Cathepsin F
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30027540 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 27Note: Hover over icons to view figure legend
Homology
BLAST of Cathepsin F vs. Ensembl Human
Match: CTSF (cathepsin F [Source:HGNC Symbol;Acc:HGNC:2531]) HSP 1 Score: 295.434 bits (755), Expect = 6.422e-93 Identity = 152/307 (49.51%), Postives = 201/307 (65.47%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAV--------DWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
F +F +N+ Y+++EE R +F +N +A + LD+G+A YGVT+FSDLT+EEFR+ YL+ L K P +K A++V DWR+ G VT VK+QG CGSCWAFS TGNVEGQWFL L+SLSEQ+L+DCD +D C GGLPS AY AI+ +GGLE+ED Y Y + +C K VYIN S + +E +A W + GPIS+ INAF MQFYR GIS P C+P +DH VL+VG+ + S PFW +KNSWG WGE GYY ++RGSG CG+N MA+++V++
Sbjct: 187 FKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTL--LRKEPG------NKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGN-RSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAVVD 484
BLAST of Cathepsin F vs. Ensembl Human
Match: CTSF (cathepsin F [Source:HGNC Symbol;Acc:HGNC:2531]) HSP 1 Score: 226.868 bits (577), Expect = 3.224e-69 Identity = 124/256 (48.44%), Postives = 161/256 (62.89%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAV--------DWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVL 1426
F +F +N+ Y+++E R +F +N +A + LD+G+A YGVT+FSDLT+EEFR+ YL+ L K P +K A++V DWR+ G VT VK+QG CGSCWAFS TGNVEGQWFL L+SLSEQ+L+DCD +D C GGLPS AY AI+ +GGLE+ED Y Y + +C K VYIN S + +E +A W + GPIS+ INAF MQFYR GIS P C+P +DH VL
Sbjct: 36 FKNFVITYNRTYESKEARW-RLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTL--LRKEPG------NKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDHAVL 282
BLAST of Cathepsin F vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537]) HSP 1 Score: 197.208 bits (500), Expect = 1.919e-57 Identity = 124/306 (40.52%), Postives = 166/306 (54.25%), Query Frame = 2
Query: 692 FKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMN---RLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIV--GFNSTTS-GEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
+K N+LY EE +R ++ N K L N R K S + F D+T EEFR Q ++ + R ++ Q P + ++VDWR G VT VKNQG CGSCWAFS TG +EGQ F KT RL+SLSEQ LVDC + GCNGGL A++ +Q GGL+SE+SYPY A + +C + G I E + + GPIS+ I+A + FY+ GI F C+ +DHGVL+V GF ST S +W+VKNSWGE WG GY + + CG+ A+ +
Sbjct: 32 WKAMHNRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFR-QVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIY--FEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
BLAST of Cathepsin F vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537]) HSP 1 Score: 197.208 bits (500), Expect = 1.919e-57 Identity = 124/306 (40.52%), Postives = 166/306 (54.25%), Query Frame = 2
Query: 692 FKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMN---RLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIV--GFNSTTS-GEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
+K N+LY EE +R ++ N K L N R K S + F D+T EEFR Q ++ + R ++ Q P + ++VDWR G VT VKNQG CGSCWAFS TG +EGQ F KT RL+SLSEQ LVDC + GCNGGL A++ +Q GGL+SE+SYPY A + +C + G I E + + GPIS+ I+A + FY+ GI F C+ +DHGVL+V GF ST S +W+VKNSWGE WG GY + + CG+ A+ +
Sbjct: 32 WKAMHNRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFR-QVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIY--FEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
BLAST of Cathepsin F vs. Ensembl Human
Match: CTSW (cathepsin W [Source:HGNC Symbol;Acc:HGNC:2546]) HSP 1 Score: 193.356 bits (490), Expect = 2.064e-55 Identity = 106/323 (32.82%), Postives = 158/323 (48.92%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRS--QYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALG-GVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNAN--KGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGE-------------------PFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
F F+ FN+ Y + EE A R IF N +A + D G+A +GVT FSDLT+EEF Y A + + I + + DWR + ++ +K+Q +C CWA + GN+E W + V +S Q+L+DC +GC+GG A+ + GL SE YP+ C K + +I + ++E +A + + GPI++ IN +Q YR G+ C+P +DH VL+VGF S S E P+WI+KNSWG WGE GY+ ++RGS CG+ K T+ +
Sbjct: 42 FKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQDFIMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITKFPLTARVQ 364
BLAST of Cathepsin F vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597500:1 gene:WBGene00007055.1 transcript:F41E6.6.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196) HSP 1 Score: 341.273 bits (874), Expect = 2.944e-111 Identity = 186/454 (40.97%), Postives = 259/454 (57.05%), Query Frame = 2
Query: 299 KDKDLQEVF-REAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRN-------ELKRSNQLLSECGLNENLAPKRAKLQIVSTPWLEPKHHFEVMSEIEELD-----LKLHDQLFVLGLPDGEVVSGLN------FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRS-----QYLSPAYDLSK---RPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
+D+ L E F R + K+N + N Y + + + +++ GI Y VTLV T+C+ + R L +C + + KR + + E I++ D L D + V L +++ + F F K Y N+ E KRF++F N K + + ++G+AVYG T+FSD+T EF+ Q+ P Y + + ++ +D+ ++ DWR G VT VKNQG+CGSCWAFSTTGNVEG WF+ +LVSLSEQ+LVDCD++D GCNGGLPS AYK I +MGGLE ED+YPY+ C L + IAVYINGS + E M W GPISIG+NA +QFYR G+ HPF IFC P L+HGVLIVG+ +P+WIVKNSWG +WGE GY+ +YRG VCG+ +MAT++++N
Sbjct: 28 EDQLLYEKFARHGVEKFNQQSNDAYKWELDRTWEVERKLSGGIHYSIFVTLVKTDCKKGQTDVEGKKCRKTDTLKKCQVEISRRVKRHGYGLKDIVHIRNCEE-EFTRNIDKFDHRKIQLTHDDSITVQELRKAKIIRPRDYVIWNSFLDFVDRHEKKYTNKREVLKRFRVFKKNAKVIRELQKNEQGTAVYGFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTINEEDL--PESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSMDQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPHDEVEMQKWLVTKGPISIGLNANTLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKDGR-KPYWIVKNSWGPNWGEAGYFKLYRGKNVCGVQEMATSALVN 477
BLAST of Cathepsin F vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597469:1 gene:WBGene00007055.1 transcript:F41E6.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196) HSP 1 Score: 341.273 bits (874), Expect = 2.944e-111 Identity = 186/454 (40.97%), Postives = 259/454 (57.05%), Query Frame = 2
Query: 299 KDKDLQEVF-REAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRN-------ELKRSNQLLSECGLNENLAPKRAKLQIVSTPWLEPKHHFEVMSEIEELD-----LKLHDQLFVLGLPDGEVVSGLN------FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRS-----QYLSPAYDLSK---RPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
+D+ L E F R + K+N + N Y + + + +++ GI Y VTLV T+C+ + R L +C + + KR + + E I++ D L D + V L +++ + F F K Y N+ E KRF++F N K + + ++G+AVYG T+FSD+T EF+ Q+ P Y + + ++ +D+ ++ DWR G VT VKNQG+CGSCWAFSTTGNVEG WF+ +LVSLSEQ+LVDCD++D GCNGGLPS AYK I +MGGLE ED+YPY+ C L + IAVYINGS + E M W GPISIG+NA +QFYR G+ HPF IFC P L+HGVLIVG+ +P+WIVKNSWG +WGE GY+ +YRG VCG+ +MAT++++N
Sbjct: 28 EDQLLYEKFARHGVEKFNQQSNDAYKWELDRTWEVERKLSGGIHYSIFVTLVKTDCKKGQTDVEGKKCRKTDTLKKCQVEISRRVKRHGYGLKDIVHIRNCEE-EFTRNIDKFDHRKIQLTHDDSITVQELRKAKIIRPRDYVIWNSFLDFVDRHEKKYTNKREVLKRFRVFKKNAKVIRELQKNEQGTAVYGFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTINEEDL--PESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSMDQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPHDEVEMQKWLVTKGPISIGLNANTLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKDGR-KPYWIVKNSWGPNWGEAGYFKLYRGKNVCGVQEMATSALVN 477
BLAST of Cathepsin F vs. Ensembl Celegans
Match: R09F10.1 (pep chromosome:WBcel235:X:8323592:8325046:1 gene:WBGene00019986.1 transcript:R09F10.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:R09F10.1) HSP 1 Score: 195.667 bits (496), Expect = 1.035e-56 Identity = 115/306 (37.58%), Postives = 167/306 (54.58%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLS---PAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGN-CALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAF-AMQFYRGGISHPFSIFCNPNHLD-HGVLIVGFNSTTSGE-PFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
F+ F F++ Y + EE R++IF N + + G + V +F+D TDEE + YD S + + ++DWR G +T +KNQG CGSCWAF+T +VE Q +K +LVSLSEQ++VDCD +NGC+GG A K +++ GLESE YPY+A K + C L ++ V+I+ + ++E +ANW GP++ G+N AM YR GI +P C + H + I+G+ GE +WIVKNSWG SWG +GY+ + RG CGL +IN
Sbjct: 82 FNDFILKFDRKYTSVEEFEYRYQIFLRNVIEFEAEEERNLGLDL-DVNEFTDWTDEELQKMVQENKYTKYDFDTPKFEGSYLETGVIRPASIDWREQGKLTPIKNQGQCGSCWAFATVASVEAQNAIKKGKLVSLSEQEMVDCDGRNNGCSGGYRPYAMKFVKE-NGLESEKEYPYSALKHDQCFLKENDTRVFIDDFRMLSNNEEDIANWVGTKGPVTFGMNVVKAMYSYRSGIFNPSVEDCTEKSMGAHALTIIGYGG--EGESAYWIVKNSWGTSWGASGYFRLARGVNSCGLANTVVAPIIN 383
BLAST of Cathepsin F vs. Ensembl Celegans
Match: R07E3.1 (pep chromosome:WBcel235:X:10339226:10341095:-1 gene:WBGene00011102.1 transcript:R07E3.1b.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:R07E3.1) HSP 1 Score: 179.874 bits (455), Expect = 3.713e-51 Identity = 104/303 (34.32%), Postives = 157/303 (51.82%), Query Frame = 2
Query: 689 SFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMN-RLDKGSAVYGVTQFSDLTDEEFRSQYLSPAY--DLSKRPQRISQIPQDIKTAQA---------VDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGN-CALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAF-AMQFYRGGISHPFSIFCNPNHLD-HGVLIVGFNSTTSGEPFWIVKNSWGESWG-ENGYYLVYRGSGVCGL 1549
++ + F+K Y +E KR +++ + N + + GSA YG SD TDEEF L ++ L K + I IP+ + + DWR +T VK QG CGSCWAF++T VE W + +LSEQ L+DCD +DN C+GG +A++ I + GL + PY A++ N CA++ I + + E + NW GP++IG+ M+ Y+GG+ P C + H +LI G+ ++ +GE +WIVKNSWG +WG E+GY RG CG+
Sbjct: 38 AYTEKFDKSYATSQESLKRLNAYYNTDENIANWNIQNEHGSAEYGHNDMSDWTDEEFEKTLLPKSFYKRLHKEAEFIEPIPESLTAKKGESSSPFPDFFDWRDKNVITPVKAQGQCGSCWAFASTATVEAAWAIAHGEKRNLSEQTLLDCDLVDNACDGGDEDKAFRYIHR-NGLANAVDLPYVAHRQNGCAVNDHWNTTRIKAAYFLHHDEDSIINWLVNFGPVNIGMAVIQPMRAYKGGVFTPSEYACKNEVIGLHALLITGYGTSKTGEKYWIVKNSWGNTWGVEHGYIYFARGINACGI 339
BLAST of Cathepsin F vs. Ensembl Celegans
Match: R07E3.1 (pep chromosome:WBcel235:X:10339226:10340968:-1 gene:WBGene00011102.1 transcript:R07E3.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:R07E3.1) HSP 1 Score: 179.874 bits (455), Expect = 3.713e-51 Identity = 104/303 (34.32%), Postives = 157/303 (51.82%), Query Frame = 2
Query: 689 SFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMN-RLDKGSAVYGVTQFSDLTDEEFRSQYLSPAY--DLSKRPQRISQIPQDIKTAQA---------VDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGN-CALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAF-AMQFYRGGISHPFSIFCNPNHLD-HGVLIVGFNSTTSGEPFWIVKNSWGESWG-ENGYYLVYRGSGVCGL 1549
++ + F+K Y +E KR +++ + N + + GSA YG SD TDEEF L ++ L K + I IP+ + + DWR +T VK QG CGSCWAF++T VE W + +LSEQ L+DCD +DN C+GG +A++ I + GL + PY A++ N CA++ I + + E + NW GP++IG+ M+ Y+GG+ P C + H +LI G+ ++ +GE +WIVKNSWG +WG E+GY RG CG+
Sbjct: 38 AYTEKFDKSYATSQESLKRLNAYYNTDENIANWNIQNEHGSAEYGHNDMSDWTDEEFEKTLLPKSFYKRLHKEAEFIEPIPESLTAKKGESSSPFPDFFDWRDKNVITPVKAQGQCGSCWAFASTATVEAAWAIAHGEKRNLSEQTLLDCDLVDNACDGGDEDKAFRYIHR-NGLANAVDLPYVAHRQNGCAVNDHWNTTRIKAAYFLHHDEDSIINWLVNFGPVNIGMAVIQPMRAYKGGVFTPSEYACKNEVIGLHALLITGYGTSKTGEKYWIVKNSWGNTWGVEHGYIYFARGINACGI 339
BLAST of Cathepsin F vs. Ensembl Fly
Match: CG12163 (gene:FBgn0260462 transcript:FBtr0078822) HSP 1 Score: 285.034 bits (728), Expect = 2.002e-89 Identity = 166/427 (38.88%), Postives = 229/427 (53.63%), Query Frame = 2
Query: 374 YAPYQVHSIRQQVVAGILYEFEVTLVGTN-----CRNEL-------KRSNQLLSECGLNENLAPKRAKLQIVSTPWLEPKHHFEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKR--------PQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGE-----PFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVI 1576
Y +V+S +QV +GIL + L+ + C ++ K +++ +C N+ + R S W E K H K H F + V L F F+ F + Y + E R +IF N K +N + GSA YG+T+F+D+T E++ + D +K P ++P++ DWR VT VKNQGSCGSCWAFS TGN+EG + +KT L SEQ+L+DCDT D+ CNGGL AYKAI+ +GGLE E YPY A K C +++ V + G + +E+ M W NGPISIGINA AMQFYRGG+SHP+ C+ +LDHGVL+VG+ + P+WIVKNSWG WGE GYY VYRG CG+++MAT++V+
Sbjct: 78 YKIVKVYSASRQVDSGILTRIDADLIDGSEEQHRCIVDIWTKVWVRKDEHEITFKC-RNQPVVQAR---HTRSVEWAEKKTH------------KKHSHRF-------DKVDHL-FYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAYHGELPKEF------DWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVL 474
BLAST of Cathepsin F vs. Ensembl Fly
Match: CG12163 (gene:FBgn0260462 transcript:FBtr0078823) HSP 1 Score: 285.034 bits (728), Expect = 6.831e-88 Identity = 142/312 (45.51%), Postives = 189/312 (60.58%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKR--------PQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGE-----PFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVI 1576
F F+ F + Y + E R +IF N K +N + GSA YG+T+F+D+T E++ + D +K P ++P++ DWR VT VKNQGSCGSCWAFS TGN+EG + +KT L SEQ+L+DCDT D+ CNGGL AYKAI+ +GGLE E YPY A K C +++ V + G + +E+ M W NGPISIGINA AMQFYRGG+SHP+ C+ +LDHGVL+VG+ + P+WIVKNSWG WGE GYY VYRG CG+++MAT++V+
Sbjct: 308 FYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAYHGELPKEF------DWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVL 613
BLAST of Cathepsin F vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087592) HSP 1 Score: 216.083 bits (549), Expect = 8.435e-65 Identity = 125/313 (39.94%), Postives = 175/313 (55.91%), Query Frame = 2
Query: 689 SFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMN-RLDKGSAVY--GVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQI--------PQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
+FK K YQ+E EE R KIF+ N K N R +G + V +++DL EFR Y L K+ + + P + ++VDWR G VTAVK+QG CGSCWAFS+TG +EGQ F K+ LVSLSEQ LVDC T +NGCNGGL A++ I+ GG+++E SYPY A +C +K + G I E MA + GP+S+ I+A + QFY G+ + C+ +LDHGVL+VGF + SGE +W+VKNSWG +WG+ G+ + R CG+ ++ ++
Sbjct: 31 TFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQ--CDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341
BLAST of Cathepsin F vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087593) HSP 1 Score: 216.853 bits (551), Expect = 1.087e-64 Identity = 125/313 (39.94%), Postives = 175/313 (55.91%), Query Frame = 2
Query: 689 SFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMN-RLDKGSAVY--GVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQI--------PQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
+FK K YQ+E EE R KIF+ N K N R +G + V +++DL EFR Y L K+ + + P + ++VDWR G VTAVK+QG CGSCWAFS+TG +EGQ F K+ LVSLSEQ LVDC T +NGCNGGL A++ I+ GG+++E SYPY A +C +K + G I E MA + GP+S+ I+A + QFY G+ + C+ +LDHGVL+VGF + SGE +W+VKNSWG +WG+ G+ + R CG+ ++ ++
Sbjct: 61 TFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQ--CDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371
BLAST of Cathepsin F vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0339955) HSP 1 Score: 213.386 bits (542), Expect = 9.342e-64 Identity = 123/306 (40.20%), Postives = 172/306 (56.21%), Query Frame = 2
Query: 710 KLYQNEEEEAKRFKIFHSNYKKALLMN-RLDKGSAVY--GVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQI--------PQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGS-GVCGLNKMATTSVI 1576
K YQ+E EE R KIF+ N K N R +G + V +++DL EFR Y L K+ + + P + ++VDWR G VTAVK+QG CGSCWAFS+TG +EGQ F K+ LVSLSEQ LVDC T +NGCNGGL A++ I+ GG+++E SYPY A +C +K + G I E MA + GP+S+ I+A + QFY G+ + C+ +LDHGVL+VGF + SGE +W+VKNSWG +WG+ G+ + R CG+ ++ ++
Sbjct: 35 KNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQ--CDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 338
BLAST of Cathepsin F vs. Ensembl Zebrafish
Match: ctsf (cathepsin F [Source:ZFIN;Acc:ZDB-GENE-030131-9831]) HSP 1 Score: 347.436 bits (890), Expect = 1.705e-113 Identity = 183/439 (41.69%), Postives = 259/439 (59.00%), Query Frame = 2
Query: 302 DKDLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSECGLNENLAPKRAKLQIV-----STPW------LEPKHHFEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLN-FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYD-LSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
D + + + A +YN N+++ ++ S +Q+V G+ Y V + T C K++ +L + + P + K ++ PW L+ K V+ E++ K+ P E V L F +F +N+ Y ++EE KR +IF N K A + L++GSA YG+T+FSDLT++EFR YL+P S + + IP DWR G V+ VKNQG CGSCWAFS TGN+EGQWF KT +L+SLSEQ+LVDCD +D C GGLPS AY+AI+ +GGLE+E Y Y +K +C K+A YIN S + E +A + + NGP+S +NAFAMQFYR G+SHP IFCNP +DH VL+VGF +G PFW +KNSWGE +GE GYY +YRGSG+CG++KM +++++N
Sbjct: 44 DPGVMKAVKFAEERYNMGSNAMHIRRVSKILSASKQLVKGVRYSIMVEIGSTQC----KKAAELSTADTCDFFPEPHKQKTEVCLFEVWDIPWENKSTLLKQKCQPAVVKELK----KVAAVPLTHSKPMKESVELLTMFKNFMITYNRTYSSQEEAEKRLRIFQQNMKTAQTLQSLEQGSAEYGITKFSDLTEDEFRMMYLNPMLSQWSLKKEMKPAIPASAPAPDTWDWRDHGAVSPVKNQGMCGSCWAFSVTGNIEGQWFKKTGQLLSLSEQELVDCDKLDQACGGGLPSNAYEAIENLGGLETETDYSYTGHKQSCDFSTGKVAAYINSSVELPKDEKEIAAFLAENGPVSAALNAFAMQFYRKGVSHPLKIFCNPRMIDHAVLLVGFGQ-RNGVPFWAIKNSWGEDYGEQGYYYLYRGSGLCGIHKMCSSAIVN 473
BLAST of Cathepsin F vs. Ensembl Zebrafish
Match: ctsf (cathepsin F [Source:ZFIN;Acc:ZDB-GENE-030131-9831]) HSP 1 Score: 347.436 bits (890), Expect = 1.705e-113 Identity = 183/439 (41.69%), Postives = 259/439 (59.00%), Query Frame = 2
Query: 302 DKDLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSECGLNENLAPKRAKLQIV-----STPW------LEPKHHFEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLN-FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYD-LSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
D + + + A +YN N+++ ++ S +Q+V G+ Y V + T C K++ +L + + P + K ++ PW L+ K V+ E++ K+ P E V L F +F +N+ Y ++EE KR +IF N K A + L++GSA YG+T+FSDLT++EFR YL+P S + + IP DWR G V+ VKNQG CGSCWAFS TGN+EGQWF KT +L+SLSEQ+LVDCD +D C GGLPS AY+AI+ +GGLE+E Y Y +K +C K+A YIN S + E +A + + NGP+S +NAFAMQFYR G+SHP IFCNP +DH VL+VGF +G PFW +KNSWGE +GE GYY +YRGSG+CG++KM +++++N
Sbjct: 44 DPGVMKAVKFAEERYNMGSNAMHIRRVSKILSASKQLVKGVRYSIMVEIGSTQC----KKAAELSTADTCDFFPEPHKQKTEVCLFEVWDIPWENKSTLLKQKCQPAVVKELK----KVAAVPLTHSKPMKESVELLTMFKNFMITYNRTYSSQEEAEKRLRIFQQNMKTAQTLQSLEQGSAEYGITKFSDLTEDEFRMMYLNPMLSQWSLKKEMKPAIPASAPAPDTWDWRDHGAVSPVKNQGMCGSCWAFSVTGNIEGQWFKKTGQLLSLSEQELVDCDKLDQACGGGLPSNAYEAIENLGGLETETDYSYTGHKQSCDFSTGKVAAYINSSVELPKDEKEIAAFLAENGPVSAALNAFAMQFYRKGVSHPLKIFCNPRMIDHAVLLVGFGQ-RNGVPFWAIKNSWGEDYGEQGYYYLYRGSGLCGIHKMCSSAIVN 473
BLAST of Cathepsin F vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]) HSP 1 Score: 203.371 bits (516), Expect = 7.851e-60 Identity = 124/314 (39.49%), Postives = 179/314 (57.01%), Query Frame = 2
Query: 677 LNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRL-DKGSAVY--GVTQFSDLTDEEFRSQYL-----SPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDS-SESFMANWCSVNGPISIGINA--FAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
+ F ++K F K Y++ EEE+ R + +N K L+ N + D+G Y G+T F+D+++EE+R S ++ ++ + VDWR G VT +K+Q CGSCWAFS TG++EGQ F KT +LVSLSEQQLVDC + GC+GGL QA++ I+ GL++EDSYPY A G C + S + G I S ES + + GPIS+ I+A + Q Y G+ + C+ + LDHGVL VG+ S ++G+ +WIVKNSWG WG GY L+ R S CG+ A+ ++
Sbjct: 24 MEFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPD--CSSSELDHGVLAVGYGS-SNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334
BLAST of Cathepsin F vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]) HSP 1 Score: 203.371 bits (516), Expect = 7.851e-60 Identity = 124/314 (39.49%), Postives = 179/314 (57.01%), Query Frame = 2
Query: 677 LNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRL-DKGSAVY--GVTQFSDLTDEEFRSQYL-----SPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDS-SESFMANWCSVNGPISIGINA--FAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
+ F ++K F K Y++ EEE+ R + +N K L+ N + D+G Y G+T F+D+++EE+R S ++ ++ + VDWR G VT +K+Q CGSCWAFS TG++EGQ F KT +LVSLSEQQLVDC + GC+GGL QA++ I+ GL++EDSYPY A G C + S + G I S ES + + GPIS+ I+A + Q Y G+ + C+ + LDHGVL VG+ S ++G+ +WIVKNSWG WG GY L+ R S CG+ A+ ++
Sbjct: 24 MEFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPD--CSSSELDHGVLAVGYGS-SNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334
BLAST of Cathepsin F vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]) HSP 1 Score: 203.371 bits (516), Expect = 7.851e-60 Identity = 124/314 (39.49%), Postives = 179/314 (57.01%), Query Frame = 2
Query: 677 LNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRL-DKGSAVY--GVTQFSDLTDEEFRSQYL-----SPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDS-SESFMANWCSVNGPISIGINA--FAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
+ F ++K F K Y++ EEE+ R + +N K L+ N + D+G Y G+T F+D+++EE+R S ++ ++ + VDWR G VT +K+Q CGSCWAFS TG++EGQ F KT +LVSLSEQQLVDC + GC+GGL QA++ I+ GL++EDSYPY A G C + S + G I S ES + + GPIS+ I+A + Q Y G+ + C+ + LDHGVL VG+ S ++G+ +WIVKNSWG WG GY L+ R S CG+ A+ ++
Sbjct: 24 MEFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPD--CSSSELDHGVLAVGYGS-SNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334
BLAST of Cathepsin F vs. Ensembl Xenopus
Match: klhl31 (kelch like family member 31 [Source:Xenbase;Acc:XB-GENE-966130]) HSP 1 Score: 377.096 bits (967), Expect = 3.540e-125 Identity = 193/444 (43.47%), Postives = 267/444 (60.14%), Query Frame = 2
Query: 308 DLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSEC--GLNENLAPKRAKLQIVSTPWLEPKHHFEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLN----------------FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRP--QRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
+L++V A+ ++N N Y +V R++VV+G+ Y+ + L T C+ K + LL C ++ L + I+ PW M+E + L ++F++ L D E N F F +NK Y ++EE A+R +IF N KKA ++ +D+G+A YGVT++SDLT++EFRS YL+P LS +P Q I ++ DWR G VT VKNQG CGSCWAFS GN+EGQWFLK LVSLSEQ+LVDCD +D+ C GGLPS AY+AI+++GG+E+E Y Y +K C+ SK++ YIN S I E+ +A W + NGPISI +NAFAMQFYR GISHPF I CNP +DH VL+VG+ +G PFW +KNSWG WGE GYY +YRG+G CG+N M +++V++
Sbjct: 20 ELKQVAEVAVREFNRGNNGEEIYRQIRVTQARKKVVSGLNYDLTLILGRTQCK---KGQDFLLGSCLQTMSPPLMGVKCTFSILIVPW---------MNETKILHQMCSQEIFIVELTDTETSQKQNVPSSELEDEMLKTLTLFKDFVTTYNKKYSDQEEAARRLQIFSQNLKKAQMIQEMDQGTAEYGVTKYSDLTEDEFRSLYLNPL--LSSKPLYQMKKAIVPNMSAPDQWDWRDHGAVTEVKNQGMCGSCWAFSVIGNIEGQWFLKKGSLVSLSEQELVDCDGVDHACAGGLPSNAYEAIEKLGGIETEQEYSYEGHKNTCSFSTSKVSAYINSSVEIPKDENEIAAWLAQNGPISIALNAFAMQFYRKGISHPFRILCNPWMIDHAVLLVGYGE-RNGTPFWAIKNSWGTDWGEQGYYYLYRGTGACGMNTMCSSAVVD 448
BLAST of Cathepsin F vs. Ensembl Xenopus
Match: klhl31 (kelch like family member 31 [Source:Xenbase;Acc:XB-GENE-966130]) HSP 1 Score: 376.711 bits (966), Expect = 8.024e-125 Identity = 193/444 (43.47%), Postives = 267/444 (60.14%), Query Frame = 2
Query: 308 DLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSEC--GLNENLAPKRAKLQIVSTPWLEPKHHFEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLN----------------FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRP--QRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
+L++V A+ ++N N Y +V R++VV+G+ Y+ + L T C+ K + LL C ++ L + I+ PW M+E + L ++F++ L D E N F F +NK Y ++EE A+R +IF N KKA ++ +D+G+A YGVT++SDLT++EFRS YL+P LS +P Q I ++ DWR G VT VKNQG CGSCWAFS GN+EGQWFLK LVSLSEQ+LVDCD +D+ C GGLPS AY+AI+++GG+E+E Y Y +K C+ SK++ YIN S I E+ +A W + NGPISI +NAFAMQFYR GISHPF I CNP +DH VL+VG+ +G PFW +KNSWG WGE GYY +YRG+G CG+N M +++V++
Sbjct: 32 ELKQVAEVAVREFNRGNNGEEIYRQIRVTQARKKVVSGLNYDLTLILGRTQCK---KGQDFLLGSCLQTMSPPLMGVKCTFSILIVPW---------MNETKILHQMCSQEIFIVELTDTETSQKQNVPSSELEDEMLKTLTLFKDFVTTYNKKYSDQEEAARRLQIFSQNLKKAQMIQEMDQGTAEYGVTKYSDLTEDEFRSLYLNPL--LSSKPLYQMKKAIVPNMSAPDQWDWRDHGAVTEVKNQGMCGSCWAFSVIGNIEGQWFLKKGSLVSLSEQELVDCDGVDHACAGGLPSNAYEAIEKLGGIETEQEYSYEGHKNTCSFSTSKVSAYINSSVEIPKDENEIAAWLAQNGPISIALNAFAMQFYRKGISHPFRILCNPWMIDHAVLLVGYGE-RNGTPFWAIKNSWGTDWGEQGYYYLYRGTGACGMNTMCSSAVVD 460
BLAST of Cathepsin F vs. Ensembl Xenopus
Match: klhl31 (kelch like family member 31 [Source:Xenbase;Acc:XB-GENE-966130]) HSP 1 Score: 339.347 bits (869), Expect = 1.064e-112 Identity = 156/285 (54.74%), Postives = 202/285 (70.88%), Query Frame = 2
Query: 731 EEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRP--QRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
E A+R +IF N KKA ++ +D+G+A YGVT++SDLT++EFRS YL+P LS +P Q I ++ DWR G VT VKNQG CGSCWAFS GN+EGQWFLK LVSLSEQ+LVDCD +D+ C GGLPS AY+AI+++GG+E+E Y Y +K C+ SK++ YIN S I E+ +A W + NGPISI +NAFAMQFYR GISHPF I CNP +DH VL+VG+ +G PFW +KNSWG WGE GYY +YRG+G CG+N M +++V++
Sbjct: 14 EAARRLQIFSQNLKKAQMIQEMDQGTAEYGVTKYSDLTEDEFRSLYLNPL--LSSKPLYQMKKAIVPNMSAPDQWDWRDHGAVTEVKNQGMCGSCWAFSVIGNIEGQWFLKKGSLVSLSEQELVDCDGVDHACAGGLPSNAYEAIEKLGGIETEQEYSYEGHKNTCSFSTSKVSAYINSSVEIPKDENEIAAWLAQNGPISIALNAFAMQFYRKGISHPFRILCNPWMIDHAVLLVGYGE-RNGTPFWAIKNSWGTDWGEQGYYYLYRGTGACGMNTMCSSAVVD 295
BLAST of Cathepsin F vs. Ensembl Xenopus
Match: klhl31 (kelch like family member 31 [Source:Xenbase;Acc:XB-GENE-966130]) HSP 1 Score: 333.569 bits (854), Expect = 2.701e-110 Identity = 154/281 (54.80%), Postives = 199/281 (70.82%), Query Frame = 2
Query: 743 RFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRP--QRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
R +IF N KKA ++ +D+G+A YGVT++SDLT++EFRS YL+P LS +P Q I ++ DWR G VT VKNQG CGSCWAFS GN+EGQWFLK LVSLSEQ+LVDCD +D+ C GGLPS AY+AI+++GG+E+E Y Y +K C+ SK++ YIN S I E+ +A W + NGPISI +NAFAMQFYR GISHPF I CNP +DH VL+VG+ +G PFW +KNSWG WGE GYY +YRG+G CG+N M +++V++
Sbjct: 27 RLQIFSQNLKKAQMIQEMDQGTAEYGVTKYSDLTEDEFRSLYLNPL--LSSKPLYQMKKAIVPNMSAPDQWDWRDHGAVTEVKNQGMCGSCWAFSVIGNIEGQWFLKKGSLVSLSEQELVDCDGVDHACAGGLPSNAYEAIEKLGGIETEQEYSYEGHKNTCSFSTSKVSAYINSSVEIPKDENEIAAWLAQNGPISIALNAFAMQFYRKGISHPFRILCNPWMIDHAVLLVGYGE-RNGTPFWAIKNSWGTDWGEQGYYYLYRGTGACGMNTMCSSAVVD 304
BLAST of Cathepsin F vs. Ensembl Xenopus
Match: klhl31 (kelch like family member 31 [Source:Xenbase;Acc:XB-GENE-966130]) HSP 1 Score: 337.035 bits (863), Expect = 1.499e-109 Identity = 180/444 (40.54%), Postives = 253/444 (56.98%), Query Frame = 2
Query: 308 DLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSEC--GLNENLAPKRAKLQIVSTPWLEPKHHFEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLN----------------FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRP--QRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
+L++V A+ ++N N Y +V R++VV+G+ Y+ + L T C+ K + LL C ++ L + I+ PW M+E + L ++F++ L D E N F F +NK Y ++EE A+R +IF N KKA ++ +D+G+A YGVT++SDLT++EFRS YL+P LS +P Q I ++ DWR G VT VKNQG CGSCWAFS GN+EGQWFLK LVSLSEQ+LVDCD +D+ C GGLPS AY+AI+++GG+E+E Y Y +K C+ SK++ YIN S C++ P S+ FYR GISHPF I CNP +DH VL+VG+ +G PFW +KNSWG WGE GYY +YRG+G CG+N M +++V++
Sbjct: 35 ELKQVAEVAVREFNRGNNGEEIYRQIRVTQARKKVVSGLNYDLTLILGRTQCK---KGQDFLLGSCLQTMSPPLMGVKCTFSILIVPW---------MNETKILHQMCSQEIFIVELTDTETSQKQNVPSSELEDEMLKTLTLFKDFVTTYNKKYSDQEEAARRLQIFSQNLKKAQMIQEMDQGTAEYGVTKYSDLTEDEFRSLYLNPL--LSSKPLYQMKKAIVPNMSAPDQWDWRDHGAVTEVKNQGMCGSCWAFSVIGNIEGQWFLKKGSLVSLSEQELVDCDGVDHACAGGLPSNAYEAIEKLGGIETEQEYSYEGHKNTCSFSTSKVSAYINSS-------------CTLITPFSLDFTL----FYRKGISHPFRILCNPWMIDHAVLLVGYGE-RNGTPFWAIKNSWGTDWGEQGYYYLYRGTGACGMNTMCSSAVVD 446
BLAST of Cathepsin F vs. Ensembl Mouse
Match: Ctsf (cathepsin F [Source:MGI Symbol;Acc:MGI:1861434]) HSP 1 Score: 299.671 bits (766), Expect = 4.590e-95 Identity = 150/300 (50.00%), Postives = 196/300 (65.33%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDL-SKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
F F +N+ Y++ EE R +F N +A + LD+G+A YG+T+FSDLT+EEF + YL+P S R ++ D+ + DWR G VT VKNQG CGSCWAFS TGNVEGQWFL L+SLSEQ+L+DCD +D C GGLPS AY AI+ +GGLE+ED Y Y + C VYIN S + +E+ +A W + GPIS+ INAF MQFYR GI+HPF C+P +DH VL+VG+ + S P+W +KNSWG WGE GYY +YRGSG CG+N MA+++V+N
Sbjct: 165 FKDFMTTYNRTYESREEAQWRLTVFARNMIRAQKIQALDRGTAQYGITKFSDLTEEEFHTIYLNPLLQKESGRKMSPAKSINDLAPPE-WDWRKKGAVTEVKNQGMCGSCWAFSVTGNVEGQWFLNRGTLLSLSEQELLDCDKVDKACLGGLPSNAYAAIKNLGGLETEDDYGYQGHVQTCNFSAQMAKVYINDSVELSRNENKIAAWLAQKGPISVAINAFGMQFYRHGIAHPFRPLCSPWFIDHAVLLVGYGN-RSNIPYWAIKNSWGSDWGEEGYYYLYRGSGACGVNTMASSAVVN 462
BLAST of Cathepsin F vs. Ensembl Mouse
Match: Ctsw (cathepsin W [Source:MGI Symbol;Acc:MGI:1338045]) HSP 1 Score: 210.69 bits (535), Expect = 3.226e-62 Identity = 110/325 (33.85%), Postives = 170/325 (52.31%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKT-------AQAVDWR-ALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKG--NCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSG----------------EPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
F F+ FN+ Y N E +R IF N +A + + D G+A +G T FSDLT+EEF Y + P+R + + +++ + DWR A +++VKNQGSC CWA + N++ W +K ++ V +S Q+L+DC+ NGCNGG AY + GL SE YP+ ++ C K K +I + ++E +A++ +V+GPI++ IN +Q Y+ G+ C+P +DH VL+VGF G P+WI+KNSWG WGE GY+ +YRG+ CG+ K T+ ++
Sbjct: 40 FKLFQIRFNRSYWNPAEYTRRLSIFAHNLAQAQRLQQEDLGTAEFGETPFSDLTEEEF-----GQLYGQERSPERTPNMTKKVESNTWGESVPRTCDWRKAKNIISSVKNQGSCKCCWAMAAADNIQALWRIKHQQFVDVSVQELLDCERCGNGCNGGFVWDAYLTVLNNSGLASEKDYPFQGDRKPHRCLAKKYKKVAWIQDFTMLSNNEQAIAHYLAVHGPITVTINMKLLQHYQKGVIKATPSSCDPRQVDHSVLLVGFGKEKEGMQTGTVLSHSRKRRHSSPYWILKNSWGAHWGEKGYFRLYRGNNTCGVTKYPFTAQVD 359
BLAST of Cathepsin F vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564]) HSP 1 Score: 201.83 bits (512), Expect = 3.033e-59 Identity = 123/328 (37.50%), Postives = 176/328 (53.66%), Query Frame = 2
Query: 641 VLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYG-------VTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIVGF---NSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVIN 1579
L P + + +K +LY EEE +R + ++K + M +L G G + F D+T+EEFR Q ++ + R+ Q P +K ++VDWR G VT VKNQG CGSCWAFS +G +EGQ FLKT +L+SLSEQ LVDC + GCNGGL A++ I++ GGL+SE+SYPY A G+C G I E + + GPIS+ ++A ++QFY GI + C+ +LDHGVL+VG+ + ++ +W+VKNSWG WG GY + + CGL A+ V+N
Sbjct: 15 ALATPKFDQTFSAEWHQWKSTHRRLYGTNEEEWRR-----AIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFR-QVVNGYRHQKHKKGRLFQEPLMLKIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIY--YEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVVN 334
BLAST of Cathepsin F vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564]) HSP 1 Score: 201.83 bits (512), Expect = 3.033e-59 Identity = 123/328 (37.50%), Postives = 176/328 (53.66%), Query Frame = 2
Query: 641 VLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYG-------VTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIVGF---NSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVIN 1579
L P + + +K +LY EEE +R + ++K + M +L G G + F D+T+EEFR Q ++ + R+ Q P +K ++VDWR G VT VKNQG CGSCWAFS +G +EGQ FLKT +L+SLSEQ LVDC + GCNGGL A++ I++ GGL+SE+SYPY A G+C G I E + + GPIS+ ++A ++QFY GI + C+ +LDHGVL+VG+ + ++ +W+VKNSWG WG GY + + CGL A+ V+N
Sbjct: 15 ALATPKFDQTFSAEWHQWKSTHRRLYGTNEEEWRR-----AIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFR-QVVNGYRHQKHKKGRLFQEPLMLKIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIY--YEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVVN 334
BLAST of Cathepsin F vs. Ensembl Mouse
Match: Ctsll3 (cathepsin L-like 3 [Source:MGI Symbol;Acc:MGI:1917452]) HSP 1 Score: 192.586 bits (488), Expect = 7.949e-56 Identity = 114/307 (37.13%), Postives = 165/307 (53.75%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYG----VTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDC--DTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINA--FAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
++ +K K Y +E KR N KK + ++ D +G + F DLT+ EFR +K ++ Q P ++VDWR G VT VK+QGSCGSCWAFS G++EGQ F KT +LV LS Q LVDC + GC+GGLP A++ ++ GGL++ SYPY A G C + A + G ++ SSE + + GPIS+GI+ + QFY+ G+ + C+ LDH VL+VG+ + G +W+VKNSWG WG NGY + + + CG+ A+ V+
Sbjct: 29 WEEWKTKHKKTYNMNDEGQKR--AVWENNKKMIDLHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQGQKTKMMMKVFQEPLLGDVPKSVDWRDHGYVTPVKDQGSCGSCWAFSAVGSLEGQMFRKTGKLVPLSVQNLVDCSWSQGNQGCDGGLPDLAFQYVKDNGGLDTSVSYPYEALNGTCRYNPKNSAATVTGFVNVQSSEDALMKAVATVGPISVGIDTKHKSFQFYKEGMY--YEPDCSSTVLDHAVLVVGYGEESDGRKYWLVKNSWGRDWGMNGYIKMAKDRNNNCGIASDASYPVV 331
BLAST of Cathepsin F vs. UniProt/SwissProt
Match: sp|Q26534|CATL_SCHMA (Cathepsin L OS=Schistosoma mansoni OX=6183 GN=CL1 PE=2 SV=1) HSP 1 Score: 322.013 bits (824), Expect = 8.897e-105 Identity = 157/297 (52.86%), Postives = 204/297 (68.69%), Query Frame = 2
Query: 692 FKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDL-SKRPQRISQIPQDIKT-AQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVI 1576
FK + K Y E+E RF IF SN KA L +GSA+YGVT +SDLT +EF +L+ ++ + S R + + +++ + DWR G VT VKNQG CGSCWAFSTTGNVE QWF KT +L+SLSEQQLVDCD +D+GCNGGLPS AY++I +MGGL ED+YPY+A C L +AVYIN S ++ E+ +A W N IS+G+NA +QFY+ GISHP+ IFC+ LDH VL+VG+ + EPFWIVKNSWG WGENGY+ +YRG G CG+N +AT+++I
Sbjct: 23 FKLKYRKQYHETEDEI-RFNIFKSNILKAQLYQVFVRGSAIYGVTPYSDLTTDEFARTHLTASWVVPSSRSNTPTSLGKEVNNIPKNFDWREKGAVTEVKNQGMCGSCWAFSTTGNVESQWFRKTGKLLSLSEQQLVDCDGLDDGCNGGLPSNAYESIIKMGGLMLEDNYPYDAKNEKCHLKTDGVAVYINSSVNLTQDETELAAWLYHNSTISVGMNALLLQFYQHGISHPWWIFCSKYLLDHAVLLVGYGVSEKNEPFWIVKNSWGVEWGENGYFRMYRGDGSCGINTVATSAMI 318
BLAST of Cathepsin F vs. UniProt/SwissProt
Match: sp|Q9R013|CATF_MOUSE (Cathepsin F OS=Mus musculus OX=10090 GN=Ctsf PE=1 SV=1) HSP 1 Score: 299.671 bits (766), Expect = 3.211e-94 Identity = 150/300 (50.00%), Postives = 196/300 (65.33%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDL-SKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
F F +N+ Y++ EE R +F N +A + LD+G+A YG+T+FSDLT+EEF + YL+P S R ++ D+ + DWR G VT VKNQG CGSCWAFS TGNVEGQWFL L+SLSEQ+L+DCD +D C GGLPS AY AI+ +GGLE+ED Y Y + C VYIN S + +E+ +A W + GPIS+ INAF MQFYR GI+HPF C+P +DH VL+VG+ + S P+W +KNSWG WGE GYY +YRGSG CG+N MA+++V+N
Sbjct: 165 FKDFMTTYNRTYESREEAQWRLTVFARNMIRAQKIQALDRGTAQYGITKFSDLTEEEFHTIYLNPLLQKESGRKMSPAKSINDLAPPE-WDWRKKGAVTEVKNQGMCGSCWAFSVTGNVEGQWFLNRGTLLSLSEQELLDCDKVDKACLGGLPSNAYAAIKNLGGLETEDDYGYQGHVQTCNFSAQMAKVYINDSVELSRNENKIAAWLAQKGPISVAINAFGMQFYRHGIAHPFRPLCSPWFIDHAVLLVGYGN-RSNIPYWAIKNSWGSDWGEEGYYYLYRGSGACGVNTMASSAVVN 462
BLAST of Cathepsin F vs. UniProt/SwissProt
Match: sp|Q9UBX1|CATF_HUMAN (Cathepsin F OS=Homo sapiens OX=9606 GN=CTSF PE=1 SV=1) HSP 1 Score: 295.434 bits (755), Expect = 3.084e-92 Identity = 152/307 (49.51%), Postives = 201/307 (65.47%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAV--------DWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
F +F +N+ Y+++EE R +F +N +A + LD+G+A YGVT+FSDLT+EEFR+ YL+ L K P +K A++V DWR+ G VT VK+QG CGSCWAFS TGNVEGQWFL L+SLSEQ+L+DCD +D C GGLPS AY AI+ +GGLE+ED Y Y + +C K VYIN S + +E +A W + GPIS+ INAF MQFYR GIS P C+P +DH VL+VG+ + S PFW +KNSWG WGE GYY ++RGSG CG+N MA+++V++
Sbjct: 187 FKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTL--LRKEPG------NKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGN-RSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGVNTMASSAVVD 484
BLAST of Cathepsin F vs. UniProt/SwissProt
Match: sp|Q9VN93|CPR1_DROME (Putative cysteine proteinase CG12163 OS=Drosophila melanogaster OX=7227 GN=CG12163 PE=2 SV=2) HSP 1 Score: 285.034 bits (728), Expect = 6.847e-87 Identity = 142/312 (45.51%), Postives = 189/312 (60.58%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKR--------PQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGE-----PFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVI 1576
F F+ F + Y + E R +IF N K +N + GSA YG+T+F+D+T E++ + D +K P ++P++ DWR VT VKNQGSCGSCWAFS TGN+EG + +KT L SEQ+L+DCDT D+ CNGGL AYKAI+ +GGLE E YPY A K C +++ V + G + +E+ M W NGPISIGINA AMQFYRGG+SHP+ C+ +LDHGVL+VG+ + P+WIVKNSWG WGE GYY VYRG CG+++MAT++V+
Sbjct: 308 FYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGITEFADMTSSEYKERTGLWQRDEAKATGGSAAVVPAYHGELPKEF------DWRQKDAVTQVKNQGSCGSCWAFSVTGNIEGLYAVKTGELKEFSEQELLDCDTTDSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKNQCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINANAMQFYRGGVSHPWKALCSKKNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRGDNTCGVSEMATSAVL 613
BLAST of Cathepsin F vs. UniProt/SwissProt
Match: sp|Q8VYS0|RD19D_ARATH (Probable cysteine protease RD19D OS=Arabidopsis thaliana OX=3702 GN=RD19D PE=2 SV=1) HSP 1 Score: 263.077 bits (671), Expect = 2.743e-81 Identity = 142/319 (44.51%), Postives = 187/319 (58.62%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKR--------PQ-RISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCD---------TIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNST------TSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATT 1567
F F ++ K Y EE R IF N KA +D SAV+GVTQFSDLT+EEF+ Y A R P + +P+D DWR GGVT VKNQG+CGSCWAFSTTG EG F+ T +L+SLSEQQLVDCD DNGC GGL + AY+ + + GGLE E SYPY +G+C D K+AV + +I E+ +A +GP+++G+NA MQ Y GG+S P + C+ +++HGVL+VG+ S S +P+WI+KNSWG+ WGENGYY + RG +CG+N M +
Sbjct: 51 FRLFMSDYGKNYSTREEYIHRLGIFAKNVLKAAEHQMMDP-SAVHGVTQFSDLTEEEFKRMYTGVADVGGSRGGTVGAEAPMVEVDGLPEDF------DWREKGGVTEVKNQGACGSCWAFSTTGAAEGAHFVSTGKLLSLSEQQLVDCDQACDPKDKKACDNGCGGGLMTNAYEYLMEAGGLEEERSYPYTGKRGHCKFDPEKVAVRVLNFTTIPLDENQIAANLVRHGPLAVGLNAVFMQTYIGGVSCP--LICSKRNVNHGVLLVGYGSKGFSILRLSNKPYWIIKNSWGKKWGENGYYKLCRGHDICGINSMVSA 360
BLAST of Cathepsin F vs. TrEMBL
Match: A0A267DEW1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003424g1 PE=3 SV=1) HSP 1 Score: 431.409 bits (1108), Expect = 7.241e-143 Identity = 215/449 (47.88%), Postives = 273/449 (60.80%), Query Frame = 2
Query: 260 TGEKREISLSKLRKDKDLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSECGLNENLAPK----RAKLQIVSTPWLEPKHH------FEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVI 1576
TG K I+ ++ + + Q E YN+ NS++ +A + ++QVVAGI Y F V T CR ++ L C E L+P R + +V PW P+ + E + L +LG ++ F FK+ K+Y + EE +RF IF N KKA LD+G A YG + F+DLT EEFRS+YLSP +DLS+RP + +P + DWR G VT VKNQG+CGSCWAFSTTGN+EGQWF+ K+LV LSEQQLVDCD +D GCNGGLPSQAYK I++MGGL E YPY + C ++ K+AVYIN S +I E MA W NGPISIGINA AMQFY GISHP+ IFCNP+HLDHGVLIVG+ + EP+WI+KNSWG SWG GYYLVYRG G CGLN+M T++ +
Sbjct: 26 TGGKSPIT-AQDAEGESFQNAITEVTRAYNTYSNSMFHHAMLRYEDAKKQVVAGIRYSFVAVFVETPCRKAVRHYGSPLRWC--KEKLSPDAKVYRCPVSVVYRPWSSPRQYEVDRSGLESCQQTRRLKRSEPQHQVLLGGDSHDIGHYGQFAEFKRAHGKVYASRAEEQRRFAIFRDNMKKAYAYQMLDRGDARYGASVFADLTQEEFRSRYLSPRWDLSRRPAEEAAVPTLGDLPTSFDWREKGAVTEVKNQGTCGSCWAFSTTGNIEGQWFISKKKLVDLSEQQLVDCDKVDEGCNGGLPSQAYKEIERMGGLMKESDYPYRGSDQKCQFNQGKVAVYINSSVAISKDEKAMAAWLVQNGPISIGINANAMQFYLSGISHPWKIFCNPSHLDHGVLIVGYGMKGT-EPYWIIKNSWGTSWGNKGYYLVYRGDGTCGLNQMCTSAQV 470
BLAST of Cathepsin F vs. TrEMBL
Match: A0A267FPA5 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003424g2 PE=3 SV=1) HSP 1 Score: 431.024 bits (1107), Expect = 9.496e-143 Identity = 215/449 (47.88%), Postives = 273/449 (60.80%), Query Frame = 2
Query: 260 TGEKREISLSKLRKDKDLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSECGLNENLAPK----RAKLQIVSTPWLEPKHH------FEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVI 1576
TG K I+ ++ + + Q E YN+ NS++ +A + ++QVVAGI Y F V T CR ++ L C E L+P R + +V PW P+ + E + L +LG ++ F FK+ K+Y + EE +RF IF N KKA LD+G A YG + F+DLT EEFRS+YLSP +DLS+RP + +P + DWR G VT VKNQG+CGSCWAFSTTGN+EGQWF+ K+LV LSEQQLVDCD +D GCNGGLPSQAYK I++MGGL E YPY + C ++ K+AVYIN S +I E MA W NGPISIGINA AMQFY GISHP+ IFCNP+HLDHGVLIVG+ + EP+WI+KNSWG SWG GYYLVYRG G CGLN+M T++ +
Sbjct: 26 TGGKSPIT-AQDAEGESFQNAITEVTRAYNTYSNSMFHHAMLRYEDAKKQVVAGIRYTFVAVFVETPCRKAVRHYGSPLRWC--KEKLSPDAKVYRCPVSVVYRPWSSPRQYEVDRSGLESCQQTRRLKRSEPQHQVLLGGDSHDIGHYGQFAEFKRAHGKVYASRAEEQRRFAIFRDNMKKAYAYQMLDRGDARYGASVFADLTQEEFRSRYLSPRWDLSRRPAEEAAVPTLGDLPTSFDWREKGAVTEVKNQGTCGSCWAFSTTGNIEGQWFISKKKLVDLSEQQLVDCDKVDEGCNGGLPSQAYKEIERMGGLMKESDYPYRGSDQKCQFNQGKVAVYINSSVAISKDEKAMAAWLVQNGPISIGINANAMQFYLSGISHPWKIFCNPSHLDHGVLIVGYGMKGT-EPYWIIKNSWGTSWGNKGYYLVYRGDGTCGLNQMCTSAQV 470
BLAST of Cathepsin F vs. TrEMBL
Match: A0A267FSZ7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021148g1 PE=3 SV=1) HSP 1 Score: 429.098 bits (1102), Expect = 6.475e-142 Identity = 214/433 (49.42%), Postives = 268/433 (61.89%), Query Frame = 2
Query: 311 LQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSECGLNENLAPK----RAKLQIVSTPWLEPKHHFEVMSEIEELD----LKLHDQL---FVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVI 1576
Q E YN+ NS++ +A + ++QVVAGI Y F V T CR ++ L C E L+P R + +V PW P+ + S +E LK + L +LG ++ F FK+ K+Y + EE +RF IF N KKA LD+G A YG + F+DLT EEFRS+YLSP +DLS+RP + +P + DWR G VT VKNQG+CGSCWAFSTTGN+EGQWF+ K+LV LSEQQLVDCD +D GCNGGLPSQAYK I++MGGL E YPY + C ++ K+AVYIN S +I E MA W NGPISIGINA AMQFY GISHP+ IFCNP+HLDHGVLIVG+ + EP+WI+KNSWG SWG GYYLVYRG G CGLN+M T++ +
Sbjct: 42 FQNAITEVTRAYNTYSNSMFHHAMLRYEDAKKQVVAGIRYTFVAVFVETPCRKAVRHYGSPLRWC--KEKLSPDAKVYRCPVSVVYRPWSSPRQYEVDRSGLESCQQTRRLKRSEPLQHQVLLGGDSHDIGHYGQFAEFKRAHGKVYASRAEEQRRFAIFRDNMKKAYAYQMLDRGDARYGASVFADLTQEEFRSRYLSPRWDLSRRPAEEAAVPTLGDLPTSFDWREKGAVTEVKNQGTCGSCWAFSTTGNIEGQWFINKKKLVDLSEQQLVDCDKVDEGCNGGLPSQAYKEIERMGGLMKESDYPYRGSDQKCQFNQGKVAVYINSSVAISKDEKAMAAWLVQNGPISIGINANAMQFYLSGISHPWKIFCNPSHLDHGVLIVGYGMKGT-EPYWIIKNSWGTSWGNKGYYLVYRGDGTCGLNQMCTSAQV 471
BLAST of Cathepsin F vs. TrEMBL
Match: A0A1I8IVL0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 434.491 bits (1116), Expect = 6.414e-136 Identity = 211/433 (48.73%), Postives = 264/433 (60.97%), Query Frame = 2
Query: 311 LQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSECGLNENLAPK----RAKLQIVSTPWLEPKHH------FEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
Q E YN+ NS++ +A + ++QVVAGI Y F V T CR ++ L C E L+P R + +V PW P+ + E + L +LG ++ F FK+ K+Y + EE +RF IF N KKA LD+G A YG + F+DLT EEFRS+YLSP +DLS+RP + +P + DWR G VT VKNQG+CGSCWAFSTTGN+EGQWF+ K+LV LSEQQLVDCD +D GCNGGLPSQAYK I++MGGL E YPY + C ++ K+AVYIN S +I E MA W NGPISIGINA AMQFY GISHP+ IFCNP+HLDHGVLIVG+ + EP+WI+KNSWG SWG GYYLVYRG G CGLN+M T++ +
Sbjct: 737 FQNAITEVTRAYNTYSNSMFHHAMLRYEDAKKQVVAGIRYSFVAVFVETPCRKAVRHYGSPLRWC--KEKLSPDAKVYRCPVSVVYRPWSSPRQYEVDRSGLESCQQTRRLKRSEPQHQVLLGGDSHDIGHYGQFAEFKRAHGKVYASRAEEQRRFAIFRDNMKKAYAYQMLDRGDARYGASVFADLTQEEFRSRYLSPRWDLSRRPAEEAAVPTLGDLPTSFDWREKGAVTEVKNQGTCGSCWAFSTTGNIEGQWFISKKKLVDLSEQQLVDCDKVDEGCNGGLPSQAYKEIERMGGLMKESDYPYRGSDQKCQFNQGKVAVYINSSVAISKDEKAMAAWLVQNGPISIGINANAMQFYLSGISHPWKIFCNPSHLDHGVLIVGYGMKGT-EPYWIIKNSWGTSWGNKGYYLVYRGDGTCGLNQMCTSAQVK 1166
BLAST of Cathepsin F vs. TrEMBL
Match: A0A1I8I5R8 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1) HSP 1 Score: 429.869 bits (1104), Expect = 2.238e-134 Identity = 214/431 (49.65%), Postives = 267/431 (61.95%), Query Frame = 2
Query: 311 LQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSECGLNENLAPK----RAKLQIVSTPWLEPKHHFEVMSEIEELD----LKLHDQL---FVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTS 1570
Q E YN+ NS++ +A + ++QVVAGI Y F V T CR ++ L C E L+P R + +V PW P+ + S +E LK + L +LG ++ F FK+ K+Y + EE +RF IF N KKA LD+G A YG + F+DLT EEFRS+YLSP +DLS+RP + +P + DWR G VT VKNQG+CGSCWAFSTTGN+EGQWF+ K+LV LSEQQLVDCD +D GCNGGLPSQAYK I++MGGL E YPY + C ++ K+AVYIN S +I E MA W NGPISIGINA AMQFY GISHP+ IFCNP+HLDHGVLIVG+ + EP+WI+KNSWG SWG GYYLVYRG G CGLN+M T++
Sbjct: 538 FQNAITEVTRAYNTYSNSMFHHAMLRYEDAKKQVVAGIRYTFVAVFVETPCRKAVRHYGSPLRWC--KEKLSPDAKVYRCPVSVVYRPWSSPRQYEVDRSGLESCQQTRRLKRSEPLQHQVLLGGDSHDIGHYGQFAEFKRAHGKVYASRAEEQRRFAIFRDNMKKAYAYQMLDRGDARYGASVFADLTQEEFRSRYLSPRWDLSRRPAEEAAVPTLGDLPTSFDWREKGAVTEVKNQGTCGSCWAFSTTGNIEGQWFINKKKLVDLSEQQLVDCDKVDEGCNGGLPSQAYKEIERMGGLMKESDYPYRGSDQKCQFNQGKVAVYINSSVAISKDEKAMAAWLVQNGPISIGINANAMQFYLSGISHPWKIFCNPSHLDHGVLIVGYGMKGT-EPYWIIKNSWGTSWGNKGYYLVYRGDGTCGLNQMCTSA 965
BLAST of Cathepsin F vs. Ensembl Cavefish
Match: ctsf (cathepsin F [Source:NCBI gene;Acc:103042155]) HSP 1 Score: 345.51 bits (885), Expect = 9.037e-113 Identity = 188/439 (42.82%), Postives = 264/439 (60.14%), Query Frame = 2
Query: 302 DKDLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQL-LSE-CGLNENLAPKRAKL---QIVSTPW------LEPKHHFEVMSEIEELDLKL-HDQLFVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAY-DLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
D +L + R A +YN N ++ ++ S +Q+V GI Y V + T C K+++ L +SE C ++ ++ ++ PW L+ K V E + + + L D+ L E+++ F F +N+ Y ++EE KR +IF N K A + LD+G+A YGVT+FSDLT++EFR YL+P S + + P A++ DWR G V+ VKNQG CGSCWAFS TGN+EGQWF KT +L+SLSEQ+LVDCD +D C GGLPS AY+AI+ +GGLE+E Y Y +K +C K+A YIN S + E+ +A W NGP+S +NAFAMQFYR G+SHP IFCNP +DH VL+VGF +G PFW +KNSWGE +GE GYY +Y+GS +CG+NKM +++V+N
Sbjct: 42 DPELLKAVRFAEERYNVASNGLHIRRVSRIISASKQLVKGIRYSITVEIGRTQC----KKTDVLHVSEDCEFFPESHKQKTEVCLFEVWDIPWQNKSTLLKQKCQPAVPKETKIVRVPLTRDKTTKESL---ELLT--KFKDFMTTYNRSYISQEEAQKRLRIFQQNLKTAETLQSLDQGTAEYGVTKFSDLTEDEFRMMYLNPMLSQWSLQKKLKPAAPASKAAAESWDWREHGAVSPVKNQGMCGSCWAFSVTGNIEGQWFKKTGQLLSLSEQELVDCDKLDQACGGGLPSNAYEAIENLGGLETETDYTYTGHKQSCGFTSGKVAAYINSSVELSKDENDIAAWLVENGPVSAALNAFAMQFYRKGVSHPLKIFCNPWMIDHAVLLVGFGE-RNGIPFWAIKNSWGEDYGEQGYYYLYKGSRLCGINKMCSSAVVN 470
BLAST of Cathepsin F vs. Ensembl Cavefish
Match: ctsf (cathepsin F [Source:NCBI gene;Acc:103042155]) HSP 1 Score: 343.199 bits (879), Expect = 4.317e-112 Identity = 183/433 (42.26%), Postives = 256/433 (59.12%), Query Frame = 2
Query: 302 DKDLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQL-LSE-CGLNENLAPKRAKL---QIVSTPWLEPKHHFEVMSEIEEL-DLKLHDQLFVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAY-DLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
D +L + R A +YN N ++ ++ S +Q+V GI Y V + T C K+++ L +SE C ++ ++ ++ PW + + L + + L +L F F +N+ Y ++EE KR +IF N K A + LD+G+A YGVT+FSDLT++EFR YL+P S + + P A++ DWR G V+ VKNQG CGSCWAFS TGN+EGQWF KT +L+SLSEQ+LVDCD +D C GGLPS AY+AI+ +GGLE+E Y Y +K +C K+A YIN S + E+ +A W NGP+S +NAFAMQFYR G+SHP IFCNP +DH VL+VGF +G PFW +KNSWGE +GE GYY +Y+GS +CG+NKM +++V+N
Sbjct: 42 DPELLKAVRFAEERYNVASNGLHIRRVSRIISASKQLVKGIRYSITVEIGRTQC----KKTDVLHVSEDCEFFPESHKQKTEVCLFEVWDIPWQNKSTLLKQKCQPAGLCSFRTTESLELL----------TKFKDFMTTYNRSYISQEEAQKRLRIFQQNLKTAETLQSLDQGTAEYGVTKFSDLTEDEFRMMYLNPMLSQWSLQKKLKPAAPASKAAAESWDWREHGAVSPVKNQGMCGSCWAFSVTGNIEGQWFKKTGQLLSLSEQELVDCDKLDQACGGGLPSNAYEAIENLGGLETETDYTYTGHKQSCGFTSGKVAAYINSSVELSKDENDIAAWLVENGPVSAALNAFAMQFYRKGVSHPLKIFCNPWMIDHAVLLVGFGE-RNGIPFWAIKNSWGEDYGEQGYYYLYKGSRLCGINKMCSSAVVN 459
BLAST of Cathepsin F vs. Ensembl Cavefish
Match: ENSAMXT00000001970.2 (cathepsin L1-like [Source:NCBI gene;Acc:103022163]) HSP 1 Score: 207.608 bits (527), Expect = 1.273e-61 Identity = 123/313 (39.30%), Postives = 182/313 (58.15%), Query Frame = 2
Query: 677 LNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRL-DKGSAVY--GVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQI----PQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCD-TIDN-GCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINA--FAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGS-GVCGLNKMATTSVI 1576
L F+S+K K Y +EEEE++R I+ +N K L N L D+G Y G+ F+D+ ++EF++ + + + +D Q VDWRA G VT VKNQG CGSCWAFS TG +EGQ F KT +L+SLSEQQLVDC + N GCNGG PS+++ I+ GLE++ +YPY A K C + ++ +G S+ E+ + N + GPIS+ I+ Q Y+ G+ C+ L+H VL+VG+++ +G+P+W+VKNSWG +WG+NGY + R CG+ +AT ++
Sbjct: 24 LEFNSWKLQHGKSYGSEEEESQRKMIWLTNRKLVLKHNMLADQGLKSYRLGMNIFADMKNQEFQAMFSHCVKSFDETDSLCTSTFLSEDEDAPLPQRVDWRAKGYVTFVKNQGICGSCWAFSATGALEGQMFRKTGKLISLSEQQLVDCSQSFGNLGCNGGWPSKSFDYIKSSKGLEADFTYPYKARKEICRFNPQRVIATCSGFKSLPKGDENALKNAVASIGPISVLIDTSKHTFQLYKSGVYDEPG--CSSTKLNHAVLLVGYDNDPTGKPYWLVKNSWGINWGDNGYIKMSRNKMNQCGIATIATYPLV 334
BLAST of Cathepsin F vs. Ensembl Cavefish
Match: ctsl.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023607]) HSP 1 Score: 202.986 bits (515), Expect = 7.729e-60 Identity = 123/313 (39.30%), Postives = 180/313 (57.51%), Query Frame = 2
Query: 677 LNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRL-DKGSAVY--GVTQFSDLTDEEFRSQYLS--PAYDLSKRPQRISQIPQDIKTA--QAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDC--DTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDS-SESFMANWCSVNGPISIGINA--FAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
L F ++K F K+Y + EEE++R + +N K L+ N L D+G Y G+T F+D+ ++E+R + S +++ +K + + Q ++ VDWR G VT +K+Q CGSCWAFS TG++EGQ F KT +LVSLSEQQLVDC D + GC GGL QA++ I+ G+++EDSYPY A G+C + G I S E + + GPIS+ I+A + Q Y GI + C+ LDHGVL VG+ T +G+ +W+VKNSWG WG GY + R CG+ M++ ++
Sbjct: 24 LEFHAWKLKFGKIYHSVEEESQRKLTWLTNRKLVLVHNMLADQGIKSYRLGMTFFADMDNKEYRKLFASCLGSFNRTKAHSATTFLRQTLRDPLPDTVDWRPKGYVTDIKDQKDCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNFGCGGGLMDQAFEYIKANKGIDTEDSYPYEAVDGDCRFKPDSVGATCTGFVDITSGDEKALQEAVATIGPISVAIDAGHSSFQLYESGIYNEPD--CSSTELDHGVLAVGYG-TDNGKDYWLVKNSWGLDWGNKGYIQMSRNEDNQCGIATMSSYPLV 333
BLAST of Cathepsin F vs. Ensembl Cavefish
Match: ENSAMXT00000001927.2 (cathepsin L1-like [Source:NCBI gene;Acc:107197646]) HSP 1 Score: 199.904 bits (507), Expect = 1.129e-58 Identity = 117/313 (37.38%), Postives = 174/313 (55.59%), Query Frame = 2
Query: 677 LNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRL-DKGSAVY--GVTQFSDLTDEEFRSQ---YLSPAYDLSKRPQ-RISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTID--NGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAFAMQF--YRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
L F +K + K Y +EEEE++R I+ +N K L N L D+G Y G+ F+D+ D+E++ YL P+ R R Q +++ ++DWR G V+ VK QG C SCWAFS G +EGQ F KT LVSLS QQLVDC +D +GC GG A++ I + GGLE+E YPY A +G C + ++ + + E + GP+S+ I++ F Y+ GI + +C+ +++HGVL+VG+N+ +SG +W+VKNSWG WGE GY + R CG+ A+ ++
Sbjct: 24 LEFQEWKLKYGKSYDSEEEESQRKMIWMTNLKLVLEHNMLADQGLKTYRLGMNHFADMDDQEYQQMFRGYLRPSNRTKPRSAGRFLQQAENVALPYSIDWRDNGYVSNVKTQGHCASCWAFSAAGALEGQMFRKTGSLVSLSMQQLVDCSWLDGNDGCGGGSMELAFEYISRSGGLETESDYPYKAREGMCMFNPQDVSGKCHDFEELPKGEEKDLQKAVVAVGPVSVAIDSSNKTFLLYQSGIYN--EPYCSSYNVNHGVLVVGYNTDSSGREYWVVKNSWGVQWGEQGYIRMSRNKDNQCGIATRASFPLV 334
BLAST of Cathepsin F vs. Ensembl Sea Lamprey
Match: ctsf (cathepsin F [Source:ZFIN;Acc:ZDB-GENE-030131-9831]) HSP 1 Score: 313.153 bits (801), Expect = 1.876e-103 Identity = 150/292 (51.37%), Postives = 195/292 (66.78%), Query Frame = 2
Query: 716 YQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQ----RISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
+ ++ E R+++F N+ + + ++GSAVYG+T+FSDLT+EEFR+ +L+P RP+ R +QIP A DWR G VT VKNQG CGSCWAFS TGN+EGQW +K L+SLSEQ+LVDCD +D GC GGL AYK IQ++GGL +E Y Y + C ++K+ YINGS SI S E MA W +GPISI +NA MQFY+ GI+HP+ I C L+H VLIVG+ T G PFWI+KNSWG WGE GYY V+RG GVCGLNK +++V++
Sbjct: 1 FSSKTAEKMRYEVFRENWHRVQKLQETEQGSAVYGITKFSDLTEEEFRALHLNPVLS---RPREVGLRQAQIPPG-PIPPAFDWRDRGAVTEVKNQGECGSCWAFSVTGNIEGQWAIKKGSLLSLSEQELVDCDKLDYGCGGGLQMNAYKTIQELGGLMTESDYSYKGDMEQCGFSQAKVRAYINGSVSISSDEDEMAAWLVKHGPISIALNALGMQFYKHGIAHPWKILCWSWELNHAVLIVGYG-TEKGVPFWIIKNSWGVGWGEEGYYRVFRGDGVCGLNKDCSSAVVD 287
BLAST of Cathepsin F vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011285.1 (pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gene:ENSPMAG00000010258.1 transcript:ENSPMAT00000011285.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 199.904 bits (507), Expect = 9.368e-60 Identity = 126/301 (41.86%), Postives = 169/301 (56.15%), Query Frame = 2
Query: 710 KLYQNEEEEAKRFKIFHSNYKKALLMN---RLDKGSAVYGVTQFSDLTDEEFRSQYLS--PAYDLSKRPQRIS-QIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTID--NGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDS-SESFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
K Y EE +R I+ N KK + N + K + G+ +F D+T EEF+ L + D SK + + P K ++VDWR G VT VK+QG CGSCWAFSTTG++EGQ KT LVSLSEQ LVDC + + NGC GGL A+ I++ GG++SE SYPY A NC + A G I S +E + N + GP+SIGI+A + Q Y GI +S N+LDHGVL+VG+ FWIVKNSWG WG++GY L+ R +CG+ A+ ++
Sbjct: 1 KTYDQNEEGWRRM-IWEKNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTKEEFQHTMLGLRGSNDTSKASRGATFMAPAFFKAPESVDWRKQGYVTDVKDQGDCGSCWAFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSAEGNNGCKGGLMDLAFTYIKKNGGIDSEASYPYTAKDENCKYNPKNKAAEDTGFVDIPSGNEEALKNAVASVGPVSIGIDASLESFQLYSSGI---YSDSDCSNNLDHGVLVVGYGVDDDERKFWIVKNSWGTKWGDHGYILMARDKDNLCGIATAASYPLV 297
BLAST of Cathepsin F vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010475.1 (pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 gene:ENSPMAG00000009483.1 transcript:ENSPMAT00000010475.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 196.823 bits (499), Expect = 9.748e-59 Identity = 116/294 (39.46%), Postives = 166/294 (56.46%), Query Frame = 2
Query: 725 EEEEAKRFKIFHSNYKKALLMN---RLDKGSAVYGVTQFSDLTDEEFRSQYLS--PAYDLSKRPQRIS-QIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTID--NGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYR-GSGVCGLNKMATTSVI 1576
+EEE R I+ N K+ + N + K + G+ QFSD+T EEF+ L SK P+ + P + ++VDWR G VT +KNQG CGSCW+FSTTG++EGQ KT LVSLSEQ LVDC + + +GCNGGL A+ I++ GG++SE+SYPY C D A + G I + E + N + GP+S+ I+A F G C+ +H+DH VL+VG+ G+ FW+VKNSWG +WGE GY + R + +CG+ M++ ++
Sbjct: 1 QEEEGWRRIIWEKNLKRISVHNLEHSMGKHTWRMGMNQFSDMTGEEFQQVMLGFRGWNGTSKAPRGATFMAPAFFEAPESVDWRKQGYVTDIKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNHGCNGGLMINAFNYIKKNGGIDSEESYPYKGQVETCKYDPKNKAAEVTGYVEIPEGDEEALMNAVASVGPVSVAIDASLASFQSYGSGIYKDAMCS-HHIDHAVLVVGYGVDEMGQKFWLVKNSWGVTWGEQGYVRMARDDNNLCGIATMSSYPLV 293
BLAST of Cathepsin F vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006499.1 (pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 gene:ENSPMAG00000005817.1 transcript:ENSPMAT00000006499.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 191.815 bits (486), Expect = 3.538e-56 Identity = 120/316 (37.97%), Postives = 176/316 (55.70%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMN---RLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQ-----IPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTID--NGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGN-CALDKSKIAVYINGSASIDS-SESFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGE---PFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
+ S+K KLY+ ++E +R I+ N K + N L K + G+ F D+T+EEFR Q ++ + + +P ++S+ +PQ+ + VDWR G VT VK+QG CGSCWAFSTTG +EGQ K +LVSLSEQ LVDC + GC GGL QA++ ++ GG++SE +YPY G+ C D + G + S E + + GP+S+ I+A + QFY+ G+ F C+ LDHGVL+VG+ +GE +WIVKNSW WG+ GY L+ R CG+ A+ ++
Sbjct: 30 WGSWKGFHQKLYEPKQESWRRM-IWEKNLNKIKIHNLEHSLGKHTWRMGMNHFGDMTNEEFR-QKMNGYHGV--QPHKVSKGSTFLVPQNYEAPPTVDWRDKGLVTEVKDQGECGSCWAFSTTGALEGQHMRKVGQLVSLSEQNLVDCSRAEGNQGCGGGLMDQAFQYVKDNGGIDSEAAYPYTGTDGDKCHYDPKFNSANDTGFVDVTSGDEKALKIAVASVGPVSVAIDASHESFQFYQSGVY--FEPDCSSQDLDHGVLVVGYGVKGTGENGKKYWIVKNSWSPKWGDEGYVLMARNKKNHCGIATAASYPLV 339
BLAST of Cathepsin F vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007755.1 (pep scaffold:Pmarinus_7.0:GL476381:1843:17023:-1 gene:ENSPMAG00000007008.1 transcript:ENSPMAT00000007755.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 190.66 bits (483), Expect = 6.035e-56 Identity = 120/317 (37.85%), Postives = 174/317 (54.89%), Query Frame = 2
Query: 668 VSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRL-DKGSAVY--GVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKT----AQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDT--IDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASID--SSESFMANWCSVNGPISIGINAFAMQF--YRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGY-YLVYRGSGVCGLNKMATTSVI 1576
V L +D++K + K Y +E+E+A R +F N K+ L N L D+G+ + G+ ++SDL E+ + + ++L +R P +++ + VDWR G VT VK QG CGS WAFS TG++EGQ F T L SLSEQQLVDC +NGCNGG +A + I G++SE SYPY G C + +A + ++ S+E + + GPI+I +NA F Y+ G+ + S +PN H +L+VG+ S SG FWIVKNSWGE WGE GY Y++ CG+ + +I
Sbjct: 22 VQQLQWDTWKSTYGKHYGSEQEDAHRRDVFEQNLKRVLQHNLLADEGNVSFHLGINKYSDLELHEYHEKVVGRFWNLRNGTRRRG-APFPLRSMDNLPEQVDWRLKGYVTPVKEQGLCGSSWAFSATGSLEGQHFAATGNLTSLSEQQLVDCTKSYYNNGCNGGRSERALQYIIDNNGIDSELSYPYEHADGKCRFKPANVATKCSSYQFVEPSSNEEVLRQAVASVGPIAIAMNADLDTFKHYKSGLFNEPSCDKSPN---HAMLVVGYGS-LSGNDFWIVKNSWGEDWGEKGYIYMIRNKDNQCGIASIGIYPII 333
BLAST of Cathepsin F vs. Ensembl Nematostella
Match: EDO42751 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0K3]) HSP 1 Score: 346.28 bits (887), Expect = 2.555e-116 Identity = 165/279 (59.14%), Postives = 204/279 (73.12%), Query Frame = 2
Query: 746 FKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIP-QDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
KIF SN +KA M ++D G+A YG T FSDL++EEFR Q + P + + ++IP DI ++VDWR G VT VKNQGSCGSCWAFSTTGN+EGQ+ +KT +LVSLSEQ+LVDCDTID GC GGLPS AYK I+++GGLESE YPY C +K+++ V IN S I E +A W + NGPISIGINA AMQFY GGI+HP+ IFCNP+ L+HGVLIVG+ +G P+WI+KNSWG SWGE GYYL+YRG G CGLN M T++VI+
Sbjct: 1 MKIFESNMRKAAKMQKMDSGTAQYGPTIFSDLSEEEFRKQKMMPGWGKPLYEMKDAEIPLGDI--PESVDWRDKGVVTPVKNQGSCGSCWAFSTTGNIEGQYAIKTGKLVSLSEQELVDCDTIDKGCEGGLPSNAYKQIEKLGGLESESDYPYKGADSKCKFNKAEVKVTINSSVVISKDEKEIAAWLAKNGPISIGINANAMQFYMGGIAHPWKIFCNPSSLNHGVLIVGYG-VKNGTPYWIIKNSWGPSWGEKGYYLIYRGGGCCGLNTMCTSAVID 276
BLAST of Cathepsin F vs. Ensembl Nematostella
Match: EDO45953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRH6]) HSP 1 Score: 210.69 bits (535), Expect = 2.576e-63 Identity = 119/303 (39.27%), Postives = 172/303 (56.77%), Query Frame = 2
Query: 689 SFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLS--PAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAFAMQFYRGGI-SHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
++K K Y + EE R I+ N +K N D S + DLT++EFR YL ++ +KR P ++K +VDW G VT VKNQG CGSCWAFSTTG+VEGQ F KT LVSLSEQ L+DC +NGC GGL A++ I+ GG+++E SYPY +G+C S + + G I SE + + + GP+S+ ++A QFY G+ +P +C+ LDHGVL++G+ + +G+ +W+VKNSWG SWG GY ++ R + CG+ A+ ++
Sbjct: 29 AWKSYHGKSYSDVHEERTRMAIWQQNLEKIKRHNAEDH-SYKMAMNHLGDLTEDEFRYFYLGVRAHHNSTKRGWATYMPPSNVKIPSSVDWSQKGYVTGVKNQGQCGSCWAFSTTGSVEGQHFRKTGSLVSLSEQNLIDCSGSYGNNGCQGGLMDNAFRYIESNGGIDTESSYPYLGQQGSCHFSSSHVGARVTGYQDIPQGSEQALQSAVATVGPVSVAVDASQWQFYSSGVYDNP---YCSSTQLDHGVLVIGYGN-YNGQDYWLVKNSWGYSWGVEGYIMMSRNKNNQCGIASSASYPLV 326
BLAST of Cathepsin F vs. Ensembl Nematostella
Match: EDO36727 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHX1]) HSP 1 Score: 204.912 bits (520), Expect = 5.234e-61 Identity = 123/307 (40.07%), Postives = 167/307 (54.40%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYL---SPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAFAM--QFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
+ ++K K Y EE R I+ N KK + + + S + DLT +EFR Y S + +K+ P ++ VDWR G VT VKNQG CGSCWAFSTTG++EGQ F KT +LVSLSEQ LVDC T +NGC GGL A+K I++ GG+++E+SYPY A C KS I G + E + GPIS+ I+A M QFY G+ + + C+ LDHGVL+VG+ T G +W+VKNSWGE WG GY ++ R + CG+ A+ ++
Sbjct: 28 WQAWKLFHTKKYTTVTEEGARKAIWRDNLKK-IQKHNAEGHSFTLAMNHLGDLTQDEFRYFYTGMRSHYSNYTKKQGSAFLAPSHVQVPDTVDWRKEGYVTPVKNQGQCGSCWAFSTTGSLEGQNFKKTGKLVSLSEQNLVDCSTAYGNNGCQGGLMDYAFKYIKENGGIDTEESYPYEARNDRCRFQKSNIGAVDTGFVDVTHGDEEALKTAAGTVGPISVAIDAGHMSFQFYHSGVYN--NAGCSSTSLDHGVLVVGY-GTYQGSDYWLVKNSWGERWGMEGYIMMSRNKNNQCGVATQASYPLV 330
BLAST of Cathepsin F vs. Ensembl Nematostella
Match: EDO45852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL9]) HSP 1 Score: 202.216 bits (513), Expect = 5.547e-60 Identity = 126/321 (39.25%), Postives = 169/321 (52.65%), Query Frame = 2
Query: 641 VLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQI---PQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDS-SESFMANWCSVNGPISIGINA--FAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGS-GVCGLNKMATTSVI 1576
L +P E + N+ ++K K Y N+ EE R I+ +N KK + N K S + D+T E L Q P ++K ++DWR+ G VT VKNQG CGSCWAFSTTG +EGQ F KT +LVSLSEQ LVDC +NGC GGL A++ I++ GG+++E SYPY A G C +KS I G I + E+ + + GPISI I+A FY G+ C+ LDHGVL VG+ T G+ +W+VKNSWG SWGE GY + R CG+ A+ ++
Sbjct: 15 ALAMPPMEPLQDPNWKAWKSFHGKEYPNKNEETMRNFIWQNNLKKIVTHNE-GKHSFKLAMNHLGDMTSLEISQTLLGLKLKKHAESQPKGATFLPPANVKVVDSIDWRSKGYVTPVKNQGQCGSCWAFSTTGALEGQHFRKTGKLVSLSEQNLVDCSGKYGNNGCEGGLMDNAFQYIKENGGIDTEKSYPYLAKDGVCHYNKSAIGAKDTGFVDIPTGDENALQQALASVGPISIAIDASQSTFHFYHQGVYDDPD--CSSTRLDHGVLAVGY-GTDDGKDYWLVKNSWGPSWGEEGYIKIARNDHDKCGVASKASYPLV 331
BLAST of Cathepsin F vs. Ensembl Nematostella
Match: EDO46465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPY5]) HSP 1 Score: 189.504 bits (480), Expect = 2.443e-55 Identity = 120/314 (38.22%), Postives = 173/314 (55.10%), Query Frame = 2
Query: 662 EVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQ-IP-QDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASID-SSESFMANWCSVNGPISIGINA--FAMQFYRGGI-SHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
E+ + ++K K Y EEE+ +R I++ N + N + S + F+DLT EF+ +++ Y + S +P +++ VDWR G VTAVKNQG CGSCWAFS+TG++EGQ F KT +LVSLSEQ LVDC +NGC GGL A+K I+ G+++E SYPY A G C + + G + SE + + + GPIS+ I+A + Q Y+ G+ S P C+ LDHGVL VG+ + G+ +W+VKNSWGE WG NGY + R CG+ A+ ++
Sbjct: 20 ELSQDRQWHAWKDFHGKTYTGEEEDLRR-AIWNDNLEIVKKHN-AENHSYKLDMNHFADLTVTEFKQRFM--GYRAASNSTGGSTFLPLSNVQLPAEVDWRDKGFVTAVKNQGQCGSCWAFSSTGSLEGQHFRKTGKLVSLSEQNLVDCSKKYGNNGCEGGLMDYAFKYIKNNDGIDTEQSYPYTARDGQCHFKPGSVGATVTGYTDVQRGSEGDLQSAVATVGPISVAIDAGHSSFQLYKTGVYSEP---DCSSTQLDHGVLAVGYGA-EDGKDYWLVKNSWGEGWGMNGYIKMSRNKDNQCGIATQASYPLV 325
BLAST of Cathepsin F vs. Ensembl Medaka
Match: ctsf (cathepsin L [Source:NCBI gene;Acc:101161416]) HSP 1 Score: 343.969 bits (881), Expect = 4.120e-112 Identity = 185/440 (42.05%), Postives = 251/440 (57.05%), Query Frame = 2
Query: 302 DKDLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCR-NELKRSNQLLSECGLNENLAPKRAKLQIVSTPW----------LEPKHHFEVMSEIEEL--DLKLHDQLFVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAY-DLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVIN 1579
D L++V A +YN N+++ + S +Q+V GI Y V L T C+ + + R+ E + L + ++ PW PK E + + E + + + +LG F F + K Y ++EE +R +IF N K A + LD+GSA YGVT+FSDLT+EEFRS YL+P + P + DWR G V+ VKNQG CGSCWAFS TGN+EGQWFLK L+SLSEQ+LVDCD +D C GGLPS AY+AI+++GGLESE Y Y +K C K+A YIN S + E +A W + NGPIS+ +NAFAMQFY+ G+SHP+ IFCNP +DH VL+VG+ +G PFW +KNSWGE +GE GYY + RGS CG+N+M +++VIN
Sbjct: 48 DPGLKKVMLFAEERYNRGSNAMHLRKISRFVSATKQLVKGIRYTITVELSNTLCKKSAMVRTCDFYPE---TQKLKTEVCVFEVWDIPWQGTSTLLKQKCSPKAEVEETNRVAEPTNSQPVEESVQLLG----------QFKDFMVKYKKDYSSQEEAERRLQIFQENLKTAEKLQALDQGSAEYGVTKFSDLTEEEFRSTYLNPLLSQWTLHRGMKPAPPAKTPAPDSWDWRDHGAVSPVKNQGMCGSCWAFSVTGNIEGQWFLKNGTLLSLSEQELVDCDGLDQACRGGLPSNAYEAIEKLGGLESETDYSYTGHKQKCDFTNRKVAAYINSSVELPKDEREIAAWLAENGPISVALNAFAMQFYKKGVSHPWKIFCNPWMIDHAVLLVGYGE-RNGIPFWAIKNSWGEDYGEQGYYYLQRGSNACGINRMGSSAVIN 473
BLAST of Cathepsin F vs. Ensembl Medaka
Match: ctsl.1 (cathepsin L1 [Source:NCBI gene;Acc:101171789]) HSP 1 Score: 209.534 bits (532), Expect = 3.120e-62 Identity = 124/314 (39.49%), Postives = 183/314 (58.28%), Query Frame = 2
Query: 677 LNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRL-DKGSAVY--GVTQFSDLTDEEFR---SQYLSPAYD--LSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDC--DTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDS-SESFMANWCSVNGPISIGINA--FAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMATTSVI 1576
L F +++ F + Y + EEA+R + + +N K L+ N L D+G Y G+T F+D+ +EE++ SQ +++ L +R ++P++ AVDWR G VT VK+Q CGSCWAFS TG++EGQ F KT +LVSLSEQQLVDC D + GC GGL A++ IQ GG+++E+SYPY A G C + G + S E + + GPIS+GI+A + Q Y G+ C+ + LDHGVL VG+ S +G+ +W+VKNSWG +WG+ GY + + S CG+ A+ ++
Sbjct: 29 LEFHAWRLKFGRTYSSPTEEAQRRQTWLNNRKLVLVHNILADQGIKSYRLGMTYFADMENEEYKRLISQGCLGSFNASLPRRGSTFFRLPENKDLPAAVDWRDKGYVTDVKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNMGCGGGLMDDAFRYIQATGGIDTEESYPYEAEDGECRYKPDAVGATCTGYVDVSSGDEDALQEAVATIGPISVGIDASHISFQLYESGLYDEPQ--CSSSELDHGVLAVGYGS-ENGQDYWLVKNSWGLTWGDQGYIKMSKNKSNQCGIATAASYPLV 339
BLAST of Cathepsin F vs. Ensembl Medaka
Match: ctsk (cathepsin K [Source:NCBI gene;Acc:101164922]) HSP 1 Score: 202.986 bits (515), Expect = 7.653e-60 Identity = 127/341 (37.24%), Postives = 178/341 (52.20%), Query Frame = 2
Query: 590 VMSEIEELDLKLHDQLFVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNR---LDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQD-----IKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINAFAMQF--YRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSG-VCGLNKMATTSVI 1576
VMS+++E L H ++ +K K Y EEE R I+ N + N+ L + G+ QF D+T EE + L+ P+ +P + IK ++VD+R G VT+VKNQGSCGSCWAFS+ G +EGQ KT LV LS Q LVDC T ++GC GG + A+K +Q+ GG++SE +YPY C + S +A I G + + E +A GP+S+GI+A F Y+ GI F CN ++H VL VG+ G+ FWIVKNSWGE+WG GY L+ R G VCG+ +A+ V+
Sbjct: 15 VMSQMDETTLDAH------------------WEEWKMTHTKEYITVEEEGIRRAIWEKNLRMIEAHNQEAALGMHTYTLGMNQFGDMTQEEVVERMTGLQMPLNPEPR----VPMETDGSLIKLPKSVDYRKKGMVTSVKNQGSCGSCWAFSSVGALEGQLAKKTGNLVDLSPQNLVDCVTENDGCGGGYMTNAFKYVQENGGIDSEAAYPYMGEDQPCRYNVSGLAAQIKGYKEVPEGDEHALAVALFKAGPVSVGIDASQNSFLYYQKGIY--FDRNCNKEDINHAVLAVGYGVNAKGKKFWIVKNSWGETWGNKGYVLMARNRGNVCGIANLASYPVM 331
BLAST of Cathepsin F vs. Ensembl Medaka
Match: ctsl (cathepsin L [Source:NCBI gene;Acc:100049246]) HSP 1 Score: 192.971 bits (489), Expect = 5.424e-56 Identity = 124/304 (40.79%), Postives = 168/304 (55.26%), Query Frame = 2
Query: 722 NEEEEAKRFKIFHSNYKKALLMN---RLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQR-----ISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTID--NGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGN-CALDKSKIAVYINGSASIDSSE--SFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIVGF---NSTTSGEPFWIVKNSWGESWGENGY-YLVYRGSGVCGLNKMATTSVI 1576
+E+EE R ++ N +K L N + K S G+ F D+T EEFR + Y +R QR + P ++ +AVDWR G VT VK+QG CGSCWAFSTTG +EGQ F KT +LVSLSEQ LVDC + GCNGGL QA++ ++ GL+SED YPY C + AV G I S + + M SV GP+S+ I+A + QFY+ GI F C+ + LDHGVL+VG+ G+ +WIVKNSW E WG+ G+ Y+ CG+ A+ ++
Sbjct: 40 HEKEEGWRRLVWEKNLRKIELHNLEHSMGKHSYRLGMNHFGDMTHEEFRQ--IMNGY--KRREQRKYSGSLFMEPNFLEAPRAVDWRDKGYVTPVKDQGQCGSCWAFSTTGALEGQQFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDNQGLDSEDFYPYKGTDDQPCQYNAQYSAVNDTGFVDIPSGKERALMKAVASV-GPVSVAIDAGHESFQFYQSGIY--FEKECSSDELDHGVLVVGYGFEGEDVDGKKYWIVKNSWSEKWGDKGFIYMAKDRHNHCGIATAASYPLV 336
BLAST of Cathepsin F vs. Ensembl Medaka
Match: ctsh (cathepsin H [Source:NCBI gene;Acc:111947539]) HSP 1 Score: 181.415 bits (459), Expect = 7.059e-52 Identity = 109/294 (37.07%), Postives = 160/294 (54.42%), Query Frame = 2
Query: 731 EEAKRFKIFHSNYKKALLMNRLDKG--SAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQ-----AVDWRALGG-VTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDC--DTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDS-SESFMANWCSVNGPISIGINAFA-MQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVI 1576
E +R +IF N K L+++ ++G S + QFSD+T EFR +L PQ S + +++ ++DWR G +T VKNQG+CGSCW FSTTG +E + T +L+SLSEQQLVDC D ++GCNGGLPSQA++ I GL +E YPY A + C S A ++ ++ + E M + + + P+S + Y G+ + ++H VL VG+ +G P+WIVKNSWG WG +GY+L+ RG +CGL A+ V+
Sbjct: 41 EYHQRLQIFTENKK---LIDKHNEGNHSFTMALNQFSDMTFTEFRKAFLW------SEPQNCSATSGNHLSSKGPYPDSIDWRKKGNYITPVKNQGACGSCWTFSTTGCLESVTAIATGKLLSLSEQQLVDCAQDFNNHGCNGGLPSQAFEYIMYNKGLMTEQDYPYTAMEDKCMYKPSLAAAFVKEVVNVTAYDEMGMVDAVATHNPVSFAFEVTSDFMNYHQGVYTSTECHSTADKVNHAVLAVGYGQ-ENGTPYWIVKNSWGSKWGMDGYFLIERGKNMCGLAACASFPVV 324
BLAST of Cathepsin F vs. Planmine SMEST
Match: SMESG000005279.1 (SMESG000005279.1) HSP 1 Score: 948.347 bits (2450), Expect = 0.000e+0 Identity = 456/459 (99.35%), Postives = 458/459 (99.78%), Query Frame = 2
Query: 209 QTSTLFLFLINVGLLFGTGEKREISLSKLRKDKDLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSECGLNENLAPKRAKLQIVSTPWLEPKHHFEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLNFDSFKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVINLN 1585
QTSTLFLFLINVGLLFGTGEKREISLSKLRKDKDLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSECGLNENLAPKRAKLQIVSTPWLEPKHHFEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLNFDSFKK FNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGV+AVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFY+GGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVINLN
Sbjct: 3 QTSTLFLFLINVGLLFGTGEKREISLSKLRKDKDLQEVFREAINKYNSRVNSIYSYAPYQVHSIRQQVVAGILYEFEVTLVGTNCRNELKRSNQLLSECGLNENLAPKRAKLQIVSTPWLEPKHHFEVMSEIEELDLKLHDQLFVLGLPDGEVVSGLNFDSFKKKFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVSAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGINAFAMQFYQGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSGVCGLNKMATTSVINLN 461
BLAST of Cathepsin F vs. Planmine SMEST
Match: SMESG000049781.1 (SMESG000049781.1) HSP 1 Score: 211.46 bits (537), Expect = 3.513e-63 Identity = 122/301 (40.53%), Postives = 169/301 (56.15%), Query Frame = 2
Query: 692 FKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVY----GVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGIN-AFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGY-YLVYRGSGVCGLNKMATTSVI 1576
+ K +NK Y+N E R I+ N K + + LD +Y G+ QF+DLT EF++ YLS +K VDW G VT VK+QG CGSCWAFS TG++EGQ+F KT RLVS SEQQLVDC +NGC+GGL + A+ I+ +GG+ESE YPY A + NC + SK+ ++G ID +E +A + GPIS+GI+ + Q Y+ G+ + PN HGVL+VG+ T+ + +WIVKNSWG WG GY ++ C + A+ V+
Sbjct: 31 YMKIYNKTYENPFHELIRRMIWEDNLK-YIHKHNLDHDLGLYTFTLGINQFADLTHAEFKAIYLSGNLKPTKTGNTYLPPLNAFNVPANVDWTEKGYVTDVKDQGKCGSCWAFSATGSLEGQFFRKTGRLVSFSEQQLVDCSKSNNGCHGGLMTSAFNDIKDLGGIESEQEYPYKAQQLNCEFNHSKVVTSVSGYKEIDENEGSLAIAVANEGPISVGISVSLNFQLYKSGVYNEPDCSRVPN---HGVLVVGY-GTSVNDNYWIVKNSWGPLWGMKGYIWMSKDKDNQCAIASFASFPVV 326
BLAST of Cathepsin F vs. Planmine SMEST
Match: SMESG000049723.1 (SMESG000049723.1) HSP 1 Score: 211.075 bits (536), Expect = 4.443e-63 Identity = 127/310 (40.97%), Postives = 186/310 (60.00%), Query Frame = 2
Query: 683 FDSFKKNFNKLYQNEEEEAKRFKIFHSNYK---KALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQI--PQDIKT-AQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASI-DSSESFMANWCSVNGPISIGINA--FAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGYYLVYRGSG-VCGLNKMATTSVI 1576
++++K F K Y + E ++R I+ N K + L + L K + G+ F+D+T+EEFR+ YL + KR S P+++ +VDWR G VT VKNQ CGSCW+FSTTG++EGQ + KT+ L+S SEQQLVDC +NGC+GGL A++ IQQ G+E+E +YPY A GNC DKSK+ G + I +E +A+ + GPIS+ I+A ++ Q Y+ GI + C+ + LDHGVL +G+ T +G+ FW+VKNSWG WG GY + + G CG+ MA+ ++
Sbjct: 31 WEAYKTQFGKKYVSLNEISRRL-IWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLGVS---PKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQY-GIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQ--CSSSQLDHGVLAIGY-GTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGIATMASYPLV 332
BLAST of Cathepsin F vs. Planmine SMEST
Match: SMESG000049783.1 (SMESG000049783.1) HSP 1 Score: 208.764 bits (530), Expect = 3.355e-62 Identity = 119/279 (42.65%), Postives = 161/279 (57.71%), Query Frame = 2
Query: 692 FKKNFNKLYQNEEEEAKRFKIFHSNYKKALLMNRLDKGSAVY----GVTQFSDLTDEEFRSQYLSPAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTIDNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDSSESFMANWCSVNGPISIGIN-AFAMQFYRGGISHPFSIFCNPNHLDHGVLIVGFNSTTSGEPFWIVKNSWGESWGENGY 1513
+ K +NK Y+N E R I+ N K + + LD +Y G+ QF+DLT EF++ YLS +K VDW G VT VK+QG+CGSCWAFSTTG++EGQ+F KT RLVS SEQQLVDC +NGCNGGL + A+ I+ +GG+ESE YPY A + NC ++SK+ ++G I +E +A + GPIS+ I + Q Y+ G+ + PN H VL+VG+ T+ + +WIVKNSWG SWG GY
Sbjct: 31 YMKIYNKTYENPFHELIRRMIWEDNLK-YIHKHNLDHDLGLYTFTLGINQFADLTHAEFKAIYLSGNLRPTKTGNTYLPPLNAFNVPANVDWTEKGYVTDVKDQGNCGSCWAFSTTGSLEGQFFRKTGRLVSFSEQQLVDCSKSNNGCNGGLMTSAFNDIKDLGGIESEQEYPYQAQQLNCVFNRSKVVTSVSGYKEIYKNEGSLAIAVANEGPISVLIRVSLNFQLYKSGVYNEPDCSRVPN---HAVLVVGY-GTSVNDNYWIVKNSWGPSWGMKGY 304
BLAST of Cathepsin F vs. Planmine SMEST
Match: SMESG000049716.1 (SMESG000049716.1) HSP 1 Score: 206.068 bits (523), Expect = 4.108e-61 Identity = 129/303 (42.57%), Postives = 174/303 (57.43%), Query Frame = 2
Query: 692 FKKNFNKLYQNEEEEAKRFKIFHSNYK---KALLMNRLDKGSAVYGVTQFSDLTDEEFRSQYLS--PAYDLSKRPQRISQIPQDIKTAQAVDWRALGGVTAVKNQGSCGSCWAFSTTGNVEGQWFLKTKRLVSLSEQQLVDCDTI--DNGCNGGLPSQAYKAIQQMGGLESEDSYPYNANKGNCALDKSKIAVYINGSASIDS-SESFMANWCSVNGPISIGINAF--AMQFYRGGISHPFSIFCNPNHLDHGVLIVGFN-STTSGEPFWIVKNSWGESWGENGYYLVYRG-SGVCGLNKMAT 1564
+K FNK+Y +EE E R +I+ N + K + L + GV QF+DL+ +EF Y+ P +R + + + +K +V+W G VT VKNQ CGSCWAFSTTG++EGQ+F KT++LVS SEQQLVDC + GCNGG QA++ I + G+E E YPY A GNC K K+ ID SE +A + GPIS+GI+A + Q Y GGI S C+ LDHGVL VG+ SGE +W+VKNSWG+SWG NGY + + + CG+ MA+
Sbjct: 35 YKTKFNKVY-DEENEFVRRQIWEENLQFIQKHNIEYNLGRHKYTLGVNQFTDLSHQEFLDIYMKYRPIVKSVER-KSFDKKRKSLKLPNSVNWVKKGYVTPVKNQLQCGSCWAFSTTGSMEGQYFKKTRKLVSFSEQQLVDCSQSYGNEGCNGGFMDQAFQYIMKF-GIEKESVYPYTAMDGNCQYSKRKVITRCKNYTDIDQGSEEDLAEKLATVGPISVGIDASNPSFQSYNGGIYDEES--CSSTQLDHGVLAVGYGVDEDSGEKYWLVKNSWGDSWGLNGYIKMSKDKNNQCGIATMAS 332 The following BLAST results are available for this feature:
BLAST of Cathepsin F vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cathepsin F vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Cathepsin F vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Cathepsin F vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cathepsin F vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Cathepsin F vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cathepsin F vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cathepsin F vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cathepsin F vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Cathepsin F vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Cathepsin F vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Cathepsin F vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Cathepsin F vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Cathepsin F vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30027540 ID=SMED30027540|Name=Cathepsin F|organism=Schmidtea mediterranea sexual|type=transcript|length=1759bpback to top protein sequence of SMED30027540-orf-1 >SMED30027540-orf-1 ID=SMED30027540-orf-1|Name=SMED30027540-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=462bp MIQTSTLFLFLINVGLLFGTGEKREISLSKLRKDKDLQEVFREAINKYNSback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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