L  H      N +++ K F +K+    E+  L+ E    +S + + EL +RKRVLRRL Y  + D + LKG VACE++ +DEL++TE+LLKG+FN L+ +QTAA +SC VF++K +  P L   L T    L  +A+ +A +S EC+++V  + Y+ SF P +MDVV +W +G TF ++V  T +FEGSIIR +R LEEVLR++ NAAK + N  LE+KF +A + +KRDIVFAASLYL
Sbjct:   83 IIVHTIRTDNENCTHEVAIPPNAEFAELRENSGTEPAKYYPFQLDAFQKQAILCIDNNQSVLVSAHTSAGKTVVATYAIAKCLREKQRVIYTSPIKALSNQKYRELEEEFKDVGLMTGDVTLNPDASCLVMTTEILRSMLYRGSEIMKEVGWVVYDEIHYMRDKERGVVWEETIILMSKNIKQAFLSATIPNARQFAQWVASIKQQPVNVVYTDYRPTPLQHWIYPVGGEGMYEVVNVKGEFREDKFRDAMSGLATAGDS----AGSFNKRRTGGGTQGDSNVLKIIRSVASNDGLNCIVFSFSRKECESYAISLKDMDFNKDHEKGMVKSVYESAIAQLSPEDQKLPQILNILPLLRRGIGVHHSGLMPILKETIEILFGEGLVKVLFATETFSMGLNMPARTVVFTSARKFDGSDNRYITSGEYIQMAGRAGRRGKDDRGTVILMVDSAMSADDAKQIIKGATDPLNSQFRLTYNMVLNLMRVEGMAVSWIINNSFHQFQSYAKIPEIDKKCVQVERKIASFNFPWENEMRTLVDLQDQLEATRQRIIQIQREPKYIVGFLHAGRLFKVKSGDRDFKWGILNQFKKEQ------NPDDRNDQIYLCDMMIAINTEGRFDPTNPATLVPGFDLPKRRWIRVPMTIDRITAISAVRLKVPADIDKPDGQ------------------MRLDGMMAAATKRFGNQIPLLDPIQDMEIKTVEMKELIAREKSLEGRLETHSMTKRDNMKDLKKQFEQKQDAVKELNALKAERKSVQSTLHLEELNNRKRVLRRLGYLGNDDALVLKGSVACELSASDELILTEMLLKGIFNTLDVAQTAALLSCFVFQDKCA-APKLATELQTCLSELHEQARNVAKVSNECKMEVMEDKYVSSFNPGLMDVVYQWVNGATFSEIVKTTDVFEGSIIRTLRRLEEVLREMINAAKALANKELEQKFEDARKNLKRDIVFAASLYL 1026

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Celegans
Match: skih-2 (SKI (Yeast SuperKIller) Helicase homolog [Source:UniProtKB/TrEMBL;Acc:Q19103])

HSP 1 Score: 426.017 bits (1094), Expect = 7.794e-130
Identity = 221/504 (43.85%), Postives = 325/504 (64.48%), Query Frame = 3

Query:  405 KAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG-----LLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQ------------------KNESNVF-KIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMV-DETMSDIDARK-IIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALI 1838
            + YPF LD FQ++++ C++  +S+ V+AHTSAGKTV+AEYAIA   + K R +YT+PIKALSNQK+R+F + F +VGL+TGD+ L P A+ LIMTTEIL+SMLY GS ++R++ WV+FDE+HY+ + ERG VWEE +++LP  ++   LSAT+PN  +FA+W+  + N+  +V+ T+ RPVPL+H+++    DG     L  ++D  G+F+   +  A +      +   E+AG      +Q                  KN+ N++  ++  +      P++VF FS+K C+  A  LA +N  ++ E  +V   F   ++ L  +DKELPQVLT   L  RG  VHH G+LPILKE VE+LF +G +K LFATETFAMG+NMPAR V+F S  K+DG+E R ++  EY QM+GRAGRRG D  GTVI++  D T+   D  K +I G    L S F +TY+M+LNL+RVE +  E M++RS+ +  +   + E++E  K+L+
Sbjct:  287 RKYPFSLDPFQQSSVLCMERGESLFVAAHTSAGKTVVAEYAIALCQAHKTRAVYTSPIKALSNQKFRDFKQIFGDVGLVTGDIQLHPEAACLIMTTEILRSMLYNGSEVIRDLEWVVFDEVHYINNEERGHVWEEVLIMLPAHVKIVMLSATVPNCVEFADWVGRIKNRKINVISTDRRPVPLEHFLY-TGQDGKTQKDLFKIIDRSGQFILKGYNDAKDSKAKIYE--KEKAGGAGGRGTQRGGGRGGGGNGGGRNWPGKNDKNIYLNLINYMKCSDQLPMVVFVFSRKRCDENAQMLASMNLTTEVEKQHVRLFFSQCVQRLKGSDKELPQVLTMRDLCLRGFAVHHSGILPILKEVVELLFQKGYVKILFATETFAMGVNMPARCVVFDSIMKHDGTERRMLNPGEYTQMAGRAGRRGLDLTGTVIIICKDSTVPQPDVLKNLISGQALRLESKFRVTYSMILNLLRVEQLKIEDMLQRSYVESDS---LRESKEKRKSLV 784

HSP 2 Score: 105.145 bits (261), Expect = 1.509e-22
Identity = 71/208 (34.13%), Postives = 109/208 (52.40%), Query Frame = 3

Query: 2616 ELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCL----------------VFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            E  +R +VL  LN+   K ++ LKGR+ CEI    ELL+TEL+L   F+  +P++ AA +S L                VF E S  + ++   L +     +++   ++D+  E R D             +M+VV  WA+G  F Q++  T   EG I++CI+ L+EV + + NA + +G+  L EK  E    I+RDIVFAASLY
Sbjct: 1074 EYHNRLKVLEALNFVEQK-MVSLKGRIGCEI-HHQELLITELILDYKFHQRSPAELAALLSTLTCQYNSGREMQFGGDTVFGEISESVKSVLTRLESVASKHKSQ---ISDLGCEIRFD-------------LMEVVYEWANGTPFYQIMEMTDCQEGLIVKCIQRLDEVCKDVRNAGRIVGDPALVEKMEEVSASIRRDIVFAASLY 1263

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Celegans
Match: snrp-200 (Putative U5 small nuclear ribonucleoprotein 200 kDa helicase [Source:UniProtKB/Swiss-Prot;Acc:Q9U2G0])

HSP 1 Score: 121.709 bits (304), Expect = 1.688e-27
Identity = 118/423 (27.90%), Postives = 189/423 (44.68%), Query Frame = 3

Query:  462 NRQSVLVSAHTSAGKTVIAEYAIAKALS-----------DKQRVIYTTPIKALSNQKYREFSEEFS----EVGLLTGDVTLSPN----ASVLIMTTEILQSMLYRGS--SIMREVGWVIFDEIHYMRDRERGVVWEESIVLL-------PDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPL-QHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRW--ISANEYIQMSGRAGRRGKDERGTVILMVDET 1637
            +++ +L+ A T AGKT +A   + + +            D+ +++Y  P+K+L  +    FS+  +     VG +TGD  +S        V++ T E    +  +G   +  + V  +I DEIH + D +RG V E  +V          DE R   LSAT+PN +  A ++      L H     YRPVPL Q Y+       L        RF       AMN++    D   E AG     +SQ                    ++VF  S+KE    A  +       D  +A++ E   +A   +   + E  + L    LL  G  +HH G+  + +  VE LF++  ++ LF+T T A G+N+PA TV+    + Y+  + RW  + A + +QM GRAGR   D+RG  IL+ + +
Sbjct:  489 SKEHLLLCAPTGAGKTNVALLTMLQEIGNHLAEDGSVKLDEFKIVYIAPMKSLVQEMVGSFSKRLAPFGITVGEMTGDAQMSKEQFMATQVIVCTPEKYDVVTRKGGERAYNQMVRLLIIDEIHLLHD-DRGPVLESIVVRTIRQMEQNHDECRLVGLSATLPNYQDVATFLRVKPEHL-HFFDNSYRPVPLEQQYIGVTEKKAL-------KRF------QAMNEVV--YDKIMEHAG-----KSQ--------------------VLVFVHSRKETAKTAKAIRDACLEKDTLSAFMRE--GSASTEILRTEAEQAKNLDLKDLLPYGFAIHHAGMNRVDRTLVEDLFADRHIQVLFSTATLAWGVNLPAHTVIIKGTQIYNPEKGRWTELGALDIMQMLGRAGRPQYDDRGEGILITNHS 867

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Celegans
Match: Y54E2A.4 (pep chromosome:WBcel235:II:14754622:14778149:1 gene:WBGene00013189.1 transcript:Y54E2A.4a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y54E2A.4)

HSP 1 Score: 112.849 bits (281), Expect = 8.850e-25
Identity = 134/556 (24.10%), Postives = 236/556 (42.45%), Query Frame = 3

Query:   99 NQNSIENVTKLSDAEILINQKRLED--FIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFE-LDNF------QKAAIKCI-DNRQSVLVSAHTSAGKTVIAEYAIAKALSDK--QRVIYTTPIKALSNQKYREFSEEFSE-----VGLLTGDVTLSPN----ASVLIMTTEILQ--SMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLP----------DEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYV--FP----CNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDE---VFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWIS--ANEYIQMSGRAGRRGKDERGTVILMVDE 1634
            N+N I +  ++   ++ +N++  ++  F  P +D         ++ +NF     L SE+    D+     + +H     +SF     +   ++ EPL   +  LK   FE + NF      Q     C+    +S L+ A T +GKT+ AE A+ + L D    +V+Y  P+K+L  ++  ++ ++F +     V  ++GDVT  P     +S+LI T E     S  +     +R VG ++ DE+H +   +RG V E  +  L           + +R   LS  + NA   AEW+  + ++ C+      RPVP+  ++  FP    C   GL                  MNK             +I+    +K                  P+++F  S+++  + A     L         +++      ++ M  + D + +L     +LP    GIG+HH GL    +  VE LF E  ++ L AT T A G+N PA  V+      +DG + +++     + +QM GRAGR   D+    ++ V +
Sbjct: 1080 NENLIIHQERIGIGKMKVNRQETQNLVFTIPIVDC--------QLTNNFQLR--LASEYFVTDDV--VVPMSLHNCILPKSFKSHTDL---LDLEPLP--IKTLKNSKFEAIYNFDYFNPIQAQVFFCLYKTDKSALIGAPTGSGKTLCAELAMFRLLQDHPGMKVVYIAPLKSLVRERVDDWKKKFEDGMGYRVVEVSGDVTPDPEELAASSILITTPEKWDGISRSWATREYVRRVGLIVLDEVHLL-GVDRGAVLEAIVSRLKMITRRSHVTEEPVRLLGLSTALANAGDVAEWLG-IPDEACYNFRPSVRPVPISVHIQGFPGQHYCPRMGL------------------MNKPAYK---------AILTYSPRK------------------PVLIFVSSRRQTRLTALAFVNLLIADHNPKQWLNMDMLELEDLMAAIKDENLKL-----TLPF---GIGMHHAGLSAHERAIVEQLFIEKKIQVLIATATLAWGINCPAHLVIVKGTEYFDGKKGKYVDFPVTDVLQMMGRAGRPQFDDSAVAVIYVQD 1563

HSP 2 Score: 65.855 bits (159), Expect = 1.813e-10
Identity = 56/193 (29.02%), Postives = 89/193 (46.11%), Query Frame = 3

Query:  462 NRQSVLVSAHTSAGKTVIAEYAIAKALSDKQ-----------RVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLSPN----ASVLIMTTEILQSMLYRGS---SIMREVGWVIFDEIHYMRDRERGVVWE-------ESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPL 953
             ++++L+ A T AGKT IA   I   + + Q           ++IY  P+KAL+ +    F +  + +GL    LTGD  LS N      +L++T E    +  + +   S++  V  +I DE+H + D ERG V E         + +    IR   LSAT+PN    A ++     +        +RPVPL
Sbjct:  326 TKENLLICAPTGAGKTNIAMLTILNTIHEHQNSRGDIMKDDFKIIYIAPMKALATEMTESFGKRLAPLGLKVKELTGDTQLSRNEVADTQMLVLTPEKWDVITRKSTSDNSLINVVRLLIIDEVHLLHD-ERGPVIETLVARTLRQVEMSQSGIRIVGLSATLPNFIDVARFLRVNPYKGLFFFDGRFRPVPL 517

HSP 3 Score: 63.5438 bits (153), Expect = 8.957e-10
Identity = 38/121 (31.40%), Postives = 61/121 (50.41%), Query Frame = 3

Query: 1347 PLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSE--YRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFH 1703
            PL +RG+G+HH GL    +  +E  F+EG +  LF T T A G+N+PA  V+      +D  +  +  +   +  Q+ GRAGR   +  G  I++   T   ID    +    +P+ S F+
Sbjct:  613 PLFQRGMGIHHAGLCRQDRILMERCFAEGHVSVLFCTATLAWGVNLPAHAVVIKGTDVFDAEKGVFTDLGVLDVQQIFGRAGRPQFENEGHGIIIT--TRDKIDKYLTMLVHQNPIESQFY 731

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Celegans
Match: Y54E2A.4 (pep chromosome:WBcel235:II:14768462:14778149:1 gene:WBGene00013189.1 transcript:Y54E2A.4b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y54E2A.4)

HSP 1 Score: 112.464 bits (280), Expect = 9.914e-25
Identity = 134/556 (24.10%), Postives = 236/556 (42.45%), Query Frame = 3

Query:   99 NQNSIENVTKLSDAEILINQKRLED--FIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFE-LDNF------QKAAIKCI-DNRQSVLVSAHTSAGKTVIAEYAIAKALSDK--QRVIYTTPIKALSNQKYREFSEEFSE-----VGLLTGDVTLSPN----ASVLIMTTEILQ--SMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLP----------DEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYV--FP----CNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDE---VFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWIS--ANEYIQMSGRAGRRGKDERGTVILMVDE 1634
            N+N I +  ++   ++ +N++  ++  F  P +D         ++ +NF     L SE+    D+     + +H     +SF     +   ++ EPL   +  LK   FE + NF      Q     C+    +S L+ A T +GKT+ AE A+ + L D    +V+Y  P+K+L  ++  ++ ++F +     V  ++GDVT  P     +S+LI T E     S  +     +R VG ++ DE+H +   +RG V E  +  L           + +R   LS  + NA   AEW+  + ++ C+      RPVP+  ++  FP    C   GL                  MNK             +I+    +K                  P+++F  S+++  + A     L         +++      ++ M  + D + +L     +LP    GIG+HH GL    +  VE LF E  ++ L AT T A G+N PA  V+      +DG + +++     + +QM GRAGR   D+    ++ V +
Sbjct:  362 NENLIIHQERIGIGKMKVNRQETQNLVFTIPIVDC--------QLTNNFQLR--LASEYFVTDDV--VVPMSLHNCILPKSFKSHTDL---LDLEPLP--IKTLKNSKFEAIYNFDYFNPIQAQVFFCLYKTDKSALIGAPTGSGKTLCAELAMFRLLQDHPGMKVVYIAPLKSLVRERVDDWKKKFEDGMGYRVVEVSGDVTPDPEELAASSILITTPEKWDGISRSWATREYVRRVGLIVLDEVHLL-GVDRGAVLEAIVSRLKMITRRSHVTEEPVRLLGLSTALANAGDVAEWLG-IPDEACYNFRPSVRPVPISVHIQGFPGQHYCPRMGL------------------MNK---------PAYKAILTYSPRK------------------PVLIFVSSRRQTRLTALAFVNLLIADHNPKQWLNMDMLELEDLMAAIKDENLKL-----TLPF---GIGMHHAGLSAHERAIVEQLFIEKKIQVLIATATLAWGINCPAHLVIVKGTEYFDGKKGKYVDFPVTDVLQMMGRAGRPQFDDSAVAVIYVQD 845

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Fly
Match: Mtr4 (gene:FBgn0001986 transcript:FBtr0080760)

HSP 1 Score: 1034.25 bits (2673), Expect = 0.000e+0
Identity = 525/975 (53.85%), Postives = 680/975 (69.74%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKL-----GPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQ----LLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            RI  H +   +S +HEVA  P  E+ PLK     P K YPF LD FQ+ AI CIDN QSVLVSAHTSAGKTV+AEYAIAK+L+ KQRVIYTTPIKALSNQK+REF++EF +VGL+TGDVT++P+AS LIMTTEIL++MLYRGS IMREVGWV+FDEIHYMRD+ERGVVWEE+++LLPD +R  FLSATIPNARQFAEW+  LH Q CHVV+T+YRP PLQHY+FP  GDG+ L+VD+KG+F EDNF +AM  L         D      G   +  +   ++N+FKIV++IME    P+I+FSFSKK+CEIYA Q+AKL+FN+ +E   VDEVF NAM+ L++ D+ LPQV   LPLLRRGIG+HHGGLLPILKET+EILF EGL+K LFATETFAMGLNMPARTVLFT+ RK+DG ++RWIS+ EYIQM+GRAGRRG D++G VILM+DE +S    R I+QG  DP+NSAFH+TYNM+LNL+RVE INPEYM+ERSF+QFQNQA +P   + ++       ++ ++ E   ASY  +   L     +   +I K   L+ F+QPGRL+KV   S+++ WG V+N K+Q       L    S T D  L++ E     AA+  D     T   +P E    EV  +    I+ IS++R+  P DLR   NR  V++ I++ K++F                     P+L+ I D+ I D  F  I   I  +EK+L  H        E I + +++K   + ++++L+ E+   RS++QM+ELK RKRVLRR+ YC   DVIE KGRVACE++ ADELL+TE++  GVFN+L   Q  A +SC V +EKSSE       LS   R++Q+ A+ +A +S EC+LD+++++Y+D FKP +MDVVL W  G +FL +   T IFEGSIIRC+R LEE+LRQ+  A+KTIGNT+LE KF E IRL+KRDIVFAASLYL
Sbjct:  110 RIVTHLLDAPKSCTHEVAAHPDQEYIPLKPFSGVPAKEYPFVLDPFQRQAILCIDNSQSVLVSAHTSAGKTVVAEYAIAKSLAAKQRVIYTTPIKALSNQKFREFTDEFKDVGLVTGDVTINPSASCLIMTTEILRNMLYRGSEIMREVGWVVFDEIHYMRDKERGVVWEETLILLPDNVRYVFLSATIPNARQFAEWVCHLHKQPCHVVYTDYRPTPLQHYIFPAGGDGIHLIVDEKGQFKEDNFTTAMAVLANAGEAGKGDQKGRHGG---IKGTNAGQTNIFKIVKMIMERNFAPVIIFSFSKKDCEIYAMQMAKLDFNTPDEKKLVDEVFNNAMDVLTEEDRRLPQVENVLPLLRRGIGIHHGGLLPILKETIEILFGEGLIKALFATETFAMGLNMPARTVLFTAPRKFDGKKFRWISSGEYIQMAGRAGRRGLDDKGIVILMIDEKVSPAVGRDIVQGKADPINSAFHLTYNMVLNLLRVEEINPEYMLERSFYQFQNQAALPGLHDQVEQKTLELNKLTIKDEHNIASYHHIRSQLDQHGKQFRQWITKPQYLLPFLQPGRLVKVAAGSQEYDWGIVLNFKKQDQSRKNPLKAEPSVTIDVLLHVSE----AAAKTGD-----TEPCKPNERGCMEVVPVAHTLITQISSIRVYFPNDLRSADNRRAVLKTIQEAKKRFPLGP-----------------PVLNPIDDMNIKDREFRDIVNTISQFEKRLEEHPLHKSPELERIHRRYQDKVTLQKQLQDLKAELKAARSLLQMDELKHRKRVLRRMGYCKPGDVIEFKGRVACELSSADELLMTEMIFNGVFNDLTAPQAVALLSCFVCDEKSSESVKSATELSGPLRSMQDLARRIAKVSTECKLDLDADTYVDKFKPFLMDVVLAWCKGSSFLAVCKMTDIFEGSIIRCMRRLEELLRQMCQASKTIGNTDLENKFSEGIRLLKRDIVFAASLYL 1055

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Fly
Match: tst (gene:FBgn0039117 transcript:FBtr0334895)

HSP 1 Score: 429.483 bits (1103), Expect = 1.517e-131
Identity = 217/488 (44.47%), Postives = 312/488 (63.93%), Query Frame = 3

Query:  384 KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNG----DGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVF-KIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETM-SDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLK 1829
            ++I  P   +PFELD FQK AI  ++ RQ V V+AHTSAGKTV+AEYAIA +  D  R IYT+PIKALSNQKYR+F + F +VGL+TGD+ + P AS LIMTTEIL+SMLY GS + R++ WVIFDE+HY+ + ERG VWEE I+LLP+ +    LSAT+PN  + A+W+     +  +V+ T  RPVPL H+++   G    D + L+VD +G++L+ N++ A+ +            G      + K E   +  ++  +    + P++ F+ S+  C+     L  ++ N+++E   V + F   +  L   D+ +PQVL     L RGIGVHH G+LPILKE VE+LF  GL+K LFATETFAMG+NMPARTV+F S +K+DG E R +   EYIQM+GRAGRRG DE GT I+M   ++   ++ R +I G P+ L S F + Y ++L  +R+E I  E +++ SF +F  +  +P  ++ L+
Sbjct:  250 EQIPCPAMDFPFELDVFQKQAILKLEQRQYVFVAAHTSAGKTVVAEYAIALSKRDLTRTIYTSPIKALSNQKYRDFRKTFKDVGLITGDLQIEPTASCLIMTTEILRSMLYCGSDVTRDLEWVIFDEVHYINNPERGHVWEEVIILLPEHVNIIMLSATVPNTLELADWVGSTKKRKVYVISTLKRPVPLTHFLYTGAGGKSRDDIFLLVDAQGKYLQGNYEKAVERKKEMQGKAKGGGGGPRNHLNAKQEQYTWIGLIDFLRRSNMMPVVAFTLSRNRCDSNLAALQSVDLNTEKEKGAVQKFFLQCLAKLKPPDRTIPQVLVLKDALERGIGVHHSGILPILKEIVEMLFQNGLVKLLFATETFAMGVNMPARTVVFDSCKKFDGLEMRNLKPGEYIQMAGRAGRRGHDETGTAIIMCKGSVPPSMELRPMILGLPEKLQSQFILRYAVILTCLRIESIKVEDIMKFSFKEFNLKLQLPTQQKQLR 737

HSP 2 Score: 132.109 bits (331), Expect = 1.003e-30
Identity = 79/194 (40.72%), Postives = 113/194 (58.25%), Query Frame = 3

Query: 2634 RVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALS---TAFRTLQN-----EAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            +VLR L Y ++ D + LKG+VACE+ G +ELL+TEL+L  +FN+L P++ AA +S LVF+ K  + P +  AL     AF  + +     E +  A I  + RL+             +++VV  WA  + F +++  TT+ EG I+RCI+ L E LR +  AA  IGN  L+ K  EA   IKRDIVF ASLY
Sbjct: 1013 KVLRALKYIDELDEVTLKGKVACEM-GQNELLITELILCNMFNDLEPAEIAALLSGLVFQAKMQDKPVIPEALKECVAAFEQINDTILAEEQRFQAAIETDNRLNFG-----------LLEVVYEWARNKPFAEIMKLTTVQEGIIVRCIQQLNETLRDVKTAAIRIGNPGLQSKMEEASAAIKRDIVFTASLY 1194

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Fly
Match: tst (gene:FBgn0039117 transcript:FBtr0084462)

HSP 1 Score: 429.483 bits (1103), Expect = 1.517e-131
Identity = 217/488 (44.47%), Postives = 312/488 (63.93%), Query Frame = 3

Query:  384 KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNG----DGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVF-KIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETM-SDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLK 1829
            ++I  P   +PFELD FQK AI  ++ RQ V V+AHTSAGKTV+AEYAIA +  D  R IYT+PIKALSNQKYR+F + F +VGL+TGD+ + P AS LIMTTEIL+SMLY GS + R++ WVIFDE+HY+ + ERG VWEE I+LLP+ +    LSAT+PN  + A+W+     +  +V+ T  RPVPL H+++   G    D + L+VD +G++L+ N++ A+ +            G      + K E   +  ++  +    + P++ F+ S+  C+     L  ++ N+++E   V + F   +  L   D+ +PQVL     L RGIGVHH G+LPILKE VE+LF  GL+K LFATETFAMG+NMPARTV+F S +K+DG E R +   EYIQM+GRAGRRG DE GT I+M   ++   ++ R +I G P+ L S F + Y ++L  +R+E I  E +++ SF +F  +  +P  ++ L+
Sbjct:  250 EQIPCPAMDFPFELDVFQKQAILKLEQRQYVFVAAHTSAGKTVVAEYAIALSKRDLTRTIYTSPIKALSNQKYRDFRKTFKDVGLITGDLQIEPTASCLIMTTEILRSMLYCGSDVTRDLEWVIFDEVHYINNPERGHVWEEVIILLPEHVNIIMLSATVPNTLELADWVGSTKKRKVYVISTLKRPVPLTHFLYTGAGGKSRDDIFLLVDAQGKYLQGNYEKAVERKKEMQGKAKGGGGGPRNHLNAKQEQYTWIGLIDFLRRSNMMPVVAFTLSRNRCDSNLAALQSVDLNTEKEKGAVQKFFLQCLAKLKPPDRTIPQVLVLKDALERGIGVHHSGILPILKEIVEMLFQNGLVKLLFATETFAMGVNMPARTVVFDSCKKFDGLEMRNLKPGEYIQMAGRAGRRGHDETGTAIIMCKGSVPPSMELRPMILGLPEKLQSQFILRYAVILTCLRIESIKVEDIMKFSFKEFNLKLQLPTQQKQLR 737

HSP 2 Score: 132.109 bits (331), Expect = 1.003e-30
Identity = 79/194 (40.72%), Postives = 113/194 (58.25%), Query Frame = 3

Query: 2634 RVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALS---TAFRTLQN-----EAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            +VLR L Y ++ D + LKG+VACE+ G +ELL+TEL+L  +FN+L P++ AA +S LVF+ K  + P +  AL     AF  + +     E +  A I  + RL+             +++VV  WA  + F +++  TT+ EG I+RCI+ L E LR +  AA  IGN  L+ K  EA   IKRDIVF ASLY
Sbjct: 1013 KVLRALKYIDELDEVTLKGKVACEM-GQNELLITELILCNMFNDLEPAEIAALLSGLVFQAKMQDKPVIPEALKECVAAFEQINDTILAEEQRFQAAIETDNRLNFG-----------LLEVVYEWARNKPFAEIMKLTTVQEGIIVRCIQQLNETLRDVKTAAIRIGNPGLQSKMEEASAAIKRDIVFTASLY 1194

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Fly
Match: obe (gene:FBgn0038344 transcript:FBtr0083147)

HSP 1 Score: 115.161 bits (287), Expect = 2.162e-25
Identity = 135/481 (28.07%), Postives = 206/481 (42.83%), Query Frame = 3

Query:  333 SFSHEVAV---PPTIEFEPLKEI-VNPLKAYPFE-------LDNFQKAAIKCI---DNRQSVLVSAHTSAGKTVIAEYAIAKALSD--KQRVIYTTPIKALSNQKYREFSEEF--SEVGL----LTGDVTLSPNA---SVLIMTTEILQSMLYRG---SSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPD--------EIRCAFLSATIPNARQFAEWISFLHNQLCHVVFT-EYRPVPLQHYV--FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLP------LLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISA--NEYIQMSGRAGRRGKDERGTVILMVDE 1634
            SF H V     PP  E  PL+ + V+ LK   +E        +  Q     C+   DN  +VL+ A T +GKT++AE AI +AL+   K +V+Y  P+KAL  ++  ++ + F  S +GL    LTGDVT    A   S LI+TT      + R       ++ V  ++ DEIH + + +RG V  E IV   +         IR   LS  + NA+  A W+    N++    F    RPVPLQ ++  FP                                       G     R        F+ +R       EP IVF  S+++  + A  L  + F + E          N  + L   + E+  +L ++        L  GIG+HH GL    ++ VE LF    ++ L AT T A G+N+PA  V+      +DG   +++     + +QM GRAGR   D  G  +++V +
Sbjct: 1296 SFQHLVLPEHHPPLTELLPLRPLPVSCLKNVVYESLYKFTHFNPIQTQIFHCLYHTDN--NVLLGAPTGSGKTIVAEIAIFRALNQNPKCKVVYIAPLKALVKERIADWEQRFQRSSLGLKVVELTGDVTPDIQAIRESQLIVTTPEKWDGISRSWQTREYVQHVSLIVIDEIHLLGE-DRGPVI-EVIVSRTNFISSHTGRAIRIVGLSTALANAQDLANWLGI--NKMGLYNFKPSVRPVPLQVHINGFP---------------------------------------GKHYCPRMATMNRPTFQAIRTY--SPCEPTIVFVSSRRQTRLTALDL--ITFVAGE---------SNPKQFLHIPEDEIELILQNIREQNLKFCLAFGIGLHHAGLQEQDRKCVEELFLNRKIQILVATATLAWGVNLPAHLVVIKGTEYFDGKVKKYVDMPITDVLQMMGRAGRPQFDNEGVAVVLVHD 1718

HSP 2 Score: 58.5362 bits (140), Expect = 3.891e-8
Identity = 32/95 (33.68%), Postives = 49/95 (51.58%), Query Frame = 3

Query: 1362 GIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISAN--EYIQMSGRAGRRGKDER--GTVILMVDE 1634
            G+ +HH G+L   ++ VE  F EG +  L  T T A G+N+PA  V+      YD     ++     + +Q+ GRAGR   D+   GT+I   D+
Sbjct:  788 GLAMHHAGMLRADRQMVEKYFVEGHISVLVCTATLAWGVNLPAHAVIIRGTDIYDAKHGSFVDLGILDVLQIFGRAGRPQFDKSGVGTIITSYDK 882

HSP 3 Score: 56.225 bits (134), Expect = 2.235e-7
Identity = 53/190 (27.89%), Postives = 90/190 (47.37%), Query Frame = 3

Query:  468 QSVLVSAHTSAGKTVIAEYAIAKALS----------DKQRVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLS----PNASVLIMTTEILQSMLYRGS---SIMREVGWVIFDEIHYMRDRERGVVWE----ESIVLLPDE---IRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPL 953
            +++LV A T AGKT +A  +I   +           D+ +++Y  P+KAL+ +    FS+    + +    LTGD+ L+        +L+ T E    +  +GS   +++  V  +I DE+H +   ERG V E     ++ L+      IR   LSAT+PN    A ++     +      + +RPVPL
Sbjct:  503 ENMLVCAPTGAGKTNVAMLSIVHTIRCHLEQGVINRDEFKIVYIAPMKALAAEMVDNFSKRLKSLQIAVRELTGDIQLTKAEMAATQILVTTPEKWDVVTRKGSGDVALISLVELLIIDEVHLLHG-ERGPVVEALVARTLRLVESSQSMIRIVGLSATLPNYIDVAHFLRVNPMKGLFYFDSRFRPVPL 691

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Fly
Match: l(3)72Ab (gene:FBgn0263599 transcript:FBtr0075527)

HSP 1 Score: 109.768 bits (273), Expect = 8.115e-24
Identity = 115/427 (26.93%), Postives = 188/427 (44.03%), Query Frame = 3

Query:  453 CIDNRQSVLVSAHTSAGKTVIAEYAIAKAL-----------SDKQRVIYTTPIKALSNQKYREFSEEFS----EVGLLTGDVTLS----PNASVLIMTTEILQSMLYRGS--SIMREVGWVIFDEIHYMRDRERGVVWE-------ESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPL-QHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLP-LLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWI--SANEYIQMSGRAGRRGKDERGTVILMVDET 1637
             +D+ +++L+ A T AGKT +A   + + +           +   ++IY  P+K+L  +    F    +     V  LTGD  L+        V++ T E    +  +G   + +  V  VI DEIH + D ERG V E        +I    +E+R   LSAT+PN +  A ++    ++        YRPV L Q Y+       L        RF        MN++    + T E AG     R+Q                    ++VF  S+KE    A  +  +    D   +++ E    +ME L    +++    T L  LL  G  +HH G+  + +  VE LF++  ++ L +T T A G+N+PA TV+    + Y+  + RW+  SA + +QM GRAGR   D +G  IL+ + +
Sbjct:  492 ALDSDENMLLCAPTGAGKTNVALLTMMREIGKHINEDGTINAQDFKIIYVAPMKSLVQEMVGNFGRRLACYNLTVSELTGDHQLTREQIAATQVIVCTPEKWDIITRKGGERTFVSLVRLVIIDEIHLLHD-ERGPVLEALVARTIRNIETTQEEVRLVGLSATLPNYQDVATFLRVKPDKGLFYFDNSYRPVSLEQQYIGVTEKKAL-------KRF------QVMNEIV--YEKTMEHAG-----RNQ--------------------VLVFVHSRKETGKTARAVRDMCLEQDTLGSFLKE-GSASMEVLRTEAEQVKN--TELKELLPYGFAIHHAGMTRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYNPEKGRWVELSALDVLQMLGRAGRPQYDTKGEGILITNHS 874

HSP 2 Score: 70.4774 bits (171), Expect = 9.280e-12
Identity = 113/504 (22.42%), Postives = 200/504 (39.68%), Query Frame = 3

Query:  333 SFSH----EVAVPPT--IEFEPLKEIVNPLKAYPFE---------LDNFQKAAIKCIDNR-QSVLVSAHTSAGKTVIAEYAIAKALSDKQ--RVIYTTPIKALSNQKYREFSEEFSEVGL----LTG----DVTLSPNASVLIMTTEILQ--SMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVL---------LPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQL---AKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRW--ISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNM 1718
            SF H    E  +PPT  ++ +PL   ++ L+   FE          +  Q      + N  ++V V A T +GK  IAE+AI +  + +   R +Y    +AL++  + ++  +F  + +    LTG    D+ L     ++I T +     S  ++    ++ V   I DE+  +   E G V E  IV          +  +IR   LSA++ +AR  A+W+    N   +      RP+PL+ ++                              G N    + R  ++           V+  +     HK  P+IVF  S+K+  + A  +   A  +   +      +E  K  +E ++D  K L + L       +G+   H GL       VE LF  G ++    +     G+++ A  V+    + Y+G  + +      + +QM GRA R  +D     +LM   +  D   + I    P P+ S  H+ + M
Sbjct: 1285 SFRHLILPEKNMPPTELLDLQPLP--ISALRQPKFESFYSQRFPQFNPIQTQVFNAVYNSDENVFVGAPTGSGKMTIAEFAIMRLFTTQSDARCVYLVSEEALADLVFADWHSKFGSLDIKVVKLTGETGTDLKLIAKGQLVITTADKWDVLSRRWKQRKNVQLVNLFIVDELQLVGGEE-GPVLE--IVCSRMRYISSQIEKQIRIVALSASLTDARDVAQWLGCNPNATFNF-HPSVRPIPLELHI-----------------------------QGYNVTHNATRIATM--------SKPVYNAILKYSAHK--PVIVFVSSRKQARLTAIDVLTYAASDLQPNRFFHAEEEDIKPFLERMTD--KTLKETLA------QGVAYLHEGLSASDHRLVEQLFDSGAVQVAVISRDLCWGMSISAHLVIIMDTQFYNGKNHSYEDYPITDVLQMIGRANRPNEDADAKCVLMCQSSKKDFFKKFI--NEPLPIES--HLDHRM 1731

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Zebrafish
Match: mtrex (Mtr4 exosome RNA helicase [Source:ZFIN;Acc:ZDB-GENE-040426-2854])

HSP 1 Score: 1046.57 bits (2705), Expect = 0.000e+0
Identity = 529/970 (54.54%), Postives = 688/970 (70.93%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKL---GPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPR-PGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            ++K  +V   E  +HEV +P   E+ PLK  V    K YPF LD FQ+ AI CIDN QSVLVSAHTSAGKTV AEYAIA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHVV+T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L   G    +T  +          K  SNVFKIV++IME   +P+I+FSFSKKECE YA Q++KL+FN+DEE   V+EVF NA +CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGLLK LFATETFAMG+NMPARTVLFTSARK+DG ++RWIS+ EYIQMSGRAGRRG DERG VI MVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   VP   + +K L   Y  + + +EE   +Y+K+ + L     +  ++IHK    + F+QPGRL+KVK++  DFGWG VVN +++        +    + L++VE L+  +     N  T +  P  P E    +V  + L  I++IS+VRL +P+DLRP  NR+ ++++I++++++F                  + +P+LD I D+ I D +  K+ +K+E++E ++  H   +  N E + K   +K     +I+  ++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADELL+TE++  G+FN+L   Q  A +SC VF+E ++EMP L   L    R +Q  AK +A +S E +L+V+ +SY++ F+PH+MDVV  WA+G +F Q+   T +FEGSIIRC+R LEE+LRQ+  AAK IGNT LE KF   I  IKRDIVFAASLYL
Sbjct:   86 KVKSEQVETVEGCTHEVVLPANEEYTPLKPRVGKAAKEYPFILDPFQREAILCIDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHHVFLSATIPNARQFAEWICHLHKQPCHVVYTDYRPTPLQHYIFPAGGDGLHLVVDENGEFREDNFNTAMQVLRDAGDTGGNTGAKWDPKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKECEAYALQVSKLDFNTDEEKKLVEEVFNNATDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKALFATETFAMGINMPARTVLFTSARKFDGKDFRWISSGEYIQMSGRAGRRGMDERGIVIFMVDEKMSPAVGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAVPGVVDRMKKLEEEYNAIRIPKEESVVTYYKIRQQLAKLGKEIEEFIHKPRYCLPFLQPGRLVKVKKEDLDFGWGVVVNFQKKS----NVKAGGDLDPLFVVEVLVHCSKDSVKNAATESARPAGPAEKGEMQVVPVILHLITSISSVRLYIPKDLRPYDNRQSMLKSIQEVQKRFP-----------------DGIPLLDPIDDMGIKDPALKKVIQKVEAFEHRMYTHPLHSDPNLEAVYKLCEKKALIAGDIKAAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLTAEQATALLSCFVFQENANEMPKLTEQLGGPLRQMQECAKRIAKVSAEAKLEVDEDSYLNQFRPHLMDVVYTWANGSSFSQICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFATGITKIKRDIVFAASLYL 1034

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Zebrafish
Match: skiv2l (SKI2 homolog, superkiller viralicidic activity 2-like [Source:ZFIN;Acc:ZDB-GENE-010430-5])

HSP 1 Score: 449.129 bits (1154), Expect = 2.747e-138
Identity = 222/474 (46.84%), Postives = 315/474 (66.46%), Query Frame = 3

Query:  384 KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESN---VFK-IVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSF 1778
            K I +P   YPFELD FQK AI  ++   SV V+AHTSAGKTV+AEYAIA +     R IYT+PIKALSNQK+R+F   F +VGLLTGDV L+P  S LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LP+ +    LSAT+PNA +F+EWI  +  +  +V+ T  RPVPL+HY++  N       L +++D  G FL   + +A+      +   ++  G+  V++     S    V++ ++  + + +  P++ F+FS+  C+  A  L  L+  +  E + +    + ++  L   D++LPQ+L    LL+RGIGVHH G+LPILKE +E+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DG+ +R +   EYIQM+GRAGRRG D  GTVI++    + D+ +   ++ G P  L+S F +TY M+LNL+RVE +    M++RSF
Sbjct:  306 KRIPDPAFKYPFELDVFQKQAILRLEAHDSVFVAAHTSAGKTVVAEYAIALSQKHMTRTIYTSPIKALSNQKFRDFKNTFGDVGLLTGDVQLNPEGSCLIMTTEILRSMLYNGSEVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPEHVSIILLSATVPNAVEFSEWIGRIKKRHIYVISTIKRPVPLEHYLYTGNSTKTQKELFMLLDATGNFLTKGYYAAVEAKKERTSKHAQSFGTKNVSQHNTTASQDRAVWQTLLNYLSQRQQTPVVAFTFSRTRCDENARSLTSLDLTTSIEKSEIHSFLQKSLTRLRGGDRQLPQILLMRDLLKRGIGVHHSGILPILKEVIEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSIRKHDGTGFRNLLPGEYIQMAGRAGRRGLDATGTVIILCKAGVHDMGELHSMMLGKPTVLHSQFRLTYTMILNLLRVEALRVTDMMKRSF 779

HSP 2 Score: 122.094 bits (305), Expect = 1.364e-27
Identity = 72/198 (36.36%), Postives = 116/198 (58.59%), Query Frame = 3

Query: 2598 SIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            S+  + E   R +VL  L Y +    ++LKGRVAC+I+ + ELL+TELL +   + L P ++AA +SCLVF + +   P +   L      +   A+ + D+  +C +   +E ++  FK  + +VV  WA G  F ++   T + EG+I+RCI+ L+EVL+++  AA+ +G++ L  K   A   I+RDIVF ASLY
Sbjct: 1051 SLTLLPEYHQRIKVLEALQYVDSSGAVQLKGRVACQIS-SHELLLTELLFENTLSPLAPEESAALLSCLVFTQNTQIEPHITNTLQEGINQVLAVAQRIGDLQRDCGIAQTAEDFVAQFKFGLTEVVYCWARGMPFAEIAQLTDVQEGTIVRCIQRLDEVLKEVRQAARIVGDSVLGSKMERASLAIRRDIVFTASLY 1247

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Zebrafish
Match: skiv2l (SKI2 homolog, superkiller viralicidic activity 2-like [Source:ZFIN;Acc:ZDB-GENE-010430-5])

HSP 1 Score: 434.106 bits (1115), Expect = 1.659e-132
Identity = 222/502 (44.22%), Postives = 315/502 (62.75%), Query Frame = 3

Query:  384 KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRE----------------------------RGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESN---VFK-IVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSF 1778
            K I +P   YPFELD FQK AI  ++   SV V+AHTSAGKTV+AEYAIA +     R IYT+PIKALSNQK+R+F   F +VGLLTGDV L+P  S LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D E                            RGVVWEE +++LP+ +    LSAT+PNA +F+EWI  +  +  +V+ T  RPVPL+HY++  N       L +++D  G FL   + +A+      +   ++  G+  V++     S    V++ ++  + + +  P++ F+FS+  C+  A  L  L+  +  E + +    + ++  L   D++LPQ+L    LL+RGIGVHH G+LPILKE +E+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DG+ +R +   EYIQM+GRAGRRG D  GTVI++    + D+ +   ++ G P  L+S F +TY M+LNL+RVE +    M++RSF
Sbjct:  306 KRIPDPAFKYPFELDVFQKQAILRLEAHDSVFVAAHTSAGKTVVAEYAIALSQKHMTRTIYTSPIKALSNQKFRDFKNTFGDVGLLTGDVQLNPEGSCLIMTTEILRSMLYNGSEVIRDLEWVIFDEVHYINDAEVNHPLINIVQFYFSLYRIQMSHNVVVFQRGVVWEEVLIMLPEHVSIILLSATVPNAVEFSEWIGRIKKRHIYVISTIKRPVPLEHYLYTGNSTKTQKELFMLLDATGNFLTKGYYAAVEAKKERTSKHAQSFGTKNVSQHNTTASQDRAVWQTLLNYLSQRQQTPVVAFTFSRTRCDENARSLTSLDLTTSIEKSEIHSFLQKSLTRLRGGDRQLPQILLMRDLLKRGIGVHHSGILPILKEVIEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSIRKHDGTGFRNLLPGEYIQMAGRAGRRGLDATGTVIILCKAGVHDMGELHSMMLGKPTVLHSQFRLTYTMILNLLRVEALRVTDMMKRSF 807

HSP 2 Score: 122.094 bits (305), Expect = 1.422e-27
Identity = 72/198 (36.36%), Postives = 116/198 (58.59%), Query Frame = 3

Query: 2598 SIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            S+  + E   R +VL  L Y +    ++LKGRVAC+I+ + ELL+TELL +   + L P ++AA +SCLVF + +   P +   L      +   A+ + D+  +C +   +E ++  FK  + +VV  WA G  F ++   T + EG+I+RCI+ L+EVL+++  AA+ +G++ L  K   A   I+RDIVF ASLY
Sbjct: 1079 SLTLLPEYHQRIKVLEALQYVDSSGAVQLKGRVACQIS-SHELLLTELLFENTLSPLAPEESAALLSCLVFTQNTQIEPHITNTLQEGINQVLAVAQRIGDLQRDCGIAQTAEDFVAQFKFGLTEVVYCWARGMPFAEIAQLTDVQEGTIVRCIQRLDEVLKEVRQAARIVGDSVLGSKMERASLAIRRDIVFTASLY 1275

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Zebrafish
Match: hfm1 (helicase for meiosis 1 [Source:ZFIN;Acc:ZDB-GENE-061207-43])

HSP 1 Score: 120.939 bits (302), Expect = 3.184e-27
Identity = 117/433 (27.02%), Postives = 181/433 (41.80%), Query Frame = 3

Query:  468 QSVLVSAHTSAGKTVIAEYAIAKALSDKQ------RVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLS-----PNASVLIMTTEILQSML--YRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL-----------PD---EIRCAFLSATIPNARQFAEWISFLHN-QLCHVVFTEYRPVPLQHYV--FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSL------PLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSD 1646
            ++ +  A T +GKTV+ E AI + L +        R +Y  PIKAL +Q+Y  + ++F  +GL    LTGD  +       +A ++  T E   SM   ++ + ++  +   + DE+H ++D+ RG   E  +  +           P+    +R   +SATIPN +  +EW+S       C  +   +RPV L+  V  FPC  +      D     L  N+K A                                I++   + K  P +VF  ++K  +  A+ LAK            D  F  ++    D  + L +   SL       L   GIG HH G+    ++  E  F+ G L  LF T T AMG+NMPA  V+  S   Y G      S  + +QM GRAGR   D   T ++M      D
Sbjct:  260 KNFVACAPTGSGKTVLFELAIVRLLIEASEPWHNVRAVYMAPIKALCSQQYDNWKQKFGPLGLKCKELTGDTEIDDFFEIQDAHLIFTTAEKWDSMTRRWKDNCLLTSIRLFLVDEVHVVKDKTRGATLEVVVSRMKTMHFYRQAINPESKASVRFVAVSATIPNIQDVSEWLSDESGPATCLEMDESHRPVKLRKVVLGFPCGSNQNEFKFD-----LSLNYKLA-------------------------------NIIQTYSDQK--PTLVFCSTRKGVQQSASVLAK------------DARFIMSI----DHKQRLVKYANSLLDAKLRDLFVYGIGYHHAGMDVSDRKITENAFTVGDLPVLFTTSTLAMGVNMPAHLVVIKSTMHYVGGACEEYSEADLLQMIGRAGRPQFDTTATAVIMTRPQTKD 638

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Zebrafish
Match: ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:NCBI gene;Acc:100332599])

HSP 1 Score: 107.842 bits (268), Expect = 4.296e-23
Identity = 111/435 (25.52%), Postives = 186/435 (42.76%), Query Frame = 3

Query:  471 SVLVSAHTSAGKTVIAEYAIAKALS--DKQRVIYTTPIKALSNQKYREFSEEFSE-----VGLLTGDVTLS----PNASVLIMTTEILQ--SMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL-------PDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFT-EYRPVPLQHYV--FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWIS--ANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAF 1700
            +VL+ A T +GKT+ AE AI +  +     +V+Y  P+KAL  ++  ++     E     V  LTGD T        A +++ T E     S  ++  S +++V  +I DEIH + + +RG V E  +             +R   LS  + NAR  A+W+     Q+    F    RPVPL+ ++  FP                                       G     R       VF+ +R       +P+++F  S+++  + A  L       D+   ++ +  +   + ++   +E    LT    L  GIG+HH GL    ++TVE LF    ++ L AT T A G+N PA  V+      YDG   R++     + +QM GRAGR   D++G  +++V +   D   + + +  P P+ S+ 
Sbjct: 1342 NVLLGAPTGSGKTIAAEMAIFRVFNMYPTSKVVYIAPLKALVRERIEDWKIRIEEKLGRKVVELTGDNTPDMRAIAQADLIVTTPEKWDGVSRSWQNRSYVQKVAILIIDEIHLLGE-DRGPVLEVIVSRTNFISSHTSKTVRVVGLSTALANARDLADWLGI--GQVGLFNFRPSVRPVPLEVHIQGFP---------------------------------------GQHYCPRMATMNKPVFQAIR--THSPAKPVLIFVSSRRQTRLTALDLIAFLATEDDPKQWLHQDEREMTDIIATI-RESNLKLT----LAFGIGMHHAGLHERDRKTVEELFVNCKIQVLIATSTLAWGVNFPAHLVIVKGTEYYDGKTRRYVDYPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYE--PFPVESSL 1725

HSP 2 Score: 61.6178 bits (148), Expect = 6.626e-9
Identity = 34/95 (35.79%), Postives = 49/95 (51.58%), Query Frame = 3

Query: 1362 GIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISAN--EYIQMSGRAGRRGKDE--RGTVILMVDE 1634
            G G+HH G+L   +  +E +FS G LK L  T T A G+N+PA  V+      YD      +     + +Q+ GRAGR   D+   GT+I   D+
Sbjct:  776 GFGIHHAGMLRQDRSLMESMFSRGYLKVLVCTATLAWGVNLPAHAVIIKGTNIYDAKRGTLVDLGILDVMQIFGRAGRPQFDKYGEGTIITTHDK 870

HSP 3 Score: 55.8398 bits (133), Expect = 3.228e-7
Identity = 65/250 (26.00%), Postives = 110/250 (44.00%), Query Frame = 3

Query:  345 EVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCI---------------DNRQSVLVSAHTSAGKTVIAEYAIAKAL-----------SDKQRVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLSPNA---SVLIMTTEILQSMLYRGS----SIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDE-------IRCAFLSATIPNARQFAEWISFLH-NQLCHVVF--TEYRPVPL 953
            EV +PP    EP+         +  ELD   +   K +               +  +++L+ A T AGKT IA   I   +            D+ +++Y  P+KAL+ +    FS+    +G+    LTGD+ L+      + +++TT     ++ R S    ++ + V  +I DE+H + + +RG V E  +     +       IR   LSAT+PN    A   +FLH N    + +  + +RPVPL
Sbjct:  437 EVEIPPN---EPMPIGFEEKAVFVSELDEIGQLVFKGMKRLNRIQSIVFETAYNTNENLLICAPTGAGKTNIAMLTILHEIRQHLQPGGVIRKDQFKIVYVAPMKALAAEMTNYFSKRLEPLGIAVKELTGDMQLTKGEILRTQMLVTTPEKWDVVTRKSVGDVALSQVVRLLILDEVHLLHE-DRGPVLESLVARTLRQVESTQSMIRILGLSATLPNYLDVA---TFLHVNPFIGLFYFDSRFRPVPL 679

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Xenopus
Match: MTREX (Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:100496866])

HSP 1 Score: 1065.83 bits (2755), Expect = 0.000e+0
Identity = 543/968 (56.10%), Postives = 697/968 (72.00%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSD-STSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAP-RPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            RIK+ +V   E  +HEVA+P   E+ PLK  V    K YPF LD FQ+ AI CIDN QSVLVSAHTSAGKTV AEY+IA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHV++T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L    D +  ++ G        K  SNVFKIV++IME   +P+I+FSFSKK+CE YA Q++KL+FN+DEE   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGLLK LFATETFAMG+NMPARTVLFTSARK+DG ++RWIS+ EYIQMSGRAGRRG DERG VILMVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   +P   E +K L   Y  +++  EE   +Y+K+ + L     +  DYIHK    + FMQPGRL+KVK + +DFGWGAVVN  ++    +K +S   D  LY+VE L+  +     N  T    P RP E    +V  + L T+ AIS+VRL +P+DLR T NR+ V+++I++++++F                  + +P+LD I D+ I D    K+ +K E++E ++ +H   N  N E + K   +K +  ++I   ++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADELL+TE++  G+FN+L   Q  A +SC VF+E SSEMP L   L+   R +Q  A+ +A +S E +L+V+ E+Y+ SF+ ++MDV+  WA+G TF Q+   T +FEGSIIRC+R LEE+LRQ+  AAK IGNT LE KF E I  IKRDIVFAASLYL
Sbjct:   91 RIKVQEVETVEGCTHEVALPADEEYVPLKPRVGKAAKEYPFVLDAFQREAILCIDNNQSVLVSAHTSAGKTVCAEYSIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDAERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPSGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGR---KGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMSKLDFNTDEEKKMVEEVFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKALFATETFAMGINMPARTVLFTSARKFDGKDFRWISSGEYIQMSGRAGRRGMDERGIVILMVDEKMSPTVGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVAEKVKKLEEQYNSIQIPNEENVVTYYKIRQQLAKLGKEIEDYIHKPKYCLPFMQPGRLVKVKSEDDDFGWGAVVNFSKKSN--VKPNSGELD-PLYVVEVLINCSKESVKNAATEAAKPARPDERGEMQVVPVMLHTLCAISSVRLYIPKDLRTTDNRQSVLKSIQEVQKRFP-----------------DGVPLLDPIDDMGIKDPGLKKVVQKTEAFEHRMYSHPLNNDPNLESLYKLCEKKAQIAVDIRAAKRELKKARTVLQMDELKCRKRVLRRLGFATASDVIEMKGRVACEISSADELLLTEMMFNGLFNDLTAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQETARRIAKVSAEAKLEVDEETYLGSFRSNLMDVLYTWANGATFAQICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 1035

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Xenopus
Match: MTREX (Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:100496866])

HSP 1 Score: 1040.41 bits (2689), Expect = 0.000e+0
Identity = 529/952 (55.57%), Postives = 683/952 (71.74%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSD-STSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAP-RPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEA 3146
            RIK+ +V   E  +HEVA+P   E+ PLK  V    K YPF LD FQ+ AI CIDN QSVLVSAHTSAGKTV AEY+IA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHV++T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L    D +  ++ G        K  SNVFKIV++IME   +P+I+FSFSKK+CE YA Q++KL+FN+DEE   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGLLK LFATETFAMG+NMPARTVLFTSARK+DG ++RWIS+ EYIQMSGRAGRRG DERG VILMVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   +P   E +K L   Y  +++  EE   +Y+K+ + L     +  DYIHK    + FMQPGRL+KVK + +DFGWGAVVN  ++    +K +S   D  LY+VE L+  +     N  T    P RP E    +V  + L T+ AIS+VRL +P+DLR T NR+ V+++I++++++F                  + +P+LD I D+ I D    K+ +K E++E ++ +H   N  N E + K   +K +  ++I   ++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADELL+TE++  G+FN+L   Q  A +SC VF+E SSEMP L   L+   R +Q  A+ +A +S E +L+V+ E+Y+ SF+ ++MDV+  WA+G TF Q+   T +FEGSIIRC+R LEE+LRQ+  AAK IGNT LE KF E 
Sbjct:   87 RIKVQEVETVEGCTHEVALPADEEYVPLKPRVGKAAKEYPFVLDAFQREAILCIDNNQSVLVSAHTSAGKTVCAEYSIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDAERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPSGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGR---KGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMSKLDFNTDEEKKMVEEVFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKALFATETFAMGINMPARTVLFTSARKFDGKDFRWISSGEYIQMSGRAGRRGMDERGIVILMVDEKMSPTVGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVAEKVKKLEEQYNSIQIPNEENVVTYYKIRQQLAKLGKEIEDYIHKPKYCLPFMQPGRLVKVKSEDDDFGWGAVVNFSKKSN--VKPNSGELD-PLYVVEVLINCSKESVKNAATEAAKPARPDERGEMQVVPVMLHTLCAISSVRLYIPKDLRTTDNRQSVLKSIQEVQKRFP-----------------DGVPLLDPIDDMGIKDPGLKKVVQKTEAFEHRMYSHPLNNDPNLESLYKLCEKKAQIAVDIRAAKRELKKARTVLQMDELKCRKRVLRRLGFATASDVIEMKGRVACEISSADELLLTEMMFNGLFNDLTAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQETARRIAKVSAEAKLEVDEETYLGSFRSNLMDVLYTWANGATFAQICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEG 1015

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Xenopus
Match: MTREX (Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:100496866])

HSP 1 Score: 993.03 bits (2566), Expect = 0.000e+0
Identity = 505/917 (55.07%), Postives = 656/917 (71.54%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSD-STSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAP-RPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEG 3041
            RIK+ +V   E  +HEVA+P   E+ PLK  V    K YPF LD FQ+ AI CIDN QSVLVSAHTSAGKTV AEY+IA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHV++T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L    D +  ++ G        K  SNVFKIV++IME   +P+I+FSFSKK+CE YA Q++KL+FN+DEE   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGLLK LFATETFAMG+NMPARTVLFTSARK+DG ++RWIS+ EYIQMSGRAGRRG DERG VILMVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   +P   E +K L   Y  +++  EE   +Y+K+ + L     +  DYIHK    + FMQPGRL+KVK + +DFGWGAVVN  ++    +K +S   D  LY+VE L+  +     N  T    P RP E    +V  + L T+ AIS+VRL +P+DLR T NR+ V+++I++++++F                  + +P+LD I D+ I D    K+ +K E++E ++ +H   N  N E + K   +K +  ++I   ++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADELL+TE++  G+FN+L   Q  A +SC VF+E SSEMP L   L+   R +Q  A+ +A +S E +L+V+ E+Y+ SF+ ++MDV+  WA+G TF Q+   T +FEG
Sbjct:   87 RIKVQEVETVEGCTHEVALPADEEYVPLKPRVGKAAKEYPFVLDAFQREAILCIDNNQSVLVSAHTSAGKTVCAEYSIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDAERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPSGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGR---KGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMSKLDFNTDEEKKMVEEVFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKALFATETFAMGINMPARTVLFTSARKFDGKDFRWISSGEYIQMSGRAGRRGMDERGIVILMVDEKMSPTVGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVAEKVKKLEEQYNSIQIPNEENVVTYYKIRQQLAKLGKEIEDYIHKPKYCLPFMQPGRLVKVKSEDDDFGWGAVVNFSKKSN--VKPNSGELD-PLYVVEVLINCSKESVKNAATEAAKPARPDERGEMQVVPVMLHTLCAISSVRLYIPKDLRTTDNRQSVLKSIQEVQKRFP-----------------DGVPLLDPIDDMGIKDPGLKKVVQKTEAFEHRMYSHPLNNDPNLESLYKLCEKKAQIAVDIRAAKRELKKARTVLQMDELKCRKRVLRRLGFATASDVIEMKGRVACEISSADELLLTEMMFNGLFNDLTAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQETARRIAKVSAEAKLEVDEETYLGSFRSNLMDVLYTWANGATFAQICKMTDVFEG 980

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Xenopus
Match: MTREX (Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:100496866])

HSP 1 Score: 921.768 bits (2381), Expect = 0.000e+0
Identity = 483/917 (52.67%), Postives = 629/917 (68.59%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSD-STSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAP-RPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEG 3041
            RIK+ +V   E  +HEVA+P   E+ PLK  V    K YPF LD FQ+ AI CIDN QSVLVSAHTSAGKTV AEY+IA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q                                 G F EDNF +AM  L    D +  ++ G        K  SNVFKIV++IME   +P+I+FSFSKK+CE YA Q++KL+FN+DEE   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGLLK LFATETFAMG+NMPARTVLFTSARK+DG ++RWIS+ EYIQMSGRAGRRG DERG VILMVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   +P   E +K L   Y  +++  EE   +Y+K+ + L     +  DYIHK    + FMQPGRL+KVK + +DFGWGAVVN  ++    +K +S   D  LY+VE L+  +     N  T    P RP E    +V  + L T+ AIS+VRL +P+DLR T NR+ V+++I++++++F                  + +P+LD I D+ I D    K+ +K E++E ++ +H   N  N E + K   +K +  ++I   ++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADELL+TE++  G+FN+L   Q  A +SC VF+E SSEMP L   L+   R +Q  A+ +A +S E +L+V+ E+Y+ SF+ ++MDV+  WA+G TF Q+   T +FEG
Sbjct:   87 RIKVQEVETVEGCTHEVALPADEEYVPLKPRVGKAAKEYPFVLDAFQREAILCIDNNQSVLVSAHTSAGKTVCAEYSIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDAERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQ---------------------------------GDFREDNFNTAMQVLRDAGDLAKGDQKGR---KGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMSKLDFNTDEEKKMVEEVFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKALFATETFAMGINMPARTVLFTSARKFDGKDFRWISSGEYIQMSGRAGRRGMDERGIVILMVDEKMSPTVGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVAEKVKKLEEQYNSIQIPNEENVVTYYKIRQQLAKLGKEIEDYIHKPKYCLPFMQPGRLVKVKSEDDDFGWGAVVNFSKKSN--VKPNSGELD-PLYVVEVLINCSKESVKNAATEAAKPARPDERGEMQVVPVMLHTLCAISSVRLYIPKDLRTTDNRQSVLKSIQEVQKRFP-----------------DGVPLLDPIDDMGIKDPGLKKVVQKTEAFEHRMYSHPLNNDPNLESLYKLCEKKAQIAVDIRAAKRELKKARTVLQMDELKCRKRVLRRLGFATASDVIEMKGRVACEISSADELLLTEMMFNGLFNDLTAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQETARRIAKVSAEAKLEVDEETYLGSFRSNLMDVLYTWANGATFAQICKMTDVFEG 947

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Xenopus
Match: SKIV2L (Ski2 like RNA helicase [Source:NCBI gene;Acc:100038207])

HSP 1 Score: 457.603 bits (1176), Expect = 3.576e-142
Identity = 232/491 (47.25%), Postives = 323/491 (65.78%), Query Frame = 3

Query:  384 KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNG----DGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMV--ARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKAL 1835
            K+I +    +PFELD FQK AI+C++   SV ++AHTSAGKTV+AEYAIA +L    R IYT+PIKALSNQK+R+F   F +VGL+TGDV L   AS LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LPD +    LSAT+PN  +FA+WI  +  +  +V+ T  RPVPL+HY++  N     +   L++D  G F    + +A+      S   S+  G+          ++     +V+ +      P++VF+FS+  CE  AT L+ ++  S  E + V   +   +  L  AD++LPQVL  L LL+RGIG+HH G+LPILKE VE+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DGS +R ++  EYIQM+GRAGRRG D  G VI++    + ++ D  K++ G P  L S F +TY+M+LNL+RVE +  E M++RSF + + Q      E+ +K L
Sbjct:  199 KQIPDLAFKHPFELDPFQKKAIQCLEAGSSVFIAAHTSAGKTVVAEYAIALSLKHMTRAIYTSPIKALSNQKFRDFKITFGDVGLITGDVQLYTGASCLIMTTEILRSMLYNGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVNIILLSATVPNTVEFADWIGRIKKKKIYVISTTRRPVPLEHYLYTGNSQKTQNQFFLLLDALGGFQTKGYYAAVEAKKERSSKYSQTFGAKHPHGVGPGHDKGTWLSLVQSLKIRDALPVVVFTFSRTRCEQNATALSTVDLCSTAEKSEVQTYYTKCLSRLRGADRQLPQVLHMLDLLKRGIGIHHSGILPILKEVVEMLFSRGLVKILFATETFAMGVNMPARTVVFDSIRKHDGSNFRDLTPGEYIQMAGRAGRRGLDNTGMVIILCKADVPEMSDLHKMMLGKPTQLQSQFRLTYSMILNLLRVEALRVEDMMKRSFAESRTQRDSKAHEQRIKLL 689

HSP 2 Score: 152.14 bits (383), Expect = 9.228e-37
Identity = 82/198 (41.41%), Postives = 121/198 (61.11%), Query Frame = 3

Query: 2598 SIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            S+  + E + R  VLR L Y +D   ++LKGRVACE++ + ELLVTEL+L G  + L P + AA +SCLVF+ K+   P L   L    + ++  A+ LA I  EC L  + E ++  +K  + +VV  WA G  F +++  T I EG I+RC++ L+E  R + +AA+ +G+  L  K   A +LIKRDI+FAASLY
Sbjct:  951 SLSLLPEYQQRVNVLRTLQYIDDGGAVQLKGRVACEVS-SHELLVTELVLDGALSPLAPEEIAALLSCLVFQHKTQCEPRLTDTLKQGVKKVRELAERLALIQRECGLRESVEDFVAQYKFGLTEVVYEWARGMPFSEIMTLTDIQEGLIVRCVQRLDEACRDVRSAARLVGDATLCAKMDAASQLIKRDIIFAASLY 1147

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Mouse
Match: Mtrex (Mtr4 exosome RNA helicase [Source:MGI Symbol;Acc:MGI:1919448])

HSP 1 Score: 1059.67 bits (2739), Expect = 0.000e+0
Identity = 537/968 (55.48%), Postives = 693/968 (71.59%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSD-STSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAP-RPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            R+K+  V   E  +HEVA+P   ++ PLK  V    K YPF LD FQ+ AI+C+DN QSVLVSAHTSAGKTV AEYAIA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHV++T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L    D +  ++ G        K  SNVFKIV++IME   +P+I+FSFSKK+CE YA Q+ KL+FN+DEE   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGL+K LFATETFAMG+NMPARTVLFT+ARKYDG ++RWIS+ EYIQMSGRAGRRG D+RG VILMVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   +P   E +K     Y ++ +  EE    Y+K+ + L     +  +YIHK    + F+QPGRL+KVK + +DFGWG VVN  ++    +K +S   D  LY+VE LL  +     N  T    P +P E    +V  + +  +SAIS VRL +P+DLRP  NR+ V+++I++++ +F                  + +P+LD I D+ I D+   K+ +K+E++E ++ +H   N  N E +      K +  L+I++ ++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADELL+TE++  G+FN+L+  Q  A +SC VF+E SSEMP L   L+   R +Q  AK +A +S E +L+++ E+Y+ SFKPH+MDVV  WA G TF  +   T +FEGSIIRC+R LEE+LRQ+  AAK IGNT LE KF E I  IKRDIVFAASLYL
Sbjct:   96 RVKVQSVETVEGCTHEVALPADEDYIPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGR---KGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKYDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEENVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSN--VKPNSGELD-PLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISTVRLYIPKDLRPVDNRQSVLKSIQEVQRRFP-----------------DGVPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCERKAQIALDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSSEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 1040

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Mouse
Match: Skiv2l (superkiller viralicidic activity 2-like (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1099835])

HSP 1 Score: 447.203 bits (1149), Expect = 1.701e-137
Identity = 253/610 (41.48%), Postives = 358/610 (58.69%), Query Frame = 3

Query:  390 IVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVF----PCNGDGLLLVVDDKGRFLEDNFKSAM----NKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESL----KALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVEC-LLTVAARPNDNKKTPTRAPRP 2177
            I  P   + FE D FQK AI  ++   SV V+AHTSAGKTV+AEYAIA A     R IYT+PIKALSNQK+R+F   F +VGLLTGDV L P AS LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LP+ +    LSAT+PNA +FA+WI  L  +  +V+ T  RPVPL+HY+F    P     L L++D +G F    + +A+     ++  ++ +   +  +     +Q     +  +  L    +L P++VF+FS+  C+  A+ L  L+  +  E + +    +  +  L  +D++LPQVL    LLRRG+GVHH G+LPILKE VE+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DGS +R +   EY+QM+GRAGRRG D  GTVIL+    + ++ D  +++ G P  L S F +TY M+LNL+RV+ +  E M++RSF +F ++      E++L    K L A  E     Q      Y+   E L          I +S   +  +  GR++ VK +      G ++ +          S++T+     LV C    V+  P D        P P
Sbjct:  297 IPQPAFQWAFEPDVFQKQAILHLEQHDSVFVAAHTSAGKTVVAEYAIALAQKHMTRTIYTSPIKALSNQKFRDFRNTFGDVGLLTGDVQLHPEASCLIMTTEILRSMLYSGSDVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPEHVSIILLSATVPNALEFADWIGRLKRRQIYVISTVARPVPLEHYLFTGNSPKTQGELFLLLDSRGAFHTQGYYAAVEAKKERMSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRAQL-PVVVFTFSRGRCDEQASGLTSLDLTTSSEKSEIHLFLQRCLARLRGSDRQLPQVLHMSELLRRGLGVHHSGILPILKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAGRAGRRGLDPTGTVILLCKGRVPEMADLHRMMMGKPSQLQSQFRLTYTMILNLLRVDALRVEDMMKRSFSEFPSRKDSKAHEQALADLTKRLGALEEPDVTGQLADLPEYYSWAEELTETQNMIQRRIMESVNGLKSLSVGRVVVVKNEEHHNALGVILQVS---------SNSTSRVFTTLVLCDKPVVSDNPRDKGPATPDVPHP 896

HSP 2 Score: 121.324 bits (303), Expect = 2.689e-27
Identity = 67/192 (34.90%), Postives = 101/192 (52.60%), Query Frame = 3

Query: 2616 ELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            E   R  VLR L Y ++   ++L GRVAC ++ + ELL+TEL+     + L P + AA +S LV +        L   L      ++  AK + ++ V C L+   E ++      +++VV  WA G  F +L   +   EG ++RCI+ L E+ R L  AA+ +G   L  K   A  L++RDIVFAASLY
Sbjct: 1052 EYHQRVEVLRTLGYVDEAGTVKLAGRVACAMS-SHELLLTELMFDNALSALRPEEIAALLSGLVCQSPGDPGDQLPSTLKQGVERVKAVAKRIGEVQVACGLNQTVEEFVGELNFGLVEVVYEWARGMPFSELAGLSGTPEGLVVRCIQRLAEMCRSLRGAARLVGEPVLGAKMETAATLLRRDIVFAASLY 1242

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Mouse
Match: Hfm1 (HFM1, ATP-dependent DNA helicase homolog [Source:MGI Symbol;Acc:MGI:3036246])

HSP 1 Score: 146.362 bits (368), Expect = 5.446e-35
Identity = 120/421 (28.50%), Postives = 187/421 (44.42%), Query Frame = 3

Query:  468 QSVLVSAHTSAGKTVIAEYAIAKALSD------KQRVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLS-----PNASVLIMTTEILQSML--YRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL--------------PDEIRCAFLSATIPNARQFAEWISFLHN-QLCHVVFTEYRPVPLQHYV--FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMV 1628
            ++ ++ A T +GKTV+ E AI + L +        +++Y  PIKAL +Q++ ++ E+F  VGL    LTGD  +       +A+++I T E   S+   +R +S ++ V   + DE+H ++D  RG   E  +  +              P  +R   +SATIPNA   AEW+S      +C  +   +RPV LQ  V  FPC+        D     L  N+K                               V+ ++R   + K  P +VF  ++K  +  A+ L K      +    V++  +      S  D +L   L        G+G HH G+    ++ VE LF+ G L  LF T T AMG+NMPA  V+  S   Y G  +   S  + +QM GRAGR   D   T ++M 
Sbjct:  296 RNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNMKIVYMAPIKALCSQRFDDWKEKFGPVGLNCKELTGDTVMDDLFEIQHANIIITTPEKWDSVTRKWRDNSFIQLVRLFLIDEVHVIKDENRGPTLEVVVSRMKTVQSLSRDLESASPVPVRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSSQTEFKFD-----LALNYK-------------------------------VYSVIRTYSDQK--PTLVFCSTRKGVQQAASVLVK----DAKFIISVEQKLRLQKSAYSIRDSKLKDTLV------YGVGYHHAGMELSDRKLVEGLFTSGDLPVLFTTSTLAMGMNMPAHLVVIKSTMHYSGGVFEEYSETDILQMIGRAGRPQFDTTATAVIMT 668

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Query:  468 QSVLVSAHTSAGKTVIAEYAIAKALSD------KQRVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLS-----PNASVLIMTTEILQSML--YRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL--------------PDEIRCAFLSATIPNARQFAEWISFLHN-QLCHVVFTEYRPVPLQHYV--FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMV 1628
            ++ ++ A T +GKTV+ E AI + L +        +++Y  PIKAL +Q++ ++ E+F  VGL    LTGD  +       +A+++I T E   S+   +R +S ++ V   + DE+H ++D  RG   E  +  +              P  +R   +SATIPNA   AEW+S      +C  +   +RPV LQ  V  FPC+        D     L  N+K                               V+ ++R   + K  P +VF  ++K  +  A+ L K      +    V++  +      S  D +L   L        G+G HH G+    ++ VE LF+ G L  LF T T AMG+NMPA  V+  S   Y G  +   S  + +QM GRAGR   D   T ++M 
Sbjct:  296 RNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNMKIVYMAPIKALCSQRFDDWKEKFGPVGLNCKELTGDTVMDDLFEIQHANIIITTPEKWDSVTRKWRDNSFIQLVRLFLIDEVHVIKDENRGPTLEVVVSRMKTVQSLSRDLESASPVPVRFVAVSATIPNAEDIAEWLSDGERPAVCLKMDESHRPVKLQKVVLGFPCSSSQTEFKFD-----LALNYK-------------------------------VYSVIRTYSDQK--PTLVFCSTRKGVQQAASVLVK----DAKFIISVEQKLRLQKSAYSIRDSKLKDTLV------YGVGYHHAGMELSDRKLVEGLFTSGDLPVLFTTSTLAMGMNMPAHLVVIKSTMHYSGGVFEEYSETDILQMIGRAGRPQFDTTATAVIMT 668

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Mouse
Match: Ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:MGI Symbol;Acc:MGI:1925237])

HSP 1 Score: 110.538 bits (275), Expect = 7.285e-24
Identity = 111/438 (25.34%), Postives = 188/438 (42.92%), Query Frame = 3

Query:  471 SVLVSAHTSAGKTVIAEYAIAKALSD--KQRVIYTTPIKALSNQKYREFSEEFSE-----VGLLTGDVTLS----PNASVLIMTTEILQ--SMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL-------PDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFT-EYRPVPLQHYV--FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVD---EVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWIS--ANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAF 1700
            +VL+ A T +GKTV AE AI +  +     + +Y  P+KAL  ++  ++     E     V  LTGDVT        A +++ T E     S  ++  S +++V  +I DEIH + + ERG V E  +             +R   LS  + NAR  A+W++    Q+    F    RPVPL+ ++  FP                                       G     R        F+ +R       +P+++F  S+++  + A +L       ++   +++   +   N +  + D++ +L         L  GIG+HH GL    ++TVE LF    ++ L AT T A G+N PA  V+      YDG   R++     + +QM GRAGR   D++G  +++V +   D   + + +  P P+ S+ 
Sbjct: 1345 NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKIRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRSYVQQVNILIIDEIHLLGE-ERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNI--KQMGLFNFRPSVRPVPLEVHIQGFP---------------------------------------GQHYCPRMASMNKPAFQAIR--SHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEQEMDNIIGTVRDSNLKLT--------LAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYE--PFPVESSL 1728

HSP 2 Score: 82.4185 bits (202), Expect = 2.916e-15
Identity = 104/425 (24.47%), Postives = 178/425 (41.88%), Query Frame = 3

Query:  459 DNRQSVLVSAHTSAGKTVIAEYAIAKAL----------SDKQRVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLSPNASVLIMTTEILQSMLYRGSSIMRE----------VGWVIFDEIHYMRDRERGVVWEESIVLLPDE-------IRCAFLSATIPNARQFAEWISFLH-NQLCHVVFTE--YRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISAN--EYIQMSGRAGRRGKDERGTVILM 1625
            +  +++L+ A T AGKT IA   I   +           ++ +++Y  P+KAL+ +    FS+    +G+    LTGD+ LS +    I+ T++L +   +   + R+          V  +I DE+H + + +RG V E  +     +       IR   LSAT+PN    A   +FLH N    + + +  +RPVPL             L +    +  + N    M+++   S     +AG  ++       + V   + LI   K    I   F   E   Y   L ++  + +++   V E+F +                        G  +HH G+L   +  VE LFS G +K L  T T A G+N+PA  V+    + Y      ++     + +Q+ GRAGR   D+ G  I++
Sbjct:  491 NTNENMLICAPTGAGKTNIAMLTILHEIRQHFHQGVIKKNEFKIVYVAPMKALAAEMTNYFSKRLEPLGIVVKELTGDMQLSKSE---ILRTQMLVTTPEKWDVVTRKSVGDVALSQIVKLLILDEVHLLHE-DRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVA---TFLHVNPYIGLFYFDGRFRPVPLGQ---------TFLGIKSTNKMQQLN---NMDEVCYESVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNSGQIS-CFLPTEGPEYGHALKQVQKSRNKQ---VRELFSD------------------------GFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVVIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIII 868

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BLAST of Superkiller viralicidic activity 2-like 2 vs. UniProt/SwissProt
Match: sp|Q9CZU3|MTREX_MOUSE (Exosome RNA helicase MTR4 OS=Mus musculus OX=10090 GN=Mtrex PE=1 SV=1)

HSP 1 Score: 1059.67 bits (2739), Expect = 0.000e+0
Identity = 537/968 (55.48%), Postives = 693/968 (71.59%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSD-STSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAP-RPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            R+K+  V   E  +HEVA+P   ++ PLK  V    K YPF LD FQ+ AI+C+DN QSVLVSAHTSAGKTV AEYAIA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHV++T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L    D +  ++ G        K  SNVFKIV++IME   +P+I+FSFSKK+CE YA Q+ KL+FN+DEE   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGL+K LFATETFAMG+NMPARTVLFT+ARKYDG ++RWIS+ EYIQMSGRAGRRG D+RG VILMVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   +P   E +K     Y ++ +  EE    Y+K+ + L     +  +YIHK    + F+QPGRL+KVK + +DFGWG VVN  ++    +K +S   D  LY+VE LL  +     N  T    P +P E    +V  + +  +SAIS VRL +P+DLRP  NR+ V+++I++++ +F                  + +P+LD I D+ I D+   K+ +K+E++E ++ +H   N  N E +      K +  L+I++ ++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADELL+TE++  G+FN+L+  Q  A +SC VF+E SSEMP L   L+   R +Q  AK +A +S E +L+++ E+Y+ SFKPH+MDVV  WA G TF  +   T +FEGSIIRC+R LEE+LRQ+  AAK IGNT LE KF E I  IKRDIVFAASLYL
Sbjct:   96 RVKVQSVETVEGCTHEVALPADEDYIPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGR---KGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKYDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEENVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSN--VKPNSGELD-PLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISTVRLYIPKDLRPVDNRQSVLKSIQEVQRRFP-----------------DGVPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCERKAQIALDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSSEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 1040

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BLAST of Superkiller viralicidic activity 2-like 2 vs. UniProt/SwissProt
Match: sp|P42285|MTREX_HUMAN (Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3)

HSP 1 Score: 1058.9 bits (2737), Expect = 0.000e+0
Identity = 535/968 (55.27%), Postives = 696/968 (71.90%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSD-STSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAP-RPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            R+K+  V   E  +HEVA+P   ++ PLK  V    K YPF LD FQ+ AI+C+DN QSVLVSAHTSAGKTV AEYAIA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHV++T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L    D +  ++ G        K  SNVFKIV++IME   +P+I+FSFSKK+CE YA Q+ KL+FN+DEE   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGL+K LFATETFAMG+NMPARTVLFT+ARK+DG ++RWIS+ EYIQMSGRAGRRG D+RG VILMVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   +P   E +K     Y ++ +  EE    Y+K+ + L     +  +YIHK    + F+QPGRL+KVK + +DFGWG VVN  ++    +K +S   D  LY+VE LL  +     N  T    P +P E    +V  + +  +SAIS+VRL +P+DLRP  NR+ V+++I++++++F                  + +P+LD I D+ I D+   K+ +K+E++E ++ +H   N  N E +     +K +  ++I++ ++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADELL+TE++  G+FN+L+  Q  A +SC VF+E SSEMP L   L+   R +Q  AK +A +S E +L+++ E+Y+ SFKPH+MDVV  WA G TF  +   T +FEGSIIRC+R LEE+LRQ+  AAK IGNT LE KF E I  IKRDIVFAASLYL
Sbjct:   98 RVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDAFQREAIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGR---KGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLPFLQPGRLVKVKNEGDDFGWGVVVNFSKKSN--VKPNSGELD-PLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSVRLYIPKDLRPVDNRQSVLKSIQEVQKRFP-----------------DGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDIKSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMPKLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 1042

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BLAST of Superkiller viralicidic activity 2-like 2 vs. UniProt/SwissProt
Match: sp|P47047|MTR4_YEAST (ATP-dependent RNA helicase DOB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MTR4 PE=1 SV=1)

HSP 1 Score: 907.516 bits (2344), Expect = 0.000e+0
Identity = 469/984 (47.66%), Postives = 669/984 (67.99%), Query Frame = 3

Query:  315 KVSGDESFSHEVAVPPTIEFEPLKEI--VNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAM----NKLG--PNSDSTSERAGSIMVARSQKNES--NVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSED-FGWGAVVN----IKRQQPQLLKYSSATTDEALYLVECLLTVAA--------RP-NDNKKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            KV       H+VA+PP  ++ P+ E   VN  + YPF LD FQ  AI CID  +SVLVSAHTSAGKTV+AEYAIA++L +KQRVIYT+PIKALSNQKYRE   EF +VGL+TGD+T++P+A  L+MTTEIL+SMLYRGS +MREV WVIFDE+HYMRD+ERGVVWEE+I+LLPD++R  FLSATIPNA +FAEWI  +H+Q CH+V+T +RP PLQHY+FP +GDG+ LVVD+K  F E+NF+ AM    N++G  PNS  +  + G      S K ++  +++KIV++I + K  P+IVFSFSK++CE  A +++KL+FNSD+E   + ++F NA+  L + D+ELPQ+   LPLLRRGIG+HH GLLPILKE +EILF EG LK LFATETF++GLNMPA+TV+FTS RK+DG ++RW+S  EYIQMSGRAGRRG D+RG VI+M+DE M    A+ +++G  D L+SAFH+ YNM+LNLMRVEGI+PE+M+E SFFQFQN   VP  E+ L  L   ++ +EVE EE    Y ++++A++         +   +  ++F+QPGRL+++  + +D +GWGAVV+    I ++ P     S+  TD   Y+V  ++            +P N       R    GE  +  V  + L +I +I  +RL MP+D+R +G +E V +++ ++  +F                  + +P+LD +K++KI+DE FLK+ +KI+    KL+++   N    EE+   +  K     +++ L+++I + +++IQ+++L+ RKRVLRRL +C   D+IELKGRVACEI+  DELL+TEL+  G FN L P Q AA +SC  F+E+  E P L P L+   + ++  A  +A I  + +++V  + Y++SF+  +M+VV  W  G TF Q+   T ++EGS+IR  + LEE++++L + A TIGN++L+EK    ++LI RDIV A SLYL
Sbjct:  112 KVRLSHQVRHQVALPPNYDYTPIAEHKRVNEARTYPFTLDPFQDTAISCIDRGESVLVSAHTSAGKTVVAEYAIAQSLKNKQRVIYTSPIKALSNQKYRELLAEFGDVGLMTGDITINPDAGCLVMTTEILRSMLYRGSEVMREVAWVIFDEVHYMRDKERGVVWEETIILLPDKVRYVFLSATIPNAMEFAEWICKIHSQPCHIVYTNFRPTPLQHYLFPAHGDGIYLVVDEKSTFREENFQKAMASISNQIGDDPNSTDSRGKKGQTYKGGSAKGDAKGDIYKIVKMIWKKKYNPVIVFSFSKRDCEELALKMSKLDFNSDDEKEALTKIFNNAIALLPETDRELPQIKHILPLLRRGIGIHHSGLLPILKEVIEILFQEGFLKVLFATETFSIGLNMPAKTVVFTSVRKWDGQQFRWVSGGEYIQMSGRAGRRGLDDRGIVIMMIDEKMEPQVAKGMVKGQADRLDSAFHLGYNMILNLMRVEGISPEFMLEHSFFQFQNVISVPVMEKKLAELKKDFDGIEVEDEENVKEYHEIEQAIKGYREDVRQVVTHPANALSFLQPGRLVEISVNGKDNYGWGAVVDFAKRINKRNP-----SAVYTDHESYIVNVVVNTMYIDSPVNLLKPFNPTLPEGIRPAEEGEKSICAVIPITLDSIKSIGNLRLYMPKDIRASGQKETVGKSLREVNRRFP-----------------DGIPVLDPVKNMKIEDEDFLKLMKKIDVLNTKLSSNPLTNSMRLEELYGKYSRKHDLHEDMKQLKRKISESQAVIQLDDLRRRKRVLRRLGFCTPNDIIELKGRVACEISSGDELLLTELIFNGNFNELKPEQAAALLSCFAFQERCKEAPRLKPELAEPLKAMREIAAKIAKIMKDSKIEVVEKDYVESFRHELMEVVYEWCRGATFTQICKMTDVYEGSLIRMFKRLEELVKELVDVANTIGNSSLKEKMEAVLKLIHRDIVSAGSLYL 1073

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BLAST of Superkiller viralicidic activity 2-like 2 vs. UniProt/SwissProt
Match: sp|O14232|MTR4_SCHPO (ATP-dependent RNA helicase mtr4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mtr4 PE=1 SV=1)

HSP 1 Score: 901.738 bits (2329), Expect = 0.000e+0
Identity = 472/968 (48.76%), Postives = 650/968 (67.15%), Query Frame = 3

Query:  342 HEVAVPPTIEFEPL---KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKL------GPNSDSTSERAGSIMVARSQKNE-SNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNI-KRQQPQLLKYSSATTDEALYLVECLLTVAARPND----NKKTPTRAPRPGEAKVA-EVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSS-EMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            H+V++PP  ++ P+   K  + P + YPF LD FQ  +I CI+ ++SVLVSAHTSAGKTV+AEYA+A++L DKQRVIYT+PIKALSNQKYRE   EF +VGL+TGDVT++P+A+ L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD+ERGVVWEE+I+LLPD+    FLSATIPNA QFAEWI+ +H Q CHVV+T++RP PLQHY+FP   DG+ LVVD+K  F E+NF+ AM+ L       P + +T   A      +      S+++KIV++IM     P+IVFSFSK+ECE  A Q++KL+ N   E   V  +F NA+  LS+ D+ELPQ+   LPLLRRGIG+HH GLLPILKE +EILF EGLLK LFATETF++GLNMPA+TV+FT+ RK+DG  +RWIS  EYIQMSGRAGRRG D+RG VILM+DE M    A+ +++G  D L+SAFH++YNM+LNL+RVEGI+PE+M+ER FFQFQN   VP+ E  L+     Y+   +  E     Y  L   L+         ++  +  ++F+Q GRL++VK  +EDF WG VVN+ KR  P+    S+    +  Y+V  L+ VA+        +   P   P   E K   EV    L ++  I+ +R+ +P DL+  G +  V + + ++K +F                  E + +LD ++++ I + +F+K+ +K+   E +L ++   N S  EE    +  K     E+++L+K++ K RSI+Q++EL SRKRVLRRL +    DVIE+KGRVACEI+  D LL+TEL+  G+FN+L P Q AA +SCLVF+EKS  E   +   L+   + LQ  A+ +A +S E + ++N E Y++SFKP +M+VV  WA G +F Q+   T ++EGS+IR  R LEE++RQ+ +AAK IGNT+L++K  + I  I RDIVF+ASLYL
Sbjct:  169 HQVSIPPNYDYVPISKHKSPIPPARTYPFTLDPFQAVSIACIERQESVLVSAHTSAGKTVVAEYAVAQSLRDKQRVIYTSPIKALSNQKYRELLAEFGDVGLMTGDVTINPDATCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDKERGVVWEETIILLPDKSHFVFLSATIPNAMQFAEWITKIHRQPCHVVYTDFRPTPLQHYLFPSGSDGIHLVVDEKSNFREENFQRAMSALMEKQGDDPAAMATKGNAKKGKTGKGGVKGPSDIYKIVKMIMVKNYNPVIVFSFSKRECEALALQMSKLDMNDQTERDLVTTIFNNAVNQLSEKDRELPQIEHILPLLRRGIGIHHSGLLPILKEVIEILFQEGLLKVLFATETFSIGLNMPAKTVVFTNVRKFDGKTFRWISGGEYIQMSGRAGRRGLDDRGIVILMIDEKMDPPVAKSMLKGEADRLDSAFHLSYNMILNLLRVEGISPEFMLERCFFQFQNSLEVPKLEAKLEESQQHYDSFTILDERPLEEYHTLKTQLERYRTDVRTVVNHPNFCLSFLQGGRLVRVKVGNEDFDWGVVVNVSKRPLPK--GQSNEYLPQESYIVHTLVMVASDTGPLRIRSGHLPEVHPPAAEDKGKFEVVPFLLSSLDGIAHIRVFLPNDLKSQGQKLTVGKALSEVKRRFP-----------------EGITLLDPVENMNIKEPTFIKLMKKVNILESRLLSNPLHNFSELEEKYAEYLRKLALLEEVKDLKKKLSKARSIMQLDELNSRKRVLRRLGFTTSDDVIEVKGRVACEISSGDGLLLTELIFNGMFNDLTPEQCAALLSCLVFQEKSEVENQRMKEELAGPLKILQEMARRIAKVSKESKQELNEEEYVNSFKPSLMEVVYAWAHGASFAQICKMTDVYEGSLIRMFRRLEELIRQMVDAAKVIGNTSLQQKMEDTIACIHRDIVFSASLYL 1117

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BLAST of Superkiller viralicidic activity 2-like 2 vs. UniProt/SwissProt
Match: sp|Q23223|MTR4_CAEEL (mRNA transport homolog 4 OS=Caenorhabditis elegans OX=6239 GN=mtr-4 PE=3 SV=1)

HSP 1 Score: 899.042 bits (2322), Expect = 0.000e+0
Identity = 471/973 (48.41%), Postives = 640/973 (65.78%), Query Frame = 3

Query:  303 IKIHKVSGD-ESFSHEVAVPPTIEFEPLKE--IVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARS---QKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTP-TRAPRPGEAKVAEVTL-LKLKTISAISAVRLVMPQDL-RPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            I +H +  D E+ +HEVA+PP  EF  L+E     P K YPF+LD FQK AI CIDN QSVLVSAHTSAGKTV+A YAIAK L +KQRVIYT+PIKALSNQKYRE  EEF +VGL+TGDVTL+P+AS L+MTTEIL+SMLYRGS IM+EVGWV++DEIHYMRD+ERGVVWEE+I+L+   I+ AFLSATIPNARQFA+W++ +  Q  +VV+T+YRP PLQH+++P  G+G+  VV+ KG F ED F+ AM+ L    DS    AGS    R+    + +SNV KI+R +  +     IVFSFS+KECE YA  L  ++FN D E   V  V+++A+  LS  D++LPQ+L  LPLLRRGIGVHH GL+PILKET+EILF EGL+K LFATETF+MGLNMPARTV+FTSARK+DGS+ R+I++ EYIQM+GRAGRRGKD+RGTVILMVD  MS  DA++II+G  DPLNS F +TYNM+LNLMRVEG+   ++I  SF QFQ+ A +PE ++    +           E    +   L + L+    + +    +   ++ F+  GRL KVK    DF WG +   K++Q      +    ++ +YL + ++ +      +   P T  P     K   + + + +  I+AISAVRL +P D+ +P G                            +       +P+LD I+D++I      ++  + +S E +L  H      N +++ K F +K+    E+  L+ E    +S + + EL +RKRVLRRL Y  + D + LKG VACE++ +DEL++TE+LLKG+FN L+ +QTAA +SC VF++K +  P L   L T    L  +A+ +A +S EC+++V  + Y+ SF P +MDVV +W +G TF ++V  T +FEGSIIR +R LEEVLR++ NAAK + N  LE+KF +A + +KRDIVFAASLYL
Sbjct:   83 IIVHTIRTDNENCTHEVAIPPNAEFAELRENSGTEPAKYYPFQLDAFQKQAILCIDNNQSVLVSAHTSAGKTVVATYAIAKCLREKQRVIYTSPIKALSNQKYRELEEEFKDVGLMTGDVTLNPDASCLVMTTEILRSMLYRGSEIMKEVGWVVYDEIHYMRDKERGVVWEETIILMSKNIKQAFLSATIPNARQFAQWVASIKQQPVNVVYTDYRPTPLQHWIYPVGGEGMYEVVNVKGEFREDKFRDAMSGLATAGDS----AGSFNKRRTGGGTQGDSNVLKIIRSVASNDGLNCIVFSFSRKECESYAISLKDMDFNKDHEKGMVKSVYESAIAQLSPEDQKLPQILNILPLLRRGIGVHHSGLMPILKETIEILFGEGLVKVLFATETFSMGLNMPARTVVFTSARKFDGSDNRYITSGEYIQMAGRAGRRGKDDRGTVILMVDSAMSADDAKQIIKGATDPLNSQFRLTYNMVLNLMRVEGMAVSWIINNSFHQFQSYAKIPEIDKKCVQVERKIASFNFPWENEMRTLVDLQDQLEATRQRIIQIQREPKYIVGFLHAGRLFKVKSGDRDFKWGILNQFKKEQ------NPDDRNDQIYLCDMMIAINTEGRFDPTNPATLVPGFDLPKRRWIRVPMTIDRITAISAVRLKVPADIDKPDGQ------------------MRLDGMMAAATKRFGNQIPLLDPIQDMEIKTVEMKELIAREKSLEGRLETHSMTKRDNMKDLKKQFEQKQDAVKELNALKAERKSVQSTLHLEELNNRKRVLRRLGYLGNDDALVLKGSVACELSASDELILTEMLLKGIFNTLDVAQTAALLSCFVFQDKCA-APKLATELQTCLSELHEQARNVAKVSNECKMEVMEDKYVSSFNPGLMDVVYQWVNGATFSEIVKTTDVFEGSIIRTLRRLEEVLREMINAAKALANKELEQKFEDARKNLKRDIVFAASLYL 1026

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BLAST of Superkiller viralicidic activity 2-like 2 vs. TrEMBL
Match: A0A4Y2HR77 (Exosome RNA helicase MTR4 OS=Araneus ventricosus OX=182803 GN=Mtrex PE=4 SV=1)

HSP 1 Score: 1100.12 bits (2844), Expect = 0.000e+0
Identity = 550/971 (56.64%), Postives = 715/971 (73.64%), Query Frame = 3

Query:  294 AARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNP-LKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQ--KNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPT-RAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            ++RI++H V   E+  HEVAVP   E+ PL++  NP  + YPF LD FQK AI C++N QSVLVSAHTSAGKTV+AEYAIA +L DKQRVIYTTPIKALSNQKYREF EEF +VGLLTGDVT++P+AS LIMTTEIL+SMLYRGS +MREVGWVIFDEIHYMRD+ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH+Q CHVV+T+YRPVPLQ Y+FP  GDGL LVVD+ G F E+NF +AM+ L       + +  S M  R    K+ SN +KIV++IME    P+IVFSFSKKECE YA Q+AKL+FN+DEE   V+EVFKNAM+ LSD DK+LPQV   LPLL+RGIG+HH GLLPILKET+EILFSEGL+K LFATETFAMGLNMPARTVLFT+ARK+DG ++RW+++ EYIQMSGRAGRRG DERG VILM+DE MS    ++I++G PDP+NSAFH+TYNM+LNL+RV+ INPEYM+ERSFFQFQN + +P+  E +K L   ++ +++++E+   SY+K+ + L +   +   +I +    + F QPGRL+KVK   +DFGWG +VN +++  Q    S+   +   Y+V+CLL V+    + K T   + P P E  V +V  +KL  I  +S VR   P+DLRP  NR +V++ I+ I E+F                    LP+LD ++D+KI +E    + ++IE++  +LN+H   N  + +++L+ +++K +   EI+  + E+ K RS++QM+ELK RKRVLRR+ YC   DVIE+KGRVACEI+ ADELL+TE++  G FNNLN  QT A +SC VF+EKS+EMP L   LS   R +Q+ A+ +A IS ECRL+++ E Y+DSFKPH+MDVV  W++G +F  +   T +FEGS+IRC+R LEE++RQ+  AAK IGNT +E KF E I+LIKRDIVFAASLYL
Sbjct:   79 SSRIQVHVVETVEACLHEVAVPHDSEYIPLRQSQNPPSRKYPFILDPFQKEAILCLENNQSVLVSAHTSAGKTVVAEYAIAMSLKDKQRVIYTTPIKALSNQKYREFYEEFKDVGLLTGDVTINPSASCLIMTTEILRSMLYRGSEVMREVGWVIFDEIHYMRDKERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHHQPCHVVYTDYRPVPLQQYIFPAGGDGLHLVVDENGNFREENFNTAMSVL--QVAGGAAKGDSAMKGRKGGFKDGSNCYKIVKMIMERNFAPVIVFSFSKKECEAYAMQMAKLDFNTDEEKPLVEEVFKNAMDVLSDEDKKLPQVEHVLPLLKRGIGIHHSGLLPILKETIEILFSEGLIKALFATETFAMGLNMPARTVLFTNARKFDGKDFRWVTSGEYIQMSGRAGRRGLDERGIVILMIDEKMSPSVGKEIVKGLPDPINSAFHLTYNMVLNLLRVDEINPEYMLERSFFQFQNYSSIPQLYEKIKTLQENHDSIKLDREDDVDSYYKIKKHLASLAEEYHYFITRPEYCVPFFQPGRLVKVKNGDDDFGWGMIVNYQKKTLQ----SANNKESVFYVVDCLLQVSKESAETKVTSNLKPPAPNEKGVMQVVPIKLNLIQQLSTVRAHTPKDLRPVDNRMQVLRTIQAILERFP-----------------NGLPLLDPVEDMKIKEEGLKDVMKRIEAFTSRLNHHPLHNDPSIDDLLEQYKKKLQIESEIKEAKAELKKARSLLQMDELKCRKRVLRRMGYCTASDVIEIKGRVACEISSADELLLTEMIFNGAFNNLNVHQTTALLSCFVFQEKSNEMPKLTEELSGPLRLMQDTARRIAKISKECRLELDLEQYVDSFKPHLMDVVYSWSNGASFAHICKMTDVFEGSVIRCMRRLEELMRQMCQAAKAIGNTEMENKFSEGIKLIKRDIVFAASLYL 1026

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BLAST of Superkiller viralicidic activity 2-like 2 vs. TrEMBL
Match: A0A4E0RHA8 (Putative cytoplasmic exosomal rna helicase ski2 dead-box superfamily protein OS=Fasciola hepatica OX=6192 GN=D915_002204 PE=4 SV=1)

HSP 1 Score: 1089.72 bits (2817), Expect = 0.000e+0
Identity = 563/1022 (55.09%), Postives = 737/1022 (72.11%), Query Frame = 3

Query:  156 QKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPL-KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLT--------VAARPNDNKKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            +++ E  ++P +D  E+ +       ++   +  L+E +  ++  K+ RIKI+K++  ES +HEVAVPP +EF+PL K+   P K YPF LD FQ+ AI CIDN QSV++SAHTSAGKT +AEYAIA AL DKQRVIYTTPIKALSNQKYREF E F EVGL+TGD T++PNAS+LIMTTEILQSMLYRG+S+MREVGWV+FDEIHYMRD ERGVVWEE++VLLPD +R  FLSATIPNARQFAEWI+ LH+Q CHVV +E+RPVPL+HY++P   +GL LV+D+ G++LEDNF  AM    P+    +E+  ++   RS   E+NV +IVRL+    LEP+IVFSFSKKECEIYA Q+AK +F ++ E   VDEVF+NA++ LS  D+ LPQV + LPLLRRG+G+HHGGLLP+LKETVEILF E L+KCLFATETFAMGLNMPARTVLFTSARKYDG  YRWI++ EYIQMSGRAGRRGKD+ GTVILMVDETM+   A++I+ G P PLNSAFHIT NMLLNL+RVE INPEYM+ERSF QFQN + +P   + L  L + +  ++VE EE   SY ++   L++   ++  YI +   ++ F+QPGRL+KV  ++ D+GWGAV+N+K++    L+   ++  E+ YL++CLL         V +  + + ++   A  P  + VAEV  +++  +  ISAVRLV+P+DLR    R  V+  I+K+K +                     LP LD + D+ I D  F++I  K++++E++L++H   +     ++LK + +KE+    IE L + +  K S+IQM EL +RKRVLRRLN+ ++ DVIELKG VACEIT ADELL+TELL  GVFN L     AA +SC VFEE++SEMP L   LS A RTLQ+ A+ +A IS ECRL V+ +SY+DSFKPH+MDVV  W  G +F Q+   T +FEG+IIR +R+LEE+LRQ+ANAA+TIG+  LE KF EAI  +KRDIVFAASLYL
Sbjct:   41 KRKAEASLKPLLDVVEEHD------PDYPQKRSKLTEDLDALEF-KSPRIKIYKIAAPESCTHEVAVPPNMEFQPLTKDSRPPAKTYPFTLDAFQQQAITCIDNNQSVMISAHTSAGKTAVAEYAIATALRDKQRVIYTTPIKALSNQKYREFYEAFPEVGLMTGDATINPNASLLIMTTEILQSMLYRGASMMREVGWVVFDEIHYMRDPERGVVWEETLVLLPDSVRYVFLSATIPNARQFAEWIAHLHHQPCHVVTSEHRPVPLRHYLYPVGSEGLFLVLDE-GKYLEDNFIRAMRSYTPDE---TEKKRTLTNKRS---ENNVVQIVRLLKHRSLEPIIVFSFSKKECEIYALQIAKFDFTTEAEKKIVDEVFRNAIDGLSAEDRALPQVESVLPLLRRGVGIHHGGLLPLLKETVEILFGENLIKCLFATETFAMGLNMPARTVLFTSARKYDGQSYRWITSGEYIQMSGRAGRRGKDDSGTVILMVDETMNGDAAKQIMMGPPPPLNSAFHITNNMLLNLLRVEEINPEYMMERSFCQFQNYSSLPMMYQELNELRSEHSVVQVEDEESVESYHQIRLCLEDLVAQQWQYIRRPQYIVPFLQPGRLVKVSTEACDYGWGAVINLKKR----LRTDRSSAPESFYLIDCLLASTSNKAAPVGSEESSDSRSAVSASEPN-SIVAEVIPIRMDCVVEISAVRLVVPKDLRAREARAGVLNAIDKVKARM-----------------GGTLPPLDPVDDMHITDAKFIEINGKVKAFEERLHHHWLHDDPRLPDLLKQYAKKEQLHKRIEQLTQTLGSKVSLIQMEELTARKRVLRRLNFVSEHDVIELKGCVACEITSADELLLTELLFDGVFNRLPSEHIAALLSCFVFEERASEMPKLTKELSDALRTLQDTARRIARISNECRLKVDEDSYVDSFKPHVMDVVYAWTRGASFAQVCAMTDLFEGTIIRTLRMLEELLRQMANAARTIGSATLEAKFNEAIEKLKRDIVFAASLYL 1026

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BLAST of Superkiller viralicidic activity 2-like 2 vs. TrEMBL
Match: K1R517 (Superkiller viralicidic activity 2-like 2 OS=Crassostrea gigas OX=29159 GN=CGI_10025938 PE=4 SV=1)

HSP 1 Score: 1072.38 bits (2772), Expect = 0.000e+0
Identity = 552/973 (56.73%), Postives = 705/973 (72.46%), Query Frame = 3

Query:  297 ARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIV-NPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKL----GPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRP-GEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEK-SSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            +RI++H+V   E+  HEVA+PP  EF PLK ++  P K YPF LD FQK A+ C++N QSVLVSAHTSAGKTV+A YAIA +L DKQRVIYT+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS IMREVGWVIFDEIHYMRD+ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH+Q CHVV+T+YRP PLQHY+FP   +G+ +VVD+ G F E+NF +AM+ L    G        R G    A     ESN F IV++IME    P+IVFSFSKK+CE YA Q++KLNFNS+EE A VDEVF NA++ LSD DK+LPQV   LPLLR+GIGVHH GLLP+LKET+EILFSEGL+K LFATETF+MGLNMPARTVLFT+ARK+DG ++RW+++ EYIQMSGRAGRRG D+RG VILMVDE +S    ++I++G  DPLNSAFH+TYNM+LNL+RVE INPEYM+ERSF+QFQN A +PE  E LK     Y ++ VE E+  ASY+K+ + L N   + + +I K   ++ F+QPGRL++VK + +DFGWGAV+N +++  Q    S A   E+ Y+VE LL ++   + +K   T  P P GE    +V  + +  I AISAVRL +P DLRP  NR+ V+++I++++++F                  + +P+LD I+D+ I ++    I +K E++E ++ +H     SN E +   ++ K +   EI  ++ E+ KK+S++QM+ELK RKRVLRR+ YC   DVIELKGRVACEI+  DELL+TELL  GVFN+L   Q  A VSC VF+E  SSE P L   LS   R +Q+ A+ +A +S+E +L++N E Y+ +FKPHMMDVV  W +G TF Q+   T IFEGSIIRC+R LEE LRQL  AAK IGN+ LE KF E IR IKRDIVFAASLYL
Sbjct:   78 SRIQVHRVETVEACLHEVAIPPEAEFVPLKPMMEKPAKEYPFILDPFQKEALLCLENNQSVLVSAHTSAGKTVVAVYAIAMSLRDKQRVIYTSPIKALSNQKYRELYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEIMREVGWVIFDEIHYMRDKERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHHQPCHVVYTDYRPTPLQHYIFPAGSNGIYMVVDENGEFREENFSTAMSVLRDAGGAAKGDQRGRRGGFKAA-----ESNCFNIVKMIMERNFAPVIVFSFSKKDCEAYALQMSKLNFNSEEEKALVDEVFNNAIDNLSDDDKKLPQVEHVLPLLRKGIGVHHSGLLPLLKETIEILFSEGLIKALFATETFSMGLNMPARTVLFTAARKFDGKDFRWVTSGEYIQMSGRAGRRGIDDRGIVILMVDEKISPSVGKQIVKGQADPLNSAFHLTYNMVLNLLRVEEINPEYMLERSFYQFQNYASIPELCEKLKDTEEKYNKLTVENEDSVASYYKIRQQLDNLGKELLTFIQKPQYILPFLQPGRLVQVKNEKDDFGWGAVINFQKKANQSKTPSGA---ESSYVVEVLLNLSRETSRSKDVNTIKPCPKGEKGEMQVVPVLVHLIQAISAVRLYIPSDLRPPDNRQSVLKSIQEVEKRFP-----------------DGIPLLDPIEDMGIKEKGLKDIVKKTEAFEHRMYSHPLHKDSNLENLYTQYQSKAQVGNEIRAIKSELKKKKSLLQMDELKCRKRVLRRMGYCTASDVIELKGRVACEISSGDELLLTELLFNGVFNDLTHQQCCALVSCFVFQENASSETPKLTEELSGPLRIMQDTARRIARVSIEAKLEMNEEDYVSTFKPHMMDVVNAWCNGATFSQICKMTNIFEGSIIRCMRRLEETLRQLMQAAKAIGNSELENKFAEGIRSIKRDIVFAASLYL 1025

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BLAST of Superkiller viralicidic activity 2-like 2 vs. TrEMBL
Match: A0A087U991 (Superkiller viralicidic activity 2-like 2 (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_08375 PE=4 SV=1)

HSP 1 Score: 1071.23 bits (2769), Expect = 0.000e+0
Identity = 546/968 (56.40%), Postives = 705/968 (72.83%), Query Frame = 3

Query:  294 AARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNP-LKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDE---ALYLVECLLTVAARPNDNKKTPTRAPRP-GEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAA 3182
            ++RI+IH V   E+  HEVAVP   E+ PL++  NP  + YPF LD FQK AI C++N QSVLVSAHTSAGKTV+AEYAIA +L DKQRVIYTTPIKALSNQKYREF EEF +VGLLTGDVT++P+AS LIMTTEIL+SMLYRGS +MREVGWV+FDEIHYMRD+ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH+Q CHVV+T+YRPVPLQ Y+FP  GDGL LVVD+ G F E+NF +AMN L     +    +G        K+ SN +KIV++IME    P+IVFSFSKKECE YA Q+AKL+FNS EE   V+EVF+NAM+ LSD DK+LPQV   LPLL+RGIG+HH GLLPILKET+EILFSEGL+K LFATETFAMGLNMPARTVLFT+ARK+DG ++RW+++ EYIQMSGRAGRRG DERG VILMVDE MS    ++I++G PDP+NSAFH+TYNM+LNL+RV+ INPEYM+ERSFFQFQN + +P+  + +K L   ++ +E+E+E+   +Y+K+ + L     +   YI +    + F QPGRL+KV+   +DFGWG V+N ++      KY +A   E     Y+V+ LL V+    + K T    P P GE  + +V  +KL  I  +S+VR   P DLRP  NR KV++ I+ I E+F                    LP+LD + D+KI D     + +KIE++  +LN+H   +  + E++L+ +++K +   EI+  + E+ K RS++QM+ELK RKRVLRR+ YC   DVIE+KGRVACEI+ ADELL+TE++  G FNNLN  QT A +SC VF+EKSSEMP L   LS   R +Q+ A+ +A IS E +L+++++ Y++SF+PH+MDVV  W+ G +F+Q+   T +FEGSIIRC+R LEE++RQ+  AAK IGNT +E KF E I+LIKRDIVFAA
Sbjct:   76 SSRIQIHVVETVEACLHEVAVPHDAEYIPLRQSQNPPSRKYPFILDPFQKEAILCLENNQSVLVSAHTSAGKTVVAEYAIAMSLRDKQRVIYTTPIKALSNQKYREFYEEFKDVGLLTGDVTINPSASCLIMTTEILRSMLYRGSEVMREVGWVVFDEIHYMRDKERGVVWEETIILLPDSVHYVFLSATIPNARQFAEWICHLHHQPCHVVYTDYRPVPLQQYIFPAGGDGLHLVVDENGNFREENFNTAMNVLQVAGGAAKGDSGMKGRKGGFKDGSNCYKIVKMIMERNFAPVIVFSFSKKECEAYAMQMAKLDFNSAEEKPLVEEVFRNAMDVLSDEDKKLPQVEHVLPLLKRGIGIHHSGLLPILKETIEILFSEGLIKALFATETFAMGLNMPARTVLFTNARKFDGKDFRWVTSGEYIQMSGRAGRRGLDERGIVILMVDEKMSPSAGKEIVKGLPDPINSAFHLTYNMVLNLLRVDEINPEYMLERSFFQFQNYSVIPQLYDKIKKLREEHDAIEIEREDEVDAYYKIKKQLATLSEEYHSYITQPEYCVPFFQPGRLVKVQNGDDDFGWGIVINYQK------KYLTAENKEESPVFYVVDVLLHVSKETAETKVTSNLKPPPSGEKGIMQVVPIKLNLIQQLSSVRAYYPDDLRPVDNRMKVLKTIQTILERFP-----------------NGLPLLDPVNDMKIKDPGLKDVLKKIEAFTSRLNHHPLHDNPSTEKLLELYKKKLQIADEIKAAKAELKKARSLLQMDELKCRKRVLRRMGYCTATDVIEIKGRVACEISSADELLLTEMIFNGAFNNLNVHQTTALLSCFVFQEKSSEMPKLGEELSGPLRLMQDTARRIAKISKESKLELDTDQYVESFRPHLMDVVHAWSKGASFMQICKMTDVFEGSIIRCMRRLEELMRQMCQAAKAIGNTEMENKFSEGIKLIKRDIVFAA 1020

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BLAST of Superkiller viralicidic activity 2-like 2 vs. TrEMBL
Match: A0A1V9XLR6 (Superkiller viralicidic activity 2 2-like (Fragment) OS=Tropilaelaps mercedesae OX=418985 GN=BIW11_09138 PE=4 SV=1)

HSP 1 Score: 1069.69 bits (2765), Expect = 0.000e+0
Identity = 542/969 (55.93%), Postives = 706/969 (72.86%), Query Frame = 3

Query:  294 AARIKIHKVSGDESFSHEVAVPPTIEFEPLK-EIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEAL-YLVECLLTVAARPNDNKKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            A+R  IH+V   +S  HEVAVP   EF PL+ +   P + YPF LD FQ+ AI CIDN QSVLVSAHTSAGKTV+AEYAIA AL +KQRVIYTTPIKALSNQKYREF EEF +VGL+TGDVT++P AS LIMTTEIL+SMLYRGS IMREVGWVIFDEIHYMRD+ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI +LH Q CHVV+TEYRPVPLQHY+FP  GDGL LVVD+KG F EDNF  AM  L   + +    +G        ++E+N +KIV++IME    P+IVFSFSK+ECE YATQ++KL+ N+ +E   V EVF NAME LSD D+ELPQV   LPLL RGI +HHGGLLPILKET+EILFSEGL+K LFATETFAMGLNMPARTVLFT+ RKYDG  +RW+++ EYIQMSGRAGRRG D+RG VILM+DE MS   A+ I++G PD +NSAFH+TYNM+LNL+RVEGINPE+M+ERSFFQFQN A +P+  + L AL    + + VE+E+  A+YFK+ + L  +  +   YI K+  ++ F+Q GR+I+VK   +DFGW  V+N K ++ Q  K ++   +E +  +VE L+ V   P   +    + P  G     +V  ++L  I  IS+VRL+ P DLRP  +R  V+++I +++++F                 ++ +P+LD I+D+ I + +  ++ ++I + E++L +       N E + K++  K++   +++  + +I K +S++QM+ELK RKRVLRRL YCN+ DVI++KGR+ACEI+ ADELL+TE++   VFNNLNP+Q  A +SCLVF+EKS+EMP L   L    R +Q+ A+ +A +S + +L+++ E YID +KPH+MDVV RW+ G +F Q+   T  FEGSIIRC+R LEE+LRQ+  AAK+IGNT LE KF EAI+LIKRDIVFAASLYL
Sbjct:   38 ASRSSIHRVDTVDSCLHEVAVPSDQEFVPLEVKQGPPAREYPFVLDPFQREAILCIDNEQSVLVSAHTSAGKTVVAEYAIALALKNKQRVIYTTPIKALSNQKYREFYEEFKDVGLMTGDVTINPTASCLIMTTEILRSMLYRGSEIMREVGWVIFDEIHYMRDKERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICYLHKQPCHVVYTEYRPVPLQHYIFPAGGDGLHLVVDEKGVFKEDNFNLAMTTLQNAAGNAKGDSGLRGRQGGFRSETNCYKIVKMIMERDYSPVIVFSFSKRECESYATQMSKLDLNTADEKKLVGEVFNNAMEALSDEDRELPQVQNVLPLLMRGIAIHHGGLLPILKETIEILFSEGLIKALFATETFAMGLNMPARTVLFTNPRKYDGQNFRWVTSGEYIQMSGRAGRRGLDDRGIVILMIDEKMSSQAAKDIVKGAPDAINSAFHLTYNMVLNLLRVEGINPEFMLERSFFQFQNYASIPQLYQRLDALQEQLDGITVEREDEVATYFKVKQQLTKSQSELRGYITKAQYIVPFLQAGRMIRVKNKKDDFGWAIVINYKNKKVQAKKPTNILDEEDVQVIVEALIYVC--PGSTEVESIKPPPKGVKGEMQVVPIRLDLIERISSVRLLYPSDLRPLDSRMSVLKSITEVEKRF-----------------DKKVPLLDPIEDMDIQEPAVKELVKQIAALEERLWSLPLHTEPNLETLYKAYAGKQQVADQVKQCKVDIRKGKSLLQMDELKCRKRVLRRLGYCNNADVIDVKGRIACEISTADELLLTEMIFNNVFNNLNPAQCNAVLSCLVFQEKSNEMPKLTEELMQPLRLMQDMARRIAQVSRDSKLEISEEDYIDQYKPHLMDVVFRWSKGSSFGQICKMTDAFEGSIIRCMRRLEELLRQMVQAAKSIGNTELETKFSEAIKLIKRDIVFAASLYL 987

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Cavefish
Match: mtrex (Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:103046062])

HSP 1 Score: 962.6 bits (2487), Expect = 0.000e+0
Identity = 490/926 (52.92%), Postives = 653/926 (70.52%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKL----------GPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDN-KKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEG 3041
            ++K+ +V   E  +HEVA+P   E++ L + V    K YPF LD FQ+ A+ CIDN QSVLVSAHTSAGKTV AEYAIA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHVV+T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L          G   D+   R G+       K  SNVFKIV++IME   +P+I+FSFSKKECE YA Q++KL+FN+D+E   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGLLK LFATETFAMG+NMPARTVLFTSARK+DG ++RWIS+ EYIQMSGRAGRRG DERG VI MVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   VP   E +K L   Y  +E+  EE   +Y+K+ + L     +  ++I K    + F+QPGRL+KVK++  +FGWG +VN  R+    +K ++   D  LY+VE L+  +     N      +    GE    +V  + L  +++IS+VRL +P+DLRP  NR+ ++++I++++++F                  + LP+LD I D+ I D +  K+ +KIE++E ++  H   +  N E +     +K     +I+++++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADEL++TE++  G+FN+L   Q  A +SC VF+E ++EMP L   L+   R +Q  A+ +A +S E +L V+ E+Y++ F+PH+MDVV  WA+G +F Q+   T +FEG
Sbjct:   88 KVKVEQVETVEGCTHEVALPADQEYKQLSQRVGKAAKEYPFILDPFQREALLCIDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVVYTDYRPTPLQHYIFPAGGDGLHLVVDENGEFREDNFNTAMQVLRDAGDQGGSSGGKWDAKGRRGGT-------KGPSNVFKIVKMIMERNFQPVIIFSFSKKECEAYALQVSKLDFNTDDEKKLVEEVFSNAIDCLSDDDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKALFATETFAMGINMPARTVLFTSARKFDGKDFRWISSGEYIQMSGRAGRRGMDERGIVIFMVDEKMSPAVGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAVPGVLEKMKKLEEMYNGIEIPNEESVVTYYKIRQQLAKLGKEIEEFIQKPKYCLPFLQPGRLVKVKKEDMEFGWGVIVNFSRKSN--VKANTGELD-PLYVVEVLVHCSKDSVKNAATEAAKPAAAGEKGEMQVIPVMLNLLTSISSVRLYIPKDLRPYDNRQSMLKSIQEVQKRFP-----------------DGLPLLDPIDDMGIKDPALKKVIQKIEAFEHRMYTHPLHSDPNLETLYTLCEKKALVAGDIKSVKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELILTEMVFNGLFNDLTAEQATALLSCFVFQENANEMPKLTEQLAAPLRQMQECARRIAKVSAEAKLTVDEETYLNQFRPHLMDVVYTWANGASFSQICKMTDVFEG 986

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Cavefish
Match: mtrex (Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:103046062])

HSP 1 Score: 959.133 bits (2478), Expect = 0.000e+0
Identity = 489/925 (52.86%), Postives = 652/925 (70.49%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKL----------GPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDN-KKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFE 3038
            ++K+ +V   E  +HEVA+P   E++ L + V    K YPF LD FQ+ A+ CIDN QSVLVSAHTSAGKTV AEYAIA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHVV+T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L          G   D+   R G+       K  SNVFKIV++IME   +P+I+FSFSKKECE YA Q++KL+FN+D+E   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGLLK LFATETFAMG+NMPARTVLFTSARK+DG ++RWIS+ EYIQMSGRAGRRG DERG VI MVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   VP   E +K L   Y  +E+  EE   +Y+K+ + L     +  ++I K    + F+QPGRL+KVK++  +FGWG +VN  R+    +K ++   D  LY+VE L+  +     N      +    GE    +V  + L  +++IS+VRL +P+DLRP  NR+ ++++I++++++F                  + LP+LD I D+ I D +  K+ +KIE++E ++  H   +  N E +     +K     +I+++++E+ K R+++QM+ELK RKRVLRRL +    DVIE+KGRVACEI+ ADEL++TE++  G+FN+L   Q  A +SC VF+E ++EMP L   L+   R +Q  A+ +A +S E +L V+ E+Y++ F+PH+MDVV  WA+G +F Q+   T +FE
Sbjct:   73 KVKVEQVETVEGCTHEVALPADQEYKQLSQRVGKAAKEYPFILDPFQREALLCIDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVVYTDYRPTPLQHYIFPAGGDGLHLVVDENGEFREDNFNTAMQVLRDAGDQGGSSGGKWDAKGRRGGT-------KGPSNVFKIVKMIMERNFQPVIIFSFSKKECEAYALQVSKLDFNTDDEKKLVEEVFSNAIDCLSDDDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKALFATETFAMGINMPARTVLFTSARKFDGKDFRWISSGEYIQMSGRAGRRGMDERGIVIFMVDEKMSPAVGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAVPGVLEKMKKLEEMYNGIEIPNEESVVTYYKIRQQLAKLGKEIEEFIQKPKYCLPFLQPGRLVKVKKEDMEFGWGVIVNFSRKSN--VKANTGELD-PLYVVEVLVHCSKDSVKNAATEAAKPAAAGEKGEMQVIPVMLNLLTSISSVRLYIPKDLRPYDNRQSMLKSIQEVQKRFP-----------------DGLPLLDPIDDMGIKDPALKKVIQKIEAFEHRMYTHPLHSDPNLETLYTLCEKKALVAGDIKSVKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELILTEMVFNGLFNDLTAEQATALLSCFVFQENANEMPKLTEQLAAPLRQMQECARRIAKVSAEAKLTVDEETYLNQFRPHLMDVVYTWANGASFSQICKMTDVFE 970

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Cavefish
Match: skiv2l (Ski2 like RNA helicase [Source:NCBI gene;Acc:103028968])

HSP 1 Score: 450.669 bits (1158), Expect = 6.101e-139
Identity = 226/476 (47.48%), Postives = 313/476 (65.76%), Query Frame = 3

Query:  384 KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKN-----ESNVFK-IVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSF 1778
            K I +P   YPFELD FQK AI  ++   SV V+AHTSAGKTV+AEYAIA +     R IYT+PIKALSNQK+R+F   F +VGLLTGDV L+P AS LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LP+ +    LSAT+PNA +F+EWI  +  +  +V+ T  RPVPL+HY++  N       L L+++  G FL   + +A+       + TS+ A S     +  N     +  +++ ++  + + +  P++ F+FS+  C+  +  L  L+  S  E   +   F  ++  L   D++LPQ+L    LL+RGIGVHH G+LPILKE +E+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DG+ +R +   EYIQM+GRAGRRG D  GTVI++    + D+ D   ++ G P  L S F +TY M+LNL+RVE +    M+ RSF
Sbjct:  307 KRIPDPAFKYPFELDTFQKQAILRLEVHDSVFVAAHTSAGKTVVAEYAIALSQKHMTRTIYTSPIKALSNQKFRDFKNTFGDVGLLTGDVQLNPEASCLIMTTEILRSMLYNGSEVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPEHVSIILLSATVPNAVEFSEWIGRIKKKPIYVISTVKRPVPLEHYLYTGNSTKTQKELFLLLEATGSFLTKGYYAAVEA---KKERTSKHAQSFGAKNAAHNTTLSQDRAIWQTLLNYLSQRQQTPVVAFTFSRTRCDDNSRSLNSLDLTSSVEKNEIHSFFHKSLSRLRGGDRQLPQILVMRDLLKRGIGVHHSGILPILKEVIEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSIRKHDGTGFRNLLPGEYIQMAGRAGRRGLDATGTVIILCKSGVHDMGDLHAMMLGKPTVLQSQFRLTYTMILNLLRVEALRVTDMMRRSF 779

HSP 2 Score: 123.635 bits (309), Expect = 4.114e-28
Identity = 72/198 (36.36%), Postives = 119/198 (60.10%), Query Frame = 3

Query: 2598 SIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            S+  + E   R +VL+ L Y ++ D ++LKGRVAC+I+ + ELL+TELL +   + L P ++AA +SCLVF + +   P +   +      +   A+ + ++  EC +   +E Y+  FK  + +VV  WA G  F ++   T + EG+++RCI+ L+EVL+++  AA+ +G++ L  K   A   I+RDIVF ASLY
Sbjct: 1051 SLTLLPEYNQRIKVLKELKYIDESDAVQLKGRVACQIS-SHELLLTELLFENTLSPLAPEESAALLSCLVFTQNTQIEPHIPNTIQEGIDRVLCVAQRIGELQRECGIAQTAEDYVSQFKFGLTEVVYCWARGMPFAEIAMLTDVQEGTVVRCIQRLDEVLKEVRQAARIVGDSVLGSKMERASLAIRRDIVFTASLY 1247

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Cavefish
Match: hfm1 (helicase for meiosis 1 [Source:ZFIN;Acc:ZDB-GENE-061207-43])

HSP 1 Score: 118.242 bits (295), Expect = 1.955e-26
Identity = 118/449 (26.28%), Postives = 187/449 (41.65%), Query Frame = 3

Query:  402 LKAYPFELDNFQKAAIKCIDN----RQSVLVSAHTSAGKTVIAEYAIAKALSDKQ------RVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLS-----PNASVLIMTTEILQSML--YRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL-----------PD---EIRCAFLSATIPNARQFAEWISFLHN-QLCHVVFTEYRPVPLQHYV--FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTS--LPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMV 1628
             K +P+    F     K +D+     ++ +  A T +GKTV+ E AI + L +        + +Y  PIKAL +Q+Y  +  +F  +GL    LTGD  +       +A +++ T E   SM   ++ + +++ V   + DE+H ++D  RG   E  +  +           PD    +R   +SATIPN    A+W+S       C  +   +RPV L+  V  FP                    F ++ N+   +     + A  I     QK                  P +VF  ++K  +  AT LAK            D  F  +++      K    +L +    L+  G+G HH G+    ++ VE  F+ G L  LF T T AMG+N+PA  V+  S   Y G      S  + +QM GRAGR   D   T ++M 
Sbjct:  236 FKEFPY----FNYVQSKALDDILYTSKNFVACAPTGSGKTVLFELAIIRLLMETTEPWHNVKAVYMAPIKALCSQQYENWKLKFGPLGLNCKELTGDTEIEDVFEIQDAHLIMTTPEKWDSMTRKWKNNCLLQSVQLFLIDEVHVVKDSTRGPTLEVVVSRMKTIHSYTVAESPDASTRMRFVAVSATIPNICDIADWLSNDQGPATCLEMDESHRPVKLRKVVLGFP--------------------FGNSQNEFKFDLSLNYKMASVIQTYSDQK------------------PTLVFCSTRKGVQQSATVLAK------------DARFIMSIDHRQRLMKYASSILDAKLRDLIMCGVGYHHAGVSLSDRKVVEDAFTAGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYAGGSCEEYSEADMLQMIGRAGRPQFDTSATAVIMT 630

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Cavefish
Match: polq (DNA polymerase theta [Source:NCBI gene;Acc:103039702])

HSP 1 Score: 109.383 bits (272), Expect = 1.242e-23
Identity = 121/467 (25.91%), Postives = 202/467 (43.25%), Query Frame = 3

Query:  468 QSVLVSAHTSAGKTVIAEYAIAK-ALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNAS-------VLIMTTEILQSMLYR--GSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL----------------PDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIME--HKLEPLIVFSFSKKECEIYATQLAKLNFN----SDEETAYVDEVFKNAMECLSDADKELPQVLTSL-PLLRR----GIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAF------HITYNMLLNLMRV 1739
            ++++ SA TSAGKT+++E  I K  L  +++ I+  P  +++ +K       F E G+       S +A+       V + T E    ++ R      M  +G V+ DE+H + D  RG + E  +  +                 D ++   +SAT+PN    A W+S    +L H   T+YRPVPL  +V       +   + D    L   F  A+   G +                         IV L  E  H     ++F  SK  CE  A  +A+  +N      +  + V  V  N +E L D   +L +    L  +L+R    G+  HH GL    ++ +E  F +G ++ L AT T + G+N+PAR V+  +   ++G     ++   Y QM GRAGR+G D  G  +L+  E    +    +IQG+  P++S         +T +ML  ++ +
Sbjct:  286 KNLVYSAPTSAGKTLVSELLILKRVLETRRKAIFILPFVSVAREKMFYLQNVFQEAGVRVEGYMGSTSAAGGFSALDVAVCTIEKANGLINRLIEEDRMDLLGIVVVDELHMLGDSGRGYLLELLLTKIQYIATKTKERCTDKAYTDGVQIVGMSATLPNLDLLARWLSA---ELYH---TDYRPVPLMEWV------KIGTQIYDGSMTLIRQFTPALPVKGDDD-----------------------HIVSLCFETVHAGHSALLFCPSKNWCEKLADSIAREFYNLYHKEKQSESGVQSVSLN-LEGLQDVVAQLKRSPAGLDQVLQRTVPWGVAFHHAGLTFDERDILEGAFRQGFIRVLAATSTLSSGVNLPARRVIIRTP-VFNGHLLDILT---YKQMVGRAGRKGVDTIGESVLVCKEA-ERMKGVSLIQGSLKPISSCLVKREGEGVTTSMLRAILEI 711

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Sea Lamprey
Match: mtrex (Mtr4 exosome RNA helicase [Source:ZFIN;Acc:ZDB-GENE-040426-2854])

HSP 1 Score: 910.598 bits (2352), Expect = 0.000e+0
Identity = 479/919 (52.12%), Postives = 622/919 (67.68%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRD--RERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPT-RAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGS 3044
            R+K  +V   E  +HEVA+     +E LK  V  P K YPF LD FQ+ AI CIDN QSVLV+AHTSAGKTV AEYAIA+AL  KQRVI+T+PIKALSNQKYRE  EEF +VGLLTGD+T++P+AS L+MTTEIL+SMLYRGS IMREV WVIFDEIHYMR+  +ERGVVWEE+I+LLPD +   FLSATIPN  QFAEWI  LH Q CHVV T+YRP PLQH++FP  GDGLLLVVD+   F EDNF  AM+ L    D + +R G        K ESNVFKI++LIME  L+P+I+FSFSK+ECE YA QL++L+FN++EE   V+EVF NAM CLSD D++LPQV   LP+L+RGIG+HHGGLLP+LKET+EILFSEGL+K LFATETFAMG+NMPARTVLFTSARK+DG ++RWIS+ EYIQMSGRAGRRG DERGTVILMVDE MS     +++QG+PDPLNSAFH+TYNM+LNL+RVE INPEYM+E+SFFQFQ    VP+    L+AL   Y  + V     A SY+ +++ LQ  + +      +    ++ +QPGRL++V    E FGWG VVN +R+          + +E   +VE LL  +     N  T   R P+P E    +V  + L+ + AIS VRL MP DLR    R  V++ ++++K +F                  + +P++D + D+ I D     +  K  ++ ++   H        + I      K +   E+  + KE+ +   ++QM+ELK RKRVLRRL +C   DVI++KGRVACEIT   ELL+TEL+ +G+FN L+P Q AA +SC VF+EK+SE P L   L+   R ++  A+ +  +SVE +L    ++ +D  +P +MDVV  WA G++F  +   T  FEG+
Sbjct:   88 RVKTVRVETLEGCTHEVAIAQESAYETLKPRVGLPAKEYPFLLDPFQREAILCIDNSQSVLVAAHTSAGKTVCAEYAIAQALRGKQRVIFTSPIKALSNQKYRELHEEFHDVGLLTGDITINPSASCLVMTTEILRSMLYRGSEIMREVAWVIFDEIHYMRNPGKERGVVWEETIILLPDNVHYVFLSATIPNGTQFAEWICHLHKQPCHVVSTDYRPTPLQHFIFPAGGDGLLLVVDEFLDFKEDNFLQAMSLLREGGDPSRKRKGG------NKGESNVFKIIKLIMERNLQPVIIFSFSKRECETYAVQLSQLDFNTEEEKCLVEEVFNNAMSCLSDEDQKLPQVQRVLPILKRGIGIHHGGLLPVLKETIEILFSEGLIKALFATETFAMGINMPARTVLFTSARKFDGRDHRWISSGEYIQMSGRAGRRGMDERGTVILMVDEKMSPTVGHQLLQGSPDPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFFQFQQYKAVPDLLAKLQALQGRYAALSVPDAASATSYYHIEQQLQRLHVEARAITLRPQHCLHVLQPGRLVQVTHGKEHFGWGVVVNFQRK--------PTSQEEFTLVVEALLLCSEESVRNAATEAPRPPQPKERGELQVVPVALELVEAISTVRLYMPPDLRTPEARHHVLKTLQEVKARFP-----------------DGVPLMDPVHDLGIKDPELEAVLHKTRAFAQRRLAHPLHTSPQRDAIRDICVSKAQVAEEVRAVRKEVRRAHMMLQMDELKRRKRVLRRLGFCTQADVIQVKGRVACEITAGHELLLTELVFEGLFNELSPEQAAALLSCFVFQEKASETPKLATDLAEPLRKMKECARRIGHVSVEAKLLGREDALLDDIRPQLMDVVYSWALGESFFTITTMTDAFEGT 975

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Sea Lamprey
Match: ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:NCBI gene;Acc:100332599])

HSP 1 Score: 107.457 bits (267), Expect = 7.579e-24
Identity = 111/441 (25.17%), Postives = 186/441 (42.18%), Query Frame = 3

Query:  471 SVLVSAHTSAGKTVIAEYAIAKALSDK--QRVIYTTPIKALSNQKYREFSEEFS-EVGL-------LTGDVTLSP----NASVLIMTTEILQ--SMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL-------PDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVF-TEYRPVPLQHYV--FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSD--EETAYVDEV-FKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWIS--ANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAF 1700
            +VL+ A T +GKTV AE AI +  +     + +Y  P+KAL  ++  ++      E G        LTGDVT       +A +++ T E     S  +   S +++V  ++ DEIH + D +RG V E  +             +R   LS  + NAR  A+W++    Q+    F    RPVPL+ ++  FP                                       G     R        F+ +R       +P+++F  S+++  + A  L       D  ++  + DE   ++ +  + D++ +L         L  GIG+HH GL    + TVE LF    ++ L AT T A G+N PA  V+      +DG   R++     + +QM GRAGR   D++G  ++ V +   D   + + +  P P+ S+ 
Sbjct:  712 NVLLGAPTGSGKTVAAELAIFRIFNAHPGAKAVYIAPLKALVRERMEDWKVRLEPEAGCAAARVVELTGDVTPDARAIASADLIVTTPEKWDGVSRSWHSRSYVKQVALLVIDEIHLLGD-DRGPVLEVIVSRTNFISSHTEKPVRVVGLSTALANARDLADWLAI--KQVILFNFRPSVRPVPLEAHIHGFP---------------------------------------GQHYCPRMATMNKPTFQAIR--THSPAKPVLIFVSSRRQTRLTALDLIAFLAGEDNPKQWLHTDETEMEHIISTVKDSNLKL--------CLAFGIGMHHAGLHERDRRTVEELFVNTRIQVLIATSTLAWGVNFPAHLVIIKGTEYFDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVIFVHDLKKDFYKKFLYE--PFPVESSL 1098

HSP 2 Score: 61.6178 bits (148), Expect = 9.652e-10
Identity = 34/94 (36.17%), Postives = 49/94 (52.13%), Query Frame = 3

Query: 1350 LLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWI--SANEYIQMSGRAGRRGKDERGTVILM 1625
            L   G   HH G+L   +  VE LFS GL++ L  T T A G+N+PA  V+    + YD     ++   A + +Q+ GRAGR   D  G  I++
Sbjct:  140 LFPDGFSTHHAGMLRPDRSLVEGLFSRGLVRVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGTFVDLGALDVMQIFGRAGRPQYDTFGLGIII 233

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Sea Lamprey
Match: ascc3 (activating signal cointegrator 1 complex subunit 3 [Source:NCBI gene;Acc:100332599])

HSP 1 Score: 107.071 bits (266), Expect = 1.202e-23
Identity = 110/443 (24.83%), Postives = 186/443 (41.99%), Query Frame = 3

Query:  471 SVLVSAHTSAGKTVIAEYAIAKALSDK--QRVIYTTPIKALSNQKYREFSEEF----------SEVGLLTGDVTLSP----NASVLIMTTEILQ--SMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL-------PDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVF-TEYRPVPLQHYV--FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSD--EETAYVDEV-FKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWIS--ANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAF 1700
            +VL+ A T +GKTV AE AI +  +     + +Y  P+KAL  ++  ++              + V  LTGDVT       +A +++ T E     S  +   S +++V  ++ DEIH + D +RG V E  +             +R   LS  + NAR  A+W++    Q+    F    RPVPL+ ++  FP                                       G     R        F+ +R       +P+++F  S+++  + A  L       D  ++  + DE   ++ +  + D++ +L         L  GIG+HH GL    + TVE LF    ++ L AT T A G+N PA  V+      +DG   R++     + +QM GRAGR   D++G  ++ V +   D   + + +  P P+ S+ 
Sbjct:  711 NVLLGAPTGSGKTVAAELAIFRIFNAHPGAKAVYIAPLKALVRERMEDWKVRLEPEAGKECAAARVVELTGDVTPDARAIASADLIVTTPEKWDGVSRSWHSRSYVKQVALLVIDEIHLLGD-DRGPVLEVIVSRTNFISSHTEKPVRVVGLSTALANARDLADWLAI--KQVILFNFRPSVRPVPLEAHIHGFP---------------------------------------GQHYCPRMATMNKPTFQAIR--THSPAKPVLIFVSSRRQTRLTALDLIAFLAGEDNPKQWLHTDETEMEHIISTVKDSNLKL--------CLAFGIGMHHAGLHERDRRTVEELFVNTRIQVLIATSTLAWGVNFPAHLVIIKGTEYFDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVIFVHDLKKDFYKKFLYE--PFPVESSL 1099

HSP 2 Score: 61.6178 bits (148), Expect = 8.945e-10
Identity = 34/94 (36.17%), Postives = 49/94 (52.13%), Query Frame = 3

Query: 1350 LLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWI--SANEYIQMSGRAGRRGKDERGTVILM 1625
            L   G   HH G+L   +  VE LFS GL++ L  T T A G+N+PA  V+    + YD     ++   A + +Q+ GRAGR   D  G  I++
Sbjct:  141 LFPDGFSTHHAGMLRPDRSLVEGLFSRGLVRVLVCTATLAWGVNLPAHAVIIKGTQIYDAKRGTFVDLGALDVMQIFGRAGRPQYDTFGLGIII 234

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Sea Lamprey
Match: helq (helicase, POLQ like [Source:ZFIN;Acc:ZDB-GENE-060503-421])

HSP 1 Score: 97.0561 bits (240), Expect = 1.143e-20
Identity = 116/435 (26.67%), Postives = 187/435 (42.99%), Query Frame = 3

Query:  444 AIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQR-VIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNA----------SVLIMTTE----ILQSMLYRGSSIMREVGWVIFDEIHYMRDR-ERGVVWEESIVLL---PDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVD---------DKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEH-KLEPLIVFSFSKKECEIYATQLAK------LNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRR----GIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVD 1631
            ++  +   ++++ S  TS GKT++AE  + + L  K+R  +   P  A+  +K R  S    E+ +   +   S             S+ I T E    ++ S+L  G   M+E+G ++ DE+H + +   RG   E+++  +       +   +SAT+ N     +   FL+ +L      ++RPV L+ Y+    GD +  V +         D  R L   + S M K+ P+                         IV L+ E       +VF  +KK CE  A  + K      L    +E+ A + E+          AD EL       P+LRR    G+  HH GL    +  +E  +S G L  L  T T A G+N+PAR V+  S   Y G+ +  +S ++Y QM GRAGR G D  G  I +V+
Sbjct:   96 SLNSVRQGKNLIYSLPTSGGKTLVAEILMLRELLCKRRDALLILPYVAIVQEKVRSLSVFGVELEIFIEEYAGSKGRMPPRKKRKKNSLYIATIEKAHSLVNSLLEEGR--MQEIGLIVVDELHMLGEGGSRGATLEQTLAKVQYTSKTTQIIGMSATLSNINDLQK---FLNAEL---YTNDFRPVELREYIKL--GDSIYGVNNKALCPEEQFDFIRLLSYKYSSGMLKMDPD------------------------HIVALVTEVIPAHSCLVFCPTKKNCENVAEMICKYLAKTFLQHREEEKRALLAEL---------QADGEL------CPVLRRTVPYGLAYHHSGLTGEERRLIEEAYSAGTLCLLTCTSTLAAGVNLPARRVILRSP--YIGNSF--LSRSQYKQMVGRAGRAGIDSSGESITIVN 477

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Sea Lamprey
Match: helq (helicase, POLQ like [Source:ZFIN;Acc:ZDB-GENE-060503-421])

HSP 1 Score: 83.9593 bits (206), Expect = 1.005e-16
Identity = 96/336 (28.57%), Postives = 149/336 (44.35%), Query Frame = 3

Query:  672 SVLIMTTE----ILQSMLYRGSSIMREVGWVIFDEIHYMRDR-ERGVVWEESIVLL---PDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNF---KSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEH-KLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRR----GIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVD 1631
            S+ I T E    ++ S+L  G   M+E+G ++ DE+H + +   RG   E+++  +       +   +SAT+ N     +   FL+ +L      ++RPV L+ Y+    GD +   V++K    E+ F   +    K+ P+                         IV L+ E       +VF  +KK CE  A  + K        T +  E  K A+     AD EL       P+LRR    G+  HH GL    +  +E  +S G L  L  T T A G+N+PAR V+  S   Y G+ +  +S ++Y QM GRAGR G D  G  I +V+
Sbjct:  117 SLYIATIEKAHSLVNSLLEEGR--MQEIGLIVVDELHMLGEGGSRGATLEQTLAKVQYTSKTTQIIGMSATLSNINDLQK---FLNAEL---YTNDFRPVELREYIKL--GDSIY-GVNNKALCPEEQFDFIRLLSYKMDPD------------------------HIVALVTEVIPAHSCLVFCPTKKNCENVAEMICKY-LAKTRHTLHHREEEKRALLAELQADGEL------CPVLRRTVPYGLAYHHSGLTGEERRLIEEAYSAGTLCLLTCTSTLAAGVNLPARRVILRSP--YIGNSF--LSRSQYKQMVGRAGRAGIDSSGESITIVN 406

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Yeast
Match: MTR4 (ATP-dependent 3'-5' RNA helicase of the DExD/H family; involved in nuclear RNA processing and degradation both as a component of TRAMP complex and in TRAMP-independent processes; TRAMP unwinds RNA duplexes, with Mtr4p unwinding activity stimulated by Pap2p/Air2p but not dependent on ongoing polyadenylation; contains an arch domain, with two coiled-coil arms/stalks and a globular fist/KOW domain, which has RNA binding activity and is required for 5.8S rRNA processing [Source:SGD;Acc:S000003586])

HSP 1 Score: 907.516 bits (2344), Expect = 0.000e+0
Identity = 469/984 (47.66%), Postives = 669/984 (67.99%), Query Frame = 3

Query:  315 KVSGDESFSHEVAVPPTIEFEPLKEI--VNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAM----NKLG--PNSDSTSERAGSIMVARSQKNES--NVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSED-FGWGAVVN----IKRQQPQLLKYSSATTDEALYLVECLLTVAA--------RP-NDNKKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            KV       H+VA+PP  ++ P+ E   VN  + YPF LD FQ  AI CID  +SVLVSAHTSAGKTV+AEYAIA++L +KQRVIYT+PIKALSNQKYRE   EF +VGL+TGD+T++P+A  L+MTTEIL+SMLYRGS +MREV WVIFDE+HYMRD+ERGVVWEE+I+LLPD++R  FLSATIPNA +FAEWI  +H+Q CH+V+T +RP PLQHY+FP +GDG+ LVVD+K  F E+NF+ AM    N++G  PNS  +  + G      S K ++  +++KIV++I + K  P+IVFSFSK++CE  A +++KL+FNSD+E   + ++F NA+  L + D+ELPQ+   LPLLRRGIG+HH GLLPILKE +EILF EG LK LFATETF++GLNMPA+TV+FTS RK+DG ++RW+S  EYIQMSGRAGRRG D+RG VI+M+DE M    A+ +++G  D L+SAFH+ YNM+LNLMRVEGI+PE+M+E SFFQFQN   VP  E+ L  L   ++ +EVE EE    Y ++++A++         +   +  ++F+QPGRL+++  + +D +GWGAVV+    I ++ P     S+  TD   Y+V  ++            +P N       R    GE  +  V  + L +I +I  +RL MP+D+R +G +E V +++ ++  +F                  + +P+LD +K++KI+DE FLK+ +KI+    KL+++   N    EE+   +  K     +++ L+++I + +++IQ+++L+ RKRVLRRL +C   D+IELKGRVACEI+  DELL+TEL+  G FN L P Q AA +SC  F+E+  E P L P L+   + ++  A  +A I  + +++V  + Y++SF+  +M+VV  W  G TF Q+   T ++EGS+IR  + LEE++++L + A TIGN++L+EK    ++LI RDIV A SLYL
Sbjct:  112 KVRLSHQVRHQVALPPNYDYTPIAEHKRVNEARTYPFTLDPFQDTAISCIDRGESVLVSAHTSAGKTVVAEYAIAQSLKNKQRVIYTSPIKALSNQKYRELLAEFGDVGLMTGDITINPDAGCLVMTTEILRSMLYRGSEVMREVAWVIFDEVHYMRDKERGVVWEETIILLPDKVRYVFLSATIPNAMEFAEWICKIHSQPCHIVYTNFRPTPLQHYLFPAHGDGIYLVVDEKSTFREENFQKAMASISNQIGDDPNSTDSRGKKGQTYKGGSAKGDAKGDIYKIVKMIWKKKYNPVIVFSFSKRDCEELALKMSKLDFNSDDEKEALTKIFNNAIALLPETDRELPQIKHILPLLRRGIGIHHSGLLPILKEVIEILFQEGFLKVLFATETFSIGLNMPAKTVVFTSVRKWDGQQFRWVSGGEYIQMSGRAGRRGLDDRGIVIMMIDEKMEPQVAKGMVKGQADRLDSAFHLGYNMILNLMRVEGISPEFMLEHSFFQFQNVISVPVMEKKLAELKKDFDGIEVEDEENVKEYHEIEQAIKGYREDVRQVVTHPANALSFLQPGRLVEISVNGKDNYGWGAVVDFAKRINKRNP-----SAVYTDHESYIVNVVVNTMYIDSPVNLLKPFNPTLPEGIRPAEEGEKSICAVIPITLDSIKSIGNLRLYMPKDIRASGQKETVGKSLREVNRRFP-----------------DGIPVLDPVKNMKIEDEDFLKLMKKIDVLNTKLSSNPLTNSMRLEELYGKYSRKHDLHEDMKQLKRKISESQAVIQLDDLRRRKRVLRRLGFCTPNDIIELKGRVACEISSGDELLLTELIFNGNFNELKPEQAAALLSCFAFQERCKEAPRLKPELAEPLKAMREIAAKIAKIMKDSKIEVVEKDYVESFRHELMEVVYEWCRGATFTQICKMTDVYEGSLIRMFKRLEELVKELVDVANTIGNSSLKEKMEAVLKLIHRDIVSAGSLYL 1073

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Yeast
Match: SKI2 (Ski complex component and putative RNA helicase; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, SKIV2L, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome [Source:SGD;Acc:S000004390])

HSP 1 Score: 446.432 bits (1147), Expect = 6.043e-138
Identity = 258/637 (40.50%), Postives = 375/637 (58.87%), Query Frame = 3

Query:  279 IDIGKAARIKIHKVSGDESFSHEVAVPPTIE-FEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEV--GLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKL------GPNSDSTSERAGSIMVARSQKNESNVF--------------------------------------------KIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMV-DETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXX----XXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSED 2015
            ID G+   +    V   + ++H V +   IE F+ L  I NP +++PFELD FQK A+  ++   SV V+AHTSAGKTV+AEYAIA A  +  + IYT+PIKALSNQK+R+F E F +V  GL+TGDV ++P+A+ LIMTTEIL+SMLYRG+ ++R+V +VIFDE+HY+ D++RGVVWEE I++LP  ++   LSAT+PN  +FA WI     +  +V+ T  RPVPL+  ++      L+ V++    FLE NF+     L      G  S + + R GS   AR  +  SN                                              +IV  + + +L P++VF FSKK CE YA  L  +NF +++E + +    + ++  L   D++LPQ+L +  LL RGI VHHGGLLPI+KE +EILFS+G +K LFATETFAMGLN+P RTV+F+S RK+DG+  R ++  E+ QM+GRAGRRG D  GTVI+M  +  +S    +++  G P  L S F +TYNM+LNL+R+E +  E MI+ SF +   +   PE E+ +K L    + +E +     +     + +L  A + A    M  + KS  +++ ++ GRL+   RD  D
Sbjct:  284 IDFGRTKPVS-KSVPVKKEWAHVVDLNHKIENFDEL--IPNPARSWPFELDTFQKEAVYHLEQGDSVFVAAHTSAGKTVVAEYAIAMAHRNMTKTIYTSPIKALSNQKFRDFKETFDDVNIGLITGDVQINPDANCLIMTTEILRSMLYRGADLIRDVEFVIFDEVHYVNDQDRGVVWEEVIIMLPQHVKFILLSATVPNTYEFANWIGRTKQKNIYVISTPKRPVPLEINIWA--KKELIPVINQNSEFLEANFRKHKEILNGESAKGAPSKTDNGRGGS--TARGGRGGSNTRDGRGGRGNSTRGGANRGGSRGAGAIGSNKRKFFTQDGPSKKTWPEIVNYLRKRELLPMVVFVFSKKRCEEYADWLEGINFCNNKEKSQIHMFIEKSITRLKKEDRDLPQILKTRSLLERGIAVHHGGLLPIVKELIEILFSKGFIKVLFATETFAMGLNLPTRTVIFSSIRKHDGNGLRELTPGEFTQMAGRAGRRGLDSTGTVIVMAYNSPLSIATFKEVTMGVPTRLQSQFRLTYNMILNLLRIEALRVEEMIKYSFSENAKETLQPEHEKQIKVLQEELQTIEYKSCEICDNDIEKFLELMLAYKEATVNLMQEMVKSPSILHILKEGRLVAF-RDPND 912

HSP 2 Score: 114.005 bits (284), Expect = 5.075e-26
Identity = 67/197 (34.01%), Postives = 109/197 (55.33%), Query Frame = 3

Query: 2616 ELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKS--SEMPTLNPALSTAFRTLQNEAKILADI--SVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            + + R  VL+   + +    + LKGRVACEI    EL++TEL+L     +  P +  A +S  V+E K+   E P + P L+   + ++   K +  +  + +  L  +   ++D  +  MM+VV  WA G +F +++  +   EG+++R I  L+E+ R++  A+  IGN+ L  K   A  LIKRDIVFAASLYL
Sbjct: 1091 DYEKRLAVLKDTEFIDQNHNVLLKGRVACEINSGYELVLTELILDNFLGSFEPEEIVALLSVFVYEGKTREEEPPIVTPRLAKGKQRIEEIYKKMLCVFNTHQIPLTQDEAEFLDRKRFAMMNVVYEWARGLSFKEIMEMSPEAEGTVVRVITWLDEICREVKTASIIIGNSTLHMKMSRAQELIKRDIVFAASLYL 1287

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Yeast
Match: HFM1 (Meiosis specific DNA helicase; involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity [Source:SGD;Acc:S000003220])

HSP 1 Score: 113.235 bits (282), Expect = 9.198e-26
Identity = 128/490 (26.12%), Postives = 209/490 (42.65%), Query Frame = 3

Query:  420 ELDNFQKAAIKCI-DNRQSVLVSAHTSAGKTVIAEYAIAKAL------SDKQRVIYTTPIKALSNQKYREFSEEFS--EVGLLTGDVTL-----SPNASVLIMTTEILQSMLYRGSSIMRE---VGWVIFDEIHYMRDRERGVVWEESIVL-----LPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFT---EYRPVPLQHYV----FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAF 1802
            E +  Q  A   I ++ ++ ++S+ T +GKTV+ E AI + +      ++  ++IY  P K+L  + Y+ +   F    VG+LT D +      +   +++I T E    +  R S   R    V  V+ DEIH ++++ RG   E  ++L     +   IR   LSAT+PN    A W+   +N+L   + +    YR V L  +V    F C  D     + +  + +E   K A N+  P       RA +I  A+             L+  H      +FS SKK C          N N        D++    M+                    +GI  HH G+    +  VE  F  G +  L +T T A+G+N+PA  V+    + ++ SE +  S  + +QM GRAGR   +  G  ++M D  M       +I GT D L S+ H+  N++ +L     +   Y IE +    +N  F
Sbjct:  138 EFNKMQSEAFPSIYESNENCIISSPTGSGKTVLFELAILRLIKETNSDTNNTKIIYIAPTKSLCYEMYKNWFPSFVNLSVGMLTSDTSFLETEKAKKCNIIITTPEKWDLLTRRWSDYSRLFELVKLVLVDEIHTIKEK-RGASLE--VILTRMNTMCQNIRFVALSATVPNIEDLALWLK-TNNELPANILSFDESYRQVQLTKFVYGYSFNCKNDFQKDAIYN-SKLIEIIEKHADNR--PVLIFCPTRASTISTAKF------------LLNNH------IFSKSKKRC----------NHNPS------DKILNECMQ--------------------QGIAFHHAGISLEDRTAVEKEFLAGSINILCSTSTLAVGVNLPAYLVIIKGTKSWNSSEIQEYSDLDVLQMIGRAGRPQFETHGCAVIMTDSKMKQT-YENLIHGT-DVLESSLHL--NLIEHLAAETSLETVYSIETAVNWLRNTFF 562

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Yeast
Match: BRR2 (RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD [Source:SGD;Acc:S000000974])

HSP 1 Score: 113.235 bits (282), Expect = 1.180e-25
Identity = 138/481 (28.69%), Postives = 204/481 (42.41%), Query Frame = 3

Query:  345 EVAVP----PTIEFEPLKEIVN----PLKAYP----FELDNFQ-KAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQ------------RVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLS----PNASVLIMTTEILQSMLYRGS---SIMREVGWVIFDEIHYMRDRERGVVWEESIVLLP--------DEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRR----GIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRW--ISANEYIQMSGRAGRRGKDERGTVILMVDET 1637
            E+ +P    P I++E LKEI +      +A+P      L+  Q K      +   ++L+ A T +GKT IA   + KALS               +++Y  P+KAL  ++ REF    + +G+    LTGD  LS        VL+ T E    +  R S   +I+  V  +I DEIH + D +RG V E SIV           +  R   LSAT+PN      ++      L +   + +RP PL                    +F     ++++ KL   +D+  E+    +      NE N               +IVF  S+KE    AT L     N   E     ++ KN          E   VL   P LR+    GIG HH GL    +   E LF++GLL+ L  T T A G+N+PA TV+      Y   +  W  +S  + +QM GRAGR   D  G  I++ D++
Sbjct:  462 EIHIPAPSKPVIDYE-LKEITSLPDWCQEAFPSSETTSLNPIQSKVFHAAFEGDSNMLICAPTGSGKTNIALLTVLKALSHHYNPKTKKLNLSAFKIVYIAPLKALVQEQVREFQRRLAFLGIKVAELTGDSRLSRKQIDETQVLVSTPEKW-DITTRNSNNLAIVELVRLLIIDEIHLLHD-DRGPVLE-SIVARTFWASKYGQEYPRIIGLSATLPNYEDVGRFLRVPKEGLFYFD-SSFRPCPLSQ------------------QFCGIKERNSLKKLKAMNDACYEKVLESI------NEGN--------------QIIVFVHSRKETSRTATWLK----NKFAEENITHKLTKNDAGSKQILKTEAANVLD--PSLRKLIESGIGTHHAGLTRSDRSLSEDLFADGLLQVLVCTATLAWGVNLPAHTVIIKGTDVYSPEKGSWEQLSPQDVLQMLGRAGRPRYDTFGEGIIITDQS 893

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Yeast
Match: SLH1 (Putative RNA helicase related to Ski2p; involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses [Source:SGD;Acc:S000003503])

HSP 1 Score: 109.383 bits (272), Expect = 1.900e-24
Identity = 113/449 (25.17%), Postives = 194/449 (43.21%), Query Frame = 3

Query:  378 PLKEIVNPL--KAYPFELDN-FQKAAIKCIDN-RQSVLVSAHTSAGKTVIAEYAIAKALSD--KQRVIYTTPIKALSNQKYREFSEEFS-----EVGLLTGDVTLSP----NASVLIMTTEILQ--SMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL-------PDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYV--FPCN-GDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGS--EYRWISANEYIQMSGRAGRRGKDERGTVILMVDET 1637
            P   + NPL    YPF+  N  Q      + N  ++  V + T +GKT++AE AI  A      ++++Y  P+KAL  ++  ++ ++ +     +V  LTGD    P    +A+++I T E     S  ++    +++V  +I DEIH +   +RG + E  +  +          +R   +S  + NA   A W+    + L +   +  RPVPL+ Y+  FP N     L+   +K  F+      A+ +  P      ++   I VA  ++       ++ L                  C +       LN + +EE  Y        +  ++D   +L         L+ GIG+HH GL+   +     LF +  ++ L AT T A G+N+PA  V+    + +D     YR +   + +QM GRAGR   D  GT I+   E+
Sbjct: 1122 PTSALQNPLIESIYPFKYFNPMQTMTFYTLYNTNENAFVGSPTGSGKTIVAELAIWHAFKTFPGKKIVYIAPMKALVRERVDDWRKKITPVTGDKVVELTGDSLPDPKDVHDATIVITTPEKFDGISRNWQTRKFVQDVSLIIMDEIHLLAS-DRGPILEMIVSRMNYISSQTKQPVRLLGMSTAVSNAYDMAGWLGVKDHGLYNFP-SSVRPVPLKMYIDGFPDNLAFCPLMKTMNKPVFM------AIKQHSP------DKPALIFVASRRQTRLTALDLIHL------------------CGMEDNPRRFLNIDDEEELQYY-------LSQVTDDTLKLS--------LQFGIGLHHAGLVQKDRSISHQLFQKNKIQILIATSTLAWGVNLPAHLVIIKGTQFFDAKIEGYRDMDLTDILQMMGRAGRPAYDTTGTAIVYTKES 1523

HSP 2 Score: 90.8929 bits (224), Expect = 7.478e-19
Identity = 99/419 (23.63%), Postives = 181/419 (43.20%), Query Frame = 3

Query:  408 AYPFELDNFQKAAIKCI--DNRQSVLVSAHTSAGKTVIAEYAIAKALS---------------DKQRVIYTTPIKALSNQKYREFSEEFS----EVGLLTGDVTLSPN---ASVLIMTTEILQSMLYRGSS----IMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDE-------IRCAFLSATIPNARQFAEWISFLHNQLCHVVFTE-YRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVF---KNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWI 1547
             +P+E  N  ++ +  +     +++L+ A T AGKT IA   I   +                D  +VIY  P+KAL+ +   +FS++ +    +V  LTGD+ L+     A+ +I+TT     ++ R ++    ++ +V  +I DE+H + + +RG V E  +     +       IR   LSAT+PN    A+++  ++ Q+    F + +RP PL+  +  C G                  K+   +   N D  +    S M+ R  +                   ++VF  S+KE    A    KL  ++ E   +  +     K +   + + DK++ ++       + G G+HH G+    +   E +F +G +K L  T T A G+N+PA  V+    + YD  +  +I
Sbjct:  282 VFPYETLNQIQSLVYPVAYKTNENMLICAPTGAGKTDIALLTIINTIKQFSVVNGENEIDIQYDDFKVIYVAPLKALAAEIVDKFSKKLAPFNIQVRELTGDMQLTKAEILATQVIVTTPEKWDVVTRKANGDNDLVSKVKLLIIDEVHLLHE-DRGSVIETLVARTLRQVESSQSMIRIIGLSATLPNFMDVADFLG-VNRQIGMFYFDQSFRPKPLEQQLLGCRG------------------KAGSRQSKENIDKVAYDKLSEMIQRGYQ-------------------VMVFVHSRKETVKSARNFIKLAESNHEVDLFAPDPIEKDKYSRSLVKNRDKDMKEI------FQFGFGIHHAGMARSDRNLTEKMFKDGAIKVLCCTATLAWGVNLPADCVIIKGTQVYDSKKGGFI 655

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Nematostella
Match: EDO43976 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX65])

HSP 1 Score: 1013.83 bits (2620), Expect = 0.000e+0
Identity = 515/965 (53.37%), Postives = 681/965 (70.57%), Query Frame = 3

Query:  330 ESFSHEVAVPPTIEFEPL-KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKL---GPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRP------GEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            E+ +HEVA P   E+ PL +    P K YPF LD FQK A++C++N +SVL+SAHTSAGKTV+AEYAIA +L  KQRVIYTTPIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS +MREV WV+FDEIHYMRD+ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHVV+T++RP PLQHY++P  GDGL LVVD+KG F E+NF+ AM  +   G +  +   R G        K  SN FKIV++IME   +P+I+FSFSKKECE YA Q++KL+FN+ +E   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HH GLLPILKET+EILFSEGL+K LFATETFA+GLNMPARTV+F++ARK+DG ++R+I++ EYIQMSGRAGRRG DERG VIL++DE M     + +++G  DPLNSAFH+TYNM+LNL+RVE INPE M+E+SF+QFQN A +P   E +K L +  +++E+  EE   +Y+K+ + L+      + +IH+    + FMQPGRL++V+ + EDFGWGAV+N +++  Q  K S A  D  LY++E LL  +  P   K      P+P      GE +V  V    +  +  IS+VRL +P+DLR   +R+ V ++I+++K++F                  + LP+LD I+D+ I D+   KI RKIE  E ++  H        +++     +K     EI    KE+ + R+I+Q++ELK RKRVLRRL Y    DVIE+KGRVACE++  DELL+TE++  GVFN L   Q+ A +SC + EE+S EMP L   L+   R +Q  A+ +A +S E +++++ E Y++ F+PH+MDVV  WA+G +F Q+   T IFEGS+IRC+R LEE+LRQ+  AAK IGNT LE KF E I  IKRDIVFAASLYL
Sbjct:   98 EACTHEVAFPKGFEYTPLVQSAAKPAKEYPFILDPFQKEALRCLENNKSVLISAHTSAGKTVVAEYAIAMSLQKKQRVIYTTPIKALSNQKYRELYEEFQDVGLMTGDVTINPTASALVMTTEILRSMLYRGSEVMREVAWVVFDEIHYMRDKERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWIVHLHKQPCHVVYTDFRPTPLQHYIYPAGGDGLFLVVDEKGDFREENFQKAMGVIRVGGGDPGAQRGRKGGT------KGPSNTFKIVKMIMERNFQPVIIFSFSKKECEAYALQMSKLDFNTAQEKTLVEEVFNNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHSGLLPILKETIEILFSEGLIKALFATETFALGLNMPARTVVFSNARKFDGKDFRFITSGEYIQMSGRAGRRGLDERGIVILIIDEKMGPDVGKGLLKGHADPLNSAFHLTYNMVLNLLRVEEINPEIMLEKSFYQFQNYAAIPAMIEKMKDLESKRDQVEIPNEESITAYYKIRQQLKKLADDMLAFIHQPKYCLPFMQPGRLVRVQNNDEDFGWGAVLNFQKKANQ--KASGAVGD-TLYVLEVLLKCS--PKAIKSADGDIPKPCGPDEKGEMQVVPVL---MHLVKRISSVRLYIPKDLRSLDSRQSVGKSIQEVKKRFP-----------------DGLPLLDPIEDMGIKDDGLKKIVRKIEMLEHRMYTHPLHKDPELDKLYSLCEKKAMVSNEIRAARKELKRARTILQLDELKCRKRVLRRLGYATASDVIEVKGRVACELSSGDELLLTEMIFNGVFNELTTEQSVALLSCFICEERSDEMPKLREELAGPLRQMQESARRIAKVSQEAKMELDVEEYVEKFRPHIMDVVFAWANGSSFSQICKMTDIFEGSVIRCMRRLEELLRQMCQAAKAIGNTELENKFAEGIVKIKRDIVFAASLYL 1031

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Nematostella
Match: EDO38196 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDN7])

HSP 1 Score: 536.954 bits (1382), Expect = 4.871e-175
Identity = 345/966 (35.71%), Postives = 524/966 (54.24%), Query Frame = 3

Query:  384 KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFS------EVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKN---ESNVFKIVRLIMEHKLE-PLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPE----AEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNI---------KRQQPQ-LLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGEAKVAEVTLLKLKTIS-AISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            K++ +    + FE D FQK AI  ++   SV V+AHTSAGKT +AEYAIA A   + R IYT+PIKALSNQK+R+F +  S      ++GLLTGDV + P AS LIMTTEIL+SMLY GS ++R+V WVIFDE+HY+ D ERGVVWEE +++LPD +    LSAT+PN  +FA+WI     +  +V+ T  RPVPL+H+++  N +     L L+VD   +FL   +++A++     +    +  G+   AR+  N   + +V+  +  ++E K + P++ F+FS+++CE  A QL+ LN  +  E + +    +  +  L  +DK LPQV     LL+RGIGVHH G+LPILKE +EILF EGL+K L+ATETFAMG+NMPARTV+F S RK DGS +R +   EY+QM+GRAGRRGKD  GTVI++    + +  D  K++ G P  L S F +TY+M+LNL+RVE +  E M++RSF +F  Q    E    AE+  K L    +   V   E   SY++    L +   +       S      + PGR++ +           ++ +           ++PQ ++   S+      YL   L     RP    ++  R  +   ++++E+T+ ++K    AIS       QD R      K +Q   +         +      +      E +  +D +KD  I D   +    +  S ++ +     +N  NF E   S    E    +  +  K ++  +S+  + E   R  VLR+L Y +  + +ELKGRVACE++   EL++TEL+    F  L  ++  A +SC VF++++   P L   L      + + A+ +A+  +EC L+  ++ Y   F   +++ V  WA G  F ++   T + EG I+RCI+ L   L         IG+  L +K  +A   +KRDIVFA SLY
Sbjct:   13 KKVPDMAHKWDFEPDTFQKQAILRLEAHDSVFVAAHTSAGKTAVAEYAIALAHQHRTRTIYTSPIKALSNQKFRDFKKTLSVDHPGLDIGLLTGDVQIKPEASCLIMTTEILRSMLYNGSDVIRDVEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNTLEFADWIGRTKRKKIYVISTAKRPVPLEHFLYTGNSNKTSNELFLLVDQHSKFLTRGYQAAIDAKKERASKGKDAYGA-KGARTNYNPKADRSVWLSLITMLEKKDKLPVVAFTFSRRKCEENADQLSNLNLTTSVERSRIHVEMQKYLARLKGSDKTLPQVTRMQELLQRGIGVHHSGILPILKEMIEILFQEGLVKLLYATETFAMGVNMPARTVVFDSTRKNDGSSFRDLLPGEYVQMAGRAGRRGKDTTGTVIILCKGDVPEASDLHKMMLGKPTTLVSQFRLTYSMILNLLRVEQLRVEDMMKRSFSEFHLQRDATERRQKAEQLEKELADVRDVECVLCGEDLKSYYQACSELSDLTHRVKAAALSSPHGQKALLPGRIVVLDTVEHKNALAVILQVLVLCEEEASDSEKPQEIVSTQSSAASLQPYLARSLF----RPEG--RSAHRVVQVLGSEISEITVRQMKIDGDAIS-------QDFR------KRMQPRFRNDPPCRSAIAAEQELLRLTEANPEGIETMDPVKDFNIRDLDMVDAITRQRSLQEIMRTFTCINCPNFYEHF-SQVRDEMVLRQNLDHLKFLLSDQSLQLLPEYHQRIEVLRKLRYIDRTNRVELKGRVACEMSN-HELMITELVFHSAFTGLQHTEIVALLSCFVFQQRNCSEPKLTSVLEEGKERILSIAEAIANCQLECGLNTPADDYKGQFYFGLVEAVYEWARGMPFAEITTLTDVQEGVIVRCIQRLYSPL--------IIGDPTLYQKMEKASTAVKRDIVFATSLY 948

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Nematostella
Match: EDO46714 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPC5])

HSP 1 Score: 114.39 bits (285), Expect = 1.442e-25
Identity = 109/420 (25.95%), Postives = 182/420 (43.33%), Query Frame = 3

Query:  459 DNRQSVLVSAHTSAGKTVIAEYAIAKALSDK---QRVIYTTPIKALSNQKYREFSEEFSE-----VGLLTGDVTLSP----NASVLIMTTEILQ--SMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLL-------PDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYV--FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYV---DEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWIS--ANEYIQMSGRAGRRGKDERGTVILMVDE 1634
            ++  +VL+ A T +GKT+IAE AI + L DK    + +Y  P+KAL  ++  ++   F       V  LTGDVT        A +++ T E     S  ++  S +++V  +I DEIH + D ERG V E  +            ++R   LS  + NAR  A+W+      + +      RPVPL+ ++  FP                                       G     R        F+ +R+      +P +VF  S+++  + A  L       D+   ++   +E  +  +  + D++ +L        +L  GIG+HH GL    +  VE LF    ++ L AT T A G+N PA  V+      +DG + R++     + +QM GRAGR   D++G  +++V +
Sbjct: 1345 NSDHNVLLGAPTGSGKTIIAELAIFR-LFDKYPGAKAVYIAPLKALVRERMDDWKVRFGRKLGKRVIELTGDVTPDSRSISQADLIVTTPEKWDGISRSWQTRSYVKQVNLLIIDEIHLLGD-ERGPVLEVIVSRTNFISSHTDKKVRVVGLSTALANARDLADWLGIGSAGMFNFR-PSVRPVPLEVHITGFP---------------------------------------GKHYCPRMATMNKPTFEAIRI--HSPTKPTLVFVSSRRQTRLTALDLIAFLAAQDDPKQWLHMPEEEMEQVLHAVRDSNLKL--------VLSFGIGLHHAGLHERDRSVVEELFVNQKIQVLIATSTLAWGVNFPAHLVVIKGTEYFDGKKCRYVDFPITDVLQMMGRAGRPQYDDQGKAVILVHD 1712

HSP 2 Score: 100.138 bits (248), Expect = 3.241e-21
Identity = 107/429 (24.94%), Postives = 184/429 (42.89%), Query Frame = 3

Query:  459 DNRQSVLVSAHTSAGKTVIAEYAIAKALS----------DKQRVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLSP----NASVLIMTTEILQSMLYRGS---SIMREVGWVIFDEIHYMRDRERGVVWE-------ESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSA--MNKLGPNSDSTS-ERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAY---VDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISAN--EYIQMSGRAGRRGKDE--RGTVILMVD 1631
            +  +++L+ A T AGKT IA   I + +           DK +++Y  P+KAL+ +  R FS+  + +G+    LTGD+ L+        +L+ T E    +  + +   ++ + V  +I DE+H + D +RG V E         ++     IR   LSAT+PN    A ++     +      + +RPVPL        G               + F+ A  M+K+     + + E+   +MV    +N +     VR  M  +              E+ + Q   + F +++   Y   + +V ++  + L D             L   G G HH G+L   +  VE  F++GL+K L  T T A G+N+PA  V+      YD  +  ++     + +Q+ GRAGR   D+   GT+I   D
Sbjct:  495 NTNENLLICAPTGAGKTNIAMMTIVREIKQNIEQGVIKKDKFKIVYVAPMKALAAEMVRNFSKRLAGLGISVRELTGDMQLTKMEILKTQMLVTTPEKWDVVTRKSTGDVALAQLVKLLIIDEVHLLHD-DRGSVIECLVARTLRQVLSSQSMIRIVGLSATLPNYLDVAHFLRVDPYKGLFAFDSRFRPVPLGQTFIGVKG--------------LNPFQQAHEMDKICYEKVTENVEKGYQVMVFVHARNAT-----VRTAMTLR--------------EMASNQGDSMLFRAEQAPDYGSALKQVMRSRNKQLRD-------------LFPDGFGTHHAGMLRTDRTMVEQYFAKGLIKVLVCTATLAWGVNLPAHAVIIKGTEVYDAKKGSFVDLGILDVLQIFGRAGRPQFDKFGEGTIITAHD 876

[Close]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Nematostella
Match: EDO49146 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH22])

HSP 1 Score: 104.375 bits (259), Expect = 1.809e-22
Identity = 104/427 (24.36%), Postives = 186/427 (43.56%), Query Frame = 3

Query:  453 CIDNRQSVLVSAHTSAGKTVIAEYAIAKAL-----------SDKQRVIYTTPIKALSNQKYREFSEEFSEVGL----LTGDVTLSP---NASVLIMTTEILQSMLYRGS---SIMREVGWVIFDEIHYMRDRERGVVWE-------ESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSD------EETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWI--SANEYIQMSGRAGRRGKDERGTVILM 1625
             +++ +++L+ A T AGKT +A   I + +           +++ ++IY  P+++L  +    FS+  S  GL    LTGD  L+    + + +I+ T     ++ R S   +  + V  +I DEIH + D +RG V E         I    + +R   LSAT+PN    A ++     +        +RPVPL+                   +F+    K  + ++   ++   E+    +V  + KN+                 ++VF  S+KE    A  +  +    D       E +   EV ++  E + + + +         LL  G  +HH G+  + +  VE LF++  ++ L +T T A G+N+PA TV+    + Y   + RW+   A + +QM GRAGR   D +G  IL+
Sbjct:  492 ALNSDENLLLCAPTGAGKTNVALLTILREIGKHINLDGTINTEEFKIIYVAPMRSLVQEMVLNFSKRLSTYGLTVSELTGDHNLTKEQIHGTQIIVCTPEKWDIITRKSGERTFTQLVRLIIIDEIHLLHD-DRGPVLESLVARTIRQIETTQELVRLVGLSATLPNYEDVATFMRVNPAKGLFFFDNSFRPVPLEQ------------------QFIGITEKKPIKRMQATNEVVYEK----VVEHAGKNQ-----------------VLVFVHSRKETAKTAKAVRDMCLERDSLGLFLREDSASTEVLRSEAEQVKNGELK--------DLLPYGFAIHHAGMSRVDRTLVEDLFADRHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWVELGALDILQMLGRAGRPQYDTKGEGILI 870

HSP 2 Score: 85.8853 bits (211), Expect = 7.219e-17
Identity = 102/455 (22.42%), Postives = 188/455 (41.32%), Query Frame = 3

Query:  459 DNRQSVLVSAHTSAGKTVIAEYAIAKAL--SDKQRVIYTTPIKALSNQKYREFSEEFS-----EVGLLTG----DVTLSPNASVLIMTTEILQ--SMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVL---------LPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHK-LEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSD---------ADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWIS--ANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTP--DPLNSAFHITYN 1715
            D+ ++V + A T +GKT+ AE+A+ + L  S + R +Y TPI+AL+ Q Y ++  +F       V +LTG    D+ L    +V++ T E     S  ++    ++ V   I DE H +   + G V E  I+          L   IR   LS+++ NA+  A+W+      L +      RPVPL+ ++                              G N   TS R    ++A ++        + + IM+H   +P +VF  S+++ ++ A  +   +   +E   +        + C  D          DK L + +T       GI   H GL     + V  LF+ G ++ +  + T  + +N+ A  V+    + Y+G  + +      + + M G A R   D+ G  +++   +  +   + + +  P    L+   H  +N
Sbjct: 1341 DSSENVFIGAPTGSGKTICAEFAVLRFLQQSPEGRCVYVTPIQALAEQVYADWQNKFGLQLGKNVVMLTGETSADLKLLAKGNVVVSTPEKWDVLSRRWKQRKNVQNVSLFIMDEAHLI-GGDTGPVME--IICSRMRYISSQLERTIRIVALSSSLANAKDVAQWLGVPSTGLFN-FHPNVRPVPLELHI-----------------------------QGFNITHTSSR----LIAMTK-------PVYQAIMKHSPKKPAVVFVPSRRQTKLLALDILTFSGADNEPQRF--------LHCTEDDLNPFVSRLTDKTLKETVTY------GIAFLHEGLSDAEVKIVNQLFTSGAIQVVVVSRTLCLSVNLSAHLVVVMDTQFYEGKTHSYADYPVTDVLHMIGHASRPLLDDAGKAVILCQASKKEFFKKFLYEPLPIESHLDHTLHDHFN 1737

[Close]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Nematostella
Match: EDO44748 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUT3])

HSP 1 Score: 90.8929 bits (224), Expect = 1.267e-18
Identity = 108/436 (24.77%), Postives = 189/436 (43.35%), Query Frame = 3

Query:  423 LDNFQKAAIK--CIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQR-VIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNA----------SVLIMTTEILQSMLYRGSSI----MREVGWVIFDEIHYMRDRE-RGVVWEESI---VLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYV--------FPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIV-RLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEET-AYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDET 1637
            L  +Q A +K   I  +++++ S  TS GKT++AE  + K L    + V+   P  ++  +K +  ++   E+G +  +   S             ++ I T E   S++   S I    M ++G ++ DE+H + +   RG   E  +   +   + I+   +SAT+ N     +++      +  V   ++RPV LQ YV         PC+            +   D     + ++G + D            R  K+  ++  +V  +I +H     ++F  +KK CE  A  +  + F   E T   + E  +        A+   P +  S+P    GI  HH GL    ++ +E  +S+G+L  L  T T A G+N+PA+ V+  +   Y G     I  ++Y QM GRAGR G D  G  IL++  T
Sbjct:   21 LYEWQDACLKLPAIQEKRNLIYSLPTSGGKTLVAEILMMKELLVHHKDVVLVLPFVSIVQEKVKTITQFAVELGFVVEEYAGSKGKFPPRKRRTKRALYIATIEKANSLV--NSLIEEKRMDDLGLIVVDELHMLGEGGGRGATLEMCLAKTLFSTNHIQIVGMSATLSNIGDLQKFL------MAEVYSNDFRPVELQEYVKVDNIVYKVPCSSS----------KSEADEIYVQVRRIGHSPDQ-----------RHIKDPDHLVPLVLEVIPQHSC---LIFCATKKNCENVAKLM--VEFLPREMTQVKIGERMELLQALHHQANGLCPVLKKSVPY---GIAYHHSGLTMDERKLIEDAYSQGVLCALTCTSTLAAGVNLPAKRVILRAP--YIGRNI--IRKSQYKQMIGRAGRAGIDSTGESILIIKTT 415

[Close]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Medaka
Match: mtrex (Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:100304468])

HSP 1 Score: 1049.27 bits (2712), Expect = 0.000e+0
Identity = 536/977 (54.86%), Postives = 693/977 (70.93%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKL----------GPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPR-PGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            +IK+ +V   E  SHEVA+P   EF+PLK+ V    K YPF LD FQ+ AI CIDN QSVLVSAHTSAGKTV AEYAIA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS IMREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHVV+T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L          G   D    + G+       K  S+VFKIV++IME   +P+I+FSFSKKECE YA Q+AKL+FN+D+E   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGLLK LFATETFAMG+NMPARTVLFTSARK+DG  +R+I++ EYIQMSGRAGRRG D+RG VI MVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   +P   E +K L   Y  +E+  EE   +YFK+ + L     +  ++IHK    + F+QPGRL+KVK+D  DFGWG VVN  ++        ++T  + LY+VE LL  +     N  T    P  PGE    +V  + L  +++IS+VRL +P+DLRP  NR+ ++++I++++++F                  + +P+LD I D+ I D    K+ +K+E++E ++  H   +  N E +     +K     E+   ++E+ K R+++QM+ELK RKRVLRRL + +  DVIE+KGRVACEI+  DELL+TE++  G+FN+L+  Q  A +SC VF+E +SE+P L   L+   R +Q  AK +A +S + +L+V+ E+Y+  FK H+MDVV  WA+G +F Q+   T +FEGSIIRC+R LEEVLRQ+ +AAK IGNT LE KF E I  IKRDIVFAASLYL
Sbjct:   88 QIKVEQVDTVEGCSHEVALPADYEFKPLKQRVGKAAKEYPFVLDPFQREAILCIDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLITGDVTINPTASCLVMTTEILRSMLYRGSEIMREVAWVIFDEIHYMRDAERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVVYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDVGDSGGSGGGKWDPRGRKGGT-------KGPSSVFKIVKMIMERNFQPVIIFSFSKKECEAYALQVAKLDFNTDDEKRLVEEVFNNAVDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKALFATETFAMGINMPARTVLFTSARKFDGKSHRFITSGEYIQMSGRAGRRGMDDRGIVIFMVDEKMSPAVGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRALPGVVEKIKKLEEQYHTIEIPNEESVVTYFKIRQQLAKLSKEIQEFIHKPKYCLPFLQPGRLVKVKKDDADFGWGVVVNFCKKT----NVKASTDSDPLYVVEVLLHCSKESMKNAATEAAKPAPPGETGEMQVVPVMLHLLTSISSVRLYIPKDLRPFDNRQLMLKSIQEVQKRFP-----------------DGVPLLDPIDDMGIKDPGLKKVIQKVEAFEHRMYTHPLHSDPNLESVYSLCEKKALIATEVRTAKRELKKARTVLQMDELKCRKRVLRRLGFASPSDVIEMKGRVACEISSGDELLLTEMMFNGLFNDLSVEQATALLSCFVFQENASEIPKLTEQLAAPLRQMQECAKRIAKVSADAKLEVDEETYLSQFKSHLMDVVFAWANGSSFSQICKMTDVFEGSIIRCMRRLEEVLRQMCSAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 1036

[Close]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Medaka
Match: mtrex (Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:100304468])

HSP 1 Score: 976.852 bits (2524), Expect = 0.000e+0
Identity = 511/977 (52.30%), Postives = 666/977 (68.17%), Query Frame = 3

Query:  300 RIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKL----------GPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPR-PGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            +IK+ +V   E  SHEVA+P   EF+PLK+ V    K YPF LD FQ+ AI CIDN QSVLVSAHTSAGKTV AEYAIA AL +KQRVI+T+PIKALSNQKYRE  EEF +VGL+TGDVT++P AS L+MTTEIL+SMLYRGS IMREV WVIFDEIHYMRD ERGVVWEE+I+LLPD +   FLSATIPNARQFAEWI  LH Q CHVV+T+YRP PLQHY+FP  GDGL LVVD+ G F EDNF +AM  L          G   D    + G+       K  S+VFKIV++IME   +P+I+FSFSKKECE YA Q+AKL+FN+D+E   V+EVF NA++CLSD DK+LPQV   LPLL+RGIG+HHGGLLPILKET+EILFSEGLLK                     TS +    +    I++ EYIQMSGRAGRRG D+RG VI MVDE MS    +++++G+ DPLNSAFH+TYNM+LNL+RVE INPEYM+E+SF+QFQ+   +P   E +K L   Y  +E+  EE   +YFK+ + L     +  ++IHK    + F+QPGRL+KVK+D  DFGWG VVN  ++        ++T  + LY+VE LL  +     N  T    P  PGE    +V  + L  +++IS+VRL +P+DLRP  NR+ ++++I++++++F                  + +P+LD I D+ I D    K+ +K+E++E ++  H   +  N E +     +K     E+   ++E+ K R+++QM+ELK RKRVLRRL + +  DVIE+KGRVACEI+  DELL+TE++  G+FN+L+  Q  A +SC VF+E +SE+P L   L+   R +Q  AK +A +S + +L+V+ E+Y+  FK H+MDVV  WA+G +F Q+   T +FEGSIIRC+R LEEVLRQ+ +AAK IGNT LE KF E I  IKRDIVFAASLYL
Sbjct:   88 QIKVEQVDTVEGCSHEVALPADYEFKPLKQRVGKAAKEYPFVLDPFQREAILCIDNNQSVLVSAHTSAGKTVCAEYAIALALREKQRVIFTSPIKALSNQKYREMYEEFQDVGLITGDVTINPTASCLVMTTEILRSMLYRGSEIMREVAWVIFDEIHYMRDAERGVVWEETIILLPDNVHYVFLSATIPNARQFAEWICHLHKQPCHVVYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDVGDSGGSGGGKWDPRGRKGGT-------KGPSSVFKIVKMIMERNFQPVIIFSFSKKECEAYALQVAKLDFNTDDEKRLVEEVFNNAVDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLLKV--------------------TSVQFLQIATPLIITSGEYIQMSGRAGRRGMDDRGIVIFMVDEKMSPAVGKQLLKGSADPLNSAFHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRALPGVVEKIKKLEEQYHTIEIPNEESVVTYFKIRQQLAKLSKEIQEFIHKPKYCLPFLQPGRLVKVKKDDADFGWGVVVNFCKKT----NVKASTDSDPLYVVEVLLHCSKESMKNAATEAAKPAPPGETGEMQVVPVMLHLLTSISSVRLYIPKDLRPFDNRQLMLKSIQEVQKRFP-----------------DGVPLLDPIDDMGIKDPGLKKVIQKVEAFEHRMYTHPLHSDPNLESVYSLCEKKALIATEVRTAKRELKKARTVLQMDELKCRKRVLRRLGFASPSDVIEMKGRVACEISSGDELLLTEMMFNGLFNDLSVEQATALLSCFVFQENASEIPKLTEQLAAPLRQMQECAKRIAKVSADAKLEVDEETYLSQFKSHLMDVVFAWANGSSFSQICKMTDVFEGSIIRCMRRLEEVLRQMCSAAKAIGNTELENKFAEGITKIKRDIVFAASLYL 1016

[Close]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Medaka
Match: skiv2l (Ski2 like RNA helicase [Source:NCBI gene;Acc:101154960])

HSP 1 Score: 454.907 bits (1169), Expect = 6.767e-141
Identity = 222/480 (46.25%), Postives = 317/480 (66.04%), Query Frame = 3

Query:  384 KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVAR---SQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQA 1799
            K I NP   +PFELD FQK AI  ++   SV V+AHTSAGKTV+AEYAIA +     R IYT+PIKALSNQK+R+F   F +VGLLTGDV LSP ++ LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LPD +    LSAT+PNA +F+EWI  +  +  +V+ T  RPVPL+H+++  N       + L+VD  G FL   + +A++     S   ++  G+   ++   + ++ S    ++  + + +  P++ F+FS+  C+  A  L  ++  +  E A +   F+ ++  L   D++LPQ+L    LL+RG+ VHH G+LPILKE +E+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DG+ +R +   EYIQM+GRAGRRG D  GTVI++    + ++ D   ++ G P  L S F +TY M+LNL+RVE +    M++RSF +    A
Sbjct:  306 KRIPNPAFKWPFELDVFQKQAILRLEAHDSVFVAAHTSAGKTVVAEYAIALSQKHMTRTIYTSPIKALSNQKFRDFKTTFKDVGLLTGDVQLSPESACLIMTTEILRSMLYNGSEVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFSEWIGRIKKKHIYVISTMKRPVPLEHHLYTGNSTKTQKEMFLLVDAAGNFLTKGYYAAVDAKKERSSKHAQTFGAKNTSQNTTASQDRSVWLALLHFLSQRQQTPVVAFTFSRARCDDNARSLESMDLTTSVEKAEIHSFFQKSLSRLRGGDRQLPQILLMRDLLKRGVAVHHSGILPILKEVIEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSIRKHDGTGFRNLLPGEYIQMAGRAGRRGLDATGTVIILCKAGVHEMADLHAMMMGKPTILQSQFRLTYTMILNLLRVEALRVTDMMKRSFSESHRNA 785

HSP 2 Score: 87.0409 bits (214), Expect = 7.357e-17
Identity = 66/198 (33.33%), Postives = 98/198 (49.49%), Query Frame = 3

Query: 2598 SIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            S+  + E   R +VL+ L Y +    ++LKGRVAC+I+ + ELL+TELL + V + L P ++AA +SCLVF +K+   P L   L   F     E  +L DI                                            EG+++RCI+ L+EVL+++  AA+ +G++ L  K   A   I+RDIVF ASLY
Sbjct: 1048 SLTLLPEYHQRIKVLQSLQYIDSGGAVQLKGRVACQIS-SHELLLTELLFENVMSPLAPEESAALLSCLVFTQKTQVEPHLTSTLKEPF----AEIALLTDIQ-------------------------------------------EGTVVRCIQRLDEVLKEVRQAARIVGDSVLGSKMERASLAIRRDIVFTASLY 1197

[Close]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Medaka
Match: skiv2l (Ski2 like RNA helicase [Source:NCBI gene;Acc:101154960])

HSP 1 Score: 454.136 bits (1167), Expect = 2.906e-140
Identity = 222/480 (46.25%), Postives = 317/480 (66.04%), Query Frame = 3

Query:  384 KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVAR---SQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQA 1799
            K I NP   +PFELD FQK AI  ++   SV V+AHTSAGKTV+AEYAIA +     R IYT+PIKALSNQK+R+F   F +VGLLTGDV LSP ++ LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LPD +    LSAT+PNA +F+EWI  +  +  +V+ T  RPVPL+H+++  N       + L+VD  G FL   + +A++     S   ++  G+   ++   + ++ S    ++  + + +  P++ F+FS+  C+  A  L  ++  +  E A +   F+ ++  L   D++LPQ+L    LL+RG+ VHH G+LPILKE +E+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DG+ +R +   EYIQM+GRAGRRG D  GTVI++    + ++ D   ++ G P  L S F +TY M+LNL+RVE +    M++RSF +    A
Sbjct:  306 KRIPNPAFKWPFELDVFQKQAILRLEAHDSVFVAAHTSAGKTVVAEYAIALSQKHMTRTIYTSPIKALSNQKFRDFKTTFKDVGLLTGDVQLSPESACLIMTTEILRSMLYNGSEVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFSEWIGRIKKKHIYVISTMKRPVPLEHHLYTGNSTKTQKEMFLLVDAAGNFLTKGYYAAVDAKKERSSKHAQTFGAKNTSQNTTASQDRSVWLALLHFLSQRQQTPVVAFTFSRARCDDNARSLESMDLTTSVEKAEIHSFFQKSLSRLRGGDRQLPQILLMRDLLKRGVAVHHSGILPILKEVIEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSIRKHDGTGFRNLLPGEYIQMAGRAGRRGLDATGTVIILCKAGVHEMADLHAMMMGKPTILQSQFRLTYTMILNLLRVEALRVTDMMKRSFSESHRNA 785

HSP 2 Score: 127.872 bits (320), Expect = 2.125e-29
Identity = 75/198 (37.88%), Postives = 121/198 (61.11%), Query Frame = 3

Query: 2598 SIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            S+  + E   R +VL+ L Y +    ++LKGRVAC+I+ + ELL+TELL + V + L P ++AA +SCLVF +K+   P L   L  +   + + A+ + ++  EC +   +E ++  FK  + +VV  WA G  F ++   T I EG+++RCI+ L+EVL+++  AA+ +G++ L  K   A   I+RDIVF ASLY
Sbjct: 1048 SLTLLPEYHQRIKVLQSLQYIDSGGAVQLKGRVACQIS-SHELLLTELLFENVMSPLAPEESAALLSCLVFTQKTQVEPHLTSTLKESIERVLSVARRIGELQRECGIPQTAEEFVGQFKFGLTEVVYCWARGMPFAEIALLTDIQEGTVVRCIQRLDEVLKEVRQAARIVGDSVLGSKMERASLAIRRDIVFTASLY 1244

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Medaka
Match: skiv2l (Ski2 like RNA helicase [Source:NCBI gene;Acc:101154960])

HSP 1 Score: 447.203 bits (1149), Expect = 5.779e-138
Identity = 221/478 (46.23%), Postives = 311/478 (65.06%), Query Frame = 3

Query:  384 KEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDG----LLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVF-KIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDI-DARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQA 1799
            K I NP   +PFELD FQK AI  ++   SV V+AHTSAGKTV+AEYAIA +     R IYT+PIKALSNQK+R+F   F +VGLLTGDV LSP ++ LIMTTEIL+SMLY GS ++R++ WVIFDE+HY+ D ERGVVWEE +++LPD +    LSAT+PNA +F+EWI  +  +  +V+ T  RPVPL+H+++  N       + L+VD  G FL   +   +                +   R Q+ + +V+  ++  + + +  P++ F+FS+  C+  A  L  ++  +  E A +   F+ ++  L   D++LPQ+L    LL+RG+ VHH G+LPILKE +E+LFS GL+K LFATETFAMG+NMPARTV+F S RK+DG+ +R +   EYIQM+GRAGRRG D  GTVI++    + ++ D   ++ G P  L S F +TY M+LNL+RVE +    M++RSF +    A
Sbjct:  291 KRIPNPAFKWPFELDVFQKQAILRLEAHDSVFVAAHTSAGKTVVAEYAIALSQKHMTRTIYTSPIKALSNQKFRDFKTTFKDVGLLTGDVQLSPESACLIMTTEILRSMLYNGSEVIRDLEWVIFDEVHYINDAERGVVWEEVLIMLPDHVSIILLSATVPNALEFSEWIGRIKKKHIYVISTMKRPVPLEHHLYTGNSTKTQKEMFLLVDAAGNFLTKGYGFTV----------------LCSRRCQEGDRSVWLALLHFLSQRQQTPVVAFTFSRARCDDNARSLESMDLTTSVEKAEIHSFFQKSLSRLRGGDRQLPQILLMRDLLKRGVAVHHSGILPILKEVIEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSIRKHDGTGFRNLLPGEYIQMAGRAGRRGLDATGTVIILCKAGVHEMADLHAMMMGKPTILQSQFRLTYTMILNLLRVEALRVTDMMKRSFSESHRNA 752

HSP 2 Score: 127.872 bits (320), Expect = 1.975e-29
Identity = 75/198 (37.88%), Postives = 121/198 (61.11%), Query Frame = 3

Query: 2598 SIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLY 3191
            S+  + E   R +VL+ L Y +    ++LKGRVAC+I+ + ELL+TELL + V + L P ++AA +SCLVF +K+   P L   L  +   + + A+ + ++  EC +   +E ++  FK  + +VV  WA G  F ++   T I EG+++RCI+ L+EVL+++  AA+ +G++ L  K   A   I+RDIVF ASLY
Sbjct: 1015 SLTLLPEYHQRIKVLQSLQYIDSGGAVQLKGRVACQIS-SHELLLTELLFENVMSPLAPEESAALLSCLVFTQKTQVEPHLTSTLKESIERVLSVARRIGELQRECGIPQTAEEFVGQFKFGLTEVVYCWARGMPFAEIALLTDIQEGTVVRCIQRLDEVLKEVRQAARIVGDSVLGSKMERASLAIRRDIVFTASLY 1211

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Planmine SMEST
Match: SMESG000004673.1 (SMESG000004673.1)

HSP 1 Score: 1904.41 bits (4932), Expect = 0.000e+0
Identity = 997/1027 (97.08%), Postives = 1000/1027 (97.37%), Query Frame = 3

Query:   66 CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEA 3146
            CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIAAYEEMEVEQEELAASYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAA     KK P                   ++ +AISAVRLVMPQDLRPTGNREKVIQNIEKIKEKFFEMKSEMMSSNKSPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFREKEKKRLEIENLEKEIIKKRSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLE 
Sbjct:    5 CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIAAYEEMEVEQEELAASYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAADRTTIKKLP-------------------QSSAAISAVRLVMPQDLRPTGNREKVIQNIEKIKEKFFEMKSEMMSSNKSPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFREKEKKRLEIENLEKEIIKKRSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEG 1012

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Planmine SMEST
Match: SMESG000004886.1 (SMESG000004886.1)

HSP 1 Score: 1844.71 bits (4777), Expect = 0.000e+0
Identity = 961/1028 (93.48%), Postives = 964/1028 (93.77%), Query Frame = 3

Query:   66 CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFE-EILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEA 3146
            CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIAAYEEMEVEQEELAASYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAA     KK P       E +V E         +AISAVRLVMPQDLRPTGNREKVIQNIEKIKEKFFEMKSEMMSSNKSPSVRNEDLPILDAIKDVKIDDESFLKIKRK             L I N E EI+K                      RSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLE 
Sbjct:    5 CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIAAYEEMEVEQEELAASYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAADRTTIKKLPQ------ELRVPERR-------NAISAVRLVMPQDLRPTGNREKVIQNIEKIKEKFFEMKSEMMSSNKSPSVRNEDLPILDAIKDVKIDDESFLKIKRK------------RLEIENLEKEIIKK---------------------RSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEG 986

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BLAST of Superkiller viralicidic activity 2-like 2 vs. Planmine SMEST
Match: SMESG000004886.1 (SMESG000004886.1)

HSP 1 Score: 1837.77 bits (4759), Expect = 0.000e+0
Identity = 958/1028 (93.19%), Postives = 961/1028 (93.48%), Query Frame = 3

Query:   66 CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFE-EILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEA 3146
            CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIAAYEEMEVEQEELAASYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAA     KK P       E +V E            +AVRLVMPQDLRPTGNREKVIQNIEKIKEKFFEMKSEMMSSNKSPSVRNEDLPILDAIKDVKIDDESFLKIKRK             L I N E EI+K                      RSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLE 
Sbjct:    5 CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIAAYEEMEVEQEELAASYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAADRTTIKKLPQ------ELRVPERR----------NAVRLVMPQDLRPTGNREKVIQNIEKIKEKFFEMKSEMMSSNKSPSVRNEDLPILDAIKDVKIDDESFLKIKRK------------RLEIENLEKEIIKK---------------------RSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEG 983

[Close]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Planmine SMEST
Match: SMESG000004886.1 (SMESG000004886.1)

HSP 1 Score: 1717.21 bits (4446), Expect = 0.000e+0
Identity = 912/1043 (87.44%), Postives = 916/1043 (87.82%), Query Frame = 3

Query:   66 CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEV---------------AVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFE-EILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEA 3146
            CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEV               AVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQ                                             +EETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIAAYEEMEVEQEELAASYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAA     KK P       E +V E            +AVRLVMPQDLRPTGNREKVIQNIEKIKEKFFEMKSEMMSSNKSPSVRNEDLPILDAIKDVKIDDESFLKIKRK             L I N E EI+K                      RSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLE 
Sbjct:    5 CTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESEKLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVISIIFNILKLVNLKVAVPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQ---------------------------------------------NEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIAAYEEMEVEQEELAASYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAADRTTIKKLPQ------ELRVPERR----------NAVRLVMPQDLRPTGNREKVIQNIEKIKEKFFEMKSEMMSSNKSPSVRNEDLPILDAIKDVKIDDESFLKIKRK------------RLEIENLEKEIIKK---------------------RSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEG 953

[Close]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Planmine SMEST
Match: SMESG000063270.1 (SMESG000063270.1)

HSP 1 Score: 838.18 bits (2164), Expect = 0.000e+0
Identity = 469/1030 (45.53%), Postives = 666/1030 (64.66%), Query Frame = 3

Query:  156 QKRLEDFIQPFIDESEKLETNE-KIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVAVPPTIEFEPLKEIVN-PLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAGKTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDVTLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVWEESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPLQHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMVARSQKN-ESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSDEETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILKETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISANEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFHITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVP-------EAEESLKALIXXXXXXXXXXXXXXXSYFKLDEALQNAYFKEM-DYIHKSSKLINFMQPGRLIKVKRDSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKKTPTRAPRPGEAKVAEVTL--LKLKTISAISAVRLVMPQDLRPTGNREKVIQXXXXXXXXXXXXXXXXXXXXXXPSVRNEDLPILDAIKDVKIDDESFLKIKRKIESYEKKLNNHEFLNISNFEEILKSFXXXXXXXXXXXXXXXXXXXXXSIIQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKGVFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADISVECRLDV----NSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIRCIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL 3194
            +++L+DF+  ++D++  +E  + KI  +   N       I DI         + K    ++  HEV  P  I ++PLK+  + P K + F LD+FQ  AI+CI+N Q+VLVSAHTSAGKTV A Y IA  + +K+RVIYTTPIKALSNQKYREF EEF +VGLLTGDVT+  NASVLIMTTEIL+ MLYR SSI++EVGWVIFDEIHYMRD+ RGVVWEESI+LLP  +R  FLSATIPNARQFA+WI+ LH Q C+V++T+YRP PLQHY++P   D +  VV++KG FL++ F  AM  L    DS+     +I      K  ES+   +++ + + K +P+IVFSFSKK CE+YA  L+KL++ +  E   ++ +F NA   L + D+ LPQ+   L L+RRGIG+HHGGL+P+LKE VEILF EGL+KCLFATETF+MGLNMPA+TV+FTSA K+DG+  R I++ EYIQMSGRAGRRG D  G VILM+D T+ + DA+++I+G  +PLNS+FH+TYNM+LNLMRVE I+PEY++E SFFQFQ  A +P       E E+ L+ +      +  ++     S+++L+++L NA  +EM   I K      F+ PGRL+ +K +  DFGW  +V+  R      K+ S        LV+C++ VA      K+     P P      +  L  ++LK I  +S+V +         G  ++++ +++K  E   E  ++  S       R   + ++D  KD+K   +   +  +KI+  + K+ NH   N     E++  + ++ +     + L  EI KK S+I+M+ELKSRKR+LRR  +C D DVI  KGR+ACEI+  DE+++TELLL G F+NL   Q  AF+SC VFEE  +E+      L  +   ++  A+ ++ +S ECRL+V    + ++Y+++FK  ++++V  WA G TF++L   T I+EGSIIRCIR L+E+L QL  +++ IGN  LE+KF EA +LIKR I+F++SLYL
Sbjct:   26 KRKLDDFLVEYVDKASDVEEKKTKIDVSDFKNP------INDI---------LLKTIPTQNCIHEVVYPKNIVYKPLKKRNSIPAKEFSFTLDSFQNQAIQCIENNQTVLVSAHTSAGKTVCASYTIASCIKEKRRVIYTTPIKALSNQKYREFKEEFEDVGLLTGDVTIDSNASVLIMTTEILRLMLYRNSSIIKEVGWVIFDEIHYMRDKSRGVVWEESIILLPPAMRMVFLSATIPNARQFAQWIAHLHKQPCNVIYTDYRPTPLQHYIYPNGADRIYQVVNEKGEFLDEYFNEAMAVLRKAGDSSKNDMDNIGKRGGVKAIESHCETLIKKVFDLKKDPVIVFSFSKKSCEVYAKMLSKLDYTTKPEKEKIELIFLNARNTLPEIDRTLPQIDAMLNLVRRGIGIHHGGLMPVLKEIVEILFGEGLIKCLFATETFSMGLNMPAKTVIFTSALKFDGANVRMITSGEYIQMSGRAGRRGLDTNGNVILMLDRTIKNEDAKQVIKGETEPLNSSFHLTYNMILNLMRVETISPEYLMENSFFQFQTYAELPNLITRLREKEKQLEEI-----PLSNQEYLSIGSHYRLEKSL-NAIREEMWSSIRKEHTYRPFLVPGRLVHIKYNEHDFGWCILVSKLRSG----KFKS-------LLVDCVIPVAHESLFAKELSMAIPPPKHETRPDGNLFEIELKHIFELSSVVI---------GCTDQLLHSLKKNDEARKEFLNKRNSII----ARYNTIFLIDLKKDLKCKPDQIDEYDQKIQELQTKIENHPMFNHDKSLEMINLYHKRLEYEGIADKLRVEINKKVSLIKMDELKSRKRILRRFKFCTDTDVITTKGRIACEISTGDEIMLTELLLDGEFSNLTGQQLVAFLSCFVFEEFVNEIIEPQNDLDKSLEKMKELARHISRVSKECRLEVYPATDEKAYVENFKLGLIEIVRAWAKGSTFIKLCENTNIYEGSIIRCIRRLDELLGQLYESSRVIGNIQLEKKFGEASQLIKRGIIFSSSLYL 1010

The following BLAST results are available for this feature:

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Human
BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Celegans
BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Fly
BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Zebrafish
BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Xenopus
BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Mouse
BLAST of Superkiller viralicidic activity 2-like 2 vs. UniProt/SwissProt
BLAST of Superkiller viralicidic activity 2-like 2 vs. TrEMBL
BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Cavefish
BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Sea Lamprey
BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Yeast
BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Nematostella
BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Medaka
BLAST of Superkiller viralicidic activity 2-like 2 vs. Planmine SMEST

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MTREX	0.000e+0	55.27	Mtr4 exosome RNA helicase [Source:HGNC Symbol;Acc:...	[more]
SKIV2L	1.634e-173	35.30	Ski2 like RNA helicase [Source:HGNC Symbol;Acc:HGN...	[more]
SKIV2L	1.634e-173	35.30	Ski2 like RNA helicase [Source:HGNC Symbol;Acc:HGN...	[more]
SKIV2L	1.634e-173	35.30	Ski2 like RNA helicase [Source:HGNC Symbol;Acc:HGN...	[more]
SKIV2L	1.634e-173	35.30	Ski2 like RNA helicase [Source:HGNC Symbol;Acc:HGN...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mtr-4	0.000e+0	48.41	mRNA transport homolog 4 [Source:UniProtKB/Swiss-...	[more]
skih-2	7.794e-130	43.85	SKI (Yeast SuperKIller) Helicase homolog [Source:...	[more]
snrp-200	1.688e-27	27.90	Putative U5 small nuclear ribonucleoprotein 200 kD...	[more]
Y54E2A.4	8.850e-25	24.10	pep chromosome:WBcel235:II:14754622:14778149:1 gen...	[more]
Y54E2A.4	9.914e-25	24.10	pep chromosome:WBcel235:II:14768462:14778149:1 gen...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mtr4	0.000e+0	53.85	gene:FBgn0001986 transcript:FBtr0080760	[more]
tst	1.517e-131	44.47	gene:FBgn0039117 transcript:FBtr0334895	[more]
tst	1.517e-131	44.47	gene:FBgn0039117 transcript:FBtr0084462	[more]
obe	2.162e-25	28.07	gene:FBgn0038344 transcript:FBtr0083147	[more]
l(3)72Ab	8.115e-24	26.93	gene:FBgn0263599 transcript:FBtr0075527	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mtrex	0.000e+0	54.54	Mtr4 exosome RNA helicase [Source:ZFIN;Acc:ZDB-GEN...	[more]
skiv2l	2.747e-138	46.84	SKI2 homolog, superkiller viralicidic activity 2-l...	[more]
skiv2l	1.659e-132	44.22	SKI2 homolog, superkiller viralicidic activity 2-l...	[more]
hfm1	3.184e-27	27.02	helicase for meiosis 1 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
ascc3	4.296e-23	25.52	activating signal cointegrator 1 complex subunit 3...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MTREX	0.000e+0	56.10	Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:10...	[more]
MTREX	0.000e+0	55.57	Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:10...	[more]
MTREX	0.000e+0	55.07	Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:10...	[more]
MTREX	0.000e+0	52.67	Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:10...	[more]
SKIV2L	3.576e-142	47.25	Ski2 like RNA helicase [Source:NCBI gene;Acc:10003...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mtrex	0.000e+0	55.48	Mtr4 exosome RNA helicase [Source:MGI Symbol;Acc:M...	[more]
Skiv2l	1.701e-137	41.48	superkiller viralicidic activity 2-like (S. cerevi...	[more]
Hfm1	5.446e-35	28.50	HFM1, ATP-dependent DNA helicase homolog [Source:M...	[more]
Hfm1	5.446e-35	28.50	HFM1, ATP-dependent DNA helicase homolog [Source:M...	[more]
Ascc3	7.285e-24	25.34	activating signal cointegrator 1 complex subunit 3...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9CZU3\|MTREX_MOUSE	0.000e+0	55.48	Exosome RNA helicase MTR4 OS=Mus musculus OX=10090...	[more]
sp\|P42285\|MTREX_HUMAN	0.000e+0	55.27	Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 ...	[more]
sp\|P47047\|MTR4_YEAST	0.000e+0	47.66	ATP-dependent RNA helicase DOB1 OS=Saccharomyces c...	[more]
sp\|O14232\|MTR4_SCHPO	0.000e+0	48.76	ATP-dependent RNA helicase mtr4 OS=Schizosaccharom...	[more]
sp\|Q23223\|MTR4_CAEEL	0.000e+0	48.41	mRNA transport homolog 4 OS=Caenorhabditis elegans...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4Y2HR77	0.000e+0	56.64	Exosome RNA helicase MTR4 OS=Araneus ventricosus O...	[more]
A0A4E0RHA8	0.000e+0	55.09	Putative cytoplasmic exosomal rna helicase ski2 de...	[more]
K1R517	0.000e+0	56.73	Superkiller viralicidic activity 2-like 2 OS=Crass...	[more]
A0A087U991	0.000e+0	56.40	Superkiller viralicidic activity 2-like 2 (Fragmen...	[more]
A0A1V9XLR6	0.000e+0	55.93	Superkiller viralicidic activity 2 2-like (Fragmen...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mtrex	0.000e+0	52.92	Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:10...	[more]
mtrex	0.000e+0	52.86	Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:10...	[more]
skiv2l	6.101e-139	47.48	Ski2 like RNA helicase [Source:NCBI gene;Acc:10302...	[more]
hfm1	1.955e-26	26.28	helicase for meiosis 1 [Source:ZFIN;Acc:ZDB-GENE-0...	[more]
polq	1.242e-23	25.91	DNA polymerase theta [Source:NCBI gene;Acc:1030397...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mtrex	0.000e+0	52.12	Mtr4 exosome RNA helicase [Source:ZFIN;Acc:ZDB-GEN...	[more]
ascc3	7.579e-24	25.17	activating signal cointegrator 1 complex subunit 3...	[more]
ascc3	1.202e-23	24.83	activating signal cointegrator 1 complex subunit 3...	[more]
helq	1.143e-20	26.67	helicase, POLQ like [Source:ZFIN;Acc:ZDB-GENE-0605...	[more]
helq	1.005e-16	28.57	helicase, POLQ like [Source:ZFIN;Acc:ZDB-GENE-0605...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
MTR4	0.000e+0	47.66	ATP-dependent 3'-5' RNA helicase of the DExD/H fam...	[more]
SKI2	6.043e-138	40.50	Ski complex component and putative RNA helicase; m...	[more]
HFM1	9.198e-26	26.12	Meiosis specific DNA helicase; involved in the con...	[more]
BRR2	1.180e-25	28.69	RNA-dependent ATPase RNA helicase (DEIH box); requ...	[more]
SLH1	1.900e-24	25.17	Putative RNA helicase related to Ski2p; involved i...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO43976	0.000e+0	53.37	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38196	4.871e-175	35.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46714	1.442e-25	25.95	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49146	1.809e-22	24.36	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44748	1.267e-18	24.77	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mtrex	0.000e+0	54.86	Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:10...	[more]
mtrex	0.000e+0	52.30	Mtr4 exosome RNA helicase [Source:NCBI gene;Acc:10...	[more]
skiv2l	6.767e-141	46.25	Ski2 like RNA helicase [Source:NCBI gene;Acc:10115...	[more]
skiv2l	2.906e-140	46.25	Ski2 like RNA helicase [Source:NCBI gene;Acc:10115...	[more]
skiv2l	5.779e-138	46.23	Ski2 like RNA helicase [Source:NCBI gene;Acc:10115...	[more]

BLAST of Superkiller viralicidic activity 2-like 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000004673.1	0.000e+0	97.08	SMESG000004673.1	[more]
SMESG000004886.1	0.000e+0	93.48	SMESG000004886.1	[more]
SMESG000004886.1	0.000e+0	93.19	SMESG000004886.1	[more]
SMESG000004886.1	0.000e+0	87.44	SMESG000004886.1	[more]
SMESG000063270.1	0.000e+0	45.53	SMESG000063270.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30027607 ID=SMED30027607|Name=Superkiller viralicidic activity 2-like 2|organism=Schmidtea mediterranea sexual|type=transcript|length=3197bp
CAAATTTACATTGATACAATTCAAATATTTAAATTCAATTTTTTTTTATT
ATTATGGATGATTTTTGCACTGAACTATTCCCAGATTTTGGCGTTGAAAA
CCAAAATTCAATTGAAAATGTTACAAAATTATCTGACGCCGAAATATTAA
TTAATCAAAAACGATTAGAAGATTTTATCCAGCCTTTCATTGATGAATCT
GAAAAATTAGAGACAAATGAAAAAATCCAGTCTAATTTTTTAACAAACCA
GTGCCTTTTATCTGAACATATTACTGATATAGATATCGGTAAAGCAGCAC
GAATTAAAATCCATAAAGTTTCAGGAGATGAATCATTTTCTCATGAAGTT
GCAGTTCCACCAACTATAGAGTTTGAACCTTTGAAAGAAATTGTTAATCC
TTTAAAAGCTTACCCATTCGAATTGGACAATTTCCAAAAAGCTGCTATCA
AATGTATAGATAATAGGCAATCTGTTCTTGTTTCTGCCCATACATCAGCT
GGAAAAACTGTAATTGCAGAATATGCAATTGCAAAAGCACTAAGTGATAA
ACAAAGAGTTATTTATACAACTCCTATCAAGGCTCTAAGCAATCAAAAGT
ATCGAGAATTTTCCGAAGAATTTTCCGAAGTTGGTTTATTGACTGGAGAT
GTTACTCTTTCTCCAAATGCCAGTGTACTAATTATGACTACTGAAATTCT
CCAATCCATGCTATATAGGGGTAGTTCGATTATGCGTGAGGTTGGTTGGG
TAATATTCGATGAAATTCACTACATGAGAGATCGAGAACGAGGGGTCGTA
TGGGAGGAATCGATTGTTTTGCTACCTGACGAAATTAGATGCGCTTTTCT
TAGCGCAACAATACCAAATGCTAGACAATTCGCTGAATGGATTTCGTTTT
TACATAATCAGTTGTGTCATGTCGTATTCACTGAATATCGACCTGTACCT
TTGCAGCACTACGTTTTTCCTTGCAACGGTGACGGCTTGTTGCTTGTCGT
CGATGACAAAGGCCGATTCTTGGAAGATAATTTTAAATCAGCCATGAACA
AGCTCGGTCCGAATTCCGATAGCACAAGTGAAAGAGCTGGATCAATAATG
GTTGCCAGATCACAAAAAAATGAATCAAATGTATTCAAAATTGTGAGATT
AATCATGGAACACAAACTGGAACCGCTGATAGTTTTCTCATTCAGTAAGA
AGGAATGCGAGATTTATGCCACCCAACTAGCGAAGTTAAATTTCAATTCA
GACGAAGAAACTGCTTATGTTGATGAAGTTTTTAAAAACGCGATGGAATG
TCTGTCAGATGCTGATAAAGAGTTACCTCAGGTCTTGACTTCGTTACCGC
TATTGCGTAGGGGTATTGGCGTTCATCACGGTGGTTTGCTTCCGATTTTA
AAGGAAACGGTGGAGATTTTATTTTCCGAAGGGTTACTCAAGTGTTTATT
TGCCACGGAAACGTTTGCAATGGGTCTCAATATGCCTGCTAGGACTGTCC
TGTTTACTTCGGCTAGGAAATATGACGGCTCTGAATATAGATGGATATCA
GCAAATGAATACATTCAAATGTCTGGTCGCGCTGGTAGAAGAGGAAAGGA
TGAACGAGGAACTGTAATTCTTATGGTCGATGAAACAATGAGTGACATAG
ACGCCCGTAAAATCATCCAAGGAACTCCAGACCCGCTCAATTCAGCATTC
CATATTACATATAATATGTTATTGAACCTGATGCGAGTTGAGGGAATCAA
TCCGGAATATATGATCGAACGGAGCTTCTTTCAATTTCAAAACCAAGCAT
TTGTCCCTGAAGCAGAAGAGAGTTTAAAGGCATTAATAGCCGCATATGAG
GAAATGGAAGTCGAACAGGAAGAATTGGCAGCTTCTTATTTCAAATTGGA
TGAAGCCTTACAAAATGCATACTTCAAGGAAATGGATTACATACATAAAT
CCAGTAAACTCATAAATTTCATGCAACCGGGTCGATTGATAAAAGTCAAA
CGAGACAGTGAAGATTTCGGTTGGGGAGCTGTTGTCAATATTAAGCGCCA
GCAACCGCAATTACTGAAATACTCAAGCGCCACAACCGATGAAGCTCTAT
ATCTCGTGGAATGCTTACTCACAGTTGCTGCAAGACCGAACGACAATAAA
AAAACTCCCACCAGAGCTCCGCGTCCCGGAGAGGCGAAAGTAGCAGAAGT
TACACTGTTGAAATTAAAAACTATCAGTGCAATCAGTGCTGTTCGACTCG
TAATGCCACAAGATCTCAGACCGACTGGAAATCGAGAGAAAGTCATTCAA
AATATCGAAAAGATTAAAGAGAAATTCTTTGAAATGAAATCCGAAATGAT
GAGCTCCAATAAATCGCCATCTGTGCGCAATGAAGATTTACCGATTTTAG
ACGCTATCAAGGACGTCAAAATTGATGATGAATCATTTCTCAAAATTAAA
AGGAAAATTGAAAGTTATGAAAAAAAACTCAACAATCATGAATTTTTGAA
TATATCGAATTTCGAGGAAATATTAAAAAGTTTTCGTGAAAAGGAAAAAA
AACGATTAGAAATAGAAAATTTAGAAAAGGAAATAATAAAAAAGCGCAGT
ATAATTCAAATGAACGAATTGAAAAGCCGAAAACGAGTTCTGAGACGTCT
CAATTATTGCAATGACAAAGATGTGATTGAATTGAAAGGACGAGTGGCCT
GTGAAATCACCGGAGCCGATGAATTGCTAGTCACTGAACTTCTTTTGAAA
GGAGTTTTCAATAATTTGAATCCGTCTCAAACTGCTGCCTTTGTCAGCTG
TTTGGTATTCGAAGAGAAATCATCAGAAATGCCGACATTGAATCCAGCGC
TTTCCACGGCTTTTAGAACTCTTCAAAATGAAGCGAAAATTCTAGCCGAT
ATCAGTGTCGAATGCCGATTGGACGTGAATTCAGAATCCTATATCGACAG
TTTCAAGCCACACATGATGGATGTGGTTTTGAGATGGGCTGACGGACAGA
CGTTTCTACAGCTTGTCAACAAGACAACGATATTCGAAGGCAGTATAATA
CGATGCATTCGACTTTTAGAAGAAGTTCTTCGACAGTTGGCAAATGCTGC
TAAAACGATCGGAAATACTAATTTGGAAGAGAAATTTTTGGAAGCAATCC
GGCTCATCAAGAGAGATATTGTATTTGCTGCCAGTTTGTATTTATGA

protein sequence of SMED30027607-orf-1

>SMED30027607-orf-1 ID=SMED30027607-orf-1|Name=SMED30027607-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1048bp
MDDFCTELFPDFGVENQNSIENVTKLSDAEILINQKRLEDFIQPFIDESE
KLETNEKIQSNFLTNQCLLSEHITDIDIGKAARIKIHKVSGDESFSHEVA
VPPTIEFEPLKEIVNPLKAYPFELDNFQKAAIKCIDNRQSVLVSAHTSAG
KTVIAEYAIAKALSDKQRVIYTTPIKALSNQKYREFSEEFSEVGLLTGDV
TLSPNASVLIMTTEILQSMLYRGSSIMREVGWVIFDEIHYMRDRERGVVW
EESIVLLPDEIRCAFLSATIPNARQFAEWISFLHNQLCHVVFTEYRPVPL
QHYVFPCNGDGLLLVVDDKGRFLEDNFKSAMNKLGPNSDSTSERAGSIMV
ARSQKNESNVFKIVRLIMEHKLEPLIVFSFSKKECEIYATQLAKLNFNSD
EETAYVDEVFKNAMECLSDADKELPQVLTSLPLLRRGIGVHHGGLLPILK
ETVEILFSEGLLKCLFATETFAMGLNMPARTVLFTSARKYDGSEYRWISA
NEYIQMSGRAGRRGKDERGTVILMVDETMSDIDARKIIQGTPDPLNSAFH
ITYNMLLNLMRVEGINPEYMIERSFFQFQNQAFVPEAEESLKALIAAYEE
MEVEQEELAASYFKLDEALQNAYFKEMDYIHKSSKLINFMQPGRLIKVKR
DSEDFGWGAVVNIKRQQPQLLKYSSATTDEALYLVECLLTVAARPNDNKK
TPTRAPRPGEAKVAEVTLLKLKTISAISAVRLVMPQDLRPTGNREKVIQN
IEKIKEKFFEMKSEMMSSNKSPSVRNEDLPILDAIKDVKIDDESFLKIKR
KIESYEKKLNNHEFLNISNFEEILKSFREKEKKRLEIENLEKEIIKKRSI
IQMNELKSRKRVLRRLNYCNDKDVIELKGRVACEITGADELLVTELLLKG
VFNNLNPSQTAAFVSCLVFEEKSSEMPTLNPALSTAFRTLQNEAKILADI
SVECRLDVNSESYIDSFKPHMMDVVLRWADGQTFLQLVNKTTIFEGSIIR
CIRLLEEVLRQLANAAKTIGNTNLEEKFLEAIRLIKRDIVFAASLYL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **molecular function**
Term	Definition
GO:0005524	ATP binding
GO:0003723	RNA binding
GO:0003724	RNA helicase activity
GO:0003676	nucleic acid binding
GO:0000166	nucleotide binding
GO:0004004	ATP-dependent RNA helicase activity
GO:0004386	helicase activity
GO:0016787	hydrolase activity

Vocabulary: **biological process**
Term	Definition
GO:0006401	RNA catabolic process
GO:0000460	maturation of 5.8S rRNA
GO:0006364	rRNA processing
GO:0006397	mRNA processing
GO:0008380	RNA splicing

Vocabulary: **INTERPRO**
Term	Definition
IPR012961	Ski2_C
IPR014001	Helicase_ATP-bd
IPR001650	Helicase_C
IPR011545	DEAD/DEAH_box_helicase_dom
IPR027417	P-loop_NTPase
IPR025696	rRNA_proc-arch_dom
IPR016438	Ski2-like

Vocabulary: **cellular component**
Term	Definition
GO:0000178	exosome (RNase complex)
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005681	spliceosomal complex
GO:0005730	nucleolus
GO:0071013	catalytic step 2 spliceosome