Succinate dehydrogenase cytochrome b560 subunit

Overview
NameSuccinate dehydrogenase cytochrome b560 subunit
Smed IDSMED30027474
Length (bp)1033
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Succinate dehydrogenase cytochrome b560 subunit (SMED30027474) t-SNE clustered cells

Violin plots show distribution of expression levels for Succinate dehydrogenase cytochrome b560 subunit (SMED30027474) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Succinate dehydrogenase cytochrome b560 subunit (SMED30027474) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Succinate dehydrogenase cytochrome b560 subunit (SMED30027474) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027474

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30027474h1SMcG0020758 Contig14538uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027474h1SMcG0020758 Contig14538newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30027474h1SMcG0020758 dd_Smed_v4_748_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30027474h1SMcG0020758 dd_Smed_v4_748_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30027474h1SMcG0020758 dd_Smed_v4_748_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30027474h1SMcG0020758 dd_Smed_v4_748_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30027474h1SMcG0020758 OX_Smed_1.0.15723ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Human
Match: SDHC (succinate dehydrogenase complex subunit C [Source:HGNC Symbol;Acc:HGNC:10682])

HSP 1 Score: 103.219 bits (256), Expect = 6.836e-26
Identity = 48/132 (36.36%), Postives = 74/132 (56.06%), Query Frame = 2 
Query:  164 KYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTG 559
            + C   +  +   A+ EM+ +W KN+   RP SPH+ IY   LPM  S+ HRGTGIA++      G+ A    G +   +  V SL L   +I++AK  + +PL++H  NG+RHL +D  +G  IP   ++G
Sbjct:   21 QLCIRNAVPLGTTAKEEMERFWNKNIGSNRPLSPHITIYSWSLPMAMSICHRGTGIALSAGVSLFGMSALLLPGNFESYLELVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLKIPQLYQSG 152
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Human
Match: SDHC (succinate dehydrogenase complex subunit C [Source:HGNC Symbol;Acc:HGNC:10682])

HSP 1 Score: 78.5666 bits (192), Expect = 3.786e-17
Identity = 38/101 (37.62%), Postives = 57/101 (56.44%), Query Frame = 2 
Query:  257 YSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTG 559
            +SP L I    LPM  S+ HRGTGIA++      G+ A    G +   +  V SL L   +I++AK  + +PL++H  NG+RHL +D  +G  IP   ++G
Sbjct:   18 FSPQLCIRNWSLPMAMSICHRGTGIALSAGVSLFGMSALLLPGNFESYLELVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLKIPQLYQSG 118
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Human
Match: SDHC (succinate dehydrogenase complex subunit C [Source:HGNC Symbol;Acc:HGNC:10682])

HSP 1 Score: 72.0182 bits (175), Expect = 5.368e-15
Identity = 35/96 (36.46%), Postives = 54/96 (56.25%), Query Frame = 2 
Query:  272 LIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTG 559
            L+    LPM  S+ HRGTGIA++      G+ A    G +   +  V SL L   +I++AK  + +PL++H  NG+RHL +D  +G  IP   ++G
Sbjct:    4 LLLSWSLPMAMSICHRGTGIALSAGVSLFGMSALLLPGNFESYLELVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLKIPQLYQSG 99
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Human
Match: SDHC (succinate dehydrogenase complex subunit C [Source:HGNC Symbol;Acc:HGNC:10682])

HSP 1 Score: 58.151 bits (139), Expect = 8.313e-10
Identity = 25/50 (50.00%), Postives = 33/50 (66.00%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWG 352
            A+ EM+ +W KN+   RP SPH+ IY   LPM  S+ HRGTGIA++   G
Sbjct:   34 AKEEMERFWNKNIGSNRPLSPHITIYSWSLPMAMSICHRGTGIALSADVG 83
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Celegans
Match: mev-1 (Succinate dehydrogenase cytochrome b560 subunit, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:P41956])

HSP 1 Score: 73.9442 bits (180), Expect = 1.660e-15
Identity = 45/146 (30.82%), Postives = 77/146 (52.74%), Query Frame = 2 
Query:  176 GTSEKVRLRAQTEMQDY-WE---KNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMA--IAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGF-DIPTTMRTGYIAIAVSIVLA 592
            GTS   +  A+T +Q + WE   K     RP +PHL +Y+ +L    S  HR +G  MA  +  GG+G     +   +   ++++ S +L   +    K I+ +P+IFH  NG+R L +D A+G  ++    ++GY+   +S +LA
Sbjct:   23 GTSIVTKSEAKTPIQKFGWEYLLKQRSKNRPIAPHLTVYQPQLTWMLSGFHRISGCVMAGTLLVGGIGFAVLPF--DFTAFVDFIRSWNLPCAVTAVFKYIIAFPIIFHTLNGIRFLGFDLAKGVNNVGQIYKSGYLVSGLSAILA 166
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Celegans
Match: mev-1 (Succinate dehydrogenase cytochrome b560 subunit, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:P41956])

HSP 1 Score: 73.9442 bits (180), Expect = 1.660e-15
Identity = 45/146 (30.82%), Postives = 77/146 (52.74%), Query Frame = 2 
Query:  176 GTSEKVRLRAQTEMQDY-WE---KNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMA--IAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGF-DIPTTMRTGYIAIAVSIVLA 592
            GTS   +  A+T +Q + WE   K     RP +PHL +Y+ +L    S  HR +G  MA  +  GG+G     +   +   ++++ S +L   +    K I+ +P+IFH  NG+R L +D A+G  ++    ++GY+   +S +LA
Sbjct:   23 GTSIVTKSEAKTPIQKFGWEYLLKQRSKNRPIAPHLTVYQPQLTWMLSGFHRISGCVMAGTLLVGGIGFAVLPF--DFTAFVDFIRSWNLPCAVTAVFKYIIAFPIIFHTLNGIRFLGFDLAKGVNNVGQIYKSGYLVSGLSAILA 166
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Celegans
Match: mev-1 (Succinate dehydrogenase cytochrome b560 subunit, mitochondrial [Source:UniProtKB/Swiss-Prot;Acc:P41956])

HSP 1 Score: 50.0618 bits (118), Expect = 1.209e-7
Identity = 29/99 (29.29%), Postives = 53/99 (53.54%), Query Frame = 2 
Query:  305 SLLHRGTGIAMA--IAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGF-DIPTTMRTGYIAIAVSIVLA 592
            S  HR +G  MA  +  GG+G     +   +   ++++ S +L   +    K I+ +P+IFH  NG+R L +D A+G  ++    ++GY+   +S +LA
Sbjct:    3 SGFHRISGCVMAGTLLVGGIGFAVLPF--DFTAFVDFIRSWNLPCAVTAVFKYIIAFPIIFHTLNGIRFLGFDLAKGVNNVGQIYKSGYLVSGLSAILA 99
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Fly
Match: SdhC (gene:FBgn0037873 transcript:FBtr0082372)

HSP 1 Score: 80.4925 bits (197), Expect = 8.761e-18
Identity = 57/174 (32.76%), Postives = 90/174 (51.72%), Query Frame = 2 
Query:   95 MGTFGARLLRNPQVFYPVRTQYLKYCCGT---SEKVRLRAQTEMQD-YWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFA 604
            M    + L+R+P +      Q L+    +   S KV   A+T+  + ++EKN +  R  SPHL IY+ +L    S+ HRGTG+A+ +   GLG+GA   +   +  +  V  L L+   + + K I+ +P  +H  NG+RHL +D  R   I     TGY  +A S VL+ + A
Sbjct:    1 MYALSSSLIRSPAL-----RQGLQMAAASRPVSMKVVSVAETQKDESFFEKNERLGRELSPHLTIYQPQLTSMLSICHRGTGLALGVGVWGLGLGALISSHDISHYVTMVEGLQLSGATLTALKFIIAYPAGYHTANGIRHLLWDTGRFLKIKEVYSTGYAMVATSFVLSAILA 169
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Fly
Match: SdhC (gene:FBgn0037873 transcript:FBtr0335221)

HSP 1 Score: 80.4925 bits (197), Expect = 8.761e-18
Identity = 57/174 (32.76%), Postives = 90/174 (51.72%), Query Frame = 2 
Query:   95 MGTFGARLLRNPQVFYPVRTQYLKYCCGT---SEKVRLRAQTEMQD-YWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFA 604
            M    + L+R+P +      Q L+    +   S KV   A+T+  + ++EKN +  R  SPHL IY+ +L    S+ HRGTG+A+ +   GLG+GA   +   +  +  V  L L+   + + K I+ +P  +H  NG+RHL +D  R   I     TGY  +A S VL+ + A
Sbjct:    1 MYALSSSLIRSPAL-----RQGLQMAAASRPVSMKVVSVAETQKDESFFEKNERLGRELSPHLTIYQPQLTSMLSICHRGTGLALGVGVWGLGLGALISSHDISHYVTMVEGLQLSGATLTALKFIIAYPAGYHTANGIRHLLWDTGRFLKIKEVYSTGYAMVATSFVLSAILA 169
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Fly
Match: CG6629 (gene:FBgn0037860 transcript:FBtr0082380)

HSP 1 Score: 65.855 bits (159), Expect = 4.882e-12
Identity = 40/131 (30.53%), Postives = 65/131 (49.62%), Query Frame = 2 
Query:  224 YWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVKL 616
            Y ++N+   R  SPHL IYK++L  T S   R +G  +A+    +G+      G     I  V   D    ++  AK+++  P  +H   G RHL +   +   IP    TGY+A+A++I L+    +VK+
Sbjct:   75 YDDRNMLLGRQLSPHLSIYKIQLTSTLSAFLRISGFVLAVFVWFVGISGLCLQGDMEGFIKKVEKCDCHG-MVTMAKVMVTMPFAYHTVAGTRHLIWYLNKFLTIPEIYATGYVAVALTIALSAFLLAVKV 204
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Zebrafish
Match: sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein [Source:ZFIN;Acc:ZDB-GENE-040801-26])

HSP 1 Score: 104.375 bits (259), Expect = 1.556e-26
Identity = 45/128 (35.16%), Postives = 74/128 (57.81%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIV 586
            +  EM  +W KN +  RP SPH+ IYK  +PM  S+ HRGTGIA++       + A      Y   ++ + SL      +  +K  + +P+++H  NG+RHLA+DA +GF IP   R+GY+ + ++++
Sbjct:   34 SNEEMDKFWAKNTRLNRPMSPHMTIYKWSVPMAMSISHRGTGIALSSGISAFALAALVLPESYPYYLDLIHSLTFGPQFLAFSKFALAFPVVYHTYNGIRHLAWDAGKGFKIPEVYRSGYVVLGLTVL 161
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Zebrafish
Match: sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein [Source:ZFIN;Acc:ZDB-GENE-040801-26])

HSP 1 Score: 104.375 bits (259), Expect = 1.556e-26
Identity = 45/128 (35.16%), Postives = 74/128 (57.81%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIV 586
            +  EM  +W KN +  RP SPH+ IYK  +PM  S+ HRGTGIA++       + A      Y   ++ + SL      +  +K  + +P+++H  NG+RHLA+DA +GF IP   R+GY+ + ++++
Sbjct:   34 SNEEMDKFWAKNTRLNRPMSPHMTIYKWSVPMAMSISHRGTGIALSSGISAFALAALVLPESYPYYLDLIHSLTFGPQFLAFSKFALAFPVVYHTYNGIRHLAWDAGKGFKIPEVYRSGYVVLGLTVL 161
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Zebrafish
Match: sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein [Source:ZFIN;Acc:ZDB-GENE-040801-26])

HSP 1 Score: 104.375 bits (259), Expect = 1.556e-26
Identity = 45/128 (35.16%), Postives = 74/128 (57.81%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIV 586
            +  EM  +W KN +  RP SPH+ IYK  +PM  S+ HRGTGIA++       + A      Y   ++ + SL      +  +K  + +P+++H  NG+RHLA+DA +GF IP   R+GY+ + ++++
Sbjct:   34 SNEEMDKFWAKNTRLNRPMSPHMTIYKWSVPMAMSISHRGTGIALSSGISAFALAALVLPESYPYYLDLIHSLTFGPQFLAFSKFALAFPVVYHTYNGIRHLAWDAGKGFKIPEVYRSGYVVLGLTVL 161
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Zebrafish
Match: sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein [Source:ZFIN;Acc:ZDB-GENE-040801-26])

HSP 1 Score: 103.99 bits (258), Expect = 1.724e-26
Identity = 46/136 (33.82%), Postives = 78/136 (57.35%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASV 610
            +  EM  +W KN +  RP SPH+ IYK  +PM  S+ HRGTGIA++       + A      Y   ++ + SL      +  +K  + +P+++H  NG+RHLA+DA +GF IP   R+GY+ + ++++ +   A++
Sbjct:   32 SNEEMDKFWAKNTRLNRPMSPHMTIYKWSVPMAMSISHRGTGIALSSGISAFALAALVLPESYPYYLDLIHSLTFGPQFLAFSKFALAFPVVYHTYNGIRHLAWDAGKGFKIPEVYRSGYVVLGLTVLTSIGLAAM 167
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Zebrafish
Match: sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein [Source:ZFIN;Acc:ZDB-GENE-040801-26])

HSP 1 Score: 103.99 bits (258), Expect = 1.724e-26
Identity = 46/136 (33.82%), Postives = 78/136 (57.35%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASV 610
            +  EM  +W KN +  RP SPH+ IYK  +PM  S+ HRGTGIA++       + A      Y   ++ + SL      +  +K  + +P+++H  NG+RHLA+DA +GF IP   R+GY+ + ++++ +   A++
Sbjct:   32 SNEEMDKFWAKNTRLNRPMSPHMTIYKWSVPMAMSISHRGTGIALSSGISAFALAALVLPESYPYYLDLIHSLTFGPQFLAFSKFALAFPVVYHTYNGIRHLAWDAGKGFKIPEVYRSGYVVLGLTVLTSIGLAAM 167
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Xenopus
Match: urb1 (URB1 ribosome biogenesis 1 homolog (S. cerevisiae) [Source:Xenbase;Acc:XB-GENE-5817921])

HSP 1 Score: 117.472 bits (293), Expect = 4.068e-31
Identity = 62/157 (39.49%), Postives = 86/157 (54.78%), Query Frame = 2 
Query:  146 VRTQYLKYCCGTSEKVRL--RAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASV 610
            +RTQ     C T   V +   AQ EM  +W KN +  RP SPH+ IYK  LPM  S+ HRGTGIAM       G+ A    G +A  +  V SL L   +IYSAK  + +PL +H  NG+RHL +D  +G  IP   R+G   +A++++     A++
Sbjct:   35 LRTQLTPLLC-TRHVVPMGTTAQQEMDRFWNKNTRLNRPLSPHITIYKWSLPMAMSISHRGTGIAMTAGVSLFGLAALVLPGDFASYLELVKSLSLGPALIYSAKFALAFPLTYHVWNGIRHLTWDLGKGLKIPQVYRSGVTVLALTLITTATLAAM 190
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Mouse
Match: Sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein [Source:MGI Symbol;Acc:MGI:1913302])

HSP 1 Score: 108.227 bits (269), Expect = 4.920e-28
Identity = 51/132 (38.64%), Postives = 76/132 (57.58%), Query Frame = 2 
Query:  164 KYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTG 559
            + C   +  +   A+ EM+ +W+KN    RP SPHL IYK  LPM  S+ HRG+GIA++      G+ A    G +   + +V SL L   +IYSAK ++ +PL++H  NG+RHL +D  +G  IP    +G
Sbjct:   21 QLCIRNAAPLGTTAKEEMERFWKKNTSSNRPLSPHLTIYKWSLPMALSVCHRGSGIALSGGVSLFGLSALLLPGNFESYLMFVKSLCLGPTLIYSAKFVLVFPLMYHSLNGIRHLLWDLGKGLAIPQVWLSG 152
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Mouse
Match: Sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein [Source:MGI Symbol;Acc:MGI:1913302])

HSP 1 Score: 76.6406 bits (187), Expect = 1.002e-16
Identity = 38/100 (38.00%), Postives = 57/100 (57.00%), Query Frame = 2 
Query:  260 SPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTG 559
            +  L I K  LPM  S+ HRG+GIA++      G+ A    G +   + +V SL L   +IYSAK ++ +PL++H  NG+RHL +D  +G  IP    +G
Sbjct:   19 NAQLCIRKWSLPMALSVCHRGSGIALSGGVSLFGLSALLLPGNFESYLMFVKSLCLGPTLIYSAKFVLVFPLMYHSLNGIRHLLWDLGKGLAIPQVWLSG 118
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. UniProt/SwissProt
Match: sp|D0VWV4|C560_PIG (Succinate dehydrogenase cytochrome b560 subunit, mitochondrial OS=Sus scrofa OX=9823 GN=SDHC PE=1 SV=2)

HSP 1 Score: 108.997 bits (271), Expect = 2.363e-27
Identity = 51/149 (34.23%), Postives = 85/149 (57.05%), Query Frame = 2 
Query:  164 KYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASV 610
            + C   +  +   A+ EM+ +W KNL   RP SPH+ IY+  LPM  S+ HRGTGIA++      G+ A    G +   +  V SL L   +IY+AK  + +PL++H  NG+RHL +D  +G  IP   ++G + + ++++ +   A++
Sbjct:   21 QLCIRNAVPLGTTAKEEMERFWNKNLGSNRPLSPHITIYRWSLPMAMSICHRGTGIALSAGVSLFGLSALLLPGNFESHLELVKSLCLGPTLIYTAKFGIVFPLMYHTWNGIRHLIWDLGKGLTIPQLTQSGVVVLILTVLSSVGLAAM 169
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. UniProt/SwissProt
Match: sp|Q9CZB0|C560_MOUSE (Succinate dehydrogenase cytochrome b560 subunit, mitochondrial OS=Mus musculus OX=10090 GN=Sdhc PE=1 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 3.441e-27
Identity = 51/132 (38.64%), Postives = 76/132 (57.58%), Query Frame = 2 
Query:  164 KYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTG 559
            + C   +  +   A+ EM+ +W+KN    RP SPHL IYK  LPM  S+ HRG+GIA++      G+ A    G +   + +V SL L   +IYSAK ++ +PL++H  NG+RHL +D  +G  IP    +G
Sbjct:   21 QLCIRNAAPLGTTAKEEMERFWKKNTSSNRPLSPHLTIYKWSLPMALSVCHRGSGIALSGGVSLFGLSALLLPGNFESYLMFVKSLCLGPTLIYSAKFVLVFPLMYHSLNGIRHLLWDLGKGLAIPQVWLSG 152
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. UniProt/SwissProt
Match: sp|P70097|C560_CRIGR (Succinate dehydrogenase cytochrome b560 subunit, mitochondrial OS=Cricetulus griseus OX=10029 GN=SDHC PE=2 SV=1)

HSP 1 Score: 107.842 bits (268), Expect = 5.503e-27
Identity = 50/138 (36.23%), Postives = 81/138 (58.70%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVKL 616
            A+ EM+ +W KN    RP SPHL IY+  LPM  S+ HRGTG+A++      G+ A    G +   + ++ SL L   +I+SAK ++ +PL++H  NG+RHL +D  +G  I    ++G     V++++  + +SV L
Sbjct:   34 AKEEMERFWNKNTSSKRPVSPHLTIYRWSLPMVMSICHRGTGVALSGGVSLFGLSALLLPGNFESYLMFIKSLCLGPALIHSAKFVLVFPLMYHSLNGIRHLIWDLGKGLSISQVYQSG-----VAVLMLAVLSSVGL 166
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. UniProt/SwissProt
Match: sp|Q99643|C560_HUMAN (Succinate dehydrogenase cytochrome b560 subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHC PE=1 SV=1)

HSP 1 Score: 103.219 bits (256), Expect = 3.283e-25
Identity = 48/132 (36.36%), Postives = 74/132 (56.06%), Query Frame = 2 
Query:  164 KYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTG 559
            + C   +  +   A+ EM+ +W KN+   RP SPH+ IY   LPM  S+ HRGTGIA++      G+ A    G +   +  V SL L   +I++AK  + +PL++H  NG+RHL +D  +G  IP   ++G
Sbjct:   21 QLCIRNAVPLGTTAKEEMERFWNKNIGSNRPLSPHITIYSWSLPMAMSICHRGTGIALSAGVSLFGMSALLLPGNFESYLELVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLKIPQLYQSG 152
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. UniProt/SwissProt
Match: sp|P35720|C560_BOVIN (Succinate dehydrogenase cytochrome b560 subunit, mitochondrial OS=Bos taurus OX=9913 GN=SDHC PE=1 SV=2)

HSP 1 Score: 102.064 bits (253), Expect = 9.358e-25
Identity = 52/151 (34.44%), Postives = 84/151 (55.63%), Query Frame = 2 
Query:  164 KYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVKL 616
            + C   +  +   A+ EM+ +W KN    RP SPH+ IY   LPM  S+ HRGTGIA++      G+ A    G +   + +V SL L   +I++AK  + +PL++H  NG+RHL +D  +G  I    ++G     V++++ T+ +SV L
Sbjct:   21 QLCIRNAVPLGTTAKEEMERFWSKNTTLNRPLSPHISIYGWSLPMAMSICHRGTGIALSAGVSLFGLSALLVPGSFESHLEFVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLTISQLHQSG-----VAVLVLTVLSSVGL 166
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. TrEMBL
Match: A0A0R3WQX3 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS3148 PE=4 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 4.331e-49
Identity = 79/157 (50.32%), Postives = 108/157 (68.79%), Query Frame = 2 
Query:  143 PVRTQYLKYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVK 613
            PV +   +Y   TSE+VRL+AQ+EMQDYWE+N+K  RP+SPHL IY   L M  S LHR TGIAMAI W G GV  FWYTG +  +++YV+   +   +I+ AK ++ +PL++HYTNGMRHLA+D A GFD+ T   TG   + +S++L    AS++
Sbjct:   36 PVLSMAKQYKGSTSEEVRLKAQSEMQDYWERNIKLKRPWSPHLTIYSPPLCMQNSFLHRATGIAMAIVWMGAGVSGFWYTGHFDAMLDYVNGFSIGPSLIFGAKCLLAYPLVYHYTNGMRHLAWDYAIGFDMKTVNLTGSTVLILSVLLTLALASIR 192
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. TrEMBL
Match: A0A0R3TUG1 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS11384 PE=4 SV=1)

HSP 1 Score: 171.4 bits (433), Expect = 1.367e-48
Identity = 80/148 (54.05%), Postives = 103/148 (69.59%), Query Frame = 2 
Query:  176 GTS-EKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVKL 616
            GTS E+VRL+AQTEMQDYWEKNLK  RP SPH  IY   L M TS +HR TG+AMA+AW   G   FWYTG +  ++ YV+S    + ++Y AK ++ +PL++HYTNGMRHLA+D A GFD+ T   TG   + +S V+  L AS+KL
Sbjct:   47 GTSPEEVRLQAQTEMQDYWEKNLKLKRPLSPHATIYSPPLCMATSFMHRATGVAMALAWMSAGCAGFWYTGNFDAMLEYVNSFQFGSTVLYGAKFLLAYPLVYHYTNGMRHLAWDYAIGFDMKTVNLTGSTNLMMSFVITALLASIKL 194
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. TrEMBL
Match: W6UVT2 (Succinate dehydrogenase cytochrome b560 subunit OS=Echinococcus granulosus OX=6210 GN=EGR_02629 PE=4 SV=1)

HSP 1 Score: 169.859 bits (429), Expect = 5.020e-48
Identity = 77/157 (49.04%), Postives = 106/157 (67.52%), Query Frame = 2 
Query:  143 PVRTQYLKYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVK 613
            PV +    Y   TSE+VRL+A++EMQDYWE+N+K  RP+SPH+LIY   L M  S LHR TG+AMAI W G G   FWYTG +  +++YVSS      I++ AK ++ +PL++HY NGMRHLA+D A GFD+ T   TG   + +S++L    AS++
Sbjct:   37 PVLSATKHYKGSTSEEVRLKAESEMQDYWERNIKLKRPWSPHILIYSPPLCMRNSFLHRATGVAMAIVWMGAGAAGFWYTGHFDGMLDYVSSFSFGPSIVFGAKCLLAYPLVYHYCNGMRHLAWDYAIGFDMKTVNMTGATVLILSVLLTLALASIR 193
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. TrEMBL
Match: A0A068WHC7 (Succinate dehydrogenase complex subunit C OS=Echinococcus granulosus OX=6210 GN=EgrG_000980600 PE=4 SV=1)

HSP 1 Score: 169.859 bits (429), Expect = 7.049e-48
Identity = 77/157 (49.04%), Postives = 106/157 (67.52%), Query Frame = 2 
Query:  143 PVRTQYLKYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVK 613
            PV +    Y   TSE+VRL+A++EMQDYWE+N+K  RP+SPH+LIY   L M  S LHR TG+AMAI W G G   FWYTG +  +++YVSS      I++ AK ++ +PL++HY NGMRHLA+D A GFD+ T   TG   + +S++L    AS++
Sbjct:   46 PVLSATKHYKGSTSEEVRLKAESEMQDYWERNIKLKRPWSPHILIYSPPLCMRNSFLHRATGVAMAIVWMGAGAAGFWYTGHFDGMLDYVSSFSFGPSIVFGAKCLLAYPLVYHYCNGMRHLAWDYAIGFDMKTVNMTGATVLILSVLLTLALASIR 202
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. TrEMBL
Match: A0A1Z4EAX1 (Cytochrome b large subunit of complex II OS=Echinococcus multilocularis OX=6211 GN=SDHA PE=2 SV=1)

HSP 1 Score: 169.088 bits (427), Expect = 1.252e-47
Identity = 77/157 (49.04%), Postives = 105/157 (66.88%), Query Frame = 2 
Query:  143 PVRTQYLKYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVK 613
            PV +    Y   TSE+VRL+A++EMQDYWE+N+K  RP+SPH+LIY   L M  S LHR TG+AMAI W G G   FWYTG +  +++YVSS      I++ AK ++ +PL++HY NGMRHLA+D A GFD+ T   TG   + +S +L    AS++
Sbjct:   37 PVLSATKHYKGSTSEEVRLKAESEMQDYWERNIKLKRPWSPHILIYSPPLCMRNSFLHRATGVAMAIVWMGAGAAGFWYTGHFDGMLDYVSSFSFGPSIVFGAKCLLAYPLVYHYCNGMRHLAWDYAIGFDMKTVNMTGATVLILSFLLTLALASIR 193
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Cavefish
Match: sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein [Source:ZFIN;Acc:ZDB-GENE-040801-26])

HSP 1 Score: 98.5969 bits (244), Expect = 9.270e-25
Identity = 45/123 (36.59%), Postives = 68/123 (55.28%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAI 571
            AQ EM  +W KN +  RP SPH+ IY+  +PM  S+ HRGTG+A++       V A    G +   ++ + SL     +I  +K  + +P+ +H  NG+RHL +DA +G  IP    +GY  I
Sbjct:    5 AQEEMNKFWAKNTRLNRPMSPHISIYRWSVPMAMSITHRGTGVALSGGISVFAVAALVLPGSFPHYLDLIHSLSFGPALITLSKFALSFPVAYHTFNGIRHLVWDAGKGLKIPEVYGSGYTVI 127
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Cavefish
Match: sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein [Source:ZFIN;Acc:ZDB-GENE-040801-26])

HSP 1 Score: 66.6254 bits (161), Expect = 2.366e-13
Identity = 31/95 (32.63%), Postives = 50/95 (52.63%), Query Frame = 2 
Query:  287 ELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAI 571
             +PM  S+ HRGTG+A++       V A    G +   ++ + SL     +I  +K  + +P+ +H  NG+RHL +DA +G  IP    +GY  I
Sbjct:   16 SVPMAMSITHRGTGVALSGGISVFAVAALVLPGSFPHYLDLIHSLSFGPALITLSKFALSFPVAYHTFNGIRHLVWDAGKGLKIPEVYGSGYTVI 110
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Cavefish
Match: sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein [Source:ZFIN;Acc:ZDB-GENE-040801-26])

HSP 1 Score: 62.7734 bits (151), Expect = 7.018e-12
Identity = 31/99 (31.31%), Postives = 51/99 (51.52%), Query Frame = 2 
Query:  287 ELPMTTSLLHRGTGIAMAIAWGG----LGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAI 571
             +PM  S+ HRGTG+A++  +        V A    G +   ++ + SL     +I  +K  + +P+ +H  NG+RHL +DA +G  IP    +GY  I
Sbjct:   16 SVPMAMSITHRGTGVALSGVFSPGISVFAVAALVLPGSFPHYLDLIHSLSFGPALITLSKFALSFPVAYHTFNGIRHLVWDAGKGLKIPEVYGSGYTVI 114
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Sea Lamprey
Match: SDHC (succinate dehydrogenase complex subunit C [Source:HGNC Symbol;Acc:HGNC:10682])

HSP 1 Score: 124.02 bits (310), Expect = 9.159e-35
Identity = 52/136 (38.24%), Postives = 87/136 (63.97%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASV 610
            A+ EM  +W+KN +  RP SPH+ IY+  +PM  S+ HRGTG+A++       + A  + G +A  + +V +L+L + +IY  K I+ WP ++H  NG+RHLA+DA +GF IP   ++GY  +A++ + A + A++
Sbjct:   33 AKKEMDTFWDKNTQLQRPLSPHVSIYRWSVPMLMSITHRGTGVALSGGVSAFALAALLFPGDFATKLEFVKNLELNSTLIYMGKFIIAWPFMYHSWNGIRHLAWDAGKGFKIPQVSQSGYFVLALTFITAGIVAAL 168
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Yeast
Match: SHH3 (Putative mitochondrial inner membrane protein of unknown function; although similar to paralogous Sdh3p, Shh3p is not a stoichiometric subunit of either succinate dehydrogenase or of the TIM22 translocase; SHH3 has a paralog, SDH3, that arose from the whole genome duplication [Source:SGD;Acc:S000004724])

HSP 1 Score: 49.6766 bits (117), Expect = 1.209e-7
Identity = 38/144 (26.39%), Postives = 61/144 (42.36%), Query Frame = 2 
Query:  200 RAQTEMQDYWEKN--------LKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGG----LGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLAT 595
              +    D W  N         +  RP SPHL +Y+ E+    S LHR +G+ +A+ +      LGV          + +N      +     + AK    +   FH+ NG+RHL +D          ++TG I +A ++VL T
Sbjct:   48 NGRVSKSDLWSSNKEEELLVSQRKKRPISPHLTVYEPEMSWYLSSLHRISGVLLALGFYAFTITLGVTTIMGMDTTFQDLNKWYHEKMPKWSQWVAKGSAAYLFAFHFGNGIRHLIWDMGYELTNRGVIKTGSIVLAGTLVLGT 191
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Yeast
Match: SDH3 (Subunit of succinate dehydrogenase and of TIM22 translocase; functions as cytochrome b subunit of succinate dehydrogenase, which couples oxidation of succinate to transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain; also required for mitochondrial inner membrane protein import as part of the TIM22 complex; SDH3 has a paralog, SHH3, that arose from the whole genome duplication [Source:SGD;Acc:S000001624])

HSP 1 Score: 46.2098 bits (108), Expect = 1.644e-6
Identity = 41/160 (25.62%), Postives = 65/160 (40.62%), Query Frame = 2 
Query:  134 VFYPVRTQYLKYC--CGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAW----GGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLAT 595
            +F   RT +L        + ++  +A    +    K  +  RP SPHL IY+ +L    S LHR + + M + +       GV      G   E ++       +    +S K    +    HY   +RHL +D A+   +    RTGY  I  + VL T
Sbjct:   35 LFNTARTNFLSTSPLKNVASEMNTKAAIAEEQILNKQ-RAKRPISPHLTIYQPQLTWYLSSLHRISLVLMGLGFYLFTILFGVSGLLGLGLTTEKVSNWYHQKFSKITEWSIKGSFAYLFAIHYGGAIRHLIWDTAKELTLKGVYRTGYALIGFTAVLGT 193
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Nematostella
Match: EDO38369 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SD28])

HSP 1 Score: 88.1965 bits (217), Expect = 5.257e-21
Identity = 49/155 (31.61%), Postives = 78/155 (50.32%), Query Frame = 2 
Query:  110 ARLLRNPQVFYPVRTQYLKYCC--GTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIA 568
            A +LR+   F  +R   L+  C    S  +   A ++ +D+++KN +  RP SP LL YK E P   S  HR TG+ M        + A          +N +   +L  P I++ K ++ WP+ +H  NG+RHL +D  +GF+I T  +TG + 
Sbjct:    2 ALMLRSSARF--LRPTVLRQSCILARSLPMATAADSKKEDFFKKNERLKRPMSPFLLTYKFEFPALLSGSHRVTGVIMTTGTTIFALCALGLPEGLEHYVNVIKGWELPRPFIFTCKTLLAWPVCYHGLNGLRHLFWDIGKGFEIKTLYKTGTVV 154
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Medaka
Match: sdhc (succinate dehydrogenase complex subunit C [Source:NCBI gene;Acc:101162241])

HSP 1 Score: 105.531 bits (262), Expect = 4.680e-27
Identity = 49/134 (36.57%), Postives = 77/134 (57.46%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFA 604
            A+ EM  +W KN +  RP SPHL IYK  +PM  S+ HRGTG+A++         A    G Y   ++ + SL +   +I  AK  + +P+ +H  NG+RHL +D  +GF +P   R+GY+ I +S++ + + A
Sbjct:   34 AKEEMNKFWAKNSRLNRPMSPHLAIYKWSVPMLMSITHRGTGLALSGGISAFAAAALVLPGNYPYYLDLIHSLSVGPVLIGLAKFGIAFPVSYHTYNGIRHLCWDLGKGFRLPEVNRSGYVVIGLSVITSIVLA 167
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Medaka
Match: sdhc (succinate dehydrogenase complex subunit C [Source:NCBI gene;Acc:101162241])

HSP 1 Score: 80.4925 bits (197), Expect = 1.056e-17
Identity = 40/108 (37.04%), Postives = 58/108 (53.70%), Query Frame = 2 
Query:  203 AQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAAR 526
            A+ EM  +W KN +  RP SPHL IYK  +PM  S+ HRGTG+A++         A    G Y   ++ + SL +   +I  AK  + +P+ +H  NG+RHL     R
Sbjct:   34 AKEEMNKFWAKNSRLNRPMSPHLAIYKWSVPMLMSITHRGTGLALSGGISAFAAAALVLPGNYPYYLDLIHSLSVGPVLIGLAKFGIAFPVSYHTYNGIRHLVRSMIR 141
[Close]
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Planmine SMEST
Match: SMESG000017174.1 (SMESG000017174.1)

HSP 1 Score: 379.793 bits (974), Expect = 3.371e-134
Identity = 183/183 (100.00%), Postives = 183/183 (100.00%), Query Frame = 2 
Query:   68 MSMILKGIRMGTFGARLLRNPQVFYPVRTQYLKYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVKL 616
            MSMILKGIRMGTFGARLLRNPQVFYPVRTQYLKYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVKL
Sbjct:    1 MSMILKGIRMGTFGARLLRNPQVFYPVRTQYLKYCCGTSEKVRLRAQTEMQDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVGAFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYDAARGFDIPTTMRTGYIAIAVSIVLATLFASVKL 183
The following BLAST results are available for this feature:
BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
SDHC6.836e-2636.36succinate dehydrogenase complex subunit C [Source:... [more]
SDHC3.786e-1737.62succinate dehydrogenase complex subunit C [Source:... [more]
SDHC5.368e-1536.46succinate dehydrogenase complex subunit C [Source:... [more]
SDHC8.313e-1050.00succinate dehydrogenase complex subunit C [Source:... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
mev-11.660e-1530.82Succinate dehydrogenase cytochrome b560 subunit, m... [more]
mev-11.660e-1530.82Succinate dehydrogenase cytochrome b560 subunit, m... [more]
mev-11.209e-729.29Succinate dehydrogenase cytochrome b560 subunit, m... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
SdhC8.761e-1832.76gene:FBgn0037873 transcript:FBtr0082372[more]
SdhC8.761e-1832.76gene:FBgn0037873 transcript:FBtr0335221[more]
CG66294.882e-1230.53gene:FBgn0037860 transcript:FBtr0082380[more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sdhc1.556e-2635.16succinate dehydrogenase complex, subunit C, integr... [more]
sdhc1.556e-2635.16succinate dehydrogenase complex, subunit C, integr... [more]
sdhc1.556e-2635.16succinate dehydrogenase complex, subunit C, integr... [more]
sdhc1.724e-2633.82succinate dehydrogenase complex, subunit C, integr... [more]
sdhc1.724e-2633.82succinate dehydrogenase complex, subunit C, integr... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
urb14.068e-3139.49URB1 ribosome biogenesis 1 homolog (S. cerevisiae)... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Sdhc4.920e-2838.64succinate dehydrogenase complex, subunit C, integr... [more]
Sdhc1.002e-1638.00succinate dehydrogenase complex, subunit C, integr... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|D0VWV4|C560_PIG2.363e-2734.23Succinate dehydrogenase cytochrome b560 subunit, m... [more]
sp|Q9CZB0|C560_MOUSE3.441e-2738.64Succinate dehydrogenase cytochrome b560 subunit, m... [more]
sp|P70097|C560_CRIGR5.503e-2736.23Succinate dehydrogenase cytochrome b560 subunit, m... [more]
sp|Q99643|C560_HUMAN3.283e-2536.36Succinate dehydrogenase cytochrome b560 subunit, m... [more]
sp|P35720|C560_BOVIN9.358e-2534.44Succinate dehydrogenase cytochrome b560 subunit, m... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3WQX34.331e-4950.32Uncharacterized protein OS=Hydatigena taeniaeformi... [more]
A0A0R3TUG11.367e-4854.05Uncharacterized protein OS=Rodentolepis nana OX=10... [more]
W6UVT25.020e-4849.04Succinate dehydrogenase cytochrome b560 subunit OS... [more]
A0A068WHC77.049e-4849.04Succinate dehydrogenase complex subunit C OS=Echin... [more]
A0A1Z4EAX11.252e-4749.04Cytochrome b large subunit of complex II OS=Echino... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
sdhc9.270e-2536.59succinate dehydrogenase complex, subunit C, integr... [more]
sdhc2.366e-1332.63succinate dehydrogenase complex, subunit C, integr... [more]
sdhc7.018e-1231.31succinate dehydrogenase complex, subunit C, integr... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
SDHC9.159e-3538.24succinate dehydrogenase complex subunit C [Source:... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
SHH31.209e-726.39Putative mitochondrial inner membrane protein of u... [more]
SDH31.644e-625.63Subunit of succinate dehydrogenase and of TIM22 tr... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO383695.257e-2131.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
sdhc4.680e-2736.57succinate dehydrogenase complex subunit C [Source:... [more]
sdhc1.056e-1737.04succinate dehydrogenase complex subunit C [Source:... [more]
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BLAST of Succinate dehydrogenase cytochrome b560 subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000017174.13.371e-134100.00SMESG000017174.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027474 ID=SMED30027474|Name=Succinate dehydrogenase cytochrome b560 subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1033bp
CGAATCTATTTGTATATATTTTTCTCTGTATTTTTAATTACGTGATTTCG
TATATTTGACTTTAACAATGTCCATGATATTAAAGGGCATAAGAATGGGA
ACTTTTGGGGCTAGATTGCTTCGTAACCCCCAAGTATTTTATCCGGTTCG
AACACAATATTTGAAATATTGCTGTGGAACTAGTGAAAAAGTTAGATTAA
GAGCCCAAACTGAAATGCAAGATTATTGGGAAAAGAATTTAAAGGGTCCC
AGGCCATATTCGCCTCATTTATTAATTTACAAAATGGAATTACCAATGAC
AACATCTCTTCTTCATCGAGGTACCGGGATAGCAATGGCCATAGCATGGG
GAGGACTGGGAGTTGGAGCATTCTGGTACACAGGACAATACGCTGAGTTA
ATTAATTATGTCTCATCATTGGATCTTGCAACACCAATTATTTATAGCGC
CAAATTAATAATGTGTTGGCCTTTGATTTTTCATTATACTAATGGAATGA
GACATTTGGCATATGATGCAGCAAGAGGATTCGACATCCCAACAACAATG
AGAACTGGATATATTGCAATCGCTGTCTCCATTGTCCTGGCAACGCTATT
TGCGTCCGTTAAGTTGTAAATGTTTCACCGCGCCATTCGATATTTGTGAA
TTTATATTATTAATAAAACGCTTAATTAGTGAATAATAAGTTTTCGAAAG
GATTTTCAATAACTATTTCTGTGTTGCATCAATAAATTATCTGTATGCAT
TCTAGATATCCTCCAATGGGGCGGCGGATGCGCTCGCCTCTTTATGCTTG
TTGTTGTCTGAATTATTATTATCATTATATTTTGTTATTGATTTTGGAGC
ATTATGAGTTCCTAATTGTGTTCTATATTTTAATTAACCTTAATATTTTG
TTTTAATTATGTCTAATAATCCGAATCAATAGGCGTAAATGCAGATTCTA
GATTATTGGAGAAATGTGACCAATAGAAATCGTTGTAGAAATTGAGCCAA
TAAAAAGTCTGGAAAGTCCAAGAGATCGGAAGA
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protein sequence of SMED30027474-orf-1

>SMED30027474-orf-1 ID=SMED30027474-orf-1|Name=SMED30027474-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=184bp
MSMILKGIRMGTFGARLLRNPQVFYPVRTQYLKYCCGTSEKVRLRAQTEM
QDYWEKNLKGPRPYSPHLLIYKMELPMTTSLLHRGTGIAMAIAWGGLGVG
AFWYTGQYAELINYVSSLDLATPIIYSAKLIMCWPLIFHYTNGMRHLAYD
AARGFDIPTTMRTGYIAIAVSIVLATLFASVKL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0022900electron transport chain
GO:0006099tricarboxylic acid cycle
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR014314Succ_DH_cytb556
IPR034804SQR/QFR_C/D
IPR000701SuccDH_FuR_B_TM-su
IPR018495Succ_DH_cyt_bsu_CS
Vocabulary: molecular function
TermDefinition
GO:0016627oxidoreductase activity, acting on the CH-CH group of donors
GO:0009055electron carrier activity
GO:0000104succinate dehydrogenase activity
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
GO:0045281succinate dehydrogenase complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR014314Succinate dehydrogenase, cytochrome b556 subunitPIRSFPIRSF000178SDH_cyt_b560coord: 22..183
e-value: 1.3E-31
score: 107.1
IPR014314Succinate dehydrogenase, cytochrome b556 subunitTIGRFAMTIGR02970TIGR02970coord: 62..179
e-value: 1.7E-21
score: 74.6
IPR000701Succinate dehydrogenase/fumarate reductase type B, transmembrane subunitPFAMPF01127Sdh_cytcoord: 61..177
e-value: 2.1E-19
score: 69.7
IPR034804Fumarate reductase/succinate dehydrogenase, transmembrane subunitGENE3DG3DSA:1.20.1300.10coord: 43..182
e-value: 1.4E-37
score: 131.0
IPR034804Fumarate reductase/succinate dehydrogenase, transmembrane subunitSUPERFAMILYSSF81343Fumarate reductase respiratory complex transmembrane subunitscoord: 54..179
NoneNo IPR availablePANTHERPTHR10978SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNITcoord: 40..179
NoneNo IPR availablePANTHERPTHR10978:SF5SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIALcoord: 40..179
NoneNo IPR availableCDDcd03499SQR_TypeC_SdhCcoord: 62..179
e-value: 2.6804E-29
score: 102.613
NoneNo IPR availableTMHMMTMhelixcoord: 87..106
NoneNo IPR availableTMHMMTMhelixcoord: 164..181
NoneNo IPR availableTMHMMTMhelixcoord: 121..143
IPR018495Succinate dehydrogenase, cytochrome b subunit, conserved sitePROSITEPS01001SDH_CYT_2coord: 139..152