semaphorin-like protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30027306 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 18Note: Hover over icons to view figure legend
Homology
BLAST of semaphorin-like protein vs. TrEMBL
Match: A0A0K0LJ47 (Semaphorin-like protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=semal PE=2 SV=1) HSP 1 Score: 607.446 bits (1565), Expect = 0.000e+0 Identity = 286/295 (96.95%), Postives = 290/295 (98.31%), Query Frame = 2 Query: 1880 PTAERKQFSPLMIVNIISTHGHLYRVVLCDFDNGIRNHGEDKYSGQWYNWCIFRFTDQPYLYRQYTPMESRERGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGWQ 2764 P AERKQFSPLMIVNIISTHGHLYRVVLCDFDNG+RNHGEDK SGQWYNWCIFRFTDQPYLYRQYTPMESR+RGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIK NENVDTRT+KLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVY+G Q Sbjct: 1 PIAERKQFSPLMIVNIISTHGHLYRVVLCDFDNGMRNHGEDKSSGQWYNWCIFRFTDQPYLYRQYTPMESRKRGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIKTTNENVDTRTSKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYEGGQ 295
BLAST of semaphorin-like protein vs. Planmine SMEST
Match: SMESG000016256.1 (SMESG000016256.1) HSP 1 Score: 1546.95 bits (4004), Expect = 0.000e+0 Identity = 749/804 (93.16%), Postives = 769/804 (95.65%), Query Frame = 2 Query: 554 MSCSRYEDEPMVTYRDKLNNLYVASGWGLYRXXXXXXXXXXNNSTMLYADWKLYRNLFTLPSAMAWVLSSDVNFINVVKETDNHLYFFGHEINNQYGLNNQEDRHAWQSFMVRICKNDLGFKYLPSDILNTLKRLTSKEYASPTFYPPDTMVQEDFMVSLTHEYIDFNSDWYDGTAHLPKTHFVTPIKVNFGCYIGRRPRGISDNHHWGDTNVIYMNQLADVIFDPDRKIRFSTKSGDSSLGCTGKMHEQIPLVGIFNREGLSGTNVEPSGALCQLQINENIFVEMGSQREQYRVQNYNGVENAYEDIMRFSSTSYSNFYSRTIHRTNGYTLHPYWNQGVSIGGSYRERPFAEVGKCQTPSFYKNLNAEKFLKIQNFSNLAWPNELPNRLSSISSSFCQYSAAELYSFNASFVLPGIKFKKLFLVRENISNYAMNDIKNPTMPTAERKQFSPLMIVNIISTHGHLYRVVLCDFDNGIRNHGEDKYSGQWYNWCIFRFTDQPYLYRQYTPMESRERGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGWQPVNGWKVTAICLILLFLLAPIGALIYRFRNNLNDLLRSKQKPPSPTAKNQRVPLNESAQESKNPKIV 2965 MSCSRYEDEPMVTYRDKLNNLYVASGWGLYRPDKKDPDVPDNNSTMLYADWKLYRNLFTLPS+MAWVLSSDVNFINVVKETDNHLYFFGHEINNQYGLNNQEDRHAWQSFMVRICK+DLGFKYLP ++L L +TS Y+ TFYPPDT EDFMVS H IDFNS WYDGTAHLPKTHFVTPIKVNFGCYIGRRPR ISDNHHWGDTNVIYMNQLADVIFDPDRKIRFSTKSGD SLGC GKMHEQIPLVGIFNREGLSGTNVEPSGALCQLQINENIFVEMGSQREQYRVQNYNGVENAYEDIMRFSSTSYSNFYSRTIHRTNGYTLHPYWNQGVSIG Y++ FAEVGKCQTPSFYK LN EKFLKIQNFSNLAWPNELPNRLSS+ SSFCQYSAAELYSFNASFVLPG++FKKLFLV+ENISNYAM DIK+ T+P AERKQFSPLMIVNIISTHGHLYRVVLCDFDNG+RNHGEDK SGQWYNWCIFRFTDQPYLYRQYTPME+R+RGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHV+TTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIK E++DTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITK DYSTQLLSVYKGWQPVNGWKVTAICLILLFLLAPIGALIYRFRNNLNDLLRSKQKPPSPTAKNQRVPLNESAQESKNPKIV Sbjct: 1 MSCSRYEDEPMVTYRDKLNNLYVASGWGLYRPDKKDPDVPDNNSTMLYADWKLYRNLFTLPSSMAWVLSSDVNFINVVKETDNHLYFFGHEINNQYGLNNQEDRHAWQSFMVRICKDDLGFKYLPREMLTDLNPITSVYYSMATFYPPDTTSMEDFMVSPNHANIDFNSSWYDGTAHLPKTHFVTPIKVNFGCYIGRRPRAISDNHHWGDTNVIYMNQLADVIFDPDRKIRFSTKSGDISLGCKGKMHEQIPLVGIFNREGLSGTNVEPSGALCQLQINENIFVEMGSQREQYRVQNYNGVENAYEDIMRFSSTSYSNFYSRTIHRTNGYTLHPYWNQGVSIGDPYKDGSFAEVGKCQTPSFYKILNVEKFLKIQNFSNLAWPNELPNRLSSMPSSFCQYSAAELYSFNASFVLPGLRFKKLFLVKENISNYAMKDIKSETIPIAERKQFSPLMIVNIISTHGHLYRVVLCDFDNGMRNHGEDKSSGQWYNWCIFRFTDQPYLYRQYTPMENRKRGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVVTTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIKTVYESIDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKGDYSTQLLSVYKGWQPVNGWKVTAICLILLFLLAPIGALIYRFRNNLNDLLRSKQKPPSPTAKNQRVPLNESAQESKNPKIV 804
BLAST of semaphorin-like protein vs. Planmine SMEST
Match: SMESG000016256.1 (SMESG000016256.1) HSP 1 Score: 1540.4 bits (3987), Expect = 0.000e+0 Identity = 748/805 (92.92%), Postives = 769/805 (95.53%), Query Frame = 2 Query: 554 MSCSRYEDEPMVTYRDKLNNLYVASGWGLYRXXXXXXXXXXNNSTMLYADWKLYRNLFTLPSAMAWVLSSDVNFINVVKETDNHLYFFGHEINNQYGLNNQEDRHAWQSFMVRICKNDLGFKYLPSDILNTLKRLTSKEYASPTFYPPDTMVQEDFMVSLTHEYIDFNSDWYDGTAHLPKTHFVTPIKVNFGCYIGRRPRGISDNHHWGDTNVIYMNQLADVIFDPDRKIRFSTKSGDSSLGCTGKMHEQIPLVGIFNREGLSGTNVEPSGALCQLQINENIFVEMGSQREQYRVQNYNGVENAYEDIMRFSSTSYSNFYSRTIHRTNGYTLHPYWNQGVSIGGSYRERPFAEVGKCQTPSFYKNLNAEKFLKIQNFSNLAWPNELPNRLSSISSSFCQYSAAELYSFNASFVLPGIKFKKLFLVRENISNYAMNDIKNPTMPTAERKQFSPLMIVNIISTHGHLYRVVLCDFDNGIRNHGEDKYSGQWYNWCIFRFTDQPYLYRQYTPMESRERGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGWQPVNGWKVTAICLILLFLLAPIGALIYRFRNNLNDLLRSKQKPPSPTAKN-QRVPLNESAQESKNPKIV 2965 MSCSRYEDEPMVTYRDKLNNLYVASGWGLYRPDKKDPDVPDNNSTMLYADWKLYRNLFTLPS+MAWVLSSDVNFINVVKETDNHLYFFGHEINNQYGLNNQEDRHAWQSFMVRICK+DLGFKYLP ++L L +TS Y+ TFYPPDT EDFMVS H IDFNS WYDGTAHLPKTHFVTPIKVNFGCYIGRRPR ISDNHHWGDTNVIYMNQLADVIFDPDRKIRFSTKSGD SLGC GKMHEQIPLVGIFNREGLSGTNVEPSGALCQLQINENIFVEMGSQREQYRVQNYNGVENAYEDIMRFSSTSYSNFYSRTIHRTNGYTLHPYWNQGVSIG Y++ FAEVGKCQTPSFYK LN EKFLKIQNFSNLAWPNELPNRLSS+ SSFCQYSAAELYSFNASFVLPG++FKKLFLV+ENISNYAM DIK+ T+P AERKQFSPLMIVNIISTHGHLYRVVLCDFDNG+RNHGEDK SGQWYNWCIFRFTDQPYLYRQYTPME+R+RGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHV+TTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIK E++DTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITK DYSTQLLSVYKGWQPVNGWKVTAICLILLFLLAPIGALIYRFRNNLNDLLRSKQKPPSPTAKN +RVPLNESAQESKNPKIV Sbjct: 1 MSCSRYEDEPMVTYRDKLNNLYVASGWGLYRPDKKDPDVPDNNSTMLYADWKLYRNLFTLPSSMAWVLSSDVNFINVVKETDNHLYFFGHEINNQYGLNNQEDRHAWQSFMVRICKDDLGFKYLPREMLTDLNPITSVYYSMATFYPPDTTSMEDFMVSPNHANIDFNSSWYDGTAHLPKTHFVTPIKVNFGCYIGRRPRAISDNHHWGDTNVIYMNQLADVIFDPDRKIRFSTKSGDISLGCKGKMHEQIPLVGIFNREGLSGTNVEPSGALCQLQINENIFVEMGSQREQYRVQNYNGVENAYEDIMRFSSTSYSNFYSRTIHRTNGYTLHPYWNQGVSIGDPYKDGSFAEVGKCQTPSFYKILNVEKFLKIQNFSNLAWPNELPNRLSSMPSSFCQYSAAELYSFNASFVLPGLRFKKLFLVKENISNYAMKDIKSETIPIAERKQFSPLMIVNIISTHGHLYRVVLCDFDNGMRNHGEDKSSGQWYNWCIFRFTDQPYLYRQYTPMENRKRGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVVTTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIKTVYESIDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKGDYSTQLLSVYKGWQPVNGWKVTAICLILLFLLAPIGALIYRFRNNLNDLLRSKQKPPSPTAKNPERVPLNESAQESKNPKIV 805
BLAST of semaphorin-like protein vs. Planmine SMEST
Match: SMESG000016292.1 (SMESG000016292.1) HSP 1 Score: 1362.05 bits (3524), Expect = 0.000e+0 Identity = 666/967 (68.87%), Postives = 781/967 (80.77%), Query Frame = 2 Query: 29 VIIALTALYLCIRFSKAYTMIKQIDNYIYIGGKNVLDKYIEDNGKLELKVRYQYVWDSQIMNGSDIGFQFHIKQWPVNYSRGPQGYAFDTCLNWKQEHLNATVRDSAFDFQHWRYHTPSGDWLVMNYSCMNSFIKSVEKYDNNTLWVCGTFGAFPRAFSVDINTLKFIKFVDVNVMSCSRYEDEPMVTYRDKLNNLYVASGWGLYRXXXXXXXXXXNNSTMLYADWKLYRNLFTLPSAMAWVLSSDVNFINVVKETDNHLYFFGHEINNQYGLNNQEDRHAWQSFMVRICKNDLGFKYLPSDILNTLKRLTSKEYASPTFYPPDTMVQEDFMVSLTHEYIDFNSDWYDGTAHLPKTHFVTPIKVNFGCYIGRRPRGISDNHHWGDTNVIYMNQLADVIFDPDRKIRFSTKSGDSSLGCTGKMHEQIPLVGIFNREGLSGTNVEPSGALCQLQINENIFVEMGSQREQYRVQNYNGVENAYEDIMRFSSTSYSNFYSRTIHRTNGYTLHPYWNQGVSIGGS----YRERPFAEVGKCQTPSFYKNLNAEKFLKIQNFSNLAWPNELPNRLSSISSSFCQYSAAELYSFNASFVLPGIKFKKLFLVRENISNYAMNDIKNPTMPT-AERKQFSPLMIVNIISTHGHLYRVVLCDFDNGIRNHGEDKYSGQWYNWCIFRFTDQPYLYRQYTPMESRERGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGWQPVNGWKVT--AICLILLFLLAPIGALIYRFRNNLNDLLRSKQKPPSPTAK 2908 + A+ L + S Y+++K+ID +Y+GG+N L Y N KL V Y + +I NGSDIGF+F I ++P + P AFDTCLNWKQ HLN + R+SAFD+QH YHTPSGDW M++ CMNSFIK +EK DN TLWVCGTFG+FPRAFSV ++LKFIKF+DVN+MSC+RY DEPMV+YRD+L+NLY+ SGWGLY+PDK +PDVP+NNSTM+Y+DW+L+RNLFTLPSAMAWVLSSDV+FINVVKET+ HLYFFGHEINNQYGLNNQEDR+AWQSFMVRICKND+GFK +P +K + S FY ++ + D+ +S TH+ N DW+ T HLP HF + K+NFGCYIG+RPR ISDN+ WG TNV+Y+N L DVIFDP++ I+F TK+ + GC+ + HEQIPL+G+FN G+ GT + +GALCQLQIN NIF E+GS+++ Y + N +AYE++M +S S SNFYSRT+HRT+G T++PYWNQGV IG + Y + F +GKCQ SF+K L +KFLKI NFSN WPNELPNRLSSI S+ CQ+SAAELYSFNA+ ++PG++F+ +FLV +NI+NY M++++ T RK FSPLM V IISTHGHLYRVVLCDFDNG+RNHGEDK SGQWYNWCIFRFTDQPYLYRQYTPMESR+RGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCA+FIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGW PVN WK+T +I L L+A IGAL+Y FRN+ N +PP ++ Sbjct: 2 IFSAIMFLEILSFISTDYSVVKEIDGVVYVGGRNSLSSYQSINEKLLPLVNETYKFPPEIFNGSDIGFEFKILEFPSEITNNPTSLAFDTCLNWKQNHLNDSYRNSAFDYQHRNYHTPSGDWETMDFICMNSFIKGIEKLDNTTLWVCGTFGSFPRAFSVWKDSLKFIKFIDVNLMSCARYTDEPMVSYRDQLDNLYIGSGWGLYKPDKSNPDVPNNNSTMMYSDWRLFRNLFTLPSAMAWVLSSDVHFINVVKETEKHLYFFGHEINNQYGLNNQEDRNAWQSFMVRICKNDVGFKSVP------MKEAWLMRHMSGHFYNIGSIGEFDYTLSPTHDEAGHNPDWFHNTVHLPTKHFTSSQKINFGCYIGKRPRSISDNYFWGQTNVLYLNMLVDVIFDPNKTIKFKTKNNNKYFGCSKEPHEQIPLIGLFNSPGIRGTAMSSTGALCQLQINSNIFNEIGSKKKPYHLTNILKANDAYEELMLLNSVSVSNFYSRTLHRTSGLTIYPYWNQGVLIGDNVHRKYYKNVFDNIGKCQNSSFFKTLTKDKFLKIMNFSNTGWPNELPNRLSSIPSAVCQFSAAELYSFNATVLIPGVEFRNVFLVADNITNYYMHELEIATTENPGHRKIFSPLMTVIIISTHGHLYRVVLCDFDNGMRNHGEDKSSGQWYNWCIFRFTDQPYLYRQYTPMESRKRGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAKFIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGWHPVNKWKLTAIFFIIITLILIAVIGALLYWFRNHPNYHQGRTDEPPGAVSE 962
BLAST of semaphorin-like protein vs. Planmine SMEST
Match: SMESG000016292.1 (SMESG000016292.1) HSP 1 Score: 1360.13 bits (3519), Expect = 0.000e+0 Identity = 664/953 (69.67%), Postives = 776/953 (81.43%), Query Frame = 2 Query: 71 SKAYTMIKQIDNYIYIGGKNVLDKYIEDNGKLELKVRYQYVWDSQIMNGSDIGFQFHIKQWPVNYSRGPQGYAFDTCLNWKQEHLNATVRDSAFDFQHWRYHTPSGDWLVMNYSCMNSFIKSVEKYDNNTLWVCGTFGAFPRAFSVDINTLKFIKFVDVNVMSCSRYEDEPMVTYRDKLNNLYVASGWGLYRXXXXXXXXXXNNSTMLYADWKLYRNLFTLPSAMAWVLSSDVNFINVVKETDNHLYFFGHEINNQYGLNNQEDRHAWQSFMVRICKNDLGFKYLPSDILNTLKRLTSKEYASPTFYPPDTMVQEDFMVSLTHEYIDFNSDWYDGTAHLPKTHFVTPIKVNFGCYIGRRPRGISDNHHWGDTNVIYMNQLADVIFDPDRKIRFSTKSGDSSLGCTGKMHEQIPLVGIFNREGLSGTNVEPSGALCQLQINENIFVEMGSQREQYRVQNYNGVENAYEDIMRFSSTSYSNFYSRTIHRTNGYTLHPYWNQGVSIGGS----YRERPFAEVGKCQTPSFYKNLNAEKFLKIQNFSNLAWPNELPNRLSSISSSFCQYSAAELYSFNASFVLPGIKFKKLFLVRENISNYAMNDIKNPTMPT-AERKQFSPLMIVNIISTHGHLYRVVLCDFDNGIRNHGEDKYSGQWYNWCIFRFTDQPYLYRQYTPMESRERGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGWQPVNGWKVT--AICLILLFLLAPIGALIYRFRNNLNDLLRSKQKPPSPTAK 2908 S Y+++K+ID +Y+GG+N L Y N KL V Y + +I NGSDIGF+F I ++P + P AFDTCLNWKQ HLN + R+SAFD+QH YHTPSGDW M++ CMNSFIK +EK DN TLWVCGTFG+FPRAFSV ++LKFIKF+DVN+MSC+RY DEPMV+YRD+L+NLY+ SGWGLY+PDK +PDVP+NNSTM+Y+DW+L+RNLFTLPSAMAWVLSSDV+FINVVKET+ HLYFFGHEINNQYGLNNQEDR+AWQSFMVRICKND+GFK +P +K + S FY ++ + D+ +S TH+ N DW+ T HLP HF + K+NFGCYIG+RPR ISDN+ WG TNV+Y+N L DVIFDP++ I+F TK+ + GC+ + HEQIPL+G+FN G+ GT + +GALCQLQIN NIF E+GS+++ Y + N +AYE++M +S S SNFYSRT+HRT+G T++PYWNQGV IG + Y + F +GKCQ SF+K L +KFLKI NFSN WPNELPNRLSSI S+ CQ+SAAELYSFNA+ ++PG++F+ +FLV +NI+NY M++++ T RK FSPLM V IISTHGHLYRVVLCDFDNG+RNHGEDK SGQWYNWCIFRFTDQPYLYRQYTPMESR+RGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCA+FIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGW PVN WK+T +I L L+A IGAL+Y FRN+ N +PP ++ Sbjct: 10 STDYSVVKEIDGVVYVGGRNSLSSYQSINEKLLPLVNETYKFPPEIFNGSDIGFEFKILEFPSEITNNPTSLAFDTCLNWKQNHLNDSYRNSAFDYQHRNYHTPSGDWETMDFICMNSFIKGIEKLDNTTLWVCGTFGSFPRAFSVWKDSLKFIKFIDVNLMSCARYTDEPMVSYRDQLDNLYIGSGWGLYKPDKSNPDVPNNNSTMMYSDWRLFRNLFTLPSAMAWVLSSDVHFINVVKETEKHLYFFGHEINNQYGLNNQEDRNAWQSFMVRICKNDVGFKSVP------MKEAWLMRHMSGHFYNIGSIGEFDYTLSPTHDEAGHNPDWFHNTVHLPTKHFTSSQKINFGCYIGKRPRSISDNYFWGQTNVLYLNMLVDVIFDPNKTIKFKTKNNNKYFGCSKEPHEQIPLIGLFNSPGIRGTAMSSTGALCQLQINSNIFNEIGSKKKPYHLTNILKANDAYEELMLLNSVSVSNFYSRTLHRTSGLTIYPYWNQGVLIGDNVHRKYYKNVFDNIGKCQNSSFFKTLTKDKFLKIMNFSNTGWPNELPNRLSSIPSAVCQFSAAELYSFNATVLIPGVEFRNVFLVADNITNYYMHELEIATTENPGHRKIFSPLMTVIIISTHGHLYRVVLCDFDNGMRNHGEDKSSGQWYNWCIFRFTDQPYLYRQYTPMESRKRGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAKFIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINEKLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGWHPVNKWKLTAIFFIIITLILIAVIGALLYWFRNHPNYHQGRTDEPPGAVSE 956
BLAST of semaphorin-like protein vs. Planmine SMEST
Match: SMESG000016292.1 (SMESG000016292.1) HSP 1 Score: 1344.72 bits (3479), Expect = 0.000e+0 Identity = 663/980 (67.65%), Postives = 776/980 (79.18%), Query Frame = 2 Query: 71 SKAYTMIKQIDNYIYIGGKNVLDKYIEDNGKLELKVRYQYVWDSQIMNGSDIGFQFHIKQWPVNYSRGPQGYAFDTCLNWKQEHLNATVRDSAFDFQHWRYHTPSGDWLVMNYSCMNSFIKSVEKYDNNTLWVCGTFGAFPRAFSVDINTLKFIKFVDVNVMSCSRYEDEPMVTYRDKLNNLYVASGWGLYRXXXXXXXXXXNNSTMLYADWKLYRNLFTLPSAMAWVLSSDVNFINVVKETDNHLYFFGHEINNQYGLNNQEDRHAWQSFMVRICKNDLGFKYLPSDILNTLKRLTSKEYASPTFYPPDTMVQEDFMVSLTHEYIDFNSDWYDGTAHLPKTHFVTPIKVNFGCYIGRRPRGISDNHHWGDTNVIYMNQLADVIFDPDRKIRFSTKSGDSSLGCTGKMHEQIPLVGIFNREGLSGTNVEPSGALCQLQINENIFVEMGSQREQYRVQNYNGVENAYEDIMRFSSTSYSNFYSRTIHRTNGYTLHPYWNQGVSIGGS----YRERPFAEVGKCQTPSFYKNLNAEKFLKIQNFSNLAWPNELPNRLSSISSSFCQYSAAELYSFNASFVLPGIKFKKLFLVRENISNYAMNDIKNPTMPT-AERKQFSPLMIVNIISTHGHLYRVVLCDFDNGIRNHGEDKYSGQWYNWCIFRFTDQPYLYRQYTPMESRERGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAQFIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINE---------------------------KLVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGWQPVNGWKVT--AICLILLFLLAPIGALIYRFRNNLNDLLRSKQKPPSPTAK 2908 S Y+++K+ID +Y+GG+N L Y N KL V Y + +I NGSDIGF+F I ++P + P AFDTCLNWKQ HLN + R+SAFD+QH YHTPSGDW M++ CMNSFIK +EK DN TLWVCGTFG+FPRAFSV ++LKFIKF+DVN+MSC+RY DEPMV+YRD+L+NLY+ SGWGLY+PDK +PDVP+NNSTM+Y+DW+L+RNLFTLPSAMAWVLSSDV+FINVVKET+ HLYFFGHEINNQYGLNNQEDR+AWQSFMVRICKND+GFK +P +K + S FY ++ + D+ +S TH+ N DW+ T HLP HF + K+NFGCYIG+RPR ISDN+ WG TNV+Y+N L DVIFDP++ I+F TK+ + GC+ + HEQIPL+G+FN G+ GT + +GALCQLQIN NIF E+GS+++ Y + N +AYE++M +S S SNFYSRT+HRT+G T++PYWNQGV IG + Y + F +GKCQ SF+K L +KFLKI NFSN WPNELPNRLSSI S+ CQ+SAAELYSFNA+ ++PG++F+ +FLV +NI+NY M++++ T RK FSPLM V IISTHGHLYRVVLCDFDNG+RNHGEDK SGQWYNWCIFRFTDQPYLYRQYTPMESR+RGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCA+FIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINE +LVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGW PVN WK+T +I L L+A IGAL+Y FRN+ N +PP ++ Sbjct: 10 STDYSVVKEIDGVVYVGGRNSLSSYQSINEKLLPLVNETYKFPPEIFNGSDIGFEFKILEFPSEITNNPTSLAFDTCLNWKQNHLNDSYRNSAFDYQHRNYHTPSGDWETMDFICMNSFIKGIEKLDNTTLWVCGTFGSFPRAFSVWKDSLKFIKFIDVNLMSCARYTDEPMVSYRDQLDNLYIGSGWGLYKPDKSNPDVPNNNSTMMYSDWRLFRNLFTLPSAMAWVLSSDVHFINVVKETEKHLYFFGHEINNQYGLNNQEDRNAWQSFMVRICKNDVGFKSVP------MKEAWLMRHMSGHFYNIGSIGEFDYTLSPTHDEAGHNPDWFHNTVHLPTKHFTSSQKINFGCYIGKRPRSISDNYFWGQTNVLYLNMLVDVIFDPNKTIKFKTKNNNKYFGCSKEPHEQIPLIGLFNSPGIRGTAMSSTGALCQLQINSNIFNEIGSKKKPYHLTNILKANDAYEELMLLNSVSVSNFYSRTLHRTSGLTIYPYWNQGVLIGDNVHRKYYKNVFDNIGKCQNSSFFKTLTKDKFLKIMNFSNTGWPNELPNRLSSIPSAVCQFSAAELYSFNATVLIPGVEFRNVFLVADNITNYYMHELEIATTENPGHRKIFSPLMTVIIISTHGHLYRVVLCDFDNGMRNHGEDKSSGQWYNWCIFRFTDQPYLYRQYTPMESRKRGQSVQFRASSLLLDKKIVTSEDESRFPINRDPQFHVVKDVLRKGNHLHVITTNNIRTVNMEINCAKDYATCIDCASDPDCMWNNGNKKCIKYNEAESQKESIVQDVLDRGFKCAKFIKAANENVDTRTNKLPLTIYCNNSEYWRGEIQWKINEIVQFYDFIFLVEIYFFPILLISFHNVAELVGNDPDQFIIHTDQKYLTILHVNNSIKSVKCHGVKEDHDKLFNGAEYDWITKRDYSTQLLSVYKGWHPVNKWKLTAIFFIIITLILIAVIGALLYWFRNHPNYHQGRTDEPPGAVSE 983 The following BLAST results are available for this feature:
BLAST of semaphorin-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of semaphorin-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of semaphorin-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of semaphorin-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 0
BLAST of semaphorin-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of semaphorin-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of semaphorin-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 0
BLAST of semaphorin-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 1
BLAST of semaphorin-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of semaphorin-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of semaphorin-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of semaphorin-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of semaphorin-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of semaphorin-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30027306 ID=SMED30027306|Name=semaphorin-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3492bpback to top protein sequence of SMED30027306-orf-1 >SMED30027306-orf-1 ID=SMED30027306-orf-1|Name=SMED30027306-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=982bp MNVIIALTALYLCIRFSKAYTMIKQIDNYIYIGGKNVLDKYIEDNGKLELback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|