SMED30027296

Overview
NameSMED30027296
Smed IDSMED30027296
Length (bp)1358
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SMED30027296 (SMED30027296) t-SNE clustered cells

Violin plots show distribution of expression levels for SMED30027296 (SMED30027296) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SMED30027296 (SMED30027296) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SMED30027296 (SMED30027296) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30027296

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30027296h1SMcG0012128 Contig5043GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30027296h1SMcG0012128 Contig3785GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30027296h1SMcG0012129 Contig5043GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Smed sexual biotypeSMED30027296h1SMcG0012128 Contig3785GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30027296h1SMcG0012128 dd_Smed_v4_994_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30027296h1SMcG0012128 dd_Smed_v4_994_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30027296h1SMcG0012128 dd_Smed_v4_994_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027296h1SMcG0012128 Contig39551uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30027296h1SMcG0012128 Contig39551newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30027296h1SMcG0012128 SMED30027296smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30027296h1SMcG0012128 SMED30027296smed_20140614PMID:26457503
Tu et al., 2015		whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30027296h1SMcG0012128 dd_Smed_v6_994_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
glial cellSMED30027296h1SMcG0012128 dd_Smed_v6_994_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30027296 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.009378:12883..16343 +6636
Homology
[Close]
BLAST of SMED30027296 vs. Ensembl Human
Match: PANK4 (pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366])

HSP 1 Score: 70.8626 bits (172), Expect = 2.237e-12
Identity = 82/306 (26.80%), Postives = 132/306 (43.14%), Query Frame = 2 
Query:  362 FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            F N+  +  L ++KD     E K   I  TG G  K+ + I+E L   V   D      +G  ++L N+P     Y +              +D + +F+              + P +   IGSG     + ++  F  V G    G TF GL   +  T  ++E++ +ASRG   NVD+ V+D+ G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  ++H+   V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:   96 FENTYIEACLDFIKDHLVNTETK--VIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKD-------------SDPEFRFQT---------NHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQ---EFSKEDMAKSLLHM-ISNDIGQL--ACLHARLHSLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 366
[Close]
BLAST of SMED30027296 vs. Ensembl Human
Match: PANK4 (pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366])

HSP 1 Score: 70.8626 bits (172), Expect = 2.237e-12
Identity = 82/306 (26.80%), Postives = 132/306 (43.14%), Query Frame = 2 
Query:  362 FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            F N+  +  L ++KD     E K   I  TG G  K+ + I+E L   V   D      +G  ++L N+P     Y +              +D + +F+              + P +   IGSG     + ++  F  V G    G TF GL   +  T  ++E++ +ASRG   NVD+ V+D+ G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  ++H+   V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:   96 FENTYIEACLDFIKDHLVNTETK--VIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKD-------------SDPEFRFQT---------NHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQ---EFSKEDMAKSLLHM-ISNDIGQL--ACLHARLHSLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 366
[Close]
BLAST of SMED30027296 vs. Ensembl Human
Match: PANK4 (pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366])

HSP 1 Score: 70.8626 bits (172), Expect = 2.391e-12
Identity = 82/306 (26.80%), Postives = 132/306 (43.14%), Query Frame = 2 
Query:  362 FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            F N+  +  L ++KD     E K   I  TG G  K+ + I+E L   V   D      +G  ++L N+P     Y +              +D + +F+              + P +   IGSG     + ++  F  V G    G TF GL   +  T  ++E++ +ASRG   NVD+ V+D+ G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  ++H+   V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:  104 FENTYIEACLDFIKDHLVNTETK--VIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKD-------------SDPEFRFQT---------NHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQ---EFSKEDMAKSLLHM-ISNDIGQL--ACLHARLHSLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 374
[Close]
BLAST of SMED30027296 vs. Ensembl Human
Match: PANK4 (pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366])

HSP 1 Score: 67.0106 bits (162), Expect = 2.543e-11
Identity = 53/169 (31.36%), Postives = 82/169 (48.52%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            F  V G    G TF GL   +  T  ++E++ +ASRG   NVD+ V+D+ G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  ++H+   V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:   67 FEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQ---EFSKEDMAKSLLHM-ISNDIGQL--ACLHARLHSLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 224
[Close]
BLAST of SMED30027296 vs. Ensembl Human
Match: PANK4 (pantothenate kinase 4 (inactive) [Source:HGNC Symbol;Acc:HGNC:19366])

HSP 1 Score: 67.0106 bits (162), Expect = 2.543e-11
Identity = 53/169 (31.36%), Postives = 82/169 (48.52%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            F  V G    G TF GL   +  T  ++E++ +ASRG   NVD+ V+D+ G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  ++H+   V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:   67 FEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQ---EFSKEDMAKSLLHM-ISNDIGQL--ACLHARLHSLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 224
[Close]
BLAST of SMED30027296 vs. Ensembl Celegans
Match: pnk-1 (PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:H2KYP7])

HSP 1 Score: 66.6254 bits (161), Expect = 1.085e-11
Identity = 77/284 (27.11%), Postives = 125/284 (44.01%), Query Frame = 2 
Query:  440 IHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLL-PCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAE-------TKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            IH TG G  KYSE I + L   +   DE  S   G  ++L+       TY               I   K Q+  I           DL+ P +   IG+G     + S  ++  V G    G TF+GL   +    +++E++EMA+RGD RNVD  V DI G  ++++L  +  +I  G +A+       TKK   +   +D+A SL+ M   N    A        +  ++FGG        R++  T++ + F++N+ +       Y    G+ GA+G+ +
Sbjct:  141 IHCTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHH-----------DAIGRNKFQYRPIAA---------DLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGG-AYDELGLKADLI-AGSMAKCNRFEETTKKQ--QHKPEDIAKSLLLMVSNNIGQMAYLYGTRYNLKRIYFGGYF-----IRQDPITMRTLSFAINYWSKGEIEALYLKHEGYLGAMGSFL 395
[Close]
BLAST of SMED30027296 vs. Ensembl Celegans
Match: pnk-1 (PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:H2KYP7])

HSP 1 Score: 66.6254 bits (161), Expect = 1.085e-11
Identity = 77/284 (27.11%), Postives = 125/284 (44.01%), Query Frame = 2 
Query:  440 IHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLL-PCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAE-------TKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            IH TG G  KYSE I + L   +   DE  S   G  ++L+       TY               I   K Q+  I           DL+ P +   IG+G     + S  ++  V G    G TF+GL   +    +++E++EMA+RGD RNVD  V DI G  ++++L  +  +I  G +A+       TKK   +   +D+A SL+ M   N    A        +  ++FGG        R++  T++ + F++N+ +       Y    G+ GA+G+ +
Sbjct:  141 IHCTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHH-----------DAIGRNKFQYRPIAA---------DLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGG-AYDELGLKADLI-AGSMAKCNRFEETTKKQ--QHKPEDIAKSLLLMVSNNIGQMAYLYGTRYNLKRIYFGGYF-----IRQDPITMRTLSFAINYWSKGEIEALYLKHEGYLGAMGSFL 395
[Close]
BLAST of SMED30027296 vs. Ensembl Celegans
Match: pnk-1 (PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:H2KYP7])

HSP 1 Score: 66.2402 bits (160), Expect = 1.824e-11
Identity = 77/284 (27.11%), Postives = 125/284 (44.01%), Query Frame = 2 
Query:  440 IHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLL-PCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAE-------TKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            IH TG G  KYSE I + L   +   DE  S   G  ++L+       TY               I   K Q+  I           DL+ P +   IG+G     + S  ++  V G    G TF+GL   +    +++E++EMA+RGD RNVD  V DI G  ++++L  +  +I  G +A+       TKK   +   +D+A SL+ M   N    A        +  ++FGG        R++  T++ + F++N+ +       Y    G+ GA+G+ +
Sbjct:  187 IHCTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLSTNVDESFTYHHDA-----------IGRNKFQYRPIAA---------DLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGG-AYDELGLKADLI-AGSMAKCNRFEETTKKQ--QHKPEDIAKSLLLMVSNNIGQMAYLYGTRYNLKRIYFGGYF-----IRQDPITMRTLSFAINYWSKGEIEALYLKHEGYLGAMGSFL 441
[Close]
BLAST of SMED30027296 vs. Ensembl Celegans
Match: pnk-4 (Pantothenate kinase [Source:UniProtKB/TrEMBL;Acc:Q18580])

HSP 1 Score: 56.9954 bits (136), Expect = 2.137e-8
Identity = 64/275 (23.27%), Postives = 118/275 (42.91%), Query Frame = 2 
Query:  446 LTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFE-KLSPELPIIHMGKL--AETKKSITEFN---KDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSE-VFRKEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            +T +   +  E I+++LD ++  VD F     G  ++L N+     TY+             F    + +F+ +          + + P +   I +G     +  +  F+ + G    G +F+GL+  I G +D  E+M+ A +G     D+ ++DI GD +    + P L     G++   ET +    F+   K++   SL+ M +YN    A  +     V  VFF G L ++  +  K  S     +S   +  YF+ +  +T  LGA +
Sbjct:   94 VTASQNAEIEEVIRKVLDVELRHVDAFNGLVNGTSFLLRNIEAECFTYS-------------FDESQEYEFQTL--------NNDSMFPYLLINIRTGVSVVLVEGENQFKRLGGSSIGGGSFLGLTELITGVSDIEEMMDRALQGSPDEFDIFIRDIYGDRASNFNMDPHLLAASFGRVTRGETVRRAENFDEQSKNNAILSLLRMILYNVSQLAYMLSEISNVKRVFFNGFLVRNRPIVMKTLSFACNYWSSGKLRAYFLRHENYTTGLGAFL 347
[Close]
BLAST of SMED30027296 vs. Ensembl Celegans
Match: pnk-1 (PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:H2KYP7])

HSP 1 Score: 55.0694 bits (131), Expect = 5.314e-8
Identity = 63/215 (29.30%), Postives = 97/215 (45.12%), Query Frame = 2 
Query:  440 IHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLL-PCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAE-------TKKSITEFNKDDLAHSLVSMFIYN 1060
            IH TG G  KYSE I + L   +   DE  S   G  ++L+              D +  +    I   K Q+  I           DL+ P +   IG+G     + S  ++  V G    G TF+GL   +    +++E++EMA+RGD RNVD  V DI G  ++++L  +  +I  G +A+       TKK   +   +D+A SL+ M   N
Sbjct:  187 IHCTGGGSYKYSEIIMKELGVRLQRTDEMRSLIFGVNFLLST-----------NVDESFTYHHDAIGRNKFQYRPIAA---------DLIYPFLLVNIGTGISILKVDSPTSYERVGGSSMGGGTFMGLGSLLTPAQNFDELLEMANRGDHRNVDKLVCDIYGG-AYDELGLKADLI-AGSMAKCNRFEETTKKQ--QHKPEDIAKSLLLMVSNN 377
[Close]
BLAST of SMED30027296 vs. Ensembl Fly
Match: fbl (gene:FBgn0011205 transcript:FBtr0307392)

HSP 1 Score: 60.4622 bits (145), Expect = 9.148e-10
Identity = 46/162 (28.40%), Postives = 84/162 (51.85%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIM-GDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVC 1249
            ++ +SG    G TF+GL   + G   + E +++A++GD R VD  VKDI  GD +   L  +L     G++    K ++  +++DLA++ + + I N I +   +C ++EK+  V F GN  + + +  K  +   + +S   +   F+   H G  GA+ C
Sbjct:  133 YKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVS-VSREDLANATL-VTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLE--HEGYFGALGC 290
[Close]
BLAST of SMED30027296 vs. Ensembl Fly
Match: fbl (gene:FBgn0011205 transcript:FBtr0078188)

HSP 1 Score: 60.8474 bits (146), Expect = 9.358e-10
Identity = 46/162 (28.40%), Postives = 84/162 (51.85%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIM-GDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVC 1249
            ++ +SG    G TF+GL   + G   + E +++A++GD R VD  VKDI  GD +   L  +L     G++    K ++  +++DLA++ + + I N I +   +C ++EK+  V F GN  + + +  K  +   + +S   +   F+   H G  GA+ C
Sbjct:  210 YKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVS-VSREDLANATL-VTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLE--HEGYFGALGC 367
[Close]
BLAST of SMED30027296 vs. Ensembl Fly
Match: fbl (gene:FBgn0011205 transcript:FBtr0078190)

HSP 1 Score: 60.8474 bits (146), Expect = 9.529e-10
Identity = 46/162 (28.40%), Postives = 84/162 (51.85%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIM-GDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVC 1249
            ++ +SG    G TF+GL   + G   + E +++A++GD R VD  VKDI  GD +   L  +L     G++    K ++  +++DLA++ + + I N I +   +C ++EK+  V F GN  + + +  K  +   + +S   +   F+   H G  GA+ C
Sbjct:  192 YKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVS-VSREDLANATL-VTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLE--HEGYFGALGC 349
[Close]
BLAST of SMED30027296 vs. Ensembl Fly
Match: fbl (gene:FBgn0011205 transcript:FBtr0078189)

HSP 1 Score: 60.8474 bits (146), Expect = 9.529e-10
Identity = 46/162 (28.40%), Postives = 84/162 (51.85%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIM-GDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVC 1249
            ++ +SG    G TF+GL   + G   + E +++A++GD R VD  VKDI  GD +   L  +L     G++    K ++  +++DLA++ + + I N I +   +C ++EK+  V F GN  + + +  K  +   + +S   +   F+   H G  GA+ C
Sbjct:  192 YKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVS-VSREDLANATL-VTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLE--HEGYFGALGC 349
[Close]
BLAST of SMED30027296 vs. Ensembl Fly
Match: fbl (gene:FBgn0011205 transcript:FBtr0307393)

HSP 1 Score: 60.8474 bits (146), Expect = 9.670e-10
Identity = 46/162 (28.40%), Postives = 84/162 (51.85%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIM-GDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVC 1249
            ++ +SG    G TF+GL   + G   + E +++A++GD R VD  VKDI  GD +   L  +L     G++    K ++  +++DLA++ + + I N I +   +C ++EK+  V F GN  + + +  K  +   + +S   +   F+   H G  GA+ C
Sbjct:  219 YKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVS-VSREDLANATL-VTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLE--HEGYFGALGC 376
[Close]
BLAST of SMED30027296 vs. Ensembl Zebrafish
Match: pank4 (pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:ZDB-GENE-040426-1592])

HSP 1 Score: 75.485 bits (184), Expect = 2.938e-14
Identity = 100/365 (27.40%), Postives = 152/365 (41.64%), Query Frame = 2 
Query:  251 GLDRGCSLTKIIYV---------------------DKKDSDKVDENSTSDVIILTVAL--FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFE-KLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKMFSVNFIN------FYFVSNGHTGALGAMV 1246
             +D G SLTK+ Y                       + D D + E S  + I   +    F N+  +  L ++KD     E K   I  TG G  K+ + I++ L   V   DE     +G  ++L N+P     YA+               D + +F+          T  D+ P +   IGSG     + S+  F  + G    G TF GL   +  T  ++E++++AS+G   NVD+ VKDI G       L+ +L     GK A T K   EF+K+D+A SL+ M I N I      C+  K+HN   V+FGG   +         T    +S+NF         +    G+ GA+GA +
Sbjct:   36 AIDIGGSLTKLAYYSTVQHKVAKVRSFDHSAKVSFQETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLVNTETK--VIKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKH-------------ADSEFRFQN---------THPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATTDK---EFSKEDMAKSLLHM-ISNDIGQL--ACLYAKLHNLTRVYFGGFFIRGHPVTMHTIT----YSINFFTKGEVQALFLRHEGYLGAIGAFL 366
[Close]
BLAST of SMED30027296 vs. Ensembl Zebrafish
Match: pank4 (pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:ZDB-GENE-040426-1592])

HSP 1 Score: 75.485 bits (184), Expect = 2.938e-14
Identity = 100/365 (27.40%), Postives = 152/365 (41.64%), Query Frame = 2 
Query:  251 GLDRGCSLTKIIYV---------------------DKKDSDKVDENSTSDVIILTVAL--FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFE-KLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKMFSVNFIN------FYFVSNGHTGALGAMV 1246
             +D G SLTK+ Y                       + D D + E S  + I   +    F N+  +  L ++KD     E K   I  TG G  K+ + I++ L   V   DE     +G  ++L N+P     YA+               D + +F+          T  D+ P +   IGSG     + S+  F  + G    G TF GL   +  T  ++E++++AS+G   NVD+ VKDI G       L+ +L     GK A T K   EF+K+D+A SL+ M I N I      C+  K+HN   V+FGG   +         T    +S+NF         +    G+ GA+GA +
Sbjct:   36 AIDIGGSLTKLAYYSTVQHKVAKVRSFDHSAKVSFQETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLVNTETK--VIKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKH-------------ADSEFRFQN---------THPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATTDK---EFSKEDMAKSLLHM-ISNDIGQL--ACLYAKLHNLTRVYFGGFFIRGHPVTMHTIT----YSINFFTKGEVQALFLRHEGYLGAIGAFL 366
[Close]
BLAST of SMED30027296 vs. Ensembl Zebrafish
Match: pank4 (pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:ZDB-GENE-040426-1592])

HSP 1 Score: 64.3142 bits (155), Expect = 5.037e-11
Identity = 80/283 (28.27%), Postives = 121/283 (42.76%), Query Frame = 2 
Query:  260 RGCSLTKIIY-----------------VDKKDSDKVDENSTSDVIILTVAL--FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFE-KLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSM 1048
            RG SLTK+ Y                   + D D + E S  + I   +    F N+  +  L ++KD     E K   I  TG G  K+ + I++ L   V   DE     +G  ++L N+P     YA+               D + +F+          T  D+ P +   IGSG     + S+  F  + G    G TF GL   +  T  ++E++++AS+G   NVD+ VKDI G       L+ +L     GK A T K   EF+K+D+A SL+ M
Sbjct:   29 RGGSLTKLAYYSTVQHKVAKVRSFDHSAKETDGDPLYEISVQEEITARLHFIKFENAYIETCLDFIKDHLVNTETK--VIKATGGGAYKFKDLIEKKLKLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYAKH-------------ADSEFRFQN---------THPDIFPYLLINIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATTDK---EFSKEDMAKSLLHM 284
[Close]
BLAST of SMED30027296 vs. Ensembl Zebrafish
Match: pank1a (pantothenate kinase 1a [Source:ZFIN;Acc:ZDB-GENE-040426-2846])

HSP 1 Score: 59.6918 bits (143), Expect = 2.406e-9
Identity = 49/166 (29.52%), Postives = 85/166 (51.20%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII-----HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            ++ V+G    G TF+GL   + G   + E +EMAS+GD  NVD  VKDI G + +++   +   +     HM     +K+     +K+DLA + + + I N I +   +C ++EK+  V F GN  + + V  K  +     +S   +   F+ + G+ GA+GA +
Sbjct:  205 YKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMASKGDSTNVDKLVKDIYGGD-YQRFGLQGSAVASSFGHM----MSKEKRDSISKEDLARATL-VTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLRALFLEHEGYFGAVGAFL 364
[Close]
BLAST of SMED30027296 vs. Ensembl Zebrafish
Match: pank1a (pantothenate kinase 1a [Source:ZFIN;Acc:ZDB-GENE-040426-2846])

HSP 1 Score: 59.6918 bits (143), Expect = 2.594e-9
Identity = 49/166 (29.52%), Postives = 85/166 (51.20%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII-----HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            ++ V+G    G TF+GL   + G   + E +EMAS+GD  NVD  VKDI G + +++   +   +     HM     +K+     +K+DLA + + + I N I +   +C ++EK+  V F GN  + + V  K  +     +S   +   F+ + G+ GA+GA +
Sbjct:  206 YKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMASKGDSTNVDKLVKDIYGGD-YQRFGLQGSAVASSFGHM----MSKEKRDSISKEDLARATL-VTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLRALFLEHEGYFGAVGAFL 365
[Close]
BLAST of SMED30027296 vs. Ensembl Xenopus
Match: cidea (cell death inducing DFFA like effector a [Source:Xenbase;Acc:XB-GENE-953574])

HSP 1 Score: 61.6178 bits (148), Expect = 9.352e-10
Identity = 65/237 (27.43%), Postives = 103/237 (43.46%), Query Frame = 2 
Query:  449 TGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYM--LANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII-----HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ 1135
            TG G  K+ E  + I D  +  +DE     +G  Y+  +      E  Y E  TDT      P+  D                   +  P +   IGSG     + S   ++ V+G    G TF+GL   + G   + E +EMA++GD  NVD  VKDI G + +E+ S +   +     HM     +K+     +K+DLA + + + I N I +   +C ++E +  V F GN  +
Sbjct:  110 TGGGAYKFEEDFRTIADLQLHKLDELDCLIQGLLYVDSVGFNGRPECYYFENPTDTEQCQKKPYCLD-------------------NPYPMLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGD-YERFSLQGSAVASSFGHM----MSKEKRDSISKEDLARATL-VTITNNIGSIARMCALNENIDRVIFVGNFLR 321
[Close]
BLAST of SMED30027296 vs. Ensembl Xenopus
Match: cidea (cell death inducing DFFA like effector a [Source:Xenbase;Acc:XB-GENE-953574])

HSP 1 Score: 61.6178 bits (148), Expect = 9.446e-10
Identity = 65/237 (27.43%), Postives = 103/237 (43.46%), Query Frame = 2 
Query:  449 TGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYM--LANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII-----HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ 1135
            TG G  K+ E  + I D  +  +DE     +G  Y+  +      E  Y E  TDT      P+  D                   +  P +   IGSG     + S   ++ V+G    G TF+GL   + G   + E +EMA++GD  NVD  VKDI G + +E+ S +   +     HM     +K+     +K+DLA + + + I N I +   +C ++E +  V F GN  +
Sbjct:  114 TGGGAYKFEEDFRTIADLQLHKLDELDCLIQGLLYVDSVGFNGRPECYYFENPTDTEQCQKKPYCLD-------------------NPYPMLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGD-YERFSLQGSAVASSFGHM----MSKEKRDSISKEDLARATL-VTITNNIGSIARMCALNENIDRVIFVGNFLR 325
[Close]
BLAST of SMED30027296 vs. Ensembl Xenopus
Match: pank3 (pantothenate kinase 3 [Source:NCBI gene;Acc:100135204])

HSP 1 Score: 60.8474 bits (146), Expect = 1.629e-9
Identity = 71/275 (25.82%), Postives = 115/275 (41.82%), Query Frame = 2 
Query:  449 TGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYM--LANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLS-PELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFR-KEFSTLKKMFSVNFINFYFVSN-GHTGALGAMVCSPN 1258
            TG G  K+ E+ + I +  +  VDE     +G  Y+  L+    +E  Y E  +       +PF  D                   D  P +   IGSG     + S  +++ V G    G TF+GL   + G   + E +EMAS GD  N D  V+DI G + +E+   P   +         K      +K+DLA + +     N  + A    ++EK++ V F GN  +      K  +     +S   +   F+ + G+ GA+GA++  PN
Sbjct:  114 TGGGAYKFEEEFRMIGNLQLHKVDELDCLVKGLLYIDSLSFNGQAECYYFENASHPERCQKMPFNLD-------------------DPYPLLVVNIGSGVSILAVNSKDSYKRVCGTSLGGGTFLGLCSLLTGCESFEEALEMASAGDSTNADKLVRDIYGGD-YERFGLPGWAVASSFGNMIYKDKRESVSKEDLARATLVTITNNIGSIARMSAVNEKINKVIFVGNFLRVNTLSMKLLAYALDYWSNGQLKALFLEHEGYFGAVGALLGMPN 368
[Close]
BLAST of SMED30027296 vs. Ensembl Xenopus
Match: cidea (cell death inducing DFFA like effector a [Source:Xenbase;Acc:XB-GENE-953574])

HSP 1 Score: 59.3066 bits (142), Expect = 7.957e-9
Identity = 65/237 (27.43%), Postives = 103/237 (43.46%), Query Frame = 2 
Query:  449 TGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYM--LANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII-----HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ 1135
            TG G  K+ E  + I D  +  +DE     +G  Y+  +      E  Y E  TDT      P+  D                   +  P +   IGSG     + S   ++ V+G    G TF+GL   + G   + E +EMA++GD  NVD  VKDI G + +E+ S +   +     HM     +K+     +K+DLA + + + I N I +   +C ++E +  V F GN  +
Sbjct:  337 TGGGAYKFEEDFRTIADLQLHKLDELDCLIQGLLYVDSVGFNGRPECYYFENPTDTEQCQKKPYCLD-------------------NPYPMLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGD-YERFSLQGSAVASSFGHM----MSKEKRDSISKEDLARATL-VTITNNIGSIARMCALNENIDRVIFVGNFLR 548
[Close]
BLAST of SMED30027296 vs. Ensembl Xenopus
Match: ca1 (carbonic anhydrase I [Source:Xenbase;Acc:XB-GENE-957160])

HSP 1 Score: 57.7658 bits (138), Expect = 2.970e-8
Identity = 95/364 (26.10%), Postives = 152/364 (41.76%), Query Frame = 2 
Query:  251 GLDRGCSLTKIIYVDK---------------KDSD--KVDENSTSDVIILTVAL--FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDR--DVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDE-SFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
             +D G SLTK+ Y                  KD+D  ++ E S  + I   +    F N+  +  L ++KD     E K   I  TG G  K+ + I++ L    D    DE     +G  ++L N+P     Y +               D + +F+          T  ++ P +   IGSG     + ++  F  + G    G TF GL   +  T  ++E++++A++G   NVD+ VKDI G       L+  L     GK A   K   +F+K+D+A SL+ M I N I      C+  K HN   V+FGG        R    T+  + +S+NF +       +    G+ G +GA +
Sbjct:   40 AIDIGGSLTKLAYYSTVQHKVAKVRSFDHTGKDADHEQLYEISVQEEITARLHFIKFENAYIEICLDFIKDHLVNTETK--VIKATGGGAYKFKDLIEKKLGLKVDKEDEDEMTCLIKGCNFVLKNIPHEAFVYVKH-------------ADPEFRFQT---------THPNIFPYLLVNIGSGVSIVKVEAEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLAAKGHHTNVDMLVKDIYGGAYQILGLTGNLIASSFGKSATIDK---DFSKEDMAKSLLHM-ISNDIGQL--ACLYAKQHNLSQVYFGGFF-----IRGHPVTMHTISYSINFFSKGEVQALFLRHEGYLGTIGAFL 368
[Close]
BLAST of SMED30027296 vs. Ensembl Mouse
Match: Pank4 (pantothenate kinase 4 [Source:MGI Symbol;Acc:MGI:2387466])

HSP 1 Score: 63.929 bits (154), Expect = 2.539e-10
Identity = 82/306 (26.80%), Postives = 133/306 (43.46%), Query Frame = 2 
Query:  362 FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            F N+  +  L +++D     E K   I  TG G  K+ + I+E L   V   D      +G  ++L N+P     Y +              +D + +F+             ++ P +   IGSG     + ++  F  + G    G TF GL   +  T  ++E++++ASRG   NVD+ V+DI G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  K+H    V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:   96 FENTYMEACLDFIRDHLVNTETKV--IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKD-------------SDPEFRFQT---------NHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADR---EFSKEDMAKSLLHM-ISNDIGQL--ACLYAKLHGLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 366
[Close]
BLAST of SMED30027296 vs. Ensembl Mouse
Match: Pank4 (pantothenate kinase 4 [Source:MGI Symbol;Acc:MGI:2387466])

HSP 1 Score: 63.5438 bits (153), Expect = 2.775e-10
Identity = 82/306 (26.80%), Postives = 133/306 (43.46%), Query Frame = 2 
Query:  362 FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            F N+  +  L +++D     E K   I  TG G  K+ + I+E L   V   D      +G  ++L N+P     Y +              +D + +F+             ++ P +   IGSG     + ++  F  + G    G TF GL   +  T  ++E++++ASRG   NVD+ V+DI G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  K+H    V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:   96 FENTYMEACLDFIRDHLVNTETKV--IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKD-------------SDPEFRFQT---------NHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADR---EFSKEDMAKSLLHM-ISNDIGQL--ACLYAKLHGLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 366
[Close]
BLAST of SMED30027296 vs. Ensembl Mouse
Match: Pank3 (pantothenate kinase 3 [Source:MGI Symbol;Acc:MGI:2387464])

HSP 1 Score: 62.003 bits (149), Expect = 4.651e-10
Identity = 49/167 (29.34%), Postives = 85/167 (50.90%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLS-PELPII-HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQSEVFR-KEFSTLKKMFSVNFINFYFVSN-GHTGALGAMVCSPN 1258
            ++ V+G    G TF+GL   + G   + E +EMAS+GD    D  V+DI G + +E+   P   +    G +   +K  T  +K+DLA + + + I N I +   +C ++EK++ V F GN  +      K  +     +S   +   F+ + G+ GA+GA++  PN
Sbjct:  205 YKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASKGDSTQADRLVRDIYGGD-YERFGLPGWAVASSFGNMIYKEKRET-VSKEDLARATL-VTITNNIGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAVGALLGLPN 368
[Close]
BLAST of SMED30027296 vs. Ensembl Mouse
Match: Pank4 (pantothenate kinase 4 [Source:MGI Symbol;Acc:MGI:2387466])

HSP 1 Score: 62.003 bits (149), Expect = 6.920e-10
Identity = 51/157 (32.48%), Postives = 78/157 (49.68%), Query Frame = 2 
Query:  809 TFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            TF GL   +  T  ++E++++ASRG   NVD+ V+DI G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  K+H    V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:   79 TFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADR---EFSKEDMAKSLLHM-ISNDIGQL--ACLYAKLHGLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 224
[Close]
BLAST of SMED30027296 vs. Ensembl Mouse
Match: Pank1 (pantothenate kinase 1 [Source:MGI Symbol;Acc:MGI:1922985])

HSP 1 Score: 57.7658 bits (138), Expect = 5.795e-9
Identity = 48/165 (29.09%), Postives = 87/165 (52.73%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII--HMGKL--AETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            ++ V+G    G TF+GL   + G   + E ++MA++GD  NVD  VKDI G + +E+   +   +    G +   E ++SI+   K+DLA + + + I N I +   +C ++E +  V F GN  + + V  K  +     +S   +   F+ + G+ GA+GA++
Sbjct:   83 YKRVTGTSLGGGTFLGLCCLLTGCETFEEALDMAAKGDSTNVDKLVKDIYGGD-YERFGLQGSAVASSFGNMMSKEKRESIS---KEDLARATL-VTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHEGYFGAVGALL 242
[Close]
BLAST of SMED30027296 vs. UniProt/SwissProt
Match: sp|Q69TF4|PANK1_ORYSJ (Pantothenate kinase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=Os06g0207000 PE=2 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 3.751e-18
Identity = 89/365 (24.38%), Postives = 159/365 (43.56%), Query Frame = 2 
Query:  245 LAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPEN--------KELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVE-TTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEK--LSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMVCSPNDMEKYFQMQ 1285
            L  LD G +L K++Y         +         L  A F   +  +   +++ +     N        + + +  +G G  KY+E  +E L   +  VDE  S   GA ++L +VP +  T+                         + GK+  V+ +  +L P +   IGSG     +  +  F  V+G    G T  GL++ + G   Y+E ++++ +GD   +DL VKDI G+   +K  LS        GK+  +KK +T++  +DLA +L+S F YN    +  V     +  VFFGG+       R   ST++ + ++++F +       +    G+ GALGA++   +  +K   ++
Sbjct:   42 LLALDIGGTLIKLVYTASCGGGGAE---------LRFAKFERRRMQECFDFVRAQGLVHRNGSTMGSSKENIALKASGGGAYKYTEDFREKLGVCLDKVDEMDSVVSGANFLLQSVPGAAFTH-------------------------MNGKKSSVDISPNNLFPYLLVNIGSGVSILKVTGNRKFERVTGTHIGGGTMFGLAKLLTGCKSYDEFLQLSQKGDNFVLDLIVKDICGELVCQKQGLSTSTLASSFGKVITSKKKLTDYRPEDLASTLLSAFTYNIAQISFLVASILHLRRVFFGGS-----YIRGHKSTMQNISYAIDFWSQSKMQAVFLQHEGYLGALGALMSYGDSGDKNMNLE 367

HSP 2 Score: 65.4698 bits (158), Expect = 5.156e-10
Identity = 47/160 (29.38%), Postives = 78/160 (48.75%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEK--LSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFF-GGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSN-GHTGALGA 1240
            F  + G    G T +GL+R + G + Y+E +E++ RG+   VDL V DI G+  + K  L         GK++ ++  ++E+  +DLA +L++ F YN    A  V     +  +FF G  +   E    + S   K +S   +   F+ + G  G LGA
Sbjct:  418 FERIIGSHLGGGTILGLARLLTGCSSYDEFLELSQRGNNLAVDLTVGDIYGEHGYPKIGLPASTTAASFGKVSSSR--LSEYKVEDLAAALLNSFTYNIGQIAYFVANLSGLKRIFFRGAYICGHEKTMDKISHSLKYWSKGQVQTTFLCHEGFLGTLGA 575
[Close]
BLAST of SMED30027296 vs. UniProt/SwissProt
Match: sp|Q0J035|PANK2_ORYSJ (Pantothenate kinase 2 OS=Oryza sativa subsp. japonica OX=39947 GN=Os09g0533100 PE=2 SV=2)

HSP 1 Score: 72.0182 bits (175), Expect = 5.228e-12
Identity = 70/285 (24.56%), Postives = 122/285 (42.81%), Query Frame = 2 
Query:  419 PENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTE-DLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII--HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFIN------FYFVSNGHTGALGAMV 1246
            P+N  + I  TG G  KY++  KE L   +   DE      GA ++L ++     T+ +                         G+++ V+  + DL P +   +GSG     +   G F+ VSG    G T+ GL R +     ++E++E++ RGD   +D+ V DI G   + K+      I    GK     K ++++  +D++ SL+ M  YN    +    +   +  +FFGG   +   +  +  +    F+VNF +       +    G  GALGA +
Sbjct:  175 PDN--IVIKATGGGAFKYADLFKERLGVSLEKEDEMDCLVAGANFLLKSIRHEAFTHMD-------------------------GQKEYVQIDQNDLFPFLLVNVGSGVSIIKVDGHGKFQRVSGTNVGGGTYWGLGRLMTKCKSFDELLELSQRGDNSTIDMLVGDIYGGLDYSKIGLSASTIASSFGKTISDDKELSDYRPEDISLSLLRMISYNIGQISYLNALRYGLKRIFFGGFFIRGHAYTMDTIS----FAVNFWSKGEAKAMFLRHEGFLGALGAFM 428
[Close]
BLAST of SMED30027296 vs. UniProt/SwissProt
Match: sp|Q9NVE7|PANK4_HUMAN (4'-phosphopantetheine phosphatase OS=Homo sapiens OX=9606 GN=PANK4 PE=1 SV=1)

HSP 1 Score: 70.8626 bits (172), Expect = 1.074e-11
Identity = 82/306 (26.80%), Postives = 132/306 (43.14%), Query Frame = 2 
Query:  362 FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            F N+  +  L ++KD     E K   I  TG G  K+ + I+E L   V   D      +G  ++L N+P     Y +              +D + +F+              + P +   IGSG     + ++  F  V G    G TF GL   +  T  ++E++ +ASRG   NVD+ V+D+ G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  ++H+   V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:   96 FENTYIEACLDFIKDHLVNTETK--VIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKD-------------SDPEFRFQT---------NHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQ---EFSKEDMAKSLLHM-ISNDIGQL--ACLHARLHSLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 366
[Close]
BLAST of SMED30027296 vs. UniProt/SwissProt
Match: sp|Q4R4U1|PANK4_MACFA (4'-phosphopantetheine phosphatase OS=Macaca fascicularis OX=9541 GN=PANK4 PE=2 SV=2)

HSP 1 Score: 70.8626 bits (172), Expect = 1.093e-11
Identity = 82/306 (26.80%), Postives = 132/306 (43.14%), Query Frame = 2 
Query:  362 FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            F N+  +  L ++KD     E K   I  TG G  K+ + I+E L   V   D      +G  ++L N+P     Y +              +D + +F+              + P +   IGSG     + ++  F  V G    G TF GL   +  T  ++E++ +ASRG   NVD+ V+D+ G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  ++H+   V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:   96 FENTYIEACLDFIKDHLVNTETKV--IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKD-------------SDPEFRFQT---------NHPHIFPYLLVNIGSGVSIVKVETEDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDMLVRDVYGGAHQTLGLSGNLIASSFGKSATADQ---EFSKEDMAKSLLHM-ISNDIGQL--ACLHARLHSLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 366
[Close]
BLAST of SMED30027296 vs. UniProt/SwissProt
Match: sp|Q5R5F8|PANK4_PONAB (4'-phosphopantetheine phosphatase OS=Pongo abelii OX=9601 GN=PANK4 PE=2 SV=1)

HSP 1 Score: 68.5514 bits (166), Expect = 5.901e-11
Identity = 82/306 (26.80%), Postives = 129/306 (42.16%), Query Frame = 2 
Query:  362 FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGD-ESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKM-FSVNFIN------FYFVSNGHTGALGAMV 1246
            F N+  +  L ++KD     E K   I  TG G  K+ + I+E L   V   D      +G  ++L N+P     Y +              +D + +F+              + P +   IGSG     + +   F  V G    G TF GL   +  T  ++E++ +ASRG   NVD  V+D+ G       LS  L     GK A   +   EF+K+D+A SL+ M I N I      C+  + H+   V+FGG        R    T++ + +S+NF +       +    G+ GA+GA +
Sbjct:   96 FENTYIEACLDFIKDHLVNTETKV--IQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFVYQKD-------------SDPEFRFQT---------NHPHIFPYLLVNIGSGVSIVKVETGDRFEWVGGSSIGGGTFWGLGALLTKTKKFDELLHLASRGQHSNVDTLVRDVYGGAHQTLGLSGNLIASSFGKSATADQ---EFSKEDMAKSLLHM-ISNDIGQL--ACLHARPHSLDRVYFGGFF-----IRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFL 366
[Close]
BLAST of SMED30027296 vs. TrEMBL
Match: A0A1I8H9N6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 221.09 bits (562), Expect = 3.513e-64
Identity = 130/376 (34.57%), Postives = 215/376 (57.18%), Query Frame = 2 
Query:  170 MTENIIPIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETD---TTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMG---DESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKYFQ 1279
            M +N + I E+  + +KS + ++ V+AG+DRGCSLTK+++V   +SD        D   L +ALF N+ F+  L +L  KA     +   +H+TG G  +Y E I+E L  ++ F+DEF+SQ+RGA++++ N+P+ E+ Y E E D    T   + P   ++  QF+      +DV +    LPC+F FIGS GG  ++  +G   +V+ L  AGK+F+G  + +LGT+ Y+EIM +A RG R N+D + +D++    D  + ++   LPI   GK  + +    + +K+DLA S+V+ F+ N IN            ++F GGN F+    R+E    +  F +  +N +++  GHTGA+GAM+  P D ++Y +
Sbjct:    1 MADNFL-IEEKIVTLQKSAMENVTVMAGIDRGCSLTKVLFVTAGNSD--------DTFKLHLALFNNTHFEAGLDYLASKAILQRGEGGKLHVTGVGCDRYRELIQEKLGLELEFIDEFLSQTRGAHWLIKNLPIEELCYPETEADLGQITGRAENPLQANMNQQFQL---SSEDVASATPSLPCLFCFIGSAGGVIFLKENGESYLVTSLWMAGKSFLGFGKMLLGTSSYDEIMRLAERGRRGNIDNEGRDLVQTGVDGPYGRMPASLPIFPFGKAVDLELERNKCSKEDLAASMVAAFVTNLINLLSTSAKMTDTRSIFLGGNFFRDPFMRQEMLRQQHFFQMQSLNVHYLITGHTGAVGAMISEPTDAQRYLK 364
[Close]
BLAST of SMED30027296 vs. TrEMBL
Match: A0A267FQB3 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027093g1 PE=4 SV=1)

HSP 1 Score: 220.705 bits (561), Expect = 6.696e-64
Identity = 130/376 (34.57%), Postives = 215/376 (57.18%), Query Frame = 2 
Query:  170 MTENIIPIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETD---TTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMG---DESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKYFQ 1279
            M +N + I E+  + +KS + ++ V+AG+DRGCSLTK+++V   +SD        D   L +ALF N+ F+  L +L  KA     +   +H+TG G  +Y E I+E L  ++ F+DEF+SQ+RGA++++ N+P+ E+ Y E E D    T   + P   ++  QF+      +DV +    LPC+F FIGS GG  ++  +G   +V+ L  AGK+F+G  + +LGT+ Y+EIM +A RG R N+D + +D++    D  + ++   LPI   GK  + +    + +K+DLA S+V+ F+ N IN            ++F GGN F+    R+E    +  F +  +N +++  GHTGA+GAM+  P D ++Y +
Sbjct:   19 MADNFL-IEEKIVTLQKSAMENVTVMAGIDRGCSLTKVLFVTAGNSD--------DTFKLHLALFNNTHFEAGLDYLASKAILQRGEGGKLHVTGVGCDRYRELIQEKLGLELEFIDEFLSQTRGAHWLIKNLPIEELCYPETEADLGQITGRAENPLQANMNQQFQL---SSEDVASATPSLPCLFCFIGSAGGVIFLKENGESYLVTSLWMAGKSFLGFGKMLLGTSSYDEIMRLAERGRRGNIDNEGRDLVQTGVDGPYGRMPASLPIFPFGKAVDLELERNKCSKEDLAASMVAAFVTNLINLLSTSAKMTDTRSIFLGGNFFRDPFMRQEMLRQQHFFQMQSLNVHYLITGHTGAVGAMISEPTDAQRYLK 382
[Close]
BLAST of SMED30027296 vs. TrEMBL
Match: A0A1I8HZ40 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig034563g2 PE=4 SV=1)

HSP 1 Score: 216.083 bits (549), Expect = 3.414e-62
Identity = 131/370 (35.41%), Postives = 208/370 (56.22%), Query Frame = 2 
Query:  197 ERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDW-------FDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDES---FEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKYF 1276
            E+  + KKS    + V+ GLDRGC+LTK+++   KD +  +         L  ALF NS F+  L +LK+K    +     +H+TGAG   + E IK+ L  ++ F++EF++Q RG ++++     SE+ Y E E D +++       F    I   K    E +  +K         PC+  F+GSGGG   I  +G   MV GL  AG++F+GLS+ +LGT+DY+EI+E+AS+G R NVD +VKD++ ++    + +L P LP+   GK  +T K++ + +++DLA+S+V  F YNA         + K+  ++ GGN F+ E+ R E   + ++F+   I   F+  GHTGA+GAM+  P D  KY 
Sbjct:    9 EKIIAVKKSHFEGVGVVGGLDRGCTLTKVLFSTVKDDEHYN---------LHFALFKNSHFEAGLDYLKEKGMVVQVPGAKLHVTGAGCDMHRELIKQKLGLEIQFINEFLTQGRGTHWLIGCADDSEICYPEPELDMSEFEGLQANNFLQKLIEKAKKDLGEPIEGQK--------FPCMMLFMGSGGGIMKIEENGMSDMVGGLWFAGRSFLGLSKLLLGTDDYDEILELASKGRRNNVDTEVKDVLANDPNSPYGQLPPNLPVFPFGKAVDTDKTLADLSREDLANSIVFSFAYNAFTNLALAAQTSKIPKLYMGGNFFRHELIRAEILKIVRLFTGESIALKFLITGHTGAIGAMISKPEDEFKYL 361
[Close]
BLAST of SMED30027296 vs. TrEMBL
Match: A0A267H6I1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig034563g1 PE=4 SV=1)

HSP 1 Score: 214.542 bits (545), Expect = 1.465e-61
Identity = 131/370 (35.41%), Postives = 207/370 (55.95%), Query Frame = 2 
Query:  197 ERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDW-------FDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDES---FEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKYF 1276
            E+  + KKS    + V+ GLDRGC+LTK+++   KD +  +         L  ALF NS F+  L +LK+K    +     +H+TGAG   + E IK+ L  ++ F++EF++Q RG ++++     SE+ Y E E D +++       F    I   K    E +  +K         PC+  F+GSGGG   I  +G   MV GL  AG++F+GLS+ +LGT+DY+EI+E+AS+G R NVD +VKD++ ++    + +L P LP+   GK  +T K++ + +++DLA+S+V  F YNA         + K+  ++ GGN F+ E+ R E     ++F+   I   F+  GHTGA+GAM+  P D  KY 
Sbjct:    9 EKIIAVKKSHFEGVGVVGGLDRGCTLTKVLFSTVKDDEHYN---------LHFALFKNSHFEAGLDYLKEKGMVVQVPGAKLHVTGAGCDMHRELIKQKLGLEIQFINEFLTQGRGTHWLIGCADDSEICYPEPELDMSEFEGLQANNFLQKLIEKAKKDLGEPIEGQK--------FPCMMLFMGSGGGIMKIEENGMSDMVGGLWFAGRSFLGLSKLLLGTDDYDEILELASKGRRNNVDTEVKDVLANDPNSPYGQLPPNLPVFPFGKAVDTDKTLADLSREDLANSIVFSFAYNAFTNLALAAQTSKIPKLYMGGNFFRHELIRAEILKSVRLFTGESIALNFLITGHTGAIGAMISKPEDEFKYL 361
[Close]
BLAST of SMED30027296 vs. TrEMBL
Match: A0A1I8HLA0 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 214.542 bits (545), Expect = 4.897e-58
Identity = 131/369 (35.50%), Postives = 208/369 (56.37%), Query Frame = 2 
Query:  197 ERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDW-------FDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDES---FEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKY 1273
            E+  + KKS    + V+ GLDRGC+LTK+++   KD +  +         L  ALF NS F+  L +LK+K    +     +H+TGAG   + E IK+ L  ++ F++EF++Q RG ++++     SE+ Y E E D +++       F    I   K    E +  +K         PC+  F+GSGGG   I  +G   MV GL  AG++F+GLS+ +LGT+DY+EI+E+AS+G R NVD +VKD++ ++    + +L P LP+   GK  +T K++ + +++DLA+S+V  F YNA         + K+  ++ GGN F+ E+ R E   + ++F+   I   F+  GHTGA+GAM+  P D  KY
Sbjct:    9 EKIIAVKKSHFEGVGVVGGLDRGCTLTKVLFSTVKDDEHYN---------LHFALFKNSHFEAGLDYLKEKGMVVQVPGAKLHVTGAGCDMHRELIKQKLGLEIQFINEFLTQGRGTHWLIGCADDSEICYPEPELDMSEFEGLQANNFLQKLIEKAKKDLGEPIEGQK--------FPCMMLFMGSGGGIMKIEENGMSDMVGGLWFAGRSFLGLSKLLLGTDDYDEILELASKGRRNNVDTEVKDVLANDPNSPYGQLPPNLPVFPFGKAVDTDKTLADLSREDLANSIVFSFAYNAFTNLALAAQTSKIPKLYMGGNFFRHELIRAEILKIVRLFTGESIALKFLITGHTGAIGAMISKPEDEFKY 360
[Close]
BLAST of SMED30027296 vs. Ensembl Cavefish
Match: pank4 (pantothenate kinase 4 (inactive) [Source:NCBI gene;Acc:103021954])

HSP 1 Score: 72.0182 bits (175), Expect = 5.531e-13
Identity = 97/365 (26.58%), Postives = 152/365 (41.64%), Query Frame = 2 
Query:  251 GLDRGCSLTKIIY---------------------VDKKDSDKVDENSTSDVIILTVAL--FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFE-KLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKMFSVNFIN------FYFVSNGHTGALGAMV 1246
             +D G SLTK+ Y                     V + D + + E S  + I   +    F N+  +  L ++KD     E K   I  TG G  K+ + I++ L   V   DE     +G  ++L N+P     YA+               D + +F+          T  D+ P +   IGSG     + S+  F  + G    G TF GL   +  T  ++E++++AS+G   NVD+ VKDI G       L+ +L     GK A   K   EF+++D+A SL+ M I N I      C+  ++HN   V+FGG   +         T    +S+NF         +    G+ GA+GA +
Sbjct:   36 AIDIGGSLTKLAYYSTVQHKVAKVRSFDHTAKAGVQEADGEPLYEISVQEEITARLHFIKFENTYIETCLDFIKDHLVNTETK--VIKATGGGAYKFKDLIEKKLKLKVDKEDEMSCLIKGCNFVLKNIPHEAFVYAKH-------------ADSEFRFQN---------TRPDIFPYLLVNIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGAYGSLGLTGDLIASSFGKSATADK---EFSQEDMAKSLLHM-ISNDIGQL--ACLYARLHNLNRVYFGGFFIRGHPVTMHTIT----YSINFFTKGEVQALFLRHEGYLGAIGAFL 366
[Close]
BLAST of SMED30027296 vs. Ensembl Cavefish
Match: pank2 (pantothenate kinase 2 [Source:NCBI gene;Acc:103044193])

HSP 1 Score: 59.3066 bits (142), Expect = 3.369e-9
Identity = 93/398 (23.37%), Postives = 160/398 (40.20%), Query Frame = 2 
Query:  179 NIIPIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNS--------------KFDDALIWLKDKAF----FPENKELPIHL-----------------TGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYM---LANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLS-PELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQSEVFR-KEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            N  P  +R  S KKS         G+D G +L K++Y + KD    +E       + ++  +L S              +  D ++W +  +     FP  +ELP  L                 TG G  K+    + + D  ++ +DE     +G  Y+   +A  P  E  Y E  T   +                    ++     E+  P +   IGSG     + S   ++ V+G    G TF+GL   + G + + E +EMASRG+   VD  V+DI G + +E+   P   +         K+     +K+DLA + + + I N I +   +C ++E +  V F GN  +      K  +     +S   +   F+ + G+ GA+GA++
Sbjct:   61 NSTPARQRLDSLKKSRPPFPWF--GMDIGGTLVKLVYFEPKDI-TAEEEQEEVESLKSIRHYLTSHTAYGKTGIRDVHLELPDLILWGRKGSLHFIRFP-TQELPAFLQMGRDKHFSSLHTTLCATGGGAYKFEADFRTMADLQLLKLDELDCLIKGVLYIDSVVARGP-PECYYYENPTHPENC-------------------QQKAYNLENPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALEMASRGESTRVDKLVRDIYGGD-YERFGLPGWAVASSFGNMMCKEKRDSVSKEDLARATL-VTITNNIGSITRMCALNENIERVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLRHEGYFGAVGALL 432
[Close]
BLAST of SMED30027296 vs. Ensembl Cavefish
Match: pank1b (pantothenate kinase 1 [Source:NCBI gene;Acc:103047703])

HSP 1 Score: 58.5362 bits (140), Expect = 7.735e-9
Identity = 51/166 (30.72%), Postives = 86/166 (51.81%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII-----HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            ++ V+G    G TF+GL   + G   + E +EMA++GD  NVD  VKDI G + +E+   +   +     HM    E + SI+   K+DLA + + + I N I +   +C ++EK+  V F GN  + + V  K  +     +S   +   F+ + G+ GA+GA +
Sbjct:  283 YKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMAAKGDSTNVDKLVKDIYGGD-YERFGLQGSAVASSFGHM-MSKERRDSIS---KEDLARATL-VTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLKALFLEHEGYFGAVGAFL 442
[Close]
BLAST of SMED30027296 vs. Ensembl Cavefish
Match: pank1a (pantothenate kinase 1a [Source:ZFIN;Acc:ZDB-GENE-040426-2846])

HSP 1 Score: 53.5286 bits (127), Expect = 2.110e-7
Identity = 48/165 (29.09%), Postives = 83/165 (50.30%), Query Frame = 2 
Query:  800 AGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII-----HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSN-GHTGALGA---MVCSPND 1261
             G TF+GL   + G   + E +EMAS+GD  N D  V+DI G + +++   +   +     HM     +K+     +K+DLA + + + I N I +   +C ++EK+  V F GN  + + V  K  +     +S   +   F+ + G+ GA+GA   ++ SP D
Sbjct:  188 GGGTFLGLCCLLTGCETFEEALEMASKGDSTNADKLVRDIYGGD-YQRFGLQGSAVASSFGHM----MSKEKRDSISKEDLARATL-VTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSRGQLRALFLEHEGYFGAVGAFLELLKSPED 346
[Close]
BLAST of SMED30027296 vs. Ensembl Cavefish
Match: pank2 (pantothenate kinase 2 [Source:NCBI gene;Acc:103044193])

HSP 1 Score: 51.2174 bits (121), Expect = 1.371e-6
Identity = 82/352 (23.30%), Postives = 138/352 (39.20%), Query Frame = 2 
Query:  179 NIIPIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNS--------------KFDDALIWLKDKAF----FPENKELPIHL-----------------TGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYM---LANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLS-PELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFF 1117
            N  P  +R  S KKS         G+D G +L K++Y + KD    +E       + ++  +L S              +  D ++W +  +     FP  +ELP  L                 TG G  K+    + + D  ++ +DE     +G  Y+   +A  P  E  Y E  T   +                    ++     E+  P +   IGSG     + S   ++ V+G    G TF+GL   + G + + E +EMASRG+   VD  V+DI G + +E+   P   +         K+     +K+DLA + + + I N I +   +C   +V  + F
Sbjct:   61 NSTPARQRLDSLKKSRPPFPWF--GMDIGGTLVKLVYFEPKDI-TAEEEQEEVESLKSIRHYLTSHTAYGKTGIRDVHLELPDLILWGRKGSLHFIRFP-TQELPAFLQMGRDKHFSSLHTTLCATGGGAYKFEADFRTMADLQLLKLDELDCLIKGVLYIDSVVARGP-PECYYYENPTHPENC-------------------QQKAYNLENPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALEMASRGESTRVDKLVRDIYGGD-YERFGLPGWAVASSFGNMMCKEKRDSVSKEDLARATL-VTITNNIGSITRMCALNEVAEMGF 386
[Close]
BLAST of SMED30027296 vs. Ensembl Sea Lamprey
Match: pank2 (pantothenate kinase 2 [Source:ZFIN;Acc:ZDB-GENE-070112-1952])

HSP 1 Score: 61.6178 bits (148), Expect = 1.079e-10
Identity = 45/163 (27.61%), Postives = 88/163 (53.99%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII--HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            +R V+G    G TF+GL   + G + ++E + +A RGD  NVD  V+DI G + +E+       +    G++    +     +K+DLA + + + I N I +   +C ++EK+  V F GN  + +++ R+  +   + +S   +  +F+ + G+ GA+GA++
Sbjct:  205 YRRVTGTSLGGGTFLGLCCLLTGCDSFDEALSLAERGDSTNVDKLVRDIYGGD-YERFGLRGSAVASSFGQMISLDRR-EAVSKEDLAMATL-VTITNNIGSIARMCALNEKMERVVFVGNFLRVNQLSRRLLAHAMEYWSGGQLKAFFLEHEGYFGAVGALL 364
[Close]
BLAST of SMED30027296 vs. Ensembl Sea Lamprey
Match: pank2 (pantothenate kinase 2 [Source:ZFIN;Acc:ZDB-GENE-070112-1952])

HSP 1 Score: 55.4546 bits (132), Expect = 1.011e-8
Identity = 44/161 (27.33%), Postives = 77/161 (47.83%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQSEVFR-KEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            ++ V+G    G TF+GLS  + G   + E + +A RGD  NVD  V+DI G +      P   +         K+     +++DLA + + + I N I +   +C ++EK+  V F GN  +      K  +     +S   +   F+ + G+ GA+GA++
Sbjct:  205 YKRVTGTSLGGGTFLGLSCLLTGCKTFEEALSLAERGDSTNVDKLVRDIYGGDYGRFGLPGSTVASSFGNMMCKERREAVSREDLARATL-VTITNNIGSIARMCALNEKIDRVVFVGNFLRVNTLSMKLLAYAMDYWSKGQLKALFLEHEGYFGAVGALL 364
[Close]
BLAST of SMED30027296 vs. Ensembl Nematostella
Match: EDO37713 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEX1])

HSP 1 Score: 64.3142 bits (155), Expect = 2.710e-11
Identity = 95/374 (25.40%), Postives = 151/374 (40.37%), Query Frame = 2 
Query:  251 GLDRGCSLTKIIYVDKKDS----DKVDENSTSDVIILTVALFLNSKFDDALIWLKD--------------------KAFFPENKEL-------PIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIM-GDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQS-EVFRKEFSTLKKMFSVNFINFYFVSN-GHTGALGAMVCSPNDME 1267
            GLD G +L K++Y +   S    ++V   +  + I+  V    +   DD L  +KD                     AF    K L        +  TG G  K+    KE+L   +V  DE      G +++  N    +  Y     D    + +   T V   F+             D  P +   IGSG     + S   F  +SG    G TF+GL   + G   + E + MA+RGD   VD  VKDI  GD +   L  +      GK+   ++   E N +D+A + + M I N I +   +C ++ K+  V F GN  ++ E+  K  +     +S   +   F+ + G+ GA+GA++     ME
Sbjct:   10 GLDIGGTLLKLVYFEPYSSATCQEQVGLQALREFIMSNVQYGADGTRDDVL-EMKDVVIGGRKGNLHFIRFPTCQIGAFLEIAKSLNASVLNSKVCATGGGAFKFEHDFKEVLGVQLVKYDELECLIHGIHFI--NDHFHQECYYWTWGDQ---YSIAQATKVPYGFDS------------DPFPYLVVNIGSGVSIMAVYSAEKFDRISGTSLGGGTFLGLCCLMTGCTTFEEALSMAARGDSTKVDKLVKDIYGGDYNKFNLPGDTVASSFGKMCYPERQ-NEVNNEDIASATLIM-ITNNIGSIARMCAVNAKIERVVFVGNFLRTNEIAMKLLAYAMDYWSQGTMKALFLQHEGYFGAVGALLELMTSME 363
[Close]
BLAST of SMED30027296 vs. Ensembl Medaka
Match: pank4 (pantothenate kinase 4 (inactive) [Source:NCBI gene;Acc:101161916])

HSP 1 Score: 71.2478 bits (173), Expect = 8.118e-13
Identity = 98/361 (27.15%), Postives = 149/361 (41.27%), Query Frame = 2 
Query:  251 GLDRGCSLTKIIY-----------------VDKKDSDKVDENSTSDVIILTVAL--FLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDE-SFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHN---VFFGGNLFQSEVFRKEFSTLKKMFSVNFIN------FYFVSNGHTGALGAMV 1246
             +D G SLTK+ Y                   +  SDK+ E S  + +   +    F N+  +  L ++KD     E K   I  TG G  K+ E I++ L   V   DE     +G  ++L N+P     YA                D + +F+          T  D+ P +   IGSG     + S+  F  + G    G TF GL   +  T  ++E++++AS+G   NVD+ VKDI G       L+ +L     GK A   K   +F K+D+A SL+ M I N I      C+  K+H    V+FGG   +         T    +S+NF         +    G+ GA+GA +
Sbjct:   34 AIDIGGSLTKLAYYSTVQHKVAKVRSFDHTAKEAPSDKLYEISMQEEVTARLHFIKFENAYIETCLDFIKDHLVNTETK--VIKATGGGAHKFKELIEKKLGLKVDKEDEMTCLIKGCNFVLKNIPHEAFVYARH-------------ADSEFRFQT---------TNPDIFPYLLVNIGSGVSIVKVESEDKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLASKGQHTNVDMLVKDIYGGSYGCLGLTGDLIASSFGKSATADK---DFCKEDMAKSLLHM-ISNDIGQL--ACLYAKLHGLSRVYFGGFFIRGHPVTMHTIT----YSINFFTKGEVQALFLRHEGYLGAIGAFL 360
[Close]
BLAST of SMED30027296 vs. Ensembl Medaka
Match: pank1a (pantothenate kinase 1 [Source:NCBI gene;Acc:101175261])

HSP 1 Score: 62.7734 bits (151), Expect = 2.732e-10
Identity = 52/166 (31.33%), Postives = 88/166 (53.01%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII-----HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ-SEVFRKEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            ++ V+G    G TF+GL   + G   + E +EMAS+GD +NVD  VKDI G + +E+   +   +     HM    E + SI+   K+DLA + + + I N I +   +C ++EK+  V F GN  + + V  K  +     +S   +   F+ + G+ GA+GA++
Sbjct:  284 YKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMASKGDSKNVDKLVKDIYGGD-YERFGLQGSAVASSFGHM-MCKEKRDSIS---KEDLARATL-VTITNNIGSIARMCAVNEKIERVVFVGNFLRINTVSTKLLAYAMDFWSKGQLRALFLEHEGYFGAVGALM 443
[Close]
BLAST of SMED30027296 vs. Ensembl Medaka
Match: pank2 (pantothenate kinase 3 [Source:NCBI gene;Acc:101161204])

HSP 1 Score: 60.4622 bits (145), Expect = 1.179e-9
Identity = 67/272 (24.63%), Postives = 118/272 (43.38%), Query Frame = 2 
Query:  449 TGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYM--LANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLS-PELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQSEVFR-KEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            TG G  K+    + + D ++  +DE     RG  Y+  + +   SE  Y E  TD       P+                     E+  P +   IGSG     + S+  ++ V+G    G TF+GL   + G + + E ++MAS G+   VD  V+DI G + +E+   P   +        +K+     +K+DLA + + + I N I +   +C ++E +  V F GN  +      K  +     +S   +   F+ + G+ GA+GA++
Sbjct:  111 TGGGAYKFESDFRRMADLELHKLDELDCLVRGVLYIDSVVSWGASECYYFENPTDPEQCVQKPY-------------------NLENPYPLLLVNIGSGVSILAVYSENNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALQMASEGESTRVDKLVRDIYGGD-YERFGLPGWAVASSFGNMMSKEKRESVSKEDLARATL-VTITNNIGSITRMCALNESIERVVFVGNFLRVNTLSMKLLAYAMDYWSKGQLKALFLRHEGYFGAVGALL 361
[Close]
BLAST of SMED30027296 vs. Ensembl Medaka
Match: pank1a (pantothenate kinase 1 [Source:NCBI gene;Acc:101175261])

HSP 1 Score: 60.077 bits (144), Expect = 1.893e-9
Identity = 43/127 (33.86%), Postives = 69/127 (54.33%), Query Frame = 2 
Query:  773 FRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPII-----HMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQ 1135
            ++ V+G    G TF+GL   + G   + E +EMAS+GD +NVD  VKDI G + +E+   +   +     HM    E + SI+   K+DLA + + + I N I +   +C ++EK+  V F GN  +
Sbjct:  284 YKRVTGTSLGGGTFLGLCCLLTGCETFEEALEMASKGDSKNVDKLVKDIYGGD-YERFGLQGSAVASSFGHM-MCKEKRDSIS---KEDLARATL-VTITNNIGSIARMCAVNEKIERVVFVGNFLR 404
[Close]
BLAST of SMED30027296 vs. Ensembl Medaka
Match: pank2 (pantothenate kinase 3 [Source:NCBI gene;Acc:101161204])

HSP 1 Score: 59.6918 bits (143), Expect = 2.458e-9
Identity = 68/272 (25.00%), Postives = 118/272 (43.38%), Query Frame = 2 
Query:  449 TGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPL--SEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLS-PELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVC-MSEKVHNVFFGGNLFQSEVFR-KEFSTLKKMFSVNFINFYFVSN-GHTGALGAMV 1246
            TG G  K+    + + D ++  +DE     RG  Y+ + V    SE  Y E  TD       P+                     E+  P +   IGSG     + S+  ++ V+G    G TF+GL   + G + + E ++MAS G+   VD  V+DI G + +E+   P   +        +K+     +K+DLA + + + I N I +   +C ++E +  V F GN  +      K  +     +S   +   F+ + G+ GA+GA++
Sbjct:  171 TGGGAYKFESDFRRMADLELHKLDELDCLVRGVLYIDSVVSWGASECYYFENPTDPEQCVQKPY-------------------NLENPYPLLLVNIGSGVSILAVYSENNYKRVTGTSLGGGTFLGLCCLLTGCSTFEEALQMASEGESTRVDKLVRDIYGGD-YERFGLPGWAVASSFGNMMSKEKRESVSKEDLARATL-VTITNNIGSITRMCALNESIERVVFVGNFLRVNTLSMKLLAYAMDYWSKGQLKALFLRHEGYFGAVGALL 421
[Close]
BLAST of SMED30027296 vs. Planmine SMEST
Match: SMESG000008043.1 (SMESG000008043.1)

HSP 1 Score: 718.383 bits (1853), Expect = 0.000e+0
Identity = 371/372 (99.73%), Postives = 372/372 (100.00%), Query Frame = 2 
Query:  170 MTENIIPIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKYFQMQ 1285
            MTENIIPIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDV+TTEDLLPCIFGFIGSGGGFTYIGSDGTFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKYFQMQ
Sbjct:    1 MTENIIPIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVKTTEDLLPCIFGFIGSGGGFTYIGSDGTFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKYFQMQ 372
[Close]
BLAST of SMED30027296 vs. Planmine SMEST
Match: SMESG000008043.1 (SMESG000008043.1)

HSP 1 Score: 702.59 bits (1812), Expect = 0.000e+0
Identity = 363/364 (99.73%), Postives = 364/364 (100.00%), Query Frame = 2 
Query:  194 MERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKYFQMQ 1285
            MERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDV+TTEDLLPCIFGFIGSGGGFTYIGSDGTFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKYFQMQ
Sbjct:    1 MERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVKTTEDLLPCIFGFIGSGGGFTYIGSDGTFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMGDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKYFQMQ 364
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BLAST of SMED30027296 vs. Planmine SMEST
Match: SMESG000008042.1 (SMESG000008042.1)

HSP 1 Score: 386.341 bits (991), Expect = 2.934e-132
Identity = 194/363 (53.44%), Postives = 268/363 (73.83%), Query Frame = 2 
Query:  188 PIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIM-GDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKY 1273
            PI+ +K SFKK  L+ +EVLA LDRGCSLTK+IY DK D +  DE+ + D +ILT+ALF N+  D+ L+ LK+ A+FPEN+ LP H+TGAGG KYS++IKEIL+RDV+F+DE++SQ+RG Y+ L    L ++ Y  +E +  +  + PF +++K  F+ IV      E  ++  PCIF  +GSG G   + SDGTF M   +   GK FIG+ RCIL TN+Y EIM+MA++GDRRNVD   +DI+  D  + K+   + +I +GKLA+T K I+EFNK+D+AHSLVS+FIYNA+  AIH C++EKV  VFFGGNLFQSE+FRKE+S L+K+++++F+NFYFV+NGH+GALGAMV  P D++KY
Sbjct:    3 PIVVKKISFKKCFLNQVEVLASLDRGCSLTKVIYFDKSDKNLADEDPSIDTVILTLALFDNNNLDEVLLILKENAYFPENQTLPFHVTGAGGDKYSKRIKEILERDVIFIDEYLSQARGTYFFLKYASLEDIIYENVEIEDVEPIEAPFASNIKGHFDTIV-TNNITEEDDEKFPCIFAIMGSGAGCMRLNSDGTFHMACNMIDVGKPFIGMCRCILETNNYEEIMDMAAKGDRRNVDTTTEDIVTADSPYGKIPGGISLIPLGKLADTNKDISEFNKNDIAHSLVSLFIYNAMINAIHCCIAEKVKTVFFGGNLFQSEIFRKEYSYLRKVYTLDFVNFYFVNNGHSGALGAMVSCPEDVKKY 364
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BLAST of SMED30027296 vs. Planmine SMEST
Match: SMESG000077416.1 (SMESG000077416.1)

HSP 1 Score: 161.77 bits (408), Expect = 3.073e-45
Identity = 112/371 (30.19%), Postives = 188/371 (50.67%), Query Frame = 2 
Query:  182 IIPIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIM-GDES--FEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLV----SMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNGHTGALGAMVCSPNDMEKY 1273
            I PI     +FKK  L    +L G+D G SL+K I+V+K++  ++ + ST   I    ++F N   + AL WLK+ A+  E     IH TG G ++  ++I+   +  ++FV E ++   G    L + PL  + +     D     D   +  +  + ++ +    +   T  L P + G+ GSG    +   DG  + +      GK+F+G+++C++ +NDY+EI+  AS+G+R+N+D  +KDI+  DE   + K  PELP+   GK AE  + +  ++KDDLA SL+    S    N  NAA    ++ K   ++  GN F+S +F KE         +  + + F+  G+  ALGAM C   +   Y
Sbjct:    3 IKPIKTGLVNFKKCNLLENRILIGIDIGSSLSKFIFVNKQNRCQLYDESTHH-INFQYSIFKNEDIEKALEWLKENAYIQEGTRYEIHCTGTGCLRNKKQIESTFELGLIFVQEGLALIAGHKIALEHCPLENLIHPPTSADELYEIDNNILKTMLTRMQKRINTDTNSNKTS-LYPFVLGYWGSGSSIFFFDDDGKAQQIGSFQNGGKSFLGMAKCLIDSNDYDEIIASASKGNRKNIDTLIKDILISDEKSPYGKFPPELPVFQFGKCAENNQDLKYYSKDDLAMSLICLESSQISSNCRNAA----LTTKTKKIYLSGNTFKSSLFHKEILNRNLRHPIG-VEYTFLDLGYATALGAMFCVNQERAMY 366
[Close]
BLAST of SMED30027296 vs. Planmine SMEST
Match: SMESG000031677.1 (SMESG000031677.1)

HSP 1 Score: 149.443 bits (376), Expect = 7.311e-41
Identity = 110/367 (29.97%), Postives = 181/367 (49.32%), Query Frame = 2 
Query:  188 PIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVDENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVKYSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEV---TYAEIETDTTDWFDVPFITDVKIQFEEIVGKRKDVETTEDLLPCXXXXXXXXXXXXXXXXXXXFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDIMG---DESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAINAAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVN----FINFYFVSNGHTGALGAMVCSPN 1258
            P+     + KKS      +L  +D G SLTK+++++K     + +N     I+L   LF NS FD AL  +K+ A+FPEN    +++TG   +K  EKIK  L  + +F+DEF++ +    +++ ++ +  +    + E   +  +      + D+  +   I G         + +                         S L   GKTF+GL++CIL TNDY+EI+ +A++G++ NVD QVK++     D ++E L  E+ I   GK  +  K + +F+K DLA SL+S      I  A  +C  +KV  ++  GN+F SE+F+KE    +  F        +NF     G+ GALGAM+   N
Sbjct:    3 PLKTEFITVKKSKWIKNRLLISIDSGNSLTKLLFLNKMHY-YLLKNKEEASILLNFILFKNSDFDCALELVKNSAYFPENNNFNLYVTGVFALKNLEKIKFNLGINTIFIDEFLTIAESHRFLVEHIGVDNLLANKFMESNINKINNQSSSIMPDLYPKLFHIHGSSSGCFYFSNDIT---------------------EYWSILHQGGKTFLGLAKCILNTNDYDEIVSLATQGNKCNVDTQVKEMFDQTIDSTYE-LPSEMSIFSYGKCMDLNKGLRDFSKHDLAASLISYHAKFIIMFAASICSIKKVSKIYLTGNIFNSEIFQKEIVQFESNFPFAVKPIILNF-----GYFGALGAMLHDEN 341
The following BLAST results are available for this feature:
BLAST of SMED30027296 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PANK42.237e-1226.80pantothenate kinase 4 (inactive) [Source:HGNC Symb... [more]
PANK42.237e-1226.80pantothenate kinase 4 (inactive) [Source:HGNC Symb... [more]
PANK42.391e-1226.80pantothenate kinase 4 (inactive) [Source:HGNC Symb... [more]
PANK42.543e-1131.36pantothenate kinase 4 (inactive) [Source:HGNC Symb... [more]
PANK42.543e-1131.36pantothenate kinase 4 (inactive) [Source:HGNC Symb... [more]
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BLAST of SMED30027296 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pnk-11.085e-1127.11PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:... [more]
pnk-11.085e-1127.11PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:... [more]
pnk-11.824e-1127.11PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:... [more]
pnk-42.137e-823.27Pantothenate kinase [Source:UniProtKB/TrEMBL;Acc:... [more]
pnk-15.314e-829.30PaNtothenate Kinase [Source:UniProtKB/TrEMBL;Acc:... [more]
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BLAST of SMED30027296 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fbl9.148e-1028.40gene:FBgn0011205 transcript:FBtr0307392[more]
fbl9.358e-1028.40gene:FBgn0011205 transcript:FBtr0078188[more]
fbl9.529e-1028.40gene:FBgn0011205 transcript:FBtr0078190[more]
fbl9.529e-1028.40gene:FBgn0011205 transcript:FBtr0078189[more]
fbl9.670e-1028.40gene:FBgn0011205 transcript:FBtr0307393[more]
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BLAST of SMED30027296 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pank42.938e-1427.40pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:... [more]
pank42.938e-1427.40pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:... [more]
pank45.037e-1128.27pantothenate kinase 4 (inactive) [Source:ZFIN;Acc:... [more]
pank1a2.406e-929.52pantothenate kinase 1a [Source:ZFIN;Acc:ZDB-GENE-0... [more]
pank1a2.594e-929.52pantothenate kinase 1a [Source:ZFIN;Acc:ZDB-GENE-0... [more]
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BLAST of SMED30027296 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cidea9.352e-1027.43cell death inducing DFFA like effector a [Source:X... [more]
cidea9.446e-1027.43cell death inducing DFFA like effector a [Source:X... [more]
pank31.629e-925.82pantothenate kinase 3 [Source:NCBI gene;Acc:100135... [more]
cidea7.957e-927.43cell death inducing DFFA like effector a [Source:X... [more]
ca12.970e-826.10carbonic anhydrase I [Source:Xenbase;Acc:XB-GENE-9... [more]
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BLAST of SMED30027296 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pank42.539e-1026.80pantothenate kinase 4 [Source:MGI Symbol;Acc:MGI:2... [more]
Pank42.775e-1026.80pantothenate kinase 4 [Source:MGI Symbol;Acc:MGI:2... [more]
Pank34.651e-1029.34pantothenate kinase 3 [Source:MGI Symbol;Acc:MGI:2... [more]
Pank46.920e-1032.48pantothenate kinase 4 [Source:MGI Symbol;Acc:MGI:2... [more]
Pank15.795e-929.09pantothenate kinase 1 [Source:MGI Symbol;Acc:MGI:1... [more]
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BLAST of SMED30027296 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q69TF4|PANK1_ORYSJ3.751e-1824.38Pantothenate kinase 1 OS=Oryza sativa subsp. japon... [more]
sp|Q0J035|PANK2_ORYSJ5.228e-1224.56Pantothenate kinase 2 OS=Oryza sativa subsp. japon... [more]
sp|Q9NVE7|PANK4_HUMAN1.074e-1126.804'-phosphopantetheine phosphatase OS=Homo sapiens ... [more]
sp|Q4R4U1|PANK4_MACFA1.093e-1126.804'-phosphopantetheine phosphatase OS=Macaca fascic... [more]
sp|Q5R5F8|PANK4_PONAB5.901e-1126.804'-phosphopantetheine phosphatase OS=Pongo abelii ... [more]
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BLAST of SMED30027296 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8H9N63.513e-6434.57Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267FQB36.696e-6434.57Uncharacterized protein (Fragment) OS=Macrostomum ... [more]
A0A1I8HZ403.414e-6235.41Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267H6I11.465e-6135.41Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8HLA04.897e-5835.50Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of SMED30027296 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pank45.531e-1326.58pantothenate kinase 4 (inactive) [Source:NCBI gene... [more]
pank23.369e-923.37pantothenate kinase 2 [Source:NCBI gene;Acc:103044... [more]
pank1b7.735e-930.72pantothenate kinase 1 [Source:NCBI gene;Acc:103047... [more]
pank1a2.110e-729.09pantothenate kinase 1a [Source:ZFIN;Acc:ZDB-GENE-0... [more]
pank21.371e-623.30pantothenate kinase 2 [Source:NCBI gene;Acc:103044... [more]
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BLAST of SMED30027296 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pank21.079e-1027.61pantothenate kinase 2 [Source:ZFIN;Acc:ZDB-GENE-07... [more]
pank21.011e-827.33pantothenate kinase 2 [Source:ZFIN;Acc:ZDB-GENE-07... [more]
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BLAST of SMED30027296 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30027296 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO377132.710e-1125.40Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMED30027296 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pank48.118e-1327.15pantothenate kinase 4 (inactive) [Source:NCBI gene... [more]
pank1a2.732e-1031.33pantothenate kinase 1 [Source:NCBI gene;Acc:101175... [more]
pank21.179e-924.63pantothenate kinase 3 [Source:NCBI gene;Acc:101161... [more]
pank1a1.893e-933.86pantothenate kinase 1 [Source:NCBI gene;Acc:101175... [more]
pank22.458e-925.00pantothenate kinase 3 [Source:NCBI gene;Acc:101161... [more]
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BLAST of SMED30027296 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000008043.10.000e+099.73SMESG000008043.1[more]
SMESG000008043.10.000e+099.73SMESG000008043.1[more]
SMESG000008042.12.934e-13253.44SMESG000008042.1[more]
SMESG000077416.13.073e-4530.19SMESG000077416.1[more]
SMESG000031677.17.311e-4129.97SMESG000031677.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027296 ID=SMED30027296|Name=SMED30027296|organism=Schmidtea mediterranea sexual|type=transcript|length=1358bp
GCCAAAGATTAAAACGCAAACCCTGTGAAATTCAATCAGTGTACCAGGGT
TGAAGGTCACGACAGTCAATCAGCGTTTATAAAAATCCACTTAATTTTAT
TCTGAAAAATAACGATATAAATTGCGAAAATGTCATTTAATCACTAAGAT
TACAAAAGCCCATCAAAAAATGACTGAAAATATTATTCCTATAATGGAGA
GAAAATTCTCGTTCAAAAAATCAGTTTTGAGTCATATTGAGGTCCTAGCG
GGTTTGGATCGAGGCTGCTCGTTGACGAAAATAATTTATGTCGACAAAAA
AGACTCGGATAAAGTTGATGAAAACTCAACCAGCGATGTGATAATTCTGA
CAGTTGCTTTATTTCTGAACTCAAAATTCGACGATGCTCTCATCTGGCTA
AAGGACAAGGCATTCTTTCCAGAAAATAAAGAATTACCAATTCATTTGAC
TGGAGCCGGAGGAGTAAAATATAGTGAAAAGATAAAAGAGATACTGGATA
GAGATGTTGTATTTGTTGATGAATTTATGTCCCAGTCAAGAGGTGCATAT
TATATGTTGGCAAATGTTCCCTTGTCCGAAGTAACATATGCAGAAATAGA
AACCGACACTACCGATTGGTTTGATGTGCCATTCATAACCGATGTTAAGA
TTCAATTTGAGGAAATCGTTGGTAAACGAAAAGACGTTGAAACTACCGAG
GATTTATTGCCATGCATTTTTGGATTTATTGGAAGTGGAGGTGGGTTTAC
TTACATTGGATCCGACGGAACCTTTCGCATGGTCAGTGGTCTTCCTGCAG
CTGGAAAAACCTTTATTGGTTTGTCTAGATGCATTCTTGGAACAAATGAT
TACAATGAAATTATGGAAATGGCGTCCAGAGGAGACAGAAGAAATGTTGA
TCTTCAAGTAAAAGATATTATGGGAGATGAATCTTTTGAGAAACTTTCTC
CAGAACTTCCAATAATTCACATGGGAAAGCTGGCTGAAACAAAAAAGAGT
ATAACAGAATTTAATAAAGATGATTTAGCGCACTCGCTAGTCTCTATGTT
TATATACAATGCAATTAATGCTGCAATTCATGTTTGTATGTCGGAAAAAG
TTCATAACGTATTTTTTGGAGGAAACCTTTTCCAATCTGAAGTTTTTCGA
AAAGAATTCAGCACTCTTAAGAAAATGTTTTCAGTAAACTTTATTAATTT
CTATTTCGTCAGTAATGGTCACACTGGAGCTCTTGGGGCCATGGTTTGCT
CTCCCAATGATATGGAAAAGTATTTCCAAATGCAATAAAAAAAATAATGT
CACTTCTGTCTTGATTGATTTTAGTAAGATTAAATTAATAAAAAAATGGT
TCGTTTTG
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protein sequence of SMED30027296-orf-1

>SMED30027296-orf-1 ID=SMED30027296-orf-1|Name=SMED30027296-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=373bp
MTENIIPIMERKFSFKKSVLSHIEVLAGLDRGCSLTKIIYVDKKDSDKVD
ENSTSDVIILTVALFLNSKFDDALIWLKDKAFFPENKELPIHLTGAGGVK
YSEKIKEILDRDVVFVDEFMSQSRGAYYMLANVPLSEVTYAEIETDTTDW
FDVPFITDVKIQFEEIVGKRKDVETTEDLLPCIFGFIGSGGGFTYIGSDG
TFRMVSGLPAAGKTFIGLSRCILGTNDYNEIMEMASRGDRRNVDLQVKDI
MGDESFEKLSPELPIIHMGKLAETKKSITEFNKDDLAHSLVSMFIYNAIN
AAIHVCMSEKVHNVFFGGNLFQSEVFRKEFSTLKKMFSVNFINFYFVSNG
HTGALGAMVCSPNDMEKYFQMQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0002142parenchyma
PLANA:0003116parenchymal cell
PLANA:0007528glial cell
Vocabulary: INTERPRO
TermDefinition
IPR043129ATPase_NBD
IPR004567Type_II_PanK
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0004594pantothenate kinase activity
GO:0000166nucleotide binding
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0015937coenzyme A biosynthetic process
GO:0016310phosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.30.420.40coord: 137..351
e-value: 6.5E-40
score: 139.3
NoneNo IPR availableGENE3DG3DSA:3.30.420.510coord: 28..358
e-value: 6.5E-40
score: 139.3
NoneNo IPR availableGENE3DG3DSA:1.10.8.780coord: 240..282
e-value: 6.5E-40
score: 139.3
NoneNo IPR availablePANTHERPTHR12280PANTOTHENATE KINASEcoord: 27..359
NoneNo IPR availablePANTHERPTHR12280:SF20PANTOTHENATE KINASE 4coord: 27..359
IPR004567Type II pantothenate kinasePFAMPF03630Fumblecoord: 28..359
e-value: 9.3E-44
score: 149.9
IPR043129ATPase, nucleotide binding domainSUPERFAMILYSSF53067Actin-like ATPase domaincoord: 27..133
IPR043129ATPase, nucleotide binding domainSUPERFAMILYSSF53067Actin-like ATPase domaincoord: 109..360