Neurogenic locus Notch protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30027457 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: NOTCH1 (notch receptor 1 [Source:HGNC Symbol;Acc:HGNC:7881]) HSP 1 Score: 191.045 bits (484), Expect = 3.261e-48 Identity = 236/973 (24.25%), Postives = 378/973 (38.85%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP----------CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL----------------KETRKEALINIKIPKTFNEKQLII---------KKTKSPSLCDNLC-----KASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLT---------KCSTQTKLYELDLVLMTTM----------QNFTKYKSE--------------------FLQKLSSSLRMVVTVFNVTEINFNF--ATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVN--ENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGI------NLGTPCEYFVKK-TTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C + PC NG ++CSC G +G CE NV+DC NP C N GTC+D+ ++C C F+G C+ + N CL+ C+ GT ++ F C+CR G G C VI K + C N G C + N CKC G+ G C+ C S C NGG C + SP C C G FTG C P + T + P FN I + P L + C + N +C QCN AC +DGGDC DPW+ C C F+DG C+ +CN+ CLFDG DC ++ + + C + + + CD+ CNS +C +DG DC + + + S+ L EL VL T + F Y E L ++ +SL + + ++ L ++ QCV QCF S ++ FL A G+ L++P+++ V + + +L + A + GVLL K + ++ + S + G L D N+ +G+ +T + R PD ++R+ + ++ A L ++ T +DA DV +V+ + S G E N E ++ I+ + GA++ Q + + LH + R+ A + + ++ ++ + + V + G+ N T + + TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N +++PLFLAA EG+ ++ K LL +F I MD P+ IA+E+ ++I L+ E
Sbjct: 1187 CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDC--NPPVDPVSRSPKCFNNGTCVDQVGG-YSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCES------VINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDART-----CGSLRCLNGGTC-ISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYYGREEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMDVRGSIVYLEIDNRQCVQASSQCFQSATDVAAFLGALASLGS-LNIPYKIEAVQSETVEPPPPAQLHFMYV---AAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASD--GALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLD------AADLRMSAMAPTPPQGEVDADCMDV----NVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADAN-----IQDNMGRTPLHAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANK---DMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRL---PRDIAQERMHHDIVRLLDE 2115 HSP 2 Score: 100.523 bits (249), Expect = 1.861e-20 Identity = 72/213 (33.80%), Postives = 102/213 (47.89%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
CS++PC +G + D + C C G G CE N++DC +PC + GTC+DK + + C C + G++C + C C NGGTCE NG F C+C G+ C + C P HG C N C CDPG++G CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDS-GTCLDKIDG-YECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGING-FTCRCPEGYHDPTCLSEVNECNSNPCV-------HGACRDSLN-GYKCDCDPGWSGTNCDINNNE-----CESNPCVNGGTCKDMTSGY-VCTCREGFSGPNCQTNINECASNPCLN 802 HSP 3 Score: 95.5153 bits (236), Expect = 6.032e-19 Identity = 69/220 (31.36%), Postives = 98/220 (44.55%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+++ C + PCVNG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ PC C NGG C E+ F C C G+ G+ C V C + P + C N HG C C GY+G C+ + C+ + C NGG C N + C+C F G C + E + N
Sbjct: 752 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHG--------GYRCHCQAGYSGRNCETDID-----DCRPNPCHNGGSCTDGIN-TAFCDCLPGFRGTFCEEDINECASDPCRN 956 HSP 4 Score: 89.7373 bits (221), Expect = 3.029e-17 Identity = 71/215 (33.02%), Postives = 98/215 (45.58%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C++ PCV+G C ++ + ++C C GW G C+ N N+C NPC NGGTC D S + C C F G CQ N C + C N GTC G ++C C + G C V C P C N GEC + F C C G+ G C+ V+I C C +G C+ G C C+ ++G+NC + + R N
Sbjct: 720 CNSNPCVHGACRDSLN-GYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKD-MTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAG-YKCNCLLPYTGATCEVVLAPCAPSP------CRNGGECRQSEDYESFSCVCPTGWQGQTCE------VDINECVLSPCRHGASCQNTHGGY-RCHCQAGYSGRNCETDIDDCRPNPCHN 918 HSP 5 Score: 86.6557 bits (213), Expect = 2.583e-16 Identity = 68/201 (33.83%), Postives = 95/201 (47.26%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC--IDKKN-SQFTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
C+NG EA + C C + G C++ N C+ PCKN GTC +D++ + + C+C F G LC +N CL C NGGTC+ L ++C+C G+ G+ C Q C P C N G+C + + C C P + G C + E G K C +GG C + GS C C+ TG NC P
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQD-PNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNP------CANGGQCLPF-EASYICHCPPSFHGPTCRQDVN---ECGQKPGLCRHGGTCHN-EVGSYRCVCRATHTGPNCERP 218 HSP 6 Score: 85.8853 bits (211), Expect = 4.742e-16 Identity = 67/209 (32.06%), Postives = 95/209 (45.45%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC--LNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
CS PC NG C D C+C G+ G+ CEEN++DC N CKNGG C+D N+ + C C ++ G C + + C + C+NGGTC + G + C C G+ GE C+ C C++ + +C+C G TG C + C S+ C G C NG IC C +TG C+ + E
Sbjct: 222 CSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNT-YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGG-YNCVCVNGWTGEDCSENIDDCASAACFHGATCHDR-------VASFYCECPHGRTGLLCH------LNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDE 415 HSP 7 Score: 81.2629 bits (199), Expect = 1.122e-14 Identity = 68/211 (32.23%), Postives = 93/211 (44.08%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLK 949
C++ PC +G C++ D + C+C G+ G C N+++C NPC NGGTC D N FTC C + C E NPC++ G C NG ++C C G+ G C + N C P C N G C +MT C C G++G C C S+ C N G C + D C C +TG C + L
Sbjct: 645 CASSPCDSGTCLDKID-GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGING-FTCRCPEGYHDPTCLSEVNECNSNPCVH------GACRDSLNG-YKCDCDPGWSGTNCDINNNECESNP------CVNGGTCK---DMTSGYVCTCREGFSGPNCQTNINE-----CASNPCLNQGTC-IDDVAGYKCNCLLPYTGATCEVVLA 831 HSP 8 Score: 81.2629 bits (199), Expect = 1.190e-14 Identity = 63/203 (31.03%), Postives = 88/203 (43.35%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFD----PEFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PC N D ++ CSC G+ G C + N C+ NPC+NGGTC +++ C C + G CQ +PC + C NGG C E + C C F G C C +K LC + G C + C C +TG C++ + C C NGG C+ + + C C FTG+NC
Sbjct: 63 CLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFE-ASYICHCPPSFHGPTCRQDVNEC----GQKPGLCRHGGTCHNEVG-SYRCVCRATHTGPNCERPY-----VPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNC 254 HSP 9 Score: 79.337 bits (194), Expect = 4.325e-14 Identity = 56/165 (33.94%), Postives = 72/165 (43.64%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLEN---GMFQCKCRYGFIGEFCAVQ-NIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C NGG C + N C C F+G CQ NPCL+ C+N GTC ++ + C C GF G C + AC P C N G CD+ C+C PG++G C + C S+ C NGG C + S IC C F G C + E
Sbjct: 31 CLNGGKC-EAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNP------CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADP------CASNPCANGGQCLPFE-ASYICHCPPSFHGPTCRQDVNE 181 HSP 10 Score: 66.2402 bits (160), Expect = 4.577e-10 Identity = 56/183 (30.60%), Postives = 77/183 (42.08%), Query Frame = 2
Query: 395 FRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
+RC C G CE C +PC+NGGTC + C C F G C+ + C NC+NGG C N + C+C + G++C C ++P C N G C + C C G+TG+ C + + C S CF+G C S CEC TG C +
Sbjct: 202 YRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVN-TYNCRCPPEWTGQYCTEDVDECQLMPNA----CQNGGTCHNT-HGGYNCVCVNGWTGEDCSENID-----DCASAACFHGATCHDR-VASFYCECPHGRTGLLCHL 372
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: NOTCH2 (notch receptor 2 [Source:HGNC Symbol;Acc:HGNC:7882]) HSP 1 Score: 154.836 bits (390), Expect = 4.969e-37 Identity = 134/441 (30.39%), Postives = 194/441 (43.99%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP-CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCD--------KKKELPV----------------EIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLC-DNLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSS--CKFHK-CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTVFNV 1537
C N+PC NG C++ + F+CSC G +G CEEN++DC + P C NGG C+D+ ++C C F G C+ + N CL+ C + G+ C L N + C CR F G C CP +P C N G C + NM C+C PG++G RC +K E V E GC S C +GG C P C+C F+G C + + P+ C C +G+CD+ CN+ AC +DGGDC +PW C + C N+ C+ CN V+CLFD +C +S CK+ K C++ +++ CD+ CNS +CG+DG DC + + L E LV++ M + LQ S LR + T+ +
Sbjct: 1191 CQNQPCQNGGTCIDLVN-HFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGG-YSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTND-YLCVCRSAFTGRHCETFVDVCPQMP------CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSPRDCESGCASSPCQHGGSCHP-QRQPPYYSCQCAPPFSGSRCEL-----------------------YTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANC--SSPLPCWDYINN-QCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPEN---------------LAEGTLVIVVLMP-----PEQLLQDARSFLRALGTLLHT 1575 HSP 2 Score: 109.383 bits (272), Expect = 3.303e-23 Identity = 115/427 (26.93%), Postives = 166/427 (38.88%), Query Frame = 2
Query: 170 ASCKACSFTCDIISSHNFIKIIFNHQFQSELIMIFAKGFPMNVFILGCLLVIVSSKL------CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ--FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECD-IYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP--ICECKGEFTGKNCTIPLKETR----KEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCH---------KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSF 1378
A C + +CDI +S ++ H Q + I A N C L S C++ PC +G F +RC C G++G CE V++C PC+NGGTCID N F C+C G LC+ ++ +C NGG C G + C+C GF GE C C P C++ G D I C C +TG C+ ++ C C NGG C V N IC C F+G C + + ++ + P+ F SP C++ C +S C + GG C P R+ + C P F G C ++C C++ ++ +CDE CNS C +DGGDC + N +
Sbjct: 1096 AYCDVPNVSCDIAASRR--GVLVEHLCQHSGVCINAG----NTHYCQCPLGYTGSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVN-HFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGG-YSCRCLPGFAGERCEGDINECLSNP------CSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDV-----CPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCF---------CPSPRDCESGCASS-------------PCQH-GGSCHPQRQ----------PPYYSCQCAPP-------FSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPW 1463 HSP 3 Score: 103.219 bits (256), Expect = 2.859e-21 Identity = 84/250 (33.60%), Postives = 118/250 (47.20%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICD 1087
C ++PC+N + C C G+ G CEE+++DC+ NPC+NGG+C+D N+ F+C C F G+ CQ + N CL+ C+NGGTC N + CKC+ GF G C I + C N G C N + C C G+TG C + C S C N G C V G+ C C +TGKNC + L+N+ K ++K K+ S C LC + + CD
Sbjct: 877 CISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGVNT-FSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNS-YTCKCQAGFDGVHCENN------INECTESSCFNGGTCVDGIN-SFSCLCPVGFTGSFCLHEINE-----CSSHPCLNEGTC-VDGLGTYRCSCPLGYTGKNC---------QTLVNLCSRSPCKNKGTCVQK-KAESQC--LCPSGWAGAYCD 1099 HSP 4 Score: 94.3597 bits (233), Expect = 1.270e-18 Identity = 67/235 (28.51%), Postives = 118/235 (50.21%), Query Frame = 2
Query: 2243 DEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D YQ +SL+ + GE +H+AAR + + ++A + ++ D GR PL +++AADA + Q+LI + +++ N TT LI A +L + M++ L++ + VN +D G+S +HW+A NN +E + D++DN++++PLFLAA EG+ ++ K LL +F I MD P+ +A ++ ++I L+ E
Sbjct: 1861 DLVYQGASLQA---QTDRTGEMALHLAARYSRADAAKRLLDAG--ADANAQDNMGRCPLHAAVAADA-QGVFQILIRNRVTDLDARMND-------------------GTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNN---VEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRL---PRDVARDRMHHDIVRLLDE 2064 HSP 5 Score: 91.2781 bits (225), Expect = 1.121e-17 Identity = 70/201 (34.83%), Postives = 96/201 (47.76%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PC++G C ++C C GW G CE + N+C+ NPC+NGGTC + N + C C F G CQ + C + C N GTC +G + C C + G+ C Q + P P C N C PN + C C PG+ G RC ++I C S C N G+C GS +CEC F+G +C
Sbjct: 724 CLSNPCIHGNCTGGLS-GYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNG-YRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISG-YTCHCVLPYTGKNC--QTVLAPCSPNP----CENAAVCKESPNFESYTCLCAPGWQGQRCT------IDIDECISKPCMNHGLCHNT-QGSYMCECPPGFSGMDC 908 HSP 6 Score: 90.1225 bits (222), Expect = 2.838e-17 Identity = 71/219 (32.42%), Postives = 99/219 (45.21%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
V C + PC NG + +RC+C G+KG C+ N+++C NPC N GTC D S +TC+C + G CQ PC CEN C+ N + C C G+ G+ C + C P C NHG C + C+C PG++G C++ + C ++ C NGG C N + C C FTG C + E E N
Sbjct: 756 VDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDI-SGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKP------CMNHGLCHNT-QGSYMCECPPGFSGMDCEEDID-----DCLANPCQNGGSCMDGVN-TFSCLCLPGFTGDKCQTDMNECLSEPCKN 960 HSP 7 Score: 88.5817 bits (218), Expect = 7.618e-17 Identity = 72/203 (35.47%), Postives = 100/203 (49.26%), Query Frame = 2
Query: 350 RPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKN-SQFTCNCTSQFIGNLCQF--ENPC-LNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDK---KKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
PCVN G CV + C C G+ GE C+ + C +N C+NGGTC+ + + TC C S F G CQ+ +PC ++ C NGGTC L ++C C+ GF G+ C + AC P C N C N CKC G+TG +C+ + ++P +C +GG C L GS C+C FTG+ C
Sbjct: 33 EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHR-DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTD-ACLSHP------CANGSTCTTVANQ-FSCKCLTGFTGQKCETDVNECDIP-------GHCQHGGTCLNLP-GSYQCQCPQGFTGQYC 218 HSP 8 Score: 88.1965 bits (217), Expect = 1.006e-16 Identity = 68/209 (32.54%), Postives = 97/209 (46.41%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCL--NVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
C+ PCVNG C + D F C+C G++G TCE N++DC + C+NGG C+D N+ + C C Q+ G C + + CL C+NGGTC + NG + C C G+ G+ C+ C C I + C C G G C ++ C S+ C G +C NG IC C + G +CT + E
Sbjct: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNT-YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCAN-RNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTC-------IDRVASFSCMCPEGKAGLLCH------LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDE 418 HSP 9 Score: 86.6557 bits (213), Expect = 3.066e-16 Identity = 65/193 (33.68%), Postives = 88/193 (45.60%), Query Frame = 2
Query: 365 GKCV-EAFDPEFRCSCWHGWKGETCEENV-NDC-IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
G CV +A + C C G+ GE C+ + + C + PC NGGTC + C C F G CQ+ + CL+ C NG TC ++ N F CKC GF G+ C C IP C + G C P + C+C G+TG CD + + C C NGG C+ + + C C F G C
Sbjct: 77 GTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVAN-QFSCKCLTGFTGQKCETDVNECD-IPGH----CQHGGTCLNLPG-SYQCQCPQGFTGQYCDS-----LYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC 257 HSP 10 Score: 86.2705 bits (212), Expect = 3.723e-16 Identity = 65/210 (30.95%), Postives = 95/210 (45.24%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDN-GSPICECKGEFTGKNCTIPLKETRKEALIN 976
C NG + + C C +GW G+ C EN++DC C G TCID+ S F+C C G LC ++ C++ C G C++ NG + C C G+ G C C + C + G+C + + C+C GY G RC+ ++I C SD C N C LD G C C F G +C + + E + +N
Sbjct: 309 CQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVAS-FSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAM---ANSNPCEHAGKC-VNTDGAFHCECLKGYAGPRCE------MDINECHSDPCQNDATC--LDKIGGFTCLCMPGFKGVHCELEINECQSNPCVN 505 HSP 11 Score: 85.1149 bits (209), Expect = 9.659e-16 Identity = 69/205 (33.66%), Postives = 92/205 (44.88%), Query Frame = 2
Query: 365 GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
GKCV D F C C G+ G CE ++N+C +PC+N TC+DK FTC C F G C+ E N C + C N G C N FQC C GF G C + C P C N +C +PN C+C G+TG C++ + C D C +G +D S C C + G C+ + E +N
Sbjct: 431 GKCVNT-DGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGG-FTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVN-RFQCLCPPGFTGPVCQIDIDDCSSTP------CLNGAKCIDHPN-GYECQCATGFTGVLCEENID-----NCDPDPCHHGQCQDGID--SYTCICNPGYMGAICSDQIDECYSSPCLN 618 HSP 12 Score: 82.0333 bits (201), Expect = 6.669e-15 Identity = 71/216 (32.87%), Postives = 103/216 (47.69%), Query Frame = 2
Query: 341 CSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDN-GSPICECKGEFTGKNCTIPLKETRKEALIN 976
C++ PC G C+ + FRC C G +C VN+C+ NPC +G S + C C + ++G C+ + N CL+ C+NGGTC++L NG ++C C+ GF G C V C P C N G C + +++ + C C YTG C V C + C N VCK N S C C + G+ CTI + E + +N
Sbjct: 686 CASNPCRKGATCINGVN-GFRCICPEGPHHPSCYSQVNECLSNPCIHGN--CTGGLSGYKCLCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNG-YRCTCKKGFKGYNCQVNIDECASNP------CLNQGTC--FDDISGYTCHCVLPYTGKNCQT-----VLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMN 884
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: NOTCH4 (notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]) HSP 1 Score: 138.272 bits (347), Expect = 2.679e-32 Identity = 107/386 (27.72%), Postives = 163/386 (42.23%), Query Frame = 2
Query: 407 CWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTL--FCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC--KVLDNGSPICECKGEFTGKNCTIPLKE----TRKEALINIKIPKTFNEKQLIIK----------KTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCH-KSSCKF---HKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNE-----GLTKCSTQTKLYELDLVLMTTMQ 1459
C G+ G+ C + ++ C PC N GTC K F C C F+G C+ + + CL+ C GT C SL N F C+C G G++C V+ C + C + G C+ L C C G+ G C + C +C +GG+C P C C + G +C P L N +T + + + P C+ +G CD C+ N+DGGDC DPW+ C + C +F DG C+P+C++ +CLFDG DC +C C + + N C++ CN+ +CG+DGGDC + + L+ + +L+ L VL T++
Sbjct: 1 CAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGG-FHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLAN-AFYCQCLPGHTGQWCEVEIDPC------HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAP-----SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGA--KGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSH--SRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLSLTLR 369 HSP 2 Score: 87.0409 bits (214), Expect = 1.707e-16 Identity = 86/324 (26.54%), Postives = 122/324 (37.65%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGT--CIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGM--FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC--DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP--ICECK---------------------------------GEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIK-----------KTKSPSLC----DNLCKASFENGICDQQCNTFACNYDGGDCDP 1138
C ++PC N G C F C+C G+ G CE +V++C+ PC GT C N+ F C C G C+ E +PC + C +GGTCE+ F C C GF G C+ + +C C++ G C P C C GY G C P G S +NG + G P C C G + G +C++ + + K + + F + Q + ++P C D C F NG C++ CNT C +DGGDC P
Sbjct: 17 CQSQPCHNHGTCTPKPG-GFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANA-FYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC------GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDC-LTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRP 331 HSP 3 Score: 75.0998 bits (183), Expect = 6.894e-13 Identity = 57/215 (26.51%), Postives = 103/215 (47.91%), Query Frame = 2
Query: 2297 NGESLMHIAARMNSGANIIKQINA-INPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLIQ 2938
GE+ +H+AAR + + + A NP+ D GRTPL +++AADA E QLL+ +Q +++ TT L+ A +L ++++ L+ + V D G++ +HW+A NN+ L + D +DN +++PLFLAA EGA++ + LL ++ D P +A ++ +++ L++
Sbjct: 678 TGETPLHLAARFSRPTAARRLLEAGANPNQP---DRAGRTPLHAAVAADAREVC-QLLLRSRQTAVDARTED-------------------GTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADK---DAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELR-DQAGLAPADVAHQRNHWDLLTLLE 865
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: NOTCH4 (notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]) HSP 1 Score: 137.887 bits (346), Expect = 6.315e-32 Identity = 115/408 (28.19%), Postives = 173/408 (42.40%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTL--FCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC--KVLDNGSPICECKGEFTGKNCTIPLKE----TRKEALINIKIPKTFNEKQLIIK----------KTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCH-KSSCKF---HKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNE-----GLTKCSTQTKLYELDLVLMTTMQ 1459
C +RPC NG A + C C G+ G+ C + ++ C PC N GTC K F C C F+G C+ + + CL+ C GT C SL N F C+C G G++C V+ C + C + G C+ L C C G+ G C + C +C +GG+C P C C + G +C P L N +T + + + P C+ +G CD C+ N+DGGDC DPW+ C + C +F DG C+P+C++ +CLFDG DC +C C + + N C++ CN+ +CG+DGGDC + + L+ + +L+ L VL T++
Sbjct: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGG-FHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLAN-AFYCQCLPGHTGQWCEVEIDPC------HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAP-----SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGA--KGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSH--SRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLSLTLR 1324 HSP 2 Score: 114.775 bits (286), Expect = 7.047e-25 Identity = 116/419 (27.68%), Postives = 163/419 (38.90%), Query Frame = 2
Query: 338 LCSNRPCV-NGKCVEAFDPEFRCSCWHGWKGETCEENVNDC----------IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKE--------------------------LPVEIG---------CKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCT---------------------IPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKS------SCKFH-KCSELYQNKICDEECNSPQCGFDGGDCHT 1360
LC+ +PC N C++ P F C C GW G C ++ C + + C NGG C+D S F C+C F G+LCQ NPC + C+NG TC + +G + C+C G+ G+ C+ + AC + + C+NHG C P C C PG+ G RC+ + LP G C S CF+GG C+ GSP IC C F G C+ P R L P SP L + C + G +C+ C + P +C K C+G DG C+ C+ +DG DC C H +C L+++ C +C+S +C FDG DC T
Sbjct: 847 LCAQKPCPRNSHCLQT-GPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF-CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDAC------QSQPCHNHGTCTPKPG-GFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEAT-AGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCS---CPHS----SPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCET 1247 HSP 3 Score: 88.5817 bits (218), Expect = 6.267e-17 Identity = 71/199 (35.68%), Postives = 89/199 (44.72%), Query Frame = 2
Query: 353 PCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL 946
PC +G F C C G+ G CE + N+C+ PC G TC+D + F C C G LC+ E N C + C N C L NG FQC C GF G C I + + C N G+C P CKC PG+ G RC + + C SD C G C L G+ C C FTG+ C +PL
Sbjct: 445 PCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLL-ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNG-FQCICLPGFSGTRCEED------IDECRSSPCANGGQCQDQPG-AFHCKCLPGFEGPRCQTEVDE-----CLSDPCPVGASCLDLP-GAFFCLCPSGFTGQLCEVPL 628 HSP 4 Score: 83.9593 bits (206), Expect = 1.704e-15 Identity = 53/150 (35.33%), Postives = 69/150 (46.00%), Query Frame = 2
Query: 467 PCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVN-CENGGTCESL-------------ENGMFQCKCRYGFIGEFCAVQ-NIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC 871
PC NGGTC+ Q TC C F+G CQF +PC N C+NGG+C++L F C C GF GE C + CP C+ G C I + C C PG+TG++C + C ++ C NGGVC
Sbjct: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPP------SFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF------CSANPCVNGGVC 171 HSP 5 Score: 82.8037 bits (203), Expect = 3.643e-15 Identity = 59/173 (34.10%), Postives = 77/173 (44.51%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC 871
C NG + F C C GW G +CEEN++DCI C G TCID+ S F+C C G LC E+ CL+ C C + G C C+ G+ G C C ++ ++ C + G C P + C C PGYTG RC+ C S C G C
Sbjct: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGS-FSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC-LMAQQGPSPCEHGGSCLNTPG-SFNCLCPPGYTGSRCEADHNE-----CLSQPCHPGSTC 490 HSP 6 Score: 77.0258 bits (188), Expect = 2.380e-13 Identity = 57/215 (26.51%), Postives = 103/215 (47.91%), Query Frame = 2
Query: 2297 NGESLMHIAARMNSGANIIKQINA-INPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLIQ 2938
GE+ +H+AAR + + + A NP+ D GRTPL +++AADA E QLL+ +Q +++ TT L+ A +L ++++ L+ + V D G++ +HW+A NN+ L + D +DN +++PLFLAA EGA++ + LL ++ D P +A ++ +++ L++
Sbjct: 1633 TGETPLHLAARFSRPTAARRLLEAGANPNQP---DRAGRTPLHAAVAADAREVC-QLLLRSRQTAVDARTED-------------------GTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADK---DAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELR-DQAGLAPADVAHQRNHWDLLTLLE 1820 HSP 7 Score: 73.559 bits (179), Expect = 2.945e-12 Identity = 68/205 (33.17%), Postives = 90/205 (43.90%), Query Frame = 2
Query: 338 LCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQN--PCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESL---ENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
CS PCVNG A P+ +C C G++G CE +VN+C Q+ PC G +C + S F C C G C+ PC C NGGTC+ + ++ C C GFIG C V C C N G C + T C C +TG C + + G +C NGG C+ GS C C + G +C
Sbjct: 159 FCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS-FQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC------VSHQCQNGGTCQDGLD-TYTCLCPETWTGWDCSEDVDECETQG--PPHCRNGGTCQN-SAGSFHCVCVSGWGGTSC 352 HSP 8 Score: 73.1738 bits (178), Expect = 3.924e-12 Identity = 70/227 (30.84%), Postives = 100/227 (44.05%), Query Frame = 2
Query: 335 KLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVND-CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ------FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYP---NMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCK-VLDNGSPICECKGEFTGKNCTIPLKETRKEALINIK 982
CS R G+C +CSC GW GE C+ + D C NPC NGG C+ Q C+C F G+ C+ F++P C G +C + G FQC C G G C ++ CP P+ C+N G C + P + C C PG+ G C+ + C S C NGG C+ LD + C C +TG +C+ + E + + +
Sbjct: 125 SFCSKR----GRCHIQASGRPQCSCMPGWTGEQCQ--LRDFCSANPCVNGGVCL-ATYPQIQCHCPPGFEGHACERDVNECFQDP---GPCPKGTSCHNTL-GSFQCLCPVGQEGPRCELRAGPCP--PRG----CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----NCVSHQCQNGGTCQDGLDTYT--CLCPETWTGWDCSEDVDECETQGPPHCR 327 HSP 9 Score: 71.633 bits (174), Expect = 1.108e-11 Identity = 66/225 (29.33%), Postives = 87/225 (38.67%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIG----------NLCQFENPC------LNVNCENGG----------TCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PC NG + F C C G++G C+ V++C+ +PC G +C+D + F C C S F G NLCQ + C N C +G TC C C G+ G C + C P C + G C YP + + C C GYTG C ++ C S C NGG C G C C TG C
Sbjct: 555 CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA-FFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAP------CAHGGTC--YPQPSGYNCTCPTGYTGPTCSEEM-----TACHSGPCLNGGSCNPSPGGY-YCTCPPSHTGPQC 764 HSP 10 Score: 70.8626 bits (172), Expect = 1.620e-11 Identity = 64/255 (25.10%), Postives = 102/255 (40.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-------FENPCLN-VNCEN--------------GGTCESL-----------------ENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC+NG + C+C G C+ + + C+ PC NGGTC+++ + F+C C F G C+ ++PC N C++ GG+C++L F C C G+ G C + +C + LC+N G C + + FC C PG+ G C C+S C NG C +G +C+C + G+NC+ L + + N
Sbjct: 733 CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT-FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLC-VDSGPSYFCHCPPGFQGSLCQDHVNP-----CESRPCQNGATCMAQPSGY-LCQCAPGYDGQNCSKELDACQSQPCHN 979 HSP 11 Score: 65.0846 bits (157), Expect = 1.004e-9 Identity = 62/196 (31.63%), Postives = 81/196 (41.33%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCK--------VLDNGSPIC 901
C ++PC G F C C G +G+ CE N+C PC N C D N F C C F G C+ + + C + C NGG C+ + G F CKC GF G C + C P C C P FC C G+TG C E+P+ C + C +CK + +GSP C
Sbjct: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNG-FQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD-QPGAFHCKCLPGFEGPRCQTEVDECLSDP------CPVGASCLDLPG-AFFCLCPSGFTGQLC----EVPL---CAPNLCQPKQICKDQKDKANCLCPDGSPGC 658 HSP 12 Score: 59.3066 bits (142), Expect = 6.589e-8 Identity = 53/171 (30.99%), Postives = 69/171 (40.35%), Query Frame = 2
Query: 353 PCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP--CKNGGTC-------------IDKKNSQFTCNCTSQFIGNLCQ--FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDK 808
PC NG C+ + C C G+ GETC+ D QN C+NGG+C F C C F G CQ E+PC C G C +G QC C G+ GE C +++ C N G C YP + C C PG+ G C++
Sbjct: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQ--FPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-------SANPCVNGGVCLATYPQIQ--CHCPPGFEGHACER 193
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Match: NOTCH4 (notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]) HSP 1 Score: 137.502 bits (345), Expect = 7.293e-32 Identity = 115/408 (28.19%), Postives = 173/408 (42.40%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTL--FCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC--KVLDNGSPICECKGEFTGKNCTIPLKE----TRKEALINIKIPKTFNEKQLIIK----------KTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCH-KSSCKF---HKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNE-----GLTKCSTQTKLYELDLVLMTTMQ 1459
C +RPC NG A + C C G+ G+ C + ++ C PC N GTC K F C C F+G C+ + + CL+ C GT C SL N F C+C G G++C V+ C + C + G C+ L C C G+ G C + C +C +GG+C P C C + G +C P L N +T + + + P C+ +G CD C+ N+DGGDC DPW+ C + C +F DG C+P+C++ +CLFDG DC +C C + + N C++ CN+ +CG+DGGDC + + L+ + +L+ L VL T++
Sbjct: 933 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGG-FHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLAN-AFYCQCLPGHTGQWCEVEIDPC------HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAP-----SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGA--KGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSH--SRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLSLTLR 1323 HSP 2 Score: 114.775 bits (286), Expect = 7.799e-25 Identity = 116/419 (27.68%), Postives = 163/419 (38.90%), Query Frame = 2
Query: 338 LCSNRPCV-NGKCVEAFDPEFRCSCWHGWKGETCEENVNDC----------IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKE--------------------------LPVEIG---------CKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCT---------------------IPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKS------SCKFH-KCSELYQNKICDEECNSPQCGFDGGDCHT 1360
LC+ +PC N C++ P F C C GW G C ++ C + + C NGG C+D S F C+C F G+LCQ NPC + C+NG TC + +G + C+C G+ G+ C+ + AC + + C+NHG C P C C PG+ G RC+ + LP G C S CF+GG C+ GSP IC C F G C+ P R L P SP L + C + G +C+ C + P +C K C+G DG C+ C+ +DG DC C H +C L+++ C +C+S +C FDG DC T
Sbjct: 846 LCAQKPCPRNSHCLQT-GPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF-CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSG-YLCQCAPGYDGQNCSKELDAC------QSQPCHNHGTCTPKPG-GFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEAT-AGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCS---CPHS----SPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCET 1246 HSP 3 Score: 88.5817 bits (218), Expect = 6.994e-17 Identity = 71/199 (35.68%), Postives = 89/199 (44.72%), Query Frame = 2
Query: 353 PCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL 946
PC +G F C C G+ G CE + N+C+ PC G TC+D + F C C G LC+ E N C + C N C L NG FQC C GF G C I + + C N G+C P CKC PG+ G RC + + C SD C G C L G+ C C FTG+ C +PL
Sbjct: 444 PCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLL-ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNG-FQCICLPGFSGTRCEED------IDECRSSPCANGGQCQDQPG-AFHCKCLPGFEGPRCQTEVDE-----CLSDPCPVGASCLDLP-GAFFCLCPSGFTGQLCEVPL 627 HSP 4 Score: 85.5001 bits (210), Expect = 5.682e-16 Identity = 54/150 (36.00%), Postives = 69/150 (46.00%), Query Frame = 2
Query: 467 PCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVN-CENGGTCESL-------------ENGMFQCKCRYGFIGEFCAVQ-NIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC 871
PC NGGTC+ Q TC C F+G CQF +PC N C+NGG+C++L F C C GF GE C Q CP C+ G C I + C C PG+TG++C + C ++ C NGGVC
Sbjct: 33 PCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLEDPCPP------SFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDF------CSANPCVNGGVC 170 HSP 5 Score: 82.8037 bits (203), Expect = 3.930e-15 Identity = 59/173 (34.10%), Postives = 77/173 (44.51%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC 871
C NG + F C C GW G +CEEN++DCI C G TCID+ S F+C C G LC E+ CL+ C C + G C C+ G+ G C C ++ ++ C + G C P + C C PGYTG RC+ C S C G C
Sbjct: 325 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGS-FSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC-LMAQQGPSPCEHGGSCLNTPG-SFNCLCPPGYTGSRCEADHNE-----CLSQPCHPGSTC 489 HSP 6 Score: 77.0258 bits (188), Expect = 2.503e-13 Identity = 57/215 (26.51%), Postives = 103/215 (47.91%), Query Frame = 2
Query: 2297 NGESLMHIAARMNSGANIIKQINA-INPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLIQ 2938
GE+ +H+AAR + + + A NP+ D GRTPL +++AADA E QLL+ +Q +++ TT L+ A +L ++++ L+ + V D G++ +HW+A NN+ L + D +DN +++PLFLAA EGA++ + LL ++ D P +A ++ +++ L++
Sbjct: 1632 TGETPLHLAARFSRPTAARRLLEAGANPNQP---DRAGRTPLHAAVAADAREVC-QLLLRSRQTAVDARTED-------------------GTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADK---DAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELR-DQAGLAPADVAHQRNHWDLLTLLE 1819 HSP 7 Score: 73.1738 bits (178), Expect = 3.314e-12 Identity = 68/205 (33.17%), Postives = 90/205 (43.90%), Query Frame = 2
Query: 338 LCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQN--PCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESL---ENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
CS PCVNG A P+ +C C G++G CE +VN+C Q+ PC G +C + S F C C G C+ PC C NGGTC+ + ++ C C GFIG C V C C N G C + T C C +TG C + + G +C NGG C+ GS C C + G +C
Sbjct: 158 FCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS-FQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC------VSHQCQNGGTCQDGLD-TYTCLCPETWTGWDCSEDVDECETQG--PPHCRNGGTCQN-SAGSFHCVCVSGWGGTSC 351 HSP 8 Score: 72.7886 bits (177), Expect = 4.529e-12 Identity = 70/227 (30.84%), Postives = 100/227 (44.05%), Query Frame = 2
Query: 335 KLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVND-CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ------FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYP---NMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCK-VLDNGSPICECKGEFTGKNCTIPLKETRKEALINIK 982
CS R G+C +CSC GW GE C+ + D C NPC NGG C+ Q C+C F G+ C+ F++P C G +C + G FQC C G G C ++ CP P+ C+N G C + P + C C PG+ G C+ + C S C NGG C+ LD + C C +TG +C+ + E + + +
Sbjct: 124 SFCSKR----GRCHIQASGRPQCSCMPGWTGEQCQ--LRDFCSANPCVNGGVCL-ATYPQIQCHCPPGFEGHACERDVNECFQDP---GPCPKGTSCHNTL-GSFQCLCPVGQEGPRCELRAGPCP--PRG----CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD-----NCVSHQCQNGGTCQDGLDTYT--CLCPETWTGWDCSEDVDECETQGPPHCR 326 HSP 9 Score: 71.2478 bits (173), Expect = 1.236e-11 Identity = 66/225 (29.33%), Postives = 87/225 (38.67%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIG----------NLCQFENPC------LNVNCENGG----------TCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PC NG + F C C G++G C+ V++C+ +PC G +C+D + F C C S F G NLCQ + C N C +G TC C C G+ G C + C P C + G C YP + + C C GYTG C ++ C S C NGG C G C C TG C
Sbjct: 554 CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA-FFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAP------CAHGGTC--YPQPSGYNCTCPTGYTGPTCSEEM-----TACHSGPCLNGGSCNPSPGGY-YCTCPPSHTGPQC 763 HSP 10 Score: 70.8626 bits (172), Expect = 1.748e-11 Identity = 64/255 (25.10%), Postives = 102/255 (40.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-------FENPCLN-VNCEN--------------GGTCESL-----------------ENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC+NG + C+C G C+ + + C+ PC NGGTC+++ + F+C C F G C+ ++PC N C++ GG+C++L F C C G+ G C + +C + LC+N G C + + FC C PG+ G C C+S C NG C +G +C+C + G+NC+ L + + N
Sbjct: 732 CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT-FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLC-VDSGPSYFCHCPPGFQGSLCQDHVNP-----CESRPCQNGATCMAQPSGY-LCQCAPGYDGQNCSKELDACQSQPCHN 978 HSP 11 Score: 65.0846 bits (157), Expect = 1.101e-9 Identity = 62/196 (31.63%), Postives = 81/196 (41.33%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCK--------VLDNGSPIC 901
C ++PC G F C C G +G+ CE N+C PC N C D N F C C F G C+ + + C + C NGG C+ + G F CKC GF G C + C P C C P FC C G+TG C E+P+ C + C +CK + +GSP C
Sbjct: 478 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNG-FQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD-QPGAFHCKCLPGFEGPRCQTEVDECLSDP------CPVGASCLDLPG-AFFCLCPSGFTGQLC----EVPL---CAPNLCQPKQICKDQKDKANCLCPDGSPGC 657 HSP 12 Score: 58.9214 bits (141), Expect = 7.352e-8 Identity = 53/171 (30.99%), Postives = 69/171 (40.35%), Query Frame = 2
Query: 353 PCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP--CKNGGTC-------------IDKKNSQFTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDK 808
PC NG C+ + C C G+ GETC+ D QN C+NGG+C F C C F G C Q E+PC C G C +G QC C G+ GE C +++ C N G C YP + C C PG+ G C++
Sbjct: 33 PCANGGTCLSLSLGQGTCQCAPGFLGETCQ--FPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFC-------SANPCVNGGVCLATYPQIQ--CHCPPGFEGHACER 192
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Match: lin-12 (pep chromosome:WBcel235:III:9060096:9071760:-1 gene:WBGene00003001.1 transcript:R107.8.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-12) HSP 1 Score: 149.443 bits (376), Expect = 4.974e-36 Identity = 133/474 (28.06%), Postives = 192/474 (40.51%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTS---------------------------------------------------QFIGNLCQF----------ENPCLNVNCENGGTCESLENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNL-CKASFENGICDQQCNTFACNYDGGDC----DPWRKC-YGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCK-----FHKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTV 1528
+S +C N NG CV FRC C G+ G+ C+E +N C C+N GTC+ + C C + F GN C+ EN CL+ C N TC ++ + + C C+ GF G+ C C P +C+ H E + C C PG+ G+ C+++K C C NGGVC + CEC F+G C E IN+ F EK +++ S+C+ C +G CD CN AC +DGGDC +P+ KC YGN C F +GVCN CNN +CL+DG DC + + C+ + N ICD ECN+ CGFDGGDC + + +N + + + + F + L ++SS+LR+ V +
Sbjct: 370 LSENMCLN----NGTCVN-LPGSFRCDCARGFGGKWCDEPLNMCQDFHCENDGTCMHTSDHSPVCQCKNGFIGKRCEKECPIGFGGVRCDLRLEIGICSRQGGKCFNGGKCLSGFCVCPPDFTGNQCEVNRKNGKSSLSENLCLSDPCMNNATCIDVDAHIGYACICKQGFEGDICERHKDLCLENPCSNGGVCHQHRE-------SFSCDCPPGFYGNGCEQEKMFR----CLKSTCQNGGVCINEEEKGRKCECSYGFSGARC---------EEKINLT---GFTEKDSLLR-----SVCEKRKCSERANDGNCDADCNYAACKFDGGDCSGKREPFSKCRYGN---MCADFFANGVCNQACNNEECLYDGMDCLPAVVRCPVKIREHCASRFANGICDPECNTNGCGFDGGDCDNETNATIITN--------------IRITVQMDPKEFQVTGGQSLMEISSALRVTVRI 793 HSP 2 Score: 103.219 bits (256), Expect = 7.266e-22 Identity = 127/436 (29.13%), Postives = 173/436 (39.68%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNG-------------------------------------GTCIDKKNSQ--FTCNCTSQFIGNLC-QFENPCLNVN-CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDK---------KKELPVEIGC---KSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKT-FNEKQLIIKKTKSPSLCDNLCKASFENGICDQQ---CNTFACNYDGGDCDPWRKC---------YGNDLKHCKGVF--------NDGVC-NPECNNVDCL----FDGEDCH---------------KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTSR 1366
C++ PC +G C+ +F F+C C G+ G C+E ++C+ N C+ G GTCID S+ F C C + G LC Q +N CL+ N C N GTC +L G F+C C GF G++C C C N G C + + C+C G+ G RC+K + +L +EIG + CFNGG C S C C +FTG C + K + N+ + N I C +CK FE IC++ C C+ +GG C R+ YGN + K +F N GVC N E C F G C +S C+ KCSE + CD +CN C FDGGDC R
Sbjct: 254 CASNPCSHGVCI-SFSGGFQCICDDGYSGSYCQEGKDNCVNNKCEAGSKCINGVNSYFCDCPPERTGPYCEKMDCSAIPDICNHGTCIDSPLSEKAFECQCEPGYEGILCEQDKNECLSENMCLNNGTCVNLP-GSFRCDCARGFGGKWCDEPLNMCQDF------HCENDGTCMHTSDHSPVCQCKNGFIGKRCEKECPIGFGGVRCDLRLEIGICSRQGGKCFNGGKCL-----SGFCVCPPDFTGNQCEVNRKNGKSSLSENLCLSDPCMNNATCIDVDAHIGYAC--ICKQGFEGDICERHKDLCLENPCS-NGGVCHQHRESFSCDCPPGFYGNGCEQEK-MFRCLKSTCQNGGVCINEEEKGRKCECSYGFSGARCEEKINLTGFTEKDSLLRSVCEKRKCSERANDGNCDADCNYAACKFDGGDCSGKR 672
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Match: glp-1 (pep chromosome:WBcel235:III:9092241:9099698:1 gene:WBGene00001609.1 transcript:F02A9.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:glp-1) HSP 1 Score: 141.354 bits (355), Expect = 1.744e-33 Identity = 151/561 (26.92%), Postives = 224/561 (39.93%), Query Frame = 2
Query: 356 CVNGKCVEAFDPE--FRCSCWHGWKGETCEENVNDC-IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQ------NIACPVIPKKKR-----ELCNNHGECDIYPNMTLFCKCDPGYTGDRCD---KKKELPVEIGCK---------------SDY-----------------------CFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKET-RKEALINIKIPKTFN-------------EKQLIIKKTKSPSLCD----NLCKASFENGICDQQCNTFACNYDGGDCD----PWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKS--SCKFH---KCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTV-----------------FNVTEINFN-FATALLIKLHV-NYTQCVLYGGQCFSSLEQI--SNFLKAGIEKGNVLSLPFRLARVDTRI 1726
C +G+C+ D + FRC C G++GE C ++ N+C I+ C N TC + + FTC C + G C+ + C + C+N G C N M C C GF G+ C ++ I C + ++ C N G C + FC C+P Y GDRC+ K + P CK S Y C NGG C+ + NG C C F+G C I ++ + N + K E+ L+I+K+K + D C NGIC+ +CN CN+DGGDC P+ KC C F +GVCN ECNN +CL+DG DC C H C E + +C+ EC+ CGFDGGDC+ S ++ + + F E L ++S++LR V + E+N + ++ HV Y Q V+ G + +E+I F + + V + L + D R+
Sbjct: 201 CNHGRCIPNRDEDKNFRCVCDSGYEGEFCNKDKNECLIEETCVNNSTCFNL-HGDFTCTCKPGYAGKYCEEAIDMCKDYVCQNDGYCAHDSNQMPICYCEQGFTGQRCEIECPSGFGGIHCDLPLQRPHCSRSNGTCYNDGRC-----INGFCVCEPDYIGDRCEINRKDFKFPDIQSCKYNPCVNNATCIDLKNSGYSCHCPLGFYGLNCEQHLLCTPTTCANGGTCEGV-NGVIRCNCPNGFSGDYCEIKDRQLCSRHPCKNGGVCKNTGYCECQYGYTGPTCEEVLVIEKSKETVIRDLCEQRKCMDLASNGICNPECNLEECNFDGGDCSGGQRPFSKC--QYPARCADQFANGVCNQECNNEECLYDGLDCQSELFRCPAHIRKHCIERRGDGVCNLECSFIGCGFDGGDCNNGTEAIILS--------------DIRIKVQIDPIEFQATGGETLMQISANLRATVRIQRDELGPLVFRWDGEHEMERVEMNSSKLEDQFVLSHHVRRYRQAVVTGIVLYLEVEEICKPEFCRFSTAQSVVDLIAAGLVKSDGRM 738 HSP 2 Score: 125.946 bits (315), Expect = 7.952e-29 Identity = 109/330 (33.03%), Postives = 146/330 (44.24%), Query Frame = 2
Query: 344 SNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVND--------CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNH-----GECDIYPNMTLFCKCDPGYTGDRC------DKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGE---FTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDP-WRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSS 1261
SN C N G+C+ F C C + G+ CE N D C NPC N TCID KNS ++C+C F G C+ C C NGGTCE + NG+ +C C GF G++C + K R+LC+ H G C T +C+C GYTG C +K KE + C+ C + + NG EC E F G +C+ Q K + P+ C + F NG+C+Q+CN C YDG DC +C + KHC DGVCN EC+ + C FDG DC+ +
Sbjct: 332 SNGTCYNDGRCINGF-----CVCEPDYIGDRCEINRKDFKFPDIQSCKYNPCVNNATCIDLKNSGYSCHCPLGFYGLNCEQHLLCTPTTCANGGTCEGV-NGVIRCNCPNGFSGDYCEI----------KDRQLCSRHPCKNGGVC----KNTGYCECQYGYTGPTCEEVLVIEKSKETVIRDLCEQRKCMD-----LASNGICNPECNLEECNFDGGDCS---------------------GGQRPFSKCQYPARCAD----QFANGVCNQECNNEECLYDGLDCQSELFRCPAHIRKHCIERRGDGVCNLECSFIGCGFDGGDCNNGT 611 HSP 3 Score: 91.6633 bits (226), Expect = 2.747e-18 Identity = 69/203 (33.99%), Postives = 96/203 (47.29%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTC--ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C + PC NG C F F+C C +G+ G CEE ++ C QN C G TC++ + + C+C G C+ L N N G C E+ F+C C G+ GEFC C + E C N+ C +++ + T C C PGY G C++ ++ CK C N G C N PIC C+ FTG+ C I
Sbjct: 121 CDSDPCNNGLCY-PFYGGFQCICNNGYGGSYCEEGIDHCAQNECAEGSTCVNSVYNYY-CDCPIGKSGRYCERTECALMGNICNHGRCIPNRDEDKNFRCVCDSGYEGEFCNKDKNECLI-----EETCVNNSTCFNLHGDFT--CTCKPGYAGKYCEEAIDM-----CKDYVCQNDGYCAHDSNQMPICYCEQGFTGQRCEI 309
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Match: slt-1 (Slit homolog 1 protein [Source:UniProtKB/Swiss-Prot;Acc:G5EFX6]) HSP 1 Score: 93.9745 bits (232), Expect = 6.036e-19 Identity = 70/204 (34.31%), Postives = 99/204 (48.53%), Query Frame = 2
Query: 338 LCSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
LC N PC N C ++ C+C G+ G CE ++ C +PC N TC + +F C C F G+ C+ + C+N CENGG C L N ++C C + G+ C + C KK C N+G+C I N + C C PG+TG+ C+ + CK+ C NGG C V S C C+ + G+ C IP
Sbjct: 872 LCLNSPCKNNAICETTSSRKYTCNCTPGFYGVHCENQIDACYGSPCLNNATCKVAQAGRFNCYCNKGFEGDYCEKNIDDCVNSKCENGGKCVDLINS-YRCDCPMEYEGKHCEDKLEYC----TKKLNPCENNGKC-IPINGSYSCMCSPGFTGNNCETNID-----DCKNVECQNGGSC-VDGILSYDCLCRPGYAGQYCEIP 1063 HSP 2 Score: 87.0409 bits (214), Expect = 6.637e-17 Identity = 65/206 (31.55%), Postives = 96/206 (46.60%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ--FENPCLNVN-CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEI----GCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C PC+N C A F C C G++G+ CE+N++DC+ + C+NGG C+D NS + C+C ++ G C+ E +N CEN G C + NG + C C GF G C C K C N G C + ++ C C PGY G C+ + +E C+ C G ++ C+C F+G +C
Sbjct: 912 CYGSPCLNNATCKVAQAGRFNCYCNKGFEGDYCEKNIDDCVNSKCENGGKCVDLINS-YRCDCPMEYEGKHCEDKLEYCTKKLNPCENNGKCIPI-NGSYSCMCSPGFTGNNCETNIDDC------KNVECQNGGSC-VDGILSYDCLCRPGYAGQYCEIPPMMDMEYQKTDACQQSACGQGECVASQNSSDFTCKCHEGFSGPSC 1108 HSP 3 Score: 60.4622 bits (145), Expect = 8.440e-9 Identity = 48/142 (33.80%), Postives = 65/142 (45.77%), Query Frame = 2
Query: 509 QFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
QFTC+ S+ L + CLN C+N CE+ + + C C GF G C Q AC P C N+ C + C C+ G+ GD C+K + C + C NGG C L N S C+C E+ GK+C
Sbjct: 855 QFTCD--SKVPTKLATKCDLCLNSPCKNNAICETTSSRKYTCNCTPGFYGVHCENQIDACYGSP------CLNNATCKVAQAGRFNCYCNKGFEGDYCEKNID-----DCVNSKCENGGKCVDLIN-SYRCDCPMEYEGKHC 982
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Match: clec-78 (C-type LECtin [Source:UniProtKB/TrEMBL;Acc:Q20531]) HSP 1 Score: 85.8853 bits (211), Expect = 1.735e-16 Identity = 62/205 (30.24%), Postives = 90/205 (43.90%), Query Frame = 2
Query: 326 VSSKLCSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
V C++ PC+N +CV+ ++C C GW G CE++ C PC+N G C+ F C C G C+ N C+ C NGG C +C C F G+ C +N C + C N G+C C+C PG+TG+RC+ + C + +C +G C V + IC C TG +C
Sbjct: 2359 VKQDQCADSPCLNDAQCVD-MGGAYKCVCKSGWTGPKCEQDNGSCAAKPCRNNGFCVSLVADYF-CVCPPGVSGKNCESAPNRCIGQPCHNGGECGDF-GSHLECACPASFTGKGCEFKNTGC--------KTCENGGKCAEAAGGLQKCECSPGFTGERCETNIDE-----CSTAHCPSGATC-VDQVNTHICVCPFNLTGVHC 2546 HSP 2 Score: 78.9518 bits (193), Expect = 2.264e-14 Identity = 71/213 (33.33%), Postives = 89/213 (41.78%), Query Frame = 2
Query: 311 CLLVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C + S+K+C N N +C F +C C G+ G+ CE + C PC NGG C ++ + + C C F G CQFE + C V C NGG C L C CR GF G C C C N C I + F C+C PG+ G CDK + C C C L N CEC F+GK C I
Sbjct: 2012 CFPIDCSAKMCEN----NAEC-SVFMHRAQCHCKPGYVGDRCEMLEDVCSTQPCYNGGKC-EQVGTTYKCTCPKMFNGARCQFESDECNGVKCPNGGVCHDLPGVKSTTCLCRTGFAGPQCEEITDIC-----STNNPCRNGARC-IGEKLGRFKCQCVPGWEGPNCDKNID-----DCADSPCALNATCVDLINDYK-CECPTGFSGKRCHI 2206 HSP 3 Score: 77.0258 bits (188), Expect = 9.892e-14 Identity = 64/210 (30.48%), Postives = 93/210 (44.29%), Query Frame = 2
Query: 332 SKLCS-NRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
+ +CS N PC NG +C+ F+C C GW+G C++N++DC +PC TC+D N + C C + F G C EN C + C +G + L + QC C+ G+ GE C C P C N +C I C+C GY G C + C C N C + + C+C F G +C + + E
Sbjct: 2130 TDICSTNNPCRNGARCIGEKLGRFKCQCVPGWEGPNCDKNIDDCADSPCALNATCVDLIN-DYKCECPTGFSGKRCHIKENLCASSPCVHGLCIDKLYS--RQCLCQPGWTGENCDQNIDECAASP------CQNDAKC-IDEINGYMCECADGYEGVHCQHLVDH-----CAKQPCHNNATCTNM-GATYHCDCTLGFDGVHCEMNIDE 2323 HSP 4 Score: 74.3294 bits (181), Expect = 6.476e-13 Identity = 62/188 (32.98%), Postives = 83/188 (44.15%), Query Frame = 2
Query: 392 EFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
+F+C C G+ G C+ + C +PC N C+D + + C C S + G C+ +N C C N G C SL F C C G G+ C C P C+N GEC + + L C C +TG C+ K GCK+ C NGG C G CEC FTG+ C + E
Sbjct: 2343 DFKCVCKPGYTGPRCDVKQDQCADSPCLNDAQCVDMGGA-YKCVCKSGWTGPKCEQDNGSCAAKPCRNNGFCVSLVADYF-CVCPPGVSGKNCESAPNRCIGQP------CHNGGECGDFGSH-LECACPASFTGKGCEFKN-----TGCKT--CENGGKCAEAAGGLQKCECSPGFTGERCETNIDE 2514
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Match: crb-1 (Drosophila CRumBs homolog [Source:UniProtKB/TrEMBL;Acc:Q19350]) HSP 1 Score: 82.0333 bits (201), Expect = 2.746e-15 Identity = 70/231 (30.30%), Postives = 105/231 (45.45%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVND---------------------------------CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK--RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNC 934
C++G CV+ E C C GW G C+ V D C + C+N GTC+ +N C C F+G+ C+ E+ C C+NG CE+L+ G ++CKC GF G++C +Q+ KK+ + C+N+G+C I L CKC PG+ G C+ K E+ E C++ VC +++ S CEC F G +C
Sbjct: 63 CLHGNCVKGTFGEETCQCSEGWMGSLCDNLVTDDDTAQKCSPQCGDDERCTKGADGSYICQSNEPSCATHTCQNNGTCV-AENGNVKCACPPGFVGDHCETDEDECKENFCQNGADCENLK-GSYECKCLKGFSGKYCEIQD-------KKQCTSDYCHNNGQC-ISTGSDLSCKCSPGFDGAFCELKAEVN-ECICENP----AHVCSLVNGTSRTTQCECPSGFMGADC 278 HSP 2 Score: 76.2554 bits (186), Expect = 1.654e-13 Identity = 94/359 (26.18%), Postives = 153/359 (42.62%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENP--CLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCN----NHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTK--SPSLCD---NLCKASFENGICDQ---QCNTFACN--YDGGDCDPWRKCYGNDLKHCKG--VFNDGVCNPECNNVDCL----FDGEDCH----KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHT 1360
+G C++ D E +C C +G+ GE CE ++C C NGG C+ ++ + C C + ++G+ C C + C+N G C + F+C C G+ GE C +++ CN N G C + C+C+ GYTG C+K C S+ C + G C + N + +C C + G +C + N + +T +E + K + C+ + KA +G C Q + +T +CN Y+G CD + +CK N C + C F+G DC + + +F K ++KI D EC GF+G +C T
Sbjct: 1224 HGYCLDGID-EAKCICNNGFHGEHCELAKDECEGVECHNGGKCVKNRSEKIVCQCGNSWMGDSCNVTKTTNCKDSPCQNFGQCMQKTDTFFECNCMDGYSGELCEQRDV----------NECNHYDCNRGHC-VMTVSGPACQCEMGYTGRFCEKLLNQ-----CSSNTCSSRGACSPVWNNT-VCNCDNNWRGAHCQHQMDTCLDFPCNNDGVCRTNDENTFSCECQKFFMGTRCEIEGSCLKAQCVHGECIQLSPETHTCSCNIGYEGDACD-------KKIDYCKAGPCLNGANCENKLTGYKCTCAVGFEGADCEINIDECALEFCKNGAKCRDKINDYECVCDGTGFEGRNCTT 1557 HSP 3 Score: 73.559 bits (179), Expect = 9.037e-13 Identity = 65/215 (30.23%), Postives = 95/215 (44.19%), Query Frame = 2
Query: 314 LLVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGE-FTGKNCTIPLKE 952
LL SS CS+R G C ++ C+C + W+G C+ ++ C+ PC N G C + F+C C F+G C+ E CL C + G C L C C G+ G+ C + C P C N C+ +T + C C G+ G C E+ ++ C ++C NG C+ N C C G F G+NCT + E
Sbjct: 1367 LLNQCSSNTCSSR----GACSPVWNNTV-CNCDNNWRGAHCQHQMDTCLDFPCNNDGVCRTNDENTFSCECQKFFMGTRCEIEGSCLKAQCVH-GECIQLSPETHTCSCNIGYEGDACDKKIDYCKAGP------CLNGANCE--NKLTGYKCTCAVGFEGADC----EINID-ECALEFCKNGAKCRDKINDYE-CVCDGTGFEGRNCTTDINE 1561 HSP 4 Score: 73.1738 bits (178), Expect = 1.164e-12 Identity = 61/201 (30.35%), Postives = 96/201 (47.76%), Query Frame = 2
Query: 356 CVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C+NG CV+ ++ +C C G+ GE CE+NVNDC C G C+D + + C C + F G C+ ++ C V C NGG C + C+C ++G+ C V K C N G+C + C C GY+G+ C+++ ++ + Y N G C V+ P C+C+ +TG+ C L +
Sbjct: 1183 CLNGATCVDIWNKR-KCVCPAGFAGENCEDNVNDCKFVDCGKHGYCLDGID-EAKCICNNGFHGEHCELAKDECEGVECHNGGKCVKNRSEKIVCQCGNSWMGDSCNVTKTT-----NCKDSPCQNFGQCMQKTDTFFECNCMDGYSGELCEQR-----DVNECNHYDCNRGHC-VMTVSGPACQCEMGYTGRFCEKLLNQ 1370 HSP 5 Score: 72.0182 bits (175), Expect = 2.620e-12 Identity = 62/199 (31.16%), Postives = 95/199 (47.74%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN--PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPL 946
NG CV A + +C+C G+ G+ CE + ++C +N C+NG C + K S + C C F G C+ ++ C + C N G C S + + CKC GF G FC ++ I + +C+ + T C+C G+ G C + + P C + C NGG C +D+G + C C FTG C P+
Sbjct: 137 NGTCV-AENGNVKCACPPGFVGDHCETDEDECKENFCQNGADCENLKGS-YECKCLKGFSGKYCEIQDKKQCTSDYCHNNGQCISTGSDL-SCKCSPGFDGAFCELKAEVNECICENPAHVCSLVNG----TSRTTQCECPSGFMGADCKELQARP----CDREPCLNGGHC--VDDGQNLFTCFCLPSFTGIYCGEPV 322 HSP 6 Score: 70.8626 bits (172), Expect = 6.862e-12 Identity = 63/210 (30.00%), Postives = 88/210 (41.90%), Query Frame = 2
Query: 323 IVSSKLCSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCE--ENVNDCI-QNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF--ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
I K C++ C N G+C+ + C C G+ G CE VN+CI +NP + + ++ + C C S F+G C+ PC C NGG C +F C C F G +C PV C N G+C ++ C+C G+ G C+ C C NGG CK+ G P C C+ F G C
Sbjct: 200 IQDKKQCTSDYCHNNGQCIST-GSDLSCKCSPGFDGAFCELKAEVNECICENP-AHVCSLVNGTSRTTQCECPSGFMGADCKELQARPCDREPCLNGGHCVDDGQNLFTCFCLPSFTGIYCGE-----PVDCLVNGSDCKNGGKC-VFALAATTCQCPEGFNGSNCEISNSYRSHPTCSDIRCLNGGSCKLDAEGEPFCVCEEGFDGPFC 401 HSP 7 Score: 70.4774 bits (171), Expect = 7.921e-12 Identity = 60/169 (35.50%), Postives = 82/169 (48.52%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCT-SQFIGNLCQFE-NPCLNVN-CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK-RELCNNHGEC-----DIYPNMTLF---CKCDPGYTGDRCDKK 811
C PC+NG E ++C+C G++G CE N+++C CKNG C DK N + C C + F G C + N C N N C NG +L G ++C CR GFIG C+V+N I + HG+C I N + C CD GYTG C ++
Sbjct: 1485 CKAGPCLNGANCENKLTGYKCTCAVGFEGADCEINIDECALEFCKNGAKCRDKIN-DYECVCDGTGFEGRNCTTDINECANPNNCINGECTNTL--GNYKCACRNGFIGPRCSVRNPCTAQIASNNISSVTCVHGKCVNPVVQIEKNREVAKYECACDRGYTGPTCSQR 1650 HSP 8 Score: 58.5362 bits (140), Expect = 3.838e-8 Identity = 72/264 (27.27%), Postives = 100/264 (37.88%), Query Frame = 2
Query: 365 GKCVEAFDPEFRCSCWHGWKGETCE-----ENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIP-------------------KKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI---CECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFEN 1075
GKCV A C C G+ G CE + C C NGG+C + C C F G C+ ++ C C+NGGTC+ + G + C C GF G C + IP K E C N C + C CD GY G +CD+K + ++ C S G C +++ I C C+ G+ C + TF+ K L I ++ S L +SFEN
Sbjct: 335 GKCVFAL-AATTCQCPEGFNGSNCEISNSYRSHPTCSDIRCLNGGSCKLDAEGEPFCVCEEGFDGPFCEPKSGCTINPCQNGGTCQDAD-GQYFCHCTSGFGGVHCETVDEPSTPIPTLGTFPSFTTSGIDGFSQSKISCEDCVNSSNC-LDVESGPVCICDDGYFGQKCDQKHDKCSKVSCPS-----GQTCSQVNDNVNITAQCGCEIGHFGQQC-------------EMVTSATFSAKSLYIHQSSKFS----LGTSSFEN 573 HSP 9 Score: 58.151 bits (139), Expect = 4.986e-8 Identity = 59/196 (30.10%), Postives = 81/196 (41.33%), Query Frame = 2
Query: 455 CIQNPCKNGGTC-IDKKNSQFTCNCTSQFIGNLCQF--ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFC--------------------------AVQNIACPV-IPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C +N C NGGTC ++ + F C C F G LCQ CL+ NC G G C+C G++G C A + C P C N+G C + N + C C PG+ GD C+ ++ CK ++C NG C+ L GS C+C F+GK C I K+
Sbjct: 22 CSRNTCLNGGTCTVNDETRMFQCECPKGFSGLLCQDNCSLHCLHGNCVKGTF------GEETCQCSEGWMGSLCDNLVTDDDTAQKCSPQCGDDERCTKGADGSYICQSNEPSCATHTCQNNGTC-VAENGNVKCACPPGFVGDHCETDEDE-----CKENFCQNGADCENL-KGSYECKCLKGFSGKYCEIQDKK 204 HSP 10 Score: 54.6842 bits (130), Expect = 5.813e-7 Identity = 68/241 (28.22%), Postives = 100/241 (41.49%), Query Frame = 2
Query: 299 FILGCLLVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCR-YGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGC---KSDYCFNGG----VCKVLDNGSPI---CECKGEFTGKNCTIPLKETRKEALINIK 982
F +G I S C CV+G+C++ CSC G++G+ C++ ++ C PC NG C + K + + C C F G C+ + C C+NG C N ++C C GF G C C C N GEC + N C C G+ G RC + +I S C +G V ++ N C C +TG C+ +KE+ A+ NI
Sbjct: 1435 FFMGTRCEIEGS--CLKAQCVHGECIQLSPETHTCSCNIGYEGDACDKKIDYCKAGPCLNGANC-ENKLTGYKCTCAVGFEGADCEINIDECALEFCKNGAKCRDKIND-YECVCDGTGFEGRNCTTDINECA-----NPNNCIN-GECTNTLGNYK--CACRNGFIGPRCSVRNPCTAQIASNNISSVTCVHGKCVNPVVQIEKNREVAKYECACDRGYTGPTCSQRIKES---AMSNIS 1660
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Match: N (gene:FBgn0004647 transcript:FBtr0304659) HSP 1 Score: 121.709 bits (304), Expect = 3.068e-27 Identity = 124/470 (26.38%), Postives = 200/470 (42.55%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEAL-------------INIKIPK-TFNEK-QLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKC--------------YGNDLKH---------CKGVFNDGVCNPECNNVDCLFDGEDCHK-----SSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTSR------------------------SNSFFSNEGLTKCSTQTK---LYE--LDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTV 1528
C ++PC NG + C C G++G+ CE N++DC NPC+NGGTC D+ F+C+C +G +C+ ++ C C N G+C G F+C C+ GF+G C C P C+N G D + + C C PG+ G C+ K + C C NGG C + +G C C F GKNC + ++ + P+ T E ++ SP+ C A+ E+ + D +C + + G CD + Y DL+ C +G+C+ +CN C FDG DC ++C ++C ++N C+EECN+ C +DG DC +N+ S +GL C +T+ L E + +V++ ++ F + +++FL+ +S LR V +
Sbjct: 1187 CQSQPCQNGGTCRDLIGAYECQCRQGFQGQNCELNIDDCAPNPCQNGGTCHDRV-MNFSCSCPPGTMGIICEINKDDCKPGACHNNGSCIDRVGG-FECVCQPGFVGARCEGDINECLSNP------CSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDF-----CAQSPCQNGGNCNIRQSGH-HCICNNGFYGKNCELSGQDCDSNPCRVGNCVVADEGFGYRCECPRGTLGEHCEIDTLDECSPNPCAQ--GAACEDLLGDYECLCPS-KWKGKRCDIYDANYPGWNGGSGSGNDRYAADLEQQRAMCDKRGCTEKQGNGICDSDCNTYACNFDGNDCSLGINPWANCTANECWNKFKNGKCNEECNNAACHYDGHDCERKLKSCDSLFDAYCQKHYGDGFCDYGCNNAECSWDGL-DCENKTQSPVLAEGAMSVVMLMNVEAFREIQAQFLRNMSHMLRTTVRL 1638 HSP 2 Score: 115.161 bits (287), Expect = 2.970e-25 Identity = 112/375 (29.87%), Postives = 166/375 (44.27%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLC-QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE----------TRKEALINIKI---PKTFNEKQLIIKKTKSPSLCDN-------------LCKASFENGICD---QQCNTFACNYDGG-DCDPWRKCY------GNDLKHCKGVF---------NDGVCNPE-------CNNV----DCLFDGEDCHKSSCKFHKC 1279
C+ C+NG C++ + + CSC G+ G C+ +N C NPC NG TC ++N+++TC+C S F G C ++ + C CENG TC +++ F CKC G+ G+ C VQ I+C +K R+LCNN G C Y N + C C GY G C K+ + C+S C NGG C+ L G+ C+C+ F G+NC + + + T + ++N P T I K P C N +C+ F C+ +C + C+ G DC Y G+ +HC+ N G CN CNN +C G+DC + C+ C
Sbjct: 1026 CTESSCLNGGSCIDGIN-GYNCSCLAGYSGANCQYKLNKCDSNPCLNGATC-HEQNNEYTCHCPSGFTGKQCSEYVDWCGQSPCENGATCSQMKH-QFSCKCSAGWTGKLCDVQTISCQDAADRKGLSLRQLCNN-GTCKDYGN-SHVCYCSQGYAGSYCQKEIDE-----CQSQPCQNGGTCRDLI-GAYECQCRQGFQGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCKPGACHNNGSCIDRVGGFECVCQPGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDFCAQSPCQNGGNCNIRQSGHHCICNNGFYGKNCELSGQDCDSNPCRVGNC 1389 HSP 3 Score: 94.3597 bits (233), Expect = 5.736e-19 Identity = 71/203 (34.98%), Postives = 102/203 (50.25%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C++ PCVN G+C + + EF C C G+ G+ CE ++++C NPC++GGTC DK N+ F+C C + G C+ + C+ C NGGTC NG ++C C+ F G C + C C N +C N F C C GYTG CD+ ++ S C NG C + GS C C + G++C I
Sbjct: 757 CASNPCVNEGRCEDGIN-EFICHCPPGYTGKRCELDIDECSSNPCQHGGTCYDKLNA-FSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNG-YKCVCKVPFTGRDCESKMDPC------ASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDED----IDECSLSSPCRNGASCLNVP-GSYRCLCTKGYEGRDCAI 945 HSP 4 Score: 92.8189 bits (229), Expect = 1.762e-18 Identity = 73/200 (36.50%), Postives = 95/200 (47.50%), Query Frame = 2
Query: 341 CSNRPC-VNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PC +G C + + C C G G+ CE NVN+C NPC NG TCID NS + C C F G C+ + C++ C N G C NG ++C+C GF C C P C N G C+ N C C PGYTG RC EL ++ C S+ C +GG C N C+C +TG+ C
Sbjct: 643 CESNPCQFDGHCQDRVG-SYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINS-YKCQCVPGFTGQHCEKNVDECISSPCANNGVCIDQVNG-YKCECPRGFYDAHCLSDVDECASNP------CVNEGRCEDGIN-EFICHCPPGYTGKRC----ELDIDE-CSSNPCQHGGTCYDKLNAFS-CQCMPGYTGQKC 826 HSP 5 Score: 92.4337 bits (228), Expect = 2.388e-18 Identity = 59/173 (34.10%), Postives = 82/173 (47.40%), Query Frame = 2
Query: 455 CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCE-SLENGM--FQCKCRYGFIGEFCAVQNIACPVIPKKKREL-CNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI-CECKGEFTGKNCTIPLKETR 958
C C+NGGTC+ + N + C C S ++G+ C+ NPC ++ C+NGGTC+ + NG CKC GF C + +P + C N G C + C C GYTG+RC+ K C S C NG C L S C C FTG C+ ++E +
Sbjct: 62 CTSVGCQNGGTCVTQLNGKTYCACDSHYVGDYCEHRNPCNSMRCQNGGTCQVTFRNGRPGISCKCPLGFDESLCEI------AVPNACDHVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNL------CASSPCRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEECQ 222 HSP 6 Score: 89.3521 bits (220), Expect = 2.124e-17 Identity = 68/196 (34.69%), Postives = 86/196 (43.88%), Query Frame = 2
Query: 353 PCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCT 937
PC NG +RC C G++G C N +DC PC+NGGTC+D ++C C F G C+ + N CL+ C+NG TC N + C C GF G C + C C N G C I C C GY+G C K C S+ C NG C +N C C FTGK C+
Sbjct: 916 PCRNGASCLNVPGSYRCLCTKGYEGRDCAINTDDCASFPCQNGGTCLDGI-GDYSCLCVDGFDGKHCETDINECLSQPCQNGATCSQYVN-SYTCTCPLGFSGINCQTNDEDC------TESSCLNGGSC-IDGINGYNCSCLAGYSGANCQYKLNK-----CDSNPCLNGATCHEQNN-EYTCHCPSGFTGKQCS 1096 HSP 7 Score: 87.8113 bits (216), Expect = 6.467e-17 Identity = 105/375 (28.00%), Postives = 149/375 (39.73%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI---PLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDN--------------------------LCKASFENGIC---DQQCNTFACNYDGGDCDPWRKCY------GNDLKHCKGVFNDGVCNPECNN---------------------VDCLFDGEDCHKSSC 1264
V+ C + PC NG C++ + ++C C G+ G+ CE+NV++CI +PC N G CID+ N + C C F C + + C + C N G CE N F C C G+ G+ C + C P C + G C Y + F C+C PGYTG +C+ + C ++ C NGG C NG C CK FTG++C P R + F + K + CD LC +E C C +F C +GG C Y G D KHC+ N+ + P C N ++C + EDC +SSC
Sbjct: 676 VNVNECHSNPCNNGATCIDGIN-SYKCQCVPGFTGQHCEKNVDECISSPCANNGVCIDQVNG-YKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGIN-EFICHCPPGYTGKRCELDIDECSSNP------CQHGGTC--YDKLNAFSCQCMPGYTGQKCETNID-----DCVTNPCGNGGTCIDKVNGYK-CVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTKGYEGRDCAINTDDCASFPCQ-NGGTCLDGIGDYSCLCVDGFDGKHCETDINECLSQP-CQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSC 1031 HSP 8 Score: 87.0409 bits (214), Expect = 1.158e-16 Identity = 73/224 (32.59%), Postives = 105/224 (46.88%), Query Frame = 2
Query: 329 SSKLCSNRPCVNGKCVEAF--DPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCD------KKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEA 967
+ LC++ PC NG A F CSC G+ G+TC ++ +C NPCK GGTC++ S + C C + + G C + PC C+NGG C S NG+ ++CKC GF G+ C C LC N G C D + T C+C P +TG C +++ PV C NG C +GS C C + G +C+ + ++ A
Sbjct: 177 TKNLCASSPCRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEECQSNPCKYGGTCVNTHGS-YQCMCPTGYTGKDCDTKYKPCSPSPCQNGGICRS--NGLSYECKCPKGFEGKNCEQNYDDC------LGHLCQNGGTCIDGISDYT--CRCPPNFTGRFCQDDVDECAQRDHPV--------CQNGATCTNT-HGSYSCICVNGWAGLDCSNNTDDCKQAA 380 HSP 9 Score: 85.1149 bits (209), Expect = 3.803e-16 Identity = 68/186 (36.56%), Postives = 85/186 (45.70%), Query Frame = 2
Query: 389 PEFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNG-SPICECKGEFTGKNC 934
P C C G+ CE V N C C NGGTC K ++TC C + + G C+ +N C + C NG TC +L + F C C GF G+ C+ C P K C N HG + C C GYTG CD K + C C NGG+C+ NG S C+C F GKNC
Sbjct: 120 PGISCKCPLGFDESLCEIAVPNACDHVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNLCASSPCRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEECQSNPCKYGGTCVNTHG--------SYQCMCPTGYTGKDCDTKYKP-----CSPSPCQNGGICR--SNGLSYECKCPKGFEGKNC 290 HSP 10 Score: 84.3445 bits (207), Expect = 6.806e-16 Identity = 62/228 (27.19%), Postives = 112/228 (49.12%), Query Frame = 2
Query: 2276 LGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQETLRK 2953
L +++ GE+ +H+AAR + ++A + + D GRTPL +++AADA + + + LR + R TT LI A +L + M+ L+ + +N D+ G++ +HW+A NN+ E ++ + + D +D++D++PLFLAA EG+ ++ K LL F I MD P+ +A E+ ++I L+ E + +
Sbjct: 1943 LNATMDKTGETSLHLAARFARADAAKRLLDA--GADANCQDNTGRTPLHAAVAADA------MGVFQILLRNRATNLNAR--------------MHDGTTPLILAARLAIEGMVEDLITADADINAADNSGKTALHWAAAVNNT---EAVNILLMHHANRDAQDDKDETPLFLAAREGSYEACKALLDNFANREITDHMD---RLPRDVASERLHHDIVRLLDEHVPR 2142 HSP 11 Score: 84.3445 bits (207), Expect = 6.921e-16 Identity = 67/211 (31.75%), Postives = 99/211 (46.92%), Query Frame = 2
Query: 335 KLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVN---CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
K CS PC NG + + C C G++G+ CE+N +DC+ + C+NGGTCID S +TC C F G CQ + + C + C+NG TC + +G + C C G+ G C+ C K+ C C I + +C+C G TG C ++ C S+ C +C NGS C C + G +C+ + E
Sbjct: 257 KPCSPSPCQNGGICRSNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTCIDGI-SDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNT-HGSYSCICVNGWAGLDCSNNTDDC------KQAACFYGATC-IDGVGSFYCQCTKGKTGLLCH------LDDACTSNPCHADAICDTSPINGSYACSCATGYKGVDCSEDIDE 452 HSP 12 Score: 83.9593 bits (206), Expect = 9.699e-16 Identity = 74/225 (32.89%), Postives = 103/225 (45.78%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC-IDKKNSQ--FTCNCTSQFIGNLCQFE--NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKT 994
C++ C NG CV + + C+C + G+ CE N C C+NGGTC + +N + +C C F +LC+ N C +V C NGGTC+ + C C G+ GE C +N+ C P C N C + F C C PG+TGD C E C+S+ C GG C V +GS C C +TGK+C K N I ++
Sbjct: 62 CTSVGCQNGGTCVTQLNGKTYCACDSHYVGDYCEHR-NPCNSMRCQNGGTCQVTFRNGRPGISCKCPLGFDESLCEIAVPNACDHVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNL-CASSP------CRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEE-----CQSNPCKYGGTC-VNTHGSYQCMCPTGYTGKDCDTKYKPCSPSPCQNGGICRS 272 HSP 13 Score: 70.8626 bits (172), Expect = 9.514e-12 Identity = 74/251 (29.48%), Postives = 102/251 (40.64%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGT-------------------------------------CIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC+N G C + + F+CSC G+ G C+ N++DC PC+N G CID NS F C C + G +CQ + N C + C+ G C+ G + C+C+ G G+ C V C P CNN C I + C+C PG+TG C+K + C S C N GVC NG CEC F +C + E +N
Sbjct: 530 CQSNPCLNDGTCHDKIN-GFKCSCALGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCECPPGYTGTSCEININDCDSNPCHRGKCIDDVNS-FKCLCDPGYTGYICQKQINECESNPCQFDGHCQD-RVGSYYCQCQAGTSGKNCEVNVNECHSNP------CNNGATC-IDGINSYKCQCVPGFTGQHCEKNVDE-----CISSPCANNGVCIDQVNGYK-CECPRGFYDAHCLSDVDECASNPCVN 764
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Match: N (gene:FBgn0004647 transcript:FBtr0070507) HSP 1 Score: 121.709 bits (304), Expect = 3.068e-27 Identity = 124/470 (26.38%), Postives = 200/470 (42.55%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEAL-------------INIKIPK-TFNEK-QLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKC--------------YGNDLKH---------CKGVFNDGVCNPECNNVDCLFDGEDCHK-----SSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTSR------------------------SNSFFSNEGLTKCSTQTK---LYE--LDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTV 1528
C ++PC NG + C C G++G+ CE N++DC NPC+NGGTC D+ F+C+C +G +C+ ++ C C N G+C G F+C C+ GF+G C C P C+N G D + + C C PG+ G C+ K + C C NGG C + +G C C F GKNC + ++ + P+ T E ++ SP+ C A+ E+ + D +C + + G CD + Y DL+ C +G+C+ +CN C FDG DC ++C ++C ++N C+EECN+ C +DG DC +N+ S +GL C +T+ L E + +V++ ++ F + +++FL+ +S LR V +
Sbjct: 1187 CQSQPCQNGGTCRDLIGAYECQCRQGFQGQNCELNIDDCAPNPCQNGGTCHDRV-MNFSCSCPPGTMGIICEINKDDCKPGACHNNGSCIDRVGG-FECVCQPGFVGARCEGDINECLSNP------CSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDF-----CAQSPCQNGGNCNIRQSGH-HCICNNGFYGKNCELSGQDCDSNPCRVGNCVVADEGFGYRCECPRGTLGEHCEIDTLDECSPNPCAQ--GAACEDLLGDYECLCPS-KWKGKRCDIYDANYPGWNGGSGSGNDRYAADLEQQRAMCDKRGCTEKQGNGICDSDCNTYACNFDGNDCSLGINPWANCTANECWNKFKNGKCNEECNNAACHYDGHDCERKLKSCDSLFDAYCQKHYGDGFCDYGCNNAECSWDGL-DCENKTQSPVLAEGAMSVVMLMNVEAFREIQAQFLRNMSHMLRTTVRL 1638 HSP 2 Score: 115.161 bits (287), Expect = 2.970e-25 Identity = 112/375 (29.87%), Postives = 166/375 (44.27%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLC-QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE----------TRKEALINIKI---PKTFNEKQLIIKKTKSPSLCDN-------------LCKASFENGICD---QQCNTFACNYDGG-DCDPWRKCY------GNDLKHCKGVF---------NDGVCNPE-------CNNV----DCLFDGEDCHKSSCKFHKC 1279
C+ C+NG C++ + + CSC G+ G C+ +N C NPC NG TC ++N+++TC+C S F G C ++ + C CENG TC +++ F CKC G+ G+ C VQ I+C +K R+LCNN G C Y N + C C GY G C K+ + C+S C NGG C+ L G+ C+C+ F G+NC + + + T + ++N P T I K P C N +C+ F C+ +C + C+ G DC Y G+ +HC+ N G CN CNN +C G+DC + C+ C
Sbjct: 1026 CTESSCLNGGSCIDGIN-GYNCSCLAGYSGANCQYKLNKCDSNPCLNGATC-HEQNNEYTCHCPSGFTGKQCSEYVDWCGQSPCENGATCSQMKH-QFSCKCSAGWTGKLCDVQTISCQDAADRKGLSLRQLCNN-GTCKDYGN-SHVCYCSQGYAGSYCQKEIDE-----CQSQPCQNGGTCRDLI-GAYECQCRQGFQGQNCELNIDDCAPNPCQNGGTCHDRVMNFSCSCPPGTMGIICEINKDDCKPGACHNNGSCIDRVGGFECVCQPGFVGARCEGDINECLSNPCSNAGTLDCVQLVNNYHCNCRPGHMGRHCEHKVDFCAQSPCQNGGNCNIRQSGHHCICNNGFYGKNCELSGQDCDSNPCRVGNC 1389 HSP 3 Score: 94.3597 bits (233), Expect = 5.736e-19 Identity = 71/203 (34.98%), Postives = 102/203 (50.25%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C++ PCVN G+C + + EF C C G+ G+ CE ++++C NPC++GGTC DK N+ F+C C + G C+ + C+ C NGGTC NG ++C C+ F G C + C C N +C N F C C GYTG CD+ ++ S C NG C + GS C C + G++C I
Sbjct: 757 CASNPCVNEGRCEDGIN-EFICHCPPGYTGKRCELDIDECSSNPCQHGGTCYDKLNA-FSCQCMPGYTGQKCETNIDDCVTNPCGNGGTCIDKVNG-YKCVCKVPFTGRDCESKMDPC------ASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDED----IDECSLSSPCRNGASCLNVP-GSYRCLCTKGYEGRDCAI 945 HSP 4 Score: 92.8189 bits (229), Expect = 1.762e-18 Identity = 73/200 (36.50%), Postives = 95/200 (47.50%), Query Frame = 2
Query: 341 CSNRPC-VNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PC +G C + + C C G G+ CE NVN+C NPC NG TCID NS + C C F G C+ + C++ C N G C NG ++C+C GF C C P C N G C+ N C C PGYTG RC EL ++ C S+ C +GG C N C+C +TG+ C
Sbjct: 643 CESNPCQFDGHCQDRVG-SYYCQCQAGTSGKNCEVNVNECHSNPCNNGATCIDGINS-YKCQCVPGFTGQHCEKNVDECISSPCANNGVCIDQVNG-YKCECPRGFYDAHCLSDVDECASNP------CVNEGRCEDGIN-EFICHCPPGYTGKRC----ELDIDE-CSSNPCQHGGTCYDKLNAFS-CQCMPGYTGQKC 826 HSP 5 Score: 92.4337 bits (228), Expect = 2.388e-18 Identity = 59/173 (34.10%), Postives = 82/173 (47.40%), Query Frame = 2
Query: 455 CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCE-SLENGM--FQCKCRYGFIGEFCAVQNIACPVIPKKKREL-CNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI-CECKGEFTGKNCTIPLKETR 958
C C+NGGTC+ + N + C C S ++G+ C+ NPC ++ C+NGGTC+ + NG CKC GF C + +P + C N G C + C C GYTG+RC+ K C S C NG C L S C C FTG C+ ++E +
Sbjct: 62 CTSVGCQNGGTCVTQLNGKTYCACDSHYVGDYCEHRNPCNSMRCQNGGTCQVTFRNGRPGISCKCPLGFDESLCEI------AVPNACDHVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNL------CASSPCRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEECQ 222 HSP 6 Score: 89.3521 bits (220), Expect = 2.124e-17 Identity = 68/196 (34.69%), Postives = 86/196 (43.88%), Query Frame = 2
Query: 353 PCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCT 937
PC NG +RC C G++G C N +DC PC+NGGTC+D ++C C F G C+ + N CL+ C+NG TC N + C C GF G C + C C N G C I C C GY+G C K C S+ C NG C +N C C FTGK C+
Sbjct: 916 PCRNGASCLNVPGSYRCLCTKGYEGRDCAINTDDCASFPCQNGGTCLDGI-GDYSCLCVDGFDGKHCETDINECLSQPCQNGATCSQYVN-SYTCTCPLGFSGINCQTNDEDC------TESSCLNGGSC-IDGINGYNCSCLAGYSGANCQYKLNK-----CDSNPCLNGATCHEQNN-EYTCHCPSGFTGKQCS 1096 HSP 7 Score: 87.8113 bits (216), Expect = 6.467e-17 Identity = 105/375 (28.00%), Postives = 149/375 (39.73%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI---PLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDN--------------------------LCKASFENGIC---DQQCNTFACNYDGGDCDPWRKCY------GNDLKHCKGVFNDGVCNPECNN---------------------VDCLFDGEDCHKSSC 1264
V+ C + PC NG C++ + ++C C G+ G+ CE+NV++CI +PC N G CID+ N + C C F C + + C + C N G CE N F C C G+ G+ C + C P C + G C Y + F C+C PGYTG +C+ + C ++ C NGG C NG C CK FTG++C P R + F + K + CD LC +E C C +F C +GG C Y G D KHC+ N+ + P C N ++C + EDC +SSC
Sbjct: 676 VNVNECHSNPCNNGATCIDGIN-SYKCQCVPGFTGQHCEKNVDECISSPCANNGVCIDQVNG-YKCECPRGFYDAHCLSDVDECASNPCVNEGRCEDGIN-EFICHCPPGYTGKRCELDIDECSSNP------CQHGGTC--YDKLNAFSCQCMPGYTGQKCETNID-----DCVTNPCGNGGTCIDKVNGYK-CVCKVPFTGRDCESKMDPCASNRCKNEAKCTPSSNFLDFSCTCKLGYTGRYCDEDIDECSLSSPCRNGASCLNVPGSYRCLCTKGYEGRDCAINTDDCASFPCQ-NGGTCLDGIGDYSCLCVDGFDGKHCETDINECLSQP-CQNGATCSQYVNSYTCTCPLGFSGINCQTNDEDCTESSC 1031 HSP 8 Score: 87.0409 bits (214), Expect = 1.158e-16 Identity = 73/224 (32.59%), Postives = 105/224 (46.88%), Query Frame = 2
Query: 329 SSKLCSNRPCVNGKCVEAF--DPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCD------KKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEA 967
+ LC++ PC NG A F CSC G+ G+TC ++ +C NPCK GGTC++ S + C C + + G C + PC C+NGG C S NG+ ++CKC GF G+ C C LC N G C D + T C+C P +TG C +++ PV C NG C +GS C C + G +C+ + ++ A
Sbjct: 177 TKNLCASSPCRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEECQSNPCKYGGTCVNTHGS-YQCMCPTGYTGKDCDTKYKPCSPSPCQNGGICRS--NGLSYECKCPKGFEGKNCEQNYDDC------LGHLCQNGGTCIDGISDYT--CRCPPNFTGRFCQDDVDECAQRDHPV--------CQNGATCTNT-HGSYSCICVNGWAGLDCSNNTDDCKQAA 380 HSP 9 Score: 85.1149 bits (209), Expect = 3.803e-16 Identity = 68/186 (36.56%), Postives = 85/186 (45.70%), Query Frame = 2
Query: 389 PEFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNG-SPICECKGEFTGKNC 934
P C C G+ CE V N C C NGGTC K ++TC C + + G C+ +N C + C NG TC +L + F C C GF G+ C+ C P K C N HG + C C GYTG CD K + C C NGG+C+ NG S C+C F GKNC
Sbjct: 120 PGISCKCPLGFDESLCEIAVPNACDHVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNLCASSPCRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEECQSNPCKYGGTCVNTHG--------SYQCMCPTGYTGKDCDTKYKP-----CSPSPCQNGGICR--SNGLSYECKCPKGFEGKNC 290 HSP 10 Score: 84.3445 bits (207), Expect = 6.806e-16 Identity = 62/228 (27.19%), Postives = 112/228 (49.12%), Query Frame = 2
Query: 2276 LGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQETLRK 2953
L +++ GE+ +H+AAR + ++A + + D GRTPL +++AADA + + + LR + R TT LI A +L + M+ L+ + +N D+ G++ +HW+A NN+ E ++ + + D +D++D++PLFLAA EG+ ++ K LL F I MD P+ +A E+ ++I L+ E + +
Sbjct: 1943 LNATMDKTGETSLHLAARFARADAAKRLLDA--GADANCQDNTGRTPLHAAVAADA------MGVFQILLRNRATNLNAR--------------MHDGTTPLILAARLAIEGMVEDLITADADINAADNSGKTALHWAAAVNNT---EAVNILLMHHANRDAQDDKDETPLFLAAREGSYEACKALLDNFANREITDHMD---RLPRDVASERLHHDIVRLLDEHVPR 2142 HSP 11 Score: 84.3445 bits (207), Expect = 6.921e-16 Identity = 67/211 (31.75%), Postives = 99/211 (46.92%), Query Frame = 2
Query: 335 KLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVN---CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
K CS PC NG + + C C G++G+ CE+N +DC+ + C+NGGTCID S +TC C F G CQ + + C + C+NG TC + +G + C C G+ G C+ C K+ C C I + +C+C G TG C ++ C S+ C +C NGS C C + G +C+ + E
Sbjct: 257 KPCSPSPCQNGGICRSNGLSYECKCPKGFEGKNCEQNYDDCLGHLCQNGGTCIDGI-SDYTCRCPPNFTGRFCQDDVDECAQRDHPVCQNGATCTNT-HGSYSCICVNGWAGLDCSNNTDDC------KQAACFYGATC-IDGVGSFYCQCTKGKTGLLCH------LDDACTSNPCHADAICDTSPINGSYACSCATGYKGVDCSEDIDE 452 HSP 12 Score: 83.9593 bits (206), Expect = 9.699e-16 Identity = 74/225 (32.89%), Postives = 103/225 (45.78%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC-IDKKNSQ--FTCNCTSQFIGNLCQFE--NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKT 994
C++ C NG CV + + C+C + G+ CE N C C+NGGTC + +N + +C C F +LC+ N C +V C NGGTC+ + C C G+ GE C +N+ C P C N C + F C C PG+TGD C E C+S+ C GG C V +GS C C +TGK+C K N I ++
Sbjct: 62 CTSVGCQNGGTCVTQLNGKTYCACDSHYVGDYCEHR-NPCNSMRCQNGGTCQVTFRNGRPGISCKCPLGFDESLCEIAVPNACDHVTCLNGGTCQLKTLEEYTCACANGYTGERCETKNL-CASSP------CRNGATCTALAGSSSFTCSCPPGFTGDTCSYDIEE-----CQSNPCKYGGTC-VNTHGSYQCMCPTGYTGKDCDTKYKPCSPSPCQNGGICRS 272 HSP 13 Score: 70.8626 bits (172), Expect = 9.514e-12 Identity = 74/251 (29.48%), Postives = 102/251 (40.64%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGT-------------------------------------CIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC+N G C + + F+CSC G+ G C+ N++DC PC+N G CID NS F C C + G +CQ + N C + C+ G C+ G + C+C+ G G+ C V C P CNN C I + C+C PG+TG C+K + C S C N GVC NG CEC F +C + E +N
Sbjct: 530 CQSNPCLNDGTCHDKIN-GFKCSCALGFTGARCQINIDDCQSQPCRNRGICHDSIAGYSCECPPGYTGTSCEININDCDSNPCHRGKCIDDVNS-FKCLCDPGYTGYICQKQINECESNPCQFDGHCQD-RVGSYYCQCQAGTSGKNCEVNVNECHSNP------CNNGATC-IDGINSYKCQCVPGFTGQHCEKNVDE-----CISSPCANNGVCIDQVNGYK-CECPRGFYDAHCLSDVDECASNPCVN 764
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Match: eys (gene:FBgn0031414 transcript:FBtr0344662) HSP 1 Score: 120.168 bits (300), Expect = 7.508e-27 Identity = 67/200 (33.50%), Postives = 99/200 (49.50%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PCV G C++ + + C C G+ G C+ N ++C +PC+NGGTC+D + + C C F G+ C+ + C++ C+NGG C NG + C C+ G++G C + C + C + GEC P + C C G+ G C + EI C S C NGGVC V + C C +TG NC
Sbjct: 148 CLSNPCVFGVCIDGLNSSYSCYCIDGYTGIQCQTNWDECWSSPCQNGGTCVDGV-AYYNCTCPEGFSGSNCEENVDECMSNPCQNGGLCRDRTNG-YICTCQPGYLGSHCELDVAVCETGTGAR---CQHGGECIEGPGLEFTCDCPAGWHGRICQE------EINECASSPCQNGGVC-VDKLAAYACACPMGYTGINC 335 HSP 2 Score: 90.8929 bits (224), Expect = 6.466e-18 Identity = 53/148 (35.81%), Postives = 73/148 (49.32%), Query Frame = 2
Query: 365 GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCD 805
G+C+E EF C C GW G C+E +N+C +PC+NGG C+DK + + C C + G C+ E C + C+N C +E G+ C C + GE C Q C + P+ C N G C I T C C P TG C+
Sbjct: 274 GECIEGPGLEFTCDCPAGWHGRICQEEINECASSPCQNGGVCVDKL-AAYACACPMGYTGINCEEEILICADNPCQNNALC-LMEEGVPTCYCVPDYHGEKCEFQYDECQLGPR-----CMNGGVC-IDGVDTFSCSCPPLLTGMLCE 413
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Match: eys (gene:FBgn0031414 transcript:FBtr0344663) HSP 1 Score: 120.168 bits (300), Expect = 7.508e-27 Identity = 67/200 (33.50%), Postives = 99/200 (49.50%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PCV G C++ + + C C G+ G C+ N ++C +PC+NGGTC+D + + C C F G+ C+ + C++ C+NGG C NG + C C+ G++G C + C + C + GEC P + C C G+ G C + EI C S C NGGVC V + C C +TG NC
Sbjct: 148 CLSNPCVFGVCIDGLNSSYSCYCIDGYTGIQCQTNWDECWSSPCQNGGTCVDGV-AYYNCTCPEGFSGSNCEENVDECMSNPCQNGGLCRDRTNG-YICTCQPGYLGSHCELDVAVCETGTGAR---CQHGGECIEGPGLEFTCDCPAGWHGRICQE------EINECASSPCQNGGVC-VDKLAAYACACPMGYTGINC 335 HSP 2 Score: 90.8929 bits (224), Expect = 6.466e-18 Identity = 53/148 (35.81%), Postives = 73/148 (49.32%), Query Frame = 2
Query: 365 GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCD 805
G+C+E EF C C GW G C+E +N+C +PC+NGG C+DK + + C C + G C+ E C + C+N C +E G+ C C + GE C Q C + P+ C N G C I T C C P TG C+
Sbjct: 274 GECIEGPGLEFTCDCPAGWHGRICQEEINECASSPCQNGGVCVDKL-AAYACACPMGYTGINCEEEILICADNPCQNNALC-LMEEGVPTCYCVPDYHGEKCEFQYDECQLGPR-----CMNGGVC-IDGVDTFSCSCPPLLTGMLCE 413
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Match: LRP1 (gene:FBgn0053087 transcript:FBtr0344894) HSP 1 Score: 97.8265 bits (242), Expect = 5.538e-20 Identity = 70/219 (31.96%), Postives = 96/219 (43.84%), Query Frame = 2
Query: 338 LCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALI--NIKIP 988
+CS P + G P +C+C GW G CE ++ C Q+ C NGG+C+ + C+C F G C+ C N+ CENGG C G QC+C GF G+ C + A + C N G C I CKC GY G+ C+ C+ D+C NGG C G C C + G++C L +T N K+P
Sbjct: 4285 VCSVAPALPGS---QEPPPLKCTCTAGWSGARCETSMPAC-QSRCHNGGSCLISETEGMKCSCPKMFTGEQCEH---CRNLTCENGGICRETLTGTPQCECPDGFTGKRCEIDECA---------DFCKNGGSCVISTKGQRQCKCPSGYFGEHCESNS-------CR-DFCRNGGTCSER-GGRLSCTCPPRYIGESCESDLCKTSSPPHFCDNTKVP 4478 HSP 2 Score: 62.3882 bits (150), Expect = 3.223e-9 Identity = 47/148 (31.76%), Postives = 64/148 (43.24%), Query Frame = 2
Query: 518 CNCTSQFIGNLCQFENPCLNVNCENGGTCE-------SLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C C QF G LC+ + C+N G C S E +C C G+ G C AC + C+N G C I + C C +TG++C+ C++ C NGG+C+ G+P CEC FTGK C I
Sbjct: 4260 CICQPQFEGELCEHYR--CSGYCQNYGVCSVAPALPGSQEPPPLKCTCTAGWSGARCETSMPAC-------QSRCHNGGSCLISETEGMKCSCPKMFTGEQCEH---------CRNLTCENGGICRETLTGTPQCECPDGFTGKRCEI 4389
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Match: notch1b (notch receptor 1b [Source:ZFIN;Acc:ZDB-GENE-990415-183]) HSP 1 Score: 210.69 bits (535), Expect = 2.153e-54 Identity = 244/990 (24.65%), Postives = 399/990 (40.30%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCI--------QNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP---------------LKETRKEALINIKIPKTFN--------------EKQLIIKKTKSPSLCD-NLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTS---------------------RSNSFFSNEGLTKCSTQTKLYELDLV-------------------LMTTMQNFTKYKSEFLQKLSSSLRMVVTVFN--VTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKL----------------RSKIKTAGVWXXXXXXXXXXXXXXXGYN-FGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPI------DAGL--GDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLA--DLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C ++PC NG C++ + ++CSC G +G CE N++DC + C N G C+D+ + C C ++G C+ + N CL+ C +C L+N ++C+CR G+ G+ C V K + C N G C + N CKC PG+TG C+ C S C NGG C V + SP C C FTG C P + +E + P FN Q I K C+ CK N ICD CN +AC++DGGDC DPW+ C C FN+G C+ +C+N CL+DG DC + + + C + + + CD+ CN+ +C +DG DC R+NSF L++ ++ D + ++ + S+ L + +S+ +V E+ ++ L ++ QC +CF S + FL A G+ L +P+ + V + I S + P+Y ++ LL F + R + G+L R + V + S ++ N +G + K F+ E Q ++ + QP Q H D SI + E N + + DG P+ GL G+ ++ D YQ ++L + GE+ +H+AAR + + A + + D GRTPL +++AADA + Q+LI + +++ + TT LI A +L + M+ L++ + VN +D G+S +HW+A + + M + + A D+++N++++PLFLAA EG+ ++ K LL +F I MD P+ IA+++ ++I LI E
Sbjct: 1167 CLSQPCQNGGTCIDLIN-TYKCSCPRGTQGVHCEINIDDCTPFTDPITHEPKCFNQGRCVDRVGG-YHCICPPGYVGERCEGDVNECLSNPCGTH-SCIQLKNN-YRCECRTGYTGQHCD------KVFDGCKGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAH-----ACGSLQCKNGGTC-VSGHKSPKCLCTPAFTGPECQDPSGGHCTTNPCYNGGTCEYITEEPYYHCICPTNFNGLFCHILDWSFPGGTGQDITPAPKVSVSCEIEQCKVKKGNKICDSACNNYACDWDGGDCSLNFNDPWKNCSA--ALQCWRYFNNGKCDEQCHNTGCLYDGFDCQRVEAQCNPLYDQYCKDHFADGYCDQGCNNAECEWDGLDCANDTPEKLAAGLLVVVVHIHPDQLRNNSFGFLRELSRVLHTNVVFRRDSKGQEMIYPYYGNEQELKKHNIKRSLDGWNDASSDVLSSMKNSIYNIVVEGGRKRRELEKIQVKGSVVYLEIDNRQCYQQTSECFQSANDAAAFLGALASSGS-LKMPYVIEAVTSEIDGPSPVELYPVYVVLAGLALLAFVAIGMVASRKRRREHGQLWFPEGFKTSEPSKKKRREPVGEDSVGLRPLKNCSDISLMDDNQNEWGEEEQSDSKRFRSEEQ---AMLDLDDQPDHRQWTQQHLDAADLRIPSIAPTPPQGEIEN--------DCMDVNARGPDGFTPLMIASCSGGGLETGNSEEEEDASANVINDFIYQGANLH---NQTDRTGETALHLAARYARSDAAKRLLEASADANIQ--DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDARMH-------------------DGTTPLILAARLAVEGMVEELINCHADVNAIDDFGKSALHWAAA-----VNNVDAAMVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLEHFANREITDHMD---RLPRDIAQDRMHHDIVRLIDE 2093 HSP 2 Score: 93.5893 bits (231), Expect = 1.521e-18 Identity = 122/474 (25.74%), Postives = 160/474 (33.76%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGW------------------------------------------------KGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVI--PKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDK------------------KKELPVEI--------------GCKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQ----QCNTFACNYDGGDC-----DPWRKCY---------------------GND------------LKHCKGVFNDGVCNPECNNVDCLFDGEDCH-------KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCH 1357
C PC NG + C C GW G CEE V++CI NPC+NG TC D ++C C + G C E N CL+ C+NGGTC L N ++C C G G C + C P C N G C + C C PGY G+RC+ K E GCK C NGG C V N +P IC+C FTG C E A +++ + KSP LC +F C C T C Y+GG C +P+ C G D ++ CK + +C+ CNN C +DG DC K+ +C + N CDE+C++ C +DG DC
Sbjct: 1043 CKPSPCKNGGICRQSGTRYSCQCQTGWTGLYCDVPSVSCEVAAKQQGVDVVRLCRNSGQCLDAGNTHYCHCQAGYTGSYCEEQVDECIPNPCQNGATCTDYLGG-YSCECVPGYHGVNCSDEINECLSQPCQNGGTCIDLIN-TYKCSCPRGTQGVHCEINIDDCTPFTDPITHEPKCFNQGRC-VDRVGGYHCICPPGYVGERCEGDVNECLSNPCGTHSCIQLKNNYRCECRTGYTGQHCDKVFDGCKGKPCRNGGTCAVASN-TPHGFICKCPPGFTGSTC-----EYDAHACGSLQC----KNGGTCVSGHKSPKC---LCTPAFTGPECQDPSGGHCTTNPC-YNGGTCEYITEEPYYHCICPTNFNGLFCHILDWSFPGGTGQDITPAPKVSVSCEIEQCKVKKGNKICDSACNNYACDWDGGDCSLNFNDPWKNCSAALQCWRYFNNGKCDEQCHNTGCLYDGFDCQ 1499 HSP 3 Score: 92.8189 bits (229), Expect = 2.151e-18 Identity = 107/374 (28.61%), Postives = 150/374 (40.11%), Query Frame = 2
Query: 317 LVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN--------------IKIPKTFNEKQLIIKK-TKSP----SLCDNL-------CKASF------------------ENGICDQQCNTFAC----NYDGGDCDP-WRKCYGNDLKH---CKGVFNDGVCN--PECNNVDCLFDGEDCHKSSC 1264
L ++ C ++PC NG + + + C C G G CE N++DC NPC + G CIDK N + C C + G +C + C C NGGTC NG F C CR G+ C Q C P I HG C+ N C CD G++G CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N +P T ++ I + K+P ++C N CKA + G C N FAC + GG C+ +C N K+ C N C P + + C + DC +SSC
Sbjct: 619 LCEININECLSQPCQNGGTCQDRENAYLCVCPKGTAGANCEINLDDCQSNPC-DFGRCIDKING-YECACEPGYTGKMCNINIDECAINPCHNGGTCVDGVNG-FTCLCREGYHDTTCQSQLNECLSNPCI----------HGHCEDKVN-GYNCICDSGWSGVNCDINNNE-----CESNPCMNGGTCKDMTSGY-VCTCRAGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGQTCEVDINECVKNPCRNDAICQNSIGSYKCSCKAGYTGRNCETDIDDCKPNPCSNGGFCKDAVNAFACTCLPGFRGGRCEEDINECESNPCKNGANCTDCVNSYTCTCPPGFSGIHCENNTPDCTESSC 972 HSP 4 Score: 92.4337 bits (228), Expect = 3.630e-18 Identity = 79/253 (31.23%), Postives = 105/253 (41.50%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF------ENPC------------------------LNVN--------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC G C + F C C G+ G CE N+N+C+ PC+NGGTC D++N+ + C C G C+ NPC N+N C NGGTC NG F C CR G+ C Q C P I HG C+ N C CD G++G CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 590 CLSNPCHYGTCKDGL-ASFTCVCRAGFMGRLCEININECLSQPCQNGGTCQDRENA-YLCVCPKGTAGANCEINLDDCQSNPCDFGRCIDKINGYECACEPGYTGKMCNINIDECAINPCHNGGTCVDGVNG-FTCLCREGYHDTTCQSQLNECLSNPCI----------HGHCEDKVN-GYNCICDSGWSGVNCDINNNE-----CESNPCMNGGTCKDMTSGY-VCTCRAGFSGPNCQTNINECASNPCLN 822 HSP 5 Score: 86.2705 bits (212), Expect = 2.576e-16 Identity = 74/225 (32.89%), Postives = 102/225 (45.33%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL-----CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC--IDKKNS-QFTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
M++F + ++VI + L CS + G C D C C + G C+ N C Q+PC+NGG C I N F CNC+ + LC N CL C NGGTCE ++CKC G+ G+ C Q C P C N G+C + + C C P ++G C + +I C NGGVC+ G+ C C E+TGK+C
Sbjct: 1 MHLFFVKLIVVISLNTLTQGLECSEKCQNGGTCEPTADGRGECKCLDLYAGPACQFR-NPCFQSPCRNGGVCRLITSANKVDFVCNCSLGYTDRLCLTPTNNVCLGAPCRNGGTCELTSIHNYRCKCPPGWSGKTCQ-QADPCASNP------CANGGQCSPF-DSDFLCHCTPYFSGQTCKQDVNECAQI---PSPCKNGGVCEN-GVGTYHCNCPAEYTGKHC 212 HSP 6 Score: 80.8777 bits (198), Expect = 1.020e-14 Identity = 74/273 (27.11%), Postives = 105/273 (38.46%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAV-QNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACN----YDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSC 1264
C+NGGTC + + C C + G CQF NPC C NGG C + + F C C G+ C N C P C N G C++ CKC PG++G C + C S+ C NGG C D+ +C C F+G+ C KQ + + + PS C N G+C+ T+ CN Y G KHC+ ++ +P + C+ GE ++ SC
Sbjct: 27 CQNGGTCEPTADGRGECKCLDLYAGPACQFRNPCFQSPCRNGGVCRLITSANKVDFVCNCSLGYTDRLCLTPTNNVCLGAP------CRNGGTCELTSIHNYRCKCPPGWSGKTCQQADP------CASNPCANGGQCSPFDSDF-LCHCTPYFSGQTC-----------------------KQDVNECAQIPSPCKN-------GGVCENGVGTYHCNCPAEYTG--------------KHCESLYQPCNPSPCLHGGTCVQKGETSYECSC 242 HSP 7 Score: 77.0258 bits (188), Expect = 1.707e-13 Identity = 65/207 (31.40%), Postives = 99/207 (47.83%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQ--NPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C++ PC NG FD +F C C + G+TC+++VN+C Q +PCKNGG C + + + CNC +++ G C+ PC C +GGTC ++C C G EF + R+ N+ Y M +F G++G C++ + C C NGG C V + C+CK E+TG+ CT + E
Sbjct: 141 CASNPCANGGQCSPFDSDFLCHCTPYFSGQTCKQDVNECAQIPSPCKNGGVCENGVGT-YHCNCPAEYTGKHCESLYQPCNPSPCLHGGTCVQKGETSYECSCLPGRQ-EFVLIM-----------RKCLND------YFLMLVF----IGFSGQNCEENID-----DCPDHRCLNGGTC-VDGVNTYNCQCKPEWTGQFCTEDVNE 318 HSP 8 Score: 76.2554 bits (186), Expect = 2.928e-13 Identity = 65/232 (28.02%), Postives = 95/232 (40.95%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSD----------YC-----FNGGVCKV----------LDNGSPI-------CECKGEFTGKNCTIPLKE 952
C NG + C C +GW G+ C EN++DC C G TC D+ S F C C G LC ++ C++ C+ G C++ NG C C G++G C C + C + G+C I + CKC GY G RC+ + C++D +C + G C++ L+NG I CEC F+G C + E
Sbjct: 326 CQNGGTCLNTQGGYNCVCVNGWTGDDCSENIDDCADAACHTGATCHDRVAS-FLCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPLGYVGPACDQDVDECSL----GANPCEHAGKC-INTKGSFQCKCLQGYVGARCELDINECLSTPCQNDATCLDQIGGFHCICMPGYEGVFCQINTDECASMPCLNNGKCIDKINNYQCECPTGFSGSQCQFDIDE 551 HSP 9 Score: 71.633 bits (174), Expect = 7.465e-12 Identity = 70/263 (26.62%), Postives = 109/263 (41.44%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSC-----------------------WHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC--LNVNCENGGTCESLENGMFQCKCRYGFIGEFCA-----VQNIACPV--------------IPKKKREL------------CNNHGECDIYP-NMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C+ PC++G CV+ + + CSC + G+ G+ CEEN++DC + C NGGTC+D N+ + C C ++ G C + N C + +C+NGGTC + + G + C C G+ G+ C+ + AC P + L C CD P N C C GY G CD+ + E ++ C + G C + GS C+C + G C + + E
Sbjct: 219 CNPSPCLHGGTCVQKGETSYECSCLPGRQEFVLIMRKCLNDYFLMLVFIGFSGQNCEENIDDCPDHRCLNGGTCVDGVNT-YNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGG-YNCVCVNGWTGDDCSENIDDCADAACHTGATCHDRVASFLCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPLGYVGPACDQDVD---ECSLGANPCEHAGKC-INTKGSFQCKCLQGYVGARCELDINE 475 HSP 10 Score: 68.9366 bits (167), Expect = 3.964e-11 Identity = 60/194 (30.93%), Postives = 77/194 (39.69%), Query Frame = 2
Query: 341 CSNRPCVNGKC----VEAFDPEFRCSCWHGWKGETCEENVND-CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICEC 907
C PC NG A +F C+C G+ C N+ C+ PC+NGGTC + C C + G CQ +PC + C NGG C ++ F C C F G+ C C IP C N G C+ T C C YTG C+ + C C +GG C S C C
Sbjct: 60 CFQSPCRNGGVCRLITSANKVDFVCNCSLGYTDRLCLTPTNNVCLGAPCRNGGTCELTSIHNYRCKCPPGWSGKTCQQADPCASNPCANGGQCSPFDSD-FLCHCTPYFSGQTCKQDVNECAQIPSP----CKNGGVCENGVG-TYHCNCPAEYTGKHCESLYQP-----CNPSPCLHGGTCVQKGETSYECSC 242
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Match: notch1b (notch receptor 1b [Source:ZFIN;Acc:ZDB-GENE-990415-183]) HSP 1 Score: 209.92 bits (533), Expect = 2.962e-54 Identity = 244/990 (24.65%), Postives = 399/990 (40.30%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCI--------QNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP---------------LKETRKEALINIKIPKTFN--------------EKQLIIKKTKSPSLCD-NLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTS---------------------RSNSFFSNEGLTKCSTQTKLYELDLV-------------------LMTTMQNFTKYKSEFLQKLSSSLRMVVTVFN--VTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKL----------------RSKIKTAGVWXXXXXXXXXXXXXXXGYN-FGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPI------DAGL--GDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLA--DLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C ++PC NG C++ + ++CSC G +G CE N++DC + C N G C+D+ + C C ++G C+ + N CL+ C +C L+N ++C+CR G+ G+ C V K + C N G C + N CKC PG+TG C+ C S C NGG C V + SP C C FTG C P + +E + P FN Q I K C+ CK N ICD CN +AC++DGGDC DPW+ C C FN+G C+ +C+N CL+DG DC + + + C + + + CD+ CN+ +C +DG DC R+NSF L++ ++ D + ++ + S+ L + +S+ +V E+ ++ L ++ QC +CF S + FL A G+ L +P+ + V + I S + P+Y ++ LL F + R + G+L R + V + S ++ N +G + K F+ E Q ++ + QP Q H D SI + E N + + DG P+ GL G+ ++ D YQ ++L + GE+ +H+AAR + + A + + D GRTPL +++AADA + Q+LI + +++ + TT LI A +L + M+ L++ + VN +D G+S +HW+A + + M + + A D+++N++++PLFLAA EG+ ++ K LL +F I MD P+ IA+++ ++I LI E
Sbjct: 1138 CLSQPCQNGGTCIDLIN-TYKCSCPRGTQGVHCEINIDDCTPFTDPITHEPKCFNQGRCVDRVGG-YHCICPPGYVGERCEGDVNECLSNPCGTH-SCIQLKNN-YRCECRTGYTGQHCDK------VFDGCKGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAH-----ACGSLQCKNGGTC-VSGHKSPKCLCTPAFTGPECQDPSGGHCTTNPCYNGGTCEYITEEPYYHCICPTNFNGLFCHILDWSFPGGTGQDITPAPKVSVSCEIEQCKVKKGNKICDSACNNYACDWDGGDCSLNFNDPWKNCSA--ALQCWRYFNNGKCDEQCHNTGCLYDGFDCQRVEAQCNPLYDQYCKDHFADGYCDQGCNNAECEWDGLDCANDTPEKLAAGLLVVVVHIHPDQLRNNSFGFLRELSRVLHTNVVFRRDSKGQEMIYPYYGNEQELKKHNIKRSLDGWNDASSDVLSSMKNSIYNIVVEGGRKRRELEKIQVKGSVVYLEIDNRQCYQQTSECFQSANDAAAFLGALASSGS-LKMPYVIEAVTSEIDGPSPVELYPVYVVLAGLALLAFVAIGMVASRKRRREHGQLWFPEGFKTSEPSKKKRREPVGEDSVGLRPLKNCSDISLMDDNQNEWGEEEQSDSKRFRSEEQ---AMLDLDDQPDHRQWTQQHLDAADLRIPSIAPTPPQGEIEN--------DCMDVNARGPDGFTPLMIASCSGGGLETGNSEEEEDASANVINDFIYQGANLH---NQTDRTGETALHLAARYARSDAAKRLLEASADANIQ--DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDARMH-------------------DGTTPLILAARLAVEGMVEELINCHADVNAIDDFGKSALHWAAA-----VNNVDAAMVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLEHFANREITDHMD---RLPRDIAQDRMHHDIVRLIDE 2064 HSP 2 Score: 94.3597 bits (233), Expect = 7.791e-19 Identity = 70/219 (31.96%), Postives = 98/219 (44.75%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+++ C + PC+NG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ PC + C+NGG C ES + F C C G+ G+ C V C P + +C N + C C GYTG C+ + CK + C NGG CK N C C F G C + E N
Sbjct: 703 INNNECESNPCMNGGTCKDMTSGYVCTCRAGFSGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCLLPYTGENCETLLAPCGSKPCKNGGVCKESEDYESFSCVCPAGWQGQTCEVDINECVKNPCRNDAICQNS-------IGSYKCSCKAGYTGRNCETDID-----DCKPNPCSNGGFCKDAVNAF-ACTCLPGFRGGRCEEDINECESNPCKN 907 HSP 3 Score: 92.8189 bits (229), Expect = 2.296e-18 Identity = 122/474 (25.74%), Postives = 160/474 (33.76%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGW------------------------------------------------KGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVI--PKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDK------------------KKELPVEI--------------GCKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQ----QCNTFACNYDGGDC-----DPWRKCY---------------------GND------------LKHCKGVFNDGVCNPECNNVDCLFDGEDCH-------KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCH 1357
C PC NG + C C GW G CEE V++CI NPC+NG TC D ++C C + G C E N CL+ C+NGGTC L N ++C C G G C + C P C N G C + C C PGY G+RC+ K E GCK C NGG C V N +P IC+C FTG C E A +++ + KSP LC +F C C T C Y+GG C +P+ C G D ++ CK + +C+ CNN C +DG DC K+ +C + N CDE+C++ C +DG DC
Sbjct: 1014 CKPSPCKNGGICRQSGTRYSCQCQTGWTGLYCDVPSVSCEVAAKQQGVDVVRLCRNSGQCLDAGNTHYCHCQAGYTGSYCEEQVDECIPNPCQNGATCTDYLGG-YSCECVPGYHGVNCSDEINECLSQPCQNGGTCIDLIN-TYKCSCPRGTQGVHCEINIDDCTPFTDPITHEPKCFNQGRC-VDRVGGYHCICPPGYVGERCEGDVNECLSNPCGTHSCIQLKNNYRCECRTGYTGQHCDKVFDGCKGKPCRNGGTCAVASN-TPHGFICKCPPGFTGSTC-----EYDAHACGSLQC----KNGGTCVSGHKSPKC---LCTPAFTGPECQDPSGGHCTTNPC-YNGGTCEYITEEPYYHCICPTNFNGLFCHILDWSFPGGTGQDITPAPKVSVSCEIEQCKVKKGNKICDSACNNYACDWDGGDCSLNFNDPWKNCSAALQCWRYFNNGKCDEQCHNTGCLYDGFDCQ 1470 HSP 4 Score: 92.0485 bits (227), Expect = 4.705e-18 Identity = 79/253 (31.23%), Postives = 105/253 (41.50%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF------ENPC------------------------LNVN--------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC G C + F C C G+ G CE N+N+C+ PC+NGGTC D++N+ + C C G C+ NPC N+N C NGGTC NG F C CR G+ C Q C P I HG C+ N C CD G++G CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 521 CLSNPCHYGTCKDGL-ASFTCVCRAGFMGRLCEININECLSQPCQNGGTCQDRENA-YLCVCPKGTAGANCEINLDDCQSNPCDFGRCIDKINGYECACEPGYTGKMCNINIDECAINPCHNGGTCVDGVNG-FTCLCREGYHDTTCQSQLNECLSNPCI----------HGHCEDKVN-GYNCICDSGWSGVNCDINNNE-----CESNPCMNGGTCKDMTSGY-VCTCRAGFSGPNCQTNINECASNPCLN 753 HSP 5 Score: 84.7297 bits (208), Expect = 6.726e-16 Identity = 83/314 (26.43%), Postives = 124/314 (39.49%), Query Frame = 2
Query: 314 LLVIVSSKLCSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKN------------------------------------SQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCD---NLCKAS--FENGICDQQCNTFACNYDGG 1126
+ +++ C++ PC+N GKC++ + ++C C G+ G C+ ++++C PCKNG C+D N + FTC C + F+G LC+ N CL+ C+NGGTC+ EN + C C G G C + C P + G C I C C+PGYTG C+ + C + C NGG C NG C C+ + C L E I+ N I S CD N C+++ G C + + C G
Sbjct: 436 VFCQINTDECASMPCLNNGKCIDKIN-NYQCECPTGFSGSQCQFDIDECASTPCKNGAKCMDGPNMYTCQCTEGYTGQHCETDVDECLSNPCHYGTCKDGLASFTCVCRAGFMGRLCEININECLSQPCQNGGTCQDREN-AYLCVCPKGTAGANCEINLDDCQSNPC-------DFGRC-IDKINGYECACEPGYTGKMCNINIDE-----CAINPCHNGGTCVDGVNGF-TCLCREGYHDTTCQSQLNECLSNPCIHGHCEDKVNGYNCICDSGWSGVNCDINNNECESNPCMNGGTCKDMTSGYVCTCRAG 733 HSP 6 Score: 83.5741 bits (205), Expect = 1.538e-15 Identity = 70/240 (29.17%), Postives = 108/240 (45.00%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC--LNVNCENGGTCESLENGMFQCKCRYGFIGEFCA-----VQNIACPV--------------IPKKKREL------------CNNHGECDIYP-NMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C+ PC++G CV+ + + CSC G+ G+ CEEN++DC + C NGGTC+D N+ + C C ++ G C + N C + +C+NGGTC + + G + C C G+ G+ C+ + AC P + L C CD P N C C GY G CD+ + E ++ C + G C + GS C+C + G C + + E
Sbjct: 173 CNPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNT-YNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGG-YNCVCVNGWTGDDCSENIDDCADAACHTGATCHDRVASFLCECPHGRTGLLCHLDDACISNPCQKGSNCDTNPVNGKAICTCPLGYVGPACDQDVD---ECSLGANPCEHAGKC-INTKGSFQCKCLQGYVGARCELDINE 406 HSP 7 Score: 77.0258 bits (188), Expect = 1.747e-13 Identity = 60/167 (35.93%), Postives = 79/167 (47.31%), Query Frame = 2
Query: 449 NDCIQNPCKNGGTC--IDKKNS-QFTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
N C Q+PC+NGG C I N F CNC+ + LC N CL C NGGTCE ++CKC G+ G+ C Q C P C N G+C + + C C P ++G C + +I C NGGVC+ G+ C C E+TGK+C
Sbjct: 12 NPCFQSPCRNGGVCRLITSANKVDFVCNCSLGYTDRLCLTPTNNVCLGAPCRNGGTCELTSIHNYRCKCPPGWSGKTCQ-QADPCASNP------CANGGQCSPF-DSDFLCHCTPYFSGQTCKQDVNECAQI---PSPCKNGGVCEN-GVGTYHCNCPAEYTGKHC 166 HSP 8 Score: 76.2554 bits (186), Expect = 2.407e-13 Identity = 64/203 (31.53%), Postives = 83/203 (40.89%), Query Frame = 2
Query: 341 CSNRPCVNGKC----VEAFDPEFRCSCWHGWKGETCEENVND-CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C PC NG A +F C+C G+ C N+ C+ PC+NGGTC + C C + G CQ +PC + C NGG C ++ F C C F G+ C C IP C N G C+ T C C YTG C+ + C C +GG C S C C F+G+NC
Sbjct: 14 CFQSPCRNGGVCRLITSANKVDFVCNCSLGYTDRLCLTPTNNVCLGAPCRNGGTCELTSIHNYRCKCPPGWSGKTCQQADPCASNPCANGGQCSPFDSD-FLCHCTPYFSGQTCKQDVNECAQIPSP----CKNGGVCENGVG-TYHCNCPAEYTGKHCESLYQP-----CNPSPCLHGGTCVQKGETSYECSCLPGFSGQNC 205 HSP 9 Score: 75.0998 bits (183), Expect = 6.037e-13 Identity = 68/241 (28.22%), Postives = 98/241 (40.66%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQ--NPCKNGG--------------------------------------TCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C++ PC NG FD +F C C + G+TC+++VN+C Q +PCKNGG TC+ K + + C+C F G C+ + C + C NGGTC N + C+C+ + G+FC C ++P C N G C + C C G+TGD C + + C C G C S +CEC TG C +
Sbjct: 95 CASNPCANGGQCSPFDSDFLCHCTPYFSGQTCKQDVNECAQIPSPCKNGGVCENGVGTYHCNCPAEYTGKHCESLYQPCNPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVN-TYNCQCKPEWTGQFCTEDVNECDLMPNS----CQNGGTC-LNTQGGYNCVCVNGWTGDDCSENID-----DCADAACHTGATCHDR-VASFLCECPHGRTGLLCHL 323 HSP 10 Score: 70.4774 bits (171), Expect = 1.463e-11 Identity = 72/262 (27.48%), Postives = 103/262 (39.31%), Query Frame = 2
Query: 533 QFIGNLCQFENPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAV-QNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACN----YDGGDCDP-WRKCYGNDLKHCKGVFNDGVCNPECNNVDCL--FDGEDCHKS--SCKFHKC 1279
Q+ G CQF NPC C NGG C + + F C C G+ C N C P C N G C++ CKC PG++G C + C S+ C NGG C D+ +C C F+G+ C KQ + + + PS C N G+C+ T+ CN Y G C+ ++ C + H G + EC+ CL F G++C ++ C H+C
Sbjct: 2 QYAGPACQFRNPCFQSPCRNGGVCRLITSANKVDFVCNCSLGYTDRLCLTPTNNVCLGAP------CRNGGTCELTSIHNYRCKCPPGWSGKTCQQADP------CASNPCANGGQCSPFDSDF-LCHCTPYFSGQTC-----------------------KQDVNECAQIPSPCKN-------GGVCENGVGTYHCNCPAEYTGKHCESLYQPCNPSPCLHGGTCVQKGETSYECS---CLPGFSGQNCEENIDDCPDHRC 217
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Match: notch1a (notch receptor 1a [Source:NCBI gene;Acc:30718]) HSP 1 Score: 157.532 bits (397), Expect = 3.501e-38 Identity = 145/599 (24.21%), Postives = 222/599 (37.06%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS---------------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL---------------KETRKEALINIKIPKTFN--------------EKQLIIKKTKSPSLCD-NLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGL---------TKCSTQTKLYELDLVLMTTM-------------------QNFTKYK-------SEFLQKLSSSLRMVVTVFNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIY 1762
C PC NG + + C C G+ G C + +N+C+ PC+NGGTCID N+ + C C + F+G C+ + N CL+ C+ G+ C L N F+C+CR G+ G+ C C P C N G C + N CKC PGY+G C+ + C S C NG C V + SP C C F+G C + + P FN + + I + C+ C+ N ICD QCN AC +DGGDC DPW+ C C FNDG C+ +C CL+DG DC + + + C + Y + CD+ CN+ +C +DG DC + + + + L EL +L T + +K+K + +Q+ SL + E++ ++ L ++ QC +CF S ++ FL A GN L++P+ + V + + P++
Sbjct: 365 CQPNPCQNGATCTDYLGGYSCECVPGYHGMNCSKEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEIDIDDCSPSVDPLTGEPRCFNGGRCVDRVGGYGCVCPAGFVGERCEGDVNECLSDPCDPSGSYNCVQLIND-FRCECRTGYTGKRCETVFNGCKDTP------CKNGGTCAVASNTKHGYICKCQPGYSGSSCEYDSQ-----SCGSLRCRNGATC-VSGHLSPRCLCAPGFSGHECQTRMDSPCLVNPCYNGGTCQPISDAPFYRCSCPANFNGLLCHILDYSFSGGQGRDIAPPVEVEIRCEIAQCEGRGGNAICDTQCNNHACGWDGGDCSLNFDDPWQNCSA--ALQCWRYFNDGKCDEQCATAGCLYDGFDCQRLEGQCNPLYDQYCRDHYADGHCDQGCNNAECEWDGLDCADDVPQKLAVGSLVLVVHIPPDELRNRSSSFLRELSSLLHTNVVFRRDANGEALIFPYYGSEHELSKHKRSDWTDPGQLMQRARRSLTSFLKPRTRRELDHMEVKGSIVYLEIDNRQCFQQSDECFQSATDVAAFLGALASSGN-LNVPYIIEAVTSEGGPPKTGEMYPMF 947 HSP 2 Score: 110.153 bits (274), Expect = 1.135e-23 Identity = 80/207 (38.65%), Postives = 100/207 (48.31%), Query Frame = 2
Query: 341 CSNRPCVNGK-CVEAFD-PEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
CS RPC NG C E+ D F C+C GW+G+TCE ++N+C++NPC NGG C + + F C C F G LC+ + + C C NGG C+ NG F C C GF GE CA C P C N G C N + C C G++G C+ C CFNGG C V S C C FTG C + E
Sbjct: 49 CSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVCENLRGG-FQCRCNPGFTGALCENDIDDCEPNPCSNGGVCQDRVNG-FVCVCLAGFRGERCAEDIDECVSAP------CRNGGNCTDCVN-SYTCSCPAGFSGINCEINTP-----DCTESSCFNGGTC-VDGISSFSCVCLPGFTGNYCQHDVNE 240 HSP 3 Score: 107.071 bits (266), Expect = 1.026e-22 Identity = 76/215 (35.35%), Postives = 105/215 (48.84%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQ-FTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C++ PC+N G C++ F+C+C + GE CE + C PCKNGG C + ++ Q F+CNC + + G C+ + N C+ C NGG CE+L G FQC+C GF G C C P C+N G C N C C G+ G+RC + + C S C NGG C N S C C F+G NC I + + + N
Sbjct: 11 CASNPCLNQGSCIDDV-AGFKCNCMLPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVDINECVRNPCTNGGVCENLRGG-FQCRCNPGFTGALCENDIDDCEPNP------CSNGGVCQDRVN-GFVCVCLAGFRGERCAEDIDE-----CVSAPCRNGGNCTDCVN-SYTCSCPAGFSGINCEINTPDCTESSCFN 210 HSP 4 Score: 97.8265 bits (242), Expect = 5.865e-20 Identity = 69/199 (34.67%), Postives = 89/199 (44.72%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C PC NG E F+C C G+ G CE +++DC NPC NGG C D+ N F C C + F G C + + C++ C NGG C N + C C GF G C + P C N G C + + C C PG+TG+ C C S C NGG C+ G+ C C +TG NC
Sbjct: 89 CVRNPCTNGGVCENLRGGFQCRCNPGFTGALCENDIDDCEPNPCSNGGVCQDRVNG-FVCVCLAGFRGERCAEDIDECVSAPCRNGGNCTDCVNS-YTCSCPAGFSGINCEIN------TPDCTESSCFNGGTC-VDGISSFSCVCLPGFTGNYCQHDVNE-----CDSRPCQNGGSCQD-GYGTYKCTCPHGYTGLNC 272 HSP 5 Score: 90.8929 bits (224), Expect = 7.998e-18 Identity = 63/178 (35.39%), Postives = 88/178 (49.44%), Query Frame = 2
Query: 425 GETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
G C+ N+N+C NPC N G+CID + F CNC + G +C+ PC C+NGG C ES + F C C G+ G+ C V I + R C N G C+ C+C+PG+TG C+ + C+ + C NGGVC+ NG +C C F G+ C + E
Sbjct: 1 GPNCQMNINECASNPCLNQGSCIDDV-AGFKCNCMLPYTGEVCENVLAPCSPRPCKNGGVCRESEDFQSFSCNCPAGWQGQTCEVD------INECVRNPCTNGGVCENL-RGGFQCRCNPGFTGALCENDID-----DCEPNPCSNGGVCQDRVNGF-VCVCLAGFRGERCAEDIDE 164 HSP 6 Score: 89.3521 bits (220), Expect = 2.658e-17 Identity = 70/238 (29.41%), Postives = 100/238 (42.02%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-----------ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIK 1021
C +RPC NG + ++C+C HG+ G C+ V C +PCKNGG+C ++ + FTC C S + G C + + V C + G C N C+C+ G+ G +C Q C P C N C Y C+C PGY G C K+ C S C NGG C L N + C C G +C I + + P+ FN + + +
Sbjct: 241 CDSRPCQNGGSCQDGYGTYKCTCPHGYTGLNCQSLVRWCDSSPCKNGGSCW-QQGASFTCQCASGWTGIYCDVPSVSCEVAARQQGVSVAVLCRHAGQCVDAGNTHL-CRCQAGYTGSYCQEQVDECQPNP------CQNGATCTDYLG-GYSCECVPGYHGMNCSKEINE-----CLSQPCQNGGTCIDLVN-TYKCSCPRGTQGVHCEIDIDDCSPSVDPLTGEPRCFNGGRCVDR 463 HSP 7 Score: 77.411 bits (189), Expect = 1.090e-13 Identity = 61/222 (27.48%), Postives = 107/222 (48.20%), Query Frame = 2
Query: 2276 LGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
L + GE+ +H+AAR + + + + + D GRTPL +++AADA + Q+LI + +++ + TT LI A +L + M+ L++ + N +D G+S +HW+A NN L + DL++N++++PLFLAA EG+ ++ K LL + I D P+ IA E+ ++I L++E
Sbjct: 1126 LHNQTDRTGETALHLAARYARSDAAKRLLESCADANVQ--DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDARMHD-------------------GTTPLILATRLAVEGMVEELINCHADPNAVDDSGKSALHWAAAVNNVDAAVVLLKNGANK---DLQNNKEETPLFLAAREGSYETAKVLLDHLANRDIA-DHLDQLPRDIAHERMHHDIVRLLEE 1321
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Match: notch3 (notch receptor 3 [Source:ZFIN;Acc:ZDB-GENE-000329-5]) HSP 1 Score: 155.221 bits (391), Expect = 2.270e-37 Identity = 143/552 (25.91%), Postives = 224/552 (40.58%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVN-------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP--ICECKGEFTGKN-----------------CTIPLKETRKEALINIKIP------------KTFNEKQLIIKKTKSPSL---CDNL------------------------CKASFENGICDQQCNTFACNYDGGDC----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDC---HKSSCKFHK--CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTVFNV-------------------TEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARV 1714
C +PC+NG ++ F C C G++G CE VN+C +PC+NGGTCID + C+C +G LC+ E+ C + C+N GTC G ++C C GF GE C C P +N +C PN C C PG+TG C + + C+S C NGGVC + + P C C+ + G N CT+ + R + P K + L ++T P C N C + +G+CD++CN+ C +DGGDC +PW +C C +FN+ C+ CNN +CLFD DC K ++ C++ Y + +CD+ CN+ +CG+DG DC + L +V++ + + ++ FLQKLS+ LR + F + E+N ++ L ++ C CF + + + +L A + +L P+ + V
Sbjct: 1054 CEEKPCLNGATCRSYMGGFTCDCMPGYEGNNCEREVNECQSHPCQNGGTCIDLV-GHYICSCPPGTLGVLCEINEDDCATPSWPRGMPKCQNNGTCVDRVGG-YRCNCPPGFTGERCEGDINECLSNPCNP----SNSLDCIQLPN-DYQCVCKPGFTGRGCQSRFSV-----CESQPCKNGGVCSLSGSSPPGYSCTCQLGYAGSNCERSMNCKELPCYNGGSCTLTTRGARCTCIQGFGGPLCQHRSNDGCSSKPCHNGGLCTEETSYPFFHCQCTNGWKGKRCEQKTGSSAPLPSPCPIADCFSKANDGVCDKECNSLDCRWDGGDCSLAVNPWARCAD---PRCWRLFNNSQCDEFCNNAECLFDNFDCINKEKVCNPIYEAYCTDHYADGLCDQGCNTEECGWDGLDCARKIPEDLAED-------------MLVIVVLLPPEELLRTQTAFLQKLSAILRTTLR-FRLDRNGDYMIRPYTGRETRIKRELNPQEVIGSIVYLEIDNRLCSQGSDDCFRNADSAAEYLGA-LSAREMLRFPYPIKEV 1575 HSP 2 Score: 118.627 bits (296), Expect = 2.911e-26 Identity = 80/199 (40.20%), Postives = 104/199 (52.26%), Query Frame = 2
Query: 353 PCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENP-CLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
PC+NG C + + FRCSC G+ G C +N+C PCKNGGTC D NS +TC C F G LC+ P C +C NGGTC NG F+C CR GF G++C + C P +C + E + C C GYTG RC + PV+ S+ C NGG C+ D S C+C G ++G+ C IP
Sbjct: 819 PCLNGGSCTDGVN-SFRCSCLPGFTGARCATELNECQSVPCKNGGTCTDYVNS-YTCTCKPGFTGLLCETNVPDCTESSCFNGGTCTDGING-FKCTCRTGFTGDYCQYEVNECDSQPCLNGGICQDAME-------SYRCSCPKGYTGPRC----QYPVDWCRPSNPCKNGGRCRQKD-ASFTCDCLGGWSGRYCDIP 1002 HSP 3 Score: 101.679 bits (252), Expect = 4.468e-21 Identity = 74/202 (36.63%), Postives = 103/202 (50.99%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C + PC N C++ EF C C G++G+ CE ++++C NPC N G C D N FTC C F G +CQ + + C + C+NG C NG ++C+C GF G C I K + C +HG C + + C C+PGYTG RC+ + C S+ C NGG C L N IC+C+ +G NC I
Sbjct: 411 CLSMPCQNDATCLDRIG-EFTCICMPGYQGKYCEVDIDECESNPCVNDGICRDMVNG-FTCTCQPGFTGTMCQIDIDECASTPCQNGAKCIDRPNG-YECRCAEGFEGRLCESN------IDNCKPDPC-HHGTC-VDGIASYTCNCEPGYTGYRCENQLNE-----CHSNPCQNGGKCVDLVNKY-ICQCQHGTSGTNCEI 595 HSP 4 Score: 99.3673 bits (246), Expect = 2.205e-20 Identity = 78/279 (27.96%), Postives = 114/279 (40.86%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL------CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVN----------------------------------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+N F CL ++ C + PC NG + + C+C G+ G CE NV DC ++ C NGGTC D N F C C + F G+ CQ+E PCLN C+NGG C ++ F C C G+ G +C + ++C V +++ ELC + G C + T +CKC YTG C+ + + C+ C NG C+ G C+C + G NC + E + N
Sbjct: 830 VNSFRCSCLPGFTGARCATELNECQSVPCKNGGTCTDYVNSYTCTCKPGFTGLLCETNVPDCTESSCFNGGTCTDGING-FKCTCRTGFTGDYCQYEVNECDSQPCLNGGICQDAMESYRCSCPKGYTGPRCQYPVDWCRPSNPCKNGGRCRQ-KDASFTCDCLGGWSGRYCDIPGVSCEVAARQRGRQTDELCLHGGHC-VNTGNTHYCKCPADYTGSYCESQFDH-----CEEKPCLNGATCRSYMGGF-TCDCMPGYEGNNCEREVNECQSHPCQN 1099 HSP 5 Score: 96.2857 bits (238), Expect = 2.015e-19 Identity = 82/244 (33.61%), Postives = 105/244 (43.03%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ------FENPCLN--------------VNCE--------NGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKI 985
C PC N G C + + F C C G++G C+ N+N+C +PC N GTC+D S FTC C + G C NPC N NC+ NGG+C N F+C C GF G CA + C +P C N G C Y N + C C PG+TG C+ +P C CFNGG C NG C C+ FTG C + E + +N I
Sbjct: 712 CLPSPCQNAGTCFDQLN-GFTCKCRQGFRGNLCQVNINECASSPCLNQGTCVDGVAS-FTCLCEPPYSGPTCAELLTPCSPNPCANHASCVHTPDYLGYQCNCQPGWQDPCLNGGSCTDGVNS-FRCSCLPGFTGARCATELNECQSVP------CKNGGTCTDYVN-SYTCTCKPGFTGLLCETN--VP---DCTESSCFNGGTCTDGINGF-KCTCRTGFTGDYCQYEVNECDSQPCLNGGI 939 HSP 6 Score: 88.1965 bits (217), Expect = 5.811e-17 Identity = 69/235 (29.36%), Postives = 118/235 (50.21%), Query Frame = 2
Query: 2243 DEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIK--MDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D YQ +SL + GE+ +H+AAR + ++A + ++ D GR+PL +++AADA + Q+LI + +++ +TALI A +L + M+ L+ + VN +D G+S +HW+A NN +E + D++D ++++PLFLAA EG+ ++VK LLA+F I MD P+ IA+E+ ++I L+ E
Sbjct: 1775 DLIYQGASLAA---QTDRTGETALHLAARYARADAAKRLLDAG--ADANAQDNTGRSPLHAAVAADA-QGVFQILIRNRATDLDAR-------------------MYDGSTALILAARLAVEGMVEELITCHADVNAVDEIGKSALHWAAAVNN---VEATIALLKNGANKDMQDLKEETPLFLAAREGSCEAVKVLLAHFANREITDHMDRL---PRDIAQERMHHDIVQLLDE 1978 HSP 7 Score: 83.1889 bits (204), Expect = 2.098e-15 Identity = 64/214 (29.91%), Postives = 95/214 (44.39%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQ-NPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C+ PC NG ++ + CSC G++G+ C ++++C + C NGG C++ S F C C + + G C+ PC C NGGTC + ++C C GF G C CP C N+G C N T C+C P +TG C + E + + C NGG C G C C +TG +C+ + + N
Sbjct: 100 CATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNTHGS-FRCECLTGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFRGHNCEDNVDDCP------GHKCMNNGICVDGVN-TYNCQCPPEWTGQYCAEDVN---ECLMQPNACHNGGTCFNTIGGH-TCVCVNGWTGDDCSENIDDCATAVCFN 301 HSP 8 Score: 77.0258 bits (188), Expect = 1.687e-13 Identity = 56/176 (31.82%), Postives = 81/176 (46.02%), Query Frame = 2
Query: 458 IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCES-LENGM--FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
PC+NGG CID + C C +IG+LCQ +PC C N C+S + N + + C C+ GF G+ C++ + AC P C N N C C PGY G C ++ K C NGG+C + +GS CEC ++G+ C +P + +N
Sbjct: 27 THRPCENGGMCIDSR-----CLCRPGYIGSLCQHLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQDCSLVD-ACATSPCANGARCTNW-------NNHYNCSCPPGYQGKNCRND----IDECRKPGKCLNGGIC-MNTHGSFRCECLTGYSGRTCEVPTQPCAPSQCLN 184 HSP 9 Score: 73.9442 bits (180), Expect = 1.299e-12 Identity = 63/210 (30.00%), Postives = 95/210 (45.24%), Query Frame = 2
Query: 341 CSNRPCVNGKC----VEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVN-CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C PC+N V P++ C C G++G+ C V+ C +PC NG C + N+ + C+C + G C+ + + C C NGG C + +G F+C+C G+ G C V P P + C N G C + T C C PG+ G C+ + C C N G+C V + C+C E+TG+ C + E
Sbjct: 59 CHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQDCSL-VDACATSPCANGARCTN-WNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNT-HGSFRCECLTGYSGRTCEVPTQ--PCAPSQ----CLNGGTCHQTGDHTYECACLPGFRGHNCEDNVD-----DCPGHKCMNNGIC-VDGVNTYNCQCPPEWTGQYCAEDVNE 253 HSP 10 Score: 70.0922 bits (170), Expect = 1.774e-11 Identity = 76/268 (28.36%), Postives = 106/268 (39.55%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLI-IKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKC 1150
C+NG FRC C G+ G TCE C + C NGGTC + + C C F G+ C+ + C C N G C N + C+C + G++CA C + P C+N G C + T C C G+TGD C + + C + CFNG C S CEC TG C L + + NE + ++C C A F G C+Q + C+ C+ + KC
Sbjct: 144 CLNGGICMNTHGSFRCECLTGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFRGHNCEDNVDDCPGHKCMNNGICVDGVN-TYNCQCPPEWTGQYCAEDVNECLMQPNA----CHNGGTCFNTIGGHT--CVCVNGWTGDDCSENID-----DCATAVCFNGATCHDR-VASFFCECPVGKTGLLC----------HLDDACVSNPCNEGAVCDTNPLNGRAIC--TCPAGFVGGACNQ--DMDECSIGANPCEHFGKC 384
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Match: notch3 (notch receptor 3 [Source:ZFIN;Acc:ZDB-GENE-000329-5]) HSP 1 Score: 154.836 bits (390), Expect = 2.878e-37 Identity = 143/552 (25.91%), Postives = 224/552 (40.58%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVN-------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP--ICECKGEFTGKN-----------------CTIPLKETRKEALINIKIP------------KTFNEKQLIIKKTKSPSL---CDNL------------------------CKASFENGICDQQCNTFACNYDGGDC----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDC---HKSSCKFHK--CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTVFNV-------------------TEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARV 1714
C +PC+NG ++ F C C G++G CE VN+C +PC+NGGTCID + C+C +G LC+ E+ C + C+N GTC G ++C C GF GE C C P +N +C PN C C PG+TG C + + C+S C NGGVC + + P C C+ + G N CT+ + R + P K + L ++T P C N C + +G+CD++CN+ C +DGGDC +PW +C C +FN+ C+ CNN +CLFD DC K ++ C++ Y + +CD+ CN+ +CG+DG DC + L +V++ + + ++ FLQKLS+ LR + F + E+N ++ L ++ C CF + + + +L A + +L P+ + V
Sbjct: 1105 CEEKPCLNGATCRSYMGGFTCDCMPGYEGNNCEREVNECQSHPCQNGGTCIDLV-GHYICSCPPGTLGVLCEINEDDCATPSWPRGMPKCQNNGTCVDRVGG-YRCNCPPGFTGERCEGDINECLSNPCNP----SNSLDCIQLPN-DYQCVCKPGFTGRGCQSRFSV-----CESQPCKNGGVCSLSGSSPPGYSCTCQLGYAGSNCERSMNCKELPCYNGGSCTLTTRGARCTCIQGFGGPLCQHRSNDGCSSKPCHNGGLCTEETSYPFFHCQCTNGWKGKRCEQKTGSSAPLPSPCPIADCFSKANDGVCDKECNSLDCRWDGGDCSLAVNPWARCAD---PRCWRLFNNSQCDEFCNNAECLFDNFDCINKEKVCNPIYEAYCTDHYADGLCDQGCNTEECGWDGLDCARKIPEDLAED-------------MLVIVVLLPPEELLRTQTAFLQKLSAILRTTLR-FRLDRNGDYMIRPYTGRETRIKRELNPQEVIGSIVYLEIDNRLCSQGSDDCFRNADSAAEYLGA-LSAREMLRFPYPIKEV 1626 HSP 2 Score: 121.324 bits (303), Expect = 4.594e-27 Identity = 82/203 (40.39%), Postives = 106/203 (52.22%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENP-CLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
CS PC+NG C + + FRCSC G+ G C +N+C PCKNGGTC D NS +TC C F G LC+ P C +C NGGTC NG F+C CR GF G++C + C P +C + E + C C GYTG RC + PV+ S+ C NGG C+ D S C+C G ++G+ C IP
Sbjct: 866 CSPNPCLNGGSCTDGVN-SFRCSCLPGFTGARCATELNECQSVPCKNGGTCTDYVNS-YTCTCKPGFTGLLCETNVPDCTESSCFNGGTCTDGING-FKCTCRTGFTGDYCQYEVNECDSQPCLNGGICQDAME-------SYRCSCPKGYTGPRC----QYPVDWCRPSNPCKNGGRCRQKD-ASFTCDCLGGWSGRYCDIP 1053 HSP 3 Score: 106.686 bits (265), Expect = 1.314e-22 Identity = 78/218 (35.78%), Postives = 104/218 (47.71%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFD-PEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKI 985
CS PC N CV D ++C+C GW+G C ++N+C NPCKN GTC + + C+C + + G C+ + N C C NGG+C N F+C C GF G CA + C +P C N G C Y N + C C PG+TG C+ +P C CFNGG C NG C C+ FTG C + E + +N I
Sbjct: 788 CSPNPCANHASCVHTPDYLGYQCNCQPGWQGHLCNNDINECTSNPCKNRGTCTNTLGG-YVCSCRAGYTGPNCETDINDCSPNPCLNGGSCTDGVNS-FRCSCLPGFTGARCATELNECQSVP------CKNGGTCTDYVN-SYTCTCKPGFTGLLCETN--VP---DCTESSCFNGGTCTDGINGF-KCTCRTGFTGDYCQYEVNECDSQPCLNGGI 990 HSP 4 Score: 106.301 bits (264), Expect = 1.971e-22 Identity = 77/208 (37.02%), Postives = 96/208 (46.15%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETR 958
C++ PC N G C + CSC G+ G CE ++NDC NPC NGG+C D NS F C+C F G C E N C +V C+NGGTC N + C C+ GF G C +P C N G C N C C G+TGD C + C S C NGG+C+ S C C +TG C P+ R
Sbjct: 828 CTSNPCKNRGTCTNTLG-GYVCSCRAGYTGPNCETDINDCSPNPCLNGGSCTDGVNS-FRCSCLPGFTGARCATELNECQSVPCKNGGTCTDYVNS-YTCTCKPGFTGLLCETN------VPDCTESSCFNGGTCTDGIN-GFKCTCRTGFTGDYCQYEVNE-----CDSQPCLNGGICQDAME-SYRCSCPKGYTGPRCQYPVDWCR 1019 HSP 5 Score: 101.293 bits (251), Expect = 5.686e-21 Identity = 74/202 (36.63%), Postives = 103/202 (50.99%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C + PC N C++ EF C C G++G+ CE ++++C NPC N G C D N FTC C F G +CQ + + C + C+NG C NG ++C+C GF G C I K + C +HG C + + C C+PGYTG RC+ + C S+ C NGG C L N IC+C+ +G NC I
Sbjct: 411 CLSMPCQNDATCLDRIG-EFTCICMPGYQGKYCEVDIDECESNPCVNDGICRDMVNG-FTCTCQPGFTGTMCQIDIDECASTPCQNGAKCIDRPNG-YECRCAEGFEGRLCESN------IDNCKPDPC-HHGTC-VDGIASYTCNCEPGYTGYRCENQLNE-----CHSNPCQNGGKCVDLVNKY-ICQCQHGTSGTNCEI 595 HSP 6 Score: 88.5817 bits (218), Expect = 4.845e-17 Identity = 69/235 (29.36%), Postives = 118/235 (50.21%), Query Frame = 2
Query: 2243 DEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIK--MDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D YQ +SL + GE+ +H+AAR + ++A + ++ D GR+PL +++AADA + Q+LI + +++ +TALI A +L + M+ L+ + VN +D G+S +HW+A NN +E + D++D ++++PLFLAA EG+ ++VK LLA+F I MD P+ IA+E+ ++I L+ E
Sbjct: 1826 DLIYQGASLAA---QTDRTGETALHLAARYARADAAKRLLDAG--ADANAQDNTGRSPLHAAVAADA-QGVFQILIRNRATDLDAR-------------------MYDGSTALILAARLAVEGMVEELITCHADVNAVDEIGKSALHWAAAVNN---VEATIALLKNGANKDMQDLKEETPLFLAAREGSCEAVKVLLAHFANREITDHMDRL---PRDIAQERMHHDIVQLLDE 2029 HSP 7 Score: 84.7297 bits (208), Expect = 6.741e-16 Identity = 71/213 (33.33%), Postives = 91/213 (42.72%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLC-QFENPCLNVNCENGGTCESLENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTL---FCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRK 961
C PC N G C + + F C C G++G C+ N+N+C +PC N GTC+D S FTC C + G C + PC C N +C + + +QC C+ G+ G C C P K R C N TL C C GYTG C+ C + C NGG C N S C C FTG C L E +
Sbjct: 712 CLPSPCQNAGTCFDQLN-GFTCKCRQGFRGNLCQVNINECASSPCLNQGTCVDGVAS-FTCLCEPPYSGPTCAELLTPCSPNPCANHASCVHTPDYLGYQCNCQPGWQGHLCNNDINECTSNPCKNRGTCTN----------TLGGYVCSCRAGYTGPNCETDIN-----DCSPNPCLNGGSCTDGVN-SFRCSCLPGFTGARCATELNECQS 906 HSP 8 Score: 82.8037 bits (203), Expect = 2.622e-15 Identity = 64/214 (29.91%), Postives = 95/214 (44.39%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQ-NPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C+ PC NG ++ + CSC G++G+ C ++++C + C NGG C++ S F C C + + G C+ PC C NGGTC + ++C C GF G C CP C N+G C N T C+C P +TG C + E + + C NGG C G C C +TG +C+ + + N
Sbjct: 100 CATSPCANGARCTNWNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNTHGS-FRCECLTGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFRGHNCEDNVDDCP------GHKCMNNGICVDGVN-TYNCQCPPEWTGQYCAEDVN---ECLMQPNACHNGGTCFNTIGGH-TCVCVNGWTGDDCSENIDDCATAVCFN 301 HSP 9 Score: 79.337 bits (194), Expect = 2.783e-14 Identity = 71/213 (33.33%), Postives = 94/213 (44.13%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDC-IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVN-----------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C ++PC+NG + +RCSC G+ G C+ V+ C NPCKNGG C +K++ FTC+C + G C V C +GG C + N + CKC + G +C Q C P C N C Y M F C C PGY G+ C+++ C+S C NGG C L G IC C G C I
Sbjct: 980 CDSQPCLNGGICQDAMESYRCSCPKGYTGPRCQYPVDWCRPSNPCKNGGRC-RQKDASFTCDCLGGWSGRYCDIPGVSCEVAARQRGRQTDELCLHGGHCVNTGNTHY-CKCPADYTGSYCESQFDHCEEKP------CLNGATCRSY--MGGFTCDCMPGYEGNNCEREVNE-----CQSHPCQNGGTCIDL-VGHYICSCPPGTLGVLCEI 1176 HSP 10 Score: 76.6406 bits (187), Expect = 2.004e-13 Identity = 56/176 (31.82%), Postives = 81/176 (46.02%), Query Frame = 2
Query: 458 IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCES-LENGM--FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
PC+NGG CID + C C +IG+LCQ +PC C N C+S + N + + C C+ GF G+ C++ + AC P C N N C C PGY G C ++ K C NGG+C + +GS CEC ++G+ C +P + +N
Sbjct: 27 THRPCENGGMCIDSR-----CLCRPGYIGSLCQHLDPCHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQDCSLVD-ACATSPCANGARCTNW-------NNHYNCSCPPGYQGKNCRND----IDECRKPGKCLNGGIC-MNTHGSFRCECLTGYSGRTCEVPTQPCAPSQCLN 184 HSP 11 Score: 73.559 bits (179), Expect = 1.664e-12 Identity = 63/210 (30.00%), Postives = 95/210 (45.24%), Query Frame = 2
Query: 341 CSNRPCVNGKC----VEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVN-CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C PC+N V P++ C C G++G+ C V+ C +PC NG C + N+ + C+C + G C+ + + C C NGG C + +G F+C+C G+ G C V P P + C N G C + T C C PG+ G C+ + C C N G+C V + C+C E+TG+ C + E
Sbjct: 59 CHRSPCLNAAACKSQVANSIPQYTCVCQRGFRGQDCSL-VDACATSPCANGARCTN-WNNHYNCSCPPGYQGKNCRNDIDECRKPGKCLNGGICMNT-HGSFRCECLTGYSGRTCEVPTQ--PCAPSQ----CLNGGTCHQTGDHTYECACLPGFRGHNCEDNVD-----DCPGHKCMNNGIC-VDGVNTYNCQCPPEWTGQYCAEDVNE 253 HSP 12 Score: 70.0922 bits (170), Expect = 2.197e-11 Identity = 76/268 (28.36%), Postives = 106/268 (39.55%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLI-IKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKC 1150
C+NG FRC C G+ G TCE C + C NGGTC + + C C F G+ C+ + C C N G C N + C+C + G++CA C + P C+N G C + T C C G+TGD C + + C + CFNG C S CEC TG C L + + NE + ++C C A F G C+Q + C+ C+ + KC
Sbjct: 144 CLNGGICMNTHGSFRCECLTGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFRGHNCEDNVDDCPGHKCMNNGICVDGVN-TYNCQCPPEWTGQYCAEDVNECLMQPNA----CHNGGTCFNTIGGHT--CVCVNGWTGDDCSENID-----DCATAVCFNGATCHDR-VASFFCECPVGKTGLLC----------HLDDACVSNPCNEGAVCDTNPLNGRAIC--TCPAGFVGGACNQ--DMDECSIGANPCEHFGKC 384
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 166.777 bits (421), Expect = 7.553e-41 Identity = 156/546 (28.57%), Postives = 231/546 (42.31%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDC--------IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC-KVLDNGSPICECKGEFTGKNCTIPL---------------KETRKEALINIKIPKTFN-------EKQLI------IKKTKSPSLCDN-LCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTM--QNFTKYKSEFLQKLSSSLRMVVTVFNVTEINFNF------ATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQEL--------PIYTM 1768
C + PC NG C++ + ++CSC G +G CE NV+DC ++ C N G CID+ + C C F+G C+ + N CL+ C+ GT C L N ++C+CR GF G C C +P C N G C + N CKC PG+ G C+ C + C NGG C VL S C C +TG C P+ + + +E P FN + I I + +C+N C +N IC+ CN AC +DGGDC DPW+ C C FNDG C+ +CNN CL+DG DC K + + C + +Q+ CD+ CN+ +C +DG DC N L E L+++ M + FL++LS L V ++ + ++ L ++ QC QCF+S ++ FL A GN L++P+++ V ++ S E+ P+Y M
Sbjct: 876 CLSHPCHNGGTCIDLIN-TYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGG-YNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVND-YRCECRQGFTGRRCDSVVDGCKGLP------CRNGGTCAVASNTERGFICKCPPGFDGATCEYDART-----CGNLRCQNGGTCISVLK--SSKCVCSEGYTGATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCPTNFNGLFCHILDYGFIGGLGKNITPPDNEEICENEQCAELADNKICNANCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFNDGKCDSQCNNSGCLYDGFDCQKVEVQCNPLYDQYCRDHFQDGHCDQGCNNAECEWDGLDCDNMPEN----------------LAEGTLLIVVLMPPEKLKNNSVNFLRELSRVLHTNVVFKKDSKGEYKIYPYYGNEEESIVYLEIDNRQCYKSSSQCFTSATDVAAFLGALATHGN-LNIPYKIEAVKSKSHSVPSAGEIVETAKPPPPLYAM 1386 HSP 2 Score: 101.679 bits (252), Expect = 7.575e-21 Identity = 72/199 (36.18%), Postives = 95/199 (47.74%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C NRPC NG + + ++C+C G+ G CE +++DC NPC NGG+C D N F CNC + F G C+ + N C + C+NG C N + C C+ GF G C P C N G C I T C+C PG+TG+ C C S C NGG C+ G+ C C +TG NC
Sbjct: 562 CVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGIN-MFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNS-YTCTCQPGFSGIHCENN------TPDCTESSCFNGGTC-IDGINTFSCQCPPGFTGNYCQHDINE-----CDSKPCLNGGTCQD-SYGAYKCTCPQGYTGLNC 745 HSP 3 Score: 95.9005 bits (237), Expect = 3.601e-19 Identity = 81/270 (30.00%), Postives = 115/270 (42.59%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN-IKIPKTFNEKQLIIKKTKSPSLCDN---LCKAS--FENGICDQQCNTFAC 1111
V++ C + PC+NG + + C+C G++ C+ N+N+C NPC N GTCID + + CNC + G +C+ PC C+NGG C ES + F C+C G+ G+ C + C P + +C N N + C C PGY G C+ + C+ + C NGG C N C C F G C + E N N + S C+N C S F G C NTF+C
Sbjct: 442 VNNNECESNPCMNGGTCKDMTGAYICTCRAGFR-PNCQTNINECASNPCLNRGTCIDDV-AGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNT-------NGSYKCNCKPGYAGRHCETDID-----DCQPNPCHNGGSCSDGINMF-FCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSC 696 HSP 4 Score: 90.5077 bits (223), Expect = 1.724e-17 Identity = 66/213 (30.99%), Postives = 96/213 (45.07%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C++ PC++G C + + ++C C GW G C+ N N+C NPC NGGTC D + + C C + F N N C + C N GTC G ++C C + G C C P C N G C + F C+C PG+ G C+ C + C NG +C+ NGS C CK + G++C + + + N
Sbjct: 410 CNSNPCIHGTCHDGIN-GYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGA-YICTCRAGFRPNCQTNINECASNPCLNRGTCIDDVAG-YKCNCMLPYTGAICEAVLAPCSGSP------CKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNE-----CVNRPCRNGAMCQNT-NGSYKCNCKPGYAGRHCETDIDDCQPNPCHN 607 HSP 5 Score: 77.0258 bits (188), Expect = 2.458e-13 Identity = 55/184 (29.89%), Postives = 93/184 (50.54%), Query Frame = 2
Query: 2396 DEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D GRTPL +++AADA + Q+LI + +++ TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL ++ I MD P+ IA+E+ ++I L+ E
Sbjct: 1576 DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDAR-------------------MCDGTTPLILAARLAVEGMVEELINAHADVNAVDEFGKSALHWAAAVNNVDAAAVLLKSSANK---DMQNNKEETPLFLAAREGSYETAKVLLDHYANRDITDHMD---RLPRDIAQERMHHDIVHLLDE 1733 HSP 6 Score: 76.6406 bits (187), Expect = 2.564e-13 Identity = 56/208 (26.92%), Postives = 87/208 (41.83%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C ++PC+NG + ++C+C G+ G C+ V C +PCKNGG C N ++C+C+ G+ G +C V +++C V K++ LC N G C + T FC+C GYTG C+++ + C + C NG C G CEC + G NC+ + E
Sbjct: 714 CDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNN---------------------------------------FYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMC-VDTGNTHFCRCQAGYTGSYCEEQVDE-----CSPNPCQNGATCTDYLGGY-SCECVAGYHGVNCSEEINE 875 HSP 7 Score: 73.9442 bits (180), Expect = 1.712e-12 Identity = 84/296 (28.38%), Postives = 113/296 (38.18%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCT---------------------------SQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCD---NLCKAS--FENGICDQQCNTFACNYDGG 1126
C + PC N C++ EF+C C G++G CE N+++C NPC + G C+DK N +F C C S F GNLCQ + + C + C+NG C N + C+C GF G C C IP +G C T C C PGYTG CD + + C NGG CK NG C C + C + E I+ N + S S CD N C+++ G C + C G
Sbjct: 193 CLSNPCQNDATCLDQIG-EFQCICMPGYEGLYCETNIDECASNPCLHNGKCVDKIN-EFHCECPTGKGAARHPRPGAVFGYAQFQARCRHRSCFNGNLCQHDVDECASTPCKNGAKCLDGPNS-YTCQCTEGFTGRHCEQDINEC--IPDPCH-----YGTCKDGI-ATFTCLCRPGYTGRLCDND----INECLSHNPCRNGGTCKDKINGF-TCVCPDGYHDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAG 472 HSP 8 Score: 71.633 bits (174), Expect = 9.415e-12 Identity = 78/267 (29.21%), Postives = 102/267 (38.20%), Query Frame = 2
Query: 215 HNFIKIIFNHQFQSELIMIFAKGFPMNVFILGCLLVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDN-GSPICECKGEFTGKNCTIPLKE-TRKEALINIKIPKTFNE 1003
H I II NH S L C + +L N C NG + C C +GW GE C EN++DC C +G TC D+ S F C C G LC +N C++ C G C++ NG C C G+ G C C + C + G C + C C GY G RC+ +++ C S+ C N C LD G C C + G C + E L N K NE
Sbjct: 10 HYIIYIILNHPQPSPLGQY-------------CTEDVDECQLMPNA-CQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVAS-FFCECPHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSL----GANPCEHGGRCTNTLG-SFQCNCPQGYAGPRCE------IDVNECLSNPCQNDATC--LDQIGEFQCICMPGYEGLYCETNIDECASNPCLHNGKCVDKINE 248
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 166.007 bits (419), Expect = 1.560e-40 Identity = 159/551 (28.86%), Postives = 233/551 (42.29%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDC--------IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC-KVLDNGSPICECKGEFTGKNCTIPL---------------KETRKEALINIKIPKTFN-------EKQLI------IKKTKSPSLCDN-LCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTM--QNFTKYKSEFLQKLSSSLRMVVTVF-------------------NVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTM 1768
C + PC NG C++ + ++CSC G +G CE NV+DC ++ C N G CID+ + C C F+G C+ + N CL+ C+ GT C L N ++C+CR GF G C C +P C N G C + N CKC PG+ G C+ C + C NGG C VL S C C +TG C P+ + + +E P FN + I I + +C+N C +N IC+ CN AC +DGGDC DPW+ C C FNDG C+ +CNN CL+DG DC K + + C + +Q+ CD+ CN+ +C +DG DC N L E L+++ M + FL++LS L V VF E++ ++ L ++ QC QCF+S ++ FL A GN L++P+++ V + I+ +K P+Y M
Sbjct: 1113 CLSHPCHNGGTCIDLIN-TYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGG-YNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVND-YRCECRQGFTGRRCDSVVDGCKGLP------CRNGGTCAVASNTERGFICKCPPGFDGATCEYDART-----CGNLRCQNGGTCISVLK--SSKCVCSEGYTGATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCPTNFNGLFCHILDYGFIGGLGKNITPPDNEEICENEQCAELADNKICNANCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFNDGKCDSQCNNSGCLYDGFDCQKVEVQCNPLYDQYCRDHFQDGHCDQGCNNAECEWDGLDCDNMPEN----------------LAEGTLLIVVLMPPEKLKNNSVNFLRELSRVLHTNV-VFKKDSKGEYKIYPYYGNEEERRRELDQMEVRGSIVYLEIDNRQCYKSSSQCFTSATDVAAFLGALATHGN-LNIPYKIEAVKSEIVETAKPPP-PLYAM 1626 HSP 2 Score: 100.138 bits (248), Expect = 1.842e-20 Identity = 72/199 (36.18%), Postives = 95/199 (47.74%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C NRPC NG + + ++C+C G+ G CE +++DC NPC NGG+C D N F CNC + F G C+ + N C + C+NG C N + C C+ GF G C P C N G C I T C+C PG+TG+ C C S C NGG C+ G+ C C +TG NC
Sbjct: 797 CVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGIN-MFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNS-YTCTCQPGFSGIHCENN------TPDCTESSCFNGGTC-IDGINTFSCQCPPGFTGNYCQHDINE-----CDSKPCLNGGTCQD-SYGAYKCTCPQGYTGLNC 980 HSP 3 Score: 94.7449 bits (234), Expect = 8.808e-19 Identity = 81/270 (30.00%), Postives = 115/270 (42.59%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN-IKIPKTFNEKQLIIKKTKSPSLCDN---LCKAS--FENGICDQQCNTFAC 1111
V++ C + PC+NG + + C+C G++ C+ N+N+C NPC N GTCID + + CNC + G +C+ PC C+NGG C ES + F C+C G+ G+ C + C P + +C N N + C C PGY G C+ + C+ + C NGG C N C C F G C + E N N + S C+N C S F G C NTF+C
Sbjct: 677 VNNNECESNPCMNGGTCKDMTGAYICTCRAGFR-PNCQTNINECASNPCLNRGTCIDDV-AGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNT-------NGSYKCNCKPGYAGRHCETDID-----DCQPNPCHNGGSCSDGINMF-FCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSC 931 HSP 4 Score: 82.8037 bits (203), Expect = 4.045e-15 Identity = 71/211 (33.65%), Postives = 97/211 (45.97%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL 946
C++ PC GKC++ D + C+C G+ G+ C N+++C NPC+NGGTC DK N FTC C + ++C E NPC++ GTC NG ++C C G+ G C V N C P C N G C +MT C C G+ + I C S+ C N G C + D C C +TG C L
Sbjct: 570 CASNPCDYGKCIDKID-GYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKING-FTCVCPDGYHDHMCLSEVNECNSNPCIH------GTCHDGING-YKCDCDAGWSGSNCDVNNNECESNP------CMNGGTCK---DMTGAYICTCRAGF-------RPNCQTNINECASNPCLNRGTC-IDDVAGYKCNCMLPYTGAICEAVL 754 HSP 5 Score: 82.4185 bits (202), Expect = 5.669e-15 Identity = 71/236 (30.08%), Postives = 106/236 (44.92%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCK----------CRYGFI--GEFCAVQNIACPV--------------IPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEA 967
C++ PC NG F+ ++ C C G+ G TC++++N+C QNPC+NGG C+++ S + CNC ++F G C+ PC C NGGTC ++ ++C C + FI G C C V I C N G C N T C+C P +TG C + + E + C NGG C G C C +TG++C+ + + A
Sbjct: 77 CASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGS-YRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTSYCVPRTFLLCIFVFIHMGGRCHSTLPTCLVLFPTGFSGQNCEENIDDCPSNNCRNGGTCVDGVN-TYNCQCPPDWTGQYCTEDVD---ECQLMPNACQNGGTCHNTYGGY-NCVCVNGWTGEDCSENIDDCANAA 306 HSP 6 Score: 79.337 bits (194), Expect = 4.442e-14 Identity = 104/369 (28.18%), Postives = 146/369 (39.57%), Query Frame = 2
Query: 365 GKCVEAFDPEFRCSCWHGWKGETCEENVNDC--IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYP-NMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN-IKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCK------FHKCSELYQNKICD---EECNSPQCGFDGGDCHTSRSNSFFSN--EGLTKCSTQTKL 1423
G CV+ + + C C W G+ C E+V++C + N C+NGGTC + + C C + + G C + C N C +G TC F C+C +G G C + N AC P CN CD P N C C PGYTG C+ + E ++ C +GG C GS C C + G C I + E N E Q I P NLC+ + C A DG + + G +HC+ N+ + +P CH +CK C Y ++CD EC S C +GG C T R N + +G T + +T L
Sbjct: 233 GTCVDGVN-TYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGG-YNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFF-CECPHGRTGLLCHLDN-ACISNP------CNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVD---ECSLGANPCEHGGRCTNTL-GSFQCNCPQGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICM----PGFNGNLCQHDVDE-CASTPCKNGAKCLDGPNSYTCQCTEGFTGRHCEQDINECIPDP-------------CHYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSQPCQ-NGGQC-TDRENGYICTCPKGTTGVNCETNL 567 HSP 7 Score: 79.337 bits (194), Expect = 4.634e-14 Identity = 85/306 (27.78%), Postives = 116/306 (37.91%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE--------------------------------------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCD---NLCKAS--FENGICDQQCNTFACNYDGG 1126
C + PC N C++ EF+C C G+ G C+ +V++C PCKNG C+D NS +TC CT F G C+ + N CL+ C+NGG C ENG + C C G G C C P ++G+C I C C+PGYTG C+ + C S+ C NGG CK NG C C + C + E I+ N + S S CD N C+++ G C + C G
Sbjct: 419 CLSNPCQNDATCLDQIG-EFQCICMPGFNGNLCQHDVDECASTPCKNGAKCLDGPNS-YTCQCTEGFTGRHCEQDINECIPDPCHYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENG-YICTCPKGTTGVNCETNLDDCASNPC-------DYGKC-IDKIDGYECTCEPGYTGKMCNINIDE-----CASNPCRNGGTCKDKINGF-TCVCPDGYHDHMCLSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAG 707 HSP 8 Score: 77.0258 bits (188), Expect = 2.225e-13 Identity = 55/184 (29.89%), Postives = 93/184 (50.54%), Query Frame = 2
Query: 2396 DEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D GRTPL +++AADA + Q+LI + +++ TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL ++ I MD P+ IA+E+ ++I L+ E
Sbjct: 1829 DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDAR-------------------MCDGTTPLILAARLAVEGMVEELINAHADVNAVDEFGKSALHWAAAVNNVDAAAVLLKSSANK---DMQNNKEETPLFLAAREGSYETAKVLLDHYANRDITDHMD---RLPRDIAQERMHHDIVHLLDE 1986 HSP 9 Score: 75.0998 bits (183), Expect = 7.690e-13 Identity = 56/169 (33.14%), Postives = 77/169 (45.56%), Query Frame = 2
Query: 392 EFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTC-IDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGS 892
+F C C G+ + C V N C+ NPC+NGGTC + S + C C + G+ CQ +PC + C NGG C E + CKC GF G C C P C N G+C + + C C +TG C++ + C C NGG C+ D+ S
Sbjct: 16 DFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADPCASNPCANGGKCLPFET-QYICKCPSGFHGATCKQDINECSQNP------CRNGGQC-LNEFGSYRCNCQNRFTGRNCEEPY-----VPCNPSPCLNGGTCRQTDDTS 171 HSP 10 Score: 74.7146 bits (182), Expect = 1.007e-12 Identity = 56/210 (26.67%), Postives = 87/210 (41.43%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK------RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C ++PC+NG + ++C+C G+ G C+ V C +PCKNGG C N ++C+C+ G+ G +C V +++C V K++ LC N G C + T FC+C GYTG C+++ + C + C NG C G CEC + G NC+ + E
Sbjct: 949 CDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNN---------------------------------------FYRCECKSGWTGVYCDVPSVSCEVAAKQQGKGVDIAHLCRNSGMC-VDTGNTHFCRCQAGYTGSYCEEQVDE-----CSPNPCQNGATCTDYLGGY-SCECVAGYHGVNCSEEINE 1112 HSP 11 Score: 72.4034 bits (176), Expect = 6.175e-12 Identity = 103/380 (27.11%), Postives = 144/380 (37.89%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYC---------------FNGGVC----------------KVLDN-GSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICD---QQCNTFACNYDGGDCDPWRKCY------GNDLKHCKGVFNDGVCNPECNNVDCL--FDGEDCHKSSCKFHKCSELYQNKICD---EECNSPQCGFDGGDC 1354
C NG + C C +GW GE C EN++DC C +G TC D+ S F C C G LC +N C++ C G C++ NG C C G+ G C C + C + G C + C C GY G RC+ + C++D FNG +C K LD S C+C FTG++C E IN IP + K + C LC+ + +CD +C + C +GG C Y G +C+ +D NP C+ C+ DG +C C Y K+C+ +EC S C +GG C
Sbjct: 269 CQNGGTCHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVAS-FFCECPHGRTGLLCHLDNACISNPCNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSL----GANPCEHGGRCTNTLG-SFQCNCPQGYAGPRCEIDVNECLSNPCQNDATCLDQIGEFQCICMPGFNGNLCQHDVDECASTPCKNGAKCLDGPNSYTCQCTEGFTGRHC---------EQDINECIPDPCHYG--TCKDGIATFTC--LCRPGYTGRLCDNDINECLSQPCQ-NGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNP-CDYGKCIDKIDGYEC--------TCEPGYTGKMCNINIDECASNPC-RNGGTC 618 HSP 12 Score: 63.5438 bits (153), Expect = 2.744e-9 Identity = 52/158 (32.91%), Postives = 72/158 (45.57%), Query Frame = 2
Query: 512 FTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
FTC+C F +C +N C+N C NGGTCE L + ++C+C G+ G+ C Q C P C N G+C + CKC G+ G C + C + C NGG C + + GS C C+ FTG+NC P +N
Sbjct: 17 FTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQ-QADPCASNP------CANGGKCLPF-ETQYICKCPSGFHGATCKQDINE-----CSQNPCRNGGQC-LNEFGSYRCNCQNRFTGRNCEEPYVPCNPSPCLN 160
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 160.614 bits (405), Expect = 6.779e-39 Identity = 161/568 (28.35%), Postives = 239/568 (42.08%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDC--------IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC-KVLDNGSPICECKGEFTGKNCTIPL---------------KETRKEALINIKIPKTFN-------EKQLI------IKKTKSPSLCDN-LCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSN---------SFFSNEGLTKCSTQTKLYELDLVLMTTM----------------QNFTKYKSEFLQKLSSS--LRMVVTVFNVT-----------EINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTM 1768
C + PC NG C++ + ++CSC G +G CE NV+DC ++ C N G CID+ + C C F+G C+ + N CL+ C+ GT C L N ++C+CR GF G C C +P C N G C + N CKC PG+ G C+ C + C NGG C VL S C C +TG C P+ + + +E P FN + I I + +C+N C +N IC+ CN AC +DGGDC DPW+ C C FNDG C+ +CNN CL+DG DC K + + C + +Q+ CD+ CN+ +C +DG DC N E L K ++ L EL VL T + N + K ++K S++ +F+ E++ ++ L ++ QC QCF+S ++ FL A GN L++P+++ V + I+ +K P+Y M
Sbjct: 1110 CLSHPCHNGGTCIDLIN-TYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGG-YNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVND-YRCECRQGFTGRRCDSVVDGCKGLP------CRNGGTCAVASNTERGFICKCPPGFDGATCEYDART-----CGNLRCQNGGTCISVLK--SSKCVCSEGYTGATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCPTNFNGLFCHILDYGFIGGLGKNITPPDNEEICENEQCAELADNKICNANCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFNDGKCDSQCNNSGCLYDGFDCQKVEVQCNPLYDQYCRDHFQDGHCDQGCNNAECEWDGLDCDNMPENLAEGTLLIVVLMPPEKL-KNNSVNFLRELSRVLHTNVVFKKDSKGEYKIYPYYGNEEELKKHHIKKRSAASWSDAPTAIFSTMKESVLPGRRRRELDQMEVRGSIVYLEIDNRQCYKSSSQCFTSATDVAAFLGALATHGN-LNIPYKIEAVKSEIVETAKPPP-PLYAM 1656 HSP 2 Score: 102.834 bits (255), Expect = 3.248e-21 Identity = 82/271 (30.26%), Postives = 118/271 (43.54%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL------CSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVN---------------------------------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
+N+F C K C++ PC NG C + + + C+C G+ G CE N DC ++ C NGGTCID N+ F+C C F GN CQ + PCLN C+NGG C N ++C+C+ G+ G +C V +++C V K++ LC N G C + T FC+C GYTG C+++ + C + C NG C G CEC + G NC+ + E
Sbjct: 849 INMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVN-SYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGINT-FSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNN-FYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMC-VDTGNTHFCRCQAGYTGSYCEEQVDE-----CSPNPCQNGATCTDYLGGY-SCECVAGYHGVNCSEEINE 1109 HSP 3 Score: 100.523 bits (249), Expect = 1.485e-20 Identity = 69/200 (34.50%), Postives = 102/200 (51.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCT 937
C++ PC NG F+ ++ C C G+ G TC++++N+C QNPC+NGG C+++ S + CNC ++F G C+ PC C NGGTC ++ ++C C GF G+ C CP C N G C N T C+C P +TG C + + E + C NGG C G C C +TG++C+
Sbjct: 145 CASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGS-YRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCP------SNNCRNGGTCVDGVN-TYNCQCPPDWTGQYCTEDVD---ECQLMPNACQNGGTCHNTYGGY-NCVCVNGWTGEDCS 332 HSP 4 Score: 100.523 bits (249), Expect = 1.549e-20 Identity = 82/270 (30.37%), Postives = 115/270 (42.59%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN-IKIPKTFNEKQLIIKKTKSPSLCDN---LCKAS--FENGICDQQCNTFAC 1111
V++ C + PC+NG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G +C+ PC C+NGG C ES + F C+C G+ G+ C + C P + +C N N + C C PGY G C+ + C+ + C NGG C N C C F G C + E N N + S C+N C S F G C NTF+C
Sbjct: 675 VNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDV-AGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNT-------NGSYKCNCKPGYAGRHCETDID-----DCQPNPCHNGGSCSDGINMF-FCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSC 930 HSP 5 Score: 100.138 bits (248), Expect = 1.914e-20 Identity = 72/199 (36.18%), Postives = 95/199 (47.74%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C NRPC NG + + ++C+C G+ G CE +++DC NPC NGG+C D N F CNC + F G C+ + N C + C+NG C N + C C+ GF G C P C N G C I T C+C PG+TG+ C C S C NGG C+ G+ C C +TG NC
Sbjct: 796 CVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGIN-MFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNS-YTCTCQPGFSGIHCENN------TPDCTESSCFNGGTC-IDGINTFSCQCPPGFTGNYCQHDINE-----CDSKPCLNGGTCQD-SYGAYKCTCPQGYTGLNC 979 HSP 6 Score: 92.8189 bits (229), Expect = 3.386e-18 Identity = 72/216 (33.33%), Postives = 99/216 (45.83%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C ++PC NG + + C+C G G CE N++DC NPC + G CIDK + + C C + G +C + C + C NGGTC+ NG F C C G+ C + C P I HG C N C CD G++G CD C+S+ C NGG CK + G+ IC C+ F+G NC + E +N
Sbjct: 530 CLSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPC-DYGKCIDKIDG-YECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKING-FTCVCPDGYHDHMCLSEVNECNSNPCI----------HGTCHDGIN-GYKCDCDAGWSGSNCDVNNNE-----CESNPCMNGGTCKDM-TGAYICTCRAGFSGPNCQTNINECASNPCLN 725 HSP 7 Score: 88.9669 bits (219), Expect = 4.918e-17 Identity = 72/210 (34.29%), Postives = 98/210 (46.67%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL 946
C++ PC GKC++ D + C+C G+ G+ C N+++C NPC+NGGTC DK N FTC C + ++C E NPC++ GTC NG ++C C G+ G C V N C P C N G C +MT C C G++G C C S+ C N G C + D C C +TG C L
Sbjct: 568 CASNPCDYGKCIDKID-GYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKING-FTCVCPDGYHDHMCLSEVNECNSNPCIH------GTCHDGING-YKCDCDAGWSGSNCDVNNNECESNP------CMNGGTCK---DMTGAYICTCRAGFSGPNCQTNINE-----CASNPCLNRGTC-IDDVAGYKCNCMLPYTGAICEAVL 753 HSP 8 Score: 85.5001 bits (210), Expect = 6.451e-16 Identity = 62/183 (33.88%), Postives = 85/183 (46.45%), Query Frame = 2
Query: 392 EFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTC-IDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
+F C C G+ + C V N C+ NPC+NGGTC + S + C C + G+ CQ +PC + C NGG C E + CKC GF G C C P C N G+C + + C C +TG C++ + C C NGG C+ D+ S C C F+G+NC
Sbjct: 84 DFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADPCASNPCANGGKCLPFET-QYICKCPSGFHGATCKQDINECSQNP------CRNGGQC-LNEFGSYRCNCQNRFTGRNCEEPY-----VPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNC 253 HSP 9 Score: 77.0258 bits (188), Expect = 2.491e-13 Identity = 55/184 (29.89%), Postives = 93/184 (50.54%), Query Frame = 2
Query: 2396 DEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D GRTPL +++AADA + Q+LI + +++ TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL ++ I MD P+ IA+E+ ++I L+ E
Sbjct: 1880 DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDAR-------------------MCDGTTPLILAARLAVEGMVEELINAHADVNAVDEFGKSALHWAAAVNNVDAAAVLLKSSANK---DMQNNKEETPLFLAAREGSYETAKVLLDHYANRDITDHMD---RLPRDIAQERMHHDIVHLLDE 2037 HSP 10 Score: 75.8702 bits (185), Expect = 5.367e-13 Identity = 58/174 (33.33%), Postives = 77/174 (44.25%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPC-LNVNCENGGTCES--LENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C NGG C C C+S + G CQ+ NPC L C N GTCE L N + F C C GF + C PV C N G C++ +++ + C+C PG+TGD C + C S+ C NGG C + IC+C F G C + E + N
Sbjct: 29 CLNGGRCEMTPGGTGVCLCSSSYFGERCQYPNPCALKNQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLT-----PVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADP------CASNPCANGGKCLPFET-QYICKCPSGFHGATCKQDINECSQNPCRN 190
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 160.229 bits (404), Expect = 9.236e-39 Identity = 161/568 (28.35%), Postives = 239/568 (42.08%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDC--------IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC-KVLDNGSPICECKGEFTGKNCTIPL---------------KETRKEALINIKIPKTFN-------EKQLI------IKKTKSPSLCDN-LCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSN---------SFFSNEGLTKCSTQTKLYELDLVLMTTM----------------QNFTKYKSEFLQKLSSS--LRMVVTVFNVT-----------EINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTM 1768
C + PC NG C++ + ++CSC G +G CE NV+DC ++ C N G CID+ + C C F+G C+ + N CL+ C+ GT C L N ++C+CR GF G C C +P C N G C + N CKC PG+ G C+ C + C NGG C VL S C C +TG C P+ + + +E P FN + I I + +C+N C +N IC+ CN AC +DGGDC DPW+ C C FNDG C+ +CNN CL+DG DC K + + C + +Q+ CD+ CN+ +C +DG DC N E L K ++ L EL VL T + N + K ++K S++ +F+ E++ ++ L ++ QC QCF+S ++ FL A GN L++P+++ V + I+ +K P+Y M
Sbjct: 1186 CLSHPCHNGGTCIDLIN-TYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGG-YNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVND-YRCECRQGFTGRRCDSVVDGCKGLP------CRNGGTCAVASNTERGFICKCPPGFDGATCEYDART-----CGNLRCQNGGTCISVLK--SSKCVCSEGYTGATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCPTNFNGLFCHILDYGFIGGLGKNITPPDNEEICENEQCAELADNKICNANCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFNDGKCDSQCNNSGCLYDGFDCQKVEVQCNPLYDQYCRDHFQDGHCDQGCNNAECEWDGLDCDNMPENLAEGTLLIVVLMPPEKL-KNNSVNFLRELSRVLHTNVVFKKDSKGEYKIYPYYGNEEELKKHHIKKRSAASWSDAPTAIFSTMKESVLPGRRRRELDQMEVRGSIVYLEIDNRQCYKSSSQCFTSATDVAAFLGALATHGN-LNIPYKIEAVKSEIVETAKPPP-PLYAM 1732 HSP 2 Score: 102.449 bits (254), Expect = 3.806e-21 Identity = 82/271 (30.26%), Postives = 118/271 (43.54%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL------CSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVN---------------------------------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
+N+F C K C++ PC NG C + + + C+C G+ G CE N DC ++ C NGGTCID N+ F+C C F GN CQ + PCLN C+NGG C N ++C+C+ G+ G +C V +++C V K++ LC N G C + T FC+C GYTG C+++ + C + C NG C G CEC + G NC+ + E
Sbjct: 925 INMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVN-SYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGINT-FSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNN-FYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMC-VDTGNTHFCRCQAGYTGSYCEEQVDE-----CSPNPCQNGATCTDYLGGY-SCECVAGYHGVNCSEEINE 1185 HSP 3 Score: 100.138 bits (248), Expect = 1.862e-20 Identity = 69/200 (34.50%), Postives = 102/200 (51.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCT 937
C++ PC NG F+ ++ C C G+ G TC++++N+C QNPC+NGG C+++ S + CNC ++F G C+ PC C NGGTC ++ ++C C GF G+ C CP C N G C N T C+C P +TG C + + E + C NGG C G C C +TG++C+
Sbjct: 145 CASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGS-YRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCP------SNNCRNGGTCVDGVN-TYNCQCPPDWTGQYCTEDVD---ECQLMPNACQNGGTCHNTYGGY-NCVCVNGWTGEDCS 332 HSP 4 Score: 100.138 bits (248), Expect = 1.862e-20 Identity = 82/270 (30.37%), Postives = 115/270 (42.59%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN-IKIPKTFNEKQLIIKKTKSPSLCDN---LCKAS--FENGICDQQCNTFAC 1111
V++ C + PC+NG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G +C+ PC C+NGG C ES + F C+C G+ G+ C + C P + +C N N + C C PGY G C+ + C+ + C NGG C N C C F G C + E N N + S C+N C S F G C NTF+C
Sbjct: 751 VNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDV-AGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNT-------NGSYKCNCKPGYAGRHCETDID-----DCQPNPCHNGGSCSDGINMF-FCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSC 1006 HSP 5 Score: 100.138 bits (248), Expect = 2.339e-20 Identity = 72/199 (36.18%), Postives = 95/199 (47.74%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C NRPC NG + + ++C+C G+ G CE +++DC NPC NGG+C D N F CNC + F G C+ + N C + C+NG C N + C C+ GF G C P C N G C I T C+C PG+TG+ C C S C NGG C+ G+ C C +TG NC
Sbjct: 872 CVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGIN-MFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNS-YTCTCQPGFSGIHCENN------TPDCTESSCFNGGTC-IDGINTFSCQCPPGFTGNYCQHDINE-----CDSKPCLNGGTCQD-SYGAYKCTCPQGYTGLNC 1055 HSP 6 Score: 94.7449 bits (234), Expect = 1.010e-18 Identity = 76/206 (36.89%), Postives = 98/206 (47.57%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C + PC N C++ EF+C C G++G CE N+++C NPC + G C+DK N +F C C + F GNLCQ + + C + C+NG C N + C+C GF G C C IP +G C T C C PGYTG CD C S C NGG C +NG IC C TG NC L +
Sbjct: 455 CLSNPCQNDATCLDQIG-EFQCICMPGYEGLYCETNIDECASNPCLHNGKCVDKIN-EFHCECPTGFNGNLCQHDVDECASTPCKNGAKCLDGPNS-YTCQCTEGFTGRHCEQDINEC--IPDPCH-----YGTCKDGI-ATFTCLCRPGYTGRLCDNDINE-----CLSQPCQNGGQCTDRENGY-ICTCPKGTTGVNCETNLDD 643 HSP 7 Score: 88.9669 bits (219), Expect = 5.335e-17 Identity = 72/210 (34.29%), Postives = 98/210 (46.67%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL 946
C++ PC GKC++ D + C+C G+ G+ C N+++C NPC+NGGTC DK N FTC C + ++C E NPC++ GTC NG ++C C G+ G C V N C P C N G C +MT C C G++G C C S+ C N G C + D C C +TG C L
Sbjct: 644 CASNPCDYGKCIDKID-GYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKING-FTCVCPDGYHDHMCLSEVNECNSNPCIH------GTCHDGING-YKCDCDAGWSGSNCDVNNNECESNP------CMNGGTCK---DMTGAYICTCRAGFSGPNCQTNINE-----CASNPCLNRGTC-IDDVAGYKCNCMLPYTGAICEAVL 829 HSP 8 Score: 85.1149 bits (209), Expect = 8.008e-16 Identity = 62/183 (33.88%), Postives = 85/183 (46.45%), Query Frame = 2
Query: 392 EFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTC-IDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
+F C C G+ + C V N C+ NPC+NGGTC + S + C C + G+ CQ +PC + C NGG C E + CKC GF G C C P C N G+C + + C C +TG C++ + C C NGG C+ D+ S C C F+G+NC
Sbjct: 84 DFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADPCASNPCANGGKCLPFET-QYICKCPSGFHGATCKQDINECSQNP------CRNGGQC-LNEFGSYRCNCQNRFTGRNCEEPY-----VPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNC 253 HSP 9 Score: 77.0258 bits (188), Expect = 2.399e-13 Identity = 55/184 (29.89%), Postives = 93/184 (50.54%), Query Frame = 2
Query: 2396 DEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D GRTPL +++AADA + Q+LI + +++ TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL ++ I MD P+ IA+E+ ++I L+ E
Sbjct: 1956 DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDAR-------------------MCDGTTPLILAARLAVEGMVEELINAHADVNAVDEFGKSALHWAAAVNNVDAAAVLLKSSANK---DMQNNKEETPLFLAAREGSYETAKVLLDHYANRDITDHMD---RLPRDIAQERMHHDIVHLLDE 2113 HSP 10 Score: 75.485 bits (184), Expect = 6.275e-13 Identity = 58/174 (33.33%), Postives = 77/174 (44.25%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPC-LNVNCENGGTCES--LENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C NGG C C C+S + G CQ+ NPC L C N GTCE L N + F C C GF + C PV C N G C++ +++ + C+C PG+TGD C + C S+ C NGG C + IC+C F G C + E + N
Sbjct: 29 CLNGGRCEMTPGGTGVCLCSSSYFGERCQYPNPCALKNQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLT-----PVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADP------CASNPCANGGKCLPFET-QYICKCPSGFHGATCKQDINECSQNPCRN 190
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 159.844 bits (403), Expect = 1.125e-38 Identity = 161/568 (28.35%), Postives = 239/568 (42.08%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDC--------IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC-KVLDNGSPICECKGEFTGKNCTIPL---------------KETRKEALINIKIPKTFN-------EKQLI------IKKTKSPSLCDN-LCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSN---------SFFSNEGLTKCSTQTKLYELDLVLMTTM----------------QNFTKYKSEFLQKLSSS--LRMVVTVFNVT-----------EINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTM 1768
C + PC NG C++ + ++CSC G +G CE NV+DC ++ C N G CID+ + C C F+G C+ + N CL+ C+ GT C L N ++C+CR GF G C C +P C N G C + N CKC PG+ G C+ C + C NGG C VL S C C +TG C P+ + + +E P FN + I I + +C+N C +N IC+ CN AC +DGGDC DPW+ C C FNDG C+ +CNN CL+DG DC K + + C + +Q+ CD+ CN+ +C +DG DC N E L K ++ L EL VL T + N + K ++K S++ +F+ E++ ++ L ++ QC QCF+S ++ FL A GN L++P+++ V + I+ +K P+Y M
Sbjct: 1199 CLSHPCHNGGTCIDLIN-TYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGG-YNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVND-YRCECRQGFTGRRCDSVVDGCKGLP------CRNGGTCAVASNTERGFICKCPPGFDGATCEYDART-----CGNLRCQNGGTCISVLK--SSKCVCSEGYTGATCQYPVVSPCASRPCYNGGTCQFSPEEPFFQCFCPTNFNGLFCHILDYGFIGGLGKNITPPDNEEICENEQCAELADNKICNANCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFNDGKCDSQCNNSGCLYDGFDCQKVEVQCNPLYDQYCRDHFQDGHCDQGCNNAECEWDGLDCDNMPENLAEGTLLIVVLMPPEKL-KNNSVNFLRELSRVLHTNVVFKKDSKGEYKIYPYYGNEEELKKHHIKKRSAASWSDAPTAIFSTMKESVLPGRRRRELDQMEVRGSIVYLEIDNRQCYKSSSQCFTSATDVAAFLGALATHGN-LNIPYKIEAVKSEIVETAKPPP-PLYAM 1745 HSP 2 Score: 102.449 bits (254), Expect = 3.975e-21 Identity = 82/271 (30.26%), Postives = 118/271 (43.54%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL------CSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVN---------------------------------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
+N+F C K C++ PC NG C + + + C+C G+ G CE N DC ++ C NGGTCID N+ F+C C F GN CQ + PCLN C+NGG C N ++C+C+ G+ G +C V +++C V K++ LC N G C + T FC+C GYTG C+++ + C + C NG C G CEC + G NC+ + E
Sbjct: 938 INMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVN-SYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGINT-FSCQCPPGFTGNYCQHDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNN-FYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIAHLCRNSGMC-VDTGNTHFCRCQAGYTGSYCEEQVDE-----CSPNPCQNGATCTDYLGGY-SCECVAGYHGVNCSEEINE 1198 HSP 3 Score: 100.138 bits (248), Expect = 1.944e-20 Identity = 69/200 (34.50%), Postives = 102/200 (51.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCT 937
C++ PC NG F+ ++ C C G+ G TC++++N+C QNPC+NGG C+++ S + CNC ++F G C+ PC C NGGTC ++ ++C C GF G+ C CP C N G C N T C+C P +TG C + + E + C NGG C G C C +TG++C+
Sbjct: 158 CASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGS-YRCNCQNRFTGRNCEEPYVPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCP------SNNCRNGGTCVDGVN-TYNCQCPPDWTGQYCTEDVD---ECQLMPNACQNGGTCHNTYGGY-NCVCVNGWTGEDCS 345 HSP 4 Score: 100.138 bits (248), Expect = 2.098e-20 Identity = 82/270 (30.37%), Postives = 115/270 (42.59%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN-IKIPKTFNEKQLIIKKTKSPSLCDN---LCKAS--FENGICDQQCNTFAC 1111
V++ C + PC+NG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G +C+ PC C+NGG C ES + F C+C G+ G+ C + C P + +C N N + C C PGY G C+ + C+ + C NGG C N C C F G C + E N N + S C+N C S F G C NTF+C
Sbjct: 764 VNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDV-AGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNT-------NGSYKCNCKPGYAGRHCETDID-----DCQPNPCHNGGSCSDGINMF-FCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSC 1019 HSP 5 Score: 99.7525 bits (247), Expect = 2.548e-20 Identity = 72/199 (36.18%), Postives = 95/199 (47.74%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C NRPC NG + + ++C+C G+ G CE +++DC NPC NGG+C D N F CNC + F G C+ + N C + C+NG C N + C C+ GF G C P C N G C I T C+C PG+TG+ C C S C NGG C+ G+ C C +TG NC
Sbjct: 885 CVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGIN-MFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNS-YTCTCQPGFSGIHCENN------TPDCTESSCFNGGTC-IDGINTFSCQCPPGFTGNYCQHDINE-----CDSKPCLNGGTCQD-SYGAYKCTCPQGYTGLNC 1068 HSP 6 Score: 94.3597 bits (233), Expect = 1.073e-18 Identity = 76/206 (36.89%), Postives = 98/206 (47.57%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C + PC N C++ EF+C C G++G CE N+++C NPC + G C+DK N +F C C + F GNLCQ + + C + C+NG C N + C+C GF G C C IP +G C T C C PGYTG CD C S C NGG C +NG IC C TG NC L +
Sbjct: 468 CLSNPCQNDATCLDQIG-EFQCICMPGYEGLYCETNIDECASNPCLHNGKCVDKIN-EFHCECPTGFNGNLCQHDVDECASTPCKNGAKCLDGPNS-YTCQCTEGFTGRHCEQDINEC--IPDPCH-----YGTCKDGI-ATFTCLCRPGYTGRLCDNDINE-----CLSQPCQNGGQCTDRENGY-ICTCPKGTTGVNCETNLDD 656 HSP 7 Score: 88.5817 bits (218), Expect = 6.484e-17 Identity = 72/210 (34.29%), Postives = 98/210 (46.67%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL 946
C++ PC GKC++ D + C+C G+ G+ C N+++C NPC+NGGTC DK N FTC C + ++C E NPC++ GTC NG ++C C G+ G C V N C P C N G C +MT C C G++G C C S+ C N G C + D C C +TG C L
Sbjct: 657 CASNPCDYGKCIDKID-GYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKING-FTCVCPDGYHDHMCLSEVNECNSNPCIH------GTCHDGING-YKCDCDAGWSGSNCDVNNNECESNP------CMNGGTCK---DMTGAYICTCRAGFSGPNCQTNINE-----CASNPCLNRGTC-IDDVAGYKCNCMLPYTGAICEAVL 842 HSP 8 Score: 85.1149 bits (209), Expect = 8.360e-16 Identity = 62/183 (33.88%), Postives = 85/183 (46.45%), Query Frame = 2
Query: 392 EFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTC-IDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
+F C C G+ + C V N C+ NPC+NGGTC + S + C C + G+ CQ +PC + C NGG C E + CKC GF G C C P C N G+C + + C C +TG C++ + C C NGG C+ D+ S C C F+G+NC
Sbjct: 97 DFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADPCASNPCANGGKCLPFET-QYICKCPSGFHGATCKQDINECSQNP------CRNGGQC-LNEFGSYRCNCQNRFTGRNCEEPY-----VPCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNC 266 HSP 9 Score: 77.0258 bits (188), Expect = 2.463e-13 Identity = 55/184 (29.89%), Postives = 93/184 (50.54%), Query Frame = 2
Query: 2396 DEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D GRTPL +++AADA + Q+LI + +++ TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL ++ I MD P+ IA+E+ ++I L+ E
Sbjct: 1969 DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDAR-------------------MCDGTTPLILAARLAVEGMVEELINAHADVNAVDEFGKSALHWAAAVNNVDAAAVLLKSSANK---DMQNNKEETPLFLAAREGSYETAKVLLDHYANRDITDHMD---RLPRDIAQERMHHDIVHLLDE 2126 HSP 10 Score: 75.485 bits (184), Expect = 6.333e-13 Identity = 58/174 (33.33%), Postives = 77/174 (44.25%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPC-LNVNCENGGTCES--LENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C NGG C C C+S + G CQ+ NPC L C N GTCE L N + F C C GF + C PV C N G C++ +++ + C+C PG+TGD C + C S+ C NGG C + IC+C F G C + E + N
Sbjct: 42 CLNGGRCEMTPGGTGVCLCSSSYFGERCQYPNPCALKNQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLT-----PVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADP------CASNPCANGGKCLPFET-QYICKCPSGFHGATCKQDINECSQNPCRN 203
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Notch1 (notch 1 [Source:MGI Symbol;Acc:MGI:97363]) HSP 1 Score: 197.208 bits (500), Expect = 2.835e-50 Identity = 237/1013 (23.40%), Postives = 383/1013 (37.81%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS---------------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL----------------KETRKEALINIKIPKTFNEKQLII----------KKTKSPSLCDNL----CKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTS---------------------RSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQ----------KLSSSLRMVVTVFNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVN--ENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGR----------------------TPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
CS PC NG + F C C G+ G C E +N+C+ PC+NGGTCID NS +TC C F+G C+ + N CL+ C+ GT ++ F C+CR G G C VI + + C N G C + N C+C G+ G C+ C S C NGG C + SP C C G FTG C P + T + P FN I + P + + C+ N +C+ QCN AC +DGGDC DPW+ C C F+DG C+ +CN+ CLFDG DC + + + C + + + CD+ CNS +C +DG DC R+NSF L+ +++ D + + ++ E + SS L E++ ++ L ++ QCV QCF S ++ FL A G+ L++P+++ V + + +L + + A + GVLL K + ++ + S + G L D N+ +G+ +T + R PD ++R+ + ++ A L ++ T +DA DV +V+ + S G E N E ++ I+ + GA++ Q + + LH + R TPL ++++ADA + Q+L+ + +++ + TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL +F I MD P+ IA+E+ ++I L+ E
Sbjct: 1149 CSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGHTGRRCES------VINGCRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCENDART-----CGSLRCLNGGTC-ISGPRSPTCLCLGSFTGPECQFPASSPCVGSNPCYNQGTCEPTSENPFYRCLCPAKFNGLLCHILDYSFTGGAGRDIPPPQIEEACELPECQVDAGNKVCNLQCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQLTEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVPERLAAGTLVLVVLLPPDQLRNNSFHFLRELSHVLHTNVVFKRDAQGQQMIFPYYGHEEELRKHPIKRSTVGWATSSLLPGTSGGRQRRELDPMDIRGSIVYLEIDNRQCVQSSSQCFQSATDVAAFLGALASLGS-LNIPYKIEAVKSEPVEPPLPSQLHLMYV---AAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASD--GALMDDNQNEWGDEDLETKKFRFEEPVVLPDLSDQTDHRQWTQQHLD------AADLRMSAMAPTPPQGEVDADCMDV----NVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADA-QGVFQILLRNRATDLDARMH-------------------DGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANK---DMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRL---PRDIAQERMHHDIVRLLDE 2105 HSP 2 Score: 95.9005 bits (237), Expect = 3.128e-19 Identity = 81/276 (29.35%), Postives = 114/276 (41.30%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN------------IKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFAC 1111
+++ C + PCVNG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ PC C+N G C ES + F C C G+ G+ C V C P + C N N + C C GYTG C+ + C+ + C NGG C N + C+C F G C + E N P FN I + +P ++ C F G C N+F C
Sbjct: 752 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGASCQNT-------NGSYRCLCQAGYTGRNCESDID-----DCRPNPCHNGGSCTDGIN-TAFCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCPVGFNG---IHCENNTPDCTESSC---FNGGTCVDGINSFTC 1007 HSP 3 Score: 95.5153 bits (236), Expect = 3.551e-19 Identity = 71/216 (32.87%), Postives = 100/216 (46.30%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C ++PC +G + D + C C G G CE N++DC NPC + GTC+DK + + C C + G++C + C C NGGTCE G F C+C G+ C + C P I HG C N C C PG++G CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 607 CHSQPCRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPC-DSGTCLDKIDG-YECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAG-FTCRCPEGYHDPTCLSEVNECNSNPCI----------HGACRDGLN-GYKCDCAPGWSGTNCDINNNE-----CESNPCVNGGTCKDMTSGY-VCTCREGFSGPNCQTNINECASNPCLN 802 HSP 4 Score: 91.6633 bits (226), Expect = 5.334e-18 Identity = 72/215 (33.49%), Postives = 98/215 (45.58%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C++ PC++G C + + ++C C GW G C+ N N+C NPC NGGTC D S + C C F G CQ N C + C N GTC G ++C C + G C V C P C N G C + F C C G+ G C+ V+I C C +G C+ NGS C C+ +TG+NC + + R N
Sbjct: 720 CNSNPCIHGACRDGLN-GYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMT-SGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAG-YKCNCPLPYTGATCEVVLAPCATSP------CKNSGVCKESEDYESFSCVCPTGWQGQTCE------VDINECVKSPCRHGASCQNT-NGSYRCLCQAGYTGRNCESDIDDCRPNPCHN 918 HSP 5 Score: 88.1965 bits (217), Expect = 7.678e-17 Identity = 68/209 (32.54%), Postives = 94/209 (44.98%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF---ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
CS PC NG C D C+C G+ G+ CEENV+DC N CKNGG C+D N+ + C C ++ G C E + C+NGGTC + G + C C G+ GE C+ C + C++ + +C+C G TG C + C S+ C G C NG IC C +TG C+ + E
Sbjct: 222 CSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNT-YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGG-YNCVCVNGWTGEDCSENIDDCASAACFQGATCHDR-------VASFYCECPHGRTGLLCH------LNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDE 415 HSP 6 Score: 85.5001 bits (210), Expect = 4.555e-16 Identity = 67/206 (32.52%), Postives = 89/206 (43.20%), Query Frame = 2
Query: 332 SKLCSNRPCVNGKCVEAFDP----EFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
S C + PC N D ++ CSC G+ G C + N C+ NPC+NGGTC +++ C C + G CQ +PC + C NGG C E+ + C+C GF G C C P R H E Y C C +TG C ELP + C C NGG C+ + + C C F G+NC
Sbjct: 60 SNPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFES-SYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSY-----RCACRATHTGPHC----ELPY-VPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNC 254 HSP 7 Score: 83.1889 bits (204), Expect = 2.321e-15 Identity = 57/168 (33.93%), Postives = 77/168 (45.83%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAVQ-NIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRK 961
C NGG C + N C C+ F+G CQ NPCL+ C+N GTC +++G + C C GF G C + AC P C N G CD+ C+C PG++G C + C S+ C NGG C ++ S IC C F G C + E +
Sbjct: 31 CLNGGRC-EVANGTEACVCSGAFVGQRCQDSNPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLANP------CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADP------CASNPCANGGQCLPFES-SYICRCPPGFHGPTCRQDVNECSQ 184 HSP 8 Score: 82.4185 bits (202), Expect = 3.818e-15 Identity = 65/201 (32.34%), Postives = 95/201 (47.26%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC--IDKKNS-QFTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
C+NG E + C C + G+ C+++ N C+ PCKN GTC +D + + C+C F G LC +N CL C NGGTC+ L ++C+C G+ G+ C Q C P C N G+C + + C+C PG+ G C + E C +GG C + GS C C+ TG +C +P
Sbjct: 31 CLNGGRCEVANGTEACVCSGAFVGQRCQDS-NPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNP------CANGGQCLPF-ESSYICRCPPGFHGPTCRQDVN---ECSQNPGLCRHGGTCHN-EIGSYRCACRATHTGPHCELP 218 HSP 9 Score: 71.633 bits (174), Expect = 8.433e-12 Identity = 66/241 (27.39%), Postives = 93/241 (38.59%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP----------------------------------------CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C++ PC NG F+ + C C G+ G TC ++VN+C QNP C+NGGTC ++ C C F G C+ + C NC+NGG C N + C+C + G++C C ++P C N G C + C C G+TG+ C + + C S CF G C S CEC TG C +
Sbjct: 144 CASNPCANGGQCLPFESSYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVN-TYNCRCPPEWTGQYCTEDVDECQLMPNA----CQNGGTCHNT-HGGYNCVCVNGWTGEDCSENID-----DCASAACFQGATCHDR-VASFYCECPHGRTGLLCHL 372
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Notch2 (notch 2 [Source:MGI Symbol;Acc:MGI:97364]) HSP 1 Score: 156.377 bits (394), Expect = 1.076e-37 Identity = 132/426 (30.99%), Postives = 199/426 (46.71%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP-CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC-----TIPLKE------TRKEALINIKIPKTFNEK--QLIIKKTKSP-SLCDN-LCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSS--CKFHK-CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTV 1528
C N+PC NG C++ + F+CSC G +G CEEN+++C P C NGG C+D+ +TC C F G C+ + N CL+ C + G+ C L+N + C CR F G C CP P C N G C + NM C+C PG++G RC C C G C D+G P C C K+C + P + R+ + + P +F +L T +P + C + C +GICD+ CN+ AC +DGGDC DPW C C N+ C+ +CN +CLFD +C ++S CK+ K C++ +++ CD+ CNS +CG+DG DC + + + EG L +V++ + + FL+ L + L + +
Sbjct: 1191 CQNQPCQNGGTCIDLVN-HFKCSCPPGTRGLLCEENIDECAGGPHCLNGGQCVDRIGG-YTCRCLPGFAGERCEGDINECLSNPCSSEGSLDCVQLKNN-YNCICRSAFTGRHCETFLDVCPQKP------CLNGGTCAVASNMPDGFICRCPPGFSGARCQSS--------CGQVKCRRGEQCIHTDSG-PRCFC---LNPKDCESGCASNPCQHGGTCYPQRQPPHYSCRCPPSFGGSHCELYTAPTSTPPATCQSQYCADKARDGICDEACNSHACQWDGGDCSLTMEDPWANC--TSTLRCWEYINN-QCDEQCNTAECLFDNFECQRNSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCASDQPENLA--EGT-----------LIIVVLLPPEQLLQDSRSFLRALGTLLHTNLRI 1579 HSP 2 Score: 105.145 bits (261), Expect = 4.954e-22 Identity = 82/250 (32.80%), Postives = 114/250 (45.60%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICD 1087
C ++PC+N + C C G+ G CEE++NDC+ NPC+NGG+C+D N+ F+C C FIG+ CQ + N CL+ C+NGGTC N + C C GF G C I + C N G C N + C C G+TG C C S+ C N G C V G+ C C +TGKNC + L+N+ K +++ P LC ++ CD
Sbjct: 877 CISKPCMNNGVCHNTQGSYVCECPPGFSGMDCEEDINDCLANPCQNGGSCVDHVNT-FSCQCHPGFIGDKCQTDMNECLSEPCKNGGTCSDYVNS-YTCTCPAGFHGVHCENN------IDECTESSCFNGGTCVDGIN-SFSCLCPVGFTGPFCLHDINE-----CSSNPCLNAGTC-VDGLGTYRCICPLGYTGKNC---------QTLVNLCSRSPCKNKGTCVQEKARPHC---LCPPGWDGAYCD 1099 HSP 3 Score: 98.9821 bits (245), Expect = 3.467e-20 Identity = 102/369 (27.64%), Postives = 146/369 (39.57%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ--FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP--ICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCH---------KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKC 1405
C++ PC +G F +RC C G++G CE V++C PC+NGGTCID N F C+C G LC+ + +C NGG C G + C+C GF GE C C P C++ G D + C C +TG C+ ++ C C NGG C V N IC C F+G C + K +Q I + C N C+ C + C + GG C P R+ C+ C P F G C ++C+ C++ ++ ICDE CNS C +DGGDC + + + + +C
Sbjct: 1153 CASNPCQHGATCNDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVN-HFKCSCPPGTRGLLCEENIDECAGGPHCLNGGQCVDRIGG-YTCRCLPGFAGERCEGDINECLSNP------CSSEGSLDCVQLKNNYNCICRSAFTGRHCETFLDV-----CPQKPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQV-----------KCRRGEQCIHTDSGPRCFCLN-------PKDCESGCASNPCQH-GGTCYPQRQ---PPHYSCR-------CPPS-------FGGSHCELYTAPTSTPPATCQSQYCADKARDGICDEACNSHACQWDGGDCSLTMEDPWANCTSTLRC 1472 HSP 4 Score: 95.1301 bits (235), Expect = 4.670e-19 Identity = 71/200 (35.50%), Postives = 94/200 (47.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PC++G C ++C C GW G CE + N+C+ NPC+NGGTC + N + C C F G CQ + C + C N GTC +G + C C + G+ C Q + P P C N C PN F C C PG+ G RC + C S C N GVC GS +CEC F+G +C
Sbjct: 724 CLSNPCIHGNCTGGLS-GYKCLCDAGWVGVNCEVDKNECLSNPCQNGGTCNNLVNG-YRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDVSG-YTCHCMLPYTGKNC--QTVLAPCSPNP----CENAAVCKEAPNFESFSCLCAPGWQGKRCTVDVDE-----CISKPCMNNGVCHNT-QGSYVCECPPGFSGMDC 908 HSP 5 Score: 94.7449 bits (234), Expect = 7.244e-19 Identity = 67/235 (28.51%), Postives = 118/235 (50.21%), Query Frame = 2
Query: 2243 DEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D YQ +SL+ + GE +H+AAR + + ++A + ++ D GR PL +++AADA + Q+LI + +++ N TT LI A +L + M++ L++ + VN +D G+S +HW+A NN +E + D++DN++++PLFLAA EG+ ++ K LL +F I MD P+ +A ++ ++I L+ E
Sbjct: 1862 DLVYQGASLQA---QTDRTGEMALHLAARYSRADAAKRLLDAG--ADANAQDNMGRCPLHAAVAADA-QGVFQILIRNRVTDLDARMND-------------------GTTPLILAARLAVEGMVAELINCQADVNAVDDHGKSALHWAAAVNN---VEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANRDITDHMDRL---PRDVARDRMHHDIVRLLDE 2065 HSP 6 Score: 88.5817 bits (218), Expect = 4.931e-17 Identity = 69/219 (31.51%), Postives = 96/219 (43.84%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
V C + PC NG +RC+C G+KG C+ N+++C NPC N GTC D S +TC+C + G CQ PC CEN C+ N F C C G+ G+ C V C P +C+N + C+C PG++G C++ C ++ C NGG C V + C+C F G C + E E N
Sbjct: 756 VDKNECLSNPCQNGGTCNNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDV-SGYTCHCMLPYTGKNCQTVLAPCSPNPCENAAVCKEAPNFESFSCLCAPGWQGKRCTVDVDECISKPCMNNGVCHNT-------QGSYVCECPPGFSGMDCEEDIN-----DCLANPCQNGGSC-VDHVNTFSCQCHPGFIGDKCQTDMNECLSEPCKN 960 HSP 7 Score: 87.8113 bits (216), Expect = 9.933e-17 Identity = 70/217 (32.26%), Postives = 101/217 (46.54%), Query Frame = 2
Query: 350 RPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKN-SQFTCNCTSQFIGNLCQF--ENPC-LNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDK---KKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
PCVN G CV + C C G+ GE C+ + C +N C+NGGTC+ + + TC C F G CQ+ +PC ++ C+NGGTC L ++C C+ GF G+ C + AC P + C + CKC G TG +C+ + ++P C +GG C L GS C+C FTG++C P +N
Sbjct: 33 EPCVNEGTCVTYHNGTGFCRCPEGFLGEYCQHR-DPCEKNRCQNGGTCVPQGMLGKATCRCAPGFTGEDCQYSTSHPCFVSRPCQNGGTCHMLSRDTYECTCQVGFTGKQCQWTD-ACLSHPCENGSTCTSVAS-------QFSCKCPAGLTGQKCEADINECDIP-------GRCQHGGTCLNLP-GSYRCQCPQGFTGQHCDSPYVPCAPSPCVN 232 HSP 8 Score: 87.0409 bits (214), Expect = 1.392e-16 Identity = 68/209 (32.54%), Postives = 97/209 (46.41%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCL--NVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
C+ PCVNG C + D F C+C G++G TCE N++DC + C+NGG C+D N+ + C C Q+ G C + + CL C+NGGTC + NG + C C G+ G+ C+ C C I + C C G G C ++ C S+ C G +C NG IC C + G +CT + E
Sbjct: 225 CAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHKCQNGGVCVDGVNT-YNCRCPPQWTGQFCTEDVDECLLQPNACQNGGTCTN-RNGGYGCVCVNGWSGDDCSENIDDCAYASCTPGSTC-------IDRVASFSCLCPEGKAGLLCH------LDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDE 418 HSP 9 Score: 86.6557 bits (213), Expect = 1.984e-16 Identity = 64/193 (33.16%), Postives = 88/193 (45.60%), Query Frame = 2
Query: 365 GKCV-EAFDPEFRCSCWHGWKGETCEENV-NDC-IQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
G CV + + C C G+ GE C+ + + C + PC+NGGTC + C C F G CQ+ + CL+ CENG TC S+ + F CKC G G+ C C IP + C + G C P + C+C G+TG CD + C C NGG C+ + + C C F G C
Sbjct: 77 GTCVPQGMLGKATCRCAPGFTGEDCQYSTSHPCFVSRPCQNGGTCHMLSRDTYECTCQVGFTGKQCQWTDACLSHPCENGSTCTSVAS-QFSCKCPAGLTGQKCEADINECD-IPGR----CQHGGTCLNLPG-SYRCQCPQGFTGQHCDSPY-----VPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTC 257 HSP 10 Score: 86.2705 bits (212), Expect = 2.950e-16 Identity = 70/205 (34.15%), Postives = 92/205 (44.88%), Query Frame = 2
Query: 365 GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
GKCV D F C C G+ G CE ++N+C +PC+N TC+DK FTC C F G C+ E N C + C N G C N FQC C GF G C + C P C N +C +PN C+C G+TG CD+ + C D C +G +D S C C + G C+ + E +N
Sbjct: 431 GKCVNT-DGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGG-FTCLCMPGFKGVHCELEVNECQSNPCVNNGQCVDKVN-RFQCLCPPGFTGPVCQIDIDDCSSTP------CLNGAKCIDHPN-GYECQCATGFTGILCDENID-----NCDPDPCHHGQCQDGID--SYTCICNPGYMGAICSDQIDECYSSPCLN 618 HSP 11 Score: 85.5001 bits (210), Expect = 3.998e-16 Identity = 65/210 (30.95%), Postives = 95/210 (45.24%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDN-GSPICECKGEFTGKNCTIPLKETRKEALIN 976
C NG + + C C +GW G+ C EN++DC C G TCID+ S F+C C G LC ++ C++ C G C++ NG + C C G+ G C C + C + G+C + + C+C GY G RC+ ++I C SD C N C LD G C C F G +C + + E + +N
Sbjct: 309 CQNGGTCTNRNGGYGCVCVNGWSGDDCSENIDDCAYASCTPGSTCIDRVAS-FSCLCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAM---ANSNPCEHAGKC-VNTDGAFHCECLKGYAGPRCE------MDINECHSDPCQNDATC--LDKIGGFTCLCMPGFKGVHCELEVNECQSNPCVN 505 HSP 12 Score: 76.6406 bits (187), Expect = 2.109e-13 Identity = 55/167 (32.93%), Postives = 69/167 (41.32%), Query Frame = 2
Query: 461 QNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMF---QCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
Q PC N GTC+ N C C F+G CQ +PC C+NGGTC + GM C+C GF GE C P C N G C + T C C G+TG +C C S C NG C + + C+C TG+ C + E
Sbjct: 32 QEPCVNEGTCVTYHNGTGFCRCPEGFLGEYCQHRDPCEKNRCQNGGTC--VPQGMLGKATCRCAPGFTGEDCQYSTSH----PCFVSRPCQNGGTCHMLSRDTYECTCQVGFTGKQCQWTD------ACLSHPCENGSTCTSVASQF-SCKCPAGLTGQKCEADINE 185
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Notch3 (notch 3 [Source:MGI Symbol;Acc:MGI:99460]) HSP 1 Score: 132.109 bits (331), Expect = 2.962e-30 Identity = 117/414 (28.26%), Postives = 175/414 (42.27%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGT--CIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCE-SLENG---MFQCKCRYGFIGEFC-----AVQNIACPV-IPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELP---VEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKS----SCK--FHK-CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLR 1513
NG CV+ FRC+C G+ G CE ++N+C C T C+ F C C F G CQ +PC + C++GG C SL G F C C F G C + + + CPV IP ++ C C PG +G C + P C S C +GG C + + P C C + G C P E + P+ C+A + CD++CNT C +DGGDC DPWR+C + C +FN+ C+P C++ CL+D DC+ +C + K C++ + + CD+ CN+ +CG+DG DC S + + L L ++ + + ++FLQ+LS+ LR
Sbjct: 1180 NGTCVDLVG-GFRCNCPPGYTGLHCEADINECRPGACHAAHTRDCLQDPGGHFRCVCHPGFTGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTCHCVPPFWGLRCERVARSCRELQCPVGIPCQQTA-------------RGPRCACPPGLSGPSCRVSRASPSGATNASCASAPCLHGGSCLPVQS-VPFFRCVCAPGWGGPRCETP--SAAPEVPEEPRCPRA-------------------ACQAKRGDQNCDRECNTPGCGWDGGDCSLNVDDPWRQC---EALQCWRLFNNSRCDPACSSPACLYDNFDCYSGGRDRTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDC-ASEVPALLARGVLV------------LTVLLPPEELLRSSADFLQRLSAILR 1541 HSP 2 Score: 97.0561 bits (240), Expect = 1.320e-19 Identity = 95/334 (28.44%), Postives = 129/334 (38.62%), Query Frame = 2
Query: 317 LVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENV--NDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE-----------TRKEALINIKIPKTFNEKQLIIKKTK-SPSLCDNLCKASFENGICDQQCNTFAC----NYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCL----FDGEDCH 1252
L + ++ C+++PC +G C +A FRC C GW G C +++ + C PC+ GGTC F C C F G+ C+ +PC CE+GG CES + + C C G+ G C C C HG C P C C GYTG CD+ + C + C +GG C+ GS C C F G C + E T A P + I SPS C F G C ++F+C Y G C Y D + + G+CNP +C F G C
Sbjct: 692 LCLPANHPCAHKPCSHGVCHDAPG-GFRCVCEPGWSGPRCSQSLAPDACESQPCQAGGTCT-SDGIGFRCTCAPGFQGHQCEVLSPCTPSLCEHGGHCESDPDRLTVCSCPPGWQGPRCQQDVDEC-----AGASPCGPHGTCTNLPG-NFRCICHRGYTGPFCDQDID-----DCDPNPCLHGGSCQD-GVGSFSCSCLDGFAGPRCARDVDECLSSPCGPGTCTDHVASFTCACPPGYGGFHCEIDLPDCSPSSC-------FNGGTCVDGVSSFSCLCRPGYTGTHCQ-----YEADPCFSRPCLHGGICNPTHPGFECTCREGFTGSQCQ 999 HSP 3 Score: 83.9593 bits (206), Expect = 1.437e-15 Identity = 92/312 (29.49%), Postives = 137/312 (43.91%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC-LNVN-CENGGTCESLENGMFQCKCRYGFIGEFCAVQNI-----------------------ACPVIPKKKREL------------CNNHGECDIYP-NMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE-----TRKEALINIKIPKTFNEKQLIIKKTKSPSLCD---NLCKAS--FENGICDQQCNTFACNYDGG 1126
C+ PC NG C ++ D + C+C G++G+ CE NV+DC + C NGGTC+D N+ + C C ++ G C + + C L N C NGGTC +L G C C G+ GE C+ QNI ACP+ K L C+ CD P + C C PG+TG CD+ + E ++ C + G C V GS +C+C +TG C + E R +A +I + I + + C+ + C++S G+C + N F+C G
Sbjct: 202 CAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNT-YNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNLLGG-HSCVCVNGWTGESCS-QNIDDCATAVCFHGATCHDRVASFYCACPM---GKTGLLCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTGGACDQDVD---ECSIGANPCEHLGRC-VNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRI----GQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSG 499 HSP 4 Score: 83.1889 bits (204), Expect = 2.049e-15 Identity = 60/185 (32.43%), Postives = 87/185 (47.03%), Query Frame = 2
Query: 395 FRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL 946
FRC C G+ G C+++++DC NPC +GG+C D S F+C+C F G C + + CL+ C G + + + F C C G+ G C + +P C N G C + + C C PGYTG C + + C S C +GG+C G C C+ FTG C P+
Sbjct: 834 FRCICHRGYTGPFCDQDIDDCDPNPCLHGGSCQDGVGS-FSCSCLDGFAGPRCARDVDECLSSPCGPGTCTDHVAS--FTCACPPGYGGFHCEID------LPDCSPSSCFNGGTC-VDGVSSFSCLCRPGYTGTHCQYEADP-----CFSRPCLHGGICNPTHPGF-ECTCREGFTGSQCQNPV 1002 HSP 5 Score: 82.0333 bits (201), Expect = 5.317e-15 Identity = 64/213 (30.05%), Postives = 90/213 (42.25%), Query Frame = 2
Query: 353 PCVNGKCVEAFDP--EFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC---IDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
PC NG P E C C GW GE C+ + C PC G C + ++F+C C F G C +PC++ C +G C +G F C C G+ G+ C C + C + G C P + C+C GYTG C E PV + C C NGG C+ + + C C F G+NC + + + +N
Sbjct: 48 PCANGGRCTHQQPSLEAACLCLPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAGTARFSCRCLRGFQGPDCSQPDPCVSRPCVHGAPCSVGPDGRFACACPPGYQGQSCQSDIDEC-----RSGTTCRHGGTCLNTPG-SFRCQCPLGYTGLLC----ENPV-VPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLN 248 HSP 6 Score: 80.4925 bits (197), Expect = 1.579e-14 Identity = 60/224 (26.79%), Postives = 110/224 (49.11%), Query Frame = 2
Query: 2276 LGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIK--MDPNCPCPKLIAEEKGFYEIRDLIQE 2941
LG + GE+ +H+AAR + ++A + ++ D GRTPL +++ ADA + Q+LI + +++ +TALI A +L + M+ L+ + VN +D G+S +HW+A NN +E + D++D+++++PLFLAA EG+ ++ K LL + I +D P+ +A+E+ +I L+ +
Sbjct: 1832 LGARTDRTGETALHLAARYARADAAKRLLDAG--ADTNAQDHSGRTPLHTAVTADA-QGVFQILIRNRSTDLDAR-------------------MADGSTALILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNN---VEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHLANREITDHLDRL---PRDVAQERLHQDIVRLLDQ 2027 HSP 7 Score: 78.1814 bits (191), Expect = 8.115e-14 Identity = 83/334 (24.85%), Postives = 126/334 (37.72%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFC--AVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN-----IKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFN----DGVCNPECNNVDCLFDGEDCHKSSCKFHKCSELYQNKIC 1306
C++ PC G C + + + C C G+ G C +N+C +PC GG+C+D +N F C C + LC N PC + C + G C G F+C C G+ G C ++ AC P + C + G + C C PG+ G +C+ V C C +GG C+ + +C C + G C + E + +P F +C + CDQ D DCDP +G + G F+ DG P C D ++C S C C++ + C
Sbjct: 625 CASNPCTFGVCRDGIN-RYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENG-FHCLCPPGSLPPLCLPANHPCAHKPCSH-GVCHDAPGG-FRCVCEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDG-------IGFRCTCAPGFQGHQCE------VLSPCTPSLCEHGGHCESDPDRLTVCSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGNFR----------------CICHRGYTGPFCDQ---------DIDDCDPNPCLHGGSCQDGVGSFSCSCLDGFAGPRCAR-----DVDECLSSPCGPGTCTDHVASFTC 911 HSP 8 Score: 73.9442 bits (180), Expect = 1.581e-12 Identity = 64/214 (29.91%), Postives = 93/214 (43.46%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ------FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC----DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C + PCVNG + F C+C G+ G C+ +V++C PC+NG C+D+ + + C C F G LC+ +PC + C +G F C C G+ G C Q C + + C G+C D Y C+C PG TG C+ + C S+ C GVC+ N C C+ FTG C + + E
Sbjct: 474 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVDECASTPCRNGAKCVDQPDG-YECRCAEGFEGTLCERNVDDCSPDPCHHGRCVDG-------IASFSCACAPGYTGIRCESQVDEC------RSQPCRYGGKCLDLVDKY-----LCRCPPGTTGVNCEVNID-----DCASNPC-TFGVCRDGINRY-DCVCQPGFTGPLCNVEINE 661 HSP 9 Score: 71.633 bits (174), Expect = 7.037e-12 Identity = 59/189 (31.22%), Postives = 80/189 (42.33%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PC----------LNVNCENGGTCESLENGMFQ-CKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC 871
C +RPC++G P F C+C G+ G C+ V+ C Q PC+NGG C+ + C C + G LC ++ PC L C+ GG C ++ G C C G G C + C P C + G C Y C+C GY GD C+ + C S C NGG C
Sbjct: 967 CFSRPCLHGGICNPTHPGFECTCREGFTGSQCQNPVDWCSQAPCQNGGRCV---QTGAYCICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQLCQEGGKC--IDKGRSHYCVCPEGRTGSHCEHEVDPCTAQP------CQHGGTCRGY-MGGYVCECPAGYAGDSCEDNIDE-----CASQPCQNGGSC 1138 HSP 10 Score: 71.2478 bits (173), Expect = 8.762e-12 Identity = 52/161 (32.30%), Postives = 74/161 (45.96%), Query Frame = 2
Query: 395 FRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC 871
FRC C G+ G CE V C +PC+NGGTC + + C C F G C+ + C C NGGTC N + C+C + G+FC C + P C+N G C ++ + C C G+TG+ C + + C + CF+G C
Sbjct: 182 FRCQCPLGYTGLLCENPVVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVN-TYNCQCPPEWTGQFCTEDVDECQLQPNA----CHNGGTCFNLLGGHS--CVCVNGWTGESCSQNID-----DCATAVCFHGATC 330 HSP 11 Score: 68.5514 bits (166), Expect = 6.746e-11 Identity = 51/166 (30.72%), Postives = 75/166 (45.18%), Query Frame = 2
Query: 464 NPCKNGGTCIDKKNS-QFTCNCTSQFIGNLCQFENPCLNVNCENGGTCES---LENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSD-YCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL 946
+PC NGG C ++ S + C C ++G CQ E+PC + C G C+S F C+C GF G C+ + P + + C + C + P+ C C PGY G C + C+S C +GG C + GS C+C +TG C P+
Sbjct: 47 SPCANGGRCTHQQPSLEAACLCLPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCLRGFQGPDCSQPD---PCVSRP----CVHGAPCSVGPDGRFACACPPGYQGQSCQSDIDE-----CRSGTTCRHGGTC-LNTPGSFRCQCPLGYTGLLCENPV 199
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Notch4 (notch 4 [Source:MGI Symbol;Acc:MGI:107471]) HSP 1 Score: 117.087 bits (292), Expect = 9.790e-26 Identity = 121/437 (27.69%), Postives = 171/437 (39.13%), Query Frame = 2
Query: 284 FPMNVFILGCLLVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLC-QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP--ICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQ-LIIKKTKSPSLCDNL-------------------CKASFENGICDQ---------QC--------------NTFACNYDGGD--CD---------------------PWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCH-KSSCKF---HKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNS 1375
FP++ I S LC N G C++ F C C G++G+ C++NVN C NPC +G TC+ + S + C C + G C + + C + C N GTC S G F C C GF+G C C P H + + +C+C PG+TG RC+ + +L C+S C NGG C++ P C C F G C+ ++ I N L K SP LC L NG C + QC C GGD CD PW+ C + C +F DG C+P+C++ +CLFDG DC +C C + + N C++ CN+ +CG+DGGDC +S
Sbjct: 878 FPLSCQKAAMSQGIEISGLCQN----GGLCIDTGSSYF-CRCPPGFQGKLCQDNVNPCEPNPCHHGSTCVPQP-SGYVCQCAPGYEGQNCSKVLDACQSQPCHNHGTCTSRPGG-FHCACPPGFVGLRCEGDVDECLDRPCHPSGTAACHSLANAF-----YCQCLPGHTGQRCEVEMDL-----CQSQPCSNGGSCEITTGPPPGFTCHCPKGFEGPTCS--------HKALSCGIHHCHNGGLCLPSPKPGSPPLCACLSGFGGPDCLTPPAPPGCGPPSPCLHNGTCTETPGLGNPGFQCTCPPDSPGPRCQRPGASGCEGRGGDGTCDAGCSGPGGDWDGGDCSLGVPDPWKGCPPH--SQCWLLFRDGRCHPQCDSEECLFDGYDCEIPLTCIPAYDQYCRDHFHNGHCEKGCNNAECGWDGGDCRPEGEDS 1287 HSP 2 Score: 91.2781 bits (225), Expect = 7.388e-18 Identity = 71/199 (35.68%), Postives = 90/199 (45.23%), Query Frame = 2
Query: 353 PCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL 946
PC +G F C C G+ G CE + N+C+ PC G TC+D + F C C G LC+ E N C + C N C L NG FQC C GF G C C P C N G C P +C+C PG+ G C+K+ + C SD C G C L G+ C C+ FTG+ C +PL
Sbjct: 442 PCEHGGSCINTPGSFNCLCLPGYTGSRCEADHNECLSQPCHPGSTCLDLL-ATFHCLCPPGLEGRLCEVEVNECTSNPCLNQAACHDLLNG-FQCLCLPGFTGARCEKDMDECSSTP------CANGGRCRDQPG-AFYCECLPGFEGPHCEKEVDE-----CLSDPCPVGASCLDLP-GAFFCLCRPGFTGQLCEVPL 625 HSP 3 Score: 81.2629 bits (199), Expect = 9.299e-15 Identity = 55/171 (32.16%), Postives = 75/171 (43.86%), Query Frame = 2
Query: 467 PCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVN-CENGGTCESLENGM-------------FQCKCRYGFIGEFCAVQ-NIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
PC NGGTC+ Q C C F+G CQF +PC + C+NGG+C++L F C C GF G+ C CP C+N G C + + C C+PG+TG++C + C ++ C NGGVC + C C F G C
Sbjct: 31 PCANGGTCLRLSRGQGICQCAPGFLGETCQFPDPCRDTQLCKNGGSCQALLPTPPSSRSPTSPLTPHFSCTCPSGFTGDRCQTHLEELCPP------SFCSNGGHCYVQASGRPQCSCEPGWTGEQCQLRDF------CSANPCANGGVC-LATYPQIQCRCPPGFEGHTC 188 HSP 4 Score: 80.8777 bits (198), Expect = 1.029e-14 Identity = 70/233 (30.04%), Postives = 97/233 (41.63%), Query Frame = 2
Query: 317 LVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAV--------------------QNIACP-----VIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCT 937
L V C++ PC+N F+C C G+ G CE+++++C PC NGG C D+ + F C C F G C+ E + CL+ C G +C L G F C CR GF G+ C V CP +P + C +HG C C CD G+TG C+ + GC S C +GG C +G C C + G C+
Sbjct: 506 LCEVEVNECTSNPCLNQAACHDLLNGFQCLCLPGFTGARCEKDMDECSSTPCANGGRCRDQPGA-FYCECLPGFEGPHCEKEVDECLSDPCPVGASCLDLP-GAFFCLCRPGFTGQLCEVPLCTPNMCQPGQQCQGQEHRAPCLCPDGSPGCVPAEDNCPC-HHGHCQRS-----LCVCDEGWTGPECETELG-----GCISTPCAHGGTCHPQPSGY-NCTCPAGYMGLTCS 724 HSP 5 Score: 80.8777 bits (198), Expect = 1.239e-14 Identity = 64/271 (23.62%), Postives = 122/271 (45.02%), Query Frame = 2
Query: 2129 LAFQLISDSLESTDGIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINA-INPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLIQ 2938
L + ++ST G P GLG++ + + + + + GE+ +H+AAR + + + A NP+ D GRTPL +++AADA E QLL+ +Q +++ TT L+ A +L ++++ L+ + V D +G++ +HW+A NN+ L + D +D+ +++PLFLAA EGA++ + LL ++ D P +A ++ +++ L++
Sbjct: 1583 LMSAVFCGGVQSTTGASPQRLGLGNLEPWEPLLDRGACPQAHTVGT-----------GETPLHLAARFSRPTAARRLLEAGANPNQP---DRAGRTPLHTAVAADAREVC-QLLLASRQTTVDARTED-------------------GTTPLMLAARLAVEDLVEELIAARADVGARDKRGKTALHWAAAVNNARAARSLLQAGADK---DAQDSREQTPLFLAAREGAVEVAQLLLELGAARGLR-DQAGLAPGDVARQRSHWDLLTLLE 1815 HSP 6 Score: 78.5666 bits (192), Expect = 5.076e-14 Identity = 77/251 (30.68%), Postives = 102/251 (40.64%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQ-NIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI-CECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGIC 1084
C + PC +G + C+C G+ G TC E V C PC NGG+C + ++C C G CQ + C++ +C NGGTC + + G F C C GF G C + N +C P C N C P C C PGYTG C +L C C + C L +G C C +TG C PL + I+I L I T S C C F+ +C
Sbjct: 692 CISTPCAHGGTCHPQPSGYNCTCPAGYMGLTCSEEVTACHSGPCLNGGSCSIRPEG-YSCTCLPSHTGRHCQTAVDHCVSASCLNGGTCVN-KPGTFFCLCATGFQGLHCEEKTNPSCADSP------CRNKATCQDTPRGAR-CLCSPGYTGSSCQTLIDL-----CARKPCPHTARC--LQSGPSFQCLCLQGWTGALCDFPLSCQKAAMSQGIEISGLCQNGGLCI-DTGSSYFCR--CPPGFQGKLC 923 HSP 7 Score: 78.5666 bits (192), Expect = 5.295e-14 Identity = 65/208 (31.25%), Postives = 86/208 (41.35%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C NG + F C C GW G CEEN++DC C G TCID+ S F+C C G LC E+ CL+ C C + G C C+ G+ G C C + ++ C + G C P + C C PGYTG RC+ C S C G C L + C C G+ C + + E +N
Sbjct: 323 CRNGGTCQNTAGSFHCVCVSGWGGAGCEENLDDCAAATCAPGSTCIDRVGS-FSCLCPPGRTGLLCHLEDMCLSQPCHVNAQCSTNPLTGSTLCICQPGYSGSTCHQDLDEC-QMAQQGPSPCEHGGSCINTPG-SFNCLCLPGYTGSRCEADHNE-----CLSQPCHPGSTCLDL-LATFHCLCPPGLEGRLCEVEVNECTSNPCLN 521 HSP 8 Score: 69.3218 bits (168), Expect = 3.292e-11 Identity = 54/156 (34.62%), Postives = 67/156 (42.95%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCD 805
C ++PC G F C C G +G CE VN+C NPC N C D N F C C F G C+ + + C + C NGG C + G F C+C GF G C + C P C C P FC C PG+TG C+
Sbjct: 476 CLSQPCHPGSTCLDLLATFHCLCPPGLEGRLCEVEVNECTSNPCLNQAACHDLLNG-FQCLCLPGFTGARCEKDMDECSSTPCANGGRCRD-QPGAFYCECLPGFEGPHCEKEVDECLSDP------CPVGASCLDLPG-AFFCLCRPGFTGQLCE 622 HSP 9 Score: 69.3218 bits (168), Expect = 3.434e-11 Identity = 75/267 (28.09%), Postives = 103/267 (38.58%), Query Frame = 2
Query: 317 LVIVSSKLC--SNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCE--ENVNDCIQNPCKNGGTC-------------IDKKNSQFTCNCTSQFIGNLCQ--FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKK-KELPVEIG----------------------------------CKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCTI 940
+++ LC S PC NG C+ + C C G+ GETC+ + D CKNGG+C F+C C S F G+ CQ E C C NGG C +G QC C G+ GE C +++ C P C N G C YP + C+C PG+ G C++ E +E G C C NGG C+++ G +C C FTG +C +
Sbjct: 17 VILTRELLCGGSPEPCANGGTCLRLSRGQGICQCAPGFLGETCQFPDPCRD--TQLCKNGGSCQALLPTPPSSRSPTSPLTPHFSCTCPSGFTGDRCQTHLEELCPPSFCSNGGHCYVQASGRPQCSCEPGWTGEQCQLRDF-CSANP------CANGGVCLATYPQIQ--CRCPPGFEGHTCERDINECFLEPGPCPQGTSCHNTLGSYQCLCPVGQEGPQCKLRKGACPPGSCLNGGTCQLVPEGHSTFHLCLCPPGFTGLDCEM 272 HSP 10 Score: 64.3142 bits (155), Expect = 1.102e-9 Identity = 60/190 (31.58%), Postives = 78/190 (41.05%), Query Frame = 2
Query: 323 IVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVND-CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCL--NVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYP---NMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC 871
+ CSN G C +CSC GW GE C+ + D C NPC NGG C+ Q C C F G+ C+ + N C C G +C + G +QC C G G C ++ ACP C N G C + P + C C PG+TG C+ + C C NG C
Sbjct: 118 LCPPSFCSN----GGHCYVQASGRPQCSCEPGWTGEQCQ--LRDFCSANPCANGGVCL-ATYPQIQCRCPPGFEGHTCERDINECFLEPGPCPQGTSCHNTL-GSYQCLCPVGQEGPQCKLRKGACPP------GSCLNGGTCQLVPEGHSTFHLCLCPPGFTGLDCEMNPD-----DCVRHQCQNGATC 288 HSP 11 Score: 58.9214 bits (141), Expect = 5.386e-8 Identity = 63/209 (30.14%), Postives = 84/209 (40.19%), Query Frame = 2
Query: 338 LCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCI--QNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVNCENGGTCESLENG---MFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC----DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
CS PC NG A P+ +C C G++G TCE ++N+C PC G +C + S + C C G C+ + C +C NGGTC+ + G C C GF G C + C R C N C D Y C C + G C + + G C NGG C+ GS C C + G C
Sbjct: 156 FCSANPCANGGVCLATYPQIQCRCPPGFEGHTCERDINECFLEPGPCPQGTSCHNTLGS-YQCLCPVGQEGPQCKLRKGACPPGSCLNGGTCQLVPEGHSTFHLCLCPPGFTGLDCEMNPDDC------VRHQCQNGATCLDGLDTY-----TCLCPKTWKGWDCSEDIDECEARG--PPRCRNGGTCQNT-AGSFHCVCVSGWGGAGC 349
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Match: Sned1 (sushi, nidogen and EGF-like domains 1 [Source:MGI Symbol;Acc:MGI:3045960]) HSP 1 Score: 105.531 bits (262), Expect = 3.234e-22 Identity = 75/201 (37.31%), Postives = 104/201 (51.74%), Query Frame = 2
Query: 350 RPCVNG-KCVE---AFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
RPC+NG KC++ +P + CSC G+ G C +VN+C +PC+NGGTC NS F+C C + F G C+ ++PC N C+NGG C++ E+ C C+ G+ G C C P C N G C D+ N + C C + G +C+ L V C S+ C NGG C D G +CEC F G +C
Sbjct: 276 RPCLNGGKCIDDCVTGNPSYTCSCLAGFTGRRCHLDVNECASHPCQNGGTCTHGVNS-FSCQCPAGFKGPTCESAQSPCDNKVCQNGGQCQA-ESSSAVCVCQAGYTGATCETDVDECSSDP------CQNGGSCVDLVGNYS--CICVEPFEGPQCETGSYL-VPSPCLSNPCQNGGTCVDADEGY-VCECPEGFMGLDC 464 HSP 2 Score: 92.8189 bits (229), Expect = 2.450e-18 Identity = 77/241 (31.95%), Postives = 110/241 (45.64%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-----FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKREL----CNNHGECDIYPNMTLFCKCDPGY---------TGDRCDKKKELP-----VEIG--------------------CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C N+ C NG +A C C G+ G TCE +V++C +PC+NGG+C+D + ++C C F G C+ +PCL+ C+NGGTC + G + C+C GF+G C ++R L C N G C + N TL C+C PG+ T C+ + P +E G C SD CFNGG C ++ S CEC F G++C
Sbjct: 353 CDNKVCQNGGQCQAESSSAVCVCQAGYTGATCETDVDECSSDPCQNGGSCVDLVGN-YSCICVEPFEGPQCETGSYLVPSPCLSNPCQNGGTCVDADEG-YVCECPEGFMGLDC------------RERILNDCDCRNGGRC-LGANTTL-CQCPPGFFGLLCEFEVTATPCNMNTQCPDGGYCMEYGGSYLCVCHTDHNISHSLPSPCDSDPCFNGGSCDAHED-SYTCECPRGFHGRHC 576 HSP 3 Score: 82.8037 bits (203), Expect = 2.392e-15 Identity = 53/165 (32.12%), Postives = 81/165 (49.09%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEI 832
C ++PC++G + +++C C G++G CE ++C PC+NGG+C D + F C C F+G C+ E + C + C++GG CE G + C C GF G C + C P C + G C + N + C C GYTG C K+ P +
Sbjct: 757 CRSQPCLHGGSCQDLIADYQCLCSPGYEGVHCELETDECQAQPCRNGGSCRDLPRA-FICQCPEGFVGIHCETEVDACASSPCQHGGRCED-GGGAYLCVCPEGFFGYNCETVSDPCFSSP------CGSRGYC-LASNGSHSCTCKVGYTGKDCTKELLPPTAL 912 HSP 4 Score: 77.411 bits (189), Expect = 1.042e-13 Identity = 58/163 (35.58%), Postives = 74/163 (45.40%), Query Frame = 2
Query: 458 IQNPCKNGGTCID---KKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
+ PC NGG CID N +TC+C + F G C + N C + C+NGGTC N F C+C GF G C C ++C N G+C + + C C GYTG C+ + C SD C NGG C L G+ C C F G C
Sbjct: 274 VLRPCLNGGKCIDDCVTGNPSYTCSCLAGFTGRRCHLDVNECASHPCQNGGTCTHGVNS-FSCQCPAGFKGPTCESAQSPC------DNKVCQNGGQCQAE-SSSAVCVCQAGYTGATCETDVDE-----CSSDPCQNGGSCVDL-VGNYSCICVEPFEGPQC 422 HSP 5 Score: 75.485 bits (184), Expect = 4.986e-13 Identity = 66/239 (27.62%), Postives = 102/239 (42.68%), Query Frame = 2
Query: 335 KLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVND-CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKK---------ELP--VEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN----IKIPKTF 997
LCS+ PC NG + E+RC+C + + G CE D C PC NGGTC ++ C+C F G C+ +PC C NGGTCE L F C C+ G+ G C + + C + + +G + C+PG++ + + P +E+ C+S C +GG C+ L C C + G +C + E + + N +P+ F
Sbjct: 582 HLCSSGPCRNGGTCKEMGDEYRCTCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIG-KYKCDCPPGFSGRHCEIAPSPCFRSPCMNGGTCEDLGTD-FSCYCQPGYTGHRCQAE-VDCGHPEEVEHATMRFNG---THVGSVALYTCEPGFSLSALSHIRVCQPQGVWSQPPQCIEVDECRSQPCLHGGSCQDL-IADYQCLCSPGYEGVHCELETDECQAQPCRNGGSCRDLPRAF 813
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|G3I6Z6|NOTC1_CRIGR (Neurogenic locus notch homolog protein 1 OS=Cricetulus griseus OX=10029 GN=NOTCH1 PE=1 SV=2) HSP 1 Score: 201.445 bits (511), Expect = 1.158e-50 Identity = 236/1013 (23.30%), Postives = 388/1013 (38.30%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS---------------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL----------------KETRKEALINIKIPKTFNEKQLII----------KKTKSPSLCDNL----CKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTS---------------------RSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQ---KLSSSLRMVVTVFNVT-------EINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVN--ENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGR----------------------TPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
CS PC NG + F C C G+ G C E +N+C+ PC+NGGTCID N+ ++C C F+G C+ + N CL+ C+ GT + ++ F C+CR G G C VI + + C N G C + N C+C G+ G C+ C S C NGG C + SP C C G FTG C P + T + P FN I + P + + C+ N +C+ QCN AC +DGGDC DPW+ C C F+DG C+ +CN+ CLFDG DC ++ + + C + + + CD+ CNS +C +DG DC R+NSF L+ +++ D + + ++ E + K S+ ++ T E++ ++ L ++ QCV QCF S ++ FL A GN L++P+++ V + + +L + + A + GVLL K + ++ + S + G L D N+ +G+ +T + R PD ++R+ + ++ A L ++ T +DA DV +V+ + S G E N E ++ I+ + GA++ Q + + LH + R TPL ++++ADA + Q+L+ + +++ + TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL +F I MD P+ IA+E+ ++I L+ E
Sbjct: 1165 CSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCEINVDDCHPHLDPASRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDINECLSNPCDPRGTQDCVQRVNDFHCECRAGHTGRRCES------VINGCRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCENDART-----CGSLRCLNGGTC-ISGPRSPTCLCLGSFTGPECQFPASSPCVGSNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFTGGAGRDIPPPQIEEACELPECQEDAGNKVCNLQCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFSDGHCDSQCNSASCLFDGFDCQRTEGQCNPLYDQYCKDHFSDGHCDQGCNSAECDWDGLDCADHVPERLAAGTLVLVVLLPPEQLRNNSFHFLRELSHVLHTNVVFKRDAEGQQMIFPYYGHEEELRKHPIKRSAVGWTTSSLLPSTNGGRQRRELDPMDIRGSIVYLEIDNRQCVQSSSQCFQSATDVAAFLGALASLGN-LNIPYKIEAVKSETVEPPLPSQLHLMYL---AAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASD--GALMDDNQNEWGDEDLETKKFRFEEPVVVPDLDDQTDHRQWTQQHLD------AADLRMSAMAPTPPQGEVDADCMDV----NVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADA-QGVFQILLRNRATDLDARMH-------------------DGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANK---DMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRL---PRDIAQERMHHDIVRLLDE 2121 HSP 2 Score: 95.9005 bits (237), Expect = 2.169e-18 Identity = 71/216 (32.87%), Postives = 100/216 (46.30%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C ++PC +G + D + C C G G CE N++DC NPC + GTC+DK + + C C + G++C + C C NGGTCE G F C+C G+ C + C P I HG C N C C PG++G CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 623 CHSQPCRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPC-DSGTCLDKIDG-YECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAG-FTCRCPEGYHDPTCLSEVNECNSNPCI----------HGACRDGLN-GYKCDCAPGWSGTNCDINNNE-----CESNPCVNGGTCKDMTSGY-VCTCREGFSGPNCQTNINECASNPCLN 818 HSP 3 Score: 95.5153 bits (236), Expect = 2.866e-18 Identity = 80/276 (28.99%), Postives = 114/276 (41.30%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN------------IKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFAC 1111
+++ C + PCVNG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ PC C+N G C ES + F C C G+ G+ C + C P + C N N + C C GYTG C+ + C+ + C NGG C N + C+C F G C + E N P FN I + +P ++ C F G C N+F C
Sbjct: 768 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSPCRHGASCQNT-------NGSYRCLCQAGYTGRNCESDID-----DCRPNPCHNGGSCTDGINMA-FCDCLPGFQGAFCEEDINECASNPCRNGANCTDCVDSYTCTCPAGFNG---IHCENNTPDCTESSC---FNGGTCVDGINSFTC 1023 HSP 4 Score: 91.6633 bits (226), Expect = 4.725e-17 Identity = 71/215 (33.02%), Postives = 98/215 (45.58%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C++ PC++G C + + ++C C GW G C+ N N+C NPC NGGTC D S + C C F G CQ N C + C N GTC G ++C C + G C V C P C N G C + F C C G+ G C+ ++I C C +G C+ NGS C C+ +TG+NC + + R N
Sbjct: 736 CNSNPCIHGACRDGLN-GYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKD-MTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAG-YKCNCPLPYTGATCEVVLAPCATSP------CKNSGVCKESEDYESFSCVCPTGWQGQTCE------IDINECVKSPCRHGASCQNT-NGSYRCLCQAGYTGRNCESDIDDCRPNPCHN 934 HSP 5 Score: 88.1965 bits (217), Expect = 4.497e-16 Identity = 68/209 (32.54%), Postives = 96/209 (45.93%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC--LNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
CS PC NG C D C+C G+ G+ CEENV+DC N CKNGG C+D N+ + C C ++ G C + + C + C+NGGTC + G + C C G+ GE C+ C + C++ + +C+C G TG C + C S+ C G C NG IC C +TG C+ + E
Sbjct: 238 CSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNT-YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGG-YNCVCVNGWTGEDCSENIDDCASAACFQGATCHDR-------VASFYCECPHGRTGLLCH------LNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDE 431 HSP 6 Score: 84.3445 bits (207), Expect = 7.596e-15 Identity = 65/208 (31.25%), Postives = 89/208 (42.79%), Query Frame = 2
Query: 359 VNGKCVEAFDPEFRCSCWHGWKGET---CEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAVQ-NIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRK 961
+ G C + DP C H + C + C+ NGG C + N C C+ F+G CQ NPCL+ C+N GTC +E+G + C C GF G C + AC P C N G CD+ C+C PG++G C + C S+ C NGG C ++ S IC C F G C + E +
Sbjct: 12 LEGGCEQNIDPRRAAHCHHPRLATSSLRCSQPSGTCL-----NGGRC-EVANGTEACVCSGPFVGQRCQDPNPCLSTPCKNAGTCHVVEHGGTVNYACSCPLGFSGPLCLTPLDNACLANP------CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADP------CASNPCANGGQCLPFES-SYICGCPPGFHGPTCRQDVNECSQ 200 HSP 7 Score: 81.2629 bits (199), Expect = 6.868e-14 Identity = 61/181 (33.70%), Postives = 80/181 (44.20%), Query Frame = 2
Query: 395 FRCSCWHGWKGETCEENV-NDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
+ CSC G+ G C + N C+ NPC+NGGTC +++ C C + G CQ +PC + C NGG C E+ + C C GF G C C P R H E Y C C +TG C ELP + C C NGG C+ + + C C F G+NC
Sbjct: 101 YACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFES-SYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSY-----RCVCRATHTGPHC----ELPY-VPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNC 270 HSP 8 Score: 77.411 bits (189), Expect = 1.012e-12 Identity = 67/215 (31.16%), Postives = 99/215 (46.05%), Query Frame = 2
Query: 323 IVSSKLCSNRP---CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS---QFTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
+ +S L ++P C+NG E + C C + G+ C++ N C+ PCKN GTC ++ + C+C F G LC +N CL C NGGTC+ L ++C+C G+ G+ C Q C P C N G+C + + C C PG+ G C + E C +GG C + GS C C+ TG +C +P
Sbjct: 33 LATSSLRCSQPSGTCLNGGRCEVANGTEACVCSGPFVGQRCQD-PNPCLSTPCKNAGTCHVVEHGGTVNYACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNP------CANGGQCLPF-ESSYICGCPPGFHGPTCRQDVN---ECSQNPGLCRHGGTCHN-EIGSYRCVCRATHTGPHCELP 234
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|Q01705|NOTC1_MOUSE (Neurogenic locus notch homolog protein 1 OS=Mus musculus OX=10090 GN=Notch1 PE=1 SV=3) HSP 1 Score: 197.208 bits (500), Expect = 1.983e-49 Identity = 237/1013 (23.40%), Postives = 383/1013 (37.81%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS---------------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL----------------KETRKEALINIKIPKTFNEKQLII----------KKTKSPSLCDNL----CKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTS---------------------RSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQ----------KLSSSLRMVVTVFNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVN--ENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGR----------------------TPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
CS PC NG + F C C G+ G C E +N+C+ PC+NGGTCID NS +TC C F+G C+ + N CL+ C+ GT ++ F C+CR G G C VI + + C N G C + N C+C G+ G C+ C S C NGG C + SP C C G FTG C P + T + P FN I + P + + C+ N +C+ QCN AC +DGGDC DPW+ C C F+DG C+ +CN+ CLFDG DC + + + C + + + CD+ CNS +C +DG DC R+NSF L+ +++ D + + ++ E + SS L E++ ++ L ++ QCV QCF S ++ FL A G+ L++P+++ V + + +L + + A + GVLL K + ++ + S + G L D N+ +G+ +T + R PD ++R+ + ++ A L ++ T +DA DV +V+ + S G E N E ++ I+ + GA++ Q + + LH + R TPL ++++ADA + Q+L+ + +++ + TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL +F I MD P+ IA+E+ ++I L+ E
Sbjct: 1149 CSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGHTGRRCES------VINGCRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCENDART-----CGSLRCLNGGTC-ISGPRSPTCLCLGSFTGPECQFPASSPCVGSNPCYNQGTCEPTSENPFYRCLCPAKFNGLLCHILDYSFTGGAGRDIPPPQIEEACELPECQVDAGNKVCNLQCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQLTEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVPERLAAGTLVLVVLLPPDQLRNNSFHFLRELSHVLHTNVVFKRDAQGQQMIFPYYGHEEELRKHPIKRSTVGWATSSLLPGTSGGRQRRELDPMDIRGSIVYLEIDNRQCVQSSSQCFQSATDVAAFLGALASLGS-LNIPYKIEAVKSEPVEPPLPSQLHLMYV---AAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASD--GALMDDNQNEWGDEDLETKKFRFEEPVVLPDLSDQTDHRQWTQQHLD------AADLRMSAMAPTPPQGEVDADCMDV----NVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADA-QGVFQILLRNRATDLDARMH-------------------DGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANK---DMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRL---PRDIAQERMHHDIVRLLDE 2105 HSP 2 Score: 95.9005 bits (237), Expect = 2.188e-18 Identity = 81/276 (29.35%), Postives = 114/276 (41.30%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN------------IKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFAC 1111
+++ C + PCVNG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ PC C+N G C ES + F C C G+ G+ C V C P + C N N + C C GYTG C+ + C+ + C NGG C N + C+C F G C + E N P FN I + +P ++ C F G C N+F C
Sbjct: 752 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGASCQNT-------NGSYRCLCQAGYTGRNCESDID-----DCRPNPCHNGGSCTDGIN-TAFCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCPVGFNG---IHCENNTPDCTESSC---FNGGTCVDGINSFTC 1007 HSP 3 Score: 95.5153 bits (236), Expect = 2.484e-18 Identity = 71/216 (32.87%), Postives = 100/216 (46.30%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C ++PC +G + D + C C G G CE N++DC NPC + GTC+DK + + C C + G++C + C C NGGTCE G F C+C G+ C + C P I HG C N C C PG++G CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 607 CHSQPCRHGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPC-DSGTCLDKIDG-YECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAG-FTCRCPEGYHDPTCLSEVNECNSNPCI----------HGACRDGLN-GYKCDCAPGWSGTNCDINNNE-----CESNPCVNGGTCKDMTSGY-VCTCREGFSGPNCQTNINECASNPCLN 802 HSP 4 Score: 91.6633 bits (226), Expect = 3.731e-17 Identity = 72/215 (33.49%), Postives = 98/215 (45.58%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C++ PC++G C + + ++C C GW G C+ N N+C NPC NGGTC D S + C C F G CQ N C + C N GTC G ++C C + G C V C P C N G C + F C C G+ G C+ V+I C C +G C+ NGS C C+ +TG+NC + + R N
Sbjct: 720 CNSNPCIHGACRDGLN-GYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMT-SGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAG-YKCNCPLPYTGATCEVVLAPCATSP------CKNSGVCKESEDYESFSCVCPTGWQGQTCE------VDINECVKSPCRHGASCQNT-NGSYRCLCQAGYTGRNCESDIDDCRPNPCHN 918 HSP 5 Score: 88.1965 bits (217), Expect = 5.371e-16 Identity = 68/209 (32.54%), Postives = 94/209 (44.98%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF---ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
CS PC NG C D C+C G+ G+ CEENV+DC N CKNGG C+D N+ + C C ++ G C E + C+NGGTC + G + C C G+ GE C+ C + C++ + +C+C G TG C + C S+ C G C NG IC C +TG C+ + E
Sbjct: 222 CSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNT-YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGG-YNCVCVNGWTGEDCSENIDDCASAACFQGATCHDR-------VASFYCECPHGRTGLLCH------LNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDE 415 HSP 6 Score: 85.5001 bits (210), Expect = 3.186e-15 Identity = 67/206 (32.52%), Postives = 89/206 (43.20%), Query Frame = 2
Query: 332 SKLCSNRPCVNGKCVEAFDP----EFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
S C + PC N D ++ CSC G+ G C + N C+ NPC+NGGTC +++ C C + G CQ +PC + C NGG C E+ + C+C GF G C C P R H E Y C C +TG C ELP + C C NGG C+ + + C C F G+NC
Sbjct: 60 SNPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFES-SYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSY-----RCACRATHTGPHC----ELPY-VPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNC 254 HSP 7 Score: 83.1889 bits (204), Expect = 1.623e-14 Identity = 57/168 (33.93%), Postives = 77/168 (45.83%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAVQ-NIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRK 961
C NGG C + N C C+ F+G CQ NPCL+ C+N GTC +++G + C C GF G C + AC P C N G CD+ C+C PG++G C + C S+ C NGG C ++ S IC C F G C + E +
Sbjct: 31 CLNGGRC-EVANGTEACVCSGAFVGQRCQDSNPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLANP------CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADP------CASNPCANGGQCLPFES-SYICRCPPGFHGPTCRQDVNECSQ 184 HSP 8 Score: 82.4185 bits (202), Expect = 2.671e-14 Identity = 65/201 (32.34%), Postives = 95/201 (47.26%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC--IDKKNS-QFTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
C+NG E + C C + G+ C+++ N C+ PCKN GTC +D + + C+C F G LC +N CL C NGGTC+ L ++C+C G+ G+ C Q C P C N G+C + + C+C PG+ G C + E C +GG C + GS C C+ TG +C +P
Sbjct: 31 CLNGGRCEVANGTEACVCSGAFVGQRCQDS-NPCLSTPCKNAGTCHVVDHGGTVDYACSCPLGFSGPLCLTPLDNACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNP------CANGGQCLPF-ESSYICRCPPGFHGPTCRQDVN---ECSQNPGLCRHGGTCHN-EIGSYRCACRATHTGPHCELP 218 HSP 9 Score: 71.633 bits (174), Expect = 5.899e-11 Identity = 66/241 (27.39%), Postives = 93/241 (38.59%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP----------------------------------------CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C++ PC NG F+ + C C G+ G TC ++VN+C QNP C+NGGTC ++ C C F G C+ + C NC+NGG C N + C+C + G++C C ++P C N G C + C C G+TG+ C + + C S CF G C S CEC TG C +
Sbjct: 144 CASNPCANGGQCLPFESSYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVN-TYNCRCPPEWTGQYCTEDVDECQLMPNA----CQNGGTCHNT-HGGYNCVCVNGWTGEDCSENID-----DCASAACFQGATCHDR-VASFYCECPHGRTGLLCHL 372
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|Q07008|NOTC1_RAT (Neurogenic locus notch homolog protein 1 OS=Rattus norvegicus OX=10116 GN=Notch1 PE=1 SV=3) HSP 1 Score: 196.052 bits (497), Expect = 4.316e-49 Identity = 236/1013 (23.30%), Postives = 385/1013 (38.01%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS---------------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP----------------LKETRKEALINIKIPKTFNEKQLII----------KKTKSPSLCDNL----CKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTS---------------------RSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQ---KLSSSLRMVVTVFNVT-------EINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVN--ENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGR----------------------TPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
CS PC NG + F C C G+ G C E +N+C+ PC+NGGTCID N+ +TC C F+G C+ + N CL+ C+ GT ++ F C+CR G G C VI + + C N G C + N C+C G+ G C+ C S C NGG C + SP C C G FTG C P + T + P FN I + P + + C+ N +C+ QCN AC +DGGDC DPW+ C C F+DG C+ +CN+ CLFDG DC + + + C + + + CD+ CNS +C +DG DC R+NSF L+ +++ D + + + E + K S+ ++ T E++ ++ L ++ QCV QCF S ++ FL A G+ L++P+++ V + + +L + + A + GVLL K + ++ + S + G L D N+ +G+ +T + R PD ++R+ + ++ A L ++ T +DA DV +V+ + S G E N E ++ I+ + GA++ Q + + LH + R TPL ++++ADA + Q+L+ + +++ + TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL +F I MD P+ IA+E+ ++I L+ E
Sbjct: 1149 CSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGHTGRRCES------VINGCRGKPCRNGGVCAVASNTARGFICRCPAGFEGATCENDART-----CGSLRCLNGGTC-ISGPRSPTCLCLGSFTGPECQFPASSPCVGSNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFTGGAGRDIPPPQIEEACELPECQEDAGNKVCNLQCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQLTEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVPERLAAGTLVLVVLLPPDQLRNNSFHFLRELSHVLHTNVVFKRDAQGQQMIFPYYGREEELRKHPIKRSAVGWATTSLLPGTNGGRQRRELDPMDIHGSIVYLEIDNRQCVQSSSQCFQSATDVAAFLGALASLGS-LNIPYKIEAVKSETVEPPLPSQLHLMYV---AAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASD--GALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLD------AADLRVSAMAPTPPQGEVDADCMDV----NVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADA-QGVFQILLRNRATDLDARMH-------------------DGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANK---DMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRL---PRDIAQERMHHDIVRLLDE 2105 HSP 2 Score: 97.0561 bits (240), Expect = 9.980e-19 Identity = 80/276 (28.99%), Postives = 114/276 (41.30%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN------------IKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFAC 1111
+++ C + PCVNG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ PC C+N G C ES + F C C G+ G+ C + C P + C N N + C C GYTG C+ + C+ + C NGG C N + C+C F G C + E N P FN I + +P ++ C F G C N+F C
Sbjct: 752 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSPCRHGASCQNT-------NGSYRCLCQAGYTGRNCESDID-----DCRPNPCHNGGSCTDGVNAA-FCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCPTGFNG---IHCENNTPDCTESSC---FNGGTCVDGINSFTC 1007 HSP 3 Score: 91.6633 bits (226), Expect = 3.795e-17 Identity = 71/215 (33.02%), Postives = 98/215 (45.58%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C++ PC++G C + + ++C C GW G C+ N N+C NPC NGGTC D S + C C F G CQ N C + C N GTC G ++C C + G C V C P C N G C + F C C G+ G C+ ++I C C +G C+ NGS C C+ +TG+NC + + R N
Sbjct: 720 CNSNPCIHGACRDGLN-GYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKD-MTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAG-YKCNCPLPYTGATCEVVLAPCATSP------CKNSGVCKESEDYESFSCVCPTGWQGQTCE------IDINECVKSPCRHGASCQNT-NGSYRCLCQAGYTGRNCESDIDDCRPNPCHN 918 HSP 4 Score: 88.1965 bits (217), Expect = 4.653e-16 Identity = 68/209 (32.54%), Postives = 97/209 (46.41%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC--LNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
CS PC NG C D C+C G+ G+ CEENV+DC N CKNGG C+D N+ + C C ++ G C + + C + C+NGGTC + +G + C C G+ GE C+ C + C++ + +C+C G TG C + C S+ C G C NG IC C +TG C+ + E
Sbjct: 222 CSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNT-YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHN-SHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDR-------VASFYCECPHGRTGLLCH------LNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDE 415 HSP 5 Score: 85.8853 bits (211), Expect = 2.516e-15 Identity = 72/252 (28.57%), Postives = 98/252 (38.89%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKN------------------------------------SQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C PC G C + F C C G+ G CE N+N+C PC++GGTC D+ N + C C + G++C + C C NGGTCE G F C+C G+ C + C P I HG C N C C PG++G CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 570 CDPDPCHYGLCKDGVA-TFTCLCQPGYTGHHCETNINECHSQPCRHGGTCQDRDNYYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAG-FTCRCPEGYHDPTCLSEVNECNSNPCI----------HGACRDGLN-GYKCDCAPGWSGTNCDINNNE-----CESNPCVNGGTCKDMTSGY-VCTCREGFSGPNCQTNINECASNPCLN 802 HSP 6 Score: 83.1889 bits (204), Expect = 1.467e-14 Identity = 66/203 (32.51%), Postives = 87/203 (42.86%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDP----EFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PC N D ++ CSC G+ G C + N C+ NPC+NGGTC +++ C C + G CQ +PC + C NGG C E+ + C C GF G C C P R H E Y C C +TG C ELP + C C NGG C+ + + C C F G+NC
Sbjct: 63 CLSTPCKNAGTCYVVDHGGIVDYACSCPLGFSGPLCLTPLANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFES-SYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSY-----RCACRATHTGPHC----ELPY-VPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNC 254 HSP 7 Score: 80.1073 bits (196), Expect = 1.261e-13 Identity = 54/167 (32.34%), Postives = 75/167 (44.91%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRK 961
C NGG C + N C C+ F+G CQ +PCL+ C+N GTC +++G + C C GF G C P+ C N G CD+ C+C PG++G C + C S+ C NGG C ++ S IC C F G C + E +
Sbjct: 31 CLNGGRC-EVANGTEACVCSGAFVGQRCQDPSPCLSTPCKNAGTCYVVDHGGIVDYACSCPLGFSGPLCLT-----PLANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADP------CASNPCANGGQCLPFES-SYICGCPPGFHGPTCRQDVNECSQ 184 HSP 8 Score: 77.0258 bits (188), Expect = 1.083e-12 Identity = 64/201 (31.84%), Postives = 91/201 (45.27%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC--IDKKN-SQFTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
C+NG E + C C + G+ C++ + C+ PCKN GTC +D + C+C F G LC N CL C NGGTC+ L ++C+C G+ G+ C Q C P C N G+C + + C C PG+ G C + E C +GG C + GS C C+ TG +C +P
Sbjct: 31 CLNGGRCEVANGTEACVCSGAFVGQRCQD-PSPCLSTPCKNAGTCYVVDHGGIVDYACSCPLGFSGPLCLTPLANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNP------CANGGQCLPF-ESSYICGCPPGFHGPTCRQDVN---ECSQNPGLCRHGGTCHN-EIGSYRCACRATHTGPHCELP 218 HSP 9 Score: 72.0182 bits (175), Expect = 3.527e-11 Identity = 66/241 (27.39%), Postives = 93/241 (38.59%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP----------------------------------------CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C++ PC NG F+ + C C G+ G TC ++VN+C QNP C+NGGTC ++ C C F G C+ + C NC+NGG C N + C+C + G++C C ++P C N G C + C C G+TG+ C + + C S CF G C S CEC TG C +
Sbjct: 144 CASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVN-TYNCRCPPEWTGQYCTEDVDECQLMPNA----CQNGGTCH-NSHGGYNCVCVNGWTGEDCSENID-----DCASAACFQGATCHDR-VASFYCECPHGRTGLLCHL 372
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|P21783|NOTC1_XENLA (Neurogenic locus notch homolog protein 1 OS=Xenopus laevis OX=8355 GN=notch1 PE=1 SV=3) HSP 1 Score: 192.586 bits (488), Expect = 5.219e-48 Identity = 232/939 (24.71%), Postives = 389/939 (41.43%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGT--CIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGM--FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDN-LCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLT--------KCSTQTKLYELDLVLMTT---------------------------MQNFTKYKSEFLQKLSSSLRMVVTV-FNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQEL-PIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPK-TDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHP-IDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYV-------NENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLI------LEKQLRKESKQNKVRSGINGI------NLGTPCEY-FVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIK--MDPNCPCPKLIAEEKGFYEIRDLIQE 2941
NGKC++ + C C G+ GE CE +VN+C+ NPC + GT CI N + C C F G C+ + C + C NGGTC N F CKC GF G C + C + C N G C I + C C GYTG C + PV C S C+NGG C+ P C C F G C I ++ + P + I + +C+N C +N +C+ CN AC +DGGDC DPW+ C C FNDG C+ +CNN CL+DG DC K + + C + +Q+ CD+ CN+ +C +DG DC N L K ++ L EL VL T ++ T Y S+ + S+++ + + + E++ ++ L ++ QC QCF+S ++ FL A G++ +L +++ V + + K L P+ +M++ LL++F + ++ R + G+L W G+ P + +D E + K I + D +++ GD+E ++ N++ ++E Q + +L+ D + +DA + +MA + + ++ G + + G + ++ AN+I + + D G T L + ++ ++LL ++ + + V + G+ N T + TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++ LFLAA EG+ ++ K LL ++ I MD P+ IA+E+ ++I L+ E
Sbjct: 1240 NGKCIDRVG-GYNCICPPGFVGERCEGDVNECLSNPCDSRGTQNCIQLVN-DYRCECRQGFTGRRCESVVDGCKGMPCRNGGTCAVASNTERGFICKCPPGFDGATCEYDSRTCSNL------RCQNGGTC-ISVLTSSKCVCSEGYTGATC----QYPVISPCASHPCYNGGTCQFFAE-EPFFQCFCPKNFNGLFCHI----------LDYEFPGGLGKN---ITPPDNDDICENEQCSELADNKVCNANCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFNDGKCDSQCNNTGCLYDGFDCQKVEVQCNPLYDQYCKDHFQDGHCDQGCNNAECEWDGLDCANMPENLAEGTLVLVVLMPPERLKNNSVNFLRELSRVLHTNVVFKKDSKGEYKIYPYYGNEEELKKHHIKRSTDYWSDAPSAIFSTMKESILLGRHRRELDEMEVRGSIVYLEIDNRQCYKSSSQCFNSATDVAAFLGALASLGSLDTLSYKIEAVKSENMETPKPSTLYPMLSMLVIPLLIIFVFMMVIVNKKRRREHGQL---------W------------FPDGFIPKEPSKKKRRDRLGEDSVGLKPIKNMTDGSFMDDNQNEWGDEE-----TLENKRFRFE-----EQVILPELVDDKTDPRQWTRQHLDAADLRISSMAPTPPQGEIEADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDASANMISDFIGQGAQLHNQTDRTGETALHLAARYARADAAKRLLESSADANVQDNMGRTPLHAAVAADAQGVFQILIRNRATDLDARMFDGTTPLILAARLAVEGMVEELINAHADVNAVDEFGKSALHWAAAVNNVDAAAVLLKNSANK---DMQNNKEETSLFLAAREGSYETAKVLLDHYANRDITDHMD---RLPRDIAQERMHHDIVHLLDE 2112 HSP 2 Score: 102.064 bits (253), Expect = 2.491e-20 Identity = 82/271 (30.26%), Postives = 118/271 (43.54%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL------CSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVN---------------------------------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKR----ELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
+N+F C K C++ PC NG C + + + C+C G+ G CE N DC ++ C NGGTCID N+ FTC C F G+ CQ + PCLN C+NGG C N ++C+C+ G+ G +C V +++C V K++ LC N G C + T FC+C GYTG C+++ + C + C NG C G CEC + G NC+ + E
Sbjct: 925 INMFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVN-SYTCTCQPGFSGIHCESNTPDCTESSCFNGGTCIDGINT-FTCQCPPGFTGSYCQHDINECDSKPCLNGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNN-FYRCECKSGWTGVYCDVPSVSCEVAAKQQGVDIVHLCRNSGMC-VDTGNTHFCRCQAGYTGSYCEEQVDE-----CSPNPCQNGATCTDYLGGYS-CECVAGYHGVNCSEEINE 1185 HSP 3 Score: 102.064 bits (253), Expect = 3.129e-20 Identity = 88/264 (33.33%), Postives = 118/264 (44.70%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCD---NLCKAS--FENGICDQQCNTFAC 1111
C + PC N C++ EF+C C G++G CE N+++C NPC + G CIDK N +F C+C + F GNLCQ + + C + C+NG C N + C+C GF G C C IP +G C T C C PGYTG CD C S C NGG C +NG IC C TG NC + + N K + + + + LC+ N C ++ G C Q N F C
Sbjct: 455 CLSNPCQNDSTCLDQIG-EFQCICMPGYEGLYCETNIDECASNPCLHNGKCIDKIN-EFRCDCPTGFSGNLCQHDFDECTSTPCKNGAKCLDGPNS-YTCQCTEGFTGRHCEQDINEC--IPDPCH-----YGTCKDGI-ATFTCLCRPGYTGRLCDNDINE-----CLSKPCLNGGQCTDRENGY-ICTCPKGTTGVNCETKIDDCASNLCDNGKCIDKIDGYECTCEPGYTGKLCNININECDSNPCRNGGTCKDQINGFTC 701 HSP 4 Score: 100.908 bits (250), Expect = 5.845e-20 Identity = 72/199 (36.18%), Postives = 94/199 (47.24%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C NRPC NG + + ++C+C G+ G CE +++DC NPC NGG+C D N F CNC + F G C+ + N C + C+NG C N + C C+ GF G C P C N G C I T C+C PG+TG C C S C NGG C+ G+ C C +TG NC
Sbjct: 872 CVNRPCRNGATCQNTNGSYKCNCKPGYTGRNCEMDIDDCQPNPCHNGGSCSDGIN-MFFCNCPAGFRGPKCEEDINECASNPCKNGANCTDCVNS-YTCTCQPGFSGIHCESN------TPDCTESSCFNGGTC-IDGINTFTCQCPPGFTGSYCQHDINE-----CDSKPCLNGGTCQD-SYGTYKCTCPQGYTGLNC 1055 HSP 5 Score: 98.2117 bits (243), Expect = 3.974e-19 Identity = 69/211 (32.70%), Postives = 100/211 (47.39%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
+++ C + PC+NG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G +C+ PC C+NGG C ES + F C+C G+ G+ C + C P + C N N + C C PGYTG C E+ ++ C+ + C NGG C N C C F G C + E
Sbjct: 751 INNNECESNPCMNGGTCKDMTGAYICTCKAGFSGPNCQTNINECSSNPCLNHGTCIDDV-AGYKCNCMLPYTGAICEAVLAPCAGSPCKNGGRCKESEDFETFSCECPPGWQGQTCEIDMNECVNRPCRNGATCQNT-------NGSYKCNCKPGYTGRNC----EMDID-DCQPNPCHNGGSCSDGINMF-FCNCPAGFRGPKCEEDINE 947 HSP 6 Score: 97.8265 bits (242), Expect = 5.076e-19 Identity = 71/210 (33.81%), Postives = 103/210 (49.05%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLC-QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEA 967
C++ PC NG F+ ++ C C G+ G TC++++N+C QNPCKNGG CI++ S + C C ++F G C + PC C NGGTC ++ + C C GF G+ C CP C N G C N T C+C P +TG C + + E + C NGG C G C C +TG++C+ + + A
Sbjct: 145 CASNPCANGGKCLPFEIQYICKCPPGFHGATCKQDINECSQNPCKNGGQCINEFGS-YRCTCQNRFTGRNCDEPYVPCNPSPCLNGGTCRQTDDTSYDCTCLPGFSGQNCEENIDDCP------SNNCRNGGTCVDGVN-TYNCQCPPDWTGQYCTEDVD---ECQLMPNACQNGGTCHNTYGGY-NCVCVNGWTGEDCSENIDDCANAA 342 HSP 7 Score: 87.0409 bits (214), Expect = 9.856e-16 Identity = 78/243 (32.10%), Postives = 105/243 (43.21%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLN------VN--------------------------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI-CECKGEFTGKNCTIPLKE 952
C++ C NGKC++ D + C+C G+ G+ C N+N+C NPC+NGGTC D+ N FTC C + ++C E NPC++ VN C NGGTC+ + G + C C+ GF G C C P C NHG C I C C YTG C+ V C C NGG CK ++ CEC + G+ C I + E
Sbjct: 644 CASNLCDNGKCIDKID-GYECTCEPGYTGKLCNININECDSNPCRNGGTCKDQING-FTCVCPDGYHDHMCLSEVNECNSNPCIHGACHDGVNGYKCDCEAGWSGSNCDINNNECESNPCMNGGTCKDM-TGAYICTCKAGFSGPNCQTNINECSSNP------CLNHGTC-IDDVAGYKCNCMLPYTGAICEA-----VLAPCAGSPCKNGGRCKESEDFETFSCECPPGWQGQTCEIDMNE 871 HSP 8 Score: 85.5001 bits (210), Expect = 2.902e-15 Identity = 63/183 (34.43%), Postives = 86/183 (46.99%), Query Frame = 2
Query: 392 EFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTC-IDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
+F C C G+ + C V N C+ NPC+NGGTC + +++ C C + G+ CQ +PC + C NGG C E + CKC GF G C C P C N G+C I + C C +TG CD+ + C C NGG C+ D+ S C C F+G+NC
Sbjct: 84 DFICHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLNSVTEYKCRCPPGWTGDSCQQADPCASNPCANGGKCLPFEI-QYICKCPPGFHGATCKQDINECSQNP------CKNGGQC-INEFGSYRCTCQNRFTGRNCDEPY-----VPCNPSPCLNGGTCRQTDDTSYDCTCLPGFSGQNC 253 HSP 9 Score: 74.3294 bits (181), Expect = 6.866e-12 Identity = 73/239 (30.54%), Postives = 108/239 (45.19%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL-CSNRP--CVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC---IDKKNSQFTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+ + +L C L +++ L C+ C+NG +C C C + + GE C+ I+N C N GTC + F C+C F +C +N C+N C NGGTCE L + ++C+C G+ G+ C Q C P C N G+C + + CKC PG+ G C + C + C NGG C + + GS C C+ FTG+NC P +N
Sbjct: 4 IGLAVLLCSLPVLTQGLRCTQTAEMCLNGGRCEMTPGGTGVCLCGNLYFGERCQFPNPCTIKNQCMNFGTCEPVLQGNAIDFICHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLNSVTEYKCRCPPGWTGDSCQ-QADPCASNP------CANGGKCLPF-EIQYICKCPPGFHGATCKQDINE-----CSQNPCKNGGQC-INEFGSYRCTCQNRFTGRNCDEPYVPCNPSPCLN 228
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Match: sp|P46531|NOTC1_HUMAN (Neurogenic locus notch homolog protein 1 OS=Homo sapiens OX=9606 GN=NOTCH1 PE=1 SV=4) HSP 1 Score: 191.045 bits (484), Expect = 1.566e-47 Identity = 236/973 (24.25%), Postives = 378/973 (38.85%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP----------CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL----------------KETRKEALINIKIPKTFNEKQLII---------KKTKSPSLCDNLC-----KASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLT---------KCSTQTKLYELDLVLMTTM----------QNFTKYKSE--------------------FLQKLSSSLRMVVTVFNVTEINFNF--ATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVN--ENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGI------NLGTPCEYFVKK-TTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C + PC NG ++CSC G +G CE NV+DC NP C N GTC+D+ ++C C F+G C+ + N CL+ C+ GT ++ F C+CR G G C VI K + C N G C + N CKC G+ G C+ C S C NGG C + SP C C G FTG C P + T + P FN I + P L + C + N +C QCN AC +DGGDC DPW+ C C F+DG C+ +CN+ CLFDG DC ++ + + C + + + CD+ CNS +C +DG DC + + + S+ L EL VL T + F Y E L ++ +SL + + ++ L ++ QCV QCF S ++ FL A G+ L++P+++ V + + +L + A + GVLL K + ++ + S + G L D N+ +G+ +T + R PD ++R+ + ++ A L ++ T +DA DV +V+ + S G E N E ++ I+ + GA++ Q + + LH + R+ A + + ++ ++ + + V + G+ N T + + TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N +++PLFLAA EG+ ++ K LL +F I MD P+ IA+E+ ++I L+ E
Sbjct: 1187 CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDC--NPPVDPVSRSPKCFNNGTCVDQVGG-YSCTCPPGFVGERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCES------VINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDART-----CGSLRCLNGGTC-ISGPRSPTCLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNC--TQSLQCWKYFSDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYYGREEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMDVRGSIVYLEIDNRQCVQASSQCFQSATDVAAFLGALASLGS-LNIPYKIEAVQSETVEPPPPAQLHFMYV---AAAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASD--GALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLD------AADLRMSAMAPTPPQGEVDADCMDV----NVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADAN-----IQDNMGRTPLHAAVSADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANK---DMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRL---PRDIAQERMHHDIVRLLDE 2115 HSP 2 Score: 100.523 bits (249), Expect = 8.938e-20 Identity = 72/213 (33.80%), Postives = 102/213 (47.89%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
CS++PC +G + D + C C G G CE N++DC +PC + GTC+DK + + C C + G++C + C C NGGTCE NG F C+C G+ C + C P HG C N C CDPG++G CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 607 CSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDS-GTCLDKIDG-YECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGING-FTCRCPEGYHDPTCLSEVNECNSNPCV-------HGACRDSLN-GYKCDCDPGWSGTNCDINNNE-----CESNPCVNGGTCKDMTSGY-VCTCREGFSGPNCQTNINECASNPCLN 802 HSP 3 Score: 95.5153 bits (236), Expect = 2.897e-18 Identity = 69/220 (31.36%), Postives = 98/220 (44.55%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+++ C + PCVNG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ PC C NGG C E+ F C C G+ G+ C V C + P + C N HG C C GY+G C+ + C+ + C NGG C N + C+C F G C + E + N
Sbjct: 752 INNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHG--------GYRCHCQAGYSGRNCETDID-----DCRPNPCHNGGSCTDGIN-TAFCDCLPGFRGTFCEEDINECASDPCRN 956 HSP 4 Score: 89.7373 bits (221), Expect = 1.454e-16 Identity = 71/215 (33.02%), Postives = 98/215 (45.58%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C++ PCV+G C ++ + ++C C GW G C+ N N+C NPC NGGTC D S + C C F G CQ N C + C N GTC G ++C C + G C V C P C N GEC + F C C G+ G C+ V+I C C +G C+ G C C+ ++G+NC + + R N
Sbjct: 720 CNSNPCVHGACRDSLN-GYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKD-MTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAG-YKCNCLLPYTGATCEVVLAPCAPSP------CRNGGECRQSEDYESFSCVCPTGWQGQTCE------VDINECVLSPCRHGASCQNTHGGY-RCHCQAGYSGRNCETDIDDCRPNPCHN 918 HSP 5 Score: 86.6557 bits (213), Expect = 1.240e-15 Identity = 68/201 (33.83%), Postives = 95/201 (47.26%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC--IDKKN-SQFTCNCTSQFIGNLC--QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
C+NG EA + C C + G C++ N C+ PCKN GTC +D++ + + C+C F G LC +N CL C NGGTC+ L ++C+C G+ G+ C Q C P C N G+C + + C C P + G C + E G K C +GG C + GS C C+ TG NC P
Sbjct: 31 CLNGGKCEAANGTEACVCGGAFVGPRCQD-PNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNP------CANGGQCLPF-EASYICHCPPSFHGPTCRQDVN---ECGQKPGLCRHGGTCHN-EVGSYRCVCRATHTGPNCERP 218 HSP 6 Score: 85.8853 bits (211), Expect = 2.277e-15 Identity = 67/209 (32.06%), Postives = 95/209 (45.45%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC--LNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
CS PC NG C D C+C G+ G+ CEEN++DC N CKNGG C+D N+ + C C ++ G C + + C + C+NGGTC + G + C C G+ GE C+ C C++ + +C+C G TG C + C S+ C G C NG IC C +TG C+ + E
Sbjct: 222 CSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNT-YNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGG-YNCVCVNGWTGEDCSENIDDCASAACFHGATCHDR-------VASFYCECPHGRTGLLCH------LNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDE 415 HSP 7 Score: 81.2629 bits (199), Expect = 5.387e-14 Identity = 68/211 (32.23%), Postives = 93/211 (44.08%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLK 949
C++ PC +G C++ D + C+C G+ G C N+++C NPC NGGTC D N FTC C + C E NPC++ G C NG ++C C G+ G C + N C P C N G C +MT C C G++G C C S+ C N G C + D C C +TG C + L
Sbjct: 645 CASSPCDSGTCLDKID-GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGING-FTCRCPEGYHDPTCLSEVNECNSNPCVH------GACRDSLNG-YKCDCDPGWSGTNCDINNNECESNP------CVNGGTCK---DMTSGYVCTCREGFSGPNCQTNINE-----CASNPCLNQGTC-IDDVAGYKCNCLLPYTGATCEVVLA 831 HSP 8 Score: 81.2629 bits (199), Expect = 5.714e-14 Identity = 63/203 (31.03%), Postives = 88/203 (43.35%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFD----PEFRCSCWHGWKGETCEENV-NDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PC N D ++ CSC G+ G C + N C+ NPC+NGGTC +++ C C + G CQ +PC + C NGG C E + C C F G C C +K LC + G C + C C +TG C++ + C C NGG C+ + + C C FTG+NC
Sbjct: 63 CLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFE-ASYICHCPPSFHGPTCRQDVNEC----GQKPGLCRHGGTCHNEVG-SYRCVCRATHTGPNCERPY-----VPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNC 254 HSP 9 Score: 79.337 bits (194), Expect = 2.077e-13 Identity = 56/165 (33.94%), Postives = 72/165 (43.64%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLEN---GMFQCKCRYGFIGEFCAVQ-NIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C NGG C + N C C F+G CQ NPCL+ C+N GTC ++ + C C GF G C + AC P C N G CD+ C+C PG++G C + C S+ C NGG C + S IC C F G C + E
Sbjct: 31 CLNGGKC-EAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNP------CRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADP------CASNPCANGGQCLPFE-ASYICHCPPSFHGPTCRQDVNE 181 HSP 10 Score: 66.2402 bits (160), Expect = 2.198e-9 Identity = 56/183 (30.60%), Postives = 77/183 (42.08%), Query Frame = 2
Query: 395 FRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
+RC C G CE C +PC+NGGTC + C C F G C+ + C NC+NGG C N + C+C + G++C C ++P C N G C + C C G+TG+ C + + C S CF+G C S CEC TG C +
Sbjct: 202 YRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVN-TYNCRCPPEWTGQYCTEDVDECQLMPNA----CQNGGTCHNT-HGGYNCVCVNGWTGEDCSENID-----DCASAACFHGATCHDR-VASFYCECPHGRTGLLCHL 372
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A158QVN9 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS8230 PE=4 SV=1) HSP 1 Score: 265.003 bits (676), Expect = 1.460e-68 Identity = 262/1051 (24.93%), Postives = 434/1051 (41.29%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEA-------FDPE----FRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNM----------------TLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKA------SFENGICDQQCNTFAC--NYDGGDCDPWRKC-------YGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDC-------------------------HKSSCKFH-KCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVV--TVFNVTE----INFNFATALLIKLHVNYTQCVLYG--GQCFSSLEQISNFLKAGIEKGNV-LSLPFRLARVDTRIISASKKQELPIYT-----MXXXXXXXXXXXXXXXXG---------VLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQL--KDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRK----------------YETIN-RNH-QALAFQLISDSLEST----DGIHPIDAGL---------GDVYTMASVK-----NHMKYD-----------EKYQTSSLEGLGEYVNE--------------NGESLMHIAARMNSGANIIKQI------------NAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQL----RKESKQNKVRSGINGINLGTPC-------------EYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C +PC NG C E ++P+ + C C GW+G C NV+DC NPC+NGG C DK N+QF C+C FIG C++ +PCL+ C+N G C+S G++QC C + G+ C I C + C N G C++ + C C+PG+TG CD++ ++ C C NG C + N C+C F G C P++ + IP N KK ++ + D C+ + NG C +C C C W C +G + C + DGVC+ EC C +DG DC ++SSC C+ +Y + +C ECN P CGFDGGDC T S + + LVL T + + L +++ +LR VV V T+ ++ + + I L ++ G+ + S++ ++ LKA ++ +V L LP V S + P+ + + L+ + L G V+ R W + R +++T G+W+P S + S+ G P+ P + D Q +K + + + + H G + +P + + + + ++TI+ R H Q A ++ L ST DG+HP+ + +++AS + +H+K + T + G+G ++ NGE+++H+AARMN GA I+++ ++ L LD+ GR+PL +S A D E+T L LE++ R + V G +++T L+ ++K E+ LLLDEG + +D GR++VHW+A+ N + LL R+SH K F ++ + +D+ D++PL LA E ++++ + LL + + D P A+ +GF + L+ E
Sbjct: 58 CDAQPCKNGASCRERDVPQSIYYEPQNRLPYECDCQFGWEGVNCTINVDDCKGNPCQNGGRCEDKPNAQFVCHCRDGFIGQKCEYRDPCLDSPCQNNGRCDSSPLGVYQCICPRWYEGQNCEKAKIPC----ESTHNQCRN-GTCEVLYELFETRVQSQPKTASRISGFRCNCNPGWTGVFCDRELDV-----CLHHECQNGAKCVGVGNHY-QCQCPEGFDGLLCEQPIRAS---------IPNQSN------KKREAQNGLDEKCQVLGCANLTATNGTCLGRCIQAGCFNQEQLNACRAWIDCLEATKSDFGPGQRSCVERYRDGVCDHECAISSCFYDGFDCTDAGNQNWSSPNMDINRRMSTFTPPNRSSCPTEDHCTAVYGDGVCHPECNFPTCGFDGGDCLTPLDPSTPPR------IDNVRTGYIALVLNTDRNTYITLEKTVLSRVAEALRAVVRPAVDEKTQQPVIVDMDGGLRIRITLTIDLLPEGFQANAGEAYESIDLAAHTLKAALDTKSVDLPLPVAQLWVAKDPHSPPPGETTPVTPGGLPFLRSKDAIGLYIVLCVLSGAVIILLVFIVIQRRPWKQARKRVRTHGIWSPPSFFFHSSG----GGGSAHPRAPPVLSTDPGILLQQGHKTVPKTAASQLEDLLHPGGKRPRYSPPTTESYEEEACGLLHQESHTGGYTTHQTIDPRPHRQTDAATAVTKELTSTIRGSDGLHPLSPEALSKLEVVIRDNQHSLASPQLYVHPHHLKRSFSTVEASEFESPVFVTGAGRGIGAATDKLQHQDSFVTTRNPLNGETILHLAARMNVGARAIRRLCGTLVAEDGAPASSEKTLALLCLDKDGRSPLTASAATDGLETTTALYRLEREAITCSRSAASAQSVPPTSTSEGGGATSNEKPSTEARRRARHVESRRSTPLMVSLKAGCTEVTKLLLDEGCSIQGVDETGRNLVHWAAVLNAASLLTRISHTKGFSRMLEARDDCDRTPLLLAVRENSLEAAQILLEHQAIIDV-FDYTDSSPISEAKARGFTRMLALLME 1071
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: V4BGJ2 (Uncharacterized protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_184955 PE=4 SV=1) HSP 1 Score: 228.024 bits (580), Expect = 1.272e-56 Identity = 262/997 (26.28%), Postives = 413/997 (41.42%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDK---------------------------------------KNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC--KVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNL-CKASFENGICDQQCNTFACNYDGGDCD----PWRKCYG-NDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHKCSELYQ--------NKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTM--QNFTKYKSEFLQKLSSSLRMVVTVF------------------NVTE-INFNFATALLIKLHVNYTQCVLYG-GQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGD---QEPDNPISINNRKRKYETINRNHQALAFQLISDSLEST--------------------DGIHPIDA------GLGDV--YTMASVK-NHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLH----------------------SLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLI 2935
C+N+PC N G C + D +F+CSC G G CE N NDC N C +GGTC+DK ++ + C C + F G LC+ C C+NGGTC + ++G +C C G+ G++C Q+ C P C N G C + FC C G +G C E+ C S C N G C K+ G C C +TG +C + A+ I P T + L + K LC+ C+A NG CD +CN AC+YD +C PW++C G D C VF DG CNP+CNN +CL+DG DC K +C+ +Y N CD+ C++ +C +DG DC S +L E LV++ + + F EFL+KL LR VV V +V++ I + L ++ C Y +CF + + + F+ A +++ N L + ++++ + + P T + + + ITL+ +++ + K + A W P ++ S N P ++KD +K G + D+ HGD E ++P + R+R E + + Q+L I DS + T G PID G G + +AS++ N + ++ S EG E+ + I + GA+I Q + + LH +LD GRTPL +++AADA + Q+L+ + +K TT LI A +L ++M+ L++ + +N D+ G++ +HWSA NN E L + D +DN+D++PLFLAA EG+ ++ K LL ++ I C P+ +A+E+ ++I L+
Sbjct: 905 CANQPCANNGVCHDLVD-DFKCSCPAGTLGLLCEINSNDCFDNACYHGGTCVDKIGHYECKCPPGFAGPRCEGDVNECSSNPCSALGTQDCVQLDNDYRCQCKAGFSGRLCENRIQCSEAPCKNGGTCTNTDSGP-KCSCLKGYSGDYCEFQSADCDSSP------CQNDGTCRPTQD-GYFCLCPAGASGINC----EIDEMDECLSSPCKNDGTCHDKI---GYYECYCPRYYTGIHC----QNYDVNAVPGIGRPVTM-KPSLNLNPDKE--LCEQYGCEAKANNGKCDNECNMHACDYDNKECSYGMKPWKECSGMRDGVFCWKVFKDGTCNPQCNNEECLYDGFDCQT---KLKECNPIYDSYCKKYYGNGHCDQGCDTEECEWDGLDCDKSPE----------------RLAEGTLVIIVLVEPEAFRNMSKEFLRKLGHLLRAVVRVLKDKNGSPMIYPWQQKEGDDVSDVIRVKRWAETKVYLEIDNRGCYKYSTDECFDNTDNAAQFVAAALQR-NDADLGMPVGKIES--LGKEPTVDSPAITFVYIVVACGAILLITLVVIIV------ISRKRERAVTWFPEGFFNKRGSEKAGVRNRRGPDGEEMKDVQK----------GSHHSQLDKMDDRHGDWGEDEEEHPKA--KRQRIDEQGDSSDQSLVNFEIQDSRQWTQKHMEAANVTNPSILTLTPPQGDDPIDTKDINARGPGGMTPLMLASLRGNTLDTSCDDESGSAEG----NEEDNRAADVINNLLFQGASINLQTDRTGETSLHLAARYARADAAKVLLDAGADCNALDSTGRTPLHTAVAADA-QGVFQILLRNRSTNLNAK-------------------MYDGTTPLILAARLAIEDMVEDLINADADINAFDNNGKTALHWSAAVNNVEATESLLERNANR---DAQDNKDETPLFLAAREGSFEAAKALLNHYANREITDHLECL-PREVADERHHHDIVQLL 1810 HSP 2 Score: 101.293 bits (251), Expect = 1.355e-17 Identity = 73/211 (34.60%), Postives = 101/211 (47.87%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCK------SDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C++ PC++G + + C+C G+ G CE N NDC ++ C N G CID N+ FTC C F G++CQ NPC C N GTC + NG + C C YGF G C C K C N G C+ + N C C +TG++CD ++ +P S C NGG+CK L + C C+ + G C + E
Sbjct: 666 CASNPCMHGSTCTDYVNSYTCTCRLGFSGVHCEVNDNDCTKSSCLNDGKCIDGVNN-FTCQCKGGFTGSICQTRINPCDTNPCMNAGTCFN-HNGNYYCNCPYGFQGTHCERVQDWC------KNNPCQNSGTCEQFAN-NFRCTCTSDWTGEKCDIRR-VPCNSAAALKGVDVSKLCRNGGICKNLGGTTHECICQAGYEGSYCEREINE 866 HSP 3 Score: 94.3597 bits (233), Expect = 1.695e-15 Identity = 108/360 (30.00%), Postives = 147/360 (40.83%), Query Frame = 2
Query: 317 LVIVSSKLCSNRP--CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICD---QQCNTFACNYDGGDCDPWRKCYGNDLK------HCKGVFNDGVCNPECNNVDC----LFDGEDCHKSSCKFHKCSELYQNKICDEECNSPQCGFDG 1345
L + C P C NG + F C C +GW G C EN++DC NPC NGG C D+ F C C G C ++ C + C G +CE+ +G C C+ G+ G+ C+ C + C + G C P + C C G+TG C+ V I C S+ C N G C + + G+ C C FTG+NC + E IN + Q ++ K K C A FE C +C TF C +GG C+ Y K HC+ ++ C VDC DG D + SC L Q I +EC+S C F G
Sbjct: 5 LCQIDVDECETTPFICQNGGTCMNHNDGFMCICVNGWTGSDCSENIDDCKNNPCFNGGNCEDRV-GYFYCKCPRGKTGMRCHLDDACESNPCNAGASCETSPIDGSPICTCKRGWTGDTCSRDVDEC---TESADTPCEHGGTCINTPG-SYKCDCAVGFTGPWCE------VNINECSSNPCINDGTC-LDEKGAYRCLCMPGFTGRNCEVEYDECGSNPCINGGV------CQDLVNKFKC------TCPAGFEGPTCAVNIDECETFPC-LNGGTCNDQINTYTCTCKTGYSGVHCQENVDN------CRKVDCGHGTCVDGLDTYTCSCLPGYTGLLCQYDI--DECSSNPCKFGG 331 HSP 4 Score: 93.5893 bits (231), Expect = 3.306e-15 Identity = 77/231 (33.33%), Postives = 102/231 (44.16%), Query Frame = 2
Query: 314 LLVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNE 1003
LL CS+ PC G D + C C +G G+ CE+N N+C+ NPC NG TCID N ++ C C + G C+ + + C + C NGG C L N F+C+C G+ C C P C N+G C N C C GY G RC C S+ C +GG C N S C+CK F GKNC + E ++ + NE
Sbjct: 313 LLCQYDIDECSSNPCKFGGTCSNLDNSYECRCPYGTSGQNCEKNYNECVSNPCHNGATCIDGIN-RYNCKCKPGYEGTHCELDIDDCASQPCHNGGKCTDLIN-KFKCECPAGYYDAECRSNVNECGSNP------CMNYGTCVDGVNK-FECLCLDGYGGHRCQNDIN-----DCVSNPCQHGGTCNDHLN-SYSCDCKPGFEGKNCDKNINECASNPCVHGECVDLANE 528 HSP 5 Score: 89.7373 bits (221), Expect = 4.699e-14 Identity = 108/387 (27.91%), Postives = 160/387 (41.34%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINI-KIPKTFNEKQLIIKKTKSPSLCDNLCKASFEN-----GICDQQCNTFACN----YDGGDCDP-WRKCYGNDLKH--CKGVFND--GVCNPECNNVDCLFDGEDCHKSSCKFHKCSELYQNKICDEECNSPQCGFDG 1345
C + PC+NG + +F+C+C G++G TC N+++C PC NGGTC D+ N+ +TC+C + G LCQ++ + C + C+ GGTC +L+N ++C+C YG G+ C C P C+N C I CKC PGY G C EL ++ C S C NGG C L N CEC + C + E +N N+ + + C N N G C+ N+++C+ ++G +CD +C N H C + N+ CNP + +C + CH S C+ H + N D EC P GF G
Sbjct: 209 CGSNPCINGGVCQDLVNKFKCTCPAGFEGPTCAVNIDECETFPCLNGGTCNDQINTYTCTCKTGYSGVHCQENVDNCRKVDCGHGTCVDGLDTYTCSCLPGYTGLLCQYDIDECSSNPCKFGGTCSNLDN-SYECRCPYGTSGQNCEKNYNECVSNP------CHNGATC-IDGINRYNCKCKPGYEGTHC----ELDID-DCASQPCHNGGKCTDLINKFK-CECPAGYYDAECRSNVNECGSNPCMNYGTCVDGVNKFECLCLDGYGGHRCQNDINDCVSNPCQHGGTCNDHLNSYSCDCKPGFEGKNCDKNINECASNPCVHGECVDLANEYHCNCNPPYSGKNCEQELNPCHPSPCQNHA-QCVPTNNYKDFECRCPT-GFTG 579 HSP 6 Score: 88.9669 bits (219), Expect = 6.932e-14 Identity = 70/199 (35.18%), Postives = 95/199 (47.74%), Query Frame = 2
Query: 344 SNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
S PC NG + F+C C G++G+ CE N +DC NPC NGGTC+D+ ++C C F G CQ + + C + C +G TC N + C CR GF G C V + C + C N G+C D N T C+C G+TG C + C ++ C N G C NG+ C C F G +C
Sbjct: 591 SGSPCRNGAQCVNKNGSFKCICLRGYEGKRCEVNHDDCAPNPCINGGTCVDEIGG-YSCRCVDGFGGQHCQNDIDECASNPCMHGSTCTDYVN-SYTCTCRLGFSGVHCEVNDNDC------TKSSCLNDGKCIDGVNNFT--CQCKGGFTGSICQTRINP-----CDTNPCMNAGTC-FNHNGNYYCNCPYGFQGTHC 773 HSP 7 Score: 85.1149 bits (209), Expect = 1.227e-12 Identity = 65/200 (32.50%), Postives = 95/200 (47.50%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECD-IYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C++ PC NG + + C C G++G+ CE N++DC PC N G C D + F C+C + +G LC+ N C + C +GGTC + G ++CKC GF G C C P C+ G D + + C+C G++G C+ + I C C NGG C D+G P C C ++G C
Sbjct: 867 CASAPCKNGATCKDLVNHYTCQCMTGFQGQNCEYNIDDCANQPCANNGVCHDLVD-DFKCSCPAGTLGLLCEINSNDCFDNACYHGGTCVD-KIGHYECKCPPGFAGPRCEGDVNECSSNP------CSALGTQDCVQLDNDYRCQCKAGFSGRLCENR------IQCSEAPCKNGGTCTNTDSG-PKCSCLKGYSGDYC 1051
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A3B3BFS6 (Notch receptor 2 OS=Oryzias melastigma OX=30732 PE=4 SV=1) HSP 1 Score: 227.254 bits (578), Expect = 2.949e-56 Identity = 242/954 (25.37%), Postives = 409/954 (42.87%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP------CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTG------KNCTIP-------LKETRKEALINIKIPKTFNEKQLIIKKTKSPSLC-DNLCKASFENGICDQQCNTFACNYDGGDCD-----PWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHK---SSCKFHK-CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLV-LMTTMQNFTKYKSEFLQKLSSSLRMVVTVFNVTEINFNFATA-------------LLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDN----------PISINN--RKRKYETINRNHQALAFQLISDSLESTDGIHPIDAGLGDVYT---MASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLH----------------------SLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C +RPC+NG +C+ + F CSC G G CE N +DC P C NGG C+D ++TC+C F+G C+ + N C + C GT + +E ++C CR G+ G C C P C N G C + + C C PGYTG C + + C C NGG C + NG P+C+C F+G + C++ +K+ + + P F+ + + SP C D C+ + +CD QCN C +DGGDC PW C + C +F +G C+ ECNN CLFD +C + S C++ K C + Y N ICD C CG+DG DC + + + + Q K DL + ++ + + +++ ++ MV + V + + A A L+ L ++ +C CFS E++++F+ A K + LP+ L V + +I ++ P Y M L + + + ++L ++ K K +W P ++ G +K+FK Q + G+SQ H D+ P P++++ +R++ +R ++ D L++ G ++ D +T +AS++N D E G+ E G S+ I+ + GA+++ Q + + LH + D GRTPL +++AADA + Q+LI + +++ N TT LI A +L + M+ L+ + +N +D G+S +HW+A NN +E + D++DN++++PLFLAA EG+ ++ + LL +++ I MD P+ A+E+ ++I L+ +
Sbjct: 1197 CHSRPCLNGGRCINLIN-RFTCSCPPGTHGVQCEVNEDDCAPQPGSSEPRCLNGGQCVDGV-GRYTCSCPPGFVGEHCEGDVNECRSAPCHGPGTLDCVELVNDYRCLCRLGYTGRHCESMVNLCVSKP------CRNGGVCSMNSSSVRGYTCSCPPGYTGSTCAELQNH----SCGGLRCLNGGSC-LHHNGQPLCQCPPGFSGPLCENEQRCSVTCHNGGTCVKDPANPFQHSCRCPPLFSGHFCEKRASLSPPTCPDPQCEHLSGDKVCDNQCNNHQCQWDGGDCSLSCLQPWVNCTAS--VPCWDLFQNGRCDQECNNAACLFDSFECQQAPPSVCEYDKYCKDHYGNGICDHSCYDEACGWDGLDCSDNITPELATGTLIIVVRLQPKELLDDLRGFLRSLGGLLRTNVQ-VKRNDNNQPMVFPYYGVIDKHGQQAQASRRRREVEKEVIGSLVHLDIDNRECSRTSSHCFSHAEKVASFIAAAHIKKS--ELPYPLVSVTSEVI----EEPEPTYLMYLVGVGVAVVL------LILVLGMLAVKRKHKHGALWLPEGFIVSNDKRREP---VGQDDF-DMKNFK--LQDGGLMDGGQSQ-------RWHEDEAPPKKSRTEDKPLLPLALDGGVDQREWTLQHRKAADISHTPPQDDLDA--GCLDVNVKGPDGFTPLMVASLRNGGGLDCSVHAEEEEESGD---EPGPSI--ISDLIAQGASLMAQTDRTGETALHLAARYARADAAKRLLDAGADPNAHDNMGRTPLHAAVAADA-QGVFQILIRNRATELDARMN-------------------DGTTPLILAARLAVEGMVEELIHCHADINAVDDHGKSALHWAAAVNN---VEATLVLLKNGANRDMQDNKEETPLFLAAREGSFEAAQVLLDHYSNRDITDHMDRL---PRDTAQERMHHDIVRLLDQ 2076 HSP 2 Score: 111.309 bits (277), Expect = 1.238e-20 Identity = 74/222 (33.33%), Postives = 112/222 (50.45%), Query Frame = 2
Query: 317 LVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
L + + C+ +PCV+G CVE +RC C GW G CE+ ++C NPC+NGG C+D+ N +TC C F GN C+ + C + C N G C N + C+C + G+ C V+ C P C + G C + T F C+C G+ G RC + + C SD C N G+C+ GS IC+C+ ++G+NC + + + +N
Sbjct: 722 LCLSGTDHCARQPCVHGDCVEQ-QLGYRCECEAGWVGAHCEQEKDECQPNPCQNGGNCLDRHNG-YTCQCQPGFTGNNCEKNRDECASSPCLNRGVCIDGVN-SYTCRCSPPYTGKHCEVEQAPCASHP------CKSGGVCLPSADYTSFTCRCPTGWQGARCSEDVDE-----CLSDPCRNDGLCENR-RGSYICKCQRGYSGQNCQTDIDDCKPNPCLN 928 HSP 3 Score: 103.99 bits (258), Expect = 2.293e-18 Identity = 81/255 (31.76%), Postives = 113/255 (44.31%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE---------------------------------------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C++ PC NG + F C+C G++G CE N+ +C ++ C N GTC+D NS F+C C F+G C++E N C V+C NGGTC S + C+C+ G+ G +C V N++C +K +C N G+C N + C C PGYTG C E PV+ C S+ C NG CK G+ C CK F G NC + E +N
Sbjct: 959 CASNPCRNGATCHDYVNSFVCACREGFRGIQCEHNIPECTESSCLNNGTCVDGINS-FSCRCPLGFLGLFCEYESNECDSQPCKNGGSCTDGLRTYSCVCPVGYSGSNCQNYVNVCKGVHCLNGGTC-SQSTTSWVCRCQAGWTGLYCDVPNMSCQNFAARKGVDVENVCKNAGQCKNVGN-SHQCICQPGYTGSYC----EDPVDE-CLSNPCRNGATCKDY-QGNYQCTCKPGFQGVNCEYDVDECHSRPCLN 1204 HSP 4 Score: 95.5153 bits (236), Expect = 8.322e-16 Identity = 68/209 (32.54%), Postives = 95/209 (45.45%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDN-GSPICECKGEFTGKNCTIPLKETRKEALIN 976
C NG + C C +GW G C EN+NDC++ C+ G TCID+ S F C C G LC + C++ C +G C++ G F C C G++G C + C + C + G+C + + + C C GYTG RC++ C S C N G C LD G C C FTG +C I + E +N
Sbjct: 316 CQNGGTCHNGIGSYNCVCVNGWSGVDCSENLNDCLEASCREGSTCIDRVAS-FICLCPRGKTGLLCHLTDACMSNPCRDGSQCDTNPITGNFNCNCPPGYVGNTCNIDRNECSI----GTNPCEHGGQC-VNTDGSFTCNCAKGYTGPRCEQDVNE-----CASSPCQNDGTC--LDRIGEYSCICMSGFTGSHCEIEVDECLSSPCLN 511 HSP 5 Score: 94.7449 bits (234), Expect = 1.581e-15 Identity = 82/267 (30.71%), Postives = 120/267 (44.94%), Query Frame = 2
Query: 365 GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINI-KIPKTFNEKQLIIKKTKSPSLC----DNLCKASFENGICDQQCNTFAC----NYDGGDCD 1135
G+CV D F C+C G+ G CE++VN+C +PC+N GTC+D+ +++C C S F G+ C+ E + CL+ C N G C + F C+C GF GE C + C P C N +C PN C+C G+TG C + + C C +G + CEC+ +TG C I ++E N + N Q + S S C D+ + E+G C N++ C Y G CD
Sbjct: 437 GQCVNT-DGSFTCNCAKGYTGPRCEQDVNECASSPCQNDGTCLDRI-GEYSCICMSGFTGSHCEIEVDECLSSPCLNQGKCLD-QVSHFVCECPAGFSGEVCQIDIDECSSTP------CLNGAKCIDRPN-GYDCECAEGFTGLLCQENIDDCTPAPCHYGVCHDG-------IATFFCECESGYTGSICNIQVQECHSNPCQNQGRCIDLVNAYQCNCQPGTSGSNCEINEDDCANSPCEHGECQDGINSYRCVCSPGYTGSKCD 686 HSP 6 Score: 94.3597 bits (233), Expect = 1.920e-15 Identity = 63/180 (35.00%), Postives = 79/180 (43.89%), Query Frame = 2
Query: 401 CSCWHGWKGETCEENVNDCI--QNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C+C G+ G+ C+ N NPC NGGTC ++ C CT + G C+ E+ CL+ C NGG C S G + C C G+ G C + C P LC N GEC P + C C G+TG C+ I C C NGG C S C C F G NC
Sbjct: 95 CTCPLGYTGQRCQTPQNSTCYPNNPCANGGTCTLLSLDKYKCECTRGWTGPHCEHEDSCLSDPCANGGRCSSQSGGRYTCHCPPGYKGPRCLIDRDECAETPS----LCQNDGECFNTPG-SYKCVCKAGFTGRLCESSY-----IPCSPSPCLNGGTCHQTSETSYSCHCLPGFNGTNC 264 HSP 7 Score: 94.3597 bits (233), Expect = 2.019e-15 Identity = 68/202 (33.66%), Postives = 101/202 (50.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLC-QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C+N PC +G+C + + +RC C G+ G C+ +N+C NPC +GGTC+D+ N F C C G LC + C C +G E + ++C+C G++G C + C P C N G C D + T C+C PG+TG+ C+K ++ C S C N GVC + S C C +TGK+C +
Sbjct: 655 CANSPCEHGECQDGIN-SYRCVCSPGYTGSKCDVEINECGSNPCMSGGTCMDQVNG-FYCLCPPNTHGPLCLSGTDHCARQPCVHGDCVE--QQLGYRCECEAGWVGAHCEQEKDECQPNP------CQNGGNCLDRHNGYT--CQCQPGFTGNNCEKNRDE-----CASSPCLNRGVC-IDGVNSYTCRCSPPYTGKHCEV 838 HSP 8 Score: 92.8189 bits (229), Expect = 6.051e-15 Identity = 68/211 (32.23%), Postives = 94/211 (44.55%), Query Frame = 2
Query: 347 NRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF------ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETR 958
N PC NG C +++C C GW G CE + C+ +PC NGG C + ++TC+C + G C E P L C+N G C + G ++C C+ GF G C I C P C N G C + C C PG+ G C+ + C C NGG C N + C+C E+TG++CT + E R
Sbjct: 117 NNPCANGGTCTLLSLDKYKCECTRGWTGPHCEHE-DSCLSDPCANGGRCSSQSGGRYTCHCPPGYKGPRCLIDRDECAETPSL---CQNDGECFNTP-GSYKCVCKAGFTGRLCESSYIPCSPSP------CLNGGTCHQTSETSYSCHCLPGFNGTNCENNID-----DCPEHQCANGGTCMDGVN-TYNCQCPPEWTGQHCTEDVDECR 310 HSP 9 Score: 92.0485 bits (227), Expect = 9.073e-15 Identity = 98/356 (27.53%), Postives = 139/356 (39.04%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCES------------------------------LENGM-------FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFAC----NYDGGDC-DPWRKCYGNDLKH---CKGVFND--GVCNPECNNVDCLFDGEDCHKSSC 1264
C + PC N E + C C G+ G+ C+ +++DC NPC NGG+C+DK + F+C C F G C+ E + C + C NG TC L NG F C+C GF+G FC ++ C P C N G C T C C GY+G C + CK +C NGG C S +C C+ +TG C +P N+ K + + +N+CK + G C N+ C Y G C DP +C N ++ CK + C P V+C +D ++CH C
Sbjct: 883 CLSDPCRNDGLCENRRGSYICKCQRGYSGQNCQTDIDDCKPNPCLNGGSCLDKV-AGFSCKCRPGFEGERCETEVDECASNPCRNGATCHDYVNSFVCACREGFRGIQCEHNIPECTESSCLNNGTCVDGINSFSCRCPLGFLGLFCEYESNECDSQP------CKNGGSC-TDGLRTYSCVCPVGYSGSNCQNYVNV-----CKGVHCLNGGTCS-QSTTSWVCRCQAGWTGLYCDVP----------NMSCQNFAARKGVDV---------ENVCKNA---GQCKNVGNSHQCICQPGYTGSYCEDPVDECLSNPCRNGATCKDYQGNYQCTCKPGFQGVNCEYDVDECHSRPC 1202 HSP 10 Score: 82.4185 bits (202), Expect = 8.954e-12 Identity = 75/249 (30.12%), Postives = 110/249 (44.18%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC-LNVN-CENGGTCESLENGMFQCKCRYGFIGEFCA--------------------VQNIACPVIPKKKREL------------CNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
CS PC+NG C + + + C C G+ G CE N++DC ++ C NGGTC+D N+ + C C ++ G C + + C L N C+NGGTC + G + C C G+ G C+ V + C + P+ K L C + +CD P F C C PGY G+ C+ + E ++ C +GG C V +GS C C +TG C + E N
Sbjct: 232 CSPSPCLNGGTCHQTSETSYSCHCLPGFNGTNCENNIDDCPEHQCANGGTCMDGVNT-YNCQCPPEWTGQHCTEDVDECRLQPNTCQNGGTCHN-GIGSYNCVCVNGWSGVDCSENLNDCLEASCREGSTCIDRVASFIC-LCPRGKTGLLCHLTDACMSNPCRDGSQCDTNPITGNFNCNCPPGYVGNTCNIDRN---ECSIGTNPCEHGGQC-VNTDGSFTCNCAKGYTGPRCEQDVNECASSPCQN 473 HSP 11 Score: 76.2554 bits (186), Expect = 5.681e-10 Identity = 71/233 (30.47%), Postives = 94/233 (40.34%), Query Frame = 2
Query: 467 PCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCE-SLENGM-----FQCKCRYGFIGEFCAV-QNIAC-PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQ---CNTFACNYDGGDC 1132
PC N TC+ N C C + F+G CQ E+PC C N GTC S+ +G+ C C G+ G+ C QN C P P C N G C + C+C G+TG C+ E C SD C NGG C G C C + G C I E + + + FN +P +CKA F +C+ C+ C +GG C
Sbjct: 34 PCVNNATCVTFGNGTEYCRCAAGFLGEYCQHEDPCQPGLCLNRGTCSVSMPDGVPVPGSALCTCPLGYTGQRCQTPQNSTCYPNNP------CANGGTCTLLSLDKYKCECTRGWTGPHCEH------EDSCLSDPCANGGRCSSQSGGRYTCHCPPGYKGPRCLIDRDECAETPSLCQNDGECFN----------TPGSYKCVCKAGFTGRLCESSYIPCSPSPC-LNGGTC 243 HSP 12 Score: 73.559 bits (179), Expect = 3.572e-9 Identity = 65/203 (32.02%), Postives = 89/203 (43.84%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP--CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCT 937
C + PC NG +C + C C G+KG C + ++C + P C+N G C + S + C C + F G LC+ PC C NGGTC + C C GF G C CP C N G C N T C+C P +TG C + + E + + C NGG C GS C C ++G +C+
Sbjct: 153 CLSDPCANGGRCSSQSGGRYTCHCPPGYKGPRCLIDRDECAETPSLCQNDGECFNTPGS-YKCVCKAGFTGRLCESSYIPCSPSPCLNGGTCHQTSETSYSCHCLPGFNGTNCENNIDDCP------EHQCANGGTCMDGVN-TYNCQCPPEWTGQHCTEDVD---ECRLQPNTCQNGGTCHN-GIGSYNCVCVNGWSGVDCS 343 HSP 13 Score: 71.2478 bits (173), Expect = 1.979e-8 Identity = 80/330 (24.24%), Postives = 124/330 (37.58%), Query Frame = 2
Query: 398 RCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGV--CKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSF 1378
+C C G+ G CE+ V++C+ NPC+NG TC D + + + C C F G C+++ + C + C NGG C +L N F C C G G C V C P C N G+C + C C PG+ G+ C+ C+S C G C L N C C+ +TG++C E+++N+ + K + + S C + C + + N C + CL G H + +C + +C+ E +GG C +N F
Sbjct: 1140 QCICQPGYTGSYCEDPVDECLSNPCRNGATCKDYQGN-YQCTCKPGFQGVNCEYDVDECHSRPCLNGGRCINLIN-RFTCSCPPGTHGVQCEVNEDDCAPQPGSSEPRCLNGGQC-VDGVGRYTCSCPPGFVGEHCEGDVNE-----CRSAPCHGPGTLDCVELVNDY-RCLCRLGYTGRHC---------ESMVNLCVSKPCRNGGVCSMNSSSVRGYTCSCPPGYTGSTCAE-----------------------------------LQNHSCGGLRCLNGGSCLHHNGQPLCQCPPGFSGPLCENEQRCSVTCHNGGTCVKDPANPF 1416
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: H2V8L9 (Notch receptor 2 OS=Takifugu rubripes OX=31033 GN=LOC101080224 PE=4 SV=2) HSP 1 Score: 225.713 bits (574), Expect = 9.104e-56 Identity = 244/945 (25.82%), Postives = 397/945 (42.01%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNP------CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT----LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC-------------TIPLKETRKEALINIKIPKTFNEKQLIIKKTKS-PSLCDNL-CKASFENGICDQQCNTFACNYDGGDCD-----PWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHK-SSCKFHK-CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTVFNVTEINFNF------------ATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQH---RHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLE-STDGIHPIDAGLGDVYT---MASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLH----------------------SLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C ++PC++G F C C G G CE NV+DC P C NGG C+D ++TC+C F+G C+ + N CL+ C G+ C L N +QC+CR G+ G C C P C N G C + NMT C C PG+ G C + + C +C NGG C G C+C+ F+G +C +K++ + P F+ + S PS C L CK + +CD QCN C++DGGDC PW C + C +F +G C+ EC+N CLFDG +C K +CK+ K C++ + NKICD C + CG+DG DC + Q K DL Y + ++ ++ MV F V ++ L ++ +C G+CFS E++++FL A K + LP+ L V++ ++ + Y + ++ ++LL + + ++ + K G L W P + G LK+FK Q L G+SQ + R + +P P++++ + E ++ +A L E +DG+ ++ D +T +AS++N D E G + I+ ++ GA++I Q + + LH + D GRTPL +++AADA + Q+LI + +S+ N TT LI A +L + M+ L+ + +N +D G+S +HW+A NN +E + D++DN++++PLFLAA EG+ ++ + LL +++ I MD P+ A+E+ ++I L+ +
Sbjct: 1198 CHSKPCLHGGTCINLINRFTCVCPSGTHGVQCEVNVDDCAPKPGSWEPRCLNGGQCLDGI-GRYTCSCPPGFVGEHCEGDLNECLSGPCHATGSLDCVQLVND-YQCRCRLGYTGRHCDSMVDLCLSKP------CRNGGVCSM--NMTSVHGYMCSCPPGFIGFNCGEIEGYT----CAKLHCQNGGRCVESAGGHLYCQCQQGFSGAHCENSQWCPWPCQNGGTCMKDSANPVQYSCHCPNNFSGRYCENNVVGSGPSTCPYLQCKHHSADKVCDAQCNNHECDWDGGDCSLNWKQPWSNCTAS--VSCWDLFKNGRCDKECDNPGCLFDGFECQKHKTCKYEKYCADHFGNKICDPSCYTKACGWDGLDCAGDTPAKIVPGTLVIVVLLQPKELLGDLRGFLRSLGALLYTNLQVKLDENNKPMVYPYFGVENHGQQLKGSRSKRELEKEVIGSVVHLEIDNRKCSESSGECFSKTEEVASFLAAAHIKAD---LPYPLVSVNSSPAVPIRETHILPYLVGVSVVILLLIVVLGMLAAKRKHKHGLL---------WLPDGFMANKNDKRRE--PVGQDDF-DLKNFKT--QDGAVLDGGQSQRWLEDEVPPRKPRLEGKPLLPMAMDGGVDRREWTRQHRKAADISLTPPQAELDSDGVD-VNVKGPDGFTPLMLASLRNGGVLDCNLHGDEEEESGGDEPGSSV----ISDLISQGASLIAQTDRTGETALHLAARYARADAAKRLLDAGADPNAHDNMGRTPLHAAVAADA-QGVFQILIRNRATELDSRMN-------------------DGTTPLILAARLAVEGMVEELIHCHADINAVDDHGKSALHWAAAVNN---VEATLVLLKNGANRDMQDNKEETPLFLAAREGSFEAAQVLLDHYSNRDITDHMDRL---PRDTAQERMHHDIVRLLDQ 2078 HSP 2 Score: 112.464 bits (280), Expect = 6.204e-21 Identity = 94/311 (30.23%), Postives = 132/311 (42.44%), Query Frame = 2
Query: 314 LLVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS-------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTF-NEKQLIIKKTKSPSLCDN---LCKAS--FENGICDQQCNTFAC 1111
LL + + C +PCV+GKC+E + F C C GW G+ CE+ ++C+ NPC+N G+C+D+ N +TC C F G C+ E +PC + C+ GG C S + F C+C G+ G C+ C K+ C N G C P + CKC GY+G C + C + C NGG C V D GS CEC+ F G++C I E + N I + + N + LCD+ C S NG C NTF+C
Sbjct: 721 LLCLSGTDHCVAQPCVHGKCIEQQNGYF-CQCEAGWVGQHCEQEKDECLPNPCQNSGSCLDRHNGFTCVCQAGYRGVNCEKNIDECTSGPCLNQGICIDGLNSYTCQCVPPFAGEHCEVELDPCSSRPCQRGGVCLPSADYTYFTCRCPAGWQGLHCSEDVNEC------KKNPCRNGGHCINSPG-SYICKCPSGYSGHNCQTDID-----DCSPNPCLNGGSC-VDDVGSFSCECRPGFEGEHCEIEADECASQPCRNGAICRDYVNSFVCECRLGFDGILCDHNILECTESSCLNNGTCIDDINTFSC 1017 HSP 3 Score: 98.9821 bits (245), Expect = 7.326e-17 Identity = 72/260 (27.69%), Postives = 110/260 (42.31%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE---------------------------------------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+ + C+++PC NG + F C C G+ G C+ N+ +C ++ C N GTCID N+ F+C C F G C++E N C V C NGG+C + C C G+ G +C V +++C +K +C N G C + + C+C PGYTG C++ + CKS+ C NG CK G+ C CK + G NC + E + ++
Sbjct: 954 IEADECASQPCRNGAICRDYVNSFVCECRLGFDGILCDHNILECTESSCLNNGTCIDDINT-FSCRCLPGFFGTFCEYEQNECDSQPCKNGGTCTDGLGTYRCTCPAGYNGQNCQNYVNLCRQVRCHNGGSCSHTGATSWTCHCTMGWTGPYCDVPDMSCRDFAARKGLEEENVCKNAGRC-VNVGNSHKCECQPGYTGSYCEEMVDE-----CKSNPCRNGATCKDY-QGTYECICKPGYQGVNCEYEVDECHSKPCLH 1205 HSP 4 Score: 98.2117 bits (243), Expect = 1.416e-16 Identity = 78/220 (35.45%), Postives = 103/220 (46.82%), Query Frame = 2
Query: 341 CSNRPCVNGK-CVEAFD-PEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
CS+RPC G C+ + D F C C GW+G C E+VN+C +NPC+NGG CI+ S + C C S + G+ CQ + NPCL NGG+C + G F C+CR GF GE C ++ C P C N C Y N + C+C G+ G CD + C C N G C + D + C C F G C E + N
Sbjct: 843 CSSRPCQRGGVCLPSADYTYFTCRCPAGWQGLHCSEDVNECKKNPCRNGGHCINSPGS-YICKCPSGYSGHNCQTDIDDCSPNPCL-----NGGSCVD-DVGSFSCECRPGFEGEHCEIEADECASQP------CRNGAICRDYVN-SFVCECRLGFDGILCDHNI-----LECTESSCLNNGTC-IDDINTFSCRCLPGFFGTFCEYEQNECDSQPCKN 1042 HSP 5 Score: 89.7373 bits (221), Expect = 4.792e-14 Identity = 60/180 (33.33%), Postives = 78/180 (43.33%), Query Frame = 2
Query: 401 CSCWHGWKGETCE--ENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
CSC G+ G+ C+ +N NPC N G C ++ C C + G C++E+ CL+ C NGGTC +L G + C C G+ G C C P +C N G C I + C C G+TG C+ I C C NGG C S C C F G NC
Sbjct: 95 CSCPLGYAGQHCQIPQNSTCYPNNPCANRGICTLLPFDKYKCECARGWTGPGCEYEDSCLSSPCANGGTCSTLSGGSYTCSCLPGYTGRHCLNDTDECAATPS----ICQNEGTC-INTRGSYKCMCALGFTGKHCESSY-----IPCSPSPCLNGGTCNQNSETSYSCHCLPGFNGTNC 264 HSP 6 Score: 86.6557 bits (213), Expect = 4.087e-13 Identity = 68/180 (37.78%), Postives = 93/180 (51.67%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVC 871
CS+ PC+NG KC++ + + C C G+KG CEEN+NDC+ PC + G C D + F+C C + + G +C + C + C+N G C L N +QC C G G C + C LC +GEC N C C PGYTGD+CD V+I C S+ C +GG C
Sbjct: 542 CSSTPCLNGAKCIDLPN-GYDCECAEGFKGLLCEENINDCVPEPCHH-GQCKDGI-ATFSCECYAGYTGAICNIQVQECHSNPCQNRGRCIDLVN-AYQCNCPPGISGVNCEINEDDC------ASNLC-VYGECQDGIN-EYKCVCSPGYTGDKCD------VDINECSSNPCMSGGTC 703 HSP 7 Score: 85.5001 bits (210), Expect = 1.025e-12 Identity = 65/206 (31.55%), Postives = 91/206 (44.17%), Query Frame = 2
Query: 347 NRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLC---QFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
N PC N G C +++C C GW G CE + C+ +PC NGGTC +TC+C + G C E C+N GTC + G ++C C GF G+ C I C P C N G C+ + C C PG+ G C+ + C C N G C + + C+C E+TG++CT + E
Sbjct: 117 NNPCANRGICTLLPFDKYKCECARGWTGPGCEYE-DSCLSSPCANGGTCSTLSGGSYTCSCLPGYTGRHCLNDTDECAATPSICQNEGTCINTR-GSYKCMCALGFTGKHCESSYIPCSPSP------CLNGGTCNQNSETSYSCHCLPGFNGTNCENNID-----DCPGHQCANRGTC-IDGVNTYNCQCPPEWTGQHCTEDVNE 308 HSP 8 Score: 83.5741 bits (205), Expect = 3.605e-12 Identity = 67/209 (32.06%), Postives = 94/209 (44.98%), Query Frame = 2
Query: 353 PCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
PC +G + F C+C G+ G CE++VN+C NPC+N GTC+D+ ++C C F G C+ E N CL+ C N G C + F C+C GF GE C + C P C N +C PN C+C G+ G C++ V C C +G + CEC +TG C I ++E N
Sbjct: 432 PCEHGGQCVNTEGSFTCNCAKGYAGPRCEQDVNECASNPCQNDGTCLDRI-GDYSCICMPGFGGTHCENELNECLSSPCLNRGKCLD-QVSRFVCECPAGFSGEMCQIDIDECSSTP------CLNGAKCIDLPN-GYDCECAEGFKGLLCEENINDCVPEPCHHGQCKDG-------IATFSCECYAGYTGAICNIQVQECHSNPCQN 624 HSP 9 Score: 81.6481 bits (200), Expect = 1.367e-11 Identity = 93/323 (28.79%), Postives = 133/323 (41.18%), Query Frame = 2
Query: 455 CIQN--PCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCE-SLENGM-----FQCKCRYGFIGEFCAV-QNIAC-PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLC-----DNLCKASF---------ENGICDQQCNT-FACN----YDGGDCD-PWRKCYGNDLKHCKGVFNDGV------CNPECNNVDCLFDGEDCH--KSSCK-FHKCSELYQNKIC 1306
C+ N PC N TC+ N C C F+G CQ ++PC C NGG C S+ G+ C C G+ G+ C + QN C P P C N G C + P C+C G+TG C+ E C S C NGG C L GS C C +TG++C E I NE I + +C C++S+ G C+Q T ++C+ ++G +C+ C G+ + +G DGV C PE C D +CH ++C+ CS L+ + +C
Sbjct: 28 CMDNKAPCVNNATCVTLNNRTEYCRCAPGFLGEYCQHKDPCQPGYCLNGGNCSVSMSAGVPVPGSATCSCPLGYAGQHCQIPQNSTCYPNNP------CANRGICTLLPFDKYKCECARGWTGPGCE------YEDSCLSSPCANGGTCSTLSGGSYTCSCLPGYTGRHCLNDTDECAATPSI------CQNEGTCINTRGSYKCMCALGFTGKHCESSYIPCSPSPCLNGGTCNQNSETSYSCHCLPGFNGTNCENNIDDCPGHQCAN-RGTCIDGVNTYNCQCPPEWTGQHCTEDVNECHLQPNTCQNGGTCSNLFGSYVC 331
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Match: A0A1A9W977 (Uncharacterized protein OS=Glossina brevipalpis OX=37001 PE=4 SV=1) HSP 1 Score: 224.942 bits (572), Expect = 1.572e-55 Identity = 239/958 (24.95%), Postives = 400/958 (41.75%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGT--CIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP-------LKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHKCSELYQ--------NKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTV----------------FNVTEI-NFNFA-------------TALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDK--------W------------GKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKL---PQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAF--QLISDSLESTDGIHPIDA----GLGDVYTMASVKNHMKYDEKYQTSS-----------LEG--LGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLIQETLRK 2953
NG C++ F C+C G+ G CE ++N+C+ NPC N GT C+ N+ + CNC ++G C+ + + C N C+NGG C S + G C C GF G+ C C P + G C I C C G G C E+ C + C G C L G +C C ++TGK C I + ++ + AL N ++++ +K+ C+ N ICDQ+CNT+ACN+DG DC +PW C C VF DG+CN ECN+ CL+DG DC K K C+ +Y N CD C++ +C +DG DC ++ ++ +V++ ++ F + + FL+++ LR V + +T+I N +FA T + I L ++ +C +CF+ + + FL A I LS F + V +E P + ++L ++ L GVL+ + W + R + +G + + S + +++ N + PQ D + + P +L R+ HG D+ + + + ++ H +A I DG H +D G+ + A + E ++S +G L +++ GE+ +H+AAR + ++A + + D GRTPL +++ ADA Q+L+ + ++ N TT LI AV+L ++M+ L+ + +N D+ GR+ +HW+A NN+ E L+ + + D +D++D++PLFLAA EG+ S K LL F I +C P+ +A E+ ++I L+ E + +
Sbjct: 1007 NGTCIDRVG-SFECACPPGFVGSRCEGDINECLSNPCSNAGTLDCVQLVNN-YHCNCKPGYMGRHCENKVDFCANSPCQNGGIC-SPKQGGHHCVCAEGFYGKNCEFSGHDCDSNPCQA-------GSCVIDDGGGYRCICPRGTEGRHC----EIDTMDECSPNPCLQGAACDNL-LGDFVCFCPSKWTGKRCEIHDPKYPGWVSDSSRGAL-NKYAKDLEYQREMCVKRG---------CEQKKGNHICDQECNTYACNFDGNDCSLGINPWVNCTA--PIECWRVFMDGICNEECNDAACLYDGRDCEK---KLQPCNPVYDAYCQKHYANGFCDYGCDNAECNWDGLDCENESKPPKLADGAIS------------VVMLMDIKQFREQQVVFLREIGHLLRTTVRIKKDSMGNDMIFTWKGSSQLTDIQNTDFARRHKILFTERNGQTGIQIYLEIDNRKCT----ECFNRAAEAAEFLGA-IASKYTLSSKFPIYSVRGVQNPGEDVEETPTNVKYVTTGVILVVLAFALSGVLVTTQRKRAHGITWFPEGFRTPTTAINRQRRRRDPSGQEMRNLNKNPSIACMSNDVNMNSGHIGHAPQWSDDESDMPQPKRL------------RNDHGGYASDHTMVTDYEEADQRVWSQAHLDVAGVRSSIMTPPAHQDGKHDVDVRGPCGMTPLMVAAVRGGGIDSGEDIESSDDIAAQVIADLIAQGAQLNAVMDKTGETPLHLAARYARADAAKRLLDA--GADANCEDSTGRTPLHAAVGADAV-GVFQILLRNRATNLNARMN-------------------DGTTPLILAVRLAIEDMVEKLITADADINAADNTGRTALHWAAAVNNT---EALNILLMHHANRDAQDDKDETPLFLAAREGSYGSCKALLDNFANREITDHMDCL-PRDVAAERLHHDIVRLLDEHVPR 1879 HSP 2 Score: 101.679 bits (252), Expect = 1.182e-17 Identity = 78/247 (31.58%), Postives = 112/247 (45.34%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLN---------------------------------VNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKR----ELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C + PC NG + + C+C G+ G C+ N DC ++ C NGGTCID NS + C+C F G+ CQ++ PC N CENG TC ++N F C+C G+ G+ C V+ ++C +K +LCNN G C + N+ C C GYTG C ++ C+S C NGG C+ L GS C C+ F G+NC + + +
Sbjct: 724 CLSMPCQNGATCRQYVNSYTCTCPLGFSGINCQTNDEDCTESSCMNGGTCIDGINS-YNCSCLPGFTGSNCQYKINKCDSQPCQNGATCHENNDEYTCHCSYGYTGKQCTDYVDWCTKSPCENGATCTQVKN-QFSCRCAPGWTGKLCDVEMVSCRDAALRKAVPLDQLCNN-GTCKEHGNIHR-CYCKQGYTGSYCQQEINE-----CESQPCLNGGTCRDLI-GSYACVCRKGFQGQNCELNIDD 960 HSP 3 Score: 95.5153 bits (236), Expect = 8.418e-16 Identity = 70/202 (34.65%), Postives = 98/202 (48.51%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C++ PC+NG E EF C C G+ G+ CE ++++C NPC++GG C+D+ N+ F C C + G C+ + C+N C NGGTC NG ++C C+ + G C + C C N C PN F C C GYTG CD+ ++ S C NG C L GS C C + G +C I
Sbjct: 493 CASNPCINGGRCEDGVNEFICHCSPGYGGKRCEIDIDECSSNPCQHGGICVDELNA-FKCQCMPGYTGYKCEINIDDCVNNPCANGGTCIDKVNG-YKCVCKVPYTGIDCESKLDPCAT------NRCRNDAMCTPSPNFLDFSCTCKLGYTGRYCDED----IDECSLSTPCRNGATCLNLP-GSYRCICAKGYEGHDCAI 681 HSP 4 Score: 92.8189 bits (229), Expect = 4.753e-15 Identity = 69/196 (35.20%), Postives = 87/196 (44.39%), Query Frame = 2
Query: 353 PCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCT 937
PC NG +RC C G++G C N +DC PC+NGGTC+D + C C F G C+ + N CL++ C+NG TC N + C C GF G C + C C N G C I + C C PG+TG C K C S C NG C +N C C +TGK CT
Sbjct: 652 PCRNGATCLNLPGSYRCICAKGYEGHDCAINTDDCASFPCQNGGTCLDGI-GDYYCLCVDGFDGKHCETDINECLSMPCQNGATCRQYVNS-YTCTCPLGFSGINCQTNDEDC------TESSCMNGGTC-IDGINSYNCSCLPGFTGSNCQYKINK-----CDSQPCQNGATCHE-NNDEYTCHCSYGYTGKQCT 832 HSP 5 Score: 89.3521 bits (220), Expect = 6.295e-14 Identity = 65/211 (30.81%), Postives = 91/211 (43.13%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLE-NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKI 985
C NG + C C +GW G C EN++DC C NG TC+D S F C C G LC ++ C + C C++ NG + C C G+ G C+ C + C ++G C P + C C G+TG RC+ C+S C N G C + D G+ C C FTG C I + E + +N +
Sbjct: 79 CKNGATCTNSPGSYSCICVNGWNGTDCSENIDDCATASCLNGATCVDGVGS-FYCRCAPGKTGLLCHLDDACTSNPCHADAICDTSPINGSYTCSCAAGYKGVDCSEDIDEC-----DQGSPCEHNGICVNTPG-SFMCNCSQGFTGPRCETNINE-----CESHPCQNEGSC-LDDPGTFRCVCMPGFTGTQCEIDIDECQSNPCLNDGV 276 HSP 6 Score: 87.8113 bits (216), Expect = 1.607e-13 Identity = 71/228 (31.14%), Postives = 102/228 (44.74%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCN---------------------NHGECDIYP---------NMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
NG CV F C+C G+ G CE N+N+C +PC+N G+C+D + F C C F G C+ + + C + C N G C + +G F+C C +GF G C + C P + +C+ N +CD P + + C CDPG+TG C + C+S+ C GG C V GS IC C +GK+C I + E
Sbjct: 198 NGICVNTPG-SFMCNCSQGFTGPRCETNINECESHPCQNEGSCLDDPGT-FRCVCMPGFTGTQCEIDIDECQSNPCLNDGVCHDMISG-FKCSCAFGFTGSRCQINIDDCHSQPCRNNGICHDSIGGYTCECPPGYTGLSCEININDCDSNPCHRGKCIDGDNSFKCVCDPGFTGYLCQTQINE-----CESNPCQYGGHC-VDRVGSYICHCLPGTSGKDCEINVNE 416 HSP 7 Score: 77.0258 bits (188), Expect = 3.333e-10 Identity = 67/218 (30.73%), Postives = 88/218 (40.37%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF------ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC+N F+CSC G+ G C+ N++DC PC+N G C D +TC C + G C+ NPC C +G + F+C C GF G C Q C P C G C + + C C PG +G C E+ V C S+ C NG C N C C FTG +C I + E N
Sbjct: 266 CQSNPCLNDGVCHDMISGFKCSCAFGFTGSRCQINIDDCHSQPCRNNGICHDSIGG-YTCECPPGYTGLSCEININDCDSNPCHRGKCIDG-------DNSFKCVCDPGFTGYLCQTQINECESNP------CQYGGHC-VDRVGSYICHCLPGTSGKDC----EINVNE-CHSNPCNNGATCIDGIN-KYTCNCVPGFTGVHCEININECASNPCAN 462 HSP 8 Score: 74.3294 bits (181), Expect = 2.461e-9 Identity = 60/203 (29.56%), Postives = 93/203 (45.81%), Query Frame = 2
Query: 416 GWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF---ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKETRKEAL-----INIKIPKTF 997
G++G+ CE N++DC N C+NGGTCID S ++C+C + G CQ E ++ C+NG TC + G + C C G+ G C+ I C N C + + +C+C PG TG C ++ C S+ C +C NGS C C + G +C+ + E + + I + P +F
Sbjct: 21 GFQGKHCEHNIDDCPGNQCQNGGTCIDGITS-YSCSCPPNYTGEYCQTDVDECAIMSSVCKNGATCTN-SPGSYSCICVNGWNGTDCSEN------IDDCATASCLNGATC-VDGVGSFYCRCAPGKTGLLCH------LDDACTSNPCHADAICDTSPINGSYTCSCAAGYKGVDCSEDIDECDQGSPCEHNGICVNTPGSF 208 HSP 9 Score: 71.633 bits (174), Expect = 1.713e-8 Identity = 69/219 (31.51%), Postives = 94/219 (42.92%), Query Frame = 2
Query: 341 CSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC-IDKKNSQFTCNCTSQFIGNLCQFE-NPC-LNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKI 985
C+ C+NG CV+ F C C G G C + + C NPC C N +TC+C + + G C + + C CE+ G C + G F C C GF G C C P C N G C P T C C PG+TG +C E+ ++ C+S+ C N GVC + +G C C FTG C I + + + N I
Sbjct: 112 CATASCLNGATCVDGVG-SFYCRCAPGKTGLLCHLD-DACTSNPCHADAICDTSPINGSYTCSCAAGYKGVDCSEDIDECDQGSPCEHNGICVNTP-GSFMCNCSQGFTGPRCETNINECESHP------CQNEGSCLDDPG-TFRCVCMPGFTGTQC----EIDIDE-CQSNPCLNDGVCHDMISGFK-CSCAFGFTGSRCQINIDDCHSQPCRNNGI 314 HSP 10 Score: 70.0922 bits (170), Expect = 4.752e-8 Identity = 80/322 (24.84%), Postives = 127/322 (39.44%), Query Frame = 2
Query: 338 LCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACP-VIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPIC--ECKG---EFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCD-PWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSS 1261
C+N PC NG C C G+ G+ CE + +DC NPC+ G+C+ + C C G C+ + NPCL G C++L G F C C + G+ C + + P + R N + + D+ + ++E+ V+ GC+ G+ IC EC F G +C++ + +N P C F +GIC+++CN AC YDG DC+ + C +C+ + +G C+ C+N +C +DG DC S
Sbjct: 1076 FCANSPCQNGGICSPKQGGHHCVCAEGFYGKNCEFSGHDCDSNPCQ-AGSCVIDDGGGYRCICPRGTEGRHCEIDTMDECSPNPCL-----QGAACDNLL-GDFVCFCPSKWTGKRCEIHDPKYPGWVSDSSRGALNKYAK-DL-------------------EYQREMCVKRGCEQ------------KKGNHICDQECNTYACNFDGNDCSLGIN-----PWVNCTAPIE--------------------CWRVFMDGICNEECNDAACLYDGRDCEKKLQPCNPVYDAYCQKHYANGFCDYGCDNAECNWDGLDCENES 1333
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: notch1b (neurogenic locus notch homolog protein 1-like [Source:NCBI gene;Acc:103025197]) HSP 1 Score: 202.986 bits (515), Expect = 4.085e-52 Identity = 244/1010 (24.16%), Postives = 404/1010 (40.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS---------------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP---------------LKETRKEALINIKIPKTFNE--------------KQLIIKKTKSPSLCD-NLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTS----RSNSF------FSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFL-------------QKLSSSLRMVVTVFNVTEINFNFATAL--LIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPK--LPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDS----------------LESTDGIHPI------DAGL--GDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C PC NG + + C C G+ G C +N+C+ PC+NGGTCID N+ + C C ++G C+ + N CL+ C+ GT C L N ++C+CR G+ G+ C V K + C N G C + N CKC PG+TG C+ + C S C NGG C V + +P C C FTG C P + + + + P FN + I + + C+ C+A N CD CN+ C++DGGDC DPW+ C +D C FN+G C+ +C++ CL+DG DC +S + + C + Y + CD+ CN+ +C +DG DC + R+ E L ++ L EL VL T + + E + SL V+ + + + ++ L ++ QC +CF S ++ FL A GN L+LP+ +A + + + P+Y ++ + LL F + R + G+L W P ++ S G L LK+ N+ +GE +P D R + +Q + +++++ + ++ A ++ S + + DG P+ GL G+ ++ D YQ ++L + GE+ +H+AAR + + A + + D GRTPL +++AADA + Q+LI + +++ + TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL +F I MD P+ IA+E+ ++I L+ E
Sbjct: 1148 CIPNPCQNGATCTDYLGGYSCECVPGYHGVNCSSEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRCVDRVGGYHCVCPPGYVGERCEGDVNECLSNPCDPRGTHSCIQLTNN-YRCECRTGYTGQRCDT------VFDGCKGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAQ-----ACGSLQCKNGGTC-VSGHKNPRCLCSPSFTGPECQYPSDGPCLSNPCYNGGTCEPSTESPYFHCVCPADFNGLLCHILDYGFTGGFGRDITPPPEVEASCEIPECEAKKGNKECDAACNSHECDWDGGDCSLNFRDPWQNC--SDALQCWRYFNNGKCDEQCHSAGCLYDGFDCQRSGGECNPLYDQYCKDHYADGHCDQGCNNAECEWDGLDCADNVPEKRATGLLVLVVHLPPEQLRN-NSSGFLRELSRVLHTNIVFRQDTQGELMIYPYYGSPHELRKHNKKRSLDSWSDVYGSGRRDQDQTQVVGSVVYLEIDNRQCYQQSAECFQSATDVAAFLGALASSGN-LNLPYVMAVTSESEVPPT-TELYPLYVVLASVALLAFVAVGMVASRKRRREHGQL---------WFPDGFKTSEPSKKKRREPVGEDSVGLKPLKNSDISLMDDNQNEWGEEEP-VDTKRFRYEEQA---MLDLDDQQDHRQWTQQHLDAADLRIPSVAPTPPQGEIENDCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDASANVINDFIYQGANLH---NQTDRTGETALHLAARYARSDAAKRLLEASADANIQ--DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDARMH-------------------DGTTPLILAARLAVEGMVEELINCHADVNAIDDFGKSALHWAAAVNNVDAAVVLLKNGANK---DMQNNKEETPLFLAAREGSYETAKVLLEHFANREITDHMD---RLPRDIAQERMHHDIVRLMDE 2095 HSP 2 Score: 108.612 bits (270), Expect = 3.009e-23 Identity = 120/434 (27.65%), Postives = 171/434 (39.40%), Query Frame = 2
Query: 332 SKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVI--PKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDK-----------------------------------KKELPVEIGCKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGIC----DQQCNTFACNYDGGDCDP--------------------------WRKCYGNDLK------------HCKGVFNDGVCNPECNNVDCLFDGEDCH-------KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTS 1363
++LC N +G C++A + + C C G+ G CEE V++CI NPC+NG TC D ++C C + G C E N CL+ C+NGGTC L N ++C C G G C + C P K C N G C + C C PGY G+RC+ ++ V GCK C NGG C V N +P IC+C FTG C E +A +++ + K+P LC SF C D C + C Y+GG C+P + +G D+ C+ + C+ CN+ +C +DG DC ++ +C + N CDE+C+S C +DG DC S
Sbjct: 1112 ARLCRN----SGLCLDAGNTHY-CQCQAGYTGSYCEEQVDECIPNPCQNGATCTDYLGG-YSCECVPGYHGVNCSSEINECLSQPCQNGGTCIDLVN-TYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRC-VDRVGGYHCVCPPGYVGERCEGDVNECLSNPCDPRGTHSCIQLTNNYRCECRTGYTGQRCDTVFDGCKGKPCRNGGTCAVASN-TPHGFICKCPPGFTGSTC-----EYDAQACGSLQC----KNGGTCVSGHKNPRC---LCSPSFTGPECQYPSDGPCLSNPC-YNGGTCEPSTESPYFHCVCPADFNGLLCHILDYGFTGGFGRDITPPPEVEASCEIPECEAKKGNKECDAACNSHECDWDGGDCSLNFRDPWQNCSDALQCWRYFNNGKCDEQCHSAGCLYDGFDCQRS 1523 HSP 3 Score: 97.4413 bits (241), Expect = 7.891e-20 Identity = 71/218 (32.57%), Postives = 105/218 (48.17%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C+ C NG CV+ + F C C G+ G C+ ++N+C PC NGGTC D + + C C + G CQ N C C+NGGTC + C+C+ G+ G +C V +++C V K++ LC N G C + T +C+C GYTG C+++ + C + C NG C G CEC + G NC+ + E + N
Sbjct: 986 CTESSCFNGGTCVDGIN-TFSCLCLAGFTGSYCQHDINECDSKPCMNGGTCQDSYGT-YKCTCPHGYRGFNCQELVNWCKPSPCKNGGTCRQ-SGTTYTCQCQTGWTGLYCDVPSVSCEVAAKQQGVEVARLCRNSGLC-LDAGNTHYCQCQAGYTGSYCEEQVDE-----CIPNPCQNGATCTDYLGGY-SCECVPGYHGVNCSSEINECLSQPCQN 1193 HSP 4 Score: 95.9005 bits (237), Expect = 2.306e-19 Identity = 76/252 (30.16%), Postives = 106/252 (42.06%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC G C ++ F C C G+ G CE N+N+C+ +PC+NGGTC D++N+ + C C + G LC + C C NGGTC NG F C+CR G+ C Q C P I HG C+ N C CD G++G+ CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 569 CLSNPCHYGLCKDSL-AGFTCHCRAGYTGRLCEANINECLSHPCQNGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQSNPCDFGKCIDKINGYECACEPGYTGKLCSINIDECAINPCHNGGTCIDGVNG-FMCQCRDGYHDPTCQSQLNECLSNPCI----------HGHCEDRVN-GYNCICDSGWSGNNCDINNNE-----CESNPCMNGGTCKDMTSGY-VCSCRAGFSGPNCQTNINECASNPCLN 801 HSP 5 Score: 90.1225 bits (222), Expect = 1.505e-17 Identity = 74/227 (32.60%), Postives = 104/227 (45.81%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC--LNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEK 1006
CS PC++G CV+ + + CSC G+ G+ CEEN++DC + C NGGTC+D N+ + C C ++ G C + N C + +C+NGGTC + + G + C C G+ GE C+ I CN C + FC+C PG TG C + C S+ C G C NG IC C + G C + E A K N K
Sbjct: 221 CSPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNT-YNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGG-YNCVCVNGWTGEDCSKN------IDDCADAACNVGATCHDRV-ASFFCECPPGRTGLLCH------LNDACISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECSLGANPCEHAGKCLNTK 432 HSP 6 Score: 88.1965 bits (217), Expect = 4.703e-17 Identity = 81/278 (29.14%), Postives = 116/278 (41.73%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPLKETRKEALIN------------IKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFAC 1111
+++ C + PC+NG + + CSC G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ +PC C+N G C ES + F C C G+ G+ C + C P + C N + C C GYTG C+ + CK + C NGG CK +G + C C F G C + E N P F+ I + +P ++ C F G C NTF+C
Sbjct: 751 INNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCLLPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNPCRNGATCQNS-------IGSYRCSCKSGYTGRNCETDID-----DCKPNPCSNGGFCK---DGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNGANCTDCVNSYTCTCPPGFSG---INCENNTPDCTESSC---FNGGTCVDGINTFSC 1006 HSP 7 Score: 85.8853 bits (211), Expect = 2.814e-16 Identity = 82/283 (28.98%), Postives = 122/283 (43.11%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQF-TCNCTSQFIGNLCQFENPCLNVNCENGGTCESL--ENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACN----YDGGDCDP-WRKCYGNDLKHCKGVFNDGVCNPECNNVDCL--FDGEDCHKS--SCKFHKC 1279
C+NGGTC+ + + C C +F G+ CQF NPCL C NGG C+ + +N + F C+C G++ C P + C N G C++ T CKC PG+TG C + C S+ C NGG C D+ IC C F+G+ C KQ + + SP C+N G+C + ++ CN Y G C+ ++ C + H G + EC+ CL F G++C ++ C H+C
Sbjct: 28 CQNGGTCVPTPDGRGGECKCPEKFWGSACQFSNPCLPNPCWNGGVCQPVIRDNKVDFVCQCHLGYMDPRCLT-----PTDNPCRSSPCGNGGTCELTSVRTYKCKCPPGWTGKNCQQADP------CASNPCANGGQCSPFDSHY-ICTCTPFFSGETC-----------------------KQDVNECALSPFPCNN-------GGVCVNEVGSYRCNCPTEYTGKHCETLYQPCSPSPCLHGGTCVQKGETSYECS---CLPGFSGQNCEENIDDCPDHRC 265 HSP 8 Score: 71.2478 bits (173), Expect = 6.946e-12 Identity = 63/206 (30.58%), Postives = 82/206 (39.81%), Query Frame = 2
Query: 332 SKLCSNRPCVNGKCVEAF----DPEFRCSCWHGWKGETC-EENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
S C PC NG + +F C C G+ C N C +PC NGGTC + C C + G CQ +PC + C NGG C ++ + C C F GE C C + P CNN G C + + C C YTG C+ + C C +GG C S C C F+G+NC
Sbjct: 59 SNPCLPNPCWNGGVCQPVIRDNKVDFVCQCHLGYMDPRCLTPTDNPCRSSPCGNGGTCELTSVRTYKCKCPPGWTGKNCQQADPCASNPCANGGQCSPFDS-HYICTCTPFFSGETCKQDVNECALSPFP----CNNGGVC-VNEVGSYRCNCPTEYTGKHCETLYQP-----CSPSPCLHGGTCVQKGETSYECSCLPGFSGQNC 253 HSP 9 Score: 69.707 bits (169), Expect = 2.224e-11 Identity = 52/164 (31.71%), Postives = 77/164 (46.95%), Query Frame = 2
Query: 353 PCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGC 838
PC NG CV +RC+C + G+ CE C +PC +GGTC+ K + + C+C F G C+ + C + C NGGTC N + C+C+ + G+FC C ++P C N G C + C C G+TG+ C K + + C
Sbjct: 187 PCNNGGVCVNEVG-SYRCNCPTEYTGKHCETLYQPCSPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVN-TYNCQCKPEWTGQFCTEDVNECDLMPNS----CQNGGTC-LNTQGGYNCVCVNGWTGEDCSKNIDDCADAAC 343
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: notch1b (neurogenic locus notch homolog protein 1-like [Source:NCBI gene;Acc:103025197]) HSP 1 Score: 202.986 bits (515), Expect = 4.085e-52 Identity = 244/1010 (24.16%), Postives = 404/1010 (40.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS---------------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP---------------LKETRKEALINIKIPKTFNE--------------KQLIIKKTKSPSLCD-NLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTS----RSNSF------FSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFL-------------QKLSSSLRMVVTVFNVTEINFNFATAL--LIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPK--LPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDS----------------LESTDGIHPI------DAGL--GDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C PC NG + + C C G+ G C +N+C+ PC+NGGTCID N+ + C C ++G C+ + N CL+ C+ GT C L N ++C+CR G+ G+ C V K + C N G C + N CKC PG+TG C+ + C S C NGG C V + +P C C FTG C P + + + + P FN + I + + C+ C+A N CD CN+ C++DGGDC DPW+ C +D C FN+G C+ +C++ CL+DG DC +S + + C + Y + CD+ CN+ +C +DG DC + R+ E L ++ L EL VL T + + E + SL V+ + + + ++ L ++ QC +CF S ++ FL A GN L+LP+ +A + + + P+Y ++ + LL F + R + G+L W P ++ S G L LK+ N+ +GE +P D R + +Q + +++++ + ++ A ++ S + + DG P+ GL G+ ++ D YQ ++L + GE+ +H+AAR + + A + + D GRTPL +++AADA + Q+LI + +++ + TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL +F I MD P+ IA+E+ ++I L+ E
Sbjct: 1148 CIPNPCQNGATCTDYLGGYSCECVPGYHGVNCSSEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRCVDRVGGYHCVCPPGYVGERCEGDVNECLSNPCDPRGTHSCIQLTNN-YRCECRTGYTGQRCDT------VFDGCKGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAQ-----ACGSLQCKNGGTC-VSGHKNPRCLCSPSFTGPECQYPSDGPCLSNPCYNGGTCEPSTESPYFHCVCPADFNGLLCHILDYGFTGGFGRDITPPPEVEASCEIPECEAKKGNKECDAACNSHECDWDGGDCSLNFRDPWQNC--SDALQCWRYFNNGKCDEQCHSAGCLYDGFDCQRSGGECNPLYDQYCKDHYADGHCDQGCNNAECEWDGLDCADNVPEKRATGLLVLVVHLPPEQLRN-NSSGFLRELSRVLHTNIVFRQDTQGELMIYPYYGSPHELRKHNKKRSLDSWSDVYGSGRRDQDQTQVVGSVVYLEIDNRQCYQQSAECFQSATDVAAFLGALASSGN-LNLPYVMAVTSESEVPPT-TELYPLYVVLASVALLAFVAVGMVASRKRRREHGQL---------WFPDGFKTSEPSKKKRREPVGEDSVGLKPLKNSDISLMDDNQNEWGEEEP-VDTKRFRYEEQA---MLDLDDQQDHRQWTQQHLDAADLRIPSVAPTPPQGEIENDCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDASANVINDFIYQGANLH---NQTDRTGETALHLAARYARSDAAKRLLEASADANIQ--DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDARMH-------------------DGTTPLILAARLAVEGMVEELINCHADVNAIDDFGKSALHWAAAVNNVDAAVVLLKNGANK---DMQNNKEETPLFLAAREGSYETAKVLLEHFANREITDHMD---RLPRDIAQERMHHDIVRLMDE 2095 HSP 2 Score: 108.612 bits (270), Expect = 3.009e-23 Identity = 120/434 (27.65%), Postives = 171/434 (39.40%), Query Frame = 2
Query: 332 SKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVI--PKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDK-----------------------------------KKELPVEIGCKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGIC----DQQCNTFACNYDGGDCDP--------------------------WRKCYGNDLK------------HCKGVFNDGVCNPECNNVDCLFDGEDCH-------KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTS 1363
++LC N +G C++A + + C C G+ G CEE V++CI NPC+NG TC D ++C C + G C E N CL+ C+NGGTC L N ++C C G G C + C P K C N G C + C C PGY G+RC+ ++ V GCK C NGG C V N +P IC+C FTG C E +A +++ + K+P LC SF C D C + C Y+GG C+P + +G D+ C+ + C+ CN+ +C +DG DC ++ +C + N CDE+C+S C +DG DC S
Sbjct: 1112 ARLCRN----SGLCLDAGNTHY-CQCQAGYTGSYCEEQVDECIPNPCQNGATCTDYLGG-YSCECVPGYHGVNCSSEINECLSQPCQNGGTCIDLVN-TYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRC-VDRVGGYHCVCPPGYVGERCEGDVNECLSNPCDPRGTHSCIQLTNNYRCECRTGYTGQRCDTVFDGCKGKPCRNGGTCAVASN-TPHGFICKCPPGFTGSTC-----EYDAQACGSLQC----KNGGTCVSGHKNPRC---LCSPSFTGPECQYPSDGPCLSNPC-YNGGTCEPSTESPYFHCVCPADFNGLLCHILDYGFTGGFGRDITPPPEVEASCEIPECEAKKGNKECDAACNSHECDWDGGDCSLNFRDPWQNCSDALQCWRYFNNGKCDEQCHSAGCLYDGFDCQRS 1523 HSP 3 Score: 97.4413 bits (241), Expect = 7.891e-20 Identity = 71/218 (32.57%), Postives = 105/218 (48.17%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C+ C NG CV+ + F C C G+ G C+ ++N+C PC NGGTC D + + C C + G CQ N C C+NGGTC + C+C+ G+ G +C V +++C V K++ LC N G C + T +C+C GYTG C+++ + C + C NG C G CEC + G NC+ + E + N
Sbjct: 986 CTESSCFNGGTCVDGIN-TFSCLCLAGFTGSYCQHDINECDSKPCMNGGTCQDSYGT-YKCTCPHGYRGFNCQELVNWCKPSPCKNGGTCRQ-SGTTYTCQCQTGWTGLYCDVPSVSCEVAAKQQGVEVARLCRNSGLC-LDAGNTHYCQCQAGYTGSYCEEQVDE-----CIPNPCQNGATCTDYLGGY-SCECVPGYHGVNCSSEINECLSQPCQN 1193 HSP 4 Score: 95.9005 bits (237), Expect = 2.306e-19 Identity = 76/252 (30.16%), Postives = 106/252 (42.06%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC G C ++ F C C G+ G CE N+N+C+ +PC+NGGTC D++N+ + C C + G LC + C C NGGTC NG F C+CR G+ C Q C P I HG C+ N C CD G++G+ CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 569 CLSNPCHYGLCKDSL-AGFTCHCRAGYTGRLCEANINECLSHPCQNGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQSNPCDFGKCIDKINGYECACEPGYTGKLCSINIDECAINPCHNGGTCIDGVNG-FMCQCRDGYHDPTCQSQLNECLSNPCI----------HGHCEDRVN-GYNCICDSGWSGNNCDINNNE-----CESNPCMNGGTCKDMTSGY-VCSCRAGFSGPNCQTNINECASNPCLN 801 HSP 5 Score: 90.1225 bits (222), Expect = 1.505e-17 Identity = 74/227 (32.60%), Postives = 104/227 (45.81%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC--LNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEK 1006
CS PC++G CV+ + + CSC G+ G+ CEEN++DC + C NGGTC+D N+ + C C ++ G C + N C + +C+NGGTC + + G + C C G+ GE C+ I CN C + FC+C PG TG C + C S+ C G C NG IC C + G C + E A K N K
Sbjct: 221 CSPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNT-YNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGG-YNCVCVNGWTGEDCSKN------IDDCADAACNVGATCHDRV-ASFFCECPPGRTGLLCH------LNDACISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECSLGANPCEHAGKCLNTK 432 HSP 6 Score: 88.1965 bits (217), Expect = 4.703e-17 Identity = 81/278 (29.14%), Postives = 116/278 (41.73%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPLKETRKEALIN------------IKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFAC 1111
+++ C + PC+NG + + CSC G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ +PC C+N G C ES + F C C G+ G+ C + C P + C N + C C GYTG C+ + CK + C NGG CK +G + C C F G C + E N P F+ I + +P ++ C F G C NTF+C
Sbjct: 751 INNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCLLPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNPCRNGATCQNS-------IGSYRCSCKSGYTGRNCETDID-----DCKPNPCSNGGFCK---DGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNGANCTDCVNSYTCTCPPGFSG---INCENNTPDCTESSC---FNGGTCVDGINTFSC 1006 HSP 7 Score: 85.8853 bits (211), Expect = 2.814e-16 Identity = 82/283 (28.98%), Postives = 122/283 (43.11%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQF-TCNCTSQFIGNLCQFENPCLNVNCENGGTCESL--ENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACN----YDGGDCDP-WRKCYGNDLKHCKGVFNDGVCNPECNNVDCL--FDGEDCHKS--SCKFHKC 1279
C+NGGTC+ + + C C +F G+ CQF NPCL C NGG C+ + +N + F C+C G++ C P + C N G C++ T CKC PG+TG C + C S+ C NGG C D+ IC C F+G+ C KQ + + SP C+N G+C + ++ CN Y G C+ ++ C + H G + EC+ CL F G++C ++ C H+C
Sbjct: 28 CQNGGTCVPTPDGRGGECKCPEKFWGSACQFSNPCLPNPCWNGGVCQPVIRDNKVDFVCQCHLGYMDPRCLT-----PTDNPCRSSPCGNGGTCELTSVRTYKCKCPPGWTGKNCQQADP------CASNPCANGGQCSPFDSHY-ICTCTPFFSGETC-----------------------KQDVNECALSPFPCNN-------GGVCVNEVGSYRCNCPTEYTGKHCETLYQPCSPSPCLHGGTCVQKGETSYECS---CLPGFSGQNCEENIDDCPDHRC 265 HSP 8 Score: 71.2478 bits (173), Expect = 6.946e-12 Identity = 63/206 (30.58%), Postives = 82/206 (39.81%), Query Frame = 2
Query: 332 SKLCSNRPCVNGKCVEAF----DPEFRCSCWHGWKGETC-EENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
S C PC NG + +F C C G+ C N C +PC NGGTC + C C + G CQ +PC + C NGG C ++ + C C F GE C C + P CNN G C + + C C YTG C+ + C C +GG C S C C F+G+NC
Sbjct: 59 SNPCLPNPCWNGGVCQPVIRDNKVDFVCQCHLGYMDPRCLTPTDNPCRSSPCGNGGTCELTSVRTYKCKCPPGWTGKNCQQADPCASNPCANGGQCSPFDS-HYICTCTPFFSGETCKQDVNECALSPFP----CNNGGVC-VNEVGSYRCNCPTEYTGKHCETLYQP-----CSPSPCLHGGTCVQKGETSYECSCLPGFSGQNC 253 HSP 9 Score: 69.707 bits (169), Expect = 2.224e-11 Identity = 52/164 (31.71%), Postives = 77/164 (46.95%), Query Frame = 2
Query: 353 PCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGC 838
PC NG CV +RC+C + G+ CE C +PC +GGTC+ K + + C+C F G C+ + C + C NGGTC N + C+C+ + G+FC C ++P C N G C + C C G+TG+ C K + + C
Sbjct: 187 PCNNGGVCVNEVG-SYRCNCPTEYTGKHCETLYQPCSPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVN-TYNCQCKPEWTGQFCTEDVNECDLMPNS----CQNGGTC-LNTQGGYNCVCVNGWTGEDCSKNIDDCADAAC 343
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: notch1b (neurogenic locus notch homolog protein 1-like [Source:NCBI gene;Acc:103025197]) HSP 1 Score: 202.601 bits (514), Expect = 4.936e-52 Identity = 244/1010 (24.16%), Postives = 404/1010 (40.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS---------------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP---------------LKETRKEALINIKIPKTFNE--------------KQLIIKKTKSPSLCD-NLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTS----RSNSF------FSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFL-------------QKLSSSLRMVVTVFNVTEINFNFATAL--LIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPK--LPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDS----------------LESTDGIHPI------DAGL--GDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C PC NG + + C C G+ G C +N+C+ PC+NGGTCID N+ + C C ++G C+ + N CL+ C+ GT C L N ++C+CR G+ G+ C V K + C N G C + N CKC PG+TG C+ + C S C NGG C V + +P C C FTG C P + + + + P FN + I + + C+ C+A N CD CN+ C++DGGDC DPW+ C +D C FN+G C+ +C++ CL+DG DC +S + + C + Y + CD+ CN+ +C +DG DC + R+ E L ++ L EL VL T + + E + SL V+ + + + ++ L ++ QC +CF S ++ FL A GN L+LP+ +A + + + P+Y ++ + LL F + R + G+L W P ++ S G L LK+ N+ +GE +P D R + +Q + +++++ + ++ A ++ S + + DG P+ GL G+ ++ D YQ ++L + GE+ +H+AAR + + A + + D GRTPL +++AADA + Q+LI + +++ + TT LI A +L + M+ L++ + VN +D G+S +HW+A NN L + D+++N++++PLFLAA EG+ ++ K LL +F I MD P+ IA+E+ ++I L+ E
Sbjct: 1122 CIPNPCQNGATCTDYLGGYSCECVPGYHGVNCSSEINECLSQPCQNGGTCIDLVNTYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRCVDRVGGYHCVCPPGYVGERCEGDVNECLSNPCDPRGTHSCIQLTNN-YRCECRTGYTGQRCDT------VFDGCKGKPCRNGGTCAVASNTPHGFICKCPPGFTGSTCEYDAQ-----ACGSLQCKNGGTC-VSGHKNPRCLCSPSFTGPECQYPSDGPCLSNPCYNGGTCEPSTESPYFHCVCPADFNGLLCHILDYGFTGGFGRDITPPPEVEASCEIPECEAKKGNKECDAACNSHECDWDGGDCSLNFRDPWQNC--SDALQCWRYFNNGKCDEQCHSAGCLYDGFDCQRSGGECNPLYDQYCKDHYADGHCDQGCNNAECEWDGLDCADNVPEKRATGLLVLVVHLPPEQLRN-NSSGFLRELSRVLHTNIVFRQDTQGELMIYPYYGSPHELRKHNKKRSLDSWSDVYGSGRRDQDQTQVVGSVVYLEIDNRQCYQQSAECFQSATDVAAFLGALASSGN-LNLPYVMAVTSESEVPPT-TELYPLYVVLASVALLAFVAVGMVASRKRRREHGQL---------WFPDGFKTSEPSKKKRREPVGEDSVGLKPLKNSDISLMDDNQNEWGEEEP-VDTKRFRYEEQA---MLDLDDQQDHRQWTQQHLDAADLRIPSVAPTPPQGEIENDCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDASANVINDFIYQGANLH---NQTDRTGETALHLAARYARSDAAKRLLEASADANIQ--DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDARMH-------------------DGTTPLILAARLAVEGMVEELINCHADVNAIDDFGKSALHWAAAVNNVDAAVVLLKNGANK---DMQNNKEETPLFLAAREGSYETAKVLLEHFANREITDHMD---RLPRDIAQERMHHDIVRLMDE 2069 HSP 2 Score: 108.227 bits (269), Expect = 3.722e-23 Identity = 120/434 (27.65%), Postives = 171/434 (39.40%), Query Frame = 2
Query: 332 SKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVI--PKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDK-----------------------------------KKELPVEIGCKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGIC----DQQCNTFACNYDGGDCDP--------------------------WRKCYGNDLK------------HCKGVFNDGVCNPECNNVDCLFDGEDCH-------KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTS 1363
++LC N +G C++A + + C C G+ G CEE V++CI NPC+NG TC D ++C C + G C E N CL+ C+NGGTC L N ++C C G G C + C P K C N G C + C C PGY G+RC+ ++ V GCK C NGG C V N +P IC+C FTG C E +A +++ + K+P LC SF C D C + C Y+GG C+P + +G D+ C+ + C+ CN+ +C +DG DC ++ +C + N CDE+C+S C +DG DC S
Sbjct: 1086 ARLCRN----SGLCLDAGNTHY-CQCQAGYTGSYCEEQVDECIPNPCQNGATCTDYLGG-YSCECVPGYHGVNCSSEINECLSQPCQNGGTCIDLVN-TYKCSCPRGTQGVHCEINLDDCTPFTDPVTKEPKCFNQGRC-VDRVGGYHCVCPPGYVGERCEGDVNECLSNPCDPRGTHSCIQLTNNYRCECRTGYTGQRCDTVFDGCKGKPCRNGGTCAVASN-TPHGFICKCPPGFTGSTC-----EYDAQACGSLQC----KNGGTCVSGHKNPRC---LCSPSFTGPECQYPSDGPCLSNPC-YNGGTCEPSTESPYFHCVCPADFNGLLCHILDYGFTGGFGRDITPPPEVEASCEIPECEAKKGNKECDAACNSHECDWDGGDCSLNFRDPWQNCSDALQCWRYFNNGKCDEQCHSAGCLYDGFDCQRS 1497 HSP 3 Score: 97.4413 bits (241), Expect = 8.680e-20 Identity = 71/218 (32.57%), Postives = 105/218 (48.17%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C+ C NG CV+ + F C C G+ G C+ ++N+C PC NGGTC D + + C C + G CQ N C C+NGGTC + C+C+ G+ G +C V +++C V K++ LC N G C + T +C+C GYTG C+++ + C + C NG C G CEC + G NC+ + E + N
Sbjct: 960 CTESSCFNGGTCVDGIN-TFSCLCLAGFTGSYCQHDINECDSKPCMNGGTCQDSYGT-YKCTCPHGYRGFNCQELVNWCKPSPCKNGGTCRQ-SGTTYTCQCQTGWTGLYCDVPSVSCEVAAKQQGVEVARLCRNSGLC-LDAGNTHYCQCQAGYTGSYCEEQVDE-----CIPNPCQNGATCTDYLGGY-SCECVPGYHGVNCSSEINECLSQPCQN 1167 HSP 4 Score: 95.5153 bits (236), Expect = 2.737e-19 Identity = 76/252 (30.16%), Postives = 106/252 (42.06%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNS------------------------------------QFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIAC---PVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC G C ++ F C C G+ G CE N+N+C+ +PC+NGGTC D++N+ + C C + G LC + C C NGGTC NG F C+CR G+ C Q C P I HG C+ N C CD G++G+ CD C+S+ C NGG CK + +G +C C+ F+G NC + E +N
Sbjct: 543 CLSNPCHYGLCKDSL-AGFTCHCRAGYTGRLCEANINECLSHPCQNGGTCQDRENAYLCVCPRGTSGVNCEINLDDCQSNPCDFGKCIDKINGYECACEPGYTGKLCSINIDECAINPCHNGGTCIDGVNG-FMCQCRDGYHDPTCQSQLNECLSNPCI----------HGHCEDRVN-GYNCICDSGWSGNNCDINNNE-----CESNPCMNGGTCKDMTSGY-VCSCRAGFSGPNCQTNINECASNPCLN 775 HSP 5 Score: 89.7373 bits (221), Expect = 1.685e-17 Identity = 74/227 (32.60%), Postives = 104/227 (45.81%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPC--LNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEK 1006
CS PC++G CV+ + + CSC G+ G+ CEEN++DC + C NGGTC+D N+ + C C ++ G C + N C + +C+NGGTC + + G + C C G+ GE C+ I CN C + FC+C PG TG C + C S+ C G C NG IC C + G C + E A K N K
Sbjct: 195 CSPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVNT-YNCQCKPEWTGQFCTEDVNECDLMPNSCQNGGTCLNTQGG-YNCVCVNGWTGEDCSKN------IDDCADAACNVGATCHDRV-ASFFCECPPGRTGLLCH------LNDACISNPCQKGSNCDTNPVNGKAICTCPLGYFGSACDQDVDECSLGANPCEHAGKCLNTK 406 HSP 6 Score: 88.1965 bits (217), Expect = 5.265e-17 Identity = 81/278 (29.14%), Postives = 116/278 (41.73%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPLKETRKEALIN------------IKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFAC 1111
+++ C + PC+NG + + CSC G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ +PC C+N G C ES + F C C G+ G+ C + C P + C N + C C GYTG C+ + CK + C NGG CK +G + C C F G C + E N P F+ I + +P ++ C F G C NTF+C
Sbjct: 725 INNNECESNPCMNGGTCKDMTSGYVCSCRAGFSGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCLLPYTGENCETLLDPCNPKPCKNNGVCKESEDYESFSCVCPEGWQGQTCEIDINECVKNPCRNGATCQNS-------IGSYRCSCKSGYTGRNCETDID-----DCKPNPCSNGGFCK---DGVDVFSCTCLPGFRGLRCEEDINECDSNPCKNGANCTDCVNSYTCTCPPGFSG---INCENNTPDCTESSC---FNGGTCVDGINTFSC 980 HSP 7 Score: 74.3294 bits (181), Expect = 9.533e-13 Identity = 75/264 (28.41%), Postives = 111/264 (42.05%), Query Frame = 2
Query: 524 CTSQFIGNLCQFENPCLNVNCENGGTCESL--ENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACN----YDGGDCDP-WRKCYGNDLKHCKGVFNDGVCNPECNNVDCL--FDGEDCHKS--SCKFHKC 1279
C +F G+ CQF NPCL C NGG C+ + +N + F C+C G++ C P + C N G C++ T CKC PG+TG C + C S+ C NGG C D+ IC C F+G+ C KQ + + SP C+N G+C + ++ CN Y G C+ ++ C + H G + EC+ CL F G++C ++ C H+C
Sbjct: 21 CPEKFWGSACQFSNPCLPNPCWNGGVCQPVIRDNKVDFVCQCHLGYMDPRCLT-----PTDNPCRSSPCGNGGTCELTSVRTYKCKCPPGWTGKNCQQADP------CASNPCANGGQCSPFDSHY-ICTCTPFFSGETC-----------------------KQDVNECALSPFPCNN-------GGVCVNEVGSYRCNCPTEYTGKHCETLYQPCSPSPCLHGGTCVQKGETSYECS---CLPGFSGQNCEENIDDCPDHRC 239 HSP 8 Score: 71.2478 bits (173), Expect = 8.052e-12 Identity = 63/206 (30.58%), Postives = 82/206 (39.81%), Query Frame = 2
Query: 332 SKLCSNRPCVNGKCVEAF----DPEFRCSCWHGWKGETC-EENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
S C PC NG + +F C C G+ C N C +PC NGGTC + C C + G CQ +PC + C NGG C ++ + C C F GE C C + P CNN G C + + C C YTG C+ + C C +GG C S C C F+G+NC
Sbjct: 33 SNPCLPNPCWNGGVCQPVIRDNKVDFVCQCHLGYMDPRCLTPTDNPCRSSPCGNGGTCELTSVRTYKCKCPPGWTGKNCQQADPCASNPCANGGQCSPFDS-HYICTCTPFFSGETCKQDVNECALSPFP----CNNGGVC-VNEVGSYRCNCPTEYTGKHCETLYQP-----CSPSPCLHGGTCVQKGETSYECSCLPGFSGQNC 227 HSP 9 Score: 69.3218 bits (168), Expect = 2.689e-11 Identity = 52/164 (31.71%), Postives = 77/164 (46.95%), Query Frame = 2
Query: 353 PCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGC 838
PC NG CV +RC+C + G+ CE C +PC +GGTC+ K + + C+C F G C+ + C + C NGGTC N + C+C+ + G+FC C ++P C N G C + C C G+TG+ C K + + C
Sbjct: 161 PCNNGGVCVNEVG-SYRCNCPTEYTGKHCETLYQPCSPSPCLHGGTCVQKGETSYECSCLPGFSGQNCEENIDDCPDHRCLNGGTCVDGVN-TYNCQCKPEWTGQFCTEDVNECDLMPNS----CQNGGTC-LNTQGGYNCVCVNGWTGEDCSKNIDDCADAAC 317
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:103042072]) HSP 1 Score: 162.155 bits (409), Expect = 1.414e-39 Identity = 144/567 (25.40%), Postives = 233/567 (41.09%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVN-------CENGGTCESLENGMFQCKCRYGFIGEFC-------------AVQNIACPVIPKKKRELC----------NNHGECDIYP-------------NMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC------TIPLKETRKEALI---------------NIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVV----------TVFNVTEINFNFATALL---------IKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIY 1762
C ++PC+NG + + C C G++G+ CE +N+C +PC+NGGTCID + C+C +G LC+ E+ C C+N GTC G ++C C G+ G+ C A ++ C +P +C N G C+ P + C C GYTG C++ + C+ C+NGG C V G+ C C+ F G C + K R + K + E +++ + + + D C +G+CD++CN+ AC +DGGDC +PW +C C VFN+ C+ CNN DCL+D DC + C + Y + CD+ CN+ +CG+DG DC +R+ +G+ L +V++ + + + FLQKLSS LR + + T + L+ + L ++ C CF + + + +L A + +L P+ L V I K Q +P++
Sbjct: 1103 CEDKPCLNGATCRGYVGGYTCDCMPGYEGQNCEREINECRSHPCQNGGTCIDLV-GHYICSCPPGTMGVLCEINEDDCATPTRPRGTPKCQNNGTCVDRVGG-YRCNCPPGYTGDRCEGDINECHSNPCNAANSLDCIQLPNDYLCVCKPGFTGRGCQNRFGVCESQPCKNGGACSGAGSSPLGYICTCQLGYTGTNCERS------MSCRELSCYNGGSCTVTSRGA-RCSCQQGFAGPQCQHRSNQSCSSKPCRNNGICIEEANFPFFSCQCMEGWKGKRCEQESRMLERPAPTCLIAD--CHGKANDGVCDKECNSMACRWDGGDCSLAANPWARCAD---PRCWRVFNNSQCDESCNNADCLYDNFDCKTKEKVCNPIYETYCMDHYADGRCDQGCNNEECGWDGLDC--ARTIPEDLADGV-----------LVIVVLLPPEELLRTGTAFLQKLSSILRTSLRFRLDQNGDAMIRPYTRRDGRPKRELMPQQEVIGSIVYLEIDNRLCSQDSNDCFPTADSAAEYLGA-LSAREMLRFPYPLKEVRGEKI---KDQVVPVW 1638 HSP 2 Score: 111.694 bits (278), Expect = 3.893e-24 Identity = 78/202 (38.61%), Postives = 103/202 (50.99%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPE-FRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
CS+ PCV+G C E DP+ +RC C GW G+ C+ + NDC+ NPC+N GTCID+ N FTC C F GN CQ N C + C N GTC F C C + G CA C P C+NH C P+ + C C PG+ G C+ +++ C S+ C N G C G +C C+G ++G NC
Sbjct: 675 CSSSPCVHGACRE--DPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAGTCIDQLNG-FTCKCRQGFRGNQCQVNINECASSPCLNQGTCVD-GVASFTCLCEAPYSGPTCAEVLTPCSPNP------CSNHAVCTHTPDYFGYQCNCQPGWQGHLCN------IDVNECASNPCKNRGTCTNTLGGY-VCSCRGGYSGPNC 859 HSP 3 Score: 98.2117 bits (243), Expect = 4.225e-20 Identity = 73/202 (36.14%), Postives = 100/202 (49.50%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C + PC N C++ EF C C G+ G CE ++++C NPC N G C D N+ FTC C + F G +CQ + + C + C+NG C NG ++C+C GF G C C P +HG C + + C C PGYTG RC+ + C S+ C NGG C L N IC+C+ +G NC I
Sbjct: 411 CLSMPCQNDATCLDRIG-EFTCICMPGYTGTHCEIDIDECESNPCVNDGICRDLVNA-FTCTCQTGFTGTMCQIDIDECASTPCQNGAKCIDRPNG-YECRCAEGFEGRLCESNIDNCQPDPC-------HHGTC-VDGIASYTCNCVPGYTGYRCENQLNE-----CHSNPCQNGGKCVDLVNKY-ICQCQHGTSGTNCEI 595 HSP 4 Score: 97.4413 bits (241), Expect = 7.629e-20 Identity = 77/279 (27.60%), Postives = 111/279 (39.78%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL------CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVN----------------------------------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+N F CL + C + PC NG + + C+C G+ G CE N DC ++ C NGGTC+DK N F+C C F G CQ+E PCLN C+NGG C + C C G+ G +C + ++C + ++ ELC+ G C + T +CKC YTG C+ + + C+ C NG C+ G C+C + G+NC + E R N
Sbjct: 881 INTFYCTCLPGFTGPRCAIEVDECQSAPCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKING-FSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQDGLESFRCSCPKGYTGSRCQVRVDWCRHSNPCQNGGRCRPKDG---SCDCVGGWSGRYCDIPGVSCEMAAMQRGLQTDELCHRGGHC-VNTGNTHYCKCPNDYTGSYCESQVDH-----CEDKPCLNGATCRGYVGGY-TCDCMPGYEGQNCEREINECRSHPCQN 1148 HSP 5 Score: 97.0561 bits (240), Expect = 1.097e-19 Identity = 76/249 (30.52%), Postives = 103/249 (41.37%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGM-------------------------------------FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEAL 970
C++ PC N G C + CSC G+ G CE ++NDC+ NPC +GG+C D N+ F C C F G C E + C + C+NGGTC N F C CR GF GE C + C P +C + E + C C GYTG RC ++ V+ S+ C NGG C+ D C+C G ++G+ C IP A+
Sbjct: 828 CASNPCKNRGTCTNTLG-GYVCSCRGGYSGPNCETDINDCLPNPCMSGGSCTDGINT-FYCTCLPGFTGPRCAIEVDECQSAPCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQDGLE-------SFRCSCPKGYTGSRC----QVRVDWCRHSNPCQNGGRCRPKDGS---CDCVGGWSGRYCDIPGVSCEMAAM 1060 HSP 6 Score: 90.1225 bits (222), Expect = 1.360e-17 Identity = 69/235 (29.36%), Postives = 119/235 (50.64%), Query Frame = 2
Query: 2243 DEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D YQ +SL G + GE+ +H+AAR + ++A + ++ D GRTPL +++A+DA + Q+LI + +++ +TALI A +L + M+ L+ + VN +D G+S +HW+A NN +E + D++D ++++PLFLAA EG+ ++VK LLA+F I MD P+ IA+++ ++I L+ E
Sbjct: 1822 DLIYQGASL---GAQTDRTGETALHLAARYARADAAKRLLDAG--ADANAQDNTGRTPLHAAVASDA-QGVFQILIRTRATDLDAR-------------------MYDGSTALILAARLAVEGMVEELITCHADVNAVDELGKSALHWAAAVNN---VEATVALLKNGANKDMQDLKEETPLFLAAREGSCEAVKILLAHFANREITDHMDRL---PRDIAQDRMHHDIVQLLDE 2025 HSP 7 Score: 87.4261 bits (215), Expect = 1.005e-16 Identity = 67/214 (31.31%), Postives = 95/214 (44.39%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQ-NPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C+ PC NG ++ + CSC G++G+ C ++++C + C NGG CI+ S F C C S + G C+ PC C NGGTC + ++C C GF G C V CP C N G C N T C+C P +TG C + E + + C NGG C G C C +TG +C+ + + N
Sbjct: 100 CATSPCANGARCTNWNNHYNCSCPPGFQGKNCRNDIDECRKPGKCLNGGICINTHGS-FRCECVSGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFGGTNCEVNVDDCP------GHKCMNGGTCVDGVN-TYNCQCPPEWTGQYCAEDVN---ECLMQPNACHNGGTCFNTIGGH-TCVCVNGWTGDDCSENIDDCATAVCFN 301 HSP 8 Score: 80.4925 bits (197), Expect = 1.143e-14 Identity = 57/173 (32.95%), Postives = 82/173 (47.40%), Query Frame = 2
Query: 467 PCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCES-LENGM--FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
PC+NGG C+D + C C +IG LCQ +PC C NG C+S + NG+ F C C+ GF G+ C++ + AC P C N N C C PG+ G C ++ K C NGG+C + +GS CEC ++G+ C +P + +N
Sbjct: 30 PCENGGMCLDSR-----CMCRPGYIGPLCQHLDPCHRSPCLNGAACKSQVANGVPQFTCVCQRGFRGQNCSLID-ACATSPCANGARCTNW-------NNHYNCSCPPGFQGKNCRND----IDECRKPGKCLNGGIC-INTHGSFRCECVSGYSGRTCEVPTQPCAPSQCLN 184 HSP 9 Score: 78.5666 bits (192), Expect = 4.481e-14 Identity = 66/213 (30.99%), Postives = 94/213 (44.13%), Query Frame = 2
Query: 350 RPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTC---IDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
RPC NG C+++ RC C G+ G C+ +++ C ++PC NG C + QFTC C F G C + C C NG C + N + C C GF G+ C C +K C N G C I + + C+C GY+G C E+P + C C NGG C + + C C F G NC + + + +N
Sbjct: 29 RPCENGGMCLDS-----RCMCRPGYIGPLCQ-HLDPCHRSPCLNGAACKSQVANGVPQFTCVCQRGFRGQNCSLIDACATSPCANGARCTNWNN-HYNCSCPPGFQGKNCRNDIDEC-----RKPGKCLNGGIC-INTHGSFRCECVSGYSGRTC----EVPTQP-CAPSQCLNGGTCHQTGDHTYECACLPGFGGTNCEVNVDDCPGHKCMN 223 HSP 10 Score: 78.1814 bits (191), Expect = 5.723e-14 Identity = 66/210 (31.43%), Postives = 96/210 (45.71%), Query Frame = 2
Query: 341 CSNRPCVNGKC----VEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVN-CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C PC+NG V P+F C C G++G+ C ++ C +PC NG C + N+ + C+C F G C+ + + C C NGG C + +G F+C+C G+ G C V P P + C N G C + T C C PG+ G C+ + C C NGG C V + C+C E+TG+ C + E
Sbjct: 59 CHRSPCLNGAACKSQVANGVPQFTCVCQRGFRGQNCSL-IDACATSPCANGARCTN-WNNHYNCSCPPGFQGKNCRNDIDECRKPGKCLNGGICINT-HGSFRCECVSGYSGRTCEVPTQ--PCAPSQ----CLNGGTCHQTGDHTYECACLPGFGGTNCEVNVD-----DCPGHKCMNGGTC-VDGVNTYNCQCPPEWTGQYCAEDVNE 253 HSP 11 Score: 74.7146 bits (182), Expect = 5.919e-13 Identity = 63/221 (28.51%), Postives = 93/221 (42.08%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKN------------------------------------SQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNG 889
C + PCVN F C+C G+ G C+ ++++C PC+NG CID+ N + +TCNC + G C+ + N C + C+NGG C L N + C+C++G G C + C P + +G C N C C PG+TG +C+ VE+ C S+ C NGG C +NG
Sbjct: 449 CESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNCQPDPCHHGTCVDGIASYTCNCVPGYTGYRCENQLNECHSNPCQNGGKCVDLVN-KYICQCQHGTSGTNCEINYDDCASNPCE-------YGMCKDGINR-YDCVCKPGFTGPQCN------VELDECSSNPCRNGGTCVDDENG 654 HSP 12 Score: 74.3294 bits (181), Expect = 9.736e-13 Identity = 57/174 (32.76%), Postives = 76/174 (43.68%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC 871
C+NG FRC C G+ G TCE C + C NGGTC + + C C F G C+ + C C NGGTC N + C+C + G++CA C + P C+N G C + T C C G+TGD C + + C + CFNG C
Sbjct: 144 CLNGGICINTHGSFRCECVSGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFGGTNCEVNVDDCPGHKCMNGGTCVDGVN-TYNCQCPPEWTGQYCAEDVNECLMQPNA----CHNGGTCFNTIGGHT--CVCVNGWTGDDCSENID-----DCATAVCFNGATC 305
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:103042072]) HSP 1 Score: 159.073 bits (401), Expect = 1.098e-38 Identity = 143/558 (25.63%), Postives = 232/558 (41.58%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVN-------CENGGTCESLENGMFQCKCRYGFIGEFC-------------AVQNIACPVIPKKKRELC----------NNHGECDIYPNMTLFCK----CDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC------TIPLKETRKEALI---------------NIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVV----------TVFNVTEINFNFATALL---------IKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIY 1762
C ++PC+NG + + C C G++G+ CE +N+C +PC+NGGTCID + C+C +G LC+ E+ C C+N GTC G ++C C G+ G+ C A ++ C +P +C N G C+ P CK C GYTG C++ + C+ C+NGG C V G+ C C+ F G C + K R + K + E +++ + + + D C +G+CD++CN+ AC +DGGDC +PW +C C VFN+ C+ CNN DCL+D DC + C + Y + CD+ CN+ +CG+DG DC +R+ +G+ L +V++ + + + FLQKLSS LR + + T + L+ + L ++ C CF + + + +L A + +L P+ L V + Q +P++
Sbjct: 1006 CEDKPCLNGATCRGYVGGYTCDCMPGYEGQNCEREINECRSHPCQNGGTCIDLV-GHYICSCPPGTMGVLCEINEDDCATPTRPRGTPKCQNNGTCVDRVGG-YRCNCPPGYTGDRCEGDINECHSNPCNAANSLDCIQLPNDYLCVCKPGFTGRGCQNRFGVCESQP-----CKNGGACSGGYTGTNCERS------MSCRELSCYNGGSCTVTSRGA-RCSCQQGFAGPQCQHRSNQSCSSKPCRNNGICIEEANFPFFSCQCMEGWKGKRCEQESRMLERPAPTCLIAD--CHGKANDGVCDKECNSMACRWDGGDCSLAANPWARCAD---PRCWRVFNNSQCDESCNNADCLYDNFDCKTKEKVCNPIYETYCMDHYADGRCDQGCNNEECGWDGLDC--ARTIPEDLADGV-----------LVIVVLLPPEELLRTGTAFLQKLSSILRTSLRFRLDQNGDAMIRPYTRRDGRPKRELMPQQEVIGSIVYLEIDNRLCSQDSNDCFPTADSAAEYLGA-LSAREMLRFPYPLKEVRGECLHL--DQVVPVW 1528 HSP 2 Score: 104.375 bits (259), Expect = 5.549e-22 Identity = 85/249 (34.14%), Postives = 111/249 (44.58%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPE-FRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGN---LCQFENPCLNVNCENGGTCESLENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNN----------------HGECDI---YPNM------------TLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
CS+ PCV+G C E DP+ +RC C GW G+ C+ + NDC+ NPC+N GTCID+ N FTC C F G + PC C N C + +QC C+ G+ G C + C P K R C N + E DI PN T +C C PG+TG RC +E+ C+S C NGG C N S C CK FTG +C + + + N
Sbjct: 616 CSSSPCVHGACRE--DPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAGTCIDQLNG-FTCKCRQGFRGGGPTCAEVLTPCSPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNIDVNECASNPCKNRGTCTNTLGGYVCSCRGGYSGPNCETDINDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRC------AIEVDECQSAPCKNGGTCTDYVN-SYTCTCKPGFTGLHCETNAMDCTESSCFN 854 HSP 3 Score: 98.2117 bits (243), Expect = 4.883e-20 Identity = 77/277 (27.80%), Postives = 111/277 (40.07%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL------CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLNVN----------------------------------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKR--ELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+N F CL + C + PC NG + + C+C G+ G CE N DC ++ C NGGTC+DK N F+C C F G CQ+E PCLN C+NGG C + C C G+ G +C + ++C + ++ ELC+ G C + T +CKC YTG C+ + + C+ C NG C+ G C+C + G+NC + E R N
Sbjct: 786 INTFYCTCLPGFTGPRCAIEVDECQSAPCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKING-FSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQDGLESFRCSCPKGYTGSRCQVRVDWCRHSNPCQNGGRCRPKDG---SCDCVGGWSGRYCDIPGVSCEMAAMQRGLYELCHRGGHC-VNTGNTHYCKCPNDYTGSYCESQVDH-----CEDKPCLNGATCRGYVGGY-TCDCMPGYEGQNCEREINECRSHPCQN 1051 HSP 4 Score: 97.8265 bits (242), Expect = 5.314e-20 Identity = 73/202 (36.14%), Postives = 100/202 (49.50%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C + PC N C++ EF C C G+ G CE ++++C NPC N G C D N+ FTC C + F G +CQ + + C + C+NG C NG ++C+C GF G C C P +HG C + + C C PGYTG RC+ + C S+ C NGG C L N IC+C+ +G NC I
Sbjct: 352 CLSMPCQNDATCLDRIG-EFTCICMPGYTGTHCEIDIDECESNPCVNDGICRDLVNA-FTCTCQTGFTGTMCQIDIDECASTPCQNGAKCIDRPNG-YECRCAEGFEGRLCESNIDNCQPDPC-------HHGTC-VDGIASYTCNCVPGYTGYRCENQLNE-----CHSNPCQNGGKCVDLVNKY-ICQCQHGTSGTNCEI 536 HSP 5 Score: 90.1225 bits (222), Expect = 1.330e-17 Identity = 69/235 (29.36%), Postives = 119/235 (50.64%), Query Frame = 2
Query: 2243 DEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
D YQ +SL G + GE+ +H+AAR + ++A + ++ D GRTPL +++A+DA + Q+LI + +++ +TALI A +L + M+ L+ + VN +D G+S +HW+A NN +E + D++D ++++PLFLAA EG+ ++VK LLA+F I MD P+ IA+++ ++I L+ E
Sbjct: 1712 DLIYQGASL---GAQTDRTGETALHLAARYARADAAKRLLDA--GADANAQDNTGRTPLHAAVASDA-QGVFQILIRTRATDLDAR-------------------MYDGSTALILAARLAVEGMVEELITCHADVNAVDELGKSALHWAAAVNN---VEATVALLKNGANKDMQDLKEETPLFLAAREGSCEAVKILLAHFANREITDHMDRL---PRDIAQDRMHHDIVQLLDE 1915 HSP 6 Score: 87.0409 bits (214), Expect = 1.278e-16 Identity = 67/214 (31.31%), Postives = 95/214 (44.39%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQ-NPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C+ PC NG ++ + CSC G++G+ C ++++C + C NGG CI+ S F C C S + G C+ PC C NGGTC + ++C C GF G C V CP C N G C N T C+C P +TG C + E + + C NGG C G C C +TG +C+ + + N
Sbjct: 41 CATSPCANGARCTNWNNHYNCSCPPGFQGKNCRNDIDECRKPGKCLNGGICINTHGS-FRCECVSGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFGGTNCEVNVDDCP------GHKCMNGGTCVDGVN-TYNCQCPPEWTGQYCAEDVN---ECLMQPNACHNGGTCFNTIGGH-TCVCVNGWTGDDCSENIDDCATAVCFN 242 HSP 7 Score: 76.2554 bits (186), Expect = 2.219e-13 Identity = 65/206 (31.55%), Postives = 95/206 (46.12%), Query Frame = 2
Query: 353 PCVNGKC----VEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVN-CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
PC+NG V P+F C C G++G+ C ++ C +PC NG C + N+ + C+C F G C+ + + C C NGG C + +G F+C+C G+ G C V P P + C N G C + T C C PG+ G C+ + C C NGG C V + C+C E+TG+ C + E
Sbjct: 4 PCLNGAACKSQVANGVPQFTCVCQRGFRGQNCSL-IDACATSPCANGARCTN-WNNHYNCSCPPGFQGKNCRNDIDECRKPGKCLNGGICINT-HGSFRCECVSGYSGRTCEVPTQ--PCAPSQ----CLNGGTCHQTGDHTYECACLPGFGGTNCEVNVD-----DCPGHKCMNGGTC-VDGVNTYNCQCPPEWTGQYCAEDVNE 194 HSP 8 Score: 74.7146 bits (182), Expect = 6.931e-13 Identity = 63/221 (28.51%), Postives = 93/221 (42.08%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKN------------------------------------SQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNG 889
C + PCVN F C+C G+ G C+ ++++C PC+NG CID+ N + +TCNC + G C+ + N C + C+NGG C L N + C+C++G G C + C P + +G C N C C PG+TG +C+ VE+ C S+ C NGG C +NG
Sbjct: 390 CESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNCQPDPCHHGTCVDGIASYTCNCVPGYTGYRCENQLNECHSNPCQNGGKCVDLVN-KYICQCQHGTSGTNCEINYDDCASNPCE-------YGMCKDGINR-YDCVCKPGFTGPQCN------VELDECSSNPCRNGGTCVDDENG 595 HSP 9 Score: 73.9442 bits (180), Expect = 1.189e-12 Identity = 57/174 (32.76%), Postives = 76/174 (43.68%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVC 871
C+NG FRC C G+ G TCE C + C NGGTC + + C C F G C+ + C C NGGTC N + C+C + G++CA C + P C+N G C + T C C G+TGD C + + C + CFNG C
Sbjct: 85 CLNGGICINTHGSFRCECVSGYSGRTCEVPTQPCAPSQCLNGGTCHQTGDHTYECACLPGFGGTNCEVNVDDCPGHKCMNGGTCVDGVN-TYNCQCPPEWTGQYCAEDVNECLMQPNA----CHNGGTCFNTIGGHT--CVCVNGWTGDDCSENID-----DCATAVCFNGATC 246 HSP 10 Score: 65.0846 bits (157), Expect = 5.756e-10 Identity = 53/175 (30.29%), Postives = 73/175 (41.71%), Query Frame = 2
Query: 461 QNPCKNGGTC---IDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
++PC NG C + QFTC C F G C + C C NG C + N + C C GF G+ C C +K C N G C I + + C+C GY+G C E+P + C C NGG C + + C C F G NC + + + +N
Sbjct: 2 RSPCLNGAACKSQVANGVPQFTCVCQRGFRGQNCSLIDACATSPCANGARCTNWNN-HYNCSCPPGFQGKNCRNDIDEC-----RKPGKCLNGGIC-INTHGSFRCECVSGYSGRTC----EVPTQP-CAPSQCLNGGTCHQTGDHTYECACLPGFGGTNCEVNVDDCPGHKCMN 164
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002014.1 (pep scaffold:Pmarinus_7.0:GL482490:2146:12219:-1 gene:ENSPMAG00000001825.1 transcript:ENSPMAT00000002014.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 95.9005 bits (237), Expect = 1.552e-22 Identity = 72/210 (34.29%), Postives = 101/210 (48.10%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRK 961
CS PC NG +C++ + C C G+ G+ CE ++++C +PC+NGG C++ S FTC+C + + G LC + + C + C+NGG C + G F C C G+ G C C P C N G C + F C+C PG+TG RC+ C S C NGG C+ + CEC FTG C L K
Sbjct: 15 CSPNPCQNGGRCIDGA-ASYTCDCAQGFTGKRCETDIDECTSDPCQNGGQCVNGAGS-FTCSCLAGYTGTLCDSDIDECTSDPCQNGGQCVNGA-GSFTCSCLAGYTGTLCDSDVNECASSP------CLNGGRC--RDGVAAFTCECAPGFTGTRCETDVNE-----CASSPCLNGGRCRD-GVAAFTCECAPGFTGTRCETVLNPCTK 207 HSP 2 Score: 78.9518 bits (193), Expect = 1.219e-16 Identity = 61/179 (34.08%), Postives = 81/179 (45.25%), Query Frame = 2
Query: 443 NVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+V++C NPC+NGG CID S +TC+C F G C+ + + C + C+NGG C + G F C C G+ G C C P C N G+C + + C C GYTG CD C S C NGG C+ + CEC FTG C + E +N
Sbjct: 11 DVDECSPNPCQNGGRCIDGAAS-YTCDCAQGFTGKRCETDIDECTSDPCQNGGQCVNGA-GSFTCSCLAGYTGTLCDSDIDECTSDP------CQNGGQC-VNGAGSFTCSCLAGYTGTLCDSDVNE-----CASSPCLNGGRCRD-GVAAFTCECAPGFTGTRCETDVNECASSPCLN 174
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Match: JAG1 (jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188]) HSP 1 Score: 98.5969 bits (244), Expect = 5.149e-21 Identity = 82/243 (33.74%), Postives = 112/243 (46.09%), Query Frame = 2
Query: 257 ELIMIFAKGFPMNVFILGCLLVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVN-CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
++I P N G + V+S +C NG+C+ F C C G++G C ENVNDC + C NGGTC+D NS F C C + G C+ + + C N N C NGGTC L N F C+C+ G+ G+ C + I CNN GEC D+ T C C G+ G C+ + I C + C NG C V+ S C C+ + G NCT + + N
Sbjct: 439 QVIDSCTVAVPSNTSESG--VAHVTSTVCG----PNGRCLSQAGGNFTCMCNSGFRGSFCHENVNDCAEGACHNGGTCLDGINS-FQCMCPDGWDGEFCENDVDDCSNHNPCLNGGTCHDLVND-FSCECKNGWKGKTCHSK------ISHCDEATCNNGGECFDV--GDTFRCSCPTGWEGPTCN----IAQSIACMPNPCQNGATC-VISGDSYKCICQSGWEGANCTQDINDCSSHPCYN 660 HSP 2 Score: 88.9669 bits (219), Expect = 4.261e-18 Identity = 72/236 (30.51%), Postives = 101/236 (42.80%), Query Frame = 2
Query: 347 NRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF------ENPCLNVN--------------------------------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
N C NG ++C C GW G C E++++C +PC NGGTC++ N F C C Q+ G+ C +NPC++ C NGGTC+ L N + C+C+ G+ G C + C P C N G+C + + +C C G+ GD C EL V++ C + C NG C L NG C C F G NCT+
Sbjct: 207 NNTCANGGSSVGSPSGYKCLCAPGWTGANCTEDIDECASSPCGNGGTCLNLVNG-FRCTCPPQWTGHTCLVDTDECDDNPCVHARSCKNLFGGYYCGCLPGWTGQNCDIDVNDCEGKCLNGGTCKDLVND-YSCECKPGYTGRRCETEVNECASHP------CLNGGQCRDAID-SYYCVCMDGFAGDSC----ELDVDL-CVPNPCQNGARCVNLPNGDYFCHCSENFEGTNCTL 428 HSP 3 Score: 80.8777 bits (198), Expect = 1.352e-15 Identity = 95/367 (25.89%), Postives = 143/367 (38.96%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ------FENPCLNVN----------------------CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN------------IKIPKTFNEKQLIIKKTKS--PSLCDN-------------LCKASFENGICDQ---QCNTFACNYDGGDC---DPWRKC------YGNDLKHCKGV--FNDGVCNPECNNVDCL 1231
C++ PC+NG +C +A D + C C G+ G++CE +V+ C+ NPC+NG C++ N + C+C+ F G C +PC ++ C G C S G F C C GF G FC C C+N G C N + C C G+ G+ C+ V+ + C NGG C L N CECK + GK C + + N P + I ++ + P+ C N +C++ +E C Q C++ C Y+GG C W +C G D+ C+ + D C E N C+
Sbjct: 356 CASHPCLNGGQCRDAID-SYYCVCMDGFAGDSCELDVDLCVPNPCQNGARCVNLPNGDYFCHCSENFEGTNCTLLKDHCLTSPCQVIDSCTVAVPSNTSESGVAHVTSTVCGPNGRCLSQAGGNFTCMCNSGFRGSFCHENVNDC------AEGACHNGGTCLDGIN-SFQCMCPDGWDGEFCEND----VDDCSNHNPCLNGGTCHDLVNDFS-CECKNGWKGKTCHSKISHCDEATCNNGGECFDVGDTFRCSCPTGWEGPTCNIAQSIACMPNPCQNGATCVISGDSYKCICQSGWEGANCTQDINDCSSHPC-YNGGTCVDGTNWYRCECAAGFAGEDINECQSMPCAKDATCIDEINGYRCM 708 HSP 4 Score: 77.411 bits (189), Expect = 1.521e-14 Identity = 54/166 (32.53%), Postives = 76/166 (45.78%), Query Frame = 2
Query: 323 IVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKE 817
+V + C + PCV+ + + + C C GW G+ C+ +VNDC + C NGGTC D N ++C C + G C+ E N C + C NGG C + + C C GF G+ C + C P C N C PN FC C + G C K+
Sbjct: 275 LVDTDECDDNPCVHARSCKNLFGGYYCGCLPGWTGQNCDIDVNDC-EGKCLNGGTCKDLVN-DYSCECKPGYTGRRCETEVNECASHPCLNGGQCRDAIDSYY-CVCMDGFAGDSCELDVDLCVPNP------CQNGARCVNLPNGDYFCHCSENFEGTNCTLLKD 431 HSP 5 Score: 71.633 bits (174), Expect = 1.041e-12 Identity = 66/249 (26.51%), Postives = 99/249 (39.76%), Query Frame = 2
Query: 356 CVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCI-QNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-----------------------------------------NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
CV+G C + ++ C C W G C++++N C PC+NGG+C + + + C+C + G C+ + + C + C NGGTC +L NG F+C C + G C V C P C N ++ +C C PG+TG CD +++ C NGG CK L N CECK +TG+ C + E +N
Sbjct: 134 CVHGGCSKPWE----CRCDTNWGGLLCDKDLNYCGNHQPCRNGGSCSNAQPDSYKCDCQKGYHGVNCEIDYVQHITLNNTCANGGSSVGSPSGYKCLCAPGWTGANCTEDIDECASSPCGNGGTCLNLVNG-FRCTCPPQWTGHTCLVDTDECDDNPCVHARSCKN-----LFGG--YYCGCLPGWTGQNCD------IDVNDCEGKCLNGGTCKDLVNDYS-CECKPGYTGRRCETEVNECASHPCLN 363 HSP 6 Score: 69.707 bits (169), Expect = 3.943e-12 Identity = 47/154 (30.52%), Postives = 66/154 (42.86%), Query Frame = 2
Query: 323 IVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPG 784
I S C PC NG ++C C GW+G C +++NDC +PC NGGTC+D N + C C + F G + N C ++ C TC NG ++C C G G C + P + + NH + C C G
Sbjct: 609 IAQSIACMPNPCQNGATCVISGDSYKCICQSGWEGANCTQDINDCSSHPCYNGGTCVDGTN-WYRCECAAGFAG---EDINECQSMPCAKDATCIDEING-YRCMCPLGRAGRHCHDEVPTQPCVASGR-----NHSHGSSWKEECNMCHCSNG 752
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004043.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004043.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 96.2857 bits (238), Expect = 3.947e-20 Identity = 48/144 (33.33%), Postives = 72/144 (50.00%), Query Frame = 2
Query: 377 EAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCD 805
E +P C+C G+ G CE ++++C+ PC++GG+C + F C C F G C+ + + CL C+NGG C + + G F C C GF G+ C V C P C N+G C + C+C G +G RC+
Sbjct: 1510 EVLEPAV-CTCTAGYAGTWCEADMDECLSTPCRHGGSCQNLPGG-FACRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQGG-FACDCSAGFSGKICDVTVDNCASSP------CYNNGSC-VNTATGYSCRCPFGMSGARCE 1643 HSP 2 Score: 86.2705 bits (212), Expect = 3.701e-17 Identity = 36/110 (32.73%), Postives = 59/110 (53.64%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFC 667
C + PC +G + F C C G+ G CE +V++C++ PC+NGG C + + F C+C++ F G +C + C + C N G+C + G + C+C +G G C
Sbjct: 1535 CLSTPCRHGGSCQNLPGGFACRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQGG-FACDCSAGFSGKICDVTVDNCASSPCYNNGSCVNTATG-YSCRCPFGMSGARC 1642 HSP 3 Score: 77.0258 bits (188), Expect = 2.946e-14 Identity = 52/189 (27.51%), Postives = 74/189 (39.15%), Query Frame = 2
Query: 443 NVNDCIQ-NPCKNGGTCIDKKNSQFT---------------------CNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
NV+ C +PC NGG C + T C CT+ + G C+ + + CL+ C +GG+C++L G F C+C GF G C C P + LC+N C C G++G CD + C S C+N G C G C C +G C +
Sbjct: 1470 NVDPCAAPSPCANGGHCAKRLAVGPTTTVVESASVILVSHEVLEPAVCTCTAGYAGTWCEADMDECLSTPCRHGGSCQNLPGG-FACRCLPGFSGTACETDVDECLEGPCQNGGLCHN-------TQGGFACDCSAGFSGKICDVTVD-----NCASSPCYNNGSCVNTATGYS-CRCPFGMSGARCEL 1644
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004042.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 96.2857 bits (238), Expect = 3.953e-20 Identity = 48/144 (33.33%), Postives = 72/144 (50.00%), Query Frame = 2
Query: 377 EAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCD 805
E +P C+C G+ G CE ++++C+ PC++GG+C + F C C F G C+ + + CL C+NGG C + + G F C C GF G+ C V C P C N+G C + C+C G +G RC+
Sbjct: 1510 EVLEPAV-CTCTAGYAGTWCEADMDECLSTPCRHGGSCQNLPGG-FACRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQGG-FACDCSAGFSGKICDVTVDNCASSP------CYNNGSC-VNTATGYSCRCPFGMSGARCE 1643 HSP 2 Score: 86.2705 bits (212), Expect = 3.705e-17 Identity = 36/110 (32.73%), Postives = 59/110 (53.64%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFC 667
C + PC +G + F C C G+ G CE +V++C++ PC+NGG C + + F C+C++ F G +C + C + C N G+C + G + C+C +G G C
Sbjct: 1535 CLSTPCRHGGSCQNLPGGFACRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQGG-FACDCSAGFSGKICDVTVDNCASSPCYNNGSCVNTATG-YSCRCPFGMSGARC 1642 HSP 3 Score: 77.0258 bits (188), Expect = 2.949e-14 Identity = 52/189 (27.51%), Postives = 74/189 (39.15%), Query Frame = 2
Query: 443 NVNDCIQ-NPCKNGGTCIDKKNSQFT---------------------CNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
NV+ C +PC NGG C + T C CT+ + G C+ + + CL+ C +GG+C++L G F C+C GF G C C P + LC+N C C G++G CD + C S C+N G C G C C +G C +
Sbjct: 1470 NVDPCAAPSPCANGGHCAKRLAVGPTTTVVESASVILVSHEVLEPAVCTCTAGYAGTWCEADMDECLSTPCRHGGSCQNLPGG-FACRCLPGFSGTACETDVDECLEGPCQNGGLCHN-------TQGGFACDCSAGFSGKICDVTVD-----NCASSPCYNNGSCVNTATGYS-CRCPFGMSGARCEL 1644
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002643.1 (pep scaffold:Pmarinus_7.0:GL478752:33855:40482:1 gene:ENSPMAG00000002413.1 transcript:ENSPMAT00000002643.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 84.3445 bits (207), Expect = 9.808e-18 Identity = 68/207 (32.85%), Postives = 101/207 (48.79%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICEC-KGEFTGKNCTIPLKE 952
C++ PC++G C+ A D F C C G+ G+ CE +V C PC N C+D+ + C C F G C+ + N C + C +GGTC + + + C C GF GE C + C P C+N C + + C C GYTG C+ + + C+S C NGGVC L + S C+C + + GK+C + + E
Sbjct: 1 CASGPCLHGGTCLPAADGGFSCRCAPGYSGDNCEASVGGCASGPCLNDAVCVDEPGG-YKCYCVPGFQGRHCEIDINECASEPCLHGGTCTNGRD-RYSCACPDGFAGERCQLDTNECASQP------CHNGATC-VDLDGKFECVCPRGYTGAMCETEVDE-----CESGPCQNGGVCIDLVD-SYTCDCLETGYEGKDCELEILE 192 HSP 2 Score: 81.2629 bits (199), Expect = 1.085e-16 Identity = 66/233 (28.33%), Postives = 103/233 (44.21%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKC-RYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD------------------NGSPI-CECKGEFTGKNCTIPLKETRKEALIN 976
C++ PC++G + C+C G+ GE C+ + N+C PC NG TC+D + +F C C + G +C+ E + C + C+NGG C L + + C C G+ G+ C ++ + C P + C I + C C PG+ GD C++ C + C NGG C L N S C C TG+NC++ L E + +N
Sbjct: 78 CASEPCLHGGTCTNGRDRYSCACPDGFAGERCQLDTNECASQPCHNGATCVD-LDGKFECVCPRGYTGAMCETEVDECESGPCQNGGVCIDLVD-SYTCDCLETGYEGKDCELEILECASNPCRHNSTC-------IEGILNFTCICWPGFAGDACEEDVNE-----CGDEPCMNGGQCIELSKPDFYGKLSELPGTFHYANASGFTCRCLPGTTGENCSVNLDECESQPCLN 296 HSP 3 Score: 78.9518 bits (193), Expect = 7.732e-16 Identity = 75/223 (33.63%), Postives = 103/223 (46.19%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNC-TSQFIGNLCQFEN-PCLNVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC------DIYPNMT-------------LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDN-GSPICECKGEFTG 925
+ + C+++PC NG D +F C C G+ G CE V++C PC+NGG CID +S +TC+C + + G C+ E C + C + TC E + N F C C GF G+ C C E C N G+C D Y ++ C+C PG TG+ C + C+S C NGG C +DN GS CEC FTG
Sbjct: 111 LDTNECASQPCHNGATCVDLDGKFECVCPRGYTGAMCETEVDECESGPCQNGGVCIDLVDS-YTCDCLETGYEGKDCELEILECASNPCRHNSTCIEGILN--FTCICWPGFAGDACEEDVNEC------GDEPCMNGGQCIELSKPDFYGKLSELPGTFHYANASGFTCRCLPGTTGENCSVNLDE-----CESQPCLNGGSC--IDNIGSFSCECAPGFTG 317
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO46513 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPI0]) HSP 1 Score: 104.375 bits (259), Expect = 9.432e-25 Identity = 77/221 (34.84%), Postives = 113/221 (51.13%), Query Frame = 2
Query: 335 KLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPK 991
+ CS++PC NG + + C+C G+ G+ CE++VN+C +NPCKNGG C + ++ ++C C + F G C+ + N C C+NGG C++ E+G + C C+ GF G+ C C P K +C N HG C C G+TG C++ C + C NGGVCK ++G C CK FTGK C + E K N + K
Sbjct: 2 ETCSSKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKN-EHGGYSCACKAGFTGKNCEQDVNECSENPCKNGGVCKN-EHGGYSCACKAGFTGKNCEQDVNECSENPCKNGGVCKNEHG--------GYSCACKAGFTGKNCEQDVNE-----CSKNPCQNGGVCK-NEHGGYSCACKAGFTGKICEQDVNECNKNPCQNGGVCK 206
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO48851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RHH9]) HSP 1 Score: 111.309 bits (277), Expect = 1.512e-24 Identity = 91/283 (32.16%), Postives = 135/283 (47.70%), Query Frame = 2
Query: 335 KLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKT---------------FNEKQLIIKKTKSP----SLCDN-------LCKASFENGICDQQCN 1099
+ CS++PC NG + + C+C G+ G+ CE++VN+C +NPCKNGG C + ++ ++C C + F G C+ + N C C+NGG C++ E+G + C C+ GF G+ C C P + +C N HG C C G+TG C++ C + C NGGVCK ++G C CK FTGKNC + E K N + K N +Q + + +K+P +C N CKA F IC+Q N
Sbjct: 990 ETCSSKPCKNGGTCREVNGAYSCTCKSGFTGKNCEQDVNECSKNPCKNGGVCKN-EHGGYSCACKAGFTGKNCEQDVNECNKNPCQNGGVCKN-EHGGYSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKNEHG--------GYSCACKAGFTGKNCEQDVNE-----CSKNPCKNGGVCK-NEHGGYSCACKAGFTGKNCEQDMNECSKNPCQNGGVCKNKHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSCTCKAGFTGKICEQDVN 1256 HSP 2 Score: 105.916 bits (263), Expect = 6.340e-23 Identity = 79/219 (36.07%), Postives = 111/219 (50.68%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPK 991
CS PC NG + + C+C G+ G+ CE++VN+C NPCKNGG C + ++ ++C C + F G C+ + N C C+NGG C++ E+G + C C+ GF G+ C C V P K +C N HG C C G+TG C++ C + C NGGVCK ++G C CK FTGKNC + E K N + K
Sbjct: 220 CSKNPCKNGGVCKNEHGGYSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKN-EHGGYSCACKAGFTGKNCEQDVNECSVNPCKNGGVCKN-EHGGYSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHG--------GYSCACKAGFTGKNCEQDVNE-----CSKNPCKNGGVCK-NEHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCK 422 HSP 3 Score: 104.76 bits (260), Expect = 1.693e-22 Identity = 74/200 (37.00%), Postives = 106/200 (53.00%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
CS PC NG + + C+C G+ G+ CE++VN+C +NPCKNGG C + ++ ++C C + F G C+ + N C C+NGG C++ E+G + C C+ GF+G+ C C P K +C N HG C C G+TG C++ C + C NGGVCK ++G C CK FTGKNC
Sbjct: 372 CSKNPCKNGGVCKNEHGGYSCACKAGFTGKNCEQDVNECSKNPCKNGGVCKN-EHGGYSCACKAGFTGKNCEQDVNECSKNPCQNGGVCKN-EHGGYSCACKAGFMGKNCEQDVNECSKNPCKNGGVCKNEHG--------GYSCACKAGFTGKNCEQDVNE-----CSKNPCKNGGVCK-NEHGGYSCACKAGFTGKNC 555 HSP 4 Score: 96.2857 bits (238), Expect = 5.499e-20 Identity = 72/206 (34.95%), Postives = 106/206 (51.46%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
CS PC NG + + C+C G+ G+ CE++VN+C +NPC+NGG C + ++ ++C C + F G C+ + N C C+NGG C++ E+G + C C+ GF G+ C C P + +C N HG C C G+TG C++ C + C NGGVCK ++G C CK FTGK C + E
Sbjct: 730 CSKNPCQNGGVCKNEHGGYSCACKAGFTGKICEQDVNECNKNPCQNGGVCKN-EHGGYSCTCKAGFTGKNCEQDVNECNKNPCQNGGVCKN-EHGGYSCTCKAGFTGKNCEQDVNECNKNPCQNGGVCKNEHG--------GYSCTCKAGFTGKNCEQDVNE-----CSKNPCKNGGVCK-NEHGGYSCACKAGFTGKICEQEICE 919 HSP 5 Score: 87.0409 bits (214), Expect = 3.941e-17 Identity = 75/232 (32.33%), Postives = 107/232 (46.12%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKK-------------------------KELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC-TIPLKE 952
CS PC NG + + C+C G+ G+ CE++VN+C +NPCKNGG C ++ + ++C C + F G C+ + N C C+NGG C++ E+G + C C+ GF G+ C C P K +C N HG C C G+TG +K P + CK + C N G C + GS C C E+TGK+C T KE
Sbjct: 1258 CSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNE-HGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKN-EHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHG--------GYSCTCKAGFTGKTANKMLTNVPASTRVIMAESALTAMEDTVVNARPDKNECKVNPCLNNGKC-INTPGSYKCNCIDEYTGKHCETAKYKE 1478 HSP 6 Score: 86.6557 bits (213), Expect = 4.589e-17 Identity = 71/219 (32.42%), Postives = 104/219 (47.49%), Query Frame = 2
Query: 443 NVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQ 1093
+VN+C +NPC+NGG C + ++ ++C C + F G +C+ + N C C+NGG C++ E+G + C C+ GF G+ C C P + +C N HG C C G+TG C++ C + C NGGVCK ++G C CK FTGKNC + E K N + K + CKA F IC+Q+
Sbjct: 726 DVNECSKNPCQNGGVCKN-EHGGYSCACKAGFTGKICEQDVNECNKNPCQNGGVCKN-EHGGYSCTCKAGFTGKNCEQDVNECNKNPCQNGGVCKNEHG--------GYSCTCKAGFTGKNCEQDVNE-----CNKNPCQNGGVCK-NEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNEHGGYSC------------ACKAGFTGKICEQE 916 HSP 7 Score: 76.6406 bits (187), Expect = 5.304e-14 Identity = 62/194 (31.96%), Postives = 94/194 (48.45%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGE---------------------FCAVQNIACPVIPKK---KRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSD 847
CS PC NG + + C+C G+ G+ CE++VN+C +NPCKNGG C ++ + ++C C + F G C+ + N C C+NGG C++ E+G + C C+ GF G+ A+++ P K K C N+G+C P + C C YTG C+ K E+GC D
Sbjct: 1296 CSKNPCKNGGVCKNEHGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKNE-HGGYSCTCKAGFTGKNCEQDVNECSKNPCKNGGVCKN-EHGGYSCTCKAGFTGKTANKMLTNVPASTRVIMAESALTAMEDTVVNARPDKNECKVNPCLNNGKCINTPG-SYKCNCIDEYTGKHCETAKYK--ELGCYKD 1484 HSP 8 Score: 60.4622 bits (145), Expect = 4.894e-9 Identity = 63/184 (34.24%), Postives = 89/184 (48.37%), Query Frame = 2
Query: 407 CWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELC-NNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C+H W G+TC N ++N GG + + N C+ ++ GN +F+ N C C+NGG C++ E+G + C C+ GF G+ C C V P K +C N HG C C G+TG C++ C + C NGGVCK ++G C CK FTGKNC + E
Sbjct: 172 CYH-WSGKTCHWNNAIRVRNC---GGFYVYELNRPPVCH--LRYCGNA-EFDVNECSKNPCKNGGVCKN-EHGGYSCACKVGFTGKNCEQDVNECSVNPCKNGGVCKNEHG--------GYSCACKAGFTGKNCEQDVNE-----CSVNPCKNGGVCK-NEHGGYSCACKVGFTGKNCEQDVNE 333
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO36196 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJC3]) HSP 1 Score: 103.605 bits (257), Expect = 1.128e-23 Identity = 106/353 (30.03%), Postives = 143/353 (40.51%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN------------IKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACN----YDGGDCDPWRKCYGNDLKHCKG--VFNDGVCN-----------PECNNVDCLFDGEDCHKSSC-KFHKCSELYQNKIC 1306
C++ PCVNG F C+C G+ G CE ++N+C NPC NGGTC D+ NS F+C C S + G C+ + N C + C NGGTC L NG + CKC+ G+ G C + I + C N G C N C C PGY G +C+ C+++ C NGG C N S C C +TG C + E +N P +N + I + S G C Q N+F+C Y G C+ D+ C N G C P N C D ++C + C CS+L N C
Sbjct: 5 CASNPCVNGGTCTDLVNGFHCTCPPGYNGTKCEIDINECDSNPCANGGTCADQVNS-FSCTCVSGYTGLQCKTDINECASNPCLNGGTCNDLVNG-YNCKCQPGYNGTTCEID------INECASNQCVNGGTCTDLVNG-FNCTCPPGYNGTKCEININE-----CENNPCVNGGTCADQVN-SFSCTCVSGYTGLKCETDINECASNPCVNGGTCTDLVNGFHCTCPPGYNGTKCEIDINECES------NPCANGGTCADQVNSFSCTCVLGYTGLKCE-------TDIDECASNPCINGGTCTELVNGFKCTCVPGYNGTRCEIDIDECSSNPCLNGATCSDLLNNYTC 329 HSP 2 Score: 83.9593 bits (206), Expect = 3.494e-17 Identity = 59/156 (37.82%), Postives = 81/156 (51.92%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCD 805
C++ PCVNG F C+C G+ G CE ++N+C NPC NGGTC D+ NS F+C C + G C+ + + C + C NGGTC L NG F+C C G+ G C + C P C+ D+ N T C C G+ G+RC+
Sbjct: 195 CASNPCVNGGTCTDLVNGFHCTCPPGYNGTKCEIDINECESNPCANGGTCADQVNS-FSCTCVLGYTGLKCETDIDECASNPCINGGTCTELVNG-FKCTCVPGYNGTRCEIDIDECSSNPCLNGATCS-----DLLNNYT--CTCASGFQGERCE 341 HSP 3 Score: 73.9442 bits (180), Expect = 7.851e-14 Identity = 65/180 (36.11%), Postives = 81/180 (45.00%), Query Frame = 2
Query: 443 NVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
++N+C NPC NGGTC D N F C C + G C+ + N C + C NGGTC N F C C G+ G C C P C N G C+ N CKC PGY G C+ ++I C S+ C NGG C L NG C C + G C I + E +N
Sbjct: 1 DINECASNPCVNGGTCTDLVNG-FHCTCPPGYNGTKCEIDINECDSNPCANGGTCADQVN-SFSCTCVSGYTGLQCKTDINECASNP------CLNGGTCNDLVNG-YNCKCQPGYNGTTCE------IDINECASNQCVNGGTCTDLVNGFN-CTCPPGYNGTKCEININECENNPCVN 164 HSP 4 Score: 56.6102 bits (135), Expect = 3.200e-8 Identity = 34/95 (35.79%), Postives = 48/95 (50.53%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL------CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ 556
+N F C+L K C++ PC+NG F+C+C G+ G CE ++++C NPC NG TC D N +TC C S F G C+
Sbjct: 248 VNSFSCTCVLGYTGLKCETDIDECASNPCINGGTCTELVNGFKCTCVPGYNGTRCEIDIDECSSNPCLNGATCSDLLN-NYTCTCASGFQGERCE 341
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO34703 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNM7]) HSP 1 Score: 103.99 bits (258), Expect = 2.188e-22 Identity = 74/206 (35.92%), Postives = 92/206 (44.66%), Query Frame = 2
Query: 338 LCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C + PC NG +RC C G+ G+ CE ++C NPC NGG C+DK N F C C S F G C+ C C N G C + G FQC C G+ G+FC V C K C N G+C N + C C GY+G RC+ K GC+ D C NG C G C C F+G C + E
Sbjct: 918 FCDSNPCNNGAQCNNMVDGYRCMCKSGFTGKNCEVEEDECTTNPCANGGACVDKING-FVCTCPSGFTGQFCEKATVDCKPGACRNNGKCVEIPGG-FQCLCSDGYEGDFCEVNTNEC------KSSPCLNGGKCTDGVN-SFTCNCPAGYSGGRCEDKTN-----GCRPDSCLNGATCTETSYGH-RCACVAGFSGNRCETDINE 1108 HSP 2 Score: 80.1073 bits (196), Expect = 4.949e-15 Identity = 58/148 (39.19%), Postives = 74/148 (50.00%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRC 802
NGKCVE F+C C G++G+ CE N N+C +PC NGG C D NS FTCNC + + G C+ + N C +C NG TC G +C C GF G C C P C N+G C + C C PG++G C
Sbjct: 1003 NGKCVE-IPGGFQCLCSDGYEGDFCEVNTNECKSSPCLNGGKCTDGVNS-FTCNCPAGYSGGRCEDKTNGCRPDSCLNGATCTETSYG-HRCACVAGFSGNRCETDINECASTP------CANNGLC-VDKEGGFTCLCKPGFSGTTC 1140 HSP 3 Score: 70.4774 bits (171), Expect = 3.689e-12 Identity = 61/178 (34.27%), Postives = 77/178 (43.26%), Query Frame = 2
Query: 446 VNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+N C NPC NG C + + + C C S F G C+ E+ C C NGG C NG F C C GF G+FC + C K C N+G+C P C C GY GD C+ CKS C NGG C N S C C ++G C R ++ +N
Sbjct: 916 INFCDSNPCNNGAQCNNMVDG-YRCMCKSGFTGKNCEVEEDECTTNPCANGGACVDKING-FVCTCPSGFTGQFCEKATVDC------KPGACRNNGKCVEIPG-GFQCLCSDGYEGDFCEVNTNE-----CKSSPCLNGGKCTDGVN-SFTCNCPAGYSGGRCEDKTNGCRPDSCLN 1078 HSP 4 Score: 65.4698 bits (158), Expect = 1.529e-10 Identity = 43/116 (37.07%), Postives = 59/116 (50.86%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFC 667
V++ C + PC+NG KC + + F C+C G+ G CE+ N C + C NG TC + C C + F GN C+ + N C + C N G C E G F C C+ GF G C
Sbjct: 1028 VNTNECKSSPCLNGGKCTDGVN-SFTCNCPAGYSGGRCEDKTNGCRPDSCLNGATCTETSYGH-RCACVAGFSGNRCETDINECASTPCANNGLCVDKEGG-FTCLCKPGFSGTTC 1140
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Match: EDO48147 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKD3]) HSP 1 Score: 97.0561 bits (240), Expect = 4.456e-22 Identity = 73/201 (36.32%), Postives = 97/201 (48.26%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT-LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C+ PC N G C + +F C+C G++G+ C ++ C +NPC+NGGTCI S +TC CT G C+ + C + C+N C++ + F C C GF G+ C + C P C N G C + N T FC C PGYTG C L V+ C S C NG C + G CEC GKNC
Sbjct: 4 CATNPCKNSGTCTSVYS-DFNCTCSSGFQGKDCSLDIEPCTKNPCQNGGTCIPSGPSVYTCTCTPGVTGANCETVADQCSSNPCQNNAECKTAGS-TFTCSCTAGFTGDLCDKELQPCVPSP------CGNGGTCRVINNGTDYFCTCAPGYTGANC----TLDVDE-CSSSPCQNGASC-IKKVGRYFCECSTAHVGKNC 190 HSP 2 Score: 93.2041 bits (230), Expect = 1.074e-20 Identity = 77/235 (32.77%), Postives = 98/235 (41.70%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGM-FQCKCRYGFIGEFCAVQNIACPVIP---------KKKRELC------------NNHGECDIYPNMT----------LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP-ICECKGEFTGKNCTI 940
C+ PC NG C+ + + C+C G G CE + C NPC+N C S FTC+CT+ F G+LC E PC+ C NGGTC + NG + C C G+ G C + C P K R C N EC P FC+C + G C KK + C S C NGG C + +GS C C +TGKNCT
Sbjct: 42 CTKNPCQNGGTCIPSGPSVYTCTCTPGVTGANCETVADQCSSNPCQNNAEC-KTAGSTFTCSCTAGFTGDLCDKELQPCVPSPCGNGGTCRVINNGTDYFCTCAPGYTGANCTLDVDECSSSPCQNGASCIKKVGRYFCECSTAHVGKNCHKNVDECSSSPCQNGASCIKKVGRYFCECSTAHVGKNCHKKPDP-----CLSKPCANGGTCSPISSGSDYTCACAAGYTGKNCTA 270 HSP 3 Score: 90.8929 bits (224), Expect = 7.275e-20 Identity = 65/179 (36.31%), Postives = 82/179 (45.81%), Query Frame = 2
Query: 446 VNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP-ICECKGEFTGKNCTIPLKETRKEALIN 976
V+ C NPCKN GTC S F C C+S F G C + PC C+NGGTC ++ C C G G C C P C N+ EC T C C G+TGD CDK+ + C C NGG C+V++NG+ C C +TG NCT+ + E N
Sbjct: 1 VDKCATNPCKNSGTCTSVY-SDFNCTCSSGFQGKDCSLDIEPCTKNPCQNGGTCIPSGPSVYTCTCTPGVTGANCETVADQCSSNP------CQNNAECKTA-GSTFTCSCTAGFTGDLCDKELQP-----CVPSPCGNGGTCRVINNGTDYFCTCAPGYTGANCTLDVDECSSSPCQN 166 HSP 4 Score: 63.1586 bits (152), Expect = 1.343e-10 Identity = 50/168 (29.76%), Postives = 77/168 (45.83%), Query Frame = 2
Query: 335 KLCSNRPCVNGKCVEAFD--PEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECD-IYPNMTLFCKCDPGYTGDRCDKKKELPV 826
+ C PC NG + ++ C+C G+ G C +V++C +PC+NG +CI KK ++ C C++ +G C + C + C+NG +C + G + C+C +G+ C + C P C N G C I C C GYTG C K V
Sbjct: 117 QPCVPSPCGNGGTCRVINNGTDYFCTCAPGYTGANCTLDVDECSSSPCQNGASCI-KKVGRYFCECSTAHVGKNCHKNVDECSSSPCQNGASCIK-KVGRYFCECSTAHVGKNCHKKPDPCLSKP------CANGGTCSPISSGSDYTCACAAGYTGKNCTAGKPRDV 276
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Match: notch1b (notch receptor 1 [Source:NCBI gene;Acc:101161732]) HSP 1 Score: 203.371 bits (516), Expect = 2.977e-52 Identity = 247/995 (24.82%), Postives = 401/995 (40.30%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDC--IQNP------CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGT--CESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMT--LFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE---------------TRKEALINIKIPKTFNEKQLIIKKTKSPSLCDN---------------LCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSF----------FSNEGLTKCSTQTKLYELDLVLMT-------------------------------TMQNFTKYKSEFLQKLSSSLRMVVTVFNVT--EINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEY-----QIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDS--------------LESTDGIHPI------DAGL--GDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLA--DLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
C ++PC NG C++ D ++CSC G +G CE NV+DC +P C N G C+D+ + C C S ++G C+ + N CL+ C+ GT C L N ++C+CR G+ G+ C V K C N G C + N C+C PG+TG C+ + C S C NGG C + + SP C C FTG C P T + P FN I P + C+A N C+ CN C +D GDC DPW+ C + C FNDG C+ +C+N CL+DG DC + + C + Y + CD+ CN+ +C +DG DC + E L ++ T L EL VL T ++ ++ + +E L + SL V T E++ ++ L ++ QC +CF S + FL A +E L +PF + V + + + + PIY ++ +L F + R + G+L W P +T TS G + LK K + +P + +GE +P TD D++ R++ + + L I+ + + DG P+ GL G+ ++ D YQ ++L + GE+ +H+AAR + + A + + D GRTPL +++AADA + Q+LI + +++ + TT LI A +L ++ M+ L++ + VN +D G+S +HW+A + + + + + A D+++N++++PLFLAA EG+ ++ K LL +F I MD P+ IA+++ ++I L+ E
Sbjct: 1187 CFSQPCQNGGTCIDLID-TYKCSCPRGTQGVHCEVNVDDCSPFTDPLTKEPKCFNKGKCVDRVGG-YHCICPSGYVGERCEGDVNECLSNPCDPRGTLSCIQLTNN-YRCECRAGYTGQRCDT------VFDGCKSRPCRNGGTCAVASNTPHGFICRCPPGFTGSTCEYDSQT-----CGSLRCRNGGTC-ISGHKSPKCLCPPSFTGPECRHPTDSACNSNPCYNGGTCELTPEAPYYRCICPFKFNGLLCHILDNGFPGGVGSSVPTLPEVTASCGIPQCEAYKHNKYCNTVCNNHECGWDNGDCSLNFDDPWKNCSAS--LQCWRYFNDGKCDSQCDNAGCLYDGFDCQNLEGQCNPLYDQYCRDHYADNHCDQGCNNAECEWDGLDCAKNLPEKLAVGRLVLVVHIRPEQLLN-TSSTFLRELSRVLRTNVLFRRDSNGEVMVYPYYGDEHELKKYNVKRSVDSWMEAPAEVLDVMKRSLYGAVGSSRRTKRELDHLQIKGSVVHLEMDNRQCFQQSSECFQSTTDAAAFLGA-LESSGKLDVPFTIEAVYSNVEPKNAQGLYPIYLVLAGVAVLAFLGVGMVAARKRRHEHGRL---------WLPEGFKTTETSKKKRREPVGEDSV-GLKPLKNSHISLMDDVPTE--WGEDEP-TDVKHFKQFDEQAALDADDQTDHRQWTQQHLDAADLRVPSIAPTPPQGEIENDCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDASANVINDFIYQGANLH---NQTDRTGETALHLAARYARSDAAKRLLEASADANIQ--DNMGRTPLHAAVAADA-QGVFQILIRNRATDLDARMH-------------------DGTTPLILAARLAAEGMVEELINCHADVNAIDDFGKSALHWAAA-----VNNVEAAIVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLEHFANREITDHMD---RLPRDIAQDRMHHDIVRLMDE 2116 HSP 2 Score: 100.523 bits (249), Expect = 1.002e-20 Identity = 124/445 (27.87%), Postives = 165/445 (37.08%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGW------------------------------------------------KGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVI--PKKKRELCNNHGEC----------------------DIY--------PNMTLF---------CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGIC----DQQCNTFACNYDGGDCD-----PWRKC-----YGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHKCSELYQNKICDEECNSPQCGFDGGDC 1354
C++ PC NG +RC+C GW G CEE V++C NPC+NG TC D ++C C F+G C E N C + C+NGGTC L + ++C C G G C V C P K C N G+C D+ P TL C+C GYTG RCD V GCKS C NGG C V N +P IC C FTG C E + +++ I KSP LC SF C D CN+ C Y+GG C+ P+ +C + L H + ++G ++V L + +SC +C NK C+ CN+ +CG+D GDC
Sbjct: 1063 CNSSPCKNGGSCSQSGTTYRCNCETGWTGLYCDVPSVSCEVAAKQRGVDITQLCRNAGRCLDAGNVHRCHCQAGYTGSYCEEQVDECTPNPCQNGATCTDFLGG-YSCKCLPGFLGTNCSVEINECFSQPCQNGGTCIDLID-TYKCSCPRGTQGVHCEVNVDDCSPFTDPLTKEPKCFNKGKCVDRVGGYHCICPSGYVGERCEGDVNECLSNPCDPRGTLSCIQLTNNYRCECRAGYTGQRCDT-----VFDGCKSRPCRNGGTCAVASN-TPHGFICRCPPGFTGSTC-----EYDSQTCGSLRC----RNGGTCISGHKSPKC---LCPPSFTGPECRHPTDSACNSNPC-YNGGTCELTPEAPYYRCICPFKFNGLLCH---ILDNGFPGGVGSSVPTLPE----VTASCGIPQCEAYKHNKYCNTVCNNHECGWDNGDC 1479 HSP 3 Score: 96.6709 bits (239), Expect = 1.272e-19 Identity = 78/249 (31.33%), Postives = 107/249 (42.97%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC------------DIYPNMTLF------------------------CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
CS+ PC G C + F C C G+ G CE N+N+C+ PC+NGGTC D+ N+ + C+C G C+ + C N C+N GTC NG ++C C G+ G C + C P C N G C D Y + T F C CD G++G CD C+S+ C NGG CK + +G +C C+ FTG NC + E +N
Sbjct: 570 CSSDPCHYGTCKDGL-ASFSCDCTPGYTGRLCETNINECLSLPCRNGGTCQDRPNA-YICSCPKGTGGINCEINIDDCKNNLCKN-GTCIDRING-YECACEPGYTGTMCNIDIDECAANP------CRNGGTCIDGINAFTCKCPDGYQDPTCFSQVNECLSNPCIHGHCEDKINGYKCLCDSGWSGKNCDINNNE-----CESNPCMNGGTCKDMTSGY-VCTCRMGFTGPNCQTNINECASNPCLN 802 HSP 4 Score: 93.5893 bits (231), Expect = 1.086e-18 Identity = 68/219 (31.05%), Postives = 99/219 (45.21%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGM-FQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+++ C + PC+NG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ PC + C++GG C E+ + F C C G+ G+ C V C P C N + C C PG+TG C+ + CK + C NGG+CK N +C C F G C + E N
Sbjct: 752 INNNECESNPCMNGGTCKDMTSGYVCTCRMGFTGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCVLPYTGENCETLMAPCHSKPCKHGGVCRESEDYLSFSCACPEGWQGQTCEVDIKECVKNPCLNGATCQNT-------LGSYHCSCKPGFTGRNCEANMD-----DCKPNPCNNGGLCKDEVNDF-LCTCLLGFRGTTCEEDINECESSPCKN 956 HSP 5 Score: 90.8929 bits (224), Expect = 8.958e-18 Identity = 72/204 (35.29%), Postives = 89/204 (43.63%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
V K C PC+NG + + CSC G+ G CE N++DC NPC NGG C D+ N F C C F G C+ + N C + C+NG C N + C C GF G C P C N G C N C C PG+TG+ C C S C NGG C+ G+ C C +TG NC
Sbjct: 868 VDIKECVKNPCLNGATCQNTLGSYHCSCKPGFTGRNCEANMDDCKPNPCNNGGLCKDEVN-DFLCTCLLGFRGTTCEEDINECESSPCKNGANCTDCVNS-YTCTCPAGFSGINCENN------TPDCTESSCFNGGTCVDGIN-AFTCLCPPGFTGNYCQHDINE-----CDSKPCMNGGTCQD-SYGTYKCTCPHGYTGLNC 1056 HSP 6 Score: 88.5817 bits (218), Expect = 4.490e-17 Identity = 74/240 (30.83%), Postives = 106/240 (44.17%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ---FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCA-----VQNIAC--------------PVIPKKKREL------------CNNHGECDIYP-NMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C+ PC+NG C++ + + CSC G+ G+ C N+NDC + C+NGGTC+D N+ + C C +F G LC E + C+NGGTC + G +QC C G+ G C+ + AC PK + L C CD P FC C PGY G CDK + E + C + G C + GS C+C+ + G C + + E
Sbjct: 222 CNPSPCLNGGTCIQKGETSYECSCVPGFTGKNCSSNINDCPGHECQNGGTCVDGVNT-YNCQCKPEFTGQLCMDDVDECQLMPNACQNGGTCHNTY-GSYQCVCVNGWTGNDCSKNIDDCADAACYKGSTCHDRVASFYCECPKGRTGLLCQLDDACISNPCQKGSNCDTNPITGNHFCTCPPGYFGPSCDKDVD---ECSLGPNPCEHAGKC-LNTKGSFQCKCQRGYVGPRCEMDVNE 455 HSP 7 Score: 87.8113 bits (216), Expect = 6.346e-17 Identity = 70/211 (33.18%), Postives = 101/211 (47.87%), Query Frame = 2
Query: 326 VSSKLCSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
+++ C+N PC+N GKC++ + F C C G+ G C+ ++++C PCKNG C D N ++TC CT + G C+ E N C + C G + L + F C C G+ G C C +P C N G C PN C C G G C E+ ++ CK++ C N G C NG C C+ +TG C I + E
Sbjct: 489 INTDECANGPCLNSGKCIDKIN-GFHCECPTGFTGSLCQTDIDECASTPCKNGAKCTDGPN-KYTCECTEGYAGQHCETEINECSSDPCHYGTCKDGLAS--FSCDCTPGYTGRLCETNINECLSLP------CRNGGTCQDRPN-AYICSCPKGTGGINC----EINID-DCKNNLCKN-GTCIDRINGYE-CACEPGYTGTMCNIDIDE 681 HSP 8 Score: 83.5741 bits (205), Expect = 1.335e-15 Identity = 69/204 (33.82%), Postives = 86/204 (42.16%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDP----EFRCSCWHGWKGETCEENVND-CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCT 937
C+N PC NG A +F C+C G+ C +N C +PC+N GTC + + C C G C +PC + C NGG C SL F C C F G+ C C + P LC N G C I C+C Y G C+ + LP C C NGG C S C C FTGKNC+
Sbjct: 63 CNNSPCANGGTCRAVSKGNTVDFNCTCKLGFTDRRCMTPINTACFSSPCRNEGTCEPEGLQGYRCRCPPGLAGEDCSKADPCASNPCANGGRC-SLFESFFICTCTPFFSGQTCKQDINECDIQPP----LCKNGGLC-INEVGGYRCQCPAEYNGKHCETRY-LP----CNPSPCLNGGTCIQKGETSYECSCVPGFTGKNCS 255 HSP 9 Score: 79.7221 bits (195), Expect = 1.919e-14 Identity = 55/165 (33.33%), Postives = 73/165 (44.24%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAVQ-NIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C N G C + C C ++G+ CQF +PC N C NGGTC ++ G F C C+ GF C N AC P C N G C+ C+C PG G+ C K C S+ C NGG C + ++ IC C F+G+ C + E
Sbjct: 30 CLNQGRCEATPDGNGECKCRDGYVGSRCQFHDPCNNSPCANGGTCRAVSKGNTVDFNCTCKLGFTDRRCMTPINTACFSSP------CRNEGTCEPEGLQGYRCRCPPGLAGEDCSKADP------CASNPCANGGRCSLFESFF-ICTCTPFFSGQTCKQDINE 181 HSP 10 Score: 75.8702 bits (185), Expect = 3.265e-13 Identity = 77/296 (26.01%), Postives = 111/296 (37.50%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKL------CSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLN--------------------------------------------------VNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
+N F+ CLL + C + PC NG C + + + C+C G+ G CE N DC ++ C NGGTC+D N+ FTC C F GN CQ + PC+N NCE G+ G +C V +++C V K++ +LC N G C N+ C C GYTG C+++ + C + C NG C G C+C F G NC++ + E + N
Sbjct: 926 VNDFLCTCLLGFRGTTCEEDINECESSPCKNGANCTDCVN-SYTCTCPAGFSGINCENNTPDCTESSCFNGGTCVDGINA-FTCLCPPGFTGNYCQHDINECDSKPCMNGGTCQDSYGTYKCTCPHGYTGLNCQDLVNWCNSSPCKNGGSCSQSGTTYRCNCET------------------GWTGLYCDVPSVSCEVAAKQRGVDITQLCRNAGRCLDAGNVHR-CHCQAGYTGSYCEEQVDE-----CTPNPCQNGATCTDFLGGY-SCKCLPGFLGTNCSVEINECFSQPCQN 1194 HSP 11 Score: 74.3294 bits (181), Expect = 8.398e-13 Identity = 60/184 (32.61%), Postives = 81/184 (44.02%), Query Frame = 2
Query: 395 FRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
+RC C + G+ CE C +PC NGGTCI K + + C+C F G C N C C+NGGTC N + C+C+ F G+ C C ++P C N G C + Y + C C G+TG+ C K + C C+ G C S CEC TG C +
Sbjct: 202 YRCQCPAEYNGKHCETRYLPCNPSPCLNGGTCIQKGETSYECSCVPGFTGKNCSSNINDCPGHECQNGGTCVDGVN-TYNCQCKPEFTGQLCMDDVDECQLMPNA----CQNGGTCHNTY--GSYQCVCVNGWTGNDCSKNID-----DCADAACYKGSTCHDR-VASFYCECPKGRTGLLCQL 372
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:101162450]) HSP 1 Score: 183.341 bits (464), Expect = 4.243e-46 Identity = 235/940 (25.00%), Postives = 380/940 (40.43%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCK--NGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGM--FQCKCRYGFIGEFCAVQNIACPVIPKKKREL-CNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKC---------STQTKLYELDLVLMTT------------MQNFTKYKSEFLQKLSSSLRMVVTVFNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNV-LSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHL--HGDQ--EPDNPISINNRKRKYETINRNHQALAFQLISDSLESTD-----GIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSG---------------ANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYF---VKKTTALIEAVKLDS------------KEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
NG CV+ +RC+C G+ GE CE ++N+C+ NPC N CI N + C C F G CQ + + C + C+NGG C + + C C+ G+IG C ++++C REL C N G C + + C C PGY G +C + GC S C NGGVC + P C+C ++ GK C K L+++ P L D C + +CD++CNTFAC +DGGDC +PW C C VFN+ C+ CNN DCL+D DC + C + Y + CDE C + +CG+DG DC + + ++ L++L ++L T+ ++ +T+ + F ++L ++ ++ + L ++ C +CF S E+ + +L A N+ P + AR ++K + P M L+ + I VLL R K + + +W P F K P ++E + + + PKT + L H DQ +PD P ++ K E + L+SD ++ D H A + TMA +++ ++ G +G + + +A+ G ANII + S+ D G T L +AA + +L+ ++ N RS ++ F ++ ++A D + M+ L+ + VN +D G+S +HW+A NN L + + DLK +++PLFLAA EG+ ++VK LLA+F I MD P+ IA+E+ ++I L+ E
Sbjct: 1045 NGTCVDRVG-GYRCNCPPGFTGERCEGDINECLSNPCSPSNSFDCIQLPN-DYQCVCKPGFTGRRCQNKFSVCESQPCQNGGACSVSSSSPLGYTCTCQLGYIGPNCE-RSMSC-------RELSCYNGGSCTLT-SRGARCSCLPGYGGPQCQHRSTE----GCSSKPCRNGGVC-TEETSYPYFSCQCSKDWAGKRC---------------------EHKSLVLQVPTCP-LSD--CHRKANDSVCDKECNTFACRWDGGDCSLAMNPWANCTN---PMCWRVFNNSQCDEACNNEDCLYDNFDCRNKEKVCNPIYETYCLDHYADGKCDEGCFTEECGWDGMDCGGKFPEDIVDDVLVLVVLLPPDELLRTSSAFLHKLSIILRTSVRFKLDQNGKALIRPYTRREGRFKRELEPQEEVIGSI---------------VYLELDNRMCSQGSEECFPSAERAAEYLGALSAVENLRFPYPLKTAR--------AEKIQPPDVEMPTWVQLMFAGMGSLFILVLLAIGMLMTRRKREHSTLWFPE--------------GFFLKKEPSSNKNRRE-PVGQDALGMKHMPKTVEESLLGDHSDQWMDPDCP---EPKRIKVEEPS---------LLSDCEDAVDCRQWTQHHLAAADIRVPPTMALTPPQGEFESDCMDVNVRG------PDGFTPLMLASFCGGGLESEVAEEEESEECSANIISDLIYQGASLAAQTDRTGETAL--HLAARYARADAAKRLLDAGADANAQDNTGRSPLHAAVAADAQGVFQILIRNRATDLDARMYDGSTALILAARLAVEGMVEELITCHADVNSVDELGKSALHWAAAVNNVDATVALLKNGANKDMQDLK---EETPLFLAAREGSCEAVKVLLAHFANREITDHMDRL---PRDIAQERMHHDIVQLLDE 1877 HSP 2 Score: 113.235 bits (282), Expect = 1.106e-24 Identity = 110/381 (28.87%), Postives = 159/381 (41.73%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNV---------NCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI---CECKGEFTGKN-----------------CTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCN--TFAC----NYDGGDCDPWR---KCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCH-----KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDC 1354
C ++PC NG + ++C C G+ G+ CE +N+C +PC+NGGTCID + C+C +G LC+ N C N GTC G ++C C GF GE C C P +N +C PN C C PG+TG RC K + C+S C NGG C V + SP+ C C+ + G N CT+ + R L P+ + +S C + K G+C ++ + F+C ++ G C+ + L C ND VC+ ECN C +DG DC ++C C ++ N CDE CN+ C +D DC
Sbjct: 953 CEDKPCRNGATCRPYVGGYQCDCMPGFMGQNCEREINECQSHPCQNGGTCIDLV-GHYICSCPPGTLGVLCEINEDDCNTPVRPRNAPPKCLNNGTCVDRVGG-YRCNCPPGFTGERCEGDINECLSNPCSP----SNSFDCIQLPN-DYQCVCKPGFTGRRCQNKFSV-----CESQPCQNGGACSV-SSSSPLGYTCTCQLGYIGPNCERSMSCRELSCYNGGSCTLTSRGARCSCLPGYGGPQC---------QHRSTEGCSS--KPCRNGGVCTEETSYPYFSCQCSKDWAGKRCEHKSLVLQVPTCPLSDCHRKANDSVCDKECNTFACRWDGGDCSLAMNPWANCTNPMCWRVFNNSQCDEACNNEDCLYDNFDC 1309 HSP 3 Score: 112.079 bits (279), Expect = 2.621e-24 Identity = 78/203 (38.42%), Postives = 101/203 (49.75%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENP-CLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
C PC++G C + + + CSC G+ G C +N+C NPCKNGGTC D NS +TC C F G C+ P C +C NGGTC NG + C CR GF G C + C P +C + E + C C GYTG+RC + PV+ +S C NGG C+ D S CECK ++G C IP
Sbjct: 714 CVPNPCLSGGSCTDGVN-SYHCSCLPGFTGSRCALEINECQSNPCKNGGTCTDYVNS-YTCTCRPGFTGIHCEINIPDCTESSCFNGGTCTDKING-YSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLE-------SFRCTCPKGYTGNRC----QTPVDWCRRSSPCQNGGRCRQND-ASFTCECKNGWSGHYCDIP 901 HSP 4 Score: 107.071 bits (266), Expect = 1.027e-22 Identity = 76/201 (37.81%), Postives = 98/201 (48.76%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PCV+G C E + +RC C GW G+ C+ + NDC+ +PC+N GTCIDK N FTC C FIGNLCQ N C + C N GTC F C C + G CA C P C NH C + + C C PG+ G C+ +++ C S+ C N G C G +C C+ FTG C
Sbjct: 523 CGSSPCVHGSCREDIN-GYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNG-FTCKCRQGFIGNLCQVNINECASNPCLNKGTCVD-GVASFTCVCELPYSGPTCAEVLTPCSPNP------CANHAVCTHTADYLGYQCNCQPGWQGQLCN------IDVNECISNPCKNRGTCTNTLGGF-VCSCRAGFTGLTC 707 HSP 5 Score: 83.1889 bits (204), Expect = 1.845e-15 Identity = 69/214 (32.24%), Postives = 97/214 (45.33%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNV--NCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
V + C+ C+NG C + D + C+C G++G CE+NV+DC + C NGG C+D N+ + C C ++ G C + N CL C NGGTC + G C C G+ G+ C+ I +C N C + FC+C G TG C ++ C S+ C G VC NG IC C F G C + E
Sbjct: 20 VPTLPCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNGGLCVDGVNT-YNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGG-HTCVCVNGWTGDDCSEN------IDDCATAVCFNGATCHDR-VASFFCECPVGKTGLLCH------LDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDE 218 HSP 6 Score: 82.8037 bits (203), Expect = 2.542e-15 Identity = 66/185 (35.68%), Postives = 91/185 (49.19%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNG 889
C++ PC NG F C C G++G CE N+N+C +PC + GTCID S +TCNC + G C+ + N C + C+N G C L N + C+C++G G C + C P ++G C N C C PG+TG +C+ VEI C S C NGG C +NG
Sbjct: 335 CASTPCQNGAKCHDRPNGFECRCAEGYEGTLCESNINNCQPDPCHH-GTCIDGIAS-YTCNCDPGYTGYRCENQLNECHSNPCQNSGKCVDLVN-KYICQCQHGTSGTNCEINFDDCASNPC-------DYGICKDGINR-YDCVCKPGFTGPKCN------VEIDECASSPCRNGGTCVDEENG 502 HSP 7 Score: 53.9138 bits (128), Expect = 1.556e-6 Identity = 45/143 (31.47%), Postives = 59/143 (41.26%), Query Frame = 2
Query: 512 FTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCT 937
F C C + G +C+ PC C NGGTC + ++C C GF G C CP C N G C N T C+C P +TG C + E + + C NGG C G C C +TG +C+
Sbjct: 5 FRCQCQPGYSGRICEVPTLPCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCP------GHKCMNGGLCVDGVN-TYNCQCPPEWTGQYCAEDVN---ECLMQPNACHNGGTCFNTIGGH-TCVCVNGWTGDDCS 136
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:101162450]) HSP 1 Score: 182.956 bits (463), Expect = 5.532e-46 Identity = 235/940 (25.00%), Postives = 380/940 (40.43%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCK--NGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGM--FQCKCRYGFIGEFCAVQNIACPVIPKKKREL-CNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKC---------STQTKLYELDLVLMTT------------MQNFTKYKSEFLQKLSSSLRMVVTVFNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNV-LSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHL--HGDQ--EPDNPISINNRKRKYETINRNHQALAFQLISDSLESTD-----GIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSG---------------ANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYF---VKKTTALIEAVKLDS------------KEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSI--KMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
NG CV+ +RC+C G+ GE CE ++N+C+ NPC N CI N + C C F G CQ + + C + C+NGG C + + C C+ G+IG C ++++C REL C N G C + + C C PGY G +C + GC S C NGGVC + P C+C ++ GK C K L+++ P L D C + +CD++CNTFAC +DGGDC +PW C C VFN+ C+ CNN DCL+D DC + C + Y + CDE C + +CG+DG DC + + ++ L++L ++L T+ ++ +T+ + F ++L ++ ++ + L ++ C +CF S E+ + +L A N+ P + AR ++K + P M L+ + I VLL R K + + +W P F K P ++E + + + PKT + L H DQ +PD P ++ K E + L+SD ++ D H A + TMA +++ ++ G +G + + +A+ G ANII + S+ D G T L +AA + +L+ ++ N RS ++ F ++ ++A D + M+ L+ + VN +D G+S +HW+A NN L + + DLK +++PLFLAA EG+ ++VK LLA+F I MD P+ IA+E+ ++I L+ E
Sbjct: 1168 NGTCVDRVG-GYRCNCPPGFTGERCEGDINECLSNPCSPSNSFDCIQLPN-DYQCVCKPGFTGRRCQNKFSVCESQPCQNGGACSVSSSSPLGYTCTCQLGYIGPNCE-RSMSC-------RELSCYNGGSCTLT-SRGARCSCLPGYGGPQCQHRSTE----GCSSKPCRNGGVC-TEETSYPYFSCQCSKDWAGKRC---------------------EHKSLVLQVPTCP-LSD--CHRKANDSVCDKECNTFACRWDGGDCSLAMNPWANCTN---PMCWRVFNNSQCDEACNNEDCLYDNFDCRNKEKVCNPIYETYCLDHYADGKCDEGCFTEECGWDGMDCGGKFPEDIVDDVLVLVVLLPPDELLRTSSAFLHKLSIILRTSVRFKLDQNGKALIRPYTRREGRFKRELEPQEEVIGSI---------------VYLELDNRMCSQGSEECFPSAERAAEYLGALSAVENLRFPYPLKTAR--------AEKIQPPDVEMPTWVQLMFAGMGSLFILVLLAIGMLMTRRKREHSTLWFPE--------------GFFLKKEPSSNKNRRE-PVGQDALGMKHMPKTVEESLLGDHSDQWMDPDCP---EPKRIKVEEPS---------LLSDCEDAVDCRQWTQHHLAAADIRVPPTMALTPPQGEFESDCMDVNVRG------PDGFTPLMLASFCGGGLESEVAEEEESEECSANIISDLIYQGASLAAQTDRTGETAL--HLAARYARADAAKRLLDAGADANAQDNTGRSPLHAAVAADAQGVFQILIRNRATDLDARMYDGSTALILAARLAVEGMVEELITCHADVNSVDELGKSALHWAAAVNNVDATVALLKNGANKDMQDLK---EETPLFLAAREGSCEAVKVLLAHFANREITDHMDRL---PRDIAQERMHHDIVQLLDE 2000 HSP 2 Score: 113.235 bits (282), Expect = 1.295e-24 Identity = 110/381 (28.87%), Postives = 159/381 (41.73%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNV---------NCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI---CECKGEFTGKN-----------------CTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCN--TFAC----NYDGGDCDPWR---KCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCH-----KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDC 1354
C ++PC NG + ++C C G+ G+ CE +N+C +PC+NGGTCID + C+C +G LC+ N C N GTC G ++C C GF GE C C P +N +C PN C C PG+TG RC K + C+S C NGG C V + SP+ C C+ + G N CT+ + R L P+ + +S C + K G+C ++ + F+C ++ G C+ + L C ND VC+ ECN C +DG DC ++C C ++ N CDE CN+ C +D DC
Sbjct: 1076 CEDKPCRNGATCRPYVGGYQCDCMPGFMGQNCEREINECQSHPCQNGGTCIDLV-GHYICSCPPGTLGVLCEINEDDCNTPVRPRNAPPKCLNNGTCVDRVGG-YRCNCPPGFTGERCEGDINECLSNPCSP----SNSFDCIQLPN-DYQCVCKPGFTGRRCQNKFSV-----CESQPCQNGGACSV-SSSSPLGYTCTCQLGYIGPNCERSMSCRELSCYNGGSCTLTSRGARCSCLPGYGGPQC---------QHRSTEGCSS--KPCRNGGVCTEETSYPYFSCQCSKDWAGKRCEHKSLVLQVPTCPLSDCHRKANDSVCDKECNTFACRWDGGDCSLAMNPWANCTNPMCWRVFNNSQCDEACNNEDCLYDNFDC 1432 HSP 3 Score: 112.079 bits (279), Expect = 3.015e-24 Identity = 78/203 (38.42%), Postives = 101/203 (49.75%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENP-CLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIP 943
C PC++G C + + + CSC G+ G C +N+C NPCKNGGTC D NS +TC C F G C+ P C +C NGGTC NG + C CR GF G C + C P +C + E + C C GYTG+RC + PV+ +S C NGG C+ D S CECK ++G C IP
Sbjct: 837 CVPNPCLSGGSCTDGVN-SYHCSCLPGFTGSRCALEINECQSNPCKNGGTCTDYVNS-YTCTCRPGFTGIHCEINIPDCTESSCFNGGTCTDKING-YSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLE-------SFRCTCPKGYTGNRC----QTPVDWCRRSSPCQNGGRCRQND-ASFTCECKNGWSGHYCDIP 1024 HSP 4 Score: 106.686 bits (265), Expect = 1.201e-22 Identity = 76/201 (37.81%), Postives = 98/201 (48.76%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
C + PCV+G C E + +RC C GW G+ C+ + NDC+ +PC+N GTCIDK N FTC C FIGNLCQ N C + C N GTC F C C + G CA C P C NH C + + C C PG+ G C+ +++ C S+ C N G C G +C C+ FTG C
Sbjct: 646 CGSSPCVHGSCREDIN-GYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNG-FTCKCRQGFIGNLCQVNINECASNPCLNKGTCVD-GVASFTCVCELPYSGPTCAEVLTPCSPNP------CANHAVCTHTADYLGYQCNCQPGWQGQLCN------IDVNECISNPCKNRGTCTNTLGGF-VCSCRAGFTGLTC 830 HSP 5 Score: 84.3445 bits (207), Expect = 8.492e-16 Identity = 66/214 (30.84%), Postives = 95/214 (44.39%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQ-NPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFEN-PCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C+ PC NG ++ ++ CSC G++G+ C ++N+C + C N G CI+ K S F C C + G +C+ PC C NGGTC + ++C C GF G C CP C N G C N T C+C P +TG C + E + + C NGG C G C C +TG +C+ + + N
Sbjct: 71 CATSPCANGARCVNWNDQYNCSCPPGFQGKNCHNDINECRKPGVCLNNGLCINMKGS-FRCQCQPGYSGRICEVPTLPCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCP------GHKCMNGGLCVDGVN-TYNCQCPPEWTGQYCAEDVN---ECLMQPNACHNGGTCFNTIGGH-TCVCVNGWTGDDCSENIDDCATAVCFN 272 HSP 6 Score: 82.8037 bits (203), Expect = 2.222e-15 Identity = 69/214 (32.24%), Postives = 97/214 (45.33%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNV--NCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
V + C+ C+NG C + D + C+C G++G CE+NV+DC + C NGG C+D N+ + C C ++ G C + N CL C NGGTC + G C C G+ G+ C+ I +C N C + FC+C G TG C ++ C S+ C G VC NG IC C F G C + E
Sbjct: 143 VPTLPCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNGGLCVDGVNT-YNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFNTIGG-HTCVCVNGWTGDDCSEN------IDDCATAVCFNGATCHDR-VASFFCECPVGKTGLLCH------LDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDE 341 HSP 7 Score: 82.4185 bits (202), Expect = 3.167e-15 Identity = 66/185 (35.68%), Postives = 91/185 (49.19%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIG-CKSDYCFNGGVCKVLDNG 889
C++ PC NG F C C G++G CE N+N+C +PC + GTCID S +TCNC + G C+ + N C + C+N G C L N + C+C++G G C + C P ++G C N C C PG+TG +C+ VEI C S C NGG C +NG
Sbjct: 458 CASTPCQNGAKCHDRPNGFECRCAEGYEGTLCESNINNCQPDPCHH-GTCIDGIAS-YTCNCDPGYTGYRCENQLNECHSNPCQNSGKCVDLVN-KYICQCQHGTSGTNCEINFDDCASNPC-------DYGICKDGINR-YDCVCKPGFTGPKCN------VEIDECASSPCRNGGTCVDEENG 625 HSP 8 Score: 70.4774 bits (171), Expect = 1.434e-11 Identity = 54/171 (31.58%), Postives = 82/171 (47.95%), Query Frame = 2
Query: 446 VNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVN-CENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
++ C +PC NG C++ N Q+ C+C F G C + N C C N G C +++ G F+C+C+ G+ G C V + P P + C N G C + + C C PG+ G C+K + C C NGG+C V + C+C E+TG+ C + E
Sbjct: 68 IDACATSPCANGARCVN-WNDQYNCSCPPGFQGKNCHNDINECRKPGVCLNNGLCINMK-GSFRCQCQPGYSGRICEVPTL--PCAPSQ----CLNGGTCRQTSDHSYECACLPGFEGHNCEKNVD-----DCPGHKCMNGGLC-VDGVNTYNCQCPPEWTGQYCAEDVNE 224
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Match: notch1a (neurogenic locus notch homolog protein 1 [Source:NCBI gene;Acc:101171596]) HSP 1 Score: 176.407 bits (446), Expect = 6.567e-44 Identity = 229/955 (23.98%), Postives = 371/955 (38.85%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGT--CIDKKNSQFTCNCTSQFIGNLC-QFENPCLNVNCENGGTCESLENG--MFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNE---------GLTKCSTQTKLYELDLVLMTTM-------------------QNFTKYK----------------SEFLQKLSSSLRMVVTVFNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTD----GIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSM------------LHS-LDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYF---VKKTTALIEAVKLDSKEMISL------------LLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLA--DLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
NG+CV+ ++C C G+ GE CE +VN+C+ +PC G+ CI NS + C C + + G C + + C C NGGTC N F CKC GF G C + +C + C N G C + ++ C C +TG C E P + C S+ C+NGG C+ N +P C C F G C I L + P E I + C N ICD CN AC +DGGDC DPW+ C C FNDG C+ +CN+ CL+DG DC + + C + Y + CD+ CN+ +C +DG DC + + K + + L EL VL T + Q+ K+ + L ++ S+ VVT E++ ++ L ++ QC +CF S ++ FL A G+ L +P+ A R S + P+Y + L L + +GVL+ K + ++ W G+ P + ++ E + K + D +++ GD +PD R+Y L Q + D + TD +DA + ++A + + ++ G +G + + IA+ G +PS+ LH+ D G T L +AA S +LE + N R+ ++ F ++ ++A D + L L++ + N D G+S +HW+A + + + + + A D++DN++++PLFLAA EG+ ++ K LL +F I + P+ IA+E+ ++I L+ E
Sbjct: 1152 NGRCVDRIG-GYQCMCPPGYVGERCEGDVNECLSDPCDPRGSYNCIQLMNS-YRCECRTGYTGQRCDKVFDGCKGRPCRNGGTCAVASNTPHGFICKCPPGFTGSSCEYDSHSCGSL------NCKNGGTC-VSGHLGPRCLCPSAFTGPEC----ETPTDSLCISNPCYNGGTCQTTPN-APFFKCSCPSNFNGLLCHI-LDYSFVGGFGRDITPPPEVEVSCGIPQ----------CDEWAGNHICDSLCNNHACGWDGGDCSLNFDDPWKNCSA--ALQCWRYFNDGKCDGQCNSPGCLYDGFDCQGQEGQCNPLYDQYCKDHYADGHCDQGCNNAECEWDGLDCANNMPEKLADGHLVLVVHIPPEVLKNRSSSFLRELSSVLHTNVVFRRDAKGEPMIFPYYGNEQDLVKHSMLKRSADGWPEWASVPANVLDQMKESVSSVVTSRRRRELDPVQVKGSIVYLEIDNRQCYQQSSECFQSATDVAAFLGALASSGH-LKVPYIEAVTSVR-PPGSTSELYPMYII----FLGLAALGFICLGVLVSRKRRREHGQL-----W------------FPEGFKVSEPSKKKRREPLGEDSVGLKPMKNSDINLMDDNQNEWGDDDPD--------CRRYR--------LEEQAMLDLCDHTDQRKWTQQHLDAADLRIASIAPTPPQGEIENDCMDVNVRG------PDGFTPLMIASCSGGGLETGNSEEEEDPSVEIISDFIYQGANLHNQTDRTGETAL--HLAARYARSDAAKRLLESSADANVQDNMGRTPLHAAVAADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMAEELINSHADPNATDDSGKSALHWAAA-----VNNVEAALVLLKNGANKDMQDNKEETPLFLAAREGSYETAKVLLDHFANREITDHLD-QLPRDIAQERMHHDIVRLLDE 2026 HSP 2 Score: 102.449 bits (254), Expect = 2.418e-21 Identity = 87/286 (30.42%), Postives = 127/286 (44.41%), Query Frame = 2
Query: 341 CSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE------NPCLN---------------------VNCE------------NGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKK----RELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKE------LPVEIG---------CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIK 1021
C + PC NG C + + + C+C G+ G CE N NDC + C NGGTC+D NS FTC C + F G+ CQF+ PCLN VNC+ NGGTC + + C+C+ G+ G +C + +++C V K++ +LC N G+C + T C+C GYTG C ++ + +P G C+S C NGG C L N + C C G +C + L + PK FN + + +
Sbjct: 878 CESNPCKNGANCTDCVN-SYTCTCPTGFSGINCEINTNDCTDSSCFNGGTCVDGINS-FTCLCLTGFTGSYCQFDINECDSKPCLNGGTCLDGYGTYKCTCPHGYTGVNCQHLVRWCDSSPCKNGGTCWQ-QGASYTCQCQTGWTGLYCDIPSVSCEVAAKQQGVEVNQLCRNSGQC-LDAGSTHHCRCQAGYTGSYCQEQVDERILSCVPGYHGVNCSKEINECQSQPCQNGGTCIDLIN-TYKCSCPRGTQGVHCEMNLDDCNPFNDPFTNEPKCFNNGRCVDR 1158 HSP 3 Score: 102.064 bits (253), Expect = 3.391e-21 Identity = 112/351 (31.91%), Postives = 148/351 (42.17%), Query Frame = 2
Query: 404 SCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ--------FENPCLN-VNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGIC----DQQCNTFACNYDGGDCD-----PWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFD-------GEDCH-----KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDC 1354
SC G+ G C + +N+C PC+NGGTCID N+ + C+C G C+ F +P N C N G C G +QC C G++GE C C P C+ G + M + C+C GYTG RCDK V GCK C NGG C V N +P IC+C FTG +C ++ +N K T L + LC ++F C D C + C Y+GG C P+ KC C FN +C+ + D G D + SC +C E N ICD CN+ CG+DGGDC
Sbjct: 1081 SCVPGYHGVNCSKEINECQSQPCQNGGTCIDLINT-YKCSCPRGTQGVHCEMNLDDCNPFNDPFTNEPKCFNNGRCVDRIGG-YQCMCPPGYVGERCEGDVNECLSDP------CDPRGSYNCIQLMNSYRCECRTGYTGQRCDK-----VFDGCKGRPCRNGGTCAVASN-TPHGFICKCPPGFTGSSCEY---DSHSCGSLNCKNGGTCVSGHLGPRC---------LCPSAFTGPECETPTDSLCISNPC-YNGGTCQTTPNAPFFKC------SCPSNFNGLLCH--------ILDYSFVGGFGRDITPPPEVEVSCGIPQCDEWAGNHICDSLCNNHACGWDGGDC 1390 HSP 4 Score: 100.908 bits (250), Expect = 7.758e-21 Identity = 72/214 (33.64%), Postives = 103/214 (48.13%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC+NG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ + N C+ C NG C + G +QCKC+ GF G+ C I K C+N G C + ++ F C C PG+ G RC++ C+S+ C NG C N S C C F+G NC I + + N
Sbjct: 726 CDSNPCMNGGTCKDMTSGYHCTCRVGFTGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCLLPYTGQTCEIDINECVKSPCWNGAFCLNTMGG-YQCKCQPGFTGQKCETD------IDDCKPNPCSNGGLC--HDGISSFTCTCLPGFRGGRCEQDINE-----CESNPCKNGANCTDCVN-SYTCTCPTGFSGINCEINTNDCTDSSCFN 923 HSP 5 Score: 92.8189 bits (229), Expect = 2.186e-18 Identity = 76/249 (30.52%), Postives = 106/249 (42.57%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC------------DIYPNMTLF------------------------CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC G C + F C C G+ G CE N+N+C+ PCKNGGTC D++NS + C+C G C+ + C + C+ G C NG ++C CR G+ G C + C + P C+N G C + Y + T C CD G++G CD K C S+ C NGG CK + +G C C+ FTG NC + E +N
Sbjct: 539 CYSDPCHYGTCKDGL-ASFTCYCRPGYTGRLCETNINECLSQPCKNGGTCQDRENS-YICSCPKGTAGFNCEINLDDCKSQPCDY-GRCIDKING-YECACRPGYTGTMCNINIDDCAINP------CHNGGTCIDGINSFTCLCPEGYNDATCLSQVDECSSNPCIHGLCQDLINGYKCTCDSGWSGQNCDINKNE-----CDSNPCMNGGTCKDMTSGY-HCTCRVGFTGPNCQTNINECASNPCLN 771 HSP 6 Score: 92.0485 bits (227), Expect = 3.816e-18 Identity = 80/265 (30.19%), Postives = 114/265 (43.02%), Query Frame = 2
Query: 341 CSNRPCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC-DIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLC-----DNLCKASFENGICDQQCNTFAC 1111
C + PC N C++ F C C G++G C + ++C PC N G CIDK NS F C C F GNLCQ + + C + C NG C N + C+C G+ G+ C + C P ++G C D + T +C+ PGYTG C+ C S C NGG C+ +N S IC C G NC I L + + + + N + + + ++C D G C N+F C
Sbjct: 425 CMSNPCQNDATCLDQIG-GFHCICMPGYEGVFCHIDTDECASQPCLNNGKCIDKINS-FYCECPKGFSGNLCQVDIDECASTPCRNGAKCTDGPN-KYNCECAEGYTGQHCEIDINECYSDPC-------HYGTCKDGLASFTCYCR--PGYTGRLCETNINE-----CLSQPCKNGGTCQDREN-SYICSCPKGTAGFNCEINLDDCKSQPCDYGRCIDKINGYECACRPGYTGTMCNINIDDCAINPCHNGGTCIDGINSFTC 671 HSP 7 Score: 87.8113 bits (216), Expect = 6.290e-17 Identity = 67/241 (27.80%), Postives = 103/241 (42.74%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQ----------------------------------------NPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C++ PC NG + D +RC+C + G+TC+ +VN+C Q +PC+NGGTC+ K ++ + C+C F+G C+ + C NC+NGG C N + C+C + G++C C ++P +C N G C + + C C G+TGD C K + C + CF+G C S CEC TG C +
Sbjct: 113 CASNPCANGGQCSSLDSTYRCTCPPNFHGQTCKLDVNECAQTPYLCLNGGICVNEVGSYHCRCPQEYTGQHCQTPYVPCSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHCEHNIDDCPGHNCQNGGVCADGVN-TYNCQCPPHYTGQYCTENVDECEMMPN----VCQNGGTCHDT-HGSYHCVCVNGWTGDDCSKNID-----DCAAAACFHGATCHDR-VASFFCECPHGRTGLLCHL 341 HSP 8 Score: 86.6557 bits (213), Expect = 1.356e-16 Identity = 66/209 (31.58%), Postives = 94/209 (44.98%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF---ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
CS PC NG CV+ D + CSC G+ G+ CE N++DC + C+NGG C D N+ + C C + G C E + C+NGGTC +G + C C G+ G+ C+ C C++ + FC+C G TG C ++ C S+ C G C NG IC C +TG C + + E
Sbjct: 191 CSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHCEHNIDDCPGHNCQNGGVCADGVNT-YNCQCPPHYTGQYCTENVDECEMMPNVCQNGGTCHDT-HGSYHCVCVNGWTGDDCSKNIDDCAAAACFHGATCHDR-------VASFFCECPHGRTGLLCH------LDDACISNPCQKGSNCDTNPVNGKAICTCPPGYTGSACNLDIDE 384 HSP 9 Score: 83.5741 bits (205), Expect = 1.217e-15 Identity = 66/203 (32.51%), Postives = 87/203 (42.86%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDP----EFRCSCWHGWKGETCEENVND-CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
CS PC NG A +F C C G+ C N C+ PC+NGGTC + F C C + G CQ NPC + C NGG C SL++ ++C C F G+ C + C P LC N G C + + C+C YTG C + C C NGG C + + C C F G++C
Sbjct: 32 CSPSPCRNGGRCRAVSRGNTFDFLCECPLGFTDRLCLTPTNHACMSAPCRNGGTCELIALTDFRCQCPPGWTGKSCQTPNPCASNPCANGGQCSSLDS-TYRCTCPPNFHGQTCKLDVNECAQTPY----LCLNGGIC-VNEVGSYHCRCPQEYTGQHCQTPY-----VPCSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHC 223 HSP 10 Score: 78.1814 bits (191), Expect = 6.152e-14 Identity = 53/164 (32.32%), Postives = 72/164 (43.90%), Query Frame = 2
Query: 524 CTSQFIGNLCQFENPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAV-QNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNE 1003
C S +IGN CQ+ +PC C NGG C ++ G F C+C GF C N AC P C N G C++ C+C PG+TG C C S+ C NGG C LD+ + C C F G+ C + + E + + + NE
Sbjct: 17 CPSDYIGNRCQYPSPCSPSPCRNGGRCRAVSRGNTFDFLCECPLGFTDRLCLTPTNHACMSAP------CRNGGTCELIALTDFRCQCPPGWTGKSCQTPNP------CASNPCANGGQCSSLDS-TYRCTCPPNFHGQTCKLDVNECAQTPYLCLNGGICVNE 167
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Match: notch1a (neurogenic locus notch homolog protein 1 [Source:NCBI gene;Acc:101171596]) HSP 1 Score: 175.252 bits (443), Expect = 1.342e-43 Identity = 229/955 (23.98%), Postives = 371/955 (38.85%), Query Frame = 2
Query: 362 NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGT--CIDKKNSQFTCNCTSQFIGNLC-QFENPCLNVNCENGGTCESLENG--MFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPI--CECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDC-----DPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHK-----CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNE---------GLTKCSTQTKLYELDLVLMTTM-------------------QNFTKYK----------------SEFLQKLSSSLRMVVTVFNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTD----GIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSM------------LHS-LDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYF---VKKTTALIEAVKLDSKEMISL------------LLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLA--DLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLIQE 2941
NG+CV+ ++C C G+ GE CE +VN+C+ +PC G+ CI NS + C C + + G C + + C C NGGTC N F CKC GF G C + +C + C N G C + ++ C C +TG C E P + C S+ C+NGG C+ N +P C C F G C I L + P E I + C N ICD CN AC +DGGDC DPW+ C C FNDG C+ +CN+ CL+DG DC + + C + Y + CD+ CN+ +C +DG DC + + K + + L EL VL T + Q+ K+ + L ++ S+ VVT E++ ++ L ++ QC +CF S ++ FL A G+ L +P+ A R S + P+Y + L L + +GVL+ K + ++ W G+ P + ++ E + K + D +++ GD +PD R+Y L Q + D + TD +DA + ++A + + ++ G +G + + IA+ G +PS+ LH+ D G T L +AA S +LE + N R+ ++ F ++ ++A D + L L++ + N D G+S +HW+A + + + + + A D++DN++++PLFLAA EG+ ++ K LL +F I + P+ IA+E+ ++I L+ E
Sbjct: 1241 NGRCVDRIG-GYQCMCPPGYVGERCEGDVNECLSDPCDPRGSYNCIQLMNS-YRCECRTGYTGQRCDKVFDGCKGRPCRNGGTCAVASNTPHGFICKCPPGFTGSSCEYDSHSCGSL------NCKNGGTC-VSGHLGPRCLCPSAFTGPEC----ETPTDSLCISNPCYNGGTCQTTPN-APFFKCSCPSNFNGLLCHI-LDYSFVGGFGRDITPPPEVEVSCGIPQ----------CDEWAGNHICDSLCNNHACGWDGGDCSLNFDDPWKNCSA--ALQCWRYFNDGKCDGQCNSPGCLYDGFDCQGQEGQCNPLYDQYCKDHYADGHCDQGCNNAECEWDGLDCANNMPEKLADGHLVLVVHIPPEVLKNRSSSFLRELSSVLHTNVVFRRDAKGEPMIFPYYGNEQDLVKHSMLKRSADGWPEWASVPANVLDQMKESVSSVVTSRRRRELDPVQVKGSIVYLEIDNRQCYQQSSECFQSATDVAAFLGALASSGH-LKVPYIEAVTSVR-PPGSTSELYPMYII----FLGLAALGFICLGVLVSRKRRREHGQL-----W------------FPEGFKVSEPSKKKRREPLGEDSVGLKPMKNSDINLMDDNQNEWGDDDPD--------CRRYR--------LEEQAMLDLCDHTDQRKWTQQHLDAADLRIASIAPTPPQGEIENDCMDVNVRG------PDGFTPLMIASCSGGGLETGNSEEEEDPSVEIISDFIYQGANLHNQTDRTGETAL--HLAARYARSDAAKRLLESSADANVQDNMGRTPLHAAVAADAQGVFQILIRNRATDLDARMHDGTTPLILAARLAVEGMAEELINSHADPNATDDSGKSALHWAAA-----VNNVEAALVLLKNGANKDMQDNKEETPLFLAAREGSYETAKVLLDHFANREITDHLD-QLPRDIAQERMHHDIVRLLDE 2115 HSP 2 Score: 110.923 bits (276), Expect = 6.478e-24 Identity = 118/372 (31.72%), Postives = 156/372 (41.94%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ--------FENPCLN-VNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSP---ICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGIC----DQQCNTFACNYDGGDCD-----PWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFD-------GEDCH-----KSSCKFHKCSELYQNKICDEECNSPQCGFDGGDC 1354
CS PC NG + + C C G+ G C + +N+C PC+NGGTCID N+ + C+C G C+ F +P N C N G C G +QC C G++GE C C P C+ G + M + C+C GYTG RCDK V GCK C NGG C V N +P IC+C FTG +C ++ +N K T L + LC ++F C D C + C Y+GG C P+ KC C FN +C+ + D G D + SC +C E N ICD CN+ CG+DGGDC
Sbjct: 1149 CSPNPCQNGATCTDYLGGYSCECVPGYHGVNCSKEINECQSQPCQNGGTCIDLINT-YKCSCPRGTQGVHCEMNLDDCNPFNDPFTNEPKCFNNGRCVDRIGG-YQCMCPPGYVGERCEGDVNECLSDP------CDPRGSYNCIQLMNSYRCECRTGYTGQRCDK-----VFDGCKGRPCRNGGTCAVASN-TPHGFICKCPPGFTGSSCEY---DSHSCGSLNCKNGGTCVSGHLGPRC---------LCPSAFTGPECETPTDSLCISNPC-YNGGTCQTTPNAPFFKC------SCPSNFNGLLCH--------ILDYSFVGGFGRDITPPPEVEVSCGIPQCDEWAGNHICDSLCNNHACGWDGGDC 1479 HSP 3 Score: 93.5893 bits (231), Expect = 1.327e-18 Identity = 69/215 (32.09%), Postives = 97/215 (45.12%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC+NG + + C+C G+ G C+ N+N+C NPC N GTCID + + CNC + G C+ PC + C+NGG C+ E+ F C C G+ G+ C + C P C N M + CKC PG+TG +C+ + CK + C NGG+C S C C F G C + E N
Sbjct: 757 CDSNPCMNGGTCKDMTSGYHCTCRVGFTGPNCQTNINECASNPCLNQGTCIDDV-AGYKCNCLLPYTGENCETLLAPCSSRPCKNGGVCKEAEDYQSFSCICPEGWQGQTCEIDINECVKSPCWNGAFCLN--------TMGGYQCKCQPGFTGQKCETDID-----DCKPNPCSNGGLCHD-GISSFTCTCLPGFRGGRCEQDINECESNPCKN 956 HSP 4 Score: 92.0485 bits (227), Expect = 3.218e-18 Identity = 76/249 (30.52%), Postives = 106/249 (42.57%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC------------DIYPNMTLF------------------------CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C + PC G C + F C C G+ G CE N+N+C+ PCKNGGTC D++NS + C+C G C+ + C + C+ G C NG ++C CR G+ G C + C + P C+N G C + Y + T C CD G++G CD K C S+ C NGG CK + +G C C+ FTG NC + E +N
Sbjct: 570 CYSDPCHYGTCKDGL-ASFTCYCRPGYTGRLCETNINECLSQPCKNGGTCQDRENS-YICSCPKGTAGFNCEINLDDCKSQPCDY-GRCIDKING-YECACRPGYTGTMCNINIDDCAINP------CHNGGTCIDGINSFTCLCPEGYNDATCLSQVDECSSNPCIHGLCQDLINGYKCTCDSGWSGQNCDINKNE-----CDSNPCMNGGTCKDMTSGY-HCTCRVGFTGPNCQTNINECASNPCLN 802 HSP 5 Score: 89.3521 bits (220), Expect = 2.300e-17 Identity = 59/182 (32.42%), Postives = 80/182 (43.96%), Query Frame = 2
Query: 470 CKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAV-QNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNE 1003
C NGG C+ + C C S +IGN CQ+ +PC C NGG C ++ G F C+C GF C N AC P C N G C++ C+C PG+TG C C S+ C NGG C LD+ + C C F G+ C + + E + + + NE
Sbjct: 30 CLNGGRCVATSSGNGECRCPSDYIGNRCQYPSPCSPSPCRNGGRCRAVSRGNTFDFLCECPLGFTDRLCLTPTNHACMSAP------CRNGGTCELIALTDFRCQCPPGWTGKSCQTPNP------CASNPCANGGQCSSLDS-TYRCTCPPNFHGQTCKLDVNECAQTPYLCLNGGICVNE 198 HSP 6 Score: 87.0409 bits (214), Expect = 1.033e-16 Identity = 67/241 (27.80%), Postives = 103/241 (42.74%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQ----------------------------------------NPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C++ PC NG + D +RC+C + G+TC+ +VN+C Q +PC+NGGTC+ K ++ + C+C F+G C+ + C NC+NGG C N + C+C + G++C C ++P +C N G C + + C C G+TGD C K + C + CF+G C S CEC TG C +
Sbjct: 144 CASNPCANGGQCSSLDSTYRCTCPPNFHGQTCKLDVNECAQTPYLCLNGGICVNEVGSYHCRCPQEYTGQHCQTPYVPCSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHCEHNIDDCPGHNCQNGGVCADGVN-TYNCQCPPHYTGQYCTENVDECEMMPN----VCQNGGTCHDT-HGSYHCVCVNGWTGDDCSKNID-----DCAAAACFHGATCHDR-VASFFCECPHGRTGLLCHL 372 HSP 7 Score: 86.2705 bits (212), Expect = 2.189e-16 Identity = 66/209 (31.58%), Postives = 94/209 (44.98%), Query Frame = 2
Query: 341 CSNRPCVNG-KCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF---ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLD-NGSPICECKGEFTGKNCTIPLKE 952
CS PC NG CV+ D + CSC G+ G+ CE N++DC + C+NGG C D N+ + C C + G C E + C+NGGTC +G + C C G+ G+ C+ C C++ + FC+C G TG C ++ C S+ C G C NG IC C +TG C + + E
Sbjct: 222 CSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHCEHNIDDCPGHNCQNGGVCADGVNT-YNCQCPPHYTGQYCTENVDECEMMPNVCQNGGTCHDT-HGSYHCVCVNGWTGDDCSKNIDDCAAAACFHGATCHDR-------VASFFCECPHGRTGLLCH------LDDACISNPCQKGSNCDTNPVNGKAICTCPPGYTGSACNLDIDE 415 HSP 8 Score: 82.8037 bits (203), Expect = 2.066e-15 Identity = 66/203 (32.51%), Postives = 87/203 (42.86%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDP----EFRCSCWHGWKGETCEENVND-CIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
CS PC NG A +F C C G+ C N C+ PC+NGGTC + F C C + G CQ NPC + C NGG C SL++ ++C C F G+ C + C P LC N G C + + C+C YTG C + C C NGG C + + C C F G++C
Sbjct: 63 CSPSPCRNGGRCRAVSRGNTFDFLCECPLGFTDRLCLTPTNHACMSAPCRNGGTCELIALTDFRCQCPPGWTGKSCQTPNPCASNPCANGGQCSSLDS-TYRCTCPPNFHGQTCKLDVNECAQTPY----LCLNGGIC-VNEVGSYHCRCPQEYTGQHCQTPY-----VPCSPSPCQNGGTCVQKGDTTYDCSCLPGFMGQHC 254
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000066558.1 (SMESG000066558.1) HSP 1 Score: 2038.46 bits (5280), Expect = 0.000e+0 Identity = 1074/1087 (98.80%), Postives = 1077/1087 (99.08%), Query Frame = 2
Query: 290 MNVFILGCLLVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTVFNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMXXXXXXXXXXXXXXXXGVLLRDKWGKLRSKIKTAGVWXXXXXXXXXXXXXXXGYNFGWPKLPQLKDFKKEYQIPNKLIYGESQPKTDQHRHLHGDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKMDPNCPCPKLIAEEKGFYEIRDLIQETLRKVTITDRXXXXXXXXXXXXXXXIHNFDTSGNLCIIDEYKXXXXXXXXXXXXXXXGNESIDSCLLDLYSITDPMQNPQEPYSNEKSLYSSFKPVEHRYHGYQSNTSSSDMSPPXXXXXXXXXXXXXXSITHSEHLDSNYSNSIFLSPKSFIGLPDPINGSGLNKATDFQTDFYNYQASPILSEYKYYSNPVPKFPPVNCLL 3550
MNVFILGCL VIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASF NGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTVFNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMILAALLLLFFISITLIGVLLRDKWGKLRSKIKTAGVWTPSSGYSTSTSPINSGYNFGWPKLPQLKDFKKEYQI NKLIYGESQPKTDQH HLH DQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKE+ISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIK+DPNCPCPKLIAEEKGFYEIRDLIQETLRKVTITDRNEKKTKSKESKTKNKIHNFDTSGNLCIIDEYKELSSNSLENLQSSPLGNESIDSCLLDLYSITDPMQNPQEPYSNEKSLYSSFKPVEHRY GYQSNTSSSDMSPPLLNLNNQQFQNGFNSITHSEHLDSNYSNSIFLSPKSFIGLPDPINGSGLNK TDF DFYNYQASP LSEYKY+SNPVPKFPPVNCLL
Sbjct: 1 MNVFILGCLWVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKASFGNGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHKCSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTVFNVTEINFNFATALLIKLHVNYTQCVLYGGQCFSSLEQISNFLKAGIEKGNVLSLPFRLARVDTRIISASKKQELPIYTMILAALLLLFFISITLIGVLLRDKWGKLRSKIKTAGVWTPSSGYSTSTSPINSGYNFGWPKLPQLKDFKKEYQIQNKLIYGESQPKTDQHGHLHCDQEPDNPISINNRKRKYETINRNHQALAFQLISDSLESTDGIHPIDAGLGDVYTMASVKNHMKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEIISLLLDEGSPVNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLAYFNKSSIKIDPNCPCPKLIAEEKGFYEIRDLIQETLRKVTITDRNEKKTKSKESKTKNKIHNFDTSGNLCIIDEYKELSSNSLENLQSSPLGNESIDSCLLDLYSITDPMQNPQEPYSNEKSLYSSFKPVEHRYQGYQSNTSSSDMSPPLLNLNNQQFQNGFNSITHSEHLDSNYSNSIFLSPKSFIGLPDPINGSGLNKTTDFHADFYNYQASPTLSEYKYHSNPVPKFPPVNCLL 1087
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000063217.1 (SMESG000063217.1) HSP 1 Score: 137.117 bits (344), Expect = 4.506e-32 Identity = 141/486 (29.01%), Postives = 202/486 (41.56%), Query Frame = 2
Query: 326 VSSKLCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKN--SQFTCNCTSQFIGNLCQFE-NPC-LNVN-------------CENGGTCESLEN-GMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC------DIYPNMTLFCKCDPGYTGDRC------------------------DK---KKELPVEIG---CKSDY--------CFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCD-NLCKASFENGICDQQCNTFACNYDGGDC----------------DPWRKC--YGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKS--SCKFHK-CSELYQNKICDEECNSPQCGFDGGDCHTSRSNSFFSNEGLTKCSTQTKLYELDLVLMTTMQNFTKYKSEFLQKLSSSLRMVVTVF 1531
V++ C + C GKC++ + F C C G G CE V+ C + C+NGG C KN F CNC F G LC+ + N C N+ C GT E L+ G F C C+ F G++C + C K C N+G C ++ N C C GY G+RC D+ K E P +G C+ DY C+N G C V G IC C G+ C I L +I +T+ ++ S C+ N C + +N ICD +CN +AC +DGG+C PW C ++ C FN+ C+P+CN CLFDG DC + C C + Y + C ECN+ +C FDGGDC SR+++ L L+ ++T + +Y+++ LQ L+ L VV +
Sbjct: 983 VNTNECYSNSCNTGKCIDQIN-NFSCVCPRGVSGRFCETIVDYCKKMECQNGGIC---KNVIGDFECNCPKGFAGKLCETDINECKYNIAGNATNLISNPHGPCSPTGTLECLDRPGTFHCSCKKYFTGKYCETRIDYCEKFRKSGNIPCFNNGICLNKYQNEVGRNYNFSCICPNGYGGERCKINSKKCQLNVCKNNGICRPFEIDDRMSFKCECPPGVGGLFCEIDYVNECLSTKCYNNGSC-VNGFGKAICHCNKGSCGEKCEITGSACN---LASIDNSQTYQDE---------ISDCELNKCASKADNKICDLECNKYACGFDGGECLHRVPKRIDGNDISIASPWSNCEIIKSENIPCHNWFNNKRCDPQCNTEACLFDGWDCMDAIGQCPLQSFCDKHYADGQCQLECNTMECSFDGGDCIESRNSTIPGGIIL-------------LLPVSTTEFVARYRTKLLQSLTHLLHSVVRIM 1438 HSP 2 Score: 106.686 bits (265), Expect = 8.774e-23 Identity = 102/335 (30.45%), Postives = 140/335 (41.79%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQF-ENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDN---------LCKASFENGICD---QQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSSCKFHKCSELYQNKIC 1306
C N PC NG + FRC C G+ GE CE +N+C NPC N CID N + C C S F G C+ +N C +C G C NG F+CKC +IG C C P + C N P C C G+TG RC+ K + C+ + C + GVC+ D S C+C E+ G+ C I ET K + + F + LI K K C N C++ + C+ C + C +GG+C G + CK C P V+C + +C+ +SC KC + N C
Sbjct: 701 CRNDPCRNGATCDNLADGFRCRCVAGFTGERCEIEINECQHNPCSNDAKCIDHIN-DYQCICQSGFSGKNCEINDNDCTESSCLGHGQCVDKVNG-FECKCNENYIGTNCEHLKRPCDSNPCLNKGSCINRKVNQNTPG--YLCNCRRGFTGPRCEIKMDW-----CRGNPCGDFGVCET-DLDSFKCKCNSEYIGERCEIKKTETCKSYAV-----EKFKNESLINKICKHHGNCFNDPETGGFKCSCQSGYGGSFCEVNIDDCASQPC-INGGECGD-----GTGMYFCK-------CQPGFQGVNCQVNTNECYSNSCNTGKCIDQINNFSC 1007 HSP 3 Score: 105.145 bits (261), Expect = 2.300e-22 Identity = 103/369 (27.91%), Postives = 158/369 (42.82%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ-FENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACP--VIPKKKRELCNNHGECDIYPNM-------TLFCKCDPGYTGDRCDKKKELPVEIGCKSDY-CFNGGVC------KVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFN-EKQLIIKKTKSPSLCDNLCKASFENGICDQQCNTFACNYDGGDCDPWRKCYGNDLKHCKGVFNDGVCNPECNNVDCLFDGEDCHKSS-------------CKFHKCSELYQNKICDEECNSPQCGFDGGDC 1354
C+++PC+NG + C C G++G C+ N N+C N C N G CID+ N+ F+C C G C+ + C + C+NGG C+++ G F+C C GF G+ C C + + N HG C + T C C +TG C+ + + + + CFN G+C +V N + C C + G+ C I K+ + N I + F + ++ K P + C+ + N +C Y+ G C +G + HC N G C +C G C+ +S C+ +KC+ NKICD ECN CGFDGG+C
Sbjct: 950 CASQPCINGGECGDGTGMYFCKCQPGFQGVNCQVNTNECYSNSC-NTGKCIDQINN-FSCVCPRGVSGRFCETIVDYCKKMECQNGGICKNVI-GDFECNCPKGFAGKLCETDINECKYNIAGNATNLISNPHGPCSPTGTLECLDRPGTFHCSCKKYFTGKYCETRIDYCEKFRKSGNIPCFNNGICLNKYQNEVGRNYNFSCICPNGYGGERCKINSKKCQLNVCKNNGICRPFEIDDRMSFKCECPPGVGGLFCEIDYVNECLSTKC------YNNGSCVNG---FGKAICHC----NKGSCGEKCE-----ITGSACNLASIDNSQTYQDEISDCELNKCASKADNKICDLECNKYACGFDGGEC 1297 HSP 4 Score: 102.834 bits (255), Expect = 1.311e-21 Identity = 69/214 (32.24%), Postives = 106/214 (49.53%), Query Frame = 2
Query: 296 VFILGCLLVIVSSKLCSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNC 934
+ IL + +S C N C NG C + ++ C C +G+KG CE+ N C PC+NGGTC + C C ++++G C+F + C + C NGG C+SLE ++C+C ++G C + N P C +G+C + + + C C+ GYTGD C + ++ C NGG C + GS C+CK F G+ C
Sbjct: 9 ILILLFCPIAISLNFCENHKCKNGATCQSDINGKYVCECAYGYKGTYCEQKSN-CPITPCQNGGTC-KLIAGNYVCQCLNEWVGEFCEFSSNCASSPCRNGGICKSLEIHKYECQCPKNYLGMNCELPNSCGSQNP------CGVNGKCILANDGEVKCHCNKGYTGDTCSNDIDECASY--ETPLCENGGTC-INTVGSYQCKCKAGFNGERC 211 HSP 5 Score: 82.4185 bits (202), Expect = 2.086e-15 Identity = 92/310 (29.68%), Postives = 133/310 (42.90%), Query Frame = 2
Query: 338 LCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALINIKIPKTFNEKQLIIKKTKSPSLC---DNL--CKASFE--------NGICDQQCNTFAC----NYDGGDCD-PWRKCYGNDLKH---CKGVFNDGVC 1201
LC +PC NG FD +++C C + W G+ C++ N C NPCKN G C + C C F G C+ + C ++C NGG+C ++ G +C C GF G C + C P C N+ +C I N C C G TG C E+ ++ C + C NG C+ G C+C F G C ET+ + + KT E L + T+S C D + CK NG C N C ++G C+ +C+ N +H C+ +FND +C
Sbjct: 255 LCELKPCKNGGICRDFDEDYQCICGNQWTGKNCDDVKNPCKINPCKNNGFCESVNYQDYKCICQRGFEGKRCETSIDNCQKISCFNGGSCINMIEGG-KCNCLPGFEGNNCEINVNECENKP------CQNNAKC-IDLNNDYTCDCPEGLTGKNC----EINID-ECTPNPCLNGARCEDRVGGF-TCQCLQGFVGLRC-----ETKSDICKQLTPCKT-EEICLNVNNTRSGYKCICPDGVQNCKKELSKCKNIVCVNGQCVDVNNEEKCICIPGFEGRTCEIEINECFNNPCQHGSQCQDLFNDYLC 544 HSP 6 Score: 74.7146 bits (182), Expect = 5.334e-13 Identity = 78/261 (29.89%), Postives = 103/261 (39.46%), Query Frame = 2
Query: 335 KLCSNRPCVN-GKC----VEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQ--------------FENPCL-NVNCENGGTC-ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKE----------------------LPVEIG----------CKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETR 958
+ C + PC+N G C V P + C+C G+ G CE ++ C NPC + G C +S F C C S++IG C+ F+N L N C++ G C E G F+C C+ G+ G FC V C P C N GEC M FCKC PG+ G C P + CK C NGG+CK + G C C F GK C + E +
Sbjct: 813 RPCDSNPCLNKGSCINRKVNQNTPGYLCNCRRGFTGPRCEIKMDWCRGNPCGDFGVCETDLDS-FKCKCNSEYIGERCEIKKTETCKSYAVEKFKNESLINKICKHHGNCFNDPETGGFKCSCQSGYGGSFCEVNIDDCASQP------CINGGECGDGTGM-YFCKCQPGFQGVNCQVNTNECYSNSCNTGKCIDQINNFSCVCPRGVSGRFCETIVDYCKKMECQNGGICKNVI-GDFECNCPKGFAGKLCETDINECK 1064 HSP 7 Score: 73.9442 bits (180), Expect = 7.732e-13 Identity = 72/262 (27.48%), Postives = 114/262 (43.51%), Query Frame = 2
Query: 2114 RNHQALAFQLISDSLESTDGI---HPIDAGLGDVYT----MASVKNH---------MKYDEKYQTSSLEGLGEYVNENGESLMHIAARMNSGANIIKQINAINPSMLHSLDEWGRTPLASSIAADATESTEQLLILEKQLRKESKQNKVRSGINGINLGTPCEYFVKKTTALIEAVKLDSKEMISLLLDEGSP----VNVLDSQGRSVVHWSAMFNNSGLLERLSHMKIFQKLADLKDNEDKSPLFLAANEGAIDSVKYLLA 2839
RN +A F I++ L S +G+ P ++ + +V N +E S + L V +GE+L+H+AA+ N + A S + L+ GR+ L ++I A A E LE+Q K G +T LI+AVK E+I LLL P +NV D GR+ +HW+A+ + ++ L + + D +DNE+ +PL+LA EG I+ K L+A
Sbjct: 1706 RNIEAWCFNTIANLLVSGNGLGEFSPTESRDKQIIVEKLLQIAVTNQDETNKFADLFNKNELSNNSLITILTSRVPYSGETLLHLAAKYNRKEAARFLLEA--GSDPNKLELNGRSCLMTAIDAGALEVVA--FFLEQQTFVIDLHQKGPYG----------------STCLIQAVKEAHIEIIQLLLQHIQPEECDLNVTDEYGRTALHWAAITGQAAVVHLLMSYGLNR---DAQDNEEATPLYLACKEGVIEVCKILIA 1944 HSP 8 Score: 69.707 bits (169), Expect = 1.420e-11 Identity = 70/235 (29.79%), Postives = 101/235 (42.98%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPG---YTGDRCDK--------KKELPV-----------EIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
C N CVNG+CV+ + E +C C G++G TCE +N+C NPC++G C D N + C C F G C+ N C + C G C G F+C+C + G CA + C +C + D Y C C Y G +C+K + +L + +IG C N C + NGS IC+C ++ G+ C PL R + N
Sbjct: 487 CKNIVCVNGQCVDVNNEE-KCICIPGFEGRTCEIEINECFNNPCQHGSQCQDLFN-DYLCICLPGFKGKKCEININECAHNPCGLNGQCIDEVYG-FRCQCMLPYSGPTCANKLDPCNPNACYNDAICIPGNKYDSY-----HCNCSTALGRYEGSKCEKDVDECNLDRTQLALYGLALLSMSNSQIG----PCLNDNQC-INTNGSFICKCSSQYEGRQCEKPLNNCRNDPCRN 708
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000068721.1 (SMESG000068721.1) HSP 1 Score: 103.605 bits (257), Expect = 6.042e-22 Identity = 77/254 (30.31%), Postives = 121/254 (47.64%), Query Frame = 2
Query: 341 CSNRPCV-NGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKN-SQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPL-KETRKEALINIKIPKTFNEKQLIIKKTKSPSLCDNLCKAS--FENGIC 1084
C RPC NGKC ++C C + + G+ C++ +N C PC+NGG C + N + C C F G C + C+ C NG TC L N + CKC+ GF G++C ++ + C I C N G+C + PN C C G+ G +C++ + CK + C + C L N C C+ + GK C IP K T + LI+ + N+ ++ + ++ + +++C NGIC
Sbjct: 911 CMKRPCKHNGKCSLITHHNYQCDCPYPFHGKNCDKRINACFGQPCRNGGICKNIDNYGNYECVCPVGFRGPKCTINVDDCVGNLCVNGATCNDLNNS-YSCKCQSGFRGKYCDIKFLYCNDI-----NPCQNSGQCQLLPNNDYKCVCSKGWEGKQCERNTD-----DCKYNSCKHESQCVDLHNDYK-CMCRPGYIGKFCEIPAWKPTVLKTLIS---RRDINQSEMTYENLENEVISESVCAYHECLNNGIC 1149 HSP 2 Score: 59.6918 bits (143), Expect = 1.739e-8 Identity = 49/164 (29.88%), Postives = 72/164 (43.90%), Query Frame = 2
Query: 353 PCVN-GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE--NPCL--------NVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGEC---DIYPNMTLFCKCDPGYTGDRC 802
PC N G+C + +++C C GW+G+ CE N +DC N CK+ C+D N + C C +IG C+ P + ++N ++ T E+LEN + CA C N+G C D N +CKC PGY+G C
Sbjct: 1033 PCQNSGQCQLLPNNDYKCVCSKGWEGKQCERNTDDCKYNSCKHESQCVDLHND-YKCMCRPGYIGKFCEIPAWKPTVLKTLISRRDIN-QSEMTYENLENEVIS--------ESVCAYHE-------------CLNNGICINGDQNKNQKSYCKCKPGYSGHLC 1173
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000027402.1 (SMESG000027402.1) HSP 1 Score: 95.9005 bits (237), Expect = 1.252e-19 Identity = 77/217 (35.48%), Postives = 102/217 (47.00%), Query Frame = 2
Query: 341 CSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCI---DKKNSQFTCNCTSQFIGNLCQF-------ENPCLNVNCENGGTCESLE--NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C PC NG C+++ + F C C +G+ G+TCEE + CI++PC N G C+ D+ + F C C + + G LC NPCL NGG+C L NG FQC C G+IG C +I P +++ LC N G C C C PG+ G CD C + CFNGG C + S C C F G NC + E
Sbjct: 631 CKTNPCKNGGICIDSIN-NFECICDNGFFGKTCEERTDYCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLCHLPKHSICDSNPCL-----NGGSCSRLSTLNG-FQCHCNQGWIGTVCQFLHID--FQPCRRKNLCKNEGVCINVGYNDFTCHCKPGFEGKHCDINTN-----ECNPNPCFNGGKC-IDKLNSYRCICAKGFYGSNCQLNYDE 832 HSP 2 Score: 94.3597 bits (233), Expect = 4.038e-19 Identity = 66/202 (32.67%), Postives = 98/202 (48.51%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTC--ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C PC G C+++ EF C C W G+ C+++ + C QN C+NGG C +N C C + G+ C PC N C++ C +S G ++C C+ G+ G++C + C P C N+G C N C C + G C+ + I C++ C NGGVC+ +D G C+CK +TG NC I
Sbjct: 340 CFPNPCKKGTCMKS-KGEFYCQCIERWTGKLCDQDTSICDQNSCQNGGQCGKDENGNRRCICQQGYKGSECHLAAPCENSQCKHALDCQIQSTALGDYKCLCQPGYTGKYCDKEINECVPNP------CKNNGVCTDSIN-DYKCNCSTSFKGKNCE------LNIACQNQPCKNGGVCQEVDTGY-TCKCKTGYTGTNCEI 526 HSP 3 Score: 79.7221 bits (195), Expect = 1.277e-14 Identity = 65/210 (30.95%), Postives = 97/210 (46.19%), Query Frame = 2
Query: 365 GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAV-QNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
G C+ +F C C G++G++CE +++DC NPCKNGG CID N+ F C C + F G C+ + C+ C N G C + + F C+C+ + G C + ++ C P C N G C + F C C+ G+ G C + + + + + C N GVC + C CK F GK+C I E N
Sbjct: 601 GTCLSHEKEKFICRCMPGFEGDSCEIDIDDCKTNPCKNGGICIDSINN-FECICDNGFFGKTCEERTDYCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLCHLPKHSICDSNP------CLNGGSCSRLSTLNGFQCHCNQGWIGTVC-QFLHIDFQPCRRKNLCKNEGVCINVGYNDFTCHCKPGFEGKHCDINTNECNPNPCFN 802 HSP 4 Score: 74.3294 bits (181), Expect = 4.800e-13 Identity = 75/254 (29.53%), Postives = 115/254 (45.28%), Query Frame = 2
Query: 398 RCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLC-QFENPCLNVN-CENGGTCESL--ENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI--PLKETRKEALINIKIPKT-FNEKQLIIKKTKSPSLCD--------NLCKASFENGICDQQCNTFACN 1114
C C GW+G C+E C++ P GTC+D S +TC+C + + G C Q N C N C+NGG CE+L E ++C C GF G C + C P KK + GE +C+C +TG CD+ + C + C NGG C +NG+ C C+ + G C + P + ++ + ++ +I T + + + + + CD N CK NG+C N + CN
Sbjct: 249 ECRCRAGWQGTFCDE----CMKYPGCKHGTCVD---SPWTCSCENNWGGQFCDQSLNYCAENNPCKNGGICENLLSEVQPYKCICPSGFEGRDCEID--PCFPNPCKKGTCMKSKGE--------FYCQCIERWTGKLCDQDTSI-----CDQNSCQNGGQCGKDENGNRRCICQQGYKGSECHLAAPCENSQCKHALDCQIQSTALGDYKCLCQPGYTGKYCDKEINECVPNPCK---NNGVCTDSINDYKCN 477 HSP 5 Score: 62.7734 bits (151), Expect = 1.895e-9 Identity = 46/123 (37.40%), Postives = 62/123 (50.41%), Query Frame = 2
Query: 338 LCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFC-AVQNIACPVIP 700
LC N G C+ +F C C G++G+ C+ N N+C NPC NGG CIDK NS + C C F G+ CQ + C + C G C + F+C+C G G+ C V+N P P
Sbjct: 760 LCKNE----GVCINVGYNDFTCHCKPGFEGKHCDINTNECNPNPCFNGGKCIDKLNS-YRCICAKGFYGSNCQLNYDECASFPCAYGAICVDRIDD-FECRCPEGRDGKLCDHVKNNESPQPP 876 HSP 6 Score: 58.9214 bits (141), Expect = 3.119e-8 Identity = 56/186 (30.11%), Postives = 74/186 (39.78%), Query Frame = 2
Query: 308 GCLLVIVSSKLCSNRPCVNGKCVEAFDP--EFRCSCWHGWKGETCE---ENVNDCIQ-NPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCD--KKKELPVEIGC 838
G L + +C + PC+NG F+C C GW G C+ + C + N CKN G CI+ + FTC+C F G C N C C NGG C N ++C C GF G C + C P +C + + C+C G G CD K E P C
Sbjct: 701 GRLCHLPKHSICDSNPCLNGGSCSRLSTLNGFQCHCNQGWIGTVCQFLHIDFQPCRRKNLCKNEGVCINVGYNDFTCHCKPGFEGKHCDINTNECNPNPCFNGGKCIDKLNS-YRCICAKGFYGSNCQLNYDECASFPCAYGAICVDRID-------DFECRCPEGRDGKLCDHVKNNESPQPPSC 878
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Match: SMESG000027402.1 (SMESG000027402.1) HSP 1 Score: 95.5153 bits (236), Expect = 1.624e-19 Identity = 77/217 (35.48%), Postives = 102/217 (47.00%), Query Frame = 2
Query: 341 CSNRPCVNGK-CVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCI---DKKNSQFTCNCTSQFIGNLCQF-------ENPCLNVNCENGGTCESLE--NGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKE 952
C PC NG C+++ + F C C +G+ G+TCEE + CI++PC N G C+ D+ + F C C + + G LC NPCL NGG+C L NG FQC C G+IG C +I P +++ LC N G C C C PG+ G CD C + CFNGG C + S C C F G NC + E
Sbjct: 624 CKTNPCKNGGICIDSIN-NFECICDNGFFGKTCEERTDYCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLCHLPKHSICDSNPCL-----NGGSCSRLSTLNG-FQCHCNQGWIGTVCQFLHID--FQPCRRKNLCKNEGVCINVGYNDFTCHCKPGFEGKHCDINTN-----ECNPNPCFNGGKC-IDKLNSYRCICAKGFYGSNCQLNYDE 825 HSP 2 Score: 93.9745 bits (232), Expect = 5.373e-19 Identity = 66/202 (32.67%), Postives = 98/202 (48.51%), Query Frame = 2
Query: 341 CSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFENPCLNVNCENGGTC--ESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI 940
C PC G C+++ EF C C W G+ C+++ + C QN C+NGG C +N C C + G+ C PC N C++ C +S G ++C C+ G+ G++C + C P C N+G C N C C + G C+ + I C++ C NGGVC+ +D G C+CK +TG NC I
Sbjct: 333 CFPNPCKKGTCMKS-KGEFYCQCIERWTGKLCDQDTSICDQNSCQNGGQCGKDENGNRRCICQQGYKGSECHLAAPCENSQCKHALDCQIQSTALGDYKCLCQPGYTGKYCDKEINECVPNP------CKNNGVCTDSIN-DYKCNCSTSFKGKNCE------LNIACQNQPCKNGGVCQEVDTGY-TCKCKTGYTGTNCEI 519 HSP 3 Score: 79.337 bits (194), Expect = 1.686e-14 Identity = 65/210 (30.95%), Postives = 97/210 (46.19%), Query Frame = 2
Query: 365 GKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGM---FQCKCRYGFIGEFCAV-QNIACPVIPKKKRELCNNHGECDIYPNMTLF-CKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTIPLKETRKEALIN 976
G C+ +F C C G++G++CE +++DC NPCKNGG CID N+ F C C + F G C+ + C+ C N G C + + F C+C+ + G C + ++ C P C N G C + F C C+ G+ G C + + + + + C N GVC + C CK F GK+C I E N
Sbjct: 594 GTCLSHEKEKFICRCMPGFEGDSCEIDIDDCKTNPCKNGGICIDSINN-FECICDNGFFGKTCEERTDYCIKSPCMNYGVCLRHSDELYNDFICECKNNWGGRLCHLPKHSICDSNP------CLNGGSCSRLSTLNGFQCHCNQGWIGTVC-QFLHIDFQPCRRKNLCKNEGVCINVGYNDFTCHCKPGFEGKHCDINTNECNPNPCFN 795 HSP 4 Score: 73.9442 bits (180), Expect = 6.335e-13 Identity = 75/254 (29.53%), Postives = 115/254 (45.28%), Query Frame = 2
Query: 398 RCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLC-QFENPCLNVN-CENGGTCESL--ENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCDKKKELPVEIGCKSDYCFNGGVCKVLDNGSPICECKGEFTGKNCTI--PLKETRKEALINIKIPKT-FNEKQLIIKKTKSPSLCD--------NLCKASFENGICDQQCNTFACN 1114
C C GW+G C+E C++ P GTC+D S +TC+C + + G C Q N C N C+NGG CE+L E ++C C GF G C + C P KK + GE +C+C +TG CD+ + C + C NGG C +NG+ C C+ + G C + P + ++ + ++ +I T + + + + + CD N CK NG+C N + CN
Sbjct: 242 ECRCRAGWQGTFCDE----CMKYPGCKHGTCVD---SPWTCSCENNWGGQFCDQSLNYCAENNPCKNGGICENLLSEVQPYKCICPSGFEGRDCEID--PCFPNPCKKGTCMKSKGE--------FYCQCIERWTGKLCDQDTSI-----CDQNSCQNGGQCGKDENGNRRCICQQGYKGSECHLAAPCENSQCKHALDCQIQSTALGDYKCLCQPGYTGKYCDKEINECVPNPCK---NNGVCTDSINDYKCN 470 HSP 5 Score: 62.3882 bits (150), Expect = 2.318e-9 Identity = 46/123 (37.40%), Postives = 62/123 (50.41%), Query Frame = 2
Query: 338 LCSNRPCVNGKCVEAFDPEFRCSCWHGWKGETCEENVNDCIQNPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFC-AVQNIACPVIP 700
LC N G C+ +F C C G++G+ C+ N N+C NPC NGG CIDK NS + C C F G+ CQ + C + C G C + F+C+C G G+ C V+N P P
Sbjct: 753 LCKNE----GVCINVGYNDFTCHCKPGFEGKHCDINTNECNPNPCFNGGKCIDKLNS-YRCICAKGFYGSNCQLNYDECASFPCAYGAICVDRIDD-FECRCPEGRDGKLCDHVKNNESPQPP 869 HSP 6 Score: 58.5362 bits (140), Expect = 3.914e-8 Identity = 56/186 (30.11%), Postives = 74/186 (39.78%), Query Frame = 2
Query: 308 GCLLVIVSSKLCSNRPCVNGKCVEAFDP--EFRCSCWHGWKGETCE---ENVNDCIQ-NPCKNGGTCIDKKNSQFTCNCTSQFIGNLCQFE-NPCLNVNCENGGTCESLENGMFQCKCRYGFIGEFCAVQNIACPVIPKKKRELCNNHGECDIYPNMTLFCKCDPGYTGDRCD--KKKELPVEIGC 838
G L + +C + PC+NG F+C C GW G C+ + C + N CKN G CI+ + FTC+C F G C N C C NGG C N ++C C GF G C + C P +C + + C+C G G CD K E P C
Sbjct: 694 GRLCHLPKHSICDSNPCLNGGSCSRLSTLNGFQCHCNQGWIGTVCQFLHIDFQPCRRKNLCKNEGVCINVGYNDFTCHCKPGFEGKHCDINTNECNPNPCFNGGKCIDKLNS-YRCICAKGFYGSNCQLNYDECASFPCAYGAICVDRID-------DFECRCPEGRDGKLCDHVKNNESPQPPSC 871 The following BLAST results are available for this feature:
BLAST of Neurogenic locus Notch protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Neurogenic locus Notch protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Neurogenic locus Notch protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30027457 ID=SMED30027457|Name=Neurogenic locus Notch protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3768bpback to top protein sequence of SMED30027457-orf-1 >SMED30027457-orf-1 ID=SMED30027457-orf-1|Name=SMED30027457-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1096bp MIFAKGFPMNVFILGCLLVIVSSKLCSNRPCVNGKCVEAFDPEFRCSCWHback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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