Isoleucine--tRNA ligase

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESES--VRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF+YF+K K E GAF ++ D+YV E  GTGVVHQAPYFG +DYRVC+   IIRK    VCPVD  G FT EVT F G YVK ADK II+ LKE+ RL    T  HSYPFCWRSDTPL+ KAVPSWF+RVE++VDQLL  N   YWVP+ V+E RF NWLKDARDW ISRNRYWGTP+PLWVSDD+EEVVC+GS+AELE LSG K+ DLHRES+D + IPS+  KG L R+ EVFDCWFESGSMPYAQVH+PF    ++F + FPADFIAEGIDQTRGWFYTL V++T +FG+ PFKN++ +G+VLASDGQKMSKR KNYPDP+ +I KYGADALRLY+I+SPVVR ++L+F E GVRD++KD  +PW+N+++FL  + L     ++      L+  NT  ++ N+ D WI+SF QSLI FF  +M+ Y L TV PRL+K++D LTNWYVRMNR+RL+GE  +  ED + A+ TLF VL     +++P+ PF+TE  YQ LK  +D   + D        K   S+HY+M+P   ++LI    E +V+ MQ+++ELGR IRD+KT+ +K PL E+V++ QD +++K I+S+E Y++EELNV+K+TLS DK KY + LRAE +H +LG +LK  ++AV+ + K L++E+LE+FQ T  I + GHEL  ED+ ++ T +     T  Q+E+ S     LVL+D      ++ E +ARE+INRIQ+ RK+ NL+P D +T+Y  ++SE   + +V ESH E I+ TI  P+
Sbjct:  171 GAYLKGKKYRPLFDYFLKCK-ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENK-REFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFLIQNVL---RLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGE--NGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQD--------KDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGT-AQFEAHSDAQA-LVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLNSVIESHTEFIFTTIKAPL 931          

Query:  371 MGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFK-SNQVEIVDR 871
            MGIT YNN+CR+IVM+YS +W+  VSRLGRWIDF  DYKT+YP FMESVW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSV VTFPL +D +  L+AWTTTPWTLPSNLA+CVNP++ YVK+K+V  G+L I+ME+R+  ++K  +  EI++R
Sbjct:    1 MGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLSALYKLESDYEILER 168          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESES--VRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF+YF+K K E GAF ++ D+YV E  GTGVVHQAPYFG +DYRVC+   IIRK    VCPVD  G FT EVT F G YVK ADK II+ LKE+ RL    T  HSYPFCWRSDTPL+ KAVPSWF+RVE++VDQLL  N   YWVP+ V+E RF NWLKDARDW ISRNRYWGTP+PLWVSDD+EEVVC+GS+AELE LSG K+ DLHRES+D + IPS+  KG L R+ EVFDCWFESGSMPYAQVH+PF    ++F + FPADFIAEGIDQTRGWFYTL V++T +FG+ PFKN++ +G+VLASDGQKMSKR KNYPDP+ +I KYGADALRLY+I+SPVVR ++L+F E GVRD++KD  +PW+N+++FL  + L     ++      L+  NT  ++ N+ D WI+SF QSLI FF  +M+ Y L TV PRL+K++D LTNWYVRMNR+RL+GE  +  ED + A+ TLF VL     +++P+ PF+TE  YQ LK  +D   + D        K   S+HY+M+P   ++LI    E +V+ MQ+++ELGR IRD+KT+ +K PL E+V++ QD +++K I+S+E Y++EELNV+K+TLS DK KY + LRAE +H +LG +LK  ++AV+ + K L++E+LE+FQ T  I + GHEL  ED+ ++ T +     T  Q+E+ S     LVL+D      ++ E +ARE+INRIQ+ RK+ NL+P D +T+Y  ++SE   + +V ESH E I+ TI  P+
Sbjct:  281 GAYLKGKKYRPLFDYFLKCK-ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENK-REFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFLIQNVL---RLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGE--NGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQD--------KDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGT-AQFEAHSDAQA-LVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLNSVIESHTEFIFTTIKAPL 1041          

Query:   59 EAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFK-SNQVEIVDR 871
            E I+F  EE+ IL++W E   F+ CL+QSKHK K++FYDGPPFATG+PHYGH+LAG++KDIVTR+AHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGIT YNN+CR+IVM+YS +W+  VSRLGRWIDF  DYKT+YP FMESVW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSV VTFPL +D +  L+AWTTTPWTLPSNLA+CVNP++ YVK+K+V  G+L I+ME+R+  ++K  +  EI++R
Sbjct:    7 ENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLSALYKLESDYEILER 278          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESES--VRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF+YF+K K E GAF ++ D+YV E  GTGVVHQAPYFG +DYRVC+   IIRK    VCPVD  G FT EVT F G YVK ADK II+ LKE+ RL    T  HSYPFCWRSDTPL+ KAVPSWF+RVE++VDQLL  N   YWVP+ V+E RF NWLKDARDW ISRNRYWGTP+PLWVSDD+EEVVC+GS+AELE LSG K+ DLHRES+D + IPS+  KG L R+ EVFDCWFESGSMPYAQVH+PF    ++F + FPADFIAEGIDQTRGWFYTL V++T +FG+ PFKN++ +G+VLASDGQKMSKR KNYPDP+ +I KYGADALRLY+I+SPVVR ++L+F E GVRD++KD  +PW+N+++FL  + L     ++      L+  NT  ++ N+ D WI+SF QSLI FF  +M+ Y L TV PRL+K++D LTNWYVRMNR+RL+GE  +  ED + A+ TLF VL     +++P+ PF+TE  YQ LK  +D   + D        K   S+HY+M+P   ++LI    E +V+ MQ+++ELGR IRD+KT+ +K PL E+V++ QD +++K I+S+E Y++EELNV+K+TLS DK KY + LRAE +H +LG +LK  ++AV+ + K L++E+LE+FQ T  I + GHEL  ED+ ++ T +     T  Q+E+ S     LVL+D      ++ E +ARE+INRIQ+ RK+ NL+P D +T+Y  ++SE   + +V ESH E I+ TI  P+
Sbjct:  281 GAYLKGKKYRPLFDYFLKCK-ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENK-REFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFLIQNVL---RLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGE--NGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQD--------KDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGT-AQFEAHSDAQA-LVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLNSVIESHTEFIFTTIKAPL 1041          

Query:   59 EAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFK-SNQVEIVDR 871
            E I+F  EE+ IL++W E   F+ CL+QSKHK K++FYDGPPFATG+PHYGH+LAG++KDIVTR+AHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGIT YNN+CR+IVM+YS +W+  VSRLGRWIDF  DYKT+YP FMESVW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSV VTFPL +D +  L+AWTTTPWTLPSNLA+CVNP++ YVK+K+V  G+L I+ME+R+  ++K  +  EI++R
Sbjct:    7 ENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLSALYKLESDYEILER 278          

Query:   59 EAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFK-SNQVEIVDRVASCNTKN 895
            E I+F  EE+ IL++W E   F+ CL+QSKHK K++FYDGPPFATG+PHYGH+LAG++KDIVTR+AHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGIT YNN+CR+IVM+YS +W+  VSRLGRWIDF  DYKT+YP FMESVW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSV VTFPL +D +  L+AWTTTPWTLPSNLA+CVNP++ YVK+K+V  G+L I+ME+R+  ++K  +  EI++R      K 
Sbjct:    7 ENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLSALYKLESDYEILERFPGAYLKG 286          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFG 1020
            G  L+ K+Y PLF+YF+K K E GAF ++ D+YV E  GTGVVHQAPYFG
Sbjct:  281 GAYLKGKKYRPLFDYFLKCK-ENGAFTVLVDNYVKEEEGTGVVHQAPYFG 329          

Query:  943 AFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFT--------NEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLK--DARD-WAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKM----------NKGVLRRVP--EVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFP-----ADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVIN---------KYGADALRLYMISSPVVRGQSL-KFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNT---PPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIK--YIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVM-ISPFVPFITEFFYQRL 2403
            A  ++  ++VT + GTG+VH AP  G +DY V   + +      + C VDE G FT        N+    EG  V      +I+ L+  K L       HSYP+ WR+  P++ +A   WFI + DI     TA  E      F+  +     ++  D R  W ISR R WG P+P++     +E +      E      VK+ + H   I   + P ++              L  VP  ++ D WF+SG+                ++ + P     AD   EG DQ  GWF +  + S     +AP+K ++  G  L   G+KMSK L N   P  V+N          YGAD LR ++  S V    ++   V +  RD I        N+ +FL              G    F P T   P     ++D++++   Q L         +Y    V  RL++  Y  +L+N+Y  + + RL  E    N+    +  T    +    V   +P +P + E  +Q +
Sbjct:  373 ASPLLPANHVTMAKGTGLVHTAPAHGMEDYGVASQHNL-----PMDCLVDEDGVFTDVAGPELQNKAVLEEGTDV------VIKMLQTAKNLLKEEKLVHSYPYDWRTKKPVVIRASKQWFINITDIK----TAAKELLKKVKFIPGSALNGMVEMMDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTE----HIVKLVEQHGSDIWWTLPPEQLLPKEVLSEVGGPDALEYVPGQDILDIWFDSGT---------------SWSYVLPGPDQRADLYLEGKDQLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQSKEPPYGADVLRWWVADSNVFTEVAIGPSVLNAARDDISKL----RNTLRFLL-------------GNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQYDFGKVV-RLLRTFYTRELSNFYFSIIKDRLYCE--KENDPKRRSCQTALVEILDVIVRSFAPILPHLAEEVFQHI 849          

Query:  140 QSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXX-----------XSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQV--EIVDRVASCNTKN 895
            + K K ++  +DGPP+A G PH GH L   +KDI  RF       +    GWDCHG+PIE ++  +L      +   +       + RS      +  +    R G   D+   Y T    +       F Q+++KGLVYR  K + +S +  T L+  E + N + V+  S+ V FPL   S         +               P+N A+C  P+  Y  VK  K+G L+++   ++  V  + +   E +  ++  + +N
Sbjct:  102 ERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLPIEIKVLSELG----REAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEYNPEHVSR-SIYVKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKYAVVKCSKSGDLYVLAADKVASVASTLETTFETISTLSGVDLEN 361          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTE-QLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECS----ILSDTSGTSSEVKDSILSMWFTHDHNRLKTDNRKCLPKSSNVEVICDGDLNSVVQLDVMGIDSWDELLRHVRVAFE-WRRFAVAPVTLLDVNDKPIAP-VAPSTLKGQ 3564
            G +L+   Y PLF YF  M++E  AFR++ D++VT  SGTGVVHQAPYFGE D++VC++NG+I K   ++CPVDE GK+T+EV  ++G+YVK ADKLII+ LKE   L      KHSYPFCWRSDTPLL KAVPSWFI VE ++ +LL  N ETYWVP FVKE RF NWL+DARDWA+SRNR+WGTP+ LWVS+D EEVVCVGSIAELE LSG K+ DLHRES+DD+ IPS+  +GVL+RV EVFDCWFESGSMPYAQ H+PF  + K F + FPADFIAEGIDQTRGWFYTL V+ST +F K PFKNL+C+G+VLASDG KMSK  KNYPDP+ ++NKYGADALRLY+I+SPVVRG++L+F E GVRD++KD F+PWFN+++F F  ++  +E +  +    +F  N    + N+MD WI SFT SL+ F R +M  Y L  V   L K+ D LTN Y+R+NRKR++G+  +   +   A+  L  VL     +++PF PF  E+ +  LK+ +  +E              ESVH++M+P+ ++ LI   +E  V +M+ +++L R +RD++ LA+K PL E++++++D   ++ ++S+ESY+L ELNV+KLT+S DK+KY + L+AE N ++LG +LK + + V    K   TE +LE+F    K+T+LGHEL SE++ V     +D       Y++ S    I V++D  + + L++E + RE+ NR+QR RK+  L+  D   ++       V +  +S    +    L  I+    ++   PI   S      + T+ + S +KDS + +W   + +    D    +  S  V V         V+ +   +  + +LL HVR A + W       + L +V+   + P V  ++L GQ
Sbjct:  281 GSQLKDLRYEPLFPYFAYMREERNAFRVLNDTFVTSDSGTGVVHQAPYFGEIDFQVCVANGVIAKDQKMICPVDESGKYTSEVPDYQGVYVKDADKLIIKRLKEMGNLVRQAEVKHSYPFCWRSDTPLLYKAVPSWFINVETLIPRLLANNDETYWVPAFVKEKRFANWLRDARDWAVSRNRFWGTPINLWVSEDGEEVVCVGSIAELEELSGQKITDLHRESVDDVTIPSRSGRGVLKRVSEVFDCWFESGSMPYAQNHYPFE-NRKIFEDNFPADFIAEGIDQTRGWFYTLLVLSTALFNKPPFKNLICNGLVLASDGAKMSKSKKNYPDPMLIVNKYGADALRLYLINSPVVRGENLRFREEGVRDLLKDVFLPWFNAYRF-FVQNVQAYEHETGN----VFDMNVHVASENVMDRWIESFTNSLVAFVRKEMDSYRLYAVVGPLTKFFDTLTNIYIRLNRKRVKGD--NGLHEQHHALAALGRVLILIVRLMAPFTPFFCEYIWLNLKKVIGSTE--------------ESVHFLMLPKPDESLIDETVERRVEVMRNVIDLVRLVRDREGLAVKYPLKEMIVINRDSQFLEDVKSLESYILLELNVRKLTVSQDKQKYGITLKAEPNFKILGARLKGEQKKVADYLKNQITESELEKFLLEGKLTVLGHELSSEEVAVSYAAGSDQGHG---YKTHSDAKTI-VMIDTTEDESLIEEGLCREVTNRVQRLRKQAKLVSTDTAHVHI------VVSPADSQLAKVVAAKLNDIV----SATGTPIKLGSPPAAAKAPTATSKSAIKDSEVELWLFAEGDSF--DGITVVDGSKKVRVH--------VKTEKEHLKGYADLLYHVRSALDLWN----GKIALKNVDGSAVHPTVDVTSLVGQ 1135          

Query:   65 ISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEIVDRVASCNTKNTFRY 907
            I+FA EE  + + W +   F+  +E SK +  ++FYDGPPFATG+PHYGH+L  ++KD+V R+AHQ  H+VERRFGWD HG+P+EYEIDK L I GP DVMKMGI  YNNECR IVM+YS +WE  + RLGRW+DFK DYKT+YPWFMESVW+ F ++ +KGLVY+GVKVMPFSTACSTPLSNFEA QNYKDV DP+V V F L D  + +L+AWTTTPWTLPSNLAL V+PD+ YV  K+  TG  ++++E R+G + K++ +E+++++A    K+  RY
Sbjct:   11 INFAREEDKVAQKWQDENTFQRSVELSKDRPHFTFYDGPPFATGLPHYGHMLTSTIKDVVGRWAHQNGHYVERRFGWDTHGLPVEYEIDKTLGISGPQDVMKMGIANYNNECRKIVMRYSGEWEKTMGRLGRWVDFKHDYKTLYPWFMESVWWAFSELHKKGLVYKGVKVMPFSTACSTPLSNFEAGQNYKDVVDPAVFVGFKLLDCPNRQLVAWTTTPWTLPSNLALVVHPDMLYVVTKDKTTGIEYVVLEERLGEL-KNDNLEVIEKLAGSQLKD-LRY 289          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTE-QLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECS----ILSDTSGTSSEVKDSILSMWFTHDHNRLKTDNRKCLPKSSNVEVICDGDLNSVVQLDVMGIDSWDELLRHVRVAFE-WRRFAVAPVTLLDVNDKPIAP-VAPSTLKGQ 3564
            G +L+   Y PLF YF  M++E  AFR++ D++VT  SGTGVVHQAPYFGE D++VC++NG+I K   ++CPVDE GK+T+EV  ++G+YVK ADKLII+ LKE   L      KHSYPFCWRSDTPLL KAVPSWFI VE ++ +LL  N ETYWVP FVKE RF NWL+DARDWA+SRNR+WGTP+ LWVS+D EEVVCVGSIAELE LSG K+ DLHRES+DD+ IPS+  +GVL+RV EVFDCWFESGSMPYAQ H+PF  + K F + FPADFIAEGIDQTRGWFYTL V+ST +F K PFKNL+C+G+VLASDG KMSK  KNYPDP+ ++NKYGADALRLY+I+SPVVRG++L+F E GVRD++KD F+PWFN+++F F  ++  +E +  +    +F  N    + N+MD WI SFT SL+ F R +M  Y L  V   L K+ D LTN Y+R+NRKR++G+  +   +   A+  L  VL     +++PF PF  E+ +  LK+ +  +E              ESVH++M+P+ ++ LI   +E  V +M+ +++L R +RD++ LA+K PL E++++++D   ++ ++S+ESY+L ELNV+KLT+S DK+KY + L+AE N ++LG +LK + + V    K   TE +LE+F    K+T+LGHEL SE++ V     +D       Y++ S    I V++D  + + L++E + RE+ NR+QR RK+  L+  D   ++       V +  +S    +    L  I+    ++   PI   S      + T+ + S +KDS + +W   + +    D    +  S  V V         V+ +   +  + +LL HVR A + W       + L +V+   + P V  ++L GQ
Sbjct:  281 GSQLKDLRYEPLFPYFAYMREERNAFRVLNDTFVTSDSGTGVVHQAPYFGEIDFQVCVANGVIAKDQKMICPVDESGKYTSEVPDYQGVYVKDADKLIIKRLKEMGNLVRQAEVKHSYPFCWRSDTPLLYKAVPSWFINVETLIPRLLANNDETYWVPAFVKEKRFANWLRDARDWAVSRNRFWGTPINLWVSEDGEEVVCVGSIAELEELSGQKITDLHRESVDDVTIPSRSGRGVLKRVSEVFDCWFESGSMPYAQNHYPFE-NRKIFEDNFPADFIAEGIDQTRGWFYTLLVLSTALFNKPPFKNLICNGLVLASDGAKMSKSKKNYPDPMLIVNKYGADALRLYLINSPVVRGENLRFREEGVRDLLKDVFLPWFNAYRF-FVQNVQAYEHETGN----VFDMNVHVASENVMDRWIESFTNSLVAFVRKEMDSYRLYAVVGPLTKFFDTLTNIYIRLNRKRVKGD--NGLHEQHHALAALGRVLILIVRLMAPFTPFFCEYIWLNLKKVIGSTE--------------ESVHFLMLPKPDESLIDETVERRVEVMRNVIDLVRLVRDREGLAVKYPLKEMIVINRDSQFLEDVKSLESYILLELNVRKLTVSQDKQKYGITLKAEPNFKILGARLKGEQKKVADYLKNQITESELEKFLLEGKLTVLGHELSSEEVAVSYAAGSDQGHG---YKTHSDAKTI-VMIDTTEDESLIEEGLCREVTNRVQRLRKQAKLVSTDTAHVHI------VVSPADSQLAKVVAAKLNDIV----SATGTPIKLGSPPAAAKAPTATSKSAIKDSEVELWLFAEGDSF--DGITVVDGSKKVRVH--------VKTEKEHLKGYADLLYHVRSALDLWN----GKIALKNVDGSAVHPTVDVTSLVGQ 1135          

Query:   65 ISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEIVDRVASCNTKNTFRY 907
            I+FA EE  + + W +   F+  +E SK +  ++FYDGPPFATG+PHYGH+L  ++KD+V R+AHQ  H+VERRFGWD HG+P+EYEIDK L I GP DVMKMGI  YNNECR IVM+YS +WE  + RLGRW+DFK DYKT+YPWFMESVW+ F ++ +KGLVY+GVKVMPFSTACSTPLSNFEA QNYKDV DP+V V F L D  + +L+AWTTTPWTLPSNLAL V+PD+ YV  K+  TG  ++++E R+G + K++ +E+++++A    K+  RY
Sbjct:   11 INFAREEDKVAQKWQDENTFQRSVELSKDRPHFTFYDGPPFATGLPHYGHMLTSTIKDVVGRWAHQNGHYVERRFGWDTHGLPVEYEIDKTLGISGPQDVMKMGIANYNNECRKIVMRYSGEWEKTMGRLGRWVDFKHDYKTLYPWFMESVWWAFSELHKKGLVYKGVKVMPFSTACSTPLSNFEAGQNYKDVVDPAVFVGFKLLDCPNRQLVAWTTTPWTLPSNLALVVHPDMLYVVTKDKTTGIEYVVLEERLGEL-KNDNLEVIEKLAGSQLKD-LRY 289          

Query:  967 YVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTH-FEGIYVKTADKLIIQHLKEKKRLFNH-----GTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQL-LTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDD---YEEVVCVGSIAELERLSG-------VKVRDL--HRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVIN------KYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQ-LTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRL-----KQ--RLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVEL 2751
            +VT++ GTG+VH A   G  DY V +S G       +   VD  G +T  + H  +G       +++ +  K   RL NH         HSYP+ WR+  P++ ++   WFI V++I  +  +  +  +    D          +   + W ISR R WGTP+P  V D+   Y     +  +A+L R          + V+++  + E    + IPS +    L++  ++ D W +SG   +A      + D     E   AD + EG+DQ RGWF +L + S  +  K P+K ++  G  +  +  KMSK + N  DP  + +        GAD LR ++  S        K     + D+ K   I + N F+F+       F+ KQ            P KT   +D  ++    +++K      +++   TVA  L +++ +  +  YV+  R RL  + V S E  ISA  TL  + +    +ISP +P ++    Q L     KQ  RL F   +DL  G+       S H   + E    L      ES A        G KI   K          V+ V+ +  +I RI   ES + E LNV ++ L  ++ + +VEL
Sbjct:  369 HVTDTVGTGLVHTAFAHGFQDYDVAISKG-----DRVESFVDSRGCYTRHLGHDLDG------KEVLGEGQKIALRLLNHDIVHVSKHVHSYPYDWRTKKPVIIRSSEQWFIDVDEIGKRASMMLDDISVAAGDSDLRASLKQLVTTRKSWCISRQRVWGTPIPALVDDNGGSYTSRKLIEWVAKLTRERENTDVWWEIDVKEILENEEVRRSLEIPSDI-VSQLKKNTDIMDVWLDSGLAWHA------ARDNDTERE-HVADVVLEGVDQFRGWFQSLLLTSVAVQNKLPYKKIIVHGFCIDENNNKMSKSIGNVVDPTMLTDGSLKQKAIGADGLRFWVALSGSENAGESKIGMKIIDDVDKK-VIAFRNGFRFMI-GGCQGFDGKQ---------VKFPLKT---LDIDMLQNCDAIVKRSIVNYNDFKFRTVANDLTQFLQRNFSANYVKYVRDRLYCDKVGS-ESHISAQFTLHRLAHNLAHIISPILPHLSSEVLQHLPGSHEKQILRLKF---EDLHYGLLTPHDQLSKHMKFVYEVRNLL------ESTA--------GPKIDTSKKGI-------VLQVTPEYHTILRI--YESELPELLNVSQVILHENRDENSVEL 936          

Query:  146 KHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYK 637
            K  + +   DGPP+A G  H GH +   +KD V +      + V  R GWDCHG+PIE +I K+    G    ++    A     R +  +      +   R G   D++K Y T  P ++ +   IF ++ E+ LVYR  K + +S + +T L+  E + N K
Sbjct:   84 KDSEIFELLDGPPYANGEAHTGHAINKILKDFVVKSRIALGYRVLFRPGWDCHGLPIELKIGKQQGNAGSRTPLETRAAA-----RIVADEAIGKQMNAFRRWGVTADWEKPYVTKSPSYVAAQLDIFAKLVEQKLVYRSFKPVYWSPSSNTALAESELEYNDK 242          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTA--NAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLW---VSDDYE-----EVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHS--------------------------SLVPFEKKQNSGRPL---LFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKY-IDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSE 2427
            I  DS+V    GTG V   P    +DY V    GI +      C  D+ G  +     F G+    A   +I+ LKEK             P C RS   +     P W+++   + ++ + A  N +   +P+F K   +  WL+ +RDW ISR  +WG  +P +    +D  E     E   V +  E E L+         ++     +P    + +L+   +V D WF SG  P+A   +P +T  K  +  FP   +  G D    W   +  ++  + GK PFK ++   ++  + G+KMSK L N  DPL+VI     + L+  ++   +   +     E   RD          ++ +F   S                           +V F   + S +P     F+ N   K+    D WI+S     +K     +  Y+          + +    + YV   +  L G+  +  +  IS +H     +     +ISP +PFI+E  +QR+  RLD S+
Sbjct:  357 IFADSFVEMEFGTGAVKITPAHDHNDYEV----GIRQNLPFHNCITDD-GLISQGCGEFSGMKRFDARTAVIEALKEKGLYRGKEDNPMVVPTCSRSKDVIEPILKPQWYVKCAHMAEKAVAAVANGDLQIIPEFHKAT-WNRWLESSRDWCISRQLWWGHRIPAYYISFADGREQPLPEENYWVSARTEQEALA---------KAAQKFQVPEA--EILLKWDEDVLDTWFSSGMWPFAVFGWPDAT--KDMDLFFPGAVLETGHDILFFWVARMVFMAQELTGKLPFKEILLHAMIRDAHGRKMSKSLGNVIDPLDVIRGISLNDLQAQLLGGNLDEKEIAVAKEGQARDYPDGIPECGVDALRFALLSYTSQGRDINLDVLRVHGYRKFCNKLWQVVRFALARISDKPEQKPTFEINL--KSATPTDLWILSRLAKAVKETNEALKAYNFTQATTVTYNFWLYDFCDVYVETIKPVLYGDNTTLRQVAISVLHK---CIDTGLRLISPLMPFISEELWQRMP-RLDDSD 863          

Query:  179 PPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIV----SRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFE 619
            PP  TG  H GH LA +++D +TRF            G D  G+  +  ++K+L  +       +G   +N E    V  +  +  D++     +LG  +D+ +   TM P    +V   F ++ E G +YR  +++ +S A  + +S+ E
Sbjct:  126 PPNVTGNLHVGHALATTVEDTITRFNRMHGKRTLFNPGCDHAGIATQVVVEKRLKRERGLTRHDLGRDRFNQE----VWHWKNEKGDVIYDQFRKLGASVDWDRAVFTMDPKMCRAVTEAFIRMHESGTIYRSNRLVNWSCALRSAISDIE 272          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTA--NAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLW---VSDDYE-----EVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHS--------------------------SLVPFEKKQNSGRPL---LFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKY-IDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSE 2427
            I  DS+V    GTG V   P    +DY V    GI +      C  D+ G  +     F G+    A   +I+ LKEK             P C RS   +     P W+++   + ++ + A  N +   +P+F K   +  WL+ +RDW ISR  +WG  +P +    +D  E     E   V +  E E L+         ++     +P    + +L+   +V D WF SG  P+A   +P +T  K  +  FP   +  G D    W   +  ++  + GK PFK ++   ++  + G+KMSK L N  DPL+VI     + L+  ++   +   +     E   RD          ++ +F   S                           +V F   + S +P     F+ N   K+    D WI+S     +K     +  Y+          + +    + YV   +  L G+  +  +  IS +H     +     +ISP +PFI+E  +QR+  RLD S+
Sbjct:  357 IFADSFVEMEFGTGAVKITPAHDHNDYEV----GIRQNLPFHNCITDD-GLISQGCGEFSGMKRFDARTAVIEALKEKGLYRGKEDNPMVVPTCSRSKDVIEPILKPQWYVKCAHMAEKAVAAVANGDLQIIPEFHKAT-WNRWLESSRDWCISRQLWWGHRIPAYYISFADGREQPLPEENYWVSARTEQEALA---------KAAQKFQVPEA--EILLKWDEDVLDTWFSSGMWPFAVFGWPDAT--KDMDLFFPGAVLETGHDILFFWVARMVFMAQELTGKLPFKEILLHAMIRDAHGRKMSKSLGNVIDPLDVIRGISLNDLQAQLLGGNLDEKEIAVAKEGQARDYPDGIPECGVDALRFALLSYTSQGRDINLDVLRVHGYRKFCNKLWQVVRFALARISDKPEQKPTFEINL--KSATPTDLWILSRLAKAVKETNEALKAYNFTQATTVTYNFWLYDFCDVYVETIKPVLYGDNTTLRQVAISVLHK---CIDTGLRLISPLMPFISEELWQRMP-RLDDSD 863          

Query:  179 PPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIV----SRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFE 619
            PP  TG  H GH LA +++D +TRF            G D  G+  +  ++K+L  +       +G   +N E    V  +  +  D++     +LG  +D+ +   TM P    +V   F ++ E G +YR  +++ +S A  + +S+ E
Sbjct:  126 PPNVTGNLHVGHALATTVEDTITRFNRMHGKRTLFNPGCDHAGIATQVVVEKRLKRERGLTRHDLGRDRFNQE----VWHWKNEKGDVIYDQFRKLGASVDWDRAVFTMDPKMCRAVTEAFIRMHESGTIYRSNRLVNWSCALRSAISDIE 272          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKM-NKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNM-----MDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIY--CWSESESVRAVFESHAEM 3171
            G+ L+   Y PLF YF K   E  A+R++ D YVTE SGTG+VH APYFGEDDYRVCL+ G+I K+  ++CPVDE G+FTNE + FEG YVK +DK I+  LK +  L + G  KHSYPFCWRSDTPL+ KAVPSWF+RVE +   LL  +++TYWVPDFVKE RF NWLK+ARDWAISRNRYWGTP+P+W S   +E V +GSI +L  LSGV+V DLHRESID I IPS +     LRR+  VFDCWFESGSMP+AQ HFPF  + K F   FPADFIAEGIDQTRGWFYTL VIST +F KAPFKNL+ SG+VLA+DGQKMSKR KNYPDP+EV++KYGADALRLY+I+SPVVR +SL+F E GVRD+IKD F+PW+N+++FL   ++V +EK+  +G    +  +      NM     +D WI+SF +SL++FF  +M  Y L TV PRL K+IDQLTNWYVR+NR+R++GE+    +  I ++ TL+ VLY    M++PF P++TE+ +QRL   + F     L+         +SVHY M+P   K  I+ DIE SVALMQ++VELGR +RD++TL +K P+ E++ + +D   ++ I++++ ++L ELNV+KLTLS+DK+KY V LRAE +H+ LG +LK +++AV+ A K L  +++++  +     IL   +  +++ +I      ++     +E+ S  + +LVL+D   ++ELL+E +ARE+INR+Q+ +K+  LIP DPV I+    +++++ + V E+ A++
Sbjct:  289 GKTLKDLHYKPLFPYFAKRGAEVKAYRVLVDEYVTEDSGTGIVHNAPYFGEDDYRVCLAAGLITKSSEVLCPVDEAGRFTNEASDFEGQYVKDSDKQIMAALKARGNLVSSGQVKHSYPFCWRSDTPLIYKAVPSWFVRVEHMSKNLLDCSSQTYWVPDFVKEKRFGNWLKEARDWAISRNRYWGTPIPIWRSPSGDETVVIGSIKQLAELSGVQVEDLHRESIDHIEIPSAVPGNPPLRRIAPVFDCWFESGSMPFAQQHFPFENE-KDFMNNFPADFIAEGIDQTRGWFYTLLVISTALFNKAPFKNLIASGLVLAADGQKMSKRKKNYPDPMEVVHKYGADALRLYLINSPVVRAESLRFKEEGVRDIIKDVFLPWYNAYRFLLQ-NIVRYEKEDLAGNG-QYTYDRERHLKNMDKASVIDVWILSFKESLLEFFATEMKMYRLYTVVPRLTKFIDQLTNWYVRLNRRRIKGEL--GADQCIQSLDTLYDVLYTMVKMMAPFTPYLTEYIFQRL---VLFQPAGTLEHA-------DSVHYQMMPVSQKKFIRNDIERSVALMQSVVELGRVMRDRRTLPVKYPVSEIIAIHKDSQILEAIKTLQDFILSELNVRKLTLSSDKEKYGVTLRAEPDHKALGQRLKGNFKAVMAAIKALRDDEIQKQVSQGYFDILDQRIELDEVRIIYCT---SEQVGGNFEAHSD-NEVLVLLDMTPNEELLEEGLAREVINRVQKLKKKAQLIPTDPVLIFHELAADNKAKQEVLEAQAQL 1044          

Query:   59 EAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS 847
            E I+F  EE+ +L+ W     FE C + SK K KY+FYDGPPFATG+PHYGH+LAG++KDIVTR+A+Q  +HV+RRFGWDCHG+P+E+EIDK LNI+GP DV KMGI AYN ECR IVM+Y+ +WE++V+R+GRWIDFK DYKT+YPW+MES+W+IFKQ+F+KGLVY+GVKVMP+STAC+T LSNFEA QNYK+V DP V+V        +T  L WTTTPWTLPSN A CV+P + YVKV++VK+ +LF++ ESR+ YV+KS
Sbjct:   15 ENINFPAEEENVLQKWRHENIFEKCSQLSKGKPKYTFYDGPPFATGLPHYGHILAGTIKDIVTRYAYQQGYHVDRRFGWDCHGLPVEFEIDKLLNIKGPEDVAKMGIAAYNAECRKIVMRYADEWENVVTRVGRWIDFKNDYKTLYPWYMESIWWIFKQLFDKGLVYQGVKVMPYSTACTTSLSNFEANQNYKEVVDPCVVVALEAVSLPNTFFLVWTTTPWTLPSNFACCVHPTMTYVKVRDVKSDRLFVLAESRLSYVYKS 277          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKM-NKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNM-----MDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIY--CWSESESVRAVFESHAEM 3171
            G+ L+   Y PLF YF K   E  A+R++ D YVTE SGTG+VH APYFGEDDYRVCL+ G+I K+  ++CPVDE G+FTNE + FEG YVK +DK I+  LK +  L + G  KHSYPFCWRSDTPL+ KAVPSWF+RVE +   LL  +++TYWVPDFVKE RF NWLK+ARDWAISRNRYWGTP+P+W S   +E V +GSI +L  LSGV+V DLHRESID I IPS +     LRR+  VFDCWFESGSMP+AQ HFPF  + K F   FPADFIAEGIDQTRGWFYTL VIST +F KAPFKNL+ SG+VLA+DGQKMSKR KNYPDP+EV++KYGADALRLY+I+SPVVR +SL+F E GVRD+IKD F+PW+N+++FL   ++V +EK+  +G    +  +      NM     +D WI+SF +SL++FF  +M  Y L TV PRL K+IDQLTNWYVR+NR+R++GE+    +  I ++ TL+ VLY    M++PF P++TE+ +QRL   + F     L+         +SVHY M+P   K  I+ DIE SVALMQ++VELGR +RD++TL +K P+ E++ + +D   ++ I++++ ++L ELNV+KLTLS+DK+KY V LRAE +H+ LG +LK +++AV+ A K L  +++++  +     IL   +  +++ +I      ++     +E+ S  + +LVL+D   ++ELL+E +ARE+INR+Q+ +K+  LIP DPV I+    +++++ + V E+ A++
Sbjct:  289 GKTLKDLHYKPLFPYFAKRGAEVKAYRVLVDEYVTEDSGTGIVHNAPYFGEDDYRVCLAAGLITKSSEVLCPVDEAGRFTNEASDFEGQYVKDSDKQIMAALKARGNLVSSGQVKHSYPFCWRSDTPLIYKAVPSWFVRVEHMSKNLLDCSSQTYWVPDFVKEKRFGNWLKEARDWAISRNRYWGTPIPIWRSPSGDETVVIGSIKQLAELSGVQVEDLHRESIDHIEIPSAVPGNPPLRRIAPVFDCWFESGSMPFAQQHFPFENE-KDFMNNFPADFIAEGIDQTRGWFYTLLVISTALFNKAPFKNLIASGLVLAADGQKMSKRKKNYPDPMEVVHKYGADALRLYLINSPVVRAESLRFKEEGVRDIIKDVFLPWYNAYRFLLQ-NIVRYEKEDLAGNG-QYTYDRERHLKNMDKASVIDVWILSFKESLLEFFATEMKMYRLYTVVPRLTKFIDQLTNWYVRLNRRRIKGEL--GADQCIQSLDTLYDVLYTMVKMMAPFTPYLTEYIFQRL---VLFQPAGTLEHA-------DSVHYQMMPVSQKKFIRNDIERSVALMQSVVELGRVMRDRRTLPVKYPVSEIIAIHKDSQILEAIKTLQDFILSELNVRKLTLSSDKEKYGVTLRAEPDHKALGQRLKGNFKAVMAAIKALRDDEIQKQVSQGYFDILDQRIELDEVRIIYCT---SEQVGGNFEAHSD-NEVLVLLDMTPNEELLEEGLAREVINRVQKLKKKAQLIPTDPVLIFHELAADNKAKQEVLEAQAQL 1044          

Query:   59 EAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS 847
            E I+F  EE+ +L+ W     FE C + SK K KY+FYDGPPFATG+PHYGH+LAG++KDIVTR+A+Q  +HV+RRFGWDCHG+P+E+EIDK LNI+GP DV KMGI AYN ECR IVM+Y+ +WE++V+R+GRWIDFK DYKT+YPW+MES+W+IFKQ+F+KGLVY+GVKVMP+STAC+T LSNFEA QNYK+V DP V+V        +T  L WTTTPWTLPSN A CV+P + YVKV++VK+ +LF++ ESR+ YV+KS
Sbjct:   15 ENINFPAEEENVLQKWRHENIFEKCSQLSKGKPKYTFYDGPPFATGLPHYGHILAGTIKDIVTRYAYQQGYHVDRRFGWDCHGLPVEFEIDKLLNIKGPEDVAKMGIAAYNAECRKIVMRYADEWENVVTRVGRWIDFKNDYKTLYPWYMESIWWIFKQLFDKGLVYQGVKVMPYSTACTTSLSNFEANQNYKEVVDPCVVVALEAVSLPNTFFLVWTTTPWTLPSNFACCVHPTMTYVKVRDVKSDRLFVLAESRLSYVYKS 277          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKM-NKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNM-----MDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIY--CWSESESVRAVFESHAEM 3171
            G+ L+   Y PLF YF K   E  A+R++ D YVTE SGTG+VH APYFGEDDYRVCL+ G+I K+  ++CPVDE G+FTNE + FEG YVK +DK I+  LK +  L + G  KHSYPFCWRSDTPL+ KAVPSWF+RVE +   LL  +++TYWVPDFVKE RF NWLK+ARDWAISRNRYWGTP+P+W S   +E V +GSI +L  LSGV+V DLHRESID I IPS +     LRR+  VFDCWFESGSMP+AQ HFPF  + K F   FPADFIAEGIDQTRGWFYTL VIST +F KAPFKNL+ SG+VLA+DGQKMSKR KNYPDP+EV++KYGADALRLY+I+SPVVR +SL+F E GVRD+IKD F+PW+N+++FL   ++V +EK+  +G    +  +      NM     +D WI+SF +SL++FF  +M  Y L TV PRL K+IDQLTNWYVR+NR+R++GE+    +  I ++ TL+ VLY    M++PF P++TE+ +QRL   + F     L+         +SVHY M+P   K  I+ DIE SVALMQ++VELGR +RD++TL +K P+ E++ + +D   ++ I++++ ++L ELNV+KLTLS+DK+KY V LRAE +H+ LG +LK +++AV+ A K L  +++++  +     IL   +  +++ +I      ++     +E+ S  + +LVL+D   ++ELL+E +ARE+INR+Q+ +K+  LIP DPV I+    +++++ + V E+ A++
Sbjct:  289 GKTLKDLHYKPLFPYFAKRGAEVKAYRVLVDEYVTEDSGTGIVHNAPYFGEDDYRVCLAAGLITKSSEVLCPVDEAGRFTNEASDFEGQYVKDSDKQIMAALKARGNLVSSGQVKHSYPFCWRSDTPLIYKAVPSWFVRVEHMSKNLLDCSSQTYWVPDFVKEKRFGNWLKEARDWAISRNRYWGTPIPIWRSPSGDETVVIGSIKQLAELSGVQVEDLHRESIDHIEIPSAVPGNPPLRRIAPVFDCWFESGSMPFAQQHFPFENE-KDFMNNFPADFIAEGIDQTRGWFYTLLVISTALFNKAPFKNLIASGLVLAADGQKMSKRKKNYPDPMEVVHKYGADALRLYLINSPVVRAESLRFKEEGVRDIIKDVFLPWYNAYRFLLQ-NIVRYEKEDLAGNG-QYTYDRERHLKNMDKASVIDVWILSFKESLLEFFATEMKMYRLYTVVPRLTKFIDQLTNWYVRLNRRRIKGEL--GADQCIQSLDTLYDVLYTMVKMMAPFTPYLTEYIFQRL---VLFQPAGTLEHA-------DSVHYQMMPVSQKKFIRNDIERSVALMQSVVELGRVMRDRRTLPVKYPVSEIIAIHKDSQILEAIKTLQDFILSELNVRKLTLSSDKEKYGVTLRAEPDHKALGQRLKGNFKAVMAAIKALRDDEIQKQVSQGYFDILDQRIELDEVRIIYCT---SEQVGGNFEAHSD-NEVLVLLDMTPNEELLEEGLAREVINRVQKLKKKAQLIPTDPVLIFHELAADNKAKQEVLEAQAQL 1044          

Query:   59 EAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS 847
            E I+F  EE+ +L+ W     FE C + SK K KY+FYDGPPFATG+PHYGH+LAG++KDIVTR+A+Q  +HV+RRFGWDCHG+P+E+EIDK LNI+GP DV KMGI AYN ECR IVM+Y+ +WE++V+R+GRWIDFK DYKT+YPW+MES+W+IFKQ+F+KGLVY+GVKVMP+STAC+T LSNFEA QNYK+V DP V+V        +T  L WTTTPWTLPSN A CV+P + YVKV++VK+ +LF++ ESR+ YV+KS
Sbjct:   15 ENINFPAEEENVLQKWRHENIFEKCSQLSKGKPKYTFYDGPPFATGLPHYGHILAGTIKDIVTRYAYQQGYHVDRRFGWDCHGLPVEFEIDKLLNIKGPEDVAKMGIAAYNAECRKIVMRYADEWENVVTRVGRWIDFKNDYKTLYPWYMESIWWIFKQLFDKGLVYQGVKVMPYSTACTTSLSNFEANQNYKEVVDPCVVVALEAVSLPNTFFLVWTTTPWTLPSNFACCVHPTMTYVKVRDVKSDRLFVLAESRLSYVYKS 277          

Query:  964 SYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHF-EGIYV-KTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVE-------DIVDQLLT---ANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAE----LERLSG------VK----------VRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQ---SLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYI-DQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITE 2385
            S+V +S GTG+VH AP  G +D+ V L+  I      + C V+E G +T E   F  G  V    + L++  + E   + +    +HSYP  WR+  P++ +A   WFI  E       D ++Q+     ANAE         +      L+    W ISR R WG P+P+  S +  +VV   ++ E    L R  G      VK          +R+LH E+ D            L +  ++ D WF+SGS   A +            +   AD   EG DQ  GWF +  ++S      AP+K L   G  +   G KMSK L N   P ++  KYG DALR ++ S          S K ++    ++ K        + ++L     V  EK+  SG  L+ + +     N  +   ++ F   + K ++     Y  + V   +  +I +Q++  YV + + RL       + + ++   TL     Q    + P VPF+ E
Sbjct:  344 SHVQDSKGTGLVHTAPAHGPEDFLVSLTQKI-----PVKCFVNEEGTYTKEAPDFLRGKSVLDQGNSLVLDRIAED--VVHSSKLEHSYPIDWRTKKPVIIRASEQWFINTEKLKTPAADALEQVEIYPRANAE-------ASKKALLTQLQKRPYWCISRQRAWGVPIPVLYSRESGKVVLNSALIEHLCNLLRKEGSIDFWWVKSVEELVPEHLLRELHHEAKD------------LVKGTDILDIWFDSGSTWSAVL-----------GKDKIADLYLEGYDQFTGWFQSSLLMSIAARECAPYKALFVHGFTVDEKGYKMSKSLGNVISPKQITKKYGTDALRWWVASHGTQHMSITVSDKLLQQAAENLCK-----IRGTMRYL---KGVIGEKQ--SGEKLI-RTSDKSYLNRYLLSQLVEFESEVEKLYQA----YEYNRVVACVQNFIANQVSAVYVHLIKDRL---YCGDDHELLAIRQTLTHCYQQLCKSLWPIVPFLVE 798          

Query:   29 IKLDMSEFFNEAISFADEEKLILKYWNEIKAFETCLEQ---SKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKD--YKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLR------DDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVK-EVKTGKLFIIMESRIGYVFKSN---QVEIVDRVA 877
            I L  ++F N   +   EE+  L   N+I       EQ    K K  +  +DGPP+A G  H GH +   +KDI  R        V    GWDCHG+PIE +       Q   ++ +        + R+   +  +  ++  S  G   +++KD  Y T  P F+ +   +F  ++EKGLVYR +K + +S +  T L+  E + +   ++ PSV V F L        D     L WTTTPWTLPSN A+C N  L+YV V+   +      +M S +   F++N   + EIV  ++
Sbjct:   30 INLPKTKFPNRLTAAKREEQERLVLENKIAVSYAYQEQRLAEKGKPTFVLHDGPPYANGQLHMGHAVNKILKDITLRQRVAHGQRVNYIPGWDCHGLPIELKATSTAPGQSAQEIRQ--------KSRAFAWEAIKSQKEEFSSWGILANWQKDNIYMTFQPEFIVNQLEMFYNLYEKGLVYRDLKPVYWSPSSRTALAEAELEYDANHIS-PSVYVRFALNPSSFDVKDKQIYALVWTTTPWTLPSNQAICYNASLEYVIVRLSDRNQDELYLMASALMADFEANTQLKCEIVQHLS 318          

Query:  883 QYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTA--NAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLP----------LWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISS----------------------PVVRGQSLKFVESG----VRDMIKD---------FFIPWFNSFKF--LFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKY-IDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRL 2403
            Q   Y  L   F+     T    I+CD +V  + GTG V   P    +DY V     +       +   ++ G    +   F G+      K I++ LK               P C RS   +     P W++   D+      A  + E   +P+   +  + +W+   RDW +SR  +WG  +P          L    + +E   + + +E E L+    +   R  +D        +K VL++  +V D WF SG  P++   +P  T  K     +P   +  G D    W   +      + GK PFK +    +V  + G+KMSK L N  DP++VI     + L   ++ S                      P     +L+F         RD+  D         F    +N+ KF  L+ +    F+ + ++   +           N MD WI+S   + I+        Y           + +  L + Y+   +   +     S E   +A  TL+  L     ++SPF+PFITE  YQRL
Sbjct:  344 QDDRYKHLHGKFVVHPFSTRRLPIVCDEFVDMAFGTGAVKITPAHDPNDYEVGKRCNL-----PFITIFNDDGYIIGDYGEFTGMKRFECRKKILEKLKALNLYRETLNNPMVVPICSRSKDVVEPLIKPQWYVSCSDMAASATEAVRSGELKIIPEHHTKTWY-HWMDGIRDWCVSRQLWWGHRIPAYHVSFTDPSLQTGSNDDEQYWIVARSEAEALT----KAAERFGVD-------ASKIVLKQDEDVLDTWFSSGIFPFSVFGWPDQT--KDLQTFYPTSLLETGHDILFFWVARMVFFGQKLLGKLPFKEVYLHPMVRDAHGRKMSKSLGNVIDPMDVIRGITLEGLHAQLVGSNLDPREIEKAKAGQKQDYPQGIPECGSDALRFALCAYITQARDINLDINRVLGYRFFCNKLWNATKFALLYFTGSEKFDTELSASAAI-----------NQMDAWILSRLAAAIEACNTGFESYDFAAATSACYAFWLYDLCDVYLECLKPIFQS---GSEEQQTAARRTLYVCLDYGLRLLSPFMPFITEELYQRL 867          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIY--CWSESESVRAVFESHAEMIYRTILQPI 3198
            G+ L+ K+Y PLFEYFIK K ETGAF ++ D+YV +  GTGVVHQAPYFG DDYRVC+   II++    +CPVD  G FT EVTHF G YVK ADK II+ LKE  RL +  + KHSYPFCWRSDTPL+ KAVPSWFIRVE +V++LL  N++ YWVP+FVKE RF NWL+DARDWA+SRNRYWGTP+PLWVSDD+EEVVCVGS+AELE L+G+KV DLHRESID + IPS+  KG LRRV EVFDCWFESGSMPYAQVH+PF  + ++F + FPADFIAEGIDQTRGWFYTL V+ST +FGK PFKN++ +G+VLASDGQKMSKR KNYPDP  ++  YGADALRLY+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL  +       ++  G   L+   T   +NN+MD+WI SFTQSLI+FFR +M  Y L TV P+L+K++D LTNWYVRMNR+RL+GE  S +ED + A+ TLF VL+    +++PF PFITE  YQ L+  LD + +++   G        S+HY+M+P+  + LI   IE +V+ MQ+++ELGR IRD+KTL +K PL EVV++ QD +++  I+S+++Y+LEELNV++LTLS DK +Y + LRAE +H +LG +LK  +++V  + K L +E+LEEFQ T  I + GH+L  EDL ++ T +  + +   QYE+ S    +LVL+D      +L E VARE+INRIQ+ RK+ +L+P D +T++  C    E +  V  +H + I  T   P+
Sbjct:  281 GKTLKGKKYKPLFEYFIKCK-ETGAFSVVMDNYVRDDDGTGVVHQAPYFGADDYRVCMEYDIIQRDSAPICPVDPSGIFTPEVTHFAGQYVKDADKNIIKWLKENGRLVSASSFKHSYPFCWRSDTPLIYKAVPSWFIRVEHMVEKLLDNNSKCYWVPEFVKEKRFGNWLRDARDWAVSRNRYWGTPIPLWVSDDFEEVVCVGSMAELEELTGIKVTDLHRESIDGLTIPSRCGKGQLRRVSEVFDCWFESGSMPYAQVHYPFE-NRREFEDAFPADFIAEGIDQTRGWFYTLLVLSTALFGKPPFKNVIVNGLVLASDGQKMSKRKKNYPDPGLIVQSYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVFLPWYNAYRFLVQNVQ---RLQKEEGVEFLYNERTSSVSNNIMDKWIQSFTQSLIQFFRDEMGAYRLYTVVPKLVKFVDMLTNWYVRMNRRRLKGE--SGSEDCVRALETLFSVLFSMCRLMAPFTPFITELMYQNLRHLLDPAAVEEKDTG--------SIHYLMLPQVRESLIDQRIESAVSRMQSVIELGRVIRDRKTLPIKYPLKEVVVIHQDPEALTDIQSLQNYILEELNVRQLTLSTDKDRYGIRLRAEPDHMVLGKRLKGAFKSVTASIKELKSEELEEFQKTGCIVVDGHDLREEDLRLMYTFDQSSGSAS-QYEAHSDAQ-VLVLLDVTPDQAMLDEGVAREVINRIQKLRKKGHLVPSDEITVFYRCQPAGEYLHQVI-AHTDFILATTKAPL 1040          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSN 850
            M E   E+I F  EE+ IL++W +   F+ CL+QSK + +++FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ   HVERRFGWDCHG+P+EYEIDK LNI+GP DVMKMGI  YN +CRSIVM+Y+ +WE+ V R+GRWIDF+ DYKT+YPWFME+VW++FKQ+++ GLVYRGVKVMPFSTAC+TPLSNFEA QNYKDV DPSVIV FPL +D S  L+AWTTTPWTLPSNLALCVNP+L YV+VK+  + K++I+ME+R+  +FKS+
Sbjct:    1 MVEAVPESIHFPTEEEQILQFWQKNDCFQECLKQSKSRPRFTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQNGFHVERRFGWDCHGLPVEYEIDKSLNIKGPEDVMKMGIEEYNKQCRSIVMRYADEWENSVRRMGRWIDFRNDYKTLYPWFMETVWWVFKQLYDSGLVYRGVKVMPFSTACNTPLSNFEANQNYKDVQDPSVIVNFPLLEDPSVSLIAWTTTPWTLPSNLALCVNPELIYVRVKDNSSQKIYIMMEARLVALFKSD 270          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFE---GIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARD-WAISRNRYWGTPLPLWVSDDY-EEVVCVGSIAELERLSGVKVRD-LHRESIDDIIIPSKMNKGVLRRVPE------VFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINK---------YGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYID--QLTNWYVRMNRKRLRGEIVSSNEDWI---SAIHTLFFVLYQATVMISPFVPFITEFFY 2394
            ++  S+VT + GTG+VH AP  G DDY V     +      + C VDE G+FT E+   E      +   +  +I  L+    +       HSYP+ WR+  P++ +A   WFI    + D+   A  +   +P+  + +  +  + D R  W ISR R WG P+P++   +  E ++   ++  + ++   K  D    E ++  + P  + K     V +      V D WF+SG+  +A V  P S           AD   EG DQ  GWF +  + S  +  KAP+K LV  G  ++  G+KMSK + N  DP  VIN          YGAD LR ++  S V    S   +     +  KD      N+ KFL   +L  F+ +  +           PK  + +D++++   +          SE++   V  RL++     +L+N+Y  + + RL        ED +   S    L  +L   +  I+P +P + E  Y
Sbjct:  345 LLPASHVTMTKGTGLVHTAPAHGMDDYSVATHFNL-----PVECMVDEEGRFT-ELAGAELQNKSVMDEGNAAVISVLQAAGAVVKEEDCVHSYPYDWRTKQPVVIRASRQWFINTATLKDKAKDALQKVRVIPESARSSLLS--MLDRRTYWCISRQRSWGVPIPVFYHKETGEPLLNKHTVTHIAKVFSEKGSDSWWTEPVETFLTPDVLQKSKASSVSDYVRGEDVLDIWFDSGAS-WAAV-LPESDPR--------ADSYVEGKDQIGGWFQSSLLTSVAVRNKAPYKALVVHGFAVSEKGEKMSKSIGNVVDPDVVINGGKDSSVSPPYGADVLRWWVAESNVF---SEVQIGPNALNAAKDSINKLRNTLKFLL-GNLQGFDPRSQA---------VDPKQMHYIDQYMLHLLREFSMKVTDAYSEFNYGLVI-RLLQSFTARELSNFYFSIIKDRL----YCDPEDSVGRRSCQTVLEEILDGVSRSIAPVLPHLAEEVY 815          

Query:  140 QSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPL-----------RDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRI 829
            + K KK+Y  +DGPP+A G PH GH L   +KDI  RF       V    GWDCHG+PIE    K L   G  ++  + I     + R    K          R G   D+   Y T    +  +   +F+++  KGL+Y+  K + +S +  T L+  E + N + V+  S+ +TFPL              S+   L WTT PWT+P+N A+C  P + Y  VK   T +L ++   RI
Sbjct:   73 EKKAKKEYCLHDGPPYANGDPHVGHALNKILKDIRNRFEVLRGRQVHYVPGWDCHGLPIEL---KALGDLGTNELTPVQI---RQKAREFAEKAISRQRAAFQRWGVMADWDNCYYTFDGKYEAAQLKVFQEMHNKGLIYQDYKPVFWSPSSRTALAEAELEYNPEHVSR-SLYITFPLLTLPAKLTAKAEGLSNVSALIWTTQPWTIPANQAVCYMPKVQYSVVKRADTEQLLLVATERI 306          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNG-----IIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSD---TPLLNKAVPSWFIRVEDIVDQLLTA--NAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLW-------VSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFE-----------------KKQNSGRPLLFKPN-----TPPKTN---NMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKY-IDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQAT----VMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIR 2583
            I+ D+ V  + GTG V   P     D+ +   +      +I   GT+      CG++   V  F+      A + +I  L E+K          S P C RS     PLL K    WF+R +++  + + A    +   +P F  +  + +WL +  DW +SR  +WG  +P +       ++ + E  V   S AE ++ + +K   ++ E+I             L + P+V D WF SG  P+A + +P  T  K   + +P   +  G D    W   + ++ T + G+ PFK ++   +V    G+KMSK L N  DPL+VI+    + L+  +    +   +S+  +E+  +D  K       ++ +F   S     E                 K   + R  L   N     TP       + MD+WI S   S +K        Y L TV   L  + +  L + Y+   +  L+ E     E+ +        VLY +      ++SPF+PF+TE  +QRL     F          D   C   VH        +    P  E   +L+Q +V + R +R
Sbjct:  362 IVTDTTVDMTFGTGAVKLTPAHDHTDFLLSQKHSLPRLTVIGGNGTMT---SVCGQWLEGVKRFD------ARERVISALMERKLFRGKKDHPMSLPICSRSGDVIEPLLKK---QWFVRCQEMAKKAVQAVEEGDLQIIPQFYSK-MWKSWLSNISDWCVSRQLWWGHQIPAYRVTLQNSMNTEEEHWVWGRSAAEAQQRATIKF-GVNPEAI------------TLTQDPDVLDTWFSSGLFPFAMLGWPQQT--KDLTQFYPNSILETGSDLIFFWVARMVMLGTELTGQLPFKQVLFHSLVRDKYGRKMSKSLGNVIDPLDVISGVSLERLQEKVKEGNLDPRESIVAIEAQKKDFPKGIPECGTDALRFALCSYRAQGEDISLSMSHVLSCRHFCNKMWQTVRFTLATLNDASLPTPLAETYPLSSMDKWICSRLYSTVKECEQGFESYELHTVTSALHSFWLHCLCDVYLESIKPLLKPE---GCEERVGERQVATSVLYHSVSVSLALLSPFMPFLTEELWQRLLPYGHF----------DKTSCSLCVHPYPKTSQLEHWYFPKEEADFSLVQEVVRVTRLLR 911          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNG-----IIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSD---TPLLNKAVPSWFIRVEDIVDQLLTA--NAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLW-------VSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFE-----------------KKQNSGRPLLFKPN-----TPPKTN---NMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKY-IDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQAT----VMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIR 2583
            I+ D+ V  + GTG V   P     D+ +   +      +I   GT+      CG++   V  F+      A + +I  L E+K          S P C RS     PLL K    WF+R +++  + + A    +   +P F  +  + +WL +  DW +SR  +WG  +P +       ++ + E  V   S AE ++ + +K   ++ E+I             L + P+V D WF SG  P+A + +P  T  K   + +P   +  G D    W   + ++ T + G+ PFK ++   +V    G+KMSK L N  DPL+VI+    + L+  +    +   +S+  +E+  +D  K       ++ +F   S     E                 K   + R  L   N     TP       + MD+WI S   S +K        Y L TV   L  + +  L + Y+   +  L+ E     E+ +        VLY +      ++SPF+PF+TE  +QRL     F          D   C   VH        +    P  E   +L+Q +V + R +R
Sbjct:  362 IVTDTTVDMTFGTGAVKLTPAHDHTDFLLSQKHSLPRLTVIGGNGTMT---SVCGQWLEGVKRFD------ARERVISALMERKLFRGKKDHPMSLPICSRSGDVIEPLLKK---QWFVRCQEMAKKAVQAVEEGDLQIIPQFYSK-MWKSWLSNISDWCVSRQLWWGHQIPAYRVTLQNSMNTEEEHWVWGRSAAEAQQRATIKF-GVNPEAI------------TLTQDPDVLDTWFSSGLFPFAMLGWPQQT--KDLTQFYPNSILETGSDLIFFWVARMVMLGTELTGQLPFKQVLFHSLVRDKYGRKMSKSLGNVIDPLDVISGVSLERLQEKVKEGNLDPRESIVAIEAQKKDFPKGIPECGTDALRFALCSYRAQGEDISLSMSHVLSCRHFCNKMWQTVRFTLATLNDASLPTPLAETYPLSSMDKWICSRLYSTVKECEQGFESYELHTVTSALHSFWLHCLCDVYLESIKPLLKPE---GCEERVGERQVATSVLYHSVSVSLALLSPFMPFLTEELWQRLLPYGHF----------DKTSCSLCVHPYPKTSQLEHWYFPKEEADFSLVQEVVRVTRLLR 911          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSD---TPLLNKAVPSWFIRVEDIVDQL--LTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELER-LSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPF-STDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISS----------------------PVVRGQSLKFV----ESGVRDMIKD---------FFIPWFNSFKFLFHS---SLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKY-IDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRL 2403
            ++ D +V  + GTG V   P    +DY V   + +       +  +DE G   N    F G+    A   ++Q LK++ +           P C RS     PLL    P W++   ++  Q   +  N E   +PD   +  F NW+ + RDW ISR  +WG  +P +     +  V  G   +    +SG   ++   ++     + +  +K  LR+  +V D WF SG  P++   +P  S D + F   +P   +  G D    W   + ++   + GK PFK +    +V  + G+KMSK L N  DPL+VI     + L   +  S                      P     +L+F      S  RD+  D         F    +N+ KF   +     VP EK Q  G            + ++ D WI+S   + +    G    Y   T+   +  + + +L + Y+   +           +       TL+  L     ++SP +PF++E  +QRL
Sbjct:  578 VVFDDFVDMNFGTGAVKITPAHDHNDYEVGERHKL-----PFINILDENGLLINVPPPFLGMKRFEARTAVLQALKDRGQFKEVKDNPMVVPVCSRSKDIVEPLLK---PQWYVDCREMGKQAADVVRNGELKIIPDHHLKTWF-NWMDNIRDWCISRQLWWGHRIPAYFVTVNDPAVKPGEDVDGHYWVSGRSEQEAREKAAKRFNVTA--DKISLRQDEDVLDTWFSSGIFPFSIFGWPNESEDLRVF---YPGTLLETGHDILFFWVARMVMMGLKLTGKLPFKEVYLHAVVRDAHGRKMSKSLGNVIDPLDVITGISLEGLYAQLADSNLDPLEIEKAKQGQKSDYPTGIPECGTDALRFALCAYTSQGRDINLDVNRILGYRHFCNKLWNAVKFAMRTLGEGFVPCEKAQLCG------------SESVSDRWILSRLSAAVALCDGGFKAYDFPTITTAIYNFWLYELCDVYLECVKPVFSRTDSKGQKQADVCRQTLYTCLEVGLRLLSPIMPFVSEELFQRL 1081          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWS--ESESVRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF YF K   E GAF ++ D+YV    GTGVVHQAPYFG DDYRVC+   II+K    VCPVD  G FT EVT F G YVK ADK II+ LKE  RL +  + KH+YPFCWRSDTPL+ KAVPSWF+RVE +VD+LL  N++ YWVP+FV+E RF NWLKDARDWAISRNRYWGTP+PLWVS+D+EEVVCVGS+AELE L+G KV DLHRES+D + IPS+  KG LRRV EVFDCWFESGSMPYAQVH+PF  + ++F + FPADFIAEGIDQTRGWFYTL V+ST +FG+ PFKN++ +G+VLASDGQKMSK  KNYPDP++VIN YG+DALR+Y+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL   ++    K++N     LF  +T  ++NN+MD+WIISFTQSL++FF+ +MS Y L TV PRL+K++D LTNWYVRMNR+RL+GE  S  ED   A+ TLF VL+    +++PF PFITE  YQ+L+  +D S + D        K  +S+HY+M+P   +DLI   IE +V+ MQ+++ELGR IRD+KTL +K PL EV+++ QD +++  I+S+E Y+ EELNVK++T+S +K KY + LRAE +H +LG +LK  ++ V+ A K L + QLEEFQ T  I + GHEL  ED+ ++ T +  +   D  +E+ S    +LVL+D      ++ E VARE+INRIQ+ RK+ NL+P D +TIY  S  E   +++V E H + I  T+  P+
Sbjct:  281 GNNLKGKKYKPLFPYFEK-ASERGAFTVVTDNYVKSEEGTGVVHQAPYFGADDYRVCMDFNIIQKDSVPVCPVDASGCFTKEVTDFAGQYVKDADKNIIKLLKEHGRLVHSSSYKHNYPFCWRSDTPLIYKAVPSWFVRVEHMVDKLLQNNSQCYWVPEFVREKRFGNWLKDARDWAISRNRYWGTPIPLWVSEDFEEVVCVGSLAELEELTGTKVTDLHRESVDHLTIPSRRGKGSLRRVTEVFDCWFESGSMPYAQVHYPFE-NRREFEDCFPADFIAEGIDQTRGWFYTLLVLSTALFGQPPFKNVIVNGLVLASDGQKMSKSKKNYPDPMQVINSYGSDALRMYLINSPVVRAENLRFKEDGVRDVLKDVFLPWYNAYRFLMQ-NIYRLHKEENIH--FLFNESTKQQSNNIMDQWIISFTQSLVQFFKAEMSAYRLYTVVPRLVKFVDMLTNWYVRMNRRRLKGE--SGTEDCQMALETLFSVLFSMCRLMAPFTPFITEMMYQKLRLLIDPSSMQD--------KDTKSIHYLMLPTAREDLIDKKIESAVSRMQSVIELGRVIRDRKTLPVKYPLKEVIVIHQDSEALADIKSLEKYIKEELNVKQVTVSTNKDKYGIRLRAEPDHMVLGKRLKGAFKTVMAAIKELKSNQLEEFQKTGSIVVDGHELHEEDIRLLYTFDQVS-GEDAHFEAHSDAQ-VLVLLDVTPDQSMVDEGVAREVINRIQKLRKKGNLVPTDEITIYYQSLPEGNYLQSVIERHTDFILATVKSPL 1041          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNI--QGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDRVASCNTKN 895
            M++   E+I+F  EE+ IL+ W  +  F+ CL+QSK++ +Y+FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  HVERRFGWDCHG+P   +  +K +   Q P     M         R+++++           +  W      Y  ++ +F+    ++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSVIVTFPL DDS   L+AWTTTPWTLPSNLALCVNP+L YVK+K+   G ++I+ME+R+  ++K+ N+ +I++R    N K 
Sbjct:    1 MAQQVPESINFPTEEEKILELWKSLDCFQECLKQSKNRPRYTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFHVERRFGWDCHGLPPLRQRSRKKDRGNQLPLFHSYMEGRQSTFSGRTLLLRVRGSVSYTSYGIVTWSSLLVLY--IFLFFVWDFRWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVIVTFPLLDDSGASLVAWTTTPWTLPSNLALCVNPELIYVKLKDKSNGNVYILMEARLSALYKAENEYDILERFPGNNLKG 286          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWS--ESESVRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF YF K   E GAF ++ D+YV    GTGVVHQAPYFG DDYRVC+   II+K    VCPVD  G FT EVT F G YVK ADK II+ LKE  RL +  + KH+YPFCWRSDTPL+ KAVPSWF+RVE +VD+LL  N++ YWVP+FV+E RF NWLKDARDWAISRNRYWGTP+PLWVS+D+EEVVCVGS+AELE L+G KV DLHRES+D + IPS+  KG LRRV EVFDCWFESGSMPYAQVH+PF  + ++F + FPADFIAEGIDQTRGWFYTL V+ST +FG+ PFKN++ +G+VLASDGQKMSK  KNYPDP++VIN YG+DALR+Y+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL   ++    K++N     LF  +T  ++NN+MD+WIISFTQSL++FF+ +MS Y L TV PRL+K++D LTNWYVRMNR+RL+GE  S  ED   A+ TLF VL+    +++PF PFITE  YQ+L+  +D S + D        K  +S+HY+M+P   +DLI   IE +V+ MQ+++ELGR IRD+KTL +K PL EV+++ QD +++  I+S+E Y+ EELNVK++T+S +K KY + LRAE +H +LG +LK  ++ V+ A K L + QLEEFQ T  I + GHEL  ED+ ++ T +  +   D  +E+ S    +LVL+D      ++ E VARE+INRIQ+ RK+ NL+P D +TIY  S  E   +++V E H + I  T+  P+
Sbjct:  278 GNNLKGKKYKPLFPYFEK-ASERGAFTVVTDNYVKSEEGTGVVHQAPYFGADDYRVCMDFNIIQKDSVPVCPVDASGCFTKEVTDFAGQYVKDADKNIIKLLKEHGRLVHSSSYKHNYPFCWRSDTPLIYKAVPSWFVRVEHMVDKLLQNNSQCYWVPEFVREKRFGNWLKDARDWAISRNRYWGTPIPLWVSEDFEEVVCVGSLAELEELTGTKVTDLHRESVDHLTIPSRRGKGSLRRVTEVFDCWFESGSMPYAQVHYPFE-NRREFEDCFPADFIAEGIDQTRGWFYTLLVLSTALFGQPPFKNVIVNGLVLASDGQKMSKSKKNYPDPMQVINSYGSDALRMYLINSPVVRAENLRFKEDGVRDVLKDVFLPWYNAYRFLMQ-NIYRLHKEENIH--FLFNESTKQQSNNIMDQWIISFTQSLVQFFKAEMSAYRLYTVVPRLVKFVDMLTNWYVRMNRRRLKGE--SGTEDCQMALETLFSVLFSMCRLMAPFTPFITEMMYQKLRLLIDPSSMQD--------KDTKSIHYLMLPTAREDLIDKKIESAVSRMQSVIELGRVIRDRKTLPVKYPLKEVIVIHQDSEALADIKSLEKYIKEELNVKQVTVSTNKDKYGIRLRAEPDHMVLGKRLKGAFKTVMAAIKELKSNQLEEFQKTGSIVVDGHELHEEDIRLLYTFDQVS-GEDAHFEAHSDAQ-VLVLLDVTPDQSMVDEGVAREVINRIQKLRKKGNLVPTDEITIYYQSLPEGNYLQSVIERHTDFILATVKSPL 1038          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVW---YIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDRVASCNTKN 895
            M++   E+I+F  EE+ IL+ W  +  F+ CL+QSK++ +Y+FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  HVERRFGWDCHG+P+  E  K  +++G      +      ++  +   + S     I   +G+     K    +   F+  VW   ++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSVIVTFPL DDS   L+AWTTTPWTLPSNLALCVNP+L YVK+K+   G ++I+ME+R+  ++K+ N+ +I++R    N K 
Sbjct:    1 MAQQVPESINFPTEEEKILELWKSLDCFQECLKQSKNRPRYTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFHVERRFGWDCHGLPVAKEQKKGQSLRG------LQCAKSTSDLVTDSKQLSAGKLCIHGCMGKMTMALKSSLLVLYIFLFFVWDFRWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVIVTFPLLDDSGASLVAWTTTPWTLPSNLALCVNPELIYVKLKDKSNGNVYILMEARLSALYKAENEYDILERFPGNNLKG 283          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWS--ESESVRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF YF K   E GAF ++ D+YV    GTGVVHQAPYFG DDYRVC+   II+K    VCPVD  G FT EVT F G YVK ADK II+ LKE  RL +  + KH+YPFCWRSDTPL+ KAVPSWF+RVE +VD+LL  N++ YWVP+FV+E RF NWLKDARDWAISRNRYWGTP+PLWVS+D+EEVVCVGS+AELE L+G KV DLHRES+D + IPS+  KG LRRV EVFDCWFESGSMPYAQVH+PF  + ++F + FPADFIAEGIDQTRGWFYTL V+ST +FG+ PFKN++ +G+VLASDGQKMSK  KNYPDP++VIN YG+DALR+Y+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL   ++    K++N     LF  +T  ++NN+MD+WIISFTQSL++FF+ +MS Y L TV PRL+K++D LTNWYVRMNR+RL+GE  S  ED   A+ TLF VL+    +++PF PFITE  YQ+L+  +D S + D        K  +S+HY+M+P   +DLI   IE +V+ MQ+++ELGR IRD+KTL +K PL EV+++ QD +++  I+S+E Y+ EELNVK++T+S +K KY + LRAE +H +LG +LK  ++ V+ A K L + QLEEFQ T  I + GHEL  ED+ ++ T +  +   D  +E+ S    +LVL+D      ++ E VARE+INRIQ+ RK+ NL+P D +TIY  S  E   +++V E H + I  T+  P+
Sbjct:  281 GNNLKGKKYKPLFPYFEK-ASERGAFTVVTDNYVKSEEGTGVVHQAPYFGADDYRVCMDFNIIQKDSVPVCPVDASGCFTKEVTDFAGQYVKDADKNIIKLLKEHGRLVHSSSYKHNYPFCWRSDTPLIYKAVPSWFVRVEHMVDKLLQNNSQCYWVPEFVREKRFGNWLKDARDWAISRNRYWGTPIPLWVSEDFEEVVCVGSLAELEELTGTKVTDLHRESVDHLTIPSRRGKGSLRRVTEVFDCWFESGSMPYAQVHYPFE-NRREFEDCFPADFIAEGIDQTRGWFYTLLVLSTALFGQPPFKNVIVNGLVLASDGQKMSKSKKNYPDPMQVINSYGSDALRMYLINSPVVRAENLRFKEDGVRDVLKDVFLPWYNAYRFLMQ-NIYRLHKEENIH--FLFNESTKQQSNNIMDQWIISFTQSLVQFFKAEMSAYRLYTVVPRLVKFVDMLTNWYVRMNRRRLKGE--SGTEDCQMALETLFSVLFSMCRLMAPFTPFITEMMYQKLRLLIDPSSMQD--------KDTKSIHYLMLPTAREDLIDKKIESAVSRMQSVIELGRVIRDRKTLPVKYPLKEVIVIHQDSEALADIKSLEKYIKEELNVKQVTVSTNKDKYGIRLRAEPDHMVLGKRLKGAFKTVMAAIKELKSNQLEEFQKTGSIVVDGHELHEEDIRLLYTFDQVS-GEDAHFEAHSDAQ-VLVLLDVTPDQSMVDEGVAREVINRIQKLRKKGNLVPTDEITIYYQSLPEGNYLQSVIERHTDFILATVKSPL 1041          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDRVASCNTKN 895
            M++   E+I+F  EE+ IL+ W  +  F+ CL+QSK++ +Y+FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  HVERRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CR IVM+YSQ+WE  V+RLGRWIDFK DYKT+YPWFME+VW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSVIVTFPL DDS   L+AWTTTPWTLPSNLALCVNP+L YVK+K+   G ++I+ME+R+  ++K+ N+ +I++R    N K 
Sbjct:    1 MAQQVPESINFPTEEEKILELWKSLDCFQECLKQSKNRPRYTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFHVERRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRGIVMRYSQEWEISVTRLGRWIDFKNDYKTLYPWFMETVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVIVTFPLLDDSGASLVAWTTTPWTLPSNLALCVNPELIYVKLKDKSNGNVYILMEARLSALYKAENEYDILERFPGNNLKG 286          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWS--ESESVRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF YF K   E GAF ++ D+YV    GTGVVHQAPYFG DDYRVC+   II+K    VCPVD  G FT EVT F G YVK ADK II+ LKE  RL +  + KH+YPFCWRSDTPL+ KAVPSWF+RVE +VD+LL  N++ YWVP+FV+E RF NWLKDARDWAISRNRYWGTP+PLWVS+D+EEVVCVGS+AELE L+G KV DLHRES+D + IPS+  KG LRRV EVFDCWFESGSMPYAQVH+PF  + ++F + FPADFIAEGIDQTRGWFYTL V+ST +FG+ PFKN++ +G+VLASDGQKMSK  KNYPDP++VIN YG+DALR+Y+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL   ++    K++N     LF  +T  ++NN+MD+WIISFTQSL++FF+ +MS Y L TV PRL+K++D LTNWYVRMNR+RL+GE  S  ED   A+ TLF VL+    +++PF PFITE  YQ+L+  +D S + D        K  +S+HY+M+P   +DLI   IE +V+ MQ+++ELGR IRD+KTL +K PL EV+++ QD +++  I+S+E Y+ EELNVK++T+S +K KY + LRAE +H +LG +LK  ++ V+ A K L + QLEEFQ T  I + GHEL  ED+ ++ T +  +   D  +E+ S    +LVL+D      ++ E VARE+INRIQ+ RK+ NL+P D +TIY  S  E   +++V E H + I  T+  P+
Sbjct:  281 GNNLKGKKYKPLFPYFEKA-SERGAFTVVTDNYVKSEEGTGVVHQAPYFGADDYRVCMDFNIIQKDSVPVCPVDASGCFTKEVTDFAGQYVKDADKNIIKLLKEHGRLVHSSSYKHNYPFCWRSDTPLIYKAVPSWFVRVEHMVDKLLQNNSQCYWVPEFVREKRFGNWLKDARDWAISRNRYWGTPIPLWVSEDFEEVVCVGSLAELEELTGTKVTDLHRESVDHLTIPSRRGKGSLRRVTEVFDCWFESGSMPYAQVHYPFE-NRREFEDCFPADFIAEGIDQTRGWFYTLLVLSTALFGQPPFKNVIVNGLVLASDGQKMSKSKKNYPDPMQVINSYGSDALRMYLINSPVVRAENLRFKEDGVRDVLKDVFLPWYNAYRFLMQ-NIYRLHKEENIH--FLFNESTKQQSNNIMDQWIISFTQSLVQFFKAEMSAYRLYTVVPRLVKFVDMLTNWYVRMNRRRLKGE--SGTEDCQMALETLFSVLFSMCRLMAPFTPFITEMMYQKLRLLIDPSSMQD--------KDTKSIHYLMLPTAREDLIDKKIESAVSRMQSVIELGRVIRDRKTLPVKYPLKEVIVIHQDSEALADIKSLEKYIKEELNVKQVTVSTNKDKYGIRLRAEPDHMVLGKRLKGAFKTVMAAIKELKSNQLEEFQKTGSIVVDGHELHEEDIRLLYTFDQVS-GEDAHFEAHSDAQ-VLVLLDVTPDQSMVDEGVAREVINRIQKLRKKGNLVPTDEITIYYQSLPEGNYLQSVIERHTDFILATVKSPL 1041          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDRVASCNTKN 895
            M++   E+I+F  EE+ IL+ W  +  F+ CL+QSK++ +Y+FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  HVERRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CR IVM+YSQ+WE  V+RLGRWIDFK DYKT+YPWFME+VW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSVIVTFPL DDS   L+AWTTTPWTLPSNLALCVNP+L YVK+K+   G ++I+ME+R+  ++K+ N+ +I++R    N K 
Sbjct:    1 MAQQVPESINFPTEEEKILELWKSLDCFQECLKQSKNRPRYTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFHVERRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRGIVMRYSQEWEISVTRLGRWIDFKNDYKTLYPWFMETVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVIVTFPLLDDSGASLVAWTTTPWTLPSNLALCVNPELIYVKLKDKSNGNVYILMEARLSALYKAENEYDILERFPGNNLKG 286          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWS--ESESVRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF YF K   E GAF ++ D+YV    GTGVVHQAPYFG DDYRVC+   II+K    VCPVD  G FT EVT F G YVK ADK II+ LKE  RL +  + KH+YPFCWRSDTPL+ KAVPSWF+RVE +VD+LL  N++ YWVP+FV+E RF NWLKDARDWAISRNRYWGTP+PLWVS+D+EEVVCVGS+AELE L+G KV DLHRES+D + IPS+  KG LRRV EVFDCWFESGSMPYAQVH+PF  + ++F + FPADFIAEGIDQTRGWFYTL V+ST +FG+ PFKN++ +G+VLASDGQKMSK  KNYPDP++VIN YG+DALR+Y+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL   ++    K++N     LF  +T  ++NN+MD+WIISFTQSL++FF+ +MS Y L TV PRL+K++D LTNWYVRMNR+RL+GE  S  ED   A+ TLF VL+    +++PF PFITE  YQ+L+  +D S + D        K  +S+HY+M+P   +DLI   IE +V+ MQ+++ELGR IRD+KTL +K PL EV+++ QD +++  I+S+E Y+ EELNVK++T+S +K KY + LRAE +H +LG +LK  ++ V+ A K L + QLEEFQ T  I + GHEL  ED+ ++ T +  +   D  +E+ S    +LVL+D      ++ E VARE+INRIQ+ RK+ NL+P D +TIY  S  E   +++V E H + I  T+  P+
Sbjct:  281 GNNLKGKKYKPLFPYFEK-ASERGAFTVVTDNYVKSEEGTGVVHQAPYFGADDYRVCMDFNIIQKDSVPVCPVDASGCFTKEVTDFAGQYVKDADKNIIKLLKEHGRLVHSSSYKHNYPFCWRSDTPLIYKAVPSWFVRVEHMVDKLLQNNSQCYWVPEFVREKRFGNWLKDARDWAISRNRYWGTPIPLWVSEDFEEVVCVGSLAELEELTGTKVTDLHRESVDHLTIPSRRGKGSLRRVTEVFDCWFESGSMPYAQVHYPFE-NRREFEDCFPADFIAEGIDQTRGWFYTLLVLSTALFGQPPFKNVIVNGLVLASDGQKMSKSKKNYPDPMQVINSYGSDALRMYLINSPVVRAENLRFKEDGVRDVLKDVFLPWYNAYRFLMQ-NIYRLHKEENIH--FLFNESTKQQSNNIMDQWIISFTQSLVQFFKAEMSAYRLYTVVPRLVKFVDMLTNWYVRMNRRRLKGE--SGTEDCQMALETLFSVLFSMCRLMAPFTPFITEMMYQKLRLLIDPSSMQD--------KDTKSIHYLMLPTAREDLIDKKIESAVSRMQSVIELGRVIRDRKTLPVKYPLKEVIVIHQDSEALADIKSLEKYIKEELNVKQVTVSTNKDKYGIRLRAEPDHMVLGKRLKGAFKTVMAAIKELKSNQLEEFQKTGSIVVDGHELHEEDIRLLYTFDQVS-GEDAHFEAHSDAQ-VLVLLDVTPDQSMVDEGVAREVINRIQKLRKKGNLVPTDEITIYYQSLPEGNYLQSVIERHTDFILATVKSPL 1041          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDRVASCNTKN 895
            M++   E+I+F  EE+ IL+ W  +  F+ CL+QSK++ +Y+FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  HVERRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CR IVM+YSQ+WE  V+RLGRWIDFK DYKT+YPWFME+VW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSVIVTFPL DDS   L+AWTTTPWTLPSNLALCVNP+L YVK+K+   G ++I+ME+R+  ++K+ N+ +I++R    N K 
Sbjct:    1 MAQQVPESINFPTEEEKILELWKSLDCFQECLKQSKNRPRYTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFHVERRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRGIVMRYSQEWEISVTRLGRWIDFKNDYKTLYPWFMETVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVIVTFPLLDDSGASLVAWTTTPWTLPSNLALCVNPELIYVKLKDKSNGNVYILMEARLSALYKAENEYDILERFPGNNLKG 286          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESES--VRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF+YFIK K E GAF ++ D YV +  GTGVVHQAPYFG DD+RVC+   II+K    VCPVD  G FT EVTHF G YVK ADK II+ LKE+ RL   GT  HSYPFCWRSDTPL+ K+VPSWF+RVE +VDQLL  N   YWVP+FV+E RF NWLK+ARDWAISRNRYWGTP+PLWVS+D EEVVC+GS+AELE LSG K+ DLHRESID + IPS+  K  LRRV EVFDCWFESGSMPYAQVH+PF +  ++F + FPADFIAEGIDQTRGWFYTL V++T +FG+ PFKN++ +G++LASDGQKMSKR KNYPDP+ +I+KYGADALRLY+I+SPVVR ++L+F E GVRD++KD  +PW+N+++F   +    F   +      L+  +T  ++ N+ D W++SF QSL+ FF  +M+ Y L TV PRL+K++D LTNWYVRMNR+RL+GE  S  ED + A+ TLF VL     +++P+ PF+TE  YQ LK  +D + + D        K   S+HY+M+P   ++LI    E +V+ MQ+++ELGR IRD+KT+ +K PL E+V++ QD ++++ I S+E Y++EELNV+K+TLS DK KY + LRAE +H +LG +LK  ++AV+ A K L+ E+LE FQ +  I + GHEL  ED+ ++ T +     T  Q+E+ S     LVL+D      ++ E +ARE+INRIQ+ RK+ NL+P D +T+Y  ++SE   +  V ESH + I+ TI  P+
Sbjct:  281 GASLKGKKYKPLFDYFIKCK-ENGAFTVLVDHYVKDEEGTGVVHQAPYFGADDHRVCMDFNIIQKDSVPVCPVDASGCFTEEVTHFVGQYVKDADKNIIRMLKEQGRLLAAGTFTHSYPFCWRSDTPLIYKSVPSWFVRVEPMVDQLLKNNDLCYWVPEFVREKRFGNWLKEARDWAISRNRYWGTPIPLWVSEDLEEVVCIGSVAELEELSGTKISDLHRESIDHLTIPSRCGKAPLRRVSEVFDCWFESGSMPYAQVHYPFESK-REFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLILASDGQKMSKRKKNYPDPVSIIDKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFFIQNV---FRLHKEEEVKFLYNEHTVRESPNITDRWVLSFMQSLLGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGE--SGVEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKLLIDPASLRD--------KDTLSIHYLMLPRVREELIDKKTENAVSRMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALEDIRSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMMAIKRLSNEELERFQKSGSIVVEGHELHEEDIRLMYTFDQATGGT-AQFEAHSDAQA-LVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGRYLNNVIESHTDFIFATIKAPL 1041          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDRVASCNTKN 895
            M +   E ISF  EE+ IL++W++   F+ CL+QSK + K++FYDGPPFATG+PHYGH+LAG++KDIVTR+AHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CR+IVM+YS +W+  V+RLGRWIDF  DYKT+YP FMESVW++FKQ+++KGLVYRGVKVMPFSTAC TPLSNFE+ QNYKDV DPSV VTFPL +D +T L+AWTTTPWTLPSNLALCVNP++ YVK+K+V  GKLFI+ E+R+  ++K  +  EI++R    + K 
Sbjct:    1 MVQQVPENISFPAEEEKILEFWSKHNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRAIVMRYSAEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACGTPLSNFESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNPEIQYVKIKDVARGKLFILTEARLSALYKQESDYEILERFPGASLKG 286          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESES--VRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF+YFIK K E GAF ++ D YV +  GTGVVHQAPYFG DD+RVC+   II+K    VCPVD  G FT EVTHF G YVK ADK II+ LKE+ RL   GT  HSYPFCWRSDTPL+ K+VPSWF+RVE +VDQLL  N   YWVP+FV+E RF NWLK+ARDWAISRNRYWGTP+PLWVS+D EEVVC+GS+AELE LSG K+ DLHRESID + IPS+  K  LRRV EVFDCWFESGSMPYAQVH+PF +  ++F + FPADFIAEGIDQTRGWFYTL V++T +FG+ PFKN++ +G++LASDGQKMSKR KNYPDP+ +I+KYGADALRLY+I+SPVVR ++L+F E GVRD++KD  +PW+N+++F   +    F   +      L+  +T  ++ N+ D W++SF QSL+ FF  +M+ Y L TV PRL+K++D LTNWYVRMNR+RL+GE  S  ED + A+ TLF VL     +++P+ PF+TE  YQ LK  +D + + D        K   S+HY+M+P   ++LI    E +V+ MQ+++ELGR IRD+KT+ +K PL E+V++ QD ++++ I S+E Y++EELNV+K+TLS DK KY + LRAE +H +LG +LK  ++AV+ A K L+ E+LE FQ +  I + GHEL  ED+ ++ T +     T  Q+E+ S     LVL+D      ++ E +ARE+INRIQ+ RK+ NL+P D +T+Y  ++SE   +  V ESH + I+ TI  P+
Sbjct:  281 GASLKGKKYKPLFDYFIKCK-ENGAFTVLVDHYVKDEEGTGVVHQAPYFGADDHRVCMDFNIIQKDSVPVCPVDASGCFTEEVTHFVGQYVKDADKNIIRMLKEQGRLLAAGTFTHSYPFCWRSDTPLIYKSVPSWFVRVEPMVDQLLKNNDLCYWVPEFVREKRFGNWLKEARDWAISRNRYWGTPIPLWVSEDLEEVVCIGSVAELEELSGTKISDLHRESIDHLTIPSRCGKAPLRRVSEVFDCWFESGSMPYAQVHYPFESK-REFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLILASDGQKMSKRKKNYPDPVSIIDKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFFIQNV---FRLHKEEEVKFLYNEHTVRESPNITDRWVLSFMQSLLGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGE--SGVEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKLLIDPASLRD--------KDTLSIHYLMLPRVREELIDKKTENAVSRMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALEDIRSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMMAIKRLSNEELERFQKSGSIVVEGHELHEEDIRLMYTFDQATGGT-AQFEAHSDAQA-LVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGRYLNNVIESHTDFIFATIKAPL 1041          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDRVASCNTKN 895
            M +   E ISF  EE+ IL++W++   F+ CL+QSK + K++FYDGPPFATG+PHYGH+LAG++KDIVTR+AHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CR+IVM+YS +W+  V+RLGRWIDF  DYKT+YP FMESVW++FKQ+++KGLVYRGVKVMPFSTAC TPLSNFE+ QNYKDV DPSV VTFPL +D +T L+AWTTTPWTLPSNLALCVNP++ YVK+K+V  GKLFI+ E+R+  ++K  +  EI++R    + K 
Sbjct:    1 MVQQVPENISFPAEEEKILEFWSKHNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRAIVMRYSAEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACGTPLSNFESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNPEIQYVKIKDVARGKLFILTEARLSALYKQESDYEILERFPGASLKG 286          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESES--VRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF+YFIK K E GAF ++ D YV +  GTGVVHQAPYFG DD+RVC+   II+K    VCPVD  G FT EVTHF G YVK ADK II+ LKE+ RL   GT  HSYPFCWRSDTPL+ K+VPSWF+RVE +VDQLL  N   YWVP+FV+E RF NWLK+ARDWAISRNRYWGTP+PLWVS+D EEVVC+GS+AELE LSG K+ DLHRESID + IPS+  K  LRRV EVFDCWFESGSMPYAQVH+PF +  ++F + FPADFIAEGIDQTRGWFYTL V++T +FG+ PFKN++ +G++LASDGQKMSKR KNYPDP+ +I+KYGADALRLY+I+SPVVR ++L+F E GVRD++KD  +PW+N+++F   +    F   +      L+  +T  ++ N+ D W++SF QSL+ FF  +M+ Y L TV PRL+K++D LTNWYVRMNR+RL+GE  S  ED + A+ TLF VL     +++P+ PF+TE  YQ LK  +D + + D        K   S+HY+M+P   ++LI    E +V+ MQ+++ELGR IRD+KT+ +K PL E+V++ QD ++++ I S+E Y++EELNV+K+TLS DK KY + LRAE +H +LG +LK  ++AV+ A K L+ E+LE FQ +  I + GHEL  ED+ ++ T +     T  Q+E+ S     LVL+D      ++ E +ARE+INRIQ+ RK+ NL+P D +T+Y  ++SE   +  V ESH + I+ TI  P+
Sbjct:  281 GASLKGKKYKPLFDYFIKCK-ENGAFTVLVDHYVKDEEGTGVVHQAPYFGADDHRVCMDFNIIQKDSVPVCPVDASGCFTEEVTHFVGQYVKDADKNIIRMLKEQGRLLAAGTFTHSYPFCWRSDTPLIYKSVPSWFVRVEPMVDQLLKNNDLCYWVPEFVREKRFGNWLKEARDWAISRNRYWGTPIPLWVSEDLEEVVCIGSVAELEELSGTKISDLHRESIDHLTIPSRCGKAPLRRVSEVFDCWFESGSMPYAQVHYPFESK-REFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLILASDGQKMSKRKKNYPDPVSIIDKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFFIQNV---FRLHKEEEVKFLYNEHTVRESPNITDRWVLSFMQSLLGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGE--SGVEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKLLIDPASLRD--------KDTLSIHYLMLPRVREELIDKKTENAVSRMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALEDIRSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMMAIKRLSNEELERFQKSGSIVVEGHELHEEDIRLMYTFDQATGGT-AQFEAHSDAQA-LVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGRYLNNVIESHTDFIFATIKAPL 1041          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDRVASCNTKN 895
            M +   E ISF  EE+ IL++W++   F+ CL+QSK + K++FYDGPPFATG+PHYGH+LAG++KDIVTR+AHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CR+IVM+YS +W+  V+RLGRWIDF  DYKT+YP FMESVW++FKQ+++KGLVYRGVKVMPFSTAC TPLSNFE+ QNYKDV DPSV VTFPL +D +T L+AWTTTPWTLPSNLALCVNP++ YVK+K+V  GKLFI+ E+R+  ++K  +  EI++R    + K 
Sbjct:    1 MVQQVPENISFPAEEEKILEFWSKHNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRAIVMRYSAEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACGTPLSNFESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNPEIQYVKIKDVARGKLFILTEARLSALYKQESDYEILERFPGASLKG 286          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTH--FEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESI-----DDIIIPSKM-----NKGVLRRVP--EVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVIN---------KYGADALRLYMISSPVVRGQSL-KFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIK--YIDQLTNWYVRMNRKRL--RGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRL 2403
            ++  ++VT + GTG+VH AP  G +DY V   + +      + C VDE G FT+           +K    ++I+ L+  K +       HSYP  WR+ TP+L +A   WF+ + DI      +     ++P     N  T+ L     W ISR R WG P+P++     +E +      E      +K+ + H   +      + ++P+++       G L   P  ++ D WF+SG+     +      D +Q      AD   EG DQ  GWF +  + S     KAPF+ ++  G  L   G+KMSK L N  +P  +I+          YGAD LR ++  S V    ++   V S  RD I        N+ +FL   +L  F  + +S          P K   ++D++++   Q           +Y    V  RL+K  Y  +L+++Y  + + RL    E         +A+  +  VL +A    +P +P + E  +Q +
Sbjct:  376 LLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHSL-----PMDCLVDEGGMFTDAAGPELQNKAVLKEGTDVVIKMLQATKNVLKEENIVHSYPCDWRTKTPVLIRASKQWFVNITDIKAAAKESLKTVKFIPG-AALNSMTDMLDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTE----HIIKLVEQHGSDVWWTLPAEQLLPAEVLAQAGGPGALEYAPGQDILDIWFDSGTSWSCVLQ-----DTQQR-----ADLYLEGKDQLGGWFQSSLLTSVATRSKAPFRTVMVHGFTLGEKGEKMSKSLGNVINPDTIISGGKDHSKEPPYGADILRWWIAESNVFTEVTIGPSVLSAARDDISKL----RNTLRFLL-GNLTGFNPETDS---------VPVKNMYVIDQYMLHLIQDFATKITDSYKQYDFGKVV-RLLKAFYTRELSSFYFSIVKDRLYCENEKDPKRRSCQTALAEILDVLVRA---FAPILPHLAEEVFQHI 849          

Query:  140 QSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFP----------LRDDSSXXXXXX-XXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYV 838
            + K K ++  +DGPP+A G PH GH L   +KDI  RF       V    GWDCHG+PIE ++  +L +    D   +       + RS      +  +    R G   D+   Y T  P +      +F Q++EKGLVYR  K + +S +  T L+  E + N + V+  S+ V FP          L D SS   +   TT PWT+P+N A+C  P+  Y  VK   +G L+I+ E +I  V
Sbjct:  102 ERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMRGSKVHFVPGWDCHGLPIETKVLSELGV----DAQSLSAMEIREKARSFAQAAIEKQKSAFVRWGVMADWNNCYYTFDPKYEAKQLRVFYQMYEKGLVYRSYKPVYWSPSSRTALAEAELEYNPEHVSR-SIYVRFPLLRPPPKLESLTDASSPVSVLVWTTQPWTIPANQAICYMPEAKYAVVKCSASGHLYILAEDKIAPV 340          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTH--FEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESI-----DDIIIPSKM-----NKGVLRRVP--EVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINK---------YGADALRLYMISSPV 1932
            ++  ++VT + GTG+VH AP  G +DY V   + +      + C VDE G FT+           +K    ++I+ L+  K +       HSYP  WR+ TP+L +A   WF+ + DI      +     ++P     N  T+ L     W ISR R WG P+P++     +E +      E      +K+ + H   +      + ++P+++       G L   P  ++ D WF+SG+     +      D +Q      AD   EG DQ  GWF +  + S     KAPF+ ++  G  L   G+KMSK L N  +P  +I+          YGAD LR ++  S V
Sbjct:  376 LLPATHVTMAKGTGLVHTAPAHGMEDYSVASQHSL-----PMDCLVDEGGMFTDAAGPELQNKAVLKEGTDVVIKMLQATKNVLKEENIVHSYPCDWRTKTPVLIRASKQWFVNITDIKAAAKESLKTVKFIPG-AALNSMTDMLDRRPYWCISRQRVWGVPIPVFHHKTKDEYLINSQTTE----HIIKLVEQHGSDVWWTLPAEQLLPAEVLAQAGGPGALEYAPGQDILDIWFDSGTSWSCVLQ-----DTQQR-----ADLYLEGKDQLGGWFQSSLLTSVATRSKAPFRTVMVHGFTLGEKGEKMSKSLGNVINPDTIISGGKDHSKEPPYGADILRWWIAESNV 705          

Query:  140 QSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFP----------LRDDSSXXXXXX-XXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS 847
            + K K ++  +DGPP+A G PH GH L   +KDI  RF       V    GWDCHG+PIE ++  +L +    D   +       + RS      +  +    R G   D+   Y T  P +      +F Q++EKGLVYR  K + +S +  T L+  E + N + V+  S+ V FP          L D SS   +   TT PWT+P+N A+C  P+  Y  VK   +G L+I+ E +I  V  +
Sbjct:  102 ERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRFHMMRGSKVHFVPGWDCHGLPIETKVLSELGV----DAQSLSAMEIREKARSFAQAAIEKQKSAFVRWGVMADWNNCYYTFDPKYEAKQLRVFYQMYEKGLVYRSYKPVYWSPSSRTALAEAELEYNPEHVSR-SIYVRFPLLRPPPKLESLTDASSPVSVLVWTTQPWTIPANQAICYMPEAKYAVVKCSASGHLYILAEDKIAPVASA 343          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESES--VRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF+YF+K K E GAF ++ D+YV E  GTGVVHQAPYFG +DYRVC+   IIRK    VCPVD  G FT EVT F G YVK ADK II+ LKE+ RL    T  HSYPFCWRSDTPL+ KAVPSWF+RVE++VDQLL  N   YWVP+ V+E RF NWLKDARDW ISRNRYWGTP+PLWVSDD+EEVVC+GS+AELE LSG K+ DLHRES+D + IPS+  KG L R+ EVFDCWFESGSMPYAQVH+PF    ++F + FPADFIAEGIDQTRGWFYTL V++T +FG+ PFKN++ +G+VLASDGQKMSKR KNYPDP+ +I KYGADALRLY+I+SPVVR ++L+F E GVRD++KD  +PW+N+++FL  + L     ++      L+  NT  ++ N+ D WI+SF QSLI FF  +M+ Y L TV PRL+K++D LTNWYVRMNR+RL+GE  +  ED + A+ TLF VL     +++P+ PF+TE  YQ LK  +D   + D        K   S+HY+M+P   ++LI    E +V+ MQ+++ELGR IRD+KT+ +K PL E+V++ QD +++K I+S+E Y++EELNV+K+TLS DK KY + LRAE +H +LG +LK  ++AV+ + K L++E+LE+FQ T  I + GHEL  ED+ ++ T +     T  Q+E+ S     LVL+D      ++ E +ARE+INRIQ+ RK+ NL+P D +T+Y  ++SE   + +V ESH E I+ TI  P+
Sbjct:  281 GAYLKGKKYRPLFDYFLKCK-ENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFAGQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPLWVSDDFEEVVCIGSVAELEELSGAKISDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENK-REFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFLIQNVL---RLQKEEEIEFLYNENTVRESPNITDRWILSFMQSLIGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGE--NGMEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKVLIDPVSVQD--------KDTLSIHYLMLPRVREELIDKKTESAVSQMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALKDIKSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMTSIKQLSSEELEQFQKTGTIVVEGHELHDEDIRLMYTFDQATGGT-AQFEAHSDAQA-LVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKAKSEGTYLNSVIESHTEFIFTTIKAPL 1041          

Query:   59 EAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFK-SNQVEIVDR 871
            E I+F  EE+ IL++W E   F+ CL+QSKHK K++FYDGPPFATG+PHYGH+LAG++KDIVTR+AHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGIT YNN+CR+IVM+YS +W+  VSRLGRWIDF  DYKT+YP FMESVW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSV VTFPL +D +  L+AWTTTPWTLPSNLA+CVNP++ YVK+K+V  G+L I+ME+R+  ++K  +  EI++R
Sbjct:    7 ENINFPAEEEKILEFWTEFNCFQECLKQSKHKPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKMGITEYNNQCRAIVMRYSAEWKSTVSRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVFVTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLSALYKLESDYEILER 278          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESES--VRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLF+YFIK K E GAF ++ D YV +  GTGVVHQAPYFG DD+RVC+   II+K    VCPVD  G FT EVTHF G YVK ADK II+ LKE+ RL   GT  HSYPFCWRSDTPL+ K+VPSWF+RVE +VDQLL  N   YWVP+FV+E RF NWLK+ARDWAISRNRYWGTP+PLWVS+D EEVVC+GS+AELE LSG K+ DLHRESID + IPS+  K  LRRV EVFDCWFESGSMPYAQVH+PF +  ++F + FPADFIAEGIDQTRGWFYTL V++T +FG+ PFKN++ +G++LASDGQKMSKR KNYPDP+ +I+KYGADALRLY+I+SPVVR ++L+F E GVRD++KD  +PW+N+++F   +    F   +      L+  +T  ++ N+ D W++SF QSL+ FF  +M+ Y L TV PRL+K++D LTNWYVRMNR+RL+GE  S  ED + A+ TLF VL     +++P+ PF+TE  YQ LK  +D + + D        K   S+HY+M+P   ++LI    E +V+ MQ+++ELGR IRD+KT+ +K PL E+V++ QD ++++ I S+E Y++EELNV+K+TLS DK KY + LRAE +H +LG +LK  ++AV+ A K L+ E+LE FQ +  I + GHEL  ED+ ++ T +     T  Q+E+ S     LVL+D      ++ E +ARE+INRIQ+ RK+ NL+P D +T+Y  ++SE   +  V ESH + I+ TI  P+
Sbjct:  281 GASLKGKKYKPLFDYFIKCK-ENGAFTVLVDHYVKDEEGTGVVHQAPYFGADDHRVCMDFNIIQKDSVPVCPVDASGCFTEEVTHFVGQYVKDADKNIIRMLKEQGRLLAAGTFTHSYPFCWRSDTPLIYKSVPSWFVRVEPMVDQLLKNNDLCYWVPEFVREKRFGNWLKEARDWAISRNRYWGTPIPLWVSEDLEEVVCIGSVAELEELSGTKISDLHRESIDHLTIPSRCGKAPLRRVSEVFDCWFESGSMPYAQVHYPFESK-REFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLILASDGQKMSKRKKNYPDPVSIIDKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAYRFFIQNV---FRLHKEEEVKFLYNEHTVRESPNITDRWVLSFMQSLLGFFETEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGE--SGVEDCVMALETLFSVLLSLCRLMAPYTPFLTELMYQNLKLLIDPASLRD--------KDTLSIHYLMLPRVREELIDKKTENAVSRMQSVIELGRVIRDRKTIPIKYPLKEIVVIHQDPEALEDIRSLEKYIIEELNVRKVTLSTDKNKYGIRLRAEPDHMVLGKRLKGAFKAVMMAIKRLSNEELERFQKSGSIVVEGHELHEEDIRLMYTFDQATGGT-AQFEAHSDAQA-LVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYNAKSEGRYLNNVIESHTDFIFATIKAPL 1041          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDRVASCNTKN 895
            M +   E ISF  EE+ IL++W++   F+ CL+QSK + K++FYDGPPFATG+PHYGH+LAG++KDIVTR+AHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CR+IVM+YS +W+  V+RLGRWIDF  DYKT+YP FMESVW++FKQ+++KGLVYRGVKVMPFSTAC TPLSNFE+ QNYKDV DPSV VTFPL +D +T L+AWTTTPWTLPSNLALCVNP++ YVK+K+V  GKLFI+ E+R+  ++K  +  EI++R    + K 
Sbjct:    1 MVQQVPENISFPAEEEKILEFWSKHNCFQECLKQSKLRPKFTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRAIVMRYSAEWKSTVTRLGRWIDFDNDYKTLYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACGTPLSNFESNQNYKDVQDPSVFVTFPLEEDENTSLVAWTTTPWTLPSNLALCVNPEIQYVKIKDVARGKLFILTEARLSALYKQESDYEILERFPGASLKG 286          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTE-QLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECS----ILSDTSGTSSEVKDSILSMWFTHDHNRLKTDNRKCLPKSSNVEVICDGDLNSVVQLDVMGIDSWDELLRHVRVAFE-WRRFAVAPVTLLDVNDKPIAP-VAPSTLKGQ 3564
            G +L+   Y PLF YF  M++E  AFR++ D++VT  SGTGVVHQAPYFGE D++VC++NG+I K   ++CPVDE GK+T+EV  ++G+YVK ADKLII+ LKE   L      KHSYPFCWRSDTPLL KAVPSWFI VE ++ +LL  N ETYWVP FVKE RF NWL+DARDWA+SRNR+WGTP+ LWVS+D EEVVCVGSIAELE LSG K+ DLHRES+DD+ IPS+  +GVL+RV EVFDCWFESGSMPYAQ H+PF  + K F + FPADFIAEGIDQTRGWFYTL V+ST +F K PFKNL+C+G+VLASDG KMSK  KNYPDP+ ++NKYGADALRLY+I+SPVVRG++L+F E GVRD++KD F+PWFN+++F F  ++  +E +  +    +F  N    + N+MD WI SFT SL+ F R +M  Y L  V   L K+ D LTN Y+R+NRKR++G+  +   +   A+  L  VL     +++PF PF  E+ +  LK+ +  +E              ESVH++M+P+ ++ LI   +E  V +M+ +++L R +RD++ LA+K PL E++++++D   ++ ++S+ESY+L ELNV+KLT+S DK+KY + L+AE N ++LG +LK + + V    K   TE +LE+F    K+T+LGHEL SE++ V     +D       Y++ S    I V++D  + + L++E + RE+ NR+QR RK+  L+  D   ++       V +  +S    +    L  I+    ++   PI   S      + T+ + S +KDS + +W   + +    D    +  S  V V         V+ +   +  + +LL HVR A + W       + L +V+   + P V  ++L GQ
Sbjct:  281 GSQLKDLRYEPLFPYFAYMREERNAFRVLNDTFVTSDSGTGVVHQAPYFGEIDFQVCVANGVIAKDQKMICPVDESGKYTSEVPDYQGVYVKDADKLIIKRLKEMGNLVRQAEVKHSYPFCWRSDTPLLYKAVPSWFINVETLIPRLLANNDETYWVPAFVKEKRFANWLRDARDWAVSRNRFWGTPINLWVSEDGEEVVCVGSIAELEELSGQKITDLHRESVDDVTIPSRSGRGVLKRVSEVFDCWFESGSMPYAQNHYPFE-NRKIFEDNFPADFIAEGIDQTRGWFYTLLVLSTALFNKPPFKNLICNGLVLASDGAKMSKSKKNYPDPMLIVNKYGADALRLYLINSPVVRGENLRFREEGVRDLLKDVFLPWFNAYRF-FVQNVQAYEHETGN----VFDMNVHVASENVMDRWIESFTNSLVAFVRKEMDSYRLYAVVGPLTKFFDTLTNIYIRLNRKRVKGD--NGLHEQHHALAALGRVLILIVRLMAPFTPFFCEYIWLNLKKVIGSTE--------------ESVHFLMLPKPDESLIDETVERRVEVMRNVIDLVRLVRDREGLAVKYPLKEMIVINRDSQFLEDVKSLESYILLELNVRKLTVSQDKQKYGITLKAEPNFKILGARLKGEQKKVADYLKNQITESELEKFLLEGKLTVLGHELSSEEVAVSYAAGSDQGHG---YKTHSDAKTI-VMIDTTEDESLIEEGLCREVTNRVQRLRKQAKLVSTDTAHVHI------VVSPADSQLAKVVAAKLNDIV----SATGTPIKLGSPPAAAKAPTATSKSAIKDSEVELWLFAEGDSF--DGITVVDGSKKVRVH--------VKTEKEHLKGYADLLYHVRSALDLWN----GKIALKNVDGSAVHPTVDVTSLVGQ 1135          

Query:   65 ISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEIVDRVASCNTKNTFRY 907
            I+FA EE  + + W +   F+  +E SK +  ++FYDGPPFATG+PHYGH+L  ++KD+V R+AHQ  H+VERRFGWD HG+P+EYEIDK L I GP DVMKMGI  YNNECR IVM+YS +WE  + RLGRW+DFK DYKT+YPWFMESVW+ F ++ +KGLVY+GVKVMPFSTACSTPLSNFEA QNYKDV DP+V V F L D  + +L+AWTTTPWTLPSNLAL V+PD+ YV  K+  TG  ++++E R+G + K++ +E+++++A    K+  RY
Sbjct:   11 INFAREEDKVAQKWQDENTFQRSVELSKDRPHFTFYDGPPFATGLPHYGHMLTSTIKDVVGRWAHQNGHYVERRFGWDTHGLPVEYEIDKTLGISGPQDVMKMGIANYNNECRKIVMRYSGEWEKTMGRLGRWVDFKHDYKTLYPWFMESVWWAFSELHKKGLVYKGVKVMPFSTACSTPLSNFEAGQNYKDVVDPAVFVGFKLLDCPNRQLVAWTTTPWTLPSNLALVVHPDMLYVVTKDKTTGIEYVVLEERLGEL-KNDNLEVIEKLAGSQLKD-LRY 289          

Query:  787 SKNRQTLHYNGIKNRICFQIKSSGNC**GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRK---AGTIVCPVDECGKFTNEVTHFEGIYVKTAD--KLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPN--TPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDG---ILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICE--CSILSDTSG 3267
             KNR ++ Y   K     +         G +L  K+Y+P+F YF       G F ++   +VT+ SGTG+VH AP +GEDD+ VC++NG+I +      I+  VD  G FT++VT F G+ VK A+  K I  +LK K R+ N     HSYP+CWRSDTPL+ KAV SWF+RVE I D+LL  N +TYWVPDFVKE RF NWLK+A DWA+SRNRYWGTP+PLW+S+D EEVV +GSI ELERLSGV+V DLHRESID I IPS+  KG LRR+ +VFDCWFESGSMPYAQ H+PF    K F +IFPA FIAEG+DQTRGWFYTL V+ST +F K PF+NL+ +G+VLA+DG+KMSKRLKNYPDP+EV++K GAD+LRLY+I+SPVVR ++LKF E GV+DMIKD F+PWFN+++F   + L  FEK  N+     F+P+      + N+MD+WI++  QSLI F R +M+ Y L TV P+L+++I+ LTNW+VR+NRKRL+G   + + D ++A++ L+ VL    + + PF PF TE+ YQ LK+ L              +K  +SVHY+M PE  ++     IEE+++ MQ ++ELGR  RD++T  +K PL E ++++++   +  +ES++SY+LEELN++ + L++D+  + V + AE +++ LG +LK D++ +      LT EQL EFQ T  I ILGHEL SEDL++I   N +         + S P G   IL ++D      L ++ +ARE+INR+QR RK+  L  +DPV+++  ++   ++   E++ + I  TIL  +    T S  N       SI+ D   
Sbjct:  258 GKNRTSILYKSDKEYTVLETMK------GTDLIGKKYVPMFPYFAS-DANMGGFVVIGGDFVTDDSGTGIVHTAPAYGEDDFNVCIANGVISRDQFKRPILNSVDANGCFTSDVTDFAGMMVKDAETTKQISIYLKNKGRMVNSANLVHSYPYCWRSDTPLIYKAVGSWFVRVESIRDKLLANNDKTYWVPDFVKEKRFANWLKNATDWAVSRNRYWGTPIPLWISEDGEEVVVIGSIDELERLSGVRVTDLHRESIDHITIPSQKGKGTLRRIEDVFDCWFESGSMPYAQQHYPFENKDK-FEKIFPAHFIAEGLDQTRGWFYTLLVLSTALFDKPPFQNLIVNGLVLAADGKKMSKRLKNYPDPMEVVSKVGADSLRLYLINSPVVRAETLKFQEKGVQDMIKDVFLPWFNAYRFFVQNCL-RFEKATNT----TFQPDIKVALASENVMDKWILASCQSLIAFVRAEMAAYRLYTVVPKLVRFIEDLTNWFVRLNRKRLKGS--NGDADCLAALNILYEVLMTICIAMGPFTPFFTEYMYQNLKKAL------------PKEKQMDSVHYVMFPEPIQEAFNTRIEEAISRMQVVIELGRAARDRRTKPIKFPLKEFMVITENQQYLADLESLKSYILEELNIQNIVLTSDEGSF-VVVTAEADNKRLGARLKNDFKKISPLISKLTNEQLREFQKTQTIDILGHELTSEDLKIIRKYNGET--------TNSEPSGNEEILTVLDLTVDSALYEKGLARELINRVQRLRKKSGLTFDDPVSMFYHTKEAELKTAIENNNDYIKETILFNLQFSETTSPSNSFATEIVSIVKDNDA 1060          

Query:   59 EAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQ 853
            + I FA EE  ILKYW++IKAFET ++ S+ K +YSFYDGPPFATG+PHYGH+LAG++KD +TR+AHQT HHVERRFGWDCHG+PIE+EIDK   ++   DV+KMGI  YN  CRSIVMKYS +WE +V+R+GRWID K +YKTM   FMESVW++F+++F+K LVY+G KVMP+S  C+TPLSNFEA  NYKDV+DP+ +V+F   DD    +LAWTTTPWTLPSNLAL VNP ++Y+K+ ++K  ++FI+ ++R   ++KS++
Sbjct:    6 QKIDFAGEESKILKYWDDIKAFETSVKMSEGKPEYSFYDGPPFATGLPHYGHILAGTIKDTITRYAHQTGHHVERRFGWDCHGLPIEFEIDKLHGVRTKEDVLKMGIPTYNQHCRSIVMKYSHEWEIVVNRMGRWIDMKNNYKTMDTPFMESVWWVFQELFKKDLVYQGFKVMPYSIGCTTPLSNFEASSNYKDVSDPACVVSFQTLDDEKVSILAWTTTPWTLPSNLALTVNPKMEYIKINDIKRNQIFILGKNRTSILYKSDK 270          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVK-VRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVR------AVFESHAEMIYRTILQPIIVRNTNSNPNPICE 3240
            G +L   +Y PLF YF +   ET AFR++ D YVT  SGTG+VH AP FGE+D   CL NG+I +   +   +D+ G+FT +V  FEG+YVK ADKLII++L     L      +HSYPFCWRSDTPLL ++VP+WF+RV++IV Q+L +  +++WVP+ +KE RF NW+ +ARDW +SRNRYWGTP+PLWVSDD+EEVVCVGSI ELE L+GV+ + DLHR+ ID + IPSK  KG L+R+ EVFDCWFESGSMPYA  H+PF  + ++F+E  PA+FI+EG+DQTRGWFYTL V+ T +FG  P+KN++ SGIVLA+DG+KMSK LKNYPDP  V+NKYGADALRLY+I+SPV++ +SLKF E GV++++    +PW+NSFKFL    +   +K  N    + F+ +   K++N+MD WI++  QSL++F   +M +Y L TV P+L+ +ID+LTNWY+R NR+RL+GE  +  ED + A+++LF  L+     ++PF PF++E  Y RLK+ +   E    K G D +    SVH++  P   K+     IE +V+ MQ++++LGR IR++KT++LK+PL  +VI+  D   +K +E++++Y++EELNV+ + +++D+ KY VE +A  +  +LG KLKKD + V  A  ++T+EQ+ E+  + K+ + G EL   DL  I  +           E+R+  D +L++MD +   EL  E +ARE++NRIQ+ RK+  L   D V +    E E V+      A+ + H +M+ +T  +  I +   S  +PI +
Sbjct:  282 GSDLVGLKYEPLFPYFAEQFHET-AFRVISDDYVTSDSGTGIVHNAPAFGEEDNAACLKNGVISEDSVLPNAIDDLGRFTKDVPDFEGVYVKDADKLIIKYLTNTGNLLLASQIRHSYPFCWRSDTPLLYRSVPAWFVRVKNIVPQMLDSVMKSHWVPNTIKEKRFANWIANARDWNVSRNRYWGTPIPLWVSDDFEEVVCVGSIKELEELTGVRNITDLHRDVIDKLTIPSKQGKGDLKRIEEVFDCWFESGSMPYASQHYPFE-NTEKFDERVPANFISEGLDQTRGWFYTLAVLGTHLFGSVPYKNVIVSGIVLAADGRKMSKSLKNYPDPSIVLNKYGADALRLYLINSPVLKAESLKFKEEGVKEVVSKVLLPWWNSFKFL-DGQIALLKKMSN----IDFQYDDSVKSDNVMDRWILASMQSLVQFIHEEMGQYKLYTVVPKLLNFIDELTNWYIRFNRRRLKGE--NGVEDCLKALNSLFDALFTFVRAMAPFTPFLSESIYLRLKEYI--PEAVLAKYGKDGR----SVHFLSYPVVKKEYFDEAIETAVSRMQSVIDLGRNIREKKTISLKTPLKTLVILHSDESYLKDVEALKNYIIEELNVRDVVITSDEAKYGVEYKAVADWPVLGKKLKKDAKKVKDALPSVTSEQVREYLESGKLEVAGIELVKGDLNAIRGL--PESAVQAGQETRTDQD-VLIIMDTNIYSELKSEGLARELVNRIQKLRKKCGLEATDDVLV----EYELVKDTIDFEAIVKEHFDMLSKTC-RSDIAKYDGSKTDPIGD 1055          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVE---IVDRVASCN 886
            MSE  N   SF  EE+ +L  W+EI AF T LE +K K ++SF+DGPPFATG PHYGH+LA ++KDIV R+A  T HHVERRFGWD HGVPIE+ IDKKL I G  DV K G+  YNNECRSIVM Y+ DW   + RLGRWIDF  DYKTMYP FMES W+ FKQ+ EKG VYRG KVMP+ST  +TPLSNFEA+QNYKDVNDP+V + F +     T+L+AWTTTPWTLPSNL+LCVN D +YVK+ +    + FI++ES I  ++K  + E   IV+++   +
Sbjct:    1 MSES-NAHFSFPKEEEKVLSLWDEIDAFHTSLELTKDKPEFSFFDGPPFATGTPHYGHILASTIKDIVPRYATMTGHHVERRFGWDTHGVPIEHIIDKKLGITGKDDVFKYGLENYNNECRSIVMTYASDWRKTIGRLGRWIDFDNDYKTMYPSFMESTWWAFKQLHEKGQVYRGFKVMPYSTGLTTPLSNFEAQQNYKDVNDPAVTIGFNVIGQEKTQLVAWTTTPWTLPSNLSLCVNADFEYVKIYDETRDRYFILLESLIKTLYKKPKNEKYKIVEKIKGSD 284          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDN-----QKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNND----------------------NKTTDC--------QYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFES---HAEMIYRTILQPIIV 3204
            G+ L    Y P+F+YF  +K+E  AFR++CD+YVT+ +GTGVV QAPYFGEDD+R+C++NGII K   +VCPVD CG+FT+E+  F GIYVK ADK I   LK++ RL +H T  HSYPFCWRSDTPL+ +A+P+WFIRV+D+VD+LL  NA+ +WVPDFV+E RF NWL+DARDWA+SRNR+WGTP+P+W SDD EEV+CVGSI EL +LSGV++ DLH+ES+D I IPS+  +GVLRRV EVFDCWFESGSMPYAQ H+PF  + K F E FPADFIAEGIDQTRGWFYTL VIST +F K PFK+L+ +GIVLA+DGQKMSKR KNYPDP+EVI+++GADALRLY+I+SPVVR Q+L+F E+GV D++KD F+PW+N+ +FLF SS++P+E+   +G+     P++ P+T N MD+WI+SFTQSLI F   +++EY L TV PRL+K+ID L NWYVRMNR+RL+G+ + ++ DW +A+HTL  V+YQ T+++SPF PFITEF YQRL+ RLDF+       G+          PESVHY+  P+ N +LI P IE++VA MQ  VELGR IR +  L LK+PL E +++  + +  + I S   Y++EELNV+ LT ++DK+KY V+LR +LNHR +G++LKKDY+AV++A K+++T  LE++ +T  IT+ GH L  +DL V+ + + +                      +  T+C         YE+ S   G+LVL+D    +EL  E +AREIINRIQR RK+  LIP+DP+ +   ++S  ++ +       A++I  T+ QP+ V
Sbjct:   23 GKTLNGLTYEPMFDYFAHLKKERRAFRVLCDTYVTDDAGTGVVQQAPYFGEDDFRICMANGIIGKDTPMVCPVDPCGRFTDEIKEFAGIYVKEADKTICSVLKQRGRLLSHNTINHSYPFCWRSDTPLIYRALPTWFIRVQDLVDRLLENNAKCHWVPDFVREGRFANWLRDARDWAVSRNRFWGTPIPIWASDDMEEVICVGSIEELAQLSGVRITDLHKESVDPITIPSRTGRGVLRRVSEVFDCWFESGSMPYAQXHYPFE-NTKTFEEGFPADFIAEGIDQTRGWFYTLLVISTALFNKPPFKHLIVNGIVLAADGQKMSKRAKNYPDPMEVISRHGADALRLYLINSPVVRAQNLRFTEAGVHDVVKDVFLPWYNALRFLFESSIIPYERA--TGQTFKVPPDSVPETVNFMDKWILSFTQSLILFVHQELAEYRLYTVVPRLVKFIDHLVNWYVRMNRRRLKGDAIQNDTDWRAALHTLIKVIYQMTLLMSPFTPFITEFIYQRLRSRLDFTANLTTPSGLPTGYSHVTGAPESVHYLHAPKANNELINPVIEDTVAWMQAAVELGRIIRTRTNLPLKAPLREAIVIHPEPNVRESIRSALVYIVEELNVRILTTTDDKQKYGVQLRGQLNHRTVGIRLKKDYKAVVEAVKSMSTSDLEQYASTGSITVCGHVLSGDDLSVVYSTSGNQEGKPSEPAQGKSEKGKAKKGKDAPTECSTTHEDIQHYEAASDSRGLLVLLDTTPDEELENERLAREIINRIQRTRKKAELIPDDPIVVIVATDSSELQRIASPTALFADLIQATVKQPLNV 835          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKC-----PESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDN------------KTTDCQ--------YESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSES---ESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECSILS 3255
            G++L+  +Y P+F+YF+ +KQE  AFR++CD+YVTE  GTGVVHQAPYFGEDDYRVC ++GII K  +IVCPVD  G FT E+T F G+YVK ADKLI Q+LK++ R+ +  T  HSYPFCWRSDTPL+ KAVP+WFIRVE ++D+LL  N + +WVP+FV+E RF NWL+DARDWA+SRNR+WGTP+PLWVS+D EEVVCVGSI EL +LSGV V DLHRE+ID + IPS+  +GVLRRV EVFDCWFESGSMPYAQVH+PF  + K+F E FPADFIAEGIDQTRGWFYTL V+ST +F K PFK+L+ +GIVLASDGQKMSKRLKNYPDPL+VI ++GADALRLY+I+SPVVR Q+L+F ESGV D++KD F+PW+N+F+FL  SS+VP+E+  ++G+     P++ P+T+N MD WI+SFTQSLI F   +++EY L TV PRL+K+ID L NWYVRMNR+RL+G+   + +DW +A+HTL  VL+Q   +++PF PFITEF YQRL+ R+DF E      G+    C     PESVH++ +P+ NK LI  DIEE+VA MQ  VELGR IR +  L LK+PL E +++  D    K+IES ++Y++EELNV+ LT+++DK++Y V+LR  LNHR+LG +LK+DY++V++  K + + +LE+F  T  IT+ GH L  +DL V+ T +               KT   +        YE+ S   G+LV++D     EL +E +ARE++NRIQR RK+  L+PE+P+ I   ++S   + V +    H  +I  TI QPI V  T   P    E S+  
Sbjct:  287 GKQLEGLKYQPIFDYFVHLKQERNAFRVLCDTYVTEDVGTGVVHQAPYFGEDDYRVCTAHGIIWKDASIVCPVDATGCFTAEITDFAGMYVKEADKLICQNLKKRGRMVHQSTVNHSYPFCWRSDTPLIYKAVPTWFIRVECLIDKLLENNDKCHWVPNFVREGRFANWLRDARDWAVSRNRFWGTPVPLWVSEDLEEVVCVGSIDELAKLSGVTVTDLHRENIDHLTIPSRTGRGVLRRVSEVFDCWFESGSMPYAQVHYPFE-NAKEFAERFPADFIAEGIDQTRGWFYTLLVLSTALFDKPPFKHLIVNGIVLASDGQKMSKRLKNYPDPLDVIQRHGADALRLYLINSPVVRAQNLRFFESGVHDVVKDVFLPWYNAFRFLIESSIVPYER--STGQAFTVTPDSVPQTDNFMDRWILSFTQSLILFVHTELAEYRLYTVVPRLVKFIDHLVNWYVRMNRRRLKGDAAKNEDDWRAALHTLIHVLFQMICLLAPFTPFITEFLYQRLRSRIDFKENLKDHAGLPIGYCRQTGAPESVHFLPVPQANKALIFTDIEETVAWMQATVELGRIIRTRVNLPLKAPLHEAIVIQSDPVVRKQIESAKAYIVEELNVRILTVTDDKERYGVQLRGVLNHRVLGSRLKQDYKSVVETVKNMPSSELEKFVQTGSITVCGHVLNEDDLSVVYTTSGGGVAEGEKKAKVAAKTEQVKTGAAVTQRYETASDARGLLVILDTTADPELEEERLARELVNRIQRTRKKAQLVPENPIVIVVSTDSTVLQRVASPTSKHMPLIQSTIKQPITVTPTRIGPTGDQELSVFG 1106          

Query:   62 AISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDP-----------SVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEIVD 868
            +++  +EE +I++YW + K F+TCL+QS ++ +Y+FYDGPPFATG+PHYGHLLAG++KDI+ R+AHQ+  HV+RRFGWDCHG+P+EYE+DK+  I GP DV KMGI AYN++CR+IVMKYS+ WE +  RLGRWIDF+ DY+TMYPWFMESVW++FKQ+F+KGLVYRGVKVMPFSTAC+TPLSNFEA QNY+DV DP           +VIV+FPL D    EL+AWTTTPWTL SNLALCV+PD +YVK+ + +  + FI+M +R+  +++    EI++
Sbjct:    4 SVNLPEEEVIIIEYWEKQKIFQTCLKQSSNRPRYTFYDGPPFATGLPHYGHLLAGTIKDIIPRYAHQSGFHVDRRFGWDCHGLPVEYEVDKEYGITGPDDVAKMGIKAYNDKCRAIVMKYSEQWEHVTRRLGRWIDFENDYRTMYPWFMESVWWVFKQLFDKGLVYRGVKVMPFSTACATPLSNFEAGQNYRDVQDPASKIENSYLIHAVIVSFPLDDHPDVELVAWTTTPWTLVSNLALCVHPDKEYVKLYDKQLKRTFILMNARLPILYRDTGYEIIE 283          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKC-----PESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNN------------DNKTTDCQ--------YESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAE---MIYRTILQPI--------------------------------IVRNTNSNPNPICECSILSDTSGTSSEVKDSILSMWFTHDHNRLKTDNRKCLPKSSNVEVI--CDGDLNSVV----QLDVMGIDSWDELLRHVRVAFEW 3477
            G+EL+  +Y P+F+YF+ +K+E  AFR++CD+YVTE  GTG+VHQAPYFGEDDYRVC  +GII K  +IVCPVD  G FT E++ F G+YVK ADKLI Q+LK++ R+ +  T  HSYPFCWRSDTPL+ KAVP+WFIRVE ++D+LL  N + +WVP+FV+E RF NWL+DARDWA+SRNR+WGTP+PLWVS+D EEVVC+GSI EL +LSGV V DLHRE+ID + IPS+  +GVLRRV EVFDCWFESGSMPYAQVH+PF  + K+F E FPADFIAEGIDQTRGWFYTL V+ST +F K PFK+L+ +GIVLASDGQKMSKRLKNYPDPL+VI ++GADALRLY+I+SPVVR Q+L+F ESGV D++KD F+PW+N+F+FL  SS+VP+E+  ++G+     P++ P+T+N MD WI+SFTQSLI F   +++EY L TV PRL+K+ID L NWYVRMNR+RL+G+   + +DW +A+HTL  VL+Q   +++PF PFITEF YQRL+ R+DF E      G+    C     PESVH++  P+ NK LI  DIEE+VA MQ  VELGR IR +  L LK+PL E +++  D    K+IES ++Y++EELNV+ LT+++DK++Y V+LR  LNHR+LG +LK+DY++V++  K + + +LE+F  T  IT+ GH L  ++L V+ T +             + KT   +        YE+ S   G+LV++D     EL +E +ARE++NRIQR RK+  L+PE+P+ I   ++S  ++ V    ++   +I  TI QPI                                I+R T S P    E  + S T G+S   K +      +H H              ++V+VI    G   SV+    Q +++  DS D+LLR +R  F W
Sbjct:  282 GKELEGLKYKPIFDYFVHLKEERNAFRVLCDTYVTEDVGTGIVHQAPYFGEDDYRVCTVHGIIWKDASIVCPVDATGCFTAEISDFAGMYVKEADKLICQNLKKRGRMVHQSTVNHSYPFCWRSDTPLIYKAVPTWFIRVECLIDKLLENNDKCHWVPNFVREGRFANWLRDARDWAVSRNRFWGTPVPLWVSEDLEEVVCIGSIDELAKLSGVTVTDLHRENIDHLTIPSRTGRGVLRRVSEVFDCWFESGSMPYAQVHYPFE-NAKEFAERFPADFIAEGIDQTRGWFYTLLVLSTALFDKPPFKHLIVNGIVLASDGQKMSKRLKNYPDPLDVIQRHGADALRLYLINSPVVRAQNLRFFESGVHDVVKDVFLPWYNAFRFLIESSIVPYER--STGQAFTVTPDSVPQTDNFMDRWILSFTQSLILFVHTELAEYRLYTVVPRLVKFIDHLVNWYVRMNRRRLKGDAAKNEDDWRAALHTLIHVLFQMICLLAPFTPFITEFLYQRLRSRIDFKENLKDHAGLPIGYCRETGAPESVHFLPFPQANKTLIFTDIEETVAWMQATVELGRIIRTRVNLPLKAPLHEAIVIQSDPTIRKQIESAKAYIVEELNVRILTVTDDKERYGVQLRGVLNHRVLGSRLKQDYKSVVETVKNMPSSELEKFVQTGSITVCGHVLNEDELSVVYTTSGSGVAEGEKKAKVEAKTEQVKTGPAVTQRYETASDARGLLVILDTTADPELEEERLARELVNRIQRTRKKAQLVPENPIVIVVSTDSTVLQRVASPTSKLMPLIQSTIKQPITVTPTRIGPTGDQELSVFGWAALPSGWTLGAEIIRETVSIPPDDFELVLFSRTDGSSGPSKTTPAIPVLSHPHG----------AADAHVDVIHRLTGKKCSVMLSDSQSNLLVTDS-DDLLRKIRCVFGW 1202          

Query:   41 MSEF--FNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEIVD 868
            MSE      +++F +EE +IL+YW + K F+TCL+QS ++ +Y+FYDGPPFATG+PHYGHLLAG++KDI+ R+AHQ+  HV+RRFGWDCHG+P+EYE+DK+  I GP DV KMGI AYN++CR+IVMKYS+ WE +  RLGRWIDF+ DY+TMYPWFMESVW++FKQ+F+KGLVYRGVKVMPFSTAC+TPLSNFEA QNY+DV DP++IV+FPL D    EL+AWTTTPWTL SNLALCV+PD +YVK+ + +  + FI+M +R+  +++    EI++
Sbjct:    1 MSEISQLPASVNFPEEEVVILEYWEKQKIFQTCLKQSSNRPRYTFYDGPPFATGLPHYGHLLAGTIKDIIPRYAHQSGFHVDRRFGWDCHGLPVEYEVDKEYGITGPDDVAKMGIKAYNDKCRAIVMKYSEQWEHVTRRLGRWIDFENDYRTMYPWFMESVWWVFKQLFDKGLVYRGVKVMPFSTACATPLSNFEAGQNYRDVQDPAIIVSFPLDDHPDVELVAWTTTPWTLVSNLALCVHPDKEYVKLYDKQLKRTFILMSARLPILYRDTGYEIIE 278          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWS--ESESVRAVFESHAEMIYRTI 3186
            G  L+ K+Y PLFEYFI+ K + GAF ++ DSYV E  GTGVVHQAPYFG DDYRVC+   II+K    VCPVD  G FT EVT F G YVK ADK II+ LKEK RL +  + KHSYPFCWRSDTPL+ KAVPSWF+RVE +V++LL  NA+ YWVPDFV+E RF NWLKDARDWAISRNRYWGTP+PLWVSDD+EEVVC+GS+AELE LSGVKV DLHRESID + IPS+  KG+L RVPEVFDCWFESGSMPYAQVH+PF  + K+  + FPADFIAEGIDQTRGWFYTL V+ST +FG+ PFKN++ +G+VLASDGQKMSKR KNYPDP+ ++N YGADALRLY+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL  +  V   + ++ GR  L+  NT  ++NN+MD+WI+SFTQSLIKFF+ +M+ Y L TV PRL+K++D LTNWYVRMNR+RL+GE  S  ED I A+ TLF VL+    +++P+ PFITE  YQ LK  +D + +         +K  ES+HY+M+P+  +DLI   IE +V+ +Q+++ELGR IRD+KT+ +K PL EVV++ QD ++++ I S+E YVLEELNV+++TLS +K KY V LRAE +H +LG +LK  ++ V+ A K L +EQLEEFQ T  I + GHEL  EDL ++ T +     +  Q+E+ S    +LVL+D      ++ E VARE+INRIQ+ RK+ NL+P D +T+Y  S  E + +  V + H + I+ TI
Sbjct:   92 GIALKGKKYKPLFEYFIQCK-DKGAFAVVVDSYVKEEEGTGVVHQAPYFGADDYRVCMDFNIIQKDSVPVCPVDASGCFTAEVTDFVGQYVKDADKNIIKLLKEKGRLVHSSSFKHSYPFCWRSDTPLIYKAVPSWFVRVEHMVEKLLENNAQCYWVPDFVREKRFGNWLKDARDWAISRNRYWGTPIPLWVSDDFEEVVCIGSMAELEELSGVKVTDLHRESIDHLTIPSRCGKGLLHRVPEVFDCWFESGSMPYAQVHYPFE-NRKELEDAFPADFIAEGIDQTRGWFYTLLVLSTALFGRPPFKNVIVNGLVLASDGQKMSKRKKNYPDPMSIVNSYGADALRLYLINSPVVRAENLRFKEEGVRDILKDVFLPWYNAYRFLVQN--VQILQHKDEGREFLYNENTLKESNNVMDKWILSFTQSLIKFFKAEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGE--SGTEDCIMALETLFSVLFSMCRLMAPYTPFITELMYQNLKTLIDPASV--------QEKNTESIHYLMLPQVREDLINKKIESAVSCLQSVIELGRVIRDRKTIPVKYPLKEVVVIHQDPEALENIRSLEKYVLEELNVRQVTLSTNKDKYGVRLRAEPDHMVLGKRLKGAFKLVMAAIKELKSEQLEEFQETGTIVVEGHELHGEDLRLMYTFDQVAGGS-AQFEAHSDAQ-VLVLLDVTPDQSMVDEGVAREVINRIQKLRKKRNLVPTDEITVYYRSHPEGDYLDTVIKEHRDFIFATI 849          

Query:  632 YKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKV--KEVKTGKLFIIMESRIGYVFKSN-QVEIVDR 871
            +KDV DPSV V+FPL +D+S  L+AWTTTPWTLPSNLALCVNP+L YVK+  K   TGK++I+MESR+  ++KS+ + EI+DR
Sbjct:    1 FKDVQDPSVTVSFPLDEDASVSLVAWTTTPWTLPSNLALCVNPELQYVKLRGKYNATGKIYILMESRLIALYKSDSEYEILDR 83          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESES--VRAVFESHAEMIYRTILQPI 3198
            G  L+ K+Y PLFEYFI+ K + GAF ++ D+YV E  GTGVVHQAPYFG DDYRVC+   II+K    VCPVD  G FT EVT F G YVK ADK II+ LKEK RL +  + KHSYPFCWRSDTPL+ KAVPSWF+RVE +V++LL  NA+ YWVPDFV+E RF NWLKDARDWAISRNRYWGTP+PLWVSDD+EEVVC+GS+ ELE LSGVKV DLHRESID + IPS+  KG+L RVPEVFDCWFESGSMPYAQVH+PF    K+  + FPADFIAEGIDQTRGWFYTL V+ST +FG+ PFKN++ +G+VLASDGQKMSKR KNYPDP+ ++N YGADALRLY+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL  +  V   + ++ GR  LF  NT  ++NN+MD+WI+SFTQSLI+FF+ +M+ Y L TV PRL+K++D LTNWYVRMNR+RL+GE  +  ED I A+ TLF VL+    +++P+ PFITE  YQ LK  +D + +         +K  ES+HY+M+P+  +DLI   IE +V+ +Q+++ELGR IRD+KT+ +K PL EVV++ QD ++++ + S+E Y+LEELNV+++TLS +K KY V+LRAE +H +LG +LK  ++ V+ A K L +EQLEEFQ T  I + GHEL +EDL ++ T +     +  QYE+ S    +LVL+D      ++ E VARE+INRIQ+ RK+ NL+P D +T+Y  ++ E   +  V + H + I+ TI  P+
Sbjct:  281 GGVLKGKKYKPLFEYFIQCK-DKGAFTVVVDNYVKEEEGTGVVHQAPYFGADDYRVCMDFNIIQKDSVPVCPVDASGCFTAEVTDFAGQYVKDADKNIIKLLKEKGRLVHSSSFKHSYPFCWRSDTPLIYKAVPSWFVRVEHMVEKLLENNAQCYWVPDFVREKRFGNWLKDARDWAISRNRYWGTPIPLWVSDDFEEVVCIGSMGELEELSGVKVTDLHRESIDHLTIPSRCGKGLLHRVPEVFDCWFESGSMPYAQVHYPFENK-KELEDAFPADFIAEGIDQTRGWFYTLLVLSTALFGRPPFKNVIVNGLVLASDGQKMSKRKKNYPDPMSIVNSYGADALRLYLINSPVVRAENLRFKEEGVRDILKDVFLPWYNAYRFLVQN--VQILQHKDEGREFLFNENTVKESNNIMDKWILSFTQSLIQFFKAEMAAYRLYTVVPRLVKFVDILTNWYVRMNRRRLKGE--NGTEDCIMALETLFSVLFSMCRLMAPYTPFITELMYQNLKTLIDPASV--------QEKNTESIHYLMLPQVREDLIDKKIESAVSCLQSVIELGRVIRDRKTIPVKYPLKEVVVIHQDPEALENVRSLEKYILEELNVRQVTLSTNKDKYGVQLRAEPDHMVLGKRLKGAFKLVMAAIKELKSEQLEEFQETGTIVVEGHELHTEDLRLMYTFDQVAGGS-AQYEAHSDAQ-VLVLLDVTPDQSMVDEGVAREVINRIQKLRKKRNLVPTDEITVYYRAQPEGDYLDTVIKEHTDFIFATIKAPL 1042          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSN-QVEIVDR 871
            M +   E I+F +EE+ IL+ W  +  F+ CL+QSK + +++FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YNN+CR IVM+YS++W+  V+RLGRWIDF+ DYKT+YP FMESVW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSV+V+FPL +D S  L+AWTTTPWTLPSNLALCVNP+L Y+K+++  TGK++I+MESR+  ++KS+ + E++DR
Sbjct:    1 MVQQVPENITFPNEEEKILELWKNLNCFQECLKQSKSRPRFNFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIKEYNNQCRGIVMRYSKEWQSSVTRLGRWIDFENDYKTLYPEFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVVVSFPLDEDESVSLVAWTTTPWTLPSNLALCVNPELQYIKLRDNATGKIYILMESRLIALYKSDSEYEVLDR 278          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSE--SESVRAVFESHAEMIYRTILQPI 3198
            G+ L+ K+Y PLF+YF K + E+GAF ++ D+YV E  GTGVVHQAPYFG DD+RVC+   II++    +CPVD  G+FT +VTHF G YVK ADK II+ LKE  RL N  + KHSYPFCWRSDTPL+ KAVPSWF+RVE +V++LL  N + YWVP+FV+E RF NWL+DARDWAISRNRYWGTP+PLWVSDD+EEVVCVGS+AELE L+GVKV DLHRESID + IPS+  KG L+RV EVFDCWFESGSMPYAQVH+PF  + ++F + FPADFIAEGIDQTRGWFYTL V+ST +FGK PFKN++ +G+VLASDGQKMSKR KNYPDP  ++  YGADALRLY+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL   ++    K+++     L+  NT   ++N+MD+WI SFTQSLI+FF+ +M  Y L TV P+L+K++D LTNWYVR NR+RL+GE  S  ED + A+ TLF VL+    +++PF P+ITE  YQ L+  +D + ++        +K   S+HY+M+P   + LI   IE +V+ MQ+++ELGR IRD+KTL +K PL EVV++ QD ++++ I+S++ Y+LEELNV++LTLS DK KY + LRAE +H +LG +LK  +++V  + K L +EQLE FQ T  I + GHEL  EDL ++ T +  + +   QYE+ S    +LVL+D      L+ E VARE+INR+Q+ RK+ +L+P D +T+Y  SE   + +  V ++H + +  T   P+
Sbjct:  281 GKTLKGKKYKPLFDYFSKCR-ESGAFSVVLDNYVREEEGTGVVHQAPYFGADDFRVCMEYNIIQRDSVPICPVDSSGRFTPDVTHFSGQYVKDADKNIIKWLKENGRLVNASSFKHSYPFCWRSDTPLIYKAVPSWFVRVEHMVEKLLENNDKCYWVPEFVREKRFGNWLRDARDWAISRNRYWGTPIPLWVSDDFEEVVCVGSMAELEELTGVKVTDLHRESIDSLTIPSRCGKGQLKRVSEVFDCWFESGSMPYAQVHYPFE-NRREFEDTFPADFIAEGIDQTRGWFYTLLVLSTALFGKPPFKNVIVNGLVLASDGQKMSKRKKNYPDPGIIVQSYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVFLPWYNAYRFLVQ-NVQRLHKEEDIQ--FLYNENTARPSDNIMDKWIQSFTQSLIQFFKEEMDAYRLYTVVPKLVKFVDMLTNWYVRTNRRRLKGE--SGTEDCVWALETLFSVLFSMCRLMAPFTPYITEMMYQNLRHLIDPASVE--------EKDSSSIHYLMLPNVRESLIDKRIESAVSQMQSVIELGRVIRDRKTLPVKYPLREVVVIHQDPEALRDIQSLQKYILEELNVRQLTLSTDKDKYGIRLRAEPDHMVLGKRLKGAFKSVTASIKELKSEQLEVFQKTGTIVVDGHELHEEDLRLMYTFDQTSGSA-AQYEAHSDAQ-VLVLLDFTPDQSLVDEGVAREVINRVQKLRKKGHLVPSDEITVYYSSEPAGDYLDKVIQAHTDFVLATTKAPL 1041          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDR 871
            M E   E+I+F  EE+ IL++W E   F+ CL+QSK++ KY+FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CRSIVM+YS++WE+ V+R+GRWIDFK DYKT+YPWFME+VW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSVIV FPL +D S  L+AWTTTPWTLPSNLALCVNP+  YVKVK+  T K++I+ME+R+G +FKS ++  I+D+
Sbjct:    1 MVEPVPESINFPSEEERILQFWKEKDCFQECLKQSKNRPKYTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIEEYNKQCRSIVMRYSREWEESVTRMGRWIDFKHDYKTLYPWFMETVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVIVNFPLLEDESVCLIAWTTTPWTLPSNLALCVNPEFLYVKVKDNTTDKVYIMMEARLGALFKSESEYTILDK 278          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSE--SESVRAVFESHAEMIYRTILQPI 3198
            G+ L+ K+Y PLF+YF K + E+GAF ++ D+YV E  GTGVVHQAPYFG DD+RVC+   II++    +CPVD  G+FT +VTHF G YVK ADK II+ LKE  RL N  + KHSYPFCWRSDTPL+ KAVPSWF+RVE +V++LL  N + YWVP+FV+E RF NWL+DARDWAISRNRYWGTP+PLWVSDD+EEVVCVGS+AELE L+GVKV DLHRESID + IPS+  KG L+RV EVFDCWFESGSMPYAQVH+PF  + ++F + FPADFIAEGIDQTRGWFYTL V+ST +FGK PFKN++ +G+VLASDGQKMSKR KNYPDP  ++  YGADALRLY+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL   ++    K+++     L+  NT   ++N+MD+WI SFTQSLI+FF+ +M  Y L TV P+L+K++D LTNWYVR NR+RL+GE  S  ED + A+ TLF VL+    +++PF P+ITE  YQ L+  +D + ++        +K   S+HY+M+P   + LI   IE +V+ MQ+++ELGR IRD+KTL +K PL EVV++ QD ++++ I+S++ Y+LEELNV++LTLS DK KY + LRAE +H +LG +LK  +++V  + K L +EQLE FQ T  I + GHEL  EDL ++ T +  + +   QYE+ S    +LVL+D      L+ E VARE+INR+Q+ RK+ +L+P D +T+Y  SE   + +  V ++H + +  T   P+
Sbjct:  281 GKTLKGKKYKPLFDYFSKCR-ESGAFSVVLDNYVREEEGTGVVHQAPYFGADDFRVCMEYNIIQRDSVPICPVDSSGRFTPDVTHFSGQYVKDADKNIIKWLKENGRLVNASSFKHSYPFCWRSDTPLIYKAVPSWFVRVEHMVEKLLENNDKCYWVPEFVREKRFGNWLRDARDWAISRNRYWGTPIPLWVSDDFEEVVCVGSMAELEELTGVKVTDLHRESIDSLTIPSRCGKGQLKRVSEVFDCWFESGSMPYAQVHYPFE-NRREFEDTFPADFIAEGIDQTRGWFYTLLVLSTALFGKPPFKNVIVNGLVLASDGQKMSKRKKNYPDPGIIVQSYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVFLPWYNAYRFLVQ-NVQRLHKEEDIQ--FLYNENTARPSDNIMDKWIQSFTQSLIQFFKEEMDAYRLYTVVPKLVKFVDMLTNWYVRTNRRRLKGE--SGTEDCVWALETLFSVLFSMCRLMAPFTPYITEMMYQNLRHLIDPASVE--------EKDSSSIHYLMLPNVRESLIDKRIESAVSQMQSVIELGRVIRDRKTLPVKYPLREVVVIHQDPEALRDIQSLQKYILEELNVRQLTLSTDKDKYGIRLRAEPDHMVLGKRLKGAFKSVTASIKELKSEQLEVFQKTGTIVVDGHELHEEDLRLMYTFDQTSGSA-AQYEAHSDAQ-VLVLLDFTPDQSLVDEGVAREVINRVQKLRKKGHLVPSDEITVYYSSEPAGDYLDKVIQAHTDFVLATTKAPL 1041          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDR 871
            M E   E+I+F  EE+ IL++W E   F+ CL+QSK++ KY+FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CRSIVM+YS++WE+ V+R+GRWIDFK DYKT+YPWFME+VW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSVIV FPL +D S  L+AWTTTPWTLPSNLALCVNP+  YVKVK+  T K++I+ME+R+G +FKS ++  I+D+
Sbjct:    1 MVEPVPESINFPSEEERILQFWKEKDCFQECLKQSKNRPKYTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIEEYNKQCRSIVMRYSREWEESVTRMGRWIDFKHDYKTLYPWFMETVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVIVNFPLLEDESVCLIAWTTTPWTLPSNLALCVNPEFLYVKVKDNTTDKVYIMMEARLGALFKSESEYTILDK 278          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSE--SESVRAVFESHAEMIYRTILQPI 3198
            G+ L+ K+Y PLF+YF K + E+GAF ++ D+YV E  GTGVVHQAPYFG D                                         ADK II+ LKE  RL N  + KHSYPFCWRSDTPL+ KAVPSWF+RVE +V++LL  N + YWVP+FV+E RF NWL+DARDWAISRNRYWGTP+PLWVSDD+EEVVCVGS+AELE L+GVKV DLHRESID + IPS+  KG L+RV EVFDCWFESGSMPYAQVH+PF  + ++F + FPADFIAEGIDQTRGWFYTL V+ST +FGK PFKN++ +G+VLASDGQKMSKR KNYPDP  ++  YGADALRLY+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL   ++    K+++     L+  NT   ++N+MD+WI SFTQSLI+FF+ +M  Y L TV P+L+K++D LTNWYVR NR+RL+GE  S  ED + A+ TLF VL+    +++PF P+ITE  YQ L+  +D + ++        +K   S+HY+M+P   + LI   IE +V+ MQ+++ELGR IRD+KTL +K PL EVV++ QD ++++ I+S++ Y+LEELNV++LTLS DK KY + LRAE +H +LG +LK  +++V  + K L +EQLE FQ T  I + GHEL  EDL ++ T +  + +   QYE+ S    +LVL+D      L+ E VARE+INR+Q+ RK+ +L+P D +T+Y  SE   + +  V ++H + +  T   P+
Sbjct:  281 GKTLKGKKYKPLFDYFSKCR-ESGAFSVVLDNYVREEEGTGVVHQAPYFGAD-----------------------------------------ADKNIIKWLKENGRLVNASSFKHSYPFCWRSDTPLIYKAVPSWFVRVEHMVEKLLENNDKCYWVPEFVREKRFGNWLRDARDWAISRNRYWGTPIPLWVSDDFEEVVCVGSMAELEELTGVKVTDLHRESIDSLTIPSRCGKGQLKRVSEVFDCWFESGSMPYAQVHYPFE-NRREFEDTFPADFIAEGIDQTRGWFYTLLVLSTALFGKPPFKNVIVNGLVLASDGQKMSKRKKNYPDPGIIVQSYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVFLPWYNAYRFLVQ-NVQRLHKEEDIQ--FLYNENTARPSDNIMDKWIQSFTQSLIQFFKEEMDAYRLYTVVPKLVKFVDMLTNWYVRTNRRRLKGE--SGTEDCVWALETLFSVLFSMCRLMAPFTPYITEMMYQNLRHLIDPASVE--------EKDSSSIHYLMLPNVRESLIDKRIESAVSQMQSVIELGRVIRDRKTLPVKYPLREVVVIHQDPEALRDIQSLQKYILEELNVRQLTLSTDKDKYGIRLRAEPDHMVLGKRLKGAFKSVTASIKELKSEQLEVFQKTGTIVVDGHELHEEDLRLMYTFDQTSGSA-AQYEAHSDAQ-VLVLLDFTPDQSLVDEGVAREVINRVQKLRKKGHLVPSDEITVYYSSEPAGDYLDKVIQAHTDFVLATTKAPL 1000          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDR 871
            M E   E+I+F  EE+ IL++W E   F+ CL+QSK++ KY+FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  HV+RRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CRSIVM+YS++WE+ V+R+GRWIDFK DYKT+YPWFME+VW++FKQ+++KGLVYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSVIV FPL +D S  L+AWTTTPWTLPSNLALCVNP+  YVKVK+  T K++I+ME+R+G +FKS ++  I+D+
Sbjct:    1 MVEPVPESINFPSEEERILQFWKEKDCFQECLKQSKNRPKYTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIEEYNKQCRSIVMRYSREWEESVTRMGRWIDFKHDYKTLYPWFMETVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVIVNFPLLEDESVCLIAWTTTPWTLPSNLALCVNPEFLYVKVKDNTTDKVYIMMEARLGALFKSESEYTILDK 278          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTN--EVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARD-WAISRNRYWGTPLPLWVSDDY-EEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVL------RRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFP-ADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVIN---------KYGADALRLYMISSPVVRGQSL--KFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQ-LTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQ 2397
            ++  ++VT + GTG+VH AP  G +DY V     +      + C VDE GKFT    V   E    +     +I  L+    L       HSYP+ WRS  P++ +A   WFI    + D+      +   +P+  + +     + D R  W ISR R WG P+P++      E ++   ++A + ++   K  D   E   + ++P  + K V        R  +V D WF+SG+  +A V            E  P AD   EG DQ  GWF +  + S  +  KAP+K LV  G  L+  G+KMSK L N  DP  VIN          YGAD LR ++  S V     +  K + S   ++ K       N+ KFL   +L  F+ +  +           PK  + +D++++   +          +E+    V   L  +I + L+N+Y  + + RL  +  +S     S    L  +L   T  I+P +P + E  YQ
Sbjct:  357 LLPANHVTMAKGTGLVHTAPAHGMEDYSVATHFQL-----PVECMVDEEGKFTELAGVDLQEQSVFEEGTSTVISMLRAAGALVKEEECVHSYPYDWRSKKPVIIRASKQWFINTASLKDKAKEVLQKVRVMPESARASLLA--MLDRRTYWCISRQRSWGVPIPVFYHKQTGEPLINKHTVAHIAKVFAEKGSDSWWEEPIETLLPPDVLKKVTGAVTDYERGEDVLDIWFDSGTS-WAAV----------LQEAEPRADVYVEGKDQIGGWFQSSLLTSVAVRNKAPYKALVVHGFALSEKGEKMSKSLGNVVDPDVVINGGTDKAASPAYGADVLRWWVAESNVFSEVQIGPKALNSARENINK-----LRNTLKFLL-GNLQGFDPRTQA---------VDPKEMHYIDQYLLHLLREYSIKVTDAYNEFDCGRVIRLLQAFITRDLSNFYFSIIKDRLYCDAENSVGR-RSCQTALEEILDGVTRSIAPILPHLAEEVYQ 827          

Query:   17 NYFKIKLDMSEFFNEAISFADEEKLILKY-WNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPL 676
            + F +KL   E  N  +    E      Y W           + K KK++  +DGPP+A G  H GH L   +KDI  RF       V    GWDCHG+PIE      L   G      M       + R    +          R G   D++  Y T    +  +   +F+ +  KGL+Y+  K + +S +  T L+  E + N + V+  +V  TFPL
Sbjct:   68 SAFPMKLSGPELLNLELRIQQECSFEQLYSWQR---------ERKAKKEFCLHDGPPYANGDAHVGHALNKILKDIHNRFEMLRGRKVHYVPGWDCHGLPIE------LKALGELQAKDMTPLQIRQKAREFAEEAIARQRAAFQRWGVMADWENCYYTFNGQYEAAQLRVFEDMHSKGLIYQDYKPVFWSPSTRTALAEAELEYNSEHVSK-AVYATFPL 272          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTN--EVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARD-WAISRNRYWGTPLPLWVSDDY-EEVVCVGSIAELERLSGVKVRD-LHRESIDDIIIPSKMNK---GVL---RRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFP-ADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVIN---------KYGADALRLYMISSPVVRGQSLKFVESGVRDM--IKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQ-LTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQ 2397
            ++  ++VT + GTG+VH AP  G +DY V     +      + C VDE GKFT    V   E    +     +I  L+    L       HSYP+ WRS  P++ +A   WFI    + D+      +   +P+  + +     + D R  W ISR R WG P+P++      E ++   ++A + ++   K  D    E I+ ++ P  + K   G +    R  +V D WF+SG+  +A V            E  P AD   EG DQ  GWF +  + S  +  KAP+K LV  G  L+  G+KMSK L N  DP  VIN          YGAD LR ++  S V        V+ G + +   ++      N+ KFL   +L  F+ +  +           PK  + +D++++   +          +E+    V   L  +I + L+N+Y  + + RL  +  +S     S    L  +L   T  I+P +P + E  YQ
Sbjct:  373 LLPANHVTMAKGTGLVHTAPAHGMEDYSVATHFQL-----PVECMVDEEGKFTELAGVDLQEQSVFEEGTSTVISMLRAAGALVKEEECVHSYPYDWRSKKPVIIRASKQWFINTASLKDKAKEVLQKVRVMPESARASLLA--MLDRRTYWCISRQRSWGVPIPVFYHKQTGEPLINKHTVAHIAKVFAEKGSDSWWEEPIETLLPPDVLKKSKAGAVTDYERGEDVLDIWFDSGTS-WAAV----------LQEAEPRADVYVEGKDQIGGWFQSSLLTSVAVRNKAPYKALVVHGFALSEKGEKMSKSLGNVVDPDVVINGGTDKAASPAYGADVLRWWVAESNV-----FSEVQIGPKALNSARENINKLRNTLKFLL-GNLQGFDPRTQA---------VDPKEMHYIDQYLLHLLREYSIKVTDAYNEFDCGRVIRLLQAFITRDLSNFYFSIIKDRLYCDAENSVGR-RSCQTALEEILDGVTRSIAPILPHLAEEVYQ 844          

Query:   14 HNYFKIKLDMSEFFNEAISFADEEKLILKY-WNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXX-----------SNLALCVNPDLDYVKVKEVKTGKLFIIMESRI 829
             + F +KL   E  N  +    E      Y W           + K KK++  +DGPP+A G  H GH L   +KDI  RF       V    GWDCHG+PIE      L   G      M       + R    +          R G   D++  Y T    +  +   +F+ +  KGL+Y+  K + +S +  T L+  E + N + V+  +V  TFPL                              +N A+C  P   Y  VK     +L ++   RI
Sbjct:   67 RSAFPMKLSGPELLNLELRIQQECSFEQLYSWQR---------ERKAKKEFCLHDGPPYANGDAHVGHALNKILKDIHNRFEMLRGRKVHYVPGWDCHGLPIE------LKALGELQAKDMTPLQIRQKAREFAEEAIARQRAAFQRWGVMADWENCYYTFNGQYEAAQLRVFEDMHSKGLIYQDYKPVFWSPSTRTALAEAELEYNSEHVSK-AVYATFPLTTPPPKLAAGLEAADKVSVLVWTTQPWTIPANQAICFMPKAQYSLVKRADNEQLLLVATERI 334          

Query:   59 EAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYK 637
            E I+FA+EE+ IL  W E+ AF+  L+QSK + +Y+FYDGPPFATG+PHYGH+LAG++KD+VTRFAHQ+  HV+RRFGWDCHG+P+EYEIDK LNI+GP DV KMGI  YNN+CR+IVM+Y+++WE  V RLGRWIDFK DYKT+YP FME+VW++F+Q+F+KG VY GVKVMP+STAC+TPLSNFEA QNYK
Sbjct:    7 EKINFAEEEERILALWTELDAFQESLKQSKSRPQYTFYDGPPFATGLPHYGHILAGTIKDVVTRFAHQSGFHVDRRFGWDCHGLPVEYEIDKMLNIKGPEDVAKMGIVEYNNQCRNIVMRYAKEWETTVIRLGRWIDFKNDYKTLYPSFMETVWWVFRQLFDKGFVYSGVKVMPYSTACTTPLSNFEANQNYK 199          

Query:  137 EQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEI-------DKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKD-YKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRD-----------DSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRI 829
            ++ K KK++  +DGPP+A G PH GH+L   +KDI  R+     + V    GWDCHG+PIE +        DK L+   P D+ K        + R    K  +       R G   ++K D Y T    +      +F  + EKG +Y+  K + +S +  T L+  E + N    +  +V V FPL             D++  L+ WTT PWTLP+N A+C  P+  Y  VK  +TG+L ++   R+
Sbjct:   88 KERKSKKEFCLHDGPPYANGDPHVGHVLNKVLKDITNRYYVMRGYKVHFVPGWDCHGLPIELKALTESEVNDKTLS---PLDIRK--------KAREFAEKAIEKQRASFIRWGIMANWKDDCYSTFSKEYEAEQLKVFYNMHEKGFIYQDYKPVFWSPSTRTALAEAELEYNPAHTSK-AVHVKFPLAQVPPKLASLLGPDATVSLVIWTTQPWTLPANEAVCFMPNSTYSVVKCGQTGELLLLAADRV 325          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEV-THFEGIYV---KTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEE 1464
            ++  ++VT   GTG+VH AP  G DD+ V +++ +      +   VDE G FT E     +G  V         ++  L+    L +     HSYPF WRS  P+L +A   WFI  + + D+      +   VP           L     W ISR R WG P+P++      E
Sbjct:  364 LLPAAHVTMLMGTGLVHTAPAHGADDFSVAVAHKL-----PVRSLVDEEGLFTAEAGEELQGKAVLEEGNEAASVVAQLRAAGCLLHEAACVHSYPFDWRSHQPVLVRASSQWFINTDTLRDRAQEVLKKVKVVPS-ASSGGVQAALDRRSFWCISRQRCWGVPIPVFYDRQTRE 532          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVK-VRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVR------AVFESHAEMIYRTILQPIIVRNTNSNPNPICE 3240
            G +L   +Y PLF YF +   ET AFR++ D YVT  SGTG+VH AP FGE+D   CL NG+I +   +   +D+ G+FT +V  FEG+YVK ADKLII++L     L      +HSYPFCWRSDTPLL ++VP+WF+RV++IV Q+L +  +++WVP+ +KE RF NW+ +ARDW +SRNRYWGTP+PLWVSDD+EEVVCVGSI ELE L+GV+ + DLHR+ ID + IPSK  KG L+R+ EVFDCWFESGSMPYA  H+PF  + ++F+E  PA+FI+EG+DQTRGWFYTL V+ T +FG  P+KN++ SGIVLA+DG+KMSK LKNYPDP  V+NKYGADALRLY+I+SPV++ +SLKF E GV++++    +PW+NSFKFL    +   +K  N    + F+ +   K++N+MD WI++  QSL++F   +M +Y L TV P+L+ +ID+LTNWY+R NR+RL+GE  +  ED + A+++LF  L+     ++PF PF++E  Y RLK+ +   E    K G D +    SVH++  P   K+     IE +V+ MQ++++LGR IR++KT++LK+PL  +VI+  D   +K +E++++Y++EELNV+ + +++D+ KY VE +A  +  +LG KLKKD + V  A  ++T+EQ+ E+  + K+ + G EL   DL  I  +           E+R+  D +L++MD +   EL  E +ARE++NRIQ+ RK+  L   D V +    E E V+      A+ + H +M+ +T  +  I +   S  +PI +
Sbjct:  282 GSDLVGLKYEPLFPYFAEQFHET-AFRVISDDYVTSDSGTGIVHNAPAFGEEDNAACLKNGVISEDSVLPNAIDDLGRFTKDVPDFEGVYVKDADKLIIKYLTNTGNLLLASQIRHSYPFCWRSDTPLLYRSVPAWFVRVKNIVPQMLDSVMKSHWVPNTIKEKRFANWIANARDWNVSRNRYWGTPIPLWVSDDFEEVVCVGSIKELEELTGVRNITDLHRDVIDKLTIPSKQGKGDLKRIEEVFDCWFESGSMPYASQHYPFE-NTEKFDERVPANFISEGLDQTRGWFYTLAVLGTHLFGSVPYKNVIVSGIVLAADGRKMSKSLKNYPDPSIVLNKYGADALRLYLINSPVLKAESLKFKEEGVKEVVSKVLLPWWNSFKFL-DGQIALLKKMSN----IDFQYDDSVKSDNVMDRWILASMQSLVQFIHEEMGQYKLYTVVPKLLNFIDELTNWYIRFNRRRLKGE--NGVEDCLKALNSLFDALFTFVRAMAPFTPFLSESIYLRLKEYI--PEAVLAKYGKDGR----SVHFLSYPVVKKEYFDEAIETAVSRMQSVIDLGRNIREKKTISLKTPLKTLVILHSDESYLKDVEALKNYIIEELNVRDVVITSDEAKYGVEYKAVADWPVLGKKLKKDAKKVKDALPSVTSEQVREYLESGKLEVAGIELVKGDLNAIRGL--PESAVQAGQETRTDQD-VLIIMDTNIYSELKSEGLARELVNRIQKLRKKCGLEATDDVLV----EYELVKDTIDFEAIVKEHFDMLSKTC-RSDIAKYDGSKTDPIGD 1055          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVE---IVDRVASCN 886
            MSE  N   SF  EE+ +L  W+EI AF T LE +K K ++SF+DGPPFATG PHYGH+LA ++KDIV R+A  T HHVERRFGWD HGVPIE+ IDKKL I G  DV K G+  YNNECRSIVM Y+ DW   + RLGRWIDF  DYKTMYP FMES W+ FKQ+ EKG VYRG KVMP+ST  +TPLSNFEA+QNYKDVNDP+V + F +     T+L+AWTTTPWTLPSNL+LCVN D +YVK+ +    + FI++ES I  ++K  + E   IV+++   +
Sbjct:    1 MSES-NAHFSFPKEEEKVLSLWDEIDAFHTSLELTKDKPEFSFFDGPPFATGTPHYGHILASTIKDIVPRYATMTGHHVERRFGWDTHGVPIEHIIDKKLGITGKDDVFKYGLENYNNECRSIVMTYASDWRKTIGRLGRWIDFDNDYKTMYPSFMESTWWAFKQLHEKGQVYRGFKVMPYSTGLTTPLSNFEAQQNYKDVNDPAVTIGFNVIGQEKTQLVAWTTTPWTLPSNLSLCVNADFEYVKIYDETRDRYFILLESLIKTLYKKPKNEKYKIVEKIKGSD 284          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFT---------------NEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLH---RESIDDII--IPSKMNKGVLR--RVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPA-DFIAEGIDQTRGWFYT--LTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVIN--------KYGADALRLYMIS-----SPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHS-------SLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITE 2385
            ++  ++VT  +GTG+VH AP  G+DDY + + NG+      I  PVD  G++                 ++T    +      K+I+  L +   L+      HSYP+ WRS  P++ +A P WF  + D+ +  L + +   + P     +R ++++K   +W ISR R WG P+  +      + V + S      +  +K + ++    +  +D+   +P K +       R  +  D WF+SGS  ++ +   +    K      P      EG DQ RGWF +  LT +++     AP++ ++  G  L  +G KMSK + N   P  +I           G D LR Y+I+     + +V G +   V   V + +K   +    +F++L  +       +L+P E+ +   +  L+K N   +T     +   +F++ LI        +YHL+          ++L+ +Y  +++  L    +SS         TL  +L     +++P +P + +
Sbjct:  356 LLHGAHVTSGTGTGLVHTAPGHGQDDYLIGIQNGL-----EIYSPVDHQGRYQLNELPQSVRSIVRDEGDLTKGRQVLDAETAKIILCKLSDLNLLYKSHEYTHSYPYDWRSKKPVIIRATPQWFADLHDVKNLALESISRVKFCPK-RGYSRLSSFMKSRNEWCISRQRSWGIPILSFYKKSEPDSVLMNSEILAHAIEKIKQKGINAWFNDKDNDMKEWLPEKYHDVAHEYCRSQDTMDVWFDSGS-SWSVIKDFYEKSLKLSKLPSPLYQVCLEGSDQHRGWFQSSLLTKVASSNVPVAPYEEVITHGFTLDENGLKMSKSVGNTISPEAIIRGDENLGLPALGVDGLR-YLIAQSNFTTDIVAGPT---VMKHVGEALKKVRL----TFRYLLSNLQKSQDFNLLPIEQLRRVDQYTLYKINELLETTREHYQ-KYNFSKVLITL------QYHLN----------NELSAFYFDISKDILYSNQISSLARR-QVQTTLVHILNAYRAILAPILPVMVQ 845          

Query:  152 KKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQD----WEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLS--NFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXX--------------XXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYV-FKSNQVEIVDRVASCNTKNTFRYSNIL--SK*NKKLVH 946
            +K +  +DGPP+A G  H GH L   +KDI+ R+      ++  + GWDCHG+PIE +  K L+ Q    +  + I       RS+ +K++Q       +         D++  Y TM   +  +   IFK+++E+GL+ R  K + + T   T L+    E  +N+K +   +  V FPL   S  +L                      TL SN A+C N D  Y  ++     +L ++    I  +   +N  E + +    +  N   Y N+L   K  + L+H
Sbjct:   84 EKLFILHDGPPYANGELHLGHALNKILKDIINRYQLSQGKYIFYKPGWDCHGLPIEIKALKDLSAQQIESISPLKI-------RSMALKHAQKAIKRQRETFQHFAILTDWETPYLTMDKDYEINQLNIFKEMYERGLIKRQNKPVYWGTETRTALAEGELEYNENHKSI---AAYVKFPLEKKSQMDLCKKLGITNNLPIYCLIWTSTPWTLLSNRAICFNQDFSYSLLR--LNSELILVETGSIDKLGLTTNSFETIKQFQGTHL-NGLYYQNLLVDDKVGRPLLH 358          

Query:  985 GTGVVHQAPYFGEDDYRVCLSNG-----IIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSD---TPLLNKAVPSWFIRVEDIV-DQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSG---VKVRDLHRESIDDIII-PSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISS----------------------PVVRGQSLKFV----ESGVRDMIKDFF-IPWFNSF-KFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNN--MMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQR 2412
            GTG V   P   ++DY     +      I+   G +    +ECG        ++G+    A K +I+ LKEK         + + P C RS     PLL    P W++   ++  D +         +     E  + +WL + +DW ISR  +WG   P++  +   E        E +R+ G   V  R +           P+  +K  L +  +V D WF SG  P++ + +P  T  K     +P   +  G D    W   + ++   + G  PFK + C  +V  + G+KMSK L N  DPL+VI     D L   ++                        P     +++F      +G RD+  D   +  +  F   ++ ++     +  +  +P    P T   + N  ++++WI+       K     + +    T    + ++   + + Y+  N K L  E   S  +  SA  TL+ +L  A  +I PF+PFI+E  +QRL +R
Sbjct:  431 GTGAVKITPAHDQNDYNTGKRHNLEFINILTDDGLLN---EECG------PEWQGMKRFDARKKVIEQLKEKNLYVGQEDNEMTIPTCSRSGDIIEPLLK---PQWWVSQSEMAKDAIKVVRDGQITITPKSSEAEYFHWLGNIQDWCISRQLWWGHRCPVYFINIEGE--------EHDRIDGDYWVAGRSMEEAEKKAAAKYPN--SKFTLEQDEDVLDTWFSSGLWPFSTLGWPEKT--KDMETFYPFSMLETGWDILFFWVTRMILLGLKLTGSVPFKEVFCHSLVRDAQGRKMSKSLGNVIDPLDVITGIKLDDLHAKLLQGNLDPREVEKAKIGQKESYPNGIPQCGTDAMRFALCAYTTGGRDINLDILRVEGYRKFCNKIYQATKFALMRLGDDYQP----PATEGLSGNESLVEKWILHKLTETSKIVNEALDKRDFLTSTSSIYEFWYLICDVYIE-NSKYLIQE--GSAIEKKSAKDTLYILLDNALKLIHPFMPFISEEMWQRLPKR 918          

Query:  179 PPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVI 661
            PP  TG  H GH L  +++D + R+       V    G+D  G+  +  ++K++  +        G  A+  +      +Y    ++ + +LG   D+ ++  T+ P   +SV   F ++ ++G++YR  +++ +S   +T +SN E +   KDV   +++
Sbjct:  189 PPNVTGALHIGHALTIAIQDSLIRYNRMKGKTVLFLPGFDHAGIATQSVVEKQIWAKDRKTRHDYGREAFVGKVWEWKEEYHSRIKNQIQKLGASYDWSREAFTLSPELTKSVEEAFVRLHDEGVIYRASRLVNWSVKLNTAISNLEVEN--KDVKSRTLL 347          

Query:  182 PFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIE-YEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYR 562
            P+ +G  H GHL    + D + RF  Q  ++V    GWD  G+P E   I++ +N   P    +  I     + +S++  +  DW+             ++  T  P + +   +IF ++FE GL YR
Sbjct:   56 PYPSGALHIGHLRVYVISDSLNRFYKQKGYNVIHPMGWDAFGLPAENAAIERSIN---PAIWTRDNIAKMKQQMQSMLANF--DWD-------------REITTCDPEYYKFTQWIFLKLFENGLAYR 165          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSE---SESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECSILSDTSGTSSEVKDSILSMWFTHDH 3321
            G  L+ K Y P+F YF ++K  +GAFRI+ DSYVTE SGTGVVH AP FGEDDYRV ++NG+I K G++ CPVD  GKFT EVT F G YVK ADK II+ LK+ +RL +  T KH+YPFCWRSDTPL+ KAVP WFIRVE IVD+LL  N + YWVP+FVKE RF NWL++A DW +SRNRYWGTP+PLWVSDDY+EVVCVGS+ EL  LSGV++ DLHRE++D + IPSK  +GVLRRVPEVFDCWFESGSMPYAQVH+PF    + F + FPADFIAEGIDQTRGWFYTL VIST +F K PFKNL+ +G+VLA+DG KMSKR KNYPDP+E+INK+G+DALRLY+I+SPVVR ++LKF E GV+D++KD F+PW+N+++FL   S+  F++  N      +  N   + +N+MD+WI+SFTQSL++F   +M  Y L TV PRL+K+I+ LTNWYVR NRKRL+G+     ED + AI TLF V+   T +++PF PF+TE  YQ +K  + F E         ++K  +S+HY+M+P+  ++LI  +IE +V+ MQ  +ELGR +RD+ T+  K PL EVVI+ QD   ++ + S+++Y+ EELNV+K+T+S+DK K+ + LRAE + + LG +LK  ++ V +A K LT E+L+ ++   ++T+ GH L   DL+ +A   + N      YE  S  + IL+L+D     ++L E +ARE +NRIQ+ RK+  L P D V+I    E   S+ +  +  +H E I  ++ QP+      S+P P      L++     +++K   L +W    H
Sbjct:  269 GASLEGKTYKPMFPYFEQLKS-SGAFRILTDSYVTEESGTGVVHSAPAFGEDDYRVSMANGVIHKGGSLPCPVDANGKFTAEVTDFAGQYVKDADKHIIKWLKQHRRLVHQSTIKHNYPFCWRSDTPLIYKAVPGWFIRVESIVDKLLANNQKCYWVPEFVKEKRFHNWLQNAHDWNVSRNRYWGTPIPLWVSDDYQEVVCVGSVDELAELSGVRLTDLHRENVDHVTIPSKTGRGVLRRVPEVFDCWFESGSMPYAQVHYPFERK-EDFEKTFPADFIAEGIDQTRGWFYTLLVISTALFDKPPFKNLIVNGLVLAADGAKMSKRKKNYPDPMEIINKHGSDALRLYLINSPVVRAETLKFQEKGVKDVVKDVFLPWYNAYRFL-SQSIDQFQRVHNVN--FAYDENNTMELHNIMDKWILSFTQSLVQFVHQEMDAYRLYTVVPRLVKFIEYLTNWYVRFNRKRLKGD--QGQEDAMQAIQTLFGVVLTITKLMAPFTPFLTEHIYQNMKPFIVFDE---------SEKENDSIHYLMVPKTRENLIHTEIERAVSRMQATIELGRVVRDRMTIPTKYPLPEVVIIHQDKQCLEDVISLQNYIKEELNVRKVTVSSDKDKFGLRLRAEPDSQTLGRRLKGAFKQVFQAVKELTDEELKTYEEKGELTVCGHVLSGTDLK-LAYSFDQNGDLPLTYEPHSDSE-ILILLDVTPDQKMLDEGLAREFVNRIQKLRKKAGLQPVDDVSIVYEVEPSGSQRLGEIINAHKEYIQTSVKQPV-----RSSPLP-----ALTEIIHEQTDIKGEKLRLWIFRGH 1060          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS 847
            M+   +E  +F  EE+ IL+ W ++ AF++ L QS+ + +Y+FYDGPPFATG+PHYGH+LAG++KDIVTR+AHQT +HVERRFGWDCHG+P+ Y            DV KMGI  YN+ECR IVM+YS DWE IVSRLGRWIDF+ DYKT+YPWFME+VW++FKQ+ EK +VYRG KVMP+ST C+TPLSNFE+ QNYK+V DP+V V+FPL +     ++AWTTTPWTLPSNLAL VN D++YVKVK+  T K++I+M +R+  +FK+
Sbjct:    1 MASAVSEQHNFPKEEEKILELWKKLDAFKSSLRQSEGRPRYTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQTGYHVERRFGWDCHGLPVVY------------DVAKMGIAKYNDECRKIVMRYSTDWERIVSRLGRWIDFENDYKTLYPWFMETVWWVFKQLHEKNMVYRGFKVMPYSTVCNTPLSNFESNQNYKEVQDPAVFVSFPLDESPDVSMIAWTTTPWTLPSNLALVVNKDMEYVKVKDNSTEKVYIMMAARLDALFKT 257          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQ 349
            M+   +E  +F  EE+ IL+ W ++ AF++ L QS+ + +Y+FYDGPPFATG+PHYGH+LAG++KDIVTR+AHQT +HVERRFGWDCHG+P+EYEID+KLNI+
Sbjct:    1 MASAVSEQHNFPKEEEKILELWKKLDAFKSSLRQSEGRPRYTFYDGPPFATGLPHYGHILAGTIKDIVTRYAHQTGYHVERRFGWDCHGLPVEYEIDQKLNIK 103          

Query: 1903 LRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPF 2367
            +RLY+I+SPVVR ++LKF E GV+D++KD F+PW+N+++FL   S+  F++  N      +  N   + +N+MD+WI+SFTQSL++F   +M  Y L TV PRL+K+I+ LTNWYVR NRKRL+G+     ED + AI TLF V+   T ++  +
Sbjct:   55 IRLYLINSPVVRAETLKFQEKGVKDVVKDVFLPWYNAYRFL-SQSIDQFQRVHNVN--FAYDENNTMELHNIMDKWILSFTQSLVQFVHQEMDAYRLYTVVPRLVKFIEYLTNWYVRFNRKRLKGD--QGQEDAMQAIQTLFGVVLTITKLMLAY 204          

Query: 1348 FVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRL-YMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYI-DQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTL 2598
            +V ++RF   +  + DW ISR   WG  +P W   D E  + VG   E E L   K +     +           K  LR+  +V D WF S   P     +  + D ++    +P   +    +    W   + +      G+ PF  +  +GIV    G+KMSK+L N PD L +I ++GADA+R   MISSP   G  L + ES + +  ++F    +N+ K +          K   GR      +          +W+        +     M ++ L      +   I D   +WY+   +      +  S E +   + T F  L Q   ++ P++PF+TE  Y  + +R D    DDL +    ++ P           N++L+K       AL+Q ++   R  R++  L
Sbjct:  309 YVGQDRF---VVRSPDWCISRQLSWGQRIPAWY--DSENTIYVGKTEE-EALEQYKKQKPELAA----------QKPELRQDEDVLDTWFSSWLWPMQVFGWNENPDNEELKYYYPTKTLVTAPEIIFFWVARMAMAGYEYLGQKPFDKVYFTGIVRDKQGRKMSKQLGNSPDLLALIEEHGADAVRFSVMISSPA--GNDLLYDESSL-EQGRNFSNKMWNALKLI----------KSWEGRT---TKDVAIGEQQFAVDWMEQRVAKASQQIEELMKDFRLSEGLKTIYSLIWDDFCSWYLEWVKPAQEASM--SQELYERTVAT-FEQLLQ---LLHPYMPFVTEEMYHLMNERKDG---DDLIL----KQLPS------FSTVNENLLKEG-----ALLQQLITSVRDARNKNQL 671          

Query:   74 ADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWED--------IVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESR 826
            A EEK   K+WN+   F +  ++   +  Y+    PP  TG+ H GH L  +++DI+ R A    ++     G D   +  E ++   L  +G            N   R   ++Y+ +W++         + +LG  +D+ + + TM   +  +V  +F  ++ KG +YRGVK++ +     T LS+ E    +K  N     V + L  D    +   T  P T+  + A+CV+P+ +  +   +K  K F+ + +R
Sbjct:   11 AAEEKW-YKHWNDSGYFTSVPDE---RPSYTVVIPPPNVTGVLHMGHALNDTVQDILVRRAKMQGYNTCWVPGTDHASIATEAKVVNMLKERG---------IDKNALSREEFLEYAWEWKEKYGGIILQQLKKLGCALDWNRTHFTMDDEYYAAVIRVFVDLYNKGQIYRGVKMINWDPKAKTALSDEEVI--HKQTNSKLYYVRYKLDGDKEEYITIATVRPETILGDTAICVHPNDE--RYAHLKGRKCFVPLVNR 252          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTAN-AETYWVPDFVK--ENRFTNWLKDARDWAISRNRYWGTPLPL-WVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGID 1722
            I+ D YV    GTG +   P   E+D  +   + +      ++   +E     +   H+EG       K I + L+EK  L       +      R+   +  +    WF+++E++V   + A   E   V  F K  EN + +W+++ RDW ISR  +WG  +P  +  D  E+ V   +I +  +L+  K  +            S ++   L++ P+  D WF S   P +      + + ++    +P + +  G D
Sbjct:   91 IIEDEYVDVEFGTGCLKVTPAHDENDKVLGDKHNL-----EVIDIFNEDASLNSFGLHYEGKDRFVVRKEISKELEEKGFLVKTEVHTNKVGTSERTKAVIEPRLSDQWFLKMEELVKPAIEAVLGEDREVKLFPKKFENTYRHWMENIRDWNISRQLWWGQQIPAYYYGDGKEDFVVAETIEDAVKLAQEKTGN------------SSLSASDLKQDPDALDTWFSSWLWPMSVFDGIRNPENEEIKYYYPTNDLVTGPD 334          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTI--YCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECSILSDTS 3264
            G+ L+ K+Y PLF+YF K   E GAF+++ D+YV E  GTGVVHQAPYFG DDYRVC    II++    +CPVD  G FT+EVT F G YVK ADK II+ LKE  RL N  T KHSYPFCWRSDTPL+ KAVPSWF+RVE +V++LL  N + YWVP+FV+E RF NWL+DARDWAISRNRYWGTP+PLWVSDD++EVVCVGSIAELE L+GVKV DLHRESID + IPS+  KGVLRRV EVFDCWFESGSMPYAQVH+PF    K+F E FPADFIAEGIDQTRGWFYTL V+ST +FGK PFKN++ +G+VLASDGQKMSKR KNYPDP  ++  YGADALRLY+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL   ++   +K+   G   L+  NT  +++N+MD+WI SFTQSLI+FF+ +M  Y L TV PRL+K++D LTNWYVR NR+RL+GE  S  ED + A+ TLF VL+    +++PF PFITE  YQ L   +D + ++        +K   S+HY+M+P+  + LI   IE +V+ MQ+++ELGR IRD+KTL +K PL EVV++ QD +++K I+S++ Y+LEELNV++LTLS DK KY + LRAE +H +LG +LK  ++AV  + K LT+EQLE FQ T +I +  HEL  EDL ++ T +  + +T  QYE+ S    +LVL+D      ++ E VARE+INRIQ+ RK+ +L+P D +T+  +C  E E + +V ++H + I  T   P++       P P     I+++T+
Sbjct:  281 GKNLKGKKYKPLFQYFSKCG-EKGAFQVVLDNYVKEEEGTGVVHQAPYFGADDYRVCAEYNIIQRDQPPICPVDASGCFTSEVTDFAGQYVKDADKNIIKWLKENGRLVNFSTFKHSYPFCWRSDTPLIYKAVPSWFVRVEHMVEKLLDCNGKCYWVPEFVREKRFGNWLRDARDWAISRNRYWGTPIPLWVSDDFQEVVCVGSIAELEELTGVKVADLHRESIDSLTIPSRCGKGVLRRVTEVFDCWFESGSMPYAQVHYPFENK-KEFEESFPADFIAEGIDQTRGWFYTLLVLSTALFGKPPFKNVIVNGLVLASDGQKMSKRKKNYPDPALIVQNYGADALRLYLINSPVVRAENLRFKEEGVRDILKDVFLPWYNAYRFLVQ-NVQRLQKEDGIG--FLYNENTAKQSDNIMDKWIQSFTQSLIQFFKAEMDAYRLYTVVPRLVKFVDMLTNWYVRTNRRRLKGE--SGTEDCLWALETLFSVLFSMCRLMAPFTPFITEMMYQNLCHLIDPASVE--------EKDASSIHYLMLPQVRESLIDKRIECAVSQMQSVIELGRVIRDRKTLPVKYPLKEVVVIHQDPEALKDIQSLQQYILEELNVRQLTLSTDKDKYGIRLRAEPDHMVLGKRLKGAFKAVTASIKELTSEQLEAFQKTGRIMVNEHELHEEDLRLMYTFDQSSGST-AQYEAHSDAQ-VLVLLDVTPDQSMVDEGVAREVINRIQKLRKKGHLVPSDEITVHYHCQPEGEYLASVIQAHTDFILGTTKAPLL-----PYPVPKSASIIIAETT 1058          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKS-NQVEIVDRVASCNTKN 895
            M E   E+I+F  EE+ IL++W +   F+ CL+QSK++ +Y+FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  +VERRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CR+IVM+YS +WE  V R+GRWIDFK DYKT+YPWFME+VW++FKQ+++KG+VYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSVIV FPL +D    L+AWTTTPWTLPSNLALCVNPD  YVKVK+  T K +I+ME+R+G +FKS ++  ++D+    N K 
Sbjct:    1 MVEPVPESINFPSEEEKILEFWQKKDCFQECLKQSKNRPRYTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFYVERRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRNIVMRYSHEWETSVKRMGRWIDFKNDYKTLYPWFMETVWWVFKQLYDKGMVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVIVNFPLVEDKDVSLIAWTTTPWTLPSNLALCVNPDYLYVKVKDNSTDKTYIMMEARLGALFKSESEYTVLDKFPGKNLKG 286          

Query:  811 YNGIKNRICFQIKSSGNC**GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGW--------------------FYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTI--YCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECSILSDTS 3264
            Y  +K   CF +   G    G+ L+ K+Y PLF+YF K   E GAF+++ D+YV E  GTGVVHQAPYFG DDYRVC    II++    +CPVD  G FT+EVT F G YVK ADK II+ LKE  RL N  T KHSYPFCWRSDTPL+ KAVPSWF+RVE +V++LL  N + YWVP+FV+E RF NWL+DARDWAISRNRYWGTP+PLWVSDD++EVVCVGSIAELE L+GVKV DLHRESID + IPS+  KGVLRRV EVFDCWFESGSMPYAQVH+PF    K+F E FPADFIAEGIDQTRG                     FYTL V+ST +FGK PFKN++ +G+VLASDGQKMSKR KNYPDP  ++  YGADALRLY+I+SPVVR ++L+F E GVRD++KD F+PW+N+++FL  +       ++  G   L+  NT  +++N+MD+WI SFTQSLI+FF+ +M  Y L TV PRL+K++D LTNWYVR NR+RL+GE  S  ED + A+ TLF VL+    +++PF PFITE  YQ L   +D + ++        +K   S+HY+M+P+  + LI   IE +V+ MQ+++ELGR IRD+KTL +K PL EVV++ QD +++K I+S++ Y+LEELNV++LTLS DK KY + LRAE +H +LG +LK  ++AV  + K LT+EQLE FQ T +I +  HEL  EDL ++ T +  + +T  QYE+ S    +LVL+D      ++ E VARE+INRIQ+ RK+ +L+P D +T+  +C  E E + +V ++H + I  T   P++       P P     I+++T+
Sbjct:  244 YVKVKGEECFSLGCHGILFPGKNLKGKKYKPLFQYFSKCG-EKGAFQVVLDNYVKEEEGTGVVHQAPYFGADDYRVCAEYNIIQRDQPPICPVDASGCFTSEVTDFAGQYVKDADKNIIKWLKENGRLVNFSTFKHSYPFCWRSDTPLIYKAVPSWFVRVEHMVEKLLDCNGKCYWVPEFVREKRFGNWLRDARDWAISRNRYWGTPIPLWVSDDFQEVVCVGSIAELEELTGVKVADLHRESIDSLTIPSRCGKGVLRRVTEVFDCWFESGSMPYAQVHYPFENK-KEFEESFPADFIAEGIDQTRGCSLVDTNSYFLSFFIFVCHCRFYTLLVLSTALFGKPPFKNVIVNGLVLASDGQKMSKRKKNYPDPALIVQNYGADALRLYLINSPVVRAENLRFKEEGVRDILKDVFLPWYNAYRFLVQNVQ---RLQKEDGIGFLYNENTAKQSDNIMDKWIQSFTQSLIQFFKAEMDAYRLYTVVPRLVKFVDMLTNWYVRTNRRRLKGE--SGTEDCLWALETLFSVLFSMCRLMAPFTPFITEMMYQNLCHLIDPASVE--------EKDASSIHYLMLPQVRESLIDKRIECAVSQMQSVIELGRVIRDRKTLPVKYPLKEVVVIHQDPEALKDIQSLQQYILEELNVRQLTLSTDKDKYGIRLRAEPDHMVLGKRLKGAFKAVTASIKELTSEQLEAFQKTGRIMVNEHELHEEDLRLMYTFDQSSGST-AQYEAHSDAQ-VLVLLDVTPDQSMVDEGVAREVINRIQKLRKKGHLVPSDEITVHYHCQPEGEYLASVIQAHTDFILGTTKAPLL-----PYPVPKSASIIIAETT 1061          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVK 784
            M E   E+I+F  EE+ IL++W +   F+ CL+QSK++ +Y+FYDGPPFATG+PHYGH+LAG++KDIVTRFAHQ+  +VERRFGWDCHG+P+EYEIDK L I+GP DV KMGI  YN +CR+IVM+YS +WE  V R+GRWIDFK DYKT+YPWFME+VW++FKQ+++KG+VYRGVKVMPFSTAC+TPLSNFE+ QNYKDV DPSVIV FPL +D    L+AWTTTPWTLPSNLALCVNPD  YVKVK
Sbjct:    1 MVEPVPESINFPSEEEKILEFWQKKDCFQECLKQSKNRPRYTFYDGPPFATGLPHYGHILAGTIKDIVTRFAHQSGFYVERRFGWDCHGLPVEYEIDKTLGIKGPEDVAKMGIAEYNKQCRNIVMRYSHEWETSVKRMGRWIDFKNDYKTLYPWFMETVWWVFKQLYDKGMVYRGVKVMPFSTACNTPLSNFESHQNYKDVQDPSVIVNFPLVEDKDVSLIAWTTTPWTLPSNLALCVNPDYLYVKVK 248          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVT-HFEGIYVKT-ADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARD-WAISRNRYWGTPLPLWVSDDYEEVV----CVGSIAELERLSGVKVR-DLHRESIDDIIIPSKMNKGVLR---RVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVIN--------KYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQ-----LTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQ 2397
            ++  ++VT + GTG+VH AP  G +DY V     +      + C VD+ G+FT       +G+ V T   + +I  L+E   L       HSYP+ WR+  P+L +    WFI    + D+      +   +P+  + +     + D R  W ISR R WG P+P++   D  E +     V  IAEL +  G     +L  E++    +  K   G      R  +V D WF+SGS         ++   ++ +    AD   EG DQ  GWF +  + S  +  KAP+K LV  G  ++  G+KMSK L N  DP EVIN         YGAD LR ++  S +    S   + S   +  +D      N+ +FL   +L  F+ +  S            K  + +D++++     L++ F  ++++ + +  A R+I+ +       L+++Y  + + RL  +   S     S    L  +L   T  ++P +P + E  YQ
Sbjct:  367 LLPANHVTMAKGTGLVHTAPAHGMEDYSVASQFKL-----PVDCMVDDDGRFTELAGPQLQGLSVLTEGTEKVISMLRENGALVLEQQCVHSYPYDWRTKQPVLIRPSKQWFINTLSLRDKAKEVLQKVQVLPESARGSLLA--MLDRRTYWCISRQRSWGVPIPVFYHKDSGEPLINKDTVTHIAELFKEKGSDCWWELPIETLLPPNVLKKAGAGAASDFVRGEDVLDIWFDSGSS--------WAAVLEELDSR--ADVCVEGKDQLGGWFQSSLLTSVAVRNKAPYKCLVVHGFAVSETGEKMSKSLGNVIDPDEVINGGKDGGAPAYGADVLRWWVAESNIF---SELQIGSNALNSARDSISKLRNTLRFLL-GNLQGFDPRTQS---------VDAKRMHYVDQYML----HLLRQFSMKVTDAYSEFDASRVIRLLQAFVTRDLSSFYFSIIKDRLYCDPEDSPGR-RSCQTALEEILDGVTRSVAPILPHLAEEVYQ 837          

Query:  140 QSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLR------------DDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFII 814
            + K KKK+S +DGPP+A G PH GH L   +KDI  RF       V    GWDCHG+PIE +    L   G T +            R          +    R G   D+++ Y T    +  +   +F++++ KGLVY+  K + +S +  T L+  E + N + V+  +V  TF L             DD S  LL WTT PWTLP+N A+C  P+ +Y  VK   T +L ++
Sbjct:   96 ERKAKKKFSLHDGPPYANGAPHVGHALNKILKDIRNRFEVLRGRQVHYVPGWDCHGLPIELKALGGLCASGLTPLQ------IRQRAREFAEGAIAQQKAAFQRWGVMADWEQCYYTFDGPYEAAQLKVFQEMYSKGLVYQDYKPVFWSPSSRTALAEAELEYNPEHVSR-AVYATFALTTPPPGLPAEEGLDDVS--LLVWTTQPWTLPANQAVCYMPNAEYSVVKRADTSQLLLV 323          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVT-HFEGIYVKT-ADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARD-WAISRNRYWGTPLPLWVSDDYEEVV----CVGSIAELERLSGVKV-RDLHRESIDDIIIPSKMNKGVLR---RVPEVFDCWFESGSMPYAQVH----------------FPFSTDFKQFNEI-FPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVIN--------KYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQ-----LTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQ 2397
            ++  ++VT + GTG+VH AP  G +DY V     +      + C VD+ G+FT       +G+ V T   + +I  L+E   L       HSYP+ WR+  P+L +    WFI    + D+      +   +P+  + +     + D R  W ISR R WG P+P++   D  E +     V  IAEL +  G     +L  E++    +  K   G      R  +V D WF+SGS   A +                  P S       E+   AD   EG DQ  GWF +  + S  +  KAP+K LV  G  ++  G+KMSK L N  DP EVIN         YGAD LR ++  S +    S   + S   +  +D      N+ +FL   +L  F+ +  S            K  + +D++++     L++ F  ++++ + +  A R+I+ +       L+++Y  + + RL  +   S     S    L  +L   T  ++P +P + E  YQ
Sbjct:  367 LLPANHVTMAKGTGLVHTAPAHGMEDYSVASQFKL-----PVDCMVDDDGRFTELAGPQLQGLSVLTEGTEKVISMLRENGALVLEQQCVHSYPYDWRTKQPVLIRPSKQWFINTLSLRDKAKEVLQKVQVLPESARGSLLA--MLDRRTYWCISRQRSWGVPIPVFYHKDSGEPLINKDTVTHIAELFKEKGSDCWWELPIETLLPPNVLKKAGAGAASDFVRGEDVLDIWFDSGSSWAAVLEGEGQEDPEEPERRLRWLPSSRRSPLGAELDSRADVCVEGKDQLGGWFQSSLLTSVAVRNKAPYKCLVVHGFAVSETGEKMSKSLGNVIDPDEVINGGKDGGAPAYGADVLRWWVAESNIF---SELQIGSNALNSARDSISKLRNTLRFLL-GNLQGFDPRTQS---------VDAKRMHYVDQYML----HLLRQFSMKVTDAYSEFDASRVIRLLQAFVTRDLSSFYFSIIKDRLYCDPEDSPGR-RSCQTALEEILDGVTRSVAPILPHLAEEVYQ 864          

Query:  140 QSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLR------------DDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFII 814
            + K KKK+S +DGPP+A G PH GH L   +KDI  RF       V    GWDCHG+PIE +    L   G T +            R          +    R G   D+++ Y T    +  +   +F++++ KGLVY+  K + +S +  T L+  E + N + V+  +V  TF L             DD S  LL WTT PWTLP+N A+C  P+ +Y  VK   T +L ++
Sbjct:   96 ERKAKKKFSLHDGPPYANGAPHVGHALNKILKDIRNRFEVLRGRQVHYVPGWDCHGLPIELKALGGLCASGLTPLQ------IRQRAREFAEGAIAQQKAAFQRWGVMADWEQCYYTFDGPYEAAQLKVFQEMYSKGLVYQDYKPVFWSPSSRTALAEAELEYNPEHVSR-AVYATFALTTPPPGLPAEEGLDDVS--LLVWTTQPWTLPANQAVCYMPNAEYSVVKRADTSQLLLV 323          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSD---TPLLNKAVPSWFIRVEDIVDQLLTANAETYW--VPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAE----LERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISS----------------------PVVRGQSLKFV----ESGVRDMIKD---------FFIPWFNSFKFLFHS---SLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKY-IDQLTNWYVRMNRKRLRG--EIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQR 2412
            I+ D +V  S GTG V   P    +DY V       R +   +  +DE G   N    F G+    A K ++Q LK++             P C RS     PLL    P W++   D+  +   A  E     +PD   +  F NW+ + RDW ISR  +WG  +P +     +  V  G   +    +   S V+ R+   +  +        +K  LR+  +V D WF SG  P++   +P  T+    N  +P   +  G D    W   + ++   + GK PFK +    +V  + G+KMSK L N  DPL+VI     + L   +  S                      P     +L+F      S  RD+  D         F    +N+ KF   +   + VP EK Q SG              ++ D WI+S   + +         Y    +   +  + + +L + Y+   +       E      + +    TL+  L     ++SP +PF+TE  YQRL +R
Sbjct:  589 IVLDDFVDMSFGTGAVKITPAHDHNDYEVGE-----RHSLAFINILDENGLLINVPPPFLGMKRFEARKAVLQALKDRGHFKEIKDNPMVVPVCSRSKDIVEPLLK---PQWYVSCRDMGREAADAVREGRLKIIPDHHLKTWF-NWMDNIRDWCISRQLWWGHRIPAYFVTVSDPSVKAGEDMDGHYWVSGRSEVEAREKAAKRFN-----VSADKITLRQDEDVLDTWFSSGIFPFSIFGWPNETE--DLNVFYPGTLLETGHDILFFWVARMVMMGLKLTGKLPFKEVYLHAVVRDAHGRKMSKSLGNVIDPLDVITGISLEGLHAQLTDSNLDPVEVEKAKQGQKSDYPNGIPECGTDALRFALCAYTSQGRDINLDVNRILGYRHFCNKLWNAVKFAMKTLGDTFVPLEKAQLSGE------------ESVSDRWILSRLSAAVALCDAGFKAYDFPAITTAVYNFWLYELCDVYLESVKPVFSKAEEDGDRQREAMVCRQTLYTCLEVGLRLLSPLMPFVTEELYQRLPRR 1097          

Query:  179 PPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIV----SRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQ------------NYKDVNDPSVIVTFPLRDDSS 691
            PP  TG  H GH L  +++D +TR+            G D  G+  +  ++KKL  +       +G   +  E    V K+  +  D +     +LG  +D+ +   TM P    +V   F ++ E G++YR  +++ +S   ++ +S+ E  +             YKD  +  V+V+F  + + S
Sbjct:  359 PPNVTGSLHLGHALTNAIQDCLTRWHRMRGETTLWNPGCDHAGIATQVVVEKKLMRERGLSRHDLGRENFIQE----VWKWKNEKGDRIYHQLKKLGSSLDWDRACFTMDPKLSYAVQEAFIRMHEDGVIYRSKRLVNWSCTLNSAISDIEVDKKELSGRTLLPVPGYKDKVEFGVLVSFAYKVEGS 541          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECSILSDTSGTSSEVKDSILSMWFTHDHNRLKTDNRKCLPKSSNVEVICDGDLNSVVQLDVMGIDSWDELLRHVRVAFEWRRFAVAPVTLLDVNDKPIAPVAPSTLKGQRVFVRSF 3585
            GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTD KQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECN+DLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECSILSDTSGTSSEVKDSILSMWFTHDH+RLKTDNRKCLPKSSNVEVICDGDLNSVVQLDVMGIDSWDELLRHVRVAFEWRRFAVAPVTLLDVNDKPIAPVAPSTLKGQRVFVRSF
Sbjct:  275 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDLKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNQDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECSILSDTSGTSSEVKDSILSMWFTHDHDRLKTDNRKCLPKSSNVEVICDGDLNSVVQLDVMGIDSWDELLRHVRVAFEWRRFAVAPVTLLDVNDKPIAPVAPSTLKGQRVFVRSF 1179          

Query:   41 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEI 862
            MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSTELLAWTTTPWTLPSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEI
Sbjct:    1 MSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSTELLAWTTTPWTLPSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEI 274          

Query:  871 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNKDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECSILSDTSGTSSEVKDSILSMWFTHDHNRLKTDNRKCLPKSSNVEVICDGDLNSVVQLDVMGIDSWDELLRHVRVAFEWRRFAVAPVTLLDVNDKPIAPVAPSTLKGQRVFVRSF 3585
            GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTD KQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECN+DLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECSILSDTSGTSSEVKDSILSMWFTHDH+RLKTDNRKCLPKSSNVEVICDGDLNSVVQLDVMGIDSWDELLRHVRVAFEWRRFAVAPVTLLDVNDKPIAPVAPSTLKGQRVFVRSF
Sbjct:  284 GRELQYKEYIPLFEYFIKMKQETGAFRIMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGVLRRVPEVFDCWFESGSMPYAQVHFPFSTDLKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQRLDFSEIDDLKVGIDNQKCPESVHYIMIPECNQDLIKPDIEESVALMQTIVELGRKIRDQKTLALKSPLMEVVIVSQDLDSIKRIESVESYVLEELNVKKLTLSNDKKKYNVELRAELNHRLLGVKLKKDYQAVIKASKTLTTEQLEEFQATSKITILGHELGSEDLEVIATVNNDNKTTDCQYESRSTPDGILVLMDCHQSDELLKEAVAREIINRIQRRRKELNLIPEDPVTIYCWSESESVRAVFESHAEMIYRTILQPIIVRNTNSNPNPICECSILSDTSGTSSEVKDSILSMWFTHDHDRLKTDNRKCLPKSSNVEVICDGDLNSVVQLDVMGIDSWDELLRHVRVAFEWRRFAVAPVTLLDVNDKPIAPVAPSTLKGQRVFVRSF 1188          

Query:   17 NYFKIKLDMSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEI 862
            NYF    DMSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSTELLAWTTTPWTLPSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEI
Sbjct:    4 NYFL--RDMSEFFNEAISFADEEKLILKYWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVNDPSVIVTFPLRDDSSTELLAWTTTPWTLPSNLALCVNPDLDYVKVKEVKTGKLFIIMESRIGYVFKSNQVEI 283          

Query:  967 YVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCP----VDECGKFTNEVTHFEGIYVKTADKLI------IQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNK------GVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFH--SSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQ 2409
            +VT++ GTG+VH AP  G DD+ +  SN  +      V       D CGK   ++     I+    DK+I      I H+++           HSYP+ WR++ P++ +    WFI V  + D  L    +    P  VK      ++++  +W ISR R WG P+P+   ++ + +V    +  + +    +  D         ++P    K        LR+  ++FD WF+SG   Y       S D              EG+DQ RGWF +  ++   + G +P+KNLVC G  +  + +KMSK + N  DP EVI +YG D LR +  +S  ++ QS   + + + D I   +  + N F+FL    S+++     Q S  P LF    P       D +I+   +  I    G    Y  D V   L +   +++N+Y  + + RL  +  SS E + S+  TL F+L+    +  P  P +     Q + Q
Sbjct:  324 FVTDNKGTGLVHIAPAHGIDDFHLMKSN--VDYQSVFVTDDGKYTDICGKDLCKL----DIFKSGLDKIISLLRSNILHIEDLI---------HSYPYDWRTNKPVIIRLSTQWFIDVGKLSDHALREYQKINVYPPTVK-GFMLQFIRNRPNWCISRQRKWGVPIPVLYDENNKVIVDKEFLNYVSKKMENEGSDFWWHDNVSKLVPENFLKKWDLLGSQLRKSEDIFDIWFDSGLSWYCSKVSDKSIDV-----------YLEGMDQFRGWFSSSLLMGVALEGSSPYKNLVCHGFTVDGESRKMSKSVGNVIDPAEVIQRYGIDVLRYWACTSG-LKPQSC--ISTSILDNIDKKYFSFRNMFRFLAGNCSNILDISLSQFSD-PHLFTSLLP------QDRYILHVVRRSISKIEGHFENYQYDMVTSLLEELESKISNFYFTIIKDRLYCDNPSS-ETYKSSNTTLGFILHSLIPVCLPIFPCLILEIVQSINQ 784          

Query:  140 QSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVN-DPSVIVTFPL-------RDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFI 811
             S+  K +  +DGPP+A G PH GH L   +KDI+ ++      +V+ + GWDCHG+PIE +     N   P D+          +   I  KY    +      G   D+   Y T    +       F +++ K L++R  + +P   +CS+  +  E++  Y + +   ++ V F L        D  +  LL WTTTPWTL +N A+C+N D+ Y+  +   + K+ I
Sbjct:   55 SSECNKHFVIHDGPPYANGSPHVGHALNKILKDIIVQYKKLQGFNVDFKPGWDCHGLPIEMK-SSHFNFTSPMDIRL--------KSSEIAKKYIDIQKTAFKSWGVSADWNNSYATFDYHYQSKEIQAFNKLYHKNLIFR--ESLPTFWSCSSKTALAESELEYNENHLSKTLFVKFQLLPTKYLFEDFCNISLLIWTTTPWTLIANEAVCINRDMKYLICERNNSDKIVI 275          

Query:  967 YVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCP----VDECGKFTNEVTHFEGIYVKTADKLI------IQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLLTANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNK------GVLRRVPEVFDCWFESGSMPYAQVHFPFSTDFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVINKYGADALRLYMISSPVVRGQSLKFVESGVRDMIKDFFIPWFNSFKFLFH--SSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKYIDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRLKQ 2409
            +VT++ GTG+VH AP  G DD+ +  SN  +      V       D CGK   ++     I+    DK+I      I H+++           HSYP+ WR++ P++ +    WFI V  + D  L    +    P  VK      ++++  +W ISR R WG P+P+   ++ + +V    +  + +    +  D         ++P    K        LR+  ++FD WF+SG   Y       S D              EG+DQ RGWF +  ++   + G +P+KNLVC G  +  + +KMSK + N  DP EVI +YG D LR +  +S  ++ QS   + + + D I   +  + N F+FL    S+++     Q S  P LF    P       D +I+   +  I    G    Y  D V   L +   +++N+Y  + + RL  +  SS E + S+  TL F+L+    +  P  P +     Q + Q
Sbjct:  324 FVTDNKGTGLVHIAPAHGIDDFHLMKSN--VDYQSVFVTDDGKYTDICGKDLCKL----DIFKSGLDKIISLLRSNILHIEDLI---------HSYPYDWRTNKPVIIRLSTQWFIDVGKLSDHALREYQKINVYPPTVK-GFMLQFIRNRPNWCISRQRKWGVPIPVLYDENNKVIVDKEFLNYVSKKMENEGSDFWWHDNVSKLVPENFLKKWDLLGSQLRKSEDIFDIWFDSGLSWYCSKVSDKSIDV-----------YLEGMDQFRGWFSSSLLMGVALEGSSPYKNLVCHGFTVDGESRKMSKSVGNVIDPAEVIQRYGIDVLRYWACTSG-LKPQSC--ISTSILDNIDKKYFSFRNMFRFLAGNCSNILDISLSQFSD-PHLFTSLLP------QDRYILHVVRRSISKIEGHFENYQYDMVTSLLEELESKISNFYFTIIKDRLYCDNPSS-ETYKSSNTTLGFILHSLIPVCLPIFPCLILEIVQSINQ 784          

Query:  140 QSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIVSRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQNYKDVN-DPSVIVTFPL-------RDDSSXXXXXXXXXXXXXXSNLALCVNPDLDYVKVKEVKTGKLFI 811
             S+  K +  +DGPP+A G PH GH L   +KDI+ ++      +V+ + GWDCHG+PIE +     N   P D+          +   I  KY    +      G   D+   Y T    +       F +++ K L++R  + +P   +CS+  +  E++  Y + +   ++ V F L        D  +  LL WTTTPWTL +N A+C+N D+ Y+  +   + K+ I
Sbjct:   55 SSECNKHFVIHDGPPYANGSPHVGHALNKILKDIIVQYKKLQGFNVDFKPGWDCHGLPIEMK-SSHFNFTSPMDIRL--------KSSEIAKKYIDIQKTAFKSWGVSADWNNSYATFDYHYQSKEIQAFNKLYHKNLIFR--ESLPTFWSCSSKTALAESELEYNENHLSKTLFVKFQLLPTKYLFEDFCNISLLIWTTTPWTLIANEAVCINRDMKYLICERNNSDKIVI 275          

Query:  952 IMCDSYVTESSGTGVVHQAPYFGEDDYRVCLSNGIIRKAGTIVCPVDECGKFTNEVTHFEGIYVKTADKLIIQHLKEKKRLFNHGTEKHSYPFCWRSDTPLLNKAVPSWFIRVEDIVDQLL--TANAETYWVPDFVKENRFTNWLKDARDWAISRNRYWGTPLPLWVSDDYEEVVCVGSIAELERLSGVKVRDLHRESIDDIIIPSKMNKGV----LRRVPEVFDCWFESGSMPYAQVHFPFST-DFKQFNEIFPADFIAEGIDQTRGWFYTLTVISTIIFGKAPFKNLVCSGIVLASDGQKMSKRLKNYPDPLEVIN-------------------------------------KYGADALRLYMIS-SPVVRGQSLKFVE-SGVRDMIKDFFIPWFNSFKFLFHSSLVPFEKKQNSGRPLLFKPNTPPKTNNMMDEWIISFTQSLIKFFRGQMSEYHLDTVAPRLIKY-IDQLTNWYVRMNRKRLRGEIVSSNEDWISAIHTLFFVLYQATVMISPFVPFITEFFYQRL 2403
            I+CDS+V +  GTGVV   P    +DY V   + +       +  + + G        F G+    A   II+ +KE              P C +S   +       W+++ +D+  + L      E   +P+ V    +T W++D  DW ISR  +WG  +P+     Y+  +  G     E  + +  R  H E+I   +   K NK +    + + P+V D WF S   P+A + +P +T D K+F   +P + +  G D    W   + +I   + GK PF  +    ++  + G+KMSK L N  +P +VIN                                     + G DALR  +++ +   R  +L  +  +G R+         + +F+F     +    K   S + +     T  +T    D+WI+S     +      +  Y+L      + ++ + +  + Y+    K  R   +S  +D I  +H L+  +     ++ P +PFITE  +QRL
Sbjct:  341 IICDSFVEKDFGTGVVKITPAHDHNDYEVGKRHNL-----EFINILSDDGHILEGFGEFSGMRRFDARVAIIEKMKELGLFEKISDNPMVIPMCSKSKDIIEPIIKNQWYLKCKDMAKEALRVVEEGELKLLPEGVHNIIWTRWMEDCHDWCISRQLWWGHQIPV-----YKVSIDGGYEFADENENWIAARS-HNEAIQ--LASEKFNKPIDKITVEQDPDVLDTWFSSQLFPFATMGWPSNTEDIKKF---YPGNLLETGHDIIFFWVARMVMIGLKMMGKLPFDTVYLHAMIRDAHGKKMSKSLGNVINPYDVINGISLVDLQQSLETGNLDPKELIRARASQAKDFPSGIPQCGTDALRFALLAYTSQSRDINLDVLRINGYRNFCNKI----WQAFRF---CQMFGLSKSIVSVKSIGEIFGTLSET----DKWILSKLSFAVSEINEALKNYNLSQATTIIHRFWLYEFCDVYIEY-AKPFR--FLSPRKDTI--VHVLYECIEVGLRLLHPMMPFITEELHQRL 839          

Query:  101 YWNEIKAFETCLEQSKHKKKYSFYDGPPFATGMPHYGHLLAGSMKDIVTRFAHQTNHHVERRFGWDCHGVPIEYEIDKKLNIQGPTDVMKMGITAYNNECRSIVMKYSQDWEDIV----SRLGRWIDFKKDYKTMYPWFMESVWYIFKQIFEKGLVYRGVKVMPFSTACSTPLSNFEAKQ 628
            +W     F+    + K  +K+     PP  TG+ H GH L  S++D + R+            G D  G+  +  ++KKL  +       +G   +  E    V K+ ++  D +     +LG   DF +   TM     ++V  +F ++FE  L+YR  +++ +S +  + +S+ E  +
Sbjct:   84 WWENKGYFKPEYNEKKSDEKFVIMIPPPNVTGILHIGHALTCSIEDCIVRWNRMQGKQTLWLPGTDHAGIATQTVVEKKLLRERNLTRHDLGREDFIKE----VWKWKEEKGDCILNQLRQLGSSCDFSRLRFTMEESMSKAVTEVFVKLFEDKLIYRSKRLVNWSCSLRSAISDIEVDK 259