Protein arginine N-methyltransferase 7

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSW-----------LKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKWICQN-NKYHWRDHWLQAVFCV---RNLNENKNLQFQFSHDQFSIW--IEMSDGKNGGKIE--KPFCSCGLHLHIPRNRIYQMNSREYS-KQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIG-----IVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPGEII 1972
            F S+ N   G +EWL  D +YDY+ EI  S YADML+D +RN  YY  ++  + ++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  ++ KN  FSDKI +IN HS ++ VG   +M  +AN+LV+E+FDTELIGEG L ++++A ++L+ EN   +P +AT Y Q++ES  +   SW           L E   +P  P   ++C G  SV DIQ + ++   F  + D + +  I+FS+     S   C S  +       + V+  WW++ M  E     +  P W   +  +  WRDHW+Q V+ +     + +   L     HD + +W  ++ +  +   ++   +P C C  HL   R R  ++N ++ + + +  +  +LK   +   + +SD S  S+   + G+     +++ +        +       +  +          N D+ G     ++G+P+F  S+ PW N++FW+ V +   Q  G   ++ P   ++ A++V+F DL +I +P  D +GFD+   D++I    D  +    +   LWEY C + S+  +++ FD +Q +  L  +    + +       +  VLW  + LT    +   L           W P  KQAV+F +    P  ++
Sbjct:    4 FCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNG-FSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRM--WSWNKLFPIHVQTSLGEQVIVP--PVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSK--QVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTVLKPDSV--CLCVSDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLEDKINIIEKRPELLTNEDLQGRKVSLLLGEPFFTTSLLPWHNLYFWY-VRTAVDQHLGPGAMVMPQAASLHAVVVEFRDLWRIRSPCGDCEGFDVHIMDDMIKRALDFRESREAEPHPLWEYPCRSLSEPWQILTFDFQQPVP-LQPLCAEGTVELRRPGQSHAAVLWMEYHLTPECTLSTGLLEPADPEGGCCWNPHCKQAVYFFSPAPDPRALL 662          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSW-----------LKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKWICQN-NKYHWRDHWLQAVFCV---RNLNENKNLQFQFSHDQFSIW--IEMSDGKNGGKIE--KPFCSCGLHLHIPRNRIYQMNSREYS-KQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIG-----IVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPGEII 1972
            F S+ N   G +EWL  D +YDY+ EI  S YADML+D +RN  YY  ++  + ++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  ++ KN  FSDKI +IN HS ++ VG   +M  +AN+LV+E+FDTELIGEG L ++++A ++L+ EN   +P +AT Y Q++ES  +   SW           L E   +P  P   ++C G  SV DIQ + ++   F  + D + +  I+FS+     S   C S  +       + V+  WW++ M  E     +  P W   +  +  WRDHW+Q V+ +     + +   L     HD + +W  ++ +  +   ++   +P C C  HL   R R  ++N ++ + + +  +  +LK   +   + +SD S  S+   + G+     +++ +        +       +  +          N D+ G     ++G+P+F  S+ PW N++FW+ V +   Q  G   ++ P   ++ A++V+F DL +I +P  D +GFD+   D++I    D  +    +   LWEY C + S+  +++ FD +Q +  L  +    + +       +  VLW  + LT    +   L           W P  KQAV+F +    P  ++
Sbjct:    4 FCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNG-FSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRM--WSWNKLFPIHVQTSLGEQVIVP--PVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSK--QVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTVLKPDSV--CLCVSDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLEDKINIIEKRPELLTNEDLQGRKVSLLLGEPFFTTSLLPWHNLYFWY-VRTAVDQHLGPGAMVMPQAASLHAVVVEFRDLWRIRSPCGDCEGFDVHIMDDMIKRALDFRESREAEPHPLWEYPCRSLSEPWQILTFDFQQPVP-LQPLCAEGTVELRRPGQSHAAVLWMEYHLTPECTLSTGLLEPADPEGGCCWNPHCKQAVYFFSPAPDPRALL 662          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSW-----------LKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKWICQN-NKYHWRDHWLQAVFCVRN---LNENKNLQFQFSHDQFSIW--IEMSDGKNGGKIE--KPFCSCGLHLHIPRNRIYQMNSREYS-KQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIG-----IVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKF 1555
            F S+ N   G +EWL  D +YDY+ EI  S YADML+D +RN  YY  ++  + ++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  ++ KN  FSDKI +IN HS ++ VG   +M  +AN+LV+E+FDTELIGEG L ++++A ++L+ EN   +P +AT Y Q++ES  +   SW           L E   +P  P   ++C G  SV DIQ + ++   F  + D + +  I+FS+     S   C S  +       + V+  WW++ M  E     +  P W   +  +  WRDHW+Q V+ +     + +   L     HD + +W  ++ +  +   ++   +P C C  HL   R R  ++N ++ + + +  +  +LK   +   + +SD S  S+   + G+     +++ +        +       +  +          N D+ G     ++G+P+F  S+ PW N++FW+ V +   Q  G   ++ P   ++ A++V+F
Sbjct:    4 FCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNG-FSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRM--WSWNKLFPIHVQTSLGEQVIVP--PVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSK--QVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTVLKPDSV--CLCVSDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLEDKINIIEKRPELLTNEDLQGRKVSLLLGEPFFTTSLLPWHNLYFWY-VRTAVDQHLGPGAMVMPQAASLHAVVVEF 524          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSW-----------LKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKWICQN-NKYHWRDHWLQAVFCVRN---LNENKNLQFQFSHDQFSIW--IEMSDGKNGGKIE--KPFCSCGLHLHIPRNRIYQMNSREYS-KQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIG-----IVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPGEII 1972
            F S+ N   G +EWL  D +YDY+ EI  S YADML+D +R                                                   F PM + A  ++ KN  FSDKI +IN HS ++ VG   +M  +AN+LV+E+FDTELIGEG L ++++A ++L+ EN   +P +AT Y Q++ES  +   SW           L E   +P  P   ++C G  SV DIQ + ++   F  + D + +  I+FS+     S   C S  +       + V+  WW++ M  E     +  P W   +  +  WRDHW+Q V+ +     + +   L     HD + +W  ++ +  +   ++   +P C C  HL   R R  ++N ++ + + +  +  +LK   +   + +SD S  S+   + G+     +++ +        +       +  +          N D+ G     ++G+P+F  S+ PW N++FW+ V +   Q  G   ++ P   ++ A++V+F DL +I +P  D +GFD+   D++I    D  +    +   LWEY C + S+  +++ FD +Q +  L  +    + +       +  VLW  + LT    +   L           W P  KQAV+F +    P  ++
Sbjct:    4 FCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDR--------------------------------------------------VFKPMADAAVKIVEKNG-FSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRM--WSWNKLFPIHVQTSLGEQVIVP--PVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSK--QVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTVLKPDSV--CLCVSDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLEDKINIIEKRPELLTNEDLQGRKVSLLLGEPFFTTSLLPWHNLYFWY-VRTAVDQHLGPGAMVMPQAASLHAVVVEFRDLWRIRSPCGDCEGFDVHIMDDMIKRALDFRESREAEPHPLWEYPCRSLSEPWQILTFDFQQPVP-LQPLCAEGTVELRRPGQSHAAVLWMEYHLTPECTLSTGLLEPADPEGGCCWNPHCKQAVYFFSPAPDPRALL 612          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIES 598
            F S+ N   G +EWL  D +YDY+ EI  S YADML+D +RN  YY  ++  + ++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  ++ KN  FSDKI +IN HS ++ VG   +M  +AN+LV+E+FDTELIGEG L ++++A ++L+ EN   +P +AT Y Q++ES
Sbjct:    4 FCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNG-FSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVES 187          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKK--FVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNL-----PSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYS------YVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCV---RNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIE-KPFCSCGLHLHIPRNRIYQMNSR-EYSKQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVF--DMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHF-INNHKFPGEIILKLVFDVDNCNFNFKFGINE 2032
            F+ K N   G+ EW++ + +YD   E+  S + DM+ D +RN  +   LK  I + K +     VHVLDIG G+GLLS+MA + GADKVTA E F PM +CA+++   N+ +SDKI +I+  S D  V      +A+++V+E+FDTELIGEG L TF  A++ L      ++P     Y+  +ES        LK    IP L           C G ++VFD+Q S +  + F  + +PI     +F        +K+ F   +  E   +S       ++WW++ M    T  I   PKW  +NN Y WRDHW+QAV+ +   + +  N+  +   +HD+FS+W       N GK + + +C CGLH  + R  +Y +N   E  K  D V +L K  H+ T   + + S+  +        + TIID +           ++     N          + + DI  ++ +P+++ ++ PW+++ F + VE + K   G    + P    +KA+  KF+DL  I + V  + GFD+  FDEI        D I  D + LWEY    + D  E++ F  D R S       S  C     + +  N + +W  WE   G+ +   L SI        W    KQ V+F I   +    + L  +FD    + NF+FG +E
Sbjct:    2 FLEKINQKTGEREWVVAEEDYDMAQELARSRFGDMILDFDRNDKFLAGLKTTIAEKKHENTDGKVHVLDIGTGTGLLSLMAAREGADKVTALEVFKPMGDCARHI-TSNSPWSDKITVISERSTD--VSQIGGSRADIIVAEVFDTELIGEGALRTFKEALERLAKPGCRVVPSTGNVYIVPVESHL------LKMFNDIPRLNGEKDEEPLGRCSGTAAVFDVQLSEMKTHEFRELSEPIVAFKFDFEH-----EEKIIFDESFVREAVAHSSGTIDALLMWWDIDMDRNGTTFIDMGPKWKNKNN-YAWRDHWMQAVYYLPEKKKVEMNQTFEIVCNHDEFSLWF-----SNVGKDKSRSYCVCGLHSMLSRQTVYHVNEMFENQKFKDEVDKLSKGLHVAT---VGEGSFLGLLAAKTAKRV-TIIDGNE-RFRDIFFKYIHYYKLTNVEIIEKVTSLTDSPDI--VLAEPFYMSAMNPWNHLRFLYDVE-VLKMMHGDELRVEPHMGVLKAIPEKFEDLQNIASDVGTVNGFDLSFFDEISTKARTATDAIV-DEQSLWEYAGIVKGDAVEILRFPIDGRVS-------SQKCVVNIDNMSSSNAIPMWMEWEFG-GINLSTGLLSISSAGVP-EWNKGYKQGVYFPITALRNDKSLCLHALFDKSTGDINFQFGKSE 645          

Query:   95 LTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIE 595
            LT  +Y ++       + +ML D  R   Y +++       K K     V+D+G G+G+LSM A K GA KV A E F  M   ++ ++  NNL    +++I     D+       EK ++++SE     L  E +L+T   A    L  N ++ P KA  Y+  IE
Sbjct:   21 LTSKDYYFDSYAHFGIHEEMLKDEVRTTTYRNSIYHNSHLFKDKV----VMDVGSGTGILSMFAAKAGAKKVFAME-FSNMALTSRKIIADNNL-DHIVEVIQAKVEDVHELPGGIEKVDIIISEWMGYCLFYESMLNTVLVARDRWLAPNGMLFPDKARLYVCAIE 181          

Query:   95 LTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIE 595
            LT  +Y ++       + +ML D  R   Y +++       K K     V+D+G G+G+LSM A K GA KV A E F  M   ++ ++  NNL    +++I     D+       EK ++++SE     L  E +L+T   A    L  N ++ P KA  Y+  IE
Sbjct:   21 LTSKDYYFDSYAHFGIHEEMLKDEVRTTTYRNSIYHNSHLFKDKV----VMDVGSGTGILSMFAAKAGAKKVFAME-FSNMALTSRKIIADNNL-DHIVEVIQAKVEDVHELPGGIEKVDIIISEWMGYCLFYESMLNTVLVARDRWLAPNGMLFPDKARLYVCAIE 181          

Query:  152 MLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQI 589
            M+ND  RN  +  AL   I     K +   V DIG G+G+LS +A +   + VTA E    +   +K VL +N + S     +N H+ +        EKA+++VSE  D  + GE ++ TF  A      +  + IP +AT Y+++
Sbjct:  145 MINDVKRNEAFAKALNDTI-----KSRITVVFDIGSGTGILSAIAAR-KTNLVTALEENMCLTMISKEVLKRNGVESR----VNVHAKNSTY-FETCEKADIVVSETLDCCVFGEKIVETFLDAHVRFSHDRTIFIPHQATVYVRL 279          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK-----ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSD-----KLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKW--------ICQNNKYH-------WRDHWLQAVFCVRN----LNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQ-IDFVTQLLKV------------------SHIGTA-VVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRP-GVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSI-------DIVNNK-ITWKPFTKQAVHFINNHKFPGEIILKL----VFDVDNCNFNFKFG 2023
            F    N + G+  W    ++YDY+ E+  +G+ DML+D  RN  Y+ AL++ I  M+   + VHVLDIG G+G+LSMMAL  GAD VTACE+F PM  CA+ +L  N    DK+ LI   S ++ VG +M  KAN+LV+E+ DTELIGEG +  +++A   LLTE+ + IP +A  Y Q+ +S      + LK     + + + + P   K+C G +++ D+Q S L +  F  + DP+++   +F +  +         KL    P +AE  FY    WW++ +  +    +S  P W          +  K H       WRDHW+QA++ +      L   K+      HD++S+W +  +      + +  C+C LH+   R+RI Q+N    +K+ + ++ + ++                   S +G A V++ +   FS  L      I++I+ ++ +  +         E++   +             +  I  +PYF+ +I PWDN +F   +  I+ + P GV   ISP    I A+ V+F DLHKI  PV   +GFD++ FDE++   + E      +++ LWEY C A S+ +E++  D   +    + + G+   K      CNG+ LW  W+L E    DNS +SI        +V  + + W  F +Q VHF      P E I  L    VF        F FG
Sbjct:    4 FSHVMNPITGQNSWQERGDDYDYHLEVANAGFGDMLHDWERNQKYFAALRKTIAGMREAGREVHVLDIGTGTGILSMMALAAGADSVTACEAFLPMANCAEKILAANGA-GDKVRLIRKRSTEIQVGEDMPRKANLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVAQSPLAAQWNSLKTIANLDGEPLLHPPEQLKSCQGEAALHDVQLSQLPSSAFRPLTDPVEIFQFDFQRKQEREKQRSQLLKLQSKQPGAAELVFY----WWDIQLDDDGEILLSCAPYWAHPQLKELAAEKAKDHPLPNVVPWRDHWMQAIYYIPKPLQLLEAGKSFHLSCHHDEYSLWFDAREEAPTKSVRRHTCTCDLHMTYSRSRIGQLNQSPRNKRYLRYLEESIEAEKSNVLVLGNGCLLGLASSALGAASVLLHEPHRFSRRL------IESIVKHNQLKNVQFLDKVEELEDSRLAA-------------LTHIFAEPYFLNAILPWDNFYFGTLLTKIKDRLPEGVK--ISPCSARIYALPVEFLDLHKIRAPVGSCEGFDLRLFDEMVE-RSAEQAVSLVEAQPLWEYPCRALSEPQEVLSVDF-SNFGQEHSLKGSIELK--HPRICNGVALWVDWQLVE----DNSPRSIVSSGPSEPVVPGEFVKWDMFVRQGVHFPRR---PKEAITHLEWSTVFKPLLGELTFSFG 686          

Query:   95 LTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIE 595
            +T  +Y ++       + +ML D  R   Y +A+       + K     VLD+GCG+G+LSM A K GA +V A +  + + E A+ V++ NNL  D I ++     ++ +  N  E  ++++SE     L  E +L T  YA    L ++ ++ P + T Y+  IE
Sbjct:   50 MTSRDYYFDSYAHFGIHEEMLKDEVRTVTYRNAMYHNKHLFQGKT----VLDVGCGTGILSMFAAKAGAAQVIAVDCSN-IIEFARQVVIDNNL-QDVITVVKGKIEEIELP-NGIEGVDIIISEWMGYCLFYESMLDTVLYARDKWLKKDGMMFPDRGTLYITAIE 209          

Query:  149 DMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYL 583
            +ML+D  R   Y  +L Q    ++ K     VLD+GCG+G+LS+ A K GA +V   ++ D ++  A +++ KN +  + ++LI     D  +      K ++++SE     L+ E +L +  YA +N L  N +I+P + T  L
Sbjct:  178 EMLSDKVRTSTYRASLLQNEAVVRGKT----VLDVGCGTGILSIFASKAGAARVVGIDNSDIVY-TAMDIIRKNKV--ENVELIKGRLEDTDLP---ETKYDIIISEWMGYFLLYESMLDSIIYARENHLNPNGIILPSRCTLSL 312          

Query:  149 DMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYL 583
            +ML+D  R   Y  +L Q    ++ K     VLD+GCG+G+LS+ A K GA +V   ++ D ++  A +++ KN +  + ++LI     D  +      K ++++SE     L+ E +L +  YA +N L  N +I+P + T  L
Sbjct:  220 EMLSDKVRTSTYRASLLQNEAVVRGKT----VLDVGCGTGILSIFASKAGAARVVGIDNSDIVY-TAMDIIRKNKV--ENVELIKGRLEDTDLP---ETKYDIIISEWMGYFLLYESMLDSIIYARENHLNPNGIILPSRCTLSL 354          

Query:   71 VNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLIN--CHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYL 583
             N K+ +L   ++  +    R   + +ML D  R   + DA+ Q     + K     VLD+GCG+G+LS+ A + GA KV A E  D + + A+ + +++N   + + ++       +L  G+   EK +++VSE     L  E ++++  +A    LT    I+P     +L
Sbjct:    5 ANQKLPFLEGKDSDYFQSYSRLETHMNMLRDSVRMQAFRDAIVQDGGLFQDKI----VLDVGCGTGILSLFAAEAGASKVIAVECTD-IADIAEEI-IRDNQKENVVKVVKGLVEQVELPDGI---EKVDIIVSEWMGNALYMEAMINSVLFARDKWLTRGGRILPSTGNLWL 168          

Query:   44 RNFISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKE-----NKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKW-ICQNNKYHWRDHWLQAVF---CVRNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPF---CSCGLHLHIPRNRIYQMNSREYSKQ-IDFVTQLLKVSHIGTAVVISDFSYFSI-----------SLVNAGLS---IQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPG-----EIILKLVFDVDNCNFNFKFGINE 2032
            + F  + N   G ++W+     YDY+ EI  S YADML+D +RN  YY+ ++  +R++K++ +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  ++ +N  FSDKI +IN HS ++ VG   +M E+AN+LV+E+FDTELIGEG L ++++A  +L+      +P +AT Y Q++ESD L   + ++      ++ +P  P   + C G  SV DIQ S +    F  I     +  ++FS+   S +    +++ + ++    + V+  WW++ M  E     +  P W     + Y WRDHW+Q+V+      N++E + L    SHD +S+W  ++  K       PF   C+C  HL   R R  ++N  + ++  +  +  +LK   +   + +SD S   +           SL ++G++   I+ ++  +S+    + L     + +      +          I  ++G+PYF  S+ PW ++ FW+   ++  Q    +  I P   T+ A+ V+F DL +I  P    +GFD+ P DE+I  + D  +    +   LWEY C A +    ++ FD  Q +     IS   +        C+G+ LW  ++LT+ + +   L           W P  KQ V F  + K        ++   L F+  + +    F I E
Sbjct:    2 KTFCGRANPTTGALDWVEESEEYDYHQEIARSCYADMLHDKDRNEKYYEGIRAAVRRIKARGERPVVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAQAASCIVERNG-FSDKIKIINKHSTEVTVGPDGDMQERANILVTELFDTELIGEGALPSYEHAHMHLVQTGCEAVPHRATIYAQLVESDMLWKWAQMRPIDVDGHRLMP--PGAVQECAGAPSVCDIQLSQVPTDAFTAISPVCTMFSVDFSKPVSSAAQS--YTVRFKSQTGGRAQVVLSWWDIDMDPEGNIVCTMAPSWSYADPHAYPWRDHWMQSVYFLPAEENVSEGEELMLMVSHDDYSLWYSLTHSKQNDVRVAPFRPCCTCQAHLVWTRPRFGELNDEQRTESYVSALRSMLKPDSV--CLSVSDGSLLPVFAHLLGSKKVFSLESSGMAKQVIEQVLHTNSLKDGVQLLGIRAEQLSLADLDGN---------QISVLMGEPYFSTSLLPWHSLFFWYCRTAV-AQLLQPDATILPRAATLYAVAVEFQDLWRIRFPCGTCEGFDVSPMDEMIQRSLDFRESWEAEPHPLWEYPCRALTKPCPVMTFDFTQCVPE-QPISSDGAVPFTGRGRCHGVALWMEYQLTDDISVSMGLTKAVSQEGACEWNPHRKQGVFFFRSAKETSGDGREDLSYSLTFEPHSGDIKMDFSITE 682          

Query:   44 RNFISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKE-----NKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKW-ICQNNKYHWRDHWLQAVF---CVRNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPF---CSCGLHLHIPRNRIYQMNSREYSKQ-IDFVTQLLKVSHIGTAVVISDFSYFSI-----------SLVNAGLS---IQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPG-----EIILKLVFDVDNCNFNFKFGINE 2032
            + F  + N   G ++W+     YDY+ EI  S YADML+D +RN  YY+ ++  +R++K++ +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  ++ +N  FSDKI +IN HS ++ VG   +M E+AN+LV+E+FDTELIGEG L ++++A  +L+      +P +AT Y Q++ESD L   + ++      ++ +P  P   + C G  SV DIQ S +    F  I     +  ++FS+   S +    +++ + ++    + V+  WW++ M  E     +  P W     + Y WRDHW+Q+V+      N++E + L    SHD +S+W  ++  +       PF   C+C  HL   R R  ++N  + ++  +  +  +LK   +   + +SD S   +           SL ++G++   I+ ++  +S+    + L     + +      +          I  ++G+PYF  S+ PW ++ FW+   ++  Q    +  I P   T+ A+ V+F DL +I  P    +GFD+ P DE+I  + D  +    +   LWEY C A +    ++ FD  Q +     IS   +        C+G+ LW  ++LT+ + +   L           W P  KQ V F  + K        ++   L F+  + +    F I E
Sbjct:    2 KTFCGRANPTTGALDWVEESEEYDYHQEIARSCYADMLHDKDRNEKYYEGIRAAVRRVKARGERPVVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAQAASCIVERNG-FSDKIKIINKHSTEVTVGPDGDMQERANILVTELFDTELIGEGALPSYEHAHMHLVQTGCEAVPHRATIYAQLVESDMLWKWAQMRPIDVDGHRLMP--PGAVQECAGAPSVCDIQLSQVPTDAFTAISPVCTMFSVDFSKPVSSAAQS--YTVRFKSQTGGRAQVVLSWWDIDMDPEGNIVCTMAPSWSYADPHAYPWRDHWMQSVYFLPAEENVSEGEELMLMVSHDDYSLWYSLTHSEQNDVRVAPFRPCCTCQAHLVWTRPRFGELNDEQRTESYVSALRSILKPDSV--CLSVSDGSLLPVFAHLLGSKKVFSLESSGMAKQVIEQVLHTNSLKDGVQLLGIRAEQLSLADLDGN---------QISVLMGEPYFSTSLLPWHSLFFWYCRTAV-AQLLQPDATILPRAATLYAVAVEFQDLWRIRFPCGTCEGFDVSPMDEMIQRSLDFRESWEAEPHPLWEYPCRALTKPCPVMTFDFTQCVPE-QPISSDGAVPFTGRGRCHGVALWMEYQLTDDISVSMGLTKAVSQEGACEWNPHRKQGVFFFRSAKETSGDGREDLSYSLTFEPHSGDIKMDFSITE 682          

Query:   44 RNFISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKE-----NKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKW-ICQNNKYHWRDHWLQAVF---CVRNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPF---CSCGLHLHIPRNRIYQMNSREYSKQ-IDFVTQLLKVSHIGTAVVISDFSYFSI-----------SLVNAGLS---IQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPG-----EIILKLVFDVDNCNFNFKFGINE 2032
            + F  + N   G ++W+     YDY+ EI  S YADML+D +RN  YY+ ++  +R++K++ +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  ++ +N  FSDKI +IN HS ++ VG   +M E+AN+LV+E+FDTELIGEG L ++++A  +L+      +P +AT Y Q++ESD L   + ++      ++ +P  P   + C G  SV DIQ S +    F  I     +  ++FS+   S +    +++ + ++    + V+  WW++ M  E     +  P W     + Y WRDHW+Q+V+      N++E + L    SHD +S+W  ++  +       PF   C+C  HL   R R  ++N  + ++  +  +  +LK   +   + +SD S   +           SL ++G++   I+ ++  +S+    + L     + +      +          I  ++G+PYF  S+ PW ++ FW+   ++  Q    +  I P   T+ A+ V+F DL +I  P    +GFD+ P DE+I  + D  +    +   LWEY C A +    ++ FD  Q +     IS   +        C+G+ LW  ++LT+ + +   L           W P  KQ V F  + K        ++   L F+  + +    F I E
Sbjct:    2 KTFCGRANPTTGALDWVEESEEYDYHQEIARSCYADMLHDKDRNEKYYEGIRAAVRRVKARGERPVVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAQAASCIVERNG-FSDKIKIINKHSTEVTVGPDGDMQERANILVTELFDTELIGEGALPSYEHAHMHLVQTGCEAVPHRATIYAQLVESDMLWKWAQMRPIDVDGHRLMP--PGAVQECAGAPSVCDIQLSQVPTDAFTAISPVCTMFSVDFSKPVSSAAQS--YTVRFKSQTGGRAQVVLSWWDIDMDPEGNIVCTMAPSWSYADPHAYPWRDHWMQSVYFLPAEENVSEGEELMLMVSHDDYSLWYSLTHSEQNDVRVAPFRPCCTCQAHLVWTRPRFGELNDEQRTESYVSALRSILKPDSV--CLSVSDGSLLPVFAHLLGSKKVFSLESSGMAKQVIEQVLHTNSLKDGVQLLGIRAEQLSLADLDGN---------QISVLMGEPYFSTSLLPWHSLFFWYCRTAV-AQLLQPDATILPRAATLYAVAVEFQDLWRIRFPCGTCEGFDVSPMDEMIQRSLDFRESWEAEPHPLWEYPCRALTKPCPVMTFDFTQCVPE-QPISSDGAVPFTGRGRCHGVALWMEYQLTDDISVSMGLTKAVSQEGACEWNPHRKQGVFFFRSAKETSGDGREDLSYSLTFEPHSGDIKMDFSITE 682          

Query:  152 MLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENP-------------VIIPFKATFYLQIIESDFLDNHSWL 625
            MLNDH RN  Y  A+K+ +    S      VLDIG G+G+L M A   GA +V ACE    M+E A  VL  N + +D I +++  S D+ +  ++  + +++V+E  D  L GEG++ T  +A K+LL   P              +IP  AT +   ++   +  H  L
Sbjct:  159 MLNDHGRNHKYQLAIKKAVEGGCSS-----VLDIGTGTGILGMCAKMAGAAEVYACELSKTMYELACEVLSANGM-ADCIKILHRKSLDMEIPKDIPNRVSLVVTETVDAGLFGEGIIETLIHAWKHLLLPAPNPGELLSSPSQTGRVIPAGATVFGVAVQCPEIRRHHRL 323          

Query:  152 MLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENP-------------VIIPFKATFYLQIIESDFLDNHSWL 625
            MLNDH RN  Y  A+K+ +    S      VLDIG G+G+L M A   GA +V ACE    M+E A  VL  N + +D I +++  S D+ +  ++  + +++V+E  D  L GEG++ T  +A K+LL   P              +IP  AT +   ++   +  H  L
Sbjct:  159 MLNDHGRNHKYQLAIKKAVEGGCSS-----VLDIGTGTGILGMCAKMAGAAEVYACELSKTMYELACEVLSANGM-ADCIKILHRKSLDMEIPKDIPNRVSLVVTETVDAGLFGEGIIETLIHAWKHLLLPAPNPGELLSSPSQTGRVIPAGATVFGVAVQCPEIRRHHRL 323          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK------ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWI-CQNNKYHWRDHWLQAVFCVRN---LNENKNLQFQFSHDQFSIWIEMSDGKNGGKI----EKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHI-GTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCD-----IIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINN 1948
            F  + N   G M+W+  D +YDY+ EI  S YADML+D +RN  YY  +   ++++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  + +K N FSDKI +IN HS ++ VGL  +M  KAN+L++E+FDTELIGEG L ++++A +NL+ +    +P  AT Y Q++ES  L   SW K      E   I   P   ++C G  SV D+Q S L+   F  + + + +  +NFSQ   S            A       + WWE+ M  + +   +  P W+        WRDHW+Q V+ +     + + +      + D + +W  ++       I    E+P C CG H+   R R  ++N R  +K   ++  L KV+    T + +SD S   +   + G      +++ SI +   E +                  S    D     I  ++G+P+F  S+ PW N++FW++  ++ K     +  + P   ++  + V+F DL +I +P    +GFD+   DE+I  + +  +    +   LWEY C A S+  +++ F+  + L    EI+ + S   V +  C+G VLW  +ELT+ + +   L  +     +  W P  KQ V+F ++
Sbjct:   19 FCGRVNPTTGAMDWVEEDEHYDYHQEIARSSYADMLHDKDRNEKYYQGICAAVKRVKKRGQEAVVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMSDAAVRI-VKANGFSDKIKVINKHSTEVTVGLDGDMKSKANILITELFDTELIGEGALPSYEHAQRNLMQDTWEAVPHCATVYAQLVESHRL--WSWNKLFPLNLETGDIRPHPEL-ESCPGAPSVCDVQLSQLSPKDFKILSEVLCVFRVNFSQQVSSSPTSHPVHFKCLARGAAQVVLSWWEIDMDPDGSITCTMQPSWMYLAQQPVPWRDHWMQCVYFLPKESLVTQGEMWCLTANQDDYCVWYSLTKSSTQQNILMCRERPACHCGAHITWNRARFGELNDRNRTKL--YLEALKKVATPSSTCLFVSDGSLLPVLAHSLGARQIYTLESSSISQHLMEKLFQVNHLGEKIQVLQKSADSLTPADFQDMKISALIGEPFFTTSLLPWHNLYFWYSRTALSKNL-AKDCAVLPYSASLHVVAVEFKDLWRIRSPCGICEGFDVSIMDEMIKNSLNFRESHDAEPHPLWEYPCRALSEPTKVMTFNFTE-LVPTEEINSSGSLNLVRSGQCHGAVLWMVYELTKEISISTGLTGVSEDTGECQWYPHRKQGVYFFSS 665          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK------ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCVRN---LNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHI-GTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINN 1948
            F  + N   G M+W+  D +YDY+ EI  S YADML+D +RN  YY  +   ++++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  + +K N FSDKI +IN HS ++ VGL  +M  KAN+L++E+FDTELIGEG L ++++A +NL+ +    +P  AT Y Q++ES  L   SW K      E   I   P   ++C G  SV D+Q S L+   F  + + + +  +NFSQ   S            A       + WWE+ M  + +   +  P W+     Y WRDHW+Q V+ +     + + +      + D + +W  ++      K  +P C CG H+   R R  ++N R  +K   ++  L KV+    T + +SD S   +   + G                                            I  ++G+P+F  S+ PW N++FW++  ++ K     +  + P   ++  + V+F DL +I +P    +GFD+   DE+I  + +  +    +   LWEY C A S+  +++ F+  + L    EI+ + S   V +  C+G VLW  +ELT+ + +   L  +     +  W P  KQ V+F ++
Sbjct:    4 FCGRVNPTTGAMDWVEEDEHYDYHQEIARSSYADMLHDKDRNEKYYQGICAAVKRVKKRGQEAVVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMSDAAVRI-VKANGFSDKIKVINKHSTEVTVGLDGDMKSKANILITELFDTELIGEGALPSYEHAQRNLMQDTWEAVPHCATVYAQLVESHRL--WSWNKLFPLNLETGDIRPHPEL-ESCPGAPSVCDVQLSQLSPKDFKILSEVLCVFRVNFSQQVSSSPTSHPVHFKCLARGAAQVVLSWWEIDMDPDGSITCTMQPSWM-----YLWRDHWMQCVYFLPKESLVTQGEMWCLTANQDDYCVWYSLTKTSKNKKQTRPACHCGAHITWNRARFGELNDRNRTKL--YLEALKKVATPSSTCLFVSDGSLLPVLAHSLGAR-----------------------------------------QISALIGEPFFTTSLLPWHNLYFWYSRTALSKNL-AKDCAVLPYSASLHVVAVEFKDLWRIRSPCGICEGFDVSIMDEMIKNSLNFRESHDAEPHPLWEYPCRALSEPTKVMTFNFTE-LVPTEEINSSGSLNLVRSGQCHGAVLWMVYELTKEISISTGLTGVSEDTGECQWYPHRKQGVYFFSS 594          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK------ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWI-CQNNKYHWRDHWLQAVFCVRN---LNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHI-GTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINN 1948
            F  + N   G M+W+  D +YDY+ EI  S YADML+D +RN  YY  +   ++++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  + +K N FSDKI +IN HS ++ VGL  +M  KAN+L++E+FDTELIGEG L ++++A +NL+ +    +P  AT Y Q++ES  L   SW K      E   I   P   ++C G  SV D+Q S L+   F  + + + +  +NFSQ   S            A       + WWE+ M  + +   +  P W+        WRDHW+Q V+ +     + + +      + D + +W  ++  +     E+P C CG H+   R R  ++N R  +K   ++  L KV+    T + +SD S   +   + G                                            I  ++G+P+F  S+ PW N++FW++  ++ K     +  + P   ++  + V+F DL +I +P    +GFD+   DE+I  + +  +    +   LWEY C A S+  +++ F+  + L    EI+ + S   V +  C+G VLW  +ELT+ + +   L  +     +  W P  KQ V+F ++
Sbjct:   10 FCGRVNPTTGAMDWVEEDEHYDYHQEIARSSYADMLHDKDRNEKYYQGICAAVKRVKKRGQEAVVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMSDAAVRI-VKANGFSDKIKVINKHSTEVTVGLDGDMKSKANILITELFDTELIGEGALPSYEHAQRNLMQDTWEAVPHCATVYAQLVESHRL--WSWNKLFPLNLETGDIRPHPEL-ESCPGAPSVCDVQLSQLSPKDFKILSEVLCVFRVNFSQQVSSSPTSHPVHFKCLARGAAQVVLSWWEIDMDPDGSITCTMQPSWMYLAQQPVPWRDHWMQCVYFLPKESLVTQGEMWCLTANQDDYCVWYSLTKSR-----ERPACHCGAHITWNRARFGELNDRNRTKL--YLEALKKVATPSSTCLFVSDGSLLPVLAHSLGAR-----------------------------------------QISALIGEPFFTTSLLPWHNLYFWYSRTALSKNL-AKDCAVLPYSASLHVVAVEFKDLWRIRSPCGICEGFDVSIMDEMIKNSLNFRESHDAEPHPLWEYPCRALSEPTKVMTFNFTE-LVPTEEINSSGSLNLVRSGQCHGAVLWMVYELTKEISISTGLTGVSEDTGECQWYPHRKQGVYFFSS 601          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK------ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWI-CQNNKYHWRDHWLQAVFCVRN---LNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHI-GTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINN 1948
            F  + N   G M+W+  D +YDY+ EI  S YADML+D +RN  YY  +   ++++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  + +K N FSDKI +IN HS ++ VGL  +M  KAN+L++E+FDTELIGEG L ++++A +NL+ +    +P  AT Y Q++ES  L   SW K      E   I   P   ++C G  SV D+Q S L+   F  + + + +  +NFSQ   S            A       + WWE+ M  + +   +  P W+        WRDHW+Q V+ +     + + +      + D + +W  ++  +      +P C CG H+   R R  ++N R  +K   ++  L KV+    T + +SD S   +   + G                                            I  ++G+P+F  S+ PW N++FW++  ++ K     +  + P   ++  + V+F DL +I +P    +GFD+   DE+I  + +  +    +   LWEY C A S+  +++ F+  + L    EI+ + S   V +  C+G VLW  +ELT+ + +   L  +     +  W P  KQ V+F ++
Sbjct:    4 FCGRVNPTTGAMDWVEEDEHYDYHQEIARSSYADMLHDKDRNEKYYQGICAAVKRVKKRGQEAVVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMSDAAVRI-VKANGFSDKIKVINKHSTEVTVGLDGDMKSKANILITELFDTELIGEGALPSYEHAQRNLMQDTWEAVPHCATVYAQLVESHRL--WSWNKLFPLNLETGDIRPHPEL-ESCPGAPSVCDVQLSQLSPKDFKILSEVLCVFRVNFSQQVSSSPTSHPVHFKCLARGAAQVVLSWWEIDMDPDGSITCTMQPSWMYLAQQPVPWRDHWMQCVYFLPKESLVTQGEMWCLTANQDDYCVWYSLTKSRYNPSF-RPACHCGAHITWNRARFGELNDRNRTKL--YLEALKKVATPSSTCLFVSDGSLLPVLAHSLGAR-----------------------------------------QISALIGEPFFTTSLLPWHNLYFWYSRTALSKNL-AKDCAVLPYSASLHVVAVEFKDLWRIRSPCGICEGFDVSIMDEMIKNSLNFRESHDAEPHPLWEYPCRALSEPTKVMTFNFTE-LVPTEEINSSGSLNLVRSGQCHGAVLWMVYELTKEISISTGLTGVSEDTGECQWYPHRKQGVYFFSS 599          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK------ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCVRN---LNENKNLQFQFSHDQFSIWIEMSDGKNGGK--------IEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHI-GTAVVISDFSYFSISLVNAG-------LSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINN 1948
            F  + N   G M+W+  D +YDY+ EI  S YADML+D +RN  YY  +   ++++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM + A  + +K N FSDKI +IN HS ++ VGL  +M  KAN+L++E+FDTELIGEG L ++++A +NL+ +    +P  AT Y Q++ES  L   SW K      E   I   P   ++C G  SV D+Q S L+   F  + + + +  +NFSQ   S            A       + WWE+ M  + +   +  P W+    +  WRDHW+Q V+ +     + + +      + D + +W  ++  +             E+P C CG H+   R R  ++N R  +K   ++  L KV+    T + +SD S   +   + G       L    ++    +++L +             S  SL      +  I  ++G+P+F  S+ PW N++FW++  ++ K     +  + P   ++  + V+F DL +I +P    +GFD+   DE+I  + +  +    +   LWEY C A S+  +++ F+  + L    EI+ + S   V +  C+G VLW  +ELT+ + +   L  +     +  W P  KQ V+F ++
Sbjct:    4 FCGRVNPTTGAMDWVEEDEHYDYHQEIARSSYADMLHDKDRNEKYYQGICAAVKRVKKRGQEAVVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMSDAAVRI-VKANGFSDKIKVINKHSTEVTVGLDGDMKSKANILITELFDTELIGEGALPSYEHAQRNLMQDTWEAVPHCATVYAQLVESHRL--WSWNKLFPLNLETGDIRPHPEL-ESCPGAPSVCDVQLSQLSPKDFKILSEVLCVFRVNFSQQVSSSPTSHPVHFKCLARGAAQVVLSWWEIDMDPDGSITCTMQPSWMYLAQQ-PWRDHWMQCVYFLPKESLVTQGEMWCLTANQDDYCVWYSLTKSRYNPSFESSADWYFERPACHCGAHITWNRARFGELNDRNRTKL--YLEALKKVATPSSTCLFVSDGSLLPVLAHSLGARQLDQILPYILLLCYLCLIQLFQVNHLGEKIQVLQKSADSLTPADFQDMKISALIGEPFFTTSLLPWHNLYFWYSRTALSKNL-AKDCAVLPYSASLHVVAVEFKDLWRIRSPCGICEGFDVSIMDEMIKNSLNFRESHDAEPHPLWEYPCRALSEPTKVMTFNFTE-LVPTEEINSSGSLNLVRSGQCHGAVLWMVYELTKEISISTGLTGVSEDTGECQWYPHRKQGVYFFSS 654          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSW-----------LKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKWICQN-NKYHWRDHWLQAVFCVRN---LNENKNLQFQFSHDQFSIWIEMS----DGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIGTAV--VISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIG-----IVGDPYFIYSIFPWDNIHFWFAVESIRKQ-RPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINN 1948
            F  + N   G +EWL  D +YDY+ EI  S YADML+D +RN  YY  ++  + ++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM E A  ++ +N  FSDKI +IN HS ++ VG   ++  +AN+L++E+FDTELIGEG L ++++A K+L+ E+   +P +AT Y Q++ES  +   SW           L E   +P  PS  + C G  SV DIQ + ++   F  + D + +  ++FS+     S   C S  +       + V+  WW++ M  E     +  P W   +  +  WRDHW+Q V+ +     + +         HD + +W  +     D  +     +P C C  HL   R R  ++N ++   + D   Q L+   +  +V   +SD S  S+   + G      +++        + +       +  S  +         D+ G     ++G+P+F  S+ PW N++FW+   S+ +   PG   ++ P   ++ A++V+F DL +I +P  D +GFD+   D++I  + D  +    +   LWEY C + S  +E++ FD +Q +      S   + +       +G VLW  ++LT    +   L +         W P  KQAV+F++ 
Sbjct:    4 FCGRANPTTGSLEWLEEDEHYDYHQEIARSSYADMLHDKDRNIKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAEAAVKIVERNG-FSDKIKVINKHSTEVTVGPDGDLPCRANILITELFDTELIGEGALPSYEHAHKHLVQEDCEAVPHRATVYAQLVESRRM--WSWNKLFPVRVRTSLGEQVIVP--PSELERCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSVDFSK--QVSSSAACHSRQFVPLASGQAQVVLSWWDIEMDPEGKIKCTMAPFWAQTDPQELQWRDHWMQCVYFLPQEEPVVQGSPRCLVAHHDDYCVWYSLQRTSPDENDSAYQVRPVCDCQAHLLWNRPRFGEINDQD---RTDHYAQALRTVLLPGSVCLCVSDGSLLSMLAHHLGAEQVFTVESSVASYRLMKRIFKVNHLEDKISVINKRPELLTAADLEGKKVSLLLGEPFFTTSLLPWHNLYFWYVRTSVDQHLAPGA--VVMPQAASLHAVIVEFRDLWRIRSPCGDCEGFDVHIMDDMIKHSLDFRESREAEPHPLWEYPCRSLSKPQEILTFDFQQPIPQQPMQSKG-TMELTRPGKSHGAVLWMEYQLTPDSTISTGLINPAEDKGDCCWNPHCKQAVYFLST 654          

Query:   92 LLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSW-----------LKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKW 916
            L  D +YDY+ EI  S YADML+D +RN  YY  ++  + ++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM E A  ++ +N  FSDKI +IN HS ++ VG   ++  +AN+L++E+FDTELIGEG L ++++A K+L+ E+   +P +AT Y Q++ES  +   SW           L E   +P  PS  + C G  SV DIQ + ++   F  + D + +  ++FS+     S   C S  +       + V+  WW++ M  E     +  P W
Sbjct:    2 LEEDEHYDYHQEIARSSYADMLHDKDRNIKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAEAAVKIVERNG-FSDKIKVINKHSTEVTVGPDGDLPCRANILITELFDTELIGEGALPSYEHAHKHLVQEDCEAVPHRATVYAQLVESRRM--WSWNKLFPVRVRTSLGEQVIVP--PSELERCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSVDFSK--QVSSSAACHSRQFVPLASGQAQVVLSWWDIEMDPEGKIKCTMAPFW 284          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLL 538
            F  + N   G +EWL  D +YDY+ EI  S YADML+D +RN  YY  ++  + ++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM E A  ++ +N  FSDKI +IN HS ++ VG   ++  +AN+L++E+FDTELIGEG L ++++A K+L+
Sbjct:    4 FCGRANPTTGSLEWLEEDEHYDYHQEIARSSYADMLHDKDRNIKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAEAAVKIVERNG-FSDKIKVINKHSTEVTVGPDGDLPCRANILITELFDTELIGEGALPSYEHAHKHLV 167          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNL 376
            F  + N   G +EWL  D +YDY+ EI  S YADML+D +RN  YY  ++  + ++K + +   VLDIG G+GLLSMMA+  GAD   A E F PM E A  ++ +N  
Sbjct:    4 FCGRANPTTGSLEWLEEDEHYDYHQEIARSSYADMLHDKDRNIKYYQGIRAAVSRVKDRGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMAEAAVKIVERNGF 112          

Query:  152 MLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPV------------IIPFKATFYLQIIE-SDFLDNHSWLKENKYIPNLPSFYK-TCHGYSSVFDIQASLLTNYRFNFIGDP---------IKLKVINFSQIHD--SFSDKLCFS--IPYSAENPFYSYVIWWELTMTSENTNCISTVP-KWICQNNKYHWRDHWLQAVFCVRNLNE 991
            MLND  RN  Y  A+++ +  + S+     VLDIG G+G+LSM A K GA  V ACE    M+E A +V+  N +  + I L++  S D+ +  ++ E+ +++V+E  D  + GEG++ +  +A ++LL +               +IP  A  +   +E ++   +H    ++    +LP+  K     Y+SV D + ++         G P          ++  ++F+ + +  S + K   S  +P   E    + ++W+ L +  E +  +ST P +  C          W QAV+ V+ L +
Sbjct:  156 MLNDTRRNMVYNAAIQKAV-CLGSRT----VLDIGTGTGILSMFAKKAGAQSVYACELSKTMYELACDVVAANKM-ENGIKLLHMKSLDIEIPKHIPERVSLVVTETVDAGVFGEGIVESLIHAWEHLLLQPKTKEENGNCGKYGKVIPAGAVIFGMAVECAEIRRHHRVGAKDIAGIHLPTNVKFQSPAYTSV-DTEETVEPYTTEKMSGIPGGYLPLTECFQIMKVDFNNLQELKSLATKKPHSLNVPAIKEGVLDAIMVWFVLQLDDEYS--LSTSPSEETC----------WEQAVYPVQALED 444          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK-----ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSD-----KLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQN---------------NKYHWRDHWLQAVFCVRN----LNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIG---IVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSI-------DIVNNK-ITWKPFTKQAVHFINNHKFP-GEIILKLVFDVDNCNFNFKFG 2023
            F    N + G+  W    ++YDY+ E+  +G+ DML+D  RN  Y+ ALK+ I  M+   + VHVLDIG G+G+LSMMA++ GAD VTACE+F PM  CA+ +L  N    DK+ LI   S ++ VG +M  KAN+LV+E+ DTELIGEG +  +++A   LLTE+ + IP +A  Y Q+ +S      + LK     + + + + P   K+C G +++ D+Q S L +  F  + DP+++   +F +  +         KL    P +AE  FY    WW++ +       +S  P W                   N   WRDHW+QA++ +      +   K+      HD++S+W +  +      + +  C+C LH+   R+RI Q+N    +K+  ++  L +      + V+   +   + L ++ L   +++ ++      + L  +   N         +     +  +     I  +PYF+ +I PWDN +F   +  I+ + P  N  ISP    I A+ V+F DLHKI  PV   +GFD++ FDE++   + E      +++ LWEY C A S+ +E++  +   +    + + G+   K   +  CNG+ LW  W+L E    DNS +SI        +V  + + W  F +Q VHF    K P   +     F  +    NF FG
Sbjct:    4 FSQAINPITGQNSWQERGDDYDYHLEVANAGFGDMLHDWERNQKYFAALKKTIAGMREAGREVHVLDIGTGTGILSMMAVEAGADSVTACEAFLPMANCAERILAANGA-GDKVRLIRKRSTEIQVGEDMPRKANLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVAQSPLAAQWNSLKTIANLDGEPLLHPPEQLKSCQGEAALHDVQLSQLPSSAFRPLTDPVEIFQFDFQRKQEREKQRAQLLKLQSKQPGAAELVFY----WWDIQLDDGGEILLSCAPYWAHPQLKELAAEKGNDHPLPNVVPWRDHWMQAIYYIPKPLQLVEAGKSFHLSCHHDEYSLWFDAREEAPTKSVRRHTCTCDLHMTYSRSRIGQINQSPRNKR--YLRYLEESIEAEKSNVLVLGNGCLLGLASSALGAASVLLHEPHRFSRRLLESIVKHNQLKNVQFLDKVEELEDSQLAALTHIFAEPYFLNAILPWDNFYFGTLLTKIKDRLPQ-NVKISPCSARIYALPVEFLDLHKIRAPVGSCEGFDLRLFDEMVE-RSAEQAVSLVEAQPLWEYPCRALSEPQEVLNVEF-SNFSQEHSLKGSIELK--HSGTCNGVALWVDWQLVE----DNSPRSIVSSGPSEPVVPGEFVKWDMFVRQGVHFPRRPKEPITHLEWSTAFKPELGELNFTFG 686          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK-----ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSD-----KLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKW--------ICQNNKYH-------WRDHWLQAVFCVRN----LNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQ-IDFVTQLLKV------------------SHIGTA-VVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRP-GVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSI-------DIVNNK-ITWKPFTKQAVHFINNHKFPGEIILKL----VFDVDNCNFNFKFG 2023
            F    N + G+  W    ++YDY+ E+  +G+ DML+D  RN  Y+ AL++ I  M+   + VHVLDIG G+G+LSMMAL  GAD VTACE+F PM  CA+ +L  N    DK+ LI   S ++ VG +M  KAN+LV+E+ DTELIGEG +  +++A   LLTE+ + IP +A  Y Q+ +S      + LK     + + + + P   K+C G +++ D+Q S L +  F  + DP+++   +F +  +         KL    P +AE  FY    WW++ +  +    +S  P W          +  K H       WRDHW+QA++ +      L   K+      HD++S+W +  +      + +  C+C LH+   R+RI Q+N    +K+ + ++ + ++                   S +G A V++ +   FS  L      I++I+ ++ +  +         E++   +             +  I  +PYF+ +I PWDN +F   +  I+ + P GV   ISP    I A+ V+F DLHKI  PV   +GFD++ FDE++   + E      +++ LWEY C A S+ +E++  D   +    + + G+   K      CNG+ LW  W+L E    DNS +SI        +V  + + W  F +Q VHF      P E I  L    VF        F FG
Sbjct:    4 FSHVMNPITGQNSWQERGDDYDYHLEVANAGFGDMLHDWERNQKYFAALRKTIAGMREAGREVHVLDIGTGTGILSMMALAAGADSVTACEAFLPMANCAEKILAANGA-GDKVRLIRKRSTEIQVGEDMPRKANLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVAQSPLAAQWNSLKTIANLDGEPLLHPPEQLKSCQGEAALHDVQLSQLPSSAFRPLTDPVEIFQFDFQRKQEREKQRSQLLKLQSKQPGAAELVFY----WWDIQLDDDGEILLSCAPYWAHPQLKELAAEKAKDHPLPNVVPWRDHWMQAIYYIPKPLQLLEAGKSFHLSCHHDEYSLWFDAREEAPTKSVRRHTCTCDLHMTYSRSRIGQLNQSPRNKRYLRYLEESIEAEKSNVLVLGNGCLLGLASSALGAASVLLHEPHRFSRRL------IESIVKHNQLKNVQFLDKVEELEDSRLAA-------------LTHIFAEPYFLNAILPWDNFYFGTLLTKIKDRLPEGVK--ISPCSARIYALPVEFLDLHKIRAPVGSCEGFDLRLFDEMVE-RSAEQAVSLVEAQPLWEYPCRALSEPQEVLSVDF-SNFGQEHSLKGSIELK--HPRICNGVALWVDWQLVE----DNSPRSIVSSGPSEPVVPGEFVKWDMFVRQGVHFPRR---PKEAITHLEWSTVFKPLLGELTFSFG 686          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK-----ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSD-----KLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKW--------ICQNNKYH-------WRDHWLQAVFCVRN----LNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIG---IVGDPYFIYSIFPWDNIHFWFAVESIRKQRP-GVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSI-------DIVNNK-ITWKPFTKQAVHFINNHKFPGEIILKLVFDVD----NCNFNFKFG 2023
            F+   N + G+  W    ++YDY+ E+  +G+ DML+D  RN  Y+ AL++ I  M+   + VHVLDIG G+G+LSMMAL  GAD VTACE+F PM  CA+ +L  N    DK+ LI   S ++ VG +M  KAN+LV+E+ DTELIGEG +  +++A   LLTE+ + IP +A  Y Q+ +S      + LK     + + + + P   K+C G +++ D+Q S L    F  + DP+++   +F +  +         KL    P +AE  FY    WW++ +       +S  P W          +  K H       WRDHW+QA++ +      L   K+      HD++S+W +  +      + +  C+C LH+   R RI Q+N    +K+  ++  L +      + V+   +   + L ++ L   +++ ++      + L  +   N         +     +  +     I  +PYF+ +I PWDN +F   +  I+ + P GV   ISP    I A+ V+F DLHKI  PV   +GFD++ FDE++   + E      +++ LWEY C A S+ +E++  D   +    + + G+   K      CNG+ LW  W+L E    DNS +SI        +V  + + W  F +Q VHF      P + +  L +  D        NF FG
Sbjct:    4 FLQVMNPITGQNSWQERGDDYDYHLEVANAGFGDMLHDWERNQKYFGALRKTIAGMREAGREVHVLDIGTGTGILSMMALAAGADSVTACEAFLPMANCAEKILAANGA-GDKVRLIRKRSTEIQVGEDMPRKANLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVAQSPLAAQWNSLKTIANLDGEPLLHPPEQLKSCQGEAALHDVQLSQLPISAFRPLTDPVEIFQFDFQRKQEREKQRAQLLKLQSKQPGAAELVFY----WWDIQLDDGGEILLSCAPYWAHPQLKELAAEKAKDHPLPNVVPWRDHWMQAIYYIPKPLQLLEAGKSFHLSCHHDEYSLWFDAREEAPTKSVRRHTCTCDLHMTYSRGRIGQLNQSPRNKR--YLRYLEESIEAEKSNVLVLGNGCLLGLASSALGAASVLLHEPHRFSRRLLESIVKHNQLKNVQFLDKVEELEDSQLAALTHIFAEPYFLNAILPWDNFYFGSLLTKIKDRLPEGVK--ISPCSARIYALPVEFLDLHKIRAPVGSCEGFDLRLFDEMVE-RSAEQAVSLVEAQPLWEYPCRALSEPQEVLSVDF-SNFGQEHSLKGSIELKHTGI--CNGVALWVYWQLVE----DNSPRSIVSSGPSEPVVPGEFVKWDMFVRQGVHFPRK---PKDAVTHLEWSTDFKPLLGELNFSFG 686          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK-----ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSD-----KLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKW---------------ICQNNKYHWRDHWLQAVFCVRN----LNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIV---GDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNK--------ITWKPFTKQAVHF 1939
            F    N + G+  W   +++YDY+ E+  +G+ DML+D  RN  Y+ AL++ I +M++  K VHVLDIG G+G+LSMMAL+ GAD VTACE+F PM  CA+ +L  N   +DK+ LI   S D+ +G +M  KAN+LV+E+ DTELIGEG +  +++A   LLTE+ + IP +A  Y Q+ +S      + LK     + + +   P+  K C G + + D+Q S L ++ F  + DP+++   +F +            K+  + P SAE  FY    WW++ +       +S  P W               +   N   WRDHW+QA++ +      L   K+      HD++S+W +  +      + +  C+C LH+   R+RI QMN    +K+  ++  L +      + V+   +   + L ++ L   ++  ++      + L  +   N         +     +  + G+     +PYF+ +I PWDN +F   +  I+ + P  +  ISP    I A+ V+F DLHKI  PV   +GFD++ FDE++   + E      +++ LWEY C A S+ +E++  D  +  E  + + G    K      CNG+ LW  W+L      D+S +SI              + W  F +Q VHF
Sbjct:    4 FSQVLNPITGENSWQEREDDYDYHQEVANAGFGDMLHDWERNQKYFAALRKTIAEMRTAGKEVHVLDIGTGTGILSMMALEAGADSVTACEAFLPMANCAEKILAANGA-ADKVRLIRKRSTDIQIGEDMPRKANLLVAELLDTELIGEGAIGIYNHAHDELLTEDALCIPARARCYAQVAQSPLAAQWNSLKSLANLDGEPLLQPPAQLKGCKGEAGLHDVQLSQLPSHTFRPLTDPVEIFQFDFQRKKQREKKRDQLLKVQSNQPGSAELVFY----WWDIQLDDGGEILLSCAPYWAHPEIHELSGKKGKDLPLPNVVPWRDHWMQAIYYIPKPLQLLEAGKSFHLSCHHDEYSLWFDAREEAPAKSVSRHTCTCDLHMTYSRSRIGQMNQSTRNKR--YLRYLEENIEAEKSKVLVLGNGCLLGLASSALGATSVQLHEPHRFSRRLLESIVQHNQLKNVEFVDKVEEVEDSQLAGLTHVFAEPYFLNAILPWDNFYFGTLLAKIKDKLPE-DVKISPCSARIYALPVEFLDLHKIRAPVVSCEGFDLRLFDEMVE-RSAEQAVTLVEAQPLWEYPCRALSEPQEILNVDFNKFSEE-HHLKGTIDLKH--PGTCNGVALWVDWQLIN----DSSPRSIVSTGPSEAVTPGEFVKWDMFVRQGVHF 657          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK-----ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSD-----KLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKW--------ICQNNKYH-------WRDHWLQAVFCVRN----LNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIG---IVGDPYFIYSIFPWDNIHFWFAVESIRKQRP-GVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSI-------DIVNNK-ITWKPFTKQAVHFINNHKFPGEIILKLVFDVD----NCNFNFKFG 2023
            F    N + G+  W    ++YDY+ E+  +G+ DML+D  RN  Y+ AL++ I  M+   + VHVLDIG G+G+LSMMAL  GAD VTACE+F PM  CA+ +L  N    DK+ LI   S ++ VG +M  KAN+LV+E+ DTELIGEG +  +++A   LLTE+ + IP +A  Y Q+ +S      + LK     + + + + P   K+C G +++ D+Q S L +  F  + DP+++   +F +  +         KL    P +AE  FY    WW++ +       +S  P W          +  K H       WRDHW+QA++ +      L   K+      HD++S+W +  +      + +  C+C LH+   R+RI Q+N    +K+  ++  L +      + V+   +   + L ++ L   +++ ++      + L  +   N         +     +  +     I  +PYF+ +I PWDN +F   +  I+ + P GV  L  P    I A+ V+F DLHKI  PV   +GFD++ FDE++   + E      +++ LWEY C A S+ +E++  D   +    + + G+   K      CNG+ LW  W+L E    DNS +SI        +V  + + W  F +Q VHF      P + +  L +  D        NF FG
Sbjct:   19 FSQVMNPITGQNSWQERGDDYDYHLEVANAGFGDMLHDWERNQKYFAALRKTIAGMREAGREVHVLDIGTGTGILSMMALAAGADSVTACEAFLPMANCAEKILAANGA-GDKVRLIRKRSTEIQVGEDMPRKANLLVAELLDTELIGEGAIGIYNHAHAELLTEDALCIPARARCYAQVAQSPLAAQWNSLKTIANLDGEPLLHPPEQLKSCQGEAALHDVQLSQLPSSAFRPLTDPVEIFQFDFQRKQEREKQRAQLLKLQSKQPGAAELVFY----WWDIQLDDGGEILLSCAPYWAHPQLKELAAEKAKDHPLPNVVPWRDHWMQAIYYIPKPLQLLEAGKSFHLSCHHDEYSLWFDAREEAPTKSVRRHTCTCDLHMTYSRSRIGQLNQSPRNKR--YLRYLEESIEAEKSNVLVLGNGCLLGLASSALGAASVLLHEPHRFSRRLLESIVKHNQLKNVHFLDKVEELEDSQLAALTHIFAEPYFLNAILPWDNFYFGTLLTKIKDKLPEGVKIL--PCSARIYALPVEFLDLHKIRAPVGSCEGFDLRLFDEMVE-RSAEQAVSLVEAQPLWEYPCRALSEPQEVLSVDF-SNFGQEHSLKGSIELKHTGI--CNGVALWVDWKLVE----DNSPRSIVSSGPSEPVVPGEFVKWDMFVRQGVHFPRK---PKDAVTHLEWSTDFKPLLGELNFSFG 701          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDN----HSWLKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSD-KLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKW------ICQNNKYH---------WRDHWLQAVF---CVRNLNENKNLQFQFSHDQFSIWIEMSDGK--NGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQL-LKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINN 1948
            FI   N + G + W   D NYDY+ E+  S +ADML+DH RN  YY  +K  I +     +  +VLDIG G+GLL+MMA K GAD VTACE+F PM +CA  ++ +N  F + I LI+  S  +I+G   +M +KAN+LV+E+FDTELIGEG LSTF +A +NLL EN ++IP  AT ++Q++ES  +      H     +KY+ N P   K+C G ++V DIQ +   +  F  +  P  +   + S       D K C  +  +A    ++  +WW+L M   N   +S  P W      I QN             WRDHW+QA++      ++  N  +     HD++S+W ++ +         E+P CSC +H+   R RI Q+N  +Y++   ++  L  K++     + +SD     ++ V  G     I++ + + +   E+     E +         +       I  I G+PYFI SI PW+N++FW+      +  P +  +  P+  TI  ++V+F DL+KI  P+   +GFD+  FD++I  ++D++D    +++ LWEY   A S    +  FD+ Q +    +++ +     + +  CNG+ LW  W+L   + + +          +I+W PFT+Q VH   +
Sbjct:    4 FIQCLNALTGIINWEEKDENYDYHQEVARSAFADMLHDHERNQKYYLGIKAAIEKKHKNGEEANVLDIGTGTGLLAMMAAKCGADSVTACEAFTPMAKCAIKIIQENG-FENNIKLIHKRSTKMIIGKDGDMIKKANILVTEVFDTELIGEGALSTFRHAHENLLEENSIVIPHTATIWIQVVESPTICTWNTVHPIQNRSKYLLNTPHSVKSCSGAAAVHDIQLTQFPHNAFKPLLPPQPIFRFDLSGKSTLLYDEKRCLHVKPTASGTAHAIFMWWDLIMDVNNEILLSCAPVWEHSDTKILQNKGLSLQEIADVIPWRDHWMQAIYYLPVATSVITNNEVSLIGYHDEYSLWFQLINESINEAPDCERPVCSCNVHIAYCRTRIGQLN--DYARNKKYIKALEKKITPDTVCLCLSDGCLLGLAAVQLGAKKIFILETNFLSRKCIEMFVKTNELSEKIEIVESVDELPPQSAINFIFGEPYFITSIVPWENLYFWYLAS---RYSPQIQRI--PIAATIMGVIVEFKDLYKIRAPLGVCEGFDLSIFDKLIQASSDKSDS-SIEAQPLWEYPTKALSLPFVIKTFDLTQDVNEHEDVNTSECVPVLTSGMCNGVALWIDWQLNSEITVSSGPTVKVQPGERISWDPFTRQGVHLFKD 655          

Query:   11 ILYERIMMLKYRNFISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLN--MNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK-----ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKWI---------CQNNKYHWRDHWLQAVFCVRN---LNENKNLQFQFSHDQFSIWIEMSDG---KNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFV--------TQLLKVSH-IGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWEL--TEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPGEIILKLVFDVDNCNFNFK 2017
            ++++R+ +L  R      N + G+ +W + +  YDY+ EI  S YADML+D  RN  YY+ALK  I +M  + K  +VLDIG G+GLLSMMA+K GAD V ACE F PM +CAK ++  N  FSD I ++N  S +L VG N  + E+AN+LV+E+FDTELIGEG L TF +A K LL  +  +IP  A  Y Q++ES    N + LK     + + + ++P+  +TCHG ++V DIQ S   +  FN +  P  +   +FS    +F+ K    +   +++   + V+  WW+L M  +N   +S  P W           ++ +  WRDHW+QAV+ + +   + ++K L F   HD++S+W  +       N   +  P C CG+H+   R RI Q+N    +K+   V        +Q+L +SH     +V S      +  +   + I+ I+ +         +      N + Y        S    +I  + G+P+F+ +I PWD++HF + +E  +   P  N +I P K+ IK + V F DL+KI  P+ + +GF+MKPFDE+I  ++  +D    +++ LWEY   A S+V  +   ++++  E  + I    +       +CNG+ +W  W L  +E   +        +V  KITW   T+Q V  + +++    +    +FDV     N K
Sbjct:   15 VIFQRMSVLTQR-----LNPITGQCDWEMQNELYDYHQEIARSAYADMLHDEERNRKYYEALKTAINKMHGRGKKANVLDIGTGTGLLSMMAVKCGADSVVACEGFKPMAQCAKQIIALNG-FSDDIKVVNKRSTELTVGKNGDLKERANILVTEVFDTELIGEGALGTFSHAHKELLESDCYVIPNAANVYAQVVESPVAANWNRLKDIFNSDGEKLLSVPNSIRTCHGAAAVHDIQLSQFPHELFNEVFPPQTVLRFDFSG-KTTFNFKRSNILTVKSQHDGLAQVVFMWWDLIMDPDNKIVLSCAPYWSHPLVKAGSDLKDVQIPWRDHWMQAVYYLPSEVKVKKDKELYFICCHDEYSLWFNLKKDLKLSNQDYLCSPICDCGVHIAFSRTRIGQLNDSVRTKKYINVLENCVTNDSQVLILSHGFYLGMVASKLGAKEVYYIEENVHIREILHS--------FIKFNKLSNVHIYEGVDELKKSVNVGNINVVFGEPFFVTTIVPWDSLHFCYLLEHFKDLLPE-NAVIIPQKVHIKIIAVHFQDLYKIRAPLINCEGFNMKPFDELITNSSQISDS-SVEAQPLWEYPGIALSEVTTIATINLKKFFEE-DVIENVGTINLQGNENCNGVAVWVDWFLDDSEKNIISTGPTIAPVVGKKITWDMHTRQGVCLLTDNEVRNSLNYSFIFDVIQGQINLK 700          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK-------ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQN-NKYHWRDHWLQAVFCVRN---LNENKNLQFQFSHDQFSIWIEMSDGKNGG--------KIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIG-TAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSL--ENL---NEISGACSFKSVDATDCNGLVLWAAWE-LTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPGEI------ILKLVFDVDNCNFNFKFGIN 2029
            F    N   G+ EW   D +YDYN E+  S Y DML+D  RN  Y   L+  I +++ + + VHVLDIG GSGLLSM+A++ GAD+VTACE F PM   A+ + +K N FSDKI +I   S DL  G   +M E+AN+LV+E+ DTELIGEG L T+ +A+K+L+T + + +P  AT Y Q++ESDF+ N   L+       E   +P+  S  + C G ++V DIQ S +   +F  + +PIK+    F +  +S   +   S+  +A       ++WW++ M  +++  +S  P W     +   WRDHW+QAV+       + + + +     HD++S+W ++   K G          +E+P C CG H+   R R+  +N R  S+   +   L +V   G T V +SD S+  + L+ A L  Q +I+ +++      +     +                   +  ++ +PY+  S+ PW +++FW+    +R +  G    + P +  + A+ ++F+DL ++  PV  ++GFD+   D+++  ++++ D    +   LWEY     S+   L+ FD+ QS+  ENL    EI   CS        CN + LW  ++ L +G    ++       + +  W P  +Q V+F++    P ++      + ++ F   +   +F+F I 
Sbjct:    4 FRQTLNPTTGRAEWTAMDEDYDYNQEVARSSYTDMLHDEERNKKYKAGLELAIGRVRGRGQRVHVLDIGTGSGLLSMLAVQAGADRVTACECFKPMAGAAQKI-VKTNSFSDKITVIPKRSTDLTAGPGGDMEERANILVAELLDTELIGEGCLYTYQHALKHLVTPDCIFVPHAATVYAQVVESDFMWNWHRLRDLPITGCEKALVPS--SDMEACMGAAAVHDIQLSQVKQEQFKPLTEPIKVFRFEFDKKMESLERRTELSVMVTATGQAQVVLMWWDIEMDPDSSVLLSVAPSWAHPTPDNMQWRDHWMQAVYFNHQSIPVEKGQQVALHGRHDEYSLWFQVQ--KQGSTTSAGSEFSLERPVCRCGGHMVWSRPRLGMLNDR--SRWGTYAAALKQVLAPGQTCVSVSDASW--VPLMAARLGAQELIEANNLQGKVHIVQGSEEQLEAALEDR----------KVGMVIAEPYYSSSLLPWHSLYFWYVCTRLRHKLQG-GATVLPARAELVAVAMEFEDLWRLRAPVGTVEGFDISVMDQMVKDHSNQTDER-VEPHPLWEYPGVGVSNPVTLMNFDLTQSVPTENLVATGEIPFTCS------GSCNAVALWMNYDLLGDGRHTVSTGPRAPYTSGRPQWDPHIRQGVYFMDK---PVQVSADFRLVYRVTFSPKDGRMDFQFDIE 667          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLN--MNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK------ENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHD-SFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKW------ICQNNKYH---------WRDHWLQAVFCV---RNLNENKNLQFQFSHDQFSIWIEMSDGK--NGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQL-LKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHF 1939
            FI   N + G + W   D NYDY+ EI  S +ADML+DH RN  YY  +K  I +     +  +VLDIG G+GLLSMMA K GAD +TACE+F PM +CA  ++ +N  F DKI LI+  S  + +G N  M +KAN+LV+E+FDTELIGEG LSTF +A +NLL EN ++IP  AT ++Q++ES  +   +W        +NKY+ N P   K+C G ++V DIQ +   +  F  +  P  +   + S      +++K C  +        ++  +WW+L M   N   +S  P W      I QN  +          WRDHW+QA++ +     +  N  +     HD++S+W ++ +         E+P CSC +H+   R RI Q+N  +Y++   ++  L  K++     + +SD     ++ +  G     +++ + + K   E+     E +         +      +I  I G+PYFI SI PW+N++FW+ +     Q   +     P+  TI  ++V+F+DLHKI  P+   +GFD+  FD++I  ++D++D    + + LWEY   A S    +  FD+ +++  + +I+ + +   +    CNG+ LW  W L   + + +          +I+W PFT+Q VH 
Sbjct:    4 FIQCLNPLTGTINWEEKDENYDYHQEIARSAFADMLHDHERNQKYYLGIKAAIEKKHQNGEEANVLDIGTGTGLLSMMAAKCGADSITACEAFTPMAKCAIKIIQENG-FEDKIKLIHKRSTKMTIGKNGDMVKKANILVTEVFDTELIGEGALSTFRHAHENLLEENSIVIPHSATIWVQVVESSAV--RAWNTICPIKVKNKYLLNTPHSVKSCSGAAAVHDIQLTQFPDDAFKPLLPPQPIFKFDLSGKSTLLYNEKRCLHVKPIINGTAHAIFMWWDLIMDVNNQVLLSCAPVWEHPDTKILQNKGFSLKTIADLIPWRDHWMQAIYYLPVETPVTVNNEVSLIGYHDEYSLWFQLINESINEAPDCERPVCSCNVHVAYCRTRIGQLN--DYTRNEKYIKVLEEKITPDTVCLCLSDGCLLGLAAIKLGAKKIFVLETNFLSKKCIEMFVKKNELSEKVEIIESVDNLPPENEINLIFGEPYFITSIVPWENLYFWYLISRYSSQIQRI-----PIAATIMGVIVEFNDLHKIRAPLGVCEGFDLSIFDKLIQTSSDKSDS-PVEVQPLWEYPTKALSLPFVIKKFDLTENVNEIEDINISETVPILTNGMCNGVALWIDWHLNSEITISSGPTVEVQSGTRISWDPFTRQGVHL 652          

Query:   50 FISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLN--MNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWL----KENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHD-SFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKW------ICQNNKYH---------WRDHWLQAVFCV---RNLNENKNLQFQFSHDQFSIWIEMSDGK--NGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQL-LKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHF 1939
            FI   N + G + W   D NYDY+ EI  S +ADML+DH RN  YY  +K  I +     +  +VLDIG G+GLLSMMA K GAD +TACE+F PM +CA  ++ +N  F DKI LI+  S  + +G N  M +KAN+LV+E+FDTELIGEG LSTF +A +NLL EN ++IP  AT ++Q++ES  +   + +     +NKY+ N P   K+C G ++V DIQ +   +  F  +  P  +   + S      +++K C  +        ++  +WW+L M   N   +S  P W      I QN  +          WRDHW+QA++ +     +  N  +     HD++S+W ++ +         E+P CSC +H+   R RI Q+N  +Y++   ++  L  K++     + +SD     ++ +  G     +++ + + K   E+     E +         +      +I  I G+PYFI SI PW+N++FW+ +     Q   +     P+  TI  ++V+F+DLHKI  P+   +GFD+  FD++I  ++D++D    + + LWEY   A S    +  FD+ +++  + +++ + +   +    CNG+ LW  W L   + + +          +I+W PFT+Q VH 
Sbjct:    4 FIQCLNPLTGTINWEEKDENYDYHQEIARSAFADMLHDHERNQKYYLGIKAAIEKKHQNGEEANVLDIGTGTGLLSMMAAKCGADSITACEAFTPMAKCAIKIIQENG-FEDKIKLIHKRSTKMTIGKNGDMVKKANILVTEVFDTELIGEGALSTFRHAHENLLEENSIVIPHSATIWVQVVESSAVCAWNTICPIKVKNKYLLNTPHSVKSCSGAAAVHDIQLTQFPDDAFKPLLPPQPIFKFDLSGKSTLLYNEKRCLHVKPIINGTAHAIFMWWDLIMDVNNQVLLSCAPVWEHPDTKILQNKGFSLKTIADLIPWRDHWMQAIYYLPVETPVTVNNEVSLIGYHDEYSLWFQLINESINEAPDCERPVCSCNVHVAYCRTRIGQLN--DYTRNEKYIKVLEEKITPDTICLCLSDGCLLGLAAIKLGAKKIFVLETNFLSKKCIEMFIKKNELSEKVEIIESVDNLPPENEINLIFGEPYFITSIVPWENLYFWYLISRYSSQIQRI-----PIAATIMGVIVEFNDLHKIRAPLGVCEGFDLSIFDKLIQASSDKSDS-PVEVQPLWEYPTKALSLPFVIKKFDLTENVNEIEDVNISETVPILTNGMCNGVALWIDWHLNSEITISSGPTVEVQSGTRISWDPFTRQGVHL 652          

Query:   44 RNFISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKE---NKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLC-FSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKWI-CQNNKYHWRDHWLQAVFCV---RNLNENKNLQFQFSHDQFSIWIEMSDGKNGG---KIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIGTAVV-ISDFSYFSI-----------SLVNAGLSIQTI---IDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESI-RKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINN 1948
            + F  + N   G ++W+     YDY+ EI  S YADML+D +RN  YY  ++  + ++K++ + V VLDIG G+GLLSMMA+  GAD     E F PM + A +++ KN  FSDKI +IN HS ++ VG   +M E+AN+LV+E+FDTELIGEG L ++++A  +L+ E    +P +AT Y Q++ES+ L + + ++    +    + P+  K C G  SV DIQ S +    F  IG    +  ++FS++    S   C +S  ++ +    + V+  WW+L M    +   S  PKW   +  +Y WRDHW+Q+V+ +   RN+ E + L     HD +S+W  + +           +P C+C  HL   R R  ++N  ++ +   +++ L  V    +  + +SD S   I           SL N+G++ Q I   ++ +SI    + L     + T                 I  ++G+PYF  S+ PW ++ FW+   ++ R  RPG   +I P   T+  + V+F DL +I  P    +GFD+ P DE++  + D  +    +   LWEY C A +    ++ FD +Q +     IS   +     +  C+G  LW  + LTE + +   L        +  W P  KQ V+F+  
Sbjct:    2 KTFCGRANPTTGGLDWVEESEEYDYHQEIARSCYADMLHDRDRNEKYYQGIRAAVSRVKARGERVVVLDIGTGTGLLSMMAVTAGADFCYGIEVFKPMAKAAASIVQKNG-FSDKIKVINKHSTEVTVGPDGDMQERANILVTELFDTELIGEGALPSYEHAHLHLMQEGCEAVPHRATIYAQVVESEHLWSWAQIRPVQVDDRTLHPPAAMKQCAGTPSVCDIQLSQVPPSAFTPIGPLCTMFSVDFSRM---VSSAPCSYSCKFTVQAGGRAQVVLSWWDLDMDPSGSIVCSMAPKWTYSEPREYPWRDHWMQSVYFLPTERNVCEGEKLSLTVFHDDYSLWYNLDERHQISADISSTRPCCTCQTHLVWTRPRFGELN--DWQRTDSYLSALRSVLRPDSVCLSVSDGSLLPIFAHMLGAKKVFSLENSGMTKQVIEQFLEANSIKNGVRLLAIRAEQLTAADLEEER---------ISVLIGEPYFSTSLLPWHSLFFWYCRTALARLLRPGA--IILPSSATLYLLAVEFQDLWRIRAPCGTCEGFDVSPMDEMVQQSLDFRESREAEPHHLWEYPCRALTKPHPVMTFDFQQCVPA-QPISSQGTLPLTGSGRCHGFALWMEYNLTEDITVSMGLTKPVGEEGECVWSPHRKQGVYFLQT 649          

Query:   44 RNFISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKE---NKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLC-FSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKWI-CQNNKYHWRDHWLQAVFCV---RNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIGTAVV-ISDFSYFSI-----------SLVNAGLSIQTI---IDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESI-RKQRPGVNYLISPVKMTIKAMLVKFDDLH--KINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINN 1948
            + F  + N   G ++W+     YDY+ EI  S YADML+D +RN  YY  ++  + ++K++ + V VLDIG G+GLLSMMA+  GAD     E F PM + A +++ KN  FSDKI +IN HS ++ VG   +M E+AN+LV+E+FDTELIGEG L ++++A  +L+ E    +P +AT Y Q++ES+ L + + ++    +    + P+  K C G  SV DIQ S +    F  IG    +  ++FS++    S   C +S  ++ +    + V+  WW+L M    +   S  PKW   +  +Y WRDHW+Q+V+ +   RN+ E + L     HD +S+W  + +     +  +P C+C  HL   R R  ++N  ++ +   +++ L  V    +  + +SD S   I           SL N+G++ Q I   ++ +SI    + L     + T                 I  ++G+PYF  S+ PW ++ FW+   ++ R  RPG   +I P   T+  + V+F  L+     +     K   M  F      + D  +    +   LWEY C A +    ++ FD +Q +     IS   +     +  C+G  LW  + LTE + +   L        +  W P  KQ V+F+  
Sbjct:    2 KTFCGRANPTTGGLDWVEESEEYDYHQEIARSCYADMLHDRDRNEKYYQGIRAAVSRVKARGERVVVLDIGTGTGLLSMMAVTAGADFCYGIEVFKPMAKAAASIVQKNG-FSDKIKVINKHSTEVTVGPDGDMQERANILVTELFDTELIGEGALPSYEHAHLHLMQEGCEAVPHRATIYAQVVESEHLWSWAQIRPVQVDDRTLHPPAAMKQCAGTPSVCDIQLSQVPPSAFTPIGPLCTMFSVDFSRM---VSSAPCSYSCKFTVQAGGRAQVVLSWWDLDMDPSGSIVCSMAPKWTYSEPREYPWRDHWMQSVYFLPTERNVCEGEKLSLTVFHDDYSLWYNLDE-----RSTRPCCTCQTHLVWTRPRFGELN--DWQRTDSYLSALRSVLRPDSVCLSVSDGSLLPIFAHMLGAKKVFSLENSGMTKQVIEQFLEANSIKNGVRLLAIRAEQLTAADLEEER---------ISVLIGEPYFSTSLLPWHSLFFWYCRTALARLLRPGA--IILPSSATLYLLAVEFQVLYCPYFCSQSSGQKRIQMCLF---FQQSLDFRESREAEPHHLWEYPCRALTKPHPVMTFDFQQCVPA-QPISSQGTLPLTGSGRCHGFALWMEYNLTEDITVSMGLTKPVGEEGECVWSPHRKQGVYFLQT 640          

Query:  155 LNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSE-IFDTELIGEGVLSTFDY---AIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKEN---KYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCVRNLNENKN 1000
            LND  R  +Y  AL+ V+R           L +  GS LL + A  LGA KV + E+   M +      L+ N   + + L+   +  L       E+ +VL+ E  F T L+    L  F Y   A+  LL    +I+P  AT YL  +E   L    +  ++   K I  +  F++    +    + +   L  Y    +  P  +   +F Q   +       ++P +     + + +W E  +T + T  +  + K + +  +  W  H  Q V+ ++  +E+  
Sbjct:  369 LNDWQRTDSYLSALRSVLRPDSV------CLSVSDGS-LLPIFAHMLGAKKVFSLENSG-MTKQVIEQFLEANSIKNGVRLLAIRAEQLTAADLEEERISVLIGEPYFSTSLLPWHSL-FFWYCRTALARLLRPGAIILPSSATLYLLAVEFQVLYCPYFCSQSSGQKRI-QMCLFFQQSLDFRESREAEPHHLWEYPCRALTKPHPVMTFDFQQCVPAQPISSQGTLPLTGSGRCHGFALWMEYNLTEDITVSMG-LTKPVGEEGECVWSPHRKQGVYFLQTPSESSG 646          

Query:  152 MLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIK-------------NLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNLPSFYKTCHGY-------SSVFDIQASLLTNYR-------FNFIGDPIKLKVINFSQIHDSFSDKLCFS------IPYSAENPFYSYVIWWELTMTSENTNCISTVPK 913
            MLNDH RN  Y  A+++ +     ++ F  VLDIG G+G+L M A K GA +V ACE    M+E    V+  NN+ +D I +++  S ++ +  ++ ++ +++V+E  D  L+GEG++ +  +A K             +  ++   +IP  AT +   +E   +  H  L     +P +        G        S   D  A   T  R       F  + +P ++  I+F+ + +   + LC S      +P + E    +  +W++L +  EN+  IST P+
Sbjct:  172 MLNDHGRNRKYQLAIQRAV-----QEGFSTVLDIGTGTGILGMCAKKAGASEVYACELSKTMYELGCEVVSANNM-ADSIKILHMKSLEMEIPKDIPKRVSLVVTETVDAGLLGEGIIESLIHAWKNLLLPPPNPEEPLSTPSQTGRVIPAGATVFGMAVECQEIRRHHRL----CVPAVGGLDLEAVGEIRSPVSCSVDADESAEPYTTERLSRLPGGFTALTEPCRVLDIDFNNVQE--LEGLCCSKTTRLRVPVTQEGVVDALAVWFQLHLDQENS--ISTGPQ 444          

Query:  152 MLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIK-------------NLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNLPSFYKTCHGY-------SSVFDIQASLLTNYR-------FNFIGDPIKLKVINFSQIHDSFSDKLCFS------IPYSAENPFYSYVIWWELTMTSENTNCISTVPK 913
            MLNDH RN  Y  A+++ +     ++ F  VLDIG G+G+L M A K GA +V ACE    M+E    V+  NN+ +D I +++  S ++ +  ++ ++ +++V+E  D  L+GEG++ +  +A K             +  ++   +IP  AT +   +E   +  H  L     +P +        G        S   D  A   T  R       F  + +P ++  I+F+ + +   + LC S      +P + E    +  +W++L +  EN+  IST P+
Sbjct:  172 MLNDHGRNRKYQLAIQRAV-----QEGFSTVLDIGTGTGILGMCAKKAGASEVYACELSKTMYELGCEVVSANNM-ADSIKILHMKSLEMEIPKDIPKRVSLVVTETVDAGLLGEGIIESLIHAWKNLLLPPPNPEEPLSTPSQTGRVIPAGATVFGMAVECQEIRRHHRL----CVPAVGGLDLEAVGEIRSPVSCSVDADESAEPYTTERLSRLPGGFTALTEPCRVLDIDFNNVQE--LEGLCCSKTTRLRVPVTQEGVVDALAVWFQLHLDQENS--ISTGPQ 444          

Query:  143 YADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHS---W-LKENKY---IPNLPSFYKTC--HGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVF 970
            + +ML D  R   Y  A+ +    +  K     VLD+G G+G+LS+   + GA +V A E+     + A+  +++ N   D++ +I       +  + + E+ +V+VSE     L+ E +L++   A    L    +I+P +A  ++  I SD +       W   + +Y   +  +  F ++C  +G  +V  +    + ++   F    + L+ +   ++        C     S+ N   +  +W+ +T  +E+      +P  +   + +    HW QAV 
Sbjct:   43 HEEMLADTVRTDTYRRAIFRCAAALAGKA----VLDVGAGTGVLSVFCAQAGARRVYAVEASSIAEQAAR--IVRQNRVEDRVQVI----RGTVESVELPERVDVIVSEWMGYALLHESMLNSVITARDRWLKPGGLILPERAELFVAPI-SDLVAEERLNFWDTVKGQYGVDMSCMAEFARSCVLNGEIAVHPVTVEDVLSHPCRFA--QLDLRTVTLEELKRVSGAFCCQCFGSSSLN---ALCVWFTVTFPAED------MPPLVLSTSPFKAETHWKQAVL 305          

Query: 1403 IVGDPYFIYSIFPWDNIHFWFAVESIRKQ-RPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQ 1876
            ++G+P+F  S+ PW +++FW+A  ++    RP    L    ++ I  M V+F DL +I  P+ + +GFD+   D ++  +    +    +   LWEY C A S     + F   + + +   +    S     +  C+ +V+W  + LT+ + +   L+
Sbjct:  101 LLGEPFFTTSLLPWHSLYFWYARSALAPLLRPDAAVLPRAARLFI--MAVQFQDLWRIRAPIGECEGFDVSIMDHMVQRSLSYRESAEAEPHALWEYPCRALSAPLATLHFPFTELVPD-EPLGATGSLPLCRSGTCHAVVMWMEYLLTDELHIMTGLK 256          

Query:  149 DMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKE 631
            +M+ D+ R   Y  A+ Q     + K     VLD+GCGSG+LS  A++ GA KV A E+   M + A+ VL+++N   D+I +I     D    +++ +K +V++SE     L  E +L ++ +A K  L  N  + P     +L    + F D   ++++
Sbjct:  137 NMMQDYIRTGTYQRAILQNHADFRDKI----VLDVGCGSGILSFFAVQAGARKVYAVEA-SSMAQHAE-VLVRSNNLQDRIVVIPGKVED----VSIPDKVDVIISEPMGYMLFNERMLESYLHA-KKWLKPNGNMFPTLGDVHL----APFTDEQLYMEQ 282          

Query:   71 VNGKMEWL------LTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLI---NCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNLPSFYKTCHGY--SSVFD--IQASLLTNYRFNFIGDPIKLK----VINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVF 970
            VNG +E        +T  +Y ++       + +ML D  R   Y +A+       K K     VLD+G G+G+L M A K GA KV   E  + + + ++ ++  NNL  D +  I        DL+V     +K ++++SE     L+ E +L+T   A    L     I P +A+ +L  IE           + +Y  N  ++++  +G+  S + D  IQ  L+       + +P ++     ++    I+    D L F+ P+  +     YV       T E T C          +  Y    HW Q VF
Sbjct:   13 VNGSVEGTAPNADEMTSKDYYFDSYAHFGIHEEMLKDEVRTRTYRNAMYHNRHLFKDKV----VLDVGSGTGILCMFAAKAGAKKVFGIECSN-IADYSQQIIKANNL--DSVITIVKGKVEEVDLLV-----DKVDIIISEWMGYCLLYESMLNTVICARDKWLKPGGAIFPDRASLFLTAIE-----------DRQYKENKINWWEDVYGFDMSCIRDVAIQEPLVD------VVEPKQVVTNSCLVKEVDIYTVKVDDLTFTSPFCLQVRRADYVHALVAYFTVEFTRCHKRTGFSTAPDAPY---THWKQTVF 297          

Query:  143 YADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIE 595
            + +ML D  R  +Y +A+ Q     K K     VLD+GCG+G+LSM A K GA  V   +    + E AK  L++ N FSDKI L+     D+ +      K ++++SE     L+ E ++ T  YA  + L E  +I P K + +L  +E
Sbjct:   33 HEEMLQDTVRTLSYRNAIIQNKDLFKDKI----VLDVGCGTGILSMFAAKHGAKHVIGVD-MSSIIEMAKE-LVELNGFSDKITLLRGKLEDVHLPF---PKVDIIISEWMGYFLLYESMMDTVLYARDHYLVEGGLIFPDKCSIHLAGLE 174          

Query:  152 MLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTE--------------------NPVIIPFKATFYLQIIESDFLDNHSWLKEN 634
            MLND  RN  Y  A+   +           VLDIG GSG+LSM A++ GA KV ACE    M+E +K+VLL N + S  I++I+  S DL++G ++  + +++ +E  D  L+GEG+L T  +A + LL E                    +P++IP  A  Y Q+IES  + + S+ + N
Sbjct:  140 MLNDRQRNLAYKKAISNAV-----SNGCDIVLDIGSGSGILSMFAVQAGAKKVYACEMSKTMYELSKDVLLGNQMES-FIEVIHKKSTDLLIGKDLPGRVSLVCTETLDCGLLGEGILKTISHAWEALLQEKKSITSTEQQIDGVVRTSGISPMVIPRGAKLYGQVIESSDIRHQSYCRPN 314          

Query: 1403 IVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLIS--PVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDY--------ICFDSKFLWEYDCFARSDVKELIVFDMRQSL 1750
            ++ +P+F  S+FPW NIHFW+AV SIR+    VN  I   P   T++AM V+F DL K + PV  ++GFD+  FD +I G+   N+         I  +   +WEY C   +   ++  FD RQ +
Sbjct:    4 VISEPFFSASLFPWHNIHFWYAVTSIRRH---VNKDIKVLPQGGTLRAMAVEFKDLWKYHAPVGVVEGFDVSHFDHLIQGSKSANEMMDGHHDNCIALEPHHVWEYPCKPLTQPFDIAHFDFRQPI 126          

Query:   95 LTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIE 595
            +T  +Y ++       + +ML D  R   Y +++       + K     VLD+GCG+G+LSM A K GA  V A E    + + +K ++  NN F   I LI     D+ + +   EK ++++SE     L  E +L T  YA    L  + ++ P KA  Y+  IE
Sbjct:   56 MTSADYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHLFRDKI----VLDVGCGTGILSMFAAKAGAKHVYAIE-MSSIVDYSKTIIKDNN-FDSVITLIKGKVEDVELPV---EKVDIIISEWMGYCLFYESMLDTVLYARDKWLKPDGMLFPDKAKLYVCAIE 213          

Query:  143 YADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLG-ADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYL 583
            + +ML D  R  +Y  A++Q     K K     VLD+GCG+G+LS+   + G A KV A E+ + + +  + ++ +NNL  DKI +I       I  + + EK +++VSE   T L+ E +L +   A    L  N ++ P +A  +L
Sbjct:   79 HLEMLKDKPRTESYRMAIEQGAGYFKDKV----VLDVGCGTGILSLFCAREGKASKVYAVEASE-IAKLTEEIIKQNNL-DDKITVIQGK----IEEVELPEKVDIIVSEWMGTFLVFEFMLESVLTARDIWLKPNGLVWPSEAKLFL 216          

Query:  143 YADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQII 592
            + +ML D  R  +Y D +       K K     VLD+GCG+G+LSM A + GA +V   +  + +++     +++ N F   I LI   + ++ + +   E+ +V++SE     L+ E +L T  +     L     + P K T +L  I
Sbjct:  233 HEEMLKDKVRTESYRDFIYGNPDIFKDKV----VLDVGCGTGILSMFAARSGARQVIGIDQSEIIYQAMD--IIRENGFEKTITLIKGKAEEVTLPV---EQVDVIISEWMGYFLLFESMLDTVLFCRDKWLNPQGSVYPDKCTMHLVAI 373          

Query:   44 RNFISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK--ENKYIPNL-PSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQ-IHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKWICQNNKYH-WRDHWLQAVFCV---RNLNENKNLQFQFSHDQFSIWIEM-----SDGKNGGKIEKPFCSCGLHLHIPRNRIYQMN-SREYSKQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCD-----IIGIVGDPYFIYSIFPWDNIHFWFAVESIRK-QRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFI-----NNHKFPGEIILKLVFDVDNCNFNFKFGIN 2029
            + F  + N   G ++W+     YDY+ EI  S YADML+DH+RN  YY  +++ + ++K++ + V VLDIG G+GLLSMMA+  GAD   A E F PM E A++++ +N  FSDKI +IN HS D+ VG   +M  +AN+L++E+FDTELIGEG L ++++A ++L+ E    +P +AT Y Q++ES+ L   + L+  E K +  L P     C G  SV DIQ S ++   F  +     +  ++FS+ +  +F      S  + A       V+  WW+L M        +  P W   + K   WRDHW+Q+V+ +     + E  +L     HD +S+W  +      D +      +P C+C  HL   R R  ++N  R     +  +  +LK   +   + +SD S   +     G      ++N  + K   E V      T       +        D     I  ++G+PYF  S+ PW ++ FW+   ++    RP    L  P   ++  + V+F DL +I       +GFD+ P DE++  + D  +    +   LWEY C A +     + FD  Q + +   IS   S   +    C G+ LW  ++LT+ + +   L +         W    KQAV+F+     ++      +     F+ D+ +    F I+
Sbjct:    2 KTFCGRANPTTGALDWVEESEEYDYHQEIARSCYADMLHDHDRNEKYYQGIREAVARLKARGEKVIVLDIGTGTGLLSMMAVTAGADFCYAVEVFKPMAEAAQSIVERNG-FSDKIKIINKHSTDVTVGAGGDMPTRANLLITELFDTELIGEGALPSYEHAHQHLVQEGCEAVPHRATVYAQLVESELLWGWAQLQPMEVKGVRLLPPPAVSRCAGAHSVCDIQLSQVSPASFKPLSPLCTMFSVDFSKPVSSAFQSH---SAQFVARCSGRGQVVLSWWDLHMDPRGDVVCTMAPSWTYPHQKRAPWRDHWMQSVYFLPEESKVTEGDDLCLTVCHDDYSLWYSLQAHSRQDQQTEAPPPRPSCTCQAHLVWTRPRFGELNDGRRTESYVQALRSVLKEDAV--CLSVSDGSLLPVFAHKLGAKKVYSLENSRMSKQLIEQVLGANAITGGVELLEIRADHLTRNDLGDEQISVLMGEPYFSTSLLPWHSLFFWYCRTALSGLLRPDATIL--PCSASLHVVAVEFQDLWRIRARCGRCEGFDVTPMDEMVQRSLDFRESREAEPHPLWEYPCRALTQSATAMTFDFTQCVPS-QPISCQGSLPLIRTGCCQGVALWMEYQLTDDITVSTGLTAPISEQGDCEWSRHRKQAVYFLRSPWQSSGDGRAAVSYSFTFEPDSGDIKMDFSIS 683          

Query:   44 RNFISKFNLVNGKMEWLLTDNNYDYNDEI---RTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGL--NMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLK--ENKYIPNL-PSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQ-IHDSFSDKLCFSIPYSAENPFYSYVI--WWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCV---RNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMN-SREYSKQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRK-QRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFI-----NNHKFPGEIILKLVFDVDNCNFNFKFGIN 2029
            + F  + N   G ++W+     YDY+ EI   + S Y  ++ D  +N  YY  +++ + ++K++ + V VLDIG G+GLLSMMA+  GAD   A E F PM E A++++ +N  FSDKI +IN HS D+ VG   +M  +AN+L++E+FDTELIGEG L ++++A ++L+ E    +P +AT Y Q++ES+ L   + L+  E K +  L P     C G  SV DIQ S ++   F  +     +  ++FS+ +  +F      S  + A       V+  WW+L M        +  P W   + K  WRDHW+Q+V+ +     + E  +L     HD +S+W  + D +      +P C+C  HL   R R  ++N  R     +  +  +LK   +   + +SD S   +     G      ++N  + K   E     T +  +               I  ++G+PYF  S+ PW ++ FW+   ++    RP    L  P   ++  + V+F DL +I       +GFD+ P DE++  + D  +    +   LWEY C A +     + FD  Q + +   IS   S   +    C G+ LW  ++LT+ + +   L +         W    KQAV+F+     ++      +     F+ D+ +    F I+
Sbjct:    2 KTFCGRANPTTGALDWVEESEEYDYHQEIARVKVSIYILIMLDFFQNEKYYQGIREAVARLKARGEKVIVLDIGTGTGLLSMMAVTAGADFCYAVEVFKPMAEAAQSIVERNG-FSDKIKIINKHSTDVTVGAGGDMPTRANLLITELFDTELIGEGALPSYEHAHQHLVQEGCEAVPHRATVYAQLVESELLWGWAQLQPMEVKGVRLLPPPAVSRCAGAHSVCDIQLSQVSPASFKPLSPLCTMFSVDFSKPVSSAFQSH---SAQFVARCSGRGQVVLSWWDLHMDPRGDVVCTMAPSWTYPHQK-RWRDHWMQSVYFLPEESKVTEGDDLCLTVCHDDYSLWYSLQDQQTEAPPPRPSCTCQAHLVWTRPRFGELNDGRRTESYVQALRSVLKEDAV--CLSVSDGSLLPVFAHKLGAKKVYSLENSRMSKQLIEQKPEPTVSRLS--------------QISVLMGEPYFSTSLLPWHSLFFWYCRTALSGLLRPDATIL--PCSASLHVVAVEFQDLWRIRARCGRCEGFDVTPMDEMVQRSLDFRESREAEPHPLWEYPCRALTQSATAMTFDFTQCVPS-QPISCQGSLPLIRTGCCQGVALWMEYQLTDDITVSTGLTAPISEQGDCEWSRHRKQAVYFLRSPWQSSGDGRAAVSYSFTFEPDSGDIKMDFSIS 660          

Query:  152 MLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLL-------------TENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYR----------FNFIGDPIKLKVINFSQIHD----SFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPK 913
            MLNDH RN  Y  A+++ ++   S      VLDIG G+G+L M A + GA +V ACE    M+E A  V+  N +  D I +++  S ++ V  ++  + +++V+E  D  L GEG++ +  +A  +LL             +    +IP  AT +   +E   +  H  L   +      +     H   S        +  Y           +  + +P     I+F+ + +    S  +     +P + +    +  +W++L +  E++  +ST P+
Sbjct:  159 MLNDHGRNQKYQQAIQKAVQSGCST-----VLDIGTGTGILGMCAKQAGAAEVYACELSKTMYELACEVVTANGMEGD-IKILHKKSLEMEVPADIPHRVSLVVTETVDAGLFGEGIIESLIHAWHHLLLPPKSNENKFGEQSATGRVIPAGATVFALAVECPEIRRHHRLCATQVGGLSMAACGEIHSPVSCSSEPEESVEPYTTERLSRLPGGYTALTEPFTALTIDFNNVQELEGLSSREVQRIQLPVTQQGELDALAVWFQLHLDEESS--LSTGPQ 431          

Query:  143 YADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDN--HSW 622
            + +M+ DH R   Y  A+      ++ K     VLD+G G+G+LS+   + GA KV A E+   + E A+ ++ +NN+  D+I++I       +  + + EK +V+VSE     L+ E +L++   A    L    +I+P +A  Y+  I    +++  H W
Sbjct:   39 HEEMIADHVRTNTYRTAILLNTECIRGKV----VLDVGAGTGVLSIFCAQAGARKVYAVEACS-ISEQAEKIVRQNNM-DDRIEVI----RGTVESVELPEKVDVIVSEWMGYALLHESMLNSVLCARDRWLRPGGIILPSRAELYIAPICDPVVEDRLHFW 190          

Query:   47 NFISKFNLVNGKMEWLLTDNNYDYNDEIRTSGYADM-LNDHNRNCNYYDALKQVIRQMKSKKKFVH---------VLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYI 643
            N + +F    G+ E +LT  N   +     S +  M L  HN  C   + L+  +R    +K F+          VLD+  GSG+LS  A++ GA +V A ES  P+ E  + +L++ N  S++I ++       +  L++    +++VSE     L+   ++  F +A +  L  N ++ P  A  +L    + F D   +L++N  +
Sbjct:   30 NLLLQFTSSTGQFEGVLTLVNLLRSSRDDGSKFLTMSLQVHNYLCQQQNLLRDYLRTATYQKAFLANEDDFKDKVVLDVCSGSGILSFFAIQAGASRVYAVES-SPVAEYIQ-ILVRANRLSEQIVILEGQ----VEQLSLPVMVDIIVSEPMGCLLLSGRLMERFLHA-RRWLKPNGLMFPSCADLHL----APFSDEQLYLEQNARV 227          

Query:   83 MEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCVRNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPGEIILKLVFDVDNCNFNFKFGINE 2032
            MEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCVRNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQL KVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSILKLTKELVELNTENTNNYSFSSLENFSSFNCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATD NGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFI+NHKFPGEIILKLVFDVDNCNFNFKFGINE
Sbjct:    1 MEWLLTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCVRNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLFKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSILKLTKELVELNTENTNNYSFSSLENFSSFNCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDSNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFISNHKFPGEIILKLVFDVDNCNFNFKFGINE 650          

Query:  437 MNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCVRNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPGEIILKLVFDVDNCNFNFKFGINE 2032
            MNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCVRNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQL KVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSILKLTKELVELNTENTNNYSFSSLENFSSFNCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATD NGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFI+NHKFPGEIILKLVFDVDNCNFNFKFGINE
Sbjct:    1 MNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIESDFLDNHSWLKENKYIPNLPSFYKTCHGYSSVFDIQASLLTNYRFNFIGDPIKLKVINFSQIHDSFSDKLCFSIPYSAENPFYSYVIWWELTMTSENTNCISTVPKWICQNNKYHWRDHWLQAVFCVRNLNENKNLQFQFSHDQFSIWIEMSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLFKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSILKLTKELVELNTENTNNYSFSSLENFSSFNCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDSNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFISNHKFPGEIILKLVFDVDNCNFNFKFGINE 532          

Query: 1046 MSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLLKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDCNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFINNHKFPGEIILKLVFDVDNCNFNFKFGINE 2032
            MSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQL KVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSILKLTKELVELNTENTNNYSFSSLENFSSFNCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATD NGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFI+NHKFPGEIILKLVFDVDNCNFNFKFGINE
Sbjct:    1 MSDGKNGGKIEKPFCSCGLHLHIPRNRIYQMNSREYSKQIDFVTQLFKVSHIGTAVVISDFSYFSISLVNAGLSIQTIIDNDSILKLTKELVELNTENTNNYSFSSLENFSSFNCDIIGIVGDPYFIYSIFPWDNIHFWFAVESIRKQRPGVNYLISPVKMTIKAMLVKFDDLHKINTPVKDIKGFDMKPFDEIINGNTDENDYICFDSKFLWEYDCFARSDVKELIVFDMRQSLENLNEISGACSFKSVDATDSNGLVLWAAWELTEGVWMDNSLQSIDIVNNKITWKPFTKQAVHFISNHKFPGEIILKLVFDVDNCNFNFKFGINE 329          

Query:   95 LTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIE 595
            +T  +Y ++       + +ML D  R   Y +AL      +K K     VLD+GCG+G+L M A+K GA KV   +  + + + AK + +K N   DKI LI     ++ +  ++  K ++++SE     L  E +L+T  +A    L    +I+P KAT +L  IE
Sbjct:   16 MTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNALYHNKHLVKDKV----VLDVGCGTGILCMFAVKAGARKVIGIDCSN-IIDYAKEI-IKANKMEDKITLIKGKVEEVELPDDV-LKVDIIISEWMGYCLFYESMLNTVLFARDKWLKTGGIIMPDKATLHLCAIE 175          

Query:   95 LTDNNYDYNDEIRTSGYADMLNDHNRNCNYYDALKQVIRQMKSKKKFVHVLDIGCGSGLLSMMALKLGADKVTACESFDPMFECAKNVLLKNNLFSDKIDLINCHSNDLIVGLNMNEKANVLVSEIFDTELIGEGVLSTFDYAIKNLLTENPVIIPFKATFYLQIIE 595
            +T  +Y ++       + +ML D  R  +Y +AL      +K K     VLD+GCG+G+L M A++ GA +V   +  + + + AK + +K N    KI LI     ++ +  ++  K +V++SE     L+ E +L+T  +A    L    +I+P KAT ++  IE
Sbjct:    6 MTAKDYYFDSYAHFGIHEEMLKDEIRTISYRNALYHNEHLVKDKV----VLDVGCGTGILCMFAVRAGAKRVIGIDCSN-IIDYAKEI-VKANKMDTKITLIKGKVEEVELPADV-LKVDVIISEWMGYCLLYESMLNTVLFARDKWLAPGGIIMPDKATLHMVAIE 165