Peptidyl-glycine alpha-amidating monooxygenase

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPSKTI----SAKTLQNYNFDIDVLK---------MDKNWKVNKKL---------GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVD-SRGYVFVADGYCNNRVVCFYPNGTYIEEW--QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSD---GDIRG-SSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAK 2032
            L ++MPGV    +D Y C S  +P  +E ++++ ++P A+    HHMLLFGC+ P ST   + C          IL+ WAR+A     P   G  VGG++   YFVLQVHY   +   D     SG+ L L+  P   + G++L+ S    I    + VN D+SC YK N   +  A+R H H LG+ +SGY+V   +GQ  LIG+ +PQ PQ FY     V +  GD+L ARC+F   G+   T IG T  DEMCN YIM   +      SF  C  N   D+++ IP    E + P P    +           Y   I +L+         +D+++ + + L         G+VSGV++          ++++ HRG H W   SF  K VYQ+    PI + TI+ +DP +  VL+ + + +FY+PHG++  KDG Y W+TDVA HQV + +  +      + P ++LG+   PG D NHFC+P+ VAVD   G ++V+DGYCN+R+V F P+G +I +W  +S     +    T+    +       + VADREN +I  F  D       I   S   +++ I Y P   L++ +      GD      F  N ++ ++    KP      F  PHD+  +++G  +++ + H   V KF +  K
Sbjct:   59 LDIRMPGVTPKQSDTYFCMSMRIPV-DEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYK-NYPMHVFAYRVHTHHLGKVVSGYRV--RNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME-AKHAVSFMTCTQNVAPDMFRTIPP---EANIPIPVKSDMVMMHEHHKETEYKDKIPLLQQPKREEEEVLDQDFHMEEALDWPGVYLLPGQVSGVALDPKN------NLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNY-WVTDVALHQVFKLDPNN-----KEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKHSSFGRNVFAISYIPG--LLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKP--VRKHFDMPHDIVASEDGT-VYIGDAHTNTVWKFTLTEK 704          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y C S  +P  +E ++++ ++P A+    HHMLLFGC+ P ST   + C          IL+ WAR+A     P   G  VGG++   YFVLQVHY   +   D     SG+ L L+  P   + G++L+ S    I    + VN D+SC YK N   +  A+R H H LG+ +SGY+V   +GQ  LIG+ +PQ PQ FY     V +  GD+L ARC+F   G+   T IG T  DEMCN YIM   +      SF  C  N   D+++ IP
Sbjct:   59 LDIRMPGVTPKQSDTYFCMSMRIPV-DEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYK-NYPMHVFAYRVHTHHLGKVVSGYRV--RNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME-AKHAVSFMTCTQNVAPDMFRTIP 342          

Query: 1124 GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVD-SRGYVFVADGYCNNRVVCFYPNGTYIEEW--QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSD---GDIRG-SSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAK 2032
            G+VSGV++          ++++ HRG H W   SF  K VYQ+    PI + TI+ +DP +  VL+ + + +FY+PHG++  KDG Y W+TDVA HQV + +  +      + P ++LG+   PG D NHFC+P+ VAVD   G ++V+DGYCN+R+V F P+G +I +W  +S     +    T+    +       + VADREN +I  F  D       I   S   +++ I Y P   L++ +      GD      F  N ++ ++    KP      F  PHD+  +++G  +++ + H   V KF +  K
Sbjct:  512 GQVSGVALDPKN------NLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNY-WVTDVALHQVFKLDPNN-----KEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKHSSFGRNVFAISYIPG--LLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRK--HFDMPHDIVASEDGT-VYIGDAHTNTVWKFTLTEK 811          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y C S  +P  +E ++++ ++P A+    HHMLLFGC+ P ST   + C          IL+ WAR+A     P   G  VGG++   YFVLQVHY   +   D     SG+ L L+  P   + G++L+ S    I    + VN D+SC YK N   +  A+R H H LG+ +SGY+V   +GQ  LIG+ +PQ PQ FY     V +  GD+L ARC+F   G+   T IG T  DEMCN YIM   +      SF  C  N   D+++ IP
Sbjct:   59 LDIRMPGVTPKQSDTYFCMSMRIPV-DEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYK-NYPMHVFAYRVHTHHLGKVVSGYRV--RNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME-AKHAVSFMTCTQNVAPDMFRTIP 342          

Query: 1124 GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVD-SRGYVFVADGYCNNRVVCFYPNGTYIEEW--QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSD---GDIRG-SSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAK 2032
            G+VSGV++          ++++ HRG H W   SF  K VYQ+    PI + TI+ +DP +  VL+ + + +FY+PHG++  KDG Y W+TDVA HQV + +  +      + P ++LG+   PG D NHFC+P+ VAVD   G ++V+DGYCN+R+V F P+G +I +W  +S     +    T+    +       + VADREN +I  F  D       I   S   +++ I Y P   L++ +      GD      F  N ++ ++    KP      F  PHD+  +++G  +++ + H   V KF +  K
Sbjct:  512 GQVSGVALDPKN------NLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNY-WVTDVALHQVFKLDPNN-----KEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKHSSFGRNVFAISYIPG--LLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKPVRK--HFDMPHDIVASEDGT-VYIGDAHTNTVWKFTLTEK 811          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y C S  +P  +E ++++ ++P A+    HHMLLFGC+ P ST   + C          IL+ WAR+A     P   G  VGG++   YFVLQVHY   +   D     SG+ L L+  P   + G++L+ S    I    + VN D+SC YK N   +  A+R H H LG+ +SGY+V   +GQ  LIG+ +PQ PQ FY     V +  GD+L ARC+F   G+   T IG T  DEMCN YIM   +      SF  C  N   D+++ IP
Sbjct:   59 LDIRMPGVTPKQSDTYFCMSMRIPV-DEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYK-NYPMHVFAYRVHTHHLGKVVSGYRV--RNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME-AKHAVSFMTCTQNVAPDMFRTIP 342          

Query: 1124 GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVD-SRGYVFVADGYCNNRVVCFYPNGTYIEEW--QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSD---GDIRG-SSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAK 2032
            G+VSGV++          ++++ HRG H W   SF  K VYQ+    PI + TI+ +DP +  VL+ + + +FY+PHG++  KDG Y W+TDVA HQV + +  +      + P ++LG+   PG D NHFC+P+ VAVD   G ++V+DGYCN+R+V F P+G +I +W  +S     +    T+    +       + VADREN +I  F  D       I   S   +++ I Y P   L++ +      GD      F  N ++ ++    KP      F  PHD+  +++G  +++ + H   V KF +  K
Sbjct:  512 GQVSGVALDPKN------NLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNY-WVTDVALHQVFKLDPNN-----KEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKHSSFGRNVFAISYIPG--LLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKP--VRKHFDMPHDIVASEDGT-VYIGDAHTNTVWKFTLTEK 811          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y C S  +P  +E ++++ ++P A+    HHMLLFGC+ P ST   + C          IL+ WAR+A     P   G  VGG++   YFVLQVHY   +   D     SG+ L L+  P   + G++L+ S    I    + VN D+SC YK N   +  A+R H H LG+ +SGY+V   +GQ  LIG+ +PQ PQ FY     V +  GD+L ARC+F   G+   T IG T  DEMCN YIM   +      SF  C  N   D+++ IP
Sbjct:   59 LDIRMPGVTPKQSDTYFCMSMRIPV-DEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYK-NYPMHVFAYRVHTHHLGKVVSGYRV--RNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME-AKHAVSFMTCTQNVAPDMFRTIP 342          

Query: 1124 GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVD-SRGYVFVADGYCNNRVVCFYPNGTYIEEW--QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSD---GDIRG-SSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAK 2032
            G+VSGV++          ++++ HRG H W   SF  K VYQ+    PI + TI+ +DP +  VL+ + + +FY+PHG++  KDG Y W+TDVA HQV + +  +      + P ++LG+   PG D NHFC+P+ VAVD   G ++V+DGYCN+R+V F P+G +I +W  +S     +    T+    +       + VADREN +I  F  D       I   S   +++ I Y P   L++ +      GD      F  N ++ ++    KP      F  PHD+  +++G  +++ + H   V KF +  K
Sbjct:  512 GQVSGVALDPKN------NLVIFHRGDHVWDGNSFDSKFVYQQIGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNY-WVTDVALHQVFKLDPNN-----KEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKHSSFGRNVFAISYIPG--LLFAVNGKPHFGDQEPVQGFVMNFSNGEIIDIFKP--VRKHFDMPHDIVASEDGT-VYIGDAHTNTVWKFTLTEK 811          

Query:  137 EKLKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICE-NSHEKILFGWARDAKSFHYPSNTGMAVGGKSN-INYFVLQVHYLKP--TTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECG--GNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDKNWKVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKDVYQEDLD-SPISDYTIVEVDPVSGN---VLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGII-------KFTHIFRKSLSIYGIKYNPKNRLIYGITSDG--DIRGSS------FTFNTTS----SQMKPWNTDYSFRAPHDLCLADNGKFIFVAEL 1993
            +K  +QM G      D+Y+  S          Y+V++EP+A++   HHMLL+GC+ P S +  +     C       IL+ WAR+A +   P +   +VG + + I YFVLQVHY +P    + D SG+ + +S K P  +  + +LF     I PQ      +++C ++ ++  +  AFRTH HA+GR +S +    +DG    IGK NPQWPQ F    +++ I  GD + A C FDS  K+    +G+  +DEMCNFY MM   +   +N + +      ++     + P    E  P  P  +  + ++     F I    + +N     KLG+V+G++    +Q      +LV  R    W   +F  D Y   LD  PI+D  I+ +   SGN   + R+   G FY+PHGI   KDG +++ TDV  H V ++ + + ++L +   S   G+  +PG D +H+CKP+ +       ++V DGYCN+RVV    NG  I ++    P        +  D   D +  ++ V DREN ++      G +        FT+I+  + S     +    R I G  ++G     G S      + F  T+     QM P      F  PH L +  +G  IFV ++
Sbjct:   33 QKFTIQMIGYSPQKTDDYVAVSIEA----TPGYVVAFEPMAHADRVHHMLLYGCTMPASEQGFWRGMETCGWGGGSYILYAWARNAPNLVLPKDVAFSVGHEQDGIKYFVLQVHYAQPFAGEVHDFSGVTMHISQKKPMNLAAV-MLFVSGTPIPPQLPAFQNNITCMFESSTPIHPFAFRTHTHAMGRLVSAF--FKHDGHWTKIGKRNPQWPQLFEGIPSKLMIGSGDQMSASCRFDSMDKNRTVNMGAMGVDEMCNFY-MMFHYDAKLDNPYPQGAICAKDYPSKMIDYPKDGFELLPSRPELEHHAHQS--KVPFGIVQEAIHENLG-GVKLGQVAGLAFNNEQQ------LLVFQRAGRVWDASTF--DNYNILLDKKPIADPVILVIS-YSGNQTKLERKLGGGQFYLPHGIYVDKDG-FVYTTDVGSHTVAKWKI-EGNELKNIWTS---GELLMPGSDQHHYCKPTGI-TRVEDQLYVTDGYCNSRVVVLDLNGKRIRQFGL--PGEDAGQFNLPHDIVSDSAGRLL-VTDRENGRVQHMTTQGHVIEEFKSTMFTNIYSAA-SHEDYVFMVPGRPIMGHETEGIAVFVGRSGTGLIEYAFGPTTKGKREQMGP-----QFGQPHCLRVCPDGGHIFVGDI 646          

Query:   89 LRDLFMFLVVIYLANGEKLKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC-----------RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLN---DGQIELIGKGNPQWPQTF--YKSAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTK-NTGEENSFSECGGNEFK 973
            L    +        N EK +++MPGV+    D Y+C+S  +   ++ +Y+  ++ L     AHH+LLFGC  P S E  + C           R+    S   IL+ WA DA     P + G  VGG SNI + V+QVHY+      D++GL +  + +P   +    LL +  G   P+ +  + + +C  + +   +  A+RTH H  G+ +SG+ V  +   +   +LIG+ +PQ  Q F   +   + I+ GD++ ARC+  +     ++ +G+T  DEMCNFYIM  T     ++N+    G  ++K
Sbjct:    7 LSSCALLAFATSFCNAEKSQIRMPGVVP-EADSYLCTSLEL--SDQENYLTGFKALTTKGTAHHILLFGCEEPGSDELVWDCGEMNKPDDEMPRAPTCGSKPAILYAWALDAPPLELPQDVGFRVGGDSNIRHLVMQVHYMHSKQEPDETGLEITHTEEPQPKLAATMLLVT--GGTLPRNKTESFETACMIEEDVVMHPFAYRTHTHRHGKEVSGWLVKEDQKHEDHWKLIGRRDPQLAQMFVPVEDQAMTIQQGDMVTARCILQNNENRDIS-MGATEEDEMCNFYIMYWTDGEVMQDNTCYSPGAPDYK 312          

Query: 1112 NKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIV--LGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEW-----QSQDPMFIV-HSITIKEDESGDISKNIVWVADRENRKIIGFGY---DG---------IIKFTHIFRKSLSIYGIKYNPKNRLIYGITSDG-DIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEI 2023
            +K++G+VSG+++      K G+ ++  HR    W E+SF   + + +DL   I++ TI  +      V+ E   G+FYMPHG+T   +G Y W+TDV  HQV + +         KT  IV  LG++ +PG D  HFCKP+ VAV   G++FVADGYCN+R++ F   G  + +      ++Q   F+V HS+++ ED       NIV VADREN+++  F     +G         I   T I R    ++ I+   +   + G+T +  D+    F+ +  + + + +      R  H L +A +G  +FV++L   ++++  +
Sbjct:   56 SKEIGQVSGLAV-----NKNGH-IVAFHRSGRVWDEKSFNDHETFNKDL-GVINNKTIAIISR-EKKVIDEFGAGLFYMPHGLTIDNNGDY-WVTDVGSHQVHKIDA--------KTQKIVMSLGEKMVPGEDQAHFCKPTDVAVAKNGHIFVADGYCNSRILKFDAKGNLMAQINAATEENQPSEFVVPHSLSLIED------MNIVCVADRENQRVQCFSAGLSEGDRTLPTGIPITSATDIGR----VFAIR--EREHYLIGVTGNSEDVEAQMFSIDMQTGKTETFAK--GVRNTHALAIAADG-VMFVSQLEPSRILEIRL 349          

Query: 1112 NKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIV--LGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEW-----QSQDPMFIV-HSITIKEDESGDISKNIVWVADRENRKIIGFGY---DG---------IIKFTHIFRKSLSIYGIKYNPKNRLIYGITSDG-DIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEI 2023
            +K++G+VSG+++      K G+ ++  HR    W E+SF   + + +DL   I++ TI  +      V+ E   G+FYMPHG+T   +G Y W+TDV  HQV + +         KT  IV  LG++ +PG D  HFCKP+ VAV   G++FVADGYCN+R++ F   G  + +      ++Q   F+V HS+++ ED       NIV VADREN+++  F     +G         I   T I R    ++ I+   +   + G+T +  D+    F+ +  + + + +      R  H L +A +G  +FV++L   ++++  +
Sbjct:   56 SKEIGQVSGLAV-----NKNGH-IVAFHRSGRVWDEKSFNDHETFNKDL-GVINNKTIAIISR-EKKVIDEFGAGLFYMPHGLTIDNNGDY-WVTDVGSHQVHKIDA--------KTQKIVMSLGEKMVPGEDQAHFCKPTDVAVAKNGHIFVADGYCNSRILKFDAKGNLMAQINAATEENQPSEFVVPHSLSLIED------MNIVCVADRENQRVQCFSAGLSEGDRTLPTGIPITSATDIGR----VFAIR--EREHYLIGVTGNSEDVEAQMFSIDMQTGKTETFAK--GVRNTHALAIAADG-VMFVSQLEPSRILEIRL 349          

Query:  191 ICSSFPVPNHNENSYIVSYEPL---ANSSIAHHMLLFGCS------SPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTT---IEDKSGLLLELSSKPPDYVVGIF---LLFSYYGKIQPQTRKVNLDVSCRYKGNSE-----AYTLAFRTHAHALGRSI--SGYKVSLNDGQIELIGKGNPQWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYI 907
            I    P    N   ++V  EP     N  + HHM +F C       S    +P  P +S    S   ++  WA      HYP   G+ +GGK    Y ++++HY  P     + D SG    ++ +   Y  GI    L++S    + P  +   ++  C  +             A + HAH  GR +  S Y+  +  G +      +P W         V++ PGD L+  C++D+  +  VT  G   +DEMC  YI
Sbjct:  209 IIRKMPFDTVNNMYHVVRMEPYVTPGNEHLVHHMEIFMCRDEVEEWSGSCNDPKKPPKS---KSCSHVIAAWAMGEGPIHYPKEAGLPIGGKGKNAYVMVEIHYNNPELHKGVIDSSGFQFFVTGQLRKYDAGIMELGLIYSDANSVPPNQKAWAMNGYCPSQCTKNLPEEGINIFASQLHAHLTGRKLFTSQYRSGVRIGDVNRDEHYSPHWQHLQQLRPVVKVMPGDTLVTTCVYDTRKRSKVTFGGYRIVDEMCVNYI 466          

Query:  155 MPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHE------------KILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIE----DKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLN-DGQIEL--IGKGNPQWPQTFYKSAQVQ-IKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIM 910
            MP V     D Y+C+   V +     YIV + P A  + AHHMLL+GC  P +++ ++ C  +   S E            +I++ WARDA+  + P   G  VG  S I Y VLQVHY      +    D SG+ L+ + +P   + G  LL +  G+I P  +  +L+ +C        +  A+R H H LG+ +SGY+V  N DG+ E   +GK +P  PQ FY ++    I  GD +  RC   ST +   T+IG T+ DEMCNFY+M
Sbjct:   56 MPNVSPQTPDLYLCTPIKV-DPTTTYYIVGFNPNATMNTAHHMLLYGCGEPGTSKTTWNCGEMNRASQEESASPCGPHSNSQIVYAWARDAQKLNLPEGVGFKVGKNSPIKYLVLQVHYAHIDKFKDGSTDDSGVFLDYTEEPRKKLAGTLLLGT-DGQI-PAMKTEHLETACEVNEQKVLHPFAYRVHTHGLGKVVSGYRVRTNSDGEQEWLQLGKRDPLTPQMFYNTSNTDPIIEGDKIAVRCTMQST-RHRTTKIGPTNEDEMCNFYLM 323          

Query:  155 MPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHE------------KILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIE----DKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLN-DGQIEL--IGKGNPQWPQTFYKSAQVQ-IKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIM 910
            MP V     D Y+C+   V +     YIV + P A  + AHHMLL+GC  P +++ ++ C  +   S E            +I++ WARDA+  + P   G  VG  S I Y VLQVHY      +    D SG+ L+ + +P   + G  LL +  G+I P  +  +L+ +C        +  A+R H H LG+ +SGY+V  N DG+ E   +GK +P  PQ FY ++    I  GD +  RC   ST +   T+IG T+ DEMCNFY+M
Sbjct:   56 MPNVSPQTPDLYLCTPIKV-DPTTTYYIVGFNPNATMNTAHHMLLYGCGEPGTSKTTWNCGEMNRASQEESASPCGPHSNSQIVYAWARDAQKLNLPEGVGFKVGKNSPIKYLVLQVHYAHIDKFKDGSTDDSGVFLDYTEEPRKKLAGTLLLGT-DGQI-PAMKTEHLETACEVNEQKVLHPFAYRVHTHGLGKVVSGYRVRTNSDGEQEWLQLGKRDPLTPQMFYNTSNTDPIIEGDKIAVRCTMQST-RHRTTKIGPTNEDEMCNFYLM 323          

Query:  995 SYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDKN------WKVNK-KLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEW------------QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGF-GYDGIIKFTHIFRKSL---SIYGIKYNPKNR----LIYGITSDGDIRGS------SFTFNTTSSQM--KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKF 2017
            S + + + P PP +T+        N   ++ K++        W  N  KLG V+ VS      +    +V++ HR +  W + +F  ++ YQE    PI + TI+ ++P +G V  +  +  FYMPHG+T   +   +W+TDVA HQV +F  R      D  P++ LG  F PG     FCKP+ VAV   G  FVADGYCN R++ +   G  I  W              Q+   I H++T+  +        ++  ADREN ++  F   +G   F   +   L    ++ + Y P       ++ G T++  I          F  +  S Q+  K    +  F+ PHD+ +  +G  I+VAEL+  ++ KF
Sbjct:   66 SGATQLNWPQPPKQTVP-------NVKTELAKLNNTYVYQNAWPANNVKLGAVTAVS------FDKAGNVVIFHRVNRVWGQTTFDNRNQYQEKYRGPIRESTILALEPATGKVQYDWGKNFFYMPHGLTVDPEDN-VWLTDVAMHQVFKFPPRGG----DGKPALTLGDAFQPGSGRK-FCKPTSVAVLDNGDFFVADGYCNARILKYSRKGELILFWGQNTFSGISYDVAPQNFFAIPHALTLVPE------LQLLCAADRENGRVQCFLSSNGT--FHSQYHNQLIGDRLFSMAYTPAAGGQLVIVNGPTAELGIHPEHYNEVHGFVLSMRSKQLVSKFGPNNLQFQNPHDVAVTADGNEIYVAELNPMRIHKF 415          

Query:  995 SYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDKN------WKVNK-KLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEW------------QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGF-GYDGIIKFTHIFRKSL---SIYGIKYNPKNR----LIYGITSDGDIRGS------SFTFNTTSSQM--KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKF---EIAAKSSTKHHQHSVGNNFNQ-----------IHDMVKQINPVYIGVLMVAVTVFILICIVTMKYYRRC 2191
            S + + + P PP +T+        N   ++ K++        W  N  KLG V+ VS      +    +V++ HR +  W + +F  ++ YQE    PI + TI+ ++P +G V  +  +  FYMPHG+T   +   +W+TDVA HQV +F  R      D  P++ LG  F PG     FCKP+ VAV   G  FVADGYCN R++ +   G  I  W              Q+   I H++T+  +        ++  ADREN ++  F   +G   F   +   L    ++ + Y P       ++ G T++  I          F  +  S Q+  K    +  F+ PHD+ +  +G  I+VAEL+  ++ KF    +A   S    + S  +  +Q           +H    +   V   +L+ A + F L  I   +  R C
Sbjct:   66 SGATQLNWPQPPKQTVP-------NVKTELAKLNNTYVYQNAWPANNVKLGAVTAVS------FDKAGNVVIFHRVNRVWGQTTFDNRNQYQEKYRGPIRESTILALEPATGKVQYDWGKNFFYMPHGLTVDPEDN-VWLTDVAMHQVFKFPPRGG----DGKPALTLGDAFQPGSGRK-FCKPTSVAVLDNGDFFVADGYCNARILKYSRKGELILFWGQNTFSGISYDVAPQNFFAIPHALTLVPE------LQLLCAADRENGRVQCFLSSNGT--FHSQYHNQLIGDRLFSMAYTPAAGGQLVIVNGPTAELGIHPEHYNEVHGFVLSMRSKQLVSKFGPNNLQFQNPHDVAVTADGNEIYVAELNPMRIHKFVHRSLAKPMSLSASKDSRDSAISQAVGGDQVPAVAVHHPSGKAILVASLMLLFAGSTFALALIFARRRKRGC 487          

Query:  995 SYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDKN------WKVNK-KLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEW------------QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGF-GYDGIIKFTHIFRKSL---SIYGIKYNPKNR----LIYGITSDGDIRGS------SFTFNTTSSQM--KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKF---EIAAKSSTKHHQHSVGNNFNQ-----------IHDMVKQINPVYIGVLMVAVTVFILICIVTMKYYRRC 2191
            S + + + P PP +T+        N   ++ K++        W  N  KLG V+ VS      +    +V++ HR +  W + +F  ++ YQE    PI + TI+ ++P +G V  +  +  FYMPHG+T   +   +W+TDVA HQV +F  R      D  P++ LG  F PG     FCKP+ VAV   G  FVADGYCN R++ +   G  I  W              Q+   I H++T+  +        ++  ADREN ++  F   +G   F   +   L    ++ + Y P       ++ G T++  I          F  +  S Q+  K    +  F+ PHD+ +  +G  I+VAEL+  ++ KF    +A   S    + S  +  +Q           +H    +   V   +L+ A + F L  I   +  R C
Sbjct:   66 SGATQLNWPQPPKQTVP-------NVKTELAKLNNTYVYQNAWPANNVKLGAVTAVS------FDKAGNVVIFHRVNRVWGQTTFDNRNQYQEKYRGPIRESTILALEPATGKVQYDWGKNFFYMPHGLTVDPEDN-VWLTDVAMHQVFKFPPRGG----DGKPALTLGDAFQPGSGRK-FCKPTSVAVLDNGDFFVADGYCNARILKYSRKGELILFWGQNTFSGISYDVAPQNFFAIPHALTLVPE------LQLLCAADRENGRVQCFLSSNGT--FHSQYHNQLIGDRLFSMAYTPAAGGQLVIVNGPTAELGIHPEHYNEVHGFVLSMRSKQLVSKFGPNNLQFQNPHDVAVTADGNEIYVAELNPMRIHKFVHRSLAKPMSLSASKDSRDSAISQAVGGDQVPAVAVHHPSGKAILVASLMLLFAGSTFALALIFARRRKRGC 487          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC---RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNP--PSKTISAK----------TLQNYNFDIDV------LKMDKNW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQV 1414
            L +++PGV+   +D Y C + PVP   E +YIV + P A+   AHHM+L+GC +P++T+  + C      C +   KI++ WAR+A     P + G  VGG + INYFVLQ+HY       D     SGL L ++SKP  ++ G++L+ S    I P  +  N D++C Y  +S  Y  AFRTH H+LG+ +SGY+V   +GQ   IG+ +P  PQ FY +   + +K GDIL ARC+F   G+ + T+IG T  DEMCNFYIM    NT     +  C  +   +L++NIPS   E + P P  P   +S K           LQ    D +V      L    +W + + +LG+VSG+++           +++ HRG H W   SF +  +YQ     PI   TI+ VD V G VL+ + + +FY+PHGIT   D  Y W+TDVA HQV
Sbjct:   60 LDIRLPGVVPTESDSYYCMAVPVPTSRE-AYIVDFVPHASMDTAHHMILYGCKTPYATQGYWDCGKELGTCRD-QAKIMYAWARNAPPTKLPKDVGFKVGGDTRINYFVLQIHYGDVNNFRDHHRDCSGLSLRMTSKPQPFIAGMYLMMSVDTLIPPGKKVTNADIACTYT-SSPMYPFAFRTHTHSLGKVVSGYRV--RNGQWTQIGRQSPLLPQAFYPATNTIDVKDGDILAARCVFTGEGRTTTTQIGGTSNDEMCNFYIMYYMDNT-HAVPYMNCRDDGSSELFRNIPS---EANIPIPVRPDHMMSMKHESSPQKDAVELQEPKRDEEVQDQGAHLVEVSDWPEADLQLGQVSGLAL------NSNGDLVIFHRGDHIWGIDSFNMNAIYQLRDQGPIQQSTILLVDSVKGKVLKASGKNMFYLPHGITTDHDDNY-WVTDVALHQV 495          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC---RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPS 997
            L +++PGV+   +D Y C + PVP   E +YIV + P A+   AHHM+L+GC +P++T+  + C      C +   KI++ WAR+A     P + G  VGG + INYFVLQ+HY       D     SGL L ++SKP  ++ G++L+ S    I P  +  N D++C Y  +S  Y  AFRTH H+LG+ +SGY+V   +GQ   IG+ +P  PQ FY +   + +K GDIL ARC+F   G+ + T+IG T  DEMCNFYIM    NT     +  C  +   +L++NIPS
Sbjct:   60 LDIRLPGVVPTESDSYYCMAVPVPTSRE-AYIVDFVPHASMDTAHHMILYGCKTPYATQGYWDCGKELGTCRD-QAKIMYAWARNAPPTKLPKDVGFKVGGDTRINYFVLQIHYGDVNNFRDHHRDCSGLSLRMTSKPQPFIAGMYLMMSVDTLIPPGKKVTNADIACTYT-SSPMYPFAFRTHTHSLGKVVSGYRV--RNGQWTQIGRQSPLLPQAFYPATNTIDVKDGDILAARCVFTGEGRTTTTQIGGTSNDEMCNFYIMYYMDNT-HAVPYMNCRDDGSSELFRNIPS 346          

Query: 1100 NW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDS-RGYVFVADGYCNNRVVCFYPNGTYIEEWQSQD--------------PMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL---SIYGIKYNP-KNRLIYGITSDGDIRGSS----FTFNTTSSQ-MKPWNTDYS-FRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTK 2044
            +W + + +LG+VSG+++           +++ HRG H W   SF +  +YQ     PI   TI+ VD V G VL+ + + +FY+PHGIT   D  Y W+TDVA HQV + +     + +     +VLG+ F PG D  HFC+P+ VAVD   G V+V+DGYCN+R++ F P G YI  W +                P  I HS+T   D      K  + VADR+N +I  F  D   +F    +K +    ++ I Y+P +  L+Y +  +     ++    F  N +S + +  ++ D   F+ PHD+ +  +G  +FV +     V+KF  +AK+  +
Sbjct:  497 DWPEADLQLGQVSGLAL------NSNGDLVIFHRGDHIWGIDSFNMNAIYQLRDQGPIQQSTILLVDSVKGKVLKASGKNMFYLPHGITTDHDDNY-WVTDVALHQVFKLSGNGKDQQL-----LVLGEAFEPGSDKKHFCQPTDVAVDPVTGNVYVSDGYCNSRILQFSPEGKYISHWGADQRKSALSSALPGRRVPFRIPHSLTFLPD------KRELCVADRDNGRIQCFMAD-TGEFVKEIKKDVFGGEVFAIAYSPAQGGLLYAVNGEPPYGQAAPLQGFVINYSSKEILDSFSPDTQVFKLPHDIVVTADGT-VFVGDAAADSVMKFIQSAKAEHR 818          

Query:  890 MCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNP--PSKTISAK----------TLQNYNFDIDV------LKMDKNW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDS-RGYVFVADGYCNNRVVCFYPNGTYIEEW-------QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL---SIYGIKYNP-KNRLIYGITSDGDIRGSS----FTFNTTSSQ-MKPWNTDYS-FRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTK 2044
            MCNFYIM    NT     +  C  +   +L++NIPS   E + P P  P   +S K           LQ    D +V      L    +W + + +LG+VSG+++           +++ HRG H W   SF +  +YQ     PI   TI+ VD V G VL+ + + +FY+PHGIT   D  Y W+TDVA HQV + +     + +     +VLG+ F PG D  HFC+P+ VAVD   G V+V+DGYCN+R++ F P G YI  W       + + P  I HS+T   D      K  + VADR+N +I  F  D   +F    +K +    ++ I Y+P +  L+Y +  +     ++    F  N +S + +  ++ D   F+ PHD+ +  +G  +FV +     V+KF  +AK+  +
Sbjct:    1 MCNFYIMYYMDNT-HAVPYMNCRDDGSSELFRNIPS---EANIPIPVRPDHMMSMKHESSPQKDAVELQEPKRDEEVQDQGAHLVEVSDWPEADLQLGQVSGLAL------NSNGDLVIFHRGDHIWGIDSFNMNAIYQLRDQGPIQQSTILLVDSVKGKVLKASGKNMFYLPHGITTDHDDNY-WVTDVALHQVFKLSGNGKDQQL-----LVLGEAFEPGSDKKHFCQPTDVAVDPVTGNVYVSDGYCNSRILQFSPEGKYISHWGAGSSDRKRRVPFRIPHSLTFLPD------KRELCVADRDNGRIQCFMAD-TGEFVKEIKKDVFGGEVFAIAYSPAQGGLLYAVNGEPPYGQAAPLQGFVINYSSKEILDSFSPDTQVFKLPHDIVVTADGT-VFVGDAAADSVMKFIQSAKAEHR 399          

Query: 1100 NW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDS-RGYVFVADGYCNNRVVCFYPNGTYIEEW-------QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL---SIYGIKYNP-KNRLIYGITSDGDIRGSS----FTFNTTSSQ-MKPWNTDYS-FRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTK 2044
            +W + + +LG+VSG+++           +++ HRG H W   SF +  +YQ     PI   TI+ VD V G VL+ + + +FY+PHGIT   D  Y W+TDVA HQV + +     + +     +VLG+ F PG D  HFC+P+ VAVD   G V+V+DGYCN+R++ F P G YI  W       + + P  I HS+T   D      K  + VADR+N +I  F  D   +F    +K +    ++ I Y+P +  L+Y +  +     ++    F  N +S + +  ++ D   F+ PHD+ +  +G  +FV +     V+KF  +AK+  +
Sbjct:  186 DWPEADLQLGQVSGLAL------NSNGDLVIFHRGDHIWGIDSFNMNAIYQLRDQGPIQQSTILLVDSVKGKVLKASGKNMFYLPHGITTDHDDNY-WVTDVALHQVFKLSGNGKDQQL-----LVLGEAFEPGSDKKHFCQPTDVAVDPVTGNVYVSDGYCNSRILQFSPEGKYISHWGAGSSDRKRRVPFRIPHSLTFLPD------KRELCVADRDNGRIQCFMAD-TGEFVKEIKKDVFGGEVFAIAYSPAQGGLLYAVNGEPPYGQAAPLQGFVINYSSKEILDSFSPDTQVFKLPHDIVVTADGT-VFVGDAAADSVMKFIQSAKAEHR 500          

Query:  164 VLAMNNDEYICSSFPVPNHNENSYIVSYEPL---ANSSIAHHMLLFGCSSPFSTEPSFP--CRSICE----NSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTI---EDKSGLLLELSSKPPDYVVGIF---LLFSYYGKIQPQTRKVNLDVSCRYKGNSEA------YTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-----SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYI 907
            ++      Y C  + +P +   ++IV YE +    N +I HH+ +F CS      P +   C S  +    N    +L  WA  A+ F+YP++ G+ +GG+ +  +  L+VHY  P  +    D SG+ L  S     +  GI    L+++    I P+ R   L   C  K    A      +  A + H H  G    G +  L  G  E+      +   T Y+        V + PGD L+  C F++  +  VT  G   M+EMC  Y+
Sbjct:  218 IIPTQETTYWCHIYQLPPNLPKNHIVMYESVITPGNEAIVHHIEVFECSPQMDIVPQYSGSCDSKMKPRNLNYCRHVLAAWAMGAEPFYYPADAGLPMGGEGSSRFLRLEVHYHNPLLLSGRRDSSGIRLWYSPSLRRFDAGIMELGLVYTPVMAIPPRQRSFQLTGYCTAKCTQTALPVGGIHIFASQLHTHLAGL---GVRTVLVRGGQEVEVVQEDKHFSTHYQIIRVLQKMVTVLPGDALLTTCRFNTEDRSKVTVGGFGIMEEMCVNYV 488          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNP----------------PSKTIS---AKTLQNYNFDIDV-LKMDKNWK-VNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKD-VYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDS-RGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDG---IIKFTH------IFRKSLSIYGIKYNPKNRLIYGITSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKF 2017
            L ++MPGV    +D Y+C S+ +P  +E +Y+V + P A+   AHHMLLFGC+ P ST+  + C +        I++ WA++A     P   G  VGGKS   YFVLQVHY      +DK    +G+ + ++ +    + GI+L  S    I P    VN D++C Y      +  A+R H H LG+ +SG++V    G+  LIG+ +PQ PQ FY     ++I PGDI+  RCLF   GK + T IG T  DEMCN YIM    +    +S+  C       L++NIP  +    P +P                P K  +    K  +    D DV L+ D +W  VN K+G+VSG+++          ++++ HRG H W E SF ++ VYQ+    PI + TI+ VDP +  VL+ A + +F++PHG+T  +DG Y W+TDVA HQV +     +      TP +VLGK F PG D  HFC+P+ VAVD   G  FV+DGYCN+R++ F PNG +I +W  +            I HS+T+  D         + VADREN +I  F  +    + +  H      +F  S +  G+ Y    +  YG ++   ++G    F+             +F  PHD+  AD+G  ++V + H   V KF
Sbjct:   60 LDIRMPGVTPTESDTYLCKSYRLPVDDE-AYVVDFRPHASMDTAHHMLLFGCNMPSSTDDYWDCSAGTCTDKSSIMYAWAKNAPPTKLPEGVGFRVGGKSGNRYFVLQVHYGDVKAFQDKHKDCTGVTVRITPEKQPLIAGIYLSMSVDTVIPPGVDAVNSDIACLYN-RPAIHPFAYRVHTHQLGQVVSGFRV--RHGKWTLIGRQSPQLPQAFYPVEHPLEISPGDIIATRCLFTGKGKTTPTYIGGTAKDEMCNLYIMYYM-DAAHASSYMTCVQTGEPKLFQNIPEIANVPIPVSPDMMMMMGHGHHHEEAEPEKNTALQQPKREEEEVLDQDVHLEEDTDWPGVNLKVGQVSGLALDPKN------NLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQESTILVVDPNTSKVLKSAGKNLFFLPHGLTIDRDGNY-WVTDVALHQVFKLGAEKE------TPLLVLGKAFQPGSDRKHFCQPTDVAVDPITGNFFVSDGYCNSRIMQFSPNGMFIMQWGDETSSTIPKPGQFRIPHSLTMVPDHGQ------LCVADRENGRIQCFHAETGKFVKQIKHREFGREVFAVSYAPGGVLYAVNGKPYYGDSA--PVQGFMLNFSNGEILDTFIPARKNFEMPHDIAAADDGT-VYVGDAHANAVWKF 702          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y+C S+ +P  +E +Y+V + P A+   AHHMLLFGC+ P ST+  + C +        I++ WA++A     P   G  VGGKS   YFVLQVHY      +DK    +G+ + ++ +    + GI+L  S    I P    VN D++C Y      +  A+R H H LG+ +SG++V    G+  LIG+ +PQ PQ FY     ++I PGDI+  RCLF   GK + T IG T  DEMCN YIM    +    +S+  C       L++NIP
Sbjct:   60 LDIRMPGVTPTESDTYLCKSYRLPVDDE-AYVVDFRPHASMDTAHHMLLFGCNMPSSTDDYWDCSAGTCTDKSSIMYAWAKNAPPTKLPEGVGFRVGGKSGNRYFVLQVHYGDVKAFQDKHKDCTGVTVRITPEKQPLIAGIYLSMSVDTVIPPGVDAVNSDIACLYN-RPAIHPFAYRVHTHQLGQVVSGFRV--RHGKWTLIGRQSPQLPQAFYPVEHPLEISPGDIIATRCLFTGKGKTTPTYIGGTAKDEMCNLYIMYYM-DAAHASSYMTCVQTGEPKLFQNIP 343          

Query: 1085 LKMDKNWK-VNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKD-VYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDS-RGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDG---IIKFTH------IFRKSLSIYGIKYNPKNRLIYGITSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKF 2017
            L+ D +W  VN K+G+VSG+++          ++++ HRG H W E SF ++ VYQ+    PI + TI+ VDP +  VL+ A + +F++PHG+T  +DG Y W+TDVA HQV +     +      TP +VLGK F PG D  HFC+P+ VAVD   G  FV+DGYCN+R++ F PNG +I +W  +            I HS+T+  D         + VADREN +I  F  +    + +  H      +F  S +  G+ Y    +  YG ++   ++G    F+             +F  PHD+  AD+G  ++V + H   V KF
Sbjct:  501 LEEDTDWPGVNLKVGQVSGLALDPKN------NLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQESTILVVDPNTSKVLKSAGKNLFFLPHGLTIDRDGNY-WVTDVALHQVFKLGAEKE------TPLLVLGKAFQPGSDRKHFCQPTDVAVDPITGNFFVSDGYCNSRIMQFSPNGMFIMQWGDETSSTIPKPGQFRIPHSLTMVPDHGQ------LCVADRENGRIQCFHAETGKFVKQIKHREFGREVFAVSYAPGGVLYAVNGKPYYGDSA--PVQGFMLNFSNGEILDTFIPARKNFEMPHDIAAADDGT-VYVGDAHANAVWKF 809          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y+C S+ +P  +E +Y+V + P A+   AHHMLLFGC+ P ST+  + C +        I++ WA++A     P   G  VGGKS   YFVLQVHY      +DK    +G+ + ++ +    + GI+L  S    I P    VN D++C Y      +  A+R H H LG+ +SG++V    G+  LIG+ +PQ PQ FY     ++I PGDI+  RCLF   GK + T IG T  DEMCN YIM    +    +S+  C       L++NIP
Sbjct:   60 LDIRMPGVTPTESDTYLCKSYRLPVDDE-AYVVDFRPHASMDTAHHMLLFGCNMPSSTDDYWDCSAGTCTDKSSIMYAWAKNAPPTKLPEGVGFRVGGKSGNRYFVLQVHYGDVKAFQDKHKDCTGVTVRITPEKQPLIAGIYLSMSVDTVIPPGVDAVNSDIACLYN-RPAIHPFAYRVHTHQLGQVVSGFRV--RHGKWTLIGRQSPQLPQAFYPVEHPLEISPGDIIATRCLFTGKGKTTPTYIGGTAKDEMCNLYIMYYM-DAAHASSYMTCVQTGEPKLFQNIP 343          

Query: 1085 LKMDKNWK-VNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKD-VYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDS-RGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDG---IIKFTH------IFRKSLSIYGIKYNPKNRLIYGITSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKF 2017
            L+ D +W  VN K+G+VSG+++          ++++ HRG H W E SF ++ VYQ+    PI + TI+ VDP +  VL+ A + +F++PHG+T  +DG Y W+TDVA HQV +     +      TP +VLGK F PG D  HFC+P+ VAVD   G  FV+DGYCN+R++ F PNG +I +W  +            I HS+T+  D         + VADREN +I  F  +    + +  H      +F  S +  G+ Y    +  YG ++   ++G    F+             +F  PHD+  AD+G  ++V + H   V KF
Sbjct:  501 LEEDTDWPGVNLKVGQVSGLALDPKN------NLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQESTILVVDPNTSKVLKSAGKNLFFLPHGLTIDRDGNY-WVTDVALHQVFKLGAEKE------TPLLVLGKAFQPGSDRKHFCQPTDVAVDPITGNFFVSDGYCNSRIMQFSPNGMFIMQWGDETSSTIPKPGQFRIPHSLTMVPDHGQ------LCVADRENGRIQCFHAETGKFVKQIKHREFGREVFAVSYAPGGVLYAVNGKPYYGDSA--PVQGFMLNFSNGEILDTFIPARKNFEMPHDIAAADDGT-VYVGDAHANAVWKF 809          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y+C S+ +P  +E +Y+V + P A+   AHHMLLFGC+ P ST+  + C +        I++ WA++A     P   G  VGGKS   YFVLQVHY      + K  L           + GI+L  S    I P    VN D++C Y      +  A+R H H LG+ +SG++V    G+  LIG+ +PQ PQ FY     ++I PGDI+  RCLF   GK + T IG T  DEMCN YIM    +    +S+  C       L++NIP
Sbjct:   60 LDIRMPGVTPTESDTYLCKSYRLPVDDE-AYVVDFRPHASMDTAHHMLLFGCNMPSSTDDYWDCSAGTCTDKSSIMYAWAKNAPPTKLPEGVGFRVGGKSGNRYFVLQVHYGDVKAFQGKQPL-----------IAGIYLSMSVDTVIPPGV-DVNSDIACLYN-RPAIHPFAYRVHTHQLGQVVSGFRV--RHGKWTLIGRQSPQLPQAFYPVEHPLEISPGDIIATRCLFTGKGKTTPTYIGGTAKDEMCNLYIMYYM-DAAHASSYMTCVQTGEPKLFQNIP 327          

Query: 1085 LKMDKNWK-VNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKD-VYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDS-RGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDG---IIKFTH------IFRKSLSIYGIKYNPKNRLIYGITSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKF 2017
            L+ D +W  VN K+G+VSG+++          ++++ HRG H W E SF ++ VYQ+    PI + TI+ VDP +  VL+ A + +F++PHG+T  +DG Y W+TDVA HQV +     +      TP +VLGK F PG D  HFC+P+ VAVD   G  FV+DGYCN+R++ F PNG +I +W  +            I HS+T+  D         + VADREN +I  F  +    + +  H      +F  S +  G+ Y    +  YG ++   ++G    F+             +F  PHD+  AD+G  ++V + H   V KF
Sbjct:  485 LEEDTDWPGVNLKVGQVSGLALDPKN------NLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQESTILVVDPNTSKVLKSAGKNLFFLPHGLTIDRDGNY-WVTDVALHQVFKLGAEKE------TPLLVLGKAFQPGSDRKHFCQPTDVAVDPITGNFFVSDGYCNSRIMQFSPNGMFIMQWGDETSSTIPKPGQFRIPHSLTMVPDHGQ------LCVADRENGRIQCFHAETGKFVKQIKHREFGREVFAVSYAPGGVLYAVNGKPYYGDSA--PVQGFMLNFSNGEILDTFIPARKNFEMPHDIAAADDGT-VYVGDAHANAVWKF 793          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y+C S+ +P  +E +Y+V + P A+   AHHMLLFGC+ P ST+  + C +        I++ WA++A     P   G  VGGKS   YFVLQVHY       DK      +  +P   + GI+L  S    I P    VN D++C Y      +  A+R H H LG+ +SG++V    G+  LIG+ +PQ PQ FY     ++I PGDI+  RCLF   GK + T IG T  DEMCN YIM    +    +S+  C       L++NIP
Sbjct:   46 LDIRMPGVTPTESDTYLCKSYRLPVDDE-AYVVDFRPHASMDTAHHMLLFGCNMPSSTDDYWDCSAGTCTDKSSIMYAWAKNAPPTKLPEGVGFRVGGKSGNRYFVLQVHY------GDKY-CCFYVCRQP--LIAGIYLSMSVDTVIPPGV-DVNSDIACLYN-RPAIHPFAYRVHTHQLGQVVSGFRV--RHGKWTLIGRQSPQLPQAFYPVEHPLEISPGDIIATRCLFTGKGKTTPTYIGGTAKDEMCNLYIMYYM-DAAHASSYMTCVQTGEPKLFQNIP 315          

Query: 1085 LKMDKNWK-VNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKD-VYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDS-RGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDG---IIKFTH------IFRKSLSIYGIKYNPKNRLIYGITSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKF 2017
            L+ D +W  VN K+G+VSG+++          ++++ HRG H W E SF ++ VYQ+    PI + TI+ VDP +  VL+ A + +F++PHG+T  +DG Y W+TDVA HQV +     +      TP +VLGK F PG D  HFC+P+ VAVD   G  FV+DGYCN+R++ F PNG +I +W  +            I HS+T+  D         + VADREN +I  F  +    + +  H      +F  S +  G+ Y    +  YG ++   ++G    F+             +F  PHD+  AD+G  ++V + H   V KF
Sbjct:  472 LEEDTDWPGVNLKVGQVSGLALDPKN------NLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQESTILVVDPNTSKVLKSAGKNLFFLPHGLTIDRDGNY-WVTDVALHQVFKLGAEKE------TPLLVLGKAFQPGSDRKHFCQPTDVAVDPITGNFFVSDGYCNSRIMQFSPNGMFIMQWGDETSSTIPKPGQFRIPHSLTMVPDHGQ------LCVADRENGRIQCFHAETGKFVKQIKHREFGREVFAVSYAPGGVLYAVNGKPYYGDSA--PVQGFMLNFSNGEILDTFIPARKNFEMPHDIAAADDGT-VYVGDAHANAVWKF 780          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYNFDIDVL----------KMDKNWKVNKKL---------GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVD-SRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSD---GD---IRGSSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQ 2053
            L ++MPGV    +D Y C S  +P  +E ++++ ++P A+    HHMLLFGC+ P ST   + C          IL+ WAR+A     P   G  VGG++   YFVLQVHY   +   D     SG+ L L+  P   + G++L+ S    I P  + VN D+SC YK     +  A+R H H LG+ +SGY+V   +GQ  LIG+ +PQ PQ FY     V +  GDIL ARC+F   G+   T IG T  DEMCN YIM   +      SF  C  N   D+++ IP  +    P       I     +  N +   L            ++++ V + L         G+VSGV+ L +K      ++++ HRG H W   SF  K VYQ+    PI + TI+ +DP    +L+ + + +FY+PHG++   DG Y W+TDVA HQV +   R       + P +VLG+   PG D NHFC+P+ VAV+ S G VFV+DGYCN+R+V F P+G +I +W  +            + HS+ +          N + VADREN +I  F  D       I   S   +++ I Y P    ++ +      GD   ++G  F  N +S ++    KP      F  PHD+  +++G  +++ + H   V KF +        H+
Sbjct:   63 LDIRMPGVTPKESDTYFCMSMRLPV-DEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSLHLTRVPQPLIAGMYLMMSVNTVIPPGEKVVNSDISCHYK-MYPMHVFAYRVHTHHLGKVVSGYRV--RNGQWTLIGRQSPQLPQAFYPVEHPVDVAFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME-AKHAVSFMTCTQNVAPDMFRTIPEEANIPIPVKSDMVMIHGHHKETENKEKSALIQQPKQGEEEAFEQDFHVEEALEWPGVYLLPGQVSGVA-LDSKN-----NLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNKAEILQSSGKNLFYLPHGLSIDTDGNY-WVTDVALHQVFKLEPRS-----KEGPLLVLGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPKPGQFSVPHSLALVPH------LNQLCVADRENGRIQCFKTDTKEFVREIKHASFGRNVFAISYIPG--FLFAVNGKPYFGDQEPVQG--FVMNFSSGEIIDVFKP--VRKHFDMPHDIVASEDGT-VYIGDAHTNTVWKFTLTESRLEVEHR 715          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIM--MVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y C S  +P  +E ++++ ++P A+    HHMLLFGC+ P ST   + C          IL+ WAR+A     P   G  VGG++   YFVLQVHY   +   D     SG+ L L+  P   + G++L+ S    I P  + VN D+SC YK     +  A+R H H LG+ +SGY+V   +GQ  LIG+ +PQ PQ FY     V +  GDIL ARC+F   G+   T IG T  DEMCN YIM  M  K+     SF  C  N   D+++ IP
Sbjct:   63 LDIRMPGVTPKESDTYFCMSMRLPV-DEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSLHLTRVPQPLIAGMYLMMSVNTVIPPGEKVVNSDISCHYK-MYPMHVFAYRVHTHHLGKVVSGYRV--RNGQWTLIGRQSPQLPQAFYPVEHPVDVAFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKHA---VSFMTCTQNVAPDMFRTIP 346          

Query: 1124 GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVD-SRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSD---GDIRG-SSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQ 2053
            G+VSGV+ L +K      ++++ HRG H W   SF  K VYQ+    PI + TI+ +DP    +L+ + + +FY+PHG++   DG Y W+TDVA HQV +   R       + P +VLG+   PG D NHFC+P+ VAV+ S G VFV+DGYCN+R+V F P+G +I +W  +            + HS+ +          N + VADREN +I  F  D       I   S   +++ I Y P    ++ +      GD      F  N +S ++    KP      F  PHD+  +++G  +++ + H   V KF +        H+
Sbjct:  515 GQVSGVA-LDSKN-----NLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNKAEILQSSGKNLFYLPHGLSIDTDGNY-WVTDVALHQVFKLEPRS-----KEGPLLVLGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPKPGQFSVPHSLALVP------HLNQLCVADRENGRIQCFKTDTKEFVREIKHASFGRNVFAISYIPG--FLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKP--VRKHFDMPHDIVASEDGT-VYIGDAHTNTVWKFTLTESRLEVEHR 821          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIM--MVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y C S  +P  +E ++++ ++P A+    HHMLLFGC+ P ST   + C          IL+ WAR+A     P   G  VGG++   YFVLQVHY   +   D     SG+ L L+  P   + G++L+ S    I P  + VN D+SC YK     +  A+R H H LG+ +SGY+V   +GQ  LIG+ +PQ PQ FY     V +  GDIL ARC+F   G+   T IG T  DEMCN YIM  M  K+     SF  C  N   D+++ IP
Sbjct:   63 LDIRMPGVTPKESDTYFCMSMRLPV-DEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSLHLTRVPQPLIAGMYLMMSVNTVIPPGEKVVNSDISCHYK-MYPMHVFAYRVHTHHLGKVVSGYRV--RNGQWTLIGRQSPQLPQAFYPVEHPVDVAFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKHA---VSFMTCTQNVAPDMFRTIP 346          

Query: 1124 GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVD-SRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSD---GDIRG-SSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQ 2053
            G+VSGV+ L +K      ++++ HRG H W   SF  K VYQ+    PI + TI+ +DP    +L+ + + +FY+PHG++   DG Y W+TDVA HQV +   R       + P +VLG+   PG D NHFC+P+ VAV+ S G VFV+DGYCN+R+V F P+G +I +W  +            + HS+ +          N + VADREN +I  F  D       I   S   +++ I Y P    ++ +      GD      F  N +S ++    KP      F  PHD+  +++G  +++ + H   V KF +        H+
Sbjct:  515 GQVSGVA-LDSKN-----NLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNKAEILQSSGKNLFYLPHGLSIDTDGNY-WVTDVALHQVFKLEPRS-----KEGPLLVLGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPKPGQFSVPHSLALVP------HLNQLCVADRENGRIQCFKTDTKEFVREIKHASFGRNVFAISYIPG--FLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKP--VRKHFDMPHDIVASEDGT-VYIGDAHTNTVWKFTLTESRLEVEHR 821          

Query:  137 EKLKLQMPGVLAMNNDE-YICSSFPVPNHNENSYIVSYEPL---ANSSIAHHMLLFGCSSPFSTEPSF--PCRSICE----NSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTI---EDKSGLLLELSSKPPDYVVGIF---LLFSYYGKIQPQTRKVNLDVSCRYKGNSEA------YTLAFRTHAHALGRSISGYKVSLNDGQ-IELIGKGN---PQWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYI 907
            + + ++ P +L  +N+  Y C    +P      +I+ YE +    N ++ HHM +F C++     P F  PC S  +    N    +L  WA  AK+F+YP   G+  GG  +  +  L+VHY  P  I   +D SG+ L  ++    Y  GI    L+++    I PQ     L   C  K    A      +  A + H H  GR +    V   DGQ  +++ + N   P + +       V + PGD+L+  C +++  K   T  G   ++EMC  Y+
Sbjct:  216 QTMDIRAPDILIPDNETTYWCYITELPPRFPRHHIIMYEAIVTEGNEALVHHMEVFQCAAESEDFPQFNGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPKEAGVPFGGPGSSPFLRLEVHYHNPRKIQGRQDSSGIRLHYTATLRRYDAGIMELGLVYTPLMAIPPQETAFVLTGYCTDKCTQMALQDSGIHIFASQLHTHLTGRKV--VTVLARDGQERKVVNRDNHYSPHFQEIRMLKKVVTVYPGDVLITSCTYNTENKTLATVGGFGILEEMCVNYV 496          

Query:  164 VLAMNNDEYICSSFPVPNHNENSYIVSYEPL---ANSSIAHHMLLFGCSSP----------FSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHY---LKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQ--PQTRKVNLDVS-CRYKG--------NSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKG-----NPQWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFY-----------------IMMVTKNTGEENS 943
            ++  ++  Y C+  P+P  ++  +I  +EP+    N ++ HH+L++ C +           + ++P+F   S+C  SH  ++ GWA    S+ +P + G+++G   +  +  L++HY        I D SG+ L  +S    Y +G+  L      I   P   +  L    C+            S+ Y  A   H H  GRS+   +   N  Q++++ K      N Q  +       V IKPGD L+  C + +  +D +T  G++ ++EMC  +                 I+ VT   GEE S
Sbjct:  201 IIPEDDTTYACTFLPLPIVSKKHHIYKFEPILVERNETMVHHVLVYACGNSSVLPTGIGECYGSDPAF---SLC--SH--VIAGWAVGGLSYQFPDDVGISIGTPFDPQWIRLEIHYSNFQNLPGIRDTSGMRLFYTSHLRKYDMGVLQLGISVFPIHFIPPGAEAFLSYGLCKTDKFEELNGAPVSDIYISACLLHTHLAGRSLQALQYR-NGTQLQVVCKDFSYDFNLQESRDL--PHPVVIKPGDELLIECHYQTLDRDFMTFGGASTINEMCLIFFFYYPRINISSCMGYPDIIYVTNELGEEAS 499          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNP----------------PSKTIS---AKTLQNYNFDIDV-LKMDKNWK-VNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKD-VYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDS-RGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDG---IIKFTH------IFRKSLSIYGIKYNPKNRLIYGITSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKF 2017
            L ++MPGV    +D Y+C S+ +P  +E +Y+V + P AN   AHHMLLFGC+ P ST+  + C +        I++ WA++A     P   G  VGGKS   YFVLQVHY      +DK    +G+ + ++ +    + GI+L  S    I P    VN D++C Y      +  A+R H H LG+ +SG++V    G+  LIG+ +PQ PQ FY     V+I PGDI+  RCLF   G+ S T IG T  DEMCN YIM    +     S+  C       L++NIP  +    P +P                P K       K  +    D DV L+ D +W  VN K+G+VSG+++          ++ + HRG H W E SF ++ VYQ+    PI + TI+ VDP S  VL+   + +F++PHG+T  +DG Y W+TDVA HQV +     +      TP +VLG+ F PG D  HFC+P+ VAVD   G  FVADGYCN+R++ F PNG +I +W  +            I HS+T+  D+        + VADREN +I  F  +    + +  H      +F  S +  G+ Y    +  YG ++   ++G    F+             +F  PHD+  AD+G  ++V + H   V KF
Sbjct:   60 LDIRMPGVTPTESDTYLCKSYRLPVDDE-AYVVDFRPHANMDTAHHMLLFGCNIPSSTDDYWDCSAGTCMDKSSIMYAWAKNAPPTKLPEGVGFRVGGKSGSRYFVLQVHYGNVKAFQDKHKDCTGVTVRVTPEKQPQIAGIYLSMSVDTVIPPGEEAVNSDIACLYN-RPTIHPFAYRVHTHQLGQVVSGFRV--RHGKWSLIGRQSPQLPQAFYPVEHPVEISPGDIIATRCLFTGKGRTSATYIGGTSNDEMCNLYIMYYM-DAAHATSYMTCVQTGEPKLFQNIPEIANVPIPVSPDMMMMMGHGHHHTEAEPEKNTGLQQPKREEEEVLDQDVHLEEDTDWPGVNLKVGQVSGLALDPKN------NLAIFHRGDHVWDENSFDRNFVYQQRGIGPIQESTILVVDPSSSKVLKSTGKNLFFLPHGLTIDRDGNY-WVTDVALHQVFKLGAGKE------TPLLVLGRAFQPGSDRKHFCQPTDVAVDPITGNFFVADGYCNSRIMQFSPNGMFIMQWGEETSSNVPRPGQFRIPHSLTMVPDQGQ------LCVADRENGRIQCFHAETGNFVKQIKHQEFGREVFAVSYAPGGVLYAVNGKPYYGYSA--PVQGFMLNFSNGDILDTFIPARKNFDMPHDIAAADDGT-VYVGDAHANAVWKF 702          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNP-----------------PSKTISA----KTLQNYNFDIDV-LKMDKNWK-VNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKD-VYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDS-RGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGY---DGIIKFTH------IFRKSLSIYGIKYNPKNRLIYGITSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKF 2017
            L ++MPGV    +D Y+C S+ +P  +E +Y+V Y P AN   AHHMLLFGC+ P ST+  + C +   N    I++ WA++A     P   G  VGGKS   YFVLQVHY      +DK    +G+ + ++ +    + GI+L  S    + P    VN D++C Y      +  A+R H H LG+ +SG++V    G+  LIG+ +PQ PQ FY     ++I PGDI+  RCLF   G+ S T IG T  DEMCN YIM    +     S+  C       L++NIP  +    P +P                  ++T +A    K  +    + DV L+ D +W  VN K+G+VSG+++          ++++ HRG H W E SF ++ VYQ+    PI + TI+ VDP +  VL+   + +F++PHG+T  +DG Y W+TDVA HQV +     +      TP +VLG+ F PG D  HFC+P+ VAVD   G  FVADGYCN+R++ F PNG +I +W  +            I HS+T+  D+        + VADREN +I  F     + + +  H      +F  S +  G+ Y    +  YG ++   ++G    F+             +F  PHD+   D+G  ++V + H   V KF
Sbjct:   62 LDIRMPGVTPTESDTYLCKSYRLPVDDE-AYVVDYRPHANMDTAHHMLLFGCNVPSSTDDYWDCSAGTCNDKSSIMYAWAKNAPPTKLPEGVGFQVGGKSGSRYFVLQVHYGDVKAFQDKHKDCTGVTVRITPEKQPLIAGIYLSMSLNTVVPPGQEVVNSDIACLYN-RPTIHPFAYRVHTHQLGQVVSGFRV--RHGKWTLIGRQSPQLPQAFYPVEHPLEISPGDIIATRCLFTGKGRMSATYIGGTAKDEMCNLYIMYYM-DAAHATSYMTCVQTGNPKLFENIPEIANVPIPVSPDMMMMMMMGHGHHHTEAEAETNTALQQPKREEEEVLNQDVHLEEDTDWPGVNLKVGQVSGLALDPKN------NLVIFHRGDHVWDENSFDRNFVYQQRGIGPIQESTILVVDPNTSKVLKSTGQNLFFLPHGLTIDRDGNY-WVTDVALHQVFKVGAEKE------TPLLVLGRAFQPGSDRKHFCQPTDVAVDPITGNFFVADGYCNSRIMQFSPNGMFIMQWGEETSSNLPRPGQFRIPHSLTMISDQGQ------LCVADRENGRIQCFHAKTGEFVKQIKHQEFGREVFAVSYAPGGVLYAVNGKPYYGDST--PVQGFMLNFSNGDILDTFIPARKNFEMPHDIAAGDDGT-VYVGDAHANAVWKF 706          

Query:  137 EKLKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICE-NSHEKILFGWARDAKSFHYPSNTGMAVGGKSN-INYFVLQVHYLKP--TTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECG--GNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDKNWKVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKDVYQEDLD-SPISDYTIVEVDPVSGN---VLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGII-------KFTHIFRKSLSIYGIKYNPKNRLIYGITSDG--DIRGSS------FTFNTTS----SQMKPWNTDYSFRAPHDLCLADNGKFIFVAEL 1993
            +K  +QM G      D+Y+  S          Y+V++EP+A++   HHMLL+GC+ P S +  +     C       IL+ WAR+A +   P +   +VG + + I YFVLQVHY +P    + D SG+ + +S K P  +  + +LF     I PQ      +++C ++ ++  +  AFRTH HA+GR +S +    +DG    IGK NPQWPQ F    +++ I  GD + A C FDS  K+    +G+  +DEMCNFY MM   +   +N + +      ++     + P    E  P  P  +  + ++     F I    + +N     KLG+V+G++    +Q      +LV  R    W   +F  D Y   LD  PI+D  I+ +   SGN   + R+   G FY+PHGI   KDG +++ TDV  H V ++ + + ++L +   S   G+  +PG D +H+CKP+ +       ++V DGYCN+RVV    NG  I ++    P        +  D   D +  ++ V DREN ++      G +        FT+I+  + S     +    R I G  ++G     G S      + F  T+     QM P      F  PH L +  +G  IFV ++
Sbjct:   33 QKFTIQMIGYSPQKTDDYVAVSIEA----TPGYVVAFEPMAHADRVHHMLLYGCTMPASEQGFWRGMETCGWGGGSYILYAWARNAPNLVLPKDVAFSVGHEQDGIKYFVLQVHYAQPFAGEVHDFSGVTMHISQKKPMNLAAV-MLFVSGTPIPPQLPAFQNNITCMFESSTPIHPFAFRTHTHAMGRLVSAF--FKHDGHWTKIGKRNPQWPQLFEGIPSKLMIGSGDQMSASCRFDSMDKNRTVNMGAMGVDEMCNFY-MMFHYDAKLDNPYPQGAICAKDYPSKMIDYPKDGFELLPSRPELEHHAHQS--KVPFGIVQEAIHENLG-GVKLGQVAGLAFNNEQQ------LLVFQRAGRVWDASTF--DNYNILLDKKPIADPVILVIS-YSGNQTKLERKLGGGQFYLPHGIYVDKDG-FVYTTDVGSHTVAKWKI-EGNELKNIWTS---GELLMPGSDQHHYCKPTGI-TRVEDQLYVTDGYCNSRVVVLDLNGKRIRQFGL--PGEDAGQFNLPHDIVSDSAGRLL-VTDRENGRVQHMTTQGHVIEEFKSTMFTNIYSAA-SHEDYVFMVPGRPIMGHETEGIAVFVGRSGTGLIEYAFGPTTKGKREQMGP-----QFGQPHCLRVCPDGGHIFVGDI 646          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIM--MVTKNTGEENSFSECGGNEFKDLWKNIP 994
            L ++MPGV    +D Y C S  +P  +E ++++ ++P A+    HHMLLFGC+ P ST   + C          IL+ WAR+A     P   G  VGG++   YFVLQVHY   +   D     SG+ L L+  P   + G++L+ S    I P  + VN D+SC YK     +  A+R H H LG+ +SGY+V   +GQ  LIG+ +PQ PQ FY     V +  GDIL ARC+F   G+  VT IG T  DEMCN YIM  M  K+     SF  C  N   D+++ IP
Sbjct:   59 LDIRMPGVTPKQSDTYFCMSVRLP-MDEEAFVIDFKPRASMDTVHHMLLFGCNMPASTGNYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPPGGKVVNSDISCHYK-KYPMHVFAYRVHTHHLGKVVSGYRV--RNGQWTLIGRQSPQLPQAFYPVEHPVDVSFGDILAARCVFTGEGRTEVTHIGGTSSDEMCNLYIMYYMEAKHA---VSFMTCTQNVAPDIFRTIP 342          

Query: 1124 GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVD-SRGYVFVADGYCNNRVVCFYPNGTYIEEW------QSQDP--MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITS------DGDIRGSSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQH 2056
            G+VSGV+  L  Q  L    ++ HRG H W   SF  K VYQ+    PI + TI+ +DP +  VL+ + + +FY+PHG++  KDG Y W+TDVA HQV + + +       + P + LG+   PG D NHFC+P+ VAVD   G ++V+DGYCN+R+V F P+G +I +W       S  P    + HS+ +            + VADREN +I  F  D       I   S   +++ I Y P   L++ +           ++G  F  N +S ++    KP      F  PHD+  +++G  ++V + H   V KF     +ST+  +H
Sbjct:  512 GQVSGVA--LDPQNNL----VIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNY-WVTDVALHQVFKLDPKS-----KEGPLLTLGRSMQPGSDQNHFCQPTDVAVDPDTGTIYVSDGYCNSRLVQFSPSGKFITQWGEASLESSPKPGQFRVPHSLALVP------PLGQLCVADRENGRIQCFKTDTKEFVREIKHPSFGRNVFAISYIPG--LLFAVNGKPYFEDQEPVQG--FVMNFSSGEIIDVFKP--VRKHFDMPHDIAASEDGT-VYVGDAHTNTVWKF-----TSTEKMEH 814          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPS 997
            L ++MPGV    +D Y C S  +P  +E ++++ ++P A+    HHMLLFGC+ P ST   + C          IL+ WAR+A     P   G  VGG++   YFVLQVHY   +   D     SG+ + L+  P   + G++L+ S    I P  + VN D+SC+YK     +  A+R H H LG+ +SGY+V   +GQ  LIG+ NPQ PQ FY     V +  GDIL ARC+F   G+   T IG T  DEMCN YIM   +      SF  C  N   D+++ IP+
Sbjct:   64 LDIRMPGVTPKESDTYFCMSMRLPV-DEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNHKDCSGVSVHLTRVPQPLIAGMYLMMSVDTVIPPGEKVVNADISCQYK-MYPMHVFAYRVHTHHLGKVVSGYRV--RNGQWTLIGRQNPQLPQAFYPVEHPVDVTFGDILAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYME-AKYALSFMTCTKNVAPDMFRTIPA 348          

Query: 1124 GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVD-SRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDP--------MFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSD---GDIRG-SSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAK 2032
            G+VSGV+ L +K      ++++ HRG H W   SF  K VYQ+    PI + TI+ +DP +  +L+ + + +FY+PHG++   DG Y W+TDVA HQV + +         + P ++LG+   PG D NHFC+P+ VAV+ S G VFV+DGYCN+R+V F P+G ++ +W  +            + HS+ +          + + VADREN +I  F  D       I   S   +++ I Y P    ++ +      GD      F  N +S ++    KP      F  PHD+  +++G  +++ + H   V KF +  K
Sbjct:  515 GQVSGVA-LDSKN-----NLVIFHRGDHVWDGNSFDSKFVYQQRGLGPIEEDTILVIDPNNAEILQSSGKNLFYLPHGLSIDTDGNY-WVTDVALHQVFKLDPHS-----KEGPLLILGRSMQPGSDQNHFCQPTDVAVEPSTGAVFVSDGYCNSRIVQFSPSGKFVTQWGEESSGSSPRPGQFSVPHSLALVP------HLDQLCVADRENGRIQCFKTDTKEFVREIKHASFGRNVFAISYIPG--FLFAVNGKPYFGDQEPVQGFVMNFSSGEIIDVFKP--VRKHFDMPHDIVASEDGT-VYIGDAHTNTVWKFTLTEK 814          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKN--IPSY-SMEFDPPNPPSKTISAKTLQNYNFDID----------VLKMDKNWK--VNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF--IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDPMF------------IVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFT-HIFRKSLSIYGIKYNPK-NRLIYGITSDG----DIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQHSVGN 2068
            L + MPG+     D Y+C+S PVP   EN YIV +EPLA+  +AHHML+FGC  P     S+ C   C      ILF WA++A   + P + G  +GG SN+ + VLQ+HY  PT   D SG+ L  + +    + GI LL S    I P   +   D+SC++K ++  Y   FRTHAH+LG+ I+GY+    +G   LIGKGNPQWPQ FY    +++I   DIL+ RC+FDST KD+ T IG TH DEMCNFY+M  T   G +  F EC GN   D++KN   PS  S+   PPNP  +  +       +   D           L+  KNW    N KLG+V+GV+           +V + HR    W   +F  + + Y +    PI+  TI+  +P +G ++++  + +FY+PHG++   D   +W+TDVA HQV +FN  ++       PS+ LGK F PG D  HFCKP+ VA+   G  FV+DGYCN+R++ +  +G+ I+ W + D               + H +T+ +D      K  V VADREN +I  F YDG  K   H+      +Y + Y P    L+Y I +D     +  G +  F+T   Q   W     F  PHD+ ++ +GK ++VAE+   +V KF           Q  +GN
Sbjct:   40 LDVTMPGITPKVEDYYVCTSVPVPT-GEN-YIVQFEPLASGDMAHHMLMFGCEQPAENRKSWECGQTCRGK-PNILFAWAKNAPPTNLPEDVGFKIGGSSNVRHIVLQIHYKNPTKEPDASGVRLHYTPERQKNIAGIALLLSTQISIPPHQPETISDISCQFKSSTPIYPFGFRTHAHSLGKVITGYQF---NGTYHLIGKGNPQWPQAFYPVKDKIKISNNDILLGRCVFDSTHKDTYTSIGPTHNDEMCNFYMMYYTDANGGQ-PFYECFGNWRPDMFKNGGFPSQESLTALPPNPALEEEAEHGHSRVDSKADDKLDEEKLTPALEAVKNWPDLGNVKLGQVAGVATDSKG------NVHIFHRADRVWDYSTFDPVNNQYLQRNRGPITQDTILSFNP-NGKLIKQWGKNLFYLPHGLS-IDDQDNIWVTDVAMHQVFKFNKGEEK------PSLTLGKEFEPGNDRYHFCKPTDVAILPTGEFFVSDGYCNHRIIKYAADGSVIKSWGTIDGELAADKYPKPGAFKLPHGLTLAKD------KKQVCVADRENGRIQCFDYDGNFKSQIHLTEFGHKVYAVAYTPHFGGLMYAINADQSNPEENEGFTIKFDTGKLQ-DTWKPQGGFSRPHDVAVSPDGKCVYVAEIGSNRVWKFHSTFDVGIHKSQKKMGN 689          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVP-NHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPS--FPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKS-AQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGN------EFKDLWKNIPSYSMEFDPPN-------------PPSKTISAKTLQNYNFDIDVLKMDKNWKVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKDVYQEDL---DSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDPMFIV-HSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSDGDIRGSSFTFNTTSSQMK-PWNTDYSFRAPHDLCLADNGKFIFVAELHLK-KVIKFEIA---AKSSTKHHQHSVGNNFNQIHDMVKQINPVYIGVLMVAVTVFILICIVTMKYYRRCQXXXXXXXXXX------XXXXDKEGFKPLTQEDDGNDDGNSDPETEEYPALRG 2332
            LK++MPG    ++D Y+CSS  VP N  +  YIV ++ L++ S+AHH+LL+GC  P   EP     C  IC +   KI++ WAR+A     P+NTG  +GG S+I Y V+QVHYL   +  D+S + L+LSS+P  +  GIFL+ +Y G IQP  +   LDVSC+Y G+SE    AFRTHAHAL R+I GY++S +   ++ IG+ +PQW Q FY +   + I+ GD L ARC++D+TG+     IGSTH DEMCNFYIM  T    +      CGG       E + LW+ IP  S+++ P                P K +                 D      ++LG++SGV+     +      V V HRG+  W   +F  D    D    +  I++ T++E+D  SG V+    RG+F+MPH +     G + WITDV  HQV++F+        D  P + +G R  P      FC+P+     S G VFVADGYCN+RVV   P+G++  E+QS D + +V HS+ + E      +  +V VADRE  ++  + ++          K    S+Y + Y+P+ R +Y ++  G       T + TS  ++  W    SF  PH + +A  G  + VAE+ +  ++ KF ++   A+S++  H         +   +V+      +  L++ + + +++  V +   RR  SG     R           +D+EGF+PLTQED       SD E E  P   G
Sbjct:   36 LKVEMPGAAPTHDDSYLCSSTKVPANAGKELYIVGFQALSDMSVAHHVLLYGCQRP-QVEPGKVGDCGGICSSGGSKIVYAWARNAPELRLPANTGFVIGGASSIQYIVIQVHYLHGRSQPDRSAVNLQLSSRPQPFTAGIFLMMAYSGSIQPGAQHATLDVSCKYSGSSEMRPFAFRTHAHALSRAIVGYRLSPDLQDVQEIGRASPQWAQAFYPARPGISIRNGDYLAARCVYDATGETQAHHIGSTHNDEMCNFYIMFSTPAGAKLGDIFSCGGGGPDASTESRRLWRKIPQDSLDYLPSEAPADAFAYAAKATAPRKGVPHPPPAAAAAHKVAAVPDWPRPGGRQLGQISGVAAGPDGR------VFVFHRGARVWGPGAFDPDNRLSDALQSEGAINEDTVLELD-ASGGVISGWGRGVFFMPHSLHIDAQGNF-WITDVGLHQVLKFSP-------DHKPLLTVGVRLTPADGKRGFCQPADAVTSSAGDVFVADGYCNHRVVMLGPDGSFKREFQSADGVLVVPHSLALIE------ADRLVCVADRERARVECWNWETGRSERRFASKEFGDSVYAVAYSPEARQMYAVSGSGH----GLTVDPTSGAVRQAWG---SFTRPHAMAVAAGGAALLVAEIQVPGRLWKFSVSGLTAQSNSPDHFAGQRTVHERALVLVRDSQASLLIGLLLLLPLLVVVLAVALLKLRRRDSGRIGAGRKSLLGGGPGGIRDREGFQPLTQED-------SDEEAETGPGAGG 769          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKN--IPSY-SMEFDPPNPPSKTISAKTLQNYNFDID----------VLKMDKNWK--VNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF--IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDPMF------------IVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFT-HIFRKSLSIYGIKYNPK-NRLIYGITSDG----DIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTK 2044
            L + MPG+     D Y+C+S PVP   EN YIV +EPLA+  +AHHML+FGC  P     S+ C   C      ILF WA++A   + P + G  +GG SN+ + VLQ+HY  PT   D SG+ L  + +    + GI LL S    I P   +   D+SC++K ++  Y   FRTHAH+LG+ I+GY+    +G   LIGKGNPQWPQ FY    +++I   DIL+ RC+FDST KD+ T IG TH DEMCNFY+M  T   G +  F EC GN   D++KN   PS  S+   PPNP  +  +       +   D           L+  KNW    N KLG+V+GV+           +V + HR    W   +F  + + Y +    PI+  TI+  +P +G ++++  + +FY+PHG++   D   +W+TDVA HQV +FN  ++       PS+ LGK F PG D  HFCKP+ VA+   G  FV+DGYCN+R++ +  +G+ I+ W + D               + H +T+ +D      K  V VADREN +I  F YDG  K   H+      +Y + Y P    L+Y I +D     +  G +  F+T   Q   W     F  PHD+ ++ +GK ++VAE+   +V KF     + T+
Sbjct:   40 LDVTMPGITPKVEDYYVCTSVPVPT-GEN-YIVQFEPLASGDMAHHMLMFGCEQPAENRKSWECGQTCRGK-PNILFAWAKNAPPTNLPEDVGFKIGGSSNVRHIVLQIHYKNPTKEPDASGVRLHYTPERQKNIAGIALLLSTQISIPPHQPETISDISCQFKSSTPIYPFGFRTHAHSLGKVITGYQF---NGTYHLIGKGNPQWPQAFYPVKDKIKISNNDILLGRCVFDSTHKDTYTSIGPTHNDEMCNFYMMYYTDANGGQ-PFYECFGNWRPDMFKNGGFPSQESLTALPPNPALEEEAEHGHSRVDSKADDKLDEEKLTPALEAVKNWPDLGNVKLGQVAGVATDSKG------NVHIFHRADRVWDYSTFDPVNNQYLQRNRGPITQDTILSFNP-NGKLIKQWGKNLFYLPHGLS-IDDQDNIWVTDVAMHQVFKFNKGEEK------PSLTLGKEFEPGNDRYHFCKPTDVAILPTGEFFVSDGYCNHRIIKYAADGSVIKSWGTIDGELAADKYPKPGAFKLPHGLTLAKD------KKQVCVADRENGRIQCFDYDGNFKSQIHLTEFGHKVYAVAYTPHFGGLMYAINADQSNPEENEGFTIKFDTGKLQ-DTWKPQGGFSRPHDVAVSPDGKCVYVAEIGSNRVWKFHSTFDAQTQ 681          

Query:   80 MLNLRDLFMFLVVIYLANGE---KLKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFST--EPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLK------PTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDP-------------------------PNPPSKTI--SAKTLQNY-NFDIDVLKMDKNWK------VNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSF-IKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKY-LWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEWQS------------QDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDG-IIKFTHIFRKSLSIYGIKYNP-KNRLIYGI------TSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSST 2041
            ML +  L  F     +A  +    + L+M  V    +D+YIC+S+ +P +   SYIV +EPLAN++ AHH+LLFGCS PF+T  E ++ CR IC    E+ILF WAR+A     P + G  VGG S + + V+Q+HY K      PT   D+SG+ L L+ +   Y  GIFLL +Y   I P T+KV+ D+SC +  +   Y   FR HAH+LGR I+GY V+   GQ ++IGKGNPQWPQ+FY  S +V IKPGD L+ RC ++STG+   T IG T  DEMCNFYIM   K    +  F +C GN    L  N+P  S    P                         PN   K    S   LQ+Y NF  D +  DK         ++  +G+V GV+       K G  V V HRG+  W   SF  ++V+Q+   SPI   TI+  D  S ++LR+  + IFYMPHGIT   D  Y +W+TDV  HQVM F    D       P++ LG +F PG D +HFCKP+ VAV S G  FVADGYCN+R++ F  +GT+I+ + +            +    I HS+T+ ED      K ++ VADREN +I  F ++G   K  H       ++ I+Y P  + L++ +       S   +RG     N T +  + WNT    + PHD+ +  +   ++V EL+  KV +F++  +S +
Sbjct:    8 MLVVLSLVTFATAQSIAPSKVDSMMDLRMKNVSVNKDDQYICTSYRMPVNE--SYIVQFEPLANANTAHHILLFGCSEPFNTQEEGAWSCRMICR-GEEQILFAWARNAPELVLPPDVGFKVGGASKVKHIVVQIHYAKALPSFRPT---DQSGIRLHLTQQRQRYEAGIFLLLAYSLTIPPNTKKVSADISCGFTASGNIYPFGFRAHAHSLGRVITGYHVN-KAGQYKMIGKGNPQWPQSFYPVSNKVVIKPGDKLVGRCTYNSTGRMKTTVIGPTAGDEMCNFYIMYY-KEVSTQIPFPQCVGNNVPSLITNLPPGSDVQLPYNATLEAAAHGHRSHMQGHEDSDVAPNTIDKPTDGSKPGLQHYVNFQSDFMS-DKAMSSSSVSGLDYPIGQVGGVAT----DNKGG--VYVFHRGNRVWDGSSFNFQNVFQQQT-SPIEQETIITYDKDS-HILRKFGKNIFYMPHGITV--DQNYNIWVTDVGLHQVMMFPAGSDQ------PNLTLGVKFQPGSDNSHFCKPTDVAVLSTGEFFVADGYCNSRIMKFSKDGTFIKSFGNGLMTIQADGFPPEGSFDIPHSLTVAED------KGLLCVADRENGRIQCFDFNGNFQKQIHPAEFGPRLFAIEYCPLHDGLLFAVNGPPLDNSQTTVRGFIIDIN-TGTLSETWNTQDGLKNPHDVAVDPHNLRVYVGELNPNKVWRFDMMGESGS 697          

Query:  182 DEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCS-SPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNP------------------------------PSKTISAKTLQNYNFDIDVLKMDKNWKVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKDVYQ--EDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDPMF-------------IVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRK---SLSIYGIKYNPKNR----LIYGITSDG-DIRGSSFTFN-TTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSST 2041
            D YIC+S+ +P   +  YIV +E LAN+S AHH+LLFGCS  P  T P++ C  +C+ S E+I+F WA++A     P + G  VGG S I   VLQ+HY   +   D+SG+ + ++ +   YV GIFL+ SY   I P    V+ DVSC+Y G +E +  A+RTHAH LG  I+GY+    +    +IGKGNPQWPQ FY  + ++ +KPGD ++ARC ++ST +D+ T IG T  DEMCNFY M  T +   E +F +CGG+++ ++   +P+ S    PPNP                               S+        +Y FD      ++ W    +LG+VSGV+       K G +V + HRGS  W   SF  D Y       + I + TI+  D   G ++R     +F+MPHG++   D   +W+TDVA HQ MRF    D       P ++LG+RF P  D NHFCKP+ +A+ S G  F++DGYCN RV+ F  +G +++++ +QD +F             + HSITI ED      KN+V VADREN +I  F ++G  KF+HI +       ++ I+Y P +      + G   DG +     FT +  T   ++ WN      +PHD+ +      ++VAEL  K V KF ++ K+ +
Sbjct:    1 DSYICASYEMPQ--DEVYIVKFEALANASTAHHILLFGCSDGPALTTPTWGCPPLCK-SREQIMFAWAKNAPPTVLPKDVGFRVGGGSTIRNIVLQIHYAHSSPYPDQSGIRVYVTRQKYKYVAGIFLMMSYSITIPPHKSVVHADVSCKYNGKTEIHPFAYRTHAHELGTVITGYQY---NKTYYMIGKGNPQWPQAFYPVTEKITVKPGDNMLARCTYNSTQRDTPTYIGPTGKDEMCNFYTMFYT-DASVETTFGQCGGSQYPEIVDQLPAGSDTRLPPNPLLDEMAGHHHHHPQAQTPPSTGTGNNNRLHQSRPYPGTDYPDYQFDHPANVNNQQWPTGHRLGQVSGVATG-----KNG-NVYIFHRGSRKWEWDSF--DAYNVFTLQTATIPEKTILVYD-KDGTLIRAFGENLFFMPHGLSV-DDNDNIWVTDVALHQAMRFPAGKDK------PDLILGERFKPESDENHFCKPTDIAILSTGEFFISDGYCNGRVMKFSADGKFLKQFGTQD-LFATDDGEPPNGAFDVPHSITIAED------KNLVCVADRENGRIQCFDFEG--KFSHIIKVKEFGSRLFAIEYTPLHDGMLFAVNGPVYDGVETVVQGFTVDIKTGKLLQSWNIPQGLNSPHDVAVNSVDHSVYVAELD-KVVWKFIMSHKAGS 643          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC---RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYN----FDIDVLKMDK-----------------NW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSR-GYVFVADGYCNNRVVCFYPNGTYIEEW-------QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNP-KNRLIYGITSD------GDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTK 2044
            + ++MPGV+   +D Y C + PVP   E +YIV + P A+   AHHMLL+GC +P ST+  + C   +  CE+   KI++ WAR+A     P + G  VGG + I YFVLQ+HY       D     SGL L ++SKP  ++ G++L+ S    I P     N D++C Y  +   Y  AFRTH H LG+ +SGY++   +GQ  LIG+ +PQ PQ FY  S  +++K GD L ARC+F   G+ S T IG T  DEMCNFY+M    N      + +C  +    L+++IP+   E + P P S       +   N     D   L+  K                 +W +V  +LG+VSG+++          ++++ HRG H W   SF  K VYQ+    PI   TI+ VDP  GNVL+ + + +FY+PHGIT  KD  Y W+TDVA HQV +      SK   + P +VLG+ F PG D +HFCKP+ VAVD   G +FV+DGYCN R++ F P G Y+ +W       + + P  I HS+    D      K  + VADREN ++  F  D       I R      +Y + Y P +  LIY +  +        +RG    ++T             F+ PHD+ +  +G  ++V +     VIKF  + K+  +
Sbjct:   60 VDIRMPGVVPSASDSYYCVAVPVPTSWE-AYIVDFVPHASMDTAHHMLLYGCRNPTSTKGYWDCGREQGTCED-EAKIMYAWARNAPPTKLPKDVGFKVGGDTRITYFVLQIHYGDIKNFRDHHKDCSGLTLRMTSKPQPFIAGMYLMMSVDTVIPPGKTVTNADIACTYL-SYPMYPFAFRTHTHRLGKVVSGYRI--RNGQWTLIGRQSPQLPQAFYPVSNDIEVKYGDTLAARCVFTGEGRSSKTRIGGTSNDEMCNFYMMYYMDNK-HSIPYMDCMDHGSSSLFRSIPN---EANVPIPVSPDHMMNMMHGSNQKDGEDGAALQQPKREQEEVLDQGTHLEELADWPEVELQLGQVSGLAVDSDD------NLVIFHRGDHRWEMNSFDNKAVYQQRSLGPIQQSTILVVDPSKGNVLKASGKNMFYLPHGITTDKDNNY-WVTDVALHQVFKL-----SKDGTEKPLLVLGEAFKPGSDKSHFCKPTDVAVDPETGNIFVSDGYCNTRILKFSPEGKYLSDWGAGSLDRRRRVPFQIPHSLAFVPD------KRELLVADRENGRVQCFMADTGEFVKEIKRDEFGGEVYAVSYAPVQGGLIYVVNGESPYGQSAPLRGFVLNYSTKEILDTFAPDTQKFKMPHDIVVTKDGS-VYVGDATSDSVIKFVPSEKAEHR 713          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC---RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPS 997
            + ++MPGV+   +D Y C + PVP   E +YIV + P A+   AHHMLL+GC +P ST+  + C   +  CE+   KI++ WAR+A     P + G  VGG + I YFVLQ+HY       D     SGL L ++SKP  ++ G++L+ S    I P     N D++C Y  +   Y  AFRTH H LG+ +SGY++   +GQ  LIG+ +PQ PQ FY  S  +++K GD L ARC+F   G+ S T IG T  DEMCNFY+M    N      + +C  +    L+++IP+
Sbjct:   60 VDIRMPGVVPSASDSYYCVAVPVPTSWE-AYIVDFVPHASMDTAHHMLLYGCRNPTSTKGYWDCGREQGTCED-EAKIMYAWARNAPPTKLPKDVGFKVGGDTRITYFVLQIHYGDIKNFRDHHKDCSGLTLRMTSKPQPFIAGMYLMMSVDTVIPPGKTVTNADIACTYL-SYPMYPFAFRTHTHRLGKVVSGYRI--RNGQWTLIGRQSPQLPQAFYPVSNDIEVKYGDTLAARCVFTGEGRSSKTRIGGTSNDEMCNFYMMYYMDNK-HSIPYMDCMDHGSSSLFRSIPN 346          

Query: 1100 NW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSR-GYVFVADGYCNNRVVCFYPNGTYIEEW-------QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNP-KNRLIYGITSD------GDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQHSVGNNFNQIHDMVKQ 2101
            +W +V  +LG+VSG+++          ++++ HRG H W   SF  K VYQ+    PI   TI+ VDP  GNVL+ + + +FY+PHGIT  KD  Y W+TDVA HQV +      SK   + P +VLG+ F PG D +HFCKP+ VAVD   G +FV+DGYCN R++ F P G Y+ +W       + + P  I HS+    D      K  + VADREN ++  F  D       I R      +Y + Y P +  LIY +  +        +RG    ++T             F+ PHD+ +  +G  ++V +     VIKF  + K+ T      V  N   IH  + Q
Sbjct:  502 DWPEVELQLGQVSGLAVDSDD------NLVIFHRGDHRWEMNSFDNKAVYQQRSLGPIQQSTILVVDPSKGNVLKASGKNMFYLPHGITTDKDNNY-WVTDVALHQVFKL-----SKDGTEKPLLVLGEAFKPGSDKSHFCKPTDVAVDPETGNIFVSDGYCNTRILKFSPEGKYLSDWGAGSLDRRRRVPFQIPHSLAFVPD------KRELLVADRENGRVQCFMADTGEFVKEIKRDEFGGEVYAVSYAPVQGGLIYVVNGESPYGQSAPLRGFVLNYSTKEILDTFAPDTQKFKMPHDIVVTKDGS-VYVGDATSDSVIKFVPSEKTET-----FVQANLKPIHKPLAQ 830          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC---RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPS 997
            + ++MPGV+   +D Y C + PVP   E +YIV + P A+   AHHMLL+GC +P ST+  + C   +  CE+   KI++ WAR+A     P + G  VGG + I YFVLQ+HY       D     SGL L ++SKP  ++ G++L+ S    I P     N D++C Y  +   Y  AFRTH H LG+ +SGY++   +GQ  LIG+ +PQ PQ FY  S  +++K GD L ARC+F   G+ S T IG T  DEMCNFY+M    N      + +C  +    L+++IP+
Sbjct:   60 VDIRMPGVVPSASDSYYCVAVPVPTSWE-AYIVDFVPHASMDTAHHMLLYGCRNPTSTKGYWDCGREQGTCED-EAKIMYAWARNAPPTKLPKDVGFKVGGDTRITYFVLQIHYGDIKNFRDHHKDCSGLTLRMTSKPQPFIAGMYLMMSVDTVIPPGKTVTNADIACTYL-SYPMYPFAFRTHTHRLGKVVSGYRI--RNGQWTLIGRQSPQLPQAFYPVSNDIEVKYGDTLAARCVFTGEGRSSKTRIGGTSNDEMCNFYMMYYMDNK-HSIPYMDCMDHGSSSLFRSIPN 346          

Query: 1100 NW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSR-GYVFVADGYCNNRVVCFYPNGTYIEEW-------QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNP-KNRLIYGITSD------GDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTK 2044
            +W +V  +LG+VSG+++          ++++ HRG H W   SF  K VYQ+    PI   TI+ VDP  GNVL+ + + +FY+PHGIT  KD  Y W+TDVA HQV +      SK   + P +VLG+ F PG D +HFCKP+ VAVD   G +FV+DGYCN R++ F P G Y+ +W       + + P  I HS+    D      K  + VADREN ++  F  D       I R      +Y + Y P +  LIY +  +        +RG    ++T             F+ PHD+ +  +G  ++V +     VIKF  + K+  +
Sbjct:  502 DWPEVELQLGQVSGLAVDSDD------NLVIFHRGDHRWEMNSFDNKAVYQQRSLGPIQQSTILVVDPSKGNVLKASGKNMFYLPHGITTDKDNNY-WVTDVALHQVFKL-----SKDGTEKPLLVLGEAFKPGSDKSHFCKPTDVAVDPETGNIFVSDGYCNTRILKFSPEGKYLSDWGAGSLDRRRRVPFQIPHSLAFVPD------KRELLVADRENGRVQCFMADTGEFVKEIKRDEFGGEVYAVSYAPVQGGLIYVVNGESPYGQSAPLRGFVLNYSTKEILDTFAPDTQKFKMPHDIVVTKDGS-VYVGDATSDSVIKFVPSEKAEHR 816          

Query:  188 YICSSFPVPNHNENSYIVSYEPL---ANSSIAHHMLLFGCSSPFST----------EPSFP-CRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKP---TTIEDKSGLLLELSSKPPDYVVGIF---LLFSYYGKIQPQTRKVNLDVSCRYKGNSEAY---------TLAFRTHAHALGRSISGYKVSLNDGQIELIGKG-NPQWPQTFYK----SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIM 910
            Y C  + +P+  +  +I+  EPL    + ++ HH+LL+ C S  +            P+ P   + CE     ++F WA   + F YP + GM++G   +  Y ++++H+  P   T + D SGL L  + K   Y  G+    +  S Y  + P       +  C  +   E+            A   HAH  GR+I   +      Q+EL     + Q+   F +    S + QI PGD L+  C++++ G++++T  G +  +EMC  Y++
Sbjct:  232 YWCQMYKMPDVQQKHHIIRIEPLIQKGHENLVHHILLYQCDSSLNESELDLGHNCFHPNMPDSFTTCET----VIFAWAIGGEGFTYPPHVGMSIGTDIDPVYVLMEMHFDNPALQTDVVDSSGLRLFYTPKLRTYDAGVIETGVWVSLYHMLPPGMEDFITEGHCTQECLQESLESEMPSGVSVFAALLHAHLAGRAI---RTRHFRQQVELPPMALDDQFDFNFQEFQPLSPERQILPGDSLITECVYNTKGRNNMTWGGLSTRNEMCLSYLL 499          

Query:  128 ANGEKLKLQMPGV-LAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFG-CSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTI---EDKSGLLLELSSKPPDYVVGIF---LLFSYYGKIQPQTRKVNLDVSCRYKGNSEA------YTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYI 907
            A+ + +++  PG+ +      Y C  + +P +   ++IV YE +  S   +  +  G C S         CR         +L  WA  A+ F+YP + G+ +GG+ +  +  L+VHY  P  I   +D SG+ L  +     +  GI    L+++    I P+     L   C       A      +  A + H H  GR++    V     ++E++ +         + S   Q+  GD L+ +C F++  ++  T  G   M+EMC  Y+
Sbjct:  207 ADVQSIEVLAPGITIPSQETTYWCHIYQLPANMPKNHIVMYESVVTS--GNEAIYSGSCDSKMKPANLNYCR--------HVLAAWALGAEPFYYPMDAGLPIGGEGSSRFLRLEVHYHNPLIISGRQDSSGIRLWYTRSLRRFDAGIMELGLVYTPVMAIPPRQSSFPLSGYCIPACTRTALPQGGIHIFASQLHTHLAGRTVRTVLVR-GGKEVEVVQEDK-------HYSTHYQVLHGDALVTKCTFNTEDRNKPTVGGFGIMEEMCVNYV 462          

Query:  767 QTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYS--MEFDPPNPP----------SKTISAKTLQN-----YNFDIDVLKMDKNWKVNK-KLGEVSGVSILLTKQYKLGYSVLVLHRGSHAW-TERSFI-KDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSR-GYVFVADGYCNNRVVCFYPNGTYIEEWQSQD----------PMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLS--IYGIKYNPKN-RLIYGITS-------DGDI-RGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQ 2053
            Q FY  A+ ++++ GDI+ ARC+F   G    T +G    DEMCN YIM  T +  + N    C       L++ IP+ +      P   P          SKT + KT ++     +  +  VL+ D  W      LG+V+G+++           + V HR    W   RSF  +D + ED   PI++ TI+  DPVSG+++    +G+FY+PHG++   +GK LW+TDVA HQV R           K P + LG+R  PG   +HFCKP+ VAVD R    F++DGYCN R+  F  +GT++ EW ++            + +V  ++      G    + + VADREN ++  F  D   +   I   +    ++ + Y P +  L+Y +          G++ +G    ++T          D     PHD+ +  NG  +FV +    +V KF     S    H+
Sbjct:    1 QAFYPRAEPMEVRLGDIVAARCVFSGLGMSETTYVGMNSDDEMCNLYIMYST-DASQGNPSIRCMKRGEARLFRGIPAIANVPVLMPNRSPEKLAYLTKGISKTGTIKTQRSIDRPSFPRNFHVLEQDTQWHPEGVTLGQVTGLAVDTDDL------IYVFHRADRIWDPRRSFNNRDEFLEDHLGPIAEDTILAFDPVSGHLVHSFGKGMFYLPHGLSIDFEGK-LWVTDVALHQVFRLATGG-----GKEPLLTLGQRMRPGDGASHFCKPTDVAVDPRLRLAFISDGYCNGRIAVFSLDGTFVREWGTEGSKPGEFRIPHALTLVSRVSDDAGNDGGGDSSALCVADRENGRVQCFRADDGTRTRTIEHAAFGGRVFSLAYTPASGGLLYVLNGAPLTGEEGGEMPKGFVLRYDTGDILSTFVPKDERMHMPHDVAVLGNGSAVFVGDTISGRVWKFTPVETSLEAIHR 459          

Query:  188 YICSSFPVPNHNENSYIVSYEPL---ANSSIAHHMLLFGCSSPF---------------STEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIE---DKSGLLLELSSKPPDYVVGIFL--LFSYYGK-IQPQTRKVNLDVSCRYK------GNSEAYTLAFR-THAHALGRSISGYKVSLNDGQIELIGKG---NPQWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMC 895
            Y C  F +P  ++  +++  +P+    N    HH+L++ C +                 ST P   C+++        +  WA   ++F YP+N G ++G   +  + +LQ+HY     +    D SG     + +   Y  G+    +F+Y    I P T +      C  K       NS    LA R  H H  G S+       N  QI  +G+    +  + +T Y +    + PGD ++  C++++ G+++ T  G   MDEMC
Sbjct:   17 YSCKLFQLPKLDKKHHLIKVKPVIQAGNERYVHHLLVYVCLNTLNVSYVGSQAECYKYSSTHPFATCKTV--------MAAWAVGGETFDYPANAGFSLGLDEDPQFLLLQMHYDNAGLVSRANDSSGFRFYYTPELRTYEAGLLETGIFAYSQHFIPPNTARFTSYGICNTKTFYTSNANSTLQVLAVRFLHTHLAGISVQARHFR-NGTQIGNLGRDMGYDFDFQETRYLNKLTSVLPGDQIITECIYNTAGRNTTTAGGLGTMDEMC 277          

Query:  188 YICSSFPVPNHNENSYIVSYEP---LANSSIAHHMLLFGCSSPFST----------EPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTT---IEDKSGLLLELSSKPPDYVVGIF------------------LLFSYYGKIQPQTRKVNLDVSCRY---KGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKG---NPQWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVT--EIGSTHMDEMC 895
            Y C  FPVP  +   +++   P     N +  HH+LL+ CS+  +            P+ P      +    I+ GWA    +F YP   G ++G + +  + +L+ HY  P     + D SGL   ++ +   Y  G+                    + S YG       +V+L   C +   + + E    A   HAH LG ++   +      QI  +G+    +  + +  Y      + PGD L+  C + ST +   T  ++G +  DEMC
Sbjct:  169 YQCEIFPVPKLDRKHHLIKVVPRLQANNEAFVHHILLYTCSASVNASHVGASHECNHPNMP--DSFTHCFGGIMAGWAVGGGTFDYPPEAGFSLGAQGDPQFVMLETHYDNPAQLAGVADSSGLRFYITPELRAYDSGMLEVGVNPQPTHFIPPMTPSFMRSIYGH-----ERVSL-CPCGHTQARQSGEIQVFATILHAHLLGAAMQ-VRHFRQGKQIGHLGRDMGYDFNYQEARYLKELTAVLPGDELITECTYRSTSRSHTTTFKVGLSTQDEMC 437          

Query:  248 EPL---ANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSH--------------EKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKP---TTIEDKSGLLLELSSKPPDYVVGIF---LLFSYYGKIQPQTRKVNLDVSCRYKGNSEAY---------TLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNP---QWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIG--STHMDEMCNFYIMMVTK-NTGEENSFSECGGN 964
            EPL    +  + HH+LL+ C+            +I ++ H              E ILF WA    +F YP + G+++G   +  + +++ HY  P   + I D SGL L  +++   Y  G+    +  S Y  + P          C  +  +EA            A   HAH  GR +   +    D ++ L+ + +     + +     ++  + PGD L   C++++ G+ ++T  G  STH +EMC  Y++   + N     S  E  G 
Sbjct:    3 EPLVKPGHEGMVHHILLYQCALGLH-------EAILQSGHRCYQANMPEEFRSCESILFAWAIGGGAFLYPPHVGLSLGEPGDPVFVLMETHYDNPLQLSGIRDNSGLRLHYTAQLRAYDAGVMETGVWVSLYHMVPPHAPHWVSQGHCTRECLNEALGTERPQGVSVFAVLLHAHLAGRELL-VRHWRGDRELPLLARDSEYDFNFQELHMLPSERLLLPGDHLTTECVYNTEGRVNMTWWGGQSTH-NEMCLAYVLYYPRVNLSRCQSLPEINGQ 270          

Query:  185 EYICSSFPVPNHNENSYIVSYEPL---ANSSIAHHMLLFGCSSPFSTE---PSFPC-RSICENSHEK-----ILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKP-------TTIEDKSGLLLELSSKPPDYVVGIF---LLFSYYGKIQPQTRK------------VNLDVSCRYKGNSEAYTLAFRT--HAHALGRSISGYKVSLNDGQIELIGKG---NPQWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMC 895
             Y+C+   +PN  +  +++  +PL    N+   HHM+++ C +  +      +F C  S+   +H       +L  WA   ++F YP++ G ++G  ++    +L++HY  P       T + D SGL L  +     Y  GI    +L + Y  I P+T              V  + +   +G        F T  H+H  G +I   +   N  QI  +G+    +    +T Y +    + PGD ++  C + +T +   T  G + M+EMC
Sbjct:    7 NYVCNVMQLPNLTKKHHLIKVQPLVQAGNTRFVHHMIVYACETNVNMSYINTTFQCYSSMGATNHPSARCLSVLAAWAVGGETFDYPADAGYSLGMDADPKVVMLEMHYNNPQAASGTHTGVSDSSGLRLYYTPNLRKYDTGILETGILPNIYHFIPPKTTSFTSYGICNTRSFVTANSNDTLQGQVSGTMNVFATMLHSHLAGIAIQ-VRHFRNGNQIGNLGRDMGYDFGLQETRYLNNLTAVLPGDQVVTECTYRTTTRTVTTTGGLSTMNEMC 281          

Query:  155 MPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCR----SIC-ENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHY------LKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKV----SLNDGQIELIGKGNPQWPQTFY--KSAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIM 910
            MP V  + +D Y C++ PV   ++ +YIV Y+P A    AHHMLLFGCS+P S EP + C      +C + S EKI++ W ++A +   P      VG  S++ Y VLQVHY      +K   ++D SG+ +  + + P  +  I LL S  G I P+ +  +LD++C+Y+  +  +  AFR HAH LG  I+GY+V    + ND + +LIGKG+PQ PQ FY  K    +IK GD++  RC F+S  KD  T IG+T  DEMCNFY+M
Sbjct:    1 MPNVHPVKHDSYFCTALPV--ESDETYIVGYDPHAEMHTAHHMLLFGCSTPASNEPHWNCGDMGVGVCGKGSGEKIMYAWGKNAPTLELPEGVAFKVGQASSVKYLVLQVHYGHVDKFVKNPDLKDSSGITIRTTHERPKQLASILLLVSG-GSIPPKQKVAHLDMACKYQNPAVMHPFAFRVHAHTLGTVITGYRVQNAENANDAKWDLIGKGDPQRPQAFYPVKDKHTEIKAGDVVAGRCTFNSMKKDKTTYIGATMKDEMCNFYMM 266          

Query:   98 LFMFLVVIYLANGE----KLKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSI----CENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTI--EDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGK--DSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEF 970
            L + ++ +  A G+    +L ++MPG  A  ND+Y+C+S PV  H +  YIVS+E  A   +AHHM+L GC  P S +  + C  +    C +  E ILF WA++A     P      +G K NINY VLQVHY     +   D SG +L  ++  P Y+ GI+LL+S    I P T++V++D++C+Y+ +   Y  A+RTHAH LGR ISGY+V   D +  L+GKG+PQ PQ FY     V I  GD + ARC FDS G   D    IG+T  DEMCNFY+M     +       EC  N  
Sbjct:    6 LLVSILAVLGAQGDLRYKELSVKMPGAAAKQNDDYLCTSVPV--HADEEYIVSFEAEATEEVAHHMILSGCKIPGSRKKVWGCGLMGGLECASGQE-ILFAWAKNAPPKKLPKGVAFQIGKKFNINYLVLQVHYRHKAKVGQSDHSGFVLHTTTTRPHYIAGIYLLWSGDADIPPDTQEVHVDLACKYQDDHPIYAFAYRTHAHGLGRVISGYRV--QDSKWSLLGKGDPQAPQAFYPIDHPVTISKGDTVAARCTFDSRGHKLDHHVHIGATGADEMCNFYLMYYRDASARPLRQDECNSNRL 304          

Query: 1097 KNWKV--NKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKD-VYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEW---------QSQDPMF---IVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSL--SIYGIKYNPKNRLIYGITSDGDIRGS------SFTFNTTSSQMK---PWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEI 2023
            +NW +   + LG+VS V++ +        +V+V HRGS AW  +SF +D V+QE   +PI ++T+   D  +G ++    R  FYMPHG+T   +    WITDVA HQV ++     S+     P +VLG+   PG D  HFC+P+ VA+++ G  +VADGYCN+RV+ F P G  +E++          S  P+    +VHS+ +      D + + ++VADREN ++             I  K    S+Y + +N  +  +  + +   + G        FT  T+   +    P   ++ F  PHD+  + +   +FV +    +V K  +
Sbjct:  409 ENWPLLGQETLGQVSAVALDMRG------NVVVFHRGSRAWDLKSFDRDNVFQER--TPIREHTVTTFDRKTGKIIGRWGRDRFYMPHGLTIDHEDN-TWITDVALHQVHKYGTDGSSE-----PVLVLGEMLRPGSDDKHFCQPNDVAIETTGVFYVADGYCNSRVMKFSPEGKLLEQYGKAMSARGLGSPPPLGVFDVVHSLAL------DQTHHHLYVADRENGRVQRLDTKKGRFDREITNKEFGASVYAVDFNSHDGGVLHVVNGESVFGGKRIAVQGFTVRTSDGALLGKWPGQGNF-FTQPHDIASSADNNELFVTQTGPNRVWKLTL 722          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCR----SICEN-SHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHY------LKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQ-VQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIM 910
            ++++MP V  + +D Y C++ PV   ++ ++IV YEP A    AHHMLLFGCS+P S E  + C      +C + S E+I++ W R+A   + P      VG  S++ Y VLQVHY      +K   + D SG+ L+ +   P ++  I L  S  G+I P  +  +LD+ C Y   +  +  AFR HAH+LG  I+GY+V   DG+  LIGKG+PQ PQ FY   Q V IK GD L ARC +++  KD +T IG+T  DEMCNFY+M
Sbjct:    8 IEMKMPNVRPLKHDSYFCTAVPV--KSDEAFIVGYEPHAEMHTAHHMLLFGCSTPASKEGFWNCGDMGVGVCASGSPERIMYAWGRNAPKLNLPKGVAFKVGQASSVKYLVLQVHYGHVDKFVKNPKLHDSSGVTLQTTHMRPKFLAAILLQASG-GEIPPHKKAAHLDMGCAYSNKATMHPFAFRVHAHSLGSVITGYRV--RDGKWTLIGKGDPQRPQAFYPIKQEVDIKDGDTLAARCTYNTMKKDRITYIGATMKDEMCNFYMM 270          

Query:  116 VIYLANGEKLKLQMPGVLAMNN-----------DEYICSSFPVPNHNENSYIVSYEPLANS---SIAHHMLLFGCSSPF----------STEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTT---IEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQ-----PQTRKVNLDVSC-----RYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQ--IELIGKGNPQWPQTFYK--SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIM 910
             + L N  K K Q+P  L+  +             Y+C  F  P      +IV Y PL NS      HHML++GC S F           T+ + P  +I   S    +  WA   + F+YP + G+A G      Y VL++HY  P     + D SG+    ++K   +  GI  L++ +  I      P+  +      C     R     +     F    H   + I  +   + DG+   E+I + +  +    ++    +V +KPGD ++  C + +  K+     G    +EMC  +++
Sbjct:  144 TLILLNVHKKKPQLPAQLSHFDLRHNLTIPSRLTSYMCKPFEFPQPASKHHIVKYMPLINSKNLGRVHHMLVYGCHSSFPRSNLSHVGECTDKNMP-PAIQRCSGAAPIAAWAIGGEDFYYPEHVGLAFGDGHGPRYVVLEIHYDNPQNDLGVYDDSGIRFFFTNKTRQFDAGI--LWAGWAPISAMVIPPRQEEWTSIGYCPSNCTRLSSLPDKGINIFAGMEHTHLQGIKVWTRHVRDGKELPEIIREEHYDFNYQEFQVLRNEVHVKPGDDIIQMCKYQTKNKNYPVVGGLGTTEEMCMSFLL 446          

Query:  188 YICSSFPVPNHNENSYIVSYEPLA---NSSIAHHMLLFGCSSPF-----------STEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIE---DKSGLLLELSSKPPDYVVGIFLL---FSYYGKIQPQ----------TRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNP---QWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMC 895
            Y C  F +P   +  +IV ++P+    N+ I HH ++  C   F           + E + P   +       ++  W      F YP + G  +G      YFV++VHY  P  +    D SG+    +     Y  G+  +    + +  I P+           ++ N +VS   K     +  AF  H H  GR+     V  N  ++  I + +     +    + + +V   PGD L+  C++++  +  VT  G    DEMC
Sbjct:  207 YSCHVFTIPKFTKKHHIVRFDPVVQSENAGIVHHFIVMACDKDFPEHLSNDTSECTDEANMPAEVLKCRGRGVLVGAWGVGGGPFVYPDHVGSPLGLDFQGRYFVMEVHYNNPDKLAGKIDNSGVRFFYTDSLRKYDAGVLNVGASVTPWMLIPPKQKEWTTTTYCNKRCNENVSVTQKSRRIKFFSAF-LHTHLAGRATWTKHVR-NGVELPEIARDDNYDFNFQDIQFLNKEVHFLPGDELIHECVYNTMDRTGVTFGGEATNDEMC 473          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRS---ICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDK-----------------NW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSR-GYVFVADGYCNNRVVCFYPNGTYIEEW------QSQDPMF-IVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLS--IYGIKYNPK-NRLIYGITSD-----GDIRGSSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQ 2053
            + L+MPGV   N+D Y+C +FPVP  N++SYIV + P A+ +  HHM+LFGC SP S   S+ C      C++    I++ WAR+A     P + G  VG  S ++YFVLQVHY   +   D     SGL L ++SKP  +V GI+LL S    I P     N DV+C Y  +   Y  AFRTH H LG+ +SGY++   +G+  LIG+ +PQ PQ FY  + ++ ++ GD + ARC+F   G+ S T IG T  DEMCNFY MM   +      F  C  +  ++ +++IP+   E + P   S    +  +   +   D + +DK                 +W + N +LG+VSG+++          ++++ HRG H W   SF  +  YQ     PI    I+ VDP  G +L+ + R +FY+PHGITA +D  Y W+TDVA HQV++  V  D +  D+T  + LG+ F PG D +HFC+P+ VA+D   G VFV+DGYCN R++ F  +G Y+ +W      + Q   F I HS+    D      +  V VADREN +I  F  D       I ++     ++ I Y+P  + LIY +  D       +RG  F  N TS ++     P      F+ PHDL    +G  +FV +   ++V KF     S+ K H+
Sbjct:   51 MDLRMPGVSPSNSDTYLCMAFPVPT-NQDSYIVDFIPHASMNTVHHMILFGCQSPSSASSSWDCGGALGTCKDD-PSIMYAWARNAPPTKLPKDVGFRVGKGSGMSYFVLQVHYGDVSAFRDHHRDCSGLTLRMTSKPQPFVAGIYLLMSVDTVIPPGKTVTNADVACDY-ASYPIYPFAFRTHTHRLGKVVSGYRI--RNGKWTLIGRQSPQLPQAFYPVNTELSVQYGDTVAARCVFTGEGRTSETVIGGTSDDEMCNFY-MMYYMDRRHAVPFMSCMESGSREQFRHIPA---EANVPIAVSPDQMSSMMHMGHAADDSVLLDKRRGGQGADQDYHLEQVTDWPEGNLQLGQVSGLAL------DSDSNLVIFHRGDHHWDLDSFDGRARYQHRSLGPIQQSAILVVDPAKGRILKASGRNMFYLPHGITADRDNNY-WVTDVALHQVLK--VSSDGR--DRT-LLALGEAFTPGSDSSHFCQPTDVAIDPHTGNVFVSDGYCNARILKFSADGKYLSQWGAGSLDRRQRARFQIPHSLAFLSD------RREVCVADRENGRIQCFIADTGEFVKEIKKEEFGGKVFAISYSPAGDGLIYAVNGDSPYHSAPLRG--FVINYTSREILDTFSP-KRKQDFKMPHDLVGGPDGS-VFVGDAGSEEVFKF-----SAEKSHR 698          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRS---ICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDK-----------------NW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSR-GYVFVADGYCNNRVVCFYPNGTYIEEW------QSQDPMF-IVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLS--IYGIKYNPK-NRLIYGITSD-----GDIRGSSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQ 2053
            + L+MPGV   N+D Y+C +FPVP  N++SYIV + P A+ +  HHM+LFGC SP S   S+ C      C++    I++ WAR+A     P + G  VG  S ++YFVLQVHY   +   D     SGL L ++SKP  +V GI+LL S    I P     N DV+C Y  +   Y  AFRTH H LG+ +SGY++   +G+  LIG+ +PQ PQ FY  + ++ ++ GD + ARC+F   G+ S T IG T  DEMCNFY MM   +      F  C  +  ++ +++IP+   E + P   S    +  +   +   D + +DK                 +W + N +LG+VSG+++          ++++ HRG H W   SF  +  YQ     PI    I+ VDP  G +L+ + R +FY+PHGITA +D  Y W+TDVA HQV++  V  D +  D+T  + LG+ F PG D +HFC+P+ VA+D   G VFV+DGYCN R++ F  +G Y+ +W      + Q   F I HS+    D      +  V VADREN +I  F  D       I ++     ++ I Y+P  + LIY +  D       +RG  F  N TS ++     P      F+ PHDL    +G  +FV +   ++V KF     S+ K H+
Sbjct:   80 MDLRMPGVSPSNSDTYLCMAFPVPT-NQDSYIVDFIPHASMNTVHHMILFGCQSPSSASSSWDCGGALGTCKDD-PSIMYAWARNAPPTKLPKDVGFRVGKGSGMSYFVLQVHYGDVSAFRDHHRDCSGLTLRMTSKPQPFVAGIYLLMSVDTVIPPGKTVTNADVACDY-ASYPIYPFAFRTHTHRLGKVVSGYRI--RNGKWTLIGRQSPQLPQAFYPVNTELSVQYGDTVAARCVFTGEGRTSETVIGGTSDDEMCNFY-MMYYMDRRHAVPFMSCMESGSREQFRHIPA---EANVPIAVSPDQMSSMMHMGHAADDSVLLDKRRGGQGADQDYHLEQVTDWPEGNLQLGQVSGLAL------DSDSNLVIFHRGDHHWDLDSFDGRARYQHRSLGPIQQSAILVVDPAKGRILKASGRNMFYLPHGITADRDNNY-WVTDVALHQVLK--VSSDGR--DRT-LLALGEAFTPGSDSSHFCQPTDVAIDPHTGNVFVSDGYCNARILKFSADGKYLSQWGAGSLDRRQRARFQIPHSLAFLSD------RREVCVADRENGRIQCFIADTGEFVKEIKKEEFGGKVFAISYSPAGDGLIYAVNGDSPYHSAPLRG--FVINYTSREILDTFSP-KRKQDFKMPHDLVGGPDGS-VFVGDAGSEEVFKF-----SAEKSHR 727          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC---RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPS-KTISAKTLQNYNFDIDVLKMDKNWKVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSR-GYVFVADGYCNNRVVCFYPNGTYIEEW------QSQDPMF-IVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLS--IYGIKYNPK-NRLIYGITSD-----GDIRGSSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQHSVGNNFNQIHDM 2092
            + L+MPGV   N+D Y+C +FPVP  N++SYIV + P A+ +  HHM+LFGC SP S   S+ C      C++    I++ WAR+A     P + G  VG  S ++YFVLQVHY   +   D     SGL L ++SKP  +V GI+LL S    I P     N DV+C Y  +   Y  AFRTH H LG+ +SGY++   +G+  LIG+ +PQ PQ FY  + ++ ++ GD + ARC+F   G+ S T IG T  DEMCNFY MM   +      F  C  +  ++ +++IP+   E + P   S   +S+     +  D  + ++    + N +LG+VSG+++          ++++ HRG H W   SF  +  YQ     PI    I+ VDP  G +L+ + R +FY+PHGITA +D  Y W+TDVA HQV++  V  D +  D+T  + LG+ F PG D +HFC+P+ VA+D   G VFV+DGYCN R++ F  +G Y+ +W      + Q   F I HS+    D      +  V VADREN +I  F  D       I ++     ++ I Y+P  + LIY +  D       +RG  F  N TS ++     P      F+ PHDL    +G  +FV +   ++V KF     S+ K H+ SV     Q+ ++
Sbjct:   51 MDLRMPGVSPSNSDTYLCMAFPVPT-NQDSYIVDFIPHASMNTVHHMILFGCQSPSSASSSWDCGGALGTCKDD-PSIMYAWARNAPPTKLPKDVGFRVGKGSGMSYFVLQVHYGDVSAFRDHHRDCSGLTLRMTSKPQPFVAGIYLLMSVDTVIPPGKTVTNADVACDY-ASYPIYPFAFRTHTHRLGKVVSGYRI--RNGKWTLIGRQSPQLPQAFYPVNTELSVQYGDTVAARCVFTGEGRTSETVIGGTSDDEMCNFY-MMYYMDRRHAVPFMSCMESGSREQFRHIPA---EANVPIAVSPDQMSSMMHMGHAADYHLEQVTDWPEGNLQLGQVSGLAL------DSDSNLVIFHRGDHHWDLDSFDGRARYQHRSLGPIQQSAILVVDPAKGRILKASGRNMFYLPHGITADRDNNY-WVTDVALHQVLK--VSSDGR--DRT-LLALGEAFTPGSDSSHFCQPTDVAIDPHTGNVFVSDGYCNARILKFSADGKYLSQWGAGSLDRRQRARFQIPHSLAFLSD------RREVCVADRENGRIQCFIADTGEFVKEIKKEEFGGKVFAISYSPAGDGLIYAVNGDSPYHSAPLRG--FVINYTSREILDTFSP-KRKQDFKMPHDLVGGPDGS-VFVGDAGSEEVFKF-----SAEKSHR-SVKKAGIQVQEL 693          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC---RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDK-----------------NW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSR-GYVFVADGYCNNRVVCFYPNGTYIEEW------QSQDPMF-IVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLS--IYGIKYNPK-NRLIYGITSD-----GDIRGSSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQHSVGNNFNQIHDM 2092
            + L+MPGV   N+D Y+C +FPVP  N++SYIV + P A+ +  HHM+LFGC SP S   S+ C      C++    I++ WAR+A     P + G  VG  S ++YFVLQVHY   +   D     SGL L ++SKP  +V GI+LL S    I P     N DV+C Y  +   Y  AFRTH H LG+ +SGY++   +G+  LIG+ +PQ PQ FY  + ++ ++ GD + ARC+F   G+ S T IG T  DEMCNFY MM   +      F  C  +  ++ +++IP+   E + P   S    +  +   +   D + +DK                 +W + N +LG+VSG+++          ++++ HRG H W   SF  +  YQ     PI    I+ VDP  G +L+ + R +FY+PHGITA +D  Y W+TDVA HQV++  V  D +  D+T  + LG+ F PG D +HFC+P+ VA+D   G VFV+DGYCN R++ F  +G Y+ +W      + Q   F I HS+    D      +  V VADREN +I  F  D       I ++     ++ I Y+P  + LIY +  D       +RG  F  N TS ++     P      F+ PHDL    +G  +FV +   ++V KF     S+ K H+ SV     Q+ ++
Sbjct:   51 MDLRMPGVSPSNSDTYLCMAFPVPT-NQDSYIVDFIPHASMNTVHHMILFGCQSPSSASSSWDCGGALGTCKDD-PSIMYAWARNAPPTKLPKDVGFRVGKGSGMSYFVLQVHYGDVSAFRDHHRDCSGLTLRMTSKPQPFVAGIYLLMSVDTVIPPGKTVTNADVACDY-ASYPIYPFAFRTHTHRLGKVVSGYRI--RNGKWTLIGRQSPQLPQAFYPVNTELSVQYGDTVAARCVFTGEGRTSETVIGGTSDDEMCNFY-MMYYMDRRHAVPFMSCMESGSREQFRHIPA---EANVPIAVSPDQMSSMMHMGHAADDSVLLDKRRGGQGADQDYHLEQVTDWPEGNLQLGQVSGLAL------DSDSNLVIFHRGDHHWDLDSFDGRARYQHRSLGPIQQSAILVVDPAKGRILKASGRNMFYLPHGITADRDNNY-WVTDVALHQVLK--VSSDGR--DRT-LLALGEAFTPGSDSSHFCQPTDVAIDPHTGNVFVSDGYCNARILKFSADGKYLSQWGAGSLDRRQRARFQIPHSLAFLSD------RREVCVADRENGRIQCFIADTGEFVKEIKKEEFGGKVFAISYSPAGDGLIYAVNGDSPYHSAPLRG--FVINYTSREILDTFSP-KRKQDFKMPHDLVGGPDGS-VFVGDAGSEEVFKF-----SAEKSHR-SVKKAGIQVQEL 710          

Query:  143 LKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC---RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDK----SGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDK-----------------NW-KVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSR-GYVFVADGYCNNRVVCFYPNGTYIEEW------QSQDPMF-IVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLS--IYGIKYNPK-NRLIYGITSD-----GDIRGSSFTFNTTSSQM----KPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQHSVGNNFNQIHDM 2092
            + L+MPGV   N+D Y+C +FPVP  N++SYIV + P A+ +  HHM+LFGC SP S   S+ C      C++    I++ WAR+A     P + G  VG  S ++YFVLQVHY   +   D     SGL L ++SKP  +V GI+LL S    I P     N DV+C Y  +   Y  AFRTH H LG+ +SGY++   +G+  LIG+ +PQ PQ FY  + ++ ++ GD + ARC+F   G+ S T IG T  DEMCNFY MM   +      F  C  +  ++ +++IP+   E + P   S    +  +   +   D + +DK                 +W + N +LG+VSG+++          ++++ HRG H W   SF  +  YQ     PI    I+ VDP  G +L+ + R +FY+PHGITA +D  Y W+TDVA HQV++  V  D +  D+T  + LG+ F PG D +HFC+P+ VA+D   G VFV+DGYCN R++ F  +G Y+ +W      + Q   F I HS+    D      +  V VADREN +I  F  D       I ++     ++ I Y+P  + LIY +  D       +RG  F  N TS ++     P      F+ PHDL    +G  +FV +   ++V KF     S+ K H+ SV     Q+ ++
Sbjct:   80 MDLRMPGVSPSNSDTYLCMAFPVPT-NQDSYIVDFIPHASMNTVHHMILFGCQSPSSASSSWDCGGALGTCKDD-PSIMYAWARNAPPTKLPKDVGFRVGKGSGMSYFVLQVHYGDVSAFRDHHRDCSGLTLRMTSKPQPFVAGIYLLMSVDTVIPPGKTVTNADVACDY-ASYPIYPFAFRTHTHRLGKVVSGYRI--RNGKWTLIGRQSPQLPQAFYPVNTELSVQYGDTVAARCVFTGEGRTSETVIGGTSDDEMCNFY-MMYYMDRRHAVPFMSCMESGSREQFRHIPA---EANVPIAVSPDQMSSMMHMGHAADDSVLLDKRRGGQGADQDYHLEQVTDWPEGNLQLGQVSGLAL------DSDSNLVIFHRGDHHWDLDSFDGRARYQHRSLGPIQQSAILVVDPAKGRILKASGRNMFYLPHGITADRDNNY-WVTDVALHQVLK--VSSDGR--DRT-LLALGEAFTPGSDSSHFCQPTDVAIDPHTGNVFVSDGYCNARILKFSADGKYLSQWGAGSLDRRQRARFQIPHSLAFLSD------RREVCVADRENGRIQCFIADTGEFVKEIKKEEFGGKVFAISYSPAGDGLIYAVNGDSPYHSAPLRG--FVINYTSREILDTFSP-KRKQDFKMPHDLVGGPDGS-VFVGDAGSEEVFKF-----SAEKSHR-SVKKAGIQVQEL 739          

Query:   80 MLNLRDLFMFLVVIYLANGEKLKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDKNWKVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEWQSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLSIYGIKYNPKNRLIYGITSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQHSVGNNFNQIHDMVKQINPVYIGVLMVAVTVFILICIVTMKYYRRCQXXXXXXXXXXXXXXDKEGFKPLTQEDDGNDDGNSDPETEEYPALRGHLSKKPKV 2356
            M+NLRDLFMFLVVIYLANGEKLKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENS EKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIG THMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDKNWKVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGY+FVADGYCNNRVVCFYPNGTYIEEWQSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLSIYGIKYNPKN+LIYGITSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQHSVGNNFNQIHDMVKQINPVYIGVLMVAVTVFILICIVTMKYYRRCQSGYSKKRRYGKSYKDKEGFKPLTQEDDGNDDGNSDPETEEYPALRGHLSKKPKV
Sbjct:    1 MVNLRDLFMFLVVIYLANGEKLKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPCRSICENSREKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHYLKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYKSAQVQIKPGDILMARCLFDSTGKDSVTEIGYTHMDEMCNFYIMMVTKNTGEENSFSECGGNEFKDLWKNIPSYSMEFDPPNPPSKTISAKTLQNYNFDIDVLKMDKNWKVNKKLGEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFIKDVYQEDLDSPISDYTIVEVDPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYIFVADGYCNNRVVCFYPNGTYIEEWQSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLSIYGIKYNPKNQLIYGITSDGDIRGSSFTFNTTSSQMKPWNTDYSFRAPHDLCLADNGKFIFVAELHLKKVIKFEIAAKSSTKHHQHSVGNNFNQIHDMVKQINPVYIGVLMVAVTVFILICIVTMKYYRRCQSGYSKKRRYGKSYKDKEGFKPLTQEDDGNDDGNSDPETEEYPALRGHLSKKPKV 759          

Query:   98 LFMFLVVIYLA-NGEKLKLQMPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC--------RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHY------LKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYI 907
            +F+ L +++L+    ++ L+MP V     D+YIC +  +   N+  +I  + P A++S AHH+L+  C+ P S +P + C        + IC+ S  KILF WA  A  F  P +  + +G      Y V+Q HY       KP +  D+SG+ + +  KP   + GI+LL +  G I P    V ++ +C Y G +  +  A+R H H+LG+ +SGY +   +     IGK +PQ  Q FY     V+I PGD L ARC+ ++ G D + +IG+T  DEMCNFYI
Sbjct:    2 IFLCLYLLFLSIESHEILLKMPKVRPTKEDQYICHALDL--KNDTLFITGFNPKASASHAHHILIHSCTEPGSVKPYWNCEEMNAKDSKPICK-SGLKILFSWAMAASGFRLPKDVSVMIGKAVGKQYLVIQSHYKNVDYFRKPNSEPDESGIEITVQRKPTSKLAGIYLL-ATDGSI-PGHSTVFMEAACSYTGKTVLHPFAYRVHTHSLGKLVSGYVIHRKNWT--EIGKKSPQVEQMFYPVKGTVKIYPGDTLAARCIMENKG-DKLVKIGNTRKDEMCNFYI 279          

Query:  155 MPGVLAMNNDEYICSSFPVPNHNENSYIVSYEPLANSSIAHHMLLFGCSSPFSTEPSFPC--------RSICENSHEKILFGWARDAKSFHYPSNTGMAVGGKSNINYFVLQVHY------LKPTTIEDKSGLLLELSSKPPDYVVGIFLLFSYYGKIQPQTRKVNLDVSCRYKGNSEAYTLAFRTHAHALGRSISGYKVSLNDGQIELIGKGNPQWPQTFYK-SAQVQIKPGDILMARCLFDSTGKDSVTEIGSTHMDEMCNFYI 907
            MP V     D+YIC +  +   N+  +I  + P A++S AHH+L+  C+ P S +P + C        + IC+ S  KILF WA  A  F  P +  + +G      Y V+Q HY       KP +  D+SG+ + +  KP   + GI+LL +  G I P    V ++ +C Y G +  +  A+R H H+LG+ +SGY +   +     IGK +PQ  Q FY     V+I PGD L ARC+ ++ G D + +IG+T  DEMCNFYI
Sbjct:    1 MPKVRPTKEDQYICHALDL--KNDTLFITGFNPKASASHAHHILIHSCTEPGSVKPYWNCEEMNAKDSKPICK-SGLKILFSWAMAASGFRLPKDVSVMIGKAVGKQYLVIQSHYKNVDYFRKPNSEPDESGIEITVQRKPTSKLAGIYLL-ATDGSI-PGHSTVFMEAACSYTGKTVLHPFAYRVHTHSLGKLVSGYVIHRKNWT--EIGKKSPQVEQMFYPVKGTVKIYPGDTLAARCIMENKG-DKLVKIGNTRKDEMCNFYI 258          

Query: 1052 TLQNYNFDIDVLKMDKNWKVNKKL---GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEV--DPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEW---QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLS---------IYGIKYNPKNRLIYGITS--DGDIRGSSFTFN 1888
            TL+N N       +  NW  +K L   G+VSG+S    K Y     + + HR      ERSF  K+ YQ+  D PI + TI+++  D  +  V+ E    +FY+PHGI A  D  ++  TD+A HQV+R     +       P ++LG+ F PG D NHFCKP+       G +FVADGYCN+R+V F  +G +I E+   + +  + I H + + E      SK+++  ADREN ++    Y   +K T    K +          +Y + +N  N L+Y ++   D   R   F +N
Sbjct:   48 TLENAN-------LVPNWPSSKLLDYLGQVSGLS-FCPKGY-----LYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTIIKINNDIDNAKVVGEFGSNLFYLPHGIFA--DKHHMIATDLARHQVLRIPHNSNK------PDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIE------SKDLICAADRENMRVQ--CYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYN 317          

Query: 1052 TLQNYNFDIDVLKMDKNWKVNKKL---GEVSGVSILLTKQYKLGYSVLVLHRGSHAWTERSFI-KDVYQEDLDSPISDYTIVEV--DPVSGNVLREAARGIFYMPHGITATKDGKYLWITDVAFHQVMRFNVRDDSKLIDKTPSIVLGKRFIPGRDMNHFCKPSQVAVDSRGYVFVADGYCNNRVVCFYPNGTYIEEW---QSQDPMFIVHSITIKEDESGDISKNIVWVADRENRKIIGFGYDGIIKFTHIFRKSLS---------IYGIKYNPKNRLIYGITS--DGDIRGSSFTFN 1888
            TL+N N       +  NW  +K L   G+VSG+S    K Y     + + HR      ERSF  K+ YQ+  D PI + TI+++  D  +  V+ E    +FY+PHGI A  D  ++  TD+A HQV+R     +       P ++LG+ F PG D NHFCKP+       G +FVADGYCN+R+V F  +G +I E+   + +  + I H + + E      SK+++  ADREN ++    Y   +K T    K +          +Y + +N  N L+Y ++   D   R   F +N
Sbjct:   49 TLENAN-------LVPNWPSSKLLDYLGQVSGLS-FCPKGY-----LYIFHRADVEMDERSFNNKNQYQKLSDGPIKESTIIKINNDIDNAKVVGEFGSNLFYLPHGIFA--DKHHMIATDLARHQVLRIPHNSNK------PDLILGEIFTPGNDANHFCKPTHAVAAEDGTIFVADGYCNSRIVKFDKHGKFIGEFGNAKDKSRLSIPHHLVLIE------SKDLICAADRENMRVQ--CYSAGLKVTSKSGKLIKTIKDEKFGPVYAVGFNKLNNLMYVVSDMVDDTDRSRVFIYN 318