Troponin C, skeletal muscle

Overview
NameTroponin C, skeletal muscle
Smed IDSMED30027301
Length (bp)835
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Troponin C, skeletal muscle (SMED30027301) t-SNE clustered cells

Violin plots show distribution of expression levels for Troponin C, skeletal muscle (SMED30027301) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Troponin C, skeletal muscle (SMED30027301) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Troponin C, skeletal muscle (SMED30027301) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30027301

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30027301h1SMcG0005090 dd_Smed_v4_5491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30027301h1SMcG0005090 dd_Smed_v4_5491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30027301h1SMcG0005090 dd_Smed_v4_5491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30027301h1SMcG0005090 dd_Smed_v4_5491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30027301h1SMcG0005090 dd_Smed_v4_5491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30027301h1SMcG0005090 dd_Smed_v4_5491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30027301h1SMcG0005090 dd_Smed_v4_5491_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30027301h1SMcG0005090 dd_Smed_v6_5491_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30027301h1SMcG0005090 dd_Smed_v4_5491_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
ventral epidermisSMED30027301h1SMcG0005090 dd_Smed_v4_5491_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
dorsal region of the epidermisSMED30027301h1SMcG0005090 dd_Smed_v4_5491_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Match: MYL1 (myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:7582])

HSP 1 Score: 70.0922 bits (170), Expect = 2.941e-14
Identity = 46/141 (32.62%), Postives = 73/141 (51.77%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELN-AIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            F+E F   D      I  SQ+G  LR  G  PT  ++ +++ N + E  +A+  K+E++ F  +M+  S  KD+       E    FDK+  G +  +ELR  LATLGE + E E+   M  G+  ++G + Y  F KH++
Sbjct:   11 FKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAK--KIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMA-GQEDSNGCINYEAFVKHIM 148          
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Match: CALML5 (calmodulin like 5 [Source:HGNC Symbol;Acc:HGNC:18180])

HSP 1 Score: 68.9366 bits (167), Expect = 7.130e-14
Identity = 43/154 (27.92%), Postives = 82/154 (53.25%), Query Frame = 1
Query:  202 AGETLTITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            AGE   +TP+E+  +++ F+++D      I A ++G AL+  G+  +E  + ++I  V  +     + ++ + +F    K+     ++L      AF  FD+   G I   ELR+A+A LG+ L + E++  +++  V  DGR+ Y +FA+ L 
Sbjct:    2 AGE---LTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDG----DGEISFQEFLTAAKKARAGLEDLQV----AFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARMLA 144          
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Match: MYL1 (myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:7582])

HSP 1 Score: 69.707 bits (169), Expect = 8.131e-14
Identity = 46/141 (32.62%), Postives = 73/141 (51.77%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELN-AIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            F+E F   D      I  SQ+G  LR  G  PT  ++ +++ N + E  +A+  K+E++ F  +M+  S  KD+       E    FDK+  G +  +ELR  LATLGE + E E+   M  G+  ++G + Y  F KH++
Sbjct:   55 FKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAK--KIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMA-GQEDSNGCINYEAFVKHIM 192          
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Match: CALM2 (calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445])

HSP 1 Score: 67.0106 bits (162), Expect = 3.373e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Match: CALM2 (calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445])

HSP 1 Score: 67.0106 bits (162), Expect = 3.373e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 77.411 bits (189), Expect = 2.503e-17
Identity = 49/147 (33.33%), Postives = 76/147 (51.70%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHL 660
            +TP+E   FRE F   D      I   ++G A+R  GQ PTE++I E+I  V  +       ++E+ +F  +MK+  K  D  + +I EAF  FDK   G+I   E R  +  +G    E E++E +K+  V  DG + Y +F K +
Sbjct:   18 LTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGN----GQIEFPEFCVMMKRMMKETD--SEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMM 158          
BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Match: cal-1 (Calmodulin-like protein [Source:UniProtKB/Swiss-Prot;Acc:P04630])

HSP 1 Score: 77.7962 bits (190), Expect = 3.364e-17
Identity = 49/147 (33.33%), Postives = 76/147 (51.70%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHL 660
            +TP+E   FRE F   D      I   ++G A+R  GQ PTE++I E+I  V  +       ++E+ +F  +MK+  K  D  + +I EAF  FDK   G+I   E R  +  +G    E E++E +K+  V  DG + Y +F K +
Sbjct:   37 LTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGN----GQIEFPEFCVMMKRMMKETD--SEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMM 177          
BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Match: cmd-1 (Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O16305])

HSP 1 Score: 67.0106 bits (162), Expect = 1.299e-13
Identity = 41/148 (27.70%), Postives = 74/148 (50.00%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F   + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Match: mlc-5 (Myosin-2 essential light chain [Source:UniProtKB/Swiss-Prot;Acc:Q9XVI9])

HSP 1 Score: 66.2402 bits (160), Expect = 2.578e-13
Identity = 43/142 (30.28%), Postives = 72/142 (50.70%), Query Frame = 1
Query:  247 RETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAI-IDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDS 669
            RE F   D+   + I   Q+G  LR  GQ PTE +I + + +   E      A+L ++DF  I +  SK +++       E    FDK+  G+I  +ELR  L TLGE L + ++++ +  G   + G +   DF + +++S
Sbjct:    8 REVFAYFDSKGDERISVQQVGDVLRALGQNPTEAEIHKCVGSFDRE------ARLSFEDFVPIFQSVSKNREKHTVEEFVEGLSHFDKEGNGMINVAELRHLLTTLGERLSDEDVDQLLS-GHNDSHGNVNISDFVRAVMNS 142          
BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Match: mlc-5 (Myosin-2 essential light chain [Source:UniProtKB/Swiss-Prot;Acc:Q9XVI9])

HSP 1 Score: 66.2402 bits (160), Expect = 2.578e-13
Identity = 43/142 (30.28%), Postives = 72/142 (50.70%), Query Frame = 1
Query:  247 RETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAI-IDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDS 669
            RE F   D+   + I   Q+G  LR  GQ PTE +I + + +   E      A+L ++DF  I +  SK +++       E    FDK+  G+I  +ELR  L TLGE L + ++++ +  G   + G +   DF + +++S
Sbjct:    8 REVFAYFDSKGDERISVQQVGDVLRALGQNPTEAEIHKCVGSFDRE------ARLSFEDFVPIFQSVSKNREKHTVEEFVEGLSHFDKEGNGMINVAELRHLLTTLGERLSDEDVDQLLS-GHNDSHGNVNISDFVRAVMNS 142          
BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304964)

HSP 1 Score: 67.0106 bits (162), Expect = 1.632e-13
Identity = 41/148 (27.70%), Postives = 74/148 (50.00%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F   + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0088001)

HSP 1 Score: 67.0106 bits (162), Expect = 1.632e-13
Identity = 41/148 (27.70%), Postives = 74/148 (50.00%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F   + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0304963)

HSP 1 Score: 67.0106 bits (162), Expect = 1.632e-13
Identity = 41/148 (27.70%), Postives = 74/148 (50.00%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F   + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0088002)

HSP 1 Score: 67.0106 bits (162), Expect = 1.632e-13
Identity = 41/148 (27.70%), Postives = 74/148 (50.00%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F   + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Match: Cam (gene:FBgn0000253 transcript:FBtr0345018)

HSP 1 Score: 67.0106 bits (162), Expect = 1.632e-13
Identity = 41/148 (27.70%), Postives = 74/148 (50.00%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F   + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Match: calm2a (calmodulin 2a (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030804-3])

HSP 1 Score: 67.0106 bits (162), Expect = 2.103e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Match: calm3a (calmodulin 3a (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-5590])

HSP 1 Score: 67.0106 bits (162), Expect = 2.145e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Match: calm3b (calmodulin 3b (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-527])

HSP 1 Score: 67.0106 bits (162), Expect = 2.145e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Match: calm1b (calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2])

HSP 1 Score: 67.0106 bits (162), Expect = 2.145e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Match: calm1b (calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2])

HSP 1 Score: 67.0106 bits (162), Expect = 2.145e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Match: calml4 (calmodulin like 4 [Source:NCBI gene;Acc:496530])

HSP 1 Score: 71.633 bits (174), Expect = 5.914e-15
Identity = 43/144 (29.86%), Postives = 73/144 (50.69%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDSYP 675
            F+E F+  D   +  IPA  +   +R  G CPT  ++   +Q     ++  ++ ++++  F  IM +  K +D  N I+  A L  DK+  G+I   ELR  L  +GE L   E+++ +K  KVG DG + Y +F + +    P
Sbjct:   10 FKECFSLYDKKGKGKIPAGDLLTVMRCLGTCPTPGEVTRHLQV----HKIGKDGEVDFSTFLTIMYRQQKQEDPENEIM-VAMLMSDKQKKGVIPLKELRAKLTQMGEKLTPEEVDDLLKGVKVGPDGMVKYEEFVRQITLPVP 148          
BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Match: calml4 (calmodulin like 4 [Source:NCBI gene;Acc:496530])

HSP 1 Score: 71.633 bits (174), Expect = 7.004e-15
Identity = 43/144 (29.86%), Postives = 73/144 (50.69%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDSYP 675
            F+E F+  D   +  IPA  +   +R  G CPT  ++   +Q     ++  ++ ++++  F  IM +  K +D  N I+  A L  DK+  G+I   ELR  L  +GE L   E+++ +K  KVG DG + Y +F + +    P
Sbjct:   13 FKECFSLYDKKGKGKIPAGDLLTVMRCLGTCPTPGEVTRHLQV----HKIGKDGEVDFSTFLTIMYRQQKQEDPENEIM-VAMLMSDKQKKGVIPLKELRAKLTQMGEKLTPEEVDDLLKGVKVGPDGMVKYEEFVRQITLPVP 151          
BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Match: myl1 (myosin light chain 1 [Source:NCBI gene;Acc:394551])

HSP 1 Score: 68.1662 bits (165), Expect = 1.466e-13
Identity = 46/150 (30.67%), Postives = 81/150 (54.00%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIID--EAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            I  +E+  F+E F   D      I  +Q+   +R  GQ PT  ++++++ N + E  +A+  K+E++ F  +M+  +  KD+  +  D  E    FDK+  G +  +ELR  LATLGE + E E+ E +  G+  ++G + Y  F KH++
Sbjct:    4 IPNEEELYFKEAFLLFDRTGDSKIALNQVADVMRALGQNPTNAEVKKVLGNPSAEEMNAK--KIEFEQFLPMMQAVANNKDQ-GSFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMREEEV-EALLAGQEDSNGCINYEAFVKHIM 149          
BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 67.781 bits (164), Expect = 1.566e-13
Identity = 40/141 (28.37%), Postives = 72/141 (51.06%), Query Frame = 1
Query:  241 VFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    1 MFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 136          
BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Match: CALM2 (calmodulin 1 (phosphorylase kinase, delta) [Source:NCBI gene;Acc:100496298])

HSP 1 Score: 67.781 bits (164), Expect = 1.612e-13
Identity = 40/142 (28.17%), Postives = 72/142 (50.70%), Query Frame = 1
Query:  238 KVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            + F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    4 QTFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 140          
BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Match: Myl1 (myosin, light polypeptide 1 [Source:MGI Symbol;Acc:MGI:97269])

HSP 1 Score: 68.1662 bits (165), Expect = 8.267e-14
Identity = 46/141 (32.62%), Postives = 75/141 (53.19%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELN-AIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            F+E F   D      I  SQ+G  LR  G  PT  ++++++ N + E  +A+  K+E++ F  +M+  S  KD+       E    FDK+  G +  +ELR  LATLGE + E E+ E +  G+  ++G + Y  F KH++
Sbjct:   11 FKEAFLLFDRTGECKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAK--KIEFEQFLPMMQAISNNKDQGGYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEV-EALLAGQEDSNGCINYEAFVKHIM 148          
BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Match: Myl1 (myosin, light polypeptide 1 [Source:MGI Symbol;Acc:MGI:97269])

HSP 1 Score: 68.9366 bits (167), Expect = 9.318e-14
Identity = 49/146 (33.56%), Postives = 78/146 (53.42%), Query Frame = 1
Query:  229 QEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELN-AIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            QED  F+E F   D      I  SQ+G  LR  G  PT  ++++++ N + E  +A+  K+E++ F  +M+  S  KD+       E    FDK+  G +  +ELR  LATLGE + E E+ E +  G+  ++G + Y  F KH++
Sbjct:   46 QED--FKEAFLLFDRTGECKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEMNAK--KIEFEQFLPMMQAISNNKDQGGYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEV-EALLAGQEDSNGCINYEAFVKHIM 186          
BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Match: Calm3 (calmodulin 3 [Source:MGI Symbol;Acc:MGI:103249])

HSP 1 Score: 67.0106 bits (162), Expect = 2.315e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Match: Calm1 (calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251])

HSP 1 Score: 67.0106 bits (162), Expect = 2.315e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Match: Calm2 (calmodulin 2 [Source:MGI Symbol;Acc:MGI:103250])

HSP 1 Score: 67.0106 bits (162), Expect = 2.315e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Match: sp|P04630|CALL_CAEEL (Calmodulin-like protein OS=Caenorhabditis elegans OX=6239 GN=cal-1 PE=3 SV=1)

HSP 1 Score: 77.411 bits (189), Expect = 3.183e-16
Identity = 49/147 (33.33%), Postives = 76/147 (51.70%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHL 660
            +TP+E   FRE F   D      I   ++G A+R  GQ PTE++I E+I  V  +       ++E+ +F  +MK+  K  D  + +I EAF  FDK   G+I   E R  +  +G    E E++E +K+  V  DG + Y +F K +
Sbjct:   18 LTPEEIDEFREAFMMFDKDGNGTISTKELGIAMRSLGQNPTEQEILEMINEVDIDGN----GQIEFPEFCVMMKRMMKETD--SEMIREAFRVFDKDGNGVITAQEFRYFMVHMGMQFSEEEVDEMIKEVDVDGDGEIDYEEFVKMM 158          
BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Match: sp|Q2R1Z5|CML6_ORYSJ (Putative calmodulin-like protein 6 OS=Oryza sativa subsp. japonica OX=39947 GN=CML6 PE=3 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 3.266e-15
Identity = 45/145 (31.03%), Postives = 78/145 (53.79%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQ--YSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDSY 672
            FR+ F+  D  N   I   ++   L   G  P+++D++++I  V E+        +E+D+F AIMK+  Y   K +    + +AF  FDK D G I  +EL   +A+LGE + E EI++ MK      DG++ Y +F + ++ ++
Sbjct:   13 FRDAFSLFDKNNDGCISREELATVLTRLGMAPSQEDLQDMIVAVDEDGNGT----IEFDEFLAIMKKKLYENDKGDDEEELRKAFRIFDKDDNGFISRNELSMVMASLGEEMTEDEIDDMMKAADSNNDGQVDYEEFKRVMMSTW 153          
BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Match: sp|P07463|CALM_PARTE (Calmodulin OS=Paramecium tetraurelia OX=5888 GN=CAM PE=1 SV=3)

HSP 1 Score: 72.7886 bits (177), Expect = 1.186e-14
Identity = 42/148 (28.38%), Postives = 78/148 (52.70%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F   D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F ++M +  K +D    +I EAF  FD+   GLI  +ELR  +  LGE L + E++E +++  +  DG + Y +F + +V
Sbjct:    5 LTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLSLMARKMKEQDSEEELI-EAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINYEEFVRMMV 147          
BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Match: sp|Q8S1Y9|CML1_ORYSJ (Calmodulin-like protein 1 OS=Oryza sativa subsp. japonica OX=39947 GN=CML1 PE=2 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 2.147e-14
Identity = 46/146 (31.51%), Postives = 75/146 (51.37%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNV-TEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDSYPR 678
            FRE F+  D      I   ++G  +R  GQ PTE +++++I  V T+ N       +E+ +F  +M +  + KD    +  EAF  FDK   G I  +ELR  +A +GE L + E+ E + +  V  DG++ Y +F K ++    R
Sbjct:   13 FREAFSLFDKDGDGSITTKELGTVMRSLGQNPTEAELQDMISEVDTDSN-----GNIEFKEFLGLMARKLRDKDSEEEL-KEAFRVFDKDQNGFISATELRHVMANIGERLTDEEVGEMISEADVDGDGQINYEEFVKCMMAKKRR 152          
BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Match: sp|Q40642|CML1_ORYSI (Calmodulin-like protein 1 OS=Oryza sativa subsp. indica OX=39946 GN=CML1 PE=1 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 2.259e-14
Identity = 44/145 (30.34%), Postives = 74/145 (51.03%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDSYPR 678
            FRE F+  D      I   ++G  +R  GQ PTE +++++I  V  ++       +E+ +F  +M +  + KD    +  EAF  FDK   G I  +ELR  +A +GE L + E+ E + +  V  DG++ Y +F K ++    R
Sbjct:   13 FREAFSLFDKDGDGSITTKELGTVMRSLGQNPTEAELQDMISEVDADSN----GNIEFKEFLGLMARKLRDKDSEEEL-KEAFRVFDKDQNGFISAAELRHVMANIGERLTDEEVGEMISEADVDGDGQINYEEFVKCMMAKKRR 152          
BLAST of Troponin C, skeletal muscle vs. TrEMBL
Match: A0A267F0S6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023662g1 PE=4 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 2.238e-36
Identity = 74/167 (44.31%), Postives = 113/167 (67.66%), Query Frame = 1
Query:  190 EQDEAGETLTITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQ--SAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGT-DGRLPYGDFAKHLVDSYPRP 681
            E+  A E L +TPQE+K+FRET+N++ +  R  +P + IG ALR+N QCPTE ++++II++  +E+     E  K+++++F  IMK+  KT+D+L   +  AF TFDK + G+IE  + +  + TLGE L+E EINE +KD   GT DG++PY  F  HL+D+Y RP
Sbjct:    5 EEGNAEEVLELTPQEEKLFRETYNAL-SKGRGDLPVNLIGQALRMNNQCPTEAELQKIIEDHRDEDAVDPDEMPKVDFEEFCTIMKENWKTRDQLEDQLKAAFATFDKAESGIIEAEDFKNWMMTLGEALEEGEINELLKDA--GTLDGKVPYDQFVPHLLDAYGRP 168          
BLAST of Troponin C, skeletal muscle vs. TrEMBL
Match: A0A1I8JK41 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023662g3 PE=4 SV=1)

HSP 1 Score: 135.576 bits (340), Expect = 1.736e-35
Identity = 73/167 (43.71%), Postives = 113/167 (67.66%), Query Frame = 1
Query:  190 EQDEAGETLTITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQ--SAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGT-DGRLPYGDFAKHLVDSYPRP 681
            E+  A E L +T QE+K+FRET+N++ +  R  +P + IG ALR+N QCPTE ++++II++  +E+     E  K+++++F  IMK+  KT+D+L   +  AF TFDK + G+IE  + +  + TLGE+L+E EINE +KD   GT DG++PY  F  HL+D+Y RP
Sbjct:    5 EEGNAEEVLELTLQEEKLFRETYNAL-SKGRGDLPVNLIGQALRMNNQCPTEAELQKIIEDHRDEDAVDPDEMPKVDFEEFCTIMKENWKTRDQLEDQLKAAFATFDKAESGIIEAEDFKNWMMTLGEVLEEGEINELLKDA--GTLDGKVPYDQFVPHLLDAYGRP 168          
BLAST of Troponin C, skeletal muscle vs. TrEMBL
Match: A0A1I8GPT3 (Phospholipid-transporting ATPase OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 1.284e-30
Identity = 73/165 (44.24%), Postives = 105/165 (63.64%), Query Frame = 1
Query:  190 EQDEAGETLTITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGT-DGRLPYGDFAKHLVDSYPRP 681
            E+  A E L +TPQE+K+FRET+N++    R  +P + IG ALR+N QCPTE ++++II++  +E           D F  IMK+  KT+D+L   +  AF TFDK + G+IE  + +  + TLGE L+E EINE +KD   GT DG++PY  F  HL+D+Y RP
Sbjct: 1192 EEGNAEEVLELTPQEEKLFRETYNALSK-GRGDLPVNLIGQALRMNNQCPTEAELQKIIEDHRDE-----------DAFCTIMKENWKTRDQLEDQLKAAFATFDKAESGIIEAEDFKNWMMTLGEALEEGEINELLKDA--GTLDGKVPYDQFVPHLLDAYGRP 1342          
BLAST of Troponin C, skeletal muscle vs. TrEMBL
Match: A0A267DYY6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023662g2 PE=4 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 9.219e-28
Identity = 59/134 (44.03%), Postives = 91/134 (67.91%), Query Frame = 1
Query:  289 IPASQIGYALRINGQCPTEKDIEEIIQNVTEENQ--SAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGT-DGRLPYGDFAKHLVDSYPRP 681
            +P + IG ALR+N QCPTE ++++II++  +E+     E  K+++++F  IMK+  KT+D+L   +  AF TFDK + G+IE  + +  + TLGE+L+E EINE +KD   GT DG++PY  F  HL+D+Y RP
Sbjct:   36 LPVNLIGQALRMNNQCPTEAELQKIIEDHRDEDAVDPDEMPKVDFEEFCTIMKENWKTRDQLEDQLKAAFATFDKAESGIIEAEDFKNWMMTLGEVLEEGEINELLKDA--GTLDGKVPYDQFVPHLLDAYGRP 167          
BLAST of Troponin C, skeletal muscle vs. TrEMBL
Match: A0A4Z2DD75 (Troponin C, skeletal muscle isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_002204 PE=4 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 2.577e-24
Identity = 53/150 (35.33%), Postives = 85/150 (56.67%), Query Frame = 1
Query:  241 VFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSA---EEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDSYPRP 681
            V +  +NS+ +   + +  +QI   L++  QCPT+  + +I  + T E+      E   L  D F  I++ YS T+DE    ++ AFL FDK + G+++   ++  L T+G+   + E NEF K+   G+DG+ PY DF K LVD+YPRP
Sbjct:   28 VIKNIYNSLASAKSRKVTLNQICRCLQMLNQCPTQAVLNKIYSDYTPEDMEGIVPENIPLHLDQFTEIIQTYSYTRDERWNQLNNAFLFFDKNESGVVDTEPMKTMLLTVGDCFTDKECNEFFKEAAPGSDGKWPYDDFVKKLVDAYPRP 177          
BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Match: calm3a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 67.0106 bits (162), Expect = 1.818e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Match: calm2a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 67.0106 bits (162), Expect = 1.818e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Match: calm1b (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 67.0106 bits (162), Expect = 1.818e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Match: calm3a (calmodulin [Source:NCBI gene;Acc:103037741])

HSP 1 Score: 67.0106 bits (162), Expect = 1.818e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Match: calm3b (calmodulin 3b (phosphorylase kinase, delta) [Source:ZFIN;Acc:ZDB-GENE-030131-527])

HSP 1 Score: 67.0106 bits (162), Expect = 2.203e-13
Identity = 40/140 (28.57%), Postives = 71/140 (50.71%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:   13 FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Match: CALML3 (calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:1452])

HSP 1 Score: 67.0106 bits (162), Expect = 3.615e-14
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Match: CALM3 (calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449])

HSP 1 Score: 67.0106 bits (162), Expect = 3.688e-14
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Match: si:rp71-17i16.4 (si:rp71-17i16.4 [Source:ZFIN;Acc:ZDB-GENE-090312-215])

HSP 1 Score: 67.3958 bits (163), Expect = 3.848e-14
Identity = 44/145 (30.34%), Postives = 76/145 (52.41%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSK------TKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHL 660
            F+  F+  DA     I  S++G  +++ GQ PT+++++ II+ V E+        +++++F  +M +  K      T++EL     EAF   D    G I+  EL+  L   GE + + E++E MKDG    DGRL + +F K +
Sbjct:   25 FKAAFDMFDADGGGDISTSELGKVMKLLGQTPTKEELDAIIEEVDEDGSGT----IDFEEFLVMMVRQMKEESAGQTEEELA----EAFRILDTNGDGYIDRDELKDILLNTGENVTDLEMDELMKDGDKNCDGRLDFDEFLKMM 161          
BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006008.1 (pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-1 gene:ENSPMAG00000005430.1 transcript:ENSPMAT00000006008.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 67.0106 bits (162), Expect = 3.879e-14
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITVKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Match: cmlc1 (cardiac myosin light chain-1 [Source:ZFIN;Acc:ZDB-GENE-030522-1])

HSP 1 Score: 66.6254 bits (161), Expect = 6.507e-14
Identity = 46/141 (32.62%), Postives = 71/141 (50.35%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELN-AIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +RE F+  D      I  SQ G  +R  GQ PT  D+ +++ N   E    +   +++D F  +M+   K KD+ +     E    FDK+  G +  +ELR  LATLGE L E E+ + M  G+  + G + Y  F KH++
Sbjct:   12 YREAFSLFDRTGEMKITYSQCGDIMRALGQNPTNCDVMKVLGNPKPEEMLVK--TMDFDTFLPMMQAICKIKDQGSYEDFVEGLRVFDKEGNGRVMGAELRHVLATLGERLTEDEVEQLMT-GQEDSSGCINYEAFIKHIL 149          
BLAST of Troponin C, skeletal muscle vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 62.3882 bits (150), Expect = 1.020e-12
Identity = 39/147 (26.53%), Postives = 77/147 (52.38%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHL 660
            +T ++   F+E F   D  N   I +S++   +R  G  P+E ++ +++  +  +       ++E+ +F A+M +  K+ D    ++ EAF  FDK   GLI  +EL+  L ++GE L + E+++ +++   G+ G +    FA  L
Sbjct:    5 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNH----QIEFSEFLALMSRQLKSNDSEQELL-EAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREVSDGS-GEINIQQFAALL 145          
BLAST of Troponin C, skeletal muscle vs. Ensembl Yeast
Match: MLC1 (Essential light chain for Myo1p; light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition [Source:SGD;Acc:S000003074])

HSP 1 Score: 46.595 bits (109), Expect = 5.101e-7
Identity = 37/144 (25.69%), Postives = 65/144 (45.14%), Query Frame = 1
Query:  247 RETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAK-LEYDDFKAIMKQYSKTKDELNAIIDE----AFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            ++ F   D   +  I    +G  LR  G  PT     +++Q++   + S  +A  L  D    +++   K  D       E    AF  FDK+  G +   +LR  L  LGE L + E++E +K  +V ++G + Y  F + ++
Sbjct:    8 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTN----QLVQDIINADSSLRDASSLTLDQITGLIEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFIEDVL 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Match: EDO46606 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPN8])

HSP 1 Score: 70.0922 bits (170), Expect = 4.432e-15
Identity = 41/140 (29.29%), Postives = 71/140 (50.71%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F K + 
Sbjct:    4 FKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKNTDSEEEI-REAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYDEFVKMMT 138          
BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Match: EDO46518 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPI8])

HSP 1 Score: 69.3218 bits (168), Expect = 1.141e-14
Identity = 42/148 (28.38%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F K + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVKMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Match: EDO33580 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRU7])

HSP 1 Score: 68.5514 bits (166), Expect = 2.286e-14
Identity = 47/151 (31.13%), Postives = 81/151 (53.64%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTK---DELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T +E   ++E F+  D      +  +++G  +R  GQ PT+++I E+I+ V E+   +    + +++F  +M + +K K   DEL A    AF  FDK   G I  +EL++ L +LGE L E E+ E +K+     DG +   +F K +V
Sbjct:    5 LTEEEIAEYKEAFSLFDKDGDGTVTTAELGTVMRNLGQNPTDEEIREMIKEVDEDGSGS----IGFEEFLQLMSKKTKGKSYEDELMA----AFQIFDKDGNGSITVTELKEVLDSLGEKLSEDEVGEMIKEADSDGDGTVNIEEFIKMMV 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Match: EDO30674 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T043])

HSP 1 Score: 68.9366 bits (167), Expect = 2.607e-14
Identity = 41/154 (26.62%), Postives = 84/154 (54.55%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDSYPRP 681
            +T ++    +E F+  D      I   ++   ++  GQ P++++++++IQ V  +       ++++++F A+MK+  + +D   A + EAF  FD+   G I E ELR  +A+LGE L + EI E M++  +  DG + + +F + + +   +P
Sbjct:   13 LTAEQRNELQEAFSLFDKDGSGTISNEELEVVMKSLGQNPSDEELQQMIQEVDADGN----GEVDFEEFLAMMKKQMQHRD-AEAEMREAFRVFDRNGDGSISEWELRSVMASLGEKLSDDEIKEMMREADLDGDGVINFQEFVQMVREMDKQP 161          
BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Match: EDO30675 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T044])

HSP 1 Score: 62.3882 bits (150), Expect = 2.526e-12
Identity = 37/132 (28.03%), Postives = 72/132 (54.55%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPY 639
             +E F   D      I +S++ + +R  GQ PTE++++++I  V +++      ++++ +F  ++ +  K  D    I D AF  FDK   G+I  SEL+  ++ LGE L + E++E +++  +  DG + Y
Sbjct:    4 LKEAFALFDKDGGGSISSSELAHVMRSLGQNPTEQELKDMIAEVDQDDN----GEIDFPEFLQMVAKKIKETDTEEEIQD-AFKVFDKNGDGMISSSELKLVMSNLGERLTDDEVDEMIREADIDGDGMIDY 130          
BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Match: tnnc2 (troponin C, skeletal muscle [Source:NCBI gene;Acc:101171829])

HSP 1 Score: 69.707 bits (169), Expect = 2.257e-14
Identity = 44/145 (30.34%), Postives = 75/145 (51.72%), Query Frame = 1
Query:  244 FRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIM------KQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHL 660
            F+  F+  D      I   ++G  +R+ GQ PT ++++EII+ V E+        +++++F  +M       Q  K+++EL     E F  FDK   G+I+  E  + + + GE + E EI+E MKDG    DG L + +F K +
Sbjct:   20 FKAAFDMFDTDGGGDISTKELGTVMRMLGQNPTREELDEIIEEVDEDGSGT----IDFEEFLVMMVRLLKEDQAGKSEEELA----ECFRVFDKNGDGVIDREEFAQIIRSSGEPISEDEIDELMKDGDKNNDGMLDFDEFLKMM 156          
BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Match: mylz3 (myosin light chain 3, skeletal muscle isoform [Source:NCBI gene;Acc:101165624])

HSP 1 Score: 67.3958 bits (163), Expect = 1.350e-13
Identity = 44/148 (29.73%), Postives = 73/148 (49.32%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
             TP + + F+E F   D      +  +Q+   +R  GQ PT KD+ +I+ N T ++ + +  +L +D F  ++K+             E    FDK+  G +  +ELR  L+TLGE + E EI   M  G+   +G + Y  F KH++
Sbjct:    4 FTPDQIEDFKEAFGLFDRVGDSQVAFNQVADIMRALGQNPTNKDVAKILGNPTADDMANK--RLNFDAFLPMLKEVDALPKGTYDDYVEGLRVFDKEGNGTVMGAELRIVLSTLGEKMTEPEIEALMA-GQEDENGSVHYEAFVKHIM 148          
BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Match: calm2a (calmodulin 2 [Source:NCBI gene;Acc:100049420])

HSP 1 Score: 67.0106 bits (162), Expect = 1.807e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Match: ENSORLT00000008599.2 (calmodulin 3 [Source:NCBI gene;Acc:100049421])

HSP 1 Score: 67.0106 bits (162), Expect = 1.807e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Match: calm1b (calmodulin [Source:NCBI gene;Acc:100049419])

HSP 1 Score: 67.0106 bits (162), Expect = 1.807e-13
Identity = 41/148 (27.70%), Postives = 75/148 (50.68%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F + + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147          
BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Match: SMESG000053259.1 (SMESG000053259.1)

HSP 1 Score: 340.117 bits (871), Expect = 1.826e-119
Identity = 164/165 (99.39%), Postives = 164/165 (99.39%), Query Frame = 1
Query:  187 MEQDEAGETLTITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDSYPRP 681
            MEQDEAGETLTITPQEDKVFRETFNSID YNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDSYPRP
Sbjct:    1 MEQDEAGETLTITPQEDKVFRETFNSIDTYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLVDSYPRP 165          
BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Match: SMESG000029865.1 (SMESG000029865.1)

HSP 1 Score: 70.0922 bits (170), Expect = 1.485e-14
Identity = 46/125 (36.80%), Postives = 68/125 (54.40%), Query Frame = 1
Query:  250 ETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAE------EAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKD 606
            E F S D Y    +    +G  LR+  QCPTE   EEI +  TE  +S +      E ++ +D+F  I +   K++ E+++ +  AF  FD+K+ G    SEL+  L T+GE LD+ EI EFM D
Sbjct:   26 ELFKSFDKYEDGKVNIEHLGEMLRLLKQCPTE---EEIQKYTTEFIESIDTFTIQIEYRMTFDEFYTIYRMNYKSQFEISSDVVNAFKLFDRKNAGKFSASELKNLLETMGEHLDQDEILEFMDD 147          
BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Match: SMESG000034095.1 (SMESG000034095.1)

HSP 1 Score: 67.0106 bits (162), Expect = 1.362e-13
Identity = 41/148 (27.70%), Postives = 74/148 (50.00%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F   + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Match: SMESG000010769.1 (SMESG000010769.1)

HSP 1 Score: 67.0106 bits (162), Expect = 1.362e-13
Identity = 41/148 (27.70%), Postives = 74/148 (50.00%), Query Frame = 1
Query:  220 ITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            +T ++   F+E F+  D      I   ++G  +R  GQ PTE +++++I  V  +        +++ +F  +M +  K  D    I  EAF  FDK   G I  +ELR  +  LGE L + E++E +++  +  DG++ Y +F   + 
Sbjct:    5 LTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT----IDFPEFLTMMARKMKDTDSEEEI-REAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMT 147          
BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Match: SMESG000018137.1 (SMESG000018137.1)

HSP 1 Score: 62.003 bits (149), Expect = 1.161e-11
Identity = 42/138 (30.43%), Postives = 70/138 (50.72%), Query Frame = 1
Query:  250 ETFNSIDAYNRKWIPASQIGYALRINGQCPTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDEAFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLPYGDFAKHLV 663
            ++F   D  N   +  S+I   L+  GQ PT  D ++IIQ    +++     K+ + +F   +K+Y K    L   +  AFL FD  + G I + EL+  L +LG+ LD+ EI+E  +  +V  + R+ Y +F    V
Sbjct:   26 KSFCLFDQENTGSVQQSEIMAILQSLGQNPTPDDCDKIIQ----KSEKKSNQKITFLEFIRFVKEYIKDPGTLKDELKNAFLAFDTGNTGYISQQELKDILTSLGDRLDDDEIDEMFRLVEVDKEDRINYEEFINQFV 159          
The following BLAST results are available for this feature:
BLAST of Troponin C, skeletal muscle vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MYL12.941e-1432.62myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
CALML57.130e-1427.92calmodulin like 5 [Source:HGNC Symbol;Acc:HGNC:181... [more]
MYL18.131e-1432.62myosin light chain 1 [Source:HGNC Symbol;Acc:HGNC:... [more]
CALM23.373e-1327.70calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445][more]
CALM23.373e-1327.70calmodulin 2 [Source:HGNC Symbol;Acc:HGNC:1445][more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cal-12.503e-1733.33Calmodulin-like protein [Source:UniProtKB/Swiss-P... [more]
cal-13.364e-1733.33Calmodulin-like protein [Source:UniProtKB/Swiss-P... [more]
cmd-11.299e-1327.70Calmodulin [Source:UniProtKB/Swiss-Prot;Acc:O1630... [more]
mlc-52.578e-1330.28Myosin-2 essential light chain [Source:UniProtKB/... [more]
mlc-52.578e-1330.28Myosin-2 essential light chain [Source:UniProtKB/... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cam1.632e-1327.70gene:FBgn0000253 transcript:FBtr0304964[more]
Cam1.632e-1327.70gene:FBgn0000253 transcript:FBtr0088001[more]
Cam1.632e-1327.70gene:FBgn0000253 transcript:FBtr0304963[more]
Cam1.632e-1327.70gene:FBgn0000253 transcript:FBtr0088002[more]
Cam1.632e-1327.70gene:FBgn0000253 transcript:FBtr0345018[more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calm2a2.103e-1327.70calmodulin 2a (phosphorylase kinase, delta) [Sourc... [more]
calm3a2.145e-1327.70calmodulin 3a (phosphorylase kinase, delta) [Sourc... [more]
calm3b2.145e-1327.70calmodulin 3b (phosphorylase kinase, delta) [Sourc... [more]
calm1b2.145e-1327.70calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2][more]
calm1b2.145e-1327.70calmodulin 1b [Source:ZFIN;Acc:ZDB-GENE-030804-2][more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calml45.914e-1529.86calmodulin like 4 [Source:NCBI gene;Acc:496530][more]
calml47.004e-1529.86calmodulin like 4 [Source:NCBI gene;Acc:496530][more]
myl11.466e-1330.67myosin light chain 1 [Source:NCBI gene;Acc:394551][more]
CALM21.566e-1328.37calmodulin 1 (phosphorylase kinase, delta) [Source... [more]
CALM21.612e-1328.17calmodulin 1 (phosphorylase kinase, delta) [Source... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Myl18.267e-1432.62myosin, light polypeptide 1 [Source:MGI Symbol;Acc... [more]
Myl19.318e-1433.56myosin, light polypeptide 1 [Source:MGI Symbol;Acc... [more]
Calm32.315e-1327.70calmodulin 3 [Source:MGI Symbol;Acc:MGI:103249][more]
Calm12.315e-1327.70calmodulin 1 [Source:MGI Symbol;Acc:MGI:88251][more]
Calm22.315e-1327.70calmodulin 2 [Source:MGI Symbol;Acc:MGI:103250][more]
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BLAST of Troponin C, skeletal muscle vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P04630|CALL_CAEEL3.183e-1633.33Calmodulin-like protein OS=Caenorhabditis elegans ... [more]
sp|Q2R1Z5|CML6_ORYSJ3.266e-1531.03Putative calmodulin-like protein 6 OS=Oryza sativa... [more]
sp|P07463|CALM_PARTE1.186e-1428.38Calmodulin OS=Paramecium tetraurelia OX=5888 GN=CA... [more]
sp|Q8S1Y9|CML1_ORYSJ2.147e-1431.51Calmodulin-like protein 1 OS=Oryza sativa subsp. j... [more]
sp|Q40642|CML1_ORYSI2.259e-1430.34Calmodulin-like protein 1 OS=Oryza sativa subsp. i... [more]
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BLAST of Troponin C, skeletal muscle vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267F0S62.238e-3644.31Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8JK411.736e-3543.71Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8GPT31.284e-3044.24Phospholipid-transporting ATPase OS=Macrostomum li... [more]
A0A267DYY69.219e-2844.03Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A4Z2DD752.577e-2435.33Troponin C, skeletal muscle isoform 1 OS=Schistoso... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
calm3a1.818e-1327.70calmodulin [Source:NCBI gene;Acc:103037741][more]
calm2a1.818e-1327.70calmodulin [Source:NCBI gene;Acc:103037741][more]
calm1b1.818e-1327.70calmodulin [Source:NCBI gene;Acc:103037741][more]
calm3a1.818e-1327.70calmodulin [Source:NCBI gene;Acc:103037741][more]
calm3b2.203e-1328.57calmodulin 3b (phosphorylase kinase, delta) [Sourc... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CALML33.615e-1427.70calmodulin like 3 [Source:HGNC Symbol;Acc:HGNC:145... [more]
CALM33.688e-1427.70calmodulin 3 [Source:HGNC Symbol;Acc:HGNC:1449][more]
si:rp71-17i16.43.848e-1430.34si:rp71-17i16.4 [Source:ZFIN;Acc:ZDB-GENE-090312-2... [more]
ENSPMAT00000006008.13.879e-1427.70pep scaffold:Pmarinus_7.0:GL476713:142259:146509:-... [more]
cmlc16.507e-1432.62cardiac myosin light chain-1 [Source:ZFIN;Acc:ZDB-... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
CMD11.020e-1226.53Calmodulin; Ca2+ binding protein that regulates Ca... [more]
MLC15.101e-725.69Essential light chain for Myo1p; light chain for M... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO466064.432e-1529.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO465181.141e-1428.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO335802.286e-1431.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO306742.607e-1426.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO306752.526e-1228.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Troponin C, skeletal muscle vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tnnc22.257e-1430.34troponin C, skeletal muscle [Source:NCBI gene;Acc:... [more]
mylz31.350e-1329.73myosin light chain 3, skeletal muscle isoform [Sou... [more]
calm2a1.807e-1327.70calmodulin 2 [Source:NCBI gene;Acc:100049420][more]
ENSORLT00000008599.21.807e-1327.70calmodulin 3 [Source:NCBI gene;Acc:100049421][more]
calm1b1.807e-1327.70calmodulin [Source:NCBI gene;Acc:100049419][more]
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BLAST of Troponin C, skeletal muscle vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053259.11.826e-11999.39SMESG000053259.1[more]
SMESG000029865.11.485e-1436.80SMESG000029865.1[more]
SMESG000034095.11.362e-1327.70SMESG000034095.1[more]
SMESG000010769.11.362e-1327.70SMESG000010769.1[more]
SMESG000018137.11.161e-1130.43SMESG000018137.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027301 ID=SMED30027301|Name=Troponin C, skeletal muscle|organism=Schmidtea mediterranea sexual|type=transcript|length=835bp
CGCGATTACATTTTTCAAACAATAGTCAAAGAATAATTGTATTTACCTTG
ACAACAATTATAATAGGTTATCAAACACACATGCACAAGCACACACACAA
TCACTGACACACATTCTCGCTCTGAATTCAAACGATAAAGTTATATTAAT
TGTATTGGTATTAAAAATTTTCAAAATTAATTCAACATGGAACAAGACGA
GGCAGGCGAAACTCTGACCATCACACCACAGGAAGATAAAGTTTTTCGAG
AGACTTTTAATTCTATTGATGCATATAATCGAAAATGGATTCCGGCGTCC
CAAATTGGTTATGCTTTAAGAATTAATGGTCAGTGCCCTACAGAAAAAGA
TATCGAAGAAATTATTCAAAATGTGACGGAGGAGAACCAATCTGCAGAGG
AAGCCAAGCTGGAATATGACGACTTCAAGGCAATTATGAAACAATATTCC
AAAACAAAAGATGAACTGAATGCAATAATTGATGAAGCTTTTCTTACATT
TGATAAAAAGGATTGTGGACTTATAGAAGAATCCGAATTAAGAAAAGCTC
TGGCAACTTTAGGTGAAATATTAGACGAAACAGAAATCAATGAGTTTATG
AAAGATGGGAAAGTTGGAACAGATGGTCGACTTCCTTATGGGGATTTTGC
TAAACATCTTGTTGATTCATATCCACGACCTGGAAGTAAAAAGAAAGGTT
CGGGTAAAAAAGGAGCATCTGCTGCAAGTAAAAAATCTAAAAAGAAATAA
AATTCTATTTCAGATTTTGATTAAAAGGATTTATTTTTGTTAATTATATT
TTGTGTAATAATTTGAAAATAAAAAATAATTAGAA
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protein sequence of SMED30027301-orf-1

>SMED30027301-orf-1 ID=SMED30027301-orf-1|Name=SMED30027301-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=188bp
MEQDEAGETLTITPQEDKVFRETFNSIDAYNRKWIPASQIGYALRINGQC
PTEKDIEEIIQNVTEENQSAEEAKLEYDDFKAIMKQYSKTKDELNAIIDE
AFLTFDKKDCGLIEESELRKALATLGEILDETEINEFMKDGKVGTDGRLP
YGDFAKHLVDSYPRPGSKKKGSGKKGASAASKKSKKK*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000034epidermis
PLANA:0000054dorsal region of the epidermis
PLANA:0000096ventral epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR011992EF-hand-dom_pair
IPR002048EF_hand_dom
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 53..90
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 10..92
e-value: 6.8E-12
score: 47.5
NoneNo IPR availableGENE3DG3DSA:1.10.238.10coord: 93..183
e-value: 2.3E-11
score: 45.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 168..187
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 161..187
NoneNo IPR availablePANTHERPTHR23048MYOSIN LIGHT CHAIN 1, 3coord: 15..159
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 15..50
score: 5.643
IPR002048EF-hand domainPROSITEPS50222EF_HAND_2coord: 93..128
score: 10.05
IPR011992EF-hand domain pairSUPERFAMILYSSF47473EF-handcoord: 13..158