Troponin i
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30027460 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 22Note: Hover over icons to view figure legend
Homology
BLAST of Troponin i vs. Ensembl Human
Match: TNNI3 (troponin I3, cardiac type [Source:HGNC Symbol;Acc:HGNC:11947]) HSP 1 Score: 65.0846 bits (157), Expect = 1.726e-11 Identity = 41/127 (32.28%), Postives = 69/127 (54.33%), Query Frame = 2 Query: 779 LKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKL--ARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 L T PL + + + LC+QLH R+++++EE+YD E K+ +I +LT K+ D++GKF +P L++V + + A +G K+SL R LK + E +E G DWR+++ Sbjct: 76 LSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGAR-AKESLD-LRAHLKQVKKEDTEKENREVG-----DWRKNI 195
BLAST of Troponin i vs. Ensembl Human
Match: TNNI3 (troponin I3, cardiac type [Source:HGNC Symbol;Acc:HGNC:11947]) HSP 1 Score: 62.7734 bits (151), Expect = 6.074e-11 Identity = 41/127 (32.28%), Postives = 69/127 (54.33%), Query Frame = 2 Query: 779 LKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKL--ARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 L T PL + + + LC+QLH R+++++EE+YD E K+ +I +LT K+ D++GKF +P L++V + + A +G K+SL R LK + E +E G DWR+++ Sbjct: 51 LSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLG-ARAKESLD-LRAHLKQVKKEDTEKENREVG-----DWRKNI 170
BLAST of Troponin i vs. Ensembl Human
Match: TNNI3 (troponin I3, cardiac type [Source:HGNC Symbol;Acc:HGNC:11947]) HSP 1 Score: 61.2326 bits (147), Expect = 3.913e-10 Identity = 42/138 (30.43%), Postives = 70/138 (50.72%), Query Frame = 2 Query: 779 LKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKI-----------RNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKL--ARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 L T PL + + + LC+QLH R+++++EE+YD E K+ + F I +LT K+ D++GKF +P L++V + + A +G K+SL R LK + E +E G DWR+++ Sbjct: 76 LSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEVGRMGSSGTFGIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLG-ARAKESLD-LRAHLKQVKKEDTEKENREVG-----DWRKNI 206
BLAST of Troponin i vs. Ensembl Human
Match: TNNI2 (troponin I2, fast skeletal type [Source:HGNC Symbol;Acc:HGNC:11946]) HSP 1 Score: 56.6102 bits (135), Expect = 7.980e-9 Identity = 39/127 (30.71%), Postives = 65/127 (51.18%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 N L PL+I + + LCKQLH +I+ EEEKYD EV+++ ++ ++ K+ D++GKF +P L++V + + + + + R LK Q K EKE DWR+++ Sbjct: 43 NYLAEHCPPLHIPG-SMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLK---QVKKEDTEKERDLRDVGDWRKNI 165
BLAST of Troponin i vs. Ensembl Human
Match: TNNI2 (troponin I2, fast skeletal type [Source:HGNC Symbol;Acc:HGNC:11946]) HSP 1 Score: 56.6102 bits (135), Expect = 7.980e-9 Identity = 39/127 (30.71%), Postives = 65/127 (51.18%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 N L PL+I + + LCKQLH +I+ EEEKYD EV+++ ++ ++ K+ D++GKF +P L++V + + + + + R LK Q K EKE DWR+++ Sbjct: 43 NYLAEHCPPLHIPG-SMSEVQELCKQLHAKIDAAEEEKYDMEVRVQKTSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLK---QVKKEDTEKERDLRDVGDWRKNI 165
BLAST of Troponin i vs. Ensembl Celegans
Match: tni-4 (Troponin I 4 [Source:UniProtKB/Swiss-Prot;Acc:O44572]) HSP 1 Score: 88.9669 bits (219), Expect = 2.651e-20 Identity = 51/121 (42.15%), Postives = 76/121 (62.81%), Query Frame = 2 Query: 779 LKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDW 1141 L+ + PL D +E+ +A+ ++ ER+ LE E YD +R ++F+INELT+ VND++GKFVKP LKKV+KTE K ++ K E + FR QLK +N+FAL+E++ K W Sbjct: 75 LQERIIPLP-DLDNEDDLEAVYDEIRERLIDLESENYDVSYIVRQKDFEINELTIAVNDLRGKFVKPTLKKVSKTEGKFDKLKKKEATKV--DFRAQLKVVDKNEFALDEEDTEKKEKAAW 192
BLAST of Troponin i vs. Ensembl Celegans
Match: tni-4 (Troponin I 4 [Source:UniProtKB/Swiss-Prot;Acc:O44572]) HSP 1 Score: 88.9669 bits (219), Expect = 2.651e-20 Identity = 51/121 (42.15%), Postives = 76/121 (62.81%), Query Frame = 2 Query: 779 LKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDW 1141 L+ + PL D +E+ +A+ ++ ER+ LE E YD +R ++F+INELT+ VND++GKFVKP LKKV+KTE K ++ K E + FR QLK +N+FAL+E++ K W Sbjct: 75 LQERIIPLP-DLDNEDDLEAVYDEIRERLIDLESENYDVSYIVRQKDFEINELTIAVNDLRGKFVKPTLKKVSKTEGKFDKLKKKEATKV--DFRAQLKVVDKNEFALDEEDTEKKEKAAW 192
BLAST of Troponin i vs. Ensembl Celegans
Match: unc-27 (Troponin I 2 [Source:UniProtKB/Swiss-Prot;Acc:Q9GYF1]) HSP 1 Score: 68.1662 bits (165), Expect = 1.084e-12 Identity = 40/99 (40.40%), Postives = 64/99 (64.65%), Query Frame = 2 Query: 782 KTVVGPLNIDSVDENS-CKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLK 1075 +T+ P N+DS+D+ + + L R+ +LEEEKYD + E +IN LT++VND++GKFVKP LKKV+K ++K + G+++ + + FR LK Sbjct: 79 RTISLP-NVDSIDDKGQLEKIYNDLWARLTQLEEEKYDINYVVSQTEAEINSLTIEVNDLRGKFVKPSLKKVSKYDNKFKKSGESKA-GTKEDFRANLK 175
BLAST of Troponin i vs. Ensembl Celegans
Match: tni-3 (Troponin I 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9XUN9]) HSP 1 Score: 66.6254 bits (161), Expect = 3.473e-12 Identity = 39/99 (39.39%), Postives = 63/99 (63.64%), Query Frame = 2 Query: 782 KTVVGPLNIDSV-DENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLK 1075 +T+ P ++DS+ D+ + + + R+ LEEEK+D + E +IN+LT++VND++GKFVKP LKKV+K ++K G+ +EK + FR LK Sbjct: 91 RTIPLP-DVDSINDQGQLLKIYEDMFARVCALEEEKFDINFGVSQTEAEINQLTIQVNDLRGKFVKPTLKKVSKYDNKFKSSGEVKEKSN---FRNNLK 185
BLAST of Troponin i vs. Ensembl Celegans
Match: tni-3 (Troponin I 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9XUN9]) HSP 1 Score: 66.6254 bits (161), Expect = 3.473e-12 Identity = 39/99 (39.39%), Postives = 63/99 (63.64%), Query Frame = 2 Query: 782 KTVVGPLNIDSV-DENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLK 1075 +T+ P ++DS+ D+ + + + R+ LEEEK+D + E +IN+LT++VND++GKFVKP LKKV+K ++K G+ +EK + FR LK Sbjct: 91 RTIPLP-DVDSINDQGQLLKIYEDMFARVCALEEEKFDINFGVSQTEAEINQLTIQVNDLRGKFVKPTLKKVSKYDNKFKSSGEVKEKSN---FRNNLK 185
BLAST of Troponin i vs. Ensembl Fly
Match: wupA (gene:FBgn0283471 transcript:FBtr0308237) HSP 1 Score: 85.1149 bits (209), Expect = 8.726e-19 Identity = 43/94 (45.74%), Postives = 66/94 (70.21%), Query Frame = 2 Query: 794 GPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLK 1075 P N+ E++ K+L KQ ++RIN+LE++KYD E ++ ++ +IN+L +VND++GKFVKP LKKV+K E+K A++ K K + FR QLK Sbjct: 80 SPRNLSDASEDTLKSLIKQHYDRINKLEDQKYDLEYVVKRKDVEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKLQK---KAAEFNFRNQLK 170
BLAST of Troponin i vs. Ensembl Fly
Match: wupA (gene:FBgn0283471 transcript:FBtr0336897) HSP 1 Score: 83.9593 bits (206), Expect = 1.256e-18 Identity = 43/94 (45.74%), Postives = 66/94 (70.21%), Query Frame = 2 Query: 794 GPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLK 1075 P N+ E++ K+L KQ ++RIN+LE++KYD E ++ ++ +IN+L +VND++GKFVKP LKKV+K E+K A++ K K + FR QLK Sbjct: 56 SPRNLSDASEDTLKSLIKQHYDRINKLEDQKYDLEYVVKRKDVEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKLQK---KAAEFNFRNQLK 146
BLAST of Troponin i vs. Ensembl Fly
Match: wupA (gene:FBgn0283471 transcript:FBtr0336896) HSP 1 Score: 83.9593 bits (206), Expect = 1.256e-18 Identity = 43/94 (45.74%), Postives = 66/94 (70.21%), Query Frame = 2 Query: 794 GPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLK 1075 P N+ E++ K+L KQ ++RIN+LE++KYD E ++ ++ +IN+L +VND++GKFVKP LKKV+K E+K A++ K K + FR QLK Sbjct: 56 SPRNLSDASEDTLKSLIKQHYDRINKLEDQKYDLEYVVKRKDVEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKLQK---KAAEFNFRNQLK 146
BLAST of Troponin i vs. Ensembl Fly
Match: wupA (gene:FBgn0283471 transcript:FBtr0336895) HSP 1 Score: 83.9593 bits (206), Expect = 1.256e-18 Identity = 43/94 (45.74%), Postives = 66/94 (70.21%), Query Frame = 2 Query: 794 GPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLK 1075 P N+ E++ K+L KQ ++RIN+LE++KYD E ++ ++ +IN+L +VND++GKFVKP LKKV+K E+K A++ K K + FR QLK Sbjct: 56 SPRNLSDASEDTLKSLIKQHYDRINKLEDQKYDLEYVVKRKDVEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKLQK---KAAEFNFRNQLK 146
BLAST of Troponin i vs. Ensembl Fly
Match: wupA (gene:FBgn0283471 transcript:FBtr0074520) HSP 1 Score: 84.7297 bits (208), Expect = 1.260e-18 Identity = 43/94 (45.74%), Postives = 66/94 (70.21%), Query Frame = 2 Query: 794 GPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLK 1075 P N+ E++ K+L KQ ++RIN+LE++KYD E ++ ++ +IN+L +VND++GKFVKP LKKV+K E+K A++ K K + FR QLK Sbjct: 80 SPRNLSDASEDTLKSLIKQHYDRINKLEDQKYDLEYVVKRKDVEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKLQK---KAAEFNFRNQLK 170
BLAST of Troponin i vs. Ensembl Zebrafish
Match: tnni1d (troponin I, skeletal, slow d [Source:ZFIN;Acc:ZDB-GENE-040718-374]) HSP 1 Score: 69.707 bits (169), Expect = 2.039e-13 Identity = 35/95 (36.84%), Postives = 55/95 (57.89%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKST 1081 PL + + + LCKQL+ +I+ ++EE+YD+E K++ DINEL +KV D+ GKF KP L+KV + ++ R + + R LKS Sbjct: 62 PLQLSGLSLEELQNLCKQLYSKIDTVDEERYDYEDKVKKHNKDINELKLKVQDLGGKFKKPALRKVRVSADEMMRALLGSKHKGSMDLRANLKSV 156
BLAST of Troponin i vs. Ensembl Zebrafish
Match: tnni1d (troponin I, skeletal, slow d [Source:ZFIN;Acc:ZDB-GENE-040718-374]) HSP 1 Score: 69.707 bits (169), Expect = 2.039e-13 Identity = 35/95 (36.84%), Postives = 55/95 (57.89%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKST 1081 PL + + + LCKQL+ +I+ ++EE+YD+E K++ DINEL +KV D+ GKF KP L+KV + ++ R + + R LKS Sbjct: 62 PLQLSGLSLEELQNLCKQLYSKIDTVDEERYDYEDKVKKHNKDINELKLKVQDLGGKFKKPALRKVRVSADEMMRALLGSKHKGSMDLRANLKSV 156
BLAST of Troponin i vs. Ensembl Zebrafish
Match: tnni1d (troponin I, skeletal, slow d [Source:ZFIN;Acc:ZDB-GENE-040718-374]) HSP 1 Score: 69.707 bits (169), Expect = 2.244e-13 Identity = 35/95 (36.84%), Postives = 55/95 (57.89%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKST 1081 PL + + + LCKQL+ +I+ ++EE+YD+E K++ DINEL +KV D+ GKF KP L+KV + ++ R + + R LKS Sbjct: 62 PLQLSGLSLEELQNLCKQLYSKIDTVDEERYDYEDKVKKHNKDINELKLKVQDLGGKFKKPALRKVRVSADEMMRALLGSKHKGSMDLRANLKSV 156
BLAST of Troponin i vs. Ensembl Zebrafish
Match: tnni1d (troponin I, skeletal, slow d [Source:ZFIN;Acc:ZDB-GENE-040718-374]) HSP 1 Score: 69.707 bits (169), Expect = 2.244e-13 Identity = 35/95 (36.84%), Postives = 55/95 (57.89%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKST 1081 PL + + + LCKQL+ +I+ ++EE+YD+E K++ DINEL +KV D+ GKF KP L+KV + ++ R + + R LKS Sbjct: 62 PLQLSGLSLEELQNLCKQLYSKIDTVDEERYDYEDKVKKHNKDINELKLKVQDLGGKFKKPALRKVRVSADEMMRALLGSKHKGSMDLRANLKSV 156
BLAST of Troponin i vs. Ensembl Zebrafish
Match: tnni1c (troponin I, skeletal, slow c [Source:ZFIN;Acc:ZDB-GENE-060825-192]) HSP 1 Score: 69.707 bits (169), Expect = 2.308e-13 Identity = 35/95 (36.84%), Postives = 54/95 (56.84%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKST 1081 PL I + + LC+QLH +I+ ++EE+YD+E K+ DI+EL +KV D+ GKF KP L+KV + ++ R + + R LKS Sbjct: 63 PLQITGLQLEELQKLCRQLHAKIDSVDEERYDFEAKVVKNNKDIHELKLKVQDLGGKFKKPALRKVRVSADEMMRALLGSKHKGSMDLRANLKSV 157
BLAST of Troponin i vs. Ensembl Xenopus
Match: thbs1 (thrombospondin 1 [Source:Xenbase;Acc:XB-GENE-486189]) HSP 1 Score: 64.6994 bits (156), Expect = 1.220e-11 Identity = 42/122 (34.43%), Postives = 70/122 (57.38%), Query Frame = 2 Query: 791 VGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVN-KTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 V L I + + LC +LH++I+ ++EE+YD EVK++ + +I LT K+ D+KGKF +P LK+V ++ L + N K S+ R LKS + E+++E TDWR+++ Sbjct: 51 VPSLQIAGLSLQQLQELCTKLHKQIDSVDEERYDIEVKVKKHDIEIEGLTQKIFDLKGKFKRPNLKRVRISADAMLKALLGNTHKVSVD-LRANLKSVRK-----EDEKEKTVEVTDWRKNI 166
BLAST of Troponin i vs. Ensembl Xenopus
Match: thbs1 (thrombospondin 1 [Source:Xenbase;Acc:XB-GENE-486189]) HSP 1 Score: 63.929 bits (154), Expect = 3.118e-11 Identity = 42/122 (34.43%), Postives = 70/122 (57.38%), Query Frame = 2 Query: 791 VGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVN-KTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 V L I + + LC +LH++I+ ++EE+YD EVK++ + +I LT K+ D+KGKF +P LK+V ++ L + N K S+ R LKS + E+++E TDWR+++ Sbjct: 65 VPSLQIAGLSLQQLQELCTKLHKQIDSVDEERYDIEVKVKKHDIEIEGLTQKIFDLKGKFKRPNLKRVRISADAMLKALLGNTHKVSVD-LRANLKSVRK-----EDEKEKTVEVTDWRKNI 180
BLAST of Troponin i vs. Ensembl Xenopus
Match: tmem256 (transmembrane protein 256 [Source:Xenbase;Acc:XB-GENE-5915594]) HSP 1 Score: 61.2326 bits (147), Expect = 4.592e-10 Identity = 31/99 (31.31%), Postives = 54/99 (54.55%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNK 1093 PL + + + + LC++LH RI+ ++EE+YD E K+ +I +L +K+ D++GKF KP L++V + + R + + R LK Q K Sbjct: 108 PLQLSGLSLSELQDLCRELHARIDVVDEERYDMEAKVNKNISEIEDLNLKIFDLRGKFKKPNLRRVRLSADAMMRALLGTKHKVSMDLRANLKQVKQTK 206
BLAST of Troponin i vs. Ensembl Xenopus
Match: ENSXETT00000035132.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:2:77037725:77045127:-1 gene:ENSXETG00000011405.1 transcript:ENSXETT00000035132.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 58.151 bits (139), Expect = 1.240e-9 Identity = 29/93 (31.18%), Postives = 52/93 (55.91%), Query Frame = 2 Query: 803 NIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKST 1081 N + + + LC+ LHE++ ++EE+YD EVK+ + +I +L +KV D++GKF +P L++V + + R + + R LKS Sbjct: 53 NYHGLSLAALQELCRDLHEKVGIVDEERYDIEVKVNHNTREIQDLRMKVLDLRGKFKRPALRRVRVSADAMLRALLGSKHKVSMDLRANLKSV 145
BLAST of Troponin i vs. Ensembl Xenopus
Match: cyb561 (cytochrome b561 [Source:Xenbase;Acc:XB-GENE-955821]) HSP 1 Score: 53.1434 bits (126), Expect = 1.487e-7 Identity = 25/75 (33.33%), Postives = 48/75 (64.00%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLAR 1021 PL++ S + + + CK++H +I+ ++EE+YD EVK+ ++ +L K+ D++GKF +P LK+V + + R Sbjct: 57 PLSLPS-NLSELQDFCKKMHAKIDVVDEERYDMEVKVGKSTKELEDLNQKIFDLRGKFKRPALKRVRMSADAMLR 130
BLAST of Troponin i vs. Ensembl Mouse
Match: Tnni3 (troponin I, cardiac 3 [Source:MGI Symbol;Acc:MGI:98783]) HSP 1 Score: 69.707 bits (169), Expect = 2.950e-13 Identity = 40/126 (31.75%), Postives = 70/126 (55.56%), Query Frame = 2 Query: 779 LKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVN-KTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 L+T PL +D + + LC+QLH R+++++EE+YD E K+ +I +LT K+ D++GKF +P L++V ++ + + K+SL R LK + E +E G DWR+++ Sbjct: 77 LRTRCQPLELDGLGFEELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQALLGTRAKESLD-LRAHLKQVKKEDIEKENREVG-----DWRKNI 196
BLAST of Troponin i vs. Ensembl Mouse
Match: Tnni2 (troponin I, skeletal, fast 2 [Source:MGI Symbol;Acc:MGI:105070]) HSP 1 Score: 57.3806 bits (137), Expect = 2.832e-9 Identity = 38/127 (29.92%), Postives = 64/127 (50.39%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 N L PL+I + + LCKQLH +I+ EEEKYD EVK++ ++ ++ K+ D++GKF +P L++V + + + + + R LK + EKE DWR+++ Sbjct: 33 NYLSEHCPPLHIPG-SMSEVQELCKQLHAKIDVAEEEKYDMEVKVQKSSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLKQVKKED---TEKERDLRDVGDWRKNI 155
BLAST of Troponin i vs. Ensembl Mouse
Match: Tnni2 (troponin I, skeletal, fast 2 [Source:MGI Symbol;Acc:MGI:105070]) HSP 1 Score: 57.3806 bits (137), Expect = 3.010e-9 Identity = 40/127 (31.50%), Postives = 65/127 (51.18%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 N L PL+I + + LCKQLH +I+ EEEKYD EVK++ ++ ++ K+ D++GKF +P L++V + + + + + R LK Q K EKE DWR+++ Sbjct: 43 NYLSEHCPPLHIPG-SMSEVQELCKQLHAKIDVAEEEKYDMEVKVQKSSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLK---QVKKEDTEKERDLRDVGDWRKNI 165
BLAST of Troponin i vs. Ensembl Mouse
Match: Tnni2 (troponin I, skeletal, fast 2 [Source:MGI Symbol;Acc:MGI:105070]) HSP 1 Score: 57.3806 bits (137), Expect = 3.010e-9 Identity = 40/127 (31.50%), Postives = 65/127 (51.18%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 N L PL+I + + LCKQLH +I+ EEEKYD EVK++ ++ ++ K+ D++GKF +P L++V + + + + + R LK Q K EKE DWR+++ Sbjct: 43 NYLSEHCPPLHIPG-SMSEVQELCKQLHAKIDVAEEEKYDMEVKVQKSSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLK---QVKKEDTEKERDLRDVGDWRKNI 165
BLAST of Troponin i vs. Ensembl Mouse
Match: Tnni2 (troponin I, skeletal, fast 2 [Source:MGI Symbol;Acc:MGI:105070]) HSP 1 Score: 55.8398 bits (133), Expect = 1.319e-8 Identity = 35/105 (33.33%), Postives = 57/105 (54.29%), Query Frame = 2 Query: 839 LCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 LCKQLH +I+ EEEKYD EVK++ ++ ++ K+ D++GKF +P L++V + + + + + R LK Q K EKE DWR+++ Sbjct: 72 LCKQLHAKIDVAEEEKYDMEVKVQKSSKELEDMNQKLFDLRGKFKRPPLRRVRMSADAMLKALLGSKHKVCMDLRANLK---QVKKEDTEKERDLRDVGDWRKNI 173
BLAST of Troponin i vs. UniProt/SwissProt
Match: sp|Q7M3Y3|TNNI_CHLNI (Troponin I OS=Chlamys nipponensis akazara OX=6571 PE=1 SV=2) HSP 1 Score: 113.62 bits (283), Expect = 3.935e-27 Identity = 61/113 (53.98%), Postives = 80/113 (70.80%), Query Frame = 2 Query: 788 VVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHG 1126 +V + D D + +ALCK H+R+ LEE+ YDWE KIR Q+F+INELT+KVND KGKFVKPVL+KVNKTESKL +I + E K+S FR LKS+ +++ +KE G G Sbjct: 182 LVPKFSTDGKDVAALQALCKDFHKRLASLEEDVYDWEAKIRKQDFEINELTLKVNDTKGKFVKPVLRKVNKTESKLDKIQRKEAKKS--DFRDNLKSSREHE---ADKEGGEG 289
BLAST of Troponin i vs. UniProt/SwissProt
Match: sp|O44572|TNNI4_CAEEL (Troponin I 4 OS=Caenorhabditis elegans OX=6239 GN=tni-4 PE=2 SV=2) HSP 1 Score: 88.9669 bits (219), Expect = 3.372e-19 Identity = 51/121 (42.15%), Postives = 76/121 (62.81%), Query Frame = 2 Query: 779 LKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDW 1141 L+ + PL D +E+ +A+ ++ ER+ LE E YD +R ++F+INELT+ VND++GKFVKP LKKV+KTE K ++ K E + FR QLK +N+FAL+E++ K W Sbjct: 75 LQERIIPLP-DLDNEDDLEAVYDEIRERLIDLESENYDVSYIVRQKDFEINELTIAVNDLRGKFVKPTLKKVSKTEGKFDKLKKKEATKV--DFRAQLKVVDKNEFALDEEDTEKKEKAAW 192
BLAST of Troponin i vs. UniProt/SwissProt
Match: sp|P05547|TNNI_ASTLP (Troponin I OS=Astacus leptodactylus OX=6717 PE=1 SV=1) HSP 1 Score: 83.5741 bits (205), Expect = 3.282e-17 Identity = 42/103 (40.78%), Postives = 70/103 (67.96%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALE 1105 P N+D +E +A+ K+ + ++E +KYD E++I ++++INEL ++VND++GKF+KP LKKV+K E+K A++ K K + FR QLK+ + +F LE Sbjct: 83 PKNLDGANEEQLRAIIKEYFDHTAQIESDKYDVELEIIRKDYEINELNIQVNDLRGKFIKPTLKKVSKYENKFAKLQK---KAAEFNFRNQLKTVKKKEFELE 182
BLAST of Troponin i vs. UniProt/SwissProt
Match: sp|P36188|TNNI_DROME (Troponin I OS=Drosophila melanogaster OX=7227 GN=wupA PE=2 SV=3) HSP 1 Score: 75.485 bits (184), Expect = 6.622e-14 Identity = 38/94 (40.43%), Postives = 62/94 (65.96%), Query Frame = 2 Query: 794 GPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLK 1075 P N+ E + +C++ +ER+ E +K+D E ++R ++++IN+L +VND++GKFVKP LKKV+K E+K A++ K K + FR QLK Sbjct: 141 SPRNLSDASEGELQEICEEYYERMYICEGQKWDLEYEVRKKDWEINDLNAQVNDLRGKFVKPALKKVSKYENKFAKLQK---KAAEFNFRNQLK 231
BLAST of Troponin i vs. UniProt/SwissProt
Match: sp|P48787|TNNI3_MOUSE (Troponin I, cardiac muscle OS=Mus musculus OX=10090 GN=Tnni3 PE=1 SV=2) HSP 1 Score: 69.707 bits (169), Expect = 2.064e-12 Identity = 40/126 (31.75%), Postives = 70/126 (55.56%), Query Frame = 2 Query: 779 LKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVN-KTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 L+T PL +D + + LC+QLH R+++++EE+YD E K+ +I +LT K+ D++GKF +P L++V ++ + + K+SL R LK + E +E G DWR+++ Sbjct: 77 LRTRCQPLELDGLGFEELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQALLGTRAKESLD-LRAHLKQVKKEDIEKENREVG-----DWRKNI 196
BLAST of Troponin i vs. TrEMBL
Match: A0A0X3NY02 (Troponin I OS=Schistocephalus solidus OX=70667 GN=TNNI PE=4 SV=1) HSP 1 Score: 154.066 bits (388), Expect = 5.258e-40 Identity = 80/128 (62.50%), Postives = 101/128 (78.91%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLK 1156 N L++ V PL++D +D+ + K+L+ER+ LE EKYDWEVKIR Q+F+INELT+KVND+KGKFVKPVLKKV+KTE+ +AR K E QSL +FR QLKSTGQNKFALEEK+EG K +WR+ LK Sbjct: 106 NYLRSKVQPLSLDGLDDAAVIKKIKELYERMKALEGEKYDWEVKIRRQDFEINELTIKVNDVKGKFVKPVLKKVSKTEN-MARFEKKES-QSLASFRSQLKSTGQNKFALEEKDEG-AHKPEWRDQLK 230
BLAST of Troponin i vs. TrEMBL
Match: A0A0X3PN01 (Troponin I OS=Schistocephalus solidus OX=70667 GN=TNNI PE=4 SV=1) HSP 1 Score: 154.066 bits (388), Expect = 7.058e-40 Identity = 80/128 (62.50%), Postives = 101/128 (78.91%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLK 1156 N L++ V PL++D +D+ + K+L+ER+ LE EKYDWEVKIR Q+F+INELT+KVND+KGKFVKPVLKKV+KTE+ +AR K E QSL +FR QLKSTGQNKFALEEK+EG K +WR+ LK Sbjct: 111 NYLRSKVQPLSLDGLDDAAVIKKIKELYERMKALEGEKYDWEVKIRRQDFEINELTIKVNDVKGKFVKPVLKKVSKTEN-MARFEKKES-QSLASFRSQLKSTGQNKFALEEKDEG-AHKPEWRDQLK 235
BLAST of Troponin i vs. TrEMBL
Match: A0A0X3NPV5 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR146010 PE=4 SV=1) HSP 1 Score: 154.066 bits (388), Expect = 8.782e-40 Identity = 80/128 (62.50%), Postives = 101/128 (78.91%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLK 1156 N L++ V PL++D +D+ + K+L+ER+ LE EKYDWEVKIR Q+F+INELT+KVND+KGKFVKPVLKKV+KTE+ +AR K E QSL +FR QLKSTGQNKFALEEK+EG K +WR+ LK Sbjct: 119 NYLRSKVQPLSLDGLDDAAVIKKIKELYERMKALEGEKYDWEVKIRRQDFEINELTIKVNDVKGKFVKPVLKKVSKTEN-MARFEKKES-QSLASFRSQLKSTGQNKFALEEKDEG-AHKPEWRDQLK 243
BLAST of Troponin i vs. TrEMBL
Match: A0A158R9I4 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS7318 PE=4 SV=1) HSP 1 Score: 151.369 bits (381), Expect = 1.662e-39 Identity = 77/128 (60.16%), Postives = 100/128 (78.12%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLK 1156 N L++ V PL +D +D+ + ++LH R+ +LE EKYDWEVK+R Q+ +INELT+KVND+KGKFVKPVLKKV+KTES+LARI K E ++L +FR QLKSTGQNKFALEEK+E K D+R+ LK Sbjct: 67 NYLRSRVQPLQLDGLDDAALAKKVRELHARVAQLEGEKYDWEVKLRRQDIEINELTMKVNDVKGKFVKPVLKKVSKTESQLARIEKKE--KTLASFRTQLKSTGQNKFALEEKDEAQ-HKVDFRDQLK 191
BLAST of Troponin i vs. TrEMBL
Match: A0A068X0C0 (Troponin i OS=Echinococcus granulosus OX=6210 GN=EgrG_000734700 PE=4 SV=1) HSP 1 Score: 152.525 bits (384), Expect = 2.199e-39 Identity = 77/128 (60.16%), Postives = 101/128 (78.91%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLK 1156 N L++ V PL +D +D+++ ++LH R+ +LE EKYDWEVK+R Q+ +INELT+KVND+KGKFVKPVLKKV+KTES+LARI K E ++L +FR QLKSTGQNKFALEEK+E K D+R+ LK Sbjct: 113 NYLRSRVQPLQLDGLDDSALAKKVRELHARVAQLEGEKYDWEVKLRRQDIEINELTMKVNDVKGKFVKPVLKKVSKTESQLARIEKKE--KTLASFRTQLKSTGQNKFALEEKDEA-SHKVDFRDQLK 237
BLAST of Troponin i vs. Ensembl Cavefish
Match: tnni1c (troponin I, skeletal, slow c [Source:ZFIN;Acc:ZDB-GENE-060825-192]) HSP 1 Score: 67.781 bits (164), Expect = 1.257e-12 Identity = 33/95 (34.74%), Postives = 55/95 (57.89%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKST 1081 PL + + + + LCKQLH +++ ++EE+YD+E K+ +I+EL +KV D+ GKF KP L+KV + ++ R + + R LKS Sbjct: 80 PLQLSGLAMDELQKLCKQLHAKVDAVDEERYDFEAKVVKNNKEIHELKLKVQDLGGKFKKPALRKVRVSADEMMRALLGSKHKGSMDLRANLKSV 174
BLAST of Troponin i vs. Ensembl Cavefish
Match: tnni1d (troponin I, skeletal, slow d [Source:ZFIN;Acc:ZDB-GENE-040718-374]) HSP 1 Score: 66.2402 bits (160), Expect = 2.197e-12 Identity = 39/119 (32.77%), Postives = 65/119 (54.62%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 PL + + + LC++L+E+I+ ++EE+YD E K+ DI+EL +KV D+ GKF KP L+KV + ++ R + + R LKS + K+E G DWR+++ Sbjct: 52 PLQLAGLSLADLQNLCRELYEKIDVVDEERYDCENKVIKHNKDIHELKLKVQDLGGKFKKPALRKVRVSADEMMRALLGSKHKGSMDLRANLKSVKKEDI----KQEKVGEVGDWRKNV 166
BLAST of Troponin i vs. Ensembl Cavefish
Match: tnni2a.3 (troponin I type 2a (skeletal, fast), tandem duplicate 3 [Source:ZFIN;Acc:ZDB-GENE-040718-80]) HSP 1 Score: 61.6178 bits (148), Expect = 6.601e-11 Identity = 41/107 (38.32%), Postives = 64/107 (59.81%), Query Frame = 2 Query: 839 LCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKL--ARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 LCK+LH I++++EE+YD E K+ + +I +L +KV D+KGKF KP L+KV + ++ A +G ++ K SL R LK + E KEE DWR+++ Sbjct: 55 LCKKLHSNIDKVDEERYDLEAKVAKSDKEIEDLKIKVIDLKGKFKKPALRKVRMSADQMLQALLG-SKHKVSLD-LRANLKQVKK-----EVKEEAADV-GDWRKNI 153
BLAST of Troponin i vs. Ensembl Cavefish
Match: tnni2b.1 (troponin I, fast skeletal muscle-like [Source:NCBI gene;Acc:103022042]) HSP 1 Score: 61.2326 bits (147), Expect = 1.241e-10 Identity = 27/55 (49.09%), Postives = 41/55 (74.55%), Query Frame = 2 Query: 839 LCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKT 1003 LCK+LH++I+ ++E++YD E K+ +I+EL +KV D+KGKF KP LKKV + Sbjct: 60 LCKKLHQQIDLVDEQRYDMESKVAKSNKEIDELKIKVQDLKGKFKKPALKKVRMS 114
BLAST of Troponin i vs. Ensembl Cavefish
Match: tnni1b (troponin I type 1b (skeletal, slow) [Source:ZFIN;Acc:ZDB-GENE-041212-37]) HSP 1 Score: 60.4622 bits (145), Expect = 1.686e-10 Identity = 37/120 (30.83%), Postives = 70/120 (58.33%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLAR-IGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 PL S+ + LC++LH +I+ ++EE+YD E K+++ +I +L +KV D++GKF +P L++V + + R + ++ K SL R LKS + + ++E +DWR+++ Sbjct: 35 PLQTSSMSFAELQELCRELHAKIDEVDEERYDIEAKVQHNTREIKDLNIKVLDLRGKFKRPNLRRVRVSADAILRSLLGSKHKVSLD-LRANLKSVKKE----DTEKEKSVEVSDWRKNV 149
BLAST of Troponin i vs. Ensembl Sea Lamprey
Match: tnni1a (troponin I type 1a (skeletal, slow) [Source:ZFIN;Acc:ZDB-GENE-030616-266]) HSP 1 Score: 59.3066 bits (142), Expect = 8.092e-11 Identity = 32/118 (27.12%), Postives = 64/118 (54.24%), Query Frame = 2 Query: 791 VGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWR 1144 V L + + + LC++LH+ I++++EE+YD +V++ + +I EL +K+ D++GKF +P L++V + + R + R LKS ++ +++E+ DWR Sbjct: 29 VIRLELSHLSSQELQDLCRELHKTIDKVDEERYDMQVRVEKNDKEIKELQMKIYDLRGKFKRPPLRRVRMSADAMLRALLGSRHKVSMDLRANLKSVKKD----DKEEKVRKEVGDWR 142
BLAST of Troponin i vs. Ensembl Sea Lamprey
Match: tnni4a (troponin I4a [Source:ZFIN;Acc:ZDB-GENE-041010-75]) HSP 1 Score: 50.0618 bits (118), Expect = 9.591e-8 Identity = 29/103 (28.16%), Postives = 51/103 (49.51%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKST 1081 N L V PL + + H++++ ++EE+YD E K++ + +I +L K+ D+KGKF +P LK+V + + R + + R LKS Sbjct: 50 NVLTERVPPLQLSGFTLQQLQNSAGSCHQKVDVVDEERYDIEYKVKKSQAEITDLNQKIFDLKGKFKRPNLKRVRMSADAMLRALLGSKHKVSMDLRANLKSV 152
BLAST of Troponin i vs. Ensembl Medaka
Match: ENSORLT00000027969.1 (troponin I, slow skeletal muscle [Source:NCBI gene;Acc:101167333]) HSP 1 Score: 68.9366 bits (167), Expect = 1.934e-13 Identity = 36/97 (37.11%), Postives = 56/97 (57.73%), Query Frame = 2 Query: 791 VGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKST 1081 + PL + + + + LCKQLHE+I+ ++EE+YD E K+ DI+EL +KV D+ GKF KP L+KV + ++ R + + R LKS Sbjct: 51 LPPLQLSGLSLDELQKLCKQLHEKIDVVDEERYDCEHKVVKHNKDIHELKLKVQDLGGKFKKPALRKVRVSADEMMRALLGSKHKGSMDLRANLKSV 147
BLAST of Troponin i vs. Ensembl Medaka
Match: tnni1a (troponin I type 1a (skeletal, slow) [Source:ZFIN;Acc:ZDB-GENE-030616-266]) HSP 1 Score: 62.3882 bits (150), Expect = 3.037e-11 Identity = 31/95 (32.63%), Postives = 55/95 (57.89%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKST 1081 PLN++ + +ALC++LH +I+ ++EE+YD E K+ +I +L +KV D++GKF +P L++V + + R + + R LKS Sbjct: 30 PLNMNGLSLAQLQALCRELHAKIDVVDEERYDIEAKVMLNTREIKDLNIKVLDLRGKFKRPNLRRVRVSADAILRSLLGSKHKVSMDLRANLKSV 124
BLAST of Troponin i vs. Ensembl Medaka
Match: tnni1b (troponin I, slow skeletal muscle [Source:NCBI gene;Acc:101156569]) HSP 1 Score: 60.077 bits (144), Expect = 2.628e-10 Identity = 36/123 (29.27%), Postives = 66/123 (53.66%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKT----DWREHL 1153 P+ + + +ALC++LH +I+ ++EE+YD E K+ + +I +L +KV D++GKF +P L++V + + R + + R LKS +KE+ KT DWR+++ Sbjct: 35 PVQTSGLSLSELQALCEELHAKIDVVDEERYDIEAKVLHNTREIKDLNIKVQDLRGKFKRPNLRRVRVSADAILRSLLGSKHKVSMDLRANLKSV--------KKEDAEKEKTVEVSDWRKNV 149
BLAST of Troponin i vs. Ensembl Medaka
Match: tnni1b (troponin I, slow skeletal muscle [Source:NCBI gene;Acc:101156569]) HSP 1 Score: 59.6918 bits (143), Expect = 3.657e-10 Identity = 36/123 (29.27%), Postives = 66/123 (53.66%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKT----DWREHL 1153 P+ + + +ALC++LH +I+ ++EE+YD E K+ + +I +L +KV D++GKF +P L++V + + R + + R LKS +KE+ KT DWR+++ Sbjct: 50 PVQTSGLSLSELQALCEELHAKIDVVDEERYDIEAKVLHNTREIKDLNIKVQDLRGKFKRPNLRRVRVSADAILRSLLGSKHKVSMDLRANLKSV--------KKEDAEKEKTVEVSDWRKNV 164
BLAST of Troponin i vs. Ensembl Medaka
Match: tnni4a (troponin I, slow skeletal muscle [Source:NCBI gene;Acc:101172899]) HSP 1 Score: 56.9954 bits (136), Expect = 3.031e-9 Identity = 38/119 (31.93%), Postives = 65/119 (54.62%), Query Frame = 2 Query: 797 PLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHL 1153 PL + + + LCK+LH++I+ ++E +YD EVK+ E +I L K+ D+KG +P LK+V KT + + K F+ LK+ ++ E++EE TDWR+++ Sbjct: 51 PLKLSGLSIQELQELCKELHQKIDVVDETRYDIEVKVAKNENEIQSLRQKIVDLKG-IKRPSLKRVKKTTDDMLGAYTDASKLMKADFKANLKTVKKDD---EKREEV----TDWRKNV 161
BLAST of Troponin i vs. Planmine SMEST
Match: SMESG000002071.1 (SMESG000002071.1) HSP 1 Score: 277.33 bits (708), Expect = 1.793e-90 Identity = 148/148 (100.00%), Postives = 148/148 (100.00%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLKTXXXXXXXXXXXXQPVEAEA 1216 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLKTSKEGGEDEKEESQPVEAEA Sbjct: 143 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLKTSKEGGEDEKEESQPVEAEA 290 HSP 2 Score: 65.855 bits (159), Expect = 9.063e-12 Identity = 37/61 (60.66%), Postives = 37/61 (60.66%), Query Frame = 2 Query: 338 QDGEEGDRTENSEAPRRRRNYEEEDTSNLTNKEDNPDVVVNNYSENADTNDSDRQAAEQDD 520 QDGEEGDRT DNPDVVVNNYSENADTNDSDRQAAEQDD Sbjct: 22 QDGEEGDRT------------------------DNPDVVVNNYSENADTNDSDRQAAEQDD 58
BLAST of Troponin i vs. Planmine SMEST
Match: SMESG000002071.1 (SMESG000002071.1) HSP 1 Score: 278.1 bits (710), Expect = 2.041e-90 Identity = 148/148 (100.00%), Postives = 148/148 (100.00%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLKTXXXXXXXXXXXXQPVEAEA 1216 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLKTSKEGGEDEKEESQPVEAEA Sbjct: 167 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLKTSKEGGEDEKEESQPVEAEA 314 HSP 2 Score: 124.405 bits (311), Expect = 7.320e-32 Identity = 60/61 (98.36%), Postives = 61/61 (100.00%), Query Frame = 2 Query: 338 QDGEEGDRTENSEAPRRRRNYEEEDTSNLTNKEDNPDVVVNNYSENADTNDSDRQAAEQDD 520 QDGEEGDRTENS+APRRRRNYEEEDTSNLTNKEDNPDVVVNNYSENADTNDSDRQAAEQDD Sbjct: 22 QDGEEGDRTENSDAPRRRRNYEEEDTSNLTNKEDNPDVVVNNYSENADTNDSDRQAAEQDD 82
BLAST of Troponin i vs. Planmine SMEST
Match: SMESG000036684.1 (SMESG000036684.1) HSP 1 Score: 136.346 bits (342), Expect = 3.747e-36 Identity = 71/129 (55.04%), Postives = 96/129 (74.42%), Query Frame = 2 Query: 773 NKLKTVVGPLNIDSVDENSCKALCKQLHERINRLEEEKYDWEVKIRNQEFDINELTVKVNDIKGKFVKPVLKKVNKTESKLARIGKNEEKQSLQAFRGQLKSTGQNKFALEEKEEGHGAKTDWREHLKT 1159 N LKTVV L +D+ + K+ +E++ LE +KYDWE+K++N +F+INELT+KVN+ KGKFVKPVLK+V+KTE K +++ K + Q+ +FR QLKSTGQNKFALEEK+E H DWREHLK+ Sbjct: 170 NYLKTVVPNLELDTSSAEEITKIVKKYYEKLCALESDKYDWEIKLQNLDFEINELTLKVNNAKGKFVKPVLKRVSKTEGKWSKLEK-QRGQNQISFRDQLKSTGQNKFALEEKDETH-KNPDWREHLKS 296 The following BLAST results are available for this feature:
BLAST of Troponin i vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Troponin i vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Troponin i vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Troponin i vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Troponin i vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Troponin i vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Troponin i vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Troponin i vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Troponin i vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Troponin i vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Troponin i vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Troponin i vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of Troponin i vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Troponin i vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30027460 ID=SMED30027460|Name=Troponin i|organism=Schmidtea mediterranea sexual|type=transcript|length=1409bpback to top protein sequence of SMED30027460-orf-1 >SMED30027460-orf-1 ID=SMED30027460-orf-1|Name=SMED30027460-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=315bp MADDERRKEREARRRARMDKMQDGEEGDRTENSEAPRRRRNYEEEDTSNLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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