Ras and EF-hand domain-containing protein homolog

Overview
NameRas and EF-hand domain-containing protein homolog
Smed IDSMED30027563
Length (bp)2376
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ras and EF-hand domain-containing protein homolog (SMED30027563) t-SNE clustered cells

Violin plots show distribution of expression levels for Ras and EF-hand domain-containing protein homolog (SMED30027563) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ras and EF-hand domain-containing protein homolog (SMED30027563) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ras and EF-hand domain-containing protein homolog (SMED30027563) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30027563

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 16

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30027563h1SMcG0009164 Contig38571uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027563h1SMcG0009164 Contig38571newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027563h1SMcG0009164 Contig30746uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027563h1SMcG0009164 Contig30746newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
cephalic gangliaSMED30027563h1SMcG0009164 dd_Smed_v4_2966_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30027563h1SMcG0009164 dd_Smed_v4_2966_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30027563h1SMcG0009164 dd_Smed_v4_2966_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30027563h1SMcG0009164 dd_Smed_v4_2966_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
secretory systemSMED30027563h1SMcG0009164 dd_Smed_v6_2966_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
zeta neoblastSMED30027563h1SMcG0009164 dd_Smed_v4_2966_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
neoblastSMED30027563h1SMcG0009164 KC916780smed_ncbi_20240424PMID:24903754
Rouhana et al., 2014		whole organism asexual adult fluorescence in situ hybridization evidence
chromatoid bodySMED30027563h1SMcG0009164 KC916780smed_ncbi_20240424PMID:24903754
Rouhana et al., 2014		whole organism asexual adult fluorescence in situ hybridization evidence
neoblastSMED30027563h1SMcG0009165 KC916780smed_ncbi_20240424PMID:24903754
Rouhana et al., 2014		whole organism asexual adult fluorescence in situ hybridization evidence
chromatoid bodySMED30027563h1SMcG0009165 KC916780smed_ncbi_20240424PMID:24903754
Rouhana et al., 2014		whole organism asexual adult fluorescence in situ hybridization evidence
neoblastSMED30027563h1SMcG0009164 SMED_10962_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30027563h1SMcG0009168 SMED_10962_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Human
Match: CRACR2A (calcium release activated channel regulator 2A [Source:HGNC Symbol;Acc:HGNC:28657])

HSP 1 Score: 228.024 bits (580), Expect = 1.654e-63
Identity = 206/715 (28.81%), Postives = 346/715 (48.39%), Query Frame = 2 
Query:  191 QARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFL-----------GAPVEIPHDDDLEF---DDEGSSLNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEEKARKLDKSNFSSSNGSMDLYKELSMAQEQSQPKVIDVADLKKKRGSILSSYFVPKINVDQVSHERCQSMSYDDEDVL-----TDLGTSYNDFSYDAIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLGERSPPDGAVEEVDI----IKG--PEKPERIFKVVFIGDSSVGKTSIIK-----------------------------RFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLD-TKPKKGCCG 2167
            +A+E +  CD E KGFI ++DM RL   LPL+ E+ E VFD+LD D NG LT +EF  GFS F            G  V   H++ +     D++   + +  +     L++++    + ED  ++K+ W QL+     LLS+FE  +  IIS + +A  E N LE  LK K   YDEE++ LY+EM+ QIK+EKE+ L ++ +R +     LE ++  K++  +++ +   +   +   L     E+  E  +L+    EL  +L  T   ++D Q+ ++ L +++ +  + +      +TE +  E+  L++QLD LRE NK L++E+                D+       +          A  KK+ GS++  Y      VD  S    +S S ++E+V      + LG S    + +             P     +    S +E  +  L+D     G   P     EE ++    ++G  PE P             VGK ++ K                             RFC + F S G+A+T+G+D+++K++ +    VALQ+WDTAGQER+R IT  ++RK+DGV+++YD+  + S +++R+W+ +V+EAV D   +L+L NK D    E+ R     L + L  E N++++ CSA +G N  E+   +A+ L  +E+   +  I++     KK CCG
Sbjct:   54 KAQEFFQTCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQNNPSQEDAGEQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVKQLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHETKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQREKAGLLKQLDFLRERNKHLRDER----------------DIC--FQKNKAAKANTAASRASWKKRSGSVIGKY------VD--SRGILRSQSEEEEEVFGIPRRSSLGLSGYPLTEEEPGTGEPGPGGPYPRPLRRII---SVEEDPLPQLLDG----GFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRF-SPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLD---NEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQVGHPAKKKSCCG 731
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Human
Match: AL358472.6 (novel protein)

HSP 1 Score: 141.354 bits (355), Expect = 9.614e-38
Identity = 72/168 (42.86%), Postives = 109/168 (64.88%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVEN-VLYFHCSAKTGENINEAFQLMAKNL 2095
            + +FK++ IGDS VGKT +I RF  + F +  I STIG+DF+I+++ I    + LQ+WDTAGQERF++IT+ YYR + G+++VYDI  E S  N++ WM+++KE        L+L NKCDM   E  R       D L  E+ + +F  SAK+  N++EAF  +A+++
Sbjct:    6 DHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYI-STIGIDFKIRTVDIEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDM---EAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDI 169
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Human
Match: RAB13 (RAB13, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9762])

HSP 1 Score: 141.354 bits (355), Expect = 9.614e-38
Identity = 72/168 (42.86%), Postives = 109/168 (64.88%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVEN-VLYFHCSAKTGENINEAFQLMAKNL 2095
            + +FK++ IGDS VGKT +I RF  + F +  I STIG+DF+I+++ I    + LQ+WDTAGQERF++IT+ YYR + G+++VYDI  E S  N++ WM+++KE        L+L NKCDM   E  R       D L  E+ + +F  SAK+  N++EAF  +A+++
Sbjct:    6 DHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYI-STIGIDFKIRTVDIEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDM---EAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDI 169
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Human
Match: RAB8B (RAB8B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30273])

HSP 1 Score: 139.813 bits (351), Expect = 4.465e-37
Identity = 71/175 (40.57%), Postives = 111/175 (63.43%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQAS--RLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDL 2119
            +FK++ IGDS VGKT ++ RF  + F +  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI +E S  N++ W+ N++E    +   ++L NKCDM     ++ Q S  R + L     + +   SAK+  N+ EAF  +A+++  K N  +
Sbjct:    8 LFKLLLIGDSGVGKTCLLFRFSEDAFNTTFI-STIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDM----NDKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKM 177
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Human
Match: RAB8B (RAB8B, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:30273])

HSP 1 Score: 137.887 bits (346), Expect = 1.017e-36
Identity = 71/175 (40.57%), Postives = 111/175 (63.43%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQAS--RLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDL 2119
            +FK++ IGDS VGKT ++ RF  + F +  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI +E S  N++ W+ N++E    +   ++L NKCDM     ++ Q S  R + L     + +   SAK+  N+ EAF  +A+++  K N  +
Sbjct:    8 LFKLLLIGDSGVGKTCLLFRFSEDAFNTTFI-STIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDM----NDKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKM 177
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Celegans
Match: 4R79.2 (pep chromosome:WBcel235:IV:17480396:17482329:-1 gene:WBGene00007067.1 transcript:4R79.2b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:4R79.2)

HSP 1 Score: 187.193 bits (474), Expect = 3.600e-53
Identity = 90/198 (45.45%), Postives = 135/198 (68.18%), Query Frame = 2 
Query: 1589 KPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGE-YFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDT----KPKKGCC 2164
            +P+RIFKVVF+GDS+VGKT  + RFC+N F+     +TIGVDF +K+++I     +A+Q+WDTAGQERFRSIT  Y+RK+DGVV+++D+ SE S +N+R W+++V+  V+D TV+ ++ NK D+   +  R+   R  + L VE  + +F  SA TG  I+   + MA+NL  +E+N L+ A+KLD     K +  CC
Sbjct:  114 QPDRIFKVVFVGDSAVGKTCFLHRFCHNRFKP-LFNATIGVDFTVKTMKIPPNRAIAMQLWDTAGQERFRSITKQYFRKADGVVLMFDVTSEQSFLNVRNWIDSVRAGVDDATVMCLVGNKMDLFGSDIARSAVYRAAEKLAVEFKIPFFETSAYTGFGIDTCMRQMAENLQRREDNHLEEALKLDINSNYKKRSWCC 310
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Celegans
Match: 4R79.2 (pep chromosome:WBcel235:IV:17480396:17483332:-1 gene:WBGene00007067.1 transcript:4R79.2a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:4R79.2)

HSP 1 Score: 187.578 bits (475), Expect = 2.886e-52
Identity = 90/198 (45.45%), Postives = 135/198 (68.18%), Query Frame = 2 
Query: 1589 KPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGE-YFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDT----KPKKGCC 2164
            +P+RIFKVVF+GDS+VGKT  + RFC+N F+     +TIGVDF +K+++I     +A+Q+WDTAGQERFRSIT  Y+RK+DGVV+++D+ SE S +N+R W+++V+  V+D TV+ ++ NK D+   +  R+   R  + L VE  + +F  SA TG  I+   + MA+NL  +E+N L+ A+KLD     K +  CC
Sbjct:  198 QPDRIFKVVFVGDSAVGKTCFLHRFCHNRFKP-LFNATIGVDFTVKTMKIPPNRAIAMQLWDTAGQERFRSITKQYFRKADGVVLMFDVTSEQSFLNVRNWIDSVRAGVDDATVMCLVGNKMDLFGSDIARSAVYRAAEKLAVEFKIPFFETSAYTGFGIDTCMRQMAENLQRREDNHLEEALKLDINSNYKKRSWCC 394
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Celegans
Match: rab-8 (RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5EFC1])

HSP 1 Score: 139.813 bits (351), Expect = 2.042e-37
Identity = 72/178 (40.45%), Postives = 116/178 (65.17%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNK-ENNDLKTA 2128
            +FK++ IGDS VGKT ++ RF ++ F +  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI +E S  N++ W+ N++E    +   +++ NKCD+   EE R  +    + L +E    +   SAK   NI+EAF  +A+++ +K E N+++  
Sbjct:    8 LFKLLLIGDSGVGKTCVLFRFSDDSFNNSFI-STIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIILVYDITNERSFENIKNWIRNIEEHAASDVERMIIGNKCDI---EERREVSRDRGEQLAIEYGTKFLETSAKANLNIDEAFFTLARDIKSKMEQNEMRAG 181
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Celegans
Match: rab-8 (RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5EFC1])

HSP 1 Score: 139.813 bits (351), Expect = 2.042e-37
Identity = 72/178 (40.45%), Postives = 116/178 (65.17%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNK-ENNDLKTA 2128
            +FK++ IGDS VGKT ++ RF ++ F +  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI +E S  N++ W+ N++E    +   +++ NKCD+   EE R  +    + L +E    +   SAK   NI+EAF  +A+++ +K E N+++  
Sbjct:    8 LFKLLLIGDSGVGKTCVLFRFSDDSFNNSFI-STIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIILVYDITNERSFENIKNWIRNIEEHAASDVERMIIGNKCDI---EERREVSRDRGEQLAIEYGTKFLETSAKANLNIDEAFFTLARDIKSKMEQNEMRAG 181
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Celegans
Match: rsef-1 (Ras and EF-hand domain-containing protein homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22908])

HSP 1 Score: 146.362 bits (368), Expect = 2.556e-36
Identity = 86/259 (33.20%), Postives = 144/259 (55.60%), Query Frame = 2 
Query: 1415 VENNVTSSHN----PIHSTSVALSPS-YQEMEIQT--LIDNEEKLGERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLK-TAIKLDTK-PKKGCC 2164
            VEN  TS++     P+H+ S     + +  +E +T  ++D+   L     P G +  ++   GP   ER F++V  GD++VGK+S + R    +F ++ + ST+GVDF +K++ +    VALQ+WDTAGQERFRS+   Y+R++DG ++VYD+ +E S + +R W+E +KE+ E    I+++ NK DM          +    +     VL+   SA  G NI+ A   + + L   E+ +++ T + L+    KKG C
Sbjct:  395 VENFQTSTNVFRSVPLHAISTEEQGTIFGTIEEKTSLILDDAHSLQGLDTP-GDLMGLNDANGP--AERTFRIVMCGDAAVGKSSFVMRVIRRQFTNQ-LPSTLGVDFHVKTVNVDGRNVALQLWDTAGQERFRSLCKSYFRRADGAILVYDVCAEQSFLRVRDWIETIKESTERSIPIILVGNKVDMRISTPGSVAKTDGASMAAAMGVLFMETSALDGSNIDNAMLALTRELMAVEDVEIRSTGVVLNPAVAKKGGC 649
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Fly
Match: Rab8 (gene:FBgn0262518 transcript:FBtr0308833)

HSP 1 Score: 134.42 bits (337), Expect = 1.365e-35
Identity = 68/169 (40.24%), Postives = 106/169 (62.72%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNK 2104
            +FK++ IGDS VGKT I+ RF  + F +  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI  E S  N++ W+ N++E    +   ++L NKC++    + R  +    + L +E  + +   SAK   N+ EAF  +A ++  K
Sbjct:    8 LFKLLLIGDSGVGKTCILFRFSEDAFNTTFI-STIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELT---DKRQVSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAK 172
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Fly
Match: Rab8 (gene:FBgn0262518 transcript:FBtr0074921)

HSP 1 Score: 134.42 bits (337), Expect = 1.365e-35
Identity = 68/169 (40.24%), Postives = 106/169 (62.72%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNK 2104
            +FK++ IGDS VGKT I+ RF  + F +  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI  E S  N++ W+ N++E    +   ++L NKC++    + R  +    + L +E  + +   SAK   N+ EAF  +A ++  K
Sbjct:    8 LFKLLLIGDSGVGKTCILFRFSEDAFNTTFI-STIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELT---DKRQVSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAK 172
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Fly
Match: Rab19 (gene:FBgn0015793 transcript:FBtr0331832)

HSP 1 Score: 134.42 bits (337), Expect = 2.502e-35
Identity = 76/198 (38.38%), Postives = 111/198 (56.06%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDM-----VQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDT------KPKKGC 2161
            +FK+V IGD   GKT I+ RF    +  E   +TIGVDF +K+I +    + LQIWDTAGQERFR+IT  YYR ++GV++VYDI   SS  NL++W+E V+       +I+++ NKCD+     V  EE R     + ++L V        SAK   N+ +AF+ +A  L  + + +    +  +T      KP K C
Sbjct:   21 LFKIVLIGDCGTGKTCIVDRFKTGNY-IERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQERFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFEEARQMCQYIPEILFV-----METSAKENMNVEDAFRCLANELKRQHDANNVEEVPENTITLGQGKPLKSC 212
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Fly
Match: Rab19 (gene:FBgn0015793 transcript:FBtr0076705)

HSP 1 Score: 134.42 bits (337), Expect = 2.502e-35
Identity = 76/198 (38.38%), Postives = 111/198 (56.06%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDM-----VQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDT------KPKKGC 2161
            +FK+V IGD   GKT I+ RF    +  E   +TIGVDF +K+I +    + LQIWDTAGQERFR+IT  YYR ++GV++VYDI   SS  NL++W+E V+       +I+++ NKCD+     V  EE R     + ++L V        SAK   N+ +AF+ +A  L  + + +    +  +T      KP K C
Sbjct:   21 LFKIVLIGDCGTGKTCIVDRFKTGNY-IERHGNTIGVDFSMKTIAVEGKQIKLQIWDTAGQERFRTITQSYYRSANGVLIVYDITKRSSFSNLQKWIEEVRRYTASNVLIILVGNKCDLEEQREVDFEEARQMCQYIPEILFV-----METSAKENMNVEDAFRCLANELKRQHDANNVEEVPENTITLGQGKPLKSC 212
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Fly
Match: Rab1 (gene:FBgn0285937 transcript:FBtr0084104)

HSP 1 Score: 133.265 bits (334), Expect = 3.503e-35
Identity = 72/201 (35.82%), Postives = 117/201 (58.21%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGE-ENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNK-----ENNDLKTAIKLD-TKP----KKGCC 2164
            + +FK++ IGDS VGK+ ++ RF ++ + +E   STIGVDF+I++I +    + LQIWDTAGQERFR+ITS YYR + G+++VYD   + S  N++QW+E ++    +    L++ NK D+   +  +   A+     L +    +   SAK+  N+ +AF  MA  + N+        D  + +K+D  +P    K GCC
Sbjct:    9 DYLFKLLLIGDSGVGKSCLLLRFADDTY-TESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDCTDQESFNNVKQWLEEIERYACENVNKLLVGNKSDLTTKKVVDHTTAAEYAAQLGIP---FLETSAKSATNVEQAFMTMAAEIKNRVGPPSSATDNASKVKIDQGRPVENTKSGCC 205
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Zebrafish
Match: cracr2ab (calcium release activated channel regulator 2Ab [Source:ZFIN;Acc:ZDB-GENE-041210-94])

HSP 1 Score: 182.956 bits (463), Expect = 1.095e-49
Identity = 82/194 (42.27%), Postives = 134/194 (69.07%), Query Frame = 2 
Query: 1592 PERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP--KKGCC 2164
            P+R+FKV+ +G+SSVGKT++++RFC+ +F S   ++T+G+D+ ++++ +G+  VALQ+WDTAGQER+RSIT  ++RK+DGVV++YDI  E S  ++R W+ +++EAV D   +++L NK D    E  R   ++  DLL  E N++++ CSA TG N+ EA   +A+ L  +E+      ++L  +P  KK CC
Sbjct:  281 PQRLFKVILVGNSSVGKTALLRRFCDGQFHS-ATSATVGIDYSVRTLNLGDSHVALQLWDTAGQERYRSITKQFFRKADGVVVIYDITMEDSFSSVRPWLSSIQEAVGDPIPVMLLGNKSDK---ENEREVQTKEADLLAEEANLMFYECSAYTGANVLEAMIHLARVLREQEDRVWVNTVRLGDQPLKKKTCC 470
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Zebrafish
Match: cracr2ab (calcium release activated channel regulator 2Ab [Source:ZFIN;Acc:ZDB-GENE-041210-94])

HSP 1 Score: 184.111 bits (466), Expect = 3.489e-48
Identity = 82/194 (42.27%), Postives = 134/194 (69.07%), Query Frame = 2 
Query: 1592 PERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP--KKGCC 2164
            P+R+FKV+ +G+SSVGKT++++RFC+ +F S   ++T+G+D+ ++++ +G+  VALQ+WDTAGQER+RSIT  ++RK+DGVV++YDI  E S  ++R W+ +++EAV D   +++L NK D    E  R   ++  DLL  E N++++ CSA TG N+ EA   +A+ L  +E+      ++L  +P  KK CC
Sbjct:  583 PQRLFKVILVGNSSVGKTALLRRFCDGQFHS-ATSATVGIDYSVRTLNLGDSHVALQLWDTAGQERYRSITKQFFRKADGVVVIYDITMEDSFSSVRPWLSSIQEAVGDPIPVMLLGNKSDK---ENEREVQTKEADLLAEEANLMFYECSAYTGANVLEAMIHLARVLREQEDRVWVNTVRLGDQPLKKKTCC 772

HSP 2 Score: 139.813 bits (351), Expect = 9.149e-34
Identity = 105/332 (31.63%), Postives = 178/332 (53.61%), Query Frame = 2 
Query:  188 DQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFL-GAPVEI-------PHDDDLEFDDEGSSLNQVA-------QEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEEK 1138
            D+ ++ + +CD E KGFIT+ DM RL   LPL  E+ E+VFDSLD D NG LTL +F  GFS FL G  V +       P     E   + S   QV        ++H   L+E +    + ED   ++  W QL+     LLS+FE  +  +   + +A++E   +E  L+ K+  +D E++RLY+EM+ QI  EK+R   ++ +  +    +L+  +R K++  +++ +   +  ++ ++L     ES  E  +L+    EL   L  T + +   QE +  L +++ + +  R      +TEG+  E++SL++QLD LRE+NK L++E+
Sbjct:   45 DKLKDFFHICDSEGKGFITRTDMRRLHKELPLTAEELENVFDSLDVDKNGFLTLGKFSSGFSSFLHGRRVSMTEELTTTPSQKAPEAAGQSSEDEQVMKTIEDDEEKHFSMLMESLGASNVFEDPSEVRSLWAQLRKDEPHLLSNFEEFLSRVTFQIKEAQHERKEMESALRRKAVTHDTEIQRLYEEMEQQIINEKDRANLKDSESLQIRSQDLQQLLRGKEQELEQLFQKQRRLERQCRDLHSEQQESRLENVKLKMNNEELSRDLEHTCEELVLAQEQLAILQEQASRLQEEREMEMYRVTEGLQREKQSLMKQLDLLREMNKHLRDER 376
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Zebrafish
Match: CABZ01062083.1 (calcium release activated channel regulator 2Aa [Source:NCBI gene;Acc:100330395])

HSP 1 Score: 167.162 bits (422), Expect = 1.123e-42
Identity = 77/194 (39.69%), Postives = 129/194 (66.49%), Query Frame = 2 
Query: 1592 PERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP--KKGCC 2164
            P+R+FKVV +G+SSVGKTS+++RFC++ F S G  +T+G+D+ +K++ +    +ALQ+WDTAGQER+RSIT  ++RK+DGVV+VYDI +E +   +RQW+ +V+E   ++  I++L NK D+   +  R     L + L  +  ++++ CSA +  N+ ++   MA+ L  +E+ + +  + L   P  KK CC
Sbjct:  529 PDRLFKVVLVGNSSVGKTSLLRRFCDDCFHS-GTCATVGIDYSVKTLSVDNSQIALQMWDTAGQERYRSITKQFFRKADGVVVVYDITNEQTFTAVRQWLASVQEGAGEDIPIMLLGNKTDL---DSQRVIPLGLGEKLAKDFQLMFYECSAFSNHNVTDSMIHMARILKEQEDREKEKTVSLVDSPSKKKSCC 718

HSP 2 Score: 144.05 bits (362), Expect = 3.377e-35
Identity = 116/350 (33.14%), Postives = 191/350 (54.57%), Query Frame = 2 
Query:  140 GLNQKIMSQAHHSIFEDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDD----------------DLEFDDEGSSLNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTV-KELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEEK 1138
            G ++   S++  S   ++ RE + +CD E KGFIT+ DM RL   LPL+ +  E+VFDSLD D NG LT EEF  GFS+F+  P  +P D                 + ++++  S      ++H   L+E +    + ED + ++  W QL+     LLS+FE  +  +   + +A  E   +E  LK KS  +D+E++RLY+EM+ QIK EK+R+L E+ +R      ++E ++  K+K   EIL +  K + ++ ++L     E+S E  +L++   +L  +L  T + +   QE +  L ++S +    R      +TE +  ER SL++QLD LRE+NK L++EK
Sbjct:   20 GDSKGTPSESDCSAVIEKTREFFQICDVEGKGFITRRDMQRLNGELPLSADDLENVFDSLDADANGYLTFEEFSSGFSEFMFGPSVVPADPHGGEELVSRKSPEMLYESQWEERLSRGEDDEEKHFCMLMENLGASNIFEDPEEVRSLWVQLRRDEPHLLSNFEEFLARVTYQIKEANQEKKEMETALKRKSATHDDEIQRLYEEMEQQIKNEKDRILLEDSERFLTRSQDMEHQLLSKEKEL-EILSNKQKRLERQCRDLLSEQRETSVENVKLKRYNEDLSRELDHTSQELSLAQEQLMLLQEQSSRLHEEREMEIYRVTESLQRERTSLLKQLDLLREMNKHLRDEK 368
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Zebrafish
Match: rab13 (RAB13, member RAS oncogene family [Source:NCBI gene;Acc:373105])

HSP 1 Score: 140.969 bits (354), Expect = 9.582e-38
Identity = 73/177 (41.24%), Postives = 113/177 (63.84%), Query Frame = 2 
Query: 1583 PEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVEN-VLYFHCSAKTGENINEAFQLMAKNLTNKEN 2110
             +K + +FK++ IGDS VGKT +I RF  + F S  I STIG+DF++K+I +    V LQ+WDTAGQERF++IT+ YYR + G+++VYDI  E S  N++ WM+++KE        ++L NKCD+   E  R  +    + L  E+ + +F  SAK+  N+ E+F  +A+++  K N
Sbjct:    2 AKKYDFLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYI-STIGIDFKVKTIEVEGKKVKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSYENIQNWMKSIKENASAGVSRMLLGNKCDI---EAKRKVSKETGEKLAKEHGIRFFETSAKSSINVEESFTSLARDILLKSN 174
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Zebrafish
Match: megf8 (multiple EGF-like-domains 8 [Source:ZFIN;Acc:ZDB-GENE-090730-1])

HSP 1 Score: 139.813 bits (351), Expect = 9.924e-38
Identity = 70/166 (42.17%), Postives = 108/166 (65.06%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNL 2095
            +FK++ IGDS VGKT ++ RF  + F +  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI SE S  N++ W+ N++E    +   ++L NKCDM    E R  +    + L ++  + +   SAKT  N+ EAF  +A+++
Sbjct:    8 LFKLLLIGDSGVGKTCLLFRFSEDAFNTTFI-STIGIDFKIRTIELNGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITSEKSFENIKNWIRNIEEHASSDVEKMILGNKCDM---NERRQVSKERGEKLAIDYGIKFLETSAKTSINVEEAFFTLARDI 169
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Xenopus
Match: pknox2 (PBX/knotted 1 homeobox 2 [Source:Xenbase;Acc:XB-GENE-853128])

HSP 1 Score: 141.354 bits (355), Expect = 9.776e-38
Identity = 73/179 (40.78%), Postives = 116/179 (64.80%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLK-DLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAI 2131
            +FK++ IGDS VGKT ++ RF  + F +  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI +E S  N++ W+ N++E    +   ++L NKCDM     ++ Q SR K + L ++  + +   SAK+  N+ EAF  +A+++  K N  +  +I
Sbjct:    8 LFKLLLIGDSGVGKTCLLFRFSEDAFNTTFI-STIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDM----NDKRQVSREKGEKLAIDYGIKFLETSAKSSINVEEAFFTLARDIMTKLNRKMNESI 181
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Xenopus
Match: irf6 (interferon regulatory factor 6 [Source:Xenbase;Acc:XB-GENE-876410])

HSP 1 Score: 146.362 bits (368), Expect = 1.111e-36
Identity = 75/216 (34.72%), Postives = 122/216 (56.48%), Query Frame = 2 
Query: 1553 AVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQ----ASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENND--------LKTAIKLDTKPKKGCC 2164
            + E VD +      E+ +K+V  GD++VGK+S + R C NEFR    ++T+GVDFQ+K++ +      LQ+WDTAGQERFRSI   Y+R++DGV+++YD+  E S +N+R+W++ +++A  +   I+++ NK D+ Q    +       +  + L      L+   SAK G NI EA   +A+ +  + +N+        L  AI       K CC
Sbjct:  291 SAETVDKVHKYTHAEKAYKIVLAGDAAVGKSSFLMRLCKNEFRG-NTSATLGVDFQMKTLVVDGEPTILQLWDTAGQERFRSIAKSYFRRADGVLLLYDVTCEKSFLNVREWIDMIEDATSEAIPIMMVGNKADLRQLMAEQGHICVSTNYGEKLSRTYGALFCETSAKEGSNIVEAVLHLAREVRKRCDNEDDRGSVTNLSAAISKKPAQMKNCC 505
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Xenopus
Match: erich3 (glutamate rich 3 [Source:Xenbase;Acc:XB-GENE-5880720])

HSP 1 Score: 147.902 bits (372), Expect = 2.018e-36
Identity = 120/386 (31.09%), Postives = 186/386 (48.19%), Query Frame = 2 
Query: 1070 ERESLVRQLDELREINKQLQE------------EKARKLDKSNFSSSNGSMDLYKELSMAQEQSQPKVIDVADLKKKRGSILSSYFVPKINVDQVSHERCQSMSYDDEDVLTDLGTSYNDFSYDAIRVENNVTSSHNPIHS---TSVALSPSYQEMEIQTLIDNEEKLGERSPPDGAV--EEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMA---KNLTNKENNDLKTAIKLDTKPKKG-CC 2164
            ER +   Q+  L E NK L +            E  RK   S    S  S+  Y   + A E    K  DVA    +   I S   +P+            S+ Y D D  ++ G+ +++ S +  R   ++   ++ I S     +  SPS      ++   ++ KL   +P    V  EEV     P     I+++V  GD+  GK+S + R C NEFR + I +T+GVDFQIK + +      LQIWDTAGQERFRSI   Y+RK+ GV+++YD+ SE S +N+RQW++ +K + +    ++++ NK D ++ E +  Q S  + L    + L+   SAK G N+ EA   +A   K  T+ E  + +    L  + KK  CC
Sbjct:  292 ERRTFANQIQILNEANKSLYDNNDSMRSTLTNMENERKRHSSPSRLSEPSVITYSSFT-ADEDPYRKFSDVATWADR--CIDSGVSLPR------------SVGYSDVD--SEFGSEHSNSSEE--RWNGSIHYGNSEIESEVDGKLKWSPSRPLSRAESSASSKRKLPAFTPRKQGVPSEEVSQASSP-----IYRLVLAGDAGSGKSSFLLRLCLNEFRGD-IPTTLGVDFQIKKLLVDGDHTTLQIWDTAGQERFRSIAKSYFRKAHGVLLMYDVTSERSFLNVRQWIDEIKNSSDKPIPMMLIGNKTD-IRTELDGIQTSMGEKLAMAYSSLFCETSAKDGTNVVEAVLHLAREVKKCTDLEGENKEPVTLLSIQDKKANCC 651
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Xenopus
Match: erich3 (glutamate rich 3 [Source:Xenbase;Acc:XB-GENE-5880720])

HSP 1 Score: 147.132 bits (370), Expect = 2.704e-36
Identity = 96/286 (33.57%), Postives = 155/286 (54.20%), Query Frame = 2 
Query: 1334 QSMSYDDEDVLTDLGTSYNDFSYDAIRVENNVTSSHNPIHS---TSVALSPSYQEMEIQTLIDNEEKLGERSPPDGAV--EEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMA---KNLTNKENNDLKTAIKLDTKPKKG-CC 2164
            +S+ Y D D  ++ G+ +++ S +  R   ++   ++ I S     +  SPS      ++   ++ KL   +P    V  EEV     P     I+++V  GD+  GK+S + R C NEFR + I +T+GVDFQIK + +      LQIWDTAGQERFRSI   Y+RK+ GV+++YD+ SE S +N+RQW++ +K + +    ++++ NK D ++ E +  Q S  + L    + L+   SAK G N+ EA   +A   K  T+ E  + +    L  + KK  CC
Sbjct:  354 RSVGYSDVD--SEFGSEHSNSSEE--RWNGSIHYGNSEIESEVDGKLKWSPSRPLSRAESSASSKRKLPAFTPRKQGVPSEEVSQASSP-----IYRLVLAGDAGSGKSSFLLRLCLNEFRGD-IPTTLGVDFQIKKLLVDGDHTTLQIWDTAGQERFRSIAKSYFRKAHGVLLMYDVTSERSFLNVRQWIDEIKNSSDKPIPMMLIGNKTD-IRTELDGIQTSMGEKLAMAYSSLFCETSAKDGTNVVEAVLHLAREVKKCTDLEGENKEPVTLLSIQDKKANCC 628
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Xenopus
Match: irf6 (interferon regulatory factor 6 [Source:Xenbase;Acc:XB-GENE-876410])

HSP 1 Score: 147.902 bits (372), Expect = 2.950e-36
Identity = 77/216 (35.65%), Postives = 123/216 (56.94%), Query Frame = 2 
Query: 1553 AVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQ--GEENRNQASR--LKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENND--------LKTAIKLDTKPKKGCC 2164
            + E VD +      E+ +K+V  GD++VGK+S + R C NEFR    ++T+GVDFQ+K++ +      LQ+WDTAGQERFRSI   Y+R++DGV+++YD+  E S +N+R+W++ +++A  +   I+++ NK D+ Q   E+     S    + L      L+   SAK G NI EA   +A+ +  + +N+        L  AI       K CC
Sbjct:  482 SAETVDKVHKYTHAEKAYKIVLAGDAAVGKSSFLMRLCKNEFRG-NTSATLGVDFQMKTLVVDGEPTILQLWDTAGQERFRSIAKSYFRRADGVLLLYDVTCEKSFLNVREWIDMIEDATSEAIPIMMVGNKADLRQLMAEQGHICVSTNYGEKLSRTYGALFCETSAKEGSNIVEAVLHLAREVRKRCDNEDDRGSVTNLSAAISKKPAQMKNCC 696
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Mouse
Match: Cracr2a (calcium release activated channel regulator 2A [Source:MGI Symbol;Acc:MGI:2685919])

HSP 1 Score: 261.151 bits (666), Expect = 9.981e-76
Identity = 215/724 (29.70%), Postives = 360/724 (49.72%), Query Frame = 2 
Query:  173 HSIFEDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDDLEFDDEGSSLNQVAQ-----------------------EHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEEKARKLDKSNFSSSNGSMDLYKELSMAQEQSQPKVIDVADLKKKRGSILSSYFVPKINVDQVSHERCQSMSYDDEDVLT------------------DLGTSYNDFSYDAIRVENNVTS-SHNPIHS-------TSVALSPSYQEM-----EIQTLIDNEEKLGERSPPDGAVEEVDIIKG---PEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP-KKGCCG 2167
             S    +A+E +  CD E KGFI + DM RL   LPL+ E+ E VFD+LD D NG LT EEF  GFS F           +++ ++E     QVAQ                          + L++++    + ED  ++++ W QL+     LLS+FE L+ TI + + +A  + N LE  L+ K   YDEE++ LY+EM+ QIK+E+E+ L ++ +R +     LE ++  K++  + + +   K   +   L +   E+  E  +L     EL  +L  T   +++ Q+ ++ L +++ + ++ +      +TE +  E+  L++QLD LRE NK L++E+     K   + +N                       A  K++ GS++  Y      VD     R QS   ++EDV +                  DLGT          +    + S   +P+           ++  P  +E+     E Q++      L   SP    V +  + K    P  P+R+FK+VF+GDS+VGKTS ++R C   F S G+A+T+G+D+++K++ +    VALQ+WDTAGQER+R I+  ++RK+DGV ++YD+ ++ S +++RQW+ +V+EAV D   +L+L NK D    E+ R     L + L  E N++++ CSA +G N  E+   +A+ L  +E+      I++     KK CCG
Sbjct:   42 QSAMWKKAQEFFQTCDSEGKGFIARTDMQRLHQELPLSLEELEDVFDALDADGNGFLTPEEFTTGFSHFF-------FSQNIQGEEEAD--QQVAQLQEEKVYQSRGEEDVGDMDHDEEAQFQMLMDRLGAQKVLEDESDVRQLWLQLRKDEPHLLSNFEDLLTTIFAQLQEAHEQKNELECALRKKIAAYDEEIQHLYEEMEQQIKSEREQFLLKDTERFQARSRELEKKLSAKEQELERLNQKQRKLEGQCAALHNDKHETKAENSKLRLTNQELARELERTSHQLQEAQQQLESLQREACELQQEKEMEVYRVTESLQREKSGLLKQLDFLRERNKHLRDERDITFQKDKAAKAN------------------TAASKASRKQRSGSVIGKY------VDGRGILRSQS--EEEEDVFSAPRRRSSVGLSAYLQAEEDLGTGEPGSGVPRRQALRRIISIEEDPLPQLLEGGFEKPLSRCPEEEEVSDQGTERQSVAAPVLDLIPTSPRGQPVGKETLYKEERVPSTPDRLFKIVFVGDSAVGKTSFLRRLCEARF-SPGMAATVGIDYRVKTVTVDNAQVALQLWDTAGQERYRCISQQFFRKADGVAVMYDLTAKQSFLSIRQWLSSVEEAVGDRIPVLLLGNKLD---NEKEREVPRGLGEQLAKENNLIFYECSACSGHNAQESLLHLARLLKEQEDTVRNDTIQVGPPAKKKSCCG 726
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Mouse
Match: Rab13 (RAB13, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1927232])

HSP 1 Score: 144.436 bits (363), Expect = 5.940e-39
Identity = 72/168 (42.86%), Postives = 110/168 (65.48%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDM-VQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNL 2095
            + +FK++ IGDS VGKT +I RF  + F S  I STIG+DF+I+++ I    + LQ+WDTAGQERF++IT+ YYR + G+++VYDI  E S  N++ WM+++KE        L+L NKCDM  + +  R QA +L        + +F  SAK+  N++EAF  +A+++
Sbjct:    6 DHLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYI-STIGIDFKIRTVDIEGKRIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRQVQREQAEKLA---REHRIRFFETSAKSSVNVDEAFSSLARDI 169
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Mouse
Match: Rab8b (RAB8B, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:2442982])

HSP 1 Score: 139.813 bits (351), Expect = 2.948e-37
Identity = 71/175 (40.57%), Postives = 111/175 (63.43%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQAS--RLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDL 2119
            +FK++ IGDS VGKT ++ RF  + F +  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI +E S  N++ W+ N++E    +   ++L NKCDM     ++ Q S  R + L     + +   SAK+  N+ EAF  +A+++  K N  +
Sbjct:    8 LFKLLLIGDSGVGKTCLLFRFSEDAFNTTFI-STIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDM----NDKRQVSKERGEKLAIDYGIKFLETSAKSSTNVEEAFFTLARDIMTKLNRKM 177
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Mouse
Match: Rab1b (RAB1B, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1923558])

HSP 1 Score: 138.272 bits (347), Expect = 8.055e-37
Identity = 70/199 (35.18%), Postives = 115/199 (57.79%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTA-----IKLDTKPKK----GCC 2164
            + +FK++ IGDS VGK+ ++ RF ++ + +E   STIGVDF+I++I +    + LQIWDTAGQERFR+ITS YYR + G+++VYD+  + S  N++QW++ +     +    L++ NK D+   +   N  +  K+  +   V +   SAK   N+ +AF  MA  +  +      +      +K+D+ P K    GCC
Sbjct:    6 DYLFKLLLIGDSGVGKSCLLLRFADDTY-TESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNTTA--KEFADSLGVPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASGGERPNLKIDSTPVKPASGGCC 201
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Mouse
Match: Rab1a (RAB1A, member RAS oncogene family [Source:MGI Symbol;Acc:MGI:97842])

HSP 1 Score: 136.346 bits (342), Expect = 5.039e-36
Identity = 72/205 (35.12%), Postives = 117/205 (57.07%), Query Frame = 2 
Query: 1583 PEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGE-ENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDL------KTAIKLDTKPKK----GCC 2164
            PE  + +FK++ IGDS VGK+ ++ RF ++ + +E   STIGVDF+I++I +    + LQIWDTAGQERFR+ITS YYR + G+++VYD+  + S  N++QW++ +     +    L++ NKCD+   +  +   A    D L +    +   SAK   N+ ++F  MA  +  +           K+ +K+ + P K    GCC
Sbjct:    6 PEY-DYLFKLLLIGDSGVGKSCLLLRFADDTY-TESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIP---FLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC 205
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. UniProt/SwissProt
Match: sp|P35286|RAB13_RAT (Ras-related protein Rab-13 OS=Rattus norvegicus OX=10116 GN=Rab13 PE=1 SV=2)

HSP 1 Score: 145.976 bits (367), Expect = 1.338e-38
Identity = 73/168 (43.45%), Postives = 110/168 (65.48%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDM-VQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNL 2095
            + +FK++ IGDS VGKT +I RF  + F S  I STIG+DF+I+++ I    + LQ+WDTAGQERF++IT+ YYR + G+++VYDI  E S  N++ WM+++KE        L+L NKCDM  + +  R QA RL        + +F  SAK+  N++EAF  +A+++
Sbjct:    6 DHLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYI-STIGIDFKIRTVEIEGKRIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQREQAERLA---REHRIRFFETSAKSSVNVDEAFSSLARDI 169
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. UniProt/SwissProt
Match: sp|Q9DD03|RAB13_MOUSE (Ras-related protein Rab-13 OS=Mus musculus OX=10090 GN=Rab13 PE=1 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 4.155e-38
Identity = 72/168 (42.86%), Postives = 110/168 (65.48%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDM-VQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNL 2095
            + +FK++ IGDS VGKT +I RF  + F S  I STIG+DF+I+++ I    + LQ+WDTAGQERF++IT+ YYR + G+++VYDI  E S  N++ WM+++KE        L+L NKCDM  + +  R QA +L        + +F  SAK+  N++EAF  +A+++
Sbjct:    6 DHLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYI-STIGIDFKIRTVDIEGKRIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRQVQREQAEKLA---REHRIRFFETSAKSSVNVDEAFSSLARDI 169
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. UniProt/SwissProt
Match: sp|Q5KTJ6|RAB13_MESAU (Ras-related protein Rab-13 OS=Mesocricetus auratus OX=10036 GN=RAB13 PE=2 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 2.159e-37
Identity = 72/168 (42.86%), Postives = 109/168 (64.88%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVEN-VLYFHCSAKTGENINEAFQLMAKNL 2095
            + +FK++ IGDS VGKT +I RF  + F +  I STIG+DF+I+++ I    + LQ+WDTAGQERF++IT+ YYR + G+++VYDI  E S  N++ WM+++KE        L+L NKCDM   E  R       D L  E+ + +F  SAK+  N++EAF  +A+++
Sbjct:    6 DHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYI-STIGIDFKIRTVEIEGKRIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDM---EAKRKVLKEQADKLAREHGIRFFETSAKSSMNVDEAFNSLARDI 169
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. UniProt/SwissProt
Match: sp|Q58DS5|RAB13_BOVIN (Ras-related protein Rab-13 OS=Bos taurus OX=9913 GN=RAB13 PE=1 SV=1)

HSP 1 Score: 141.354 bits (355), Expect = 4.572e-37
Identity = 72/168 (42.86%), Postives = 109/168 (64.88%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVEN-VLYFHCSAKTGENINEAFQLMAKNL 2095
            + +FK++ IGDS VGKT +I RF  + F +  I STIG+DF+I+++ I    + LQ+WDTAGQERF++IT+ YYR + G+++VYDI  E S  N++ WM+++KE        L+L NKCDM   E  R       D L  E+ + +F  SAK+  N++EAF  +A+++
Sbjct:    6 DHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYI-STIGIDFRIRTVDIEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDM---EAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDI 169
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. UniProt/SwissProt
Match: sp|P51153|RAB13_HUMAN (Ras-related protein Rab-13 OS=Homo sapiens OX=9606 GN=RAB13 PE=1 SV=1)

HSP 1 Score: 141.354 bits (355), Expect = 4.617e-37
Identity = 72/168 (42.86%), Postives = 109/168 (64.88%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVEN-VLYFHCSAKTGENINEAFQLMAKNL 2095
            + +FK++ IGDS VGKT +I RF  + F +  I STIG+DF+I+++ I    + LQ+WDTAGQERF++IT+ YYR + G+++VYDI  E S  N++ WM+++KE        L+L NKCDM   E  R       D L  E+ + +F  SAK+  N++EAF  +A+++
Sbjct:    6 DHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYI-STIGIDFKIRTVDIEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDM---EAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDI 169
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. TrEMBL
Match: A0A0X3NZE8 (Ras and EF-hand domain-containing protein homolog OS=Schistocephalus solidus OX=70667 GN=RASEF PE=4 SV=1)

HSP 1 Score: 398.667 bits (1023), Expect = 1.085e-124
Identity = 263/691 (38.06%), Postives = 406/691 (58.76%), Query Frame = 2 
Query:  185 EDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDDLEFDDEGSSLNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEEKARK-LDKSNFSSSNGSM--DLYKELSM-AQEQSQ-----------PKVIDVADL------KKKRGSILSSYFVPKINVDQVSHERCQSMSYDDEDVLTDLGTSYNDFSYDAIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLGERSP---PDGAVEEVDIIK---GPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKEN---NDLKTAIKLDTKPKKGCC 2164
            E QAR+LY LCD E +GF+T+ED+ RL+D LP  +EQ ++VF+SLD D + +LT  EF+ G   +LG     P   + E     S  +   ++      +++   GL  D+++I+  W +L+N +  LL  FE LI  +  ++  +K EY  LE  LK + + ++EE++ LY+EM+ QIK E+ERLL +EK +EKEI+++LE  I+EKDKL  E+L+ H++T K+L+ L   ++E++Q++E L+ E+  LE +L  T+ +++DCQEYI+ L+KK++ +RR+RARAA+E++EGIALERE+LVRQL+ELRE N++L++E+    L +S+F+  + S    LY  + + +Q Q+            P ++D  D         +RGS + +YF       Q+      S          + G  + D   D++      +S     H                 L ++   L +RSP   PDGA+++  I++       PER+FKV+ IG+S VGKTSI++ F    F     A+TIGVD Q+K +++    V LQ+WDTAGQER+RSIT+ Y+RK+DGVV+VYD+ SE S + LR WM+NV + V+  T +++LANK D++      N   +  +    E   LYF  SAKTGENI+ AF+ + + L  +E+   NDL T        KK CC
Sbjct:   11 ERQARQLYKLCDPENRGFLTREDLARLSDVLPFTEEQLDAVFESLDQDGDEHLTYGEFLDGLGPYLGNKPLTPDSGEEENSRRDSHDDSEWEDSFRQSYQQLGEAGLLNDVESIRNVWKKLRNKSPTLLGDFEKLINALTKELTHSKTEYEGLEAALKKRISEHEEEVRHLYEEMETQIKQERERLLLQEKLKEKEIRESLEGRIKEKDKLLNELLRQHEETQKKLEQLEISYNEAAQKKEDLDNERIILERRLEETELNLKDCQEYIEVLSKKARDERRSRARAAMELSEGIALERETLVRQLNELRETNRRLRDERDEGLLRRSSFNQRSNSTGESLYAAMQLVSQGQTTVDGYGRMTAVCPNLVDRPDRFAANVHHGRRGSTMDTYF------SQIPTGALCSTGEGSIIEEEEAGDEFTDDVSDSV-----FSSRRKRSH-----------------LGNSARNLTDRSPRPSPDGAIDQATIMEDAFSGSGPERVFKVISIGNSGVGKTSILQMFVTGTFSQS--ATTIGVDVQVKPMKVDGTSVVLQLWDTAGQERYRSITTQYFRKADGVVLVYDLTSEMSFLQLRGWMQNVADGVDPGTPVMLLANKADLLNENVPANVTFQAGERFAKEYEALYFQVSAKTGENIDRAFEALVRCLKQQEDKRFNDLLTFKMPVLSKKKACC 671
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. TrEMBL
Match: A0A0B7BKP7 (EF-hand domain-containing protein OS=Arion vulgaris OX=1028688 GN=ORF195665 PE=4 SV=1)

HSP 1 Score: 376.711 bits (966), Expect = 1.153e-115
Identity = 268/721 (37.17%), Postives = 431/721 (59.78%), Query Frame = 2 
Query:  146 NQKIMSQAHHSIFEDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLG--APVEIPHD--DDLE---FDDEGSSLNQVAQEHL-EHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEEKARKLDKSNFSSSNGSMDLYKELSMAQEQSQPKVIDVADLKK--KRGSILSSYF----VPK----------INVDQVSHERCQSMSYDDEDVLTDLGTSY-----NDFSYDAIRVENNVTS-----SHNPIHSTSVALSPSYQEMEIQTLIDNEEK----------LGERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKL-DTKPKKGCCGR 2170
            NQ ++ Q    +   +A EL+ LCD+E+KGFITK DM RL   LP++ +Q E VFDSLDDD NG L+L+EF  GF  FLG  +P     D  D++E   ++ E  + +   +E +   +I  +    + +D + +K  W +L     ++ S FE  I  +  D+ K+K ++ +LE  L SKSN ++EE+K+LY+EM+LQIK EKER+L EE+ +E+  +  LE +++E++K  Q+IL  H +  ++L+NL+     + QE +RL+KE++ LE  L  +  ++ + + YI ++  + K ++R RARAA+ ++EGIA+ERESLV+QLD L+++NK+L+++K  + D ++    +G + L  E+  AQ  ++P+  +    K+  K+GS+LS+YF     P           ++VD +      S S+D E +    G S      N+    A+ V++ + S     S N         S S  ++ +     +E+K          + +RS P GA  +++    P KP+RIFKVVF+GDS VGK+S I RFC+ EF+    ++TIGVDFQIK++ + +  V LQ+WDTAGQERFRS+T  Y+RK+DG++++YD+  ES+  ++R WM +V+E VE  TVI++L NK D+ + +  R    +   +L VE ++L++  SAK+G  I E+ + +A  L  KE+  ++  +KL D KPKK CC R
Sbjct:   18 NQAMIDQMQE-VMSQKAVELFRLCDKEEKGFITKSDMQRLRAELPVSPDQLEVVFDSLDDDGNGFLSLQEFTDGFGSFLGLKSPNSSRDDNVDEMEPTMYEGEYGTTDPAMEEKMFTEMIHHIGASHIFQDEEVVKAMWLKLHREEPDMSSTFEEFIARLAGDIKKSKVDFLSLESALLSKSNEHEEEVKKLYEEMELQIKEEKERILAEERAKERHTRSELESQLKEREKQLQDILTKHQEMEQKLENLNKTDVMTKQENDRLQKERDMLEEMLGQSQNNLDESRSYIQQMQMQQKDEKRERARAALMLSEGIAIERESLVKQLDLLKDVNKKLRDDKD-EADATDI-RRDGPLSLDAEVKNAQ-GNEPQKSNSTPRKELHKQGSVLSNYFPGERAPHGRSTELVSVDLDVDGLYDGEDGSGSFDAESL---FGASVFIPDDNEDPEGALEVDDTIGSLGGQRSKNKNLRRQHHHSSSEDDVGLGEDGGSEDKKIKKVRAKLLMHKRSQPVGADSQIESY--PPKPQRIFKVVFVGDSGVGKSSFIHRFCHQEFKP-NFSTTIGVDFQIKTLDVKDSTVILQLWDTAGQERFRSMTKAYFRKADGIIVMYDVAVESTFTSVRNWMNSVQEHVEPGTVIMLLGNKLDISEDDAKRPVKQKDGLVLAVEWDMLFYETSAKSGTKITESMEALASLLQEKEDKKIEDGLKLTDDKPKKRCCRR 728
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. TrEMBL
Match: A0A2C9JD03 (EF-hand domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106051310 PE=4 SV=1)

HSP 1 Score: 366.696 bits (940), Expect = 7.439e-112
Identity = 263/705 (37.30%), Postives = 408/705 (57.87%), Query Frame = 2 
Query:  158 MSQAHHSIFEDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDDLEFDDE-----------GSSLNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEEKARKLDKSNFSSSNGSMDLYKELSMAQEQSQPKVIDVADLKK--KRGSILSSYF-------VPKINVDQVSHERCQSMSYD-DEDVLTDLGTSYNDFSYD----AIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLG-------ERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKL-DTKPKKGCCGR 2170
            M  +   +   +A EL+ LCD+E+KGFI K DM RL   LP++ +Q E VFDSLD+D NG LTLEEF  GF  FLG  +  P      +D+E           G +   + ++H + ++  +  V + +D D IK  W +L +   ++ S FE  I  + SD+ ++K ++ +LE  L SK+N +++E+K+LY+EM+LQIK E+E +L EEK +EK+++  LE ++ EK++   EIL  H +   +LQ L+ + + +  E ERL KEK ELE  L  + +++ + + YI ++  + K ++R RARAA+ ++EGIA+ERESLV+QLD L+++NK+L+++K    D++  + +        E S    + QP+       KK  K+GS+L  YF          ++VD    +  +    D D D L D        + D    A  +E   ++  + +H ++    PS    E    +   ++         +RS P GA +   +     KP+R+FKVVFIGDS VGK++II RFC+ EF+     +TIGVDFQ+K+I + +  V LQ+WDTAGQER+RS+T  Y+RK+DGV++VYD+ +ES+  N+R WM +VKE VE  TVI++L NK DM + +  R    +   LL  + ++L++  SAK+G NI EA       L  KE+  L+  +KL D+K KK CC R
Sbjct:   35 MLDSMQELMAQKAGELFRLCDKEEKGFINKSDMQRLRAELPVSPDQLEVVFDSLDNDGNGFLTLEEFTEGFGSFLG--IRSPSASREHYDEENEETTLYEGEAGVADPALEEKHFKEMLHHIGAVHVFQDEDIIKAMWQKLHHEEPDMASTFEEFIARMASDIKRSKVDFQSLEAALLSKNNEHEKEVKKLYEEMELQIKQEREIILMEEKAKEKQVRTELEQQLEEKERQLHEILTKHQELEHKLQKLNKVETLTKLENERLLKEKEELEEMLSQSQENLEESRNYIQQMQLQQKDEKRERARAALMLSEGIAIERESLVKQLDLLKDVNKKLRDDK----DEAEITEARRFQVKSVESSKPDHKPQPR-------KKICKQGSVLGKYFPGGSGRSTELVSVDLDMDDLAEVCGDDVDADELNDANVFIPGINEDEDDAASMIEEATSAPEDEVHLSTDQHHPSLSGGEKTGNVGGTKQKKRIKIRSLKRSQPVGA-DSFHMELAVPKPQRLFKVVFIGDSGVGKSTIIHRFCHQEFKC-NFQATIGVDFQVKTIELKDTIVILQLWDTAGQERYRSLTKTYFRKADGVIVVYDVTTESTFTNVRNWMTSVKEEVEPGTVIMLLGNKLDMAEDDAFRPVKEKDGRLLAEDTDMLFYETSAKSGINIKEAMDAFTSLLQEKEDKKLEEGLKLTDSKAKKRCCSR 724
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. TrEMBL
Match: A0A2C9JD09 (EF-hand domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106051310 PE=4 SV=1)

HSP 1 Score: 366.311 bits (939), Expect = 1.101e-111
Identity = 263/705 (37.30%), Postives = 411/705 (58.30%), Query Frame = 2 
Query:  158 MSQAHHSIFEDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDDLEFDDE-----------GSSLNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEEKARKLDKSNFSSSNGSMDL-YKELSMAQEQSQPKVIDVADLK-KKRGSILSSYF-------VPKINVDQVSHERCQSMSYD-DEDVLTDLGTSYNDFSYD----AIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLG-------ERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKL-DTKPKKGCCGR 2170
            M  +   +   +A EL+ LCD+E+KGFI K DM RL   LP++ +Q E VFDSLD+D NG LTLEEF  GF  FLG  +  P      +D+E           G +   + ++H + ++  +  V + +D D IK  W +L +   ++ S FE  I  + SD+ ++K ++ +LE  L SK+N +++E+K+LY+EM+LQIK E+E +L EEK +EK+++  LE ++ EK++   EIL  H +   +LQ L+ + + +  E ERL KEK ELE  L  + +++ + + YI ++  + K ++R RARAA+ ++EGIA+ERESLV+QLD L+++NK+L+++K    D++  + +   + L ++E   + E S+P        K  K+GS+L  YF          ++VD    +  +    D D D L D        + D    A  +E   ++  + +H ++    PS    E    +   ++         +RS P GA +   +     KP+R+FKVVFIGDS VGK++II RFC+ EF+     +TIGVDFQ+K+I + +  V LQ+WDTAGQER+RS+T  Y+RK+DGV++VYD+ +ES+  N+R WM +VKE VE  TVI++L NK DM + +  R    +   LL  + ++L++  SAK+G NI EA       L  KE+  L+  +KL D+K KK CC R
Sbjct:   35 MLDSMQELMAQKAGELFRLCDKEEKGFINKSDMQRLRAELPVSPDQLEVVFDSLDNDGNGFLTLEEFTEGFGSFLG--IRSPSASREHYDEENEETTLYEGEAGVADPALEEKHFKEMLHHIGAVHVFQDEDIIKAMWQKLHHEEPDMASTFEEFIARMASDIKRSKVDFQSLEAALLSKNNEHEKEVKKLYEEMELQIKQEREIILMEEKAKEKQVRTELEQQLEEKERQLHEILTKHQELEHKLQKLNKVETLTKLENERLLKEKEELEEMLSQSQENLEESRNYIQQMQLQQKDEKRERARAALMLSEGIAIERESLVKQLDLLKDVNKKLRDDK----DEAEITEARREVGLSFEEEVKSVESSKPDHKPQPRKKICKQGSVLGKYFPGGSGRSTELVSVDLDMDDLAEVCGDDVDADELNDANVFIPGINEDEDDAASMIEEATSAPEDEVHLSTDQHHPSLSGGEKTGNVGGTKQKKRIKIRSLKRSQPVGA-DSFHMELAVPKPQRLFKVVFIGDSGVGKSTIIHRFCHQEFKC-NFQATIGVDFQVKTIELKDTIVILQLWDTAGQERYRSLTKTYFRKADGVIVVYDVTTESTFTNVRNWMTSVKEEVEPGTVIMLLGNKLDMAEDDAFRPVKEKDGRLLAEDTDMLFYETSAKSGINIKEAMDAFTSLLQEKEDKKLEEGLKLTDSKAKKRCCSR 731
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. TrEMBL
Match: A0A2C9JD11 (EF-hand domain-containing protein OS=Biomphalaria glabrata OX=6526 GN=106051310 PE=4 SV=1)

HSP 1 Score: 365.925 bits (938), Expect = 1.275e-111
Identity = 263/705 (37.30%), Postives = 409/705 (58.01%), Query Frame = 2 
Query:  158 MSQAHHSIFEDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDDLEFDDE-----------GSSLNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEEKARKLDKSNFSSSNGSMDLYKELSMAQEQSQPKVIDVADLKK--KRGSILSSYF-------VPKINVDQVSHERCQSMSYD-DEDVLTDLGTSYNDFSYD----AIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLG-------ERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKL-DTKPKKGCCGR 2170
            M  +   +   +A EL+ LCD+E+KGFI K DM RL   LP++ +Q E VFDSLD+D NG LTLEEF  GF  FLG  +  P      +D+E           G +   + ++H + ++  +  V + +D D IK  W +L +   ++ S FE  I  + SD+ ++K ++ +LE  L SK+N +++E+K+LY+EM+LQIK E+E +L EEK +EK+++  LE ++ EK++   EIL  H +   +LQ L+ + + +  E ERL KEK ELE  L  + +++ + + YI ++  + K ++R RARAA+ ++EGIA+ERESLV+QLD L+++NK+L+++K    D++  + +     +  E S    + QP+       KK  K+GS+L  YF          ++VD    +  +    D D D L D        + D    A  +E   ++  + +H ++    PS    E    +   ++         +RS P GA +   +     KP+R+FKVVFIGDS VGK++II RFC+ EF+     +TIGVDFQ+K+I + +  V LQ+WDTAGQER+RS+T  Y+RK+DGV++VYD+ +ES+  N+R WM +VKE VE  TVI++L NK DM + +  R    +   LL  + ++L++  SAK+G NI EA       L  KE+  L+  +KL D+K KK CC R
Sbjct:   35 MLDSMQELMAQKAGELFRLCDKEEKGFINKSDMQRLRAELPVSPDQLEVVFDSLDNDGNGFLTLEEFTEGFGSFLG--IRSPSASREHYDEENEETTLYEGEAGVADPALEEKHFKEMLHHIGAVHVFQDEDIIKAMWQKLHHEEPDMASTFEEFIARMASDIKRSKVDFQSLEAALLSKNNEHEKEVKKLYEEMELQIKQEREIILMEEKAKEKQVRTELEQQLEEKERQLHEILTKHQELEHKLQKLNKVETLTKLENERLLKEKEELEEMLSQSQENLEESRNYIQQMQLQQKDEKRERARAALMLSEGIAIERESLVKQLDLLKDVNKKLRDDK----DEAEITEARRVKSV--ESSKPDHKPQPR-------KKICKQGSVLGKYFPGGSGRSTELVSVDLDMDDLAEVCGDDVDADELNDANVFIPGINEDEDDAASMIEEATSAPEDEVHLSTDQHHPSLSGGEKTGNVGGTKQKKRIKIRSLKRSQPVGA-DSFHMELAVPKPQRLFKVVFIGDSGVGKSTIIHRFCHQEFKC-NFQATIGVDFQVKTIELKDTIVILQLWDTAGQERYRSLTKTYFRKADGVIVVYDVTTESTFTNVRNWMTSVKEEVEPGTVIMLLGNKLDMAEDDAFRPVKEKDGRLLAEDTDMLFYETSAKSGINIKEAMDAFTSLLQEKEDKKLEEGLKLTDSKAKKRCCSR 722
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Cavefish
Match: cracr2ab (calcium release activated channel regulator 2Ab [Source:ZFIN;Acc:ZDB-GENE-041210-94])

HSP 1 Score: 173.326 bits (438), Expect = 1.045e-46
Identity = 126/408 (30.88%), Postives = 216/408 (52.94%), Query Frame = 2 
Query: 1049 MTEGIALERESLVRQLDELREINKQLQ-----------------EEKARKLDKSNFSSSNGSMDLYKELSMAQEQSQPKVI------DVADLKKKRGSILSSYFVPKINVDQVSHERCQSMSYDDEDVLTDLGTSYNDFSYDAIRVENNVTSSHNPIHSTSVALSPSY--QEMEIQTLIDNEE--KLGERSPPDG-AVEEVDIIKGPEK-----PERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASR-LKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP--KKGCC 2164
            +TEG+  E++SL++QLD L E+NK L+                 EE A+  D+   ++ NG        S +Q+ + P  +      D+ D   +   +     V  I  D + H     +  D   ++  L     +   +  ++E N++    PI+S++  L+ S+  +   ++ +   ++  K G  S P G  V +  + KGP +     PER+FKV+ +G+SSVGKT+ ++RFC+  F +   A+ I  D+ ++++ +G   VALQ+WDTAGQE +RSIT  ++RK+DGVV++YD+  +SS  ++  W+ +++EAV D   I++L NK DM   E  R   ++  K L    N++++ CSA TG N+ EA   +A  L  +E+   +  ++L  +P  KK CC
Sbjct:   44 ITEGLQREKQSLMKQLD-LLEMNKHLRDERDVSSLSVMAKEDKAEEPAQTPDQKPSTTVNGYGP--HTASGSQQNADPGTVAANSGQDLVDAPPEGWPLRR---VISIEEDHLPH----LLQGDPHPLIHQLSEEEKERGEEDAQIELNMS----PIYSSNAFLASSHSPRSSPVKKIFSKQKRGKGGVPSSPRGQPVGKETLQKGPPEGTVATPERLFKVILVGNSSVGKTAFLRRFCDGHFHATTTATVI--DYSVRTLNLGNSHVALQLWDTAGQE-YRSITKQFFRKADGVVVLYDVTMQSSFRSVHPWLVSIQEAVGDPIPIMLLGNKSDM---ESIRQVPTKEAKRLAEETNLMFYECSAYTGYNVLEAMLHLAV-LREQEDRVWENTVRLVDQPVKKKSCC 430
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Cavefish
Match: megf8 (ras-related protein Rab-8B [Source:NCBI gene;Acc:103041748])

HSP 1 Score: 141.354 bits (355), Expect = 6.729e-38
Identity = 71/175 (40.57%), Postives = 112/175 (64.00%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQAS--RLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDL 2119
            +FK++ IGDS VGKT ++ RF  + F +  I STIG+DF+I+++ +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI SE S  N++ W+ N++E    +   ++L NKCDM     ++ Q S  R + L     + +   SAKT  N+ EAF  +A+++ ++ N  +
Sbjct:    8 LFKLLLIGDSGVGKTCLLFRFSEDAFNTTFI-STIGIDFKIRTVELNGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITSEKSFENIKNWIRNIEEHASSDVERMILGNKCDM----NDKRQVSKERGEKLAIDYGIKFLETSAKTSVNVEEAFLTLARDIMSRLNRKM 177
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Cavefish
Match: rab13 (RAB13, member RAS oncogene family [Source:NCBI gene;Acc:103044636])

HSP 1 Score: 140.198 bits (352), Expect = 1.620e-37
Identity = 74/191 (38.74%), Postives = 120/191 (62.83%), Query Frame = 2 
Query: 1583 PEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVEN-VLYFHCSAKTGENINEAFQLMAKNL---TNKENNDLKTAIKLDT 2143
             +K + +FK++ IGDS VGKT +I RF  + F S  I STIG+DF++K+I +    V LQ+WDTAGQERF++IT+ YYR + G+++VYDI  E S  N++ WM+++KE        ++L NKCD+   E  R  +  + + L  ++ + +F  SAK+  N+ E+F  +A+++   + K++      +KL T
Sbjct:    2 AKKYDFLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYI-STIGIDFKVKTIEVEGKKVKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVSRMLLGNKCDI---EAKRKVSKEMGEKLAKDHGIRFFETSAKSSINVEESFMSLARDILLKSGKKSGPTGREVKLTT 188
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Cavefish
Match: ENSAMXT00000056277.1 (ras-related protein Rab-10-like [Source:NCBI gene;Acc:103035127])

HSP 1 Score: 139.813 bits (351), Expect = 1.822e-37
Identity = 73/190 (38.42%), Postives = 118/190 (62.11%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENR-NQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKPKKGCCG 2167
            +FK++ IGDS VGKT ++ RF ++ F +  I STIG+DF+IK++ +    + LQIWDTAGQERF +IT+ YYR + G+++VYDI +  S  N+ +W+ N++E   ++   ++L NKCDM   E+ R    ++ + + +  N+ +F  SAK   NI +AF ++A+++  K      T   +D   K G  G
Sbjct:    9 LFKLLLIGDSGVGKTCVLFRFSDDAFNTTFI-STIGIDFKIKTVELQGKRIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNAKSFENITKWLRNIEEHANEDVERMLLGNKCDM---EDMRVVPKAKGEQIASEHNIRFFETSAKANINIEKAFLMLAEDILRKTPGKETTNENVDVNSKSGSAG 194
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Cavefish
Match: rab1ba (zRAB1B, member RAS oncogene family a [Source:ZFIN;Acc:ZDB-GENE-040426-873])

HSP 1 Score: 140.198 bits (352), Expect = 2.516e-37
Identity = 72/202 (35.64%), Postives = 116/202 (57.43%), Query Frame = 2 
Query: 1589 KPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGE-ENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTA-----IKLDTKPKK----GCC 2164
            K + +FK++ IGDS VGK+ ++ RF ++ + +E   STIGVDF+I++I +    + LQIWDTAGQERFR+ITS YYR + G+++VYD+  + S  N++QW++ +     +    L++ NKCD+   +  +   A    D L +    +   SAK   N+ +AF  MA  +  +      T      +K+D+ P +    GCC
Sbjct:   25 KHDYLFKLLLIGDSGVGKSCLLLRFADDTY-TESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLAIP---FLETSAKNATNVEQAFMTMAAEIKKRMGPGATTGGDKPNLKIDSTPVRQSGGGCC 222
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Sea Lamprey
Match: rab1aa (RAB1A, member RAS oncogene family a [Source:ZFIN;Acc:ZDB-GENE-090312-110])

HSP 1 Score: 139.813 bits (351), Expect = 3.947e-38
Identity = 74/205 (36.10%), Postives = 119/205 (58.05%), Query Frame = 2 
Query: 1583 PEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGE-ENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNK------ENNDLKTAIKLDTKPKK----GCC 2164
            PE  + +FK++ IGDS VGK+ ++ RF ++ + +E   STIGVDF+I++I +    + LQIWDTAGQERFR+ITS YYR + G+++VYD+  + S  N++QW++ +     +    L++ NKCD+   +  +   A    D L +    +   SAK   N+ +AF  MA  +  +      +    K+ +K+D+ P K    GCC
Sbjct:    6 PEY-DYLFKLLLIGDSGVGKSCLLLRFADDTY-TESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLEIP---FLETSAKNATNVEQAFMTMAAEIKKRMGPGATQAGAGKSNVKIDSTPVKTGGGGCC 205
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Sea Lamprey
Match: rab8a (RAB8A, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-070424-36])

HSP 1 Score: 139.428 bits (350), Expect = 6.167e-38
Identity = 73/175 (41.71%), Postives = 112/175 (64.00%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLK-DLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDL 2119
            +FK++ IGDS VGKT ++ RF  + F S  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI +E S  N++ W+ N++E    +   ++L NKCDM      R Q +R + + L +E  + +   SAK   N+ EAF  +A+++  K +  L
Sbjct:    8 LFKLLLIGDSGVGKTCVLFRFSEDAFNSTFI-STIGIDFKIRTIDLDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFENIKNWIRNIEEHASADVEKMILGNKCDM----NERRQVTRERGEKLAIEYGIKFMETSAKASINVEEAFFTLARDIKAKMDRKL 177
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Sea Lamprey
Match: rasef (RAS and EF-hand domain containing [Source:ZFIN;Acc:ZDB-GENE-081105-157])

HSP 1 Score: 145.206 bits (365), Expect = 3.039e-36
Identity = 66/174 (37.93%), Postives = 110/174 (63.22%), Query Frame = 2 
Query: 1580 GPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCD---MVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAK 2089
             P   +R++K+V  GD++VGK+S + R C NEFR + IA T+GVDFQ+K++ +    + LQ+WDTAGQERFRSI   Y+R++DGV+++YD+  E + +N+R W++ ++++      ++++ NK D   M  G + +  A    + L +  N L+   SAK G N+ E    +A+
Sbjct:  563 APSHSDRVYKLVLAGDAAVGKSSFLLRLCRNEFRKDTIA-TLGVDFQMKTLIVDGEHMTLQLWDTAGQERFRSIAKSYFRRADGVLLLYDVTCEKTFLNVRDWIDIIEDSAPKSIPVMLVGNKSDMRNMSPGADQKYVAHTFGEKLAMNYNALFCETSAKDGSNVVETVLHLAR 735
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002219.1 (pep scaffold:Pmarinus_7.0:GL483980:50:9020:-1 gene:ENSPMAG00000002006.1 transcript:ENSPMAT00000002219.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.176 bits (313), Expect = 8.083e-33
Identity = 67/176 (38.07%), Postives = 97/176 (55.11%), Query Frame = 2 
Query: 1571 IIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVEN-VLYFHCSAKTGENINEAFQLMAKNL 2095
            +   P     IFK + IGD  VGK+ ++ +F   +F ++    TIGV+F  + I +    V LQIWDTAGQERFR++T  YYR + G +MVYDI   S+  +L  W+ + +      TVI ++ NK D+   E  R+           EN +L+   SAKTG+N+ EAF   AK +
Sbjct:    1 MAAAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMAD-CPHTIGVEFGTRIIEVSGQKVKLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIFLIGNKADL---EAQRDVTYEEAKQFAEENGLLFLEASAKTGDNVEEAFLETAKKI 172
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Sea Lamprey
Match: rab30 (RAB30, member RAS oncogene family [Source:ZFIN;Acc:ZDB-GENE-040718-250])

HSP 1 Score: 123.635 bits (309), Expect = 2.134e-32
Identity = 63/167 (37.72%), Postives = 93/167 (55.69%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEE-NRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLT 2098
            +FK+V IG++ VGKT +++RF    F   G  +TIGVDF IK++ +    + LQIWDTAGQERFRSIT  YYR +  +V+ YD+ SE +   L  W+  +++        +++ NK D+    +  R QA     L     + Y   SAK  EN+   F  +A+ L 
Sbjct:    9 LFKIVLIGNAGVGKTCLVRRFTQGLF-PPGQGATIGVDFMIKTVEVDGTKIKLQIWDTAGQERFRSITQSYYRSAHALVLTYDVSSEETFACLPAWLREMEQHASAHVPRVLVGNKLDLADVRQVTREQAEAFARL---HGLRYLETSAKEAENVERLFVELARRLA 171
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Yeast
Match: SEC4 (Rab family GTPase; essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane [Source:SGD;Acc:S000001889])

HSP 1 Score: 136.732 bits (343), Expect = 4.432e-37
Identity = 68/165 (41.21%), Postives = 102/165 (61.82%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAK 2089
            + I K++ IGDS VGK+ ++ RF  ++F    I +TIG+DF+IK++ I    V LQ+WDTAGQERFR+IT+ YYR + G+++VYD+  E +  N++QW + V E   DE  +L++ NK DM       +Q   L   L +    +   SAK  +N+NE F  +AK
Sbjct:   18 DSIMKILLIGDSGVGKSCLLVRFVEDKFNPSFI-TTIGIDFKIKTVDINGKKVKLQLWDTAGQERFRTITTAYYRGAMGIILVYDVTDERTFTNIKQWFKTVNEHANDEAQLLLVGNKSDMETRVVTADQGEALAKELGIP---FIESSAKNDDNVNEIFFTLAK 178
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Yeast
Match: YPT53 (Stress-induced Rab family GTPase; required for vacuolar protein sorting and endocytosis; involved in ionic stress tolerance; similar to Vps21p and Ypt52p; functional homolog of Vps21p; mammalian Rab5 homolog; YPT53 has a paralog, VPS21, that arose from the whole genome duplication [Source:SGD;Acc:S000005037])

HSP 1 Score: 132.109 bits (331), Expect = 2.181e-35
Identity = 69/178 (38.76%), Postives = 106/178 (59.55%), Query Frame = 2 
Query: 1592 PERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQG-EENRNQASR---LKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENN 2113
            P    KVV +G+S+VGK+SI+ RF +++F+ E    TIG  F  K I      +  +IWDTAGQERF  +   YYR +   ++V+D+ +E S    + W+E + E V  + VI ++ NK D++   +EN N+A +   +++L   EN+LYF  SAKTGENI + FQ + + +   E N
Sbjct:    9 PTLTIKVVLLGESAVGKSSIVLRFVSDDFK-ESKEPTIGAAFLTKRITRDGKVIKFEIWDTAGQERFAPLAPMYYRNAQAALVVFDVTNEGSFYKAQNWVEELHEKVGHDIVIALVGNKMDLLNNDDENENRAMKAPAVQNLCERENLLYFEASAKTGENIYQIFQTLGEKVPCPEQN 185
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Yeast
Match: VPS21 (Endosomal Rab family GTPase; required for endocytic transport and sorting of vacuolar hydrolases; required for endosomal localization of the CORVET complex; required with YPT52 for MVB biogenesis and sorting; involved in autophagy and ionic stress tolerance; geranylgeranylation required for membrane association; protein abundance increases in response to DNA replication stress; mammalian Rab5 homolog; VPS21 has a paralog, YPT53, that arose from the whole genome duplication [Source:SGD;Acc:S000005615])

HSP 1 Score: 128.257 bits (321), Expect = 3.554e-34
Identity = 62/157 (39.49%), Postives = 96/157 (61.15%), Query Frame = 2 
Query: 1607 KVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQ-GEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAF 2074
            K+V +G+++VGK+SI+ RF +N+F +E    TIG  F  + + I E+ V  +IWDTAGQERF S+   YYR +   ++VYD+    S I  R W++ + E    + +I ++ NK DM+Q G E +      + L   + +L+F  SAKTGEN+N+ F
Sbjct:    9 KLVLLGEAAVGKSSIVLRFVSNDF-AENKEPTIGAAFLTQRVTINEHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKDIIIALVGNKIDMLQEGGERKVAREEGEKLAEEKGLLFFETSAKTGENVNDVF 164
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Yeast
Match: YPT1 (Rab family GTPase; involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by type II protein geranylgeranyltransferase (Bet2p-Bet4p); binds to unspliced HAC1 mRNA; regulates the unfolded protein response (UPR) by promoting the decay of HAC1 RNA; localizes to the early Golgi, the transitional Golgi and ER membranes, pre-autophagosomal structures, and cytoplasmic vesicles [Source:SGD;Acc:S000001856])

HSP 1 Score: 124.79 bits (312), Expect = 4.998e-33
Identity = 60/167 (35.93%), Postives = 103/167 (61.68%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNL 2095
            + +FK++ IG+S VGK+ ++ RF ++ + ++ I STIGVDF+IK++ +    V LQIWDTAGQERFR+ITS YYR S G+++VYD+  + S   ++ W++ +        + L++ NKCD+   ++   +    K+  +   + +   SA    N+ +AF  MA+ +
Sbjct:    6 DYLFKLLLIGNSGVGKSCLLLRFSDDTYTNDYI-STIGVDFKIKTVELDGKTVKLQIWDTAGQERFRTITSSYYRGSHGIIIVYDVTDQESFNGVKMWLQEIDRYATSTVLKLLVGNKCDL--KDKRVVEYDVAKEFADANKMPFLETSALDSTNVEDAFLTMARQI 169
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Yeast
Match: YPT31 (Rab family GTPase; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi; YPT31 has a paralog, YPT32, that arose from the whole genome duplication; localizes to the transitional and late Golgi [Source:SGD;Acc:S000000833])

HSP 1 Score: 122.479 bits (306), Expect = 5.426e-32
Identity = 62/159 (38.99%), Postives = 94/159 (59.12%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQ 2077
            +FK+V IGDS VGK++++ RF  NEF  +   STIGV+F  +++ I    +  QIWDTAGQER+R+ITS YYR + G ++VYDI   SS  N   W+  ++E  +D   + ++ NK D+        + S  K       +L+   SA   EN+++AF+
Sbjct:   13 LFKIVLIGDSGVGKSNLLSRFTKNEFNMDS-KSTIGVEFATRTLEIDGKRIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLSELRENADDNVAVGLIGNKSDLAHLRAVPTEES--KTFAQENQLLFTETSALNSENVDKAFE 168
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Nematostella
Match: EDO28399 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL89])

HSP 1 Score: 167.933 bits (424), Expect = 2.139e-48
Identity = 80/163 (49.08%), Postives = 114/163 (69.94%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENR-NQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMA 2086
            +FKVVFIGDS VGK+S + RFC+++++     +TIGVDFQIK++ +    +A+Q+WDTAGQERFRSIT  Y+RK+DG+++ YD+ +ESS  NL+ WM +V+E  E+    +VL NK D+ + EE+R  +    K+L N  + LY   SAKTG NI EA   +A
Sbjct:    1 VFKVVFIGDSGVGKSSFLHRFCHDQWKPS-FTATIGVDFQIKTMNVNGQCIAIQLWDTAGQERFRSITKQYFRKADGILIFYDVTAESSFTNLKSWMVSVEEGAEEGVAKMVLGNKTDLAEDEESRVVKTIDGKNLANQYDALYMETSAKTGNNIQEAMYKLA 162
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Nematostella
Match: EDO47822 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL89])

HSP 1 Score: 167.933 bits (424), Expect = 2.139e-48
Identity = 80/163 (49.08%), Postives = 114/163 (69.94%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENR-NQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMA 2086
            +FKVVFIGDS VGK+S + RFC+++++     +TIGVDFQIK++ +    +A+Q+WDTAGQERFRSIT  Y+RK+DG+++ YD+ +ESS  NL+ WM +V+E  E+    +VL NK D+ + EE+R  +    K+L N  + LY   SAKTG NI EA   +A
Sbjct:    1 VFKVVFIGDSGVGKSSFLHRFCHDQWKPS-FTATIGVDFQIKTMNVNGQCIAIQLWDTAGQERFRSITKQYFRKADGILIFYDVTAESSFTNLKSWMVSVEEGAEEGVAKMVLGNKTDLAEDEESRVVKTIDGKNLANQYDALYMETSAKTGNNIQEAMYKLA 162
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Nematostella
Match: EDO47471 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMA6])

HSP 1 Score: 147.902 bits (372), Expect = 1.031e-40
Identity = 82/197 (41.62%), Postives = 123/197 (62.44%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLK--DLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENN----DLKTAIKL-DTKPKK-GCCG 2167
            +FK++ IGDS VGKT I+ RF ++ F +  I STIG+DF+IK+I +    + LQIWDTAGQERF +IT+ YYR + G+++VYDI  E +  N+ +W+ N++E   ++   ++L NKCDM    ++R   SR +   +     + +   SAKT  NI +AFQ +A+++  KE N    +    I + D K KK GCCG
Sbjct:    9 LFKLLLIGDSGVGKTCILFRFSDDAFNTTFI-STIGIDFKIKTIEMQGKKIKLQIWDTAGQERFHTITTSYYRGAMGIMLVYDITQEKTFDNISKWLRNIEEHANEDVEKMILGNKCDM----DDRRIVSRERGEQIAREHGIRFLETSAKTNINIEQAFQYLAQDILKKELNKDSEEPSNNIHVHDQKDKKGGCCG 200
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Nematostella
Match: EDO47990 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKI3])

HSP 1 Score: 142.895 bits (359), Expect = 8.052e-39
Identity = 78/210 (37.14%), Postives = 122/210 (58.10%), Query Frame = 2 
Query: 1580 GPEKPE--RIF----KVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMV-QGEENRNQASRL-KDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDT-------KPKKGCC 2164
            GP K +   +F    KV+ +GDS VGKT ++ RF +  F S    ST+G+D++ K + +    V LQIWDTAGQERFRSIT  YYR S  ++++YD+ + +S  N+R W+  + E    + +I++LANK D+  Q   +R+Q  +L KD     NV +   SAKTG N++ AF  +A+++ ++E N      + +        + + GCC
Sbjct:    9 GPTKRQTGEVFDVACKVMLLGDSGVGKTCLLVRFKDGAFLSGSFISTVGIDYKNKVVEVDGSKVKLQIWDTAGQERFRSITHAYYRDSHALLLLYDVTNHASFENIRAWLAEIYEYARQDVIIMLLANKADLTKQRVVSRDQGEKLAKD----HNVAFMETSAKTGLNVDLAFMAIARDIKHREANSTTADPQFNIGQYVESQRERPGCC 214
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Nematostella
Match: EDO41018 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5I6])

HSP 1 Score: 142.124 bits (357), Expect = 1.268e-38
Identity = 75/175 (42.86%), Postives = 114/175 (65.14%), Query Frame = 2 
Query: 1601 IFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLK-DLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDL 2119
            +FK++ IGDS VGKT ++ RF  + F S  I STIG+DF+I++I +    + LQIWDTAGQERFR+IT+ YYR + G+++VYDI ++ S  N++ W+ N++E    +   +VL NKCDM    E+R Q S+ + + L VE  + +   SAK   N+ EAF  +A+++  K +  L
Sbjct:    8 LFKLLLIGDSGVGKTCVLFRFSEDAFNSTFI-STIGIDFKIRTIELDGKKIKLQIWDTAGQERFRTITTAYYRGAMGIMLVYDITNDKSFENIKNWIRNIEEHASQDVEKMVLGNKCDM----EDRRQVSKERGEQLAVEYGIKFMETSAKASINVEEAFFTLARDIKLKMDKKL 177
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Medaka
Match: ENSORLT00000027276.1 (calcium release activated channel regulator 2A [Source:NCBI gene;Acc:101161971])

HSP 1 Score: 276.944 bits (707), Expect = 9.208e-82
Identity = 221/695 (31.80%), Postives = 352/695 (50.65%), Query Frame = 2 
Query:  200 ELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDD-------LEFDDEGSS--LNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEE-----------------KAR------KLDKSNFSSSNGSMDLYKELSMAQEQSQPKVIDVADLKKKRGSILSSYFVPKINVDQVSH---ERCQSMSYDDEDVLTDLGTS-YNDFSYDAIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLGERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVL-YFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP---KKGCC 2164
            E + +CD E KGFI + DM RL   LPL++ + E+VFD LD D+NG LTLEEF  GFS FL      P   D        E  +EG +       +EH   L+E++      ED   ++  W  L+    +LLS+FE  +  + S + KA  E   +E  L+ K+  +D+E++ LY+EM+ QIK E++R++ ++ +R      +LE+++  K+K  +++ +   K   + Q L      +  E  +L++   ELE +L+   + +   QE ++ L ++S +    +      +TEG+  +R SL++QLD LRE+NK L++E                 K R      K+  + F  S    +    LS     SQP +  V     +R  I+S      I  D + H    R    S  + D + DL +    DF Y       N ++  N      +  SP  Q +  +T I+ E                     P  P+R+FKVV +G+SSVGKT  ++RFC++ F   G  +T+GVD+ +K++ +    VALQ+WDTAGQER+RSIT  ++RK+DGVV++YDI +E S   +RQW+ +VKE+  +E  I++L NK D    E  R    ++ + L  +  L  F CSA +GEN+ E+   +A+ L  +E+ + +  + L   P   K+ CC
Sbjct:   53 EFFQMCDLENKGFINRRDMQRLNGELPLSENELENVFDCLDSDSNGFLTLEEFSSGFSAFLHGQSVDPSTKDGNPCKILPEVWEEGPTREDEYEEEEHFSVLMERLGANNAFEDPAEVRSLWAHLRRDEPQLLSNFEDFLARVTSQIMKANQEKKEMECALEKKAAKHDDEIQHLYEEMEQQIKNEQDRIVLQDYERFLSRSRDLELQLSNKEKELEQLFQKQRKLEFQCQELHGKQHVTKVENMKLKQSNGELERELQYVSQKLMFAQEQLELLQEQSSKLHEEKEMEVYRVTEGLHRDRASLLKQLDLLREMNKHLRDERDMVHHKPKNSLRRATLKQRPSVDELKVSNAEFPRSEDE-EAETRLSSKNASSQPCLSAVPGRHLRR--IIS------IEEDHLPHLVNYRSSPNSLQESDGVDDLCSEEMEDFVYP------NTSAEENGETERQMPTSPRVQPVGKETSINEE-------------------SAPSAPDRLFKVVLVGNSSVGKTCFLRRFCDDCFHP-GTCATVGVDYSVKTLTVDNSQVALQLWDTAGQERYRSITKQFFRKADGVVVMYDITAEQSFTAVRQWLSSVKESANEEIPIMLLGNKTD---KEMERKVEKKMGERLAKDCQLSVFECSAYSGENVLESMVHLARILKKQEDQEKEKTVLLVGGPSARKRSCC 709
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Medaka
Match: ENSORLT00000035474.1 (calcium release activated channel regulator 2A [Source:NCBI gene;Acc:101161971])

HSP 1 Score: 276.944 bits (707), Expect = 9.208e-82
Identity = 221/695 (31.80%), Postives = 352/695 (50.65%), Query Frame = 2 
Query:  200 ELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDD-------LEFDDEGSS--LNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEE-----------------KAR------KLDKSNFSSSNGSMDLYKELSMAQEQSQPKVIDVADLKKKRGSILSSYFVPKINVDQVSH---ERCQSMSYDDEDVLTDLGTS-YNDFSYDAIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLGERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVL-YFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP---KKGCC 2164
            E + +CD E KGFI + DM RL   LPL++ + E+VFD LD D+NG LTLEEF  GFS FL      P   D        E  +EG +       +EH   L+E++      ED   ++  W  L+    +LLS+FE  +  + S + KA  E   +E  L+ K+  +D+E++ LY+EM+ QIK E++R++ ++ +R      +LE+++  K+K  +++ +   K   + Q L      +  E  +L++   ELE +L+   + +   QE ++ L ++S +    +      +TEG+  +R SL++QLD LRE+NK L++E                 K R      K+  + F  S    +    LS     SQP +  V     +R  I+S      I  D + H    R    S  + D + DL +    DF Y       N ++  N      +  SP  Q +  +T I+ E                     P  P+R+FKVV +G+SSVGKT  ++RFC++ F   G  +T+GVD+ +K++ +    VALQ+WDTAGQER+RSIT  ++RK+DGVV++YDI +E S   +RQW+ +VKE+  +E  I++L NK D    E  R    ++ + L  +  L  F CSA +GEN+ E+   +A+ L  +E+ + +  + L   P   K+ CC
Sbjct:   53 EFFQMCDLENKGFINRRDMQRLNGELPLSENELENVFDCLDSDSNGFLTLEEFSSGFSAFLHGQSVDPSTKDGNPCKILPEVWEEGPTREDEYEEEEHFSVLMERLGANNAFEDPAEVRSLWAHLRRDEPQLLSNFEDFLARVTSQIMKANQEKKEMECALEKKAAKHDDEIQHLYEEMEQQIKNEQDRIVLQDYERFLSRSRDLELQLSNKEKELEQLFQKQRKLEFQCQELHGKQHVTKVENMKLKQSNGELERELQYVSQKLMFAQEQLELLQEQSSKLHEEKEMEVYRVTEGLHRDRASLLKQLDLLREMNKHLRDERDMVHHKPKNSLRRATLKQRPSVDELKVSNAEFPRSEDE-EAETRLSSKNASSQPCLSAVPGRHLRR--IIS------IEEDHLPHLVNYRSSPNSLQESDGVDDLCSEEMEDFVYP------NTSAEENGETERQMPTSPRVQPVGKETSINEE-------------------SAPSAPDRLFKVVLVGNSSVGKTCFLRRFCDDCFHP-GTCATVGVDYSVKTLTVDNSQVALQLWDTAGQERYRSITKQFFRKADGVVVMYDITAEQSFTAVRQWLSSVKESANEEIPIMLLGNKTD---KEMERKVEKKMGERLAKDCQLSVFECSAYSGENVLESMVHLARILKKQEDQEKEKTVLLVGGPSARKRSCC 709
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Medaka
Match: ENSORLT00000046122.1 (calcium release activated channel regulator 2A [Source:NCBI gene;Acc:101161971])

HSP 1 Score: 276.944 bits (707), Expect = 9.208e-82
Identity = 221/695 (31.80%), Postives = 352/695 (50.65%), Query Frame = 2 
Query:  200 ELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDD-------LEFDDEGSS--LNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEE-----------------KAR------KLDKSNFSSSNGSMDLYKELSMAQEQSQPKVIDVADLKKKRGSILSSYFVPKINVDQVSH---ERCQSMSYDDEDVLTDLGTS-YNDFSYDAIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLGERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVL-YFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP---KKGCC 2164
            E + +CD E KGFI + DM RL   LPL++ + E+VFD LD D+NG LTLEEF  GFS FL      P   D        E  +EG +       +EH   L+E++      ED   ++  W  L+    +LLS+FE  +  + S + KA  E   +E  L+ K+  +D+E++ LY+EM+ QIK E++R++ ++ +R      +LE+++  K+K  +++ +   K   + Q L      +  E  +L++   ELE +L+   + +   QE ++ L ++S +    +      +TEG+  +R SL++QLD LRE+NK L++E                 K R      K+  + F  S    +    LS     SQP +  V     +R  I+S      I  D + H    R    S  + D + DL +    DF Y       N ++  N      +  SP  Q +  +T I+ E                     P  P+R+FKVV +G+SSVGKT  ++RFC++ F   G  +T+GVD+ +K++ +    VALQ+WDTAGQER+RSIT  ++RK+DGVV++YDI +E S   +RQW+ +VKE+  +E  I++L NK D    E  R    ++ + L  +  L  F CSA +GEN+ E+   +A+ L  +E+ + +  + L   P   K+ CC
Sbjct:   53 EFFQMCDLENKGFINRRDMQRLNGELPLSENELENVFDCLDSDSNGFLTLEEFSSGFSAFLHGQSVDPSTKDGNPCKILPEVWEEGPTREDEYEEEEHFSVLMERLGANNAFEDPAEVRSLWAHLRRDEPQLLSNFEDFLARVTSQIMKANQEKKEMECALEKKAAKHDDEIQHLYEEMEQQIKNEQDRIVLQDYERFLSRSRDLELQLSNKEKELEQLFQKQRKLEFQCQELHGKQHVTKVENMKLKQSNGELERELQYVSQKLMFAQEQLELLQEQSSKLHEEKEMEVYRVTEGLHRDRASLLKQLDLLREMNKHLRDERDMVHHKPKNSLRRATLKQRPSVDELKVSNAEFPRSEDE-EAETRLSSKNASSQPCLSAVPGRHLRR--IIS------IEEDHLPHLVNYRSSPNSLQESDGVDDLCSEEMEDFVYP------NTSAEENGETERQMPTSPRVQPVGKETSINEE-------------------SAPSAPDRLFKVVLVGNSSVGKTCFLRRFCDDCFHP-GTCATVGVDYSVKTLTVDNSQVALQLWDTAGQERYRSITKQFFRKADGVVVMYDITAEQSFTAVRQWLSSVKESANEEIPIMLLGNKTD---KEMERKVEKKMGERLAKDCQLSVFECSAYSGENVLESMVHLARILKKQEDQEKEKTVLLVGGPSARKRSCC 709
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Medaka
Match: cracr2ab (ras and EF-hand domain-containing protein homolog [Source:NCBI gene;Acc:101155481])

HSP 1 Score: 163.31 bits (412), Expect = 2.268e-41
Identity = 77/195 (39.49%), Postives = 122/195 (62.56%), Query Frame = 2 
Query: 1592 PERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVE-NVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTK---PKKGCC 2164
            P+R+FKVV +GDS VGKTS+++ FC   F      +T+G+D+ +K++ +    +A+Q+WDTAGQER+RSIT  ++RK+DGVV+++D+  E S   +R W+ NV+EA  +   IL+L NK DM   E+ R  + +  + L  E N++++  SA TG N+ E+   +A+ L  +E+    T + L       KK CC
Sbjct:  577 PDRLFKVVLVGDSCVGKTSLLRSFCEGRFHPSS-TTTVGIDYSVKTLTLDSIQIAMQLWDTAGQERYRSITKQFFRKADGVVVMFDVTLEESFKAVRPWLNNVQEAAGEGIPILLLGNKMDM---EQEREVSFKAAERLAFENNMMFYEVSAYTGMNVTESLTHLARVLIEQEDRVRDTTVTLTAAHPIKKKTCC 767

HSP 2 Score: 127.872 bits (320), Expect = 5.252e-30
Identity = 102/332 (30.72%), Postives = 176/332 (53.01%), Query Frame = 2 
Query:  191 QARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFL-GAPVEIPHDD---------------DLEFDDEGSSLNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELREINKQLQEEK 1138
            + +E +  CD E KGF+T+ DM RL   +PL+ E+ E VFDSLD D+ G LTLE F   FS+FL G  + +  D                  +++ + S      + H   L+E +  + + ED   ++  W Q +     LLS+FE  +  +   + +A  E   +E  L+ K+  +D E++ LY+EM+ QIK EKERLL  + +R +    +LE ++R K++  + + +   +   +   L+    ES  E  +L+   +EL   L  T + +   QE +  L +++++ ++ +      +TEG+  E++SL+RQLD LRE+NK L++E+
Sbjct:   30 KTKEFFQTCDVEGKGFLTRLDMRRLHREVPLSAEELEDVFDSLDMDHAGYLTLEAFSSRFSQFLHGRRISVTDDQHQASGPVLKTKEALYQSQWEAKLSGDEDEEERHFCMLLESLGAINVFEDPGEVQNLWTQFRRDEPHLLSNFEEFLARVTVQIKEAYQEKKEMESALQRKAATHDSEIRHLYEEMEAQIKTEKERLLLMDSERLQLRSQDLEHQLRSKERELEYLFQKQKRLELQCNELNSEKQESHVENLKLKMTNDELSKALECTGQELALAQEQLAMLQEQARRLQQEKEMEMYRVTEGLQREKQSLMRQLDLLREMNKHLKDER 361
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Medaka
Match: rasef (RAS and EF-hand domain containing [Source:NCBI gene;Acc:101171009])

HSP 1 Score: 156.377 bits (394), Expect = 5.154e-39
Identity = 79/197 (40.10%), Postives = 123/197 (62.44%), Query Frame = 2 
Query: 1595 ERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAF----QLMAKNLTNKENNDLKTAIKLD---TKPKKGCC 2164
            E+ +++V  GD++VGK+S + R C NEF+    A T+GVDF +K++ +    V LQ+WDTAGQERFRSI   Y+R++DGV+++YD+  E S +N+R+W++ +++   ++  I+++ NKCDM + E N    S  + L    N L+   SAK G NI EA     +L+ K+ T +E    ++   LD   TKPK  CC
Sbjct:  626 EKAYRIVLAGDAAVGKSSFLLRLCKNEFQLNSSA-TLGVDFHMKTLIVDGEPVLLQLWDTAGQERFRSIAKSYFRRADGVLLLYDVTCEKSFLNIREWVDMIEDVSHEDIPIMLVGNKCDMRKEEFNCVPISYGEKLAMTYNTLFCETSAKDGSNILEAVLHLARLVKKHATFEEKRRGQSLPSLDAPRTKPKHLCC 821
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Planmine SMEST
Match: SMESG000049749.1 (SMESG000049749.1)

HSP 1 Score: 629.017 bits (1621), Expect = 0.000e+0
Identity = 301/302 (99.67%), Postives = 301/302 (99.67%), Query Frame = 2 
Query: 1184 MDLYKELSMAQEQSQPKVIDVADLKKKRGSILSSYFVPKINVDQVSHERCQSMSYDDEDVLTDLGTSYNDFSYDAIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLGERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAK 2089
            MDLYKELSMAQEQSQPKVIDVADLKKKRGSILSSYFVPKINVDQVSHERCQSMSYDDED LTDLGTSYNDFSYDAIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLGERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAK
Sbjct:    1 MDLYKELSMAQEQSQPKVIDVADLKKKRGSILSSYFVPKINVDQVSHERCQSMSYDDEDALTDLGTSYNDFSYDAIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTLIDNEEKLGERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAK 302
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Planmine SMEST
Match: SMESG000049774.1 (SMESG000049774.1)

HSP 1 Score: 553.518 bits (1425), Expect = 0.000e+0
Identity = 314/317 (99.05%), Postives = 316/317 (99.68%), Query Frame = 2 
Query:  158 MSQAHHSIFEDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDDLEFDDEGSSLNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIXXXXXXXXXXXXXXXXXXXDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQXXXXXXXXXXXXXXXXXVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTEGIALERESLVRQLDELR 1108
            MSQAHHSIFEDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDDLEFDDEGSSLNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYN+LEGVLKSKSNIYDEEMKRLYDEMDLQIKAEKERLL EEKKREKEIKDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQERERLEKEKNELENKLRVTDKSVRDCQEYIDELNKKSKQDRRNRA+AAIEMTEGIALERESLVRQLDELR
Sbjct:    1 MSQAHHSIFEDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESVFDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDDLEFDDEGSSLNQVAQEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIISDMHKAKNEYNSLEGVLKSKSNIYDEEMKRLYDEMDLQIKAEKERLLIEEKKREKEIKDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQERERLEKEKNELENKLRVTDKSVRDCQEYIDELNKKSKQDRRNRAKAAIEMTEGIALERESLVRQLDELR 317
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Planmine SMEST
Match: SMESG000043201.1 (SMESG000043201.1)

HSP 1 Score: 199.904 bits (507), Expect = 8.687e-58
Identity = 104/249 (41.77%), Postives = 155/249 (62.25%), Query Frame = 2 
Query: 1433 SSHNPIHSTSVALSP-SYQEMEIQTLIDNEEKLGERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP--KKGCCGR 2170
            +S   + +  +  SP  Y+E+++QT  + +++     P D  ++   I  G E PE +FKVV +GDS+VGK++I+ RFCN  FR E   +TIGVDF +KSI +    +ALQ+WDTAGQER+ SIT  +YRK+DGV++VYDI+   S IN+R W++NV++   DE ++++L NK D+ + +          DL      L F  SA TGENINE+F  +AK L  +++ D+  A +L TKP  K  CC +
Sbjct:   42 ASLGSVQTNIIVASPVKYREIDVQTEQEEKKETAVEKPID--IQYKLIFSGEEMPESVFKVVLVGDSNVGKSAILDRFCNGTFR-ENYRNTIGVDFMLKSIEVENIIIALQLWDTAGQERYESITKQFYRKTDGVILVYDIMETGSFINIRNWIDNVEKNTGDEVMLMMLGNKLDLAKSQPKAIPTKNACDLSREYGALMFEVSALTGENINESFATLAKVLKLRQDVDINNAFQL-TKPSNKSSCCCK 286
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Planmine SMEST
Match: SMESG000039353.1 (SMESG000039353.1)

HSP 1 Score: 187.193 bits (474), Expect = 2.286e-54
Identity = 92/195 (47.18%), Postives = 129/195 (66.15%), Query Frame = 2 
Query: 1592 PERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP--KKGCCGR 2170
            PE +FKVV +GDS+VGK++I+ RFCN  FR E   +TIGVDF +KSI +    +ALQ+WDTAGQER+ SIT  +YRK+DGV++VYDI+   S IN+R W++NV++   DE ++++L NK D+ + +          DL      L F  SA TGENINE+F  +AK L  +++ D+  A +L TKP  K  CC +
Sbjct:    2 PESVFKVVLVGDSNVGKSAILDRFCNGTFR-ENYRNTIGVDFMLKSIEVENIIIALQLWDTAGQERYESITKQFYRKTDGVILVYDIMETGSFINIRNWIDNVEKNTGDEVMLMMLGNKLDLAKSQPKAIPTKNACDLSREYGALMFEVSALTGENINESFATLAKVLKLRQDVDINNAFQL-TKPSNKSSCCCK 194
[Close]
BLAST of Ras and EF-hand domain-containing protein homolog vs. Planmine SMEST
Match: SMESG000040702.1 (SMESG000040702.1)

HSP 1 Score: 168.703 bits (426), Expect = 8.875e-48
Identity = 86/195 (44.10%), Postives = 123/195 (63.08%), Query Frame = 2 
Query: 1592 PERIFKVVFIGDSSVGKTSIIKRFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITSHYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDMVQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKENNDLKTAIKLDTKP--KKGCCGR 2170
            PE +FKVV +GDS+VGK++I+  F       E   +TIGVDF +KSI +    +ALQ+WDTAGQE + SIT  +YRK+DGV++VYDI+   S IN+R W++NV++   DE ++++L NK D+ + +          DL      L F  SA TGENINE+F  +AK L  +++ D+  A +L TKP  K  CC +
Sbjct:    2 PESVFKVVLVGDSNVGKSAILDTF------RENYRNTIGVDFMLKSIEVENIIIALQLWDTAGQEIYESITKQFYRKTDGVILVYDIMETRSFINIRNWIDNVEKNTGDEVMLMMLGNKLDLAKSQPKAIPTKNACDLSREYGALMFEVSALTGENINESFATLAKVLKLRQDVDINNAFQL-TKPSNKSSCCCK 189
The following BLAST results are available for this feature:
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CRACR2A1.654e-6328.81calcium release activated channel regulator 2A [So... [more]
AL358472.69.614e-3842.86novel protein[more]
RAB139.614e-3842.86RAB13, member RAS oncogene family [Source:HGNC Sym... [more]
RAB8B4.465e-3740.57RAB8B, member RAS oncogene family [Source:HGNC Sym... [more]
RAB8B1.017e-3640.57RAB8B, member RAS oncogene family [Source:HGNC Sym... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
4R79.23.600e-5345.45pep chromosome:WBcel235:IV:17480396:17482329:-1 ge... [more]
4R79.22.886e-5245.45pep chromosome:WBcel235:IV:17480396:17483332:-1 ge... [more]
rab-82.042e-3740.45RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5E... [more]
rab-82.042e-3740.45RAB family; Rab8 [Source:UniProtKB/TrEMBL;Acc:G5E... [more]
rsef-12.556e-3633.20Ras and EF-hand domain-containing protein homolog ... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rab81.365e-3540.24gene:FBgn0262518 transcript:FBtr0308833[more]
Rab81.365e-3540.24gene:FBgn0262518 transcript:FBtr0074921[more]
Rab192.502e-3538.38gene:FBgn0015793 transcript:FBtr0331832[more]
Rab192.502e-3538.38gene:FBgn0015793 transcript:FBtr0076705[more]
Rab13.503e-3535.82gene:FBgn0285937 transcript:FBtr0084104[more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cracr2ab1.095e-4942.27calcium release activated channel regulator 2Ab [S... [more]
cracr2ab3.489e-4842.27calcium release activated channel regulator 2Ab [S... [more]
CABZ01062083.11.123e-4239.69calcium release activated channel regulator 2Aa [S... [more]
rab139.582e-3841.24RAB13, member RAS oncogene family [Source:NCBI gen... [more]
megf89.924e-3842.17multiple EGF-like-domains 8 [Source:ZFIN;Acc:ZDB-G... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pknox29.776e-3840.78PBX/knotted 1 homeobox 2 [Source:Xenbase;Acc:XB-GE... [more]
irf61.111e-3634.72interferon regulatory factor 6 [Source:Xenbase;Acc... [more]
erich32.018e-3631.09glutamate rich 3 [Source:Xenbase;Acc:XB-GENE-58807... [more]
erich32.704e-3633.57glutamate rich 3 [Source:Xenbase;Acc:XB-GENE-58807... [more]
irf62.950e-3635.65interferon regulatory factor 6 [Source:Xenbase;Acc... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cracr2a9.981e-7629.70calcium release activated channel regulator 2A [So... [more]
Rab135.940e-3942.86RAB13, member RAS oncogene family [Source:MGI Symb... [more]
Rab8b2.948e-3740.57RAB8B, member RAS oncogene family [Source:MGI Symb... [more]
Rab1b8.055e-3735.18RAB1B, member RAS oncogene family [Source:MGI Symb... [more]
Rab1a5.039e-3635.12RAB1A, member RAS oncogene family [Source:MGI Symb... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P35286|RAB13_RAT1.338e-3843.45Ras-related protein Rab-13 OS=Rattus norvegicus OX... [more]
sp|Q9DD03|RAB13_MOUSE4.155e-3842.86Ras-related protein Rab-13 OS=Mus musculus OX=1009... [more]
sp|Q5KTJ6|RAB13_MESAU2.159e-3742.86Ras-related protein Rab-13 OS=Mesocricetus auratus... [more]
sp|Q58DS5|RAB13_BOVIN4.572e-3742.86Ras-related protein Rab-13 OS=Bos taurus OX=9913 G... [more]
sp|P51153|RAB13_HUMAN4.617e-3742.86Ras-related protein Rab-13 OS=Homo sapiens OX=9606... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3NZE81.085e-12438.06Ras and EF-hand domain-containing protein homolog ... [more]
A0A0B7BKP71.153e-11537.17EF-hand domain-containing protein OS=Arion vulgari... [more]
A0A2C9JD037.439e-11237.30EF-hand domain-containing protein OS=Biomphalaria ... [more]
A0A2C9JD091.101e-11137.30EF-hand domain-containing protein OS=Biomphalaria ... [more]
A0A2C9JD111.275e-11137.30EF-hand domain-containing protein OS=Biomphalaria ... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cracr2ab1.045e-4630.88calcium release activated channel regulator 2Ab [S... [more]
megf86.729e-3840.57ras-related protein Rab-8B [Source:NCBI gene;Acc:1... [more]
rab131.620e-3738.74RAB13, member RAS oncogene family [Source:NCBI gen... [more]
ENSAMXT00000056277.11.822e-3738.42ras-related protein Rab-10-like [Source:NCBI gene;... [more]
rab1ba2.516e-3735.64zRAB1B, member RAS oncogene family a [Source:ZFIN;... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rab1aa3.947e-3836.10RAB1A, member RAS oncogene family a [Source:ZFIN;A... [more]
rab8a6.167e-3841.71RAB8A, member RAS oncogene family [Source:ZFIN;Acc... [more]
rasef3.039e-3637.93RAS and EF-hand domain containing [Source:ZFIN;Acc... [more]
ENSPMAT00000002219.18.083e-3338.07pep scaffold:Pmarinus_7.0:GL483980:50:9020:-1 gene... [more]
rab302.134e-3237.72RAB30, member RAS oncogene family [Source:ZFIN;Acc... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
SEC44.432e-3741.21Rab family GTPase; essential for vesicle-mediated ... [more]
YPT532.181e-3538.76Stress-induced Rab family GTPase; required for vac... [more]
VPS213.554e-3439.49Endosomal Rab family GTPase; required for endocyti... [more]
YPT14.998e-3335.93Rab family GTPase; involved in the ER-to-Golgi ste... [more]
YPT315.426e-3238.99Rab family GTPase; involved in the exocytic pathwa... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO283992.139e-4849.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO478222.139e-4849.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO474711.031e-4041.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO479908.052e-3937.14Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO410181.268e-3842.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000027276.19.208e-8231.80calcium release activated channel regulator 2A [So... [more]
ENSORLT00000035474.19.208e-8231.80calcium release activated channel regulator 2A [So... [more]
ENSORLT00000046122.19.208e-8231.80calcium release activated channel regulator 2A [So... [more]
cracr2ab2.268e-4139.49ras and EF-hand domain-containing protein homolog ... [more]
rasef5.154e-3940.10RAS and EF-hand domain containing [Source:NCBI gen... [more]
back to top
BLAST of Ras and EF-hand domain-containing protein homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000049749.10.000e+099.67SMESG000049749.1[more]
SMESG000049774.10.000e+099.05SMESG000049774.1[more]
SMESG000043201.18.687e-5841.77SMESG000043201.1[more]
SMESG000039353.12.286e-5447.18SMESG000039353.1[more]
SMESG000040702.18.875e-4844.10SMESG000040702.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027563 ID=SMED30027563|Name=Ras and EF-hand domain-containing protein homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=2376bp
CAATAAACGATTTGTTGAGTGCTAAAATTGATTATTATGCACAAATTTAC
ACGCAATCGATTTGTGAAATCTACCAATGAAAAATCTAGCAGAGAAATTG
TGAATTTAATCAATAATTTCACTGATTGAGTTGAGCCACGGACTGAACCA
AAAAATCATGTCACAGGCACATCATTCGATATTTGAAGATCAAGCGAGAG
AGCTGTATTTTCTTTGTGATGAGGAGAAAAAAGGATTTATTACCAAGGAA
GACATGTATCGACTTACTGATCATTTGCCGTTGAATAAAGAACAATTCGA
ATCTGTTTTTGATTCTTTGGATGATGATAATAATGGAAATCTGACATTGG
AGGAATTCATTGTTGGTTTCAGTAAATTCTTGGGCGCACCGGTCGAAATT
CCCCATGACGATGATTTGGAATTCGATGATGAGGGATCATCCCTGAATCA
AGTGGCCCAGGAGCATCTGGAGCATCTCATAGAAAAAATGAAAATTGTTG
GATTAACGGAAGACATTGACAATATAAAAGAAACTTGGAATCAGTTGCAA
AACAGCAACGCAGAATTACTGAGCCACTTCGAAACGTTAATCGAAACCAT
CATATCAGATATGCACAAAGCTAAAAATGAATACAACACATTGGAGGGGG
TGCTGAAAAGTAAATCCAACATTTACGACGAGGAAATGAAACGGTTGTAC
GACGAAATGGACCTTCAAATAAAAGCTGAAAAAGAACGCCTCTTGAATGA
AGAAAAGAAACGAGAAAAAGAAATTAAAGATAATTTAGAAATTGAAATAC
GCGAAAAAGATAAACTGTACCAGGAAATCCTTAAAGATCATGACAAGACA
GTCAAAGAACTACAAAATTTGAGTGACATCCATTCGGAATCAAGTCAAGA
GCGTGAAAGACTTGAAAAAGAAAAAAATGAACTAGAAAATAAACTCCGAG
TGACTGACAAATCAGTCCGAGATTGTCAAGAATACATTGATGAACTCAAC
AAAAAATCAAAACAGGATCGGAGAAATCGTGCAAGAGCTGCAATCGAAAT
GACAGAAGGCATTGCTTTAGAGCGAGAGAGTTTAGTTCGCCAACTTGATG
AATTGAGAGAAATAAACAAACAGTTACAAGAAGAAAAGGCTAGAAAATTA
GACAAATCTAATTTTTCTTCTTCAAATGGCTCTATGGATCTTTATAAAGA
ATTATCAATGGCACAGGAACAAAGTCAGCCAAAAGTAATAGATGTGGCAG
ATTTAAAGAAAAAGCGGGGGTCGATTTTAAGCAGTTATTTTGTACCTAAA
ATAAATGTCGATCAAGTATCTCACGAACGTTGCCAAAGCATGTCATATGA
CGATGAAGATGTGTTAACGGATTTAGGAACTTCATACAACGATTTCAGTT
ATGATGCAATAAGAGTAGAAAATAATGTTACCAGTAGTCATAATCCGATC
CATTCAACAAGTGTAGCACTTTCCCCATCTTATCAAGAAATGGAAATTCA
GACTCTAATTGATAATGAAGAAAAACTTGGTGAAAGGTCTCCTCCTGATG
GAGCAGTGGAAGAAGTTGATATTATAAAAGGCCCAGAAAAGCCAGAAAGA
ATATTTAAAGTCGTTTTTATTGGGGACTCGTCTGTTGGTAAAACAAGTAT
CATAAAACGGTTTTGCAACAATGAATTCCGCAGTGAAGGAATCGCCAGTA
CAATTGGTGTTGATTTTCAAATCAAATCCATCAGAATCGGTGAATATTTC
GTAGCACTTCAAATATGGGACACAGCTGGACAGGAACGGTTTCGCAGCAT
AACTTCACATTACTATCGGAAATCTGACGGAGTTGTCATGGTGTATGATA
TTGTTTCGGAGTCGTCTTTGATAAATTTACGGCAATGGATGGAGAATGTG
AAAGAAGCAGTTGAAGATGAGACTGTGATATTAGTTCTGGCCAACAAATG
CGATATGGTTCAAGGGGAGGAAAATAGAAATCAAGCCAGTCGGTTGAAGG
ATCTTCTTAATGTGGAAAATGTTTTATATTTCCACTGCAGCGCTAAAACG
GGAGAAAATATAAATGAGGCATTTCAGCTCATGGCCAAGAATCTCACAAA
CAAGGAAAATAACGACCTGAAAACCGCCATCAAACTAGATACCAAGCCCA
AGAAAGGCTGTTGCGGTCGATAGGAAACTTCCTGTGAAATATATTTGCTA
GATTTATCGGAAACATTTAGTCTCATCTCTTTGATGTATATTGGTTTAGA
ATTTGGTATTTCGTTCGTGTTTCTGGCTCGTTGCCATTATTTAATGATAA
ATATTTATTATTGGTTGAATTTGATTGGTTGTTTTATTCACTTGTTATAA
TTTTGATGTAATTTCATTGGATAAAA
back to top

protein sequence of SMED30027563-orf-1

>SMED30027563-orf-1 ID=SMED30027563-orf-1|Name=SMED30027563-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=672bp
MSQAHHSIFEDQARELYFLCDEEKKGFITKEDMYRLTDHLPLNKEQFESV
FDSLDDDNNGNLTLEEFIVGFSKFLGAPVEIPHDDDLEFDDEGSSLNQVA
QEHLEHLIEKMKIVGLTEDIDNIKETWNQLQNSNAELLSHFETLIETIIS
DMHKAKNEYNTLEGVLKSKSNIYDEEMKRLYDEMDLQIKAEKERLLNEEK
KREKEIKDNLEIEIREKDKLYQEILKDHDKTVKELQNLSDIHSESSQERE
RLEKEKNELENKLRVTDKSVRDCQEYIDELNKKSKQDRRNRARAAIEMTE
GIALERESLVRQLDELREINKQLQEEKARKLDKSNFSSSNGSMDLYKELS
MAQEQSQPKVIDVADLKKKRGSILSSYFVPKINVDQVSHERCQSMSYDDE
DVLTDLGTSYNDFSYDAIRVENNVTSSHNPIHSTSVALSPSYQEMEIQTL
IDNEEKLGERSPPDGAVEEVDIIKGPEKPERIFKVVFIGDSSVGKTSIIK
RFCNNEFRSEGIASTIGVDFQIKSIRIGEYFVALQIWDTAGQERFRSITS
HYYRKSDGVVMVYDIVSESSLINLRQWMENVKEAVEDETVILVLANKCDM
VQGEENRNQASRLKDLLNVENVLYFHCSAKTGENINEAFQLMAKNLTNKE
NNDLKTAIKLDTKPKKGCCGR*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003924GTPase activity
GO:0005509calcium ion binding
GO:0005525GTP binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000429neoblast
PLANA:0000484secretory system
PLANA:0002020chromatoid body
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR005225Small_GTP-bd_dom
IPR002048EF_hand_dom
IPR001806Small_GTPase
IPR027417P-loop_NTPase
IPR011992EF-hand-dom_pair
IPR018247EF_Hand_1_Ca_BS
Vocabulary: biological process
TermDefinition
GO:0007264small GTPase mediated signal transduction
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 306..333
NoneNo IPR availableCOILSCoilCoilcoord: 235..269
NoneNo IPR availableCOILSCoilCoilcoord: 277..297
NoneNo IPR availableCOILSCoilCoilcoord: 200..227
NoneNo IPR availablePRINTSPR00449RASTRNSFRMNGcoord: 587..600
score: 32.26
coord: 483..504
score: 43.8
coord: 525..547
score: 48.53
coord: 624..646
score: 32.6
coord: 507..523
score: 27.47
NoneNo IPR availableSMARTSM00173ras_sub_4coord: 480..649
e-value: 1.3E-11
score: 47.0
NoneNo IPR availableSMARTSM00174rho_sub_3coord: 485..649
e-value: 4.3E-11
score: 22.7
NoneNo IPR availableSMARTSM00176ran_sub_2coord: 488..669
e-value: 0.0029
score: -1.8
NoneNo IPR availableSMARTSM00177arf_sub_2coord: 466..650
e-value: 3.8E-4
score: 12.3
NoneNo IPR availableSMARTSM00175rab_sub_5coord: 483..649
e-value: 3.5E-63
score: 225.9
NoneNo IPR availablePFAMPF13833EF-hand_8coord: 25..71
e-value: 1.1E-8
score: 34.8
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 1..80
e-value: 4.9E-10
score: 41.6
NoneNo IPR availableGENE3DG3DSA:3.40.50.300coord: 473..667
e-value: 4.5E-57
score: 194.6
NoneNo IPR availablePANTHERPTHR22621:SF27EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 4Bcoord: 12..669
NoneNo IPR availablePANTHERPTHR22621UNCHARACTERIZEDcoord: 12..669
NoneNo IPR availablePROSITEPS51419RABcoord: 478..669
score: 29.32
NoneNo IPR availableCDDcd00154Rabcoord: 483..644
e-value: 3.17633E-66
score: 212.701
IPR005225Small GTP-binding protein domainTIGRFAMTIGR00231TIGR00231coord: 481..643
e-value: 1.1E-27
score: 94.8
IPR001806Small GTPasePFAMPF00071Rascoord: 484..646
e-value: 4.3E-47
score: 159.7
IPR018247EF-Hand 1, calcium-binding sitePROSITEPS00018EF_HAND_1coord: 55..67
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 42..77
score: 12.17
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILYSSF52540P-loop containing nucleoside triphosphate hydrolasescoord: 477..650
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 9..75