H/ACA ribonucleoprotein complex subunit 3

Overview
NameH/ACA ribonucleoprotein complex subunit 3
Smed IDSMED30027335
Length (bp)513
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of H/ACA ribonucleoprotein complex subunit 3 (SMED30027335) t-SNE clustered cells

Violin plots show distribution of expression levels for H/ACA ribonucleoprotein complex subunit 3 (SMED30027335) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of H/ACA ribonucleoprotein complex subunit 3 (SMED30027335) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for H/ACA ribonucleoprotein complex subunit 3 (SMED30027335) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027335

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30027335 dd_Smed_v4_967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30027335 dd_Smed_v4_967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30027335 dd_Smed_v4_967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30027335 dd_Smed_v4_967_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Human
Match: NOP10 (NOP10 ribonucleoprotein [Source:HGNC Symbol;Acc:HGNC:14378])

HSP 1 Score: 72.0182 bits (175), Expect = 6.814e-17
Identity = 33/59 (55.93%), Postives = 44/59 (74.58%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQ 459
            L+YY ++ G R+YTLK F P  Q T  AHPA++SP+DKYS  RI +K+RFK+L TQ P+
Sbjct:    3 LQYYLNEQGDRVYTLKKFDPMGQQTCSAHPARFSPDDKYSRHRITIKKRFKVLMTQQPR 61
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Celegans
Match: nola-3 (Putative H/ACA ribonucleoprotein complex subunit 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9XVR8])

HSP 1 Score: 70.0922 bits (170), Expect = 1.436e-16
Identity = 30/56 (53.57%), Postives = 45/56 (80.36%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQ 450
            LRY+ D++ +R+YTLK   P+ + T+ AHPA++SPEDK S+ RI++K+RF +LPTQ
Sbjct:    3 LRYFLDENQQRVYTLKRTAPSGEQTLTAHPARFSPEDKNSKYRIIIKKRFGLLPTQ 58
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Fly
Match: CG7637 (gene:FBgn0033548 transcript:FBtr0088252)

HSP 1 Score: 65.855 bits (159), Expect = 8.372e-15
Identity = 29/59 (49.15%), Postives = 44/59 (74.58%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQ 459
            L Y  +++G R+YTLK    + +PT+ AHPA++SPEDKYS +R+ +K+RF +L TQ P+
Sbjct:    3 LMYTINENGDRVYTLKKRTEDGRPTLSAHPARFSPEDKYSRQRLTIKKRFGLLLTQKPE 61
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Zebrafish
Match: nop10 (NOP10 ribonucleoprotein homolog (yeast) [Source:NCBI gene;Acc:445391])

HSP 1 Score: 70.4774 bits (171), Expect = 1.869e-16
Identity = 29/59 (49.15%), Postives = 46/59 (77.97%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQ 459
            L++Y +++G+R+YTLK   P+ QPT  AHPA++SP+DK+S  R+ +K+RF +L TQ P+
Sbjct:    3 LQFYLNENGERVYTLKKVDPSGQPTSSAHPARFSPDDKFSRHRVTIKKRFGLLLTQQPR 61
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Xenopus
Match: nop10 (NOP10 ribonucleoprotein [Source:NCBI gene;Acc:548917])

HSP 1 Score: 70.0922 bits (170), Expect = 4.182e-16
Identity = 28/59 (47.46%), Postives = 45/59 (76.27%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQ 459
            L++Y ++ G+R+YT+K   P+ QPT  AHPA++SP+DK+S  R+ +K+RF +L TQ P+
Sbjct:    3 LQFYLNEQGERVYTMKKVSPDGQPTTSAHPARFSPDDKFSRHRVSLKKRFGLLLTQQPR 61
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Mouse
Match: Nop10 (NOP10 ribonucleoprotein [Source:MGI Symbol;Acc:MGI:1913431])

HSP 1 Score: 72.0182 bits (175), Expect = 4.678e-17
Identity = 33/59 (55.93%), Postives = 44/59 (74.58%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQ 459
            L+YY ++ G R+YTLK F P  Q T  AHPA++SP+DKYS  RI +K+RFK+L TQ P+
Sbjct:    3 LQYYLNEQGDRVYTLKKFDPMGQQTCSAHPARFSPDDKYSRHRITIKKRFKVLMTQQPR 61
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q54J26|NOP10_DICDI (H/ACA ribonucleoprotein complex subunit 3 OS=Dictyostelium discoideum OX=44689 GN=nop10 PE=3 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 5.544e-17
Identity = 34/60 (56.67%), Postives = 45/60 (75.00%), Query Frame = 1 
Query:  277 LNLRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLP 456
            ++L YY DKDG+R+YTLK   PN + T  AHPA++S +DKYS ERI +K+RF +L TQ P
Sbjct:    1 MHLMYYNDKDGQRVYTLKKESPNHEATYSAHPARFSVDDKYSRERIALKKRFGLLLTQQP 60
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q9CQS2|NOP10_MOUSE (H/ACA ribonucleoprotein complex subunit 3 OS=Mus musculus OX=10090 GN=Nop10 PE=3 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.272e-16
Identity = 33/59 (55.93%), Postives = 44/59 (74.58%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQ 459
            L+YY ++ G R+YTLK F P  Q T  AHPA++SP+DKYS  RI +K+RFK+L TQ P+
Sbjct:    3 LQYYLNEQGDRVYTLKKFDPMGQQTCSAHPARFSPDDKYSRHRITIKKRFKVLMTQQPR 61
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q9NPE3|NOP10_HUMAN (H/ACA ribonucleoprotein complex subunit 3 OS=Homo sapiens OX=9606 GN=NOP10 PE=1 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 3.272e-16
Identity = 33/59 (55.93%), Postives = 44/59 (74.58%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQ 459
            L+YY ++ G R+YTLK F P  Q T  AHPA++SP+DKYS  RI +K+RFK+L TQ P+
Sbjct:    3 LQYYLNEQGDRVYTLKKFDPMGQQTCSAHPARFSPDDKYSRHRITIKKRFKVLMTQQPR 61
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q6DRH5|NOP10_DANRE (H/ACA ribonucleoprotein complex subunit 3 OS=Danio rerio OX=7955 GN=nop10 PE=3 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.411e-15
Identity = 29/59 (49.15%), Postives = 46/59 (77.97%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQ 459
            L++Y +++G+R+YTLK   P+ QPT  AHPA++SP+DK+S  R+ +K+RF +L TQ P+
Sbjct:    3 LQFYLNENGERVYTLKKVDPSGQPTSSAHPARFSPDDKFSRHRVTIKKRFGLLLTQQPR 61
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. UniProt/SwissProt
Match: sp|Q9XVR8|NOP10_CAEEL (Putative H/ACA ribonucleoprotein complex subunit 3 OS=Caenorhabditis elegans OX=6239 GN=nola-3 PE=3 SV=2)

HSP 1 Score: 70.0922 bits (170), Expect = 1.826e-15
Identity = 30/56 (53.57%), Postives = 45/56 (80.36%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQ 450
            LRY+ D++ +R+YTLK   P+ + T+ AHPA++SPEDK S+ RI++K+RF +LPTQ
Sbjct:    3 LRYFLDENQQRVYTLKRTAPSGEQTLTAHPARFSPEDKNSKYRIIIKKRFGLLPTQ 58
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. TrEMBL
Match: E0VPW0 (H/ACA ribonucleoprotein complex subunit, putative OS=Pediculus humanus subsp. corporis OX=121224 GN=8233476 PE=4 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 1.538e-19
Identity = 40/61 (65.57%), Postives = 48/61 (78.69%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQYK 465
            LRYY D+ G+R+YT     PN +PT  AHPAK+SPEDKYS+ERIL+K+RF ILPTQLP  K
Sbjct:    3 LRYYLDEKGERVYTFSKVDPNGRPTSSAHPAKFSPEDKYSKERILIKKRFGILPTQLPPIK 63
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. TrEMBL
Match: U6JEU9 (H/ACA ribonucleoprotein complex subunit 3 OS=Echinococcus granulosus OX=6210 GN=EGR_07252 PE=4 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 2.017e-19
Identity = 36/60 (60.00%), Postives = 49/60 (81.67%), Query Frame = 1 
Query:  277 LNLRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLP 456
            ++LRYY D DG+R+YT+K   P+ +PT  AHPA+YSP+DKYSE+R+++K RF ILPTQ P
Sbjct:    1 MHLRYYLDADGRRVYTMKFVDPDGKPTQSAHPARYSPDDKYSEQRVMLKMRFNILPTQQP 60
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. TrEMBL
Match: A0A068Y4H5 (H:ACA ribonucleoprotein complex subunit 3 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000535600 PE=4 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 5.891e-19
Identity = 36/60 (60.00%), Postives = 48/60 (80.00%), Query Frame = 1 
Query:  277 LNLRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLP 456
            ++LRYY D DG R+YT+K   P+ +PT  AHPA+YSP+DKYSE+R+++K RF ILPTQ P
Sbjct:    1 MHLRYYLDADGHRVYTMKFVDPDGKPTQSAHPARYSPDDKYSEQRVMLKMRFNILPTQQP 60
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. TrEMBL
Match: A0A2A9LY07 (Putative structural component of H/ACA snoRNP OS=Besnoitia besnoiti OX=94643 GN=BESB_027830 PE=4 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 1.510e-18
Identity = 36/58 (62.07%), Postives = 46/58 (79.31%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLP 456
            LRYY D+ GKR+YTLK   P+  PT+ AHP ++SP+DKYS ER+ +KRRFK+LPTQ P
Sbjct:    3 LRYYTDEQGKRVYTLKSHAPDGTPTLSAHPPRFSPDDKYSAERVALKRRFKLLPTQQP 60
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. TrEMBL
Match: A0A086Q9N6 (Putative nucleolar protein OS=Toxoplasma gondii VAND OX=933077 GN=TGVAND_278270 PE=4 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 1.510e-18
Identity = 36/58 (62.07%), Postives = 46/58 (79.31%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLP 456
            LRYY D+ GKR+YTLK   P+  PT+ AHP ++SP+DKYS ER+ +KRRFK+LPTQ P
Sbjct:    3 LRYYTDEQGKRVYTLKTHAPDGTPTLSAHPPRFSPDDKYSAERVALKRRFKLLPTQQP 60
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Cavefish
Match: nop10 (NOP10 ribonucleoprotein [Source:NCBI gene;Acc:103030258])

HSP 1 Score: 70.0922 bits (170), Expect = 2.514e-16
Identity = 29/59 (49.15%), Postives = 45/59 (76.27%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQ 459
            L++Y +++G+R+YTLK   P  QPT  AHPA++SP+DK+S  R+ +K+RF +L TQ P+
Sbjct:    3 LQFYLNENGERVYTLKKVDPEGQPTSSAHPARFSPDDKFSRHRVTIKKRFGLLLTQQPR 61
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Yeast
Match: NOP10 (Subunit of box H/ACA snoRNP complex; required for pseudouridylation and processing of pre-18S rRNA [Source:SGD;Acc:S000007455])

HSP 1 Score: 63.929 bits (154), Expect = 6.787e-15
Identity = 28/58 (48.28%), Postives = 41/58 (70.69%), Query Frame = 1 
Query:  277 LNLRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQ 450
            ++L Y    DGKRIYTLK    + + T  AHPA++SP+DKYS +R+ +K+RF ++P Q
Sbjct:    1 MHLMYTLGPDGKRIYTLKKVTESGEITKSAHPARFSPDDKYSRQRVTLKKRFGLVPGQ 58
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Nematostella
Match: EDO41549 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3U4])

HSP 1 Score: 78.9518 bits (193), Expect = 3.146e-20
Identity = 34/58 (58.62%), Postives = 45/58 (77.59%), Query Frame = 1 
Query:  277 LNLRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQ 450
            ++L YY D DGKR+YTLK   P+ +PT  AHPA++SP+DKYS  R+ +K+RF ILPTQ
Sbjct:    1 MHLMYYMDNDGKRVYTLKKQDPSGKPTTSAHPARFSPDDKYSRHRVTLKKRFGILPTQ 58
[Close]
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Medaka
Match: nop10 (NOP10 ribonucleoprotein homolog (yeast) [Source:NCBI gene;Acc:445391])

HSP 1 Score: 75.485 bits (184), Expect = 1.680e-18
Identity = 32/59 (54.24%), Postives = 46/59 (77.97%), Query Frame = 1 
Query:  283 LRYYFDKDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQLPQ 459
            L+YY D++G R+YTLK   P+ +PT  AHPA++SP+DK+S  R+L+K+RF IL TQ P+
Sbjct:    3 LQYYLDQNGDRVYTLKKLNPDGEPTSSAHPARFSPDDKFSRHRVLVKKRFGILLTQQPK 61
The following BLAST results are available for this feature:
BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
NOP106.814e-1755.93NOP10 ribonucleoprotein [Source:HGNC Symbol;Acc:HG... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nola-31.436e-1653.57Putative H/ACA ribonucleoprotein complex subunit 3... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG76378.372e-1549.15gene:FBgn0033548 transcript:FBtr0088252[more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nop101.869e-1649.15NOP10 ribonucleoprotein homolog (yeast) [Source:NC... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nop104.182e-1647.46NOP10 ribonucleoprotein [Source:NCBI gene;Acc:5489... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Nop104.678e-1755.93NOP10 ribonucleoprotein [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q54J26|NOP10_DICDI5.544e-1756.67H/ACA ribonucleoprotein complex subunit 3 OS=Dicty... [more]
sp|Q9CQS2|NOP10_MOUSE3.272e-1655.93H/ACA ribonucleoprotein complex subunit 3 OS=Mus m... [more]
sp|Q9NPE3|NOP10_HUMAN3.272e-1655.93H/ACA ribonucleoprotein complex subunit 3 OS=Homo ... [more]
sp|Q6DRH5|NOP10_DANRE1.411e-1549.15H/ACA ribonucleoprotein complex subunit 3 OS=Danio... [more]
sp|Q9XVR8|NOP10_CAEEL1.826e-1553.57Putative H/ACA ribonucleoprotein complex subunit 3... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
E0VPW01.538e-1965.57H/ACA ribonucleoprotein complex subunit, putative ... [more]
U6JEU92.017e-1960.00H/ACA ribonucleoprotein complex subunit 3 OS=Echin... [more]
A0A068Y4H55.891e-1960.00H:ACA ribonucleoprotein complex subunit 3 OS=Echin... [more]
A0A2A9LY071.510e-1862.07Putative structural component of H/ACA snoRNP OS=B... [more]
A0A086Q9N61.510e-1862.07Putative nucleolar protein OS=Toxoplasma gondii VA... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nop102.514e-1649.15NOP10 ribonucleoprotein [Source:NCBI gene;Acc:1030... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
NOP106.787e-1548.28Subunit of box H/ACA snoRNP complex; required for ... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO415493.146e-2058.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nop101.680e-1854.24NOP10 ribonucleoprotein homolog (yeast) [Source:NC... [more]
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BLAST of H/ACA ribonucleoprotein complex subunit 3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 0
Match NameE-valueIdentityDescription
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027335 ID=SMED30027335|Name=H/ACA ribonucleoprotein complex subunit 3|organism=Schmidtea mediterranea sexual|type=transcript|length=513bp
ATGTGTACCGCGGATAAATTTGTTTATCCGGTCAGTTCACATCTATTGTG
GTCATTATATGAATTCTCGTATGATCATGAACTTTCAAGTAGGATCACTA
GTTATATCGGGGTTGCAGATTGGAATCTTTGGGTCATGAGTACAATATTC
TGGAAGCTCTCTCAGCGTTTATCGGAAAGCAGGTCATCACGTCACCATGG
TCAAAACAAAATCAGTGGTGAGGTTCGGTTTTTTGATACACATTTATTGG
GTGATTTCCAAATGCCACTCGACATGTTAAATTTAAGGTACTATTTTGAT
AAGGATGGAAAGAGAATTTATACGTTAAAGTGTTTTGGTCCTAATCAGCA
ACCTACTATTTGTGCTCATCCTGCAAAGTATTCTCCCGAAGATAAATACT
CTGAAGAAAGAATACTAATGAAAAGAAGATTTAAAATTTTACCAACCCAA
TTGCCACAATATAAATATTAATTTCTACGTATATTTATCATAATATATTC
ATTGATAATTTTA
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protein sequence of SMED30027335-orf-1

>SMED30027335-orf-1 ID=SMED30027335-orf-1|Name=SMED30027335-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=157bp
MCTADKFVYPVSSHLLWSLYEFSYDHELSSRITSYIGVADWNLWVMSTIF
WKLSQRLSESRSSRHHGQNKISGEVRFFDTHLLGDFQMPLDMLNLRYYFD
KDGKRIYTLKCFGPNQQPTICAHPAKYSPEDKYSEERILMKRRFKILPTQ
LPQYKY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR007264H/ACA_rnp_Nop10
Vocabulary: biological process
TermDefinition
GO:0042254ribosome biogenesis
GO:0001522pseudouridine synthesis
Vocabulary: molecular function
TermDefinition
GO:0030515snoRNA binding
Vocabulary: cellular component
TermDefinition
GO:0019013viral nucleocapsid
GO:0030529intracellular ribonucleoprotein complex