Endoplasmin

Overview
NameEndoplasmin
Smed IDSMED30027314
Length (bp)2699
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Endoplasmin (SMED30027314) t-SNE clustered cells

Violin plots show distribution of expression levels for Endoplasmin (SMED30027314) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Endoplasmin (SMED30027314) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Endoplasmin (SMED30027314) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30027314

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymal cellSMED30027314SMESG000068132.1 dd_Smed_v4_11908_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30027314SMESG000068132.1 Contig39506newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30027314SMESG000068132.1 Contig39506uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30027314SMESG000068132.1 Contig27300newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30027314SMESG000068132.1 Contig27300uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
testis primordiumSMED30027314SMESG000068132.1 PL030015A20A11_SE3GPL10652PMID:20844018
Wang et al., 2010
whole organism juvenile cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Endoplasmin vs. Ensembl Human
Match: HSP90B1 (heat shock protein 90 beta family member 1 [Source:HGNC Symbol;Acc:HGNC:12028])

HSP 1 Score: 683.715 bits (1763), Expect = 0.000e+0
Identity = 364/738 (49.32%), Postives = 511/738 (69.24%), Query Frame = 3
Query:  183 TLDSTIEDNEIKLKKTMKEPL------SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSK--TSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            T  S   D+E+ +  T++E L      S+TDDEV++REEEAI+LDGL+ +Q++E+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL++KIK DK  N+L + DTG+GMTR+ELVK LGTIAKSGT+EFL+K+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN FSV  DPRGNTLGRGT I L LK  AS+YLE + ++ LV++YSQ+++FPIY+W+SK  T EE   ++    +   + D+ A V +EE +      K    VWDWE +N  KPIW R   EV E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L++P+ AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  +++   FWKEF   IK+G+IED +NR RL KL++  SS    ++T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD++E +K      + EF PL++++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       + +++        D  +++ A  L ETA + SGYL+ D   Y + +E +L+L+
Sbjct:   15 TFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESD-SNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKD--KALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINP---RHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLS 746          
BLAST of Endoplasmin vs. Ensembl Human
Match: HSP90AB1 (heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258])

HSP 1 Score: 497.278 bits (1279), Expect = 5.525e-164
Identity = 284/697 (40.75%), Postives = 435/697 (62.41%), Query Frame = 3
Query:  348 FQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN---------------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKS--EQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            F FQAE+ ++M LIIN+ Y+NKEIFLRELISNASDALDKIR+ SLTDPS L +  EL I I  +     L ++DTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ V VI+K+N+D+QY WES +  +F+V  D  G  +GRGT+++L LK   +EYLE   ++ +V+++SQ++ +PI L+  K  E+                         K  +V +D +DD       +  K             D E +N  KPIWTR P ++++EEY EF+K+L    +  L+  HF+ EG++ F++LL+IP +AP +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K +V+K L++  +L    E + KF++ F   +K+G+ ED TNR RL++L++ H+S+S   +T+ +EYVSRMK  Q+ IYYI  E+ EQ  NS F+E+  K  +EV++ T+ +DE+ +  +++++G  L ++ + G+   + E  K ++   K +F  L   +K  ++     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   ++N +  ++KL 
Sbjct:   15 FAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI-------DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKK---VEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVL-----LFETALLSSGFSLEDPQTHSNRIYRMIKLG 687          
BLAST of Endoplasmin vs. Ensembl Human
Match: HSP90AB1 (heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258])

HSP 1 Score: 497.278 bits (1279), Expect = 5.525e-164
Identity = 284/697 (40.75%), Postives = 435/697 (62.41%), Query Frame = 3
Query:  348 FQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN---------------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKS--EQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            F FQAE+ ++M LIIN+ Y+NKEIFLRELISNASDALDKIR+ SLTDPS L +  EL I I  +     L ++DTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ V VI+K+N+D+QY WES +  +F+V  D  G  +GRGT+++L LK   +EYLE   ++ +V+++SQ++ +PI L+  K  E+                         K  +V +D +DD       +  K             D E +N  KPIWTR P ++++EEY EF+K+L    +  L+  HF+ EG++ F++LL+IP +AP +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K +V+K L++  +L    E + KF++ F   +K+G+ ED TNR RL++L++ H+S+S   +T+ +EYVSRMK  Q+ IYYI  E+ EQ  NS F+E+  K  +EV++ T+ +DE+ +  +++++G  L ++ + G+   + E  K ++   K +F  L   +K  ++     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   ++N +  ++KL 
Sbjct:   15 FAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI-------DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKK---VEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVL-----LFETALLSSGFSLEDPQTHSNRIYRMIKLG 687          
BLAST of Endoplasmin vs. Ensembl Human
Match: HSP90AB1 (heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258])

HSP 1 Score: 497.278 bits (1279), Expect = 5.525e-164
Identity = 284/697 (40.75%), Postives = 435/697 (62.41%), Query Frame = 3
Query:  348 FQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN---------------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKS--EQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            F FQAE+ ++M LIIN+ Y+NKEIFLRELISNASDALDKIR+ SLTDPS L +  EL I I  +     L ++DTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ V VI+K+N+D+QY WES +  +F+V  D  G  +GRGT+++L LK   +EYLE   ++ +V+++SQ++ +PI L+  K  E+                         K  +V +D +DD       +  K             D E +N  KPIWTR P ++++EEY EF+K+L    +  L+  HF+ EG++ F++LL+IP +AP +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K +V+K L++  +L    E + KF++ F   +K+G+ ED TNR RL++L++ H+S+S   +T+ +EYVSRMK  Q+ IYYI  E+ EQ  NS F+E+  K  +EV++ T+ +DE+ +  +++++G  L ++ + G+   + E  K ++   K +F  L   +K  ++     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   ++N +  ++KL 
Sbjct:   15 FAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI-------DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKK---VEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVL-----LFETALLSSGFSLEDPQTHSNRIYRMIKLG 687          
BLAST of Endoplasmin vs. Ensembl Human
Match: HSP90AB1 (heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258])

HSP 1 Score: 497.278 bits (1279), Expect = 5.525e-164
Identity = 284/697 (40.75%), Postives = 435/697 (62.41%), Query Frame = 3
Query:  348 FQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN---------------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKS--EQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            F FQAE+ ++M LIIN+ Y+NKEIFLRELISNASDALDKIR+ SLTDPS L +  EL I I  +     L ++DTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ V VI+K+N+D+QY WES +  +F+V  D  G  +GRGT+++L LK   +EYLE   ++ +V+++SQ++ +PI L+  K  E+                         K  +V +D +DD       +  K             D E +N  KPIWTR P ++++EEY EF+K+L    +  L+  HF+ EG++ F++LL+IP +AP +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K +V+K L++  +L    E + KF++ F   +K+G+ ED TNR RL++L++ H+S+S   +T+ +EYVSRMK  Q+ IYYI  E+ EQ  NS F+E+  K  +EV++ T+ +DE+ +  +++++G  L ++ + G+   + E  K ++   K +F  L   +K  ++     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   ++N +  ++KL 
Sbjct:   15 FAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI-------DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKK---VEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVL-----LFETALLSSGFSLEDPQTHSNRIYRMIKLG 687          
BLAST of Endoplasmin vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 644.81 bits (1662), Expect = 0.000e+0
Identity = 345/693 (49.78%), Postives = 467/693 (67.39%), Query Frame = 3
Query:  282 EAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKT--ENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKD-SSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILK 2351
            ++IKLDGLS +Q+KE+R KAEK +FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR +SLTDP  L    E+S+KIKAD+ N +L I DTG+GMTR +L+  LGTIA+SGT+EFLSK+    T  +   D IGQFGVGFY+ +LVAD V V +KNN+DDQYIWESDS+ +F+++KDPRGNTL RGT+I L LK  A+++LE + L+ LV +YSQ+++F I+LW SKT          E  A ++D             +    K     WDWE++N+ KPIW RKP +V E+EY +F+K++ K  ++PLS +HF+AEGEVSF+S+LY+P K+P ++F+   K   +I+LYVRRVFITD   D++P+YLSFI GIVDSDDLPLNVSRE LQQ KLLKVI+KKLVRKVLDM+KKL   QF  FW EF   IK+G++ED +NR RL KL++  SS      TT A YV RMK +Q+ IYY+   + ++ + SPF+E+ +   YEVLF T+ +DE+ +  M +YE  K  N+A+ G+  D  E +K      + EF+PL D++K      K+ IE  V++ RLV +P  +V    GW+GNMER+ +SQ+  + +      +   KK  EINP       +  L+        D    + A+ L ETA + SG+ + D   +A+ +E +L+
Sbjct:   42 DSIKLDGLSVSQIKELRSKAEKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSA-SFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFLWQSKTEMVEE--AVEEEPATTEDGAVEEEK-----EEKKTKKVEKTTWDWEKVNNVKPIWMRKPNQVEEDEYKQFYKSITKDSEEPLSHVHFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQHKLLKVIKKKLVRKVLDMLKKLDGAQFDDFWSEFSTNIKLGVMEDPSNRMRLAKLLRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEGVTIDDGEKAKEAHKGLEEEFKPLTDWLKE--TALKDLIEKAVVSQRLVKSPSALVASSYGWSGNMERIMKSQAYAKAKDPTQDFYATQKKTFEINP---RHPVIKELLKRVTASEEDTTAASTAKLLFETATLRSGFSLQDQVGFADRIEAVLR 721          
BLAST of Endoplasmin vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 644.81 bits (1662), Expect = 0.000e+0
Identity = 345/693 (49.78%), Postives = 467/693 (67.39%), Query Frame = 3
Query:  282 EAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKT--ENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKD-SSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILK 2351
            ++IKLDGLS +Q+KE+R KAEK +FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR +SLTDP  L    E+S+KIKAD+ N +L I DTG+GMTR +L+  LGTIA+SGT+EFLSK+    T  +   D IGQFGVGFY+ +LVAD V V +KNN+DDQYIWESDS+ +F+++KDPRGNTL RGT+I L LK  A+++LE + L+ LV +YSQ+++F I+LW SKT          E  A ++D             +    K     WDWE++N+ KPIW RKP +V E+EY +F+K++ K  ++PLS +HF+AEGEVSF+S+LY+P K+P ++F+   K   +I+LYVRRVFITD   D++P+YLSFI GIVDSDDLPLNVSRE LQQ KLLKVI+KKLVRKVLDM+KKL   QF  FW EF   IK+G++ED +NR RL KL++  SS      TT A YV RMK +Q+ IYY+   + ++ + SPF+E+ +   YEVLF T+ +DE+ +  M +YE  K  N+A+ G+  D  E +K      + EF+PL D++K      K+ IE  V++ RLV +P  +V    GW+GNMER+ +SQ+  + +      +   KK  EINP       +  L+        D    + A+ L ETA + SG+ + D   +A+ +E +L+
Sbjct:   42 DSIKLDGLSVSQIKELRSKAEKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSA-SFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFLWQSKTEMVEE--AVEEEPATTEDGAVEEEK-----EEKKTKKVEKTTWDWEKVNNVKPIWMRKPNQVEEDEYKQFYKSITKDSEEPLSHVHFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQHKLLKVIKKKLVRKVLDMLKKLDGAQFDDFWSEFSTNIKLGVMEDPSNRMRLAKLLRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEGVTIDDGEKAKEAHKGLEEEFKPLTDWLKE--TALKDLIEKAVVSQRLVKSPSALVASSYGWSGNMERIMKSQAYAKAKDPTQDFYATQKKTFEINP---RHPVIKELLKRVTASEEDTTAASTAKLLFETATLRSGFSLQDQVGFADRIEAVLR 721          
BLAST of Endoplasmin vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 603.594 bits (1555), Expect = 0.000e+0
Identity = 324/662 (48.94%), Postives = 439/662 (66.31%), Query Frame = 3
Query:  375 MMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKT--ENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKD-SSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILK 2351
            MMKLIINSLY NKEIFLRELISNASDALDKIR +SLTDP  L    E+S+KIKAD+ N +L I DTG+GMTR +L+  LGTIA+SGT+EFLSK+    T  +   D IGQFGVGFY+ +LVAD V V +KNN+DDQYIWESDS+ +F+++KDPRGNTL RGT+I L LK  A+++LE + L+ LV +YSQ+++F I+LW SKT          E  A ++D             +    K     WDWE++N+ KPIW RKP +V E+EY +F+K++ K  ++PLS +HF+AEGEVSF+S+LY+P K+P ++F+   K   +I+LYVRRVFITD   D++P+YLSFI GIVDSDDLPLNVSRE LQQ KLLKVI+KKLVRKVLDM+KKL   QF  FW EF   IK+G++ED +NR RL KL++  SS      TT A YV RMK +Q+ IYY+   + ++ + SPF+E+ +   YEVLF T+ +DE+ +  M +YE  K  N+A+ G+  D  E +K      + EF+PL D++K      K+ IE  V++ RLV +P  +V    GW+GNMER+ +SQ+  + +      +   KK  EINP       +  L+        D    + A+ L ETA + SG+ + D   +A+ +E +L+
Sbjct:    1 MMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSA-SFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFLWQSKTEMVEE--AVEEEPATTEDGAVEEEK-----EEKKTKKVEKTTWDWEKVNNVKPIWMRKPNQVEEDEYKQFYKSITKDSEEPLSHVHFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQHKLLKVIKKKLVRKVLDMLKKLDGAQFDDFWSEFSTNIKLGVMEDPSNRMRLAKLLRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEGVTIDDGEKAKEAHKGLEEEFKPLTDWLKE--TALKDLIEKAVVSQRLVKSPSALVASSYGWSGNMERIMKSQAYAKAKDPTQDFYATQKKTFEINP---RHPVIKELLKRVTASEEDTTAASTAKLLFETATLRSGFSLQDQVGFADRIEAVLR 649          
BLAST of Endoplasmin vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 603.594 bits (1555), Expect = 0.000e+0
Identity = 324/662 (48.94%), Postives = 439/662 (66.31%), Query Frame = 3
Query:  375 MMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKT--ENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKD-SSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILK 2351
            MMKLIINSLY NKEIFLRELISNASDALDKIR +SLTDP  L    E+S+KIKAD+ N +L I DTG+GMTR +L+  LGTIA+SGT+EFLSK+    T  +   D IGQFGVGFY+ +LVAD V V +KNN+DDQYIWESDS+ +F+++KDPRGNTL RGT+I L LK  A+++LE + L+ LV +YSQ+++F I+LW SKT          E  A ++D             +    K     WDWE++N+ KPIW RKP +V E+EY +F+K++ K  ++PLS +HF+AEGEVSF+S+LY+P K+P ++F+   K   +I+LYVRRVFITD   D++P+YLSFI GIVDSDDLPLNVSRE LQQ KLLKVI+KKLVRKVLDM+KKL   QF  FW EF   IK+G++ED +NR RL KL++  SS      TT A YV RMK +Q+ IYY+   + ++ + SPF+E+ +   YEVLF T+ +DE+ +  M +YE  K  N+A+ G+  D  E +K      + EF+PL D++K      K+ IE  V++ RLV +P  +V    GW+GNMER+ +SQ+  + +      +   KK  EINP       +  L+        D    + A+ L ETA + SG+ + D   +A+ +E +L+
Sbjct:    1 MMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSA-SFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFLWQSKTEMVEE--AVEEEPATTEDGAVEEEK-----EEKKTKKVEKTTWDWEKVNNVKPIWMRKPNQVEEDEYKQFYKSITKDSEEPLSHVHFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQHKLLKVIKKKLVRKVLDMLKKLDGAQFDDFWSEFSTNIKLGVMEDPSNRMRLAKLLRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEGVTIDDGEKAKEAHKGLEEEFKPLTDWLKE--TALKDLIEKAVVSQRLVKSPSALVASSYGWSGNMERIMKSQAYAKAKDPTQDFYATQKKTFEINP---RHPVIKELLKRVTASEEDTTAASTAKLLFETATLRSGFSLQDQVGFADRIEAVLR 649          
BLAST of Endoplasmin vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 603.594 bits (1555), Expect = 0.000e+0
Identity = 324/662 (48.94%), Postives = 439/662 (66.31%), Query Frame = 3
Query:  375 MMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKT--ENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKD-SSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILK 2351
            MMKLIINSLY NKEIFLRELISNASDALDKIR +SLTDP  L    E+S+KIKAD+ N +L I DTG+GMTR +L+  LGTIA+SGT+EFLSK+    T  +   D IGQFGVGFY+ +LVAD V V +KNN+DDQYIWESDS+ +F+++KDPRGNTL RGT+I L LK  A+++LE + L+ LV +YSQ+++F I+LW SKT          E  A ++D             +    K     WDWE++N+ KPIW RKP +V E+EY +F+K++ K  ++PLS +HF+AEGEVSF+S+LY+P K+P ++F+   K   +I+LYVRRVFITD   D++P+YLSFI GIVDSDDLPLNVSRE LQQ KLLKVI+KKLVRKVLDM+KKL   QF  FW EF   IK+G++ED +NR RL KL++  SS      TT A YV RMK +Q+ IYY+   + ++ + SPF+E+ +   YEVLF T+ +DE+ +  M +YE  K  N+A+ G+  D  E +K      + EF+PL D++K      K+ IE  V++ RLV +P  +V    GW+GNMER+ +SQ+  + +      +   KK  EINP       +  L+        D    + A+ L ETA + SG+ + D   +A+ +E +L+
Sbjct:    1 MMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDSA-SFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFLWQSKTEMVEE--AVEEEPATTEDGAVEEEK-----EEKKTKKVEKTTWDWEKVNNVKPIWMRKPNQVEEDEYKQFYKSITKDSEEPLSHVHFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQHKLLKVIKKKLVRKVLDMLKKLDGAQFDDFWSEFSTNIKLGVMEDPSNRMRLAKLLRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEGVTIDDGEKAKEAHKGLEEEFKPLTDWLKE--TALKDLIEKAVVSQRLVKSPSALVASSYGWSGNMERIMKSQAYAKAKDPTQDFYATQKKTFEINP---RHPVIKELLKRVTASEEDTTAASTAKLLFETATLRSGFSLQDQVGFADRIEAVLR 649          
BLAST of Endoplasmin vs. Ensembl Fly
Match: Gp93 (gene:FBgn0039562 transcript:FBtr0085254)

HSP 1 Score: 643.654 bits (1659), Expect = 0.000e+0
Identity = 350/709 (49.37%), Postives = 487/709 (68.69%), Query Frame = 3
Query:  246 SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIE---KEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTN---EVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER-EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILK 2351
            S+TD E ++REEEAI+LDGL+ AQLKE+R+KA+KF FQ EV+RMMKLIINSLY NKEIFLRELISNASDA+DKIR ++L++   L   PEL I+IKADK N  L I+D+GIGMT  +L+  LGTIAKSGT +FL+K++   K +  + +D IGQFGVGFYS +LVAD V V +K+N+D QYIWESD +N+FS+T+DPRG+TL RG+ I L LK  A ++LE + +R L+R+YSQ+++FPI +W+SKT EE    +     E   D  +DE A V +E         K S   WDW  IN  KPIWTRKPAEV+E+EY  F+K+L K   +PL++ HF AEGEV+FKSLLY+P   P+  F R   K  +I+LYVRRVFITD+  D++P YLSFI G+VDSDDLPLNVSRETLQQ KL+KVI+KKLVRKVLDM+KK+  E + KFWKEF   IK+G++ED +NR+RL KL++  +S     +T+ AEY  RMK++QE IYYI   N  + + SPF+E+ L   YEVL+  + +DE+ +  + +++G K  N+A+ G   +++E SK    + K+ F PL+ ++  D+   K+ I    +++RL ++P  +V    GWTGNMERLA S + ++ +      ++  KK LEINP       +  L+       +D    + A  +  TA + SGY++ + +++A+ +E +++
Sbjct:   41 SRTDAETLKREEEAIQLDGLNVAQLKEIREKAKKFTFQTEVNRMMKLIINSLYRNKEIFLRELISNASDAIDKIRLLALSNSKELETNPELHIRIKADKENKALHIMDSGIGMTHQDLINNLGTIAKSGTADFLAKMQDPSKSEGLDMNDMIGQFGVGFYSAFLVADRVVVTTKHNDDKQYIWESD-ANSFSITEDPRGDTLKRGSVISLYLKEEAQDFLEEDTVRELIRKYSQFINFPIRMWSSKTVEEEVPVEEEAKPEKSEDDVEDEDAKV-EEAEDEKPKTKKVSKTTWDWTLINDSKPIWTRKPAEVTEDEYTSFYKSLTKDSSEPLTQTHFIAEGEVTFKSLLYVPKVQPSESFNRYGTKSDNIKLYVRRVFITDEFNDMMPNYLSFIRGVVDSDDLPLNVSRETLQQHKLIKVIKKKLVRKVLDMLKKIDKEAYEKFWKEFSTNIKLGVMEDPSNRSRLAKLLRFQTSNG-KGVTSLAEYKERMKAKQEHIYYIAGANRAEVEKSPFVERLLSKGYEVLYLVEAVDEYCISALPEFDGKKFQNVAKEGFQLNESEKSKKNFESLKSTFEPLVKWL-NDV-ALKDQISKAQVSERLSNSPCALVAGVFGWTGNMERLAMSNAHQKSDDPQRTYYLNQKKTLEINP---RHPLMRELLRRVEADEADDTAKDMAVMMFRTATLRSGYMLQETSQFADSIEQMMR 741          
BLAST of Endoplasmin vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0332873)

HSP 1 Score: 504.982 bits (1299), Expect = 2.332e-167
Identity = 281/695 (40.43%), Postives = 432/695 (62.16%), Query Frame = 3
Query:  327 MRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDE--------------EXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLK--SEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            M ++AE F FQAE+ ++M LIIN+ Y+NKEIFLRELISNASDALDKIR+ SLTDPS L +  EL IK+  +K    L IIDTGIGMT+ +LV  LGTIAKSGT  F+  ++          IGQFGVGFYS YLVAD VTV SKNN+D+QY+WES +  +F+V  D     LGRGT+IVL +K   ++YLE   ++ +V ++SQ++ +PI L   K  E+       + +    D++    TDE              + K             + E +N  KPIWTR P ++S+EEY EF+K+L    +  L+  HF+ EG++ F++LL+IP + P +LFE + K ++I+LYVRRVFI D   D+IP YL+F+ G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K +++I++L    E + KF+ +F   +K+G+ ED  NR +L   ++ H+S S  +  + A+YVSRMK  Q+ +Y+I  E+ +Q  NS F+E+     +EV++ T+ +DE+ +  +++Y+G +L ++ + G+   + E  K +    K +F  L   +K+ ++     +E +V+++RLV +P  +V    GW+ NMER+ ++Q+ +   +     ++  KK LEINP HPI+  L    +   N ++  DL+++     L ET+++SSG+ +     +A+ +  ++KL 
Sbjct:    1 MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQ---AGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRAD-NSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNK---VEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTAT---MGYMAGKKQLEINPDHPIVETLRQKADADKNDKAVKDLVIL-----LFETSLLSSGFSLDSPQVHASRIYRMIKLG 680          
BLAST of Endoplasmin vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0073040)

HSP 1 Score: 504.982 bits (1299), Expect = 2.332e-167
Identity = 281/695 (40.43%), Postives = 432/695 (62.16%), Query Frame = 3
Query:  327 MRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDE--------------EXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLK--SEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            M ++AE F FQAE+ ++M LIIN+ Y+NKEIFLRELISNASDALDKIR+ SLTDPS L +  EL IK+  +K    L IIDTGIGMT+ +LV  LGTIAKSGT  F+  ++          IGQFGVGFYS YLVAD VTV SKNN+D+QY+WES +  +F+V  D     LGRGT+IVL +K   ++YLE   ++ +V ++SQ++ +PI L   K  E+       + +    D++    TDE              + K             + E +N  KPIWTR P ++S+EEY EF+K+L    +  L+  HF+ EG++ F++LL+IP + P +LFE + K ++I+LYVRRVFI D   D+IP YL+F+ G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K +++I++L    E + KF+ +F   +K+G+ ED  NR +L   ++ H+S S  +  + A+YVSRMK  Q+ +Y+I  E+ +Q  NS F+E+     +EV++ T+ +DE+ +  +++Y+G +L ++ + G+   + E  K +    K +F  L   +K+ ++     +E +V+++RLV +P  +V    GW+ NMER+ ++Q+ +   +     ++  KK LEINP HPI+  L    +   N ++  DL+++     L ET+++SSG+ +     +A+ +  ++KL 
Sbjct:    1 MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQ---AGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRAD-NSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKEGDEKKEMETDEPKIEDVGEDEDADKKDKDAKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNK---VEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTAT---MGYMAGKKQLEINPDHPIVETLRQKADADKNDKAVKDLVIL-----LFETSLLSSGFSLDSPQVHASRIYRMIKLG 680          
BLAST of Endoplasmin vs. Ensembl Fly
Match: Trap1 (gene:FBgn0026761 transcript:FBtr0086149)

HSP 1 Score: 281.952 bits (720), Expect = 6.826e-83
Identity = 195/637 (30.61%), Postives = 333/637 (52.28%), Query Frame = 3
Query:  342 EKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLT--DPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI----EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNN--NDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREI-KDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLK----VIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLI--EDDTNRNRLTKLIQMHSSKS--LANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLAR--------GGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINP 2177
            +K +FQAE  +++ ++  SLY++ E+F+RELISNASDAL+K R+ SL+    ++ G    L I+I  DK    L I DTGIGMT++ELV  LGTIA+SG+ +FL ++    +   +E +S+ IGQFGVGFYS ++VA+ V V ++    N     W +D S T+ + + P    +  GT IVL LK    EY + E ++ ++++YS ++  PI L         + K+ NE+                                       KP+W  +P  +S+E++++F++ +  S D P   +H+NA+  +S  +LLY P   P  LFE     ++ + LY R+V I  K   ++P++L F+ G+VDS+D+PLN+SRE LQ   L++    VI  +++R + +  KK + E++  F++++   +K G++   D + +  + KL++  SSKS   +   +  EY + + ++Q+ IYY+   N   A++SP+ E   K +  VLF  +  DE  L  + K++  KL ++ +             D  EGS  R     +E   LI +++ ++   +  +  +  T RL + P ++  ++     +  R    Q  +Q    ++Q        LEINP
Sbjct:   64 DKHEFQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEVP---DVELGTRIVLHLKTDCREYADEERIKAVIKKYSNFVGSPILL---------NGKQANEI---------------------------------------KPLWLLEPQSISKEQHHDFYRFISNSFDVPRFTLHYNADVPLSIHALLYFPEGKPG-LFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQNSSLIRKLSSVISTRVIRFLQERSKK-QPEEYEAFYRDYGLFLKEGIVTSSDASEKEEIAKLLRFESSKSETASGRMSLEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKRNELVLFCYEPYDELVLMQLGKFKSKKLVSVEKEMREESKETTATTDFGEGSLLR-----SELDTLIPWLEEEL---RGQVIKVKATTRLDTHPCVITVEEMAAARHFIRTQSHQVPEQNRFALLQ------PELEINP 633          
BLAST of Endoplasmin vs. Ensembl Fly
Match: Trap1 (gene:FBgn0026761 transcript:FBtr0336666)

HSP 1 Score: 281.952 bits (720), Expect = 6.826e-83
Identity = 195/637 (30.61%), Postives = 333/637 (52.28%), Query Frame = 3
Query:  342 EKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLT--DPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI----EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNN--NDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREI-KDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLK----VIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLI--EDDTNRNRLTKLIQMHSSKS--LANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLAR--------GGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINP 2177
            +K +FQAE  +++ ++  SLY++ E+F+RELISNASDAL+K R+ SL+    ++ G    L I+I  DK    L I DTGIGMT++ELV  LGTIA+SG+ +FL ++    +   +E +S+ IGQFGVGFYS ++VA+ V V ++    N     W +D S T+ + + P    +  GT IVL LK    EY + E ++ ++++YS ++  PI L         + K+ NE+                                       KP+W  +P  +S+E++++F++ +  S D P   +H+NA+  +S  +LLY P   P  LFE     ++ + LY R+V I  K   ++P++L F+ G+VDS+D+PLN+SRE LQ   L++    VI  +++R + +  KK + E++  F++++   +K G++   D + +  + KL++  SSKS   +   +  EY + + ++Q+ IYY+   N   A++SP+ E   K +  VLF  +  DE  L  + K++  KL ++ +             D  EGS  R     +E   LI +++ ++   +  +  +  T RL + P ++  ++     +  R    Q  +Q    ++Q        LEINP
Sbjct:   64 DKHEFQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEVP---DVELGTRIVLHLKTDCREYADEERIKAVIKKYSNFVGSPILL---------NGKQANEI---------------------------------------KPLWLLEPQSISKEQHHDFYRFISNSFDVPRFTLHYNADVPLSIHALLYFPEGKPG-LFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQNSSLIRKLSSVISTRVIRFLQERSKK-QPEEYEAFYRDYGLFLKEGIVTSSDASEKEEIAKLLRFESSKSETASGRMSLEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKRNELVLFCYEPYDELVLMQLGKFKSKKLVSVEKEMREESKETTATTDFGEGSLLR-----SELDTLIPWLEEEL---RGQVIKVKATTRLDTHPCVITVEEMAAARHFIRTQSHQVPEQNRFALLQ------PELEINP 633          
BLAST of Endoplasmin vs. Ensembl Zebrafish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 687.567 bits (1773), Expect = 0.000e+0
Identity = 374/731 (51.16%), Postives = 516/731 (70.59%), Query Frame = 3
Query:  204 DNEIKLKKTMKEPL------SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIE--KEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTS--EENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            D+++ +  T++E L      S+TDDEV++REEEAI+LDGL+ +QLKE+R KAEK  FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR +SLT+   L    EL+IKIK+DK  NML I DTGIGMT++ELVK LGTIAKSGT+EFL+K+   ++ +++TS+ IGQFGVGFYS +LVAD V V SK+NND Q++WESD SN FSV +DPRG+TLGRGT I L +K  AS+YLE E ++ LV++YSQ+++FPIY+W+SKT   EE    +    K ++ +DE+    +EE K      K    VWDWE +N  KPIW R   EV E+EY  F+KT  +  D+PLS IHF AEGEV+FKS+L++P+ AP  LF+     K+  I+L+VRRVFITD   D++P+YL+FI G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  EQ+  KFWKEF   IK+G+IED +NR RL KL++  +S S   L++  +YV RMK +Q++IY++   + ++A++SPF+EK LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD+++ +K +    + EF PL  ++K   +  KE IE  VL+ RL ++P  +V    GW+GNMER+ ++Q+ +  +      +   KK LEINPKHP+I ++   +N  A  ++     + A  L ETA + SGY + D   Y   +E +L+L+
Sbjct:   22 DDDVDIDGTVEEDLGKSRDGSRTDDEVVQREEEAIQLDGLNTSQLKEIRDKAEKHAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLLSLTNEDALAGNEELTIKIKSDKEKNMLHITDTGIGMTKEELVKNLGTIAKSGTSEFLNKMTEVQDDSQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHMWESD-SNQFSVIEDPRGDTLGRGTTITLVMKEEASDYLELETIKNLVKKYSQFINFPIYVWSSKTETVEEPIEDEAEAEKEEATEDEAEVEEEEEDKDKPKTKKVEKTVWDWELMNDIKPIWQRPAKEVEEDEYTAFYKTFSRDTDEPLSHIHFTAEGEVTFKSILFVPASAPRGLFDEYGTKKNDFIKLFVRRVFITDDFHDMMPKYLNFIKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEEQYNDKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQTSHSDTVLSSLEQYVERMKEKQDKIYFMAGTSRKEAESSPFVEKLLKKGYEVVYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESDKAKEKREALEKEFEPLTTWMKD--KALKEQIEKAVLSQRLTNSPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTLEINPKHPLIKEMLRRVNEDAEDKT---AADLAVVLFETATLRSGYQLQDTKAYGERIERMLRLS 746          
BLAST of Endoplasmin vs. Ensembl Zebrafish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 686.797 bits (1771), Expect = 0.000e+0
Identity = 370/711 (52.04%), Postives = 506/711 (71.17%), Query Frame = 3
Query:  246 SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIE--KEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTS--EENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            S+TDDEV++REEEAI+LDGL+ +QLKE+R KAEK  FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR +SLT+   L    EL+IKIK+DK  NML I DTGIGMT++ELVK LGTIAKSGT+EFL+K+   ++ +++TS+ IGQFGVGFYS +LVAD V V SK+NND Q++WESD SN FSV +DPRG+TLGRGT I L +K  AS+YLE E ++ LV++YSQ+++FPIY+W+SKT   EE    +    K ++ +DE+    +EE K      K    VWDWE +N  KPIW R   EV E+EY  F+KT  +  D+PLS IHF AEGEV+FKS+L++P+ AP  LF+     K+  I+L+VRRVFITD   D++P+YL+FI G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  EQ+  KFWKEF   IK+G+IED +NR RL KL++  +S S   L++  +YV RMK +Q++IY++   + ++A++SPF+EK LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD+++ +K +    + EF PL  ++K   +  KE IE  VL+ RL ++P  +V    GW+GNMER+ ++Q+ +  +      +   KK LEINPKHP+I ++   +N  A  ++     + A  L ETA + SGY + D   Y   +E +L+L+
Sbjct:   43 SRTDDEVVQREEEAIQLDGLNTSQLKEIRDKAEKHAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLLSLTNEDALAGNEELTIKIKSDKEKNMLHITDTGIGMTKEELVKNLGTIAKSGTSEFLNKMTEVQDDSQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHMWESD-SNQFSVIEDPRGDTLGRGTTITLVMKEEASDYLELETIKNLVKKYSQFINFPIYVWSSKTETVEEPIEDEAEAEKEEATEDEAEVEEEEEDKDKPKTKKVEKTVWDWELMNDIKPIWQRPAKEVEEDEYTAFYKTFSRDTDEPLSHIHFTAEGEVTFKSILFVPASAPRGLFDEYGTKKNDFIKLFVRRVFITDDFHDMMPKYLNFIKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEEQYNDKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQTSHSDTVLSSLEQYVERMKEKQDKIYFMAGTSRKEAESSPFVEKLLKKGYEVVYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESDKAKEKREALEKEFEPLTTWMKD--KALKEQIEKAVLSQRLTNSPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTLEINPKHPLIKEMLRRVNEDAEDKT---AADLAVVLFETATLRSGYQLQDTKAYGERIERMLRLS 747          
BLAST of Endoplasmin vs. Ensembl Zebrafish
Match: hsp90aa1.1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 [Source:NCBI gene;Acc:30591])

HSP 1 Score: 509.605 bits (1311), Expect = 5.784e-169
Identity = 284/703 (40.40%), Postives = 436/703 (62.02%), Query Frame = 3
Query:  327 MRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSK--------------------TSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            M ++ E F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPS L +  +L I++  D+    L IIDTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ VTVI+K+N+D+QYIWES +  +F+V  D  G ++GRGT+++L LK   SEY+E + ++ +V+++SQ++ +PI L+  K                      E+    K  ++ AD  +D                 K      D + +N  KPIWTR P +++ EEY EF+K+L    +  L+  HF+ EG++ F++LL++P +A  +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K LD+  +L  ++  + K++++F   IK+G+ ED  NR +L+ L++ ++S S   + +  +YVSRMK  Q+ IYYI  E  +Q  NS F+E+  K   EV++  + +DE+ +  +++Y+G  L ++ + G+   + E  K + +  K ++  L   +K DI   K  IE + +++RLVS+P  +V    GWT NMER+ +SQ+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   +AN +  ++KL 
Sbjct:   10 MEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPD-FGESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEVDLEEGEKQEEEEVAAGEDKDKPKIEDLGADEDEDSKDGKN-------KRKKKVKEKYIDAQELNKTKPIWTRNPDDITNEEYGEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLDLFTELAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSDLLRYYTSASGDEMVSLKDYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGLELPEDEEEKKKQDELKAKYENLCKIMK-DILDKK--IEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKSQALRDNST---MGYMTAKKHLEINPAHPIVETLREKAEADKNDKAVKDLVIL-----LFETALLSSGFTLDDPQTHANRIYRMIKLG 688          
BLAST of Endoplasmin vs. Ensembl Zebrafish
Match: hsp90aa1.1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 [Source:NCBI gene;Acc:30591])

HSP 1 Score: 509.605 bits (1311), Expect = 5.784e-169
Identity = 284/703 (40.40%), Postives = 436/703 (62.02%), Query Frame = 3
Query:  327 MRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSK--------------------TSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            M ++ E F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPS L +  +L I++  D+    L IIDTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ VTVI+K+N+D+QYIWES +  +F+V  D  G ++GRGT+++L LK   SEY+E + ++ +V+++SQ++ +PI L+  K                      E+    K  ++ AD  +D                 K      D + +N  KPIWTR P +++ EEY EF+K+L    +  L+  HF+ EG++ F++LL++P +A  +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K LD+  +L  ++  + K++++F   IK+G+ ED  NR +L+ L++ ++S S   + +  +YVSRMK  Q+ IYYI  E  +Q  NS F+E+  K   EV++  + +DE+ +  +++Y+G  L ++ + G+   + E  K + +  K ++  L   +K DI   K  IE + +++RLVS+P  +V    GWT NMER+ +SQ+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   +AN +  ++KL 
Sbjct:   10 MEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPD-FGESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEVDLEEGEKQEEEEVAAGEDKDKPKIEDLGADEDEDSKDGKN-------KRKKKVKEKYIDAQELNKTKPIWTRNPDDITNEEYGEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLDLFTELAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSDLLRYYTSASGDEMVSLKDYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGLELPEDEEEKKKQDELKAKYENLCKIMK-DILDKK--IEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKSQALRDNST---MGYMTAKKHLEINPAHPIVETLREKAEADKNDKAVKDLVIL-----LFETALLSSGFTLDDPQTHANRIYRMIKLG 688          
BLAST of Endoplasmin vs. Ensembl Zebrafish
Match: hsp90ab1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 495.738 bits (1275), Expect = 1.607e-163
Identity = 279/690 (40.43%), Postives = 433/690 (62.75%), Query Frame = 3
Query:  348 FQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN--------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            F FQAE+ ++M LIIN+ Y+NKEIFLREL+SNASDALDKIR+ SLTDP+ L +  +L I I  +     L +IDTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ VTVI+K+N+D+QY WES +  +F+V  D  G  +GRGT+++L LK   +EY+E + ++ +V+++SQ++ +PI L+  K  ++                 ++  E K   +D  S    D + K      K      D E +N  KPIWTR P ++S EEY EF+K+L    +  L+  HF+ EG++ F++LL+IP +AP +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K +V+K L++  +L  ++  + KF+  F   +K+G+ ED  NR +L++L++  SS+S   +T+  EYVSRMK  Q+ IYYI  E+ +Q  +S F+E+  K  +EVL+ T+ +DE+ +  ++ ++G  L ++ + G+   + E  K ++   K +F  L   +K  ++     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   ++N +  ++KL 
Sbjct:   14 FAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVD-HGEPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLYVEKERDKEISDDEAEEEKAEKEEKEEEGEDKPKIEDVGSDDEEDTKDKDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGDEMTSLTEYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKK---VEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVIL-----LFETALLSSGFSLDDPQTHSNRIYRMIKLG 686          
BLAST of Endoplasmin vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 682.559 bits (1760), Expect = 0.000e+0
Identity = 371/732 (50.68%), Postives = 509/732 (69.54%), Query Frame = 3
Query:  186 LDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKT-SEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQF-GKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLNYK 2363
            +D+T+ED+  K +       S+TDDEV+ REEEAI++DGL+ AQ+KE+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL+IKIK DK  NML I DTGIGMT+++LVK LGTIAKSGT+EFLSK+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN F V  DPRG+TLGRGT I L LK  A++YLE E ++ LVR+YSQ+++FPIY+W+SKT + E  L +    + D + DE A V +E+ +      K    VWDWE +N  KPIW R   E+ E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L+IP+ AP  LF+     K   I+L+VRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  +++  KFWKEF   IK+G+IED +NR RL KL++  SS + +  T+  +YV RMK +Q++IY+I   + ++ ++SPF+E+ LK  YEVLF  + +DE+ +  + +++G +  N+A+ G+ FD+ E SK      + E+ PL+ ++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP+HP+I ++    N      +DL ++     L ETA + SGY + D   Y + +E +L+L+ K
Sbjct:   18 VDATVEDDIGKSRDG-----SRTDDEVVSREEEAIQIDGLNAAQIKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAANEELTIKIKCDKEKNMLHITDTGIGMTKEDLVKNLGTIAKSGTSEFLSKLTDAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESD-SNEFFVNDDPRGDTLGRGTTITLVLKEEATDYLELETIKNLVRKYSQFINFPIYVWSSKTETVEEPLDEEEAKEKDEETDEEAAVEEEDEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEIEEDEYKAFYKSFSKEADDPMAYIHFTAEGEVTFKSILFIPTTAPRGLFDEYGSKKSDFIKLFVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEDKYTDKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSNNKSETTSLEQYVERMKEKQDKIYFIAGASRKEVESSPFVERLLKKGYEVLFLIEPVDEYCIQALPEFDGKRFQNVAKEGLKFDENEKSKEAREALEKEYEPLLTWMKE--KALKDQIEKAVVSQRLTQSPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYSGQKKTFEINPRHPLIKEMLQRENEDDKTVADLAVV-----LFETATLRSGYHLPDTKSYGDRIERMLRLSLK 736          
BLAST of Endoplasmin vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 680.633 bits (1755), Expect = 0.000e+0
Identity = 367/732 (50.14%), Postives = 503/732 (68.72%), Query Frame = 3
Query:  186 LDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKT-SEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQF-GKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLNYK 2363
            +D+T+ED+  K +       S+TDDEV+ REEEAI++DGL+ AQ+KE+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL+IKIK DK  NML I DTGIGMT+++LVK LGTIAKSGT+EFLSK+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN F V  DPRG+TLGRGT I L LK  A++YLE E ++ LVR+YSQ+++FPIY+W+SKT + E  L +    + D + DE A V +E+ +      K    VWDWE +N  KPIW R   E+ E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L+IP+ AP  LF+     K   I+L+VRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  +++  KFWKEF   IK+G+IED +NR RL KL++  SS + +  T+  +YV RMK +Q++IY+I   + ++ ++SPF+E+ LK  YEVLF  + +DE+ +  + +++G +  N+A+ G+ FD+ E SK      + E+ PL+ ++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       +  ++        D  + + A  L ETA + SGY + D   Y + +E +L+L+ K
Sbjct:   27 VDATVEDDIGKSRDG-----SRTDDEVVSREEEAIQIDGLNAAQIKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAANEELTIKIKCDKEKNMLHITDTGIGMTKEDLVKNLGTIAKSGTSEFLSKLTDAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESD-SNEFFVNDDPRGDTLGRGTTITLVLKEEATDYLELETIKNLVRKYSQFINFPIYVWSSKTETVEEPLDEEEAKEKDEETDEEAAVEEEDEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEIEEDEYKAFYKSFSKEADDPMAYIHFTAEGEVTFKSILFIPTTAPRGLFDEYGSKKSDFIKLFVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEDKYTDKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSNNKSETTSLEQYVERMKEKQDKIYFIAGASRKEVESSPFVERLLKKGYEVLFLIEPVDEYCIQALPEFDGKRFQNVAKEGLKFDENEKSKEAREALEKEYEPLLTWMKE--KALKDQIEKAVVSQRLTQSPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYSGQKKTFEINP---RHPLIKEMLQRVKENEDDKTVADLAVVLFETATLRSGYHLPDTKSYGDRIERMLRLSLK 747          
BLAST of Endoplasmin vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 629.017 bits (1621), Expect = 0.000e+0
Identity = 330/602 (54.82%), Postives = 440/602 (73.09%), Query Frame = 3
Query:  186 LDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKT-SEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQF-GKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIK 1973
            +D+T+ED+  K +       S+TDDEV+ REEEAI++DGL+ AQ+KE+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL+IKIK DK  NML I DTGIGMT+++LVK LGTIAKSGT+EFLSK+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN F V  DPRG+TLGRGT I L LK  A++YLE E ++ LVR+YSQ+++FPIY+W+SKT + E  L +    + D + DE A V +E+ +      K    VWDWE +N  KPIW R   E+ E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L+IP+ AP  LF+     K   I+L+VRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  +++  KFWKEF   IK+G+IED +NR RL KL++  SS + +  T+  +YV RMK +Q++IY+I   + ++ ++SPF+E+ LK  YEVLF  + +DE+ +  + +++G +  N+A+ G+ FD+ E SK      + E+ PL+ ++K
Sbjct:   29 VDATVEDDIGKSRDG-----SRTDDEVVSREEEAIQIDGLNAAQIKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAANEELTIKIKCDKEKNMLHITDTGIGMTKEDLVKNLGTIAKSGTSEFLSKLTDAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESD-SNEFFVNDDPRGDTLGRGTTITLVLKEEATDYLELETIKNLVRKYSQFINFPIYVWSSKTETVEEPLDEEEAKEKDEETDEEAAVEEEDEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEIEEDEYKAFYKSFSKEADDPMAYIHFTAEGEVTFKSILFIPTTAPRGLFDEYGSKKSDFIKLFVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEDKYTDKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSNNKSETTSLEQYVERMKEKQDKIYFIAGASRKEVESSPFVERLLKKGYEVLFLIEPVDEYCIQALPEFDGKRFQNVAKEGLKFDENEKSKEAREALEKEYEPLLTWMK 624          
BLAST of Endoplasmin vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 628.246 bits (1619), Expect = 0.000e+0
Identity = 353/736 (47.96%), Postives = 484/736 (65.76%), Query Frame = 3
Query:  186 LDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKT-SEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLF-EREIKDSSIRLYV-----RRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQF-GKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLNYK 2363
            +D+T+ED+  K +       S+TDDEV+ REEEAI++DGL+ AQ+KE+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL+IKIK DK  NML I DTGIGMT+++LVK LGTIAKSGT+EFLSK+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN F V  DPRG+TLGRGT I L LK  A++YLE E ++ LVR+YSQ+++FPIY+W+SKT + E  L +    + D + DE A V +E+ +      K    VWDWE +N  KPIW R   E+ E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L+IP+ AP  LF E   K ++I L +        F    +    P Y           DLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  +++  KFWKEF   IK+G+IED +NR RL KL++  SS + +  T+  +YV RMK +Q++IY+I   + ++ ++SPF+E+ LK  YEVLF  + +DE+ +  + +++G +  N+A+ G+ FD+ E SK      + E+ PL+ ++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       +  ++        D  + + A  L ETA + SGY + D   Y + +E +L+L+ K
Sbjct:   27 VDATVEDDIGKSRDG-----SRTDDEVVSREEEAIQIDGLNAAQIKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAANEELTIKIKCDKEKNMLHITDTGIGMTKEDLVKNLGTIAKSGTSEFLSKLTDAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESD-SNEFFVNDDPRGDTLGRGTTITLVLKEEATDYLELETIKNLVRKYSQFINFPIYVWSSKTETVEEPLDEEEAKEKDEETDEEAAVEEEDEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEIEEDEYKAFYKSFSKEADDPMAYIHFTAEGEVTFKSILFIPTTAPRGLFDEYGSKKTNITLLIFCEFELFFFFFFSVSKFYPMY-----------DLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEDKYTDKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSNNKSETTSLEQYVERMKEKQDKIYFIAGASRKEVESSPFVERLLKKGYEVLFLIEPVDEYCIQALPEFDGKRFQNVAKEGLKFDENEKSKEAREALEKEYEPLLTWMKE--KALKDQIEKAVVSQRLTQSPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYSGQKKTFEINP---RHPLIKEMLQRVKENEDDKTVADLAVVLFETATLRSGYHLPDTKSYGDRIERMLRLSLK 740          
BLAST of Endoplasmin vs. Ensembl Xenopus
Match: hsp90b1 (heat shock protein 90kDa beta (Grp94), member 1 [Source:NCBI gene;Acc:734089])

HSP 1 Score: 624.394 bits (1609), Expect = 0.000e+0
Identity = 347/730 (47.53%), Postives = 479/730 (65.62%), Query Frame = 3
Query:  186 LDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKT-SEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQF-GKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLNYK 2363
            +D+T+ED+  K +       S+TDDEV+ REEEAI++DGL+ AQ+KE+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL+IKIK DK  NML I DTGIGMT+++LVK LGTIAKSGT+EFLSK+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN F V  DPRG+TLGRGT I L LK  A++YLE E ++ LVR+YSQ+++FPIY+W+SKT + E  L +    + D + DE A V +E+ +      K    VWDWE +N  KPIW R   E+ E+EY  F+K+  K + K    +  +  G +                           L+VRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  +++  KFWKEF   IK+G+IED +NR RL KL++  SS + +  T+  +YV RMK +Q++IY+I   + ++ ++SPF+E+ LK  YEVLF  + +DE+ +  + +++G +  N+A+ G+ FD+ E SK      + E+ PL+ ++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       +  ++        D  + + A  L ETA + SGY + D   Y + +E +L+L+ K
Sbjct:   29 VDATVEDDIGKSRDG-----SRTDDEVVSREEEAIQIDGLNAAQIKELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAANEELTIKIKCDKEKNMLHITDTGIGMTKEDLVKNLGTIAKSGTSEFLSKLTDAQEDGQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESD-SNEFFVNDDPRGDTLGRGTTITLVLKEEATDYLELETIKNLVRKYSQFINFPIYVWSSKTETVEEPLDEEEAKEKDEETDEEAAVEEEDEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEIEEDEYKAFYKSFSKVNRKCNPLLTVSRSGNM---------------------------LFVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEDKYTDKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSNNKSETTSLEQYVERMKEKQDKIYFIAGASRKEVESSPFVERLLKKGYEVLFLIEPVDEYCIQALPEFDGKRFQNVAKEGLKFDENEKSKEAREALEKEYEPLLTWMKE--KALKDQIEKAVVSQRLTQSPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYSGQKKTFEINP---RHPLIKEMLQRVKENEDDKTVADLAVVLFETATLRSGYHLPDTKSYGDRIERMLRLSLK 720          
BLAST of Endoplasmin vs. Ensembl Mouse
Match: Hsp90b1 (heat shock protein 90, beta (Grp94), member 1 [Source:MGI Symbol;Acc:MGI:98817])

HSP 1 Score: 692.189 bits (1785), Expect = 0.000e+0
Identity = 364/731 (49.79%), Postives = 508/731 (69.49%), Query Frame = 3
Query:  204 DNEIKLKKTMKEPL------SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTS--EENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            D+E+ +  T++E L      S+TDDEV++REEEAI+LDGL+ +Q++E+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL++KIK DK  N+L + DTG+GMTR+ELVK LGTIAKSGT+EFL+K+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN FSV  DPRGNTLGRGT I L LK  AS+YLE + ++ LVR+YSQ+++FPIY+W+SKT   EE   +     +   + D+ A V +EE +      K    VWDWE +N  KPIW R   EV E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L++P+ AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS    ++T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD++E +K      + EF PL++++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       + +++        D  +++ A  L ETA + SGYL+ D   Y + +E +L+L+
Sbjct:   22 DDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESD-SNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPIYVWSSKTETVEEPLEEDEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREATEKEFEPLLNWMKD--KALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINP---RHPLIRDMLRRIKEDEDDKTVMDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLS 746          
BLAST of Endoplasmin vs. Ensembl Mouse
Match: Hsp90ab1 (heat shock protein 90 alpha (cytosolic), class B member 1 [Source:MGI Symbol;Acc:MGI:96247])

HSP 1 Score: 499.204 bits (1284), Expect = 7.358e-165
Identity = 284/697 (40.75%), Postives = 435/697 (62.41%), Query Frame = 3
Query:  348 FQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN---------------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKS--EQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            F FQAE+ ++M LIIN+ Y+NKEIFLRELISNASDALDKIR+ SLTDPS L +  EL I I  +     L ++DTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ V VI+K+N+D+QY WES +  +F+V  D  G  +GRGT+++L LK   +EYLE   ++ +V+++SQ++ +PI L+  K  E+                         K  +V +D +DD       +  K             D E +N  KPIWTR P ++++EEY EF+K+L    +  L+  HF+ EG++ F++LL+IP +AP +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K +V+K L++  +L    E + KF++ F   +K+G+ ED TNR RL++L++ H+S+S   +T+ +EYVSRMK  Q+ IYYI  E+ EQ  NS F+E+  K  +EV++ T+ +DE+ +  +++++G  L ++ + G+   + E  K ++   K +F  L   +K  ++     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   ++N +  ++KL 
Sbjct:   15 FAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEKEEEDKEDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYI-------DQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKK---VEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVL-----LFETALLSSGFSLEDPQTHSNRIYRMIKLG 687          
BLAST of Endoplasmin vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 489.96 bits (1260), Expect = 3.986e-161
Identity = 283/699 (40.49%), Postives = 439/699 (62.80%), Query Frame = 3
Query:  333 KKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN-----------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXW-DWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKS--EQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            ++ E F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPS L +  EL I +   K +  L I+DTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ VTVI+K+N+D+QY WES +  +F+V  D  G  +GRGT+++L LK   +EYLE   ++ +V+++SQ++ +PI L+  K  ++                    +K ++ K + +D  S    +E+   D    KK    + D E +N  KPIWTR P +++ EEY EF+K+L    ++ L+  HF+ EG++ F++LL++P +AP +LFE   K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K L++  +L    E + KF+++F   IK+G+ ED  NR +L++L++ ++S S   + +  +Y +RMK  Q+ IY+I  E  +Q  NS F+E+  K+  EV++  + +DE+ +  ++++EG  L ++ + G+   + E  K +   KK +F  L   +K  +E     +E +V+++RLV++P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP H II  L        N +S  DL+++ Y     ETA++SSG+ + D   +AN +  ++KL 
Sbjct:   15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDT-GEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKK---VEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLY-----ETALLSSGFSLEDPQTHANRIYRMIKLG 696          
BLAST of Endoplasmin vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 489.96 bits (1260), Expect = 3.986e-161
Identity = 283/699 (40.49%), Postives = 439/699 (62.80%), Query Frame = 3
Query:  333 KKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN-----------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXW-DWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKS--EQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            ++ E F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPS L +  EL I +   K +  L I+DTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ VTVI+K+N+D+QY WES +  +F+V  D  G  +GRGT+++L LK   +EYLE   ++ +V+++SQ++ +PI L+  K  ++                    +K ++ K + +D  S    +E+   D    KK    + D E +N  KPIWTR P +++ EEY EF+K+L    ++ L+  HF+ EG++ F++LL++P +AP +LFE   K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K L++  +L    E + KF+++F   IK+G+ ED  NR +L++L++ ++S S   + +  +Y +RMK  Q+ IY+I  E  +Q  NS F+E+  K+  EV++  + +DE+ +  ++++EG  L ++ + G+   + E  K +   KK +F  L   +K  +E     +E +V+++RLV++P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP H II  L        N +S  DL+++ Y     ETA++SSG+ + D   +AN +  ++KL 
Sbjct:   15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDT-GEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEEKEEEKEKEEKESDDKPEIEDVGSDEEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKK---VEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLY-----ETALLSSGFSLEDPQTHANRIYRMIKLG 696          
BLAST of Endoplasmin vs. Ensembl Mouse
Match: Hsp90b1 (heat shock protein 90, beta (Grp94), member 1 [Source:MGI Symbol;Acc:MGI:98817])

HSP 1 Score: 308.531 bits (789), Expect = 1.580e-96
Identity = 149/325 (45.85%), Postives = 225/325 (69.23%), Query Frame = 3
Query: 1212 DKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINP 2177
            D P++ IHF AEGEV+FKS+L++P+ AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS    ++T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD++E +K      + EF PL++++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP
Sbjct:   43 DDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREATEKEFEPLLNWMKD--KALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINP 365          
BLAST of Endoplasmin vs. UniProt/SwissProt
Match: sp|Q95M18|ENPL_BOVIN (Endoplasmin OS=Bos taurus OX=9913 GN=HSP90B1 PE=2 SV=1)

HSP 1 Score: 697.582 bits (1799), Expect = 0.000e+0
Identity = 370/740 (50.00%), Postives = 518/740 (70.00%), Query Frame = 3
Query:  183 TLDSTIEDNEIKLKKTMKEPL------SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTS--EENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXR--SDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            T  S   D+E+ +  T++E L      S+TDDEV++REEEAI+LDGL+ +Q++E+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL++KIK DK  N+L + DTG+GMTR+ELVK LGTIAKSGT+EFL+K+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN FSV  DPRGNTLGRGT I L LK  AS+YLE + ++ LV++YSQ+++FPIY+W+SKT   EE + ++    +   + D+ A V +EE +      K    VWDWE +N  KPIW R   EV E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L++P+ AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS   +++T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD++E SK      + EF PL++++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP+HP+I  +   +    + +  SDL ++     L ETA + SGYL+ D   Y + +E +L+L+
Sbjct:   15 TFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESD-SNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPAEEEEAAKEDKEESDDEAAVEEEEDEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDMTSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKSKESREAVEKEFEPLLNWMKD--KALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRVKEDEDDKTVSDLAVV-----LFETATLRSGYLLPDTKAYGDRIERMLRLS 746          
BLAST of Endoplasmin vs. UniProt/SwissProt
Match: sp|P08113|ENPL_MOUSE (Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE=1 SV=2)

HSP 1 Score: 692.189 bits (1785), Expect = 0.000e+0
Identity = 364/731 (49.79%), Postives = 508/731 (69.49%), Query Frame = 3
Query:  204 DNEIKLKKTMKEPL------SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTS--EENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            D+E+ +  T++E L      S+TDDEV++REEEAI+LDGL+ +Q++E+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL++KIK DK  N+L + DTG+GMTR+ELVK LGTIAKSGT+EFL+K+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN FSV  DPRGNTLGRGT I L LK  AS+YLE + ++ LVR+YSQ+++FPIY+W+SKT   EE   +     +   + D+ A V +EE +      K    VWDWE +N  KPIW R   EV E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L++P+ AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS    ++T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD++E +K      + EF PL++++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       + +++        D  +++ A  L ETA + SGYL+ D   Y + +E +L+L+
Sbjct:   22 DDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESD-SNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPIYVWSSKTETVEEPLEEDEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREATEKEFEPLLNWMKD--KALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINP---RHPLIRDMLRRIKEDEDDKTVMDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLS 746          
BLAST of Endoplasmin vs. UniProt/SwissProt
Match: sp|Q66HD0|ENPL_RAT (Endoplasmin OS=Rattus norvegicus OX=10116 GN=Hsp90b1 PE=1 SV=2)

HSP 1 Score: 691.034 bits (1782), Expect = 0.000e+0
Identity = 364/740 (49.19%), Postives = 508/740 (68.65%), Query Frame = 3
Query:  204 DNEIKLKKTMKEPL------SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESA-----------TVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            D+E+ +  T++E L      S+TDDEV++REEEAI+LDGL+ +Q++E+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL++KIK D+  N+L + DTG+GMTR+ELVK LGTIAKSGT+EFL+K+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN FSV  DPRGNTLGRGT I L LK  AS+YLE + ++ LVR+YSQ+++FPIY+W+S         KT  V+   ++DE+A            V +EE +      K    VWDWE +N  KPIW R   EV E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L++P+ AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS    ++T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD++E SK      + EF PL++++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       + +++        D  +++ A  L ETA + SGYL+ D   Y + +E +L+L+
Sbjct:   22 DDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDREKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESD-SNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPIYVWSS---------KTETVEEPLEEDETAQEEKEEADDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKSKESREATEKEFEPLLNWMKD--KALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINP---RHPLIRDMLRRVKEDEDDKTVMDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLS 746          
BLAST of Endoplasmin vs. UniProt/SwissProt
Match: sp|P08110|ENPL_CHICK (Endoplasmin OS=Gallus gallus OX=9031 GN=HSP90B1 PE=1 SV=1)

HSP 1 Score: 691.034 bits (1782), Expect = 0.000e+0
Identity = 369/733 (50.34%), Postives = 520/733 (70.94%), Query Frame = 3
Query:  186 LDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIE--KEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSK--TSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXR--SDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            +D+T+E++  K ++      S+TDDEV++REEEAI+LDGL+ +Q+KE+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL++KIK DK  NML + DTGIGMT++EL+K LGTIAKSGT+EFL+K+   ++ +++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN FSV  DPRGNTLGRGT I L LK  AS+YLE + ++ LV++YSQ+++FPIY+W+SK  T EE   ++  + + +  DD  A V +EE +      K    VWDWE +N  KPIW R   EV E+EY  F+KT  K  D P++ IHF AEGEV+FKS+L++P+ AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   +K+G+IED +NR RL KL++  SS   +NLT+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ F+++E SK      + EF PL++++K   +  K+ IE  VL+ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP+HP+I  +   +  + + +  SDL ++     L ETA + SGY++ D  +Y + +E +L+L+
Sbjct:   26 VDATVEEDLGKSREG-----SRTDDEVVQREEEAIQLDGLNASQIKEIREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNMLHVTDTGIGMTKEELIKNLGTIAKSGTSEFLNKMTEMQDDSQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESD-SNEFSVIDDPRGNTLGRGTTITLVLKEEASDYLELDTVKNLVKKYSQFINFPIYVWSSKTETVEEPVEEEEAKEEKEETDDNEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKTFSKEHDDPMAYIHFTAEGEVTFKSILFVPNSAPRGLFDEYGSKKSDFIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEEKYNDTFWKEFGTNVKLGVIEDHSNRTRLAKLLRFQSSHHESNLTSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFEESEKSKESREALEKEFEPLLNWMKD--KALKDKIEKAVLSQRLTQSPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRRVKENEDDKTVSDLAVV-----LFETATLRSGYMLPDTKEYGDRIERMLRLS 745          
BLAST of Endoplasmin vs. UniProt/SwissProt
Match: sp|P41148|ENPL_CANLF (Endoplasmin OS=Canis lupus familiaris OX=9615 GN=HSP90B1 PE=1 SV=1)

HSP 1 Score: 687.567 bits (1773), Expect = 0.000e+0
Identity = 368/740 (49.73%), Postives = 515/740 (69.59%), Query Frame = 3
Query:  183 TLDSTIEDNEIKLKKTMKEPL------SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSK--DDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXR--SDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            T  S   D+E+ +  T++E L      S+TDDEV++REEEAI+LDGL+ +Q++E+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL++KIK DK  N+L + DTG+GMTR+ELVK LGTIAKSGT+EFL+K+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN FSV  DPRGNTLGRGT I L LK  AS+YLE + ++ LV++YSQ+++FPIY+W+SKT       +  E   + K   D+ A V +EE +      K    VWDWE +N  KPIW R   EV ++EY  F+K+  K  D P++ IHF AEGEV+FKS+L++P+ AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS   +++T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD++E +K      + EF PL++++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP+HP+I  +   +    + +  SDL ++     L ETA + SGYL+ D   Y + +E +L+L+
Sbjct:   15 TFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESD-SNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEDSDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEDDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAIEKEFEPLLNWMKD--KALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRRVKEDEDDKTVSDLAVV-----LFETATLRSGYLLPDTKAYGDRIERMLRLS 746          
BLAST of Endoplasmin vs. TrEMBL
Match: A0A1W7RHL7 (Endoplasmin-like protein OS=Agkistrodon contortrix contortrix OX=8713 PE=3 SV=1)

HSP 1 Score: 700.279 bits (1806), Expect = 0.000e+0
Identity = 368/729 (50.48%), Postives = 508/729 (69.68%), Query Frame = 3
Query:  186 LDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTEN--TSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            +D T+ED+  K ++      S+TDDEV++REEE+I+LDGL+ +Q+K++R+K+E+F FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR +SLTD + L +  EL+IKIK DK  NML +IDTGIGMT+DEL+K LGTIAKSGT+EFL+KI + + EN  TS+ IGQFGVGFYS +LVAD V V SK+NND Q IWESD SN FSV +DPRGNTLGRGT + L LK  AS+YLE + ++ LV +YSQ+++FPIY+W+SKT       +  EVK   + D+ A V +EE +           VWDWE +N  KPIW R   EV E+EY  F+K+  K  D+P++ IHF AEGEV+FKS+L+IPS AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS   +N T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++  +  N+A+ G+ FD++E SK      + E+ PL+ ++K   +  K+ IE  VL+ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       + +++        D ++ + A  LLETA + SGYL+ D  +Y   +E +L+L+
Sbjct:   26 VDGTVEDDLGKSREG-----SRTDDEVVQREEESIQLDGLNASQIKQLREKSERFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLMSLTDETALSDNEELTIKIKCDKEKNMLHVIDTGIGMTKDELIKNLGTIAKSGTSEFLNKISEMQEENQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDSQQIWESD-SNEFSVIEDPRGNTLGRGTTVTLVLKEEASDYLELDTVKNLVTKYSQFINFPIYVWSSKTETVEEPIEDEEVKDKDETDDEAAVEEEEEEKKPKTKPVQKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKETDEPMTYIHFTAEGEVTFKSILFIPSTAPRGLFDEYGSKKSDFIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSNHESNTTSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDNKRFQNVAKEGVKFDESEKSKEAHEALEKEYEPLLTWMKD--KALKDKIEKAVLSQRLTQSPCALVASQYGWSGNMERIMKAQAYQTGKDIATNYYASQKKIFEINP---KHPLIKDMLRRVQENEDDQIVADLAVVLLETATLRSGYLLPDTKEYGERIERMLRLS 743          
BLAST of Endoplasmin vs. TrEMBL
Match: J3S4B1 (Endoplasmin OS=Crotalus adamanteus OX=8729 PE=2 SV=1)

HSP 1 Score: 699.893 bits (1805), Expect = 0.000e+0
Identity = 368/729 (50.48%), Postives = 508/729 (69.68%), Query Frame = 3
Query:  186 LDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTEN--TSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            +D T+ED+  K ++      S+TDDEV++REEE+I+LDGL+ +Q+K++R+K+E+F FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR +SLTD + L +  EL+IKIK DK  NML +IDTGIGMT+DEL+K LGTIAKSGT+EFL+KI + + EN  TS+ IGQFGVGFYS +LVAD V V SK+NND Q IWESD SN FSV +DPRGNTLGRGT + L LK  AS+YLE + ++ LV +YSQ+++FPIY+W+SKT       +  EVK   + D+ A V +EE +           VWDWE +N  KPIW R   EV E+EY  F+K+  K  D+P++ IHF AEGEV+FKS+L+IPS AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS   +N T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++  +  N+A+ G+ FD++E SK      + E+ PL+ ++K   +  K+ IE  VL+ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       + +++        D ++ + A  LLETA + SGYL+ D  +Y   +E +L+L+
Sbjct:   26 VDGTVEDDLGKSREG-----SRTDDEVVQREEESIQLDGLNASQIKQLREKSERFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLMSLTDETALSDNEELTIKIKCDKEKNMLHVIDTGIGMTKDELIKNLGTIAKSGTSEFLNKITEMQEENQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDSQQIWESD-SNEFSVIEDPRGNTLGRGTTVTLVLKEEASDYLELDTVKNLVTKYSQFINFPIYVWSSKTETVEEPLEDEEVKDKDETDDEAAVEEEEEEKKPKTKPVQKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKETDEPMTYIHFTAEGEVTFKSILFIPSTAPRGLFDEYGSKKSDFIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSNHESNTTSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDNKRFQNVAKEGVKFDESEKSKEAHEALEKEYEPLLTWMKD--KALKDKIEKAVLSQRLTQSPCALVASQYGWSGNMERIMKAQAYQTGKDIATNYYASQKKIFEINP---KHPLIKDMLRRVQENEDDQIVADLAVVLLETATLRSGYLLPDTKEYGERIERMLRLS 743          
BLAST of Endoplasmin vs. TrEMBL
Match: T1E5V1 (Endoplasmin-like protein OS=Crotalus horridus OX=35024 PE=2 SV=1)

HSP 1 Score: 699.123 bits (1803), Expect = 0.000e+0
Identity = 367/729 (50.34%), Postives = 507/729 (69.55%), Query Frame = 3
Query:  186 LDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTEN--TSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            +D T+ED+  K ++      S+TDDEV++REEE+I+LDGL+ +Q+K++R+K+E+F FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR +SLTD + L +  EL+IKIK DK  NML +IDTGIGMT+DEL+K LGTIAKSGT+EFL+KI + + EN  TS+ IGQFGVGFYS +LVAD V V SK+NND Q IWESD SN FSV +DPRGNTLGRGT + L LK  AS+YLE + ++ LV +YSQ+++FPIY+W+SKT       +  EVK   + D+ A V +EE +           VWDWE +N  KPIW R   EV E+EY  F+K+  K  D+P++ IHF AEGEV+FKS+L+IPS AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS   +N T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++  +  N+A+ G+ FD++E SK      + E+ PL+ ++K   +  K+ IE  VL+ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       + +++        D ++ + A  L ETA + SGYL+ D  +Y   +E +L+L+
Sbjct:   26 VDGTVEDDLGKSREG-----SRTDDEVVQREEESIQLDGLNASQIKQLREKSERFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLMSLTDETALSDNEELTIKIKCDKEKNMLHVIDTGIGMTKDELIKNLGTIAKSGTSEFLNKITEMQEENQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDSQQIWESD-SNEFSVIEDPRGNTLGRGTTVTLVLKEEASDYLELDTVKNLVTKYSQFINFPIYVWSSKTETVEEPLEDEEVKDKDETDDEAAVEEEEEEKKPKTKPVQKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKETDEPMTYIHFTAEGEVTFKSILFIPSTAPRGLFDEYGSKKSDFIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSNHESNTTSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDNKRFQNVAKEGVKFDESEKSKEAHEALEKEYEPLLTWMKD--KALKDKIEKAVLSQRLTQSPCALVASQYGWSGNMERIMKAQAYQTGKDIATNYYASQKKIFEINP---KHPLIKDMLRRVQENEDDQIVADLAVVLFETATLRSGYLLPDTKEYGERIERMLRLS 743          
BLAST of Endoplasmin vs. TrEMBL
Match: A0A452E1G9 (Heat shock protein 90 beta family member 1 OS=Capra hircus OX=9925 GN=HSP90B1 PE=3 SV=1)

HSP 1 Score: 699.123 bits (1803), Expect = 0.000e+0
Identity = 366/738 (49.59%), Postives = 513/738 (69.51%), Query Frame = 3
Query:  183 TLDSTIEDNEIKLKKTMKEPL------SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTS--EENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            T  S   D+E+ +  T++E L      S+TDDEV++REEEAI+LDGL+ +Q++E+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL++KIK DK  N+L + DTG+GMTR+ELVK LGTIAKSGT+EFL+K+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN FSV  DPRGNTLGRGT I L LK  AS+YLE + ++ LV++YSQ+++FPIY+W+SKT   EE + ++    +   + D+ A V +EE +      K    VWDWE +N  KPIW R   EV E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L++P+ AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS   +++T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD++E SK      + EF PL++++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       + +++        D  +++ A  L ETA + SGYL+ D   Y + +E +L+L+
Sbjct:   15 TFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDETALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESD-SNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPAEEEEAAKEDKEESDDEAAVEEEEDEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDMTSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKSKESREAVEKEFEPLLNWMKD--KALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINP---RHPLIRDMLRRVKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLS 746          
BLAST of Endoplasmin vs. TrEMBL
Match: A0A452E1J7 (Heat shock protein 90 beta family member 1 OS=Capra hircus OX=9925 GN=HSP90B1 PE=3 SV=1)

HSP 1 Score: 699.123 bits (1803), Expect = 0.000e+0
Identity = 366/738 (49.59%), Postives = 513/738 (69.51%), Query Frame = 3
Query:  183 TLDSTIEDNEIKLKKTMKEPL------SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI--EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTS--EENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            T  S   D+E+ +  T++E L      S+TDDEV++REEEAI+LDGL+ +Q++E+R+K+EKF FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR ISLTD + L    EL++KIK DK  N+L + DTG+GMTR+ELVK LGTIAKSGT+EFL+K+   +E  ++TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN FSV  DPRGNTLGRGT I L LK  AS+YLE + ++ LV++YSQ+++FPIY+W+SKT   EE + ++    +   + D+ A V +EE +      K    VWDWE +N  KPIW R   EV E+EY  F+K+  K  D P++ IHF AEGEV+FKS+L++P+ AP  LF+     K   I+LYVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E++   FWKEF   IK+G+IED +NR RL KL++  SS   +++T+  +YV RMK +Q++IY++   + ++A++SPF+E+ LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD++E SK      + EF PL++++K   +  K+ IE  V++ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP       + +++        D  +++ A  L ETA + SGYL+ D   Y + +E +L+L+
Sbjct:   15 TFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDETALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESD-SNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPAEEEEAAKEDKEESDDEAAVEEEEDEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPSDMTSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKSKESREAVEKEFEPLLNWMKD--KALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINP---RHPLIRDMLRRVKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLS 746          
BLAST of Endoplasmin vs. Ensembl Cavefish
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 692.189 bits (1785), Expect = 0.000e+0
Identity = 374/731 (51.16%), Postives = 519/731 (71.00%), Query Frame = 3
Query:  186 LDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTE--NTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXR--SDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            +D T+ED+  K +       S+TDDEV++REEEAI+LDGL+ AQ+KE+R+K+EK  FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR +SLT+   L    EL++KIKADK  NML I DTGIGMT++ELVK LGTIAKSGT+EFL+K+ + ++E  +TS+ IGQFGVGFYS +LVADSV V SK+NND Q+IWESD SN FSV +DPRG+TLGRGT I L LK  AS+YLE E ++ LVR+YSQ+++FPIY+W+    EE +     E + ++ +DE+    +EE K      K    VWDWE +N  KPIW R   EV E+EY  F+KT  +  ++P+S IHF AEGEV+FKS+L++P+ AP  LF+     K+  I+L+VRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  EQ+  KFWKEF   IK+G+IED +NR RL KL++  +S S   L++  +YV RMK +Q++IY++   + ++A++SPF+EK LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ FD++E +K +    + EF PL  ++K +    K+ IE  VL+ RL ++P  +V    GW+GNMER+ ++Q+ +  +      +   KK LEINPKHP+I ++   + ++A  +  SDL ++     L ETA + SGY ++D   Y   +E +L+L+
Sbjct:   27 VDGTVEDDLGKSRDG-----SRTDDEVVQREEEAIQLDGLNAAQIKEIREKSEKHVFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLLSLTNDDALAGNEELTVKIKADKEKNMLHITDTGIGMTKEELVKNLGTIAKSGTSEFLNKMTEMQSEGQSTSELIGQFGVGFYSAFLVADSVIVTSKHNNDTQHIWESD-SNEFSVIEDPRGDTLGRGTTITLVLKEEASDYLELETIKNLVRKYSQFINFPIYVWSRPIDEEQA---EPEAEKETTEDEAEVEEEEEDKDKPKTKKVEKTVWDWELMNDIKPIWQRHAKEVEEDEYKAFYKTFSRDTEEPMSHIHFTAEGEVTFKSILFVPASAPRGLFDEYGSKKNDFIKLFVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEEQYNDKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQTSHSETVLSSLEQYVERMKEKQDKIYFMAGTSRKEAESSPFVEKLLKKGYEVVYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKAKEKREALEKEFEPLTTWMKDN--ALKDKIEKAVLSQRLTNSPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTLEINPKHPLIKEMLKRVQDNAEDQTASDLAVV-----LFETATLRSGYQLADTKAYGERIERMLRLS 741          
BLAST of Endoplasmin vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 504.212 bits (1297), Expect = 7.133e-167
Identity = 278/699 (39.77%), Postives = 433/699 (61.95%), Query Frame = 3
Query:  327 MRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSK------------------TSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            M +  E F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPS L +  +L I++  D  N  L IIDTGIGMT+ +L+  LGTIAKSGT  F+  ++          IGQFGVGFYS YLVA+ VTVI+K+N+D+QY+WES +  +F+V  D  G ++GRGT+++L LK   SEY E + ++ +V+++SQ++ +PI L+  K                   +E+    K  +V +D  +D                 K      D + +N  KPIWTR P +++ EEY EF+K+L    +  L+  HF+ EG++ F++LL++P +A  +LFE + K ++I+LYVRRVFI D   +++P YL+F+ G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K L++  ++  ++  + K +++F   IK+G+ ED  NR +L++L++ ++S S   + +  +YVSRMK  Q+ IYYI  E  +Q  NS F+E+  K   EV++  + +DE+ +  +++Y+G  L ++ + G+   + E  K + +  K +F  L   +K DI   K  IE + +++RLV++P  +V    GWT NMER+ +SQ+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   +AN +  ++KL 
Sbjct:   10 MEEDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLESCKDLKIELIPDLKNRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQ---AGADISMIGQFGVGFYSAYLVAERVTVITKHNDDEQYVWESAAGGSFTVKPD-NGESIGRGTKVILHLKEDQSEYTEEKRIKEVVKKHSQFIGYPITLFVEKQREKEVDLEEGEKEEEVPAAEDKDKPKIEDVGSDEDEDSKGNKN-------KRKKKVKEKYIDAQELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELMPEYLNFMKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTEISEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSNSGDEMVSLKDYVSRMKDSQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLLSVTKEGLELPEDEEEKKKQDELKTKFENLCKIMK-DILDKK--IEKVTVSNRLVASPCCIVTSTYGWTANMERIMKSQALRDNST---MGYMTAKKHLEINPLHPIVETLREKAEADKNDKAVKDLVIL-----LFETALLSSGFTLEDPQTHANRIYRMIKLG 686          
BLAST of Endoplasmin vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 504.212 bits (1297), Expect = 7.133e-167
Identity = 278/699 (39.77%), Postives = 433/699 (61.95%), Query Frame = 3
Query:  327 MRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSK------------------TSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            M +  E F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPS L +  +L I++  D  N  L IIDTGIGMT+ +L+  LGTIAKSGT  F+  ++          IGQFGVGFYS YLVA+ VTVI+K+N+D+QY+WES +  +F+V  D  G ++GRGT+++L LK   SEY E + ++ +V+++SQ++ +PI L+  K                   +E+    K  +V +D  +D                 K      D + +N  KPIWTR P +++ EEY EF+K+L    +  L+  HF+ EG++ F++LL++P +A  +LFE + K ++I+LYVRRVFI D   +++P YL+F+ G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K L++  ++  ++  + K +++F   IK+G+ ED  NR +L++L++ ++S S   + +  +YVSRMK  Q+ IYYI  E  +Q  NS F+E+  K   EV++  + +DE+ +  +++Y+G  L ++ + G+   + E  K + +  K +F  L   +K DI   K  IE + +++RLV++P  +V    GWT NMER+ +SQ+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   +AN +  ++KL 
Sbjct:   10 MEEDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLESCKDLKIELIPDLKNRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQ---AGADISMIGQFGVGFYSAYLVAERVTVITKHNDDEQYVWESAAGGSFTVKPD-NGESIGRGTKVILHLKEDQSEYTEEKRIKEVVKKHSQFIGYPITLFVEKQREKEVDLEEGEKEEEVPAAEDKDKPKIEDVGSDEDEDSKGNKN-------KRKKKVKEKYIDAQELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELMPEYLNFMKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTEISEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSNSGDEMVSLKDYVSRMKDSQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLLSVTKEGLELPEDEEEKKKQDELKTKFENLCKIMK-DILDKK--IEKVTVSNRLVASPCCIVTSTYGWTANMERIMKSQALRDNST---MGYMTAKKHLEINPLHPIVETLREKAEADKNDKAVKDLVIL-----LFETALLSSGFTLEDPQTHANRIYRMIKLG 686          
BLAST of Endoplasmin vs. Ensembl Cavefish
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:103047517])

HSP 1 Score: 295.819 bits (756), Expect = 1.202e-87
Identity = 163/419 (38.90%), Postives = 272/419 (64.92%), Query Frame = 3
Query: 1113 ERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            E +N  KPIWTR P +++ EEY EF+K+L    +  L+  HF+ EG++ F++LL+IP +AP +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K +V+K L++  +L  ++  + KF++ F   IK+G+ ED  NR +L++L++ HSS+S   +T+ +EY+SRMK  Q+ IYYI  E+ +Q  NS F+E+  K  +EVL+ T+ +DE+ +  +++++G  L ++ + G+   + E  K ++ + K +F  L   +K  ++     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   ++N +  ++KL 
Sbjct:  280 EELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAIKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYESFSKNIKLGIHEDSQNRKKLSELLRYHSSQSGDEMTSLSEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKMEDDKAKFENLCKLMKEILDKK---VEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVIL-----LFETALLSSGFSLDDPQTHSNRIYRMIKLG 687          
BLAST of Endoplasmin vs. Ensembl Cavefish
Match: trap1 (TNF receptor associated protein 1 [Source:NCBI gene;Acc:103028524])

HSP 1 Score: 293.508 bits (750), Expect = 1.673e-86
Identity = 196/629 (31.16%), Postives = 331/629 (52.62%), Query Frame = 3
Query:  345 KFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDD--QYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANL-FEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLK----VIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLI---EDDTNRNRLTKLIQMHSS-KSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSK--------SRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEIN 2174
            K +FQAE  +++ ++  SLY+ KE+F+RELISN SDAL+K+R   +T     G    L + ++ D    +L I DTGIGM ++ELV  LGTIA+SG+  FL  ++ + +E ++  IGQFGVGFYS ++VAD V V S++       Y W SD S  F + +    + + +GT+IVL LK    E+   + ++ ++ +YS ++SF IYL                                                +  R+N+ + +W   P E+SE ++ EF++ + ++ DKP   +H+ A+  ++ +S+ Y+P   P+     RE+  SS+ LY ++V I  K  DI+P++L F+ G+VDS+D+PLN+SRE LQ+  L++    V+Q++++R +LD  KK + E++ +F++++   ++ G+I   E D   + + KL++  SS       T+  EY SRMK+    +YY+   N   A+ SP+ E   + D EVLF  +  DE  L  + +++  KL + A   I  D  +  K         RL   + E   L+ +++  +  G++ + NI +T RL + P M+   + G   +  R  +      E + ++Q        LEIN
Sbjct:  147 KHEFQAETKKLLDIVARSLYSEKEVFIRELISNGSDALEKLRHKIITGG---GQDAPLELHLQTDAAKGILIIQDTGIGMNQEELVNNLGTIARSGSKAFLDTLQSQ-SETSNSIIGQFGVGFYSAFMVADKVDVYSQSAESGVPGYKWSSDGSGIFEIAE---ASGVRQGTKIVLHLKEECREFSSEDRVKEVINKYSNFVSFSIYL------------------------------------------------NGRRLNTLQALWMNDPKEISEWQHEEFYRYVAQAYDKPRYTLHYRADAPLNIRSIFYVPETKPSMFDVSREL-GSSVALYSKKVLIQTKATDILPKWLRFLRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRIIRFLLDQSKK-EPEKYDRFFEDYGLFVREGIITTAEQDVKED-IAKLLRFESSILPPGKQTSLLEYTSRMKAGTRNVYYLCAPNRHLAECSPYFEAMKQKDIEVLFCFEQFDELTLLHLREFDKKKLIS-AETDIVVDHYKEEKFQDSRPESERLTEPQAE--GLMAWMRNSL--GQK-VTNIKVTPRLDTHPAMITVLEMGAARHFLRTQQLARNVDERAQILQ------PTLEIN 705          
BLAST of Endoplasmin vs. Ensembl Sea Lamprey
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 565.459 bits (1456), Expect = 0.000e+0
Identity = 335/719 (46.59%), Postives = 458/719 (63.70%), Query Frame = 3
Query:  246 SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTE--NTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKAD---SKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHAL-----HLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            S+TDDEV++REEEAI LDGL+ AQ+KE+R+KAEK  FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR +SLTD   L    EL+IKIKADK  N+L I                          FLS+ ++  TE  +TS+ IGQFGVGFYS +LVAD + V SK+NND Q+IWESDSS  F+VT+DPRGNTL RGT I L LK  A++YLE E ++ LV++YSQ+++FPIY+W+SKT       +  E +A    + D +     +EE +      K    +WDWE +N  KPIW R   EV ++EY  F+K+  K  D+PL+ IHF AEGEV+F+S+L++P+ AP  +F+     K   I++YVRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  E +  KFWKEF   IK+G+IED +NR RL KL++  SS     LT+  EYV RMK +Q++IY+I   N ++ ++SPF+E+ LK  YEVLF T+ +DE+ +       M+ Y    ++  +R G          +R   ++    PL+             IE   ++ RL+ +P  +V    GW+GNMER+ ++Q+ +  +      +   KK  EINP+HP+I +L   +       +  DL L+     L ETA + SGYL+ D   +++ +E +L+++
Sbjct:   44 SRTDDEVVQREEEAITLDGLNAAQIKELREKAEKHVFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLMSLTDGKALDATDELTIKIKADKEKNLLHI--------------------------FLSRAQELATEGQSTSELIGQFGVGFYSAFLVADRIVVTSKHNNDTQHIWESDSSE-FTVTEDPRGNTLARGTTITLVLKEEAADYLELETIKNLVKKYSQFINFPIYVWSSKTETVEEPIEEEEEEAKEEKADDSDDDVEVEEEDEKKPKTKKVEKTIWDWELMNDIKPIWQRVTKEVEDDEYKAFYKSFSKDSDEPLTWIHFTAEGEVTFRSILFVPTSAPRGMFDEYGTKKTDFIKMYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIKKKLVRKTLDMIKKIADESYQEKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSYGTDKLTSLEEYVERMKEKQDKIYFIAGANRKEVESSPFVERLLKKGYEVLFLTEAVDEYCIQSDLGQFMDLYASILITAWSRLG---PSLRVYAARFAVQRG--FPLL---------CTRQIEKATVSQRLLGSPCALVASQYGWSGNMERIMKAQAYQTGKDAASNFYGSQKKTFEINPRHPLIKELLTRVQASEEDATAKDLALV-----LFETATLRSGYLLQDTRSFSDRIERMLRVS 716          
BLAST of Endoplasmin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003399.1 (pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 gene:ENSPMAG00000002912.1 transcript:ENSPMAT00000003399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 443.351 bits (1139), Expect = 1.828e-144
Identity = 266/701 (37.95%), Postives = 425/701 (60.63%), Query Frame = 3
Query:  327 MRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN---------SLKKTNEVKADSKDDESATV----TDEEXXXXXXXXXXXXXXW-----DWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKS--EQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            M ++ E F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPS + +  EL I    D I N                        ++  T F+     E  +  +D   IGQFGVGFYS YL+A+ V+V++K+N+D+QY+WES +  +F+V  D  G ++GRGT+IVL LK   SEYLE + ++ +V+++SQ++ +PI L+  K  ++            +K  E K    DD+   +    +D+E   +    KK          D E +N  KP+WTR P ++S+EEY EF+K+L    +  L+  HF+ EG++ F++LL++P +AP +LFE + K ++I+LYVRRVFI D   D+IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K +V+K +++   L    E + KF+++F   +K+G+ ED  NR RL+++++ H+S +  ++ +  EYVSRMK  Q+ IYYI  E+ EQ  NS F+E+  K   EV++ T+ +DE+ +  +++++G  L ++ + G+   + E  K +    K ++  L   +K  ++     +E + +++RLV++P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP+HPI+  L        N +S  DL+++     L ETA++SSG+ + D   ++N +  ++KL 
Sbjct:   10 MDEETETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKMDSGKELKI----DVIPN------------------------RNERTAFM-----EALQAGADISMIGQFGVGFYSAYLIAERVSVVTKHNDDEQYLWESSAGGSFTVRLD-NGESIGRGTKIVLHLKEDQSEYLEEKRIKDIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEEKEEKKEEEKEAETDDDKPKIEDVGSDDEADKEGDKDKKKKKKIKEKYVDKEELNKTKPLWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEDLIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCMELFTGLAEDKENYKKFYEQFSKNMKLGIHEDSQNRKRLSEMLRYHTSVTGEDVCSLKEYVSRMKENQKHIYYITGESKEQVSNSAFVERVRKRGLEVVYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEDEKKKQEEAKAKYENLCKVVKEILDKK---VEKVTVSNRLVASPCCIVTSTYGWTANMERIMKAQALRDSST---MGYMAAKKHLEINPEHPIVETLRQKAEADKNDKSVKDLIIL-----LFETALLSSGFSLDDPQTHSNRIYRMIKLG 665          
BLAST of Endoplasmin vs. Ensembl Sea Lamprey
Match: hsp90ab1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 187.963 bits (476), Expect = 7.834e-54
Identity = 115/320 (35.94%), Postives = 178/320 (55.62%), Query Frame = 3
Query:  444 ASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSK--------TSEENSLKKTNEVKADSKDDESATV----TDEEXXXXXXXXXXXXXXW------DWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVR 1349
            ++ ALDKIR+ SLTDPS L    EL I I  +KI+  L  +         E ++    I+                      IGQFGVGFYS YLVA+ VTV++K+N+D+QY+WES +  +F+V  D  G  LGRGT+IVL +K   +EYLE  +++ +V+++SQ++ +PI L+  K          E+      ++ K +  DD++  +    +DEE        KK           D E +N  KP+WTR P +++ EEY EF+K+L    +  L+  HF+ EG++ F++LL++P +A  +LFE + K ++I+LYVR
Sbjct:    1 SAQALDKIRYESLTDPSKLDTGKELKIDIIPNKIDRTLTFM---------EALQAGADIS---------------------MIGQFGVGFYSAYLVAERVTVVTKHNDDEQYVWESSAGGSFTVRPDNDGEPLGRGTKIVLHIKEDQTEYLEERSIKDIVKKHSQFIGYPITLYVEKERNKEVSDDEEDKEEAAPDKPKEERSDDDTPNIEDVGSDEEEDKAKDSDKKKKKKKIKEKYTDKEELNKTKPLWTRNPDDITAEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKKNNIKLYVR 290          
BLAST of Endoplasmin vs. Ensembl Yeast
Match: HSC82 (Cytoplasmic chaperone of the Hsp90 family; plays a role in determining prion variants; redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock; contains two acid-rich unstructured regions that promote the solubility of chaperone-substrate complexes; HSC82 has a paralog, HSP82, that arose from the whole genome duplication [Source:SGD;Acc:S000004798])

HSP 1 Score: 479.945 bits (1234), Expect = 1.228e-158
Identity = 275/681 (40.38%), Postives = 431/681 (63.29%), Query Frame = 3
Query:  339 AEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLK--SEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
             E F+FQAE+ ++M LIIN++Y+NKEIFLRELISNASDALDKIR+ +L+DP  L   P+L I+I       +L I D+GIGMT+ EL+  LGTIAKSGT  F+  +           IGQFGVGFYS++LVAD V VISKNN D+QYIWES++  +F+VT D     +GRGT + L LK    EYLE + ++ +++++S+++++PI L  +K  E+         K   +   D K  +   V +EE +      K    V + E +N  KP+WTR P+++++EEYN F+K++    + PL   HF+ EG++ F+++L+IP +AP +LFE + K ++I+LYVRRVFITD+  D+IP +LSF+ G+VDS+DLPLN+SRE LQQ K++KVI+K +V+K+++   ++   SEQF KF+  F   IK+G+ ED  NR  L KL++ +S+KS+  LT+  +YV+RM   Q+ IYYI  E+L+  + SPF++     ++EVLF TD +DE+A   ++++EG  L ++ +     ++T+  K+    +  E+ PL   +K DI   +  +E +V++ +L+ AP  +     GW+ NMER+ ++Q+ +         ++  KK  EI+PK PII +L   ++       D  + +    L ETA+++SG+ + + T +A+ +  ++ L 
Sbjct:    3 GETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPKQLETEPDLFIRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEAL---SAGADVSMIGQFGVGFYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTLDEVNERIGRGTVLRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLLVTKEVEKEVPIPEEEKKDEEKKDEDDKKPKLEEVDEEEEEKKPKTKKVKEEVQELEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFDKFYSAFAKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITK-DFELEETDEEKAEREKEIKEYEPLTKALK-DILGDQ--VEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSM---SSYMSSKKTFEISPKSPIIKELKKRVDEGGA--QDKTVKDLTNLLFETALLTSGFSLEEPTSFASRINRLISLG 671          
BLAST of Endoplasmin vs. Ensembl Yeast
Match: HSP82 (Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication [Source:SGD;Acc:S000006161])

HSP 1 Score: 476.478 bits (1225), Expect = 2.601e-157
Identity = 275/685 (40.15%), Postives = 432/685 (63.07%), Query Frame = 3
Query:  339 AEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN----------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLK--SEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            +E F+FQAE+ ++M LIIN++Y+NKEIFLRELISNASDALDKIR+ SL+DP  L   P+L I+I       +L I D+GIGMT+ EL+  LGTIAKSGT  F+  +           IGQFGVGFYS++LVAD V VISK+N+D+QYIWES++  +F+VT D     +GRGT + L LK    EYLE + ++ +++++S+++++PI L  +K  E+             KK  E K +          DEE +      K    V + E +N  KP+WTR P+++++EEYN F+K++    + PL   HF+ EG++ F+++L+IP +AP +LFE + K ++I+LYVRRVFITD+  D+IP +LSF+ G+VDS+DLPLN+SRE LQQ K++KVI+K +V+K+++   ++   SEQF KF+  F   IK+G+ ED  NR  L KL++ +S+KS+  LT+  +YV+RM   Q+ IYYI  E+L+  + SPF++     ++EVLF TD +DE+A   ++++EG  L ++ +     ++T+  K+    +  E+ PL   +K   E   + +E +V++ +L+ AP  +     GW+ NMER+ ++Q+ +         ++  KK  EI+PK PII +L   ++       D  + +  + L ETA+++SG+ + + T +A+ +  ++ L 
Sbjct:    3 SETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEAL---SAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKDEDDKKPKLEEVDEEEEKKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITK-DFELEETDEEKAEREKEIKEYEPLTKALK---EILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSM---SSYMSSKKTFEISPKSPIIKELKKRVDEGGA--QDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLG 675          
BLAST of Endoplasmin vs. Ensembl Nematostella
Match: EDO45344 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT97])

HSP 1 Score: 339.732 bits (870), Expect = 3.288e-103
Identity = 168/247 (68.02%), Postives = 206/247 (83.40%), Query Frame = 3
Query:  246 SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI-EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSE 983
            S+TDDE ++REEEAIKLDGL+ AQ+KE+R KAEK +FQAEV+RMMKLIINSLY NKEIFLRELISN+SDALDKIR +SLTD +   +  ELSIKIKADK NN+L + DTGIGMT++EL+K LGTIAKSGT+EF  KI E   +++ SD IGQFGVGFYS +LVAD V V SKNN+D QYIWESD+S +FS+++DPRG TL RGT I L LK  A +YLE E ++ LV++YSQ+++FPI+LWTSKT+E
Sbjct:   45 SRTDDEAVQREEEAIKLDGLNVAQMKELRDKAEKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNSSDALDKIRLMSLTDKTAFDSGDELSIKIKADKENNILHVTDTGIGMTKEELIKNLGTIAKSGTSEFFQKIQEAASSDSASDLIGQFGVGFYSSFLVADRVIVTSKNNDDKQYIWESDAS-SFSISEDPRGPTLKRGTTISLHLKEEARDYLEPETIKDLVKKYSQFINFPIFLWTSKTTE 290          
BLAST of Endoplasmin vs. Ensembl Nematostella
Match: EDO45666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS03])

HSP 1 Score: 305.834 bits (782), Expect = 9.639e-93
Identity = 197/625 (31.52%), Postives = 327/625 (52.32%), Query Frame = 3
Query:  351 QFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKN--NNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLK----VIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLI--EDDTNRNRLTKLIQMHSS-KSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRP-----LIDFIKTDIEPGKEFIENIVLTDRLVSA--PMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINP 2177
            +FQAE  +++ ++  SLY+ KE+F+RE+ISNASDAL+K+R   LT   V      L I I+ D+      I D G+GMT +EL+  LG IAKSG+  F+ K++ E   +  + IGQFGVGFYS ++VAD V V +K+   N   Y W SD S ++   +    N + RGT++VL LK     +     +  +V++YS ++ FPIYL              N V                                   IN+ +P+WT +P ++S+E+++EF++ L K  DKP   +H+  +  ++ +S+ Y P   P  +F  +  +S I LY RRV I  K   ++PR+L FI G+VDS+D+PLN+SRE LQ   L+K    V+  +LV+ + +  +K +  ++ KF+K+    I+ G++  ED+  +  + KL+   SS +    LT    YVSRMK  Q+++YY+   + + A+ SP+ E   + D EVLF  +  D+  LH + KYE   + +      F  + E +K +   +  +  P     L  ++ + + P +  +  + ++ RL +   P M+   D     +  +L +++  K+ E+    ++  ++  LEINP
Sbjct:   14 EFQAETKQLLDIVAKSLYSEKEVFIREVISNASDALEKVRHFFLTGKDVSETETSLEIMIETDQEAGTFTIQDNGVGMTEEELMDHLGVIAKSGSKVFMEKLKNEARSSHENIIGQFGVGFYSTFMVADKVDVYTKSYQPNSQGYFWTSDGSGSYEYAE---ANGVARGTKLVLHLKEDCKRFAMKTAVEDIVQRYSNFVGFPIYL--------------NGVC----------------------------------INTIQPLWTLEPRDISKEQHDEFYQFLSKGYDKPRYYLHYKTDAPLNIRSIFYFPETLP-QMFNMQQMESGISLYSRRVLIQAKAEKVLPRWLRFIRGVVDSEDIPLNLSRELLQDSALIKKLSNVLSARLVKFLQEQARKDRV-KYEKFFKDCGIFIREGVVTTEDEEQKEEIAKLLLFESSNEKPGTLTNLPAYVSRMKPTQKKVYYLCAPSRDLAETSPYYETLKQNDVEVLFSYNEQDDVVLHYLRKYENKAVISAEN---FLSEAEDTKPKNEPEVEDVTPEEGKDLAGWMSSILGPTR--VVGVKVSKRLANTNHPAMITVPDMVAAKHWLKLIKTEHNKEVEN---MKYQIIQPTLEINP 577          
BLAST of Endoplasmin vs. Ensembl Nematostella
Match: HSP90 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ66])

HSP 1 Score: 281.567 bits (719), Expect = 6.962e-83
Identity = 161/421 (38.24%), Postives = 264/421 (62.71%), Query Frame = 3
Query: 1107 DWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            + E +N  KPIW R   E++ EEY EF+K+L    ++ L+  HF+ EG++ F++LL++P +AP +LFE   K ++I+LYVRRVFI D   D+IP YL FI G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K +++  ++  +Q  + KF+++F   +K+G+ ED  NR +L  L++ HSS S   LT+  +YV+RMK  Q++IY+I  E+ +Q  +S F+E+     +EVL+  + +DE+A+  +++Y+G KL ++ + G+   + E  K     K  ++  L   IK DI   K  IE +V++ RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP H I+  L   +    N +S  DL+++ Y     ET++++SG+ + D   ++  +  ++ L 
Sbjct:  280 EMEELNKTKPIWMRNADEITTEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPKRAPFDLFESRKKRNNIKLYVRRVFIMDNCEDLIPEYLGFIKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCMELFNEIAEDQDNYKKFYEQFGKNLKLGIHEDSVNRAKLADLLRYHSSSSGDELTSLKDYVTRMKENQKDIYFITGESKDQVSHSAFVERVKSRGFEVLYMVEPIDEYAIQQLKEYDGKKLVSVTKEGLELPEDEDEKKAREEKVAKYEGLCKVIK-DILDKK--IEKVVVSSRLVSSPCCIVTSQFGWTANMERIMKAQALRDNST---MGYMAAKKHLEINPDHAIMDSLRKKVEADKNDKSLKDLVMLLY-----ETSLLTSGFTLEDPQVHSGRIYRMIGLG 689          
BLAST of Endoplasmin vs. Ensembl Medaka
Match: hsp90b1 (heat shock protein 90 beta family member 1 [Source:NCBI gene;Acc:101166123])

HSP 1 Score: 688.723 bits (1776), Expect = 0.000e+0
Identity = 375/737 (50.88%), Postives = 516/737 (70.01%), Query Frame = 3
Query:  201 EDNEIKLKKTMKEPL------SKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTE--NTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTS--EE---NSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER--EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFG-KFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXR--SDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            ED+E+ +  T++E L      S+TDDEV++REEEAI+LDGL+ AQ+KE+R+K+EK  FQAEV+RMMKLIINSLY NKEIFLRELISNASDALDKIR +SLT    L    EL+IKIK+DK  NML I DTGIGMT++EL+K LGTIAKSGT+EFL+K+ + ++E  +TS+ IGQFGVGFYS +LVAD V V SK+NND Q+IWESD SN FSV +DPRG+TLGRGT I L LK  AS++LE E ++ LVR+YSQ+++FPIY+W SKT   EE      +     K  S+D+      + E K      K    VWDWE +N  KPIW R   EV E+EY  F+KT  K  + PL+ IHF AEGEV+FKS+L++PS AP  LF+     K+  ++L+VRRVFITD   D++P+YL+F+ G+VDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDMIKK+  EQ+  KFWKEF   IK+G+IED +NR RL KL++  +S S   L +  +YV RMK +Q++IY++   + ++A++SPF+EK LK  YEV++ T+ +DE+ +  + +++G +  N+A+ G+ F+++E +K +    + EF PL+ ++K   +  K+ IE  VL+ RL  +P  +V    GW+GNMER+ ++Q+ +  +      +   KK LEINPKHP+I ++   +N+ A  +  SDL ++     L ETA + SGY ++D   Y + +E +L+L+
Sbjct:   22 EDDEVDVDATVEEELGKSRDGSRTDDEVVQREEEAIQLDGLNAAQIKELREKSEKHMFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLLSLTHEDALAANEELTIKIKSDKEKNMLHITDTGIGMTKEELIKNLGTIAKSGTSEFLNKMSEMQSEGQSTSELIGQFGVGFYSAFLVADKVIVSSKHNNDTQHIWESD-SNQFSVIEDPRGDTLGRGTTITLVLKEEASDFLELETIKNLVRKYSQFINFPIYVWASKTETVEEPIEEDAETEEPEKEASEDEVEVEEEEGEDKDKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKTFSKDSEDPLTHIHFTAEGEVTFKSILFVPSAAPRGLFDEYGSKKNDFVKLFVRRVFITDDFNDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEEQYNEKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQTSNSETGLASLEQYVERMKEKQDKIYFMAGTSRKEAESSPFVEKLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFEESEKAKEKREALEKEFEPLMTWLKD--KALKDKIEKAVLSQRLTDSPCALVASQYGWSGNMERIMKAQAYQTGKDISTSYYASQKKTLEINPKHPLIKQMLGRVNDDAEDQTASDLAVV-----LFETATLRSGYQLADTKAYGDRIERMLRLS 750          
BLAST of Endoplasmin vs. Ensembl Medaka
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:100125466])

HSP 1 Score: 496.893 bits (1278), Expect = 4.127e-164
Identity = 280/696 (40.23%), Postives = 437/696 (62.79%), Query Frame = 3
Query:  348 FQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN--------------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLK--SEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            F FQAE+ ++M LIIN+ Y+NKEIFLRELISNASDALDKIR+ SLTDPS L +  +L I I  +K +  L I+DTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ V VI+K+N+D+QY WES +  +F+V  D  G  +GRGT+I+L LK   +EY+E + ++ +V+++SQ++ +PI L+  K  ++                        K  +V +D ++D       ++   +           D E +N  KPIWTR P +++ EEY EF+K+L    +  L+  HF+ EG++ F++LL++P +AP +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K +V+K L++  +L    E + KF++ F   IK+G+ ED  NR +L++L++ HSS+S   +T+  EY+SRMK  Q+ IYYI  E+ +Q  NS F+E+  K  +EVL+ T+ +DE+ +  +++++G  L ++ + G+   + E  K ++ + K +F  L   +K  ++     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N ++  DL+++     L ETA++SSG+ + D   ++N +  ++KL 
Sbjct:   14 FAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNKADRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAERVVVITKHNDDEQYAWESSAGGSFTVKVD-SGEPIGRGTKIILHLKEDQTEYIEEKRVKEIVKKHSQFIGYPITLFVEKERDKEISDDEAEEEKEEKETKEEGEDKPKIEDVGSDDEEDAKDKGKKKKKIKEKYI--------DQEELNKTKPIWTRNPDDITSEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFGELAEDKENYKKFYEGFSKNIKLGIHEDSQNRKKLSELLRYHSSQSGDEMTSLTEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKNLVSVTKEGLELPEDEEEKKKMEDDKAKFENLCKLMKEILDKK---VEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMMAKKHLEINPDHPIMETLRQKAETDKNDKAVKDLVIL-----LFETALLSSGFSLDDPQTHSNRIYRMIKLG 684          
BLAST of Endoplasmin vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 496.893 bits (1278), Expect = 4.216e-164
Identity = 279/694 (40.20%), Postives = 432/694 (62.25%), Query Frame = 3
Query:  327 MRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN-------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            M ++ E F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPS L +  EL I+++ D     L I DTGIGMT+ +L+  LGTIAKSGT  F+  ++          IGQFGVGFYS YLVA+ VTVI+K+N+D+QYIWES +  +F+V  D  G  +GRGT+++L LK   +EY E + ++ +++++SQ++ +PI L+  KT E+                   N+ K   +D  S    D +   +    K      D + +N  KPIWTR P +++ EEY EF+K+L    +  L+  HF+ EG++ F++LL++P +A  +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K L++  +L  ++  + K +++F   IK+G+ ED  NR +L++L++ ++S S   + +  +YVSRMK  Q+ IYYI  E  +Q  NS F+E+  K   EV++  + +DE+ +  ++ ++G  L ++ + G+   + E  K +   KK +F  L   +K  +E     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N +S  DL+++     L ETA++SSG+ + D   +AN +  ++KL 
Sbjct:    9 MEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQ---AGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPD-NGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEVDLEEGEKVEEVEKESAENKDKPQIEDVGSDEDEDTKDGKNKRKKKVKEKYIDAQELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVSRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKK---VEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMAAKKHLEINPDHPIMETLRQKAEADKNDKSVKDLVIL-----LFETALLSSGFTLEDPQTHANRIYRMIKLG 687          
BLAST of Endoplasmin vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 496.508 bits (1277), Expect = 7.361e-164
Identity = 278/694 (40.06%), Postives = 432/694 (62.25%), Query Frame = 3
Query:  327 MRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN-------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            M ++ E F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPS L +  EL I+++ D     L I DTGIGMT+ +L+  LGTIAKSGT  F+  ++          IGQFGVGFYS YLVA+ VTVI+K+N+D+QYIWES +  +F+V  D  G  +GRGT+++L LK   +EY E + ++ +++++SQ++ +PI L+  KT E+                   N+ K   +D  S    D +   +    K      D + +N  KPIWTR P +++ EEY EF+K+L    +  L+  HF+ EG++ F++LL++P +A  +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K L++  +L  ++  + K +++F   IK+G+ ED  NR +L++L++ ++S S   + +  +YV+RMK  Q+ IYYI  E  +Q  NS F+E+  K   EV++  + +DE+ +  ++ ++G  L ++ + G+   + E  K +   KK +F  L   +K  +E     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N +S  DL+++     L ETA++SSG+ + D   +AN +  ++KL 
Sbjct:    9 MEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQ---AGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPD-NGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEVDLEEGEKVEEVEKESAENKDKPQIEDVGSDEDEDTKDGKNKRKKKVKEKYIDAQELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKK---VEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMAAKKHLEINPDHPIMETLRQKAEADKNDKSVKDLVIL-----LFETALLSSGFTLEDPQTHANRIYRMIKLG 687          
BLAST of Endoplasmin vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 496.123 bits (1276), Expect = 1.015e-163
Identity = 280/696 (40.23%), Postives = 434/696 (62.36%), Query Frame = 3
Query:  327 MRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEEN-------------SLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            M ++ E F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPS L +  EL I+++ D     L I DTGIGMT+ +L+  LGTIAKSGT  F+     E  +  +D   IGQFGVGFYS YLVA+ VTVI+K+N+D+QYIWES +  +F+V  D  G  +GRGT+++L LK   +EY E + ++ +++++SQ++ +PI L+  KT E+                   N+ K   +D  S    D +   +    K      D + +N  KPIWTR P +++ EEY EF+K+L    +  L+  HF+ EG++ F++LL++P +A  +LFE + K ++I+LYVRRVFI D   ++IP YL+FI G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K L++  +L  ++  + K +++F   IK+G+ ED  NR +L++L++ ++S S   + +  +YV+RMK  Q+ IYYI  E  +Q  NS F+E+  K   EV++  + +DE+ +  ++ ++G  L ++ + G+   + E  K +   KK +F  L   +K  +E     +E + +++RLVS+P  +V    GWT NMER+ ++Q+ +   +     ++  KK+LEINP HPI+  L        N +S  DL+++     L ETA++SSG+ + D   +AN +  ++KL 
Sbjct:    9 MEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFM-----EALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPD-NGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEVDLEEGEKVEEVEKESAENKDKPQIEDVGSDEDEDTKDGKNKRKKKVKEKYIDAQELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKK---VEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNST---MGYMAAKKHLEINPDHPIMETLRQKAEADKNDKSVKDLVIL-----LFETALLSSGFTLEDPQTHANRIYRMIKLG 687          
BLAST of Endoplasmin vs. Planmine SMEST
Match: SMESG000068132.1 (SMESG000068132.1)

HSP 1 Score: 1538.09 bits (3981), Expect = 0.000e+0
Identity = 832/832 (100.00%), Postives = 832/832 (100.00%), Query Frame = 3
Query:  117 HTDESDQESVFQATKESKITPETLDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLNYKDQGNLHXXXXXXXXXXXXXXXSFEYDEKLAHAVPRDANNYAXXXXXXXXXXXXXXXAAEPQNPQTNSGNINEKKMVEEIHDDL 2612
            HTDESDQESVFQATKESKITPETLDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEPKSDVSPPKKSSVVWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPKHPIIIKLNNLINNHANPRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLNYKDQGNLHDDANEEDDSNENKENSFEYDEKLAHAVPRDANNYASDESDDFDDVDSSSSAAEPQNPQTNSGNINEKKMVEEIHDDL
Sbjct:   22 HTDESDQESVFQATKESKITPETLDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEPKSDVSPPKKSSVVWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPKHPIIIKLNNLINNHANPRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLNYKDQGNLHDDANEEDDSNENKENSFEYDEKLAHAVPRDANNYASDESDDFDDVDSSSSAAEPQNPQTNSGNINEKKMVEEIHDDL 853          
BLAST of Endoplasmin vs. Planmine SMEST
Match: SMESG000041107.1 (SMESG000041107.1)

HSP 1 Score: 688.337 bits (1775), Expect = 0.000e+0
Identity = 385/734 (52.45%), Postives = 517/734 (70.44%), Query Frame = 3
Query:  162 ESKITPETLDSTIEDNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTEN-TSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTS--EENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFER-EIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILK 2351
            ES++ P++ +  I+++  K K+      SKTDDEV++REEEAI LDGL+ AQ+KE+R KAEKF FQAEVD+MMKLIINSLY NKEIFLRELISNASDALDKIRFISLTD + L  F +L IKIKADK    L I+DTG+GMT+ +L+  LGTIAKSGT++FL K+   K+ N  SD IGQFGVGFYS +LVAD VTVISK+N+D Q+IWESD+ N+FSV +DPRGNTL RGTEI+L LK  A EYLE+++L+ LV +YSQ+++FPIYLW+SKT   EE  ++  NE     K DE  TV   E K    P K    VWDWE +N  KPIWTRK +++ +EEYNEF+K+  K+ + PL+KIHF AEGEV+FKS+L++P+K P N ++  E    +I++YVRRVFITD   D++P+YLSFI+GIVDSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDM+KK+  E F KFWKEF   +K+G++ED +NR RL KL++  +S +    +T  +YVSRMK +QE IYYI   + +    SP +EK LK  +EV++  D +DE+ +  + ++EG K+ NL + G+ FD ++ +K +      EF PL+ ++K  +    E IE   +++RL ++P  VV    GWTGNMER+ ++Q+ +   +   +     KK LEINPKHP+I +L   +  +    +D    + A +L ETAI+ SGY +     +A+ +E IL+
Sbjct:   27 ESQVKPQSDEIKIDEDITKSKQG-----SKTDDEVVKREEEAINLDGLNVAQMKELRDKAEKFAFQAEVDKMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTDSTALDAFKDLHIKIKADKDGKSLHIVDTGVGMTKQDLITNLGTIAKSGTSDFLKKLSDSKSTNEMSDLIGQFGVGFYSSFLVADKVTVISKHNDDKQHIWESDA-NSFSVVEDPRGNTLLRGTEIILHLKEEAHEYLEADSLKNLVTKYSQFINFPIYLWSSKTETVEEKPIETKNE--DTEKKDEDVTVE--EEKEKEKPKKVDKTVWDWELVNKNKPIWTRKASDIKDEEYNEFYKSFGKTSENPLAKIHFTAEGEVTFKSILFVPAKPPYNYYQNPETHRDNIKMYVRRVFITDDFNDMMPKYLSFIVGIVDSDDLPLNVSRETLQQNKLLKVIKKKLVRKTLDMLKKMSEEDFDKFWKEFSTSLKLGVVEDVSNRTRLAKLLRFWTSHNDKKQSTLTDYVSRMKEKQEVIYYIAGHSKDDLIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSLTEFEGKKMQNLGKEGVKFDDSDKAKEQREITAKEFEPLLKWLKDSV--LNEQIEKAEISERLSTSPCAVVASTYGWTGNMERIMKAQAYQSASNSYNEYQSSQKKILEINPKHPLIKELKRQVEKNP---TDEKAKDIALTLYETAILRSGYSLPASGGFADRIEKILR 745          
BLAST of Endoplasmin vs. Planmine SMEST
Match: SMESG000054819.1 (SMESG000054819.1)

HSP 1 Score: 654.055 bits (1686), Expect = 0.000e+0
Identity = 371/743 (49.93%), Postives = 508/743 (68.37%), Query Frame = 3
Query:  153 ATKESKITPETLDSTIEDNEIKLKKTM---KEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKI-EKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNE--VKADSKDDESATVTDEEXXXXXXXXXXXXXXWDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRSDLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLNYK 2363
            +T ESKI  E       D+ +KLK+ +   KEP SKTDDEV++REEEAI +DGL+ +Q+KE+R+KAEK+ FQAEVDRMMKLIINSLY NKEIFLRELISNASDALDKIRFISLT+     +  +L IKIKADK    + I+DTG+GMT+ EL+K LGTIAKSGT++F+ K+ E + T   ++ IGQFGVGFYS +LVAD VTVISK++ D QYIWESD+S TFS+ +DPRGNTL RGTE++L LK    E+LE + LR L+ +YSQ+++FPIYLW S      S+K  +E    A SK DE A V +E  +            WDWE +N  KPIWTRK  E  +EEYNEF+K+  K  + PL+K HF AEGEV FK++LYIP K+       + K+ +I+LYV+RVFITD   DI+P+YLSF+ GI+DSDDLPLNVSRETLQQ KLLKVI+KKLVRK LDM KKL  + F +FWKE+   IK+G+IED +NRNRL KLI+  SS S  + T+ A+YVSRMK  Q++I++I   +L   + SP +E  LK  YEVL+  + +DE+    + ++EG K  N+A+ G   D ++         + E+ PLI+++K+     K++IE + +++RL ++P +++    GW+GNMER+ ++Q+ ++ E  +    +  KK LEIN +H +I  L    +N  +      L   A+ L +TA++ SGY++ +V  ++  V +I+K + K
Sbjct:   35 STDESKIKDEA------DSNLKLKENIAKSKEP-SKTDDEVVKREEEAISIDGLNVSQIKELREKAEKYTFQAEVDRMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTNQDRNFDNEDLYIKIKADKAAKTIHILDTGVGMTKTELIKNLGTIAKSGTSDFIQKLSEAKNTGELNELIGQFGVGFYSSFLVADKVTVISKSDADYQYIWESDAS-TFSIVRDPRGNTLERGTEVILHLKDEVLEFLEIDVLRNLIHKYSQFINFPIYLWKS------SVKNVDEDHESAVSKRDEDANVENENERKSTERTV-----WDWELVNKNKPIWTRKSGETPDEEYNEFYKSFSKDSENPLAKTHFTAEGEVQFKAILYIPKKSNVEFNSVDKKNDNIKLYVKRVFITDDFDDIMPKYLSFMKGIIDSDDLPLNVSRETLQQHKLLKVIKKKLVRKTLDMFKKLPEDIFKEFWKEYATNIKLGVIEDVSNRNRLAKLIRFWSSHSQESQTSLADYVSRMKPTQDKIFFIAGVSLSDVQLSPMVEILLKKQYEVLYLIEPIDEYTFQSLPEFEGKKFQNVAKEGFKLDDSDKKIEIKEKLEKEYEPLINWLKS--TELKDYIEKVEISERLTTSPCVLIASTYGWSGNMERIMKAQAYQKSEEVMQTYQVNQKKILEINTQHSLIRHLKYSFSNGQDMNETRKL---AKFLYDTALLRSGYIMDNVASFSKQVHEIIKTSMK 753          
BLAST of Endoplasmin vs. Planmine SMEST
Match: SMESG000071533.1 (SMESG000071533.1)

HSP 1 Score: 502.286 bits (1292), Expect = 1.799e-166
Identity = 281/692 (40.61%), Postives = 438/692 (63.29%), Query Frame = 3
Query:  339 AEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDW-------------ERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            AE F FQAE+ ++M LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPSVL +  +L IKI  DK    L IIDTGIGMT+ +L+  LGTIA+SGT  F+     E  +  +D   IGQFGVGFYS YLVAD V VISK+N+D+QY+WES +  +F++  D     +GRG++++L +K    EYL+ + ++ +++++SQ++ +PI L   K  ++       EV  D K+ ES    D+    D+   +                     E +N  KPIWTR P +VS+E+Y EF+K+L    +  L+  HF+ EG++ F++LL+ P +AP +LFE + K ++I+LYVRRVFI D   D+IP YL+F+ G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K L++ +++  ++  + KF+++F   IK+G+ ED  NRN++ + ++ +S+ S   +T+  +Y+SRMK  Q++IYYI  E+ +   +S F+E+  K  +EVL   D +DE+++  +++Y+G KL  + + G+   + E  K +   +K  F PL   +K DI   K  +E + +++RLVS+P  +V    GW+ NMER+ ++Q+ +   +     ++  KK+LEINP H I+  L   ++   N +S  DL+++     L ET+++SSG+ + D   + N +  ++KL 
Sbjct:    6 AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIIDTGIGMTKADLINNLGTIARSGTKAFM-----EALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYD-NSEPIGRGSKVILYMKEDQIEYLDEKKIKEIIKKHSQFIGYPIKLVLEKERDKEISDDEAEVD-DKKEKESEDTEDKPKIEDLDDEEDDDKKDKDKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEKKKFEEQKAAFEPLCKVMK-DILDKK--VEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSST---MGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVML-----LFETSLLSSGFSLEDPQVHGNRIHRMIKLG 679          
BLAST of Endoplasmin vs. Planmine SMEST
Match: SMESG000024822.1 (SMESG000024822.1)

HSP 1 Score: 494.967 bits (1273), Expect = 1.157e-163
Identity = 282/689 (40.93%), Postives = 441/689 (64.01%), Query Frame = 3
Query:  339 AEKFQFQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLGNFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSKIEKEKTENTSD--FIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSNTFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFPIYLWTSK-----TSEENSLKKTNEVKADSKDDESATVTDEEXXXXXXXXXXXXXXWDW-----ERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGEVSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSFIIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQ--FGKFWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKSQQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKYEGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFIENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKVKKNLEINPXXXXXXXXXXXXXXXXXXRS--DLLLINYAQSLLETAIISSGYLVSDVTKYANMVEDILKLN 2357
            +E F FQAE+ +++ LIIN+ Y+NKEIFLRELISN+SDALDKIR+ SLTDPSVL    EL IKI  DK    L IIDTGIGMT+ +L+  LGTIA+SGT  F+     E  +  +D   IGQFGVGFYS YLVAD V VISK N+D+QY+WES +  +F++  D     LGRG++I+L +K    EYLE   ++ +++++SQ++ +PI L   K      S++ +  +T + +++  +D+      ++ + D    KK            E +N  KPIWTR P +VS+E+Y EF+K+L    +  L+  HF+ EG++ F++LL+ P +AP +LFE + K ++I+LYVRRVFI D   D+IP YL+F+ G+VDS+DLPLN+SRE LQQ K+LKVI+K LV+K L++ +++  ++  + KF+++F   +K+G+ ED  NRN+L   ++ HS+ S   +T+  +Y+SRMK  Q++IYYI  E+ +   +S F+E+  K  +EVL+  D +DE+++  +++Y+G KL  + + G+   + E  K +   +K  F PL   +K DI   K  +E + +++RLVS+P  +V    GW+ NMER+ ++Q+ +   +     ++  KK+LEINP H ++  L   ++   N +S  DL+++ Y     ET+++SSG+ + D   +AN +  ++KL 
Sbjct:    7 SETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFM-----EALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDT-SEPLGRGSKIILFMKEDQVEYLEERKIKEIIKKHSQFIGYPIKLVLEKERDKEVSDDEAETETKKEESEEGEDKPKIEDLDDEEDDDKKDKKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEEEKKKFEEQKAAFEPLCKVMK-DILDKK--VEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSST---MGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLY-----ETSLLSSGFALEDPQIHANRIHRMIKLG 678          
The following BLAST results are available for this feature:
BLAST of Endoplasmin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HSP90B10.000e+049.32heat shock protein 90 beta family member 1 [Source... [more]
HSP90AB15.525e-16440.75heat shock protein 90 alpha family class B member ... [more]
HSP90AB15.525e-16440.75heat shock protein 90 alpha family class B member ... [more]
HSP90AB15.525e-16440.75heat shock protein 90 alpha family class B member ... [more]
HSP90AB15.525e-16440.75heat shock protein 90 alpha family class B member ... [more]
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BLAST of Endoplasmin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
enpl-10.000e+049.78Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;... [more]
enpl-10.000e+049.78Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;... [more]
enpl-10.000e+048.94Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;... [more]
enpl-10.000e+048.94Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;... [more]
enpl-10.000e+048.94Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;... [more]
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BLAST of Endoplasmin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gp930.000e+049.37gene:FBgn0039562 transcript:FBtr0085254[more]
Hsp832.332e-16740.43gene:FBgn0001233 transcript:FBtr0332873[more]
Hsp832.332e-16740.43gene:FBgn0001233 transcript:FBtr0073040[more]
Trap16.826e-8330.61gene:FBgn0026761 transcript:FBtr0086149[more]
Trap16.826e-8330.61gene:FBgn0026761 transcript:FBtr0336666[more]
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BLAST of Endoplasmin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsp90b10.000e+051.16heat shock protein 90, beta (grp94), member 1 [Sou... [more]
hsp90b10.000e+052.04heat shock protein 90, beta (grp94), member 1 [Sou... [more]
hsp90aa1.15.784e-16940.40heat shock protein 90, alpha (cytosolic), class A ... [more]
hsp90aa1.15.784e-16940.40heat shock protein 90, alpha (cytosolic), class A ... [more]
hsp90ab11.607e-16340.43heat shock protein 90, alpha (cytosolic), class A ... [more]
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BLAST of Endoplasmin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsp90b10.000e+050.68heat shock protein 90kDa beta (Grp94), member 1 [S... [more]
hsp90b10.000e+050.14heat shock protein 90kDa beta (Grp94), member 1 [S... [more]
hsp90b10.000e+054.82heat shock protein 90kDa beta (Grp94), member 1 [S... [more]
hsp90b10.000e+047.96heat shock protein 90kDa beta (Grp94), member 1 [S... [more]
hsp90b10.000e+047.53heat shock protein 90kDa beta (Grp94), member 1 [S... [more]
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BLAST of Endoplasmin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Hsp90b10.000e+049.79heat shock protein 90, beta (Grp94), member 1 [Sou... [more]
Hsp90ab17.358e-16540.75heat shock protein 90 alpha (cytosolic), class B m... [more]
Hsp90aa13.986e-16140.49heat shock protein 90, alpha (cytosolic), class A ... [more]
Hsp90aa13.986e-16140.49heat shock protein 90, alpha (cytosolic), class A ... [more]
Hsp90b11.580e-9645.85heat shock protein 90, beta (Grp94), member 1 [Sou... [more]
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BLAST of Endoplasmin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q95M18|ENPL_BOVIN0.000e+050.00Endoplasmin OS=Bos taurus OX=9913 GN=HSP90B1 PE=2 ... [more]
sp|P08113|ENPL_MOUSE0.000e+049.79Endoplasmin OS=Mus musculus OX=10090 GN=Hsp90b1 PE... [more]
sp|Q66HD0|ENPL_RAT0.000e+049.19Endoplasmin OS=Rattus norvegicus OX=10116 GN=Hsp90... [more]
sp|P08110|ENPL_CHICK0.000e+050.34Endoplasmin OS=Gallus gallus OX=9031 GN=HSP90B1 PE... [more]
sp|P41148|ENPL_CANLF0.000e+049.73Endoplasmin OS=Canis lupus familiaris OX=9615 GN=H... [more]
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BLAST of Endoplasmin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1W7RHL70.000e+050.48Endoplasmin-like protein OS=Agkistrodon contortrix... [more]
J3S4B10.000e+050.48Endoplasmin OS=Crotalus adamanteus OX=8729 PE=2 SV... [more]
T1E5V10.000e+050.34Endoplasmin-like protein OS=Crotalus horridus OX=3... [more]
A0A452E1G90.000e+049.59Heat shock protein 90 beta family member 1 OS=Capr... [more]
A0A452E1J70.000e+049.59Heat shock protein 90 beta family member 1 OS=Capr... [more]
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BLAST of Endoplasmin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsp90b10.000e+051.16heat shock protein 90, beta (grp94), member 1 [Sou... [more]
hsp90aa1.27.133e-16739.77Astyanax mexicanus heat shock protein HSP 90-alpha... [more]
hsp90aa1.27.133e-16739.77Astyanax mexicanus heat shock protein HSP 90-alpha... [more]
hsp90ab11.202e-8738.90heat shock protein 90 alpha family class B member ... [more]
trap11.673e-8631.16TNF receptor associated protein 1 [Source:NCBI gen... [more]
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BLAST of Endoplasmin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
hsp90b10.000e+046.59heat shock protein 90, beta (grp94), member 1 [Sou... [more]
ENSPMAT00000003399.11.828e-14437.95pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 ge... [more]
hsp90ab17.834e-5435.94heat shock protein 90, alpha (cytosolic), class A ... [more]
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BLAST of Endoplasmin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
HSC821.228e-15840.38Cytoplasmic chaperone of the Hsp90 family; plays a... [more]
HSP822.601e-15740.15Hsp90 chaperone; redundant in function with Hsc82p... [more]
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BLAST of Endoplasmin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO453443.288e-10368.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO456669.639e-9331.52Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
HSP906.962e-8338.24Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Endoplasmin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsp90b10.000e+050.88heat shock protein 90 beta family member 1 [Source... [more]
hsp90ab14.127e-16440.23heat shock protein 90 alpha family class B member ... [more]
hsp90aa1.24.216e-16440.20heat shock protein HSP 90-alpha [Source:NCBI gene;... [more]
hsp90aa1.27.361e-16440.06heat shock protein HSP 90-alpha [Source:NCBI gene;... [more]
hsp90aa1.21.015e-16340.23heat shock protein HSP 90-alpha [Source:NCBI gene;... [more]
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BLAST of Endoplasmin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000068132.10.000e+0100.00SMESG000068132.1[more]
SMESG000041107.10.000e+052.45SMESG000041107.1[more]
SMESG000054819.10.000e+049.93SMESG000054819.1[more]
SMESG000071533.11.799e-16640.61SMESG000071533.1[more]
SMESG000024822.11.157e-16340.93SMESG000024822.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027314 ID=SMED30027314|Name=Endoplasmin|organism=Schmidtea mediterranea sexual|type=transcript|length=2699bp
CACCAATCATCTAAAACCACTTTATAAAATACGTTATCGCGCAATACGGA
AACATGAAAATAGTTTTCAACTTGGTCATTTTGGTGATATTATTTGTTTT
GGACTTTGAATTTATTCACACTGACGAATCTGATCAAGAATCCGTTTTCC
AAGCCACCAAAGAAAGTAAAATAACCCCAGAAACGTTAGATTCAACAATT
GAAGATAATGAGATAAAACTTAAAAAAACTATGAAGGAGCCACTCTCGAA
AACTGATGACGAAGTAATTGAAAGAGAAGAAGAGGCTATTAAATTGGATG
GATTAAGTGGGGCTCAATTAAAAGAAATGCGTAAAAAAGCTGAGAAATTT
CAATTTCAAGCTGAAGTTGATCGAATGATGAAATTAATCATCAATTCACT
CTATACAAACAAAGAAATATTCCTCAGAGAATTAATTTCTAACGCGTCTG
ACGCATTGGACAAGATACGATTTATATCTTTAACGGATCCCTCAGTTTTG
GGAAACTTTCCGGAACTGTCAATCAAAATTAAAGCAGACAAAATCAATAA
TATGCTACGAATTATAGACACTGGCATCGGAATGACAAGAGATGAGTTGG
TTAAGCAGTTAGGAACGATTGCAAAATCTGGGACGACTGAGTTTCTTTCG
AAAATAGAAAAGGAAAAAACAGAAAATACGAGTGATTTTATTGGACAATT
CGGAGTTGGATTCTATTCAGTTTATCTTGTTGCGGATAGTGTAACAGTGA
TATCGAAAAATAACAATGACGATCAGTATATTTGGGAGTCTGATTCTTCC
AACACGTTCTCCGTTACAAAGGATCCAAGAGGAAATACACTTGGACGTGG
GACTGAAATAGTTTTACGTTTGAAACCATCCGCCAGTGAATATTTAGAAT
CAGAAAATTTACGCCGTCTCGTTCGACAATATAGTCAATATTTGAGTTTT
CCTATCTATCTTTGGACATCCAAGACTAGCGAAGAAAACTCTTTGAAAAA
GACAAATGAAGTGAAAGCTGACTCTAAAGATGATGAATCCGCAACAGTGA
CAGACGAAGAACCTAAATCAGATGTTTCACCACCAAAGAAATCATCAGTA
GTGTGGGATTGGGAAAGAATTAATTCACAAAAACCTATTTGGACCCGTAA
ACCAGCCGAAGTAAGTGAAGAAGAATACAACGAATTCTTTAAAACATTGC
TGAAAAGTGATGACAAACCCTTATCGAAAATACATTTTAATGCAGAAGGA
GAGGTTTCATTCAAATCTTTATTATATATACCATCGAAGGCGCCAGCAAA
CCTATTTGAAAGAGAAATCAAGGATTCATCAATAAGACTTTATGTGAGAA
GGGTATTCATTACTGATAAAATTCGAGACATAATCCCAAGATATTTAAGT
TTCATAATTGGAATAGTAGATAGTGATGATTTACCCTTGAACGTTTCTAG
AGAAACGCTTCAACAAGAAAAGTTATTGAAGGTGATCCAAAAGAAATTGG
TTAGAAAAGTGTTGGATATGATTAAAAAACTTAAAAGTGAACAATTTGGC
AAATTTTGGAAAGAATTTCGGGCAGGTATCAAAATGGGTTTGATTGAAGA
TGACACTAATAGAAACCGCTTGACTAAACTCATCCAAATGCATAGTAGCA
AATCATTAGCAAACCTAACAACTTTTGCTGAATATGTTTCCCGAATGAAA
TCCCAACAGGAAGAGATATACTATATTGTTGAGGAAAATCTAGAACAAGC
TAAAAACTCACCATTTATCGAAAAATTCTTGAAATATGACTATGAAGTTT
TATTTTTCACAGATACATTAGACGAGCACGCTTTACACCTAATGGAAAAG
TATGAAGGTACCAAATTATCTAATCTGGCGCGAGGAGGAATATTTTTCGA
CAAAACAGAAGGATCAAAGTCAAGGTTAAATAATAAAAAAAATGAATTTA
GACCACTGATAGATTTCATAAAAACCGATATTGAGCCTGGGAAAGAATTT
ATTGAAAATATTGTTTTAACTGATCGTTTAGTTTCAGCTCCAATGATGGT
TGTTCCCCAAGATCAAGGCTGGACAGGGAACATGGAAAGGTTGGCTCGTT
CCCAGTCAGGCAAACAAGAAGAATCTGGAGTGATTCAGCAGCATATAAAA
GTGAAAAAAAATTTAGAAATAAATCCTAAGCATCCTATAATTATTAAATT
AAATAATCTTATTAATAATCACGCAAATCCTAGAAGTGATTTATTGCTAA
TAAATTATGCTCAATCTCTTCTTGAAACTGCTATTATCAGTTCGGGTTAC
TTAGTAAGTGACGTAACAAAATACGCAAATATGGTAGAGGATATACTGAA
GTTAAATTATAAGGATCAAGGAAATTTGCATGATGATGCTAATGAAGAAG
ATGATTCAAACGAAAATAAAGAAAATTCATTTGAGTACGATGAGAAGCTA
GCTCATGCTGTACCTAGAGATGCTAATAACTATGCATCGGATGAAAGTGA
TGATTTTGATGATGTAGACTCTAGCAGTTCAGCCGCTGAACCACAAAATC
CTCAAACCAATTCTGGAAATATAAATGAAAAAAAAATGGTAGAAGAGATT
CACGATGATCTTTAAAAGGATATCATAAACAATTTTGTCACTATTTAATT
GTTTGAATTATTCGTTTAAATAAATCTTTTAAATTTCGACTAAAAAAAA
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protein sequence of SMED30027314-orf-1

>SMED30027314-orf-1 ID=SMED30027314-orf-1|Name=SMED30027314-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=854bp
MKIVFNLVILVILFVLDFEFIHTDESDQESVFQATKESKITPETLDSTIE
DNEIKLKKTMKEPLSKTDDEVIEREEEAIKLDGLSGAQLKEMRKKAEKFQ
FQAEVDRMMKLIINSLYTNKEIFLRELISNASDALDKIRFISLTDPSVLG
NFPELSIKIKADKINNMLRIIDTGIGMTRDELVKQLGTIAKSGTTEFLSK
IEKEKTENTSDFIGQFGVGFYSVYLVADSVTVISKNNNDDQYIWESDSSN
TFSVTKDPRGNTLGRGTEIVLRLKPSASEYLESENLRRLVRQYSQYLSFP
IYLWTSKTSEENSLKKTNEVKADSKDDESATVTDEEPKSDVSPPKKSSVV
WDWERINSQKPIWTRKPAEVSEEEYNEFFKTLLKSDDKPLSKIHFNAEGE
VSFKSLLYIPSKAPANLFEREIKDSSIRLYVRRVFITDKIRDIIPRYLSF
IIGIVDSDDLPLNVSRETLQQEKLLKVIQKKLVRKVLDMIKKLKSEQFGK
FWKEFRAGIKMGLIEDDTNRNRLTKLIQMHSSKSLANLTTFAEYVSRMKS
QQEEIYYIVEENLEQAKNSPFIEKFLKYDYEVLFFTDTLDEHALHLMEKY
EGTKLSNLARGGIFFDKTEGSKSRLNNKKNEFRPLIDFIKTDIEPGKEFI
ENIVLTDRLVSAPMMVVPQDQGWTGNMERLARSQSGKQEESGVIQQHIKV
KKNLEINPKHPIIIKLNNLINNHANPRSDLLLINYAQSLLETAIISSGYL
VSDVTKYANMVEDILKLNYKDQGNLHDDANEEDDSNENKENSFEYDEKLA
HAVPRDANNYASDESDDFDDVDSSSSAAEPQNPQTNSGNINEKKMVEEIH
DDL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0001666response to hypoxia
GO:0030433ubiquitin-dependent ERAD pathway
GO:0030970retrograde protein transport, ER to cytosol
GO:0031247actin rod assembly
GO:0043066negative regulation of apoptotic process
GO:0043666regulation of phosphoprotein phosphatase activity
GO:0071318cellular response to ATP
GO:0006457protein folding
GO:0006950response to stress
GO:0006880intracellular sequestering of iron ion
Vocabulary: molecular function
TermDefinition
GO:0003723RNA binding
GO:0019903protein phosphatase binding
GO:0050750low-density lipoprotein particle receptor binding
GO:0051082unfolded protein binding
GO:0005524ATP binding
GO:0000166nucleotide binding
Vocabulary: cellular component
TermDefinition
GO:0005789endoplasmic reticulum membrane
GO:0005829cytosol
GO:0016529sarcoplasmic reticulum
GO:0030496midbody
GO:0032991macromolecular complex
GO:0033018sarcoplasmic reticulum lumen
GO:0042470melanosome
GO:0005783endoplasmic reticulum
GO:0005788endoplasmic reticulum lumen
GO:0048471perinuclear region of cytoplasm
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002089reproductive organ
PLANA:0003116parenchymal cell
PLANA:0003304testis primordium
Vocabulary: INTERPRO
TermDefinition
IPR037196HSP90_C
IPR036890HATPase_C_sf
IPR020575Hsp90_N
IPR003594HATPase_C
IPR001404Hsp90_fam
IPR019805Heat_shock_protein_90_CS
IPR020568Ribosomal_S5_D2-typ_fold
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR020575Heat shock protein Hsp90, N-terminalPRINTSPR00775HEATSHOCK90coord: 265..282
score: 53.93
coord: 283..301
score: 31.42
coord: 185..202
score: 57.35
coord: 97..117
score: 57.44
coord: 118..140
score: 87.22
coord: 167..184
score: 56.58
coord: 213..235
score: 78.53
IPR003594Histidine kinase/HSP90-like ATPaseSMARTSM00387HKATPase_4coord: 119..277
e-value: 1.1E-5
score: 34.8
IPR003594Histidine kinase/HSP90-like ATPasePFAMPF02518HATPase_ccoord: 119..275
e-value: 2.7E-11
score: 44.0
NoneNo IPR availableGENE3DG3DSA:3.40.50.11260coord: 524..611
e-value: 1.4E-26
score: 94.2
NoneNo IPR availableGENE3DG3DSA:3.30.70.2140coord: 306..339
e-value: 1.8E-102
score: 343.9
NoneNo IPR availableGENE3DG3DSA:3.30.230.80coord: 357..523
e-value: 1.6E-69
score: 235.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 779..853
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 824..842
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 313..342
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 313..346
NoneNo IPR availablePANTHERPTHR11528:SF97ENDOPLASMINcoord: 73..790
NoneNo IPR availableCDDcd16927HATPase_Hsp90-likecoord: 107..297
e-value: 1.48952E-90
score: 282.102
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..23
score: 0.722
IPR001404Heat shock protein Hsp90 familyPFAMPF00183HSP90coord: 279..790
e-value: 1.5E-166
score: 555.3
IPR001404Heat shock protein Hsp90 familyPIRSFPIRSF002583HSP90_HTPGcoord: 28..807
e-value: 5.8E-225
score: 746.6
IPR001404Heat shock protein Hsp90 familyPANTHERPTHR11528HEAT SHOCK PROTEIN 90 FAMILY MEMBERcoord: 73..790
IPR037196HSP90, C-terminal domainGENE3DG3DSA:1.20.120.790coord: 613..769
e-value: 3.1E-32
score: 113.4
IPR037196HSP90, C-terminal domainSUPERFAMILYSSF110942HSP90 C-terminal domaincoord: 648..765
IPR036890Histidine kinase/HSP90-like ATPase superfamilyGENE3DG3DSA:3.30.565.10coord: 97..305
e-value: 1.8E-102
score: 343.9
IPR036890Histidine kinase/HSP90-like ATPase superfamilySUPERFAMILYSSF55874ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinasecoord: 97..308
IPR019805Heat shock protein Hsp90, conserved sitePROSITEPS00298HSP90coord: 117..126
IPR020568Ribosomal protein S5 domain 2-type foldSUPERFAMILYSSF54211Ribosomal protein S5 domain 2-likecoord: 359..609