Myotubularin related protein 12

Overview
NameMyotubularin related protein 12
Smed IDSMED30027446
Length (bp)2098
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Myotubularin related protein 12 (SMED30027446) t-SNE clustered cells

Violin plots show distribution of expression levels for Myotubularin related protein 12 (SMED30027446) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Myotubularin related protein 12 (SMED30027446) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Myotubularin related protein 12 (SMED30027446) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027446

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymaSMED30027446SMESG000019399.1 dd_Smed_v4_1848_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Human
Match: MTMR12 (myotubularin related protein 12 [Source:HGNC Symbol;Acc:HGNC:18191])

HSP 1 Score: 103.99 bits (258), Expect = 2.159e-22
Identity = 125/460 (27.17%), Postives = 188/460 (40.87%), Query Frame = 1 
Query:  454 FIITCYDFRVYSY----------NRI--SIYNKNDAIKFYQEIFRLVFETE-------DDRMKCDMWMKIGD---EVLR---DVYYK--TVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLK-------HISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM-------------NSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
             II C D RV+ +           RI   I +   A K  + +F   + T        D +    M+  + D   E+ R   ++ YK  +VN   +V  + +  Y VV P  L   N++     G  +  +S HN S L+ +     ++    L+        I KTI  P  ++V        +E+ S  +  + +E+  ++ K   L    N  EF   D KW S      WL+++ RCL+    I + M     +V L+E+       L  SLVQ++  P  RTR GF S+I+K W+M         N    +D  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F                 D   K +      DWS+ F  +    L N  Y+E+        PK+D        FK + R +     +S S   R FF
Sbjct:  139 LIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKV-CERLPAYFVV-PTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIV-------KTEDLSSNFL-SLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEK--------PKLDKGQRKGMRFK-HQRQLSLPLTQSKSSPKRGFF 579
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Human
Match: MTMR12 (myotubularin related protein 12 [Source:HGNC Symbol;Acc:HGNC:18191])

HSP 1 Score: 100.908 bits (250), Expect = 1.806e-21
Identity = 124/475 (26.11%), Postives = 191/475 (40.21%), Query Frame = 1 
Query:  454 FIITCYDFRVYSY----------NRI--SIYNKNDAIKFYQEIFRLVFETE-------DDRMKCDMWMKIGD---EVLR---DVYYK--TVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLK-------HISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM----NSLDYDFKGIDWSL-------------------YFVDQVL------------ECLDNYYYLEESFDS------CLFVPKVDVMDFGSFWFKMYARWIPYVQIESGS 1626
             II C D RV+ +           RI   I +   A K  + +F   + T        D +    M+  + D   E+ R   ++ YK  +VN   +V  + +  Y VV P  L   N++     G  +  +S HN S L+ +     ++    L+        I KTI  P  ++V        +E+ S  +  + +E+  ++ K   L    N  EF   D KW S      WL+++ RCL+    I + M     +V L+E+       L  SLVQ++  P  RTR GF S+I+K W+M         N    +D  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F     +  D +      SL                   + +  +L            E  DN+    +S+ S       L +P ++  +    W + Y RWIP  QI  G 
Sbjct:  139 LIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKV-CERLPAYFVV-PTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIV-------KTEDLSSNFL-SLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMHQRQLSLPLTQSKSSPKRGFFREETDHLIKNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEI-KVWAQRYLRWIPEAQILGGG 602
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Human
Match: MTMR10 (myotubularin related protein 10 [Source:HGNC Symbol;Acc:HGNC:25999])

HSP 1 Score: 82.0333 bits (201), Expect = 2.285e-16
Identity = 55/161 (34.16%), Postives = 80/161 (49.69%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P  +E+  +F KL  LC       F++ ++KWLS   +  WL  V   L+ +  ++  +     SV L E+          SLVQ++  P+ RT  GF S+I+K W+M+        N    S+  +  LFLLFLD  +QLL   P  FEF+E  L  LYD
Sbjct:  102 PNIQEVQAAFVKLKQLCV---NEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEK-ESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYD 258
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Human
Match: MTMR10 (myotubularin related protein 10 [Source:HGNC Symbol;Acc:HGNC:25999])

HSP 1 Score: 82.8037 bits (203), Expect = 5.512e-16
Identity = 55/161 (34.16%), Postives = 80/161 (49.69%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P  +E+  +F KL  LC       F++ ++KWLS   +  WL  V   L+ +  ++  +     SV L E+          SLVQ++  P+ RT  GF S+I+K W+M+        N    S+  +  LFLLFLD  +QLL   P  FEF+E  L  LYD
Sbjct:  255 PNIQEVQAAFVKLKQLCV---NEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEK-ESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYD 411
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Human
Match: MTMR10 (myotubularin related protein 10 [Source:HGNC Symbol;Acc:HGNC:25999])

HSP 1 Score: 82.4185 bits (202), Expect = 1.486e-15
Identity = 69/229 (30.13%), Postives = 101/229 (44.10%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD----------LFILAPSGFMNSLDY---------DFKGI------DWSLYFVDQVLECLDNYYYLEES 1518
            P  +E+  +F KL  LC       F++ ++KWLS   +  WL  V   L+ +  ++  +     SV L E+          SLVQ++  P+ RT  GF S+I+K W+M+        N    S+  +  LFLLFLD  +QLL   P  FEF+E  L  LYD          LF         S ++         D KG+      DWSL F  +      N +Y+ +S
Sbjct:  337 PNIQEVQAAFVKLKQLCV---NEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEK-ESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIGKS 561
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Celegans
Match: Y48G1C.10 (pep chromosome:WBcel235:I:81203:91020:1 gene:WBGene00021683.1 transcript:Y48G1C.10a.3 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y48G1C.10)

HSP 1 Score: 80.1073 bits (196), Expect = 2.512e-15
Identity = 74/262 (28.24%), Postives = 107/262 (40.84%), Query Frame = 1 
Query:  952 ESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWI-MSNAF------YNSDGPKY-------------SLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFI--LAPSGFMNSLDYDF----KGIDWSL--YFVDQVLECLDNYYY----------------LEESFDSCLFV-PKVDVMDFGSFWFKMYARWIP 1602
            ++F+ L  LC   +  ++      W +K +  GWL+LV  CLQ+T   ++ + +   SV L E        +  SL Q+ C PF RT  G   +IEK WI + + F         D P                 +LLFLDCV QL R   F F F+  +LI L+DL +  + PS   N+L+        G  + L  YF     +   N ++                    F  C F+ P     D    W + Y RWIP
Sbjct:  322 KAFDNLLSLCAIDSYEQYVTLQNGWNTKLSRTGWLHLVKLCLQTTYQTIQWIVDRDRSVILQEDEGSDMSIIVASLTQMCCDPFYRTTTGLQQLIEKMWIALGHPFGERLLGRTDDDPSRRGKPQNKMRTDVMPTWLLFLDCVSQLHRIYTFEFTFSPHVLIALWDLSLTGMVPSMACNNLEEQLLAKVGGGPFPLDRYFEKSYSKLFGNIWHDAVLFMESIKKNQPVCAHSKFLQCEFIRPPTSFCDI-QLWSECYLRWIP 582
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Celegans
Match: Y48G1C.10 (pep chromosome:WBcel235:I:81193:90957:1 gene:WBGene00021683.1 transcript:Y48G1C.10a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y48G1C.10)

HSP 1 Score: 80.1073 bits (196), Expect = 2.512e-15
Identity = 74/262 (28.24%), Postives = 107/262 (40.84%), Query Frame = 1 
Query:  952 ESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWI-MSNAF------YNSDGPKY-------------SLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFI--LAPSGFMNSLDYDF----KGIDWSL--YFVDQVLECLDNYYY----------------LEESFDSCLFV-PKVDVMDFGSFWFKMYARWIP 1602
            ++F+ L  LC   +  ++      W +K +  GWL+LV  CLQ+T   ++ + +   SV L E        +  SL Q+ C PF RT  G   +IEK WI + + F         D P                 +LLFLDCV QL R   F F F+  +LI L+DL +  + PS   N+L+        G  + L  YF     +   N ++                    F  C F+ P     D    W + Y RWIP
Sbjct:  322 KAFDNLLSLCAIDSYEQYVTLQNGWNTKLSRTGWLHLVKLCLQTTYQTIQWIVDRDRSVILQEDEGSDMSIIVASLTQMCCDPFYRTTTGLQQLIEKMWIALGHPFGERLLGRTDDDPSRRGKPQNKMRTDVMPTWLLFLDCVSQLHRIYTFEFTFSPHVLIALWDLSLTGMVPSMACNNLEEQLLAKVGGGPFPLDRYFEKSYSKLFGNIWHDAVLFMESIKKNQPVCAHSKFLQCEFIRPPTSFCDI-QLWSECYLRWIP 582
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Celegans
Match: Y48G1C.10 (pep chromosome:WBcel235:I:81193:91020:1 gene:WBGene00021683.1 transcript:Y48G1C.10a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y48G1C.10)

HSP 1 Score: 80.1073 bits (196), Expect = 2.512e-15
Identity = 74/262 (28.24%), Postives = 107/262 (40.84%), Query Frame = 1 
Query:  952 ESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWI-MSNAF------YNSDGPKY-------------SLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFI--LAPSGFMNSLDYDF----KGIDWSL--YFVDQVLECLDNYYY----------------LEESFDSCLFV-PKVDVMDFGSFWFKMYARWIP 1602
            ++F+ L  LC   +  ++      W +K +  GWL+LV  CLQ+T   ++ + +   SV L E        +  SL Q+ C PF RT  G   +IEK WI + + F         D P                 +LLFLDCV QL R   F F F+  +LI L+DL +  + PS   N+L+        G  + L  YF     +   N ++                    F  C F+ P     D    W + Y RWIP
Sbjct:  322 KAFDNLLSLCAIDSYEQYVTLQNGWNTKLSRTGWLHLVKLCLQTTYQTIQWIVDRDRSVILQEDEGSDMSIIVASLTQMCCDPFYRTTTGLQQLIEKMWIALGHPFGERLLGRTDDDPSRRGKPQNKMRTDVMPTWLLFLDCVSQLHRIYTFEFTFSPHVLIALWDLSLTGMVPSMACNNLEEQLLAKVGGGPFPLDRYFEKSYSKLFGNIWHDAVLFMESIKKNQPVCAHSKFLQCEFIRPPTSFCDI-QLWSECYLRWIP 582
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Celegans
Match: mtm-9 (Myotubularin-related protein 9 [Source:UniProtKB/Swiss-Prot;Acc:Q965W9])

HSP 1 Score: 68.9366 bits (167), Expect = 6.464e-12
Identity = 47/169 (27.81%), Postives = 80/169 (47.34%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSM-SESCSSVFLMEQGYPTWG--WLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSN------------AFYNSDGP-KYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P  +E+ ++  ++  +C+ R     K    +W+S+    GWL+ V   L++   + + + +E    V ++  G        +  SL QI+     RT  GF S+IE+ WI               A     GP +  +FL+FLD V+Q++   P  FEF+E  LIFL++
Sbjct:  231 PRQREIHDALTRMVDVCSER-----KVTSDRWVSRVGQAGWLSSVAASLEAAANVAQCIYNERLEEVPVVIHGGDGLDSTLIASSLAQILLDADARTIRGFESVIEREWICGGHPFSLRNNHCAYAEGTVTGPFESPVFLVFLDAVHQMIAQYPMSFEFDENFLIFLFE 394
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Celegans
Match: mtm-9 (Myotubularin-related protein 9 [Source:UniProtKB/Swiss-Prot;Acc:Q965W9])

HSP 1 Score: 68.5514 bits (166), Expect = 8.125e-12
Identity = 47/169 (27.81%), Postives = 80/169 (47.34%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSM-SESCSSVFLMEQGYPTW--GWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSN------------AFYNSDGP-KYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P  +E+ ++  ++  +C+ R     K    +W+S+    GWL+ V   L++   + + + +E    V ++  G        +  SL QI+     RT  GF S+IE+ WI               A     GP +  +FL+FLD V+Q++   P  FEF+E  LIFL++
Sbjct:  279 PRQREIHDALTRMVDVCSER-----KVTSDRWVSRVGQAGWLSSVAASLEAAANVAQCIYNERLEEVPVVIHGGDGLDSTLIASSLAQILLDADARTIRGFESVIEREWICGGHPFSLRNNHCAYAEGTVTGPFESPVFLVFLDAVHQMIAQYPMSFEFDENFLIFLFE 442
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Fly
Match: CG5026 (gene:FBgn0035945 transcript:FBtr0301141)

HSP 1 Score: 78.5666 bits (192), Expect = 9.704e-15
Identity = 65/252 (25.79%), Postives = 106/252 (42.06%), Query Frame = 1 
Query:  910 NKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFYNS-------------DGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFL--------YDLFILAPSGFMNSLDYDFKGID-WSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWI 1599
            N+S     +   +++SF +L   C      +      KWLS+  + GWL+LV   L ++ ++ + + +  S V +          +  SLVQII  P  RT  G  ++IE+ WI +   + S             +    + F+LFLDC+YQL    P  FEF+ ++LI L        Y  F+       N L+   +    WS      VL+   N  Y     ++ +  P V  +     W  +Y RW+
Sbjct:  327 NRSIGNVSSPASILDSFARLIEACN-----DLGCSTDKWLSRLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAGHPFASRHRYSCYTPNQTRNKTSGATFVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDSERERNELNVHTRTTSLWSYLNRPDVLQTFLNPLY---EPNANVIWPSVAPISL-ELWSDLYLRWV 569
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Fly
Match: CG5026 (gene:FBgn0035945 transcript:FBtr0076515)

HSP 1 Score: 78.5666 bits (192), Expect = 9.704e-15
Identity = 65/252 (25.79%), Postives = 106/252 (42.06%), Query Frame = 1 
Query:  910 NKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFYNS-------------DGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFL--------YDLFILAPSGFMNSLDYDFKGID-WSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWI 1599
            N+S     +   +++SF +L   C      +      KWLS+  + GWL+LV   L ++ ++ + + +  S V +          +  SLVQII  P  RT  G  ++IE+ WI +   + S             +    + F+LFLDC+YQL    P  FEF+ ++LI L        Y  F+       N L+   +    WS      VL+   N  Y     ++ +  P V  +     W  +Y RW+
Sbjct:  327 NRSIGNVSSPASILDSFARLIEACN-----DLGCSTDKWLSRLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAGHPFASRHRYSCYTPNQTRNKTSGATFVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDSERERNELNVHTRTTSLWSYLNRPDVLQTFLNPLY---EPNANVIWPSVAPISL-ELWSDLYLRWV 569
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Fly
Match: CG5026 (gene:FBgn0035945 transcript:FBtr0076516)

HSP 1 Score: 78.5666 bits (192), Expect = 9.704e-15
Identity = 65/252 (25.79%), Postives = 106/252 (42.06%), Query Frame = 1 
Query:  910 NKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFYNS-------------DGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFL--------YDLFILAPSGFMNSLDYDFKGID-WSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWI 1599
            N+S     +   +++SF +L   C      +      KWLS+  + GWL+LV   L ++ ++ + + +  S V +          +  SLVQII  P  RT  G  ++IE+ WI +   + S             +    + F+LFLDC+YQL    P  FEF+ ++LI L        Y  F+       N L+   +    WS      VL+   N  Y     ++ +  P V  +     W  +Y RW+
Sbjct:  327 NRSIGNVSSPASILDSFARLIEACN-----DLGCSTDKWLSRLENSGWLSLVLNSLNASCVVAQCLDQEGSPVLVHGAKGLDSTLIVTSLVQIILNPDCRTVRGLQALIEREWIQAGHPFASRHRYSCYTPNQTRNKTSGATFVLFLDCIYQLYTQFPCSFEFSTQLLILLFEHSHFSQYGTFLCDSERERNELNVHTRTTSLWSYLNRPDVLQTFLNPLY---EPNANVIWPSVAPISL-ELWSDLYLRWV 569
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Fly
Match: CG14411 (gene:FBgn0030582 transcript:FBtr0300433)

HSP 1 Score: 77.411 bits (189), Expect = 2.904e-14
Identity = 51/171 (29.82%), Postives = 82/171 (47.95%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIM---------------SNAFYNS---DGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P+ ++++ +++KL  LCTP    +F  +D K+L       WL  V+ CL+       ++    + V L E        +  SL Q++  P  RT +GF S+++K W+                  A  N+   D  +  +FLLFLDCV+QLL+  P  FEF +  L  L+D
Sbjct:  401 PSIQDVLRAYQKLRRLCTPETPEKFMLQDDKYLGLLEKTNWLFYVSLCLRYASEASATLRSGVTCV-LQESNGRDLCCVISSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSEQSPVFLLFLDCVWQLLQQFPDEFEFTQTYLTTLWD 570
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Fly
Match: CG14411 (gene:FBgn0030582 transcript:FBtr0300432)

HSP 1 Score: 77.411 bits (189), Expect = 2.904e-14
Identity = 51/171 (29.82%), Postives = 82/171 (47.95%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIM---------------SNAFYNS---DGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P+ ++++ +++KL  LCTP    +F  +D K+L       WL  V+ CL+       ++    + V L E        +  SL Q++  P  RT +GF S+++K W+                  A  N+   D  +  +FLLFLDCV+QLL+  P  FEF +  L  L+D
Sbjct:  401 PSIQDVLRAYQKLRRLCTPETPEKFMLQDDKYLGLLEKTNWLFYVSLCLRYASEASATLRSGVTCV-LQESNGRDLCCVISSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSEQSPVFLLFLDCVWQLLQQFPDEFEFTQTYLTTLWD 570
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Zebrafish
Match: mtmr12 (myotubularin related protein 12 [Source:NCBI gene;Acc:569130])

HSP 1 Score: 80.4925 bits (197), Expect = 3.869e-15
Identity = 48/162 (29.63%), Postives = 83/162 (51.23%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYS-LFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            PT +++ +S+ K        N  +F   D KW S     GWL+++ +CLQ    +++ + +  ++V + E+       +  SL QI+  P+ RT  GF S+++K W+          N  +  D   +S +FLLFL+CV+QL++     F+F+E  L  L D
Sbjct:  309 PTLQDIQQSYNKFKQYFLIDNTTDFWLSDVKWFSSLESSGWLDIIRQCLQKAVEVVECLEKDNTNVLITEEEGTDLCCVISSLAQIMLDPYYRTLMGFQSLVQKEWVAGCHAFLDRCNHLHQKDKECHSPVFLLFLECVWQLVQQHSPAFQFSETYLTVLSD 470
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Zebrafish
Match: mtmr12 (myotubularin related protein 12 [Source:NCBI gene;Acc:569130])

HSP 1 Score: 80.1073 bits (196), Expect = 4.111e-15
Identity = 48/162 (29.63%), Postives = 83/162 (51.23%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYS-LFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            PT +++ +S+ K        N  +F   D KW S     GWL+++ +CLQ    +++ + +  ++V + E+       +  SL QI+  P+ RT  GF S+++K W+          N  +  D   +S +FLLFL+CV+QL++     F+F+E  L  L D
Sbjct:  326 PTLQDIQQSYNKFKQYFLIDNTTDFWLSDVKWFSSLESSGWLDIIRQCLQKAVEVVECLEKDNTNVLITEEEGTDLCCVISSLAQIMLDPYYRTLMGFQSLVQKEWVAGCHAFLDRCNHLHQKDKECHSPVFLLFLECVWQLVQQHSPAFQFSETYLTVLSD 487
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Zebrafish
Match: mtmr10 (myotubularin related protein 10 [Source:NCBI gene;Acc:555239])

HSP 1 Score: 80.1073 bits (196), Expect = 4.306e-15
Identity = 51/161 (31.68%), Postives = 80/161 (49.69%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P  +++  +  KL  +C   +   F++ ++KWLS      W+  V   L+    ++  +     SV L+E+       +  SLVQ++C P  R+ +GF ++I+K W+M+        N    SD  +  LFLLFLDCV+QL    P  FEF E  L  L D
Sbjct:  322 PNIQDIQAALLKLRQICVIES---FEESEEKWLSSLESSRWMEYVRTFLRHAVEVVYMLESRHVSVILLEKEDRDLSCVISSLVQLMCDPHCRSLHGFQALIQKEWVMAGHRFLDRCNHLKKSDKEESPLFLLFLDCVWQLWNQYPAAFEFTEVYLTVLGD 479
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Zebrafish
Match: mtmr11 (myotubularin related protein 11 [Source:ZFIN;Acc:ZDB-GENE-130530-726])

HSP 1 Score: 76.6406 bits (187), Expect = 5.374e-14
Identity = 48/161 (29.81%), Postives = 73/161 (45.34%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P+  ++  +  +L  LC     +     D KWLS      WL+    CL+    +   +     +V L E        +  SLVQ++C P  RT  GF  +++K WI +        N    SD  +  +FLLFLDCV+QL    P  F+  E+ L+ L+D
Sbjct:  318 PSPADIQLAHTRLRTLCLGDISSSVSVPDDKWLSTLESTRWLDYTRCCLRKAAEVCCLLRAGHMTVVLQEPEDRDMNCVVCSLVQVMCDPHCRTVAGFQGLVQKEWITAGHKFLSRINYHRESDKEEAPVFLLFLDCVWQLWAQYPARFQLTEDYLLALHD 478
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Zebrafish
Match: mtmr11 (myotubularin related protein 11 [Source:ZFIN;Acc:ZDB-GENE-130530-726])

HSP 1 Score: 76.6406 bits (187), Expect = 5.374e-14
Identity = 48/161 (29.81%), Postives = 73/161 (45.34%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P+  ++  +  +L  LC     +     D KWLS      WL+    CL+    +   +     +V L E        +  SLVQ++C P  RT  GF  +++K WI +        N    SD  +  +FLLFLDCV+QL    P  F+  E+ L+ L+D
Sbjct:  318 PSPADIQLAHTRLRTLCLGDISSSVSVPDDKWLSTLESTRWLDYTRCCLRKAAEVCCLLRAGHMTVVLQEPEDRDMNCVVCSLVQVMCDPHCRTVAGFQGLVQKEWITAGHKFLSRINYHRESDKEEAPVFLLFLDCVWQLWAQYPARFQLTEDYLLALHD 478
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Xenopus
Match: hoxa13 (homeobox A13 [Source:Xenbase;Acc:XB-GENE-479980])

HSP 1 Score: 101.293 bits (251), Expect = 1.073e-21
Identity = 90/309 (29.13%), Postives = 139/309 (44.98%), Query Frame = 1 
Query:  511 NKNDA--IKFYQEIFRLV--FETEDDRMKCDMWMKIGDEVLRDVYYKTVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQ--VVYYSDHNDSCLIVIDKSSGKKCSNSLKHISKTILGPKIKVVLF--HLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            NK D   + F  ++F     +E E DR++   W               VN        S+ KY+VV P  L  N+LK  F    Q  V  +S H+     ++  +  +  +   K   ++I     + +LF  H  C   +   E   P+  ++  ++ KL  LC   N       D+KWLS      WL+ V  CL+ +  I   + E   SV L E        L  SLVQ++  PFVRT +GF S+++K W+ +        N F  +D  +  +F+LFLDC++QL++  P  FEF E  L+ L+D
Sbjct:  148 NKQDGSPVDFPMQLFESYSDWENEIDRLRASAWR-----------VSPVNERCDTS-TSLSKYIVV-PCKLLDNDLKKTFAHFNQRRVPRWSWHHPGGSDLLRSAGFETNTEPDKENMRSI-----RSLLFANHSQCVIVDTSDEL--PSVSDIQLAYGKLRTLCI--NDPSVTVSDEKWLSNMEGTRWLDHVRLCLKKSSEISIFLGEGKRSVVLQESEDRDLNCLLASLVQVMSDPFVRTISGFQSLVQKEWVSAGHPFLQRINPFKETDKDESPVFVLFLDCIWQLIQQFPSAFEFTESYLLALHD 434
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Xenopus
Match: nrip3 (nuclear receptor interacting protein 3 [Source:Xenbase;Acc:XB-GENE-997031])

HSP 1 Score: 95.9005 bits (237), Expect = 6.996e-20
Identity = 102/411 (24.82%), Postives = 172/411 (41.85%), Query Frame = 1 
Query:  454 FIITCYDFRVYSY----------NRI--SIYNKNDAIKFYQEIF-------RLVFETEDDRMKCDMWMKIGDEVLRDVYYK--TVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIV-------IDKSSGKKCSNSLKHISKTILGPKIKVVLFHLNCENSENKSEF---YCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFY-------NSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD---------LFILAP---------SGFMNSLDYDFKGIDWSLYFVDQVLECLDNYYYLEES 1518
             I+ C DFRV+ +           RI   I +   + K  + +F        L+FET  D      WM   +    +++YK  T N   +V  + + +Y VV P+ L  + L D    G  +  +S  N S L+        +D  + +     L  + KT+  P  + V       +  + SE    YC         F++L+++    N  +F   D KW S      W+ ++ +CL+    +++ +     +V L E     +  +  SLVQI+  P+ RT+ GF S+++K W+M    +         +  +  +FLLFLDCV+QL++  P  FEF E  L  L D          F  +P          G        +   DWS+ F  + +  L+N  Y+E++
Sbjct:  109 LIVYCKDFRVFHFCLSYTKQEEVKRIVSGIIHHTQSPKLLKRLFLFSYAAATLMFETVKD------WMAELERTKGNLHYKVLTANEGYKVS-ERLPQYFVV-PMSLPEDTLTDFQGRGVPIWCWSCPNGSALLKMASLPKDVDDVALQHQRTFLDRVEKTLHRPPYEEVRIEDLTASLPSLSEVQVAYC--------RFKQLFLI---ENSTDFWDTDLKWFSSLDTSNWMEIIRQCLRKAVEVIEYLETHKINVVLKEDTAYDFCCIISSLVQIMMDPYCRTKIGFQSLVQKEWVMGGHCFLDRCNHLRKNENEAPVFLLFLDCVWQLVQQYPLAFEFTETYLTVLSDSINIPIFSTFFFNSPWQKDTHKGRQGKQGESLRFYTVWDWSVQFEPKAISFLNNPLYVEKA 500
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Xenopus
Match: nrip3 (nuclear receptor interacting protein 3 [Source:Xenbase;Acc:XB-GENE-997031])

HSP 1 Score: 92.4337 bits (228), Expect = 1.040e-18
Identity = 91/361 (25.21%), Postives = 156/361 (43.21%), Query Frame = 1 
Query:  553 LVFETEDDRMKCDMWMKIGDEVLRDVYYK--TVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIV-------IDKSSGKKCSNSLKHISKTILGPKIKVVLFHLNCENSENKSEF---YCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFY-------NSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD---LFILAPSGFMNSLDYDFKGI-----------------DWSLYFVDQVLECLDNYYYLEES 1518
            L+FET  D      WM   +    +++YK  T N   +V  + + +Y VV P+ L  + L D    G  +  +S  N S L+        +D  + +     L  + KT+  P  + V       +  + SE    YC         F++L+++    N  +F   D KW S      W+ ++ +CL+    +++ +     +V L E     +  +  SLVQI+  P+ RT+ GF S+++K W+M    +         +  +  +FLLFLDCV+QL++  P  FEF E  L  L D   + I +   F +    D   +                 DWS+ F  + +  L+N  Y+E++
Sbjct:  201 LMFETVKD------WMAELERTKGNLHYKVLTANEGYKVS-ERLPQYFVV-PMSLPEDTLTDFQGRGVPIWCWSCPNGSALLKMASLPKDVDDVALQHQRTFLDRVEKTLHRPPYEEVRIEDLTASLPSLSEVQVAYC--------RFKQLFLI---ENSTDFWDTDLKWFSSLDTSNWMEIIRQCLRKAVEVIEYLETHKINVVLKEDTAYDFCCIISSLVQIMMDPYCRTKIGFQSLVQKEWVMGGHCFLDRCNHLRKNENEAPVFLLFLDCVWQLVQQYPLAFEFTETYLTVLSDSINIPIFSTFFFNSPWQKDTHSVEGRQGKQGESLRFYTVWDWSVQFEPKAISFLNNPLYVEKA 542
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Xenopus
Match: nrip3 (nuclear receptor interacting protein 3 [Source:Xenbase;Acc:XB-GENE-997031])

HSP 1 Score: 92.0485 bits (227), Expect = 1.222e-18
Identity = 92/360 (25.56%), Postives = 159/360 (44.17%), Query Frame = 1 
Query:  553 LVFETEDDRMKCDMWMKIGDEVLRDVYYK--TVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIV-------IDKSSGKKCSNSLKHISKTILGPKIKVVLFHLNCENSENKSEF---YCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFY-------NSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD---------LFILAP----SGFMNSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEES 1518
            L+FET  D      WM   +    +++YK  T N   +V  + + +Y VV P+ L  + L D    G  +  +S  N S L+        +D  + +     L  + KT+  P  + V       +  + SE    YC         F++L+++    N  +F   D KW S      W+ ++ +CL+    +++ +     +V L E     +  +  SLVQI+  P+ RT+ GF S+++K W+M    +         +  +  +FLLFLDCV+QL++  P  FEF E  L  L D          F  +P    +   ++L +  K +      DWS+ F  + +  L+N  Y+E++
Sbjct:  187 LMFETVKD------WMAELERTKGNLHYKVLTANEGYKVS-ERLPQYFVV-PMSLPEDTLTDFQGRGVPIWCWSCPNGSALLKMASLPKDVDDVALQHQRTFLDRVEKTLHRPPYEEVRIEDLTASLPSLSEVQVAYC--------RFKQLFLI---ENSTDFWDTDLKWFSSLDTSNWMEIIRQCLRKAVEVIEYLETHKINVVLKEDTAYDFCCIISSLVQIMMDPYCRTKIGFQSLVQKEWVMGGHCFLDRCNHLRKNENEAPVFLLFLDCVWQLVQQYPLAFEFTETYLTVLSDSINIPIFSTFFFNSPWQKDTHRHSNLYHITKSLRFYTVWDWSVQFEPKAISFLNNPLYVEKA 527
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Xenopus
Match: nrip3 (nuclear receptor interacting protein 3 [Source:Xenbase;Acc:XB-GENE-997031])

HSP 1 Score: 92.0485 bits (227), Expect = 1.297e-18
Identity = 93/359 (25.91%), Postives = 157/359 (43.73%), Query Frame = 1 
Query:  553 LVFETEDDRMKCDMWMKIGDEVLRDVYYK--TVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIV-------IDKSSGKKCSNSLKHISKTILGPKIKVVLFHLNCENSENKSEF---YCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFY-------NSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD---LFILAPSGFMNSLDYD-FKGI--------------DWSLYFVDQVLECLDNYYYLEES 1518
            L+FET  D      WM   +    +++YK  T N   +V  + + +Y VV P+ L  + L D    G  +  +S  N S L+        +D  + +     L  + KT+  P  + V       +  + SE    YC         F++L+++    N  +F   D KW S      W+ ++ +CL+    +++ +     +V L E     +  +  SLVQI+  P+ RT+ GF S+++K W+M    +         +  +  +FLLFLDCV+QL++  P  FEF E  L  L D   + I +   F +    D  KG               DWS+ F  + +  L+N  Y+E++
Sbjct:  187 LMFETVKD------WMAELERTKGNLHYKVLTANEGYKVS-ERLPQYFVV-PMSLPEDTLTDFQGRGVPIWCWSCPNGSALLKMASLPKDVDDVALQHQRTFLDRVEKTLHRPPYEEVRIEDLTASLPSLSEVQVAYC--------RFKQLFLI---ENSTDFWDTDLKWFSSLDTSNWMEIIRQCLRKAVEVIEYLETHKINVVLKEDTAYDFCCIISSLVQIMMDPYCRTKIGFQSLVQKEWVMGGHCFLDRCNHLRKNENEAPVFLLFLDCVWQLVQQYPLAFEFTETYLTVLSDSINIPIFSTFFFNSPWQKDTHKGRQGKQGESLRFYTVWDWSVQFEPKAISFLNNPLYVEKA 526
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Mouse
Match: Mtmr12 (myotubularin related protein 12 [Source:MGI Symbol;Acc:MGI:2443034])

HSP 1 Score: 105.145 bits (261), Expect = 7.769e-23
Identity = 123/459 (26.80%), Postives = 186/459 (40.52%), Query Frame = 1 
Query:  454 FIITCYDFRVYSY----------NRI--SIYNKNDAIKFYQEIF-----RLVFETEDDRMKCDM-------WMKIGDEVLRDVYYKTV--NNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLK-------HISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM-------------NSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
             +I C D RV  +           RI   I +   + K  + +F       V  T  D   C +       W    +     V Y+TV  N   RV    +  Y VV P  L  ++++     G  +  +S HN S L+ +     ++   +L+        I KTI  P  ++V        +E+ S  +  + +E+  ++ K   L    N +EF   D KW S      WL+++ RCL+    I + +     +V L+E+       L  SLVQ++     RTR GF S+I+K W+M         N  + SD  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F               +LD   K +      DWS+ F  +    L N  Y+E+        PK+D        FK + R +     +S S   R FF
Sbjct:  140 LVIHCKDLRVLHFCLRYTKEEEVKRIVSGIIHHTQSPKLLKRLFLFSYAAAVHGTATDSRNCTVMFDTPKDWCWELERTKGSVKYRTVSVNEGYRVS-DRLPAYFVV-PTPLPEDDVRRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGALQVQKSFLDGIYKTIHRPPYEMV-------KTEDLSSNFL-SLQEIQSAYCKFKQLFLIDNSSEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECLEAQNVNVLLLEENASDLCCLLSSLVQVMMDAHCRTRTGFQSLIQKEWVMGGHSFLDRCNHLHQSDKEEVPIFLLFLDCVWQLVHQYPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGRENLDAQSKPLTLLTVWDWSVQFEPKAQTLLRNPLYVEK--------PKLDRGQQKGSRFK-HQRQLSLPLTQSKSSPKRGFF 579
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Mouse
Match: Mtmr12 (myotubularin related protein 12 [Source:MGI Symbol;Acc:MGI:2443034])

HSP 1 Score: 101.293 bits (251), Expect = 5.495e-22
Identity = 97/353 (27.48%), Postives = 148/353 (41.93%), Query Frame = 1 
Query:  454 FIITCYDFRVYSY----------NRI--SIYNKNDAIKFYQEIF-----RLVFETEDDRMKCDM-------WMKIGDEVLRDVYYKTV--NNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLK-------HISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
             +I C D RV  +           RI   I +   + K  + +F       V  T  D   C +       W    +     V Y+TV  N   RV    +  Y VV P  L  ++++     G  +  +S HN S L+ +     ++   +L+        I KTI  P  ++V      +  +  S F   + +E+  ++ K   L    N +EF   D KW S      WL+++ RCL+    I + +     +V L+E+       L  SLVQ++     RTR GF S+I+K W+M         N  + SD  +  +FLLFLDCV+QL+   P  FEF E  L  L D
Sbjct:  140 LVIHCKDLRVLHFCLRYTKEEEVKRIVSGIIHHTQSPKLLKRLFLFSYAAAVHGTATDSRNCTVMFDTPKDWCWELERTKGSVKYRTVSVNEGYRVS-DRLPAYFVV-PTPLPEDDVRRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGALQVQKSFLDGIYKTIHRPPYEMV------KTEDLSSNFL--SLQEIQSAYCKFKQLFLIDNSSEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECLEAQNVNVLLLEENASDLCCLLSSLVQVMMDAHCRTRTGFQSLIQKEWVMGGHSFLDRCNHLHQSDKEEVPIFLLFLDCVWQLVHQYPPAFEFTETYLTVLSD 482
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Mouse
Match: Mtmr12 (myotubularin related protein 12 [Source:MGI Symbol;Acc:MGI:2443034])

HSP 1 Score: 90.5077 bits (223), Expect = 9.029e-19
Identity = 71/227 (31.28%), Postives = 101/227 (44.49%), Query Frame = 1 
Query: 1051 WLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGF-------------MNSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
            WL+++ RCL+    I + +     +V L+E+       L  SLVQ++     RTR GF S+I+K W+M         N  + SD  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F               +LD   K +      DWS+ F  +    L N  Y+E+        PK+D        FK + R +     +S S   R FF
Sbjct:   52 WLDIIRRCLKKAIEITECLEAQNVNVLLLEENASDLCCLLSSLVQVMMDAHCRTRTGFQSLIQKEWVMGGHSFLDRCNHLHQSDKEEVPIFLLFLDCVWQLVHQYPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGRENLDAQSKPLTLLTVWDWSVQFEPKAQTLLRNPLYVEK--------PKLDRGQQKGSRFK-HQRQLSLPLTQSKSSPKRGFF 269
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Mouse
Match: Mtmr10 (myotubularin related protein 10 [Source:MGI Symbol;Acc:MGI:2142292])

HSP 1 Score: 78.9518 bits (193), Expect = 1.305e-14
Identity = 54/161 (33.54%), Postives = 79/161 (49.07%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P  +E+  +F KL  LC       F++ ++KWLS      WL  V   L+ +  ++  +     SV L E+       L  SL+Q++  P+ RT  GF S+I+K W+M+        N    S+  +  LFLLFLD  +QLL   P  FEF+E  L  L D
Sbjct:  333 PNIQEIQAAFVKLKQLCV---NEPFEETEEKWLSSLESTRWLEYVRAFLKHSAELVYILESQRLSVVLQEEEGRDLSCLVASLIQVMMDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEK-ESPLFLLFLDTTWQLLEQYPAAFEFSETYLAVLCD 489
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BLAST of Myotubularin related protein 12 vs. Ensembl Mouse
Match: Mtmr9 (myotubularin related protein 9 [Source:MGI Symbol;Acc:MGI:2442842])

HSP 1 Score: 75.8702 bits (185), Expect = 6.944e-14
Identity = 62/242 (25.62%), Postives = 102/242 (42.15%), Query Frame = 1 
Query:  748 PQVVYYSDHNDSCLI----VIDKSSGKKCSNSLKHISKTILGPKIKV--------VLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKA-----EFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSN---------AFYNSDGPKYS--LFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P + YY   N   ++     +  ++G++C    K I+ T+   K           V      +    + E + P  + + +S E+ ++L     K      E      +WL K     WL  +   L +  +  + +    +SV +             SL QII +P  RT  GF ++IE+ W+ +          + Y S   K+   +FLLFLDCV+Q+LR  P  FEFNE  LI L++
Sbjct:  186 PVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRGYLIDTRSLNVAQQARAKGGGFEQEAHYPQWRRIHKSIERYHVLQESLIKLVEACNEQTHNMDRWLGKLEASNWLTHIKEILTTACLAAQCIDREGASVLIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQSAYCSSKQKWEAPVFLLFLDCVWQILRQFPCSFEFNEHFLIMLFE 427
[Close]
BLAST of Myotubularin related protein 12 vs. UniProt/SwissProt
Match: sp|Q5FVM6|MTMRC_RAT (Myotubularin-related protein 12 OS=Rattus norvegicus OX=10116 GN=Mtmr12 PE=1 SV=2)

HSP 1 Score: 106.686 bits (265), Expect = 1.749e-22
Identity = 128/459 (27.89%), Postives = 188/459 (40.96%), Query Frame = 1 
Query:  454 FIITCYDFRVYSY----------NRI--SIYNKNDAIKFYQEIF-----RLVFETEDDRMKCDM-------WMKIGDEVLRDVYYKTV--NNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVI-------DKSSGKKCSNSLKHISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM-------------NSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
             +I C D RV  +           RI   I +   + K  + +F       V  T  D   C +       W    +     V YKTV  N   RV    +  Y VV P  L  +++K     G  +  +S HN S L+ +       D S+ +   + L  I KTI  P  ++V        +E+ S  +  + +E+  S+ K   L    + +EF   D KW S     GWL+++ RCL+    I++ +     +V L+E+       L  SLVQ++     RT  GF S+I+K W+M         N  + SD  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F               SLD   K +      DWS+ F  +    L N  Y+E+        PK+D        FK + R +     +S S   R FF
Sbjct:  141 LVIHCKDLRVLHFCLRYTKEEEVKRIVSGIIHHTQSPKLLKRLFLFSYAAAVHGTAADPRNCTVMFDTPKDWCWELERTKGSVKYKTVSVNEGYRV-CDRLPAYFVV-PTPLLEDDVKRFQGRGIPIWCWSCHNGSALLKMSALPKEQDDSALQIQKSFLDGIYKTIHRPPYEMV-------KTEDLSSNFL-SLQEIQSSYCKFKQLFLIDSSSEFWDTDVKWFSLLESSGWLDIIRRCLKRAIEIIECLEAQNMNVLLLEENASDLCCLLSSLVQVMMDAHCRTWTGFQSLIQKEWVMGGHSFLDRCNHLHQSDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGRESLDAQSKPLTLLTVWDWSVQFEPKAQTLLRNPLYVEK--------PKLDKGQRKGSRFK-HQRQLSLPLTQSKSSPKRGFF 580
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BLAST of Myotubularin related protein 12 vs. UniProt/SwissProt
Match: sp|Q5R989|MTMRC_PONAB (Myotubularin-related protein 12 OS=Pongo abelii OX=9601 GN=MTMR12 PE=2 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 4.726e-22
Identity = 125/457 (27.35%), Postives = 189/457 (41.36%), Query Frame = 1 
Query:  454 FIITCYDFRVYSY----------NRI--SIYNKNDAIKFYQEIFRLVFETE-------DDRMKCDMWMKIGD---EVLR---DVYYK--TVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLKHISKTILGPKIKVVLFHLN----CENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM-------------NSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
             II C DFRV+ +           RI   I +   A K  + +F   + T        D +    M+  + D   E+ R   ++ YK  +VN   +V  + +  Y VV P  L   N++     G  +  +S HN S L+ +  +  K+  + +  I K+ L    K +  H +     +  +  S F   + +E+  ++ K   L    N  EF   D KW S      WL+++ RCL+    I + M     +V L+E+       L  SLVQ++  P  RTR GF S+I+K W+M         N    +D  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F                 D   K +      DWS+ F  +    L N  Y+E+        PK+D        FK + R +     +S S   R FF
Sbjct:  139 LIIHCKDFRVFQFCLGYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKV-CERLPAYFVV-PTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMS-ALPKEQDDGILQIQKSFLDGIYKTI--HRSPYEIVKTEDVSSNFL--SLQEIQTAYSKFKQLFLTDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDANMGREGQDAQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEK--------PKLDKGQRKGMRFK-HQRQLSLPLTQSKSSPKRGFF 579
[Close]
BLAST of Myotubularin related protein 12 vs. UniProt/SwissProt
Match: sp|Q80TA6|MTMRC_MOUSE (Myotubularin-related protein 12 OS=Mus musculus OX=10090 GN=Mtmr12 PE=1 SV=2)

HSP 1 Score: 105.145 bits (261), Expect = 5.434e-22
Identity = 123/459 (26.80%), Postives = 186/459 (40.52%), Query Frame = 1 
Query:  454 FIITCYDFRVYSY----------NRI--SIYNKNDAIKFYQEIF-----RLVFETEDDRMKCDM-------WMKIGDEVLRDVYYKTV--NNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLK-------HISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM-------------NSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
             +I C D RV  +           RI   I +   + K  + +F       V  T  D   C +       W    +     V Y+TV  N   RV    +  Y VV P  L  ++++     G  +  +S HN S L+ +     ++   +L+        I KTI  P  ++V        +E+ S  +  + +E+  ++ K   L    N +EF   D KW S      WL+++ RCL+    I + +     +V L+E+       L  SLVQ++     RTR GF S+I+K W+M         N  + SD  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F               +LD   K +      DWS+ F  +    L N  Y+E+        PK+D        FK + R +     +S S   R FF
Sbjct:  140 LVIHCKDLRVLHFCLRYTKEEEVKRIVSGIIHHTQSPKLLKRLFLFSYAAAVHGTATDSRNCTVMFDTPKDWCWELERTKGSVKYRTVSVNEGYRVS-DRLPAYFVV-PTPLPEDDVRRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGALQVQKSFLDGIYKTIHRPPYEMV-------KTEDLSSNFL-SLQEIQSAYCKFKQLFLIDNSSEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECLEAQNVNVLLLEENASDLCCLLSSLVQVMMDAHCRTRTGFQSLIQKEWVMGGHSFLDRCNHLHQSDKEEVPIFLLFLDCVWQLVHQYPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGRENLDAQSKPLTLLTVWDWSVQFEPKAQTLLRNPLYVEK--------PKLDRGQQKGSRFK-HQRQLSLPLTQSKSSPKRGFF 579
[Close]
BLAST of Myotubularin related protein 12 vs. UniProt/SwissProt
Match: sp|Q9C0I1|MTMRC_HUMAN (Myotubularin-related protein 12 OS=Homo sapiens OX=9606 GN=MTMR12 PE=1 SV=2)

HSP 1 Score: 103.99 bits (258), Expect = 1.037e-21
Identity = 125/460 (27.17%), Postives = 188/460 (40.87%), Query Frame = 1 
Query:  454 FIITCYDFRVYSY----------NRI--SIYNKNDAIKFYQEIFRLVFETE-------DDRMKCDMWMKIGD---EVLR---DVYYK--TVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLK-------HISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM-------------NSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
             II C D RV+ +           RI   I +   A K  + +F   + T        D +    M+  + D   E+ R   ++ YK  +VN   +V  + +  Y VV P  L   N++     G  +  +S HN S L+ +     ++    L+        I KTI  P  ++V        +E+ S  +  + +E+  ++ K   L    N  EF   D KW S      WL+++ RCL+    I + M     +V L+E+       L  SLVQ++  P  RTR GF S+I+K W+M         N    +D  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F                 D   K +      DWS+ F  +    L N  Y+E+        PK+D        FK + R +     +S S   R FF
Sbjct:  139 LIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKV-CERLPAYFVV-PTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEIV-------KTEDLSSNFL-SLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEK--------PKLDKGQRKGMRFK-HQRQLSLPLTQSKSSPKRGFF 579
[Close]
BLAST of Myotubularin related protein 12 vs. UniProt/SwissProt
Match: sp|Q5U581|MTRAA_XENLA (Myotubularin-related protein 10-A OS=Xenopus laevis OX=8355 GN=mtmr10-a PE=2 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 7.654e-16
Identity = 56/161 (34.78%), Postives = 82/161 (50.93%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P+ +++  +F KL  LC       F + ++KWLS   +  WL  V   L+    +   +  S  SV L E+       L  SLVQ++  P+ RT  GF S+I+K W+MS        N    S+  +  LF+LFLDCV+QLL+  P  F+F E  L  L+D
Sbjct:  325 PSIQDIQAAFSKLRQLCV---NEPFDETEEKWLSSLENAQWLEFVRTFLKQAAELAYVLDFSRRSVVLQEEEGRDVSCLVASLVQLMLDPYFRTIVGFQSLIQKEWVMSAYPFLDRCNHLKRSEK-ESPLFVLFLDCVWQLLQQYPAAFQFTETYLTVLHD 481
[Close]
BLAST of Myotubularin related protein 12 vs. TrEMBL
Match: G3HIQ6 (Myotubularin-related protein 12 OS=Cricetulus griseus OX=10029 GN=I79_010532 PE=4 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 2.230e-20
Identity = 111/383 (28.98%), Postives = 162/383 (42.30%), Query Frame = 1 
Query:  628 VYYKTV--NNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLK-------HISKTILGPKIKVVLFH------LNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM-------------NSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
            V YKTV  N   R+    +  Y VV P  L   +++     G  +  +S HN S L+ +     ++   +L+        I KTI  P  ++V         L+ +  +N    YC         F++L+++    N  EF   D KW S      WL+++ RCL+    I + +     +V L+E+       L  SLVQ++  P  RTR GF S+I+K W+M         N    SD  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F               SLD   K +      DWS+ F  +    L N  Y+E+        PK+D        FK + R +     +S S   R FF
Sbjct:   19 VKYKTVRVNEGYRI-CDRLPAYFVV-PTPLLEEDVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGALQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQNA---YC--------KFKQLFLI---DNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECLEAQNMNVLLLEENASDLCCLLSSLVQVMMDPHCRTRTGFQSLIQKEWVMGCHSFLDRCNHLRQSDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETFLTVLSDSLYIPIFSTFFFNSPHQKDTNMGRESLDTQSKPLTLLTVWDWSVQFEPKAQTLLRNPLYVEK--------PKLDKGQRRGSRFK-HQRQLSLPLTQSKSSPKRGFF 376
[Close]
BLAST of Myotubularin related protein 12 vs. TrEMBL
Match: H0XAV2 (Myotubularin related protein 12 OS=Otolemur garnettii OX=30611 GN=MTMR12 PE=4 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 4.382e-20
Identity = 108/371 (29.11%), Postives = 159/371 (42.86%), Query Frame = 1 
Query:  640 TVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVI-------DKSSGKKCSNSLKHISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM-------------NSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
            +VN   +V  + +  Y VV P  LS  +++     G  +  +S HN S L+ +       D    +   + L  I KTI  P  ++V        +E+ S  +  + +E+  ++ K   L    N AEF   D KW S      WL+++ RCL+    I + M     +V L+E+       L  SLVQ++  P  RTR GF S+++K W+M         N    SD  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F               S D   K +      DWS+ F  +    L N  Y+E+        PK+D        FK + R +     +S S   R FF
Sbjct:  228 SVNEGYKV-CERLPAYFVV-PTPLSEEDVQRFQGHGIPIWCWSCHNGSALLKMSALPREQDDGILQTQKSFLDGIYKTIHRPPYEIV-------KTEDLSSNFL-SLQEIQAAYSKFKQLFLIDNSAEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQVMMDPHYRTRIGFQSLVQKEWVMGGHCFLDRCNHLRQSDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNVGRESQDIQSKPLSLLTVWDWSVQFEPKAQTLLKNPLYVEK--------PKLDKGQRKGTRFK-HQRQLSLPLTQSKSSPKRGFF 579
[Close]
BLAST of Myotubularin related protein 12 vs. TrEMBL
Match: A0A0N5A9U2 (Myotubularin phosphatase domain-containing protein OS=Syphacia muris OX=451379 PE=4 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 5.499e-20
Identity = 82/265 (30.94%), Postives = 118/265 (44.53%), Query Frame = 1 
Query:  934 TNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIM------SNAFY-------NSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFIL--APSGFMNS------LDYDFKGIDWSLYFVDQVLECLDNYYYLEESFDS-----CLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFFM 1650
            TN ++   FEKL   C+  +  +F +R+K+W S     GW  LV +CL   + I+K+M +   SV + +        +  SLVQ+    F RT NG   +IEK WI        N F+           P  + FLLFLDC+YQLLR  P  FE+++ MLI L+DL ++  AP+   NS      L+ +      S Y+  +      N  Y             L  P  + +D   FW   Y RW+    I+ G    R   M
Sbjct:  345 TNTKISSCFEKLREFCSFEDLTQFNEREKEWYSLLDATGWCALVFQCLSFVRNILKTMFDGQRSVIITDDDGYNASAIVSSLVQVCADGFYRTINGLNMLIEKEWIALGHPFGVNIFHCTLSARVQPSSPCTASFLLFLDCLYQLLRMYPSSFEYSQHMLIALWDLCVMGFAPALVCNSVSDQTALERNVSVFPLSQYYSSKYCIMFTNVAYSANDLLGIGNLPTLIEPSANPVDV-EFWSDCYLRWVSPASIQEGGNITRDVTM 608
[Close]
BLAST of Myotubularin related protein 12 vs. TrEMBL
Match: A0A2I2YTX3 (Myotubularin related protein 12 OS=Gorilla gorilla gorilla OX=9595 PE=4 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 1.868e-19
Identity = 126/460 (27.39%), Postives = 188/460 (40.87%), Query Frame = 1 
Query:  454 FIITCYDFRVYSY----------NRI--SIYNKNDAIKFYQEIFRLVFETE-------DDRMKCDMWMKIGD---EVLR---DVYYK--TVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLK-------HISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM-------------NSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
             II C D RV+ +           RI   I +   A K  + +F   + T        D +    M+  + D   E+ R   ++ YK  +VN   +V  + +  Y VV P  L   N++     G  +  +S HN S L+ +     ++    L+        I KTI  P  +VV        +E+ S  +  + +E+  ++ K   L    N  EF   D KW S      WL+++ RCL+    I + M     +V L+E+       L  SLVQ++  P  RTR GF S+I+K W+M         N    +D  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F                 D   K +      DWS+ F  +    L N  Y+E+        PK+D        FK + R +     +S S   R FF
Sbjct:  139 LIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDPKNHTVMFDTLKDWCWELERTKGNMKYKAVSVNEGYKV-CERLPAYFVV-PTPLPEENVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGILQIQKSFLDGIYKTIHRPPYEVV-------KTEDLSSNFL-SLQEIQTAYSKFKQLFLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEK--------PKLDKGQRKGMRFK-HQRQLSLPLTQSKSSPKRGFF 579
[Close]
BLAST of Myotubularin related protein 12 vs. TrEMBL
Match: A0A1U7QS49 (myotubularin-related protein 12 OS=Mesocricetus auratus OX=10036 GN=Mtmr12 PE=4 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 2.111e-19
Identity = 109/383 (28.46%), Postives = 162/383 (42.30%), Query Frame = 1 
Query:  628 VYYKTV--NNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLK-------HISKTILGPKIKVVLFH------LNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFM-------------NSLDYDFKGI------DWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFF 1647
            V YKTV  N   R+    +  Y VV P  L   +++     G  +  +S HN S L+ +     ++   +L+        I KTI  P  ++V         L+ +  +N    YC         F++L+++    N  EF   D KW S      WL+++ RCL+    I + +     +V L+E+       L  SLVQ++  P  RTR GF S+I+K W+M         N    SD  +  +FLLFLDCV+QL+   P  FEF E  L  L D L+I   S F               +LD   K +      DWS+ F  +    L N  Y+E+        PK++        FK + R +     +S S   R FF
Sbjct:  222 VKYKTVRVNEGYRI-CDRLPAYFVV-PTPLLEEDVQRFQGHGIPIWCWSCHNGSALLKMSALPKEQDDGTLQIQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQNA---YC--------KFKQLFLI---DNSTEFWDTDVKWFSLLESSSWLDIIRRCLKKAIEITECLEAQNVNVLLLEENASDLCCLLSSLVQVMMDPHCRTRTGFQSLIQKEWVMGCHSFLDRCNHLRQSDKEEVPVFLLFLDCVWQLVHQHPPAFEFTETFLTVLSDSLYIPIFSTFFFNSPHQKDTNMGRENLDTQSKPLTLLTVWDWSVQFEPKAQTLLRNPLYVEK--------PKLEKGQRKGSRFK-HQRQLSLPLTQSKSSPKRGFF 579
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Cavefish
Match: mtmr10 (myotubularin related protein 10 [Source:NCBI gene;Acc:555239])

HSP 1 Score: 81.6481 bits (200), Expect = 1.440e-15
Identity = 50/161 (31.06%), Postives = 79/161 (49.07%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P  +E+  +  KL  +C       F++ ++KWLS      W+  V   L+    ++  +    +SV L E+       +  SLVQ++C P  R+  GF  +++K W+M+        N    +D  +  LFLLFL+CV+QL+   P  FEF E  LI L D
Sbjct:  295 PNIQEIQTALVKLRQICV---IDPFEESEEKWLSSMESSRWMEYVRSFLKHAVEVVYMLEGKQASVILQEEEDRDLSCVISSLVQVMCDPHCRSLAGFQGLVQKEWVMAGHRFLDRCNHLKKNDKEESPLFLLFLNCVWQLMEQYPAAFEFTEMYLIMLSD 452
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Cavefish
Match: mtmr12 (myotubularin related protein 12 [Source:NCBI gene;Acc:103022157])

HSP 1 Score: 79.7221 bits (195), Expect = 4.757e-15
Identity = 48/167 (28.74%), Postives = 85/167 (50.90%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS-NAFYN-------------SDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            PT +++ +S+ K        N  +F   D KW S   + GW++++ +CLQ    +++ + +  +++ +ME+       +  SLVQI+  P  RT  GF  +++K W+   +AF +             S  P   +FLLFL+CV+QL++     F+F+E  L  L D
Sbjct:  311 PTVQDIQQSYAKFKQFFLIDNSTDFWVSDVKWFSSVENTGWMDIIRKCLQKAVEVVECLEKENTNILIMEEEGTDLCCVISSLVQIMLDPHYRTLTGFQGLVQKEWVAGCHAFLDRCNHLCQKDKECQSPSP---IFLLFLECVWQLVQQHSPAFQFSETYLTVLSD 474
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Cavefish
Match: mtmr11 (myotubularin related protein 11 [Source:NCBI gene;Acc:103025879])

HSP 1 Score: 77.7962 bits (190), Expect = 2.237e-14
Identity = 48/166 (28.92%), Postives = 77/166 (46.39%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFILA 1404
            P+  +L  +  +L  LC     +     D KWLS      WL+ +  CL+    +   +     +V L E        +  SLVQ++C    RT  GF ++++K W+++        N   +SD  +  +FLLFLDCV+QL    P  F+  E+ L+ L+D   L 
Sbjct:  296 PSPADLQLAHTRLRTLCLGDISSSVSVPDDKWLSSLEGTHWLDYIRCCLRKAAEVACLLRRGHLTVVLQEPEDRDMNCVVSSLVQVMCDQHCRTVAGFQALVQKEWVVAGHRFLSRINYHRDSDKEEAPIFLLFLDCVWQLWAQFPARFQLTEDFLLALHDSLHLP 461
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Cavefish
Match: mtmr11 (myotubularin related protein 11 [Source:NCBI gene;Acc:103025879])

HSP 1 Score: 77.7962 bits (190), Expect = 2.237e-14
Identity = 48/166 (28.92%), Postives = 77/166 (46.39%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFILA 1404
            P+  +L  +  +L  LC     +     D KWLS      WL+ +  CL+    +   +     +V L E        +  SLVQ++C    RT  GF ++++K W+++        N   +SD  +  +FLLFLDCV+QL    P  F+  E+ L+ L+D   L 
Sbjct:  296 PSPADLQLAHTRLRTLCLGDISSSVSVPDDKWLSSLEGTHWLDYIRCCLRKAAEVACLLRRGHLTVVLQEPEDRDMNCVVSSLVQVMCDQHCRTVAGFQALVQKEWVVAGHRFLSRINYHRDSDKEEAPIFLLFLDCVWQLWAQFPARFQLTEDFLLALHDSLHLP 461
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Cavefish
Match: mtmr11 (myotubularin related protein 11 [Source:NCBI gene;Acc:103025879])

HSP 1 Score: 77.7962 bits (190), Expect = 2.334e-14
Identity = 48/166 (28.92%), Postives = 77/166 (46.39%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFILA 1404
            P+  +L  +  +L  LC     +     D KWLS      WL+ +  CL+    +   +     +V L E        +  SLVQ++C    RT  GF ++++K W+++        N   +SD  +  +FLLFLDCV+QL    P  F+  E+ L+ L+D   L 
Sbjct:  317 PSPADLQLAHTRLRTLCLGDISSSVSVPDDKWLSSLEGTHWLDYIRCCLRKAAEVACLLRRGHLTVVLQEPEDRDMNCVVSSLVQVMCDQHCRTVAGFQALVQKEWVVAGHRFLSRINYHRDSDKEEAPIFLLFLDCVWQLWAQFPARFQLTEDFLLALHDSLHLP 482
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Sea Lamprey
Match: sbf1 (SET binding factor 1 [Source:ZFIN;Acc:ZDB-GENE-040718-139])

HSP 1 Score: 68.1662 bits (165), Expect = 5.641e-12
Identity = 57/193 (29.53%), Postives = 93/193 (48.19%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWI--------MSNAFYNSDGPKYS-LFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFILAPSGFMNS--LDYDFKGIDWSLYFVDQ 1476
            P  + +  SF+KL   C P        +D  +     +  WL  + R LQ  +++++ +    S +  +E+G+     L  S+VQ++  PF RT +GF  ++EK WI         SN    S G   + LFL FLDCV+Q+    P  FEFN+  L FL   F+   S    +  LD D++ I+  + + ++
Sbjct: 1375 PDVRAVKASFKKLLRACVPSTSPS---QDMTFYKSLEESEWLQQIQRLLQLAELVVELLDGGSSVMVSLEEGWDITTQLV-SMVQLLSDPFYRTLDGFRLLVEKEWISFGHRFSHRSNQTLASQGSGLAPLFLQFLDCVHQVHNQFPTEFEFNQYYLKFLAYHFV---SNRFRTFLLDSDYERIEMGMMYEEK 1560
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Sea Lamprey
Match: mtm1 (myotubularin 1 [Source:ZFIN;Acc:ZDB-GENE-051113-128])

HSP 1 Score: 65.4698 bits (158), Expect = 2.143e-11
Identity = 40/139 (28.78%), Postives = 64/139 (46.04%), Query Frame = 1 
Query: 1015 DKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGW----LFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFY----------NSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            + +WLS      WL  +   L     I + +    +SV +    + + GW       +L  ++  P+ RT  GF  ++EK W+ S   +          ++D  +  +FL F+DCV+QL +  P  FEFNE  LI L D
Sbjct:  319 ESRWLSSLEATHWLEHIKAVLSGAIQIAEKLELERTSVLV----HCSDGWDRTAQLSALAMLLLDPYYRTLRGFEVLVEKEWVSSGHKFQQRVGHGDKNHADSDRSPIFLQFVDCVWQLTKQFPTAFEFNERFLIMLLD 453
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Sea Lamprey
Match: mtmr9 (myotubularin related protein 9 [Source:ZFIN;Acc:ZDB-GENE-040724-223])

HSP 1 Score: 59.3066 bits (142), Expect = 1.886e-9
Identity = 69/265 (26.04%), Postives = 102/265 (38.49%), Query Frame = 1 
Query:  727 KDNFEFGPQVVYYSDHND----SCLIVIDKSSGKKCSNSLKHISKTILGPK-----IKVVLFHLNCENSENKSEFYCPT---------NKE------LIESFEKLYILCT-PRNKAEFKKRDKKWLSKQADCGWLN-----LVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSN----------AFYN----SDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            + N  F P + YY   N      C   +  S GK+C +  K ++  +LGP      I     H+  + +  K   Y P          NK       + +SF KL   C  P +  +      +WLSK     WL      L   CL +  +      E  S +     G  +      +L Q+I     RT  GF +++E+ W+ +           AF N     + P    FLLFLDC  Q+ R  P  FEF E  L+ L++
Sbjct:  180 RQNGRF-PVLSYYHKTNGMVMMRCSQPLTGSGGKRCKDDEKLVN-AVLGPGKRGYIIDTRSLHI-AQQARAKGGGYEPEAHYPQWRRINKSIERYNLMQDSFIKLVEACNDPSHNMD------RWLSKLEASNWLGHIKDILTAACLAAQCLDSARTREGASVLVHGSDGTDS-TLQVSALAQVILDQDCRTLRGFQALVEREWLQAGHPFQERCSRSAFANVKPRQEAPS---FLLFLDCCQQIQRQFPCSFEFGERFLVLLFE 431
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010382.1 (pep scaffold:Pmarinus_7.0:GL482471:369374:413667:1 gene:ENSPMAG00000009395.1 transcript:ENSPMAT00000010382.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.6102 bits (135), Expect = 1.845e-8
Identity = 47/158 (29.75%), Postives = 67/158 (42.41%), Query Frame = 1 
Query:  955 SFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGS------LVQIICQPFVRTRNGFLSMIEKNWIM--------SNAFYNSDGPKYS-LFLLFLDCVYQLLRSSPFLFEFNEEMLIFL 1383
            SF KL   C P + A        +L+      WL  V   +    I++ S+  +  S  + E           S      LVQ++  PF RT +GF  +IEK W+         SN         ++ +FL FLDCV+Q+    P  FEFN+  L FL
Sbjct: 1201 SFRKLLHACCP-SSAPTDGGSSAFLTALEQSEWLPQVPSIVFRDAIMVHSIENASGSCQICEANLDCPPPPPCSASQVVSLVQLLSDPFYRTLDGFRLLIEKEWLAFGHRFGQRSNMGAGGQSANFTPVFLQFLDCVHQVQYQFPTEFEFNDYYLRFL 1357
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002170.1 (pep scaffold:Pmarinus_7.0:GL484749:1247:6808:1 gene:ENSPMAG00000001972.1 transcript:ENSPMAT00000002170.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.447 bits (119), Expect = 2.882e-7
Identity = 29/79 (36.71%), Postives = 42/79 (53.16%), Query Frame = 1 
Query: 1174 SLVQIICQPFVRTRNGFLSMIEKNWI-------MSNAFYNSDGPKYS-LFLLFLDCVYQLLRSSPFLFEFNEEMLIFLY 1386
            S+ +I+  P+ RT  GFL +IEK WI           F   D  + S +FL  L+CV+QL    P  FEF+E +L  ++
Sbjct:   26 SVAEILLDPYYRTLRGFLVLIEKEWISFGHKFSQRCGFVEGDAREVSPVFLQLLECVWQLSLQFPCAFEFSERLLTSVH 104
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Nematostella
Match: EDO37565 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFD9])

HSP 1 Score: 67.3958 bits (163), Expect = 1.035e-11
Identity = 47/170 (27.65%), Postives = 76/170 (44.71%), Query Frame = 1 
Query:  928 CPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFY-----------NSDGPKY-----SLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            CP+ ++L +S+ ++  LC       F   D  WLS   +  WL  V   + +   + K++ E    V + E        +  SL Q++   + R   GF ++I+K W++    +            SD  K       +FL FLDCVYQL+   P  FEF+E  L+ + D
Sbjct:  291 CPSIQQLSQSYLRVRELCVLDTTKNFWSIDPHWLSSLDNSRWLASVRTSISTAVDVCKAVCEEGRPVIVKEASGRDLVLVVCSLAQLMLDQYYRNIRGFQTLIQKMWVLGGHPFMKRCGHIKPNEKSDADKQENEESPVFLHFLDCVYQLITQFPSEFEFSETYLLGMLD 460
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Nematostella
Match: EDO33774 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR96])

HSP 1 Score: 65.4698 bits (158), Expect = 4.675e-11
Identity = 46/162 (28.40%), Postives = 73/162 (45.06%), Query Frame = 1 
Query:  946 LIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWI--------------MSNAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            LI+S  KL   C  +N +        +LS+   CGW++ +   L +   +   +      V + +           SL Q+I  P  RT  GF S++++ WI               S+  Y   GP   +FLLFLDCV+Q+ +  P  FEF++  LI L++
Sbjct:  276 LIDSVCKLMEACFDQNLSM-----NAYLSRLESCGWMDQIQAVLGTACYVAHCLHTDGIPVLVHDGAGLDATLQVTSLSQVILDPDCRTVRGFQSLVDREWIRGGHPFSNRCTRVGFSSTKYKGQGP---VFLLFLDCVWQIYQQFPCSFEFHDSFLICLFE 429
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Nematostella
Match: EDO44480 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVM7])

HSP 1 Score: 65.0846 bits (157), Expect = 5.712e-11
Identity = 67/257 (26.07%), Postives = 108/257 (42.02%), Query Frame = 1 
Query:  952 ESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGW----LFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFYN----------SDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD-LFILAPSGFMNSLDY-----DFKGIDWSLY-FVDQVLECLDNYYYLEESFDSCLF-VPKVDVMDFGSFWFKMYARWIPYVQI-ESGSMSVRHFFMV 1653
            ES  KL  +C P         D  WL+   +  WL+ +   +     I  ++    +SV +    + + GW       +L  ++  P+ RT  GF  +IEK W+     +N          +D  +  +FL F+DCV+Q+ R  P  FEFNE  LI + D L+      F+ + +      D K    SL+ +++  +    N  Y        LF VP +  ++    W + Y RW P +Q  ES     R  F +
Sbjct:  321 ESLRKLKDICFPNID------DTHWLTNLENTKWLDHIKMIMAGAVRIADAVDRCRTSVVV----HCSDGWDRTPQLTALAMLLMDPYYRTIIGFEVLIEKEWLSFGHKFNQRYGHGDKNHADDQRSPVFLQFIDCVWQVTRQFPCAFEFNETFLITILDHLYSCMFGTFLYNSESQREKEDVKTRTTSLWSYINTSMMEFKNPLYAPYLHQHVLFPVPSLRRLE---LWTRYYIRWNPRMQAQESEEQRNRDLFFL 564
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Nematostella
Match: EDO34710 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNP0])

HSP 1 Score: 60.077 bits (144), Expect = 2.423e-9
Identity = 41/125 (32.80%), Postives = 65/125 (52.00%), Query Frame = 1 
Query: 1051 WLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGW----LFGSLVQIICQPFVRTRNGFLSMIEKNWIMSN-------AFYNSDGPKYS-LFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            WL  +   L ++  I K+++   +SV +    + + GW       SL  II  P+ RT +GF  +IEK W+              SD  ++S +FL FL+ ++QLL+  PF F+FNE  L+ L+D
Sbjct:  311 WLKHIKNILDTSVFIAKAVAMEKASVLV----HCSDGWDRTAQTCSLASIILDPYYRTIHGFQVLIEKEWLSFGHKFTDRCGLLQSDQKEFSPVFLQFLESIWQLLQQFPFSFQFNERFLLTLHD 431
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Nematostella
Match: EDO48708 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIH6])

HSP 1 Score: 55.0694 bits (131), Expect = 1.953e-8
Identity = 43/160 (26.88%), Postives = 71/160 (44.38%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWI-MSNAFYNSDG------PKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            P    + +S ++L  +C   ++       KKWLS      WL  +   L+    I + + +  S++     G+         L Q++  P+ RT  GF  +IEK WI   + F +  G       +  +FL FLDCV+Q+ +  P  F+F    L+ L D
Sbjct:   12 PNIHAVRDSLDRLQAVCESSSQ-------KKWLSHLESTQWLAYIAAILKGATTIARFVDKGVSTLVHCSDGWDRTS-QLTLLAQLLLDPYYRTFTGFQVLIEKEWISFGHRFRDRLGHPTCPSQRSPIFLQFLDCVWQVHKQFPSAFQFTANYLLKLAD 163
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Medaka
Match: mtmr11 (myotubularin related protein 11 [Source:NCBI gene;Acc:101164676])

HSP 1 Score: 80.8777 bits (198), Expect = 2.530e-15
Identity = 56/187 (29.95%), Postives = 89/187 (47.59%), Query Frame = 1 
Query:  868 IKVVLFHLNCENS-----ENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            +++VLF   C+NS     E   E   P++ +L  S  +L  LC           D KWLS      WL+ V  CL+    +   +     +V L E        +  SLVQ++  P  R+++GF S+++K W+M+        N   ++D  +  +FLLFLDCV+QL    P  F+   + L+ L+D
Sbjct:  270 LEMVLF--GCQNSLCVVVELGDELPSPSDIQLAHS--RLRTLCLGDVSTSVSVPDDKWLSTLESTHWLDHVRLCLRKASEVACLLRSGHLTVALQEPEDRDMSCVVSSLVQVMSDPHCRSQHGFQSLVQKEWVMAGHRFYSRINYHRDNDKEEAPVFLLFLDCVWQLWFQFPSRFQLTGDFLLALHD 452
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Medaka
Match: mtmr11 (myotubularin related protein 11 [Source:NCBI gene;Acc:101164676])

HSP 1 Score: 80.4925 bits (197), Expect = 2.855e-15
Identity = 56/187 (29.95%), Postives = 89/187 (47.59%), Query Frame = 1 
Query:  868 IKVVLFHLNCENS-----ENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            +++VLF   C+NS     E   E   P++ +L  S  +L  LC           D KWLS      WL+ V  CL+    +   +     +V L E        +  SLVQ++  P  R+++GF S+++K W+M+        N   ++D  +  +FLLFLDCV+QL    P  F+   + L+ L+D
Sbjct:  297 LEMVLF--GCQNSLCVVVELGDELPSPSDIQLAHS--RLRTLCLGDVSTSVSVPDDKWLSTLESTHWLDHVRLCLRKASEVACLLRSGHLTVALQEPEDRDMSCVVSSLVQVMSDPHCRSQHGFQSLVQKEWVMAGHRFYSRINYHRDNDKEEAPVFLLFLDCVWQLWFQFPSRFQLTGDFLLALHD 479
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Medaka
Match: mtmr11 (myotubularin related protein 11 [Source:NCBI gene;Acc:101164676])

HSP 1 Score: 80.4925 bits (197), Expect = 3.069e-15
Identity = 56/187 (29.95%), Postives = 89/187 (47.59%), Query Frame = 1 
Query:  868 IKVVLFHLNCENS-----ENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            +++VLF   C+NS     E   E   P++ +L  S  +L  LC           D KWLS      WL+ V  CL+    +   +     +V L E        +  SLVQ++  P  R+++GF S+++K W+M+        N   ++D  +  +FLLFLDCV+QL    P  F+   + L+ L+D
Sbjct:  301 LEMVLF--GCQNSLCVVVELGDELPSPSDIQLAHS--RLRTLCLGDVSTSVSVPDDKWLSTLESTHWLDHVRLCLRKASEVACLLRSGHLTVALQEPEDRDMSCVVSSLVQVMSDPHCRSQHGFQSLVQKEWVMAGHRFYSRINYHRDNDKEEAPVFLLFLDCVWQLWFQFPSRFQLTGDFLLALHD 483
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Medaka
Match: mtmr10 (myotubularin related protein 10 [Source:NCBI gene;Acc:101161383])

HSP 1 Score: 79.337 bits (194), Expect = 7.817e-15
Identity = 50/161 (31.06%), Postives = 81/161 (50.31%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            PT +E+  +F K+  +C       F++ +++WLS   +  WL+ V   L+ +  I+  +     SV L E+       +  SLVQ++  P  R+  GF S+++K W+M+        N    +D  +  LF LFLDCV+Q++   P  FEF E  L  L D
Sbjct:  323 PTIQEIQSAFAKIRQICV---LDPFEETEERWLSSIENSRWLDYVRVFLRQSAEIVYLLDGRNVSVILQEEEDRDLNCVVSSLVQLMLDPHYRSLTGFQSLVQKEWVMAGHRFLDRCNHLKKNDREECPLFTLFLDCVWQMMNQYPAAFEFTEAYLTVLSD 480
[Close]
BLAST of Myotubularin related protein 12 vs. Ensembl Medaka
Match: mtmr10 (myotubularin related protein 10 [Source:NCBI gene;Acc:101161383])

HSP 1 Score: 79.337 bits (194), Expect = 7.817e-15
Identity = 50/161 (31.06%), Postives = 81/161 (50.31%), Query Frame = 1 
Query:  931 PTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS--------NAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            PT +E+  +F K+  +C       F++ +++WLS   +  WL+ V   L+ +  I+  +     SV L E+       +  SLVQ++  P  R+  GF S+++K W+M+        N    +D  +  LF LFLDCV+Q++   P  FEF E  L  L D
Sbjct:  323 PTIQEIQSAFAKIRQICV---LDPFEETEERWLSSIENSRWLDYVRVFLRQSAEIVYLLDGRNVSVILQEEEDRDLNCVVSSLVQLMLDPHYRSLTGFQSLVQKEWVMAGHRFLDRCNHLKKNDREECPLFTLFLDCVWQMMNQYPAAFEFTEAYLTVLSD 480
[Close]
BLAST of Myotubularin related protein 12 vs. Planmine SMEST
Match: SMESG000019399.1 (SMESG000019399.1)

HSP 1 Score: 1117.84 bits (2890), Expect = 0.000e+0
Identity = 560/566 (98.94%), Postives = 562/566 (99.29%), Query Frame = 1 
Query:   88 MNENSPNKALAVLYEPIELQSHFNYKKKSFIDKLRISNPNSKDSNSDTRFTEGILIIDLSNKQLLFRPYESIPSPDLIYYQENFHKKLTIQVNNIKNIMFLNKNNEYVTFKXXXXXXXXXXXFIITCYDFRVYSYNRISIYNKNDAIKFYQEIFRLVFETEDDRMKCDMWMKIGDEVLRDVYYKTVNNSIRVRFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLKHISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFILAPSGFMNSLDYDFKGIDWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFFMVVNLNLENLVYTNYPFSLNYDKITMNSDYNNIDDTRSINTLGSDD 1785
            MNENSPNKALAVLYEPIELQSHFNYKKKSFIDKLRISNPNSKDSNSDTRFTEGILIIDLSNKQLLFRPYESIPSPDLIYYQENFHKKLTIQVNNIKNIMFLNKNNEYVTFKSSSSIVKSYHSFIITCYDFRVYSYNRISIYNKNDAIKFYQEIFRLVFETEDDRMKCDMWM IGDEVLRDVYYKTVNNSIRV+FQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKC NSLKHISKTILGPKIK VLFHLNCE+SENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFILAPSGFMNSLDYDFKGIDWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFFMVVNL LENLVYTNYPFSLNYDKITMNSDYNNIDDTRSINTLGSDD
Sbjct:    1 MNENSPNKALAVLYEPIELQSHFNYKKKSFIDKLRISNPNSKDSNSDTRFTEGILIIDLSNKQLLFRPYESIPSPDLIYYQENFHKKLTIQVNNIKNIMFLNKNNEYVTFKSSSSIVKSYHSFIITCYDFRVYSYNRISIYNKNDAIKFYQEIFRLVFETEDDRMKCDMWMNIGDEVLRDVYYKTVNNSIRVKFQSIKKYLVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCLNSLKHISKTILGPKIKFVLFHLNCESSENKSEFYCPTNKELIESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFILAPSGFMNSLDYDFKGIDWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMYARWIPYVQIESGSMSVRHFFMVVNLKLENLVYTNYPFSLNYDKITMNSDYNNIDDTRSINTLGSDD 566
[Close]
BLAST of Myotubularin related protein 12 vs. Planmine SMEST
Match: SMESG000072462.1 (SMESG000072462.1)

HSP 1 Score: 62.7734 bits (151), Expect = 5.617e-10
Identity = 43/163 (26.38%), Postives = 73/163 (44.79%), Query Frame = 1 
Query:  952 ESFEKLYILCTPRNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIM-----------------SNAFYNSDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYD 1389
            ES  KL  LC P      K  +  W     +  WLN + + L  + ++ + ++   S +     G+     +  SL Q++  P+ RT  GF ++I+K W++                 S +  +    +  +FL F+DCV+Q+ +     FEFNE+ LI L D
Sbjct:  306 ESMRKLADLCYP------KPDNSNWHKALEETKWLNYIRQILLGSLMVAEKINSQRSVLVHCSDGWDRTAQI-TSLPQLMLDPYFRTIRGFQTLIDKEWLLMGHKISQRTGGLTEEFGSTSSTSQKSERAPIFLQFIDCVWQITQQFLAAFEFNEQFLIDLMD 461
[Close]
BLAST of Myotubularin related protein 12 vs. Planmine SMEST
Match: SMESG000007673.1 (SMESG000007673.1)

HSP 1 Score: 62.003 bits (149), Expect = 9.587e-10
Identity = 41/139 (29.50%), Postives = 76/139 (54.68%), Query Frame = 1 
Query: 1021 KWLSKQADCGWLNLVNRCLQSTKIIMKSM-SESCSSVFLMEQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMS-NAFYN----------------SDGPKYSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFL 1383
            +++SK  +  WL+ V + L  ++ +  ++ S+S + + + + G+  +  +  SLVQ+I     RT  GF +++++ WI   + FY+                ++  +  +FLLFLDCV+Q+L+ +P  FEFNE  LI L
Sbjct:  270 RYISKLENSQWLDRVRQMLFVSRFVAHALVSQSSNYIVVGDTGF-DFELIITSLVQVILHSDARTIRGFEALVDREWIQGGHPFYDRCKHQIVTSKAINPNPTNEIESPVFLLFLDCVWQILQFNPTSFEFNELFLICL 407
[Close]
BLAST of Myotubularin related protein 12 vs. Planmine SMEST
Match: SMESG000032817.1 (SMESG000032817.1)

HSP 1 Score: 60.4622 bits (145), Expect = 3.658e-9
Identity = 42/140 (30.00%), Postives = 70/140 (50.00%), Query Frame = 1 
Query: 1003 FKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGW----LFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFYNS--------DGPKYS-LFLLFLDCVYQLLRSSPFLFEFNEEMLIFL 1383
            F    + W +   +  WL  +++ L+S   I ++++E   SV +    + + GW       SL QI+   F RT  GF  +IE+ WI     ++         D  ++S +F+ +LDC++QL+R  P  FEFNE  L+ L
Sbjct:  274 FSMNGENWFTSIENSCWLKYLSKLLKSACDIARALNEDGRSVII----HCSDGWDRTPQLTSLSQILLDDFYRTIKGFKVLIEREWIHFGHKFSDRCGFNKSVDNKEWSPIFVQWLDCIHQLIRQYPCYFEFNETFLVKL 409
[Close]
BLAST of Myotubularin related protein 12 vs. Planmine SMEST
Match: SMESG000032817.1 (SMESG000032817.1)

HSP 1 Score: 60.4622 bits (145), Expect = 3.771e-9
Identity = 42/140 (30.00%), Postives = 70/140 (50.00%), Query Frame = 1 
Query: 1003 FKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLMEQGYPTWGW----LFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFYNS--------DGPKYS-LFLLFLDCVYQLLRSSPFLFEFNEEMLIFL 1383
            F    + W +   +  WL  +++ L+S   I ++++E   SV +    + + GW       SL QI+   F RT  GF  +IE+ WI     ++         D  ++S +F+ +LDC++QL+R  P  FEFNE  L+ L
Sbjct:  306 FSMNGENWFTSIENSCWLKYLSKLLKSACDIARALNEDGRSVII----HCSDGWDRTPQLTSLSQILLDDFYRTIKGFKVLIEREWIHFGHKFSDRCGFNKSVDNKEWSPIFVQWLDCIHQLIRQYPCYFEFNETFLVKL 441
The following BLAST results are available for this feature:
BLAST of Myotubularin related protein 12 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MTMR122.159e-2227.17myotubularin related protein 12 [Source:HGNC Symbo... [more]
MTMR121.806e-2126.11myotubularin related protein 12 [Source:HGNC Symbo... [more]
MTMR102.285e-1634.16myotubularin related protein 10 [Source:HGNC Symbo... [more]
MTMR105.512e-1634.16myotubularin related protein 10 [Source:HGNC Symbo... [more]
MTMR101.486e-1530.13myotubularin related protein 10 [Source:HGNC Symbo... [more]
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BLAST of Myotubularin related protein 12 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Y48G1C.102.512e-1528.24pep chromosome:WBcel235:I:81203:91020:1 gene:WBGen... [more]
Y48G1C.102.512e-1528.24pep chromosome:WBcel235:I:81193:90957:1 gene:WBGen... [more]
Y48G1C.102.512e-1528.24pep chromosome:WBcel235:I:81193:91020:1 gene:WBGen... [more]
mtm-96.464e-1227.81Myotubularin-related protein 9 [Source:UniProtKB/... [more]
mtm-98.125e-1227.81Myotubularin-related protein 9 [Source:UniProtKB/... [more]
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BLAST of Myotubularin related protein 12 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG50269.704e-1525.79gene:FBgn0035945 transcript:FBtr0301141[more]
CG50269.704e-1525.79gene:FBgn0035945 transcript:FBtr0076515[more]
CG50269.704e-1525.79gene:FBgn0035945 transcript:FBtr0076516[more]
CG144112.904e-1429.82gene:FBgn0030582 transcript:FBtr0300433[more]
CG144112.904e-1429.82gene:FBgn0030582 transcript:FBtr0300432[more]
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BLAST of Myotubularin related protein 12 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtmr123.869e-1529.63myotubularin related protein 12 [Source:NCBI gene;... [more]
mtmr124.111e-1529.63myotubularin related protein 12 [Source:NCBI gene;... [more]
mtmr104.306e-1531.68myotubularin related protein 10 [Source:NCBI gene;... [more]
mtmr115.374e-1429.81myotubularin related protein 11 [Source:ZFIN;Acc:Z... [more]
mtmr115.374e-1429.81myotubularin related protein 11 [Source:ZFIN;Acc:Z... [more]
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BLAST of Myotubularin related protein 12 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hoxa131.073e-2129.13homeobox A13 [Source:Xenbase;Acc:XB-GENE-479980][more]
nrip36.996e-2024.82nuclear receptor interacting protein 3 [Source:Xen... [more]
nrip31.040e-1825.21nuclear receptor interacting protein 3 [Source:Xen... [more]
nrip31.222e-1825.56nuclear receptor interacting protein 3 [Source:Xen... [more]
nrip31.297e-1825.91nuclear receptor interacting protein 3 [Source:Xen... [more]
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BLAST of Myotubularin related protein 12 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mtmr127.769e-2326.80myotubularin related protein 12 [Source:MGI Symbol... [more]
Mtmr125.495e-2227.48myotubularin related protein 12 [Source:MGI Symbol... [more]
Mtmr129.029e-1931.28myotubularin related protein 12 [Source:MGI Symbol... [more]
Mtmr101.305e-1433.54myotubularin related protein 10 [Source:MGI Symbol... [more]
Mtmr96.944e-1425.62myotubularin related protein 9 [Source:MGI Symbol;... [more]
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BLAST of Myotubularin related protein 12 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5FVM6|MTMRC_RAT1.749e-2227.89Myotubularin-related protein 12 OS=Rattus norvegic... [more]
sp|Q5R989|MTMRC_PONAB4.726e-2227.35Myotubularin-related protein 12 OS=Pongo abelii OX... [more]
sp|Q80TA6|MTMRC_MOUSE5.434e-2226.80Myotubularin-related protein 12 OS=Mus musculus OX... [more]
sp|Q9C0I1|MTMRC_HUMAN1.037e-2127.17Myotubularin-related protein 12 OS=Homo sapiens OX... [more]
sp|Q5U581|MTRAA_XENLA7.654e-1634.78Myotubularin-related protein 10-A OS=Xenopus laevi... [more]
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BLAST of Myotubularin related protein 12 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G3HIQ62.230e-2028.98Myotubularin-related protein 12 OS=Cricetulus gris... [more]
H0XAV24.382e-2029.11Myotubularin related protein 12 OS=Otolemur garnet... [more]
A0A0N5A9U25.499e-2030.94Myotubularin phosphatase domain-containing protein... [more]
A0A2I2YTX31.868e-1927.39Myotubularin related protein 12 OS=Gorilla gorilla... [more]
A0A1U7QS492.111e-1928.46myotubularin-related protein 12 OS=Mesocricetus au... [more]
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BLAST of Myotubularin related protein 12 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtmr101.440e-1531.06myotubularin related protein 10 [Source:NCBI gene;... [more]
mtmr124.757e-1528.74myotubularin related protein 12 [Source:NCBI gene;... [more]
mtmr112.237e-1428.92myotubularin related protein 11 [Source:NCBI gene;... [more]
mtmr112.237e-1428.92myotubularin related protein 11 [Source:NCBI gene;... [more]
mtmr112.334e-1428.92myotubularin related protein 11 [Source:NCBI gene;... [more]
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BLAST of Myotubularin related protein 12 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sbf15.641e-1229.53SET binding factor 1 [Source:ZFIN;Acc:ZDB-GENE-040... [more]
mtm12.143e-1128.78myotubularin 1 [Source:ZFIN;Acc:ZDB-GENE-051113-12... [more]
mtmr91.886e-926.04myotubularin related protein 9 [Source:ZFIN;Acc:ZD... [more]
ENSPMAT00000010382.11.845e-829.75pep scaffold:Pmarinus_7.0:GL482471:369374:413667:1... [more]
ENSPMAT00000002170.12.882e-736.71pep scaffold:Pmarinus_7.0:GL484749:1247:6808:1 gen... [more]
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BLAST of Myotubularin related protein 12 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Myotubularin related protein 12 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO375651.035e-1127.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO337744.675e-1128.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO444805.712e-1126.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO347102.423e-932.80Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO487081.953e-826.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Myotubularin related protein 12 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtmr112.530e-1529.95myotubularin related protein 11 [Source:NCBI gene;... [more]
mtmr112.855e-1529.95myotubularin related protein 11 [Source:NCBI gene;... [more]
mtmr113.069e-1529.95myotubularin related protein 11 [Source:NCBI gene;... [more]
mtmr107.817e-1531.06myotubularin related protein 10 [Source:NCBI gene;... [more]
mtmr107.817e-1531.06myotubularin related protein 10 [Source:NCBI gene;... [more]
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BLAST of Myotubularin related protein 12 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000019399.10.000e+098.94SMESG000019399.1[more]
SMESG000072462.15.617e-1026.38SMESG000072462.1[more]
SMESG000007673.19.587e-1029.50SMESG000007673.1[more]
SMESG000032817.13.658e-930.00SMESG000032817.1[more]
SMESG000032817.13.771e-930.00SMESG000032817.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027446 ID=SMED30027446|Name=Myotubularin related protein 12|organism=Schmidtea mediterranea sexual|type=transcript|length=2098bp
ATTTGTTTGAAATATTAGACACCAAACGGGGAAATTTGAATTAGTGAAAA
TATATTAAGTTATCCTTTTAGAATTTTTTTATCGACTATGAATGAAAATT
CTCCAAATAAAGCTTTGGCCGTGTTATATGAACCTATAGAATTGCAATCA
CATTTTAACTACAAAAAGAAATCTTTTATTGATAAATTACGAATCTCTAA
TCCAAATAGCAAGGATTCAAATAGTGATACACGCTTTACTGAAGGAATTC
TCATTATAGATCTTTCGAATAAACAATTGCTTTTTCGACCATATGAATCC
ATTCCATCACCAGATTTAATTTATTATCAGGAAAACTTCCATAAAAAATT
GACTATACAGGTGAATAATATTAAAAATATTATGTTTTTGAACAAAAACA
ATGAATATGTTACTTTCAAAAGTTCATCATCGATTGTGAAATCATATCAT
TCTTTTATTATAACGTGCTATGACTTCAGAGTTTATAGCTACAACCGAAT
TAGTATTTATAATAAAAATGATGCAATTAAATTCTACCAAGAAATTTTTC
GATTAGTGTTTGAAACGGAAGATGATCGAATGAAATGTGACATGTGGATG
AAAATAGGTGATGAGGTGCTGCGAGATGTTTACTACAAAACTGTCAATAA
CTCCATTAGAGTTAGATTCCAATCTATCAAAAAATATTTAGTCGTTTCAC
CAATTGATTTGTCAGCTAATAATCTTAAAGATAATTTTGAGTTCGGTCCT
CAGGTGGTTTACTACTCAGATCACAATGATTCCTGTCTGATAGTGATTGA
CAAGTCGAGCGGCAAGAAGTGCTCAAATTCACTGAAACATATTTCCAAAA
CAATTCTTGGACCCAAAATCAAAGTTGTTTTATTTCATTTGAATTGTGAA
AATTCAGAAAATAAATCGGAATTTTATTGTCCTACAAATAAGGAGCTCAT
CGAATCATTTGAAAAGCTCTACATACTCTGCACTCCTAGAAATAAAGCCG
AATTTAAAAAGAGGGATAAAAAATGGCTGTCAAAGCAAGCAGACTGCGGA
TGGTTAAACCTGGTTAACCGCTGTTTGCAATCAACAAAGATCATTATGAA
ATCGATGTCAGAATCGTGCTCTTCGGTTTTTTTAATGGAACAAGGCTATC
CGACCTGGGGCTGGTTATTCGGCAGTTTAGTGCAAATCATTTGCCAGCCA
TTTGTCCGAACAAGAAATGGATTTCTCTCCATGATTGAAAAAAACTGGAT
CATGTCAAATGCGTTTTATAATTCCGACGGTCCAAAATATTCTTTGTTTC
TGCTGTTTCTCGATTGCGTTTACCAGCTCCTCCGTTCCTCTCCATTTCTT
TTCGAGTTCAATGAAGAAATGCTTATTTTTTTATACGATCTTTTTATTTT
AGCTCCATCGGGATTTATGAATTCATTAGATTACGATTTCAAAGGAATAG
ATTGGTCATTGTATTTTGTAGATCAAGTGCTAGAGTGCTTGGATAATTAT
TACTATTTGGAAGAGTCATTCGATAGTTGTTTGTTCGTTCCAAAGGTGGA
CGTGATGGACTTTGGTAGTTTCTGGTTCAAAATGTACGCCAGATGGATCC
CTTATGTTCAAATCGAAAGCGGTTCAATGTCTGTTAGGCATTTTTTTATG
GTTGTGAATTTGAATTTAGAGAATCTTGTTTATACAAATTATCCGTTCTC
ATTAAATTATGATAAAATTACAATGAATTCCGATTACAACAACATAGACG
ACACGAGGTCCATTAACACATTGGGCAGTGACGACTAGGGAAATCCGATC
ATGAGATTATTATCTTTCTTTGCTTTCTAATTTTTACACTTGATCAGATA
TATTTTCAATTTTAATTTGCTCAATTTTAAGGTTGTTCGATTATTTTTGT
CGGTATTTATTTCAGGTCTATTTATGGAGCGGACCAATTGTTGTCAAATC
GACTGTGTTTTTGTAATATTTATTTTTATGCATAATATTGCATTTGAATT
AGGGTTTTGTTTTAATTCACTCATTGGAATTCGTTTGTTGATAAATTTAA
TTGAAATCTTCGTATTATCATCAAGATTTATATTATTATTATTATTAT
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protein sequence of SMED30027446-orf-1

>SMED30027446-orf-1 ID=SMED30027446-orf-1|Name=SMED30027446-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=567bp
MNENSPNKALAVLYEPIELQSHFNYKKKSFIDKLRISNPNSKDSNSDTRF
TEGILIIDLSNKQLLFRPYESIPSPDLIYYQENFHKKLTIQVNNIKNIMF
LNKNNEYVTFKSSSSIVKSYHSFIITCYDFRVYSYNRISIYNKNDAIKFY
QEIFRLVFETEDDRMKCDMWMKIGDEVLRDVYYKTVNNSIRVRFQSIKKY
LVVSPIDLSANNLKDNFEFGPQVVYYSDHNDSCLIVIDKSSGKKCSNSLK
HISKTILGPKIKVVLFHLNCENSENKSEFYCPTNKELIESFEKLYILCTP
RNKAEFKKRDKKWLSKQADCGWLNLVNRCLQSTKIIMKSMSESCSSVFLM
EQGYPTWGWLFGSLVQIICQPFVRTRNGFLSMIEKNWIMSNAFYNSDGPK
YSLFLLFLDCVYQLLRSSPFLFEFNEEMLIFLYDLFILAPSGFMNSLDYD
FKGIDWSLYFVDQVLECLDNYYYLEESFDSCLFVPKVDVMDFGSFWFKMY
ARWIPYVQIESGSMSVRHFFMVVNLNLENLVYTNYPFSLNYDKITMNSDY
NNIDDTRSINTLGSDD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR030564Myotubularin_fam
IPR010569Myotubularin-like_Pase_dom
IPR029021Prot-tyrosine_phosphatase-like
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
Vocabulary: molecular function
TermDefinition
GO:0019208phosphatase regulator activity
Vocabulary: biological process
TermDefinition
GO:0050790regulation of catalytic activity
GO:1901998toxin transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR010569Myotubularin-like phosphatase domainPFAMPF06602Myotub-relatedcoord: 285..435
e-value: 2.9E-24
score: 85.7
IPR010569Myotubularin-like phosphatase domainPROSITEPS51339PPASE_MYOTUBULARINcoord: 85..434
score: 21.164
NoneNo IPR availablePANTHERPTHR10807:SF110FI17948P1coord: 90..507
NoneNo IPR availableCDDcd14537PTP-MTMR10-likecoord: 281..413
e-value: 1.15898E-27
score: 108.198
IPR030564Myotubularin familyPANTHERPTHR10807MYOTUBULARIN-RELATEDcoord: 90..507
IPR029021Protein-tyrosine phosphatase-likeSUPERFAMILYSSF52799(Phosphotyrosine protein) phosphatases IIcoord: 257..505