Ubiquitin-conjugating enzyme E2 S

Overview
NameUbiquitin-conjugating enzyme E2 S
Smed IDSMED30027390
Length (bp)883
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ubiquitin-conjugating enzyme E2 S (SMED30027390) t-SNE clustered cells

Violin plots show distribution of expression levels for Ubiquitin-conjugating enzyme E2 S (SMED30027390) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ubiquitin-conjugating enzyme E2 S (SMED30027390) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ubiquitin-conjugating enzyme E2 S (SMED30027390) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027390

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
posterior sideSMED30027390h1SMcG0003628 dd_Smed_v4_7621_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30027390h1SMcG0003628 dd_Smed_v4_7621_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Human
Match: UBE2S (ubiquitin conjugating enzyme E2 S [Source:HGNC Symbol;Acc:HGNC:17895])

HSP 1 Score: 193.356 bits (490), Expect = 1.348e-60
Identity = 84/153 (54.90%), Postives = 114/153 (74.51%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            +ENL PH+I+ + +E+  L  +P +GI +  NE ++TD+Q  I+GP  TPY  G FR+++ L   +P   PKG+F+TKIFHPN+   NGEICVN LK+DW+A+ GI+ + LT+KCLLI+PN ESALNEEAG+LLLE+Y EYA RARL T I+ 
Sbjct:    5 VENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFLTKIFHPNVG-ANGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYAARARLLTEIHG 156
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Human
Match: UBE2S (ubiquitin conjugating enzyme E2 S [Source:HGNC Symbol;Acc:HGNC:17895])

HSP 1 Score: 176.792 bits (447), Expect = 2.504e-54
Identity = 84/182 (46.15%), Postives = 114/182 (62.64%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFL-----------------------------TVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            +ENL PH+I+ + +E+  L  +P +GI +  NE ++TD+Q  I+GP  TPY  G FR+++ L   +P   PKG+F+TKIFHPN+   NGEICVN LK+DW+A+ GI+ + L                             T+KCLLI+PN ESALNEEAG+LLLE+Y EYA RARL T I+ 
Sbjct:    5 VENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFLTKIFHPNVG-ANGEICVNVLKRDWTAELGIRHVLLLSWKDKQCQTQDTQVLLRSAQEHLTMQRVTIKCLLIHPNPESALNEEAGRLLLENYEEYAARARLLTEIHG 185
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Human
Match: UBE2N (ubiquitin conjugating enzyme E2 N [Source:HGNC Symbol;Acc:HGNC:12492])

HSP 1 Score: 100.523 bits (249), Expect = 1.739e-25
Identity = 48/147 (32.65%), Postives = 81/147 (55.10%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            ++I +E ++L+  P+ GI    +E        +I GP ++P+E G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + AR +T +YA  N
Sbjct:    6 RRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNN 151
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Human
Match: UBE2B (ubiquitin conjugating enzyme E2 B [Source:HGNC Symbol;Acc:HGNC:12473])

HSP 1 Score: 96.6709 bits (239), Expect = 5.277e-24
Identity = 45/136 (33.09%), Postives = 78/136 (57.35%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRA 489
            +++ ++ ++L  +P  G++   +E  I    A+I GP  TP+E+G F++ +  S  YP + P   F++K+FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N +A QL  E+  EY KR 
Sbjct:    7 RRLMRDFKRLQEDPPVGVSGAPSENNIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVY-ADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRV 141
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Human
Match: UBE2A (ubiquitin conjugating enzyme E2 A [Source:HGNC Symbol;Acc:HGNC:12472])

HSP 1 Score: 95.5153 bits (236), Expect = 1.182e-23
Identity = 44/135 (32.59%), Postives = 78/135 (57.78%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKR 486
            +++ ++ ++L  +P  G++   +E  I    A+I GP  TP+E+G F++ +  +  YP + P   F++K+FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N +A QL  E+  EY KR
Sbjct:    7 RRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVY-ADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKR 140
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Celegans
Match: ubc-13 (Ubiquitin-conjugating enzyme E2 13 [Source:UniProtKB/Swiss-Prot;Acc:Q95XX0])

HSP 1 Score: 97.4413 bits (241), Expect = 9.610e-25
Identity = 49/144 (34.03%), Postives = 80/144 (55.56%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            ++I +E ++L+ +P+ GI+   +E        +I GP ++P+  G F++ + L   YP  APK  F+TKI+HPNI  K G IC++ LK  WS    I+ + L+++ LL  PN E  L  +  +    +  E  K A+ +T  YA
Sbjct:    7 RRIIKETQRLLADPVPGISANPDESNARYFHVMIAGPDDSPFAGGVFKLELFLPEEYPMAAPKVRFMTKIYHPNID-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPEDPLATDVAEQWKTNEAEAIKTAKQWTMNYA 149
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Celegans
Match: ubc-1 (Ubiquitin-conjugating enzyme E2 1 [Source:UniProtKB/Swiss-Prot;Acc:P52478])

HSP 1 Score: 98.2117 bits (243), Expect = 1.157e-24
Identity = 47/137 (34.31%), Postives = 79/137 (57.66%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRAR 492
            +++ ++ ++L  +P  G++    E  I   +AII GP ETP+E+G F++ +  +  YP + P   FI+K+FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N  A QL  E+  EY KR +
Sbjct:    7 RRLMRDFKKLQEDPPAGVSGAPTEDNILTWEAIIFGPQETPFEDGTFKLSLEFTEEYPNKPPTVKFISKMFHPNVY-ADGSICLDILQNRWSPTYDVAAILTSIQSLLDEPNPNSPANSLAAQLYQENRREYEKRVQ 142
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Celegans
Match: let-70 (Ubiquitin-conjugating enzyme E2 2 [Source:UniProtKB/Swiss-Prot;Acc:P35129])

HSP 1 Score: 91.2781 bits (225), Expect = 1.427e-22
Identity = 49/146 (33.56%), Postives = 77/146 (52.74%), Query Frame = 1 
Query:   76 VIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
             +K+I +E++ L  +P    +      ++   QA I GP E+PY+ G F + +     YP + PK  F T+I+HPNI+  NG IC++ L+  WS    I K+ L++  LL  PN +  L  E  ++   D   Y + AR +T  YA
Sbjct:    2 ALKRIQKELQDLGRDPPAQCSAGPVGDDLFHWQATIMGPPESPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNIN-SNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRERYNQLAREWTQKYA 146
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Celegans
Match: ubc-21 (Probable ubiquitin-conjugating enzyme E2 21 [Source:UniProtKB/Swiss-Prot;Acc:P52484])

HSP 1 Score: 92.8189 bits (229), Expect = 2.567e-22
Identity = 41/128 (32.03%), Postives = 69/128 (53.91%), Query Frame = 1 
Query:  130 GITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            GI +   E  + DI+  I GP  TPY  G F I++ +   YP + PK  F+T+I+HPNIS + G IC++ LK  W+A   ++ + L+++ +L  P      +    +  + +Y  +   A  +TS +A
Sbjct:   40 GIHVEIKENNLMDIKGFIKGPEGTPYAGGTFEIKVDIPEHYPFEPPKAKFVTRIWHPNISSQTGTICLDILKDKWTASLTLRTVLLSLQAMLCSPEPSDPQDAVVAKQFINNYPMFTATAVYWTSYFA 167
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Celegans
Match: ubc-8 (UBiquitin Conjugating enzyme [Source:UniProtKB/TrEMBL;Acc:Q9N2W9])

HSP 1 Score: 91.6633 bits (226), Expect = 7.206e-22
Identity = 43/113 (38.05%), Postives = 69/113 (61.06%), Query Frame = 1 
Query:  187 GPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLT-VKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            GP +T YENG +RIR+ + + YP ++P   F+ KIFHPNI   +G +C++ + + W+A + +  IF T +  LL YPNA   LN EA +L +    EY +  R +   +A+++
Sbjct:   41 GPKDTAYENGVWRIRVDMPDKYPFKSPSIGFLNKIFHPNIDEASGTVCLDVINQAWTALYDLTNIFDTFLPQLLTYPNAADPLNGEAARLYIHKPEEYRRTCREYVMRFASEH 153
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Fly
Match: CG8188 (gene:FBgn0030863 transcript:FBtr0346186)

HSP 1 Score: 197.208 bits (500), Expect = 1.398e-62
Identity = 90/169 (53.25%), Postives = 122/169 (72.19%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSD 561
            +ENL P  I+++ +E++++   P EGI +L NE ++TDIQA+IDGP  TPY  G FR+++ L+  +P   PK +F+TKIFHPN++  NGEICVNTLKKDW  D GIK I LT+KCLLI PN ESALNEEAG++LLE Y +Y++RAR+ T I+A      V + G+   D
Sbjct:    8 VENLSPQTIRQVMRELQEMETTPPEGIKVLINESDVTDIQALIDGPAGTPYAAGIFRVKLTLNKDFPLTPPKAYFLTKIFHPNVA-ANGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEAGKMLLERYDDYSQRARMMTEIHAQPAKCGVGAVGDAKDD 175
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Fly
Match: CG8188 (gene:FBgn0030863 transcript:FBtr0100463)

HSP 1 Score: 197.208 bits (500), Expect = 1.398e-62
Identity = 90/169 (53.25%), Postives = 122/169 (72.19%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSD 561
            +ENL P  I+++ +E++++   P EGI +L NE ++TDIQA+IDGP  TPY  G FR+++ L+  +P   PK +F+TKIFHPN++  NGEICVNTLKKDW  D GIK I LT+KCLLI PN ESALNEEAG++LLE Y +Y++RAR+ T I+A      V + G+   D
Sbjct:    8 VENLSPQTIRQVMRELQEMETTPPEGIKVLINESDVTDIQALIDGPAGTPYAAGIFRVKLTLNKDFPLTPPKAYFLTKIFHPNVA-ANGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEAGKMLLERYDDYSQRARMMTEIHAQPAKCGVGAVGDAKDD 175
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Fly
Match: CG8188 (gene:FBgn0030863 transcript:FBtr0074476)

HSP 1 Score: 197.208 bits (500), Expect = 1.398e-62
Identity = 90/169 (53.25%), Postives = 122/169 (72.19%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSD 561
            +ENL P  I+++ +E++++   P EGI +L NE ++TDIQA+IDGP  TPY  G FR+++ L+  +P   PK +F+TKIFHPN++  NGEICVNTLKKDW  D GIK I LT+KCLLI PN ESALNEEAG++LLE Y +Y++RAR+ T I+A      V + G+   D
Sbjct:    8 VENLSPQTIRQVMRELQEMETTPPEGIKVLINESDVTDIQALIDGPAGTPYAAGIFRVKLTLNKDFPLTPPKAYFLTKIFHPNVA-ANGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEAGKMLLERYDDYSQRARMMTEIHAQPAKCGVGAVGDAKDD 175
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Fly
Match: CG8188 (gene:FBgn0030863 transcript:FBtr0340633)

HSP 1 Score: 197.208 bits (500), Expect = 1.398e-62
Identity = 90/169 (53.25%), Postives = 122/169 (72.19%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSD 561
            +ENL P  I+++ +E++++   P EGI +L NE ++TDIQA+IDGP  TPY  G FR+++ L+  +P   PK +F+TKIFHPN++  NGEICVNTLKKDW  D GIK I LT+KCLLI PN ESALNEEAG++LLE Y +Y++RAR+ T I+A      V + G+   D
Sbjct:    8 VENLSPQTIRQVMRELQEMETTPPEGIKVLINESDVTDIQALIDGPAGTPYAAGIFRVKLTLNKDFPLTPPKAYFLTKIFHPNVA-ANGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEAGKMLLERYDDYSQRARMMTEIHAQPAKCGVGAVGDAKDD 175
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Fly
Match: ben (gene:FBgn0000173 transcript:FBtr0307296)

HSP 1 Score: 105.531 bits (262), Expect = 9.483e-28
Identity = 51/147 (34.69%), Postives = 83/147 (56.46%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            ++I +E ++L+  P+ GI  + +E        I+ GP ++P+E G F++ + L   YP  APK  FITKI+HPNI  + G IC++ LK  WS    I+ I L+++ LL  PN +  L  +  +L   +  E  + AR +T  YA ++
Sbjct:    6 RRIIKETQRLMQEPVPGINAIPDENNARYFHVIVTGPNDSPFEGGVFKLELFLPEDYPMSAPKVRFITKIYHPNID-RLGRICLDVLKDKWSPALQIRTILLSIQALLSAPNPDDPLANDVAELWKVNEAEAIRNAREWTQKYAVED 151
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Zebrafish
Match: ube2s (ubiquitin-conjugating enzyme E2S [Source:NCBI gene;Acc:565498])

HSP 1 Score: 184.882 bits (468), Expect = 1.609e-57
Identity = 82/153 (53.59%), Postives = 111/153 (72.55%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            +ENL P V++ + +E+  L  +P EGI +  +E +IT++   I+GP  TPY  G FR+R+ L   +P   P+G+F+TKIFHPN+  K GEICVN LK+DW A+ G++ + LT+KCLLI+PN ESALNEEAG+LLLEDY EYA RA L T I+A
Sbjct:    5 VENLPPQVLRLVYKEVSALAADPPEGIKIYPSEEDITELHTSIEGPEGTPYAGGVFRMRLVLGKDFPAVPPRGYFLTKIFHPNVGHK-GEICVNVLKRDWKAELGLRHVLLTIKCLLIHPNPESALNEEAGKLLLEDYKEYASRAHLLTEIHA 156
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Zebrafish
Match: ube2s (ubiquitin-conjugating enzyme E2S [Source:NCBI gene;Acc:565498])

HSP 1 Score: 184.882 bits (468), Expect = 1.683e-57
Identity = 82/153 (53.59%), Postives = 111/153 (72.55%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            +ENL P V++ + +E+  L  +P EGI +  +E +IT++   I+GP  TPY  G FR+R+ L   +P   P+G+F+TKIFHPN+  K GEICVN LK+DW A+ G++ + LT+KCLLI+PN ESALNEEAG+LLLEDY EYA RA L T I+A
Sbjct:    4 VENLPPQVLRLVYKEVSALAADPPEGIKIYPSEEDITELHTSIEGPEGTPYAGGVFRMRLVLGKDFPAVPPRGYFLTKIFHPNVGHK-GEICVNVLKRDWKAELGLRHVLLTIKCLLIHPNPESALNEEAGKLLLEDYKEYASRAHLLTEIHA 155
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Zebrafish
Match: ube2nb (ubiquitin-conjugating enzyme E2Nb [Source:ZFIN;Acc:ZDB-GENE-040426-1291])

HSP 1 Score: 99.7525 bits (247), Expect = 2.060e-25
Identity = 48/147 (32.65%), Postives = 81/147 (55.10%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            ++I +E ++L+  P+ GI    +E        +I GP ++P+E G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + AR +T +YA  N
Sbjct:    6 RRIIKETQRLLAEPVPGIKAEPDEGNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKSNEAQAIETARTWTRLYAGNN 151
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Zebrafish
Match: ube2na (ubiquitin-conjugating enzyme E2Na [Source:ZFIN;Acc:ZDB-GENE-040426-2873])

HSP 1 Score: 99.3673 bits (246), Expect = 3.447e-25
Identity = 48/147 (32.65%), Postives = 81/147 (55.10%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            ++I +E ++L+  P+ GI    +E        +I GP ++P+E G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + AR +T +YA  N
Sbjct:    6 RRIIKETQRLLAEPVPGIKAEPDEGNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARTWTRLYAGNN 151
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Zebrafish
Match: CR753897.1 (pep chromosome:GRCz11:CHR_ALT_CTG18_2_4:15781720:15792426:1 gene:ENSDARG00000111297.1 transcript:ENSDART00000193676.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR753897.1)

HSP 1 Score: 99.3673 bits (246), Expect = 3.505e-25
Identity = 50/151 (33.11%), Postives = 81/151 (53.64%), Query Frame = 1 
Query:   70 PHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            P  I K+  E ++L+  P+ GI    +E        +I GP ++P+E G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + AR +T +YA  N
Sbjct:    5 PLRIIKLFSETQRLLAEPVPGIKAEPDEGNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARTWTRLYAGNN 154
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Xenopus
Match: ube2s (ubiquitin conjugating enzyme E2 S [Source:NCBI gene;Acc:549192])

HSP 1 Score: 199.134 bits (505), Expect = 5.130e-63
Identity = 89/153 (58.17%), Postives = 117/153 (76.47%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            +ENL PH+I+++ +E+  L  +P EGI ++ NE +ITD+Q  I+GP  TPY  G FR+++ L   +P   PKG+F+TKIFHPN+S  NGEICVN LKKDW A+ GI+ + LT+KCLLI+PN ESALNEEAG+LLLE+Y EYA RARL T I+A
Sbjct:    5 VENLPPHIIRQVYKEVSTLTSDPPEGIKIIPNEEDITDVQVNIEGPEGTPYAGGIFRMKLILGKDFPAAPPKGYFLTKIFHPNVS-TNGEICVNVLKKDWKAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYASRARLMTEIHA 156
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Xenopus
Match: ube2n (ubiquitin conjugating enzyme E2 N [Source:NCBI gene;Acc:395006])

HSP 1 Score: 98.2117 bits (243), Expect = 9.712e-25
Identity = 47/147 (31.97%), Postives = 81/147 (55.10%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            ++I +E ++L+  P+ GI    +E        +I GP ++P+E G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + AR +T ++A  N
Sbjct:    6 RRIIKETQRLLAEPVPGIKAEPDENNARYFHVLIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLHAMNN 151
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Xenopus
Match: tep1 (telomerase associated protein 1 [Source:Xenbase;Acc:XB-GENE-495387])

HSP 1 Score: 95.9005 bits (237), Expect = 8.249e-24
Identity = 45/136 (33.09%), Postives = 78/136 (57.35%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRA 489
            +++ ++ ++L  +P  G++   +E  I    A+I GP  TP+E+G F++ +  S  YP + P   F++K+FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N +A QL  E+  EY KR 
Sbjct:    7 RRLMRDFKRLQEDPPVGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFVSKMFHPNVY-ADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRV 141
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Xenopus
Match: ube2n (ubiquitin conjugating enzyme E2 N [Source:NCBI gene;Acc:395006])

HSP 1 Score: 95.5153 bits (236), Expect = 9.370e-24
Identity = 46/142 (32.39%), Postives = 77/142 (54.23%), Query Frame = 1 
Query:   97 EIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            E ++L+  P+ GI    +E        +I GP ++P+E G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + AR +T ++A  N
Sbjct:    2 ETQRLLAEPVPGIKAEPDENNARYFHVLIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLHAMNN 142
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Xenopus
Match: ube2a (ubiquitin conjugating enzyme E2 A [Source:NCBI gene;Acc:448176])

HSP 1 Score: 95.5153 bits (236), Expect = 1.072e-23
Identity = 44/135 (32.59%), Postives = 78/135 (57.78%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKR 486
            +++ ++ ++L  +P  G++   +E  I    A+I GP  TP+E+G F++ +  +  YP + P   F++K+FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N +A QL  E+  EY KR
Sbjct:    7 RRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVY-ADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKR 140
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Mouse
Match: Ube2s (ubiquitin-conjugating enzyme E2S [Source:MGI Symbol;Acc:MGI:1925141])

HSP 1 Score: 195.282 bits (495), Expect = 1.900e-61
Identity = 89/170 (52.35%), Postives = 120/170 (70.59%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQ 564
            +ENL PH+I+ + +E+  L  +P +GI +  NE ++TD+Q  I+GP  TPY  G FR+++ L   +P   PKG+F+TKIFHPN+ P NGEICVN LK+DW+A+ GI+ + LT+KCLLI+PN ESALNEEAG+LLLE+Y EYA RARL T I+         SSG   + Q
Sbjct:    5 VENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFLTKIFHPNVGP-NGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYAARARLLTEIHG---GACSTSSGRAEATQ 170
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Mouse
Match: Ube2s (ubiquitin-conjugating enzyme E2S [Source:MGI Symbol;Acc:MGI:1925141])

HSP 1 Score: 194.512 bits (493), Expect = 3.952e-61
Identity = 85/153 (55.56%), Postives = 115/153 (75.16%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            +ENL PH+I+ + +E+  L  +P +GI +  NE ++TD+Q  I+GP  TPY  G FR+++ L   +P   PKG+F+TKIFHPN+ P NGEICVN LK+DW+A+ GI+ + LT+KCLLI+PN ESALNEEAG+LLLE+Y EYA RARL T I+ 
Sbjct:    5 VENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFLTKIFHPNVGP-NGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYAARARLLTEIHG 156
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Mouse
Match: Ube2s (ubiquitin-conjugating enzyme E2S [Source:MGI Symbol;Acc:MGI:1925141])

HSP 1 Score: 165.622 bits (418), Expect = 6.493e-51
Identity = 71/132 (53.79%), Postives = 99/132 (75.00%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQ 450
            +ENL PH+I+ + +E+  L  +P +GI +  NE ++TD+Q  I+GP  TPY  G FR+++ L   +P   PKG+F+TKIFHPN+ P NGEICVN LK+DW+A+ GI+ + LT+KCLLI+PN ESALNEEAG+
Sbjct:   21 VENLPPHIIRLVYKEVTTLTADPPDGIKVFPNEEDLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFLTKIFHPNVGP-NGEICVNVLKRDWTAELGIRHVLLTIKCLLIHPNPESALNEEAGR 151
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Mouse
Match: Ube2n (ubiquitin-conjugating enzyme E2N [Source:MGI Symbol;Acc:MGI:1934835])

HSP 1 Score: 100.523 bits (249), Expect = 1.194e-25
Identity = 48/147 (32.65%), Postives = 81/147 (55.10%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            ++I +E ++L+  P+ GI    +E        +I GP ++P+E G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + AR +T +YA  N
Sbjct:    6 RRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNN 151
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Mouse
Match: Ube2dnl1 (ubiquitin-conjugating enzyme E2D N-terminal like 1 [Source:MGI Symbol;Acc:MGI:3646570])

HSP 1 Score: 98.2117 bits (243), Expect = 9.826e-25
Identity = 52/145 (35.86%), Postives = 80/145 (55.17%), Query Frame = 1 
Query:   79 IKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            +K+I +E+     +P    +       +   QA I GP ++PY+ G F + +   N+YP + PK  FIT+I+HPNIS KNG IC++ L   WS    I K+ L++  LL  PNA+  L  E  ++  +D  EY + AR +T  +A
Sbjct:   11 LKRIQKELVAFSQDPPAHCSAGPVAENMFHWQATIMGPEDSPYQGGVFFLSIHFPNNYPFKPPKVSFITRIYHPNIS-KNGSICLDILNSKWSPTLTISKVLLSICSLLCDPNADDPLVPEIAKVYHKDLREYNRLAREWTERFA 154
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. UniProt/SwissProt
Match: sp|C3Z724|UBE2S_BRAFL (Ubiquitin-conjugating enzyme E2 S OS=Branchiostoma floridae OX=7739 GN=BRAFLDRAFT_259979 PE=3 SV=1)

HSP 1 Score: 210.69 bits (535), Expect = 9.303e-67
Identity = 101/201 (50.25%), Postives = 138/201 (68.66%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQPQVXXXXXXXXXXXXLKTNSDSNDAGPVAKK 657
            +ENL P +I+++ +E+  L  +P EG+ +  NE++ITD+QA I+GP  TPYE G+F+I+++L   +PQ  PKGFF+TKIFHPN++ KNGEICVNTLKKDW AD G+K I LT+KCLLIYPN ESALNEEAG+LLLE Y  Y++RAR+ T I+A    +T  +  N  ++ P                + + S   GP+AKK
Sbjct:    7 VENLSPQIIRQVAKEVLDLANHPPEGVKVFPNEQDITDVQATIEGPGGTPYEGGQFKIKLSLGKDFPQTPPKGFFLTKIFHPNVA-KNGEICVNTLKKDWKADLGLKHILLTIKCLLIYPNPESALNEEAGKLLLEQYDNYSERARMMTEIHAKPTTKTAPTK-NEETNCPST--------------SGTQSTSEGPMAKK 191
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. UniProt/SwissProt
Match: sp|A7SE05|UBE2S_NEMVE (Ubiquitin-conjugating enzyme E2 S OS=Nematostella vectensis OX=45351 GN=v1g237158 PE=3 SV=1)

HSP 1 Score: 207.223 bits (526), Expect = 1.324e-65
Identity = 98/170 (57.65%), Postives = 126/170 (74.12%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQ 564
            +EN  P +IK++ +EI  L  +P EGI + +N+ +ITDIQA I+GPT TPYE G F+I++ L   +P   PKGFF+TKIFHPN++ KNGEICVNTLKKDW  D GIK++ LTVKCLLI PN ESALNEEAG+LLLE Y +Y+KRA++FT I+A     +  SS N +  Q
Sbjct:    8 VENFSPQIIKQVAREIHGLTNDPPEGIKVFSNDEDITDIQASIEGPTGTPYEGGIFKIKLVLGKDFPAAPPKGFFLTKIFHPNVA-KNGEICVNTLKKDWKPDLGIKQVLLTVKCLLIVPNPESALNEEAGKLLLERYDDYSKRAKMFTEIHA---KLSASSSNNISEGQ 173
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. UniProt/SwissProt
Match: sp|B4Q2J2|UBE2S_DROYA (Ubiquitin-conjugating enzyme E2 S OS=Drosophila yakuba OX=7245 GN=GE15576 PE=3 SV=1)

HSP 1 Score: 202.601 bits (514), Expect = 1.016e-63
Identity = 92/169 (54.44%), Postives = 124/169 (73.37%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSD 561
            +ENL P  I+++ +E++++   P EGI +L NE ++TDIQA+IDGP  TPY  G FR+++ L+  +PQ  PK +F+TKIFHPN++  NGEICVNTLKKDW  D GIK I LT+KCLLI PN ESALNEEAG++LLE Y +Y++RAR+ T I+A      V +SG+   D
Sbjct:    8 VENLSPQTIRQVMRELQEMETTPPEGIKVLINESDVTDIQALIDGPAGTPYAAGVFRVKLTLNKDFPQTPPKAYFLTKIFHPNVA-ANGEICVNTLKKDWKPDLGIKHILLTIKCLLIVPNPESALNEEAGKMLLERYDDYSQRARMMTEIHAQPAKCGVGASGDAKDD 175
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. UniProt/SwissProt
Match: sp|C1C3R6|UBE2S_LITCT (Ubiquitin-conjugating enzyme E2 S OS=Lithobates catesbeianus OX=8400 GN=ube2s PE=2 SV=1)

HSP 1 Score: 200.675 bits (509), Expect = 6.282e-63
Identity = 90/157 (57.32%), Postives = 119/157 (75.80%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNN 525
            +ENL PHVI+++ +E+  L  +P EGI ++ NE +ITD+Q  I+GP  TPY  G FR+++ L   +P   PKG+F+TKIFHPN+S  NGEICVN LKKDW A+ GI+ + LT+KCLLI+PN ESALNEEAG+LLLE+Y EYA RARL T I+A  ++
Sbjct:    5 VENLPPHVIRQVYKEVSTLTPDPPEGIKIIPNEEDITDVQVSIEGPEGTPYAGGIFRMKLILGKDFPAAPPKGYFLTKIFHPNVS-SNGEICVNVLKKDWKAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYASRARLMTEIHAHSSS 160
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. UniProt/SwissProt
Match: sp|Q8AVU2|UB2SB_XENLA (Ubiquitin-conjugating enzyme E2 S-B OS=Xenopus laevis OX=8355 GN=ube2s-b PE=2 SV=1)

HSP 1 Score: 200.675 bits (509), Expect = 7.002e-63
Identity = 89/153 (58.17%), Postives = 117/153 (76.47%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            +ENL PH+I+++ +E+  L  +P EGI ++ NE +ITD+Q  I+GP  TPY  G FR+++ L   +P   PKG+F+TKIFHPN+S  NGEICVN LKKDW A+ GI+ + LT+KCLLI+PN ESALNEEAG+LLLE+Y EYA RARL T I+A
Sbjct:    5 VENLPPHIIRRVYKEVSTLTSDPPEGIKIIPNEEDITDVQVNIEGPEGTPYAGGMFRMKLILGKDFPAAPPKGYFLTKIFHPNVS-NNGEICVNVLKKDWKAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYASRARLMTDIHA 156
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. TrEMBL
Match: A0A0C9PNU7 (GG18165 protein (Fragment) OS=Fopius arisanus OX=64838 GN=GG18165 PE=3 SV=1)

HSP 1 Score: 219.55 bits (558), Expect = 3.553e-68
Identity = 98/156 (62.82%), Postives = 127/156 (81.41%), Query Frame = 1 
Query:   46 IITMENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            I  +ENL P +I+++ +E+ +LV +P EGI ++ NE ++TDIQA+I+GP ETPY NGRFR+++AL   +PQ  PK FFITKIFHPN++ KNGEICVNTLKKDW +D GIK I LTVKCLLI PNAESALNEEAG++LLE Y EY++RA++ T I+A
Sbjct:    4 ISNVENLSPQIIRRVVKEMSELVQSPPEGIRVIVNEDDVTDIQAVIEGPAETPYANGRFRVKLALGKDFPQGPPKAFFITKIFHPNVA-KNGEICVNTLKKDWKSDLGIKHILLTVKCLLIVPNAESALNEEAGKMLLEKYEEYSERAKMMTEIHA 158
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. TrEMBL
Match: H2KPG5 (Ubiquitin-conjugating enzyme E2 S OS=Clonorchis sinensis OX=79923 GN=CLF_101936 PE=3 SV=1)

HSP 1 Score: 213.386 bits (542), Expect = 4.552e-65
Identity = 89/156 (57.05%), Postives = 126/156 (80.77%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            MEN+ PHV+++I +EIR+++ + ++GI L+ NE+++TDIQAIIDGP +TPYE G+F +++ LS  YP + PKG+F TKIFHPN++P  GEICV+TLK+DW ++ G+K I L ++CLL+ PN ESALNEEAG+LL EDYTEY  +ARL+T I+A  +
Sbjct:   18 MENIYPHVVRRISKEIREVLDDTLDGIKLVVNEQDLTDIQAIIDGPADTPYEGGKFGVKLVLSERYPIEPPKGYFYTKIFHPNVAPVTGEICVDTLKRDWKSELGLKHILLVIRCLLLDPNPESALNEEAGKLLQEDYTEYVAQARLYTEIHACHH 173
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. TrEMBL
Match: A0A4V3SDQ6 (UBIQUITIN_CONJUGAT_2 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007931 PE=3 SV=1)

HSP 1 Score: 212.231 bits (539), Expect = 8.041e-65
Identity = 89/156 (57.05%), Postives = 125/156 (80.13%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            MEN+ PHV+K+I +EIR+++ + ++GI L+ NE+++TDIQAIIDGP +TPYE G+F +++ LS  YP + PKG+F TKIFHPN++P  GEICV+TLK+DW ++ G+K I L ++CLL+ PN ESALNEEAG+LL EDY EY  +ARL+T I+A  +
Sbjct:    1 MENIYPHVVKRISKEIREVLDDTLDGIKLVVNEQDLTDIQAIIDGPADTPYEGGKFGVKLVLSERYPIEPPKGYFYTKIFHPNVAPVTGEICVDTLKRDWKSELGLKHILLVIRCLLLDPNPESALNEEAGKLLQEDYAEYVAQARLYTEIHACHH 156
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. TrEMBL
Match: A0A267H1S3 (UBIQUITIN_CONJUGAT_2 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022577g2 PE=3 SV=1)

HSP 1 Score: 212.231 bits (539), Expect = 9.470e-65
Identity = 91/156 (58.33%), Postives = 123/156 (78.85%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            MEN  P V+K++ +E+R LV  P EGI +  ++ ++TDI A+IDGP +TPY  GRF IR+ + +S+PQ+ PKG+F+TKIFHPNI+  +GEICVNT+K+DW+ D G++ + L +KCLLI PNAESALN+EAG+LLLEDY EY  RARLFT ++A QN
Sbjct:    1 MENCSPSVMKRLSKEVRDLVQQPPEGIRVHFDDAKLTDIHAVIDGPVDTPYCGGRFHIRLVMGHSFPQEPPKGYFLTKIFHPNIATPSGEICVNTIKRDWTPDTGLRHLLLVIKCLLIVPNAESALNQEAGRLLLEDYAEYFSRARLFTEVHALQN 156
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. TrEMBL
Match: A0A1S8WMC5 (Ubiquitin--protein ligase (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_08651 PE=3 SV=1)

HSP 1 Score: 210.69 bits (535), Expect = 1.299e-64
Identity = 88/156 (56.41%), Postives = 125/156 (80.13%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            MEN+ PHV+++I +EIR+++ + ++GI L+ NE+++TDIQAIIDGP +TPYE G+F +++ LS  YP + PKG+F TKIFHPN++P  GEICV+TLK+DW ++ G+K I L ++CLL+ PN ESALNEEAG+LL EDY EY  +ARL+T I+A  +
Sbjct:    1 MENIYPHVVRRISKEIREVLDDTLDGIKLVVNEQDLTDIQAIIDGPADTPYEGGKFGVKLVLSERYPIEPPKGYFYTKIFHPNVAPVTGEICVDTLKRDWKSELGLKHILLVIRCLLLDPNPESALNEEAGKLLQEDYAEYVAQARLYTEIHACHH 156
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Cavefish
Match: ube2s (ubiquitin conjugating enzyme E2 S [Source:NCBI gene;Acc:103031438])

HSP 1 Score: 188.734 bits (478), Expect = 6.685e-59
Identity = 85/172 (49.42%), Postives = 116/172 (67.44%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQPQ 570
            +ENL P V++ + +E+  L  +P EGI +  +E +IT++   I+GP  TPY  G FR+R+ L   +P   P+G+F+TKIFHPN+  K GEICVN LK+DW A+ G++ + LT+KCLLI+PN ESALNEEAG+LLLEDY EYA RA L T I+A   +   +       D PQ
Sbjct:    5 VENLPPQVLRLVYKEVSALAADPPEGIKIYPSEEDITELHTAIEGPEGTPYAGGVFRMRLVLGKDFPAVPPRGYFLTKIFHPNVGHK-GEICVNVLKRDWKAELGLRHVLLTIKCLLIHPNPESALNEEAGRLLLEDYAEYASRAHLLTEIHAMGGSSGALQE---AGDGPQ 172
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Cavefish
Match: ube2na (ubiquitin conjugating enzyme E2 N [Source:NCBI gene;Acc:103021524])

HSP 1 Score: 99.3673 bits (246), Expect = 2.921e-25
Identity = 48/147 (32.65%), Postives = 81/147 (55.10%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQN 522
            ++I +E ++L+  P+ GI    +E        +I GP ++P+E G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + AR +T +YA  N
Sbjct:    6 RRIIKETQRLLAEPVPGIKAEPDEGNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARTWTRLYAGNN 151
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Cavefish
Match: ENSAMXT00000050020.1 (ubiquitin-conjugating enzyme E2 A-like [Source:NCBI gene;Acc:103029486])

HSP 1 Score: 96.2857 bits (238), Expect = 3.775e-24
Identity = 45/135 (33.33%), Postives = 78/135 (57.78%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKR 486
            +++ ++ ++L  +P  G++   +E  I    A+I GP  TP+E+G F++ +  +  YP + P   FI+K+FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N +A QL  E+  EY KR
Sbjct:    7 RRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTVEFTEEYPNKPPTVRFISKMFHPNVY-ADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKR 140
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Cavefish
Match: ube2al (ubiquitin-conjugating enzyme E2 A-like [Source:NCBI gene;Acc:103021436])

HSP 1 Score: 95.5153 bits (236), Expect = 6.308e-24
Identity = 44/135 (32.59%), Postives = 78/135 (57.78%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKR 486
            +++ ++ ++L  +P  G++   +E  I    A+I GP  TP+E+G F++ +  +  YP + P   F++K+FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N +A QL  E+  EY KR
Sbjct:    7 RRLMRDFKRLQEDPPAGVSGAPSENNIMIWNAVIFGPEGTPFEDGTFKLTVEFTEEYPNKPPTVRFVSKMFHPNVY-ADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKR 140
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Cavefish
Match: ube2a (ubiquitin conjugating enzyme E2 A [Source:NCBI gene;Acc:103035357])

HSP 1 Score: 95.5153 bits (236), Expect = 6.374e-24
Identity = 44/135 (32.59%), Postives = 78/135 (57.78%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKR 486
            +++ ++ ++L  +P  G++   +E  I    A+I GP  TP+E+G F++ +  +  YP + P   F++K+FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N +A QL  E+  EY KR
Sbjct:    7 RRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVY-ADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKR 140
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Sea Lamprey
Match: ube2s (ubiquitin-conjugating enzyme E2S [Source:NCBI gene;Acc:565498])

HSP 1 Score: 196.052 bits (497), Expect = 8.242e-63
Identity = 89/167 (53.29%), Postives = 119/167 (71.26%), Query Frame = 1 
Query:   46 IITMENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSG 546
            +  +ENL PHVI+++ +E+ +L   P EGI +  NE +ITD+QA I+GP  TPY  G FR+++ L   +P   PK +F+TKIFHPN+S  +GEICVN LKKDW A+ GI+ + LTVKCLLI+PN ESALNEEAG+LLLE Y +YA  A+L T I+A   N    ++G
Sbjct:    4 VSNVENLPPHVIRQVWKEVTELAREPPEGIKVYLNEDDITDVQATIEGPEGTPYAGGIFRMKLVLGKDFPASPPKAYFLTKIFHPNVS-SSGEICVNVLKKDWKAELGIRHVLLTVKCLLIHPNPESALNEEAGRLLLEAYEDYAAHAKLLTEIHALPANAAPTNAG 169
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008817.1 (pep scaffold:Pmarinus_7.0:GL476329:1748443:1760143:-1 gene:ENSPMAG00000007968.1 transcript:ENSPMAT00000008817.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 92.4337 bits (228), Expect = 1.959e-23
Identity = 43/135 (31.85%), Postives = 77/135 (57.04%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKR 486
            +++ ++ ++L  +P  G++   +E  I    A+I GP  TP+E+G F++ +  +  YP + P   F++K+FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N  A QL  E+  EY K+
Sbjct:    7 RRLMRDFKRLQEDPPAGVSGAPSENNIMLWNAVIFGPEGTPFEDGTFKLTLEFTEEYPNKPPTVKFVSKMFHPNVY-ADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSLAAQLYQENKREYEKK 140
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006211.1 (pep scaffold:Pmarinus_7.0:GL476897:3176:4886:1 gene:ENSPMAG00000005612.1 transcript:ENSPMAT00000006211.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 89.7373 bits (221), Expect = 1.451e-22
Identity = 43/127 (33.86%), Postives = 71/127 (55.91%), Query Frame = 1 
Query:  106 QLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKR 486
            +L  +P  G++    E  I    A+I GP  TP+E+G F++ +  +  YP + P   F++K+FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N +A QL  E+  EY K+
Sbjct:    3 RLQEDPPAGVSGAPTENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVY-ADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKK 128
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010378.1 (pep scaffold:Pmarinus_7.0:GL477318:26908:31295:-1 gene:ENSPMAG00000009396.1 transcript:ENSPMAT00000010378.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.5001 bits (210), Expect = 6.298e-21
Identity = 45/137 (32.85%), Postives = 71/137 (51.82%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRAR 492
            + + QE+  L  +P    +      ++   QA I GP ++PY+ G F + +     YP + PK  F T+I+HPNI+  NG IC++ L+  WS    I K+ L++  LL  PN +  L  E  ++   D  +Y K AR
Sbjct:    5 RPLHQELNDLGRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNIN-SNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNKLAR 140
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Sea Lamprey
Match: ube2kb (ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-980605-9])

HSP 1 Score: 78.1814 bits (191), Expect = 1.026e-17
Identity = 40/118 (33.90%), Postives = 68/118 (57.63%), Query Frame = 1 
Query:  160 ITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
             T+++  I GP +TPYE GR+ + + +  +YP   PK  FITKI+HPNIS   G IC++ LK  W+A   ++ + L+++ LL     +   +    +   E++  + + ARL+  +YA
Sbjct:   35 FTELRGEIAGPPDTPYEGGRYMLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVARQYKENHEMFVQTARLWAHMYA 152
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Yeast
Match: UBC13 (E2 ubiquitin-conjugating enzyme; involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus [Source:SGD;Acc:S000002499])

HSP 1 Score: 107.457 bits (267), Expect = 2.398e-29
Identity = 51/146 (34.93%), Postives = 87/146 (59.59%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQ 519
            K+I +E  +LV +P+ GIT   ++  +   Q  I+GP ++PYE+G F + + L + YP +APK  F+TKI+HPNI  + G IC++ LK +WS    I+ + L+++ LL  PN    L  +  +  +++      +AR +T +YA +
Sbjct:    6 KRIIKETEKLVSDPVPGITAEPHDDNLRYFQVTIEGPEQSPYEDGIFELELYLPDDYPMEAPKVRFLTKIYHPNID-RLGRICLDVLKTNWSPALQIRTVLLSIQALLASPNPNDPLANDVAEDWIKNEQGAKAKAREWTKLYAKK 150
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Yeast
Match: UBC1 (Ubiquitin-conjugating enzyme; key E2 partner with Ubc4p for the anaphase-promoting complex (APC); mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response; protein abundance increases in response to DNA replication stress key E2 partner with Ubc4p for the anaphase-promoting complex (APC) [Source:SGD;Acc:S000002584])

HSP 1 Score: 96.2857 bits (238), Expect = 2.423e-24
Identity = 51/149 (34.23%), Postives = 81/149 (54.36%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITL-LTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNN 525
            K+I +EI+ +  +P   ITL   +E +I  ++    GP  TPYE G+F + + +   YP + PK  F TK++HPNIS   G IC++ LK  WS    +K   ++++ LL  P      + E  Q  L D   + K A L+T +YA++ +
Sbjct:    5 KRIMKEIQAVKDDPAAHITLEFVSESDIHHLKGTFLGPPGTPYEGGKFVVDIEVPMEYPFKPPKMQFDTKVYHPNISSVTGAICLDILKNAWSPVITLKSALISLQALLQSPEPNDPQDAEVAQHYLRDRESFNKTAALWTRLYASETS 153
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Yeast
Match: UBC11 (Ubiquitin-conjugating enzyme; most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2 [Source:SGD;Acc:S000005866])

HSP 1 Score: 89.3521 bits (220), Expect = 2.037e-22
Identity = 46/139 (33.09%), Postives = 79/139 (56.83%), Query Frame = 1 
Query:   76 VIKKIGQEIRQLVLNPIEGITLL-TNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRA 489
            V K++  E+ QL+ +  E I+    ++ ++T     I GP +TPY   +F++ +    +YP   P   F++ ++HPN+  K+G IC++ LK+ WSA + ++ I L+++ LL  PN  S LN  A +L   D  EY K+ 
Sbjct:    9 VTKRLQNELLQLLSSTTESISAFPVDDNDLTYWVGYITGPKDTPYSGLKFKVSLKFPQNYPFHPPMIKFLSPMWHPNVD-KSGNICLDILKEKWSAVYNVETILLSLQSLLGEPNNRSPLNAVAAELWDADMEEYRKKV 146
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Yeast
Match: UBC4 (Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication [Source:SGD;Acc:S000000286])

HSP 1 Score: 87.0409 bits (214), Expect = 1.355e-21
Identity = 48/144 (33.33%), Postives = 72/144 (50.00%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            K+I +E+  L  +P    +      ++   QA I GP ++PY  G F + +     YP + PK  F TKI+HPNI+  NG IC++ LK  WS    + K+ L++  LL   N +  L  E   +   D  +Y   AR +T  YA
Sbjct:    5 KRIAKELSDLERDPPTSCSAGPVGDDLYHWQASIMGPADSPYAGGVFFLSIHFPTDYPFKPPKISFTTKIYHPNIN-ANGNICLDILKDQWSPALTLSKVLLSICSLLTDANPDDPLVPEIAHIYKTDRPKYEATAREWTKKYA 147
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Yeast
Match: RAD6 (Ubiquitin-conjugating enzyme (E2); involved in postreplication repair as a heterodimer with Rad18p, regulation of K63 polyubiquitination in response to oxidative stress, DSBR and checkpoint control as a heterodimer with Bre1p, ubiquitin-mediated N-end rule protein degradation as a heterodimer with Ubr1p, ERAD with Ubr1p in the absence of canonical ER membrane ligases, and Rpn4p turnover as part of proteasome homeostasis, in complex with Ubr2p and Mub1p [Source:SGD;Acc:S000003026])

HSP 1 Score: 87.0409 bits (214), Expect = 2.228e-21
Identity = 38/106 (35.85%), Postives = 62/106 (58.49%), Query Frame = 1 
Query:  175 AIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRAR 492
            A+I GP +TPYE+G FR+ +     YP + P   F++++FHPN+   NGEIC++ L+  W+  + +  I  +++ L   PN  S  N EA  L  +  ++Y KR +
Sbjct:   38 AMIIGPADTPYEDGTFRLLLEFDEEYPNKPPHVKFLSEMFHPNVY-ANGEICLDILQNRWTPTYDVASILTSIQSLFNDPNPASPANVEAATLFKDHKSQYVKRVK 142
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Nematostella
Match: EDO38105 (Ubiquitin-conjugating enzyme E2 S [Source:UniProtKB/Swiss-Prot;Acc:A7SE05])

HSP 1 Score: 207.223 bits (526), Expect = 5.426e-67
Identity = 98/170 (57.65%), Postives = 126/170 (74.12%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQ 564
            +EN  P +IK++ +EI  L  +P EGI + +N+ +ITDIQA I+GPT TPYE G F+I++ L   +P   PKGFF+TKIFHPN++ KNGEICVNTLKKDW  D GIK++ LTVKCLLI PN ESALNEEAG+LLLE Y +Y+KRA++FT I+A     +  SS N +  Q
Sbjct:    8 VENFSPQIIKQVAREIHGLTNDPPEGIKVFSNDEDITDIQASIEGPTGTPYEGGIFKIKLVLGKDFPAAPPKGFFLTKIFHPNVA-KNGEICVNTLKKDWKPDLGIKQVLLTVKCLLIVPNPESALNEEAGKLLLERYDDYSKRAKMFTEIHA---KLSASSSNNISEGQ 173
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Nematostella
Match: EDO40595 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6Q0])

HSP 1 Score: 100.908 bits (250), Expect = 2.237e-26
Identity = 48/144 (33.33%), Postives = 81/144 (56.25%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            ++I +E ++LV  P+ GI  + +E         ++GP ++PYE G F++ + L   YP  APK  F+TKI+HPNI  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + A+ +T +YA
Sbjct:    8 RRIIKETQRLVAEPVAGIQAVPDESNARYFHVTVNGPKDSPYEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNID-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKVNEVQAIETAKAWTRLYA 150
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Nematostella
Match: EDO31327 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6Q0])

HSP 1 Score: 100.908 bits (250), Expect = 2.237e-26
Identity = 48/144 (33.33%), Postives = 81/144 (56.25%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
            ++I +E ++LV  P+ GI  + +E         ++GP ++PYE G F++ + L   YP  APK  F+TKI+HPNI  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + A+ +T +YA
Sbjct:    8 RRIIKETQRLVAEPVAGIQAVPDESNARYFHVTVNGPKDSPYEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNID-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKVNEVQAIETAKAWTRLYA 150
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Nematostella
Match: EDO43669 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXR8])

HSP 1 Score: 88.1965 bits (217), Expect = 1.304e-21
Identity = 47/146 (32.19%), Postives = 76/146 (52.05%), Query Frame = 1 
Query:   76 VIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
             +K+I +E++ L  +P    +      ++   QA I GP ++PY+ G F + +     YP + PK  F TKI+HPNI+  NG IC++ L+  WS    I K+ L++  L+  PN +  L  E  +    D  +Y   A+ +T  YA
Sbjct:    2 ALKRINKELQDLGRDPPAQCSAGPVGDDLFHWQATIMGPADSPYQGGVFFLTIHFPTDYPFKPPKVSFTTKIYHPNIN-SNGSICLDILRSQWSPALTISKVLLSICSLMDDPNPDDPLVPEIARSFKTDRKKYNDMAKEWTRKYA 146
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Nematostella
Match: EDO39550 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Q6])

HSP 1 Score: 88.1965 bits (217), Expect = 4.953e-21
Identity = 43/153 (28.10%), Postives = 81/153 (52.94%), Query Frame = 1 
Query:   79 IKKIGQEIRQLVLNPIE---GITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQ 528
            + ++ +E R+++ +  +   GI +   +   T ++  I GP ETP+E G + + + +  +YP   PK  F TKI+HPNIS   G IC++ LK  W+A   ++ + L+++ LL  P  +   +    +   E+ + Y   AR +  ++A   +Q
Sbjct:    6 VSRVKREFREIITSEEDQKSGIKVELVDETFTKLKGEIRGPPETPFEGGTYNLDIVIPETYPFNPPKVKFTTKIWHPNISSVTGAICLDILKDQWAAAMTLRTVMLSIQALLASPEPDDPQDAVVARQFKENRSAYLLTARHWAQVHAGAKSQ 158
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Medaka
Match: ube2s (ubiquitin conjugating enzyme E2 S [Source:NCBI gene;Acc:101164429])

HSP 1 Score: 188.734 bits (478), Expect = 6.282e-59
Identity = 88/172 (51.16%), Postives = 116/172 (67.44%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQPQ 570
            +ENL PHV++ + +E+  L  +P EGI +  +E +IT++   I+GP  TP+  G FR+R+ L   +P   PKG+F+TKIFHPN+  K GEICVN LK+DW A+ G++ I LT+KCLLI+PN ESALNEEAG+LLLEDY EY  RARL T I+A           N   D PQ
Sbjct:    5 VENLPPHVLRLVYKEVSALAADPPEGIKIYPSEEDITELHTSIEGPEGTPFAGGIFRMRLVLGKDFPAVPPKGYFLTKIFHPNVGHK-GEICVNVLKRDWKAELGLRHILLTIKCLLIHPNPESALNEEAGRLLLEDYAEYESRARLLTEIHAMGGTSGAPQDPN---DGPQ 172
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Medaka
Match: ENSORLT00000014143.2 (ubiquitin conjugating enzyme E2 N [Source:NCBI gene;Acc:101166376])

HSP 1 Score: 99.7525 bits (247), Expect = 1.790e-25
Identity = 48/150 (32.00%), Postives = 81/150 (54.00%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQT 531
            ++I +E ++L+  P+ GI    +E        +I GP ++P+E G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  E    A+ +T +YA   N+ 
Sbjct:    6 RRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEKWKSNEAEAIDIAKTWTRLYAGNKNEV 154
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Medaka
Match: ENSORLT00000038091.1 (ubiquitin-conjugating enzyme E2 N [Source:NCBI gene;Acc:101170318])

HSP 1 Score: 99.7525 bits (247), Expect = 1.936e-25
Identity = 48/145 (33.10%), Postives = 81/145 (55.86%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYAT 516
            ++I +E ++L+  P+ GIT   +E        II GP ++PYE G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +   +      + A+ +T ++A+
Sbjct:    6 RRIIKETQRLMAEPVPGITATPDEGNARYFHVIIAGPQDSPYEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKKHEMHAIETAQTWTRLFAS 149
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Medaka
Match: ENSORLT00000028457.1 (ubiquitin-conjugating enzyme E2 N [Source:NCBI gene;Acc:101170318])

HSP 1 Score: 96.2857 bits (238), Expect = 3.071e-24
Identity = 45/123 (36.59%), Postives = 71/123 (57.72%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQ 450
            ++I +E ++L+  P+ GIT   +E        II GP ++PYE G F++ + L   YP  APK  F+TKI+HPN+  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +
Sbjct:    6 RRIIKETQRLMAEPVPGITATPDEGNARYFHVIIAGPQDSPYEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVD-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAE 127
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Medaka
Match: ube2b (ubiquitin conjugating enzyme E2 B [Source:NCBI gene;Acc:101172675])

HSP 1 Score: 95.9005 bits (237), Expect = 5.137e-24
Identity = 44/136 (32.35%), Postives = 78/136 (57.35%), Query Frame = 1 
Query:   82 KKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRA 489
            +++ ++ ++L  +P  G++   +E  I    A+I GP  TP+E+G F++ +  S  YP + P   F++++FHPN+   +G IC++ L+  WS  + +  I  +++ LL  PN  S  N +A QL  E+  EY KR 
Sbjct:    7 RRLMRDFKRLQEDPPTGVSGAPSENNIMLWNAVIFGPVGTPFEDGTFKLLIEFSEEYPNKPPTVRFVSRMFHPNVY-ADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRV 141
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Planmine SMEST
Match: SMESG000043009.1 (SMESG000043009.1)

HSP 1 Score: 404.445 bits (1038), Expect = 6.038e-144
Identity = 224/225 (99.56%), Postives = 224/225 (99.56%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQPQVXXXXXXXXXXXXLKTNSDSNDAGPVAKKLXXXXXXXXXXXXXXAQKRPVPQH 729
            MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKI LTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQPQVSNSANSTSINTILKTNSDSNDAGPVAKKLNSNEHSSNISSESSAQKRPVPQH
Sbjct:    1 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKILLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQPQVSNSANSTSINTILKTNSDSNDAGPVAKKLNSNEHSSNISSESSAQKRPVPQH 225
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Planmine SMEST
Match: SMESG000007604.1 (SMESG000007604.1)

HSP 1 Score: 404.445 bits (1038), Expect = 6.038e-144
Identity = 224/225 (99.56%), Postives = 224/225 (99.56%), Query Frame = 1 
Query:   55 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQPQVXXXXXXXXXXXXLKTNSDSNDAGPVAKKLXXXXXXXXXXXXXXAQKRPVPQH 729
            MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKI LTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQPQVSNSANSTSINTILKTNSDSNDAGPVAKKLNSNEHSSNISSESSAQKRPVPQH
Sbjct:    1 MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKILLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTVMSSGNFTSDQPQVSNSANSTSINTILKTNSDSNDAGPVAKKLNSNEHSSNISSESSAQKRPVPQH 225
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Planmine SMEST
Match: SMESG000045122.1 (SMESG000045122.1)

HSP 1 Score: 107.457 bits (267), Expect = 1.367e-28
Identity = 52/150 (34.67%), Postives = 89/150 (59.33%), Query Frame = 1 
Query:   85 KIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYATQNNQTV 534
            +I +E ++L+  P+EGI  + NE        +++GP ++PYE G F++ + L + YP  APK  F+TKI+HPNI  K G IC++ LK  WS    I+ + L+++ LL  PN +  L  +  +    +  +  + AR +T+I+A+  NQ++
Sbjct:    8 RIIKETQRLMKEPVEGIKAIPNEENARYFHVLVNGPKDSPYEGGVFKLELFLPDEYPMSAPKVRFVTKIYHPNID-KLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKMNEVDAIRTAREWTAIHAS--NQSL 154
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Planmine SMEST
Match: SMESG000063640.1 (SMESG000063640.1)

HSP 1 Score: 100.908 bits (250), Expect = 4.160e-26
Identity = 52/147 (35.37%), Postives = 80/147 (54.42%), Query Frame = 1 
Query:   76 VIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYAT 516
             +K+I  E++ L+ +P    +    E ++    A I GP ++PYE G F + +     YP + P   F TKIFHPNI+  NG IC++ LK  WS    I K+ L++  LL  PNA+  L+  A  L  +D  ++ + AR +T  YA+
Sbjct:    2 ALKRIQTELKSLMTDPPAQCSAGPKESDLVHWSATIMGPADSPYEGGIFSLSIEFPPDYPFKPPMVKFDTKIFHPNIN-SNGSICLDILKGQWSPALTISKVLLSICSLLCDPNADDPLDSNAANLYKKDRKKFDETARSWTMKYAS 147
[Close]
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Planmine SMEST
Match: SMESG000064169.1 (SMESG000064169.1)

HSP 1 Score: 94.3597 bits (233), Expect = 1.120e-23
Identity = 49/146 (33.56%), Postives = 78/146 (53.42%), Query Frame = 1 
Query:   76 VIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETPYENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDWSADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTSIYA 513
             +K+IG+E++ L  +P    +      ++   QA I GP ++PY+ G F + +     YP + PK  F TKI+HPNI+  NG IC++ L+  WS    I K+ L++  LL  PN +  L  E  ++   D  +Y   A+ +T  YA
Sbjct:    2 ALKRIGRELQDLAKDPPAQCSAGPMHEDLFHWQATIMGPNDSPYDGGVFFLDIQFPTDYPFKPPKVTFTTKIYHPNIN-ANGSICLDILRGQWSPALTISKVLLSICSLLTDPNPDDPLVPEIARIYKNDRKKYNDTAQDWTRKYA 146
The following BLAST results are available for this feature:
BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
UBE2S1.348e-6054.90ubiquitin conjugating enzyme E2 S [Source:HGNC Sym... [more]
UBE2S2.504e-5446.15ubiquitin conjugating enzyme E2 S [Source:HGNC Sym... [more]
UBE2N1.739e-2532.65ubiquitin conjugating enzyme E2 N [Source:HGNC Sym... [more]
UBE2B5.277e-2433.09ubiquitin conjugating enzyme E2 B [Source:HGNC Sym... [more]
UBE2A1.182e-2332.59ubiquitin conjugating enzyme E2 A [Source:HGNC Sym... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ubc-139.610e-2534.03Ubiquitin-conjugating enzyme E2 13 [Source:UniPro... [more]
ubc-11.157e-2434.31Ubiquitin-conjugating enzyme E2 1 [Source:UniProt... [more]
let-701.427e-2233.56Ubiquitin-conjugating enzyme E2 2 [Source:UniProt... [more]
ubc-212.567e-2232.03Probable ubiquitin-conjugating enzyme E2 21 [Sour... [more]
ubc-87.206e-2238.05UBiquitin Conjugating enzyme [Source:UniProtKB/Tr... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG81881.398e-6253.25gene:FBgn0030863 transcript:FBtr0346186[more]
CG81881.398e-6253.25gene:FBgn0030863 transcript:FBtr0100463[more]
CG81881.398e-6253.25gene:FBgn0030863 transcript:FBtr0074476[more]
CG81881.398e-6253.25gene:FBgn0030863 transcript:FBtr0340633[more]
ben9.483e-2834.69gene:FBgn0000173 transcript:FBtr0307296[more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2s1.609e-5753.59ubiquitin-conjugating enzyme E2S [Source:NCBI gene... [more]
ube2s1.683e-5753.59ubiquitin-conjugating enzyme E2S [Source:NCBI gene... [more]
ube2nb2.060e-2532.65ubiquitin-conjugating enzyme E2Nb [Source:ZFIN;Acc... [more]
ube2na3.447e-2532.65ubiquitin-conjugating enzyme E2Na [Source:ZFIN;Acc... [more]
CR753897.13.505e-2533.11pep chromosome:GRCz11:CHR_ALT_CTG18_2_4:15781720:1... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2s5.130e-6358.17ubiquitin conjugating enzyme E2 S [Source:NCBI gen... [more]
ube2n9.712e-2531.97ubiquitin conjugating enzyme E2 N [Source:NCBI gen... [more]
tep18.249e-2433.09telomerase associated protein 1 [Source:Xenbase;Ac... [more]
ube2n9.370e-2432.39ubiquitin conjugating enzyme E2 N [Source:NCBI gen... [more]
ube2a1.072e-2332.59ubiquitin conjugating enzyme E2 A [Source:NCBI gen... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ube2s1.900e-6152.35ubiquitin-conjugating enzyme E2S [Source:MGI Symbo... [more]
Ube2s3.952e-6155.56ubiquitin-conjugating enzyme E2S [Source:MGI Symbo... [more]
Ube2s6.493e-5153.79ubiquitin-conjugating enzyme E2S [Source:MGI Symbo... [more]
Ube2n1.194e-2532.65ubiquitin-conjugating enzyme E2N [Source:MGI Symbo... [more]
Ube2dnl19.826e-2535.86ubiquitin-conjugating enzyme E2D N-terminal like 1... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|C3Z724|UBE2S_BRAFL9.303e-6750.25Ubiquitin-conjugating enzyme E2 S OS=Branchiostoma... [more]
sp|A7SE05|UBE2S_NEMVE1.324e-6557.65Ubiquitin-conjugating enzyme E2 S OS=Nematostella ... [more]
sp|B4Q2J2|UBE2S_DROYA1.016e-6354.44Ubiquitin-conjugating enzyme E2 S OS=Drosophila ya... [more]
sp|C1C3R6|UBE2S_LITCT6.282e-6357.32Ubiquitin-conjugating enzyme E2 S OS=Lithobates ca... [more]
sp|Q8AVU2|UB2SB_XENLA7.002e-6358.17Ubiquitin-conjugating enzyme E2 S-B OS=Xenopus lae... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0C9PNU73.553e-6862.82GG18165 protein (Fragment) OS=Fopius arisanus OX=6... [more]
H2KPG54.552e-6557.05Ubiquitin-conjugating enzyme E2 S OS=Clonorchis si... [more]
A0A4V3SDQ68.041e-6557.05UBIQUITIN_CONJUGAT_2 domain-containing protein OS=... [more]
A0A267H1S39.470e-6558.33UBIQUITIN_CONJUGAT_2 domain-containing protein OS=... [more]
A0A1S8WMC51.299e-6456.41Ubiquitin--protein ligase (Fragment) OS=Opisthorch... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2s6.685e-5949.42ubiquitin conjugating enzyme E2 S [Source:NCBI gen... [more]
ube2na2.921e-2532.65ubiquitin conjugating enzyme E2 N [Source:NCBI gen... [more]
ENSAMXT00000050020.13.775e-2433.33ubiquitin-conjugating enzyme E2 A-like [Source:NCB... [more]
ube2al6.308e-2432.59ubiquitin-conjugating enzyme E2 A-like [Source:NCB... [more]
ube2a6.374e-2432.59ubiquitin conjugating enzyme E2 A [Source:NCBI gen... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2s8.242e-6353.29ubiquitin-conjugating enzyme E2S [Source:NCBI gene... [more]
ENSPMAT00000008817.11.959e-2331.85pep scaffold:Pmarinus_7.0:GL476329:1748443:1760143... [more]
ENSPMAT00000006211.11.451e-2233.86pep scaffold:Pmarinus_7.0:GL476897:3176:4886:1 gen... [more]
ENSPMAT00000010378.16.298e-2132.85pep scaffold:Pmarinus_7.0:GL477318:26908:31295:-1 ... [more]
ube2kb1.026e-1733.90ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, y... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
UBC132.398e-2934.93E2 ubiquitin-conjugating enzyme; involved in the e... [more]
UBC12.423e-2434.23Ubiquitin-conjugating enzyme; key E2 partner with ... [more]
UBC112.037e-2233.09Ubiquitin-conjugating enzyme; most similar in sequ... [more]
UBC41.355e-2133.33Ubiquitin-conjugating enzyme (E2); key E2 partner ... [more]
RAD62.228e-2135.85Ubiquitin-conjugating enzyme (E2); involved in pos... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO381055.426e-6757.65Ubiquitin-conjugating enzyme E2 S [Source:UniProt... [more]
EDO405952.237e-2633.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO313272.237e-2633.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO436691.304e-2132.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO395504.953e-2128.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2s6.282e-5951.16ubiquitin conjugating enzyme E2 S [Source:NCBI gen... [more]
ENSORLT00000014143.21.790e-2532.00ubiquitin conjugating enzyme E2 N [Source:NCBI gen... [more]
ENSORLT00000038091.11.936e-2533.10ubiquitin-conjugating enzyme E2 N [Source:NCBI gen... [more]
ENSORLT00000028457.13.071e-2436.59ubiquitin-conjugating enzyme E2 N [Source:NCBI gen... [more]
ube2b5.137e-2432.35ubiquitin conjugating enzyme E2 B [Source:NCBI gen... [more]
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BLAST of Ubiquitin-conjugating enzyme E2 S vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000043009.16.038e-14499.56SMESG000043009.1[more]
SMESG000007604.16.038e-14499.56SMESG000007604.1[more]
SMESG000045122.11.367e-2834.67SMESG000045122.1[more]
SMESG000063640.14.160e-2635.37SMESG000063640.1[more]
SMESG000064169.11.120e-2333.56SMESG000064169.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027390 ID=SMED30027390|Name=Ubiquitin-conjugating enzyme E2 S|organism=Schmidtea mediterranea sexual|type=transcript|length=883bp
TTTATAATTAGTATATAAATTGAAAAGTTATCATTTTCTAAATAAATCAT
TACAATGGAAAATTTATTGCCCCATGTAATTAAAAAAATCGGACAAGAAA
TACGCCAGTTGGTTTTAAATCCTATTGAAGGAATCACGTTATTAACTAAC
GAACGTGAAATAACTGACATTCAGGCAATAATTGATGGTCCAACGGAAAC
TCCATACGAAAATGGTAGATTTAGAATACGAATGGCTTTATCCAATTCAT
ATCCACAACAAGCTCCTAAAGGATTTTTTATAACCAAAATATTTCATCCA
AATATTTCACCAAAAAACGGTGAAATTTGCGTAAATACTCTTAAGAAAGA
TTGGTCGGCGGATTTTGGAATTAAGAAAATATTTTTGACTGTAAAATGCT
TATTGATTTATCCAAATGCGGAATCTGCTCTGAACGAAGAAGCCGGTCAA
TTATTATTGGAAGATTACACAGAGTATGCGAAAAGAGCAAGACTATTCAC
AAGTATTTATGCTACACAAAACAATCAAACTGTGATGAGTTCGGGAAATT
TCACATCTGACCAACCACAAGTCTCCAATTCTGCAAATAGCACATCAATA
AATACAATATTAAAAACGAACTCCGACAGTAATGATGCTGGCCCAGTTGC
CAAGAAATTGAATTCAAATGAACATTCGAGCAATATATCATCAGAATCAA
GTGCCCAAAAACGACCAGTTCCGCAACACAAAAAAGCTTTGAGGCGGCTG
TAATACTTATAAAAATTGTATACAAATATTTATTAAGGAGCGAGTATAAT
TATTTGTTGAAAATATGAAATTAGTGTTTTTATTTGCGTATGATTATTTT
ATTATTATTACTTTTTTAAAATGCTAATTGGCC
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protein sequence of SMED30027390-orf-1

>SMED30027390-orf-1 ID=SMED30027390-orf-1|Name=SMED30027390-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=233bp
MENLLPHVIKKIGQEIRQLVLNPIEGITLLTNEREITDIQAIIDGPTETP
YENGRFRIRMALSNSYPQQAPKGFFITKIFHPNISPKNGEICVNTLKKDW
SADFGIKKIFLTVKCLLIYPNAESALNEEAGQLLLEDYTEYAKRARLFTS
IYATQNNQTVMSSGNFTSDQPQVSNSANSTSINTILKTNSDSNDAGPVAK
KLNSNEHSSNISSESSAQKRPVPQHKKALRRL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000499cell
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
Vocabulary: INTERPRO
TermDefinition
IPR016135UBQ-conjugating_enzyme/RWD
IPR000608UBQ-conjugat_E2
IPR023313UBQ-conjugating_AS
Vocabulary: biological process
TermDefinition
GO:0070979protein K11-linked ubiquitination
GO:1904668positive regulation of ubiquitin protein ligase activity
GO:0000209protein polyubiquitination
GO:0006511ubiquitin-dependent protein catabolic process
GO:0007049cell cycle
GO:0010458exit from mitosis
GO:0010994free ubiquitin chain polymerization
GO:0016567protein ubiquitination
GO:0031145anaphase-promoting complex-dependent catabolic process
GO:0051301cell division
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0005524ATP binding
GO:0016740transferase activity
GO:0031625ubiquitin protein ligase binding
GO:0061630ubiquitin protein ligase activity
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005680anaphase-promoting complex
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableSMARTSM00212ubc_7coord: 10..154
e-value: 3.1E-45
score: 166.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 201..219
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 201..232
NoneNo IPR availablePANTHERPTHR24068FAMILY NOT NAMEDcoord: 2..179
NoneNo IPR availablePANTHERPTHR24068:SF126UBIQUITIN-CONJUGATING ENZYME E2 Scoord: 2..179
IPR000608Ubiquitin-conjugating enzyme E2PFAMPF00179UQ_concoord: 13..147
e-value: 4.4E-35
score: 120.4
IPR000608Ubiquitin-conjugating enzyme E2PROSITEPS50127UBIQUITIN_CONJUGAT_2coord: 10..143
score: 30.717
IPR000608Ubiquitin-conjugating enzyme E2CDDcd00195UBCccoord: 9..149
e-value: 8.48337E-44
score: 142.341
IPR016135Ubiquitin-conjugating enzyme/RWD-likeGENE3DG3DSA:3.10.110.10coord: 1..153
e-value: 9.9E-49
score: 166.8
IPR016135Ubiquitin-conjugating enzyme/RWD-likeSUPERFAMILYSSF54495UBC-likecoord: 5..154
IPR023313Ubiquitin-conjugating enzyme, active sitePROSITEPS00183UBIQUITIN_CONJUGAT_1coord: 80..96