forkhead box A-1

Overview


Name	forkhead box A-1 (AFJ24799.1)
Smed ID	SMED30027428
Length (bp)	2149

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of forkhead box A-1 (SMED30027428) t-SNE clustered cells

Violin plots show distribution of expression levels for forkhead box A-1 (SMED30027428) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of forkhead box A-1 (SMED30027428) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for forkhead box A-1 (SMED30027428) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Expression Details

forkhead box A-1 ( foxA1 ) is expressed during Stage 3, Stage 4, Stage 5, Stage 6, Stage 7 and Stage 8 in the embryonic digestive system, pharynx, digestive system, embryonic pharynx and pharynx progenitor cell

Click to see image symbols and abbreviations


Abbreviation or symbol	Definition
O	oral hemisphere
A	aboral hemisphere
D	dorsal
V	ventral
L	lateral
black arrowhead	embryonic pharynx
red arrowhead	definitive pharynx
black arrows	primitive gut
yellow arrows	primitive ectoderm cells
cyan arrows	brain
cyan arrowheads	nerve cords
blue arrowheads	eye progenitors (trail cells)
purple arrowheads	eyes
scale bar	100 µm

Anatomical Expression

PAGE et. al., 2020

SMED30027428

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 36

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
parapharyngeal region	SMED30027428	h1SMcG0000282	SmedASXL_000307	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
parapharyngeal region	SMED30027428	h1SMcG0000282	SmedASXL_015256	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pharynx progenitor cell	SMED30027428	h1SMcG0000283	SMED30019774	smed_20140614	PMID:29906446 Zeng et al., 2018
pharynx progenitor cell	SMED30027428	h1SMcG0000282	SMED30027428	smed_20140614	PMID:29906446 Zeng et al., 2018
pharynx progenitor cell	SMED30027428	h1SMcG0000282	SMED30019774	smed_20140614	PMID:29906446 Zeng et al., 2018
pharynx	SMED30027428	h1SMcG0000283	dd_Smed_v4_10718_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30027428	h1SMcG0000283	dd_Smed_v4_10718_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30027428	h1SMcG0000283	dd_Smed_v4_10718_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30027428	h1SMcG0000283	dd_Smed_v4_10718_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30027428	h1SMcG0000283	dd_Smed_v4_10718_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30027428	h1SMcG0000283	dd_Smed_v4_10718_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30027428	h1SMcG0000283	dd_Smed_v4_10718_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30027428	h1SMcG0000283	dd_Smed_v6_10718_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
pharynx	SMED30027428	h1SMcG0000282	SMED30027428	smed_20140614	PMID:28072387 Davies et al., 2017
pharynx	SMED30027428	h1SMcG0000282	SMED30027428	smed_20140614	PMID:28072387 Davies et al., 2017
pharynx	SMED30027428	h1SMcG0000282	SMED30027428	smed_20140614	PMID:28072387 Davies et al., 2017
embryonic pharynx	SMED30027428	h1SMcG0000282	SMED30027428	smed_20140614	PMID:28072387 Davies et al., 2017
embryonic pharynx	SMED30027428	h1SMcG0000282	SMED30027428	smed_20140614	PMID:28072387 Davies et al., 2017
embryonic pharynx	SMED30027428	h1SMcG0000282	SMED30027428	smed_20140614	PMID:28072387 Davies et al., 2017
pharynx	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
pharynx	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
pharynx	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
embryonic pharynx	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
embryonic pharynx	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
embryonic pharynx	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:28072387 Davies et al., 2017
pharynx	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:25254346 Scimone et al., 2014
parenchyma	SMED30027428	h1SMcG0000282	Contig49549	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
parenchyma	SMED30027428	h1SMcG0000282	Contig49549	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
head region	SMED30027428	h1SMcG0000282	OX_Smed_1.0.21372	ox_Smed_v2	PMID:24238224 Kao et al., 2013
pharynx	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:27074666 Lander et al., 2016
prepharyngeal region	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:27074666 Lander et al., 2016
parapharyngeal region	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:27074666 Lander et al., 2016
pharynx	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:24737865 Adler et al., 2014
pharynx nerve plexus	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:24737865 Adler et al., 2014
pharynx musculature	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:24737865 Adler et al., 2014
pharynx epithelium	SMED30027428	h1SMcG0000282	JX010556.1	smed_ncbi_20240424	PMID:24737865 Adler et al., 2014

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of forkhead box A-1 vs. Ensembl Human
Match: FOXA1 (forkhead box A1 [Source:HGNC Symbol;Acc:HGNC:5021])

HSP 1 Score: 215.312 bits (547), Expect = 1.464e-61
Identity = 94/118 (79.66%), Postives = 103/118 (87.29%), Query Frame = 1

Query:  832 RDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            R +     + + ++RSY HAKPPYSYISLITMAIQ +P  M TLSEIYQ+IMD FPYYRQNQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGSYWTLHP SGNMFENGCYLRRQKRFK
Sbjct:  150 RSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFK 267

[Close]

BLAST of forkhead box A-1 vs. Ensembl Human
Match: FOXA2 (forkhead box A2 [Source:HGNC Symbol;Acc:HGNC:5022])

HSP 1 Score: 211.46 bits (537), Expect = 2.573e-60
Identity = 97/128 (75.78%), Postives = 106/128 (82.81%), Query Frame = 1

Query:  802 ELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            + GL R+  P+           Y+RSYTHAKPPYSYISLITMAIQ SP  M TLSEIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RSP+KPGKGS+WTLHP SGNMFENGCYLRRQKRFK
Sbjct:  139 QAGLSRARDPKT----------YRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK 256

[Close]

BLAST of forkhead box A-1 vs. Ensembl Human
Match: FOXA2 (forkhead box A2 [Source:HGNC Symbol;Acc:HGNC:5022])

HSP 1 Score: 211.46 bits (537), Expect = 2.737e-60
Identity = 97/128 (75.78%), Postives = 106/128 (82.81%), Query Frame = 1

Query:  802 ELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            + GL R+  P+           Y+RSYTHAKPPYSYISLITMAIQ SP  M TLSEIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RSP+KPGKGS+WTLHP SGNMFENGCYLRRQKRFK
Sbjct:  145 QAGLSRARDPKT----------YRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK 262

[Close]

BLAST of forkhead box A-1 vs. Ensembl Human
Match: FOXA3 (forkhead box A3 [Source:HGNC Symbol;Acc:HGNC:5023])

HSP 1 Score: 203.756 bits (517), Expect = 9.884e-59
Identity = 93/121 (76.86%), Postives = 102/121 (84.30%), Query Frame = 1

Query:  868 YQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAAT 1230
            Y+R   HAKPPYSYISLITMAIQ +P  M TLSEIYQ+IMD FPYYR+NQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGSYW LHP SGNMFENGCYLRRQKRFK    ++ +    AAT
Sbjct:  109 YRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKL-EEKVKKGGSGAAT 228

[Close]

BLAST of forkhead box A-1 vs. Ensembl Human
Match: FOXB1 (forkhead box B1 [Source:HGNC Symbol;Acc:HGNC:3799])

HSP 1 Score: 176.407 bits (446), Expect = 5.421e-49
Identity = 74/108 (68.52%), Postives = 90/108 (83.33%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            RP + +Y+  KPPYSYISL  MAIQ+SP  M  LSEIY+FIMD FPYYR+N QRWQNS+RH+LSFNDCF+K+ R P++PGKGS+W LHP  G+MFENG +LRR+KRFK
Sbjct:    3 RPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFK 110

[Close]

BLAST of forkhead box A-1 vs. Ensembl Celegans
Match: pha-4 (Defective pharyngeal development protein 4 [Source:UniProtKB/Swiss-Prot;Acc:Q17381])

HSP 1 Score: 190.274 bits (482), Expect = 1.588e-53
Identity = 90/143 (62.94%), Postives = 108/143 (75.52%), Query Frame = 1

Query:  796 GLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA 1224
            G+  G G+  + ++  +++   R +  +Y  +KPPYSYISLITMAIQ S     TLSEIY +IMD FPYY+ NQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGS+WTLH   GNMFENGCYLRRQKRFK   RE  R+ + A
Sbjct:  110 GVSGGQGQELTIQEFETVTEKIRRH-GTYGQSKPPYSYISLITMAIQKSNSRQLTLSEIYNWIMDLFPYYQNNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSFWTLHEHCGNMFENGCYLRRQKRFKVKEREPSRKKRNA 251

[Close]

BLAST of forkhead box A-1 vs. Ensembl Celegans
Match: pha-4 (Defective pharyngeal development protein 4 [Source:UniProtKB/Swiss-Prot;Acc:Q17381])

HSP 1 Score: 191.045 bits (484), Expect = 1.667e-53
Identity = 90/143 (62.94%), Postives = 108/143 (75.52%), Query Frame = 1

Query:  796 GLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA 1224
            G+  G G+  + ++  +++   R +  +Y  +KPPYSYISLITMAIQ S     TLSEIY +IMD FPYY+ NQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGS+WTLH   GNMFENGCYLRRQKRFK   RE  R+ + A
Sbjct:  141 GVSGGQGQELTIQEFETVTEKIRRH-GTYGQSKPPYSYISLITMAIQKSNSRQLTLSEIYNWIMDLFPYYQNNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSFWTLHEHCGNMFENGCYLRRQKRFKVKEREPSRKKRNA 282

[Close]

BLAST of forkhead box A-1 vs. Ensembl Celegans
Match: pha-4 (Defective pharyngeal development protein 4 [Source:UniProtKB/Swiss-Prot;Acc:Q17381])

HSP 1 Score: 192.2 bits (487), Expect = 2.779e-53
Identity = 90/143 (62.94%), Postives = 108/143 (75.52%), Query Frame = 1

Query:  796 GLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA 1224
            G+  G G+  + ++  +++   R +  +Y  +KPPYSYISLITMAIQ S     TLSEIY +IMD FPYY+ NQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGS+WTLH   GNMFENGCYLRRQKRFK   RE  R+ + A
Sbjct:  205 GVSGGQGQELTIQEFETVTEKIRRH-GTYGQSKPPYSYISLITMAIQKSNSRQLTLSEIYNWIMDLFPYYQNNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSFWTLHEHCGNMFENGCYLRRQKRFKVKEREPSRKKRNA 346

[Close]

BLAST of forkhead box A-1 vs. Ensembl Celegans
Match: lin-31 (pep chromosome:WBcel235:II:3982549:3986944:1 gene:WBGene00003017.1 transcript:K10G6.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-31)

HSP 1 Score: 142.124 bits (357), Expect = 4.137e-38
Identity = 62/101 (61.39%), Postives = 77/101 (76.24%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYL 1164
            RP + SY   KPPYSYI L  MAIQ+S   M  L+EIY++IMD FP+YR+N QRWQNS+RH+LSFNDCF+K+ R  ++PGKGSYW +HP +  MFENG  L
Sbjct:    3 RPGKDSYDEQKPPYSYIWLTYMAIQDSDDKMLPLTEIYKYIMDRFPFYRKNTQRWQNSLRHNLSFNDCFIKIPRRADRPGKGSYWAVHPNASGMFENGSCL 103

[Close]

BLAST of forkhead box A-1 vs. Ensembl Celegans
Match: unc-130 (pep chromosome:WBcel235:II:11281986:11283953:1 gene:WBGene00006853.1 transcript:C47G2.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:unc-130)

HSP 1 Score: 144.436 bits (363), Expect = 7.480e-38
Identity = 63/104 (60.58%), Postives = 79/104 (75.96%), Query Frame = 1

Query:  874 RSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            R  +HAKPPYSYI+LI M+I NSP    TLSEI +FI++ F YY++    WQNSIRH+LS NDCFVKV+R P  PGKG+YW L P   +MF+NG +LRR+KR+K
Sbjct:  121 RKSSHAKPPYSYIALIAMSILNSPEKKLTLSEICEFIINKFEYYKEKFPAWQNSIRHNLSLNDCFVKVARGPGNPGKGNYWALDPNCEDMFDNGSFLRRRKRYK 224

[Close]

BLAST of forkhead box A-1 vs. Ensembl Fly
Match: fkh (gene:FBgn0000659 transcript:FBtr0300259)

HSP 1 Score: 224.172 bits (570), Expect = 7.385e-65
Identity = 107/159 (67.30%), Postives = 119/159 (74.84%), Query Frame = 1

Query:  805 LGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA-------ATGPGSNVTENN 1260
            LG  R D P            Y+RSYTHAKPPYSYISLITMAIQN+P  M TLSEIYQFIMD FP+YRQNQQRWQNSIRHSLSFNDCFVK+ R+P+KPGKGS+WTLHP SGNMFENGCYLRRQKRFKD  +E  RQ  ++       AT PG    E++
Sbjct:  191 LGRSRVDKPTT----------YRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDS 339

[Close]

BLAST of forkhead box A-1 vs. Ensembl Fly
Match: fkh (gene:FBgn0000659 transcript:FBtr0345227)

HSP 1 Score: 224.172 bits (570), Expect = 7.385e-65
Identity = 107/159 (67.30%), Postives = 119/159 (74.84%), Query Frame = 1

Query:  805 LGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA-------ATGPGSNVTENN 1260
            LG  R D P            Y+RSYTHAKPPYSYISLITMAIQN+P  M TLSEIYQFIMD FP+YRQNQQRWQNSIRHSLSFNDCFVK+ R+P+KPGKGS+WTLHP SGNMFENGCYLRRQKRFKD  +E  RQ  ++       AT PG    E++
Sbjct:  191 LGRSRVDKPTT----------YRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDS 339

[Close]

BLAST of forkhead box A-1 vs. Ensembl Fly
Match: fkh (gene:FBgn0000659 transcript:FBtr0085321)

HSP 1 Score: 224.172 bits (570), Expect = 7.385e-65
Identity = 107/159 (67.30%), Postives = 119/159 (74.84%), Query Frame = 1

Query:  805 LGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA-------ATGPGSNVTENN 1260
            LG  R D P            Y+RSYTHAKPPYSYISLITMAIQN+P  M TLSEIYQFIMD FP+YRQNQQRWQNSIRHSLSFNDCFVK+ R+P+KPGKGS+WTLHP SGNMFENGCYLRRQKRFKD  +E  RQ  ++       AT PG    E++
Sbjct:  191 LGRSRVDKPTT----------YRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDS 339

[Close]

BLAST of forkhead box A-1 vs. Ensembl Fly
Match: fkh (gene:FBgn0000659 transcript:FBtr0346765)

HSP 1 Score: 224.172 bits (570), Expect = 9.634e-65
Identity = 107/159 (67.30%), Postives = 119/159 (74.84%), Query Frame = 1

Query:  805 LGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA-------ATGPGSNVTENN 1260
            LG  R D P            Y+RSYTHAKPPYSYISLITMAIQN+P  M TLSEIYQFIMD FP+YRQNQQRWQNSIRHSLSFNDCFVK+ R+P+KPGKGS+WTLHP SGNMFENGCYLRRQKRFKD  +E  RQ  ++       AT PG    E++
Sbjct:  191 LGRSRVDKPTT----------YRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDS 339

[Close]

BLAST of forkhead box A-1 vs. Ensembl Fly
Match: fkh (gene:FBgn0000659 transcript:FBtr0330333)

HSP 1 Score: 224.942 bits (572), Expect = 1.498e-63
Identity = 107/159 (67.30%), Postives = 119/159 (74.84%), Query Frame = 1

Query:  805 LGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA-------ATGPGSNVTENN 1260
            LG  R D P            Y+RSYTHAKPPYSYISLITMAIQN+P  M TLSEIYQFIMD FP+YRQNQQRWQNSIRHSLSFNDCFVK+ R+P+KPGKGS+WTLHP SGNMFENGCYLRRQKRFKD  +E  RQ  ++       AT PG    E++
Sbjct:  191 LGRSRVDKPTT----------YRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDS 339

[Close]

BLAST of forkhead box A-1 vs. Ensembl Zebrafish
Match: foxa1 (forkhead box A1 [Source:ZFIN;Acc:ZDB-GENE-990415-78])

HSP 1 Score: 221.09 bits (562), Expect = 2.437e-64
Identity = 103/141 (73.05%), Postives = 116/141 (82.27%), Query Frame = 1

Query:  850 SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK------DPHREIGRQSQRAATG-PGSNVT 1251
            + +N+ ++RSY HAKPPYSYISLITMAIQ +P  M TLSEIYQ+IMD FPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSP+KPGKGSYWTLHP SGNMFENGCYLRRQKRFK      D  R  G++ Q + +G P S+ T
Sbjct:  143 ARDNKTFRRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCDKKLPDGKRSEGKREQSSGSGSPASDST 283

[Close]

BLAST of forkhead box A-1 vs. Ensembl Zebrafish
Match: foxa2 (forkhead box A2 [Source:NCBI gene;Acc:30126])

HSP 1 Score: 212.616 bits (540), Expect = 1.758e-61
Identity = 110/193 (56.99%), Postives = 131/193 (67.88%), Query Frame = 1

Query:  850 SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRF-------KDPHREIGRQSQRAAT-------GPGSNVTENNHDNASQE-------ASDNAESDTKPNIKQLDLSSDLLTNQGH 1365
            S + + Y+RSYTHAKPPYSYISLITMAIQ SP  M TLSEIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RSP+KPGKGS+WTLHP SGNMFENGCYLRRQKRF       KDP R+       +++        P SN + N H  +  +       + D+A S T      L   + +L ++GH
Sbjct:  137 SRDPKTYRRSYTHAKPPYSYISLITMAIQQSPSKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCDKKLSKDPSRKTSEGGSNSSSESCNGNESPHSNSSSNEHKRSLSDMKSGQGLSPDHAASPTSQAQHLLAQHNSVLAHEGH 329

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BLAST of forkhead box A-1 vs. Ensembl Zebrafish
Match: foxa3 (forkhead box A3 [Source:ZFIN;Acc:ZDB-GENE-980526-423])

HSP 1 Score: 211.075 bits (536), Expect = 1.347e-60
Identity = 110/192 (57.29%), Postives = 126/192 (65.62%), Query Frame = 1

Query:  826 SPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRF--------------------KDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNIKQLDLSS 1341
            SP   N      +PY+RS THAKPPYSYISLITMAIQ S   M TL+EIYQ+IMD FPYYR+NQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGSYW LHP SGNMFENGCYLRRQKRF                    K  H   G Q + + T  GS+  E+ H ++S   S + E     ++ QLD  S
Sbjct:  121 SPTSLNRTKEMPKPYRRSLTHAKPPYSYISLITMAIQQSQSKMLTLNEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPNSGNMFENGCYLRRQKRFKIEEKAGKKSSSKSQDGSSTKGTHSSEGMQEEHSPTT-GSDGAESAHSDSSHAGSTSEEQQR--SLVQLDCPS 309

[Close]

BLAST of forkhead box A-1 vs. Ensembl Zebrafish
Match: foxa (forkhead box A sequence [Source:ZFIN;Acc:ZDB-GENE-990415-76])

HSP 1 Score: 188.348 bits (477), Expect = 1.873e-53
Identity = 83/106 (78.30%), Postives = 91/106 (85.85%), Query Frame = 1

Query:  868 YQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            Y+R+ +HAKPPYSYISLI MAIQ SP    TL+EIY +I   FPYYRQNQQRWQNSIRHSLSFNDCFV+V RSP+ PGKGSYW LHP SGNMFENGCY+RRQKRFK
Sbjct:   68 YRRTLSHAKPPYSYISLICMAIQQSPAKRLTLNEIYDWIRQLFPYYRQNQQRWQNSIRHSLSFNDCFVRVPRSPDSPGKGSYWALHPDSGNMFENGCYMRRQKRFK 173

[Close]

BLAST of forkhead box A-1 vs. Ensembl Zebrafish
Match: foxa (forkhead box A sequence [Source:ZFIN;Acc:ZDB-GENE-990415-76])

HSP 1 Score: 187.963 bits (476), Expect = 2.366e-53
Identity = 83/106 (78.30%), Postives = 91/106 (85.85%), Query Frame = 1

Query:  868 YQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            Y+R+ +HAKPPYSYISLI MAIQ SP    TL+EIY +I   FPYYRQNQQRWQNSIRHSLSFNDCFV+V RSP+ PGKGSYW LHP SGNMFENGCY+RRQKRFK
Sbjct:   68 YRRTLSHAKPPYSYISLICMAIQQSPAKRLTLNEIYDWIRQLFPYYRQNQQRWQNSIRHSLSFNDCFVRVPRSPDSPGKGSYWALHPDSGNMFENGCYMRRQKRFK 173

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BLAST of forkhead box A-1 vs. Ensembl Xenopus
Match: xk (X-linked Kx blood group [Source:Xenbase;Acc:XB-GENE-1005584])

HSP 1 Score: 217.238 bits (552), Expect = 9.361e-63
Identity = 99/134 (73.88%), Postives = 113/134 (84.33%), Query Frame = 1

Query:  850 SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQ---RAATGPGS 1242
            + + + ++RSY HAKPPYSYISLITMAIQ +P  M TLSEIYQ+IMD FPYYRQNQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGSYWTLHP SGNMFENGCYLRRQKRFK   ++ G+ SQ   +  +GP S
Sbjct:  144 TRDTKTFRRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQQGGKGSQDGRKDVSGPSS 277

[Close]

BLAST of forkhead box A-1 vs. Ensembl Xenopus
Match: foxa2 (forkhead box A2 [Source:NCBI gene;Acc:395063])

HSP 1 Score: 212.616 bits (540), Expect = 5.573e-61
Identity = 94/112 (83.93%), Postives = 102/112 (91.07%), Query Frame = 1

Query:  850 SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            S + + Y+RSYTHAKPPYSYISLITMAIQ SP  M TLSEIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RSP+KPGKGS+WTLHP SGNMFENGCYLRRQKRFK
Sbjct:  135 SRDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFK 246

[Close]

BLAST of forkhead box A-1 vs. Ensembl Xenopus
Match: ventx1.2 (VENT homeobox 1, gene 2 [Source:Xenbase;Acc:XB-GENE-920868])

HSP 1 Score: 210.69 bits (535), Expect = 1.150e-60
Identity = 94/121 (77.69%), Postives = 106/121 (87.60%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA 1224
            R Y+R+Y+HAKPPYSYISLITMAIQ +P  M TL+EIYQ+I+D FPYYRQNQQRWQNSIRHSLSFNDCFVKV RSPEKPGKGSYWTLHP+SGNMFENGCYLRRQKRFK    + G + ++ 
Sbjct:  109 RTYRRNYSHAKPPYSYISLITMAIQQAPNKMMTLNEIYQWIIDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVPRSPEKPGKGSYWTLHPESGNMFENGCYLRRQKRFKCERSKSGEREKKV 229

[Close]

BLAST of forkhead box A-1 vs. Ensembl Xenopus
Match: serpinc1 (serpin peptidase inhibitor, clade C (antithrombin), member 1 [Source:Xenbase;Acc:XB-GENE-975782])

HSP 1 Score: 172.17 bits (435), Expect = 1.686e-47
Identity = 73/108 (67.59%), Postives = 89/108 (82.41%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            RP + +Y+  KPPYSYISL  MAIQ+S   M  LSEIY+FIMD FPYYR+N QRWQNS+RH+LSFNDCF+K+ R P++PGKGS+W LHP  G+MFENG +LRR+KRFK
Sbjct:    3 RPGRNTYSDQKPPYSYISLTAMAIQSSQEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFK 110

[Close]

BLAST of forkhead box A-1 vs. Ensembl Xenopus
Match: FOXB2 (forkhead box B2 [Source:NCBI gene;Acc:101730239])

HSP 1 Score: 156.377 bits (394), Expect = 2.618e-42
Identity = 67/101 (66.34%), Postives = 82/101 (81.19%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYL 1164
            RP + SY+  KPPYSYISL  MAIQ+S   M  LS+IY+FIMD FPYYR+N QRWQNS+RH+LSFNDCF+K+ R P++PGKGS+W LHP  G+MFENG +L
Sbjct:    3 RPGKSSYSEQKPPYSYISLTAMAIQSSQEKMLPLSDIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPDCGDMFENGSFL 103

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BLAST of forkhead box A-1 vs. Ensembl Mouse
Match: Foxa2 (forkhead box A2 [Source:MGI Symbol;Acc:MGI:1347476])

HSP 1 Score: 219.55 bits (558), Expect = 2.087e-63
Identity = 107/177 (60.45%), Postives = 124/177 (70.06%), Query Frame = 1

Query:  802 ELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAA------TGPGSNVTENNHDNASQEASDNAESDTKP 1314
            + GL R+  P+           Y+RSYTHAKPPYSYISLITMAIQ SP  M TLSEIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RSP+KPGKGS+WTLHP SGNMFENGCYLRRQKRFK   +   +++  AA      T PGS  ++     A+  AS+       P
Sbjct:  139 QAGLSRARDPKT----------YRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAASSGGKKTAPGSQASQAQLGEAAGSASETPAGTESP 305

[Close]

BLAST of forkhead box A-1 vs. Ensembl Mouse
Match: Foxa2 (forkhead box A2 [Source:MGI Symbol;Acc:MGI:1347476])

HSP 1 Score: 219.164 bits (557), Expect = 2.623e-63
Identity = 107/177 (60.45%), Postives = 124/177 (70.06%), Query Frame = 1

Query:  802 ELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAA------TGPGSNVTENNHDNASQEASDNAESDTKP 1314
            + GL R+  P+           Y+RSYTHAKPPYSYISLITMAIQ SP  M TLSEIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RSP+KPGKGS+WTLHP SGNMFENGCYLRRQKRFK   +   +++  AA      T PGS  ++     A+  AS+       P
Sbjct:  145 QAGLSRARDPKT----------YRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAASSGGKKTAPGSQASQAQLGEAAGSASETPAGTESP 311

[Close]

BLAST of forkhead box A-1 vs. Ensembl Mouse
Match: Foxa1 (forkhead box A1 [Source:MGI Symbol;Acc:MGI:1347472])

HSP 1 Score: 214.927 bits (546), Expect = 1.389e-61
Identity = 94/118 (79.66%), Postives = 103/118 (87.29%), Query Frame = 1

Query:  832 RDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            R +     + + ++RSY HAKPPYSYISLITMAIQ +P  M TLSEIYQ+IMD FPYYRQNQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGSYWTLHP SGNMFENGCYLRRQKRFK
Sbjct:  150 RSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFK 267

[Close]

BLAST of forkhead box A-1 vs. Ensembl Mouse
Match: Foxa3 (forkhead box A3 [Source:MGI Symbol;Acc:MGI:1347477])

HSP 1 Score: 204.142 bits (518), Expect = 6.126e-59
Identity = 90/106 (84.91%), Postives = 96/106 (90.57%), Query Frame = 1

Query:  868 YQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            Y+R   HAKPPYSYISLITMAIQ +P  M TLSEIYQ+IMD FPYYR+NQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGSYW LHP SGNMFENGCYLRRQKRFK
Sbjct:  111 YRRPLAHAKPPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFK 216

[Close]

BLAST of forkhead box A-1 vs. Ensembl Mouse
Match: Foxb1 (forkhead box B1 [Source:MGI Symbol;Acc:MGI:1927549])

HSP 1 Score: 176.407 bits (446), Expect = 4.033e-49
Identity = 74/108 (68.52%), Postives = 90/108 (83.33%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            RP + +Y+  KPPYSYISL  MAIQ+SP  M  LSEIY+FIMD FPYYR+N QRWQNS+RH+LSFNDCF+K+ R P++PGKGS+W LHP  G+MFENG +LRR+KRFK
Sbjct:    3 RPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFK 110

[Close]

BLAST of forkhead box A-1 vs. UniProt/SwissProt
Match: sp|Q17241|SGF1_BOMMO (Silk gland factor 1 OS=Bombyx mori OX=7091 GN=SGF1 PE=2 SV=1)

HSP 1 Score: 225.328 bits (573), Expect = 5.000e-66
Identity = 102/133 (76.69%), Postives = 115/133 (86.47%), Query Frame = 1

Query:  826 SPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA 1224
            SP      + N++ Y+RSYTHAKPPYSYISLITMAIQN+P  M TLSEIYQFIMD FP+YRQNQQRWQNSIRHSLSFNDCFVKV R+P+KPGKGS+WTLHP SGNMFENGC+LRRQKRFKD  +E  RQ+Q+A
Sbjct:   91 SPTSALQRARNDKTYRRSYTHAKPPYSYISLITMAIQNNPSRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKVPRTPDKPGKGSFWTLHPDSGNMFENGCFLRRQKRFKDEKKETLRQAQKA 223

[Close]

BLAST of forkhead box A-1 vs. UniProt/SwissProt
Match: sp|P14734|FKH_DROME (Protein fork head OS=Drosophila melanogaster OX=7227 GN=fkh PE=1 SV=1)

HSP 1 Score: 224.172 bits (570), Expect = 7.402e-64
Identity = 107/159 (67.30%), Postives = 119/159 (74.84%), Query Frame = 1

Query:  805 LGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRA-------ATGPGSNVTENN 1260
            LG  R D P            Y+RSYTHAKPPYSYISLITMAIQN+P  M TLSEIYQFIMD FP+YRQNQQRWQNSIRHSLSFNDCFVK+ R+P+KPGKGS+WTLHP SGNMFENGCYLRRQKRFKD  +E  RQ  ++       AT PG    E++
Sbjct:  191 LGRSRVDKPTT----------YRRSYTHAKPPYSYISLITMAIQNNPTRMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKIPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDEKKEAIRQLHKSPSHSSLEATSPGKKDHEDS 339

[Close]

BLAST of forkhead box A-1 vs. UniProt/SwissProt
Match: sp|P35583|FOXA2_MOUSE (Hepatocyte nuclear factor 3-beta OS=Mus musculus OX=10090 GN=Foxa2 PE=1 SV=2)

HSP 1 Score: 219.55 bits (558), Expect = 1.460e-62
Identity = 107/177 (60.45%), Postives = 124/177 (70.06%), Query Frame = 1

Query:  802 ELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAA------TGPGSNVTENNHDNASQEASDNAESDTKP 1314
            + GL R+  P+           Y+RSYTHAKPPYSYISLITMAIQ SP  M TLSEIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RSP+KPGKGS+WTLHP SGNMFENGCYLRRQKRFK   +   +++  AA      T PGS  ++     A+  AS+       P
Sbjct:  139 QAGLSRARDPKT----------YRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAASSGGKKTAPGSQASQAQLGEAAGSASETPAGTESP 305

[Close]

BLAST of forkhead box A-1 vs. UniProt/SwissProt
Match: sp|O42097|FOXA2_ORYLA (Hepatocyte nuclear factor 3-beta OS=Oryzias latipes OX=8090 GN=foxa2 PE=2 SV=1)

HSP 1 Score: 216.468 bits (550), Expect = 5.632e-62
Identity = 104/162 (64.20%), Postives = 120/162 (74.07%), Query Frame = 1

Query:  850 SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRF--------KDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTK 1311
            S + + Y+RSYTHAKPPYSYISLITMAIQ SP  M TL+EIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RSP+KPGKGS+WTLHP SGNMFENGCYLRRQKRF        K+P R+ G      ++    N  E+ H N+S      + SD K
Sbjct:  136 SRDPKTYRRSYTHAKPPYSYISLITMAIQQSPSKMLTLAEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKKMSMKEPGRKGGDGGSANSSSDSCNGNESPHSNSSSGEHKRSLSDMK 297

[Close]

BLAST of forkhead box A-1 vs. UniProt/SwissProt
Match: sp|P32315|FXA1B_XENLA (Forkhead box protein A1-B OS=Xenopus laevis OX=8355 GN=foxa1-b PE=2 SV=1)

HSP 1 Score: 214.927 bits (546), Expect = 2.881e-61
Identity = 99/138 (71.74%), Postives = 114/138 (82.61%), Query Frame = 1

Query:  805 LGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQ 1218
            +G G ++  R ++S     + ++RSY HAKPPYSYISLITMAIQ +P  M TLSEIYQ+IMD FPYYRQNQQRWQNSIRHSLSFNDCF+KVSRSP+KPGKGSYWTLHP SGNMFENGCYLRRQKRFK    + G+ +Q
Sbjct:  133 MGYGATNINRTRDS-----KTFRRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFIKVSRSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKTQGGKGNQ 265

[Close]

BLAST of forkhead box A-1 vs. TrEMBL
Match: I1ZIE5 (Forkhead box A-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 905.975 bits (2340), Expect = 0.000e+0
Identity = 485/485 (100.00%), Postives = 485/485 (100.00%), Query Frame = 1

Query:  571 MLGKNPYETAMSNVYSLPPGGSIYNMNPMSISSAGYNSQQVSTLSLNLTGIGPHSLXXXXXXXXXXXXXXXXXRQGLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNIKQLDLSSDLLTNQGHNIKNTNPTSVSQSCSMFHRKKENCSPVEMKLXXXXXXXXXXEHPQIHYNPNQQFYSNQQNIFQQSSLDHYSLLASDDPLGQGMHLPPGANSVFGLYGAHNLPNDDQISVSLPSISLSGHPYDNLSTAMAYQYEASQHNSSLLTTSNPFSIDRLMHPRLVAAAMGVSPHDTLYAGATGPSVDLEHMKXXXXXXXXXXXXXAMSDYYKYVQNPQPGNSDMSL 2025
            MLGKNPYETAMSNVYSLPPGGSIYNMNPMSISSAGYNSQQVSTLSLNLTGIGPHSLSPMSASMSGIAAMAGGMRQGLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNIKQLDLSSDLLTNQGHNIKNTNPTSVSQSCSMFHRKKENCSPVEMKLNNQNQQSNQQEHPQIHYNPNQQFYSNQQNIFQQSSLDHYSLLASDDPLGQGMHLPPGANSVFGLYGAHNLPNDDQISVSLPSISLSGHPYDNLSTAMAYQYEASQHNSSLLTTSNPFSIDRLMHPRLVAAAMGVSPHDTLYAGATGPSVDLEHMKYYSNYNNVPPYSSAMSDYYKYVQNPQPGNSDMSL
Sbjct:    1 MLGKNPYETAMSNVYSLPPGGSIYNMNPMSISSAGYNSQQVSTLSLNLTGIGPHSLSPMSASMSGIAAMAGGMRQGLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNIKQLDLSSDLLTNQGHNIKNTNPTSVSQSCSMFHRKKENCSPVEMKLNNQNQQSNQQEHPQIHYNPNQQFYSNQQNIFQQSSLDHYSLLASDDPLGQGMHLPPGANSVFGLYGAHNLPNDDQISVSLPSISLSGHPYDNLSTAMAYQYEASQHNSSLLTTSNPFSIDRLMHPRLVAAAMGVSPHDTLYAGATGPSVDLEHMKYYSNYNNVPPYSSAMSDYYKYVQNPQPGNSDMSL 485

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BLAST of forkhead box A-1 vs. TrEMBL
Match: Q9NDK9 (Winged helix/forkhead transcription factor DjFoxA OS=Dugesia japonica OX=6161 GN=DjFoxA PE=2 SV=1)

HSP 1 Score: 835.099 bits (2156), Expect = 0.000e+0
Identity = 449/486 (92.39%), Postives = 467/486 (96.09%), Query Frame = 1

Query:  571 MLGKNPYETAMSNVYSLPPGGSIYNMNPMSISSAGYNSQQVSTLSLNLTGIGPHSLXXXXXXXXXXXXXXXXXRQGLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNIKQLDLSSDLLTNQGHNIKNTNPTSVSQSCSMFHRKKENCSPVEMKLXXXXXXXXXXEHPQIHYNPNQQFYSNQQNIFQQSSLDHYSLLASDDPLGQGMHLPPGANSVFGLYGAHNLPNDDQISVSLPSISLSGHPYDNLSTAMAYQYEASQHNSSLLTTSNPFSIDRLMHPRLV-AAAMGVSPHDTLYAGATGPSVDLEHMKXXXXXXXXXXXXXAMSDYYKYVQNPQPGNSDMSL 2025
            M+GKNPYETAMSNVYSLPPGGSIYNMNPMSISSAGYNSQQV TLSLNL+GIGPHSLSPMSASMSGIAAMAGGMRQGL+LGL RSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAA GPGSN TENNHDNASQEASDNAESDTKPNIKQLDLSSDLLTNQGHNIKN+ PTS SQ+C MFHRKKENCSPVEMK+NNQ QQ  QQ+H Q+HYNPNQQFYSNQQNIFQQS+L+HY+L ASDDPLGQGMHLP GA+SVFGLYG HNL N+DQISVSLPSISLSGHPYDNLSTAMAYQYEASQHNSSLLTTSNPFSIDRLMHP LV AAAMG+SPHD+LYA ATG SVDLEHMKYYSNY+NVPPYS+AM+DYYKYVQNPQPGNSDMSL
Sbjct:    1 MIGKNPYETAMSNVYSLPPGGSIYNMNPMSISSAGYNSQQVPTLSLNLSGIGPHSLSPMSASMSGIAAMAGGMRQGLDLGLSRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAAAGPGSNATENNHDNASQEASDNAESDTKPNIKQLDLSSDLLTNQGHNIKNSIPTSASQTCPMFHRKKENCSPVEMKMNNQPQQPTQQQHQQLHYNPNQQFYSNQQNIFQQSTLEHYALSASDDPLGQGMHLPQGASSVFGLYG-HNLQNEDQISVSLPSISLSGHPYDNLSTAMAYQYEASQHNSSLLTTSNPFSIDRLMHPSLVAAAAMGLSPHDSLYAAATGSSVDLEHMKYYSNYSNVPPYSTAMADYYKYVQNPQPGNSDMSL 485

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BLAST of forkhead box A-1 vs. TrEMBL
Match: D3J1K2 (FoxA (Fragment) OS=Schmidtea polychroa OX=50054 GN=foxA PE=2 SV=1)

HSP 1 Score: 389.423 bits (999), Expect = 8.534e-129
Identity = 182/183 (99.45%), Postives = 183/183 (100.00%), Query Frame = 1

Query:  790 RQGLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNIKQLDLS 1338
            RQGLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSN+TENNHDNASQEASDNAESDTKPNIKQLDLS
Sbjct:   15 RQGLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNITENNHDNASQEASDNAESDTKPNIKQLDLS 197

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BLAST of forkhead box A-1 vs. TrEMBL
Match: A0A1B6CCN2 (Fork-head domain-containing protein OS=Clastoptera arizonana OX=38151 GN=g.30564 PE=4 SV=1)

HSP 1 Score: 235.343 bits (599), Expect = 1.550e-66
Identity = 112/185 (60.54%), Postives = 141/185 (76.22%), Query Frame = 1

Query:  802 ELGLGRSDSPRDKNSI--SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNIKQLDLSSDLL 1350
            +LG   + SP    ++  +  ++ Y+RSYTHAKPPYSYISLITMAIQNSP+ M TLSEIYQFIMD FP+YRQNQQRWQNSIRHSLSFNDCFVKV R+P+KPGKGS+WTLHP+SGNMFENGCYLRRQKRFKD  +E  R + ++ + PG ++  ++HD   ++  D  +   K ++  L L S +L
Sbjct:  117 DLGSADAGSPNSAAALQRARTDKSYRRSYTHAKPPYSYISLITMAIQNSPIKMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKVPRTPDKPGKGSFWTLHPESGNMFENGCYLRRQKRFKDEKKEASRSTHKSVS-PGQHLHIHHHD--IEKKGDKLD---KVSVSDLGLQSSML 295

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BLAST of forkhead box A-1 vs. TrEMBL
Match: A0A224XIG3 (Putative forkhead/hnf-3-related transcription factor (Fragment) OS=Panstrongylus lignarius OX=156445 PE=4 SV=1)

HSP 1 Score: 228.409 bits (581), Expect = 5.234e-66
Identity = 103/144 (71.53%), Postives = 119/144 (82.64%), Query Frame = 1

Query:  808 GLGRSDSPRDKNSI---SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAAT 1230
             +G + SP    ++   +  ++ Y+RSYTHAKPPYSYISLITMAIQNSP  M TLSEIYQFIMD FP+YRQNQQRWQNSIRHSLSFNDCFVKV R+P+KPGKGS+WTLHP SGNMFENGCYLRRQKRFKD  +E  RQS ++ +
Sbjct:  103 AIGETVSPSSVAALQRAARTDKSYRRSYTHAKPPYSYISLITMAIQNSPTKMLTLSEIYQFIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKVPRTPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKDDKKEAQRQSHKSVS 246

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BLAST of forkhead box A-1 vs. Ensembl Cavefish
Match: foxa1 (forkhead box A1 [Source:ZFIN;Acc:ZDB-GENE-990415-78])

HSP 1 Score: 216.853 bits (551), Expect = 2.668e-63
Identity = 96/112 (85.71%), Postives = 103/112 (91.96%), Query Frame = 1

Query:  850 SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            + +N+ ++RSY HAKPPYSYISLITMAIQ SP  M TLSEIYQ+IMD FPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSP+KPGKGSYWTLHP SGNMFENGCYLRRQKRFK
Sbjct:  125 ARDNKTFRRSYPHAKPPYSYISLITMAIQQSPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFK 236

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BLAST of forkhead box A-1 vs. Ensembl Cavefish
Match: foxa3 (hepatocyte nuclear factor 3-gamma [Source:NCBI gene;Acc:103043939])

HSP 1 Score: 216.083 bits (549), Expect = 1.890e-62
Identity = 111/209 (53.11%), Postives = 138/209 (66.03%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSN--------VTENNHDNASQEASDNAESDT----------KPNIKQLDL---SSDLLTNQGHNIKNTNPTSVSQSCSMFHRK 1425
            +PY+RS THAKPPYSYISLITMAIQ S   M TL+EIYQ+IMD FPYYR+NQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGSYW LHP SGNMFENGCYLRRQKRFK   +   +      +  G N        + E++   A  + +D+A+SD           + N+  LD    ++ L      +I ++ PTS+S + S  H +
Sbjct:  132 KPYRRSLTHAKPPYSYISLITMAIQQSGSKMLTLNEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPNSGNMFENGCYLRRQKRFKIEDKSAKKSGSSGKSQEGGNGKNEHQDGIQEDHSPAAGSDGADSAQSDASHPGSVSEEQQRNLVPLDCPSQATSLTHGSPLSIPSSVPTSMSTASSHLHSQ 340

[Close]

BLAST of forkhead box A-1 vs. Ensembl Cavefish
Match: foxa2 (forkhead box A2 [Source:NCBI gene;Acc:103033433])

HSP 1 Score: 207.223 bits (526), Expect = 1.286e-59
Identity = 98/153 (64.05%), Postives = 118/153 (77.12%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNI 1320
            + Y+RSYTHAKPPYSYISLITMAIQ S   M TL+EIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RSP+KPGKGS+WTLHP SGNMFENGCYLRRQKRFK   + + ++S R   G G N   +   ++  +    +E+  +P +
Sbjct:  125 KAYRRSYTHAKPPYSYISLITMAIQQSSSKMLTLNEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKC-EKLLEKESNRKE-GEGENSKGSPQPSSPTKDQKRSEAKARPAL 275

[Close]

BLAST of forkhead box A-1 vs. Ensembl Cavefish
Match: foxa (hepatocyte nuclear factor 3-gamma-like [Source:NCBI gene;Acc:103028902])

HSP 1 Score: 187.578 bits (475), Expect = 3.586e-52
Identity = 81/106 (76.42%), Postives = 93/106 (87.74%), Query Frame = 1

Query:  868 YQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            Y+R+++H+KPPYSYISLI MAIQ SP    TL+EIY +I   FPYYRQNQQRWQNSIRHSLSFNDCF++V RSPE PGKGS+WTLHP SGNMFENGCY+RRQKRF+
Sbjct:   94 YRRTFSHSKPPYSYISLIYMAIQQSPTKKLTLNEIYDWIRQLFPYYRQNQQRWQNSIRHSLSFNDCFIRVPRSPESPGKGSFWTLHPDSGNMFENGCYMRRQKRFR 199

[Close]

BLAST of forkhead box A-1 vs. Ensembl Cavefish
Match: foxb1a (forkhead box B1 [Source:NCBI gene;Acc:103044512])

HSP 1 Score: 174.866 bits (442), Expect = 8.014e-49
Identity = 73/108 (67.59%), Postives = 89/108 (82.41%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            RP + +Y+  KPPYSYISL  MAIQ+ P  M  LSEIY+FIMD FPYYR+N QRWQNS+RH+LSFNDCF+K+ R P++PGKGS+W LHP  G+MFENG +LRR+KRFK
Sbjct:    3 RPGRNTYSDQKPPYSYISLTAMAIQSCPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFK 110

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BLAST of forkhead box A-1 vs. Ensembl Sea Lamprey
Match: foxa2 (forkhead box A2 [Source:NCBI gene;Acc:30126])

HSP 1 Score: 203.371 bits (516), Expect = 2.590e-58
Identity = 97/148 (65.54%), Postives = 115/148 (77.70%), Query Frame = 1

Query:  808 GLGRSDSPRDKNSISN------NNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK-DPHREIGRQSQRAAT 1230
            G+G + SP      +N      +++ Y+R+YTHAKPPYSYISLITMAIQ S   M TL+EIY +IMD FP+YRQNQQRWQNSIRHSLSFNDCFVKV RSP+KPGKGS+W LHP SGNMFENGCYLRRQKRFK D  +++ +   R+ T
Sbjct:  127 GVGAAVSPMGGYGQANLANRARDSKVYRRNYTHAKPPYSYISLITMAIQQSTHKMMTLNEIYSWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFVKVPRSPDKPGKGSFWALHPDSGNMFENGCYLRRQKRFKCDRKQKMPQDGSRSPT 274

[Close]

BLAST of forkhead box A-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005206.1 (pep scaffold:Pmarinus_7.0:GL479371:8768:18483:1 gene:ENSPMAG00000004735.1 transcript:ENSPMAT00000005206.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 196.823 bits (499), Expect = 7.710e-58
Identity = 90/121 (74.38%), Postives = 101/121 (83.47%), Query Frame = 1

Query:  868 YQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAAT 1230
            Y+RSYTHAKPPYSYISLITMAIQ S   M TL+EIY +I D FP+YRQNQQRWQNSIRHSLSFNDCFVKV RSP+KPGKGS+W LHP SGNMFENGCYLRRQKRFK   +   + ++ A +
Sbjct:  147 YRRSYTHAKPPYSYISLITMAIQQSSGKMLTLNEIYSWITDLFPFYRQNQQRWQNSIRHSLSFNDCFVKVPRSPDKPGKGSFWALHPDSGNMFENGCYLRRQKRFKCDKKGTPKTARSACS 267

[Close]

BLAST of forkhead box A-1 vs. Ensembl Sea Lamprey
Match: foxb2 (forkhead box B2 [Source:ZFIN;Acc:ZDB-GENE-081104-320])

HSP 1 Score: 170.629 bits (431), Expect = 1.621e-47
Identity = 72/108 (66.67%), Postives = 89/108 (82.41%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            RP + +Y+  KPPYSYISL  MAIQ+S   M  LSEIY+FIM+ FPYYR+N QRWQNS+RH+LSFNDCF+K+ R P++PGKGS+W LHP  G+MFENG +LRR+KRFK
Sbjct:    3 RPGRNTYSDQKPPYSYISLTAMAIQSSAEKMLPLSEIYKFIMERFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPACGDMFENGSFLRRRKRFK 110

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BLAST of forkhead box A-1 vs. Ensembl Sea Lamprey
Match: FOXC2 (forkhead box C2 [Source:HGNC Symbol;Acc:HGNC:3801])

HSP 1 Score: 147.517 bits (371), Expect = 2.198e-41
Identity = 67/101 (66.34%), Postives = 80/101 (79.21%), Query Frame = 1

Query:  865 PYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLR 1167
            P+Q      KPPYSYI+LITMAIQ++P    TL+ IYQFIMD FP+YR+N+Q WQNSIRH+LS N+CFVKV R  +KPGKGSYW+L P S NMFENG +LR
Sbjct:   68 PHQAPKDLVKPPYSYIALITMAIQSAPDKKVTLNGIYQFIMDKFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWSLDPDSYNMFENGSFLR 168

[Close]

BLAST of forkhead box A-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002547.1 (pep scaffold:Pmarinus_7.0:GL485262:1354:7435:1 gene:ENSPMAG00000002324.1 transcript:ENSPMAT00000002547.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 138.272 bits (347), Expect = 2.405e-37
Identity = 60/92 (65.22%), Postives = 70/92 (76.09%), Query Frame = 1

Query:  889 AKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYL 1164
             KPPYSYI+LI MAIQNS     TLS IYQFI   FP+YR+N+Q WQNSIRH+LS N+CFV V+R   +PGKGS+WTL P S  MFENG +L
Sbjct:   25 VKPPYSYIALIAMAIQNSAEGRATLSAIYQFIAGRFPFYRENKQGWQNSIRHNLSLNECFVTVARDDRRPGKGSFWTLDPDSHGMFENGSFL 116

[Close]

BLAST of forkhead box A-1 vs. Ensembl Yeast
Match: HCM1 (Forkhead transcription factor; drives S-phase activation of genes involved in chromosome segregation, spindle dynamics, budding; also activates genes involved in respiration, use of alternative energy sources (like proline), NAD synthesis, oxidative stress resistance; key factor in early adaptation to nutrient deficiency and diauxic shift; suppressor of calmodulin mutants with specific SPB assembly defects; ortholog of C. elegans lifespan regulator PHA-4 [Source:SGD;Acc:S000000661])

HSP 1 Score: 98.2117 bits (243), Expect = 6.847e-22
Identity = 63/162 (38.89%), Postives = 88/162 (54.32%), Query Frame = 1

Query:  892 KPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTK-PNIK-QLDLSSDLLTNQGHNI 1371
            KPPYSY +LI +AI  S     TLS+IY +I  HFPYY+Q    WQNSIRH+LS ND F+K  +S +  GKG +W + P +   F  G   R  +  KD  ++IG+  +  +T       E+   N      +  E   K P+I+ QL+ S  L  +Q H+I
Sbjct:  109 KPPYSYATLICLAILQSQEGKLTLSQIYHWIHVHFPYYKQKDASWQNSIRHNLSLNDAFIKTEKSCD--GKGHFWEVRPGAETKFFKGEN-RGYEFVKDSLQDIGKYFEIDSTLDELEQVESGEGNDDLPDEEEREEAGKFPSIEIQLNSSPILRVSQLHHI 267

[Close]

BLAST of forkhead box A-1 vs. Ensembl Yeast
Match: FKH2 (Forkhead family transcription factor; rate-limiting activator of replication origins; evolutionarily conserved regulator of lifespan; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; positively regulates transcriptional elongation; facilitates clustering, activation of early-firing replication origins; negative role in chromatin silencing at HML and HMR; major role in expression of G2/M phase genes; relocalizes to cytosol under hypoxia [Source:SGD;Acc:S000005012])

HSP 1 Score: 89.7373 bits (221), Expect = 5.924e-19
Identity = 38/79 (48.10%), Postives = 55/79 (69.62%), Query Frame = 1

Query:  886 HAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTL 1122
            + KPP+SY ++IT AI +SP  + +L++IY++I  ++ YYR  +  WQNSIRH+LS N  F KV R P +PGKG  W +
Sbjct:  338 NVKPPHSYATMITQAILSSPEGVISLADIYKYISSNYAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRI 416

[Close]

BLAST of forkhead box A-1 vs. Ensembl Yeast
Match: FKH1 (Forkhead family transcription factor; rate-limiting replication origin activator; evolutionarily conserved lifespan regulator; binds multiple chromosomal elements with distinct specificities, cell cycle dynamics; regulates transcription elongation, chromatin silencing at mating loci, expression of G2/M phase genes; facilitates clustering, activation of early-firing replication origins; binds HML recombination enhancer, regulates donor preference during mating-type switching [Source:SGD;Acc:S000001393])

HSP 1 Score: 83.1889 bits (204), Expect = 2.846e-17
Identity = 42/112 (37.50%), Postives = 66/112 (58.93%), Query Frame = 1

Query:  841 NSISNNNRPYQRSYT--------HAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFEN 1152
            N+++N N P+  + +        + KPP SY S+IT AI ++P    +L++IY+FI D++ +YR +Q  WQNS+RH+LS N  F KV +   + GKG  W +  +    F N
Sbjct:  278 NAVTNGNVPHIENPSDLSLDENRYIKPPQSYASMITQAILSTPEGSISLADIYKFISDNYAFYRFSQMAWQNSVRHNLSLNKAFEKVPKRAGQQGKGMNWKISDEVRRDFLN 389

[Close]

BLAST of forkhead box A-1 vs. Ensembl Yeast
Match: FHL1 (Regulator of ribosomal protein (RP) transcription; has forkhead associated domain that binds phosphorylated proteins; recruits coactivator Ifh1p or corepressor Crf1p to RP gene promoters; also has forkhead DNA-binding domain though in vitro DNA binding assays give inconsistent results; computational analyses suggest it binds DNA directly at highly active RP genes and indirectly through Rap1p motifs at others; suppresses RNA pol III and splicing factor prp4 mutants [Source:SGD;Acc:S000006308])

HSP 1 Score: 67.3958 bits (163), Expect = 5.059e-12
Identity = 42/115 (36.52%), Postives = 57/115 (49.57%), Query Frame = 1

Query:  886 HAKPPYSYISLITMAIQN-SPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAA 1227
              KP  SY +++T  I+  S     +LSEIY  I + FPYY+     WQ+S+RH+LS N  F KVS    K GKG  W L  +         Y+  ++R K    EI     +AA
Sbjct:  459 RTKPTVSYSAMLTTCIRKYSTAKGMSLSEIYAGIRELFPYYKYCPDGWQSSVRHNLSLNKSFRKVS----KEGKGWLWGLDEE---------YIAERERQKKKQSEIAVAKAQAA 560

[Close]

BLAST of forkhead box A-1 vs. Ensembl Nematostella
Match: EDO42492 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1E3])

HSP 1 Score: 213.386 bits (542), Expect = 8.410e-64
Identity = 97/122 (79.51%), Postives = 104/122 (85.25%), Query Frame = 1

Query:  820 SDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            S +P +     +  + Y+RSYTHAKPPYSYISLITMAIQ SP  M TLSEIYQFIMD FPYYRQNQQRWQNSIRHSLSFNDCFVKV RSP++PGKGSYWTLHP  GNMFENGCYLRRQKRFK
Sbjct:   16 SQNPHELKKSKDKEKAYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQFIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVPRSPDRPGKGSYWTLHPDCGNMFENGCYLRRQKRFK 137

[Close]

BLAST of forkhead box A-1 vs. Ensembl Nematostella
Match: EDO39562 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9S5])

HSP 1 Score: 179.874 bits (455), Expect = 1.111e-51
Identity = 88/149 (59.06%), Postives = 104/149 (69.80%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDT 1308
            RP + SY  AKPPYSYISL  MAIQ+SP  M +LSEIYQFIMDHFP+YR N QRWQNS+RH+LSFNDCFVK+ R P++PGKGS W LHP  G MFENG +LRR+KRFK    E  R S+ A      + T  + D  S    ++A S T
Sbjct:    3 RPLRNSYGSAKPPYSYISLTAMAIQSSPQKMLSLSEIYQFIMDHFPFYRDNTQRWQNSLRHNLSFNDCFVKIPRRPDQPGKGSLWALHPDCGTMFENGSFLRRRKRFKS---ERERTSKLAKL---ISATREDEDELSPSEQESAPSPT 145

[Close]

BLAST of forkhead box A-1 vs. Ensembl Nematostella
Match: EDO39529 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9S2])

HSP 1 Score: 150.214 bits (378), Expect = 8.634e-43
Identity = 69/101 (68.32%), Postives = 83/101 (82.18%), Query Frame = 1

Query:  886 HAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSP-EKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
              KPP+SYI+LITM+I+ SP  M TL+EIY+FIM  FPY+R+NQQ+WQNSIRH+LS NDCFVKV RS   KPGKG+YWTLHP  G+MF +G +LRR KRFK
Sbjct:   14 EVKPPFSYIALITMSIEASPYRMRTLNEIYEFIMTRFPYFRKNQQKWQNSIRHNLSLNDCFVKVPRSIFGKPGKGNYWTLHPSCGDMFGSGSFLRRPKRFK 114

[Close]

BLAST of forkhead box A-1 vs. Ensembl Nematostella
Match: EDO33900 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SQU5])

HSP 1 Score: 144.05 bits (362), Expect = 6.086e-37
Identity = 72/116 (62.07%), Postives = 86/116 (74.14%), Query Frame = 1

Query:  892 KPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYL--RRQKRFKDPHREIGRQSQRAATG 1233
            KPPYSYI+LI MAIQ++P    TLS IY FIMD FPYYR N+Q WQNSIRH+LS N+CFVKV R  +KPGKGS+W L P S NMFENG YL  R++ R KD  + +  +SQR + G
Sbjct:   79 KPPYSYIALIAMAIQSAPEKRITLSGIYSFIMDRFPYYRNNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSFWMLDPDSLNMFENGSYLRRRKRFRKKDVQKSMEGESQRKSDG 194

[Close]

BLAST of forkhead box A-1 vs. Ensembl Nematostella
Match: EDO45105 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTX1])

HSP 1 Score: 123.25 bits (308), Expect = 2.076e-33
Identity = 57/89 (64.04%), Postives = 66/89 (74.16%), Query Frame = 1

Query:  889 AKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENG 1155
            +KPPYSYI+LITMAI  SP    TLS+I +FI   FPYYR+    WQNSIRH+LS NDCFVK+ R P  PGKG+YWTL P S  MF+NG
Sbjct:    2 SKPPYSYIALITMAILQSPQRKLTLSDICEFIKRRFPYYREKFPSWQNSIRHNLSLNDCFVKMPREPGNPGKGNYWTLDPASEGMFDNG 90

[Close]

BLAST of forkhead box A-1 vs. Ensembl Medaka
Match: ENSORLT00000024271.2 (forkhead box A1 [Source:NCBI gene;Acc:100301627])

HSP 1 Score: 217.238 bits (552), Expect = 2.723e-63
Identity = 98/128 (76.56%), Postives = 108/128 (84.38%), Query Frame = 1

Query:  850 SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATG 1233
            + +N+ ++RSY HAKPPYSYISLITMAIQ +P  M TLSEIYQ+IMD FPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSP+KPGKGSYWTLHP SGNMFENGCYLRRQKRFK   +  G+   R   G
Sbjct:  135 ARDNKTFRRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKKISGKADGRKEQG 262

[Close]

BLAST of forkhead box A-1 vs. Ensembl Medaka
Match: foxa2 (Me-HNF3b protein [Source:NCBI gene;Acc:100049256])

HSP 1 Score: 216.468 bits (550), Expect = 6.283e-63
Identity = 104/162 (64.20%), Postives = 120/162 (74.07%), Query Frame = 1

Query:  850 SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRF--------KDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTK 1311
            S + + Y+RSYTHAKPPYSYISLITMAIQ SP  M TL+EIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RSP+KPGKGS+WTLHP SGNMFENGCYLRRQKRF        K+P R+ G      ++    N  E+ H N+S      + SD K
Sbjct:  136 SRDPKTYRRSYTHAKPPYSYISLITMAIQQSPSKMLTLAEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKKMSMKEPGRKGGDGGSANSSSDSCNGNESPHSNSSSGEHKRSLSDMK 297

[Close]

BLAST of forkhead box A-1 vs. Ensembl Medaka
Match: foxa3 (forkhead box A3 [Source:NCBI gene;Acc:100049257])

HSP 1 Score: 215.312 bits (547), Expect = 3.960e-62
Identity = 107/154 (69.48%), Postives = 122/154 (79.22%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK--DPHREIGRQSQRAATGPGS----NVTENNHDNASQEASDNAESD 1305
            +PY+RS THAKPPYSYISLITMAIQ S   M TL+EIYQ+IMD FPYYR+NQQRWQNSIRHSLSFNDCFVKV+RSP+KPGKGSYWTLHPQSGNMFENGCYLRRQKRFK  D   + G ++Q   +G GS    ++ EN+      E  D+A SD
Sbjct:  140 KPYRRSLTHAKPPYSYISLITMAIQQSGSKMLTLNEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKIEDKASKKGSKNQEGGSGKGSHSGDHLVENHSPAGGSEGPDSAHSD 293

[Close]

BLAST of forkhead box A-1 vs. Ensembl Medaka
Match: ENSORLT00000045293.1 (forkhead box A [Source:NCBI gene;Acc:100301602])

HSP 1 Score: 204.142 bits (518), Expect = 3.428e-59
Identity = 94/126 (74.60%), Postives = 106/126 (84.13%), Query Frame = 1

Query:  850 SNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAA 1227
            +  ++PY+RSYTHAKPPYSYISLITMAIQ S   M TL+EIYQ+IMD FP+YRQNQQRWQNSIRHSLSFNDCF+KV RS +KPGKGS+W LHP SGNMFENGCYLRRQKRFK  +R  G   + AA
Sbjct:  102 TRESKPYRRSYTHAKPPYSYISLITMAIQQSDNKMLTLNEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFIKVPRSSDKPGKGSFWALHPDSGNMFENGCYLRRQKRFKCKNRSGGGDGEPAA 227

[Close]

BLAST of forkhead box A-1 vs. Ensembl Medaka
Match: foxb1 (forkhead box B1 [Source:NCBI gene;Acc:100301603])

HSP 1 Score: 174.481 bits (441), Expect = 1.317e-48
Identity = 73/108 (67.59%), Postives = 89/108 (82.41%), Query Frame = 1

Query:  862 RPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
            RP + +Y+  KPPYSYISL  MAIQ+ P  M  LSEIY+FIMD FPYYR+N QRWQNS+RH+LSFNDCF+K+ R P++PGKGS+W LHP  G+MFENG +LRR+KRFK
Sbjct:    3 RPGRNTYSDQKPPYSYISLTAMAIQSCPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPNCGDMFENGSFLRRRKRFK 110

[Close]

BLAST of forkhead box A-1 vs. Planmine SMEST
Match: SMESG000065670.1 (SMESG000065670.1)

HSP 1 Score: 905.975 bits (2340), Expect = 0.000e+0
Identity = 485/485 (100.00%), Postives = 485/485 (100.00%), Query Frame = 1

Query:  571 MLGKNPYETAMSNVYSLPPGGSIYNMNPMSISSAGYNSQQVSTLSLNLTGIGPHSLXXXXXXXXXXXXXXXXXRQGLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNIKQLDLSSDLLTNQGHNIKNTNPTSVSQSCSMFHRKKENCSPVEMKLXXXXXXXXXXEHPQIHYNPNQQFYSNQQNIFQQSSLDHYSLLASDDPLGQGMHLPPGANSVFGLYGAHNLPNDDQISVSLPSISLSGHPYDNLSTAMAYQYEASQHNSSLLTTSNPFSIDRLMHPRLVAAAMGVSPHDTLYAGATGPSVDLEHMKXXXXXXXXXXXXXAMSDYYKYVQNPQPGNSDMSL 2025
            MLGKNPYETAMSNVYSLPPGGSIYNMNPMSISSAGYNSQQVSTLSLNLTGIGPHSLSPMSASMSGIAAMAGGMRQGLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNIKQLDLSSDLLTNQGHNIKNTNPTSVSQSCSMFHRKKENCSPVEMKLNNQNQQSNQQEHPQIHYNPNQQFYSNQQNIFQQSSLDHYSLLASDDPLGQGMHLPPGANSVFGLYGAHNLPNDDQISVSLPSISLSGHPYDNLSTAMAYQYEASQHNSSLLTTSNPFSIDRLMHPRLVAAAMGVSPHDTLYAGATGPSVDLEHMKYYSNYNNVPPYSSAMSDYYKYVQNPQPGNSDMSL
Sbjct:    1 MLGKNPYETAMSNVYSLPPGGSIYNMNPMSISSAGYNSQQVSTLSLNLTGIGPHSLSPMSASMSGIAAMAGGMRQGLELGLGRSDSPRDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNIKQLDLSSDLLTNQGHNIKNTNPTSVSQSCSMFHRKKENCSPVEMKLNNQNQQSNQQEHPQIHYNPNQQFYSNQQNIFQQSSLDHYSLLASDDPLGQGMHLPPGANSVFGLYGAHNLPNDDQISVSLPSISLSGHPYDNLSTAMAYQYEASQHNSSLLTTSNPFSIDRLMHPRLVAAAMGVSPHDTLYAGATGPSVDLEHMKYYSNYNNVPPYSSAMSDYYKYVQNPQPGNSDMSL 485

[Close]

BLAST of forkhead box A-1 vs. Planmine SMEST
Match: SMESG000067799.1 (SMESG000067799.1)

HSP 1 Score: 202.216 bits (513), Expect = 1.382e-59
Identity = 90/115 (78.26%), Postives = 100/115 (86.96%), Query Frame = 1

Query:  889 AKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHRE----IGRQSQR 1221
            +KPPYSYISLITMAIQNSP  MCTLSEIYQFIMD FPYY+QNQQRWQNSIRHSLSFNDCF+K SR  EKPGKGS+W LHP SGNMFENGC+LRRQKRFKDP +     +G+ S++
Sbjct:   45 SKPPYSYISLITMAIQNSPQKMCTLSEIYQFIMDSFPYYQQNQQRWQNSIRHSLSFNDCFIKASRCTEKPGKGSFWVLHPDSGNMFENGCFLRRQKRFKDPRKHKLILLGKDSEK 159

[Close]

BLAST of forkhead box A-1 vs. Planmine SMEST
Match: SMESG000015673.1 (SMESG000015673.1)

HSP 1 Score: 159.073 bits (401), Expect = 5.035e-42
Identity = 67/99 (67.68%), Postives = 81/99 (81.82%), Query Frame = 1

Query:  889 AKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
             KPPYSYI+LITMA+   P    TLS IYQFIM+ FPYYR+N+Q WQNSIRH+LS N+CF+K+ R  +KPGKGSYW LHPQ+ NMFENG +LRR++RFK
Sbjct:   72 VKPPYSYIALITMAVHAHPEKKVTLSGIYQFIMEKFPYYRENKQGWQNSIRHNLSLNECFIKIPRDDKKPGKGSYWALHPQAYNMFENGSFLRRRRRFK 170

[Close]

BLAST of forkhead box A-1 vs. Planmine SMEST
Match: SMESG000004239.1 (SMESG000004239.1)

HSP 1 Score: 153.295 bits (386), Expect = 2.479e-40
Identity = 77/149 (51.68%), Postives = 103/149 (69.13%), Query Frame = 1

Query:  832 RDKNSISNNNRPYQRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQ 1278
             ++N+I   N+   RS    KPPYSYI+LITMAI + P +  TL+ IYQFI + FPYYR+N+Q WQNSIRH+LS N+CF+KVSR  ++ GKGSYWTLHP + NMFENG +LRR++RFK     I  +    AT   S++  +N D+  +
Sbjct:  128 ENQNNIKIENKNDNRSL--VKPPYSYIALITMAITSQPDHRITLNGIYQFISERFPYYRENKQGWQNSIRHNLSLNECFIKVSRGDQRSGKGSYWTLHPNAYNMFENGSFLRRRRRFKYKDDTISAE----ATATNSDIIISNSDDLEK 270

[Close]

BLAST of forkhead box A-1 vs. Planmine SMEST
Match: SMESG000077075.1 (SMESG000077075.1)

HSP 1 Score: 139.428 bits (350), Expect = 3.116e-35
Identity = 62/99 (62.63%), Postives = 75/99 (75.76%), Query Frame = 1

Query:  889 AKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQRWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRRQKRFK 1185
             KPPYSYI+LITMAI  SP    TLS I +FIM  FPYY+     WQNSIRH+LS NDCF+K+ R P  PGKG+YWTL P+S +MF+NG +LRR+KR+K
Sbjct:  150 VKPPYSYIALITMAILRSPQRKLTLSGICEFIMGRFPYYKDRFPAWQNSIRHNLSLNDCFIKIPREPGNPGKGNYWTLDPRSEDMFDNGSFLRRRKRYK 248

The following BLAST results are available for this feature:

BLAST of forkhead box A-1 vs. Ensembl Human
BLAST of forkhead box A-1 vs. Ensembl Celegans
BLAST of forkhead box A-1 vs. Ensembl Fly
BLAST of forkhead box A-1 vs. Ensembl Zebrafish
BLAST of forkhead box A-1 vs. Ensembl Xenopus
BLAST of forkhead box A-1 vs. Ensembl Mouse
BLAST of forkhead box A-1 vs. UniProt/SwissProt
BLAST of forkhead box A-1 vs. TrEMBL
BLAST of forkhead box A-1 vs. Ensembl Cavefish
BLAST of forkhead box A-1 vs. Ensembl Sea Lamprey
BLAST of forkhead box A-1 vs. Ensembl Yeast
BLAST of forkhead box A-1 vs. Ensembl Nematostella
BLAST of forkhead box A-1 vs. Ensembl Medaka
BLAST of forkhead box A-1 vs. Planmine SMEST

BLAST of forkhead box A-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
FOXA1	1.464e-61	79.66	forkhead box A1 [Source:HGNC Symbol;Acc:HGNC:5021]	[more]
FOXA2	2.573e-60	75.78	forkhead box A2 [Source:HGNC Symbol;Acc:HGNC:5022]	[more]
FOXA2	2.737e-60	75.78	forkhead box A2 [Source:HGNC Symbol;Acc:HGNC:5022]	[more]
FOXA3	9.884e-59	76.86	forkhead box A3 [Source:HGNC Symbol;Acc:HGNC:5023]	[more]
FOXB1	5.421e-49	68.52	forkhead box B1 [Source:HGNC Symbol;Acc:HGNC:3799]	[more]

BLAST of forkhead box A-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
pha-4	1.588e-53	62.94	Defective pharyngeal development protein 4 [Sourc...	[more]
pha-4	1.667e-53	62.94	Defective pharyngeal development protein 4 [Sourc...	[more]
pha-4	2.779e-53	62.94	Defective pharyngeal development protein 4 [Sourc...	[more]
lin-31	4.137e-38	61.39	pep chromosome:WBcel235:II:3982549:3986944:1 gene:...	[more]
unc-130	7.480e-38	60.58	pep chromosome:WBcel235:II:11281986:11283953:1 gen...	[more]

BLAST of forkhead box A-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fkh	7.385e-65	67.30	gene:FBgn0000659 transcript:FBtr0300259	[more]
fkh	7.385e-65	67.30	gene:FBgn0000659 transcript:FBtr0345227	[more]
fkh	7.385e-65	67.30	gene:FBgn0000659 transcript:FBtr0085321	[more]
fkh	9.634e-65	67.30	gene:FBgn0000659 transcript:FBtr0346765	[more]
fkh	1.498e-63	67.30	gene:FBgn0000659 transcript:FBtr0330333	[more]

BLAST of forkhead box A-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
foxa1	2.437e-64	73.05	forkhead box A1 [Source:ZFIN;Acc:ZDB-GENE-990415-7...	[more]
foxa2	1.758e-61	56.99	forkhead box A2 [Source:NCBI gene;Acc:30126]	[more]
foxa3	1.347e-60	57.29	forkhead box A3 [Source:ZFIN;Acc:ZDB-GENE-980526-4...	[more]
foxa	1.873e-53	78.30	forkhead box A sequence [Source:ZFIN;Acc:ZDB-GENE-...	[more]
foxa	2.366e-53	78.30	forkhead box A sequence [Source:ZFIN;Acc:ZDB-GENE-...	[more]

BLAST of forkhead box A-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
xk	9.361e-63	73.88	X-linked Kx blood group [Source:Xenbase;Acc:XB-GEN...	[more]
foxa2	5.573e-61	83.93	forkhead box A2 [Source:NCBI gene;Acc:395063]	[more]
ventx1.2	1.150e-60	77.69	VENT homeobox 1, gene 2 [Source:Xenbase;Acc:XB-GEN...	[more]
serpinc1	1.686e-47	67.59	serpin peptidase inhibitor, clade C (antithrombin)...	[more]
FOXB2	2.618e-42	66.34	forkhead box B2 [Source:NCBI gene;Acc:101730239]	[more]

BLAST of forkhead box A-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Foxa2	2.087e-63	60.45	forkhead box A2 [Source:MGI Symbol;Acc:MGI:1347476...	[more]
Foxa2	2.623e-63	60.45	forkhead box A2 [Source:MGI Symbol;Acc:MGI:1347476...	[more]
Foxa1	1.389e-61	79.66	forkhead box A1 [Source:MGI Symbol;Acc:MGI:1347472...	[more]
Foxa3	6.126e-59	84.91	forkhead box A3 [Source:MGI Symbol;Acc:MGI:1347477...	[more]
Foxb1	4.033e-49	68.52	forkhead box B1 [Source:MGI Symbol;Acc:MGI:1927549...	[more]

BLAST of forkhead box A-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q17241\|SGF1_BOMMO	5.000e-66	76.69	Silk gland factor 1 OS=Bombyx mori OX=7091 GN=SGF1...	[more]
sp\|P14734\|FKH_DROME	7.402e-64	67.30	Protein fork head OS=Drosophila melanogaster OX=72...	[more]
sp\|P35583\|FOXA2_MOUSE	1.460e-62	60.45	Hepatocyte nuclear factor 3-beta OS=Mus musculus O...	[more]
sp\|O42097\|FOXA2_ORYLA	5.632e-62	64.20	Hepatocyte nuclear factor 3-beta OS=Oryzias latipe...	[more]
sp\|P32315\|FXA1B_XENLA	2.881e-61	71.74	Forkhead box protein A1-B OS=Xenopus laevis OX=835...	[more]

BLAST of forkhead box A-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZIE5	0.000e+0	100.00	Forkhead box A-1 OS=Schmidtea mediterranea OX=7932...	[more]
Q9NDK9	0.000e+0	92.39	Winged helix/forkhead transcription factor DjFoxA ...	[more]
D3J1K2	8.534e-129	99.45	FoxA (Fragment) OS=Schmidtea polychroa OX=50054 GN...	[more]
A0A1B6CCN2	1.550e-66	60.54	Fork-head domain-containing protein OS=Clastoptera...	[more]
A0A224XIG3	5.234e-66	71.53	Putative forkhead/hnf-3-related transcription fact...	[more]

BLAST of forkhead box A-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
foxa1	2.668e-63	85.71	forkhead box A1 [Source:ZFIN;Acc:ZDB-GENE-990415-7...	[more]
foxa3	1.890e-62	53.11	hepatocyte nuclear factor 3-gamma [Source:NCBI gen...	[more]
foxa2	1.286e-59	64.05	forkhead box A2 [Source:NCBI gene;Acc:103033433]	[more]
foxa	3.586e-52	76.42	hepatocyte nuclear factor 3-gamma-like [Source:NCB...	[more]
foxb1a	8.014e-49	67.59	forkhead box B1 [Source:NCBI gene;Acc:103044512]	[more]

BLAST of forkhead box A-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
foxa2	2.590e-58	65.54	forkhead box A2 [Source:NCBI gene;Acc:30126]	[more]
ENSPMAT00000005206.1	7.710e-58	74.38	pep scaffold:Pmarinus_7.0:GL479371:8768:18483:1 ge...	[more]
foxb2	1.621e-47	66.67	forkhead box B2 [Source:ZFIN;Acc:ZDB-GENE-081104-3...	[more]
FOXC2	2.198e-41	66.34	forkhead box C2 [Source:HGNC Symbol;Acc:HGNC:3801]	[more]
ENSPMAT00000002547.1	2.405e-37	65.22	pep scaffold:Pmarinus_7.0:GL485262:1354:7435:1 gen...	[more]

BLAST of forkhead box A-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4


Match Name	E-value	Identity	Description
HCM1	6.847e-22	38.89	Forkhead transcription factor; drives S-phase acti...	[more]
FKH2	5.924e-19	48.10	Forkhead family transcription factor; rate-limitin...	[more]
FKH1	2.846e-17	37.50	Forkhead family transcription factor; rate-limitin...	[more]
FHL1	5.059e-12	36.52	Regulator of ribosomal protein (RP) transcription;...	[more]

BLAST of forkhead box A-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO42492	8.410e-64	79.51	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39562	1.111e-51	59.06	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO39529	8.634e-43	68.32	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33900	6.086e-37	62.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45105	2.076e-33	64.04	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of forkhead box A-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000024271.2	2.723e-63	76.56	forkhead box A1 [Source:NCBI gene;Acc:100301627]	[more]
foxa2	6.283e-63	64.20	Me-HNF3b protein [Source:NCBI gene;Acc:100049256]	[more]
foxa3	3.960e-62	69.48	forkhead box A3 [Source:NCBI gene;Acc:100049257]	[more]
ENSORLT00000045293.1	3.428e-59	74.60	forkhead box A [Source:NCBI gene;Acc:100301602]	[more]
foxb1	1.317e-48	67.59	forkhead box B1 [Source:NCBI gene;Acc:100301603]	[more]

BLAST of forkhead box A-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000065670.1	0.000e+0	100.00	SMESG000065670.1	[more]
SMESG000067799.1	1.382e-59	78.26	SMESG000067799.1	[more]
SMESG000015673.1	5.035e-42	67.68	SMESG000015673.1	[more]
SMESG000004239.1	2.479e-40	51.68	SMESG000004239.1	[more]
SMESG000077075.1	3.116e-35	62.63	SMESG000077075.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30027428
GenBank	AFJ24799.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30027428 ID=SMED30027428|Name=forkhead box A-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2149bp
ATCACTTGGTGCTGCTTTTTGCCCCGATAAATCTCTCGGTGCTCCAAAAT
TTGTGTAAGCGAGCAAAAGATGATTGGGCAATTTCTAGCACGTCATTCGG
CAACGATGTTTACAAGTTTCTCTGATTGGATGATAAAGTAGAAACTTTCC
GAAAATGAAACTTCTCCGAACATGCGCATACCGACTGAAAATTAACTCTA
AGCCAGCCAATGGAATTGAAGCAAAATTCAAGAGAATATTAATTGACTTC
GCGAATGAACTCAAATTTTCTATTGGCGTATTGTGTGTGCCTCATTGTGA
GTGGTTGCGATCGCATCTCAAATTATTTACACACAAAAAAATAACGCACA
CAGACATTGAATAGATATATTTGATCAAGTCAATATCACAATGTCAATAT
TAGCTTTTTCTGAAGAAAGAAGACGAACTAGAAGAAAAACAACAACGAAA
TAGATTCGATAAGGCTACTGAGCGATTTTCATAATCTAAATATTATTTTA
TTATTGATACGGACAAAAATTGGTCTTTTACCAAGTACTACTAGATTGTT
GATAAAGAGAGGTTATTTAGATGCTTGGAAAAAATCCTTATGAAACTGCA
ATGAGCAACGTGTATTCTCTACCTCCGGGAGGTTCTATTTACAATATGAA
CCCGATGAGTATATCATCAGCTGGCTACAACTCTCAACAAGTATCAACAC
TATCGTTGAACTTGACCGGAATCGGACCTCATTCATTAAGCCCAATGAGT
GCAAGCATGTCGGGTATAGCTGCAATGGCCGGTGGAATGAGACAAGGTCT
TGAGTTGGGTCTTGGTAGAAGTGATAGTCCAAGAGATAAAAATTCAATTT
CCAATAACAACCGACCATATCAAAGAAGTTACACTCATGCCAAGCCTCCA
TACAGTTATATAAGTTTGATAACAATGGCGATTCAAAATTCTCCAGTAAA
CATGTGCACTCTATCGGAGATCTATCAATTCATTATGGATCATTTTCCAT
ACTATCGTCAAAATCAACAGCGATGGCAGAATTCGATTCGACATTCTTTG
TCCTTCAACGATTGCTTTGTTAAGGTTAGTAGAAGCCCAGAAAAACCAGG
TAAAGGCTCATATTGGACCTTGCATCCTCAATCAGGTAACATGTTTGAAA
ACGGTTGTTATCTCAGAAGACAAAAGCGATTCAAAGATCCACACAGAGAA
ATCGGCAGACAGAGTCAAAGAGCTGCCACTGGTCCTGGATCAAATGTCAC
AGAAAACAATCACGACAACGCATCGCAAGAAGCTAGTGATAACGCAGAAA
GTGATACGAAACCCAACATCAAGCAACTTGATTTATCAAGCGATCTCTTA
ACTAATCAAGGTCATAATATTAAAAATACTAATCCAACTTCTGTTAGTCA
GAGTTGTTCGATGTTTCATCGGAAAAAGGAAAACTGCTCACCAGTAGAAA
TGAAATTGAATAACCAAAACCAACAATCAAACCAGCAAGAACATCCACAA
ATCCATTACAATCCCAATCAGCAATTCTACTCAAATCAGCAAAACATTTT
CCAACAAAGTTCTCTTGATCATTACAGTCTATTAGCATCCGATGATCCTC
TTGGTCAAGGTATGCACTTGCCACCAGGTGCAAATAGTGTTTTCGGACTT
TACGGGGCACATAACTTACCAAACGATGATCAAATTTCAGTGTCATTACC
ATCGATATCCTTATCCGGACATCCGTATGACAATTTATCAACAGCAATGG
CATATCAATATGAAGCATCTCAACACAATTCTTCATTACTAACGACAAGT
AATCCGTTCTCAATAGATCGTTTGATGCATCCAAGACTAGTCGCTGCAGC
GATGGGGGTCAGTCCCCATGATACTCTATACGCAGGAGCTACCGGCCCAT
CAGTTGATCTAGAACACATGAAATACTACTCAAACTACAACAATGTGCCT
CCTTATTCCTCTGCAATGTCTGACTACTACAAATATGTACAAAATCCTCA
GCCGGGCAACAGCGACATGAGTCTTTGAATTGAGTCCATTGAAGTCTACG
GCAGTTTCCTCGAAATTTCACATTCAACCAGATGTTTATCGCCTAATATA
AAGCTGTGTTTTTTTATTTATTTACAATTAAATCTTTGTACAAGAGATC

protein sequence of SMED30027428-orf-1

>SMED30027428-orf-1 ID=SMED30027428-orf-1|Name=SMED30027428-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=486bp
MLGKNPYETAMSNVYSLPPGGSIYNMNPMSISSAGYNSQQVSTLSLNLTG
IGPHSLSPMSASMSGIAAMAGGMRQGLELGLGRSDSPRDKNSISNNNRPY
QRSYTHAKPPYSYISLITMAIQNSPVNMCTLSEIYQFIMDHFPYYRQNQQ
RWQNSIRHSLSFNDCFVKVSRSPEKPGKGSYWTLHPQSGNMFENGCYLRR
QKRFKDPHREIGRQSQRAATGPGSNVTENNHDNASQEASDNAESDTKPNI
KQLDLSSDLLTNQGHNIKNTNPTSVSQSCSMFHRKKENCSPVEMKLNNQN
QQSNQQEHPQIHYNPNQQFYSNQQNIFQQSSLDHYSLLASDDPLGQGMHL
PPGANSVFGLYGAHNLPNDDQISVSLPSISLSGHPYDNLSTAMAYQYEAS
QHNSSLLTTSNPFSIDRLMHPRLVAAAMGVSPHDTLYAGATGPSVDLEHM
KYYSNYNNVPPYSSAMSDYYKYVQNPQPGNSDMSL*

Aliases

The feature 'forkhead box A-1' has the following synonyms


Synonym
foxA1

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0000420	parapharyngeal region
PLANA:0000465	pharynx nerve plexus
PLANA:0000478	pharynx musculature
PLANA:0002142	parenchyma
PLANA:0004528	pharynx epithelium
PLANA:0000049	digestive system
PLANA:0000058	embryonic digestive system
PLANA:0000110	pharynx progenitor cell
PLANA:0000016	pharynx
PLANA:0000023	embryonic pharynx

Vocabulary: **INTERPRO**
Term	Definition
IPR036388	WH-like_DNA-bd_sf
IPR036390	WH_DNA-bd_sf
IPR001766	Fork_head_dom
IPR011991	WHTH_DNA-bd_dom
IPR013638	Fork-head_N
IPR018122	TF_fork_head_CS_1
IPR030456	TF_fork_head_CS_2

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated

Vocabulary: **molecular function**
Term	Definition
GO:0003700	transcription factor activity, sequence-specific DNA binding
GO:0043565	sequence-specific DNA binding
GO:0019904	protein domain specific binding
GO:0008134	transcription factor binding
GO:0003677	DNA binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

Vocabulary: **Schmidtea mediterranea Developmental Stages**
Term	Definition
PLANA:0000003	Stage 3
PLANA:0000005	Stage 5
PLANA:0000006	Stage 6
PLANA:0000004	Stage 4
PLANA:0000007	Stage 7
PLANA:0000008	Stage 8

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001766	Fork head domain	PRINTS	PR00053	FORKHEAD	coord: 108..121 score: 78.17 coord: 152..169 score: 78.22 coord: 129..146 score: 60.98
IPR001766	Fork head domain	SMART	SM00339	forkneu4	coord: 106..196 e-value: 2.6E-58 score: 209.7
IPR001766	Fork head domain	PFAM	PF00250	Forkhead	coord: 108..193 e-value: 8.7E-38 score: 128.5
IPR001766	Fork head domain	PROSITE	PS50039	FORK_HEAD_3	coord: 108..202 score: 38.52
IPR001766	Fork head domain	CDD	cd00059	FH	coord: 108..185 e-value: 1.7863E-47 score: 156.56
IPR013638	Fork-head N-terminal	PFAM	PF08430	Forkhead_N	coord: 7..107 e-value: 1.4E-6 score: 29.0
IPR036388	Winged helix-like DNA-binding domain superfamily	GENE3D	G3DSA:1.10.10.10		coord: 106..206 e-value: 2.1E-46 score: 158.1
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 206..248
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 81..101
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 217..248
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 87..101
None	No IPR available	PANTHER	PTHR11829	FORKHEAD BOX PROTEIN	coord: 20..478
None	No IPR available	PANTHER	PTHR11829:SF353	PROTEIN FORK HEAD	coord: 20..478
IPR018122	Fork head domain conserved site1	PROSITE	PS00657	FORK_HEAD_1	coord: 108..121
IPR030456	Fork head domain conserved site 2	PROSITE	PS00658	FORK_HEAD_2	coord: 152..158
IPR036390	Winged helix DNA-binding domain superfamily	SUPERFAMILY	SSF46785	"Winged helix" DNA-binding domain	coord: 107..202