Protocadherin Fat 4
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30027114 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Protocadherin Fat 4 vs. Ensembl Human
Match: NOTCH3 (notch receptor 3 [Source:HGNC Symbol;Acc:HGNC:7883]) HSP 1 Score: 108.612 bits (270), Expect = 1.171e-22 Identity = 64/169 (37.87%), Postives = 87/169 (51.48%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFC--LGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 +CH + SN CH +A C +N +N C C PGF G G+ +++DEC N C LG RC++ F C CG +G CE VN CL C + C D +C+C++G+ G C ID+C PC GVC+D +NGF C C F+G C+ D C Sbjct: 348 LCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPCEHLG---RCVNTQGSFLCQCGRGYTGPRCET-DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDEC 511 HSP 2 Score: 91.2781 bits (225), Expect = 2.044e-17 Identity = 55/179 (30.73%), Postives = 84/179 (46.93%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 + I S+ C CK + F C C GF +GS+C+ ++DEC C + ++C+D + ++C C G C+ V+ C C HG C D SC C G+ G C +D+C PC G C D ++ ++C C TG+ CE + C + FGVC + N+ Sbjct: 468 VDIDECQSSPCVNGGVCKDRV--NGFSCTCPSGF--SGSTCQLDVDECASTPCR-NGAKCVDQPDGYECRCAEGFEGTLCD-RNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINR 640 HSP 3 Score: 87.8113 bits (216), Expect = 2.227e-16 Identity = 56/177 (31.64%), Postives = 81/177 (45.76%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 ++C N + C + C D F C C PG+ G+ CE ++DEC C +C+DLV+ + C C S +G CEV ++ C + C G+CRD C+C G+ G CN I++C PC G C D NGF C C C C + + G+C + Sbjct: 540 TLCDRNVDDCSPDP-CHHGRCVDGIASFSCACAPGY--TGTRCESQVDECRSQPCR-HGGKCLDLVDKYLCRCPSGTTGVNCEV-NIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYD 711 HSP 4 Score: 87.4261 bits (215), Expect = 3.596e-16 Identity = 58/173 (33.53%), Postives = 77/173 (44.51%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS----CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLN 5682 S+ C A C + F C C PG+ G SC ++DEC C++ F+C C + +G CE V C S C +G CR C CL G+EG +C ++DDC G C G C D +N + C C +TG FC D C+ N N G C N Sbjct: 125 SSPCAHGARCSVGP-DGRFLCSCPPGY--QGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP-CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFN 293 HSP 5 Score: 83.1889 bits (204), Expect = 5.437e-15 Identity = 65/186 (34.95%), Postives = 79/186 (42.47%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE--FDHFSCKNCSENFGVCLNLKNKNQYCL 5709 C + N C N D F C C PGF G + ++DECL N C C D V F C C G CE + C S C +G C D SCLC G+ G C D C+ PC GVC A GF C C ++FTG C+ D S + C +N G C+ YCL Sbjct: 846 CDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCA-RDVDECLSNPC--GPGTCTDHVASFTCTCPPGYGGFHCE-QDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPC-QNGGRCV---QTGAYCL 1023 HSP 6 Score: 83.1889 bits (204), Expect = 6.168e-15 Identity = 54/167 (32.34%), Postives = 81/167 (48.50%), Query Frame = 1 Query: 5200 CHRNATCK-SNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLC-LKSDCVH--GICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C TC+ S +L + C C PGF G +CE +D+C + CL + C+D VN + C C + +G+ C V+ C L+ + H G C + +SC+C++GW G C+++IDDC C C D + F C C TG+ C D N +C Sbjct: 206 CRNGGTCRQSGDLT--YDCACLPGF--EGQNCEVNVDDCPGHRCL-NGGTCVDGVNTYNCQCPPEWTGQFC-TEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAIC 366 HSP 7 Score: 79.7221 bits (195), Expect = 6.831e-14 Identity = 56/175 (32.00%), Postives = 73/175 (41.71%), Query Frame = 1 Query: 5179 CHFNSNKCHRN----ATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS---CLCLSGWEGIDCNKSI--DDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C N + C N C+ + + C C PGF G + E I+EC + C G+ C+D N F+CLC C + + C C HGIC D C+C GW G C++S+ D C PC G C GF C C G CE N E+ G C Sbjct: 617 CEVNIDDCASNPCTFGVCRDGI--NRYDCVCQPGFTGPLCNVE-INECASSPC-GEGGSCVDGENGFRCLCPPGSLPPLC-LPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRC 786 HSP 8 Score: 73.1738 bits (178), Expect = 7.137e-12 Identity = 51/164 (31.10%), Postives = 72/164 (43.90%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS------CLCLSGWEGIDCNKSIDDC-IG-DPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C N CH TC N L C C G+ G S + ID+C C ++ C D V F C C ++G C + + C+ + C D N C C G+ G C++ +D+C IG +PC G C + F+C C + +TG CE D C Sbjct: 278 CQLQPNACHNGGTC-FNTLGGH-SCVCVNGWTGESCS-QNIDDCATAVCFHGAT-CHDRVASFYCACPMGKTGLLCHL--DDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNEC 435 HSP 9 Score: 70.8626 bits (172), Expect = 3.802e-11 Identity = 43/145 (29.66%), Postives = 63/145 (43.45%), Query Frame = 1 Query: 5251 CFCNPGFVGN---------GSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C C PG+ G + +I L C +C+D + C+C R+G CE +V+ CL C HG CR C CL G+ G +C +D+C PC G C D + ++C+C G+ CE + C Sbjct: 1022 CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQA-GGQCVDEDSSHYCVCPEGRTGSHCE-QEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1164 HSP 10 Score: 69.3218 bits (168), Expect = 9.586e-11 Identity = 51/169 (30.18%), Postives = 67/169 (39.64%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQ-CLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 S C TC S+ + F C C PG G CE + C N C RC C C G C+ + C HGIC + SC C G+ G C++ I+DC +PC G C+D + F C+C F G C D C + G C + Sbjct: 740 SQPCRAGGTCSSDGMG--FHCTCPPGV--QGRQCELLSPCTPNPC-EHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTD 903 HSP 11 Score: 65.4698 bits (158), Expect = 1.656e-9 Identity = 48/155 (30.97%), Postives = 62/155 (40.00%), Query Frame = 1 Query: 5242 EFQCFCNPGFVGNGSSCEEIDECLFNFCLGD---SSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI-CRDDNS----CLCLSGWEGIDCNKSIDDC-IGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVC 5676 E C C PG+V G C+ D C C G S + F C C G C + + CL S C HG C C C G++G C +D+C +G+PC G C + F C C +TG CE C + N G C Sbjct: 62 EAACLCPPGWV--GERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSL--PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC 212 HSP 12 Score: 60.077 bits (144), Expect = 6.045e-8 Identity = 52/179 (29.05%), Postives = 67/179 (37.43%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRC------IDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD-------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN-----GFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 S C +C +L + C C PG +G E D+C L RC +DLV F+C C +G CE +N C C RD CLC +G+ G C + C PC G C + F C+C Q F G CE SC+ GV Sbjct: 1128 SQPCQHGGSCI--DLVARYLCSCPPGTLGVLCEINE-DDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-DINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGV 1302 HSP 13 Score: 59.3066 bits (142), Expect = 1.214e-7 Identity = 48/146 (32.88%), Postives = 62/146 (42.47%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDP-------CNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN 5652 C C G GS CE E+D CL C + C + + C C +G CE V+ C C HG C D + C C G G+ C + DDC P C G C D + GF C C +TG+ CE D C++ Sbjct: 1070 CVCPEG--RTGSHCEQEVDPCLAQPCQHGGT-CRGYMGGYMCECLPGYNGDNCED-DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRS 1211
BLAST of Protocadherin Fat 4 vs. Ensembl Human
Match: FAT4 (FAT atypical cadherin 4 [Source:HGNC Symbol;Acc:HGNC:23109]) HSP 1 Score: 104.76 bits (260), Expect = 2.202e-21 Identity = 282/1309 (21.54%), Postives = 522/1309 (39.88%), Query Frame = 1 Query: 142 TNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWK--VEENILVGSLVGQISVVDEDLDDSFKCSVK---SDSPFNVDANFNLFT-KAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINEAPDKI---YVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--------------NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNN-------NSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNE----LWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY---FIQLIDVNE------APQGLTLYPSTVTENIPSGSVIGKFSILDSNL--NSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFY---IENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNE--PPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSI----LNCLNCNEKFEFSNGG-SKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND-PPTVAGLNFTMIPSFVEK-DFIIGKVNVFDEDNLSTYNQIECSIIK--PLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDIN-NEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVS---NNIKIQINEDNSFMLTDPLDYET----ENNFLISFTLIDKNSNQSINLK------VQILDVNE-APSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKI-VNNELLTDVNSLDVVVSNYITY-----FWVEILCRDDGQPSLSIQSRFYIQIINVNDG----PTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSY--FGIS--NSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQ--IDIEDVNEPPENVKISN--DQWNEKSEIGLLIANLSANDPEG 3768 T L + +D PK ++V + D ND P S+++ V E+ +VGS V Q++ D D + + +PF +D L T + PLD+E + ++ + ++ +D S+ + E I + D+N+ + Y T+ + +EN++ GT + ++ D D N+ F S+ V L+ I++ L + ER +SV+D + S + ++I D N + L EE + +SA D D + + I+ + + H +E + S L+ E + + A +DQ + +Y + L+DVN+ P+G Y +V EN P+G+ + D +L N T+ + T F + L + LD E+ Y+L + TD G + I + + D N+ I ENEP G I ++A D D N T+ Y++ ++ + ++ + + D E + YQ+ I D G+ + I +L++ +NP + + Y F + EN L +++ D + I+ I + + QK N LT +D E+ +++++ + + T + I V+++N+ P AI+ +N+ EN Q SI DPD+ N ++ YS+ N NEK NG S L + Y+ I++L + LS + + + + D ND P L++ + S E + KV D+D+ + +I +I + F I Q L I + R + ++++ + + ++ + S T + + +ED+N N P S N+T F E +G++ + + ++ S +V + I +I + F D E+ + SFT+I + LK V + D+N+ AP +K F + T+ E + + A+D D N + ++SI+K + D S V + + Y + + I D G L+ I I++ ND P + ++ L ++ +++V A ++ D + G+N++ F IS SI++AK+LD+ET + + + DQ SS I + D N+ P + + E IG + +++A+DP+ Sbjct: 213 TPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSR--YASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPN---------------LSLIKVASAL--DRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISA-RDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEG---YDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYS-----FVVFENVALGYHVGSVSASTMDLNSNISYLITTGD-----QKGMFAINQVTGQLTTANVIDREEQSFYQLKV-VASGGTVTGDTMVNITVKDLNDNSPHFLQAIES-----VNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEK----NGTISLLGPLDVHAGSYQ------IEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGAN-GEIAYTIAEGNTGDAFGIFPDGQ-LYIKSELDRELQDRYVLMVVA--SDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITNTHQF------DRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQ-ATISESAANLTQVLRVSASDVDEG------------NNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDA 1449 HSP 2 Score: 93.2041 bits (230), Expect = 6.443e-18 Identity = 52/150 (34.67%), Postives = 79/150 (52.67%), Query Frame = 1 Query: 5224 SNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS 5658 +NE F C C PG+ G S CE +IDECL + C + C +LV F C C +GR CE +N CL+S C +G IC++ +C+C +G+ G C S++ C +PC G C+ ++ + C+C G CE + + + S Sbjct: 3839 ANEPLQPFLCKCLPGYAG--SWCEIDIDECLPSPCHSGGT-CHNLVGGFSCSCPDGFTGRACE-RDINECLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCELNSYGFEELS 3984 HSP 3 Score: 91.2781 bits (225), Expect = 2.573e-17 Identity = 248/1111 (22.32%), Postives = 461/1111 (41.49%), Query Frame = 1 Query: 1144 KTYFIQLIDVNEAPQGLTL--YPSTVTENIPSGSVIGKFSILDSN--LNSTIEKCSLQLITFNEIFLISQFQLE----LKDNTRLDYEKTPAYNLGIRVTDYGQ---ENIVTDFEIILEISDANERPEN-LSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTV---------FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFA-TITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNE--PPTKLAIDGSREIIINITENIQGY-QSIANFITTDPDQNDVIKYS-ILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND--PPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDY---SNKSLQISKSSIIVLVSNNIKIQINE-DNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDV-VVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAIN---YLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSN--SYFGISNSS--IYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNE---PPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSS-IFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDV---MNLPENSPIGSKVLEIQINFLSNFMPNINCEIF----SDGNFFII-VDFKVLLNKS-LDYET---------NSHIMVTVKCFQNKLQILKKLSTTINVTD 4254 + YF ++DVN+ P +L Y +++ EN+P GS + F++ D++ +NS + + + + + + QF ++ LK LD E YNL ++V D Q + ++ + + D N+ P LS IPEN PI ++ A D D NS + YTL NK GT+ D E Y +T+ D G P L+ S + +L+ N+N I + Y K E+ NE +T I VF D D+ N Q+ ++ I ++ +T+ + LD E+ + + ++ D + T + I + ++N+ P +L+ +N+ EN+ ++I + D D+ K S +L N + F S G L +Q D E+ + ++I A DSG L+ + + + D ND P + FT IP + VN D D ++ N + II F+I N S +I+T+A +D + D + + C + G + S++ S + + D+N+ P F + V + + S + +TD N L S S N+ K I+ + M PL+ +E F S + D S S + V+ ++ + P ++++ E+ E P + + T + + + I +G + N + + ++ LD + Y+ W+E RD G P S + I +++VND +++++ I TV A+ + + ++ N + F I++++ I + LD E + + D+ + S+ ++ I ++E P +I + E S +G + ++ +D + S + PF I ++ I +++ L + D+ V+ D + ++S +VTIF ++ + F ++ PE + IGSKV ++ F ++ N ++F S +F I + NK L Y+ N H + + K ++ + + TIN+ D Sbjct: 1929 RVYF-NILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINS---QLTYSIASGDSL---GQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTL------LNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALY--KVEI------NENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGA-ITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELS-----PYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGE---LGVTQSLDRETK--ERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDAD--ASKNAV-IRIIGGNSQFTI-NPSTG-QIITSA--LLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSG-----RNSEKFHIDPLRGAIMAAGPLNGASEVTF--SVHVKDGGSFPKTDSTTVTVRFVNKADFP-KVRAKEQTFMFPENQPVSSLVTTITGS-----SLRGEPMSYYIASGNLGNTFQIDQLTGQVSIS-QPLDFEKIQKYVV--WIE--ARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTINPSTGDIVISRPLN-REDTDRYRIRVSAHD---SGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQV---FATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVD 2975 HSP 4 Score: 82.4185 bits (202), Expect = 1.291e-14 Identity = 136/551 (24.68%), Postives = 241/551 (43.74%), Query Frame = 1 Query: 736 EIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINE----LYSFQILI----LHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKD--QILIFNKTYFIQLIDVNE-APQGLT-LYPSTVTENIPSGSVIGKFSI--LDSNLNSTIEKCSLQLITFNE--IFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDV--NEKDFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFH-IMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMK-----NFTAIMKIFIFVENVNE------PPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILN 2250 ++ I+ EL + E Q + +DR LS V + ++ D N N + EE + +G++SA+D+D YSF+++ LH S EI + ++ + +ES ++ ++ V+ + Q L T + + D+N+ AP+ L Y +T++E+ + + + + S +D N I +I NE F I ++ +LDYE TPAY+L I+ D G + + + ++I D N+ + S + EN IG L++ + A D+D N+ L Y++ N F I N +G++F D E + Y++ IT D G P + + + I + + N+NP ++F I+EN + + ++T +PD D IN Q+ + + ++ N F D + N +D E N FE+ ++ ND A+ + I V ++N+ LA D S I +T + DPD+ N I+Y I+N Sbjct: 1051 QLYIKSEL--DRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITNTHQ-FDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIH---YSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPN---TGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPG------DIFKSIVENIPIGTSVISVTAHDPDAD--INGQL-----SYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVIGSVLT----------TIMAADPDEGANGEIEYEIIN 1569 HSP 5 Score: 77.411 bits (189), Expect = 3.672e-13 Identity = 144/710 (20.28%), Postives = 286/710 (40.28%), Query Frame = 1 Query: 1234 GSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ--IPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVF-HIMENNELEMTFATITVFE---PDFDDKINCQIISDN-SRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND---------MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG---GLSIDLEVPISIQDANDPPTV----AGLNFTMI---PSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKS-SIIVLVSNNIKIQINEDNSFMLTD-PLDYETENNFLISFTLIDKNSNQSIN---LKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLT 3252 G+ G+F LD LN + E L L++ LD E TP Y L + V D G+ ++ + + D N+ P S+ Q +PE+ +G + + A D D+ N+ + Y L F + E + D E R Y +T+ D G P L I++L+ N+N + ++K +Y T + + EN ++ A +TV + P + I+ QI+ N R + S++ N+ + + LD E+ + + + ++D ++ +++ + IFV ++N+ P + R +N++E ++ TD D N ++YSI++ N F S + S D E + I + I A D G +S ++ +++ D ND V G + +++ P+ E + ++ ++ E + + F + +S L +++ R ++ F + + + G + +S+ +++ DIN+ F + V + N G + ++ L + + + + + Q+N + + T LD E + + + D + QS N + + +LD + P + +FE H+ + A+ D N +I +I G+ + V +L T Sbjct: 179 GNEAGRFR-LDITLNPSGEGAFLHLVS----------------KGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDN-DPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL--IKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYR---VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSG-NGLGWFHISEHSGLVTTGSSGGLDRE--LASQIVLNISARDQGVHPKVSY-AQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDR--RSFRLDPVSGRLSTISSLDRE-EQAFYSLLVLATDLG-SPPQSSMARINVSLLDINDNSPVF---YPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNS----NISYLITTGDQKGMFAINQVTGQLTT 850 HSP 6 Score: 72.0182 bits (175), Expect = 1.485e-11 Identity = 282/1272 (22.17%), Postives = 485/1272 (38.13%), Query Frame = 1 Query: 211 IHVAILDAND-PPT-NIQLSNWKVEENILVGSLVGQISVVDEDLDD----SFKCSVKSDSPFNVDA-NFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKII--ILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYES-SYVNYFVVGAYKDQILIFNKTYFIQ----LIDVNEAPQGLTLYP--STVTENIPSGSVIGKFSIL--DSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNE---KDFYIEN--NKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMEN-NELEMTFATITVFEPDF--DDKINCQIISDN--SRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGG----LSIDLEVPISIQDAND-PPTVAGLNF-TMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKF-IDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFV----------TENSNNISLGQLL--LMTDYSNKSLQISKSSIIVLVSN-NIKIQINE-DNSFMLTDPLDYETENNFLISFTLIDKN---SNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVND-GP-------------TAINY-LTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGI--SNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQW----NEKSEIGLLIANLSANDP-EGSQVQ 3780 + + + D ND PP + + VEENI GS + Q++ +D D ++ +D F +D + +L LD E ++++ +++ D SS + + I+V+D+N+ K + E++ G+ + I D D N + + N D L I F L + + + Y+ ++V + +++ IL+V++NP LN +++ + S + ++ D+ IN ++ I + KN + +K L+ ES S+ N V QI T Q L+DVN+ P L P + + EN P +V+ K DS NS IE L F I E++ LD E+ Y L + TD GQ ++ + E+++ + D N+ +L +I EN G I + A D D+ N + Y + VN ++F I++ + D E P Y +T+ D G + T I +L+ N+ + Y ++ EN L T + + D + K++ + N + F + E L + Q+LD E F + I D + T I + V++VN+ A S+ I E+ + + + + D K +++ + N +F + ++ S D E+ KD L+ G LS V +++ D ND PP + T IPS + V V D D I N E+ + + EKF ID ++ + ++ ++D + P T S TV FV E + Q + L+T + SL+ S + N QI++ ++ PLD+E +++ D + L + +LDVN+ K + E P I T A D D D + IVNG + N + E+ + V LD ++++ + I D G PS S + I I++ ND P + + Y +T++T E IN + + ++ F I S I I++ L+ E + V D SG VS+ I + D+N+ + S + E +EIG + + A DP EGS Q Sbjct: 1726 VEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQSSDM-RINITVSDVNDHTPKF----SRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFF------------LNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGV-LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF-LSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLN--PLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGI-VNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYS-----VNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGE--------LGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFA---SKAYFTTIPEDA---PTGTDVLLVNASDADASKNAVIRIIGGNSQFTINPSTGQIIT--SALLDRET---KDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDAD-----------------------IGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR-KILTVSAMDKDSGPNGQLDYE--IVNGNMENSFSINHATGEIRS-VRPLD---REKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAI------------SRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHD-SGWTVSTDVTIFVTDIND--NAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQ 2906 HSP 7 Score: 67.781 bits (164), Expect = 3.570e-10 Identity = 36/125 (28.80%), Postives = 50/125 (40.00%), Query Frame = 1 Query: 5413 LKVNLCLKSDCVHGICRDDNSCL-------------------------------CLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKN 5691 +KV CVHG C++ SCL CL G+ G C ID+C+ PC+ G C + + GF C+C FTG CE D C ++ +N +C N Sbjct: 3796 VKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPG 3920 HSP 8 Score: 63.929 bits (154), Expect = 4.277e-9 Identity = 35/110 (31.82%), Postives = 52/110 (47.27%), Query Frame = 1 Query: 5365 FQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE--FDHFSCKNCSENFGVC 5676 F C C +G CE+ ++ CL S C G C + SC C G+ G C + I++C+ PC +C++ F C C+ +TG CE ++ C C N G C Sbjct: 3846 FLCKCLPGYAGSWCEI-DIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCF-NGGSC 3953 HSP 9 Score: 55.0694 bits (131), Expect = 2.105e-6 Identity = 97/446 (21.75%), Postives = 178/446 (39.91%), Query Frame = 1 Query: 1018 DSVEIKHKNELWIKESAELNYESSYVNYFVVG--AYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIE-KCSLQLITFNEIFLISQFQLELKDNTRLDYEK------TPAYNLGIRVTDYGQENIVTDFEII-LEISDANERPENLSLSNNQIPENEPIGLLIAI--INAQDNDK--NSTLVYTL--DVNEKDFYIENNKLLSGTV-----FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINC--QIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKF 2274 D+ I +L+IK + + YV V A + N T ++ ++ N T Y E +GS +GK S +D + E + S +++ + F + E+ + + D E T ++ + TD G + D + + + D N+ Q +E L + ++A D D+ N + Y++ E+ F I++ SG V D+E P Y + I D+G LN + T +I+IL+ N+N + T ++EN + +++T + D D + I N+ +IF + + LD+E + +++NI D ++ M + I V + N+ P +I +I ENI S+ + DPD N + Y+I+ + F Sbjct: 1042 DAFGIFPDGQLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPD--FELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNEERQFAIDST---SGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDN-----TPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIF-----LAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFP---PGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHF 1469
BLAST of Protocadherin Fat 4 vs. Ensembl Human
Match: NOTCH1 (notch receptor 1 [Source:HGNC Symbol;Acc:HGNC:7881]) HSP 1 Score: 98.2117 bits (243), Expect = 1.685e-19 Identity = 60/183 (32.79%), Postives = 93/183 (50.82%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKN 5691 +CH N SN C+ + C +N +N + C C G+ G S +++DEC N C + +CI+ + F+C C +G CE+ VN C+ + C + C D + C+C+ G+EG+ C + D+C PC G C D +N F C C FTG C++D C + +N CL+ N Sbjct: 369 LCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACS-QDVDECSLGANPC-EHAGKCINTLGSFECQCLQGYTGPRCEI-DVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPN 548 HSP 2 Score: 95.1301 bits (235), Expect = 1.659e-18 Identity = 60/176 (34.09%), Postives = 89/176 (50.57%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDE---FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 C N + C ++ C S D+ ++C C PG+ GS C IDEC N C + C D +N F C C TC + +VN C + CVHG CRD C C GW G +C+ + ++C +PC G C+D +G++C C++ F+G C+ + C N N G C++ Sbjct: 638 CEINLDDC-ASSPCDSGTCLDKIDGYECACEPGY--TGSMCNINIDECAGNPC-HNGGTCEDGINGFTCRCPEGYHDPTC-LSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCID 808 HSP 3 Score: 91.6633 bits (226), Expect = 1.775e-17 Identity = 62/181 (34.25%), Postives = 92/181 (50.83%), Query Frame = 1 Query: 5179 CHFNSNKCHRN-----ATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN-----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVCLN 5682 C N+N+C N TCK ++ + C C GF +G +C+ I+EC N CL + CID V ++C C +G TCEV+ + C S C +G CR SC+C +GW+G C I++C+ PC C++ G+ C+CQ ++G CE D C+ N N G C + Sbjct: 750 CDINNNECESNPCVNGGTCK--DMTSGYVCTCREGF--SGPNCQTNINECASNPCLNQGT-CIDDVAGYKCNCLLPYTGATCEVV-LAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTD 924 HSP 4 Score: 88.9669 bits (219), Expect = 1.003e-16 Identity = 57/171 (33.33%), Postives = 82/171 (47.95%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C +N C C N L F+C C G+ G CE +++EC+ N C D++ C+D + +FQC+C G CEV + C S C+H G C D + C C +G+ G C +D+C PC C D N + C C + +TG CE D C ++G C Sbjct: 416 CSLGANPCEHAGKC-INTLG-SFECQCLQGY--TGPRCEIDVNECVSNPCQNDAT-CLDQIGEFQCICMPGYEGVHCEV-NTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSC 580 HSP 5 Score: 84.7297 bits (208), Expect = 2.156e-15 Identity = 51/148 (34.46%), Postives = 70/148 (47.30%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 F C C PG+ G+ CE I+EC C + C D N + C C +G CE+ ++ C S C G C D C C G+ G CN +ID+C G+PC+ G CED +NGF C C + + C + C + G C Sbjct: 587 FTCLCRPGYTGH--HCETNINECSSQPCRHGGT-CQDRDNAYLCFCLKGTTGPNCEI-NLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGAC 730 HSP 6 Score: 84.3445 bits (207), Expect = 2.509e-15 Identity = 53/167 (31.74%), Postives = 83/167 (49.70%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLN 5682 C C+ +E + F C C G+ G +CE +I+EC+ + C +S C + ++C C + SGR CE ++ C + C +G C D + C CL G+ G C + I++C DPC C D ++ + C C F+GI CE + C S N G C++ Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGW--QGQTCEVDINECVLSPCRHGAS-CQNTHGGYRCHCQAGYSGRNCET-DIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 1000 HSP 7 Score: 82.0333 bits (201), Expect = 1.453e-14 Identity = 55/176 (31.25%), Postives = 82/176 (46.59%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTC--EVLKVNLCLKSDCVHGICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN-CSENFGVCLNLKNKNQYC 5706 C TC+ + +C C PGF G +CEE ID+C N C + C+D VN + C C + +G+ C +V + L + G C + + +C+C++GW G DC+++IDDC C C D + F C C TG+ C + N C+E N N C Sbjct: 227 CQNGGTCRPTG-DVTHECACLPGFTGQ--NCEENIDDCPGNNC-KNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAIC 398 HSP 8 Score: 79.7221 bits (195), Expect = 7.236e-14 Identity = 51/154 (33.12%), Postives = 72/154 (46.75%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI----CRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C A+C++ + ++C C G+ +G +CE +ID+C N C S C D +N C C G CE +N C C +G C D +C C +G+ GI C + DC C G C D +N F C C FTG +C+ D C Sbjct: 878 CRHGASCQNT--HGGYRCHCQAGY--SGRNCETDIDDCRPNPCHNGGS-CTDGINTAFCDCLPGFRGTFCEE-DINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNEC 1025 HSP 9 Score: 79.337 bits (194), Expect = 9.469e-14 Identity = 56/163 (34.36%), Postives = 80/163 (49.08%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE-----FDHFSCKN 5652 N CH +C ++ +N F C C PGF G+ CEE I+EC + C + + C D V+ + C C + SG CE + C +S C +G C D +CLC G+ G C +++C PC G C+D + C C Q +TG C+ D CKN Sbjct: 914 NPCHNGGSC-TDGINTAF-CDCLPGF--RGTFCEEDINECASDPCR-NGANCTDCVDSYTCTCPAGFSGIHCENNTPD-CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKN 1070 HSP 10 Score: 77.411 bits (189), Expect = 3.454e-13 Identity = 61/211 (28.91%), Postives = 88/211 (41.71%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCL---------------------GDSSR------------------CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDD----NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLN 5682 +N C TC L E++C C PG+ +G SC++ D C N C G + R C + V ++C+C + +G CE V C S C +G CR + C CL G+ G +C ++IDDC G+ C G C D +N + C C +TG +C D C+ N +N G C N Sbjct: 108 TNPCRNGGTCDLLTLT-EYKCRCPPGW--SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP-CSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHN 314 HSP 11 Score: 76.2554 bits (186), Expect = 7.298e-13 Identity = 50/166 (30.12%), Postives = 74/166 (44.58%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 S+ C A C + D + C C GF +G CE +C + C + C+D +N F CLC +G C+ VN C C+HG C+D C C G+ G +C + C PC G C + C C +TG++C+ SC+ ++ GV Sbjct: 951 SDPCRNGANC--TDCVDSYTCTCPAGF--SGIHCENNTPDCTESSCF-NGGTCVDGINSFTCLCPPGFTGSYCQ-HDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGV 1110 HSP 12 Score: 70.4774 bits (171), Expect = 4.408e-11 Identity = 53/156 (33.97%), Postives = 70/156 (44.87%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSR-CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS------CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEF 5631 S KC N TC + C C PGFVG CE +++ECL N C ++ C+ VNDF C C + +GR CE + +N C C +G C ++ C C +G+EG C C C G C C C FTG C+F Sbjct: 1235 SPKCFNNGTCVDQV--GGYSCTCPPGFVG--ERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESV-INGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQF 1385 HSP 13 Score: 70.0922 bits (170), Expect = 5.303e-11 Identity = 37/105 (35.24%), Postives = 56/105 (53.33%), Query Frame = 1 Query: 5344 CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C+D N C C + +G CE L V+ C S C +G C D SC C++G+ G++C++ ID+C+ PC G C D N + C+C + G+ CE + C Sbjct: 1122 CVDAGNTHHCRCQAGYTGSYCEDL-VDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDC 1225 HSP 14 Score: 64.6994 bits (156), Expect = 2.661e-9 Identity = 59/186 (31.72%), Postives = 79/186 (42.47%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSR---------CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKS--------DCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN---GFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLN 5682 S+ C TC +L + ++C C G G CE +D+C N + SR C+D V + C C G CE VN CL + +CV + +D C C +G G C I+ C G PC G C A N GFIC C F G CE D +C + N G C++ Sbjct: 1189 SHPCQNGGTCL--DLPNTYKCSCPRG--TQGVHCEINVDDC--NPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEG-DVNECLSNPCDARGTQNCVQRV--NDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCIS 1365 HSP 15 Score: 60.8474 bits (146), Expect = 3.660e-8 Identity = 46/146 (31.51%), Postives = 65/146 (44.52%), Query Frame = 1 Query: 5248 QCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIG--DP------CNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C C G+ GS CE+ +DEC + C + + C D + + C C + G C +++ CL C +G C D C C G +G+ C ++DDC DP C G C D + G+ C C F G CE D C Sbjct: 1130 HCRCQAGY--TGSYCEDLVDECSPSPC-QNGATCTDYLGGYSCKCVAGYHGVNCSE-EIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNEC 1271 HSP 16 Score: 59.3066 bits (142), Expect = 1.237e-7 Identity = 49/174 (28.16%), Postives = 68/174 (39.08%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCL-GDSSRCIDL--VNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD-----DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C C C++ N C C FVG C++ + CL C + +D V D+ C C SG C N CL + C +G D + C C GW G C ++ D C +PC G C +IC+C +F G C D C + G+C Sbjct: 24 CSQPGETCLNGGKCEA--ANGTEACVCGGAFVG--PRCQDPNPCLSTPCKNAGTCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA-DPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQD---VNECGQKPGLC 189
BLAST of Protocadherin Fat 4 vs. Ensembl Human
Match: NOTCH4 (notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]) HSP 1 Score: 95.1301 bits (235), Expect = 1.384e-18 Identity = 66/180 (36.67%), Postives = 85/180 (47.22%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK-NQYCLD 5712 S CH +TC +L F C C PG G CE E +EC CL + + C DL+N FQC+C SG CE ++ C S C +G C+D C CL G+EG C +D+C+ DPC C D F C C FTG CE N + +C + K+K N C D Sbjct: 480 SQPCHPGSTCL--DLLATFHCLCPPGL--EGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFSGTRCEE-DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVP-LCAPNLCQPKQICKDQKDKANCLCPD 652 HSP 2 Score: 88.9669 bits (219), Expect = 9.783e-17 Identity = 63/182 (34.62%), Postives = 81/182 (44.51%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSC-EEIDECLF-----NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVC 5676 +CH S CH +A C +N L C C PG+ +G +C +++DECL + C S C++ F CLC +G CE N CL C G C D CLC G EG C ++C PC C D LNGF C C F+G CE D C++ N G C Sbjct: 388 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPTCHQDLDECLMAQQGPSPCEHGGS-CLNTPGSFNCLCPPGYTGSRCEA-DHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQC 565 HSP 3 Score: 83.1889 bits (204), Expect = 6.195e-15 Identity = 62/202 (30.69%), Postives = 89/202 (44.06%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDE---FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEV--LKVNLCL----------KSDCV------------------HGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C + ++C + + D+ F C C PGF G C+ E+DECL + C +S C+DL F CLC S +G+ CEV NLC K++C+ HG C+ +SC+C GW G +C + CI PC G C +G+ C C +TG C + +C + G CLN Sbjct: 547 CEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGF--EGPRCQTEVDECLSDPCPVGAS-CLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQR-SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHS-----GPCLN 739 HSP 4 Score: 75.485 bits (184), Expect = 1.408e-12 Identity = 55/180 (30.56%), Postives = 83/180 (46.11%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNF--CLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-----ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS----ENFGVCLN 5682 ++N C C + + QC C PGF G +CE +++EC + C +S C + + FQCLC + G CE L+ C C +G + D++ CLC G+ G DC + D+C+ C G C+D L+ + C C + +TG C D C+ N G C N Sbjct: 160 SANPCVNGGVCLATY--PQIQCHCPPGF--EGHACERDVNECFQDPGPCPKGTS-CHNTLGSFQCLCPVGQEGPRCE-LRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQN 333 HSP 5 Score: 71.2478 bits (173), Expect = 2.378e-11 Identity = 48/155 (30.97%), Postives = 69/155 (44.52%), Query Frame = 1 Query: 5200 CHRNATCK-SNELNDEFQ-CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH----GICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 C TC+ E + F C C PGF+G CE D C+ + C + C D ++ + CLC +G C V+ C H G C++ C+C+SGW G C +++DDCI C C D + F C C TG+ C + Sbjct: 242 CSNGGTCQLMPEKDSTFHLCLCPPGFIG--PDCEVNPDNCVSHQC-QNGGTCQDGLDTYTCLCPETWTGWDCSE-DVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE 392 HSP 6 Score: 67.0106 bits (162), Expect = 4.749e-10 Identity = 50/181 (27.62%), Postives = 76/181 (41.99%), Query Frame = 1 Query: 5125 NLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCN--GRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 NLP+S GI + S+ CH C + + C C PGF GS C++ ++ C C + + C+ + + C C G+ C +++ C C HG C C C G+ G+ C +D+C+ PC+ G C N F C C TG +CE + C Sbjct: 879 NLPLSSCQKAALSQGIDV----SSLCHNGGLCVDS--GPSYFCHCPPGF--QGSLCQDHVNPCESRPC-QNGATCMAQPSGYLCQCAPGYDGQNCSK-ELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 1049 HSP 7 Score: 65.855 bits (159), Expect = 1.188e-9 Identity = 56/212 (26.42%), Postives = 76/212 (35.85%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG------------------------ICRDD--------------------------NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C TC+++ F C C G+ G+SCEE +D+C+ C S CID V F CLC R+G C + ++CL C HG C D +CLC G+ G C ++C+ PC+ C D L F C C G CE + C + CLN Sbjct: 325 CRNGGTCQNSA--GSFHCVCVSGW--GGTSCEENLDDCIAATC-APGSTCIDRVGSFSCLCPPGRTGLLCHL--EDMCLSQPC-HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAP-----CLN 523 HSP 8 Score: 63.5438 bits (153), Expect = 5.726e-9 Identity = 50/164 (30.49%), Postives = 69/164 (42.07%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNG-----SSCEE------IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C RN+ C + F C C G+ G SSC++ ID + + C + C+D + C C G C+ VN C C +G C S C C G++G +C+K +D C PC+ G C GF C C F G+ CE D C Sbjct: 852 CPRNSHCL--QTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID--VSSLC-HNGGLCVDSGPSYFCHCPPGFQGSLCQD-HVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC 1009 HSP 9 Score: 62.003 bits (149), Expect = 1.493e-8 Identity = 55/175 (31.43%), Postives = 68/175 (38.86%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-------VHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN---GFICNCQQNFTGIFCEFDHFSC--KNCSENFGVCL 5679 S C ATC + + C C PG+ G S +E+D C C + C F C C G CE V+ CL C H + + C CL G G C ID C PC G CE GFIC+C + F G C SC +C G+CL Sbjct: 935 SRPCQNGATCMAQP--SGYLCQCAPGYDGQNCS-KELDACQSQPC-HNHGTCTPKPGGFHCACPPGFVGLRCEG-DVDECLDQPCHPTGTAACHSLA-NAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHG-GLCL 1102 HSP 10 Score: 61.2326 bits (147), Expect = 3.130e-8 Identity = 48/173 (27.75%), Postives = 67/173 (38.73%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 ++ CH S C +C N + C C P G C+ D C+ C + C++ F CLC G CE C S C + C+D CLC +G+ G C +D C PC C F C C Q +TG C SC+ + + G+ Sbjct: 729 MTACH--SGPCLNGGSC--NPSPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCF-NGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGI 894 HSP 11 Score: 57.3806 bits (137), Expect = 4.173e-7 Identity = 48/175 (27.43%), Postives = 68/175 (38.86%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI-----------CRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC--EFDHFSCKNCSENFGVC 5676 C ATC+ + +C C G+ G GS +D C C +S C+ F CLC +G C L ++ C K+ GI C D C C G++G C ++ C PC C +G++C C + G C E D + C N G C Sbjct: 814 CRNRATCQDSPQGP--RCLCPTGYTG-GSCQTLMDLCAQKPC-PRNSHCLQTGPSFHCLCLQGWTGPLCN-LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPC-HNHGTC 982 HSP 12 Score: 54.299 bits (129), Expect = 3.330e-6 Identity = 55/188 (29.26%), Postives = 67/188 (35.64%), Query Frame = 1 Query: 5176 ICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVG----------------NGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCV-HGICRDDNS----CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 +C C TC S L + C C PGF+G NG SC+ L LG S L F C C +G C+ + C S C G C S C C+ GW G C D C +PC GVC C+C F G CE D C ++ G C Sbjct: 26 LCGSFPEPCANGGTCLSLSLG-QGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQ----ALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAQLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERD---VNECFQDPGPC 204 HSP 13 Score: 53.1434 bits (126), Expect = 7.038e-6 Identity = 45/168 (26.79%), Postives = 65/168 (38.69%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLN 5682 N C CK + D+ C C G G E+ C C S C+C +G CE ++ C+ + C HG C S C C +G+ G C++ + C PC G C + G+ C C + TG C+ C + N G C+N Sbjct: 631 NLCQPKQICKDQK--DKANCLCPDGSPGCAPP-EDNCTCHHGHCQRSS-----------CVCDVGWTGPECEA-ELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVN 783
BLAST of Protocadherin Fat 4 vs. Ensembl Human
Match: NOTCH4 (notch receptor 4 [Source:HGNC Symbol;Acc:HGNC:7884]) HSP 1 Score: 95.1301 bits (235), Expect = 1.384e-18 Identity = 66/180 (36.67%), Postives = 85/180 (47.22%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK-NQYCLD 5712 S CH +TC +L F C C PG G CE E +EC CL + + C DL+N FQC+C SG CE ++ C S C +G C+D C CL G+EG C +D+C+ DPC C D F C C FTG CE N + +C + K+K N C D Sbjct: 481 SQPCHPGSTCL--DLLATFHCLCPPGL--EGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFSGTRCEE-DIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVP-LCAPNLCQPKQICKDQKDKANCLCPD 653 HSP 2 Score: 88.9669 bits (219), Expect = 9.784e-17 Identity = 63/182 (34.62%), Postives = 81/182 (44.51%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSC-EEIDECLF-----NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVC 5676 +CH S CH +A C +N L C C PG+ +G +C +++DECL + C S C++ F CLC +G CE N CL C G C D CLC G EG C ++C PC C D LNGF C C F+G CE D C++ N G C Sbjct: 389 LCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY--SGPTCHQDLDECLMAQQGPSPCEHGGS-CLNTPGSFNCLCPPGYTGSRCEA-DHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQC 566 HSP 3 Score: 83.1889 bits (204), Expect = 6.196e-15 Identity = 62/202 (30.69%), Postives = 89/202 (44.06%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDE---FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEV--LKVNLCL----------KSDCV------------------HGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C + ++C + + D+ F C C PGF G C+ E+DECL + C +S C+DL F CLC S +G+ CEV NLC K++C+ HG C+ +SC+C GW G +C + CI PC G C +G+ C C +TG C + +C + G CLN Sbjct: 548 CEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGF--EGPRCQTEVDECLSDPCPVGAS-CLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQR-SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHS-----GPCLN 740 HSP 4 Score: 75.485 bits (184), Expect = 1.397e-12 Identity = 55/180 (30.56%), Postives = 83/180 (46.11%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNF--CLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-----ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS----ENFGVCLN 5682 ++N C C + + QC C PGF G +CE +++EC + C +S C + + FQCLC + G CE L+ C C +G + D++ CLC G+ G DC + D+C+ C G C+D L+ + C C + +TG C D C+ N G C N Sbjct: 161 SANPCVNGGVCLATY--PQIQCHCPPGF--EGHACERDVNECFQDPGPCPKGTS-CHNTLGSFQCLCPVGQEGPRCE-LRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQN 334 HSP 5 Score: 71.2478 bits (173), Expect = 2.358e-11 Identity = 48/155 (30.97%), Postives = 69/155 (44.52%), Query Frame = 1 Query: 5200 CHRNATCK-SNELNDEFQ-CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH----GICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 C TC+ E + F C C PGF+G CE D C+ + C + C D ++ + CLC +G C V+ C H G C++ C+C+SGW G C +++DDCI C C D + F C C TG+ C + Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIG--PDCEVNPDNCVSHQC-QNGGTCQDGLDTYTCLCPETWTGWDCSE-DVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE 393 HSP 6 Score: 67.0106 bits (162), Expect = 4.750e-10 Identity = 50/181 (27.62%), Postives = 76/181 (41.99%), Query Frame = 1 Query: 5125 NLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCN--GRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 NLP+S GI + S+ CH C + + C C PGF GS C++ ++ C C + + C+ + + C C G+ C +++ C C HG C C C G+ G+ C +D+C+ PC+ G C N F C C TG +CE + C Sbjct: 880 NLPLSSCQKAALSQGIDV----SSLCHNGGLCVDS--GPSYFCHCPPGF--QGSLCQDHVNPCESRPC-QNGATCMAQPSGYLCQCAPGYDGQNCSK-ELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPC 1050 HSP 7 Score: 65.855 bits (159), Expect = 1.188e-9 Identity = 56/212 (26.42%), Postives = 76/212 (35.85%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG------------------------ICRDD--------------------------NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C TC+++ F C C G+ G+SCEE +D+C+ C S CID V F CLC R+G C + ++CL C HG C D +CLC G+ G C ++C+ PC+ C D L F C C G CE + C + CLN Sbjct: 326 CRNGGTCQNSA--GSFHCVCVSGW--GGTSCEENLDDCIAATC-APGSTCIDRVGSFSCLCPPGRTGLLCHL--EDMCLSQPC-HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAP-----CLN 524 HSP 8 Score: 63.5438 bits (153), Expect = 5.726e-9 Identity = 50/164 (30.49%), Postives = 69/164 (42.07%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNG-----SSCEE------IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C RN+ C + F C C G+ G SSC++ ID + + C + C+D + C C G C+ VN C C +G C S C C G++G +C+K +D C PC+ G C GF C C F G+ CE D C Sbjct: 853 CPRNSHCL--QTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID--VSSLC-HNGGLCVDSGPSYFCHCPPGFQGSLCQD-HVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC 1010 HSP 9 Score: 62.003 bits (149), Expect = 1.494e-8 Identity = 55/175 (31.43%), Postives = 68/175 (38.86%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-------VHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN---GFICNCQQNFTGIFCEFDHFSC--KNCSENFGVCL 5679 S C ATC + + C C PG+ G S +E+D C C + C F C C G CE V+ CL C H + + C CL G G C ID C PC G CE GFIC+C + F G C SC +C G+CL Sbjct: 936 SRPCQNGATCMAQP--SGYLCQCAPGYDGQNCS-KELDACQSQPC-HNHGTCTPKPGGFHCACPPGFVGLRCEG-DVDECLDQPCHPTGTAACHSLA-NAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHG-GLCL 1103 HSP 10 Score: 57.7658 bits (138), Expect = 3.354e-7 Identity = 47/173 (27.17%), Postives = 66/173 (38.15%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 ++ CH S C +C N + C C P G C+ D C+ C + C++ F CLC G CE C S C + C+D CLC + + G C +D C PC C F C C Q +TG C SC+ + + G+ Sbjct: 730 MTACH--SGPCLNGGSC--NPSPGGYYCTCPPSH--TGPQCQTSTDYCVSAPCF-NGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTVYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGI 895 HSP 11 Score: 54.299 bits (129), Expect = 3.623e-6 Identity = 55/188 (29.26%), Postives = 67/188 (35.64%), Query Frame = 1 Query: 5176 ICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVG----------------NGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCV-HGICRDDNS----CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 +C C TC S L + C C PGF+G NG SC+ L LG S L F C C +G C+ + C S C G C S C C+ GW G C D C +PC GVC C+C F G CE D C ++ G C Sbjct: 27 LCGSFPEPCANGGTCLSLSLG-QGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQ----ALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERD---VNECFQDPGPC 205 HSP 12 Score: 53.9138 bits (128), Expect = 4.470e-6 Identity = 47/175 (26.86%), Postives = 67/175 (38.29%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI-----------CRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC--EFDHFSCKNCSENFGVC 5676 C ATC+ + +C C + G GS +D C C +S C+ F CLC +G C L ++ C K+ GI C D C C G++G C ++ C PC C +G++C C + G C E D + C N G C Sbjct: 815 CRNRATCQDSPQGP--RCLCPTVYTG-GSCQTLMDLCAQKPC-PRNSHCLQTGPSFHCLCLQGWTGPLCN-LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPC-HNHGTC 983 HSP 13 Score: 53.1434 bits (126), Expect = 7.039e-6 Identity = 45/168 (26.79%), Postives = 65/168 (38.69%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLN 5682 N C CK + D+ C C G G E+ C C S C+C +G CE ++ C+ + C HG C S C C +G+ G C++ + C PC G C + G+ C C + TG C+ C + N G C+N Sbjct: 632 NLCQPKQICKDQK--DKANCLCPDGSPGCAPP-EDNCTCHHGHCQRSS-----------CVCDVGWTGPECEA-ELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVN 784
BLAST of Protocadherin Fat 4 vs. Ensembl Celegans
Match: clec-78 (C-type LECtin [Source:UniProtKB/TrEMBL;Acc:Q20531]) HSP 1 Score: 112.464 bits (280), Expect = 3.273e-24 Identity = 66/176 (37.50%), Postives = 99/176 (56.25%), Query Frame = 1 Query: 5176 ICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEF--DHFSCKNCSENFGVCLNL 5685 IC N N C A C +L F+C C PG+ G +C++ ID+C + C +++ C+DL+ND++C C + SG+ C + K NLC S CVHG+C D CLC GW G +C+++ID+C PC C D +NG++C C + G+ C+ DH + + C N C N+ Sbjct: 2132 ICSTN-NPCRNGARCIGEKLG-RFKCQCVPGW--EGPNCDKNIDDCADSPCALNAT-CVDLINDYKCECPTGFSGKRCHI-KENLCASSPCVHGLCIDKLYSRQCLCQPGWTGENCDQNIDECAASPCQNDAKCIDEINGYMCECADGYEGVHCQHLVDHCAKQPCHNN-ATCTNM 2300 HSP 2 Score: 87.8113 bits (216), Expect = 9.041e-17 Identity = 56/174 (32.18%), Postives = 85/174 (48.85%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQYC 5706 N+C + T + ++F+C C PG+ G ++ D+C + CL D+ +C+D+ ++C+C S +G CE + K +G C D C+C G G +C + + CIG PC+ G C D + C C +FTG CEF + CK C EN G C Q C Sbjct: 2327 NQCDKLGTESCRDAVNDFKCVCKPGYTGPRCDVKQ-DQCADSPCLNDA-QCVDMGGAYKCVCKSGWTGPKCEQDNGSCAAKPCRNNGFCVSLVADYFCVCPPGVSGKNCESAPNRCIGQPCHNGGECGDFGSHLECACPASFTGKGCEFKNTGCKTC-ENGGKCAEAAGGLQKC 2497 HSP 3 Score: 73.9442 bits (180), Expect = 1.786e-12 Identity = 54/168 (32.14%), Postives = 83/168 (49.40%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEF---QCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGV--CEDALNGFICNCQQNFTGIFCEFDHFSCKN 5652 CH N C ++ C D+ QC C PG+ G +C++ IDEC + C D+ +CID +N + C C G C+ L V+ C K C + C + + C C G++G+ C +ID+C + C+ G C DA+N F C C+ +TG C+ C + Sbjct: 2204 CHIKENLC-ASSPCVHGLCIDKLYSRQCLCQPGWTGE--NCDQNIDECAASPCQNDA-KCIDEINGYMCECADGYEGVHCQHL-VDHCAKQPCHNNATCTNMGATYHCDCTLGFDGVHCEMNIDECAENQCDKLGTESCRDAVNDFKCVCKPGYTGPRCDVKQDQCAD 2366 HSP 4 Score: 67.0106 bits (162), Expect = 1.917e-10 Identity = 51/173 (29.48%), Postives = 79/173 (45.66%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDL--VNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI-CRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 ++ C+ C+ ++ ++C C F NG+ C+ E DEC C + C DL V CLC + +G CE + + C +G C + C C+ GWEG +C+K+IDDC PC C D +N + C C F+G C C + G+C++ Sbjct: 2056 STQPCYNGGKCE--QVGTTYKCTCPKMF--NGARCQFESDECNGVKCP-NGGVCHDLPGVKSTTCLCRTGFAGPQCEEITDICSTNNPCRNGARCIGEKLGRFKCQCVPGWEGPNCDKNIDDCADSPCALNATCVDLINDYKCECPTGFSGKRCHIKENLCASSPCVHGLCID 2223 HSP 5 Score: 53.5286 bits (127), Expect = 2.400e-6 Identity = 45/154 (29.22%), Postives = 65/154 (42.21%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLG----DSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD----NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 + C N C S L ++ C C PG +G +CE N C+G + C D + +C C + +G+ CE N K+ G C + C C G+ G C +ID+C C C D +N IC C N TG+ C+ Sbjct: 2404 AKPCRNNGFCVS--LVADYFCVCPPGV--SGKNCESAP----NRCIGQPCHNGGECGDFGSHLECACPASFTGKGCEFK--NTGCKTCENGGKCAEAAGGLQKCECSPGFTGERCETNIDECSTAHCPSGATCVDQVNTHICVCPFNLTGVHCD 2547
BLAST of Protocadherin Fat 4 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 77.7962 bits (190), Expect = 1.088e-13 Identity = 141/561 (25.13%), Postives = 239/561 (42.60%), Query Frame = 1 Query: 133 ESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND-PPTNIQLSNW-KVEENILVGSLVGQISVVDEDLDDS--FKCSVKSDSPFNVDANFNLF-TKAPLDYETQARFEVIIECLDHENSSVINKHEISVT--DINE-AP---DKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINE----LYSF---QILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLI--DVNE-APQ-GLTLYPSTVTENIPSGSV----------IGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPENLSLSNN-QIPENEPIGLLIAIINAQDNDK--NSTLVYTL--DVNEKDFYIENN-------KLLSGTVFDHENR 1680 ++K + I+ I AKD P S + + ++D ND PT I +EEN+ +G VG++ +DED + K S++ F +D + L T LD ET AR+ + + D S+ I+V DIN+ AP K Y T +EEM G++I + D D + + + D + + E++ Q ++ +IS TD+ +V + I +V+ P ND + + E + Y + L A D D + +YS Q + S + I S++L+ E +V A N + I++I D+N+ +PQ + Y +T++E+IP G+ IG I+D LN + S+QL F + + L+ +++LD E+ L I D G ++ EI L +SD N+ P LS + I EN P+G + I A+D D+ N+ + + + + K F IE + ++L+ FD+E + Sbjct: 80 DAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEM--------PRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQ---------DHKVRVEISATDQGGLQGRCVVNVFIDDVNSAP---YFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQFFRIDPSSGD--------ISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQL------FRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAK 606 HSP 2 Score: 52.373 bits (124), Expect = 5.589e-6 Identity = 82/331 (24.77%), Postives = 141/331 (42.60%), Query Frame = 1 Query: 1156 IQLIDVNE-APQGLT-LYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI--FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIP--ENEPIGLLIAIINA--QDNDKNSTLVYTLDVNEKDFYI-ENNKLLSGT-VFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQI-ISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPP 2115 I ++DVN+ AP + Y T+ ENI +VI D + T K + + + I I E+ R+D + +P + IR D Q + + + + + D N+ L + I EN IG + + A +D+ N + Y+++ +E DF I E++ L+ T + D E Y + +T D G P LN S T + + + N+N K +Y N T I E T+ + D D KI +I +D F + + I L+++ L Q++ + I D + +F+++VN P Sbjct: 4 ITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFG-TNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAV-IRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSE-DFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEY-NVT----ISEEMPRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAI----LSVSGELK-RQDHKVRVEISATDQGGLQGRCVVNVFIDDVNSAP 321
BLAST of Protocadherin Fat 4 vs. Ensembl Celegans
Match: slt-1 (Slit homolog 1 protein [Source:UniProtKB/Swiss-Prot;Acc:G5EFX6]) HSP 1 Score: 77.411 bits (189), Expect = 1.148e-13 Identity = 54/151 (35.76%), Postives = 79/151 (52.32%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKS--DCVH-GICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEF 5631 C NATCK + F C+CN GF G CE+ ID+C+ + C + +C+DL+N ++C C + G+ CE K+ C K C + G C N SC+C G+ G +C +IDDC C G C D + + C C+ + G +CE Sbjct: 917 CLNNATCKVAQAG-RFNCYCNKGF--EGDYCEKNIDDCVNSKC-ENGGKCVDLINSYRCDCPMEYEGKHCED-KLEYCTKKLNPCENNGKCIPINGSYSCMCSPGFTGNNCETNIDDCKNVECQNGGSCVDGILSYDCLCRPGYAGQYCEI 1062 HSP 2 Score: 56.6102 bits (135), Expect = 2.428e-7 Identity = 47/164 (28.66%), Postives = 68/164 (41.46%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCL 5679 C NA C++ + ++ C C PGF G CE +ID C + CL +++ C ++GR +C C G+EG C K+IDDC+ C G C D +N + C+C + G CE C N EN G C+ Sbjct: 878 CKNNAICETTS-SRKYTCNCTPGFYG--VHCENQIDACYGSPCLNNAT------------CKVAQAGRF-----------------------NCYCNKGFEGDYCEKNIDDCVNSKCENGGKCVDLINSYRCDCPMEYEGKHCEDKLEYCTKKLNPCENNGKCI 1003 HSP 3 Score: 54.299 bits (129), Expect = 1.224e-6 Identity = 41/139 (29.50%), Postives = 61/139 (43.88%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEV--------LKVNLCLKSDCVHGIC-----RDDNSCLCLSGWEGIDCNKSIDDCIGDP 5544 + C N C N C +N + C C+PGF GN +CE ID+C C S C+D + + CLC +G+ CE+ K + C +S C G C D +C C G+ G C++ + +P Sbjct: 986 LEYCTKKLNPCENNGKCIP--INGSYSCMCSPGFTGN--NCETNIDDCKNVECQNGGS-CVDGILSYDCLCRPGYAGQYCEIPPMMDMEYQKTDACQQSACGQGECVASQNSSDFTCKCHEGFSGPSCDRQMSVGFKNP 1119
BLAST of Protocadherin Fat 4 vs. Ensembl Celegans
Match: egas-1 (EGF plus ASC domain ion channel [Source:UniProtKB/TrEMBL;Acc:Q9U1T9]) HSP 1 Score: 66.6254 bits (161), Expect = 1.857e-10 Identity = 49/149 (32.89%), Postives = 71/149 (47.65%), Query Frame = 1 Query: 5209 NATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVN-DFQCLCGSDRSGRTCEVLKVNLC-LKSDCVHGICRD-------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 N TC N+ ++F C C+ GF G+ C+ D C CL + C +L N D++C C G+ CEV +N C C +G C + +C C GW G +C+ ID CI +PC+ C+ G+ C C TG+ C Sbjct: 369 NGTCVLNDQYNKFTCVCDDGFFGD--KCQYSDICTSATCLYGGT-CTELNNGDYKCDCLLQYFGKNCEV--INRCDYGKPCNNGKCASTIDGITTNYTCTCDDGWTGTNCDTMIDFCIPNPCSYNSTCKPKFKGYDCTCITGLTGVNCS 512
BLAST of Protocadherin Fat 4 vs. Ensembl Celegans
Match: egas-3 (EGF plus ASC domain ion channel [Source:UniProtKB/TrEMBL;Acc:Q9XTS9]) HSP 1 Score: 65.0846 bits (157), Expect = 5.310e-10 Identity = 50/148 (33.78%), Postives = 68/148 (45.95%), Query Frame = 1 Query: 5209 NATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVND-FQCLCGSDRSGRTCEVLKVNLCLKSD-CVHGICRD-------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC 5625 N TC NE ++++C C+ GF G+ +CE C CL + C + N F+C C + SG CE ++N C D CV+G C + +C C GW G +C ID C DPC C G+ C C TG C Sbjct: 368 NGTCVLNEQYNKYKCDCDDGFSGD--NCEYSKTCTAATCLYGGT-CTETNNGGFKCDCLNLYSGNRCE--EINRCNYGDPCVNGKCETTVDGITTNYTCTCDDGWTGANCETMIDFCTPDPCKYNSTCTPKFKGYDCTCLTGLTGANC 510
BLAST of Protocadherin Fat 4 vs. Ensembl Fly
Match: uif (gene:FBgn0031879 transcript:FBtr0307072) HSP 1 Score: 123.25 bits (308), Expect = 2.168e-27 Identity = 68/171 (39.77%), Postives = 96/171 (56.14%), Query Frame = 1 Query: 5164 VGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSEN 5664 V I C N N C A+C++ E ++C C PG+ G CE+ I++C N CL ++ C DLVNDFQC C +G+ CE K++LCL C HG C D D+ C+C GW G C+ +IDDC PC G C D ++G+ CNC+ +TG C+ + +C+ N Sbjct: 2136 VTIDPCTANGNPCGNGASCQALE-QGRYKCECVPGW--EGIHCEQNINDCSENPCLLGAN-CTDLVNDFQCACPPGFTGKRCE-QKIDLCLSEPCKHGTCVDRLFDHECVCHPGWTGSACDINIDDCENRPCANEGTCVDLVDGYSCNCEPGYTGKNCQ---HTIDDCASN 2298 HSP 2 Score: 96.6709 bits (239), Expect = 2.301e-19 Identity = 67/211 (31.75%), Postives = 99/211 (46.92%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFC--LGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD------------------------------------------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 SN C ATC D F C C PG+VG SCE EIDECL + C +G + RC+DL N F+C+C G C ++ C C++ GICRD D C+C SG +G +C + + CIGDPC G C+D +G C+C +++GI C++++ +C ++ +N C++ Sbjct: 2297 SNPCQHGATCVDQL--DGFSCKCRPGYVG--LSCEAEIDECLSDPCNPVG-TERCLDLDNKFECVCRDGFKGPLCAT-DIDDCEAQPCLNNGICRDRVGGFECGCEPGWSGMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAPERCIGDPCMHGGKCQDFGSGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVD 2501 HSP 3 Score: 82.0333 bits (201), Expect = 7.100e-15 Identity = 56/173 (32.37%), Postives = 77/173 (44.51%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFG-VCLNLKN 5691 + C N C+ F+C C PG+ +G CE+ + C + + CIDL D+ C+C S G+ CE C+ C+HG C+D S C C + + GI C D C C C D G+ C C FTG CE D CK+ S G C++L N Sbjct: 2375 AQPCLNNGICRDRV--GGFECGCEPGW--SGMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAP-ERCIGDPCMHGGKCQDFGSGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDIVDCKDNSCPPGATCVDLTN 2542 HSP 4 Score: 75.485 bits (184), Expect = 6.952e-13 Identity = 59/194 (30.41%), Postives = 90/194 (46.39%), Query Frame = 1 Query: 5113 DQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRDDN-----SCLCLSGWEGIDCNKSIDDCI--GDPCNGRGVCEDALNG-FICNCQQNFTGIFCEFDHFSCKNCSEN 5664 + T+ P SKG + + V +C C C + + QCFC GF +G CE+ IDEC C + +C DL ++C C + SG C+ + + C C +C+++ +CLC SG+ G C+ +ID C G+PC C+ G + C C + GI CE + +CSEN Sbjct: 2006 NMRTDSPASKGREQCKPV---VC--GEGACQHGGLCVP--MGHDIQCFCPAGF--SGRRCEQDIDECASQPCY-NGGQCKDLPQGYRCECPAGYSGINCQE-EASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCDVTIDPCTANGNPCGNGASCQALEQGRYKCECVPGWEGIHCEQN---INDCSEN 2185 HSP 5 Score: 69.3218 bits (168), Expect = 4.625e-11 Identity = 47/147 (31.97%), Postives = 69/147 (46.94%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDE-CLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC 5625 C +A+C +L ++ C C G +G +CE E C+ + C+ +C D + C C +D SG C+ + + C + C +G DN SC C G+ G +C + I DC + C C D NGF C C N TG C Sbjct: 2417 CQNDASCI--DLFQDYFCVCPSG--TDGKNCETAPERCIGDPCM-HGGKCQDFGSGLNCSCPADYSGIGCQ-YEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDIVDCKDNSCPPGATCVDLTNGFYCQCPFNMTGDDC 2557 HSP 6 Score: 61.6178 bits (148), Expect = 1.159e-8 Identity = 37/119 (31.09%), Postives = 55/119 (46.22%), Query Frame = 1 Query: 5344 CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVC--EDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C+ + +D QC C + SGR CE ++ C C +G C+D C C +G+ GI+C + DC D C R +C E C C+ +TG C+ + C+ N C N Sbjct: 2036 CVPMGHDIQCFCPAGFSGRRCE-QDIDECASQPCYNGGQCKDLPQGYRCECPAGYSGINCQEEASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCD---VTIDPCTANGNPCGN 2150
BLAST of Protocadherin Fat 4 vs. Ensembl Fly
Match: uif (gene:FBgn0031879 transcript:FBtr0302162) HSP 1 Score: 123.25 bits (308), Expect = 2.168e-27 Identity = 68/171 (39.77%), Postives = 96/171 (56.14%), Query Frame = 1 Query: 5164 VGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSEN 5664 V I C N N C A+C++ E ++C C PG+ G CE+ I++C N CL ++ C DLVNDFQC C +G+ CE K++LCL C HG C D D+ C+C GW G C+ +IDDC PC G C D ++G+ CNC+ +TG C+ + +C+ N Sbjct: 2136 VTIDPCTANGNPCGNGASCQALE-QGRYKCECVPGW--EGIHCEQNINDCSENPCLLGAN-CTDLVNDFQCACPPGFTGKRCE-QKIDLCLSEPCKHGTCVDRLFDHECVCHPGWTGSACDINIDDCENRPCANEGTCVDLVDGYSCNCEPGYTGKNCQ---HTIDDCASN 2298 HSP 2 Score: 96.6709 bits (239), Expect = 2.301e-19 Identity = 67/211 (31.75%), Postives = 99/211 (46.92%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFC--LGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD------------------------------------------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 SN C ATC D F C C PG+VG SCE EIDECL + C +G + RC+DL N F+C+C G C ++ C C++ GICRD D C+C SG +G +C + + CIGDPC G C+D +G C+C +++GI C++++ +C ++ +N C++ Sbjct: 2297 SNPCQHGATCVDQL--DGFSCKCRPGYVG--LSCEAEIDECLSDPCNPVG-TERCLDLDNKFECVCRDGFKGPLCAT-DIDDCEAQPCLNNGICRDRVGGFECGCEPGWSGMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAPERCIGDPCMHGGKCQDFGSGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVD 2501 HSP 3 Score: 82.0333 bits (201), Expect = 7.100e-15 Identity = 56/173 (32.37%), Postives = 77/173 (44.51%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFG-VCLNLKN 5691 + C N C+ F+C C PG+ +G CE+ + C + + CIDL D+ C+C S G+ CE C+ C+HG C+D S C C + + GI C D C C C D G+ C C FTG CE D CK+ S G C++L N Sbjct: 2375 AQPCLNNGICRDRV--GGFECGCEPGW--SGMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAP-ERCIGDPCMHGGKCQDFGSGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDIVDCKDNSCPPGATCVDLTN 2542 HSP 4 Score: 75.485 bits (184), Expect = 6.952e-13 Identity = 59/194 (30.41%), Postives = 90/194 (46.39%), Query Frame = 1 Query: 5113 DQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRDDN-----SCLCLSGWEGIDCNKSIDDCI--GDPCNGRGVCEDALNG-FICNCQQNFTGIFCEFDHFSCKNCSEN 5664 + T+ P SKG + + V +C C C + + QCFC GF +G CE+ IDEC C + +C DL ++C C + SG C+ + + C C +C+++ +CLC SG+ G C+ +ID C G+PC C+ G + C C + GI CE + +CSEN Sbjct: 2006 NMRTDSPASKGREQCKPV---VC--GEGACQHGGLCVP--MGHDIQCFCPAGF--SGRRCEQDIDECASQPCY-NGGQCKDLPQGYRCECPAGYSGINCQE-EASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCDVTIDPCTANGNPCGNGASCQALEQGRYKCECVPGWEGIHCEQN---INDCSEN 2185 HSP 5 Score: 69.3218 bits (168), Expect = 4.625e-11 Identity = 47/147 (31.97%), Postives = 69/147 (46.94%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDE-CLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC 5625 C +A+C +L ++ C C G +G +CE E C+ + C+ +C D + C C +D SG C+ + + C + C +G DN SC C G+ G +C + I DC + C C D NGF C C N TG C Sbjct: 2417 CQNDASCI--DLFQDYFCVCPSG--TDGKNCETAPERCIGDPCM-HGGKCQDFGSGLNCSCPADYSGIGCQ-YEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDIVDCKDNSCPPGATCVDLTNGFYCQCPFNMTGDDC 2557 HSP 6 Score: 61.6178 bits (148), Expect = 1.159e-8 Identity = 37/119 (31.09%), Postives = 55/119 (46.22%), Query Frame = 1 Query: 5344 CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVC--EDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C+ + +D QC C + SGR CE ++ C C +G C+D C C +G+ GI+C + DC D C R +C E C C+ +TG C+ + C+ N C N Sbjct: 2036 CVPMGHDIQCFCPAGFSGRRCE-QDIDECASQPCYNGGQCKDLPQGYRCECPAGYSGINCQEEASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCD---VTIDPCTANGNPCGN 2150
BLAST of Protocadherin Fat 4 vs. Ensembl Fly
Match: uif (gene:FBgn0031879 transcript:FBtr0307074) HSP 1 Score: 123.25 bits (308), Expect = 2.168e-27 Identity = 68/171 (39.77%), Postives = 96/171 (56.14%), Query Frame = 1 Query: 5164 VGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSEN 5664 V I C N N C A+C++ E ++C C PG+ G CE+ I++C N CL ++ C DLVNDFQC C +G+ CE K++LCL C HG C D D+ C+C GW G C+ +IDDC PC G C D ++G+ CNC+ +TG C+ + +C+ N Sbjct: 2136 VTIDPCTANGNPCGNGASCQALE-QGRYKCECVPGW--EGIHCEQNINDCSENPCLLGAN-CTDLVNDFQCACPPGFTGKRCE-QKIDLCLSEPCKHGTCVDRLFDHECVCHPGWTGSACDINIDDCENRPCANEGTCVDLVDGYSCNCEPGYTGKNCQ---HTIDDCASN 2298 HSP 2 Score: 96.6709 bits (239), Expect = 2.301e-19 Identity = 67/211 (31.75%), Postives = 99/211 (46.92%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFC--LGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD------------------------------------------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 SN C ATC D F C C PG+VG SCE EIDECL + C +G + RC+DL N F+C+C G C ++ C C++ GICRD D C+C SG +G +C + + CIGDPC G C+D +G C+C +++GI C++++ +C ++ +N C++ Sbjct: 2297 SNPCQHGATCVDQL--DGFSCKCRPGYVG--LSCEAEIDECLSDPCNPVG-TERCLDLDNKFECVCRDGFKGPLCAT-DIDDCEAQPCLNNGICRDRVGGFECGCEPGWSGMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAPERCIGDPCMHGGKCQDFGSGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVD 2501 HSP 3 Score: 82.0333 bits (201), Expect = 7.100e-15 Identity = 56/173 (32.37%), Postives = 77/173 (44.51%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFG-VCLNLKN 5691 + C N C+ F+C C PG+ +G CE+ + C + + CIDL D+ C+C S G+ CE C+ C+HG C+D S C C + + GI C D C C C D G+ C C FTG CE D CK+ S G C++L N Sbjct: 2375 AQPCLNNGICRDRV--GGFECGCEPGW--SGMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAP-ERCIGDPCMHGGKCQDFGSGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDIVDCKDNSCPPGATCVDLTN 2542 HSP 4 Score: 75.485 bits (184), Expect = 6.952e-13 Identity = 59/194 (30.41%), Postives = 90/194 (46.39%), Query Frame = 1 Query: 5113 DQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRDDN-----SCLCLSGWEGIDCNKSIDDCI--GDPCNGRGVCEDALNG-FICNCQQNFTGIFCEFDHFSCKNCSEN 5664 + T+ P SKG + + V +C C C + + QCFC GF +G CE+ IDEC C + +C DL ++C C + SG C+ + + C C +C+++ +CLC SG+ G C+ +ID C G+PC C+ G + C C + GI CE + +CSEN Sbjct: 2006 NMRTDSPASKGREQCKPV---VC--GEGACQHGGLCVP--MGHDIQCFCPAGF--SGRRCEQDIDECASQPCY-NGGQCKDLPQGYRCECPAGYSGINCQE-EASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCDVTIDPCTANGNPCGNGASCQALEQGRYKCECVPGWEGIHCEQN---INDCSEN 2185 HSP 5 Score: 69.3218 bits (168), Expect = 4.625e-11 Identity = 47/147 (31.97%), Postives = 69/147 (46.94%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDE-CLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC 5625 C +A+C +L ++ C C G +G +CE E C+ + C+ +C D + C C +D SG C+ + + C + C +G DN SC C G+ G +C + I DC + C C D NGF C C N TG C Sbjct: 2417 CQNDASCI--DLFQDYFCVCPSG--TDGKNCETAPERCIGDPCM-HGGKCQDFGSGLNCSCPADYSGIGCQ-YEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDIVDCKDNSCPPGATCVDLTNGFYCQCPFNMTGDDC 2557 HSP 6 Score: 61.6178 bits (148), Expect = 1.159e-8 Identity = 37/119 (31.09%), Postives = 55/119 (46.22%), Query Frame = 1 Query: 5344 CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVC--EDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C+ + +D QC C + SGR CE ++ C C +G C+D C C +G+ GI+C + DC D C R +C E C C+ +TG C+ + C+ N C N Sbjct: 2036 CVPMGHDIQCFCPAGFSGRRCE-QDIDECASQPCYNGGQCKDLPQGYRCECPAGYSGINCQEEASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCD---VTIDPCTANGNPCGN 2150
BLAST of Protocadherin Fat 4 vs. Ensembl Fly
Match: uif (gene:FBgn0031879 transcript:FBtr0307073) HSP 1 Score: 123.25 bits (308), Expect = 2.168e-27 Identity = 68/171 (39.77%), Postives = 96/171 (56.14%), Query Frame = 1 Query: 5164 VGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSEN 5664 V I C N N C A+C++ E ++C C PG+ G CE+ I++C N CL ++ C DLVNDFQC C +G+ CE K++LCL C HG C D D+ C+C GW G C+ +IDDC PC G C D ++G+ CNC+ +TG C+ + +C+ N Sbjct: 2136 VTIDPCTANGNPCGNGASCQALE-QGRYKCECVPGW--EGIHCEQNINDCSENPCLLGAN-CTDLVNDFQCACPPGFTGKRCE-QKIDLCLSEPCKHGTCVDRLFDHECVCHPGWTGSACDINIDDCENRPCANEGTCVDLVDGYSCNCEPGYTGKNCQ---HTIDDCASN 2298 HSP 2 Score: 96.6709 bits (239), Expect = 2.301e-19 Identity = 67/211 (31.75%), Postives = 99/211 (46.92%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFC--LGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD------------------------------------------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 SN C ATC D F C C PG+VG SCE EIDECL + C +G + RC+DL N F+C+C G C ++ C C++ GICRD D C+C SG +G +C + + CIGDPC G C+D +G C+C +++GI C++++ +C ++ +N C++ Sbjct: 2297 SNPCQHGATCVDQL--DGFSCKCRPGYVG--LSCEAEIDECLSDPCNPVG-TERCLDLDNKFECVCRDGFKGPLCAT-DIDDCEAQPCLNNGICRDRVGGFECGCEPGWSGMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAPERCIGDPCMHGGKCQDFGSGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVD 2501 HSP 3 Score: 82.0333 bits (201), Expect = 7.100e-15 Identity = 56/173 (32.37%), Postives = 77/173 (44.51%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFG-VCLNLKN 5691 + C N C+ F+C C PG+ +G CE+ + C + + CIDL D+ C+C S G+ CE C+ C+HG C+D S C C + + GI C D C C C D G+ C C FTG CE D CK+ S G C++L N Sbjct: 2375 AQPCLNNGICRDRV--GGFECGCEPGW--SGMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAP-ERCIGDPCMHGGKCQDFGSGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDIVDCKDNSCPPGATCVDLTN 2542 HSP 4 Score: 75.485 bits (184), Expect = 6.952e-13 Identity = 59/194 (30.41%), Postives = 90/194 (46.39%), Query Frame = 1 Query: 5113 DQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRDDN-----SCLCLSGWEGIDCNKSIDDCI--GDPCNGRGVCEDALNG-FICNCQQNFTGIFCEFDHFSCKNCSEN 5664 + T+ P SKG + + V +C C C + + QCFC GF +G CE+ IDEC C + +C DL ++C C + SG C+ + + C C +C+++ +CLC SG+ G C+ +ID C G+PC C+ G + C C + GI CE + +CSEN Sbjct: 2006 NMRTDSPASKGREQCKPV---VC--GEGACQHGGLCVP--MGHDIQCFCPAGF--SGRRCEQDIDECASQPCY-NGGQCKDLPQGYRCECPAGYSGINCQE-EASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCDVTIDPCTANGNPCGNGASCQALEQGRYKCECVPGWEGIHCEQN---INDCSEN 2185 HSP 5 Score: 69.3218 bits (168), Expect = 4.625e-11 Identity = 47/147 (31.97%), Postives = 69/147 (46.94%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDE-CLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC 5625 C +A+C +L ++ C C G +G +CE E C+ + C+ +C D + C C +D SG C+ + + C + C +G DN SC C G+ G +C + I DC + C C D NGF C C N TG C Sbjct: 2417 CQNDASCI--DLFQDYFCVCPSG--TDGKNCETAPERCIGDPCM-HGGKCQDFGSGLNCSCPADYSGIGCQ-YEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDIVDCKDNSCPPGATCVDLTNGFYCQCPFNMTGDDC 2557 HSP 6 Score: 61.6178 bits (148), Expect = 1.159e-8 Identity = 37/119 (31.09%), Postives = 55/119 (46.22%), Query Frame = 1 Query: 5344 CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVC--EDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C+ + +D QC C + SGR CE ++ C C +G C+D C C +G+ GI+C + DC D C R +C E C C+ +TG C+ + C+ N C N Sbjct: 2036 CVPMGHDIQCFCPAGFSGRRCE-QDIDECASQPCYNGGQCKDLPQGYRCECPAGYSGINCQEEASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCD---VTIDPCTANGNPCGN 2150
BLAST of Protocadherin Fat 4 vs. Ensembl Fly
Match: uif (gene:FBgn0031879 transcript:FBtr0339664) HSP 1 Score: 123.25 bits (308), Expect = 2.239e-27 Identity = 68/171 (39.77%), Postives = 96/171 (56.14%), Query Frame = 1 Query: 5164 VGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSEN 5664 V I C N N C A+C++ E ++C C PG+ G CE+ I++C N CL ++ C DLVNDFQC C +G+ CE K++LCL C HG C D D+ C+C GW G C+ +IDDC PC G C D ++G+ CNC+ +TG C+ + +C+ N Sbjct: 2136 VTIDPCTANGNPCGNGASCQALE-QGRYKCECVPGW--EGIHCEQNINDCSENPCLLGAN-CTDLVNDFQCACPPGFTGKRCE-QKIDLCLSEPCKHGTCVDRLFDHECVCHPGWTGSACDINIDDCENRPCANEGTCVDLVDGYSCNCEPGYTGKNCQ---HTIDDCASN 2298 HSP 2 Score: 96.6709 bits (239), Expect = 2.299e-19 Identity = 67/211 (31.75%), Postives = 99/211 (46.92%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFC--LGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD------------------------------------------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 SN C ATC D F C C PG+VG SCE EIDECL + C +G + RC+DL N F+C+C G C ++ C C++ GICRD D C+C SG +G +C + + CIGDPC G C+D +G C+C +++GI C++++ +C ++ +N C++ Sbjct: 2297 SNPCQHGATCVDQL--DGFSCKCRPGYVG--LSCEAEIDECLSDPCNPVG-TERCLDLDNKFECVCRDGFKGPLCAT-DIDDCEAQPCLNNGICRDRVGGFECGCEPGWSGMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAPERCIGDPCMHGGKCQDFGSGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVD 2501 HSP 3 Score: 82.0333 bits (201), Expect = 7.153e-15 Identity = 56/173 (32.37%), Postives = 77/173 (44.51%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFG-VCLNLKN 5691 + C N C+ F+C C PG+ +G CE+ + C + + CIDL D+ C+C S G+ CE C+ C+HG C+D S C C + + GI C D C C C D G+ C C FTG CE D CK+ S G C++L N Sbjct: 2375 AQPCLNNGICRDRV--GGFECGCEPGW--SGMRCEQQVTTCGAQAPCQNDASCIDLFQDYFCVCPSGTDGKNCETAP-ERCIGDPCMHGGKCQDFGSGLNCSCPADYSGIGCQYEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDIVDCKDNSCPPGATCVDLTN 2542 HSP 4 Score: 75.485 bits (184), Expect = 6.946e-13 Identity = 59/194 (30.41%), Postives = 90/194 (46.39%), Query Frame = 1 Query: 5113 DQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRDDN-----SCLCLSGWEGIDCNKSIDDCI--GDPCNGRGVCEDALNG-FICNCQQNFTGIFCEFDHFSCKNCSEN 5664 + T+ P SKG + + V +C C C + + QCFC GF +G CE+ IDEC C + +C DL ++C C + SG C+ + + C C +C+++ +CLC SG+ G C+ +ID C G+PC C+ G + C C + GI CE + +CSEN Sbjct: 2006 NMRTDSPASKGREQCKPV---VC--GEGACQHGGLCVP--MGHDIQCFCPAGF--SGRRCEQDIDECASQPCY-NGGQCKDLPQGYRCECPAGYSGINCQE-EASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCDVTIDPCTANGNPCGNGASCQALEQGRYKCECVPGWEGIHCEQN---INDCSEN 2185 HSP 5 Score: 69.3218 bits (168), Expect = 4.544e-11 Identity = 47/147 (31.97%), Postives = 69/147 (46.94%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDE-CLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC 5625 C +A+C +L ++ C C G +G +CE E C+ + C+ +C D + C C +D SG C+ + + C + C +G DN SC C G+ G +C + I DC + C C D NGF C C N TG C Sbjct: 2417 CQNDASCI--DLFQDYFCVCPSG--TDGKNCETAPERCIGDPCM-HGGKCQDFGSGLNCSCPADYSGIGCQ-YEYDACEEHVCQNGATCVDNGAGYSCQCPPGFTGRNCEQDIVDCKDNSCPPGATCVDLTNGFYCQCPFNMTGDDC 2557 HSP 6 Score: 61.6178 bits (148), Expect = 1.158e-8 Identity = 37/119 (31.09%), Postives = 55/119 (46.22%), Query Frame = 1 Query: 5344 CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVC--EDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C+ + +D QC C + SGR CE ++ C C +G C+D C C +G+ GI+C + DC D C R +C E C C+ +TG C+ + C+ N C N Sbjct: 2036 CVPMGHDIQCFCPAGFSGRRCE-QDIDECASQPCYNGGQCKDLPQGYRCECPAGYSGINCQEEASDCGNDTCPARAMCKNEPGYKNVTCLCRSGYTGDQCD---VTIDPCTANGNPCGN 2150
BLAST of Protocadherin Fat 4 vs. Ensembl Zebrafish
Match: LO018022.1 (FAT atypical cadherin 4 [Source:NCBI gene;Acc:101882648]) HSP 1 Score: 104.76 bits (260), Expect = 1.352e-21 Identity = 171/743 (23.01%), Postives = 312/743 (41.99%), Query Frame = 1 Query: 157 LEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWK--VEENILVGSLVGQISV--VDEDLDDSFKCSVKSDSPFNVDANFN-LFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVT--DINEAPDKI---YVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--------------NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN-SLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVE--IKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY---FIQLIDVNEAPQGLT--LYPSTVTENIPSGSVIGKFSILDSNL--NSTIEKC--SLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPENLSLSN-NQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKD-FYIEN--NKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNE--PPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSI 2244 L I +D PK ++V I D ND P + ++ V E+ VGS V QI+ +DE + + +PF +D + K LDYET+ + + I +D+ S+ + E +V D+N+ + Y TT++ + +EN++ GT + ++ +D D N+ F +S+ V L+ I++ L + ER S +SV+D + S ++I D N ++ + E+ + +SA D D + + + ++ +S+ +N + +AELN E++ + A KDQ L +Y + + DVN+ T Y ++TE+ P+GS + S DS+L N TI S ++ F + L +T LD E+ +Y L IR TD G + + ++ + + D N+ P + I ENEP G + + A D D +N T+ Y + + F+I + K+ + D E + YQ+ +T D G + + + ++++ +NP + +G K F + EN + T++ D I I S + R L K+ +T +D E+ ++++ + I T + I V+++N+ P +++ ++ EN I +DPD+ N +I YS+ Sbjct: 204 LLIQVEDKGEPKKFGYLQVNVTIQDINDNPPSFDHEQYQTSVFEDAAVGSSVLQIAASDLDEGANAEITYLLDEGTPFQIDPKAGTVVIKEGLDYETKREYSLTIHAVDNGVPSLYTRTEATVKLLDVNDNDPVVKFRYFPTTSK--FASVDENAQVGTVVALLTVSDSDSSTANGNISVSILGGNEQRHFDVHSSPVPN---------------LSLIKVASVL--DRERISSYNLTVSVSDNGKPLARSSFASLVIFVNDINDHPPIFQEAVYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYSLVSGNSLGWFAISENSGLVTSAAELNRETASEIVLNISA-KDQGLQPKISYTKLIVNITDVNDQVPTFTQNTYHVSITEHSPAGSELVVLSATDSDLGPNGTIRFSFDSETPVSDQNKFRLDSTSGRLSTSTELDREEESSYLLYIRATDSGAPPLHSVCKVNITLKDVNDNSPVFYPMQYFANIKENEPSGSSVTTVTASDPDLGRNGTVKYAITAGDSSKFHISSTSGKVTTLVALDREEKTAYQLQVTATDGGGLRSHTPAIVTVTVVDTQDNPLV-----FGQKDYSFVMFENVPVGTIIGTVSATTVDLHTNITYLIASGDQRSLFGIKAG-------QITALGLIDREEQAFYQLRV-IARAGEVTGETLVNITVKDLNDNAPNFMHSVEH-----VSAVENWATGHHIFQAKASDPDEATNGMIVYSL 908 HSP 2 Score: 87.4261 bits (215), Expect = 2.152e-16 Identity = 50/150 (33.33%), Postives = 75/150 (50.00%), Query Frame = 1 Query: 5224 SNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS 5658 SN+ + C C PG+ G + CE +IDEC C + C +LV F C C +G CE VN CL + C +G +C++ CLC SG+ G C+ I+ C +PC G C++ + G+ C+C G CE + + + S Sbjct: 3388 SNQPLQPYACNCRPGYAG--ALCETDIDECQPTPCH-NGGTCHNLVGGFSCTCPDGFTGMACE-RDVNECLSNPCQNGALCQNYPGGFNCLCKSGFAGKACDSVINYCECNPCFNGGSCQNRVEGYYCHCPFGVFGKHCELNSYGFEELS 3533 HSP 3 Score: 69.707 bits (169), Expect = 5.750e-11 Identity = 83/320 (25.94%), Postives = 144/320 (45.00%), Query Frame = 1 Query: 1348 LELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIP--ENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTV-----FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVF-HIMENNELEMTFATITVFEPD---FDDKINCQIISDN-SRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN---FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILN 2250 L L LD E TP Y L I+V D G+ ++ + I D N+ P + Q E+ +G + I A D D+ N+ + Y LD F I+ +GTV D+E + Y +TI DNG P L +++L+ N+N + ++K +Y T F + EN ++ A +TV + D + I+ I+ N R S + N+ + + LD E+ + + + + ++D ++ + IFV ++N+ P R ++I+E+I I TD D QN ++YS+++ Sbjct: 186 LHLVSTGGLDRETTPFYQLLIQVEDKGEPKKFGYLQVNVTIQDINDNPPSFDHEQYQTSVFEDAAVGSSVLQIAASDLDEGANAEITYLLDEGTP-FQIDPK---AGTVVIKEGLDYETKREYSLTIHAVDNGVPSLYTRTEATVKLLDVNDN-DPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSSTANGNISVSILGGNEQRHFDVHSSPVPNLSL--IKVASVLDRERISSYNLTVSVSDNGKPLARSSFASLVIFVNDINDHPPIFQEAVYR---VDISEDIPKGSYIKGVSATDGDSGQNANLRYSLVS 495 HSP 4 Score: 63.1586 bits (152), Expect = 4.364e-9 Identity = 27/71 (38.03%), Postives = 36/71 (50.70%), Query Frame = 1 Query: 5473 SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 +C C G+ G C ID+C PC+ G C + + GF C C FTG+ CE D C N +N +C N Sbjct: 3396 ACNCRPGYAGALCETDIDECQPTPCHNGGTCHNLVGGFSCTCPDGFTGMACERDVNECLSNPCQNGALCQN 3466 HSP 5 Score: 62.3882 bits (150), Expect = 9.056e-9 Identity = 130/577 (22.53%), Postives = 236/577 (40.90%), Query Frame = 1 Query: 109 SISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND-PPTNIQLS-NWKVEENILVGSLVGQISVVDEDLDDSFK-----CSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVT--DINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNS-TDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEI-----VKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSA--IDEDINELYSFQILILHTDSVEIKH----KNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPST----VTENIPSGSVIGKFSILDSNLNSTIE-KCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEK---DFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDP 1725 S++ PL E T++ LE++A DL VP+ + + +++ D ND P QLS + E+ V S ++ D+D + + S + F + + L+ KA LD E Q R+ +++ D S+ +S+ DIN+ ++ N+TN + E + G +G ++ D D F NS S + Q T LT +Q + ++ F +V + + V++ I ++++NP K + E + L +SA +DE+ N L + I T+ E K N + +L+YE++ + A + + T + + +++ + ST V EN+ G ++ + DS+ S + S+ + F IS + +LDYE Y L + D G+ + + +I+ + D N+ P + + IPEN PI + I A D D N L Y++ + F I++ +SG ++ D E +++TI D P Sbjct: 926 SLTGPL--EVTTSSYQLEVVASDLGVPQRTSSLFLTISVYDVNDNAPVFDQLSYEVTILESEPVNSRFFRVEATDKDSGVNGEIVYDIISGNTRDVFGIFPDGQLYIKADLDREVQDRYSLLVVAKDRAVESLSASVNVSILLDDIND--NRPLFNSTN--YVFHFEEEQERGALVGRVFAEDKD------FGPNSEVRYSFETPQSNFELNAITGVLTST-LQLDRESLMRQRGAAVFSFTVLSSDQGLPKPLKDQAKVQVYIQDINDNPP--KFTKDIYQASIAESAQNMTQLLRVSASDVDENKNGLVHYDI----TEGNEEKQFSIDSNSGQVTLVGKLDYETTPSYSLKIIAEDSGSVPLSSTCVLSISVLDDNDNSPSFPKSTLSVDVLENMRIGELVASVTATDSDSGSNADITYSISATNNHGTFSISPNTGSIFLVKKLDYETQSLYKLNVTAKDSGRPSRSSSIPVIIHVRDFNDNPPVFTPGDIFKSIPENLPISTSVMSITAHDTDADINGLLEYSIALQTPRGGHFRIDS---VSGVIYTNKDIDREFSNLFELTIKATDQAVP 1480 HSP 6 Score: 59.6918 bits (143), Expect = 6.185e-8 Identity = 114/490 (23.27%), Postives = 213/490 (43.47%), Query Frame = 1 Query: 772 ERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSL-GELSAIDEDINE----LYSFQ----------ILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLT--LYPSTVTENIPSGSVIGKFSI--LDSNLNSTIEKCSLQLITFNE--IFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIP--ENEPIGLLIAIINAQDND--KNSTLVYTLDV--NEKDFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFH-IMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDM------KNFTAIMKIFIFVENVNE 2109 E Q + DR SLS V + IL +D+ + L +ST+ EE +L G + A D+D YSF+ I + T ++++ ++ + + +A ++ + + KDQ + +IQ D+N+ P T +Y +++ E+ + + + + S +D N N + + NE F I ++ +LDYE TP+Y+L I D G + + + + + D N+ + S + EN IG L+A + A D+D N+ + Y++ N F I N +G++F D+E + Y++ +T D+G P + S I + + N+NP + ++F I EN + + +IT + D D IN + + + ++ F+ D + N+ +D E +N FE+ I+ D + F A+ + I+V + N+ Sbjct: 1037 EVQDRYSLLVVAKDRAVESLSASVNVSIL-LDDINDNRPLFNSTNYVFHFEEEQERGALVGRVFAEDKDFGPNSEVRYSFETPQSNFELNAITGVLTSTLQLDRESLMRQRGAAVFSFTVLSSDQGLPKPLKDQAKV---QVYIQ--DINDNPPKFTKDIYQASIAESAQNMTQLLRVSASDVDENKNGLVH---YDITEGNEEKQFSIDSNSGQVTLVGKLDYETTPSYSLKIIAEDSGSVPLSSTCVLSISVLDDNDNSPSFPKSTLSVDVLENMRIGELVASVTATDSDSGSNADITYSISATNNHGTFSISPN---TGSIFLVKKLDYETQSLYKLNVTAKDSGRPSRSSSIPVIIHVRDFNDNPPVFTPG------DIFKSIPENLPISTSVMSITAHDTDAD--INGLL-----EYSIALQTPRGGHFRIDSVSGVIYTNKDIDREFSNLFELTIKATDQAVPAEFRRF-ALKNVTIWVTDQND 1500 HSP 7 Score: 56.9954 bits (136), Expect = 3.229e-7 Identity = 135/687 (19.65%), Postives = 263/687 (38.28%), Query Frame = 1 Query: 106 YSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPT--NIQLSNWKVEENILVGSLVGQISVVDED------LDDSFKCSVKS-DSPFNVDANFNLF-TKAPLDYETQARFEVIIECLDHENSSVINKHEISVT---DINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENP-TDLKLNDST--------SNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIK--------HKNELWI--KESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLS-LSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDF----YIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPD--FDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIN 2049 ++++ L+FE++ I + + D S ++ +LD ND P N + + E++ G+ V +S D D L +S S+ D F+++ + L T + LD ET+A +++++ D + ++ DIN+ P + + + + ++ +G+ + + D D + + + T + + + + IR SE+ F + V D N ++ + + V +KL D +N ++ + S+ G LS N +F I L + + I+ K LWI ++ Y + V D +F + F I N +PQ + + + ++ P+G + +++I+D N ++ F I++ E++ LD EK Y+L ++ TD G T ++++ + D N+ S + + +PEN P+G + + D D + + + + + + + E+ Y ++ D+G VS I + + N+N K Y E E+ ++ +PD F+ KI I S F + S IF I Q L Y QN+ NI +N Sbjct: 1859 FNVTRALDFETQPFFI---LTVRAADGGGRSSSVRVYFNLLDVNDHPPLFNSSVYTTSILESLSAGASVLTVSAADRDHGNSSTLLNSVHYSLSGGDGQFSINPSTGLIITSSLLDRETRASYQLLVVASDGGQPTPLSSSATVSVVVADINDNPPRFH----HHPYVTHIPASTSTGSLVFAVTVTDEDSGSNSQLHYSLTGRNSEKFK-----------IDPIRGAITASEKLTGSSEVTFTVHVKDGGTNPKTDSTTVTVRFVTGGDFPHIKLKDKAFTFPENQPTNTIVTKVTGSSPRAGPLSYYIASGNLDNAFHIDQL-SGELSIRKPLDYENIEKYVLWIEARDQGFPPYSAYEKVEIAVLDVNDNHPVFEQEPFHAEILENLSPQRVLVVSALDQDSGPNGQL--EYAIIDGNKENS--------------FNINRATGEIRTTRPLDREKVAQYSLRVKATDRGMPPKSTAVKVLISVLDVNDNAPRFSKIFSATVPENAPVGFTVTRVTTTDEDAGANAISRYSITDASLPFIIHPSTGDITISRPLNREDTDHYIAKVSAHDSG---WTVSTDVTIFVTDINDNAPRFSKPSY-----YLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFIRSQTEYFRINSSS--GEIF-----IKQQLRY-QNSSGHNNINVN 2494 HSP 8 Score: 56.225 bits (134), Expect = 5.618e-7 Identity = 156/776 (20.10%), Postives = 302/776 (38.92%), Query Frame = 1 Query: 1516 QIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFD----DKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQT-------------LDYEQNNYFEINIEINDM---KNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND-PPTVAGLNFTMIPSFVEKD------FIIGKVNVFDEDNLSTYNQIECSIIKP--LKWFSILNIS-QNLEIVTTATRFIDEKF--IDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFN-WTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDP--LDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKN---LTMFEKSPPNIHIATFYATDPDYNQ----IHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKE----SANINTVLAXXXXXXXXXXXXHQ-CHGSNSYFGISNSSIYIAK--RLDYETFTKMETIVVCFDQSGL--NVSSVFQIDIEDVNEPP 3678 ++ E +P+G + I + Y K F I + + +V D E PG I + V + + I +L+ N+N + + + + V E+ T + D D +IIS N Q+K F+ D+T+N + LD E ++++ I++ D K F +++ + ++++N+ P + ++ E+ S+ +D D+ + + L L+ F+ + +KE DYE+ ++ + I A+D+G L E + + D ND P V F F D ++ + V D D+ + I SI+ + F + + NL ++ A+ E+ ++ + +NG +S+ S + + DIN+ P F + VD ++E+ S + + TD S Q + ++ N++ +NS ++T L+ ET + +++ + D+ I+ I+++ + ++ +F +N +++ E SP + ATD D SFD + + + F + + L T S+Y+ Y I D G P L + I + +VND + IKE +++ TV A + + G +S F IS++S + LD E T + V D GL + ++ + + D + P Sbjct: 36 EVLEEQPVGTYVGTIETK-----PAFTYRFSEQHKLFSINATTGVIYTSSVIDREVLPGNIINVVVLSS---QPTYPTEVRIVVLDINDNAPV-----FPDASIVVSFKEDASSGRQVILDTATDADIGSNGVDHTTYRIISGND----QRK------FRLDITVNPSGEGAFLHLVSTGGLDRETTPFYQLLIQVEDKGEPKKF-GYLQVNVTIQDINDNPPSF---DHEQYQTSVFEDAAVGSSVLQIAASDLDEGANAEITYL--LDEGTPFQIDPKAGTVVIKEG--LDYETK--REYSLTIHAVDNGVPSLYTRTEATVKLLDVNDNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSSTANGNISVSILGGNEQRHFDVHSSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGKPLARSSFASLVIFVNDINDHPPIFQEAVYRVD-ISEDIPKGSYIKGVSATD--GDSGQNANLRYSLVSGNSLGWFAISENSGLVTSAAELNRETASEIVLNISAKDQGLQPKISYTKLIVNITDVNDQVPTFTQNTYHVSITEHSPAGSELVVLSATDSDLGPNGTIRFSFDSETPVSDQNKFR---LDSTSGRLSTSTELDREEESSYLLY----IRATDSGAPPLHSVCKVNITLKDVNDNSPVFYPMQYFANIKENEPSGSSVTTVTASDPDLGRNGTVKYAITAGDSSKFHISSTSGKVTTLVALDREEKTAYQLQVTATDGGGLRSHTPAIVTVTVVDTQDNP 768 HSP 9 Score: 54.6842 bits (130), Expect = 1.865e-6 Identity = 60/282 (21.28%), Postives = 116/282 (41.13%), Query Frame = 1 Query: 1105 VVGAYKDQILIFNKTYFIQLIDVNEAPQ-GLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNE--IFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDND---KNSTLVYTL---DVNEKDFYIE-NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVF-HIMENNELEMTFATITVFEPDFDDKINCQI 1917 + GA D++L+ I ++D N+ P LY V E + G ++ S DS+ + + + + +E F I+ ++ + LD E P YNL I D G +I+ + D N+ L + ++ EN+ G + ++++D D Y+L F I +L + D E + +++ + D+G P+++ + T I++ + N+NP E++ H N + + +PD D C + Sbjct: 2930 IRGADIDEVLVN-----ITVLDANDPPVFTQELYDVQVNEGLSPGGLVTFVSAEDSDSVPSWSRFTYAIAANHERNTFTINPQTGQVSVASELDRETVPVYNLTILAVDSGSPAATGSAILIVTLEDINDNGPTLVTTYGEVMENQRAGTPVMTLSSRDPDLAPNQGPFTYSLVSTGAASSYFTISPTGELTTSREVDREQISDFYLSVLIKDSGIPQMSSTGTVHIKVNDQNDNP------SESRSVEIYVHYFGNMFPGGSLGVVKPQDPDIQDTFQCSL 3200 HSP 10 Score: 52.7582 bits (125), Expect = 6.137e-6 Identity = 211/952 (22.16%), Postives = 372/952 (39.08%), Query Frame = 1 Query: 763 FNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNEL-----WIKESAELNYE--SSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYP----STVTENIPSGSVIGKFSILDSNL--NSTIEKCSLQLITFNEI--FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ--IPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKD--FYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFAT-ITVFEP---DFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYE-QNNYFEINIEINDM----KNFTAIMKIFIFVENVNEPPTKLAIDG-SREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFE-FSNGGSKLYLKESQFFDYESNIGKDIKVLI----RAIDSGGLSIDLEVPISIQDAND-PPTVAGLNFTM-IPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFI---------DIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIV--LVSNNIKIQINED---NSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNE-APSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKI-VNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINT 3453 N E SE+ IS D+ K+I+ D N +T + + E + + L LSA D D+ + + V ++K L + S EL+ E SSY+ Y L I L DVN+ YP + + EN PSGS + + D +L N T++ IT + F IS ++ LD E+ AY L + TD G T + + + D + P + + EN P+G +I ++A D ++ + Y + ++ F I+ ++ + + D E + YQ+ + + ++N I +KD N H +E+ +AT +F+ D D+ N I+ L Q + +I + I+ T E + +++ + +D+ + + + I ++ N N P D S E+ I +E + D N I Y I++ N + F F +G +LY+K D + + +L+ RA++S LS + V I + D ND P N+ E+ ++G+V D+D +++ S P F + I+ V T+T +D + + + + G K + I+DIN+ P F+ + + E++ N++ QLL + S + +K+ ++ + N + Q + D L LDYET ++ + D S + + L + +LD N+ +PS KS ++ + E +A+ ATD D + DI I NH I N + V LD + + + + +D G+PS S I + + ND P +I E+ I+T Sbjct: 517 LNRETASEIVLNISAKDQGLQPKISYTKLIVNITDVNDQVPTFTQNTYHVSITEHSPAGSELVVLSATDSDLGPNGTIRFSFDSETPVSDQNKFRLDSTSGRLSTSTELDREEESSYLLYIRATDSGAPPLHSVCKVNITLKDVND--NSPVFYPMQYFANIKENEPSGSSVTTVTASDPDLGRNGTVKYA----ITAGDSSKFHISSTSGKVTTLVALDREEKTAYQLQVTATDGGGLRSHTPAIVTVTVVDTQDNPLVFGQKDYSFVMFENVPVGTIIGTVSATTVDLHTNITYLIASGDQRSLFGIKAGQITALGLIDREEQAFYQLRVIA--------RAGEVTGETLVN------ITVKDLNDNAPNFMHSVEHVSAVENWATGHHIFQAKASDPDEATNGMIVYS----LKQNPKGLFHIHEKHGLISLTGPLEVTTSSYQLEVVASDLGVPQRTSSLFLTISVYDVNDNAP----VFDQLSYEVTILESEPVNSRFFRVEATDKDSGVNGEIVYDIISG-NTRDVFGIFPDG--QLYIKA----DLDREVQDRYSLLVVAKDRAVES--LSASVNVSILLDDINDNRPLFNSTNYVFHFEEEQERGALVGRVFAEDKD-FGPNSEVRYSFETPQSNFELNAITG----VLTSTLQLDRESLMRQRGAAVFSFTVLSSDQGLPKPLKDQAKVQVYIQDINDNPPKFTKDIYQASIAESAQNMT--QLLRV---SASDVDENKNGLVHYDITEGNEEKQFSIDSNSGQVTLVGKLDYETTPSYSLKIIAEDSGSVPLSSTCVLSISVLDDNDNSPSFPKS-TLSVDVLENMRIGELVASVTATDSDSGS--NADITYSI--SATNNHGTFSISPNTGSIFLVKKLDYETQ---SLYKLNVTAKDSGRPSRSSSIPVIIHVRDFNDNPPVFTPGDIFKSIPENLPIST 1413
BLAST of Protocadherin Fat 4 vs. Ensembl Zebrafish
Match: LO018022.1 (FAT atypical cadherin 4 [Source:NCBI gene;Acc:101882648]) HSP 1 Score: 104.76 bits (260), Expect = 1.398e-21 Identity = 171/743 (23.01%), Postives = 312/743 (41.99%), Query Frame = 1 Query: 157 LEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWK--VEENILVGSLVGQISV--VDEDLDDSFKCSVKSDSPFNVDANFN-LFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVT--DINEAPDKI---YVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--------------NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN-SLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVE--IKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY---FIQLIDVNEAPQGLT--LYPSTVTENIPSGSVIGKFSILDSNL--NSTIEKC--SLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPENLSLSN-NQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKD-FYIEN--NKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNE--PPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSI 2244 L I +D PK ++V I D ND P + ++ V E+ VGS V QI+ +DE + + +PF +D + K LDYET+ + + I +D+ S+ + E +V D+N+ + Y TT++ + +EN++ GT + ++ +D D N+ F +S+ V L+ I++ L + ER S +SV+D + S ++I D N ++ + E+ + +SA D D + + + ++ +S+ +N + +AELN E++ + A KDQ L +Y + + DVN+ T Y ++TE+ P+GS + S DS+L N TI S ++ F + L +T LD E+ +Y L IR TD G + + ++ + + D N+ P + I ENEP G + + A D D +N T+ Y + + F+I + K+ + D E + YQ+ +T D G + + + ++++ +NP + +G K F + EN + T++ D I I S + R L K+ +T +D E+ ++++ + I T + I V+++N+ P +++ ++ EN I +DPD+ N +I YS+ Sbjct: 212 LLIQVEDKGEPKKFGYLQVNVTIQDINDNPPSFDHEQYQTSVFEDAAVGSSVLQIAASDLDEGANAEITYLLDEGTPFQIDPKAGTVVIKEGLDYETKREYSLTIHAVDNGVPSLYTRTEATVKLLDVNDNDPVVKFRYFPTTSK--FASVDENAQVGTVVALLTVSDSDSSTANGNISVSILGGNEQRHFDVHSSPVPN---------------LSLIKVASVL--DRERISSYNLTVSVSDNGKPLARSSFASLVIFVNDINDHPPIFQEAVYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYSLVSGNSLGWFAISENSGLVTSAAELNRETASEIVLNISA-KDQGLQPKISYTKLIVNITDVNDQVPTFTQNTYHVSITEHSPAGSELVVLSATDSDLGPNGTIRFSFDSETPVSDQNKFRLDSTSGRLSTSTELDREEESSYLLYIRATDSGAPPLHSVCKVNITLKDVNDNSPVFYPMQYFANIKENEPSGSSVTTVTASDPDLGRNGTVKYAITAGDSSKFHISSTSGKVTTLVALDREEKTAYQLQVTATDGGGLRSHTPAIVTVTVVDTQDNPLV-----FGQKDYSFVMFENVPVGTIIGTVSATTVDLHTNITYLIASGDQRSLFGIKAG-------QITALGLIDREEQAFYQLRV-IARAGEVTGETLVNITVKDLNDNAPNFMHSVEH-----VSAVENWATGHHIFQAKASDPDEATNGMIVYSL 916 HSP 2 Score: 87.0409 bits (214), Expect = 2.611e-16 Identity = 50/150 (33.33%), Postives = 75/150 (50.00%), Query Frame = 1 Query: 5224 SNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS 5658 SN+ + C C PG+ G + CE +IDEC C + C +LV F C C +G CE VN CL + C +G +C++ CLC SG+ G C+ I+ C +PC G C++ + G+ C+C G CE + + + S Sbjct: 3394 SNQPLQPYACNCRPGYAG--ALCETDIDECQPTPCH-NGGTCHNLVGGFSCTCPDGFTGMACE-RDVNECLSNPCQNGALCQNYPGGFNCLCKSGFAGKACDSVINYCECNPCFNGGSCQNRVEGYYCHCPFGVFGKHCELNSYGFEELS 3539 HSP 3 Score: 69.707 bits (169), Expect = 5.654e-11 Identity = 83/320 (25.94%), Postives = 144/320 (45.00%), Query Frame = 1 Query: 1348 LELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIP--ENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTV-----FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVF-HIMENNELEMTFATITVFEPD---FDDKINCQIISDN-SRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN---FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILN 2250 L L LD E TP Y L I+V D G+ ++ + I D N+ P + Q E+ +G + I A D D+ N+ + Y LD F I+ +GTV D+E + Y +TI DNG P L +++L+ N+N + ++K +Y T F + EN ++ A +TV + D + I+ I+ N R S + N+ + + LD E+ + + + + ++D ++ + IFV ++N+ P R ++I+E+I I TD D QN ++YS+++ Sbjct: 194 LHLVSTGGLDRETTPFYQLLIQVEDKGEPKKFGYLQVNVTIQDINDNPPSFDHEQYQTSVFEDAAVGSSVLQIAASDLDEGANAEITYLLDEGTP-FQIDPK---AGTVVIKEGLDYETKREYSLTIHAVDNGVPSLYTRTEATVKLLDVNDN-DPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSSTANGNISVSILGGNEQRHFDVHSSPVPNLSL--IKVASVLDRERISSYNLTVSVSDNGKPLARSSFASLVIFVNDINDHPPIFQEAVYR---VDISEDIPKGSYIKGVSATDGDSGQNANLRYSLVS 503 HSP 4 Score: 63.1586 bits (152), Expect = 4.787e-9 Identity = 27/71 (38.03%), Postives = 36/71 (50.70%), Query Frame = 1 Query: 5473 SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 +C C G+ G C ID+C PC+ G C + + GF C C FTG+ CE D C N +N +C N Sbjct: 3402 ACNCRPGYAGALCETDIDECQPTPCHNGGTCHNLVGGFSCTCPDGFTGMACERDVNECLSNPCQNGALCQN 3472 HSP 5 Score: 62.3882 bits (150), Expect = 8.831e-9 Identity = 130/577 (22.53%), Postives = 236/577 (40.90%), Query Frame = 1 Query: 109 SISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND-PPTNIQLS-NWKVEENILVGSLVGQISVVDEDLDDSFK-----CSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVT--DINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNS-TDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEI-----VKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSA--IDEDINELYSFQILILHTDSVEIKH----KNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPST----VTENIPSGSVIGKFSILDSNLNSTIE-KCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEK---DFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDP 1725 S++ PL E T++ LE++A DL VP+ + + +++ D ND P QLS + E+ V S ++ D+D + + S + F + + L+ KA LD E Q R+ +++ D S+ +S+ DIN+ ++ N+TN + E + G +G ++ D D F NS S + Q T LT +Q + ++ F +V + + V++ I ++++NP K + E + L +SA +DE+ N L + I T+ E K N + +L+YE++ + A + + T + + +++ + ST V EN+ G ++ + DS+ S + S+ + F IS + +LDYE Y L + D G+ + + +I+ + D N+ P + + IPEN PI + I A D D N L Y++ + F I++ +SG ++ D E +++TI D P Sbjct: 934 SLTGPL--EVTTSSYQLEVVASDLGVPQRTSSLFLTISVYDVNDNAPVFDQLSYEVTILESEPVNSRFFRVEATDKDSGVNGEIVYDIISGNTRDVFGIFPDGQLYIKADLDREVQDRYSLLVVAKDRAVESLSASVNVSILLDDIND--NRPLFNSTN--YVFHFEEEQERGALVGRVFAEDKD------FGPNSEVRYSFETPQSNFELNAITGVLTST-LQLDRESLMRQRGAAVFSFTVLSSDQGLPKPLKDQAKVQVYIQDINDNPP--KFTKDIYQASIAESAQNMTQLLRVSASDVDENKNGLVHYDI----TEGNEEKQFSIDSNSGQVTLVGKLDYETTPSYSLKIIAEDSGSVPLSSTCVLSISVLDDNDNSPSFPKSTLSVDVLENMRIGELVASVTATDSDSGSNADITYSISATNNHGTFSISPNTGSIFLVKKLDYETQSLYKLNVTAKDSGRPSRSSSIPVIIHVRDFNDNPPVFTPGDIFKSIPENLPISTSVMSITAHDTDADINGLLEYSIALQTPRGGHFRIDS---VSGVIYTNKDIDREFSNLFELTIKATDQAVP 1488 HSP 6 Score: 59.6918 bits (143), Expect = 6.134e-8 Identity = 114/491 (23.22%), Postives = 211/491 (42.97%), Query Frame = 1 Query: 772 ERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSL-GELSAIDEDINE----LYSFQ----------ILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLT--LYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDN-----TRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIP--ENEPIGLLIAIINAQDND--KNSTLVYTLDV--NEKDFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFH-IMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDM------KNFTAIMKIFIFVENVNE 2109 E Q + DR SLS V + IL +D+ + L +ST+ EE +L G + A D+D YSF+ I + T ++++ ++ + + +A ++ + + KDQ + +IQ D+N+ P T +Y +++ E+ + + + + S D + N K L E QF ++ +LDYE TP+Y+L I D G + + + + + D N+ + S + EN IG L+A + A D+D N+ + Y++ N F I N +G++F D+E + Y++ +T D+G P + S I + + N+NP + ++F I EN + + +IT + D D IN + + + ++ F+ D + N+ +D E +N FE+ I+ D + F A+ + I+V + N+ Sbjct: 1045 EVQDRYSLLVVAKDRAVESLSASVNVSIL-LDDINDNRPLFNSTNYVFHFEEEQERGALVGRVFAEDKDFGPNSEVRYSFETPQSNFELNAITGVLTSTLQLDRESLMRQRGAAVFSFTVLSSDQGLPKPLKDQAKV---QVYIQ--DINDNPPKFTKDIYQASIAESAQNMTQLLRVSASDVDEN----KNGLVHYDITEGNEEKQFSIDSNSGQVTLVGKLDYETTPSYSLKIIAEDSGSVPLSSTCVLSISVLDDNDNSPSFPKSTLSVDVLENMRIGELVASVTATDSDSGSNADITYSISATNNHGTFSISPN---TGSIFLVKKLDYETQSLYKLNVTAKDSGRPSRSSSIPVIIHVRDFNDNPPVFTPG------DIFKSIPENLPISTSVMSITAHDTDAD--INGLL-----EYSIALQTPRGGHFRIDSVSGVIYTNKDIDREFSNLFELTIKATDQAVPAEFRRF-ALKNVTIWVTDQND 1508 HSP 7 Score: 57.7658 bits (138), Expect = 1.904e-7 Identity = 135/685 (19.71%), Postives = 262/685 (38.25%), Query Frame = 1 Query: 106 YSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPT--NIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKC--SVK---SDSPFNVDANFNLF-TKAPLDYETQARFEVIIECLDHENSSVINKHEISVT---DINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENP-TDLKLNDST--------SNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIK--------HKNELWI--KESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLS-LSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDF----YIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPD--FDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIN 2049 ++++ L+FE++ I + + D S ++ +LD ND P N + + E++ G+ V +S D D +S SV D F+++ + L T + LD ET+A +++++ D + ++ DIN+ P + + + + ++ +G+ + + D D + + + T + + + + IR SE+ F + V D N ++ + + V +KL D +N ++ + S+ G LS N +F I L + + I+ K LWI ++ Y + V D +F + F I N +PQ + + + ++ P+G + +++I+D N ++ F I++ E++ LD EK Y+L ++ TD G T ++++ + D N+ S + + +PEN P+G + + D D + + + + + + + E+ Y ++ D+G VS I + + N+N K Y E E+ ++ +PD F+ KI I S F + S IF I Q L Y QN+ NI +N Sbjct: 1867 FNVTRALDFETQPFFI---LTVRAADGGGRSSSVRVYFNLLDVNDHPPLFNSSVYTTSILESLSAGASVLTVSAADRDHGNSSTLLNSVHLSGGDGQFSINPSTGLIITSSLLDRETRASYQLLVVASDGGQPTPLSSSATVSVVVADINDNPPRFH----HHPYVTHIPASTSTGSLVFAVTVTDEDSGSNSQLHYSLTGRNSEKFK-----------IDPIRGAITASEKLTGSSEVTFTVHVKDGGTNPKTDSTTVTVRFVTGGDFPHIKLKDKAFTFPENQPTNTIVTKVTGSSPRAGPLSYYIASGNLDNAFHIDQL-SGELSIRKPLDYENIEKYVLWIEARDQGFPPYSAYEKVEIAVLDVNDNHPVFEQEPFHAEILENLSPQRVLVVSALDQDSGPNGQL--EYAIIDGNKENS--------------FNINRATGEIRTTRPLDREKVAQYSLRVKATDRGMPPKSTAVKVLISVLDVNDNAPRFSKIFSATVPENAPVGFTVTRVTTTDEDAGANAISRYSITDASLPFIIHPSTGDITISRPLNREDTDHYIAKVSAHDSG---WTVSTDVTIFVTDINDNAPRFSKPSY-----YLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFIRSQTEYFRINSSS--GEIF-----IKQQLRY-QNSSGHNNINVN 2500 HSP 8 Score: 56.225 bits (134), Expect = 5.958e-7 Identity = 156/776 (20.10%), Postives = 302/776 (38.92%), Query Frame = 1 Query: 1516 QIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFD----DKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQT-------------LDYEQNNYFEINIEINDM---KNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND-PPTVAGLNFTMIPSFVEKD------FIIGKVNVFDEDNLSTYNQIECSIIKP--LKWFSILNIS-QNLEIVTTATRFIDEKF--IDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFN-WTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDP--LDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKN---LTMFEKSPPNIHIATFYATDPDYNQ----IHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKE----SANINTVLAXXXXXXXXXXXXHQ-CHGSNSYFGISNSSIYIAK--RLDYETFTKMETIVVCFDQSGL--NVSSVFQIDIEDVNEPP 3678 ++ E +P+G + I + Y K F I + + +V D E PG I + V + + I +L+ N+N + + + + V E+ T + D D +IIS N Q+K F+ D+T+N + LD E ++++ I++ D K F +++ + ++++N+ P + ++ E+ S+ +D D+ + + L L+ F+ + +KE DYE+ ++ + I A+D+G L E + + D ND P V F F D ++ + V D D+ + I SI+ + F + + NL ++ A+ E+ ++ + +NG +S+ S + + DIN+ P F + VD ++E+ S + + TD S Q + ++ N++ +NS ++T L+ ET + +++ + D+ I+ I+++ + ++ +F +N +++ E SP + ATD D SFD + + + F + + L T S+Y+ Y I D G P L + I + +VND + IKE +++ TV A + + G +S F IS++S + LD E T + V D GL + ++ + + D + P Sbjct: 44 EVLEEQPVGTYVGTIETK-----PAFTYRFSEQHKLFSINATTGVIYTSSVIDREVLPGNIINVVVLSS---QPTYPTEVRIVVLDINDNAPV-----FPDASIVVSFKEDASSGRQVILDTATDADIGSNGVDHTTYRIISGND----QRK------FRLDITVNPSGEGAFLHLVSTGGLDRETTPFYQLLIQVEDKGEPKKF-GYLQVNVTIQDINDNPPSF---DHEQYQTSVFEDAAVGSSVLQIAASDLDEGANAEITYL--LDEGTPFQIDPKAGTVVIKEG--LDYETK--REYSLTIHAVDNGVPSLYTRTEATVKLLDVNDNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSSTANGNISVSILGGNEQRHFDVHSSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGKPLARSSFASLVIFVNDINDHPPIFQEAVYRVD-ISEDIPKGSYIKGVSATD--GDSGQNANLRYSLVSGNSLGWFAISENSGLVTSAAELNRETASEIVLNISAKDQGLQPKISYTKLIVNITDVNDQVPTFTQNTYHVSITEHSPAGSELVVLSATDSDLGPNGTIRFSFDSETPVSDQNKFR---LDSTSGRLSTSTELDREEESSYLLY----IRATDSGAPPLHSVCKVNITLKDVNDNSPVFYPMQYFANIKENEPSGSSVTTVTASDPDLGRNGTVKYAITAGDSSKFHISSTSGKVTTLVALDREEKTAYQLQVTATDGGGLRSHTPAIVTVTVVDTQDNP 776 HSP 9 Score: 54.6842 bits (130), Expect = 1.994e-6 Identity = 60/282 (21.28%), Postives = 116/282 (41.13%), Query Frame = 1 Query: 1105 VVGAYKDQILIFNKTYFIQLIDVNEAPQ-GLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNE--IFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDND---KNSTLVYTL---DVNEKDFYIE-NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVF-HIMENNELEMTFATITVFEPDFDDKINCQI 1917 + GA D++L+ I ++D N+ P LY V E + G ++ S DS+ + + + + +E F I+ ++ + LD E P YNL I D G +I+ + D N+ L + ++ EN+ G + ++++D D Y+L F I +L + D E + +++ + D+G P+++ + T I++ + N+NP E++ H N + + +PD D C + Sbjct: 2936 IRGADIDEVLVN-----ITVLDANDPPVFTQELYDVQVNEGLSPGGLVTFVSAEDSDSVPSWSRFTYAIAANHERNTFTINPQTGQVSVASELDRETVPVYNLTILAVDSGSPAATGSAILIVTLEDINDNGPTLVTTYGEVMENQRAGTPVMTLSSRDPDLAPNQGPFTYSLVSTGAASSYFTISPTGELTTSREVDREQISDFYLSVLIKDSGIPQMSSTGTVHIKVNDQNDNP------SESRSVEIYVHYFGNMFPGGSLGVVKPQDPDIQDTFQCSL 3206 HSP 10 Score: 53.1434 bits (126), Expect = 5.985e-6 Identity = 211/952 (22.16%), Postives = 372/952 (39.08%), Query Frame = 1 Query: 763 FNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNEL-----WIKESAELNYE--SSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYP----STVTENIPSGSVIGKFSILDSNL--NSTIEKCSLQLITFNEI--FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ--IPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKD--FYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFAT-ITVFEP---DFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYE-QNNYFEINIEINDM----KNFTAIMKIFIFVENVNEPPTKLAIDG-SREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFE-FSNGGSKLYLKESQFFDYESNIGKDIKVLI----RAIDSGGLSIDLEVPISIQDAND-PPTVAGLNFTM-IPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFI---------DIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIV--LVSNNIKIQINED---NSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNE-APSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKI-VNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINT 3453 N E SE+ IS D+ K+I+ D N +T + + E + + L LSA D D+ + + V ++K L + S EL+ E SSY+ Y L I L DVN+ YP + + EN PSGS + + D +L N T++ IT + F IS ++ LD E+ AY L + TD G T + + + D + P + + EN P+G +I ++A D ++ + Y + ++ F I+ ++ + + D E + YQ+ + + ++N I +KD N H +E+ +AT +F+ D D+ N I+ L Q + +I + I+ T E + +++ + +D+ + + + I ++ N N P D S E+ I +E + D N I Y I++ N + F F +G +LY+K D + + +L+ RA++S LS + V I + D ND P N+ E+ ++G+V D+D +++ S P F + I+ V T+T +D + + + + G K + I+DIN+ P F+ + + E++ N++ QLL + S + +K+ ++ + N + Q + D L LDYET ++ + D S + + L + +LD N+ +PS KS ++ + E +A+ ATD D + DI I NH I N + V LD + + + + +D G+PS S I + + ND P +I E+ I+T Sbjct: 525 LNRETASEIVLNISAKDQGLQPKISYTKLIVNITDVNDQVPTFTQNTYHVSITEHSPAGSELVVLSATDSDLGPNGTIRFSFDSETPVSDQNKFRLDSTSGRLSTSTELDREEESSYLLYIRATDSGAPPLHSVCKVNITLKDVND--NSPVFYPMQYFANIKENEPSGSSVTTVTASDPDLGRNGTVKYA----ITAGDSSKFHISSTSGKVTTLVALDREEKTAYQLQVTATDGGGLRSHTPAIVTVTVVDTQDNPLVFGQKDYSFVMFENVPVGTIIGTVSATTVDLHTNITYLIASGDQRSLFGIKAGQITALGLIDREEQAFYQLRVIA--------RAGEVTGETLVN------ITVKDLNDNAPNFMHSVEHVSAVENWATGHHIFQAKASDPDEATNGMIVYS----LKQNPKGLFHIHEKHGLISLTGPLEVTTSSYQLEVVASDLGVPQRTSSLFLTISVYDVNDNAP----VFDQLSYEVTILESEPVNSRFFRVEATDKDSGVNGEIVYDIISG-NTRDVFGIFPDG--QLYIKA----DLDREVQDRYSLLVVAKDRAVES--LSASVNVSILLDDINDNRPLFNSTNYVFHFEEEQERGALVGRVFAEDKD-FGPNSEVRYSFETPQSNFELNAITG----VLTSTLQLDRESLMRQRGAAVFSFTVLSSDQGLPKPLKDQAKVQVYIQDINDNPPKFTKDIYQASIAESAQNMT--QLLRV---SASDVDENKNGLVHYDITEGNEEKQFSIDSNSGQVTLVGKLDYETTPSYSLKIIAEDSGSVPLSSTCVLSISVLDDNDNSPSFPKS-TLSVDVLENMRIGELVASVTATDSDSGS--NADITYSI--SATNNHGTFSISPNTGSIFLVKKLDYETQ---SLYKLNVTAKDSGRPSRSSSIPVIIHVRDFNDNPPVFTPGDIFKSIPENLPIST 1421
BLAST of Protocadherin Fat 4 vs. Ensembl Zebrafish
Match: fat1a (FAT atypical cadherin 1a [Source:ZFIN;Acc:ZDB-GENE-050425-1]) HSP 1 Score: 103.605 bits (257), Expect = 2.957e-21 Identity = 197/827 (23.82%), Postives = 354/827 (42.81%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVE--ENILVGSLVGQISVVDEDLDDS--FKCSVKSDS-PFNVDANFNLFT-KAPLDYETQARFEVIIECLDHEN------SSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN-SLSEI--VKIIILNVDENPTDLKLNDSTSNKVLIEENSS-NYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNE-LWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY---FIQLIDVNE-APQG--LTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNE--IFLISQ-FQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDAN-------ERPENLSLSNNQIPENE------PIGLLIAIINAQDNDKNSTLVYTLDVNEKD--FYIE-------NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDN--SRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPP--TKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLN--CNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND 2436 PL+ E+ T++ +L I DL +P+ S ++ V ILDAND + VE E+ VG+ V Q+ D+DL D+ + S+ +D+ F +D + T K PLD E Q F + I D S+V+ K I++ D+N+ P K + + E+ GT I + +DPD S+ V + K +RI L ++E++ D+ SLS +++ +++V+EN L S +K I+E+ S+ +++A DED + I + I +E + + EL + +Y++ D+ ++ ++ +I++ DVN+ APQ YPS V E+ P I + D + S+ EK S ++ + N F I+Q L + +LD E+ + L I V+D G T +I+++ D N E+ + L + PE E P+ +IA + +D N+ + Y+++ ++ F+IE + KL S +D +TI DNG P+ + + IE + E + + + F +ME++ + I+ EP D + +I N SRF V K S + + Q LD EQ +++ + + D + + ++ N P +K + ++++E+ + TD D+ + + Y++L+ + KF G LY E D+E+ + V++R D + V +++QD ND Sbjct: 776 APLDRET-TDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYSVEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGIVTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLK--ITLEDVNDNPPKFIPPNYH----VRVREDLPIGTVIMWLEAHDPDVGP-------SSQVRYSLIDSGDGKFEVDKLSGAVRIVQNL--DYEKKQVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNEN-LYRPLFPSFVDKGFIKEDVPIGTSVMKITAQDEDKGRDGEIRYSIRDGSGLGIFTIDEDTGVIRTQELLDHETVPHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPS-VMESSPKDVSIIQIEAFDPDTKSS-EKLSYKITSGNPQGFFSINQKTGLVTTTSRKLDREQQDEHILEITVSDQGVPAKSTTVRVIVKVLDENDNSPQFMEKVYKIKLPVREKPEKERALKRDPVYRVIA--SDKDEGPNAEISYSIEEGDEQGKFFIEPKTGMVYSKKLSSAVDYD-------ILTIKAVDNGRPQKSTTCRLHIEWIPKPEPSTVPLV--FDEPFYTFSVMESDTVSHMLGVIS-LEP-VDTPVWFEITGGNSDSRFEVGKASGT-------MIVAQALDAEQKSHYNLTVNATDGTRSVSTQVLIKVIDTNNHRPQFSKPKYE------VDVSEDTPPETEVLRITATDQDEKNKLTYTLLSSTDPFSLRKFRLDPGTGVLYTAER--LDHETMHQHTLTVMVRDQDIPVKRNLVRVIVNVQDTND 1555 HSP 2 Score: 88.1965 bits (217), Expect = 1.239e-16 Identity = 161/714 (22.55%), Postives = 283/714 (39.64%), Query Frame = 1 Query: 100 WEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND--PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSP----FNVDANFN-LFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN---SLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEI----KHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFN--KTYFIQLIDVNE-APQ-GLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNE--IFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ--IPENEPIGLLIAIINAQDNDK-NSTLVYTLDV---NEKDFY--IENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELE-MTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGS 2139 W+ S+ PL+ E K N + L I A D + ++ V +LDAND P V E+ G L+ Q+S D D+ + + S + P F++D+ L T PLD E + ++ + LD + EI+V D+N+ P + T + T EN++ T + +Y +D D E + D + ++ + + E QS + TDR + S V + IL++++NP + + T+ + E+ + + A D I++ + +++ E L+YE+++ Y V A + T I L DVN+ +P +Y + ++E+ G + D++ S+ + +I N+ F I + E+K LD EKT Y L + +D G + I +++SD N+ P S +N I EN+PIG + + D D ++ +T + NE DF+ L+S + + Y + V D+G P L + + ++ + P I+ ++F +E I + D D + + D+S SE +F L LD Q + +NI + D + FTA ++ I V T A+D S Sbjct: 2975 WKVSVRKPLDREEKDNYL-LNITATDGTFTAKA---VVEVKVLDANDNSPICEKSFYMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLPLDREEEEVHKMKVRALDGGGRFCEAEVEITVEDVNDNPPQF----TTDPYTFTVFENTEINTPVARLYASDLDTGANAEILYSLLDSADGVFSIEEETGV---------VRLDRPLDRELQSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFERREYTA--TVAEDIPVGTQVLRIHAASRDTEAGTEITYAIINGNERGAFRVDPQTGGVFVIEP--LDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPSS-NQVRFSIIDGNQGSPFTIDPVRGEVKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNPPIFSQANYSIIIQENQPIGASVLQLTVSDRDASHNGPPFTFSIIRGNEGDFFRITPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAFVSVRLIEESIYPPSIL------PLDIFITTATDEYSGGVLGKIHATDQDVYDTLTYSLAPDSS-----STSENSGLFSVSPADGKLVARGNLDAGQ---YVLNITVTDGR-FTAAARVNIHVRQA----TAQALDNS 3647 HSP 3 Score: 85.8853 bits (211), Expect = 6.807e-16 Identity = 49/152 (32.24%), Postives = 69/152 (45.39%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GIC---RDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEF 5631 SN C TC + N + C C F+G + CE I C N CL + CI DF C C SG+ C++ C + C + G C D C C G++G C +D+C+ +PC G C++ F CNC ++G CE Sbjct: 4020 SNPCTNGGTCLALP-NGGYFCKCTAAFMG--THCEVTISPCASNPCLYGGT-CIPRGGDFYCQCRGQYSGQRCQLGP--YCTDNPCKNSGKCIDSLDGPVCECEPGFQGERCLSDVDECLKNPCGNGGHCQNTYGSFSCNCSNGYSGQHCEL 4165 HSP 4 Score: 74.3294 bits (181), Expect = 2.276e-12 Identity = 152/727 (20.91%), Postives = 301/727 (41.40%), Query Frame = 1 Query: 1318 NEIFLISQFQLELKDNTRLDYEKTPAYNLGIRV-TDYGQENIVTDFEIILEISDANE-RPENLSLSNNQ---IPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYI--------ENNKLLSGTVFDHENRPGYQITITVFDNGDP-KLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIF------QYDLTINQTLDYEQNNYFEINIEINDMKNFTA--IMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND-PP--TVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINED---NSFMLTDPLDYETENNFLISFTLIDKNSNQSINLK---VQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGP 3393 +E+F++ LK + +LD+E T Y L ++ ++Y +V+ +I +++ D N+ RP L SN + EN P G + + A D D N +VY LD N++ I E+ + + D E R Y +++ D GD +L S D+ +++ N+NP + Y + E++ A ++ D D + N + IS + + + ++ +++ + LD E+ + + +NI D FTA ++++ + N N P + + + ++ E+ + I TD D N I Y +L + + + G K L D E +KV RA+D GG + EV I+++D ND PP T FT+ + E + + ++ D D + + + FSI + + + R + + + Q + G + S+ + +++I DIN+ P F ++ + +I +G +L +++ + +++ N + D + +PLDYET + F ++ D + +L + + DVN+ + + E + + T A D D S ++ I++G + + V E V ++ + + + +L D+G P+ S + + + ++ND P Sbjct: 2746 DEVFVVDPSSGSLKLDKKLDHESTKWYQLTLQAQSEYEGSKVVSAVDISIQVKDVNDNRP--LFESNPYEAFVVENLPGGTSVIQVKATDLDSGTNGHVVYNLDPNQETRDIVELFAINSESGWITTLKELDRETRNKYTVSVLATDRGDKVQLMASTRVDVTVVDVNDNPPKFTAEIYKGT-----VSEDDPPGGVIAILSTT--DLDTEENNKQIS----YFITGGDPLGQFAIEHTQGEWKVSVRKPLDREEKDNYLLNITATD-GTFTAKAVVEVKVLDANDNSPICEKSF-----YMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLP----LDREEEEVHKMKV--RALDGGGRFCEAEVEITVEDVNDNPPQFTTDPYTFTVFEN-TEINTPVARLYASDLDTGANAEILYSLLDSADGVFSIEEETGVVRLDRPLDREL-QSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFERR---EYTATVAEDIPVGTQVLRIHAASRDTEAGTEITYAIINGNERGAFRVDPQTGGVFVIEPLDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPS--SNQVRFSIIDGNQGSPFTIDPVRGE----VKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNP 3436 HSP 5 Score: 74.3294 bits (181), Expect = 2.295e-12 Identity = 153/680 (22.50%), Postives = 288/680 (42.35%), Query Frame = 1 Query: 1198 LYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI--FLISQFQLELKDNTR--LDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDND--KNSTLVYT-LDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQII-----SDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDM---KNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQ-GYQSIA-NFITTDPDQNDVIKYSILNCLNCNEKFEF----SNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSI-DLE-VPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGK----VNVFDEDNLSTYNQIECSIIKPLKW--FSILNISQNLEIVTTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFS-FNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKS--PPNI 3120 +Y TV+E+ P G VI S D + ++ S + + + F I Q E K + R LD E+ Y L I TD + +++ DAN+ S +PE+ P G LI ++A D D N+ + Y L + F I E +L + D E +++ + D G +I + + N+NP D Y F + EN E+ A + + D D N +I+ S + F +++++ + + +++ LD E + + + + D ++ ++ + + + ++N+ P RE + E+I G Q + + + D + I Y+I +N NE+ F GG +++ E DYE+ + + + A D G S+ DL V I++ D ND V N + + + +D +GK V D D S+ NQ+ SII + F+I + +++ R +D + + + +NG + +S++ + + + DIN+ P FS N+++ + EN +G +L S++ + + I+ NE + F + T L+S + + + + L+ Q+ D P +F ++ + E+S PP+I Sbjct: 2921 IYKGTVSEDDPPGGVIAILSTTDLDTEENNKQISYFITGGDPLGQFAIEHTQGEWKVSVRKPLDREEKDNYLLNITATD---GTFTAKAVVEVKVLDANDNSPICEKSFYMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLPLDREEEEVHKMKVRALDGG--GRFCEAEVEITVEDVNDNPPQFTTDPY-----TFTVFENTEINTPVARL--YASDLDTGANAEILYSLLDSADGVFSIEEETGV-------VRLDRPLDRELQSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFE---RREYTATVAEDIPVGTQVLRIHAASRDTEAGTEITYAI---INGNERGAFRVDPQTGG--VFVIEP--LDYET--AHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPV--FNQDIYSAVISEDAELGKTVLTVMADDADGPSS-NQVRFSIIDGNQGSPFTIDPVRGEVKVA----RLLDREKTSGYTLTVLASDNG-SPARSSSATINVDVSDINDNPPIFSQANYSI-IIQENQ---PIGASVLQLTVSDRDASHNGPPFTFSI-----IRGNEGDFFRI-------TPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAF-VSVRLIEESIYPPSI 3544 HSP 6 Score: 73.559 bits (179), Expect = 3.463e-12 Identity = 176/824 (21.36%), Postives = 335/824 (40.66%), Query Frame = 1 Query: 1516 QIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVN--EKDFYIENNK--LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDK--INCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMK----NFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG---GLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFI-----IG----KVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTY-STALAIEDIN-NEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIK--IQINEDNSFMLT--DPLDYETENNFLISFTLIDKN---SNQSINLKVQILDVNEAPSEI--KSFEKNLTMFEKSPPNIHIATFYATDPDYNQIH-----------SFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDG---PTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNS----YFGISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVN------------------EPPEN--VKISNDQWNEKSEIGLLIANLSANDP 3762 ++ E+ P+G I ++A D+D N LVY + E F I+ + L D E Y + ITV+D G P+ + S+ D++IL++N+N +K+ Y I E++ + + + D D + I++D +F + ++ I +T+ + LD E F + I D + + + I +E+VN+ P K + + E++ I DPD + ++YS+++ + + KFE + + Q DYE + + +A D G LS + + + D N+ L + PSFV+K FI IG K+ DED +I S I+ I I ++ ++ T E + + + +++ + ++D+N N P T + + + ++S+ Q+ + S ++S + S N + IN+ + T LD E ++ ++ T+ D+ + ++ + V++LD N+ + K ++ L + EK P A DP Y I S+ I++ G+ F +V ++ L S+ + Y + I D+G+P S R +I+ I + P + ++ ES ++ +L + +E DT + G NS G ++ ++ +A+ LD E + V D + +VS+ I + D N PPE ++I+ +EK+++ + LS+ DP Sbjct: 723 EVKEDLPVGARIVHLSASDSDSGFNGKLVYVISGGDAESRFIIDMDSGWLKVFAPLDRETTDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYS-----VEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGI-------VTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLKITLEDVNDNPPKFIPPNYH---VRVREDLPIGTVIMWLEAHDPDVGPSSQVRYSLID--SGDGKFEVDKLSGAVRI--VQNLDYEKK--QVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNE-----NLYRPLFPSFVDKGFIKEDVPIGTSVMKITAQDEDK-GRDGEIRYS-IRDGSGLGIFTIDEDTGVIRTQELLDHETVPHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPSVMESSPKDVSIIQIEAFDPDTKSSEKLSYK----ITSGNPQGFFSINQKTGLVTTTSRKLDREQQDEHILEITVSDQGVPAKSTTVRVIVKVLDENDNSPQFMEKVYKIKLPVREK--PEKERA--LKRDPVYRVIASDKDEGPNAEISYSIEEGDEQGKFFIEPKTGMVYSKKL----------SSAVDYDILTIKAVDNGRPQKSTTCRLHIEWIPKPEPSTVPLVFDEPFYTFSVMESDTVSHMLGVISLEPVDTPVWFEITGGNSDSRFEVGKASGTMIVAQALDAEQKSHYNLTVNATDGT-RSVSTQVLIKVIDTNNHRPQFSKPKYEVDVSEDTPPETEVLRITATDQDEKNKLTYTL--LSSTDP 1497 HSP 7 Score: 64.3142 bits (155), Expect = 2.348e-9 Identity = 136/561 (24.24%), Postives = 228/561 (40.64%), Query Frame = 1 Query: 1180 APQGLTLYPST--VTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI---FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPENLSLSNN-QIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDN--GDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQ---IISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMK---NFTAIMKIFIFVENVNE----PPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND--PPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYN-QIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATF 2763 APQ +PS V E++P G+ I S DS+ S + +I+ + F+I LK LD E T Y L I V D G + + ++I DAN+ P+ L + + +I E+ +G + + A+D D N + Y++ + F I E + D E +P + + I D +P+L + I + + N+NP I Y + E+ + + +PD + I S + +F V K S I Q LDYE+ + + + D + ++ I + V +VNE P +D I E++ S+ D D ++ I+YSI + F+ ++ + D+E+ + + A D G LS +EV I +QD ND P T + + + KD I ++ FD D S+ + + P +FS I+Q +VTT +R +D + D +EI + G KSTT + + D N+ F Sbjct: 711 APQFADTFPSVIEVKEDLPVGARIVHLSASDSD--SGFNGKLVYVISGGDAESRFIIDMDSGWLKVFAPLDRETTDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYSVEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGIVTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLKITLEDVNDNPPKFIPPNYH-----VRVREDLPIGTVIMWLEAHDPDVGPSSQVRYSLIDSGDGKFEVDKLSGAVRIV-------QNLDYEKKQVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNENLYRPLFPSFVDKGF-----IKEDVPIGTSVMKITAQDEDKGRDGEIRYSIRDGSGLG---IFTIDEDTGVIRTQELLDHETV--PHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPSVMESSPKDVSIIQIEAFDPDTKSSEKLSYKITSGNPQGFFS---INQKTGLVTTTSRKLDREQQDEHILEITVSDQG-VPAKSTTVRVIVKVLDENDNSPQF 1243 HSP 8 Score: 62.7734 bits (151), Expect = 6.267e-9 Identity = 45/139 (32.37%), Postives = 60/139 (43.17%), Query Frame = 1 Query: 5284 SSCEEIDECLFNFCLGDSSRCIDLVND-FQCLCGSDRSGRTCEVLKVNLCLKSDCVHG---ICRD-DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 S I C N C + C+ L N + C C + G CEV ++ C + C++G I R D C C + G C C +PC G C D+L+G +C C+ F G C D C KN N G C N Sbjct: 4010 SLAPPIQGCTSNPCT-NGGTCLALPNGGYFCKCTAAFMGTHCEV-TISPCASNPCLYGGTCIPRGGDFYCQCRGQYSGQRCQLG-PYCTDNPCKNSGKCIDSLDGPVCECEPGFQGERCLSDVDECLKNPCGNGGHCQN 4145 HSP 9 Score: 59.3066 bits (142), Expect = 6.566e-8 Identity = 107/422 (25.36%), Postives = 178/422 (42.18%), Query Frame = 1 Query: 1372 LDYEKTPAYNLGIRVTDY---GQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKD-----FYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQI----ISDNSR--FLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEIND-MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQN--DVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND-PPTVAGLNFTM-IPSFVEKDFIIGKVNVFDEDNLS 2538 LD+E PAY L +R TD + + D IILE D N+ P + L N + E IG + ++A D D N L Y + V +KD F I+ + +GT++ DHE +P +++ I D G P L+ I++++ N+N + ++ Y AT++ P Q ISD+ + F + +E +N F D L I+ + + IN+ ++D + +AI+K+ + N + PT +D ++ + EN +A TD D + Y I+N + +KF S G L+ D E+ + K I + + A D GG V + + D ND P ++ + + S V + I K+ D D S Sbjct: 2240 LDFETHPAYKLSVRATDSLTGAKAEVFVD--IILE--DVNDNPPVFHTKLYNASLSEASVIGTSVLEVSATDADTGNNKVLFYQI-VEDKDKSFDYFSIDRD---TGTIWTTRMLDHEEKPSHRLLIRAVDGGVPALSSEVMVLIDVMDLNDNTPVFSQNVYE------------------ATVSELAPRGHFVTQVQASDADISDSGKLEFSILSGNEGQN-FAMDPNTGALVISNHRKPHMESLYNINVSVSDGVFRSSAIVKVNVISANFHN-PTFNQVD----YVVELLENSPVGTLVAEAQATDDDSGTYGRLTYHIVNDI-AKDKFSISENGEIFTLES---LDRENALEKVIPISLIAKDGGGKVGFCTVNVILTDINDNAPQFRAADYRVNVASDVSRGTTILKIAASDMDEGS 2625 HSP 10 Score: 58.5362 bits (140), Expect = 1.285e-7 Identity = 84/389 (21.59%), Postives = 157/389 (40.36%), Query Frame = 1 Query: 1141 NKTYFIQLIDVNEAPQGLTL--YPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNT-----RLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDND---KNSTLVYTLDVNEKD-FYIE--NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSE---IKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNE---PPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSI 2244 + T + ++D+N+ P Y +TV E+IP G+ + + + + E + +I NE F+++ + LDYE + L + TD G ++ + + ++D N+ N + + I E+ +G + + A D D N +D N+ F I+ ++ + D E GY +T+ DNG P + S T ++++ + N+NP I + Y I EN + + +TV D D N + F + + +E + Q L TL + ++ + ++ D + F+ V + E PP+ L +D I I + + TD D D + YS+ Sbjct: 3212 HTTVSVSILDINDNPPVFERREYTATVAEDIPVGTQVLRIHAASRDTEAGTE-ITYAIINGNER---GAFRVDPQTGGVFVIEPLDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPSSNQVRFSIIDGNQGSPFTIDPVRGEVKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNPPIFSQANYS-----IIIQENQPIGASVLQLTV--SDRDASHNGPPFT----FSIIRGNEGDFFRITPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAFVSVRLIEESIYPPSILPLD----IFITTATDEYSGGVLGKIHATDQDVYDTLTYSL 3581
BLAST of Protocadherin Fat 4 vs. Ensembl Zebrafish
Match: fat1a (FAT atypical cadherin 1a [Source:ZFIN;Acc:ZDB-GENE-050425-1]) HSP 1 Score: 102.834 bits (255), Expect = 4.538e-21 Identity = 197/827 (23.82%), Postives = 354/827 (42.81%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVE--ENILVGSLVGQISVVDEDLDDS--FKCSVKSDS-PFNVDANFNLFT-KAPLDYETQARFEVIIECLDHEN------SSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN-SLSEI--VKIIILNVDENPTDLKLNDSTSNKVLIEENSS-NYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNE-LWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY---FIQLIDVNE-APQG--LTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNE--IFLISQ-FQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDAN-------ERPENLSLSNNQIPENE------PIGLLIAIINAQDNDKNSTLVYTLDVNEKD--FYIE-------NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDN--SRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPP--TKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLN--CNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND 2436 PL+ E+ T++ +L I DL +P+ S ++ V ILDAND + VE E+ VG+ V Q+ D+DL D+ + S+ +D+ F +D + T K PLD E Q F + I D S+V+ K I++ D+N+ P K + + E+ GT I + +DPD S+ V + K +RI L ++E++ D+ SLS +++ +++V+EN L S +K I+E+ S+ +++A DED + I + I +E + + EL + +Y++ D+ ++ ++ +I++ DVN+ APQ YPS V E+ P I + D + S+ EK S ++ + N F I+Q L + +LD E+ + L I V+D G T +I+++ D N E+ + L + PE E P+ +IA + +D N+ + Y+++ ++ F+IE + KL S +D +TI DNG P+ + + IE + E + + + F +ME++ + I+ EP D + +I N SRF V K S + + Q LD EQ +++ + + D + + ++ N P +K + ++++E+ + TD D+ + + Y++L+ + KF G LY E D+E+ + V++R D + V +++QD ND Sbjct: 776 APLDRET-TDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYSVEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGIVTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLK--ITLEDVNDNPPKFIPPNYH----VRVREDLPIGTVIMWLEAHDPDVGP-------SSQVRYSLIDSGDGKFEVDKLSGAVRIVQNL--DYEKKQVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNEN-LYRPLFPSFVDKGFIKEDVPIGTSVMKITAQDEDKGRDGEIRYSIRDGSGLGIFTIDEDTGVIRTQELLDHETVPHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPS-VMESSPKDVSIIQIEAFDPDTKSS-EKLSYKITSGNPQGFFSINQKTGLVTTTSRKLDREQQDEHILEITVSDQGVPAKSTTVRVIVKVLDENDNSPQFMEKVYKIKLPVREKPEKERALKRDPVYRVIA--SDKDEGPNAEISYSIEEGDEQGKFFIEPKTGMVYSKKLSSAVDYD-------ILTIKAVDNGRPQKSTTCRLHIEWIPKPEPSTVPLV--FDEPFYTFSVMESDTVSHMLGVIS-LEP-VDTPVWFEITGGNSDSRFEVGKASGT-------MIVAQALDAEQKSHYNLTVNATDGTRSVSTQVLIKVIDTNNHRPQFSKPKYE------VDVSEDTPPETEVLRITATDQDEKNKLTYTLLSSTDPFSLRKFRLDPGTGVLYTAER--LDHETMHQHTLTVMVRDQDIPVKRNLVRVIVNVQDTND 1555 HSP 2 Score: 87.8113 bits (216), Expect = 1.705e-16 Identity = 161/714 (22.55%), Postives = 283/714 (39.64%), Query Frame = 1 Query: 100 WEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND--PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSP----FNVDANFN-LFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN---SLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEI----KHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFN--KTYFIQLIDVNE-APQ-GLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNE--IFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ--IPENEPIGLLIAIINAQDNDK-NSTLVYTLDV---NEKDFY--IENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELE-MTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGS 2139 W+ S+ PL+ E K N + L I A D + ++ V +LDAND P V E+ G L+ Q+S D D+ + + S + P F++D+ L T PLD E + ++ + LD + EI+V D+N+ P + T + T EN++ T + +Y +D D E + D + ++ + + E QS + TDR + S V + IL++++NP + + T+ + E+ + + A D I++ + +++ E L+YE+++ Y V A + T I L DVN+ +P +Y + ++E+ G + D++ S+ + +I N+ F I + E+K LD EKT Y L + +D G + I +++SD N+ P S +N I EN+PIG + + D D ++ +T + NE DF+ L+S + + Y + V D+G P L + + ++ + P I+ ++F +E I + D D + + D+S SE +F L LD Q + +NI + D + FTA ++ I V T A+D S Sbjct: 2975 WKVSVRKPLDREEKDNYL-LNITATDGTFTAKA---VVEVKVLDANDNSPICEKSFYMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLPLDREEEEVHKMKVRALDGGGRFCEAEVEITVEDVNDNPPQF----TTDPYTFTVFENTEINTPVARLYASDLDTGANAEILYSLLDSADGVFSIEEETGV---------VRLDRPLDRELQSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFERREYTA--TVAEDIPVGTQVLRIHAASRDTEAGTEITYAIINGNERGAFRVDPQTGGVFVIEP--LDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPSS-NQVRFSIIDGNQGSPFTIDPVRGEVKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNPPIFSQANYSIIIQENQPIGASVLQLTVSDRDASHNGPPFTFSIIRGNEGDFFRITPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAFVSVRLIEESIYPPSIL------PLDIFITTATDEYSGGVLGKIHATDQDVYDTLTYSLAPDSS-----STSENSGLFSVSPADGKLVARGNLDAGQ---YVLNITVTDGR-FTAAARVNIHVRQA----TAQALDNS 3647 HSP 3 Score: 85.8853 bits (211), Expect = 7.100e-16 Identity = 49/152 (32.24%), Postives = 69/152 (45.39%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GIC---RDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEF 5631 SN C TC + N + C C F+G + CE I C N CL + CI DF C C SG+ C++ C + C + G C D C C G++G C +D+C+ +PC G C++ F CNC ++G CE Sbjct: 4023 SNPCTNGGTCLALP-NGGYFCKCTAAFMG--THCEVTISPCASNPCLYGGT-CIPRGGDFYCQCRGQYSGQRCQLGP--YCTDNPCKNSGKCIDSLDGPVCECEPGFQGERCLSDVDECLKNPCGNGGHCQNTYGSFSCNCSNGYSGQHCEL 4168 HSP 4 Score: 73.9442 bits (180), Expect = 2.855e-12 Identity = 153/680 (22.50%), Postives = 288/680 (42.35%), Query Frame = 1 Query: 1198 LYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI--FLISQFQLELKDNTR--LDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDND--KNSTLVYT-LDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQII-----SDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDM---KNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQ-GYQSIA-NFITTDPDQNDVIKYSILNCLNCNEKFEF----SNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSI-DLE-VPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGK----VNVFDEDNLSTYNQIECSIIKPLKW--FSILNISQNLEIVTTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFS-FNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKS--PPNI 3120 +Y TV+E+ P G VI S D + ++ S + + + F I Q E K + R LD E+ Y L I TD + +++ DAN+ S +PE+ P G LI ++A D D N+ + Y L + F I E +L + D E +++ + D G +I + + N+NP D Y F + EN E+ A + + D D N +I+ S + F +++++ + + +++ LD E + + + + D ++ ++ + + + ++N+ P RE + E+I G Q + + + D + I Y+I +N NE+ F GG +++ E DYE+ + + + A D G S+ DL V I++ D ND V N + + + +D +GK V D D S+ NQ+ SII + F+I + +++ R +D + + + +NG + +S++ + + + DIN+ P FS N+++ + EN +G +L S++ + + I+ NE + F + T L+S + + + + L+ Q+ D P +F ++ + E+S PP+I Sbjct: 2921 IYKGTVSEDDPPGGVIAILSTTDLDTEENNKQISYFITGGDPLGQFAIEHTQGEWKVSVRKPLDREEKDNYLLNITATD---GTFTAKAVVEVKVLDANDNSPICEKSFYMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLPLDREEEEVHKMKVRALDGG--GRFCEAEVEITVEDVNDNPPQFTTDPY-----TFTVFENTEINTPVARL--YASDLDTGANAEILYSLLDSADGVFSIEEETGV-------VRLDRPLDRELQSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFE---RREYTATVAEDIPVGTQVLRIHAASRDTEAGTEITYAI---INGNERGAFRVDPQTGG--VFVIEP--LDYET--AHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPV--FNQDIYSAVISEDAELGKTVLTVMADDADGPSS-NQVRFSIIDGNQGSPFTIDPVRGEVKVA----RLLDREKTSGYTLTVLASDNG-SPARSSSATINVDVSDINDNPPIFSQANYSI-IIQENQ---PIGASVLQLTVSDRDASHNGPPFTFSI-----IRGNEGDFFRI-------TPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAF-VSVRLIEESIYPPSI 3544 HSP 5 Score: 73.559 bits (179), Expect = 3.105e-12 Identity = 152/727 (20.91%), Postives = 301/727 (41.40%), Query Frame = 1 Query: 1318 NEIFLISQFQLELKDNTRLDYEKTPAYNLGIRV-TDYGQENIVTDFEIILEISDANE-RPENLSLSNNQ---IPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYI--------ENNKLLSGTVFDHENRPGYQITITVFDNGDP-KLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIF------QYDLTINQTLDYEQNNYFEINIEINDMKNFTA--IMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND-PP--TVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINED---NSFMLTDPLDYETENNFLISFTLIDKNSNQSINLK---VQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGP 3393 +E+F++ LK + +LD+E T Y L ++ ++Y +V+ +I +++ D N+ RP L SN + EN P G + + A D D N +VY LD N++ I E+ + + D E R Y +++ D GD +L S D+ +++ N+NP + Y + E++ A ++ D D + N + IS + + + ++ +++ + LD E+ + + +NI D FTA ++++ + N N P + + + ++ E+ + I TD D N I Y +L + + + G K L D E +KV RA+D GG + EV I+++D ND PP T FT+ + E + + ++ D D + + + FSI + + + R + + + Q + G + S+ + +++I DIN+ P F ++ + +I +G +L +++ + +++ N + D + +PLDYET + F ++ D + +L + + DVN+ + + E + + T A D D S ++ I++G + + V E V ++ + + + +L D+G P+ S + + + ++ND P Sbjct: 2746 DEVFVVDPSSGSLKLDKKLDHESTKWYQLTLQAQSEYEGSKVVSAVDISIQVKDVNDNRP--LFESNPYEAFVVENLPGGTSVIQVKATDLDSGTNGHVVYNLDPNQETRDIVELFAINSESGWITTLKELDRETRNKYTVSVLATDRGDKVQLMASTRVDVTVVDVNDNPPKFTAEIYKGT-----VSEDDPPGGVIAILSTT--DLDTEENNKQIS----YFITGGDPLGQFAIEHTQGEWKVSVRKPLDREEKDNYLLNITATD-GTFTAKAVVEVKVLDANDNSPICEKSF-----YMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLP----LDREEEEVHKMKV--RALDGGGRFCEAEVEITVEDVNDNPPQFTTDPYTFTVFEN-TEINTPVARLYASDLDTGANAEILYSLLDSADGVFSIEEETGVVRLDRPLDREL-QSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFERR---EYTATVAEDIPVGTQVLRIHAASRDTEAGTEITYAIINGNERGAFRVDPQTGGVFVIEPLDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPS--SNQVRFSIIDGNQGSPFTIDPVRGE----VKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNP 3436 HSP 6 Score: 73.1738 bits (178), Expect = 4.530e-12 Identity = 146/670 (21.79%), Postives = 274/670 (40.90%), Query Frame = 1 Query: 1516 QIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVN--EKDFYIENNK--LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDK--INCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNF------TAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG---GLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFI-----IG----KVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTY-STALAIEDIN-NEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIK--IQINEDNSFMLT--DPLDYETENNFLISFTLIDKN---SNQSINLKVQILDVNEAPSEI--KSFEKNLTMFEKSPPNIHIATFYATDPDYNQIH-----------SFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQII 3375 ++ E+ P+G I ++A D+D N LVY + E F I+ + L D E Y + ITV+D G P+ + S+ D++IL++N+N +K+ Y I E++ + + + D D + I++D +F + ++ I +T+ + LD E F + I D T ++KI + E+VN+ P K + + E++ I DPD + ++YS+++ + + KFE + + Q DYE + + +A D G LS + + + D N+ L + PSFV+K FI IG K+ DED +I S I+ I I ++ ++ T E + + + +++ + ++D+N N P T + + + ++S+ Q+ + S ++S + S N + IN+ + T LD E ++ ++ T+ D+ + ++ + V++LD N+ + K ++ L + EK P A DP Y I S+ I++ G+ F +V ++ L S+ + Y + I D+G+P S R +I+ I Sbjct: 723 EVKEDLPVGARIVHLSASDSDSGFNGKLVYVISGGDAESRFIIDMDSGWLKVFAPLDRETTDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYS-----VEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGI-------VTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLKITL--EDVNDNPPKFIPPNYH---VRVREDLPIGTVIMWLEAHDPDVGPSSQVRYSLID--SGDGKFEVDKLSGAVRI--VQNLDYEKK--QVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNE-----NLYRPLFPSFVDKGFIKEDVPIGTSVMKITAQDEDK-GRDGEIRYS-IRDGSGLGIFTIDEDTGVIRTQELLDHETVPHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPSVMESSPKDVSIIQIEAFDPDTKSSEKLSYK----ITSGNPQGFFSINQKTGLVTTTSRKLDREQQDEHILEITVSDQGVPAKSTTVRVIVKVLDENDNSPQFMEKVYKIKLPVREK--PEKERA--LKRDPVYRVIASDKDEGPNAEISYSIEEGDEQGKFFIEPKTGMVYSKKL----------SSAVDYDILTIKAVDNGRPQKSTTCRLHIEWI 1344 HSP 7 Score: 63.929 bits (154), Expect = 2.872e-9 Identity = 136/561 (24.24%), Postives = 228/561 (40.64%), Query Frame = 1 Query: 1180 APQGLTLYPST--VTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI---FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPENLSLSNN-QIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDN--GDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQ---IISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMK---NFTAIMKIFIFVENVNE----PPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND--PPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYN-QIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATF 2763 APQ +PS V E++P G+ I S DS+ S + +I+ + F+I LK LD E T Y L I V D G + + ++I DAN+ P+ L + + +I E+ +G + + A+D D N + Y++ + F I E + D E +P + + I D +P+L + I + + N+NP I Y + E+ + + +PD + I S + +F V K S I Q LDYE+ + + + D + ++ I + V +VNE P +D I E++ S+ D D ++ I+YSI + F+ ++ + D+E+ + + A D G LS +EV I +QD ND P T + + + KD I ++ FD D S+ + + P +FS I+Q +VTT +R +D + D +EI + G KSTT + + D N+ F Sbjct: 711 APQFADTFPSVIEVKEDLPVGARIVHLSASDSD--SGFNGKLVYVISGGDAESRFIIDMDSGWLKVFAPLDRETTDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYSVEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGIVTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLKITLEDVNDNPPKFIPPNYH-----VRVREDLPIGTVIMWLEAHDPDVGPSSQVRYSLIDSGDGKFEVDKLSGAVRIV-------QNLDYEKKQVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNENLYRPLFPSFVDKGF-----IKEDVPIGTSVMKITAQDEDKGRDGEIRYSIRDGSGLG---IFTIDEDTGVIRTQELLDHETV--PHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPSVMESSPKDVSIIQIEAFDPDTKSSEKLSYKITSGNPQGFFS---INQKTGLVTTTSRKLDREQQDEHILEITVSDQG-VPAKSTTVRVIVKVLDENDNSPQF 1243 HSP 8 Score: 62.7734 bits (151), Expect = 6.816e-9 Identity = 45/139 (32.37%), Postives = 60/139 (43.17%), Query Frame = 1 Query: 5284 SSCEEIDECLFNFCLGDSSRCIDLVND-FQCLCGSDRSGRTCEVLKVNLCLKSDCVHG---ICRD-DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 S I C N C + C+ L N + C C + G CEV ++ C + C++G I R D C C + G C C +PC G C D+L+G +C C+ F G C D C KN N G C N Sbjct: 4013 SLAPPIQGCTSNPCT-NGGTCLALPNGGYFCKCTAAFMGTHCEV-TISPCASNPCLYGGTCIPRGGDFYCQCRGQYSGQRCQLG-PYCTDNPCKNSGKCIDSLDGPVCECEPGFQGERCLSDVDECLKNPCGNGGHCQN 4148 HSP 9 Score: 59.3066 bits (142), Expect = 7.573e-8 Identity = 105/419 (25.06%), Postives = 176/419 (42.00%), Query Frame = 1 Query: 1372 LDYEKTPAYNLGIRVTDY---GQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKD-----FYIENNK--LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQI----ISDNSR--FLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEIND-MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQN--DVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND-PPTVAGLNFTM-IPSFVEKDFIIGKVNVFDEDNLS 2538 LD+E PAY L +R TD + + D IILE D N+ P + L N + E IG + ++A D D N L Y + V +KD F I+ + + + + DHE +P +++ I D G P L+ I++++ N+N + ++ Y AT++ P Q ISD+ + F + +E +N F D L I+ + + IN+ ++D + +AI+K+ + N + PT +D ++ + EN +A TD D + Y I+N + +KF S G L+ D E+ + K I + + A D GG V + + D ND P ++ + + S V + I K+ D D S Sbjct: 2240 LDFETHPAYKLSVRATDSLTGAKAEVFVD--IILE--DVNDNPPVFHTKLYNASLSEASVIGTSVLEVSATDADTGNNKVLFYQI-VEDKDKSFDYFSIDRDTGTIWTTRMLDHEEKPSHRLLIRAVDGGVPALSSEVMVLIDVMDLNDNTPVFSQNVYE------------------ATVSELAPRGHFVTQVQASDADISDSGKLEFSILSGNEGQN-FAMDPNTGALVISNHRKPHMESLYNINVSVSDGVFRSSAIVKVNVISANFHN-PTFNQVD----YVVELLENSPVGTLVAEAQATDDDSGTYGRLTYHIVNDI-AKDKFSISENGEIFTLES---LDRENALEKVIPISLIAKDGGGKVGFCTVNVILTDINDNAPQFRAADYRVNVASDVSRGTTILKIAASDMDEGS 2625 HSP 10 Score: 58.151 bits (139), Expect = 1.558e-7 Identity = 84/389 (21.59%), Postives = 157/389 (40.36%), Query Frame = 1 Query: 1141 NKTYFIQLIDVNEAPQGLTL--YPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNT-----RLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDND---KNSTLVYTLDVNEKD-FYIE--NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSE---IKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNE---PPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSI 2244 + T + ++D+N+ P Y +TV E+IP G+ + + + + E + +I NE F+++ + LDYE + L + TD G ++ + + ++D N+ N + + I E+ +G + + A D D N +D N+ F I+ ++ + D E GY +T+ DNG P + S T ++++ + N+NP I + Y I EN + + +TV D D N + F + + +E + Q L TL + ++ + ++ D + F+ V + E PP+ L +D I I + + TD D D + YS+ Sbjct: 3212 HTTVSVSILDINDNPPVFERREYTATVAEDIPVGTQVLRIHAASRDTEAGTE-ITYAIINGNER---GAFRVDPQTGGVFVIEPLDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPSSNQVRFSIIDGNQGSPFTIDPVRGEVKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNPPIFSQANYS-----IIIQENQPIGASVLQLTV--SDRDASHNGPPFT----FSIIRGNEGDFFRITPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAFVSVRLIEESIYPPSILPLD----IFITTATDEYSGGVLGKIHATDQDVYDTLTYSL 3581
BLAST of Protocadherin Fat 4 vs. Ensembl Zebrafish
Match: fat1a (FAT atypical cadherin 1a [Source:ZFIN;Acc:ZDB-GENE-050425-1]) HSP 1 Score: 102.834 bits (255), Expect = 5.018e-21 Identity = 197/827 (23.82%), Postives = 354/827 (42.81%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVE--ENILVGSLVGQISVVDEDLDDS--FKCSVKSDS-PFNVDANFNLFT-KAPLDYETQARFEVIIECLDHEN------SSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN-SLSEI--VKIIILNVDENPTDLKLNDSTSNKVLIEENSS-NYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNE-LWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY---FIQLIDVNE-APQG--LTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNE--IFLISQ-FQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDAN-------ERPENLSLSNNQIPENE------PIGLLIAIINAQDNDKNSTLVYTLDVNEKD--FYIE-------NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDN--SRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPP--TKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLN--CNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND 2436 PL+ E+ T++ +L I DL +P+ S ++ V ILDAND + VE E+ VG+ V Q+ D+DL D+ + S+ +D+ F +D + T K PLD E Q F + I D S+V+ K I++ D+N+ P K + + E+ GT I + +DPD S+ V + K +RI L ++E++ D+ SLS +++ +++V+EN L S +K I+E+ S+ +++A DED + I + I +E + + EL + +Y++ D+ ++ ++ +I++ DVN+ APQ YPS V E+ P I + D + S+ EK S ++ + N F I+Q L + +LD E+ + L I V+D G T +I+++ D N E+ + L + PE E P+ +IA + +D N+ + Y+++ ++ F+IE + KL S +D +TI DNG P+ + + IE + E + + + F +ME++ + I+ EP D + +I N SRF V K S + + Q LD EQ +++ + + D + + ++ N P +K + ++++E+ + TD D+ + + Y++L+ + KF G LY E D+E+ + V++R D + V +++QD ND Sbjct: 776 APLDRET-TDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYSVEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGIVTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLK--ITLEDVNDNPPKFIPPNYH----VRVREDLPIGTVIMWLEAHDPDVGP-------SSQVRYSLIDSGDGKFEVDKLSGAVRIVQNL--DYEKKQVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNEN-LYRPLFPSFVDKGFIKEDVPIGTSVMKITAQDEDKGRDGEIRYSIRDGSGLGIFTIDEDTGVIRTQELLDHETVPHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPS-VMESSPKDVSIIQIEAFDPDTKSS-EKLSYKITSGNPQGFFSINQKTGLVTTTSRKLDREQQDEHILEITVSDQGVPAKSTTVRVIVKVLDENDNSPQFMEKVYKIKLPVREKPEKERALKRDPVYRVIA--SDKDEGPNAEISYSIEEGDEQGKFFIEPKTGMVYSKKLSSAVDYD-------ILTIKAVDNGRPQKSATCRLHIEWIPKPEPSTVPLV--FDEPFYTFSVMESDTVSHMLGVIS-LEP-VDTPVWFEITGGNSDSRFEVGKASGT-------MIVAQALDAEQKSHYNLTVNATDGTRSVSTQVLIKVIDTNNHRPQFSKPKYE------VDVSEDTPPETEVLRITATDQDEKNKLTYTLLSSTDPFSLRKFRLDPGTGVLYTAER--LDHETMHQHTLTVMVRDQDIPVKRNLVRVIVNVQDTND 1555 HSP 2 Score: 87.4261 bits (215), Expect = 1.966e-16 Identity = 161/714 (22.55%), Postives = 283/714 (39.64%), Query Frame = 1 Query: 100 WEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND--PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSP----FNVDANFN-LFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN---SLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEI----KHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFN--KTYFIQLIDVNE-APQ-GLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNE--IFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ--IPENEPIGLLIAIINAQDNDK-NSTLVYTLDV---NEKDFY--IENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELE-MTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGS 2139 W+ S+ PL+ E K N + L I A D + ++ V +LDAND P V E+ G L+ Q+S D D+ + + S + P F++D+ L T PLD E + ++ + LD + EI+V D+N+ P + T + T EN++ T + +Y +D D E + D + ++ + + E QS + TDR + S V + IL++++NP + + T+ + E+ + + A D I++ + +++ E L+YE+++ Y V A + T I L DVN+ +P +Y + ++E+ G + D++ S+ + +I N+ F I + E+K LD EKT Y L + +D G + I +++SD N+ P S +N I EN+PIG + + D D ++ +T + NE DF+ L+S + + Y + V D+G P L + + ++ + P I+ ++F +E I + D D + + D+S SE +F L LD Q + +NI + D + FTA ++ I V T A+D S Sbjct: 2975 WKVSVRKPLDREEKDNYL-LNITATDGTFTAKA---VVEVKVLDANDNSPICEKSFYMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLPLDREEEEVHKMKVRALDGGGRFCEAEVEITVEDVNDNPPQF----TTDPYTFTVFENTEINTPVARLYASDLDTGANAEILYSLLDSADGVFSIEEETGV---------VRLDRPLDRELQSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFERREYTA--TVAEDIPVGTQVLRIHAASRDTEAGTEITYAIINGNERGAFRVDPQTGGVFVIEP--LDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPSS-NQVRFSIIDGNQGSPFTIDPVRGEVKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNPPIFSQANYSIIIQENQPIGASVLQLTVSDRDASHNGPPFTFSIIRGNEGDFFRITPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAFVSVRLIEESIYPPSIL------PLDIFITTATDEYSGGVLGKIHATDQDVYDTLTYSLAPDSS-----STSENSGLFSVSPADGKLVARGNLDAGQ---YVLNITVTDGR-FTAAARVNIHVRQA----TAQALDNS 3647 HSP 3 Score: 85.8853 bits (211), Expect = 7.342e-16 Identity = 49/152 (32.24%), Postives = 69/152 (45.39%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GIC---RDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEF 5631 SN C TC + N + C C F+G + CE I C N CL + CI DF C C SG+ C++ C + C + G C D C C G++G C +D+C+ +PC G C++ F CNC ++G CE Sbjct: 4023 SNPCTNGGTCLALP-NGGYFCKCTAAFMG--THCEVTISPCASNPCLYGGT-CIPRGGDFYCQCRGQYSGQRCQLGP--YCTDNPCKNSGKCIDSLDGPVCECEPGFQGERCLSDVDECLKNPCGNGGHCQNTYGSFSCNCSNGYSGQHCEL 4168 HSP 4 Score: 73.559 bits (179), Expect = 3.434e-12 Identity = 153/680 (22.50%), Postives = 288/680 (42.35%), Query Frame = 1 Query: 1198 LYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI--FLISQFQLELKDNTR--LDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDND--KNSTLVYT-LDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQII-----SDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDM---KNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQ-GYQSIA-NFITTDPDQNDVIKYSILNCLNCNEKFEF----SNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSI-DLE-VPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGK----VNVFDEDNLSTYNQIECSIIKPLKW--FSILNISQNLEIVTTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFS-FNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKS--PPNI 3120 +Y TV+E+ P G VI S D + ++ S + + + F I Q E K + R LD E+ Y L I TD + +++ DAN+ S +PE+ P G LI ++A D D N+ + Y L + F I E +L + D E +++ + D G +I + + N+NP D Y F + EN E+ A + + D D N +I+ S + F +++++ + + +++ LD E + + + + D ++ ++ + + + ++N+ P RE + E+I G Q + + + D + I Y+I +N NE+ F GG +++ E DYE+ + + + A D G S+ DL V I++ D ND V N + + + +D +GK V D D S+ NQ+ SII + F+I + +++ R +D + + + +NG + +S++ + + + DIN+ P FS N+++ + EN +G +L S++ + + I+ NE + F + T L+S + + + + L+ Q+ D P +F ++ + E+S PP+I Sbjct: 2921 IYKGTVSEDDPPGGVIAILSTTDLDTEENNKQISYFITGGDPLGQFAIEHTQGEWKVSVRKPLDREEKDNYLLNITATD---GTFTAKAVVEVKVLDANDNSPICEKSFYMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLPLDREEEEVHKMKVRALDGG--GRFCEAEVEITVEDVNDNPPQFTTDPY-----TFTVFENTEINTPVARL--YASDLDTGANAEILYSLLDSADGVFSIEEETGV-------VRLDRPLDRELQSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFE---RREYTATVAEDIPVGTQVLRIHAASRDTEAGTEITYAI---INGNERGAFRVDPQTGG--VFVIEP--LDYET--AHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPV--FNQDIYSAVISEDAELGKTVLTVMADDADGPSS-NQVRFSIIDGNQGSPFTIDPVRGEVKVA----RLLDREKTSGYTLTVLASDNG-SPARSSSATINVDVSDINDNPPIFSQANYSI-IIQENQ---PIGASVLQLTVSDRDASHNGPPFTFSI-----IRGNEGDFFRI-------TPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAF-VSVRLIEESIYPPSI 3544 HSP 5 Score: 73.559 bits (179), Expect = 3.551e-12 Identity = 152/727 (20.91%), Postives = 301/727 (41.40%), Query Frame = 1 Query: 1318 NEIFLISQFQLELKDNTRLDYEKTPAYNLGIRV-TDYGQENIVTDFEIILEISDANE-RPENLSLSNNQ---IPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYI--------ENNKLLSGTVFDHENRPGYQITITVFDNGDP-KLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIF------QYDLTINQTLDYEQNNYFEINIEINDMKNFTA--IMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND-PP--TVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINED---NSFMLTDPLDYETENNFLISFTLIDKNSNQSINLK---VQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGP 3393 +E+F++ LK + +LD+E T Y L ++ ++Y +V+ +I +++ D N+ RP L SN + EN P G + + A D D N +VY LD N++ I E+ + + D E R Y +++ D GD +L S D+ +++ N+NP + Y + E++ A ++ D D + N + IS + + + ++ +++ + LD E+ + + +NI D FTA ++++ + N N P + + + ++ E+ + I TD D N I Y +L + + + G K L D E +KV RA+D GG + EV I+++D ND PP T FT+ + E + + ++ D D + + + FSI + + + R + + + Q + G + S+ + +++I DIN+ P F ++ + +I +G +L +++ + +++ N + D + +PLDYET + F ++ D + +L + + DVN+ + + E + + T A D D S ++ I++G + + V E V ++ + + + +L D+G P+ S + + + ++ND P Sbjct: 2746 DEVFVVDPSSGSLKLDKKLDHESTKWYQLTLQAQSEYEGSKVVSAVDISIQVKDVNDNRP--LFESNPYEAFVVENLPGGTSVIQVKATDLDSGTNGHVVYNLDPNQETRDIVELFAINSESGWITTLKELDRETRNKYTVSVLATDRGDKVQLMASTRVDVTVVDVNDNPPKFTAEIYKGT-----VSEDDPPGGVIAILSTT--DLDTEENNKQIS----YFITGGDPLGQFAIEHTQGEWKVSVRKPLDREEKDNYLLNITATD-GTFTAKAVVEVKVLDANDNSPICEKSF-----YMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLP----LDREEEEVHKMKV--RALDGGGRFCEAEVEITVEDVNDNPPQFTTDPYTFTVFEN-TEINTPVARLYASDLDTGANAEILYSLLDSADGVFSIEEETGVVRLDRPLDREL-QSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFERR---EYTATVAEDIPVGTQVLRIHAASRDTEAGTEITYAIINGNERGAFRVDPQTGGVFVIEPLDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPS--SNQVRFSIIDGNQGSPFTIDPVRGE----VKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNP 3436 HSP 6 Score: 73.1738 bits (178), Expect = 5.224e-12 Identity = 146/670 (21.79%), Postives = 274/670 (40.90%), Query Frame = 1 Query: 1516 QIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVN--EKDFYIENNK--LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDK--INCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNF------TAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG---GLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFI-----IG----KVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTY-STALAIEDIN-NEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIK--IQINEDNSFMLT--DPLDYETENNFLISFTLIDKN---SNQSINLKVQILDVNEAPSEI--KSFEKNLTMFEKSPPNIHIATFYATDPDYNQIH-----------SFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQII 3375 ++ E+ P+G I ++A D+D N LVY + E F I+ + L D E Y + ITV+D G P+ + S+ D++IL++N+N +K+ Y I E++ + + + D D + I++D +F + ++ I +T+ + LD E F + I D T ++KI + E+VN+ P K + + E++ I DPD + ++YS+++ + + KFE + + Q DYE + + +A D G LS + + + D N+ L + PSFV+K FI IG K+ DED +I S I+ I I ++ ++ T E + + + +++ + ++D+N N P T + + + ++S+ Q+ + S ++S + S N + IN+ + T LD E ++ ++ T+ D+ + ++ + V++LD N+ + K ++ L + EK P A DP Y I S+ I++ G+ F +V ++ L S+ + Y + I D+G+P S R +I+ I Sbjct: 723 EVKEDLPVGARIVHLSASDSDSGFNGKLVYVISGGDAESRFIIDMDSGWLKVFAPLDRETTDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYS-----VEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGI-------VTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLKITL--EDVNDNPPKFIPPNYH---VRVREDLPIGTVIMWLEAHDPDVGPSSQVRYSLID--SGDGKFEVDKLSGAVRI--VQNLDYEKK--QVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNE-----NLYRPLFPSFVDKGFIKEDVPIGTSVMKITAQDEDK-GRDGEIRYS-IRDGSGLGIFTIDEDTGVIRTQELLDHETVPHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPSVMESSPKDVSIIQIEAFDPDTKSSEKLSYK----ITSGNPQGFFSINQKTGLVTTTSRKLDREQQDEHILEITVSDQGVPAKSTTVRVIVKVLDENDNSPQFMEKVYKIKLPVREK--PEKERA--LKRDPVYRVIASDKDEGPNAEISYSIEEGDEQGKFFIEPKTGMVYSKKL----------SSAVDYDILTIKAVDNGRPQKSATCRLHIEWI 1344 HSP 7 Score: 63.5438 bits (153), Expect = 3.397e-9 Identity = 136/561 (24.24%), Postives = 228/561 (40.64%), Query Frame = 1 Query: 1180 APQGLTLYPST--VTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI---FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPENLSLSNN-QIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDN--GDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQ---IISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMK---NFTAIMKIFIFVENVNE----PPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND--PPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYN-QIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATF 2763 APQ +PS V E++P G+ I S DS+ S + +I+ + F+I LK LD E T Y L I V D G + + ++I DAN+ P+ L + + +I E+ +G + + A+D D N + Y++ + F I E + D E +P + + I D +P+L + I + + N+NP I Y + E+ + + +PD + I S + +F V K S I Q LDYE+ + + + D + ++ I + V +VNE P +D I E++ S+ D D ++ I+YSI + F+ ++ + D+E+ + + A D G LS +EV I +QD ND P T + + + KD I ++ FD D S+ + + P +FS I+Q +VTT +R +D + D +EI + G KSTT + + D N+ F Sbjct: 711 APQFADTFPSVIEVKEDLPVGARIVHLSASDSD--SGFNGKLVYVISGGDAESRFIIDMDSGWLKVFAPLDRETTDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYSVEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGIVTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLKITLEDVNDNPPKFIPPNYH-----VRVREDLPIGTVIMWLEAHDPDVGPSSQVRYSLIDSGDGKFEVDKLSGAVRIV-------QNLDYEKKQVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNENLYRPLFPSFVDKGF-----IKEDVPIGTSVMKITAQDEDKGRDGEIRYSIRDGSGLG---IFTIDEDTGVIRTQELLDHETV--PHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPSVMESSPKDVSIIQIEAFDPDTKSSEKLSYKITSGNPQGFFS---INQKTGLVTTTSRKLDREQQDEHILEITVSDQG-VPAKSTTVRVIVKVLDENDNSPQF 1243 HSP 8 Score: 62.7734 bits (151), Expect = 7.049e-9 Identity = 45/139 (32.37%), Postives = 60/139 (43.17%), Query Frame = 1 Query: 5284 SSCEEIDECLFNFCLGDSSRCIDLVND-FQCLCGSDRSGRTCEVLKVNLCLKSDCVHG---ICRD-DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 S I C N C + C+ L N + C C + G CEV ++ C + C++G I R D C C + G C C +PC G C D+L+G +C C+ F G C D C KN N G C N Sbjct: 4013 SLAPPIQGCTSNPCT-NGGTCLALPNGGYFCKCTAAFMGTHCEV-TISPCASNPCLYGGTCIPRGGDFYCQCRGQYSGQRCQLG-PYCTDNPCKNSGKCIDSLDGPVCECEPGFQGERCLSDVDECLKNPCGNGGHCQN 4148 HSP 9 Score: 58.9214 bits (141), Expect = 8.588e-8 Identity = 105/419 (25.06%), Postives = 176/419 (42.00%), Query Frame = 1 Query: 1372 LDYEKTPAYNLGIRVTDY---GQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKD-----FYIENNK--LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQI----ISDNSR--FLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEIND-MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQN--DVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND-PPTVAGLNFTM-IPSFVEKDFIIGKVNVFDEDNLS 2538 LD+E PAY L +R TD + + D IILE D N+ P + L N + E IG + ++A D D N L Y + V +KD F I+ + + + + DHE +P +++ I D G P L+ I++++ N+N + ++ Y AT++ P Q ISD+ + F + +E +N F D L I+ + + IN+ ++D + +AI+K+ + N + PT +D ++ + EN +A TD D + Y I+N + +KF S G L+ D E+ + K I + + A D GG V + + D ND P ++ + + S V + I K+ D D S Sbjct: 2240 LDFETHPAYKLSVRATDSLTGAKAEVFVD--IILE--DVNDNPPVFHTKLYNASLSEASVIGTSVLEVSATDADTGNNKVLFYQI-VEDKDKSFDYFSIDRDTGTIWTTRMLDHEEKPSHRLLIRAVDGGVPALSSEVMVLIDVMDLNDNTPVFSQNVYE------------------ATVSELAPRGHFVTQVQASDADISDSGKLEFSILSGNEGQN-FAMDPNTGALVISNHRKPHMESLYNINVSVSDGVFRSSAIVKVNVISANFHN-PTFNQVD----YVVELLENSPVGTLVAEAQATDDDSGTYGRLTYHIVNDI-AKDKFSISENGEIFTLES---LDRENALEKVIPISLIAKDGGGKVGFCTVNVILTDINDNAPQFRAADYRVNVASDVSRGTTILKIAASDMDEGS 2625 HSP 10 Score: 58.151 bits (139), Expect = 1.680e-7 Identity = 84/389 (21.59%), Postives = 157/389 (40.36%), Query Frame = 1 Query: 1141 NKTYFIQLIDVNEAPQGLTL--YPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNT-----RLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDND---KNSTLVYTLDVNEKD-FYIE--NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSE---IKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNE---PPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSI 2244 + T + ++D+N+ P Y +TV E+IP G+ + + + + E + +I NE F+++ + LDYE + L + TD G ++ + + ++D N+ N + + I E+ +G + + A D D N +D N+ F I+ ++ + D E GY +T+ DNG P + S T ++++ + N+NP I + Y I EN + + +TV D D N + F + + +E + Q L TL + ++ + ++ D + F+ V + E PP+ L +D I I + + TD D D + YS+ Sbjct: 3212 HTTVSVSILDINDNPPVFERREYTATVAEDIPVGTQVLRIHAASRDTEAGTE-ITYAIINGNER---GAFRVDPQTGGVFVIEPLDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPSSNQVRFSIIDGNQGSPFTIDPVRGEVKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNPPIFSQANYS-----IIIQENQPIGASVLQLTV--SDRDASHNGPPFT----FSIIRGNEGDFFRITPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAFVSVRLIEESIYPPSILPLD----IFITTATDEYSGGVLGKIHATDQDVYDTLTYSL 3581
BLAST of Protocadherin Fat 4 vs. Ensembl Xenopus
Match: NOTCH3 (notch 3 [Source:NCBI gene;Acc:100494244]) HSP 1 Score: 110.923 bits (276), Expect = 2.057e-23 Identity = 67/186 (36.02%), Postives = 98/186 (52.69%), Query Frame = 1 Query: 5167 GISICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKN 5691 G +CH SN CH++A C +N +N C C PGF G G+ +++DEC N C RC++ FQC CG +G CE VN CL + C + C D + +C+C++G+ G C +I++C PC GVC+D +NGF C+C FTG C+ D C + +N C++ N Sbjct: 297 GCLLCHLEDACVSNPCHKDAMCDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPC-EHFGRCVNTQGSFQCQCGRGYTGPRCET-DVNECLSTPCQNDATCLDRIGEFTCICMAGFTGTFCELNINECESSPCVNGGVCKDVVNGFTCSCPAGFTGSMCQIDIDECASTPCKNGAKCVDRPN 479 HSP 2 Score: 94.3597 bits (233), Expect = 2.015e-18 Identity = 60/175 (34.29%), Postives = 83/175 (47.43%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLNLK 5688 SN C A C + N + C C PG+ G SC +IDEC + +C++ F+C C S +G+ CE + V C S C +G CR C CL G+EG +C ++DDC G C G C D +N + C C +TG +C D C+ N N G C N + Sbjct: 76 SNPCENGARCTN--WNGRYNCTCPPGY--QGRSCRVDIDECRTPGLCQNGGQCVNTPGSFRCRCPSGYTGQFCEAIYVP-CAPSQCQNGGTCRQTGDLTYQCACLPGFEGPNCEINVDDCPGHKCMNGGTCVDGVNTYNCQCAPEWTGQYCTEDVDECQLQPNACHNGGTCFNTQ 245 HSP 3 Score: 75.8702 bits (185), Expect = 9.790e-13 Identity = 48/169 (28.40%), Postives = 79/169 (46.75%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH--GIC---RDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTG--IFCEFDHFSCKNCSENFGVC 5676 ++C TC+ + +QC C PGF G +CE +D+C + C+ + C+D VN + C C + +G+ C L+ + H G C + ++C+C++GW G C+++IDDC C C D + F C C TG + C + N +C Sbjct: 154 SQCQNGGTCRQTG-DLTYQCACLPGF--EGPNCEINVDDCPGHKCM-NGGTCVDGVNTYNCQCAPEWTGQYCTEDVDECQLQPNACHNGGTCFNTQGGHTCVCVNGWTGESCSENIDDCATAVCFNGATCHDRVASFYCECPMGKTGGCLLCHLEDACVSNPCHKDAMC 318 HSP 4 Score: 74.3294 bits (181), Expect = 2.970e-12 Identity = 60/217 (27.65%), Postives = 91/217 (41.94%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVND-------------------------------------FQCLCGSDRSGRTCEVLKVNL-------CLKSDCV---HGICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN-CSENFGVCLNL 5685 N N C CK + F C C PGF G+ + +EI+ECL N C + + C D VN F+C C + +G C+V +V+ +++D + GIC + S C+C G+ G C I+ C DPC+ G C L G++C C + G CE+D C++ +N G C++L Sbjct: 791 NPNPCLNGGACKDGI--NSFACSCIPGFTGSRCT-DEINECLSNPCR-NGATCKDYVNSYVCSCFYSLWLFLQNLVDLCRRSPCQNGGRCTQTGPSFRCECPAGWAGSYCDVPRVSCEVAAARRNVRADQLCHSGGICMNAGSSHHCICRGGYTGSYCENPINQCDPDPCHNGGACHSYLGGYVCECPSGYEGKNCEYDINECQSHPCQNGGTCIDL 1003 HSP 5 Score: 73.1738 bits (178), Expect = 5.819e-12 Identity = 54/197 (27.41%), Postives = 87/197 (44.16%), Query Frame = 1 Query: 5173 SICHFNSNKCHRN-----ATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDR--------------SGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 + C N N+C + CK ++ + F C C GF GS C+ +IDEC C + ++C+D N ++C C G C+ ++ C C HG CRD +C C G+ G C I++C +PC G C D +N ++C C + CE ++ C + ++G C + N+ Sbjct: 416 TFCELNINECESSPCVNGGVCK--DVVNGFTCSCPAGF--TGSMCQIDIDECASTPC-KNGAKCVDRPNGYECRCAEGEFCAQGYLTVGNLTPGGPLCD-RNIDDCSPDPCHHGKCRDGIASFTCTCEPGYTGYRCENQINECHSNPCMHGGKCIDLVNKYLCYC------VHCEHNYDDCASNPCDYGECRDGINR 600 HSP 6 Score: 70.8626 bits (172), Expect = 3.101e-11 Identity = 53/170 (31.18%), Postives = 72/170 (42.35%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVG-----NGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICR------DDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN---GFICNCQQNFTGIFCEFDHFSCKNCS 5658 S+ C TC +L + C C PG +G N C + CL + + CID V ++C C +G CE +N CL C R +D C+C SG+ G C ++ C PC GVC +N G+ C C FTG CE SC+ S Sbjct: 991 SHPCQNGGTCI--DLIGRYICSCPPGTLGVLCEINEDDCSPLSISGPPKCLNNGT-CIDKVGGYRCNCPPGYTGERCEG-DINECLSGPCHAQNTRHCVQLANDYQCVCKSGYTGRRCQSVMNTCESRPCQNGGVCSVTVNTPLGYTCRCPLGFTGPSCERPPLSCRELS 1156 HSP 7 Score: 68.5514 bits (166), Expect = 1.638e-10 Identity = 52/177 (29.38%), Postives = 75/177 (42.37%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS------CLCLSGWEGIDCNKSIDDC-IG-DPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLN 5682 C N CH TC + + C C G+ G S E ID+C C + + C D V F C C ++G + C+ + C D N C C G+ G C++ +D+C IG +PC G C + F C C + +TG CE D C + +N CL+ Sbjct: 228 CQLQPNACHNGGTCFNTQ--GGHTCVCVNGWTGESCS-ENIDDCATAVCF-NGATCHDRVASFYCECPMGKTGGCLLCHLEDACVSNPCHKDAMCDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHFGRCVNTQGSFQCQCGRGYTGPRCETDVNECLSTPCQNDATCLD 400 HSP 8 Score: 67.781 bits (164), Expect = 2.806e-10 Identity = 54/155 (34.84%), Postives = 69/155 (44.52%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCEEI-DECLFNFCL--GDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKN 5691 C C GF G CE I D C + C G S D C C G TC+ ++ C +S C +G C + SC CLSG+ G DC I+DC +PC G C+D +N F C+C FTG C + C N N C + N Sbjct: 694 CRCRDGF--RGQKCETILDPCAPDPCHNGGICSPTPDY-ESHMCQCSPGWRGETCDD-DIDECARSPCKNGGFCTNMQGGYSCACLSGFNGQDCETDINDCNPNPCLNGGACKDGINSFACSCIPGFTGSRCTDEINECLSNPCRNGATCKDYVN 844 HSP 9 Score: 60.4622 bits (145), Expect = 4.313e-8 Identity = 53/171 (30.99%), Postives = 74/171 (43.27%), Query Frame = 1 Query: 5167 GISICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLC-GSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSC--LCLSGWEGID------CNKSIDDCIGDPCNGRGVCEDALNGF----ICNCQQNFTGIFCE 5628 G +C N + C + C + D F C C PG+ G CE +I+EC N C+ +CIDLVN + C C + + C N C +C GI R D C C +G CN + C +PC G C+ NGF C+C+ +TG C+ Sbjct: 504 GGPLCDRNIDDCSPDP-CHHGKCRDGIASFTCTCEPGY--TGYRCENQINECHSNPCM-HGGKCIDLVNKYLCYCVHCEHNYDDC---ASNPCDYGECRDGINRYDCVCKQRCNNGGNLTQKNSCPLCNIEVSPCASNPCRAGGTCQVTQNGFRCLYSCDCKVGWTGRMCD 667 HSP 10 Score: 57.3806 bits (137), Expect = 3.804e-7 Identity = 39/128 (30.47%), Postives = 56/128 (43.75%), Query Frame = 1 Query: 5344 CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKNKNQYCLD 5712 C++ + C+C +G CE +N C C +G C C C SG+EG +C I++C PC G C D + +IC+C G+ CE + C S CLN N C+D Sbjct: 924 CMNAGSSHHCICRGGYTGSYCEN-PINQCDPDPCHNGGACHSYLGGYVCECPSGYEGKNCEYDINECQSHPCQNGGTCIDLIGRYICSCPPGTLGVLCEINEDDCSPLSISGPPKCLN----NGTCID 1046
BLAST of Protocadherin Fat 4 vs. Ensembl Xenopus
Match: NOTCH3 (notch 3 [Source:NCBI gene;Acc:100494244]) HSP 1 Score: 110.538 bits (275), Expect = 2.666e-23 Identity = 66/183 (36.07%), Postives = 97/183 (53.01%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKN 5691 +CH SN CH++A C +N +N C C PGF G G+ +++DEC N C RC++ FQC CG +G CE VN CL + C + C D + +C+C++G+ G C +I++C PC GVC+D +NGF C+C FTG C+ D C + +N C++ N Sbjct: 220 LCHLEDACVSNPCHKDAMCDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPC-EHFGRCVNTQGSFQCQCGRGYTGPRCET-DVNECLSTPCQNDATCLDRIGEFTCICMAGFTGTFCELNINECESSPCVNGGVCKDVVNGFTCSCPAGFTGSMCQIDIDECASTPCKNGAKCVDRPN 399 HSP 2 Score: 94.3597 bits (233), Expect = 2.166e-18 Identity = 57/183 (31.15%), Postives = 91/183 (49.73%), Query Frame = 1 Query: 5173 SICHFNSNKCHRN-----ATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 + C N N+C + CK ++ + F C C GF GS C+ +IDEC C + ++C+D N ++C C G C+ ++ C C HG CRD +C C G+ G C I++C +PC G C D +N ++C CQQ +G+ CE ++ C + ++G C + N+ Sbjct: 336 TFCELNINECESSPCVNGGVCK--DVVNGFTCSCPAGF--TGSMCQIDIDECASTPC-KNGAKCVDRPNGYECRCAEGFEGPLCD-RNIDDCSPDPCHHGKCRDGIASFTCTCEPGYTGYRCENQINECHSNPCMHGGKCIDLVNKYLCYCQQGTSGVHCEHNYDDCASNPCDYGECRDGINR 512 HSP 3 Score: 85.8853 bits (211), Expect = 7.739e-16 Identity = 50/169 (29.59%), Postives = 85/169 (50.30%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLN 5682 + CH C + C C+PG+ G +C++ IDEC + C + C ++ + C C S +G+ CE +N C + C++G C+D +C C+ G+ G C I++C+ +PC C+D +N ++C+C +TG CE + C S N G C++ Sbjct: 693 DPCHNGGICSPTPDYESHMCQCSPGW--RGETCDDDIDECARSPC-KNGGFCTNMQGGYSCACLSGFNGQDCET-DINDCNPNPCLNGGACKDGINSFACSCIPGFTGSRCTDEINECLSNPCRNGATCKDYVNSYVCSCAPGYTGPICETNIQDCTESSCFNGGTCVD 857 HSP 4 Score: 83.1889 bits (204), Expect = 5.220e-15 Identity = 50/151 (33.11%), Postives = 71/151 (47.02%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 N N C CK + F C C PGF G+ + +EI+ECL N C + + C D VN + C C +G CE + C +S C +G C D +C C G+ G C +D+C PC +C D + + C C +TG C+ Sbjct: 769 NPNPCLNGGACKDGI--NSFACSCIPGFTGSRCT-DEINECLSNPCR-NGATCKDYVNSYVCSCAPGYTGPICET-NIQDCTESSCFNGGTCVDGVNSYTCRCRPGFTGSHCQNEVDECASRPCQNGAMCVDGVESYRCICPYGYTGAQCQ 914 HSP 5 Score: 80.1073 bits (196), Expect = 4.271e-14 Identity = 52/150 (34.67%), Postives = 72/150 (48.00%), Query Frame = 1 Query: 5176 ICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQ 5604 +C N + C + C + D F C C PG+ G CE +I+EC N C+ +CIDLVN + C C SG CE + C + C +G CRD C+C +G+ G CN + C +PC G C+ NGF C C + Sbjct: 413 LCDRNIDDCSPDP-CHHGKCRDGIASFTCTCEPGY--TGYRCENQINECHSNPCM-HGGKCIDLVNKYLCYCQQGTSGVHCE-HNYDDCASNPCDYGECRDGINRYDCVCKAGFTGPLCNIEVSPCASNPCRAGGTCQVTQNGFRCLCPE 557 HSP 6 Score: 77.0258 bits (188), Expect = 3.675e-13 Identity = 57/179 (31.84%), Postives = 86/179 (48.04%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKS----NELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC--EFDHFSCKNCSENFGVCLN 5682 C + ++C R + CK+ + + C C GF NG CE +I++C N CL + C D +N F C C +G C ++N CL + C +G C+D C C G+ G C +I DC C G C D +N + C C+ FTG C E D + + C +N +C++ Sbjct: 723 CDDDIDECAR-SPCKNGGFCTNMQGGYSCACLSGF--NGQDCETDINDCNPNPCL-NGGACKDGINSFACSCIPGFTGSRC-TDEINECLSNPCRNGATCKDYVNSYVCSCAPGYTGPICETNIQDCTESSCFNGGTCVDGVNSYTCRCRPGFTGSHCQNEVDECASRPC-QNGAMCVD 895 HSP 7 Score: 77.0258 bits (188), Expect = 3.998e-13 Identity = 60/227 (26.43%), Postives = 90/227 (39.65%), Query Frame = 1 Query: 5176 ICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-------------------------------------------------ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN-CSENFGVCLNL 5685 IC N C ++ D + C C PGF GS C+ E+DEC C + + C+D V ++C+C +G C+ L V+LC +S C +G IC + S C+C G+ G C I+ C DPC+ G C L G++C C + G CE+D C++ +N G C++L Sbjct: 836 ICETNIQDCTESSCFNGGTCVDGVNSYTCRCRPGF--TGSHCQNEVDECASRPC-QNGAMCVDGVESYRCICPYGYTGAQCQNL-VDLCRRSPCQNGGRCTQTGPSFRCECPAGWAGSYCDVPRVSCEVAAARRNVRADQLCHSGGICMNAGSSHHCICRGGYTGSYCENPINQCDPDPCHNGGACHSYLGGYVCECPSGYEGKNCEYDINECQSHPCQNGGTCIDL 1058 HSP 8 Score: 76.6406 bits (187), Expect = 6.087e-13 Identity = 44/152 (28.95%), Postives = 73/152 (48.03%), Query Frame = 1 Query: 5242 EFQCFCNPGFVG-NGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH--GIC---RDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 +++C C GF G G +CE +D+C + C+ + C+D VN + C C + +G+ C L+ + H G C + ++C+C++GW G C+++IDDC C C D + F C C TG+ C + N +C Sbjct: 88 QYECSCAKGFRGFEGPNCEINVDDCPGHKCM-NGGTCVDGVNTYNCQCAPEWTGQYCTEDVDECQLQPNACHNGGTCFNTQGGHTCVCVNGWTGESCSENIDDCATAVCFNGATCHDRVASFYCECPMGKTGLLCHLEDACVSNPCHKDAMC 238 HSP 9 Score: 72.0182 bits (175), Expect = 1.214e-11 Identity = 51/167 (30.54%), Postives = 79/167 (47.31%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSN----ELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 S+C + ++C + CK+ + + ++C C GF G C+ ID+C + C +C D + F C C +G CE ++N C + C+HG C D C C G G+ C + DDC +PC+ G C D +N + C C+ FTG C + C Sbjct: 374 SMCQIDIDEC-ASTPCKNGAKCVDRPNGYECRCAEGF--EGPLCDRNIDDCSPDPC--HHGKCRDGIASFTCTCEPGYTGYRCEN-QINECHSNPCMHGGKCIDLVNKYLCYCQQGTSGVHCEHNYDDCASNPCD-YGECRDGINRYDCVCKAGFTGPLCNIEVSPC 533 HSP 10 Score: 71.2478 bits (173), Expect = 2.608e-11 Identity = 53/170 (31.18%), Postives = 72/170 (42.35%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVG-----NGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICR------DDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN---GFICNCQQNFTGIFCEFDHFSCKNCS 5658 S+ C TC +L + C C PG +G N C + CL + + CID V ++C C +G CE +N CL C R +D C+C SG+ G C ++ C PC GVC +N G+ C C FTG CE SC+ S Sbjct: 1046 SHPCQNGGTCI--DLIGRYICSCPPGTLGVLCEINEDDCSPLSISGPPKCLNNGT-CIDKVGGYRCNCPPGYTGERCEG-DINECLSGPCHAQNTRHCVQLANDYQCVCKSGYTGRRCQSVMNTCESRPCQNGGVCSVTVNTPLGYTCRCPLGFTGPSCERPPLSCRELS 1211 HSP 11 Score: 70.4774 bits (171), Expect = 4.142e-11 Identity = 55/192 (28.65%), Postives = 78/192 (40.62%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVL---------------------------------------KVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKN 5691 C C GF G +C +IDEC CL + +C+D + + CLC +G+ CE + ++ C +S C +G C + SC CLSG+ G DC I+DC +PC G C+D +N F C+C FTG C + C N N C + N Sbjct: 634 CRCRDGF--RGPTCMIDIDECASAPCL-NGGKCMDGIAGYSCLCTLPYTGQKCETILDPCAPDPCHNGGICSPTPDYESHMCQCSPGWRGETCDDDIDECARSPCKNGGFCTNMQGGYSCACLSGFNGQDCETDINDCNPNPCLNGGACKDGINSFACSCIPGFTGSRCTDEINECLSNPCRNGATCKDYVN 822 HSP 12 Score: 59.6918 bits (143), Expect = 8.126e-8 Identity = 47/169 (27.81%), Postives = 67/169 (39.64%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSR--CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVC 5676 SN C TC+ + + F+C C G C + C C L + + C C +GR C+ ++C + C +G C D C C G+ G C ID+C PC G C D + G+ C C +TG CE C + N G+C Sbjct: 535 SNPCRAGGTCQVTQ--NGFRCLCPEGRGTRDFLCNPTQDPDKELCPPGCVHGVCRRLSDGYSCDCKVGWTGRMCDRRGSDVCTPNPCQNGGNCIDHQGVPICRCRDGFRGPTCMIDIDECASAPCLNGGKCMDGIAGYSCLCTLPYTGQKCETILDPCAPDPCHNGGIC 701 HSP 13 Score: 57.7658 bits (138), Expect = 3.252e-7 Identity = 39/128 (30.47%), Postives = 56/128 (43.75%), Query Frame = 1 Query: 5344 CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKNKNQYCLD 5712 C++ + C+C +G CE +N C C +G C C C SG+EG +C I++C PC G C D + +IC+C G+ CE + C S CLN N C+D Sbjct: 979 CMNAGSSHHCICRGGYTGSYCEN-PINQCDPDPCHNGGACHSYLGGYVCECPSGYEGKNCEYDINECQSHPCQNGGTCIDLIGRYICSCPPGTLGVLCEINEDDCSPLSISGPPKCLN----NGTCID 1101
BLAST of Protocadherin Fat 4 vs. Ensembl Xenopus
Match: NOTCH3 (notch 3 [Source:NCBI gene;Acc:100494244]) HSP 1 Score: 110.153 bits (274), Expect = 3.875e-23 Identity = 66/183 (36.07%), Postives = 97/183 (53.01%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKN 5691 +CH SN CH++A C +N +N C C PGF G G+ +++DEC N C RC++ FQC CG +G CE VN CL + C + C D + +C+C++G+ G C +I++C PC GVC+D +NGF C+C FTG C+ D C + +N C++ N Sbjct: 332 LCHLEDACVSNPCHKDAMCDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPC-EHFGRCVNTQGSFQCQCGRGYTGPRCET-DVNECLSTPCQNDATCLDRIGEFTCICMAGFTGTFCELNINECESSPCVNGGVCKDVVNGFTCSCPAGFTGSMCQIDIDECASTPCKNGAKCVDRPN 511 HSP 2 Score: 94.3597 bits (233), Expect = 2.170e-18 Identity = 60/175 (34.29%), Postives = 83/175 (47.43%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLNLK 5688 SN C A C + N + C C PG+ G SC +IDEC + +C++ F+C C S +G+ CE + V C S C +G CR C CL G+EG +C ++DDC G C G C D +N + C C +TG +C D C+ N N G C N + Sbjct: 110 SNPCENGARCTN--WNGRYNCTCPPGY--QGRSCRVDIDECRTPGLCQNGGQCVNTPGSFRCRCPSGYTGQFCEAIYVP-CAPSQCQNGGTCRQTGDLTYQCACLPGFEGPNCEINVDDCPGHKCMNGGTCVDGVNTYNCQCAPEWTGQYCTEDVDECQLQPNACHNGGTCFNTQ 279 HSP 3 Score: 93.9745 bits (232), Expect = 3.012e-18 Identity = 57/183 (31.15%), Postives = 91/183 (49.73%), Query Frame = 1 Query: 5173 SICHFNSNKCHRN-----ATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 + C N N+C + CK ++ + F C C GF GS C+ +IDEC C + ++C+D N ++C C G C+ ++ C C HG CRD +C C G+ G C I++C +PC G C D +N ++C CQQ +G+ CE ++ C + ++G C + N+ Sbjct: 448 TFCELNINECESSPCVNGGVCK--DVVNGFTCSCPAGF--TGSMCQIDIDECASTPC-KNGAKCVDRPNGYECRCAEGFEGPLCD-RNIDDCSPDPCHHGKCRDGIASFTCTCEPGYTGYRCENQINECHSNPCMHGGKCIDLVNKYLCYCQQGTSGVHCEHNYDDCASNPCDYGECRDGINR 624 HSP 4 Score: 85.5001 bits (210), Expect = 1.005e-15 Identity = 50/169 (29.59%), Postives = 85/169 (50.30%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLN 5682 + CH C + C C+PG+ G +C++ IDEC + C + C ++ + C C S +G+ CE +N C + C++G C+D +C C+ G+ G C I++C+ +PC C+D +N ++C+C +TG CE + C S N G C++ Sbjct: 805 DPCHNGGICSPTPDYESHMCQCSPGW--RGETCDDDIDECARSPC-KNGGFCTNMQGGYSCACLSGFNGQDCET-DINDCNPNPCLNGGACKDGINSFACSCIPGFTGSRCTDEINECLSNPCRNGATCKDYVNSYVCSCAPGYTGPICETNIQDCTESSCFNGGTCVD 969 HSP 5 Score: 82.8037 bits (203), Expect = 6.831e-15 Identity = 50/151 (33.11%), Postives = 71/151 (47.02%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 N N C CK + F C C PGF G+ + +EI+ECL N C + + C D VN + C C +G CE + C +S C +G C D +C C G+ G C +D+C PC +C D + + C C +TG C+ Sbjct: 881 NPNPCLNGGACKDGI--NSFACSCIPGFTGSRCT-DEINECLSNPCR-NGATCKDYVNSYVCSCAPGYTGPICET-NIQDCTESSCFNGGTCVDGVNSYTCRCRPGFTGSHCQNEVDECASRPCQNGAMCVDGVESYRCICPYGYTGAQCQ 1026 HSP 6 Score: 80.4925 bits (197), Expect = 3.263e-14 Identity = 48/167 (28.74%), Postives = 79/167 (47.31%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH--GIC---RDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 ++C TC+ + +QC C PGF G +CE +D+C + C+ + C+D VN + C C + +G+ C L+ + H G C + ++C+C++GW G C+++IDDC C C D + F C C TG+ C + N +C Sbjct: 188 SQCQNGGTCRQTG-DLTYQCACLPGF--EGPNCEINVDDCPGHKCM-NGGTCVDGVNTYNCQCAPEWTGQYCTEDVDECQLQPNACHNGGTCFNTQGGHTCVCVNGWTGESCSENIDDCATAVCFNGATCHDRVASFYCECPMGKTGLLCHLEDACVSNPCHKDAMC 350 HSP 7 Score: 79.7221 bits (195), Expect = 5.588e-14 Identity = 52/150 (34.67%), Postives = 72/150 (48.00%), Query Frame = 1 Query: 5176 ICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQ 5604 +C N + C + C + D F C C PG+ G CE +I+EC N C+ +CIDLVN + C C SG CE + C + C +G CRD C+C +G+ G CN + C +PC G C+ NGF C C + Sbjct: 525 LCDRNIDDCSPDP-CHHGKCRDGIASFTCTCEPGY--TGYRCENQINECHSNPCM-HGGKCIDLVNKYLCYCQQGTSGVHCE-HNYDDCASNPCDYGECRDGINRYDCVCKAGFTGPLCNIEVSPCASNPCRAGGTCQVTQNGFRCLCPE 669 HSP 8 Score: 76.6406 bits (187), Expect = 5.055e-13 Identity = 57/179 (31.84%), Postives = 86/179 (48.04%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKS----NELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC--EFDHFSCKNCSENFGVCLN 5682 C + ++C R + CK+ + + C C GF NG CE +I++C N CL + C D +N F C C +G C ++N CL + C +G C+D C C G+ G C +I DC C G C D +N + C C+ FTG C E D + + C +N +C++ Sbjct: 835 CDDDIDECAR-SPCKNGGFCTNMQGGYSCACLSGF--NGQDCETDINDCNPNPCL-NGGACKDGINSFACSCIPGFTGSRC-TDEINECLSNPCRNGATCKDYVNSYVCSCAPGYTGPICETNIQDCTESSCFNGGTCVDGVNSYTCRCRPGFTGSHCQNEVDECASRPC-QNGAMCVD 1007 HSP 9 Score: 76.6406 bits (187), Expect = 5.406e-13 Identity = 60/227 (26.43%), Postives = 90/227 (39.65%), Query Frame = 1 Query: 5176 ICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-------------------------------------------------ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN-CSENFGVCLNL 5685 IC N C ++ D + C C PGF GS C+ E+DEC C + + C+D V ++C+C +G C+ L V+LC +S C +G IC + S C+C G+ G C I+ C DPC+ G C L G++C C + G CE+D C++ +N G C++L Sbjct: 948 ICETNIQDCTESSCFNGGTCVDGVNSYTCRCRPGF--TGSHCQNEVDECASRPC-QNGAMCVDGVESYRCICPYGYTGAQCQNL-VDLCRRSPCQNGGRCTQTGPSFRCECPAGWAGSYCDVPRVSCEVAAARRNVRADQLCHSGGICMNAGSSHHCICRGGYTGSYCENPINQCDPDPCHNGGACHSYLGGYVCECPSGYEGKNCEYDINECQSHPCQNGGTCIDL 1170 HSP 10 Score: 71.633 bits (174), Expect = 1.654e-11 Identity = 52/164 (31.71%), Postives = 73/164 (44.51%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 I I S C A C + ++C C GF G C+ ID+C + C +C D + F C C +G CE ++N C + C+HG C D C C G G+ C + DDC +PC+ G C D +N + C C+ FTG C + C Sbjct: 490 IDIDECASTPCKNGAKCVDRP--NGYECRCAEGF--EGPLCDRNIDDCSPDPC--HHGKCRDGIASFTCTCEPGYTGYRCEN-QINECHSNPCMHGGKCIDLVNKYLCYCQQGTSGVHCEHNYDDCASNPCD-YGECRDGINRYDCVCKAGFTGPLCNIEVSPC 645 HSP 11 Score: 70.8626 bits (172), Expect = 3.323e-11 Identity = 53/170 (31.18%), Postives = 72/170 (42.35%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVG-----NGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICR------DDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN---GFICNCQQNFTGIFCEFDHFSCKNCS 5658 S+ C TC +L + C C PG +G N C + CL + + CID V ++C C +G CE +N CL C R +D C+C SG+ G C ++ C PC GVC +N G+ C C FTG CE SC+ S Sbjct: 1158 SHPCQNGGTCI--DLIGRYICSCPPGTLGVLCEINEDDCSPLSISGPPKCLNNGT-CIDKVGGYRCNCPPGYTGERCEG-DINECLSGPCHAQNTRHCVQLANDYQCVCKSGYTGRRCQSVMNTCESRPCQNGGVCSVTVNTPLGYTCRCPLGFTGPSCERPPLSCRELS 1323 HSP 12 Score: 70.4774 bits (171), Expect = 3.834e-11 Identity = 53/177 (29.94%), Postives = 77/177 (43.50%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS------CLCLSGWEGIDCNKSIDDC-IG-DPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLN 5682 C N CH TC + + C C G+ G S E ID+C C + + C D V F C C ++G C + + C+ + C D N C C G+ G C++ +D+C IG +PC G C + F C C + +TG CE D C + +N CL+ Sbjct: 262 CQLQPNACHNGGTCFNTQ--GGHTCVCVNGWTGESCS-ENIDDCATAVCF-NGATCHDRVASFYCECPMGKTGLLCHL--EDACVSNPCHKDAMCDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHFGRCVNTQGSFQCQCGRGYTGPRCETDVNECLSTPCQNDATCLD 432 HSP 13 Score: 70.0922 bits (170), Expect = 5.366e-11 Identity = 55/192 (28.65%), Postives = 78/192 (40.62%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVL---------------------------------------KVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKN 5691 C C GF G +C +IDEC CL + +C+D + + CLC +G+ CE + ++ C +S C +G C + SC CLSG+ G DC I+DC +PC G C+D +N F C+C FTG C + C N N C + N Sbjct: 746 CRCRDGF--RGPTCMIDIDECASAPCL-NGGKCMDGIAGYSCLCTLPYTGQKCETILDPCAPDPCHNGGICSPTPDYESHMCQCSPGWRGETCDDDIDECARSPCKNGGFCTNMQGGYSCACLSGFNGQDCETDINDCNPNPCLNGGACKDGINSFACSCIPGFTGSRCTDEINECLSNPCRNGATCKDYVN 934 HSP 14 Score: 59.3066 bits (142), Expect = 9.912e-8 Identity = 47/169 (27.81%), Postives = 67/169 (39.64%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSR--CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVC 5676 SN C TC+ + + F+C C G C + C C L + + C C +GR C+ ++C + C +G C D C C G+ G C ID+C PC G C D + G+ C C +TG CE C + N G+C Sbjct: 647 SNPCRAGGTCQVTQ--NGFRCLCPEGRGTRDFLCNPTQDPDKELCPPGCVHGVCRRLSDGYSCDCKVGWTGRMCDRRGSDVCTPNPCQNGGNCIDHQGVPICRCRDGFRGPTCMIDIDECASAPCLNGGKCMDGIAGYSCLCTLPYTGQKCETILDPCAPDPCHNGGIC 813 HSP 15 Score: 57.3806 bits (137), Expect = 4.067e-7 Identity = 39/128 (30.47%), Postives = 56/128 (43.75%), Query Frame = 1 Query: 5344 CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKNKNQYCLD 5712 C++ + C+C +G CE +N C C +G C C C SG+EG +C I++C PC G C D + +IC+C G+ CE + C S CLN N C+D Sbjct: 1091 CMNAGSSHHCICRGGYTGSYCEN-PINQCDPDPCHNGGACHSYLGGYVCECPSGYEGKNCEYDINECQSHPCQNGGTCIDLIGRYICSCPPGTLGVLCEINEDDCSPLSISGPPKCLN----NGTCID 1213
BLAST of Protocadherin Fat 4 vs. Ensembl Xenopus
Match: NOTCH3 (notch 3 [Source:NCBI gene;Acc:100494244]) HSP 1 Score: 100.523 bits (249), Expect = 3.469e-20 Identity = 61/177 (34.46%), Postives = 87/177 (49.15%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 +CH SN CH++A C +N +N C C PGF G G+ +++DEC N C RC++ FQC CG +G CE VN CL + C + C D + +C+C++G+ G C ID+C PC C D NG+ C C + F G C+ + C + G C Sbjct: 287 LCHLEDACVSNPCHKDAMCDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPC-EHFGRCVNTQGSFQCQCGRGYTGPRCET-DVNECLSTPCQNDATCLDRIGEFTCICMAGFTGSMCQIDIDECASTPCKNGAKCVDRPNGYECRCAEGFEGPLCDRNIDDCSPDPCHHGKC 460 HSP 2 Score: 95.5153 bits (236), Expect = 1.020e-18 Identity = 60/175 (34.29%), Postives = 83/175 (47.43%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLNLK 5688 SN C A C + N + C C PG+ G SC +IDEC + +C++ F+C C S +G+ CE + V C S C +G CR C CL G+EG +C ++DDC G C G C D +N + C C +TG +C D C+ N N G C N + Sbjct: 65 SNPCENGARCTN--WNGRYNCTCPPGY--QGRSCRVDIDECRTPGLCQNGGQCVNTPGSFRCRCPSGYTGQFCEAIYVP-CAPSQCQNGGTCRQTGDLTYQCACLPGFEGPNCEINVDDCPGHKCMNGGTCVDGVNTYNCQCAPEWTGQYCTEDVDECQLQPNACHNGGTCFNTQ 234 HSP 3 Score: 85.5001 bits (210), Expect = 1.126e-15 Identity = 51/146 (34.93%), Postives = 73/146 (50.00%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTG 5616 S C +ATC + EF C C GF GS C+ +IDEC C + ++C+D N ++C C G C+ ++ C C HG CRD +C C G+ G C I++C +PC G C D +N ++C CQQ +G Sbjct: 376 STPCQNDATCL--DRIGEFTCICMAGF--TGSMCQIDIDECASTPC-KNGAKCVDRPNGYECRCAEGFEGPLCD-RNIDDCSPDPCHHGKCRDGIASFTCTCEPGYTGYRCENQINECHSNPCMHGGKCIDLVNKYLCYCQQGTSG 515 HSP 4 Score: 81.6481 bits (200), Expect = 1.852e-14 Identity = 48/167 (28.74%), Postives = 79/167 (47.31%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH--GIC---RDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 ++C TC+ + +QC C PGF G +CE +D+C + C+ + C+D VN + C C + +G+ C L+ + H G C + ++C+C++GW G C+++IDDC C C D + F C C TG+ C + N +C Sbjct: 143 SQCQNGGTCRQTG-DLTYQCACLPGF--EGPNCEINVDDCPGHKCM-NGGTCVDGVNTYNCQCAPEWTGQYCTEDVDECQLQPNACHNGGTCFNTQGGHTCVCVNGWTGESCSENIDDCATAVCFNGATCHDRVASFYCECPMGKTGLLCHLEDACVSNPCHKDAMC 305 HSP 5 Score: 77.7962 bits (190), Expect = 2.346e-13 Identity = 58/219 (26.48%), Postives = 89/219 (40.64%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-------------------------------------------------ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN-CSENFGVCLNL 5685 ++ C TC + + C C PGF GS C+ E+DEC C + + C+D V ++C+C +G C+ L V+LC +S C +G IC + S C+C G+ G C I+ C DPC+ G C L G++C C + G CE+D C++ +N G C++L Sbjct: 831 NDSCFNGGTCVDGV--NSYTCRCRPGF--TGSHCQNEVDECASRPC-QNGAMCVDGVESYRCICPYGYTGAQCQNL-VDLCRRSPCQNGGRCTQTGPSFRCECPAGWAGSYCDVPRVSCEVAAARRNVRADQLCHSGGICMNAGSSHHCICRGGYTGSYCENPINQCDPDPCHNGGACHSYLGGYVCECPSGYEGKNCEYDINECQSHPCQNGGTCIDL 1043 HSP 6 Score: 74.3294 bits (181), Expect = 2.665e-12 Identity = 51/170 (30.00%), Postives = 82/170 (48.24%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC--EFDHFSCKNCSENFGVCLN 5682 + CH C + C C+PG+ G +C++ IDEC + C + C ++ + C C S +G+ CE +N C + C++G C+D +C C+ G+ G C D I D C G C D +N + C C+ FTG C E D + + C +N +C++ Sbjct: 720 DPCHNGGICSPTPDYESHMCQCSPGW--RGETCDDDIDECARSPC-KNGGFCTNMQGGYSCACLSGFNGQDCET-DINDCNPNPCLNGGACKDGINSFACSCIPGFTGSRCT----DEINDSCFNGGTCVDGVNSYTCRCRPGFTGSHCQNEVDECASRPC-QNGAMCVD 880 HSP 7 Score: 71.633 bits (174), Expect = 1.827e-11 Identity = 53/170 (31.18%), Postives = 72/170 (42.35%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVG-----NGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICR------DDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN---GFICNCQQNFTGIFCEFDHFSCKNCS 5658 S+ C TC +L + C C PG +G N C + CL + + CID V ++C C +G CE +N CL C R +D C+C SG+ G C ++ C PC GVC +N G+ C C FTG CE SC+ S Sbjct: 1031 SHPCQNGGTCI--DLIGRYICSCPPGTLGVLCEINEDDCSPLSISGPPKCLNNGT-CIDKVGGYRCNCPPGYTGERCEG-DINECLSGPCHAQNTRHCVQLANDYQCVCKSGYTGRRCQSVMNTCESRPCQNGGVCSVTVNTPLGYTCRCPLGFTGPSCERPPLSCRELS 1196 HSP 8 Score: 71.633 bits (174), Expect = 2.004e-11 Identity = 53/177 (29.94%), Postives = 77/177 (43.50%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS------CLCLSGWEGIDCNKSIDDC-IG-DPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLN 5682 C N CH TC + + C C G+ G S E ID+C C + + C D V F C C ++G C + + C+ + C D N C C G+ G C++ +D+C IG +PC G C + F C C + +TG CE D C + +N CL+ Sbjct: 217 CQLQPNACHNGGTCFNTQ--GGHTCVCVNGWTGESCS-ENIDDCATAVCF-NGATCHDRVASFYCECPMGKTGLLCHL--EDACVSNPCHKDAMCDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHFGRCVNTQGSFQCQCGRGYTGPRCETDVNECLSTPCQNDATCLD 387 HSP 9 Score: 67.781 bits (164), Expect = 2.454e-10 Identity = 46/156 (29.49%), Postives = 71/156 (45.51%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKS----NELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKS-DCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 C + ++C R + CK+ + + C C GF NG CE +I++C N CL + C D +N F C C +G C + C CV G+ + +C C G+ G C +D+C PC +C D + + C C +TG C+ Sbjct: 750 CDDDIDECAR-SPCKNGGFCTNMQGGYSCACLSGF--NGQDCETDINDCNPNPCL-NGGACKDGINSFACSCIPGFTGSRCTDEINDSCFNGGTCVDGV--NSYTCRCRPGFTGSHCQNEVDECASRPCQNGAMCVDGVESYRCICPYGYTGAQCQ 899 HSP 10 Score: 66.2402 bits (160), Expect = 7.830e-10 Identity = 51/168 (30.36%), Postives = 70/168 (41.67%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSG------------------RTCEVLKVNLCLKSDCVHG-ICR-----DDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVC 5676 C C GF G +C +IDEC CL + +C+D + + CLC +G + CE + ++ C C +G IC + + C C GW G C+ ID+C PC G C + G+ C C F G CE D C N N G C Sbjct: 643 CRCRDGF--RGPTCMIDIDECASAPCL-NGGKCMDGIAGYSCLCTLPYTGMWWKRKQQIADFIFQPPGQKCETI-LDPCAPDPCHNGGICSPTPDYESHMCQCSPGWRGETCDDDIDECARSPCKNGGFCTNMQGGYSCACLSGFNGQDCETDINDCNPNPCLNGGAC 806 HSP 11 Score: 57.7658 bits (138), Expect = 2.630e-7 Identity = 39/128 (30.47%), Postives = 56/128 (43.75%), Query Frame = 1 Query: 5344 CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKNKNQYCLD 5712 C++ + C+C +G CE +N C C +G C C C SG+EG +C I++C PC G C D + +IC+C G+ CE + C S CLN N C+D Sbjct: 964 CMNAGSSHHCICRGGYTGSYCEN-PINQCDPDPCHNGGACHSYLGGYVCECPSGYEGKNCEYDINECQSHPCQNGGTCIDLIGRYICSCPPGTLGVLCEINEDDCSPLSISGPPKCLN----NGTCID 1086 HSP 12 Score: 57.7658 bits (138), Expect = 2.789e-7 Identity = 44/147 (29.93%), Postives = 62/147 (42.18%), Query Frame = 1 Query: 5176 ICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQ 5604 +C N + C + C + D F C C PG+ G CE +I+EC N C+ +CIDLVN + C C SG+ C + + + NSC CN + C +PC G C+ NGF C C + Sbjct: 442 LCDRNIDDCSPDP-CHHGKCRDGIASFTCTCEPGY--TGYRCENQINECHSNPCM-HGGKCIDLVNKYLCYCQQGTSGK---------CNNGGSIEDLTQK-NSCPL--------CNIEVSPCASNPCRAGGTCQVTQNGFRCLCPE 566
BLAST of Protocadherin Fat 4 vs. Ensembl Xenopus
Match: notch1 (notch 1 receptor [Source:NCBI gene;Acc:100037842]) HSP 1 Score: 99.3673 bits (246), Expect = 6.696e-20 Identity = 61/175 (34.86%), Postives = 94/175 (53.71%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 + C +N C C +N L FQC C G+ G CE +++ECL N C D++ C+D + +FQC+C +GR CE +N C+ C +G C+D + CLC G+ G C+ I++C+ PC G C D NG+IC C + TG+ CE + C + ++G C++ Sbjct: 412 VDECSLGANPCEHGGRC-TNTLG-SFQCNCPQGYAG--PRCEIDVNECLSNPCQNDAT-CLDQIGEFQCICMPGFTGRHCE-QDINECIPDPCHYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSQPCQNGGQCTDRENGYICTCPKGTTGVNCETNLDDCASNPCDYGKCID 580 HSP 2 Score: 82.8037 bits (203), Expect = 7.638e-15 Identity = 53/156 (33.97%), Postives = 76/156 (48.72%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCE------VLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 N + C TC+ + + ++C C PGF +G +CEE ID+C N C + C+D VN + C C D +G+ C L N C H N C+C++GW G DC+++IDDC C+ C D + F C C TG+ C D Sbjct: 222 NPSPCLNGGTCRQTD-DTSYECTCLPGF--SGQNCEENIDDCPSNNCR-NGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYN-CVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFFCECPHGRTGLLCHLD 372 HSP 3 Score: 78.5666 bits (192), Expect = 1.601e-13 Identity = 50/152 (32.89%), Postives = 76/152 (50.00%), Query Frame = 1 Query: 5239 DEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLN 5682 D ++C C PG+ G + IDEC N C + C D +N F C+C C + +VN C + C+HG C D C C +GW G +C+ + ++C +PC G C+D +IC C+ F+G C+ + C N N G C++ Sbjct: 583 DGYECTCEPGYTGKMCN-INIDECASNPCR-NGGTCKDKINGFTCVCPDGYHDHMC-LSEVNECNSNPCIHGTCHDGINGYKCDCDAGWSGSNCDVNNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCID 731 HSP 4 Score: 73.559 bits (179), Expect = 4.467e-12 Identity = 52/150 (34.67%), Postives = 71/150 (47.33%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI----CRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 C A C++ N ++C C PG+ G CE +ID+C N C S C D +N F C C + G CE +N C + C +G C + +C C G+ GI C + DC C G C D +N F C C FTG +C+ D Sbjct: 801 CRNGAMCQN--TNGSYKCNCKPGYAGR--HCETDIDDCQPNPCHNGGS-CSDGINMFFCNCPAGFRGPKCEE-DINECASNPCKNGANCTDCVNSYTCTCQPGFSGIHCENNTPDCTESSCFNGGTCIDGINTFSCQCPPGFTGNYCQHD 944 HSP 5 Score: 73.1738 bits (178), Expect = 5.748e-12 Identity = 52/150 (34.67%), Postives = 79/150 (52.67%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 SN C TCK +++N F C C G+ + E++EC N C+ C D +N ++C C + SG C+V N C + C++G C+D C C +G+ G +C +I++C +PC RG C D + G+ CNC +TG CE Sbjct: 607 SNPCRNGGTCK-DKING-FTCVCPDGYHDH-MCLSEVNECNSNPCI--HGTCHDGINGYKCDCDAGWSGSNCDV-NNNECESNPCMNGGTCKDMTGAYICTCRAGFSGPNCQTNINECASNPCLNRGTCIDDVAGYKCNCMLPYTGAICE 750 HSP 6 Score: 72.0182 bits (175), Expect = 1.277e-11 Identity = 61/207 (29.47%), Postives = 91/207 (43.96%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVG---------------NGSSC---------------------EEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICR--DDNS--CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLN 5682 N C TC+ +++C C PG+ G NG C ++I+EC N C + +C++ ++C C + +GR CE V C S C++ G CR DD S C CL G+ G +C ++IDDC + C G C D +N + C C ++TG +C D C+ N +N G C N Sbjct: 109 NPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQQADPCASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCR-NGGQCLNEFGSYRCNCQNRFTGRNCEEPYV-PCNPSPCLNGGTCRQTDDTSYECTCLPGFSGQNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHN 313 HSP 7 Score: 70.8626 bits (172), Expect = 3.036e-11 Identity = 44/130 (33.85%), Postives = 62/130 (47.69%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC 5625 F C C PG+ G +I+ECL C + +C D N + C C +G CE ++ C + C +G C D C C G+ G CN +ID+C +PC G C+D +NGF C C + C Sbjct: 510 FTCLCRPGYTGRLCD-NDINECLSQPCQ-NGGQCTDRENGYICTCPKGTTGVNCET-NLDDCASNPCDYGKCIDKIDGYECTCEPGYTGKMCNINIDECASNPCRNGGTCKDKINGFTCVCPDGYHDHMC 636 HSP 8 Score: 68.1662 bits (165), Expect = 1.865e-10 Identity = 50/166 (30.12%), Postives = 77/166 (46.39%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 SN C A C + + + C C PGF +G CE +C + C + CID +N F C C +G C+ +N C C++G C+D C C G+ G++C + C PC G C N + C C+ +TG++C+ SC+ ++ GV Sbjct: 874 SNPCKNGANC--TDCVNSYTCTCQPGF--SGIHCENNTPDCTESSCF-NGGTCIDGINTFSCQCPPGFTGNYCQ-HDINECDSKPCLNGGTCQDSYGAYKCTCPQGYTGLNCQNLVRWCDSSPCKNGGKCWQTNNFYRCECKSGWTGVYCDVPSVSCEVAAKQQGV 1033 HSP 9 Score: 67.781 bits (164), Expect = 2.654e-10 Identity = 57/192 (29.69%), Postives = 79/192 (41.15%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEV---------------------------------------LKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 SN C TCK ++ + C C GF +G +C+ I+EC N CL + CID V ++C C +G CE + +N C+ C +G +C++ N C C G+ G C IDDC +PC+ G C D +N F CNC F G CE D Sbjct: 682 SNPCMNGGTCK--DMTGAYICTCRAGF--SGPNCQTNINECASNPCL-NRGTCIDDVAGYKCNCMLPYTGAICEAVLAPCSGSPCKNGGRCKESEDYETFSCECPPGWQGQTCEIDMNECVNRPCRNGAMCQNTNGSYKCNCKPGYAGRHCETDIDDCQPNPCHNGGSCSDGINMFFCNCPAGFRGPKCEED 868 HSP 10 Score: 66.6254 bits (161), Expect = 5.897e-10 Identity = 57/183 (31.15%), Postives = 85/183 (46.45%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEV-------LKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGV--CEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKNKNQ 5700 N C ATC + + C C G+ G S EEI+ECL + C + CIDL+N ++C C G CE+ ++ L+ C + G C D +C+C G+ G C +++C+ +PC+ RG C +N + C C+Q FTG C+ CK N G C N + Sbjct: 1075 NPCQNGATC--TDYLGGYSCECVAGYHGVNCS-EEINECLSHPCH-NGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGGYNCICPPGFVGERCEGDVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFTGRRCDSVVDGCKGLPCRNGGTCAVASNTER 1253 HSP 11 Score: 62.7734 bits (151), Expect = 8.463e-9 Identity = 34/105 (32.38%), Postives = 59/105 (56.19%), Query Frame = 1 Query: 5332 DSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 +S C+D N C C + +G CE +V+ C + C +G C D SC C++G+ G++C++ I++C+ PC+ G C D +N + C+C + G+ CE + Sbjct: 1041 NSGMCVDTGNTHFCRCQAGYTGSYCEE-QVDECSPNPCQNGATCTDYLGGYSCECVAGYHGVNCSEEINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEIN 1144 HSP 12 Score: 60.4622 bits (145), Expect = 4.248e-8 Identity = 45/138 (32.61%), Postives = 66/138 (47.83%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSR-CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS------CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEF 5631 + C C PGFVG CE +++ECL N C ++ CI LVND++C C +GR C+ + V+ C C +G C ++ C C G++G C C C G C L C C + +TG C++ Sbjct: 1174 YNCICPPGFVG--ERCEGDVNECLSNPCDPRGTQNCIQLVNDYRCECRQGFTGRRCDSV-VDGCKGLPCRNGGTCAVASNTERGFICKCPPGFDGATCEYDARTCGNLRCQNGGTCISVLKSSKCVCSEGYTGATCQY 1308 HSP 13 Score: 60.077 bits (144), Expect = 6.413e-8 Identity = 50/170 (29.41%), Postives = 76/170 (44.71%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELND--EFQCFCNPGFVGNGSSCEEIDECLFNFCL-GDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-IC---RDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 N+C TC+ L + +F C C GF + C+ N C G + + V+D++C C +G +C+ + + C + C +G C C C SG+ G C + I++C +PC G C + + CNCQ FTG CE + C N CLN Sbjct: 66 NQCMNFGTCEPVLLGNAIDFTCHCPVGFTDKVCLTPVDNACVNNPCRNGGTCELLSSVSDYRCRCPPGWTGDSCQ--QADPCASNPCANGGKCLPFETQYICKCPSGFHGATCKQDINECSQNPCRNGGQCLNEFGSYRCNCQNRFTGRNCEEPYVPC-----NPSPCLN 228 HSP 14 Score: 55.0694 bits (131), Expect = 2.044e-6 Identity = 46/141 (32.62%), Postives = 63/141 (44.68%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDC--------IGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 C C G+ G S CEE +DEC N C + + C D + + C C + G C ++N CL C +G C D C C G +G+ C ++DDC + C G C D + G+ C C F G CE D Sbjct: 1054 CRCQAGYTG--SYCEEQVDECSPNPCQ-NGATCTDYLGGYSCECVAGYHGVNCSE-EINECLSHPCHNGGTCIDLINTYKCSCPRGTQGVHCEINVDDCTPFYDSVSLEPKCFNNGKCIDRVGGYNCICPPGFVGERCEGD 1190
BLAST of Protocadherin Fat 4 vs. Ensembl Mouse
Match: Notch3 (notch 3 [Source:MGI Symbol;Acc:MGI:99460]) HSP 1 Score: 107.071 bits (266), Expect = 2.699e-22 Identity = 63/169 (37.28%), Postives = 87/169 (51.48%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFC--LGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 +CH + SN CH +A C +N ++ C C PGF G G+ +++DEC N C LG RC++ F C CG +G CE VN CL C + C D +C+C++G+ G C ID+C PC GVC+D +NGF C C F+G C+ D C Sbjct: 349 LCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTG-GACDQDVDECSIGANPCEHLG---RCVNTQGSFLCQCGRGYTGPRCET-DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVDEC 512 HSP 2 Score: 92.0485 bits (227), Expect = 8.260e-18 Identity = 57/179 (31.84%), Postives = 84/179 (46.93%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 + I S+ C CK + F C C GF +GS C+ ++DEC C + ++C+D + ++C C G CE V+ C C HG C D SC C G+ GI C +D+C PC G C D ++ ++C C TG+ CE + C + FGVC + N+ Sbjct: 469 VDIDECQSSPCVNGGVCKDRV--NGFSCTCPSGF--SGSMCQLDVDECASTPCR-NGAKCVDQPDGYECRCAEGFEGTLCE-RNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFGVCRDGINR 641 HSP 3 Score: 88.5817 bits (218), Expect = 9.955e-17 Identity = 60/174 (34.48%), Postives = 78/174 (44.83%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS----CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLNL 5685 S C A C + F C C PG+ G SC+ +IDEC C++ F+C C +G CE V C S C +G CR + C CL G+EG +C ++DDC G C G C D +N + C C +TG FC D C+ N N G C NL Sbjct: 126 SRPCVHGAPCSVGP-DGRFACACPPGY--QGQSCQSDIDECRSGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCEN-PVVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNL 295 HSP 4 Score: 84.7297 bits (208), Expect = 1.419e-15 Identity = 56/175 (32.00%), Postives = 79/175 (45.14%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 ++C N + C + C D F C C PG+ G CE ++DEC C +C+DLV+ + C C +G CEV ++ C + C G+CRD C+C G+ G CN I++C PC G C D NGF C C C + C + + GVC Sbjct: 541 TLCERNVDDCSPDP-CHHGRCVDGIASFSCACAPGY--TGIRCESQVDECRSQPCRY-GGKCLDLVDKYLCRCPPGTTGVNCEV-NIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCSHGVC 710 HSP 5 Score: 83.1889 bits (204), Expect = 4.094e-15 Identity = 52/166 (31.33%), Postives = 80/166 (48.19%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLC-LKSDCVH--GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C TC+ + + + C C PGF G +CE +D+C + CL + C+D VN + C C + +G+ C V+ C L+ + H G C + +SC+C++GW G C+++IDDC C C D + F C C TG+ C D N +C Sbjct: 207 CRNGGTCRQSS-DVTYDCACLPGF--EGQNCEVNVDDCPGHRCL-NGGTCVDGVNTYNCQCPPEWTGQFC-TEDVDECQLQPNACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAIC 367 HSP 6 Score: 78.9518 bits (193), Expect = 7.260e-14 Identity = 57/176 (32.39%), Postives = 73/176 (41.48%), Query Frame = 1 Query: 5179 CHFNSNKCHRN----ATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNL-CLKSDCVHGICRDDNS---CLCLSGWEGIDCNKSI--DDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C N + C N C+ + + C C PGF G + E I+EC + C G+ C+D N F CLC C L N C C HG+C D C+C GW G C++S+ D C PC G C GF C C F G CE + E+ G C Sbjct: 618 CEVNIDDCASNPCTFGVCRDGI--NRYDCVCQPGFTGPLCNVE-INECASSPC-GEGGSCVDGENGFHCLCPPGSLPPLC--LPANHPCAHKPCSHGVCHDAPGGFRCVCEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFRCTCAPGFQGHQCEVLSPCTPSLCEHGGHC 787 HSP 7 Score: 75.485 bits (184), Expect = 1.017e-12 Identity = 50/151 (33.11%), Postives = 65/151 (43.05%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 + N C +C+ F C C GF G + ++DECL + C C D V F C C G CE+ + C S C +G C D SCLC G+ G C D C PC G+C GF C C++ FTG C+ Sbjct: 855 DPNPCLHGGSCQDGV--GSFSCSCLDGFAGPRCA-RDVDECLSSPC--GPGTCTDHVASFTCACPPGYGGFHCEI-DLPDCSPSSCFNGGTCVDGVSSFSCLCRPGYTGTHCQYEADPCFSRPCLHGGICNPTHPGFECTCREGFTGSQCQ 999 HSP 8 Score: 70.0922 bits (170), Expect = 3.622e-11 Identity = 50/168 (29.76%), Postives = 68/168 (40.48%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 S C TC S+ + F+C C PGF G CE + C + C D C C G C+ S C HG C + + C+C G+ G C++ IDDC +PC G C+D + F C+C F G C D C + G C + Sbjct: 741 SQPCQAGGTCTSDGIG--FRCTCAPGF--QGHQCEVLSPCTPSLCEHGGHCESDPDRLTVCSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGNFRCICHRGYTGPFCDQDIDDCDPNPCLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLSSPCGPGTCTD 904 HSP 9 Score: 67.0106 bits (162), Expect = 3.116e-10 Identity = 42/145 (28.97%), Postives = 62/145 (42.76%), Query Frame = 1 Query: 5251 CFCNPGFVGN---------GSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C C PG+ G + ++ L C + +CID C+C R+G CE +V+ C C HG CR C C +G+ G C +ID+C PC G C D + ++C+C G+ CE + C Sbjct: 1023 CICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQLC-QEGGKCIDKGRSHYCVCPEGRTGSHCE-HEVDPCTAQPCQHGGTCRGYMGGYVCECPAGYAGDSCEDNIDECASQPCQNGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1165 HSP 10 Score: 63.1586 bits (152), Expect = 5.118e-9 Identity = 49/174 (28.16%), Postives = 68/174 (39.08%), Query Frame = 1 Query: 5185 FNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGD---SSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG----ICRDDN-SCLCLSGWEGIDCNKSIDDC-IGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVC 5676 + + C C + + E C C PG+V G C+ D C C G S + F C C G C + + C+ CVHG + D +C C G++G C ID+C G C G C + F C C +TG+ CE C + N G C Sbjct: 44 LDGSPCANGGRCTHQQPSLEAACLCLPGWV--GERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCLRGFQGPDCS--QPDPCVSRPCVHGAPCSVGPDGRFACACPPGYQGQSCQSDIDECRSGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCENPVVPCAPSPCRNGGTC 213 HSP 11 Score: 58.151 bits (139), Expect = 1.732e-7 Identity = 50/184 (27.17%), Postives = 69/184 (37.50%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGN-----------GSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD-------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN-----GFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 S C +C +L + C C PG +G G S + +CL N C+DLV F+C C +G CE +N C C RD C+C G+ G C ++ C PC G C +L F C+C F G+ CE SC+ G+ Sbjct: 1129 SQPCQNGGSCI--DLVARYLCSCPPGTLGVLCEINEDDCDLGPSLDSGVQCLHN------GTCVDLVGGFRCNCPPGYTGLHCEA-DINECRPGACHAAHTRDCLQDPGGHFRCVCHPGFTGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTCHCVPPFWGLRCERVARSCRELQCPVGI 1303 HSP 12 Score: 57.3806 bits (137), Expect = 2.726e-7 Identity = 46/145 (31.72%), Postives = 63/145 (43.45%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDP-------CNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK 5649 C C G GS CE E+D C C + C + + C C + +G +CE ++ C C +G C D + C C G G+ C + DDC P C G C D + GF CNC +TG+ CE D C+ Sbjct: 1071 CVCPEG--RTGSHCEHEVDPCTAQPCQHGGT-CRGYMGGYVCECPAGYAGDSCED-NIDECASQPCQNGGSCIDLVARYLCSCPPGTLGVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECR 1211
BLAST of Protocadherin Fat 4 vs. Ensembl Mouse
Match: Notch4 (notch 4 [Source:MGI Symbol;Acc:MGI:107471]) HSP 1 Score: 100.908 bits (250), Expect = 1.503e-20 Identity = 61/151 (40.40%), Postives = 78/151 (51.66%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 S CH +TC +L F C C PG G CE E++EC N CL ++ C DL+N FQCLC +G CE ++ C + C +G CRD C CL G+EG C K +D+C+ DPC C D F C C+ FTG CE Sbjct: 478 SQPCHPGSTCL--DLLATFHCLCPPGL--EGRLCEVEVNECTSNPCLNQAA-CHDLLNGFQCLCLPGFTGARCEK-DMDECSSTPCANGGRCRDQPGAFYCECLPGFEGPHCEKEVDECLSDPCPVGASCLDLPGAFFCLCRPGFTGQLCE 622 HSP 2 Score: 95.1301 bits (235), Expect = 8.544e-19 Identity = 63/173 (36.42%), Postives = 80/173 (46.24%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSC-EEIDECLF-----NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN 5652 +CH S CH NA C +N L C C PG+ +GS+C +++DEC + C S CI+ F CLC +G CE N CL C G C D CLC G EG C +++C +PC + C D LNGF C C FTG CE D C + Sbjct: 386 LCHLEDMCLSQPCHVNAQCSTNPLTGSTLCICQPGY--SGSTCHQDLDECQMAQQGPSPCEHGGS-CINTPGSFNCLCLPGYTGSRCEA-DHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGRLCEVEVNECTSNPCLNQAACHDLLNGFQCLCLPGFTGARCEKDMDECSS 554 HSP 3 Score: 77.0258 bits (188), Expect = 3.452e-13 Identity = 60/202 (29.70%), Postives = 83/202 (41.09%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDE---FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEV--LKVNL---------------CLKSD-------------CVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C + ++C D+ F C C PGF G CE E+DECL + C +S C+DL F CLC +G+ CEV N+ CL D C HG C+ + C+C GW G +C + CI PC G C +G+ C C + G+ C + +C + G CLN Sbjct: 545 CEKDMDECSSTPCANGGRCRDQPGAFYCECLPGF--EGPHCEKEVDECLSDPCPVGAS-CLDLPGAFFCLCRPGFTGQLCEVPLCTPNMCQPGQQCQGQEHRAPCLCPDGSPGCVPAEDNCPCHHGHCQR-SLCVCDEGWTGPECETELGGCISTPCAHGGTCHPQPSGYNCTCPAGYMGLTCSEEVTACHS-----GPCLN 737 HSP 4 Score: 71.633 bits (174), Expect = 1.275e-11 Identity = 54/181 (29.83%), Postives = 82/181 (45.30%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNF--CLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG----ICRDDNS----CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-----NCSENFGVCLN 5682 ++N C C + + QC C PGF G +CE +I+EC C +S C + + +QCLC + G C+ L+ C C++G + + +S CLC G+ G+DC + DDC+ C C D L+ + C C + + G C D C+ C N G C N Sbjct: 158 SANPCANGGVCLATY--PQIQCRCPPGF--EGHTCERDINECFLEPGPCPQGTS-CHNTLGSYQCLCPVGQEGPQCK-LRKGACPPGSCLNGGTCQLVPEGHSTFHLCLCPPGFTGLDCEMNPDDCVRHQCQNGATCLDGLDTYTCLCPKTWKGWDCSEDIDECEARGPPRC-RNGGTCQN 331 HSP 5 Score: 68.9366 bits (167), Expect = 9.600e-11 Identity = 56/200 (28.00%), Postives = 73/200 (36.50%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVL----------------------------------------------KVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C ATC+ +C C+PG+ GSSC+ ID C C ++RC+ FQCLC +G C+ VN C + C HG C S C C G+EG +C+K +D C PC+ G C GF C C F G+ CE D C Sbjct: 812 CRNKATCQDTPRGA--RCLCSPGY--TGSSCQTLIDLCARKPC-PHTARCLQSGPSFQCLCLQGWTGALCDFPLSCQKAAMSQGIEISGLCQNGGLCIDTGSSYFCRCPPGFQGKLCQDNVNPCEPNPCHHGSTCVPQPSGYVCQCAPGYEGQNCSKVLDACQSQPCHNHGTCTSRPGGFHCACPPGFVGLRCEGDVDEC 1006 HSP 6 Score: 67.3958 bits (163), Expect = 2.568e-10 Identity = 50/173 (28.90%), Postives = 72/173 (41.62%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 ++ CH S C +C + + C C P G C+ +D C+ CL + C++ F CLC + G CE C S C + C+D CLC G+ G C ID C PC C + F C C Q +TG C+F SC+ + + G+ Sbjct: 727 VTACH--SGPCLNGGSCSIRP--EGYSCTCLPSHTGR--HCQTAVDHCVSASCL-NGGTCVNKPGTFFCLCATGFQGLHCEEKTNPSCADSPCRNKATCQDTPRGARCLCSPGYTGSSCQTLIDLCARKPCPHTARCLQSGPSFQCLCLQGWTGALCDFP-LSCQKAAMSQGI 891 HSP 7 Score: 64.3142 bits (155), Expect = 2.103e-9 Identity = 40/135 (29.63%), Postives = 63/135 (46.67%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTC--EVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 C C PGF G CE D+C+ + C + + C+D ++ + CLC G C ++ + C +G C++ C+C+SGW G C +++DDC C C D + F C C TG+ C + Sbjct: 259 CLCPPGF--TGLDCEMNPDDCVRHQC-QNGATCLDGLDTYTCLCPKTWKGWDCSEDIDECEARGPPRCRNGGTCQNTAGSFHCVCVSGWGGAGCEENLDDCAAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE 390 HSP 8 Score: 63.1586 bits (152), Expect = 5.130e-9 Identity = 53/174 (30.46%), Postives = 68/174 (39.08%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-------VHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN---GFICNCQQNFTGIFCEFDHFSC--KNCSENFGVCL 5679 N CH +TC + C C PG+ G S + +D C C + C F C C G CE V+ CL C H + + C CL G G C +D C PC+ G CE GF C+C + F G C SC +C N G+CL Sbjct: 933 NPCHHGSTCVPQP--SGYVCQCAPGYEGQNCS-KVLDACQSQPC-HNHGTCTSRPGGFHCACPPGFVGLRCEG-DVDECLDRPCHPSGTAACHSLA-NAFYCQCLPGHTGQRCEVEMDLCQSQPCSNGGSCEITTGPPPGFTCHCPKGFEGPTCSHKALSCGIHHC-HNGGLCL 1099 HSP 9 Score: 58.5362 bits (140), Expect = 1.105e-7 Identity = 49/175 (28.00%), Postives = 70/175 (40.00%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEID--ECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDN---SCLCLSGWEGIDCNKSIDDC----------IGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK 5649 ++ H S C TC + F C C GF G CEE C + C ++ C D +CLC +G +C+ L ++LC + C H C CLCL GW G C+ + C I C G+C D + + C C F G C+ + C+ Sbjct: 764 AVDHCVSASCLNGGTCVNKP--GTFFCLCATGF--QGLHCEEKTNPSCADSPCRNKAT-CQDTPRGARCLCSPGYTGSSCQTL-IDLCARKPCPHTARCLQSGPSFQCLCLQGWTGALCDFPLS-CQKAAMSQGIEISGLCQNGGLCIDTGSSYFCRCPPGFQGKLCQDNVNPCE 931 HSP 10 Score: 56.6102 bits (135), Expect = 4.733e-7 Identity = 38/131 (29.01%), Postives = 54/131 (41.22%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG----ICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 C C+ G+ G CE E+ C+ C C + + C C + G TC +V C C++G I + SC CL G C ++D C+ C G C + F C C F G+ CE Sbjct: 674 CVCDEGW--TGPECETELGGCISTPC-AHGGTCHPQPSGYNCTCPAGYMGLTCSE-EVTACHSGPCLNGGSCSIRPEGYSCTCLPSHTGRHCQTAVDHCVSASCLNGGTCVNKPGTFFCLCATGFQGLHCE 800 HSP 11 Score: 52.7582 bits (125), Expect = 6.471e-6 Identity = 45/151 (29.80%), Postives = 54/151 (35.76%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVN--------------DFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS----CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C C PGF+G +C+ D C + C L+ F C C S +G C+ LC S C +G C S C C GW G C D C +PC GVC C C F G CE D C Sbjct: 48 CQCAPGFLG--ETCQFPDPCRDTQLCKNGGSCQALLPTPPSSRSPTSPLTPHFSCTCPSGFTGDRCQTHLEELCPPSFCSNGGHCYVQASGRPQCSCEPGWTGEQCQLR-DFCSANPCANGGVCLATYPQIQCRCPPGFEGHTCERDINEC 195
BLAST of Protocadherin Fat 4 vs. Ensembl Mouse
Match: Svep1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:MGI Symbol;Acc:MGI:1928849]) HSP 1 Score: 95.9005 bits (237), Expect = 5.688e-19 Identity = 56/156 (35.90%), Postives = 77/156 (49.36%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 N CH + TC+ +L + C C PG+ G CE +IDEC CL + C D V F C C SG+ CE +N C+ S C++ G C D C C+ G+ G+ C +++C PC VC+D + GF C C F G CE + C Sbjct: 1199 NPCHNSGTCQ--QLGRGYVCLCPPGY--TGLKCETDIDECSSLPCL-NGGICRDQVGGFTCECSLGYSGQICEE-NINECISSPCLNKGTCTDGLASYRCTCVKGYMGVHCETDVNECQSSPCLNNAVCKDQVGGFSCKCPPGFLGTRCEKNVDEC 1348 HSP 2 Score: 82.8037 bits (203), Expect = 5.555e-15 Identity = 54/167 (32.34%), Postives = 81/167 (48.50%), Query Frame = 1 Query: 5176 ICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN 5652 IC N N+C + D ++C C G++G CE +++EC + CL +++ C D V F C C G CE V+ CL C +G C+D + C C +G+ G C +I++C +PC + C D LN + C CQ F+G CE + S N Sbjct: 1264 ICEENINECISSPCLNKGTCTDGLASYRCTCVKGYMG--VHCETDVNECQSSPCL-NNAVCKDQVGGFSCKCPPGFLGTRCEK-NVDECLSQPCQNGATCKDGANSFRCQCPAGFTGTHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGHRCETEQPSGFN 1426 HSP 3 Score: 77.411 bits (189), Expect = 2.409e-13 Identity = 48/146 (32.88%), Postives = 69/146 (47.26%), Query Frame = 1 Query: 5287 SCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQYCLD 5712 S + EC N C +S C L + CLC +G CE ++ C C++ GICRD +C C G+ G C ++I++CI PC +G C D L + C C + + G+ CE D C++ CLN N C D Sbjct: 1189 SSQVFHECFLNPC-HNSGTCQQLGRGYVCLCPPGYTGLKCET-DIDECSSLPCLNGGICRDQVGGFTCECSLGYSGQICEENINECISSPCLNKGTCTDGLASYRCTCVKGYMGVHCETDVNECQSSP-----CLN----NAVCKD 1323
BLAST of Protocadherin Fat 4 vs. Ensembl Mouse
Match: Fat4 (FAT atypical cadherin 4 [Source:MGI Symbol;Acc:MGI:3045256]) HSP 1 Score: 94.3597 bits (233), Expect = 1.976e-18 Identity = 52/150 (34.67%), Postives = 76/150 (50.67%), Query Frame = 1 Query: 5224 SNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS 5658 +NE QC C PG+ G S CE +IDECL C + C +LV F C C +GR CE +N CL S C HG +C++ +C+C +G+ G C S++ C +PC G C+ + + C+C G CE + + + S Sbjct: 3841 ANEPLQPSQCKCVPGYAG--SWCEVDIDECLPAPCH-NGGTCHNLVGGFSCSCPEGFTGRACE-RDINECLPSPCKHGAVCQNFPGGFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVESYYCHCPFGVFGKHCELNSYGFEELS 3986 HSP 2 Score: 81.6481 bits (200), Expect = 1.337e-14 Identity = 140/555 (25.23%), Postives = 240/555 (43.24%), Query Frame = 1 Query: 736 EIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINE----LYSFQI----LILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYK---DQILIFNKTYFIQLIDVNE-APQGLT-LYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFN-------EIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDV--NEKDFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFH-IMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMK-----NFTAIMKIFIFVENVNE------PPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILN 2250 ++ I+ EL + E Q + +DR LS V + +L D N N + EE + +G++SA+D+D Y+F++ LH + EI ++ + +ES + + V F V A Q L T + + D+N+ AP+ L Y +TV+E + + + + S D +++ S LI ++ F I F ++ +LDYE T AY+L I+ D G + + + ++I D N+ + S + EN IG L++ + A D+D N+ L YT+ N F I N +G++F D E + Y++ IT D G P + + + I++ + N+NP ++F I+EN L + ++T +PD D IN Q+ S ++Q+ N F D + + +D E N FE+ ++ ND A+ + I V ++N+ LA D S I +T + DPD+ N ++Y ILN Sbjct: 1051 QLYIKSEL--DRELQDRYVLLVVASDRAVEPLSATVNVTVLLEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYAFEVTQPNFELHAVTGEITSTHK-FDRESL-MRRRGTAVFSFTVTAMDRGLPQPLKDQATVHVYMKDINDNAPKFLKDFYQATVSETATNLTQVLRVSASD------VDEGSNGLIHYSILKGNEERQFAIDSFSGQVTLVGKLDYEATSAYSLLIQAVDSGAIPLNSTCTLSIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGVNADLHYTITGSNNHGTFSISPN---TGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIQVRDFNDNPPSFPPG------DIFKSIVENIPLGTSVISVTAHDPDAD--INGQL----SYAIIQQMPR-GNHFSIDEVKGTIYTSAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAMIGSVLT----------TIMAADPDEGANGEVEYEILN 1569 HSP 3 Score: 80.8777 bits (198), Expect = 2.509e-14 Identity = 287/1402 (20.47%), Postives = 540/1402 (38.52%), Query Frame = 1 Query: 373 PFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVT--DINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVK--IIILNVDENPTDLKLN--DSTSNKVLIEENSS-NYSLGELSAIDED---INELYSFQILI----LHTDSVEIKHKNELWIKESAELNYE--SSY---VNYFVVGAYKDQILIFNKTYFIQLI----DVNEAPQGL--TLYPSTVTENIPSGSVIGKFSILD--SNLNSTIEKCSLQLITFNEI--FLISQFQ--LELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE------RPENLSLSNNQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKD---FYIE--NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQI---ISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFV---ENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKV-------NVFDEDNLSTYNQIECSIIKPLK-----WFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATF-SFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQ----IHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVND-GPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGIS---------------NSSIYIAKRLDYETFTKMETIVVCFDQSG--LNVSSVFQIDIEDVNEPPENVKISNDQWN--EKSEIGLLIANLSANDPEG---SQVQFVLNSCKNVECPFYILQNS-SIFLNKSLQVLTENDQLEFEVTVSD----ILNTNVSLSLEVTIFRENLAQISME--FKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEI-------FSDGNFFIIVDFK--VLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVT 4251 P A +L +K LD E ++++++E D +++VT DIN+ P ++ ++ + + E++ G+ + + D D + D L I ++ L F RQ L Q TDR SL+ + I +L+V++N +K +TS ++EN+ + L+ D D N S QIL H + K N IK ++ L+ E SY V+ + ++ L+ D+N+ P +Y ++E +P GS + S D S LN+ + +++ N + F IS+ + LD E L I D G V+ ++++ + D N+ +PE +S + EN P G + ++ A D D N T+ ++L E D F ++ + +L + + D E + Y ++I D G P + + ++ +L+ N+N + QY HI EN T++ +PD + D SRF + KS + ++ LD E+ +++ + D N + + + V + + PP S + N+ GY + + T D N I Y I +++ F+ L + D E +K++ G ++ D V I+++D ND P F++ I V ++F + + ++ LK F+I QN I + +EI + G ++ S+ T + + D+N+ P F ++ V N ++ S + +I+ + I +N I D + LD E ++ +++ D+ + ++N+ V + DVN+ S E+ + A D D+ ++F++ + N E+ H++ + + D SL + F V + R QP L Q+ ++ + ++ND P + + T + + N+ VL + + + GSN S + + + +LDYE + ++ D LN + IDI D N+ + S + E IG L+++++A D + + + + + N F I N+ SIFL K L T++ + +T D ++ +S+ ++V F +N FK ++ EN P+G+ V+ + + + +IN ++ GN F I + K + + +D E + +TVK + I + NVT Sbjct: 193 PSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNP-PVFGSSHYQAGV---PEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGL--------ITVREPLDFEARRQYSLTVQ--ATDRGVPSLTGRAEAFIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQRSKVPNLSLIKVASALDRERIPSYNLTVSVSDNSGAPPTAEVQARSSVASLVIFVNDINDHPPVFEQQVYRVNLSEEVPPGSYVSGVSATDGDSGLNANLR---YSIVSGNGLGWFHISEHSGLVTTSAAGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTVLDVNDEKPVFSQPEGYEVS---VVENAPTGTELLVLGATDRDLGDNGTVRFSLQEAENDQRLFRLDPVSGRLSTASSLDREEQAFYCLSILATDLGSPPQSSTAQVNVSLLDINDNSPVFYPVQY-----FAHIQENEPGGSYVTTVSATDPDMGPNGTVKYSISAGDRSRFQIHAKSGV-------ISTKMALDREEKTAYQLQVVATDGGNLQSPNQAIVTVTVLDTQDNPPVFSQAAYSFVVFENVA---LGYH-VGSVSATTMDLNANISYLI---TTGDQRGMFAMNPVTGQLTTASVIDREEQSFYQLKIVASG---GAVTGDTVVNITVKDLND----------NAPHFLQAVESINAVENWQAGHSIFQAKAVDPDEGVNGRVLYSLKQNPKNLFTINE--QNGNISLLGALDVHAGSYQVEIVASDMGVPQLSSSILLT-VYVHDVNDNPPVFDQISYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYT--ITDGNNGDAFGIFPDGQLYIKSELDRELQDRYVLLVVASDRAVEPLSATVNVTVLLEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYAFEVTQ--PNFEL--HAVTGEITSTHKFDRESLMRRRGTAVFSFTVTAMDRGLPQP-LKDQATVHVYMKDINDNAPKFLKDFYQATVSETATNLTQVLRVSASDVD--------EGSNGLIHYSILKGNEERQFAIDSFSGQVTLVGKLDYEATSAYSLLIQAVDSGAIPLNSTCTLSIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGVNADLHYTITGSNN-HGTFSISPNTGSIFLAKKLDFETQS-LYKLNITAKDQGRPPRSSTMSVVIQVRDFNDNPPSFPPGDIFKSIV---ENIPLGTSVISVTAH---DPDADINGQLSYAIIQQMPRGNHFSIDEVKGTIYTSAEIDREFANLFELTVKANDQAVPIETRRYALKNVT 1516 HSP 4 Score: 69.707 bits (169), Expect = 6.296e-11 Identity = 226/1038 (21.77%), Postives = 419/1038 (40.37%), Query Frame = 1 Query: 1144 KTYFIQLIDVNEAPQ--GLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLE----LKDNTRLDYEKTPAYNLGIRVTDYGQ---ENIVTDFEIILEISDANERPEN-LSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTV---------FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNE--PPTKLAIDGSREIIINITENIQGY-QSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVL-IRAIDSG--GLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFI--IGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQ--------CFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDY---SNKSLQISKSSIIVLVSNNIKIQINE-DNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKI-VNNELLTDVNSLDVVVSNYITY-------FWVEILCRDDGQPSLSIQSRFYIQIINVND-GPT--AINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSN--SYFGISNSS--IYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNE---PPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSS-IFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKD---VMNLPENSPIGSKVLEI 4047 + YF ++DVN+ P ++ Y +++ EN+P GS + F++ D++ + + S + + + + QF ++ LK LD E YNL I+V D Q + ++ + + D N+ P LS IPEN PI ++ A D D NS + YTL NK GT+ D E Y +T+ D G P L+ S + +L+ N+N + + Y I EN + I V D D+ N Q+ ++ I ++ +T+ ++LD E + + ++ D + T + I + ++N+ P +L+ +N+ EN+ ++I + D DQ N + Y +L N + F + G L+ +Q D E+ +D VL + A D+G L+ + I + D ND +P+F ++ I + D L + + +SI+ + I + + I +D E + + G + S++ S + I D+N+ P F + V + + S + +TD SN L S S N+ K I+ + M PL +E F S + D S S + V+ + + P ++++ E+ MF P N + T T I + GE ++ I + + D + V +S + + W+E RD G P S + I ++++ND PT +++++ I TV A + + ++ N S F I++++ I + LD E + E V D+ + S+ ++ I ++E P +I + +E S +G + ++ +D + S + PF I N+ I +++ L + D+ V+ D + ++S +VTIF ++ + F ++ PE +GS+V ++ Sbjct: 1929 RAYF-NILDVNDNPPVFSMSSYSTSLMENLPLGSTVLVFNVTDAD-DGVNSQLSYSIASGDSL---GQFAVDKHGVLKTLKALDRESQSFYNLVIQVHDLPQPPTSRFTSTAQVSIILLDVNDNPPMFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTL------LNPSGNKFSIGTIDGEVHLTGELDREEVSNYSLTVVATDKGQPPLSSSTEVVVMVLDINDNNPVFAQAMY-----RVQIKEN--ILTGTDIIQVSAADNDEGTNGQVRYGIVGGNTHQEFRIDSVTGA-ITVAKSLDRETTPAYTLTVQATDRGSSPRTDSCTVAITLLDMNDFVPVFELS-----PYSVNVPENLGTLPRAILQVVARDDDQGPNSQLSYVLLGG-NEDNAFVLTASGE---LRVTQSLDREA---RDHFVLVVTAADAGSPALTGTGTINIIVDDIND----------NVPTFANNMYLTSIAEDARTGTDVLLVNASDADAAANAVISYSIIGGNSQFTINPSTGQIITSALLDRETKDNYTLVVVASDAGSPESLSSSTSVLVTITDVNDNPPRFQHHPYVTHIPSPTPPGSFVFAVTVTDADIGSNSELHYSLSG-----RNSEKFHIDPLRGAIMAAGPLSGASEVTF--SVHVKDGGSFPKTDSTTVTVRFANKADFP-KVRAKEQTF-MF---PENQPVGTLVTT-----------ITGSSLRGETLSYYIASGNLGDTFQIDPLTGQVSISQPLDFEKIQKYVVWIE--ARDGGFPPFSSYEKLDITVLDINDNAPTFEEDPFVSEILENLSPRKILTVSATDKDSGPNGQLDYEIVNGNQESSFTINHATGEIRSIRPLDREKISHYELTVKSSDKGSPSQSTSVKVIISILDENDNAPRFSQIFSAYVSENSPLGYTVTRVTTSDEDIGINAISRYSIVDTSLPFTINPNTGDIVISRPLN-REDTDRYRIRVSAHD---SGWTVSTDVTIFVTDINDNTPRFSRPSYYLDCPELPELGSRVTQV 2896 HSP 5 Score: 68.9366 bits (167), Expect = 9.340e-11 Identity = 44/145 (30.34%), Postives = 66/145 (45.52%), Query Frame = 1 Query: 5290 CEEIDECLFNFCLG------DSSRCIDLVND----FQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE--FDHFSCKNCSENFGVC 5676 C+ CL +G +S I + N+ QC C +G CEV ++ CL + C +G C + SC C G+ G C + I++C+ PC VC++ GF C C+ +TG CE ++ C C N G C Sbjct: 3813 CQNGGSCLRRLAVGSALKIQESLPVIIVANEPLQPSQCKCVPGYAGSWCEV-DIDECLPAPCHNGGTCHNLVGGFSCSCPEGFTGRACERDINECLPSPCKHGAVCQNFPGGFNCVCKTGYTGKMCESSVNYCECNPCF-NGGSC 3955 HSP 6 Score: 65.855 bits (159), Expect = 9.303e-10 Identity = 38/137 (27.74%), Postives = 60/137 (43.80%), Query Frame = 1 Query: 5305 ECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTC-------EVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKN 5691 E + L S ++ V+ C+ G ++G +C LK+ L V + C C+ G+ G C ID+C+ PC+ G C + + GF C+C + FTG CE D C + ++ VC N Sbjct: 3786 ESIKEILLRQSGVKVESVDHDPCIHGPCQNGGSCLRRLAVGSALKIQESLPVIIVANEPLQPSQCKCVPGYAGSWCEVDIDECLPAPCHNGGTCHNLVGGFSCSCPEGFTGRACERDINECLPSPCKHGAVCQNFPG 3922 HSP 7 Score: 64.3142 bits (155), Expect = 2.633e-9 Identity = 147/676 (21.75%), Postives = 277/676 (40.98%), Query Frame = 1 Query: 211 IHVAILDAND-PPT-NIQLSNWKVEENILVGSLVGQISVVDEDLDD----SFKCSVKSDSPFNVDA-NFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKII--ILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGE------LSAIDEDINELYSFQILILHTDSV-EIKHKNELWIKESAELNYESSYVNYFVVGAY---KDQILIFNKTYFIQ--LIDVNEAPQGLTLYP--STVTENIPSGSVIGKFSIL--DSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTL--DVNEKDFYIEN--NKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQII------SDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNE 2109 + + + D ND PP + VEENI GS + Q++ +D D ++ +D F +D + +L LD E ++++ +++ D SS + + I+++D+N+ + + E++ G+ + I D D N + + D + + +T + F L + +++ Y+ ++V + S ++ IL+V++NP + S+ + L+E N LG ++ D+ +N S+ I DS+ + +K L+ ES V+ + + F T + L+DVN+ P + L P + + EN P +V+ K DS NS IE L F I E+ LD E+ Y+L + TD GQ + + E+++ + D N+ ++ QI EN G I ++A DND+ N + Y + ++F I++ + D E P Y +T+ D G S T I +L+ N+ + Y ++ EN + A + V D D N Q+ ++++ F++ E++ + Q+LD E ++F + + D + T I I V+++N+ Sbjct: 1726 VEITLQDINDNPPVFPTDTLDLTVEENIGDGSKIMQLTAMDADEGANALVTYALISGADDSFRIDPESGDLIATKRLDREHRSKYSLLVRADDGLQSSDM-RINITISDVNDHTPRF----SRPVYSFDIPEDTTPGSLVAAILATDDDSGVNGEISYVVEEDD---------GDGVFFLNLVTGV---FNLTRALDYETQQYYILTVRAEDGGGQSTTIRAYFNILDVNDNPPVFSM--SSYSTSLME----NLPLGSTVLVFNVTDADDGVNSQLSYS--IASGDSLGQFAVDKHGVLKTLKALDRESQSFYNLVIQVHDLPQPPTSRFTSTAQVSIILLDVNDNPP-MFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLN--PSGNKFSIGTIDGEVHLTGELDREEVSNYSLTVVATDKGQPPLSSSTEVVVMVLDINDNNPVFAQAMYRVQIKENILTGTDIIQVSAADNDEGTNGQVRYGIVGGNTHQEFRIDSVTGAITVAKSLDRETTPAYTLTVQATDRGSSPRTDSCTVAITLLDMNDFVPVFELSPYS-----VNVPENLGT-LPRAILQVVARDDDQGPNSQLSYVLLGGNEDNAFVLTASGELR--------VTQSLDREARDHFVLVVTAADAGSPALTGTGTINIIVDDIND 2359 HSP 8 Score: 60.8474 bits (146), Expect = 2.622e-8 Identity = 181/818 (22.13%), Postives = 320/818 (39.12%), Query Frame = 1 Query: 157 LEILAKDLDVPKNSKLFIIHVAILDAND-PPTNIQLSNWK-VEENILVGSLVGQISVVDEDLDD----SFKCSVKSDSPFNVDANFNLF-TKAPLDYETQARFEVIIECLDHENSSVINKHEISVT--DINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSE-IVKIIILNVDEN-PTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLI-----------DVNEAPQGLTL--YPSTVTENIPSGSVIGKF--SILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ-----IPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYIE--NNKLLSGTVFDHEN---RPG---YQITITVFDNGDPK-LNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNI----FQYDLTINQTLDYEQNNYFEINIEINDMK----NFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND-PPT 2445 L ILA DL P S ++V++LD ND P + + ++EN GS V +S D D+ + S S F + A + TK LD E + +++ + D N N+ ++VT D + P ++ ++ EN G +G + D N + + + D + + Q +R+ + ++Q+ + + +V I + ++++N P L+ +S + +E + +S+ + A+D D E + ++L S++ KN I E N S + V A Q+ I + + DVN+ P Y T++E+ P S K S DS N I + + QL +K + LD E Y L + +D E + + + + D N +N L N+ E + G + ++A D D N + Y +V + +F + ++ S FD E+ R G + T+T D G P+ L T + + + N+N +KD Y + V N + V D D+ N I + + K +E + F +T+ LDYE + + + I+ D N T + I I EN N P + + +++ EN++ + +++ TD D N + Y+I N + F S ++L + F+ +S K+ I A D G S + V I ++D ND PP+ Sbjct: 657 LSILATDLGSPPQSSTAQVNVSLLDINDNSPVFYPVQYFAHIQENEPGGSYVTTVSATDPDMGPNGTVKYSISAGDRSRFQIHAKSGVISTKMALDREEKTAYQLQVVATDGGNLQSPNQAIVTVTVLDTQDNP-PVFSQAAYSFVVF---ENVALGYHVGSVSATTMDLNANISYLITTGDQRGMF------------AMNPVTGQLTTASVIDREEQSFYQLKIVASGGAVTGDTVVNITVKDLNDNAPHFLQAVESIN---AVENWQAGHSIFQAKAVDPD--EGVNGRVLY----SLKQNPKNLFTINEQ---NGNISLLGALDVHAGSYQVEIVASDMGVPQLSSSILLTVYVHDVNDNPPVFDQISYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTITDGNNGDAFGIFPDGQLYIK--SELDRELQDRYVLLVVASDRAVEPLSATVNVTVLLEDVN---DNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYAFEVTQPNFELHAVTGEITSTHKFDRESLMRRRGTAVFSFTVTAMDRGLPQPLKDQATVHVYMKDINDNAPKFLKDFY--QATVSETATN-----LTQVLRVSASDVDEGSNGLI-----HYSILKGNEERQFAIDSFSGQVTLVGKLDYEATSAYSLLIQAVDSGAIPLNSTCTLSIDILDENDNTPSFPKST-----LFVDVLENMRIGELVSSVTATDSDSGVNADLHYTITGS-NNHGTFSISPNTGSIFLAKKLDFETQSL----YKLNITAKDQGRPPRSSTMSVVIQVRDFNDNPPS 1419
BLAST of Protocadherin Fat 4 vs. Ensembl Mouse
Match: Pcdhb10 (protocadherin beta 10 [Source:MGI Symbol;Acc:MGI:2136745]) HSP 1 Score: 88.1965 bits (217), Expect = 7.939e-17 Identity = 96/391 (24.55%), Postives = 175/391 (44.76%), Query Frame = 1 Query: 1156 IQLIDVNE-APQGL-TLYPSTVTENIPSGSVIGKFSI--LDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLS--NNQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYIENN-----KLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDD--KINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFT----AIMKIFIFVENVNEP----PTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNC 2253 I+++D+N+ APQ + +LY + EN P +++ S LD+ + + Q ++ F+I + E++ LD+E TP YN+ I TD G +++++ D N+ L++S N+ IPEN P ++A+ + D D +N +V ++ NE F +++ L++ D E++ Y ITI+V D G P+L T +++ + N+N + Y I ENN + TI+ + D I ++ + L N L + LDYE FE ++ D + A++ + + +N NEP P + + +E++ E GY + + D D QN + + +L Sbjct: 230 IEVVDINDNAPQFIQSLYEVQILENSPLDALVATVSARDLDAGIYGKVAYSLFQDDGISQPFVIDEITGEIRLKGALDFEATPYYNMEIVATDPG--GFSGKCTVVIQVVDVNDNAPKLTISSLNSSIPENAP-ETVVAVFSVSDPDSGENGRMVCSIQ-NELPFLLKSTFENYYTLVTEGTLDRESKAEYNITISVTDLGTPRLTTQHTITVQVSDINDNAPTFTRTSY-----TMFIRENNSPALHIGTISATDSDAGSNAHITYSLLPPHDPQLTLTSLVSINEDNGQLFALRALDYEALRAFEFHVRATDRGSPALSSQALVLVVVLDDNDNEPFVLYPLQNSSAPCKELVPRAAE--AGYL-VTKVVAVDRDSGQNAWLSFQLLKA 608 HSP 2 Score: 68.9366 bits (167), Expect = 6.502e-11 Identity = 116/474 (24.47%), Postives = 204/474 (43.04%), Query Frame = 1 Query: 1432 ENIVTDFEIILEISDAN----ERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLV--YTLDVNEKDFYI---------ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFD--DKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDG-SREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND-PPTVAGLNFTMIPSFVEKD----FIIGKVNVFDEDNLSTYNQIECSIIKP----LKWFSILNISQ-NLEIVTTATRFIDE---KFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEP 2754 EN V F+ L+++D N E P+ L +IPE+ G + AQD D S V YT+ N F++ + +L+ D E +P + +T D G P + + IE+++ N+N I+ Y EV I+EN+ L+ AT++ + D K+ + D+ + + I I ++ + LD+E Y+ + I D F+ + I V +VN+ KL I + I N E + +A F +DPD +N + SI N L K F N L D ES +I + + + + L+ + + + D ND PT ++TM F+ ++ IG ++ D D S + I S++ P L S+++I++ N ++ A R +D + + ++ + G + S + ++D +NEP Sbjct: 111 ENPVQFFQTELQLTDINDHSPEFPDRKMLL--KIPESAQPGTTFPLKAAQDPDIGSNAVQNYTVSPN-LHFHVVTLSRSDGRKYPELVLDRALDREEQPELTLILTALDGGAPPRSGTTEVHIEVVDINDNAPQFIQSLY----EV-QILENSPLDALVATVSARDLDAGIYGKVAYSLFQDDG---ISQPFVIDEI-TGEIRLKGALDFEATPYYNMEIVATDPGGFSGKCTVVIQVVDVNDNAPKLTISSLNSSIPENAPETV-----VAVFSVSDPDSGENGRMVCSIQNELPFLLKSTFEN---YYTLVTEGTLDRESKAEYNITISVTDLGTPRLTTQHTITVQVSDINDNAPTFTRTSYTM---FIRENNSPALHIGTISATDSDAGSNAH-ITYSLLPPHDPQLTLTSLVSINEDNGQLF--ALRALDYEALRAFEFHVRATDRGSPALSSQALVLVVVLDDNDNEP 558
BLAST of Protocadherin Fat 4 vs. UniProt/SwissProt
Match: sp|Q9UM47|NOTC3_HUMAN (Neurogenic locus notch homolog protein 3 OS=Homo sapiens OX=9606 GN=NOTCH3 PE=1 SV=2) HSP 1 Score: 108.612 bits (270), Expect = 5.625e-22 Identity = 64/169 (37.87%), Postives = 87/169 (51.48%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFC--LGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 +CH + SN CH +A C +N +N C C PGF G G+ +++DEC N C LG RC++ F C CG +G CE VN CL C + C D +C+C++G+ G C ID+C PC GVC+D +NGF C C F+G C+ D C Sbjct: 348 LCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPCEHLG---RCVNTQGSFLCQCGRGYTGPRCET-DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDEC 511 HSP 2 Score: 91.2781 bits (225), Expect = 9.817e-17 Identity = 55/179 (30.73%), Postives = 84/179 (46.93%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 + I S+ C CK + F C C GF +GS+C+ ++DEC C + ++C+D + ++C C G C+ V+ C C HG C D SC C G+ G C +D+C PC G C D ++ ++C C TG+ CE + C + FGVC + N+ Sbjct: 468 VDIDECQSSPCVNGGVCKDRV--NGFSCTCPSGF--SGSTCQLDVDECASTPCR-NGAKCVDQPDGYECRCAEGFEGTLCD-RNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINR 640 HSP 3 Score: 87.8113 bits (216), Expect = 1.069e-15 Identity = 56/177 (31.64%), Postives = 81/177 (45.76%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 ++C N + C + C D F C C PG+ G+ CE ++DEC C +C+DLV+ + C C S +G CEV ++ C + C G+CRD C+C G+ G CN I++C PC G C D NGF C C C C + + G+C + Sbjct: 540 TLCDRNVDDCSPDP-CHHGRCVDGIASFSCACAPGY--TGTRCESQVDECRSQPCR-HGGKCLDLVDKYLCRCPSGTTGVNCEV-NIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGICYD 711 HSP 4 Score: 87.4261 bits (215), Expect = 1.727e-15 Identity = 58/173 (33.53%), Postives = 77/173 (44.51%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS----CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLN 5682 S+ C A C + F C C PG+ G SC ++DEC C++ F+C C + +G CE V C S C +G CR C CL G+EG +C ++DDC G C G C D +N + C C +TG FC D C+ N N G C N Sbjct: 125 SSPCAHGARCSVGP-DGRFLCSCPPGY--QGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP-CAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFN 293 HSP 5 Score: 83.1889 bits (204), Expect = 2.611e-14 Identity = 65/186 (34.95%), Postives = 79/186 (42.47%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE--FDHFSCKNCSENFGVCLNLKNKNQYCL 5709 C + N C N D F C C PGF G + ++DECL N C C D V F C C G CE + C S C +G C D SCLC G+ G C D C+ PC GVC A GF C C ++FTG C+ D S + C +N G C+ YCL Sbjct: 846 CDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCA-RDVDECLSNPC--GPGTCTDHVASFTCTCPPGYGGFHCE-QDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPC-QNGGRCV---QTGAYCL 1023 HSP 6 Score: 83.1889 bits (204), Expect = 2.962e-14 Identity = 54/167 (32.34%), Postives = 81/167 (48.50%), Query Frame = 1 Query: 5200 CHRNATCK-SNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLC-LKSDCVH--GICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C TC+ S +L + C C PGF G +CE +D+C + CL + C+D VN + C C + +G+ C V+ C L+ + H G C + +SC+C++GW G C+++IDDC C C D + F C C TG+ C D N +C Sbjct: 206 CRNGGTCRQSGDLT--YDCACLPGF--EGQNCEVNVDDCPGHRCL-NGGTCVDGVNTYNCQCPPEWTGQFC-TEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAIC 366 HSP 7 Score: 79.7221 bits (195), Expect = 3.280e-13 Identity = 56/175 (32.00%), Postives = 73/175 (41.71%), Query Frame = 1 Query: 5179 CHFNSNKCHRN----ATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS---CLCLSGWEGIDCNKSI--DDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C N + C N C+ + + C C PGF G + E I+EC + C G+ C+D N F+CLC C + + C C HGIC D C+C GW G C++S+ D C PC G C GF C C G CE N E+ G C Sbjct: 617 CEVNIDDCASNPCTFGVCRDGI--NRYDCVCQPGFTGPLCNVE-INECASSPC-GEGGSCVDGENGFRCLCPPGSLPPLC-LPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRC 786 HSP 8 Score: 73.1738 bits (178), Expect = 3.428e-11 Identity = 51/164 (31.10%), Postives = 72/164 (43.90%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS------CLCLSGWEGIDCNKSIDDC-IG-DPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C N CH TC N L C C G+ G S + ID+C C ++ C D V F C C ++G C + + C+ + C D N C C G+ G C++ +D+C IG +PC G C + F+C C + +TG CE D C Sbjct: 278 CQLQPNACHNGGTC-FNTLGGH-SCVCVNGWTGESCS-QNIDDCATAVCFHGAT-CHDRVASFYCACPMGKTGLLCHL--DDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNEC 435 HSP 9 Score: 70.8626 bits (172), Expect = 1.826e-10 Identity = 43/145 (29.66%), Postives = 63/145 (43.45%), Query Frame = 1 Query: 5251 CFCNPGFVGN---------GSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C C PG+ G + +I L C +C+D + C+C R+G CE +V+ CL C HG CR C CL G+ G +C +D+C PC G C D + ++C+C G+ CE + C Sbjct: 1022 CLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQA-GGQCVDEDSSHYCVCPEGRTGSHCE-QEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1164 HSP 10 Score: 69.3218 bits (168), Expect = 4.603e-10 Identity = 51/169 (30.18%), Postives = 67/169 (39.64%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQ-CLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 S C TC S+ + F C C PG G CE + C N C RC C C G C+ + C HGIC + SC C G+ G C++ I+DC +PC G C+D + F C+C F G C D C + G C + Sbjct: 740 SQPCRAGGTCSSDGMG--FHCTCPPGV--QGRQCELLSPCTPNPC-EHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTD 903 HSP 11 Score: 65.4698 bits (158), Expect = 7.954e-9 Identity = 48/155 (30.97%), Postives = 62/155 (40.00%), Query Frame = 1 Query: 5242 EFQCFCNPGFVGNGSSCEEIDECLFNFCLGD---SSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI-CRDDNS----CLCLSGWEGIDCNKSIDDC-IGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVC 5676 E C C PG+V G C+ D C C G S + F C C G C + + CL S C HG C C C G++G C +D+C +G+PC G C + F C C +TG CE C + N G C Sbjct: 62 EAACLCPPGWV--GERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSL--PDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTC 212 HSP 12 Score: 60.077 bits (144), Expect = 2.903e-7 Identity = 52/179 (29.05%), Postives = 67/179 (37.43%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRC------IDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD-------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN-----GFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 S C +C +L + C C PG +G E D+C L RC +DLV F+C C +G CE +N C C RD CLC +G+ G C + C PC G C + F C+C Q F G CE SC+ GV Sbjct: 1128 SQPCQHGGSCI--DLVARYLCSCPPGTLGVLCEINE-DDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEA-DINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGV 1302 HSP 13 Score: 59.3066 bits (142), Expect = 5.831e-7 Identity = 48/146 (32.88%), Postives = 62/146 (42.47%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDP-------CNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN 5652 C C G GS CE E+D CL C + C + + C C +G CE V+ C C HG C D + C C G G+ C + DDC P C G C D + GF C C +TG+ CE D C++ Sbjct: 1070 CVCPEG--RTGSHCEQEVDPCLAQPCQHGGT-CRGYMGGYMCECLPGYNGDNCED-DVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRS 1211
BLAST of Protocadherin Fat 4 vs. UniProt/SwissProt
Match: sp|Q61982|NOTC3_MOUSE (Neurogenic locus notch homolog protein 3 OS=Mus musculus OX=10090 GN=Notch3 PE=1 SV=1) HSP 1 Score: 107.071 bits (266), Expect = 1.888e-21 Identity = 63/169 (37.28%), Postives = 87/169 (51.48%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFC--LGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 +CH + SN CH +A C +N ++ C C PGF G G+ +++DEC N C LG RC++ F C CG +G CE VN CL C + C D +C+C++G+ G C ID+C PC GVC+D +NGF C C F+G C+ D C Sbjct: 349 LCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTG-GACDQDVDECSIGANPCEHLG---RCVNTQGSFLCQCGRGYTGPRCET-DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSMCQLDVDEC 512 HSP 2 Score: 92.0485 bits (227), Expect = 5.778e-17 Identity = 57/179 (31.84%), Postives = 84/179 (46.93%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 + I S+ C CK + F C C GF +GS C+ ++DEC C + ++C+D + ++C C G CE V+ C C HG C D SC C G+ GI C +D+C PC G C D ++ ++C C TG+ CE + C + FGVC + N+ Sbjct: 469 VDIDECQSSPCVNGGVCKDRV--NGFSCTCPSGF--SGSMCQLDVDECASTPCR-NGAKCVDQPDGYECRCAEGFEGTLCE-RNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFGVCRDGINR 641 HSP 3 Score: 88.5817 bits (218), Expect = 6.963e-16 Identity = 60/174 (34.48%), Postives = 78/174 (44.83%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS----CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLNL 5685 S C A C + F C C PG+ G SC+ +IDEC C++ F+C C +G CE V C S C +G CR + C CL G+EG +C ++DDC G C G C D +N + C C +TG FC D C+ N N G C NL Sbjct: 126 SRPCVHGAPCSVGP-DGRFACACPPGY--QGQSCQSDIDECRSGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCEN-PVVPCAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNL 295 HSP 4 Score: 84.7297 bits (208), Expect = 9.927e-15 Identity = 56/175 (32.00%), Postives = 79/175 (45.14%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 ++C N + C + C D F C C PG+ G CE ++DEC C +C+DLV+ + C C +G CEV ++ C + C G+CRD C+C G+ G CN I++C PC G C D NGF C C C + C + + GVC Sbjct: 541 TLCERNVDDCSPDP-CHHGRCVDGIASFSCACAPGY--TGIRCESQVDECRSQPCRY-GGKCLDLVDKYLCRCPPGTTGVNCEV-NIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCSHGVC 710 HSP 5 Score: 83.1889 bits (204), Expect = 2.864e-14 Identity = 52/166 (31.33%), Postives = 80/166 (48.19%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLC-LKSDCVH--GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C TC+ + + + C C PGF G +CE +D+C + CL + C+D VN + C C + +G+ C V+ C L+ + H G C + +SC+C++GW G C+++IDDC C C D + F C C TG+ C D N +C Sbjct: 207 CRNGGTCRQSS-DVTYDCACLPGF--EGQNCEVNVDDCPGHRCL-NGGTCVDGVNTYNCQCPPEWTGQFC-TEDVDECQLQPNACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAIC 367 HSP 6 Score: 78.9518 bits (193), Expect = 5.078e-13 Identity = 57/176 (32.39%), Postives = 73/176 (41.48%), Query Frame = 1 Query: 5179 CHFNSNKCHRN----ATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNL-CLKSDCVHGICRDDNS---CLCLSGWEGIDCNKSI--DDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C N + C N C+ + + C C PGF G + E I+EC + C G+ C+D N F CLC C L N C C HG+C D C+C GW G C++S+ D C PC G C GF C C F G CE + E+ G C Sbjct: 618 CEVNIDDCASNPCTFGVCRDGI--NRYDCVCQPGFTGPLCNVE-INECASSPC-GEGGSCVDGENGFHCLCPPGSLPPLC--LPANHPCAHKPCSHGVCHDAPGGFRCVCEPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFRCTCAPGFQGHQCEVLSPCTPSLCEHGGHC 787 HSP 7 Score: 75.485 bits (184), Expect = 7.115e-12 Identity = 50/151 (33.11%), Postives = 65/151 (43.05%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 + N C +C+ F C C GF G + ++DECL + C C D V F C C G CE+ + C S C +G C D SCLC G+ G C D C PC G+C GF C C++ FTG C+ Sbjct: 855 DPNPCLHGGSCQDGV--GSFSCSCLDGFAGPRCA-RDVDECLSSPC--GPGTCTDHVASFTCACPPGYGGFHCEI-DLPDCSPSSCFNGGTCVDGVSSFSCLCRPGYTGTHCQYEADPCFSRPCLHGGICNPTHPGFECTCREGFTGSQCQ 999 HSP 8 Score: 70.0922 bits (170), Expect = 2.534e-10 Identity = 50/168 (29.76%), Postives = 68/168 (40.48%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 S C TC S+ + F+C C PGF G CE + C + C D C C G C+ S C HG C + + C+C G+ G C++ IDDC +PC G C+D + F C+C F G C D C + G C + Sbjct: 741 SQPCQAGGTCTSDGIG--FRCTCAPGF--QGHQCEVLSPCTPSLCEHGGHCESDPDRLTVCSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGNFRCICHRGYTGPFCDQDIDDCDPNPCLHGGSCQDGVGSFSCSCLDGFAGPRCARDVDECLSSPCGPGTCTD 904 HSP 9 Score: 67.0106 bits (162), Expect = 2.179e-9 Identity = 42/145 (28.97%), Postives = 62/145 (42.76%), Query Frame = 1 Query: 5251 CFCNPGFVGN---------GSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 C C PG+ G + ++ L C + +CID C+C R+G CE +V+ C C HG CR C C +G+ G C +ID+C PC G C D + ++C+C G+ CE + C Sbjct: 1023 CICPPGWSGRLCDIQSLPCTEAAAQMGVRLEQLC-QEGGKCIDKGRSHYCVCPEGRTGSHCE-HEVDPCTAQPCQHGGTCRGYMGGYVCECPAGYAGDSCEDNIDECASQPCQNGGSCIDLVARYLCSCPPGTLGVLCEINEDDC 1165 HSP 10 Score: 63.1586 bits (152), Expect = 3.580e-8 Identity = 49/174 (28.16%), Postives = 68/174 (39.08%), Query Frame = 1 Query: 5185 FNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGD---SSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG----ICRDDN-SCLCLSGWEGIDCNKSIDDC-IGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVC 5676 + + C C + + E C C PG+V G C+ D C C G S + F C C G C + + C+ CVHG + D +C C G++G C ID+C G C G C + F C C +TG+ CE C + N G C Sbjct: 44 LDGSPCANGGRCTHQQPSLEAACLCLPGWV--GERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCLRGFQGPDCS--QPDPCVSRPCVHGAPCSVGPDGRFACACPPGYQGQSCQSDIDECRSGTTCRHGGTCLNTPGSFRCQCPLGYTGLLCENPVVPCAPSPCRNGGTC 213 HSP 11 Score: 58.151 bits (139), Expect = 1.211e-6 Identity = 50/184 (27.17%), Postives = 69/184 (37.50%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGN-----------GSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD-------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN-----GFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 S C +C +L + C C PG +G G S + +CL N C+DLV F+C C +G CE +N C C RD C+C G+ G C ++ C PC G C +L F C+C F G+ CE SC+ G+ Sbjct: 1129 SQPCQNGGSCI--DLVARYLCSCPPGTLGVLCEINEDDCDLGPSLDSGVQCLHN------GTCVDLVGGFRCNCPPGYTGLHCEA-DINECRPGACHAAHTRDCLQDPGGHFRCVCHPGFTGPRCQIALSPCESQPCQHGGQCRHSLGRGGGLTFTCHCVPPFWGLRCERVARSCRELQCPVGI 1303 HSP 12 Score: 57.3806 bits (137), Expect = 1.907e-6 Identity = 46/145 (31.72%), Postives = 63/145 (43.45%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDP-------CNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK 5649 C C G GS CE E+D C C + C + + C C + +G +CE ++ C C +G C D + C C G G+ C + DDC P C G C D + GF CNC +TG+ CE D C+ Sbjct: 1071 CVCPEG--RTGSHCEHEVDPCTAQPCQHGGT-CRGYMGGYVCECPAGYAGDSCED-NIDECASQPCQNGGSCIDLVARYLCSCPPGTLGVLCEINEDDCDLGPSLDSGVQCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECR 1211
BLAST of Protocadherin Fat 4 vs. UniProt/SwissProt
Match: sp|Q9R172|NOTC3_RAT (Neurogenic locus notch homolog protein 3 OS=Rattus norvegicus OX=10116 GN=Notch3 PE=2 SV=2) HSP 1 Score: 105.916 bits (263), Expect = 3.432e-21 Identity = 63/169 (37.28%), Postives = 87/169 (51.48%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFC--LGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 +CH + SN CH +A C +N ++ C C PGF G G+ +++DEC N C LG RC++ F C CG +G CE VN CL C + C D +C+C++G+ G C ID+C PC GVC+D +NGF C C F+G C+ D C Sbjct: 350 LCHLDDACVSNPCHEDAICDTNPVSGRAICTCPPGFTG-GACDQDVDECSIGANPCEHLG---RCVNTQGSFLCQCGRGYTGPRCET-DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTFCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDEC 513 HSP 2 Score: 93.2041 bits (230), Expect = 2.451e-17 Identity = 57/179 (31.84%), Postives = 85/179 (47.49%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 + I S+ C CK + F C C GF +GS+C+ ++DEC C + ++C+D + ++C C G CE V+ C C HG C D SC C G+ GI C +D+C PC G C D ++ ++C C TG+ CE + C + FGVC + N+ Sbjct: 470 VDIDECQSSPCVNGGVCKDRV--NGFSCTCPSGF--SGSTCQLDVDECASTPCR-NGAKCVDQPDGYECRCAEGFEGTLCE-RNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGIRCESQVDECRSQPCRYGGKCLDLVDKYLCRCPPGTTGVNCEVNIDDCASNPCTFGVCRDGINR 642 HSP 3 Score: 89.3521 bits (220), Expect = 4.134e-16 Identity = 60/174 (34.48%), Postives = 78/174 (44.83%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS----CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLNL 5685 S+ C A C + + C C PG+ G +C +IDEC CI+ F CLC +G CE V C S C +G CR + C CL G+EG +C ++DDC G C G C D +N + C C +TG FC D C+ N N G C NL Sbjct: 127 SSPCAHGAPCSVGS-DGRYACACPPGY--QGRNCRSDIDECRAGASCRHGGTCINTPGSFHCLCPLGYTGLLCENPIVP-CAPSPCRNGGTCRQSSDVTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNL 296 HSP 4 Score: 84.7297 bits (208), Expect = 9.050e-15 Identity = 56/175 (32.00%), Postives = 79/175 (45.14%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 ++C N + C + C D F C C PG+ G CE ++DEC C +C+DLV+ + C C +G CEV ++ C + C G+CRD C+C G+ G CN I++C PC G C D NGF C C C + C + + GVC Sbjct: 542 TLCERNVDDCSPDP-CHHGRCVDGIASFSCACAPGY--TGIRCESQVDECRSQPCRY-GGKCLDLVDKYLCRCPPGTTGVNCEV-NIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFHCLCPPGSLPPLCLPANHPCAHKPCSHGVC 711 HSP 5 Score: 83.1889 bits (204), Expect = 2.655e-14 Identity = 52/166 (31.33%), Postives = 80/166 (48.19%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLC-LKSDCVH--GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C TC+ + + + C C PGF G +CE +D+C + CL + C+D VN + C C + +G+ C V+ C L+ + H G C + +SC+C++GW G C+++IDDC C C D + F C C TG+ C D N +C Sbjct: 208 CRNGGTCRQSS-DVTYDCACLPGF--EGQNCEVNVDDCPGHRCL-NGGTCVDGVNTYNCQCPPEWTGQFC-TEDVDECQLQPNACHNGGTCFNLLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAIC 368 HSP 6 Score: 78.9518 bits (193), Expect = 6.008e-13 Identity = 57/176 (32.39%), Postives = 73/176 (41.48%), Query Frame = 1 Query: 5179 CHFNSNKCHRN----ATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNL-CLKSDCVHGICRDDN---SCLCLSGWEGIDCNKSI--DDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 C N + C N C+ + + C C PGF G + E I+EC + C G+ C+D N F CLC C L N C C HG+C D C+C GW G C++S+ D C PC G C GF C C F G CE + E+ G C Sbjct: 619 CEVNIDDCASNPCTFGVCRDGI--NRYDCVCQPGFTGPLCNVE-INECASSPC-GEGGSCVDGENGFHCLCPPGSLPPLC--LPANHPCAHKPCSHGVCHDAPGGFQCVCDPGWSGPRCSQSLAPDACESQPCQAGGTCTSDGIGFHCTCAPGFQGHQCEVLSPCTPSLCEHGGHC 788 HSP 7 Score: 77.411 bits (189), Expect = 1.704e-12 Identity = 50/151 (33.11%), Postives = 67/151 (44.37%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 + N C +C+ F C C GF G + ++DECL + C C D V F C C G CE ++ C S C +G C D SCLC G+ G C +D C PC G+C +GF C C++ FTG C+ Sbjct: 856 DPNPCLNGGSCQDGV--GSFSCSCLSGFAGPRCA-RDVDECLSSPC--GPGTCTDHVASFTCTCPPGYGGFHCETDLLD-CSPSSCFNGGTCVDGVNSFSCLCRPGYTGTHCQYKVDPCFSRPCLHGGICNPTHSGFECTCREGFTGNQCQ 1000 HSP 8 Score: 70.4774 bits (171), Expect = 2.037e-10 Identity = 50/168 (29.76%), Postives = 66/168 (39.29%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 S C TC S+ + F C C PGF G CE + C + C D C C G C+ S C HG C + C+C G+ G C++ IDDC +PC G C+D + F C+C F G C D C + G C + Sbjct: 742 SQPCQAGGTCTSDGIG--FHCTCAPGF--QGHQCEVLSPCTPSLCEHGGHCESDPDQLTVCSCPPGWQGPRCQQDVDECAGASPCGPHGTCTNLPGSFRCICHGGYTGPFCDQDIDDCDPNPCLNGGSCQDGVGSFSCSCLSGFAGPRCARDVDECLSSPCGPGTCTD 905 HSP 9 Score: 64.6994 bits (156), Expect = 1.221e-8 Identity = 34/106 (32.08%), Postives = 49/106 (46.23%), Query Frame = 1 Query: 5341 RCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 +CID + C+C R G CE +V+ C C HG CR C C +G+ G C +D+C PC G C D + ++C+C G+ CE + C Sbjct: 1062 QCIDKDHSHYCVCPEGRMGSHCE-QEVDPCTAQPCQHGGTCRGYMGGYVCECPTGYSGDSCEDDVDECASQPCQNGGSCIDLVAHYLCSCPPGTLGVLCEINEDDC 1166 HSP 10 Score: 64.6994 bits (156), Expect = 1.273e-8 Identity = 46/157 (29.30%), Postives = 64/157 (40.76%), Query Frame = 1 Query: 5185 FNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGD---SSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG----ICRDDN-SCLCLSGWEGIDCNKSIDDC-IGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 + + C C + + E C C PG+V G C+ D C C G S + V F C C G C + + C S C HG + D +C C G++G +C ID+C G C G C + F C C +TG+ CE Sbjct: 45 LDGSPCANGGRCTHQQPSREAACLCLPGWV--GERCQLEDPCHSGPCAGRGVCQSSVVAGVARFSCRCLRGFRGPDCSL--PDPCFSSPCAHGAPCSVGSDGRYACACPPGYQGRNCRSDIDECRAGASCRHGGTCINTPGSFHCLCPLGYTGLLCE 197 HSP 11 Score: 62.3882 bits (150), Expect = 5.315e-8 Identity = 52/184 (28.26%), Postives = 70/184 (38.04%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVG-----------NGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD-------DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALN-----GFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 S C +C +L + C C PG +G G S + CL N C+DLV F+C C +G CE +N C C RD C+CL G+ G C ++ C PC G C +L F C+C Q F G+ CE SC+ G+ Sbjct: 1130 SQPCQNGGSCI--DLVAHYLCSCPPGTLGVLCEINEDDCGPGPSLDSGLRCLHN------GTCVDLVGGFRCNCPPGYTGLHCEA-DINECRPGTCHAAHTRDCLQDPGGHFRCICLPGFTGPRCQTALFPCESQPCQHGGQCRPSLGRGGGLTFTCHCVQPFWGLRCERVARSCRELQCPVGI 1304 HSP 12 Score: 59.3066 bits (142), Expect = 4.847e-7 Identity = 48/145 (33.10%), Postives = 64/145 (44.14%), Query Frame = 1 Query: 5251 CFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDP-------CNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK 5649 C C G +G S CE E+D C C + C + + C C + SG +CE V+ C C +G C D + C C G G+ C + DDC P C G C D + GF CNC +TG+ CE D C+ Sbjct: 1072 CVCPEGRMG--SHCEQEVDPCTAQPCQHGGT-CRGYMGGYVCECPTGYSGDSCED-DVDECASQPCQNGGSCIDLVAHYLCSCPPGTLGVLCEINEDDCGPGPSLDSGLRCLHNGTCVDLVGGFRCNCPPGYTGLHCEADINECR 1212
BLAST of Protocadherin Fat 4 vs. UniProt/SwissProt
Match: sp|Q6V0I7|FAT4_HUMAN (Protocadherin Fat 4 OS=Homo sapiens OX=9606 GN=FAT4 PE=1 SV=2) HSP 1 Score: 104.76 bits (260), Expect = 1.057e-20 Identity = 282/1309 (21.54%), Postives = 522/1309 (39.88%), Query Frame = 1 Query: 142 TNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWK--VEENILVGSLVGQISVVDEDLDDSFKCSVK---SDSPFNVDANFNLFT-KAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINEAPDKI---YVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--------------NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNN-------NSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNE----LWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY---FIQLIDVNE------APQGLTLYPSTVTENIPSGSVIGKFSILDSNL--NSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFY---IENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNE--PPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSI----LNCLNCNEKFEFSNGG-SKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND-PPTVAGLNFTMIPSFVEK-DFIIGKVNVFDEDNLSTYNQIECSIIK--PLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDIN-NEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVS---NNIKIQINEDNSFMLTDPLDYET----ENNFLISFTLIDKNSNQSINLK------VQILDVNE-APSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKI-VNNELLTDVNSLDVVVSNYITY-----FWVEILCRDDGQPSLSIQSRFYIQIINVNDG----PTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSY--FGIS--NSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQ--IDIEDVNEPPENVKISN--DQWNEKSEIGLLIANLSANDPEG 3768 T L + +D PK ++V + D ND P S+++ V E+ +VGS V Q++ D D + + +PF +D L T + PLD+E + ++ + ++ +D S+ + E I + D+N+ + Y T+ + +EN++ GT + ++ D D N+ F S+ V L+ I++ L + ER +SV+D + S + ++I D N + L EE + +SA D D + + I+ + + H +E + S L+ E + + A +DQ + +Y + L+DVN+ P+G Y +V EN P+G+ + D +L N T+ + T F + L + LD E+ Y+L + TD G + I + + D N+ I ENEP G I ++A D D N T+ Y++ ++ + ++ + + D E + YQ+ I D G+ + I +L++ +NP + + Y F + EN L +++ D + I+ I + + QK N LT +D E+ +++++ + + T + I V+++N+ P AI+ +N+ EN Q SI DPD+ N ++ YS+ N NEK NG S L + Y+ I++L + LS + + + + D ND P L++ + S E + KV D+D+ + +I +I + F I Q L I + R + ++++ + + ++ + S T + + +ED+N N P S N+T F E +G++ + + ++ S +V + I +I + F D E+ + SFT+I + LK V + D+N+ AP +K F + T+ E + + A+D D N + ++SI+K + D S V + + Y + + I D G L+ I I++ ND P + ++ L ++ +++V A ++ D + G+N++ F IS SI++AK+LD+ET + + + DQ SS I + D N+ P + + E IG + +++A+DP+ Sbjct: 213 TPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSR--YASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPN---------------LSLIKVASAL--DRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHSGLVTTGSSGGLDRELASQIVLNISA-RDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEG---YDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYS-----FVVFENVALGYHVGSVSASTMDLNSNISYLITTGD-----QKGMFAINQVTGQLTTANVIDREEQSFYQLKV-VASGGTVTGDTMVNITVKDLNDNSPHFLQAIES-----VNVVENWQAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAINEK----NGTISLLGPLDVHAGSYQ------IEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGAN-GEIAYTIAEGNTGDAFGIFPDGQ-LYIKSELDRELQDRYVLMVVA--SDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITNTHQF------DRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQ-ATISESAANLTQVLRVSASDVDEG------------NNGLIHYSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDA 1449 HSP 2 Score: 93.2041 bits (230), Expect = 3.094e-17 Identity = 52/150 (34.67%), Postives = 79/150 (52.67%), Query Frame = 1 Query: 5224 SNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS 5658 +NE F C C PG+ G S CE +IDECL + C + C +LV F C C +GR CE +N CL+S C +G IC++ +C+C +G+ G C S++ C +PC G C+ ++ + C+C G CE + + + S Sbjct: 3839 ANEPLQPFLCKCLPGYAG--SWCEIDIDECLPSPCHSGGT-CHNLVGGFSCSCPDGFTGRACE-RDINECLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCFNGGSCQSGVDSYYCHCPFGVFGKHCELNSYGFEELS 3984 HSP 3 Score: 91.2781 bits (225), Expect = 1.236e-16 Identity = 248/1111 (22.32%), Postives = 461/1111 (41.49%), Query Frame = 1 Query: 1144 KTYFIQLIDVNEAPQGLTL--YPSTVTENIPSGSVIGKFSILDSN--LNSTIEKCSLQLITFNEIFLISQFQLE----LKDNTRLDYEKTPAYNLGIRVTDYGQ---ENIVTDFEIILEISDANERPEN-LSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTV---------FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFA-TITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNE--PPTKLAIDGSREIIINITENIQGY-QSIANFITTDPDQNDVIKYS-ILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND--PPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDY---SNKSLQISKSSIIVLVSNNIKIQINE-DNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDV-VVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAIN---YLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSN--SYFGISNSS--IYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNE---PPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSS-IFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDV---MNLPENSPIGSKVLEIQINFLSNFMPNINCEIF----SDGNFFII-VDFKVLLNKS-LDYET---------NSHIMVTVKCFQNKLQILKKLSTTINVTD 4254 + YF ++DVN+ P +L Y +++ EN+P GS + F++ D++ +NS + + + + + + QF ++ LK LD E YNL ++V D Q + ++ + + D N+ P LS IPEN PI ++ A D D NS + YTL NK GT+ D E Y +T+ D G P L+ S + +L+ N+N I + Y K E+ NE +T I VF D D+ N Q+ ++ I ++ +T+ + LD E+ + + ++ D + T + I + ++N+ P +L+ +N+ EN+ ++I + D D+ K S +L N + F S G L +Q D E+ + ++I A DSG L+ + + + D ND P + FT IP + VN D D ++ N + II F+I N S +I+T+A +D + D + + C + G + S++ S + + D+N+ P F + V + + S + +TD N L S S N+ K I+ + M PL+ +E F S + D S S + V+ ++ + P ++++ E+ E P + + T + + + I +G + N + + ++ LD + Y+ W+E RD G P S + I +++VND +++++ I TV A+ + + ++ N + F I++++ I + LD E + + D+ + S+ ++ I ++E P +I + E S +G + ++ +D + S + PF I ++ I +++ L + D+ V+ D + ++S +VTIF ++ + F ++ PE + IGSKV ++ F ++ N ++F S +F I + NK L Y+ N H + + K ++ + + TIN+ D Sbjct: 1929 RVYF-NILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINS---QLTYSIASGDSL---GQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTL------LNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALY--KVEI------NENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGA-ITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELS-----PYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGE---LGVTQSLDRETK--ERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDAD--ASKNAV-IRIIGGNSQFTI-NPSTG-QIITSA--LLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSG-----RNSEKFHIDPLRGAIMAAGPLNGASEVTF--SVHVKDGGSFPKTDSTTVTVRFVNKADFP-KVRAKEQTFMFPENQPVSSLVTTITGS-----SLRGEPMSYYIASGNLGNTFQIDQLTGQVSIS-QPLDFEKIQKYVV--WIE--ARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTINPSTGDIVISRPLN-REDTDRYRIRVSAHD---SGWTVSTDVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQV---FATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVD 2975 HSP 4 Score: 82.4185 bits (202), Expect = 6.200e-14 Identity = 136/551 (24.68%), Postives = 241/551 (43.74%), Query Frame = 1 Query: 736 EIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINE----LYSFQILI----LHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKD--QILIFNKTYFIQLIDVNE-APQGLT-LYPSTVTENIPSGSVIGKFSI--LDSNLNSTIEKCSLQLITFNE--IFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDV--NEKDFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFH-IMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMK-----NFTAIMKIFIFVENVNE------PPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILN 2250 ++ I+ EL + E Q + +DR LS V + ++ D N N + EE + +G++SA+D+D YSF+++ LH S EI + ++ + +ES ++ ++ V+ + Q L T + + D+N+ AP+ L Y +T++E+ + + + + S +D N I +I NE F I ++ +LDYE TPAY+L I+ D G + + + ++I D N+ + S + EN IG L++ + A D+D N+ L Y++ N F I N +G++F D E + Y++ IT D G P + + + I + + N+NP ++F I+EN + + ++T +PD D IN Q+ + + ++ N F D + N +D E N FE+ ++ ND A+ + I V ++N+ LA D S I +T + DPD+ N I+Y I+N Sbjct: 1051 QLYIKSEL--DRELQDRYVLMVVASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSFEMVQPDFELHAISGEITNTHQ-FDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIH---YSIIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPN---TGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPG------DIFKSIVENIPIGTSVISVTAHDPDAD--INGQL-----SYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAADPSAVIGSVLT----------TIMAADPDEGANGEIEYEIIN 1569 HSP 5 Score: 77.411 bits (189), Expect = 1.763e-12 Identity = 144/710 (20.28%), Postives = 286/710 (40.28%), Query Frame = 1 Query: 1234 GSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ--IPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVF-HIMENNELEMTFATITVFE---PDFDDKINCQIISDN-SRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND---------MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG---GLSIDLEVPISIQDANDPPTV----AGLNFTMI---PSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKS-SIIVLVSNNIKIQINEDNSFMLTD-PLDYETENNFLISFTLIDKNSNQSIN---LKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLT 3252 G+ G+F LD LN + E L L++ LD E TP Y L + V D G+ ++ + + D N+ P S+ Q +PE+ +G + + A D D+ N+ + Y L F + E + D E R Y +T+ D G P L I++L+ N+N + ++K +Y T + + EN ++ A +TV + P + I+ QI+ N R + S++ N+ + + LD E+ + + + ++D ++ +++ + IFV ++N+ P + R +N++E ++ TD D N ++YSI++ N F S + S D E + I + I A D G +S ++ +++ D ND V G + +++ P+ E + ++ ++ E + + F + +S L +++ R ++ F + + + G + +S+ +++ DIN+ F + V + N G + ++ L + + + + + Q+N + + T LD E + + + D + QS N + + +LD + P + +FE H+ + A+ D N +I +I G+ + V +L T Sbjct: 179 GNEAGRFR-LDITLNPSGEGAFLHLVS----------------KGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTPFQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDN-DPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEVQSSKVPNLSL--IKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYR---VNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSG-NGLGWFHISEHSGLVTTGSSGGLDRE--LASQIVLNISARDQGVHPKVSY-AQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDR--RSFRLDPVSGRLSTISSLDRE-EQAFYSLLVLATDLG-SPPQSSMARINVSLLDINDNSPVF---YPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNS----NISYLITTGDQKGMFAINQVTGQLTT 850 HSP 6 Score: 72.0182 bits (175), Expect = 7.132e-11 Identity = 282/1272 (22.17%), Postives = 485/1272 (38.13%), Query Frame = 1 Query: 211 IHVAILDAND-PPT-NIQLSNWKVEENILVGSLVGQISVVDEDLDD----SFKCSVKSDSPFNVDA-NFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKII--ILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYES-SYVNYFVVGAYKDQILIFNKTYFIQ----LIDVNEAPQGLTLYP--STVTENIPSGSVIGKFSIL--DSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNE---KDFYIEN--NKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMEN-NELEMTFATITVFEPDF--DDKINCQIISDN--SRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGG----LSIDLEVPISIQDAND-PPTVAGLNF-TMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKF-IDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFV----------TENSNNISLGQLL--LMTDYSNKSLQISKSSIIVLVSN-NIKIQINE-DNSFMLTDPLDYETENNFLISFTLIDKN---SNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVND-GP-------------TAINY-LTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGI--SNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQW----NEKSEIGLLIANLSANDP-EGSQVQ 3780 + + + D ND PP + + VEENI GS + Q++ +D D ++ +D F +D + +L LD E ++++ +++ D SS + + I+V+D+N+ K + E++ G+ + I D D N + + N D L I F L + + + Y+ ++V + +++ IL+V++NP LN +++ + S + ++ D+ IN ++ I + KN + +K L+ ES S+ N V QI T Q L+DVN+ P L P + + EN P +V+ K DS NS IE L F I E++ LD E+ Y L + TD GQ ++ + E+++ + D N+ +L +I EN G I + A D D+ N + Y + VN ++F I++ + D E P Y +T+ D G + T I +L+ N+ + Y ++ EN L T + + D + K++ + N + F + E L + Q+LD E F + I D + T I + V++VN+ A S+ I E+ + + + + D K +++ + N +F + ++ S D E+ KD L+ G LS V +++ D ND PP + T IPS + V V D D I N E+ + + EKF ID ++ + ++ ++D + P T S TV FV E + Q + L+T + SL+ S + N QI++ ++ PLD+E +++ D + L + +LDVN+ K + E P I T A D D D + IVNG + N + E+ + V LD ++++ + I D G PS S + I I++ ND P + + Y +T++T E IN + + ++ F I S I I++ L+ E + V D SG VS+ I + D+N+ + S + E +EIG + + A DP EGS Q Sbjct: 1726 VEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQSSDM-RINITVSDVNDHTPKF----SRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFF------------LNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVDKNGV-LKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF-LSPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLN--PLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGI-VNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYS-----VNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGE--------LGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFA---SKAYFTTIPEDA---PTGTDVLLVNASDADASKNAVIRIIGGNSQFTINPSTGQIIT--SALLDRET---KDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDAD-----------------------IGPNSELHYSLSGRNSEKFHIDPLRGAIMAAGPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQTFMFPENQPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR-KILTVSAMDKDSGPNGQLDYE--IVNGNMENSFSINHATGEIRS-VRPLD---REKVSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQIFSAHVPENSPLGYTVTRVTTSDEDIGINAI------------SRYSIMDASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHD-SGWTVSTDVTIFVTDIND--NAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQ 2906 HSP 7 Score: 67.781 bits (164), Expect = 1.714e-9 Identity = 36/125 (28.80%), Postives = 50/125 (40.00%), Query Frame = 1 Query: 5413 LKVNLCLKSDCVHGICRDDNSCL-------------------------------CLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKN 5691 +KV CVHG C++ SCL CL G+ G C ID+C+ PC+ G C + + GF C+C FTG CE D C ++ +N +C N Sbjct: 3796 VKVESVDHDSCVHGPCQNGGSCLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPG 3920 HSP 8 Score: 63.929 bits (154), Expect = 2.054e-8 Identity = 35/110 (31.82%), Postives = 52/110 (47.27%), Query Frame = 1 Query: 5365 FQCLCGSDRSGRTCEVLKVNLCLKSDC-VHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE--FDHFSCKNCSENFGVC 5676 F C C +G CE+ ++ CL S C G C + SC C G+ G C + I++C+ PC +C++ F C C+ +TG CE ++ C C N G C Sbjct: 3846 FLCKCLPGYAGSWCEI-DIDECLPSPCHSGGTCHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFNCVCKTGYTGKMCESSVNYCECNPCF-NGGSC 3953
BLAST of Protocadherin Fat 4 vs. UniProt/SwissProt
Match: sp|O15943|CADN_DROME (Neural-cadherin OS=Drosophila melanogaster OX=7227 GN=CadN PE=1 SV=2) HSP 1 Score: 101.679 bits (252), Expect = 6.851e-20 Identity = 178/756 (23.54%), Postives = 318/756 (42.06%), Query Frame = 1 Query: 1351 ELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDAN-ERPENLSLSNNQIPENEPIGLLIAIINAQDNDK----NSTLVYTLD--VNE-KDFY---IENNKLLSGTVFDHENRPGYQITITVFDNGDPKL--------NVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNE-PP--------TKLAIDGSREI---IINITE---NIQGYQSIANFITT---DPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND--PPTVAGLNFTMIPSFVEKDFIIGKVNVFDED------NLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFID-EKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFN-WTVDFVTENSNNISLGQLLLMT------DYSNKSLQIS-------KSSIIVLVSNNIKIQINEDNSFMLTDPLDYETE---NNFLISFTLIDK---NSNQSINLK-----VQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIH--SFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVND 3387 ++K N LDYE YNL IRV + G + + ++ + + + D N E P + E EPIG + +NA D D N Y +D NE K+F+ +++ ++ + TVFD E + Y + + D G P +V+K I I + N+NP K Y + + EN +++ T T+T + D +I +I S N + +KN+ + + LDYE +E+ + +D +N+T ++ I V++VN+ PP T++ + R + ++ +T + Q+I F+T DPD N KF+ + ++++ + D + N + + A D G GL +V ++++D ND P G+ F + ++ + D D N IE ++I+ I I + ++ TA +D E+ D IQ +K T + ++ ++DIN+ P F+ + W + + ++ +L ++ ++T D +NK Q + +V NN + S + PLDYE + N F + DK N N ++ V++ D+N+ + +++FE + + F ATDPD S+ I + F I N +T SLD V + V+IL DDG P + + + + ++ND Sbjct: 1250 DIKVNHPLDYESIKEYNLTIRVENNGAQQLASEATVYIMLEDVNDEIPLFTEREQETVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYIVDSPRNEGKEFFEINLQSGEIFTKTVFDREKKGAYALEVEARD-GAPSARPNSNGPNSVTKFIRIGIADKNDNPPYFDKSLYEAEVD-----ENEDIQHTVLTVTAKDHDESSRIRYEITSGN----IGGAFAVKNMTGA-IYVAGALDYETRRRYELRLAASDNLKENYTTVI---IHVKDVNDNPPVFERPTYRTQITEEDDRNLPKRVLQVTATDGDKDRPQNIVYFLTGQGIDPDN------------PANSKFDINRTTGEIFVLKPLDRD-QPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDINDNAPIFPQGVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSPIFEIEPDTGVIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTG-TASIRVKDINDMPPQFTKDEWFTE--VDETDGTALPEMPILTVTVHDEDETNK-FQYKVIDNSGYGADKFTMVRNN-----DGTGSLKIVQPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPHFERANVEVSVFEDTKVGTELEKFKATDPDQGGKSKVSYSIDRSSDRQRQF-----AINQNGSVTIQRSLDREV---VPRHQVKILAIDDGSPPKTATATLTVIVQDIND 1961 HSP 2 Score: 56.6102 bits (135), Expect = 3.137e-6 Identity = 194/920 (21.09%), Postives = 354/920 (38.48%), Query Frame = 1 Query: 1156 IQLIDVNEAPQ-GLTLYPSTVTENIPSGS---VIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYE--KTP-AYNLGIRVT-DYGQENIVTDFEIILEISDANERPENLSLSNNQ---IPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLL-SGTVFDHENRPG-YQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRF-LVQKKSEIKNIFQYDLTI-----NQTLDYEQNNYFEINIEI---------NDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSID--LEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIG----KVNVFDEDNLSTYNQIECSIIKP-----LKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIK---------IQINEDNSFMLTD-----PLDYETENNFLISFTLIDKNSNQ---SINLKVQILDVNEAPSEIKSF--EKNLTMFEKSPPNIHIATFYATDPDY----NQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSL--------SIQSRFYIQIINVNDGPTAINYLTKLTAIKESANIN----TVLAXXXXXXXXXXXXHQCHGSNSYFGISN--SSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNE-PP 3678 + ++ APQ + Y + + EN S I S D + T++ TFN I +K LD+E + P Y+L + T D G T ++ + ++D N+ L + Q + E+ P+G I + A D+D S V++ F +++N ++ + D +N Y+ +T D G+P + T + + N+N E + ++ + ++ EN T+ + D DN RF V + D+T N+ + +++ Y E+N+ D T+ + +F+ +VN+ K + E + + TD D+ N +KYSI+ N + +F+ + ++ FD E + GK + V ++A D G S++ + I D ND P + + V++D IG +V+ DED I S+ P L++F I S + + + +D + +E + G+ + T ++ NN P + +V E N+ +G ++ S+ ++ + + L+ + +Q DN D PLDYE+ + ++ + + + Q + + + DVN+ EI F + T+ E P + A D D NQ++ + + G+ F + + + E+ T V + +E+ R DG PS S+ I I + ND P + + E+ +I TV A E F + N +IY+A LDYET + E + D N ++V I ++DVN+ PP Sbjct: 640 LSIVGGKRAPQFYMPSYEAEIPENQKKDSDIISIKAKSFADREIRYTLKAQGQGAGTFN----IGPTSGIVKLAKELDFEDLRQPHVYSLIVTATEDSG--GFSTSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGSNAEIEYLVSDDHFAVDSNGIIVNNKQLDADNNNAYYEFIVTAKDKGEPPKSGVAT--VRVYTKNKNDE---EPKFSQQVYTPNVDENAGPNTLVTTVVASDKD----------GDNVRFGFVGGGTSSGQFVIEDITGVIRLHNKAISLDKDKY-ELNVTAMDDGSCCVNGDQTIHTSTAVVVVFITDVND--NKPVFKDCSTYYPKVEEGAPNGSPVIKVVATDEDKGVNGQVKYSIVQQPN-QKGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGDPSLEGVCSFTVEITDVNDNPPL--FDRQKYVENVKQDASIGTNILRVSASDED-ADNNGAIVYSLTAPFNPNDLEYFEIQAESGWIVL----KKPLDRETYKLEAMAQDKGYPPLSRTVEVQIDVVDRANNPPVWDHTVYGPIYVKE---NMPVGGKVVSIKASS-GIEGNPTVFYRLMPGSTAQTNKFHTFYLQQRPDNGDTWADIKVNHPLDYESIKEYNLTIRVENNGAQQLASEATVYIMLEDVND---EIPLFTEREQETVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYIVDSPRNEGKEFFE--INLQSGEIFTKT----VFDREKKGAYALEVEAR-DGAPSARPNSNGPNSVTKFIRIGIADKNDNPPYFDKSLYEAEVDENEDIQHTVLTVTAKDHDESSRIRYEITSGNIGGAFAVKNMTGAIYVAGALDYETRRRYELRLAASDNLKENYTTVI-IHVKDVNDNPP 1512
BLAST of Protocadherin Fat 4 vs. TrEMBL
Match: A0A2C9JVA7 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106069582 PE=4 SV=1) HSP 1 Score: 346.665 bits (888), Expect = 6.150e-92 Identity = 477/1967 (24.25%), Postives = 854/1967 (43.42%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSD-SPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEIS--VTDINEAPDKIYVNTTN--EEMILTAN-----ENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIK-HKNELWIKESAELNYE--SSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQ--LITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSR-------------FLVQKKSEIKNIFQYDLTINQTLDYEQNN-YFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVP--ISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLS--TYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIK---------STTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS-NQSINL----KVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYI------TYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSN---SYFGISNSSIYIAKR--LDYETFTKMETIVVC----FDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSD--ILNTNVSLSLEVTIFRENLAQISMEFKDVM-NLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKSLDYETNS--HIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEI-IVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEI--LLHEIRFSIECGDAXXXXXXXXXXXXEDKNDPAIDLVWNGSTIIDLDLTTDGSF-LGNLLVIDEDLNQMHDI--------MIQYPANKYFYIINCCDLMTQNLEYAWTGPLNASFIITDNGIPPMKSIFNISFNFIE------SKGEISATNRLINITDKANTLIGIL-KYSLSNSDDISFILEEVPDNAFSIIKDELWLTKDADQLSF----TNITLKIRSFDQETNLPISKGNLRLEVVGISI---CHFNSNKCHRNATC-KSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLG-DSSRCIDLVNDFQCLCGSDRSGRTCEVLKVN--LCLKSDCVH-GICR--DDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQYCL 5709 C L+FE++ + L++ D PK + V + DAND P I +N +++EN+ VG V ++S D D+ + +SD +PF + N L PLD+E+ V I +D ++ K + + ++ EAP + + N + + T + EN+K GT IG + DPD ++ + + + + CL + ++C++ I + L +FE QS +SV D+ L + + + + ++ P ++ +N+ ++ + ++ENS + LSAID D + + F + + S + N L + +A ++YE + V L +K ++++DVNEAP + L + V+E+ G+ IG F D + I + + L+ N IF I L L + +LDYE +Y + ++VTD G + F+ +E+ + NE P NL LS + E+ I + +++AQD+D T+ +T+ N F + N L+ + D E P + +T D+G P +V+K F I + ++N++P ++ Y + + I E + +I ++PD D+I+ ++ +++ V+ + + + QT+ Y ++ + D + I V + N+PP ++ID ++ + I EN + Y+ + DP D+ + + + + F + LK DYE ++ +R +DSG S + I++ D N+ P+ L+ + I + + + + V D DN T Q ++ + S L + ++ + I++ C +NG + S T AI+ N V+ENS N+ +GQL ++ + +I + ++ S N + E NS LT LDYET I T + +S N +NL K+Q+LDVNE P +I + + E S P + DP+ Q ++ + + V ++ S+ +++N ++ +L + ++N I F + I D G P L++ I ++NVND PT + L I E+ T++ +F + D+D + + C +N F + +S R LDYET V C D S L V+ I++ +VNEPP ++++S NE + + L+A ++A DP+ Q F L + F I S+ K + T++ + V +D L + S ++V E + + K V + P + IGS V + + F N+ S +F+I+ D ++ SLD+E +S I +T + Q L + I VTD +EP I +++ S+ E N + +I++ D + N + C + L F + + + L + N+E + H ++ C D SI + ++I ++D N+P + G L T + + LL D+D+ QM ++Q ++ + T+ L+ ++ + D+G P + +I+ + EI+ N +++ IG++ + + + ++F + + FS IKD +L + S+ +TL+ ++ + + R V+ IS C+ N C NA C + N+L+ +QC CN F G+G C++ID C N + C D ++ FQCLC +G CEV VN C + C + CR DD +C+C GW G C IDDC PC C D F C C TG C+ F CS+N +C N N+ C+ Sbjct: 1339 CGLDFETQRIH-QLQVQVTDSGSPKLTANLAFTVQVQDANDAPVFIG-ANLQLKENMKVGENVTRLSASDADVGQNLTYKNESDINPFTIVGN-QLLLANPLDFESNPTIVVQITVMDSGIPALSAKASFNFEILNVGEAPSSLTLVNLNSAQSAVFTVDQPVIGENTKLGTTIGQLTILDPDFDEDITATVSKDVLKAEKPSCLTVTKQGSRCVSSIILNKAL--DFETQSTYSIGLSVIDKYGLRLDKNFTLQVKDENDPPINILINNEVTSTIKVKENSQGMIVANLSAIDPDKGQTFVFTV----SSSTQFYITDNTLKVSVAAIIDYERIKTLALTLRVTDSGQPPLSLDKNITVEVLDVNEAPTTVVLTRNKVSEDASIGNEIGSFVTSDPDNKEVIRQSFVYELLVNPNNIFGIRNGSLVLA-SAQLDYEMRSSYVITVKVTDNGSPPLSAQFDFSIEVINVNEAPTNLQLSATTVSESAFIDSTVGVLSAQDSDVGQTITFTV-ANSDCFSVNGNLLIVSGMLDFETAPRLLVEVTATDSGTPPKSVAKNFTITVTDANDSPLLM---NYTSVSANQTIDEKTLVNAVVGSIETYDPDNLDRISIELTDASAKNFKLDTAEAICKLIFVESLRSTCTVCSQKVLLAQTVRYIIDSPPLVLEAFAKDKGQLSITNSWKITVLDSNDPPFNISIDATK---LEIPENQRIYK-LGLLTCDDP---DIGQTHLFQVITNYDVFAVDASSVLVILKA---LDYEQQ--PSYQLTLRCVDSGVPSANYSKTFLIAVLDVNEQPSDIKLSNSDISAAAKDGETVAFILVTDPDNAGANTKKQNHTCVLSKDESGSFKVGKDGLSLQILVKPPVNRTSVKIQLNCSDNGVPSMYFVKDFDIFISNTAQVPKAIQLTGNRS-----------VSENSINVEVGQLSIINTLTET--EIPGTYNFIVDSGNFTV---ERNSLRLTTSLDYETSPVLTIIVTALGSDSNNNKVNLSETFKIQVLDVNEPPKQINIYGGG-QVLENSAPGTVVGDLNTVDPELYQTFTYTLISVAVGFDV-TQSLPELLNTFQISG-RTLKIGINNSILDYETTPVFSLVIQTMDSGDPPLALNDTLRIILLNVNDAPTDVKLNNSL--IPENTPAGTLVGVFSVVDQDVNQTYSCVVNNLDSVPFTVESSLNLKVSRAELDYETQKYYILQVTCQDTGSDGSHLKVTKSLMINVTNVNEPPYDLRLSTYSINENNIVDQLVAEIAATDPDSQQTFFTLT---DDSSSFDIHGTGSLVAKKVIDYETKS-KYTISVKAADENGLTSISSFVIQVIDVNEKPTDVKLTQKVVSESAPRGTVIGSIVTQ-DPDRRQTFQYNLTEPPPSTDHFYIVGDQLLVGQTSLDFEFSSVYRISITSTDSGSPAQSL-TVDFDIQVTDANEPPSGINVLSSPISVFETASINTVLSDILVIDVDKNQTH-SCQTVDSKLPFV---------FITSLKGTIQLIVGNVLNFEAQSIYH---VNVSCSDGEFSIYQVITITVKDVNEPPTAITLKGPHF--LPATAIAPYPIDRLLAEDDDIGQMFTFSTSGTNSDLLQVQGGNQLVLV--APIPTELLDQPDPS-ISVIVQVADSGQPVLTFEQSITLTITDIDIEDLKLPEITINNTVVSENGLVGDSIGMIYDQNTTVASSVTFTIASDLSSLFS-IKDNKYLILSKNISSYFGNSAEVTLQAKNSQSQ------QVKTRTIVIVISRSDKCYNNGKTCSENARCIQRNDLS--YQCRCNEDFEGDGYYCQQIDNCKVNVSKPCNQGLCKDGISSFQCLCDVGYTGAYCEVPPVNSDPCKNNTCQNSAACRPTDDKQTYTCVCKPGWTGQRCETDIDDCSESPCPDYQRCVDGTVSFFCQCPDGKTGHRCQ---FYIDACSDN--ICTN----NEICV 3216 HSP 2 Score: 286.574 bits (732), Expect = 1.452e-73 Identity = 394/1622 (24.29%), Postives = 707/1622 (43.59%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDS--PFNVDANFNLFTKAPLDYETQARFEVIIECLDH--ENSSVINKHEISVTDINEAPDKIYVNTTNEEM-----ILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFL---ISQFQL---ELKDNTR----------LDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP-EIIIKDQYGNKTEVFH-----IMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQ-----YDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQ--IECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAP--SEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFN----HSIVKIVNNELLTD---VNSLDVVVSNYITY------FWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTV-LAXXXXXXXXXXXXHQCHGSNSYFGISNSSIY-IAKRLDYETFTKMETIVVCFDQSGL---NVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNK---SLQVLTE----NDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQI--SMEFKDVMNLPENSPIGSKVLEIQI--NFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKSLDYETNSHIMVTVKCF-----QNKLQILKKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLP-LMDNCDLSFNLFISGNFNYEILLHEIR--FSI-----ECGDAXXXXXXXXXXXXEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMI 4722 C LN+E KT++ +++++ D P+ S +F + + + DAND PT+I LS+ KV+ + G+++GQ +V+DED + +K D+ F + + KA + T + V++ D+ + S I++ +NEAP + V N+ + NE+ + +I D + + + F + + + + I G NFE+Q + + TD NN S+ + + IL++ E PTD+ ++ + + ENS + LG +A+DED ++ +SF + + I EL + A+L++E+ + V +F K + + + +VNE P + L +T+ E + +VIG D + N+ + +L+ TF + L +FQL LK R LD+E + L ++VTD G + + +++ DAN+ P + +N Q+ EN +G + ++A D D L Y + + F I N+LL D E+ P + ITV D+G P L+ +F+ EILN E P + + + ++ VF I EN +L T +T+ +PDFD+ I + D +K S + Q + +N+ LD+E + + I + + D + V++ N+PP + I+ I + EN QG +AN DPD+ +++ + +F + L + + DYE K + + +R DSG LS+D + + + D N+ PT L + IG D DN Q + ++ P F I N S L + + + I ++ +NG + S + ++ + ++N P + T V+E++ S +L D +I V+N+ +N N +++ LD+ET L+ T D + + + N + + D N++P S N T+ EK+ N + + DPD + I+ + + F +I K++ E L V S V+++ + Y +E +D GQ LSI + + I +++ ND P I+ I E+ I + L + D + Q + F + SS+ I K LDYE + + C D SG+ N S F I + DVNE P ++K+SN + ++ G +A + DP+ + +N C ++ S + K SLQ+L + ++ ++ SD ++ + IF N AQ+ +++ ++ ENS I +V ++ I +P I GNF + + + L SLDYET+ + + V NK+ + + I V DV+EP K+I + + E +G++ DPE+ ++++ F + +LP L++ +S G N IL +E FS+ + GD +++ L I L + ND D+ N S I + T G+ +G V+D+D+NQ + ++ Sbjct: 903 CSLNYE-KTSSHTVKVIVTDSGSPQESAIFSLTIDVTDANDAPTDIVLSDNKVDFSAKAGTVIGQFNVIDEDSQQTKTFILKDDAGGTFKIMNGTSTLIKADVPLTTSRMYSVLVAVQDNGIPSKSAEQTFYINIVGVNEAPQNLTVTANNKSKQVNTETIAFNESLAINDVVAIIRAEDINLDQKISFSLLNNENNQFQLDKNVSCNVGAVVVCSSNIILAKGVNFEKQDKYNIILVATDSNNQQTSKAISVQILDLGEAPTDIVF---SALSITVVENSVSVVLGSFTAVDEDKSDSHSFTLENNPENIFSISASGELSVTSGAKLDFETKSLYNITVVVTDSTRNLFKKIFNVNVQNVNEPPSSVKLINNTIPEGSEAYTVIGDLFADDPDNNNLVVNSTLKQ-TFEYLLLDDAGGRFQLTQSTLKLTPRGAQCTASWCGLDFETQRIHQLQVQVTDSGSPKLTANLAFTVQVQDANDAPVFIG-ANLQLKENMKVGENVTRLSASDADVGQNLTYKNESDINPFTIVGNQLLLANPLDFESNPTIVVQITVMDSGIPALSAKASFNFEILNVGEAPSSLTLVNLNSAQSAVFTVDQPVIGENTKLGTTIGQLTILDPDFDEDITATVSKD--VLKAEKPSCLTVTKQGSRCVSSIILNKALDFETQSTYSIGLSVIDKYGLRLDKNFTLQVKDENDPPINILINNEVTSTIKVKENSQGM-IVANLSAIDPDKGQTFVFTV------SSSTQFYITDNTLKVSVAAIIDYERI--KTLALTLRVTDSGQPPLSLDKNITVEVLDVNEAPTTVVLTRNKVSEDASIGNEIGSFVTSDPDNKEVIRQSFVYELLVNPNNIFGIRNGS--LVLASAQLDYEMRSSYVITVKVTDNGSPPL-SAQFDFSIEVINVNEAPTNLQLSATT--VSESAFIDSTVGVLSAQDSD------VGQTITFTVANSDCFSVN-GNLLIVSGMLDFETAPRLLVEVTATDSGTPPKSVAKNFTITVTDANDSPLLMNYTSVSANQTIDEKTLVNAVVGSIETYDPD--NLDRISIELTDASAKNFKLDTAEAICKLIFVESLRSTCTVCSQKVLLAQTVRYIIDSPPLVLEAFAKDKGQ--LSITNSWKITVLDSNDPPFNISIDATKLEIPENQRIYKLGLLTCDDPDIGQTHLFQVITNYDVFAVDASSVLVILKALDYEQQPSYQLTLRCVD-SGVPSANYSKTFLIAVLDVNEQPSDIKLSNSDISAAAKDGETVAFILVTDPDNAGAN---TKKQNHTCVLSKDESGSFKVGKDGLSLQILVKPPVNRTSVKIQLNCSDNGVPSMYFVKDFDIFISNTAQVPKAIQLTGNRSVSENS-INVEVGQLSIINTLTETEIPGTYNFIVDSGNFTVERN-SLRLTTSLDYETSPVLTIIVTALGSDSNNNKVNLSETFK--IQVLDVNEPPKQINIYGGGQVLENSAPGTVVGDLNTVDPEL-YQTFTYTLISVAVGFDVTQ---SLPELLNTFQISGRTLKIG-INNSILDYETTPVFSLVIQTMDSGDPPLALNDTLRIILLNVNDAPTDVKLNNSLI--PENTPAGTLVGVFSVVDQDVNQTYSCVV 2476 HSP 3 Score: 209.149 bits (531), Expect = 5.661e-50 Identity = 216/843 (25.62%), Postives = 382/843 (45.31%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDA--NFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEI----SVTDINEAPDKIYVNTTNEEMILTANENSKSGTR-------IGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKD--QILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITF--------------NEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYI-ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEI-----KNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYE-SNIGKDIKVLIRAIDSGGLSIDLE--VPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDN 2532 C N+E K+ + I KD P F I + + D N+P T++ + V ENI+ G + Q++ VDED + K + SD P+ V N L LDYE + + + S ++ ++ V D+NE P + + + N LT + +K + +G + DPD+ D + NS ++C L N + T ++ GFN+E + +I D + V I ++N+D+ P D+ +NDS S+ +++ ENS N ++ L DED+++ Y++ + + I N L+ S+ L+YE+ V+ ++ L KT+ I + D+NEAP + +TV EN P G+++ + S+LD + N+ ++Q TF +F+ + Q + LD+E + ++ IRVTD G ++ + ++D N+ P N+ +S +QI EN+P G +I ++A D DKNS L Y + N + F I E N L+ D+E + Y + + V DNG P ++ + I+++N NE P + T EN+ + + V +PD D + + + F+V K+ I + LT LDYE + + + + + D + ++ + I V + N+ P + ++ +++ EN ++A D D++ +SI++ N F G++ LK S DYE SN+ I + + DSG + + I++ D N+PP+ L + ++G V D DN Sbjct: 49 CAFNYEVKSQYF-VAISVKDDGSPPAVAYFSIEINVTDINEPITDVTFTPDAVAENIVPGKPLLQLTAVDEDRNKQSKFELLSD-PYGVFRINNNTLTATVSLDYEINPTIKYNLRVRGTDLISPVSSVDVNIIFGVKDVNEPPYMLQLTSANA---LTNYQTNKPLAKENVPAIVVGTVSVLDPDKGDNITLSVNSDKFRIIGAKCSVLAGNSSTYCTG-KLVCLAGFNYEEAQMVSVKIKAQDSLLLDVQLDVNITVINMDDPPKDILINDSVSDSIIVSENSKNSTVAVLKTNDEDVDDTYNYFLSGPMANQFRI-DGNILYTTPSSNLDYETYLVSQLIITTVSTNRAGLSMVKTFQIIVSDLNEAPTKVVFSKTTVPENSPEGTLVSELSVLDPD-NTGANTTAVQSFTFELLDDAQGRFYLKNGLLFVKTSTQFCGQSTCSLDFESQSSLSVTIRVTDSGTPSLSLISSQTIAVTDVNDPPSNIQISTSQIKENKPSGAIIGTLSAFDQDKNS-LTYLILNNTEVFSIDERNNLIQLKSLDYEAQSVYFVNVQVTDNGAPSMSSVSSIKIDVMNVNEAPLFL-------GTNFLTAKENSNMGTEVGALLVTDPDNGDSVELTLKTFKDIFIVGNKNIIIKDTPGTNYTASLTTGVILDYETQSEYSVFLSLIDKQGLETVVTLTISVLDENDFPQDILLNNITASTLSVKENT--LSTLAVLTAIDQDKSQTFSFSIISQPGDN----FVVIGNE--LKVSVALDYETSNV---INITLEVTDSGSPPYKKQKMMTINVMDMNEPPSDLKLTNNKVEENSIDGTVVGAFQVSDPDN 864 HSP 4 Score: 166.392 bits (420), Expect = 4.952e-37 Identity = 343/1546 (22.19%), Postives = 637/1546 (41.20%), Query Frame = 1 Query: 214 HVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVD--------ANFNLFTKAP----------LDYETQARFEVIIECLDHENSSV--INKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEI--VKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSY-----VNYFVVGAYKDQILIFNK-------TYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQ-------FQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYT-LDVNEKDFYIENNKLL-----SGTV-------FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP-EIIIKD-------QYGNKTEVFHIM-ENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDG---SREI---IINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFS-----NGGSKLYLKESQFFDYESNIGKDIK--VLIRAIDSGGLSIDLEVPISIQDANDPPT---VAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYN---------------QIECSIIKPLKW-FSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTV--DFVTE--NSNNISLGQLL------LMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQ---SINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTA-----------IKESANINTVLA--------------XXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISND-----QWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQ---LEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMN-LPENSPIGSKVLE-----------IQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQIL-KKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVA 4389 + + D N+ PT + S V EN G+LV ++SV+D D + +V+S + +D N LF K LD+E+Q+ V I D S+ I+ I+VTD+N+ P I ++T+ EN SG IG + D D+N N+T+V + + IQ + ++E QS + + VTD S+S + +KI ++NV+E P L N T+ E ++ +G L D D + S ++ + + I + IK++ NY +S ++Y Y + + +K T I ++D N+ PQ + L T + + + ++L + I++ Q +F+ +ISQ ELK + LDYE + N+ + VTD G + + + D NE P +L L+NN++ EN G ++ D D ++ LD F I +KL+ TV ++E + + + V D+G P+ + + I++ ++N+ P +I++ D + G F+++ E+++ TF I+ D++ + + + + D+ + + Y + ++ N + + +A +I + VNE P L + S+++ I E++ +A D + + I +S+LN N N +F+ N G+ + + N K K +++ A DS + + I D + PT + L+ T++ + V ++G DED +++ E S+ K F ++ +VT +TR + +K ++ +Q N + +K INN S +TV D + ++NN+ + L L+ D + Q+++S+ +K+ LD+ET+ + + D S + ++ VQ+ D N+AP I + NL + E ++ A+D D Q ++ + I + IV N+LL N LD + I V+I D G P+LS ++ F +I+NV + P+++ + +A I E+ + T + +D + C SSI + K LD+ET + + D+ GL + F + ++D N+PP N+ I+N+ + E S+ G+++ANLSA DP+ Q FV + + FYI N+ L S+ + + ++ L + V+D +SL +T+ ++ + N + E++ IG+++ I+ +F+ + N N IF N + VL + LDYE S ++TVK N L + +I V +V+E + ++ T ++ E + + +G + +D ++ + VA Sbjct: 402 QIIVSDLNEAPTKVVFSKTTVPENSPEGTLVSELSVLDPDNTGANTTAVQSFTFELLDDAQGRFYLKNGLLFVKTSTQFCGQSTCSLDFESQSSLSVTIRVTDSGTPSLSLISSQTIAVTDVNDPPSNIQISTSQ------IKENKPSGAIIGTLSAFDQDKNSLTYLILNNTEVFSIDERNNL-------------IQLK-SLDYEAQSVYFVNVQVTDNGAPSMSSVSSIKIDVMNVNEAPLFLGTNFLTAK----ENSNMGTEVGALLVTDPDNGD--SVELTLKTFKDIFIVGNKNIIIKDTPGTNYTASLTTGVILDYETQSEYSVFLSLIDKQGLETVVTLTISVLDENDFPQDILLNNITASTLSVKENTLSTLAVL-----TAIDQDKSQTFSFS---IISQPGDNFVVIGNELKVSVALDYETSNVINITLEVTDSGSPPYKKQKMMTINVMDMNEPPSDLKLTNNKVEENSIDGTVVGAFQVSDPDNKIGFTFSLLDSANGKFRINGDKLVVVSPEQCTVNQQRLCSLNYEKTSSHTVKVIVTDSGSPQESAIFSLTIDVTDANDAPTDIVLSDNKVDFSAKAGTVIGQFNVIDEDSQQTKTF-----------------ILKDDAGGTFKIMNGTSTLIKADVPLTTSRMYS----VLVAVQDNGIPSKSAEQTFYINIVGVNEAPQNLTVTANNKSKQVNTETIAFNESLAINDVVAIIRAEDINLDQKISFSLLN--NENNQFQLDKNVSCNVGAVVVCSSNIILAKGVNFEKQDKYNIILVATDSNNQQTSKAISVQILDLGEAPTDIVFSALSITVVENSVS--VVLGSFTAVDEDKSDSHSFTLENNPENIFSISASGELSVTSGAKLDFETKSLYNITVVVTDSTRNLFKKIFNVNVQNVNEPPSSVKL-----------INNTIPEGSEAYTVIGDLFADDPDNNNLVVNSTLKQTFEYLLLDDAGGRFQLTQST--------LKLTPRGAQCTASWCGLDFETQRIHQLQVQVTDSGSPKLTANLAFTVQVQDANDAPVFIGA---NLQLKENMKVGENVTRLSASDADVGQNLTYKNESDI--------NPFTIVGNQLLL-ANPLDFESNPTIV---VQITVMDSGIPALSAKASFNFEILNVGEAPSSLTLVNLNSAQSAVFTVDQPVIGENTKLGTTIGQLTILDPDFDEDITATVSKDVLKAEKPSCLTVTKQGSRCVSSIILNKALDFETQSTYSIGLSVIDKYGLRLDKNFTLQVKDENDPPINILINNEVTSTIKVKENSQ-GMIVANLSAIDPDKGQT-FVFTVSSSTQ--FYITDNT---LKVSVAAIIDYERIKTLALTLRVTDSGQPPLSLDKNITVEVLDVNEAPTTVVLTRNKVSEDASIGNEIGSFVTSDPDNKEVIRQSFVYELLVNPN-NIFGIRNGSL-----VLASAQLDYEMRSSYVITVKVTDNGSPPLSAQFDFSIEVINVNEAPTNLQLSAT-TVSESAFIDSTVGVLSAQDSDVGQTITFTVA 1840 HSP 5 Score: 139.043 bits (349), Expect = 1.150e-28 Identity = 280/1218 (22.99%), Postives = 507/1218 (41.63%), Query Frame = 1 Query: 103 EYSISCPLNFE-SKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSV--KSDSPFNVDANFNLFTKAP------------LDYETQAR--FEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANE---NSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLN-DSTSNKVLIEENSSNYSLG--ELSAI--DEDIN--ELYSFQIL-------------ILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGL--TLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDK-----NSTLVYT-----LDVNEKDFYIENNKL----------LSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNEPPTKLA---IDGSREIIIN-----ITENIQGYQSIANFITTDPD---------QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKD----FIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDE--KFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLL---LMTDYSNKSLQISKSSII--VLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTA---IKESANINTVLA 3462 E +S L++E S NI+LE+ D P K ++ + ++D N+PP++++L+N KVEEN + G++VG V D D F S+ ++ F ++ + L +P L+YE + +VI+ S I I VTD N+AP +++L+ N+ ++K+GT IG D D F + ++ +N T L I+ ++ R + + + S + I I+ V+E P +L + ++ S +V E + N SL ++ AI EDIN + SF +L + +V + N + K +N+E ++ A +K +Q++D+ EAP + + TV EN S V+G F+ +D + S +L+ N + + +L + +LD+E YN+ + VTD + F + + + NE P ++ L NN IPE +I + A D D NSTL T LD F + + L S D E + +Q+ + V D+G PKL + F +++ ++N+ P I + + EN ++ ++ + D + + SD + F I L + LD+E N + I + D + +A + NV E P+ L ++ ++ + I EN + +I DPD DV+K +CL + + S S + L ++ F+ +S + V ID GL +D + ++D NDPP +N + + K+ I+ ++ D D T+ + + + I+ N V+ A E K + + ++ ++G + S + + + D+N P T T + V+E++ S+G + + +D NK ++ + S + +LV+ N I + + + LDYE ++++I+ + D S + + +++++VNEAP+ ++ T+ E + + + A D D Q +F + N + F+ VN LL LD + VE+ D G P S+ F I + + ND P +NY T ++A I E +N V+ Sbjct: 788 ELKVSVALDYETSNVINITLEV--TDSGSPPYKKQKMMTINVMDMNEPPSDLKLTNNKVEENSIDGTVVGAFQVSDPDNKIGFTFSLLDSANGKFRINGD-KLVVVSPEQCTVNQQRLCSLNYEKTSSHTVKVIVTDSGSPQESAIFSLTIDVTDANDAP---------TDIVLSDNKVDFSAKAGTVIGQFNVIDEDSQQTKTF------ILKDDAGGTFKIMNGTSTL----IKADVPLTTSRMYSVLVAVQDNGIPSKSAEQTFYINIVGVNEAPQNLTVTANNKSKQVNTETIAFNESLAINDVVAIIRAEDINLDQKISFSLLNNENNQFQLDKNVSCNVGAVVVCSSNIILAK---GVNFEKQDKYNIILVATDSNNQQTSKAISVQILDLGEAPTDIVFSALSITVVENSVS-VVLGSFTAVDED-KSDSHSFTLENNPENIFSISASGELSVTSGAKLDFETKSLYNITVVVTDSTRNLFKKIFNV--NVQNVNEPPSSVKLINNTIPEGSEAYTVIGDLFADDPDNNNLVVNSTLKQTFEYLLLDDAGGRFQLTQSTLKLTPRGAQCTASWCGLDFETQRIHQLQVQVTDSGSPKLTANLAFTVQVQDANDAPVFIGAN--------LQLKENMKVGENVTRLSASDADVGQNLTYKNESDINPF---------TIVGNQLLLANPLDFESNPTIVVQITVMDSGIPALSAKASFNFEILNVGEAPSSLTLVNLNSAQSAVFTVDQPVIGENTKLGTTIGQLTILDPDFDEDITATVSKDVLKAEKPSCLTVTK--QGSRCVSSIILNKALDFETQSTYSIGLSV----IDKYGLRLDKNFTLQVKDENDPPINILINNEVTSTIKVKENSQGMIVANLSAIDPDKGQTF-------VFTVSSSTQFYITDNTLKVSVAAIIDYERIKTLALTLRVTDSGQPPL-SLDKNITVEVLDVNEAPTTVVL--TRNKVSEDA---SIGNEIGSFVTSDPDNK--EVIRQSFVYELLVNPNNIFGIRNGSLVLASAQLDYEMRSSYVITVKVTDNGSPPLSAQFDFSIEVINVNEAPTNLQ--LSATTVSESAFIDSTVGVLSAQDSDVGQTITF----TVANSDCFS------VNGNLLIVSGMLDFETA---PRLLVEVTATDSGTPPKSVAKNFTITVTDANDSPLLMNY-TSVSANQTIDEKTLVNAVVG 1922
BLAST of Protocadherin Fat 4 vs. TrEMBL
Match: A0A3M6UXH5 (Uncharacterized protein OS=Pocillopora damicornis OX=46731 GN=pdam_00000057 PE=4 SV=1) HSP 1 Score: 330.872 bits (847), Expect = 6.099e-87 Identity = 481/1979 (24.31%), Postives = 838/1979 (42.34%), Query Frame = 1 Query: 211 IHVAILDANDPPTNIQLSNW---KVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFN-VDANFNLFT--KAPLDYETQARFEVIIECLDHENSSVINKH--EISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR-NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQ---FELG---FNFERQSELYFQISVTDRNNNSLSEI--VKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDI------NELYSFQIL--------ILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELK-----------DNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYT-LDVNEKDFYIENNK-LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP-EIIIKDQYGNKT---EVFHIMENNELEMTFATITVFEPD--------FDDKINCQIISDNSRFLVQKKSEI---KNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGG--LSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNL---STYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQL--------LLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS-NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVS----NYITY--FWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXX----XXXXXXXXXHQCHGSN-SYFGISNSSIYIAKR--LDYETFTKMETIVVCFD--QSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPE---GSQVQFVLNSCKNVECPF-YILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMN-LPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKS-LDYETNSHIMVTVKCFQNKLQILK-KLSTTINVTDVDEPLKEIIVN----ITDS------IQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYF---TNDKNCVTLPLMDNCDLSFNLFISGNFNYEILLHE-IRFSIEC---GDAXXXXXXXXXXXXEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMIQYPANKYFYIINCCDLMTQ---NLEYAWTGP---LNASFIITDNGI----PPMKSIFNISFNFIESKGEISATNRLI--NITDKANTLIG---------------ILKYSLSNSDDISFILEEVPDNAFSIIK--DELWLTKDADQLSFTNITLKIRSF---DQETNLPISKGN--LRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEI----------DECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICR---DDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC--KNCSE 5661 + ++I+D ND P NI L +V EN GSLVGQ+ DED+ + + D+ V N L+ A LD+E Q F V + D + S+ + EIS+ D+NEAP I + N ENS+ GTRIG + +DPD T+S V+ N + + IQ LG ++E Q+ TD + LS + + I + +V+E PT + L+ I+EN + +G S D D + ++++++ ++ DS+ + + S + +S V + Q+ + + I +IDVNE P +TL + V EN P +V+G LD + + T + + F ++ QL++ D +L+YEK +Y + +RVTD G + ++ +++ ++D N+RP + LS+ + EN +G I A D D+ TL ++ L+ + F I++ L D+E ++I V DNG LN +KTF + + N NE P + + G ++ + EN+ T T+ F+ D DD N + + S + I K + L ++ L+YE ++ +I + + D I + + + +VN+ P+ + + G IN EN+ G + + + TD D N +Y+ +N N ++F +K+Y DYE+ I+V R+ D G L+ID + + D N+ PT L+ + K ++G ++V D D++ + C ++ P +N + N+ +V + I+I+C +N + + S + + + D+N +P + + + V EN+ +++G L L++ ++ + S+ + + T LDYE + + ++ D + N + + D N+ P+ + S L++ E S +I + +D D Q H + I + G N S ++N + S + + +Y Y + V + D G P SI + F + + N N+ P +I +L+ + E++ ++TV+ QC N F + N + + LDYET V C + + +VSS+F I+I+DVNE P N+ IS ++ NE G+++ LS +DP+ + L P + L S + + L T+ D + V +D N ++ SL TI ++ K V N + EN+ G+ V +Q + ++F + + L + L+YET + +T+ N L K + ++ V D ++ +II N +TDS I E + + N+ + D + C YF + K+ + L + DL NYE LL ++ S+EC G SI K+ S+++ D N+ D+ NGST+++ ++ G +G L D D+ Q H + + F + N +L+ + +L+Y P L + +TDN + P+K+I N++ + I E RL+ N+T N +G + Y+L N + I + DN+ S D L LS+ + ++ ++ +P N +++ V I C CH +ATC + + + C CN G+ GNG +C+EI DEC+ N C + C D VN + C C S + T + +N C S C++ C + +CLC G+ G C +ID+C+ G C D FIC C+ F G C C K C E Sbjct: 2397 LRISIVDENDAPENITLGGSYSVRVYENA-NGSLVGQLVTSDEDVAQAHTYKLLDDAAGRFVILNDKLYVSLAAKLDFEGQNNFTVKVRSTDSGSPSLSVEQVFEISILDVNEAPVNISLAPAN------VTENSQPGTRIGQLTVSDPDNYGPRGTLQTHSCQVTGSN-------------IGKFTIQSNVLALGGASLDYELTPVTRVQVKCTDNGSPPLSLVRDLSINVNDVNEAPTSISLSSDA-----IDENQPPFLIGFFSTADPDNANQPTNRQTFTYKLMGDTAGFPFVIDGDSLNSTRSLDYEAQRSWNITVQS-------VDSGNPQLSVVTD-FLISVIDVNERPFNITLSNTVVDENCPQDTVVGNLLSLDPDRSQT--HTYTMVNSAGGRFKLAGKQLKVAMSNVDCLKNGGDFCKLNYEKKGSYTVKVRVTDNGSPRLSSEASMVISLNDINDRPNDFRLSSRTVKENATVGTKIGRFTATDEDQFQTLTFSLLNSDGGRFAIDSTGYLFKAKKTDYETSKAHKIVAQVTDNGTVPLNNNKTFIVVVENINEPPINMTLTSTSGQQSFTDNKPRVNENSAANATVGTLQAFDHDEVQSLTFSLDDDANGKFTA-GSHVTCHNNTNIPGVKTMCTALLQVSGDLNYEASHSEDIVVRVTDPSGLFHIQPLQVVILDVNDRPSNITLAGGDTASIN--ENVNG-GYVGDLVATDEDFNQTHRYTWIN----NGGWKFRLRSNKIYASSYANLDYEAKSTYIIRV--RSTDDGSPRLNIDKTFTVKVLDVNERPTDILLSSRNVLENSHKGTVVGNISVLDPDDMGPRGPWQNHSCRVLNPSSTPFKVNGTDNILVVDGDLNYEKLDSYSIDIRCHDNANPPL-SVDKNFKINVIDVNEKP--YDITISNNEVAENTGIVTVGSLDTADPDNELIVVQTFTYTIDAASGSVPFAAVHGL---------LNTTRSLDYEANSTWSLTIKSTDNEGLTTTKNFSIIVKDTNDPPTGV-SASGPLSVNENSQTGEYIGSLTTSDQDVGQTHQYQILNVFAQGH-RNQSSSSNLHNLFSIESPSGRITLQKPGLDYELYANYTVTVNSTDSGFPPYSILASFVVSVNNTNEQPQSI-FLSG-NQVPENSPVDTVVGDLSIYDPDNIHLPLQKFQCSVVNDKPFKVVNHLTLVVSKNTLDYETVDTYTVNVNCTELLPNPFSVSSLFVINIQDVNEAPYNLTISANKLNENGPPGVVVGTLSVHDPDLPSSGRANVSLALKYQTPGPVAFTLNGSRLVTTRKLNFETQ-DSYKVTVVATDSGNPPLNTSLTFTIQVIDVNDPPTAVKLVSNGIYENATAGTIVGVLQATDQDADQSHTFVVTGYGSDWFFVNGSSLRLKGTPLNYETTPVMNITILVLDNGSPPLSYKGNVSVMVLDSNDRPSDIIFNSSLSVTDSTSYQIVIPENSPSGTSLMNLSVVDEDFG-QQHSCELVAGRNYFIISSASKSTSEITLKEGADL----------NYETLLDTLLKVSVECRDDGSPPYSIQKNFSVQVSDVNEAPYDIRLNGSTVVEENVRV-GYAVGYLTCEDPDIGQSHMFTVIGNYSSVFEVNNSYNLVVKDPSHLDYENLHPNLVLTVAIQVTDNPVKGTGAPLKAIGNVTIS-ITDINEAPHDIRLVPANVTVPENVSVGYCLAQIASRNPEKLQTVVYTLLNYQSMLSIEDVCKDNSSSAGHQDDGLPYLIVKSHLSYNDYVVQGYQILIEAEDNGIPPQTFNETVQIHVTKIDPCP--QATCHVDATCSRVDWQN-YTCACNAGYSGNGFNCQEIDECNITCTEVDECIANPC-SNGGTCHDFVNYYNCTCPSGYNNGT-DCTFINFCSSSPCMNDATCNPVLNGYNCLCPCGFTGKHCETNIDECVDPKKCFEGSCTDKNCSFICKCEPQFFGPQCRRMEGECTEKQCGE 4295 HSP 2 Score: 290.812 bits (743), Expect = 9.075e-75 Identity = 415/1745 (23.78%), Postives = 750/1745 (42.98%), Query Frame = 1 Query: 115 SCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSD--SPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKH--EISVTDINEAPDKIYVNTTNEEMILT-----ANENSKSGTRIGVIYCNDPDRNDYLEFYTN-------STDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYK----DQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSN---LNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDND------KNSTLVYTL--DVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP-EIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQII-SDNSRFLVQKKSEIKNIFQYDLTINQ----TLDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGG-----SKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSI--DLEVPISIQDANDPPTVAGLNFTMIPSFVEKDF---------------IIGKVNVFDEDNLSTYN-QIECSIIKPLKWFSILNISQNLEI--VTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIE-------DINNEPATFSF-NWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDP-LDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLD--VVVSNYITY-----FWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAI----NYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSY-FGISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISND-QWNEKSEIGLLIANLSANDPE-GSQVQFVLNSCKNVECPFYILQNSSIFLN-------KSLQVLTENDQLEFEVTVSDILNTNVS----------LSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNF---MPNINCEIFSDGNFFIIVDFKVLLNK-SLDYETNSHIMVTVKCFQ---NKLQILKKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTL---PLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAXXXXXXXXXXXXEDKNDP--AIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMIQYPANKYFYI-INCCDLMTQNLEYAWTGPLNASFIITDNGIPPMKSIFNISFNFIESKGEISAT--NRLINITDKANTLIGILKYSLSNS 4983 SC LN+E + + + + D P S + I D ND P ++QLS+ KV+E+ +L+G+ S DED + + S+K+D F VD+ NL+ DYETQ + + D N S+ + I V ++NEAP I + + ++ ENS GT IG++ D D N L F + + S N++ TKC +R+ +L +FE +E + + VTD +E ++I I++ ++ P ++ L S S V + EN++ +G+L DED+ + +++++L I + ++L++ +A+L++E N F V L + + I ++DVNEAP ++L P+ VTEN G+ IG+ ++ D + T++ S Q+ N Q + LDYE TP + ++ TD G + ++ + ++D NE P ++SLS++ I EN+P LI + D D T Y L D F I+ + L S D+E + + IT+ D+G+P+L+V F I +++ NE P I + + + EN + + +PD ++ S RF + K + D N L+YE+ + + + + D ++ + I + ++N+ P + SR + N T + I F TD DQ + +S+LN S+GG S YL +++ DYE++ K K++ + D+G + + + + +++ N+PP +N T+ + ++ F +G + FD D + + ++ S + N I V T + + D+ + ++ ++ T S I+ D+N+ P+ + + EN N +G L+ + N++ + + + + K ++ + + + LDYE ++ ++I D S N V++LDVNE P++I +N+ E S + DPD + G NHS + + VN D +VV + Y + ++I C D+ P LS+ F I +I+VN+ P I N + + T I +++T E+ T S S F + + + LDYE + + D GL + F I ++D N+PP V S NE S+ G I +L+ +D + G Q+ + NV + Q+SS L+ S ++ + L++E+ + + N + S V++ N S+ F +PENSP+ + V ++ I N + C + +D F ++ ++++K +LDYET V V C + N + IN+ DV+E + ++ + + E +G + + DP++ S V+ + Y T TL L+ L+F S Y++ + + + G+ + S +I++ D NDP A+ LV NG + T G+ +G L D+D +Q H ++ + +F++ + L L Y T +N + ++ DNG PP+ N+S ++S S N +++TD + I I + S S + Sbjct: 2142 SCLLNYEVQKRYV-IRVKTTDDGSPPLSFEKDFGIDIRDVNDKPRDLQLSSNKVKEDAKKNTLIGRFSSRDEDANQTLTYSLKNDDSGRFKVDSLGNLYKANDTDYETQTKHTITAVVTDSGNPSLKMEKLFTIEVLNVNEAPVNINITSQGGQLYFPDGHPQVRENSPLGTVIGMLEALDHDANQTLSFKLDDDAGGKFTLGPSANCQTITNISGVNTKCTIGLRVNGDL--DFELSNEYHVTVRVTDAKGLFTAEQLRISIVDENDAPENITLGGSYS--VRVYENANGSLVGQLVTSDEDVAQAHTYKLLDDAAGRFVILN-DKLYVSLAAKLDFEGQ--NNFTVKVRSTDSGSPSLSVEQVFEISILDVNEAPVNISLAPANVTENSQPGTRIGQLTVSDPDNYGPRGTLQTHSCQVTGSNIGKFTIQSNVLALGGASLDYELTPVTRVQVKCTDNGSPPLSLVRDLSINVNDVNEAPTSISLSSDAIDENQPP-FLIGFFSTADPDNANQPTNRQTFTYKLMGDTAGFPFVIDGDSLNSTRSLDYEAQRSWNITVQSVDSGNPQLSVVTDFLISVIDVNERPFNITLSNTV--------VDENCPQDTVVGNLLSLDPDRSQTHTYTMVNSAGGRFKLAGKQLKVAMSNVDCLKNGGDFCKLNYEKKGSYTVKVRVTDNGSPRLSSEASMVISLNDINDRPNDFRLS-SRTVKENATVGTK----IGRFTATDEDQFQTLTFSLLN----------SDGGRFAIDSTGYLFKAKKTDYETS--KAHKIVAQVTDNGTVPLNNNKTFIVVVENINEPP----INMTLTSTSGQQSFTDNKPRVNENSAANATVGTLQAFDHDEVQSLTFSLDDDANGKFTAGSHVTCHNNTNIPGVKTMCTALLQVSGDLNYEASHSEDIVVRVTDPSGLFHIQPLQVVILDVNDRPSNITLAGGDTASINENVNGGYVGDLVATDEDFNQTHRYT-----WINNGGWKFRLRSNKIYASSYANLDYEAKSTYIIRVRSTDDGSPRLNIDKTFTVKVLDVNERPTDILLSSRNV--LENSHKGTVVGNISVLDPD----------DMGPRGPWQNHSCRVLNPSSTPFKVNGTDNILVVDGDLNYEKLDSYSIDIRCHDNANPPLSVDKNFKINVIDVNEKPYDITISNNEVAENTGIVTVGSLDTADPDNELIVVQTFTYTIDAASGSVPFAAVHGLLNTTRSLDYEANSTWSLTIKSTDNEGLTTTKNFSIIVKDTNDPPTGVSASGPLSVNENSQTGEYIGSLTTSDQDVGQTHQYQI---LNVFAQGHRNQSSSSNLHNLFSIESPSGRITLQKPGLDYELYANYTVTVNSTDSGFPPYSILASFVVSVNNTNEQPQSI-FLSGNQVPENSPVDTVVGDLSIYDPDNIHLPLQKFQCSVVNDKPFKVVNHLTLVVSKNTLDYETVDTYTVNVNCTELLPNPFSVSSLF--VINIQDVNEAPYNLTIS-ANKLNENGPPGVVVGTLSVHDPDLPSSGRANVSLALK-YQTPGPVAFTLNGSRLVTTRKLNFETQDS----YKVTV----VATDSGNPPLNTSLTFTIQVIDVNDPPTAVKLVSNGI----YENATAGTIVGVLQATDQDADQSHTFVVTGYGSDWFFVNGSSLRLKGTPLNYETTPVMNITILVLDNGSPPLSYKGNVSVMVLDSNDRPSDIIFNSSLSVTDSTSYQIVIPENSPSGT 3811 HSP 3 Score: 248.44 bits (633), Expect = 8.343e-62 Identity = 402/1659 (24.23%), Postives = 696/1659 (41.95%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSD--SPFNVDANFNLFTKAPLDYETQARFEVIIECLDHEN--SSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVX----XXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVV-----GAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVN------EKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQII-SDNSRFLV---QKKSEIKNIFQYDLTINQT-LDYEQNNYFEINIEINDMKNFT-AIMKIF-IFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLE--VPISIQDANDPP-----TVAGLNFTMI---PSFVEKD---FIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFI------DIEIQCFNNGHTKIKSTTYS---TA----LAIEDINNEPATFSFNWTVDF-VTENSNNISLGQLL-----LMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINL----KVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPD-YNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKL--------------TAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFG--ISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSV--FQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQ--FVLNSC---------------KNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFK-DVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLN-KSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTD-VDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINI-SAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFN-----------------------LFISGNFNYEILLHE---IRFSIECGDAXXXXXXXXXXXXEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMH 4710 C LN+ES ++ S+ + + D P S ++++ D ND P +QLSN+KV EN + ++VG +S DED S+ D F +D N ++ DYET +++ D+ ++ I V D+NEAP I + T+ +L EN++ GT +G + D D +L F + N C N +L T C T + + ++ N+E S L + VTD +E+ + ++N ++ PT++ L+ S S V ENS N + L DED + +++ + + EI+ ++L+ +A L++ESS V G+ I + T + L DVNE P + L ++V EN +G+VIG+ S+ D + CS+ + N I+ ++ + + +DYE+ ++NL + D G + F I+++ D NE P N++LSN+++ EN+ G+ +A +N D D V ++ + F I+N+ L++ + EN + I D+G P L+ ++T I++++ N+ P+ G + EN++ + T+T + D Q++ S + RF V Q K ++N + + L+YE + I ++ D + + K F I + +VN+ P L + ++ + E+ + I F + D D N + YS+ N + + +F+ + G+ L ++ DYE+ I ++ DSG S+ +E I + + N+ P T G P E +IG + D D T + + L S N + +T + + I D++ + N H ++ T TA ++I D N+ P + + V EN+N +GQL+ + ++ K L + ++L N K+ ++ L LD+E +NNF + D S S+++ ++ ILDVNEAP I N+T E S P I +DPD Y + V G N I +N L SLD ++ V++ C D+G P LS+ I + +VN+ PT+I+ + TA ++AN T ++ G + F I S+ + LDYE V D +S V F I + DVNE P N+ +SN +E ++ NL + DP+ SQ ++NS NV+C L+N F + + + +V V+D + +S + I ++ +F+ + EN+ +G+K+ F + SDG F I L K DYET+ + + N L T I V + ++EP + + T S Q+ NK P +N SA + + ++ +T L D+ + F L +SG+ NYE E +R + G + L + + D ND ++ G ++ +G ++G+L+ DED NQ H Sbjct: 1520 CFLNYES-VSSYSIVVRSVDSGSPSLSINASFNISVNDVNDQPRGLQLSNYKVSENASINTIVGNLSATDEDAGQKLSFSLVDDDNGRFGLDNNGGIYKAKSTDYETSKVHYIVVNVTDNGQPPKAMTRNFSIIVLDVNEAPVSIELTRTS---VL---ENTRLGTVVGSLSAKDNDAVQFLTFKLDEDSAGKFSLQSNVTCQNSSLGGTVCATNLLVNGDI--NYEDTSSLDIIVRVTDEKGLFHTEMFNVTVINENDPPTNVTLDGSDSASV--AENSINVQIDTLLTDDEDQGQRFTYVLSRNPGGNFEIR-GDKLFASRNATLDFESSPSYQIKVISTDNGSPPKSIEV---TLVVNLQDVNEKPTDIQLSNNSVQENRLAGAVIGQLSVRDPDRQQG-HVCSI-TDSANGKVGINNNKITV-GSAGIDYEEASSFNLTVLCRDPGGLTVEKSFVILVQ--DINEAPTNIALSNDKVQENKKGGITVAQLNVTDPDNVKAQVQSVSFSILSSNPNLPFQIQNDALVTTRGLNFENTAQWTFRIKATDDGRPVLSRTQTVTIQVIDVNDAPD-------GLTLSSSSVNENSDSDTLVGTLTALDQDTSQNHTFQLLDSASGRFNVDGNQIKVAVRNTQCLNYGGSSCLLNYEVQKRYVIRVKTTDDGSPPLSFEKDFGIDIRDVNDKPRDLQLSSNK-----VKEDAKKNTLIGRFSSRDEDANQTLTYSLKN--DDSGRFKVDSLGN---LYKANDTDYETQTKHTITAVV--TDSGNPSLKMEKLFTIEVLNVNEAPVNINITSQGGQLYFPDGHPQVRENSPLGTVIGMLEALDHDANQT---LSFKLDDDAGGKFTLGPSANCQTITNISGVNTKCTIGLRVNGDLDFELSNEYHVTVRVTDAKGLFTAEQLRISIVDENDAPENITLGGSYSVRVYENANGSLVGQLVTSDEDVAQAHTYKLLDDAAGRFVIL---NDKLYVS------LAAKLDFEGQNNFTVKVRSTDSGS-PSLSVEQVFEISILDVNEAPVNISLAPANVT--ENSQPGTRIGQLTVSDPDNYGPRGTLQTHSCQVTGS--NIGKFTIQSNVLALGGASLDYELTPVTR---VQVKCTDNGSPPLSLVRDLSINVNDVNEAPTSISLSSDAIDENQPPFLIGFFSTADPDNANQPT---------NRQTFTYKLMGDTAGFPFVIDGDSLNSTRSLDYEAQRSWNITVQSVDSGNPQLSVVTDFLISVIDVNERPFNITLSNTVVDENCPQDTVVGNLLSLDPDRSQTHTYTMVNSAGGRFKLAGKQLKVAMSNVDC----LKNGGDFCKLNYE---KKGSYTVKVRVTDNGSPRLSSEASMVISLNDINDRPNDFRLSSRTVKENATVGTKIGRFTATDEDQFQTLTFSLLNSDGGRFAIDSTGYLFKAKKTDYETSKAHKIVAQVTDNGTVPLNNNKTFIVVVENINEPPINMTLTST-SGQQSFTDNK---------PRVNENSAANATVGTLQAFDHDEVQSLTFSLDDDANGKFTAGSHVTCHNNTNIPGVKTMCTALLQVSGDLNYEASHSEDIVVRVTDPSG---LFHIQPLQVVILDVNDRPSNITLAGGDTASINENVNGGYVGDLVATDEDFNQTH 3090 HSP 4 Score: 203.371 bits (516), Expect = 3.831e-48 Identity = 392/1675 (23.40%), Postives = 694/1675 (41.43%), Query Frame = 1 Query: 124 LNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDANFNLFT--KAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLS--EIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQIL-----ILHTDSVEIKHKNELWIKESAELNYESS--YVNYFVVGAYKDQI---------LIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNN-----------QIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTV-------------------FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPE-IIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFT-AIMKIF-IFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGG-----SKLYLKESQFFDYESNIGKDIKVLIRAIDSGG--LSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIEC---SIIKPLKWFSILNISQNLEIVTTATRFID---EKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTEN-SNNISLGQLL------------LMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQ-------KIIVNGEIFN-----------HSIVKIVNNELLTDVN---SLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAI--KESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGIS---NSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSE--IGLLIANLSANDPEGSQV-----------QFVLNSCKNVECPFYIL--QNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMP-----NINCEIFSDGNFFIIV---DFKVLLNKSLDYETNSHIMVTVKCFQNK---LQILKKLSTTINVTDVDE-PLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNI-----SLYFTNDKNCV--TLPLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAXXXXXXXXXXXXEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMI 4722 L+FES + + +++++ D P S + V + D N+ PT+IQLSN V+EN L G+++GQ+SV D D CS+ + V N N T A +DYE + F + + C D +V I V DINEAP I + +N+++ EN K G + + DPD ++ S S +S L R G NFE ++ F+I TD LS + V I +++V++ P L L+ S+ N E + S+ +G L+A+D+D ++ ++FQ+L + D +IK + ++ + LNY S +NY V Y ++ L F K + I + DVN+ P+ L L + V E+ ++IG+FS D + N T+ SL+ + S L ++T DYE + + VTD G ++ + +E+ + NE P N+++++ Q+ EN P+G +I ++ A D+D N TL + LD + + T+ D E Y +T+ V D L ++ I I++ N+ PE I + Y + EN + +T E D +++ D + V I N Y +++ LD+E N F + + D + + ++ ++F I + +VNE P +++ N+TEN Q I +DPD + L +C + SN G S + DYE + +V ++ D+G LS+ ++ I++ D N+ PT L+ I + F+IG + D DN + + ++ F + +L +TR +D ++ +I +Q ++G+ ++ T +++ D+N P + + TV V EN + +G LL M + + +++ + V +SN ++ D F L+YE + ++ + + D S + ++ + + D+N+ P++ + + T+ E + I F ATD D Q +F + I G +F H IV V + +N + VVV N L GQ S F VN+ A + L A E ++ L CH + + G+ + + ++ L+YE + +V D SGL Q+ I DVN+ P N+ ++ +E G + +L A D + +Q +F L S K + L + S ++ ++V + +D S LN + + +++V E I + ++V+ ENS G+ V I + + P N +C + + + V D ++++ L+YE + ++C N L + K INV DV+E P I N + G+ T +G++ DP+ + ++ + I S+ F + T L + +++L I N E L FSI ++D NDP + +G ++ + T G ++G+L D+D+ Q H I Sbjct: 1834 LDFES-SPSYQIKVISTDNGSPPKSIEVTLVVNLQDVNEKPTDIQLSNNSVQENRLAGAVIGQLSVRDPDRQQGHVCSITDSANGKVGINNNKITVGSAGIDYEEASSFNLTVLCRDPGGLTVEKSFVILVQDINEAPTNIAL--SNDKV----QENKKGGITVAQLNVTDPDN---VKAQVQSVSFSILSSNPNLPFQIQNDALVTTR-----GLNFENTAQWTFRIKATDDGRPVLSRTQTVTIQVIDVNDAPDGLTLSSSSVN----ENSDSDTLVGTLTALDQDTSQNHTFQLLDSASGRFNVDGNQIK----VAVRNTQCLNYGGSSCLLNYEVQKRYVIRVKTTDDGSPPLSFEKDFGIDIRDVNDKPRDLQLSSNKVKEDAKKNTLIGRFSSRDEDANQTLTY-SLKNDDSGRFKVDSLGNLYKANDT--DYETQTKHTITAVVTDSGNPSLKMEKLFTIEVLNVNEAPVNINITSQGGQLYFPDGHPQVRENSPLGTVIGMLEALDHDANQTLSFKLDDDAGGKFTLGPSANCQTITNISGVNTKCTIGLRVNGDLDFELSNEYHVTVRVTD--AKGLFTAEQLRISIVDENDAPENITLGGSYS-----VRVYENANGSLVGQLVTSDE-DVAQAHTYKLLDDAAGRFV-----ILNDKLY-VSLAAKLDFEGQNNFTVKVRSTDSGSPSLSVEQVFEISILDVNEAPVNISL-----APANVTENSQPGTRIGQLTVSDPD--NYGPRGTLQTHSC--QVTGSNIGKFTIQSNVLALGGASLDYE--LTPVTRVQVKCTDNGSPPLSLVRDLSINVNDVNEAPTSISLSSDAIDEN-QPPFLIGFFSTADPDNANQPTNRQTFTYKLMGDTAGFPFVIDGDSLN----STRSLDYEAQRSWNITVQSVDSGNPQLSVVT-DFLISVIDVNERPFNITLSNTV--VDENCPQDTVVGNLLSLDPDRSQTHTYTMVNSAGGRFKLAGKQLKVAMSNVDCLKNGGD--FC---KLNYEKKGSYTVKVRVTDNGSPRLSSEASMVISLNDINDRPNDFRLSSR--TVKENATVGTKIGRFTATDEDQFQTLTFSLLNSDGGRFAIDSTGYLFKAKKTDYETSKAHKIVAQVTDNGTVPLNNNKTFIVVVENINEPPINMTLTSTSGQQS------FTDNKPRVNENSAANATVGTLQAFDHDEVQSLTFSLDDDANGKFTAGSHVTCHNNTNIPGVKTMCTALLQVSGDLNYEASHSEDIVVRVTDPSGLFHIQPLQVVILDVNDRPSNITLAGGDTASINENVNGGYVGDLVATDEDFNQTHRYTWINNGGWKFRLRSNKIYASSYANLDYEAKSTYI---IRVRSTDDG-------SPRLNIDKTFTVKVLDVNERPTDILLSSRNVL---ENSHKGTVVGNISVLDPDDMGPRGPWQNHSCRVLNPSSTPFKVNGTDNILVVDGDLNYEKLDSYSIDIRCHDNANPPLSVDKNFK--INVIDVNEKPYDITISNNEVAENTGIVT---VGSLDTADPDNELIVVQTFTYTIDAASGSVPFAAVHGLLNTTRSLDYEANSTWSLTIKSTDN-EGLTTTKNFSI---------------IVKDTNDPPTGVSASGPLSVNENSQT-GEYIGSLTTSDQDVGQTHQYQI 3401 HSP 5 Score: 202.601 bits (514), Expect = 5.785e-48 Identity = 289/1311 (22.04%), Postives = 550/1311 (41.95%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSV--KSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINEAPDKIYVNTTNEEMILT-----ANENSKSGTRIGVIYCNDPDRNDYLEF---------YTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFN--KTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSN---LNSTIEKCSLQLITFNEIFLISQFQLELKDN-----TRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKN----STLVYTLDVNEKD--FYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIIS--DNSRFLVQKKSEIKNIFQYD-----LTINQT-LDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEK-FEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENS-------------NNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEI---------KSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQK----IIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQ---CHGSNSYFGISNSSIYIAK---RLDYETFTKMETIVVCFD-------QSGLNVSSV--FQIDIEDVNEPPENVKI--SNDQWNEKSEIGLLIANLSANDPEGSQV 3777 C LN+E K + ++++ D P+ S + +++ D ND P + +LS+ V+EN VG+ +G+ + DED + S+ F +D+ LF DYET +++ + D+ + N + V +INE P + + +T+ + T NENS + +G + D D L F +T + V+C N+ + T C +++ +L N+E + VTD + + ++++IL+V++ P+++ L + + I EN + +G+L A DED N+ + + + ++ N+++ A L+YE+ V + D N KT+ ++++DVNE P + L V EN G+V+G S+LD + + S +++ + + F++ DN L+YEK +Y++ IR D + D + + D NE+P ++++SNN++ EN I + + ++ D D T YT+D F + L + D+E + +TI DN L +K F I + ++N+ P + + + + EN++ ++T + D QI++ S + N+F + +T+ + LDYE + + + D ++ + + V N NE P + + G++ + EN + + DPD N + C N+K F+ N + + K + DYE+ + V + S+ I+IQD N+ P ++ + ++G ++V D D L + + S+ LK+ + ++ L +R + + ++ E Q +Y + D N P S +T+ + N N + G ++ + +++ S + ++ ++ +N + + PL+YET I+ ++D S + N+ V +LD N+ PS+I S + + E SP + D D+ Q HS ++ I++ + S + + L LD ++ V + CRDDG P SIQ F +Q+ +VN+ P I L T ++E+ + + ED D H +S F ++NS + K LDYE + V +G + ++ I I D+NE P ++++ +N E +G +A +++ +PE Q Sbjct: 2789 CKLNYEKK-GSYTVKVRVTDNGSPRLSSEASMVISLNDINDRPNDFRLSSRTVKENATVGTKIGRFTATDEDQFQTLTFSLLNSDGGRFAIDSTGYLFKAKKTDYETSKAHKIVAQVTDNGTVPLNNNKTFIVVVENINEPPINMTLTSTSGQQSFTDNKPRVNENSAANATVGTLQAFDHDEVQSLTFSLDDDANGKFTAGSHVTCHNNTNIPGVK--TMCTALLQVSGDL--NYEASHSEDIVVRVTDPSGLFHIQPLQVVILDVNDRPSNITL--AGGDTASINENVNGGYVGDLVATDEDFNQTHRYTWINNGGWKFRLR-SNKIYASSYANLDYEAKSTYIIRVRSTDDGSPRLNIDKTFTVKVLDVNERPTDILLSSRNVLENSHKGTVVGNISVLDPDDMGPRGPWQNHSCRVLNPSS----TPFKVNGTDNILVVDGDLNYEKLDSYSIDIRCHDNANPPLSVDKNFKINVIDVNEKPYDITISNNEVAENTGI-VTVGSLDTADPDNELIVVQTFTYTIDAASGSVPFAAVHGLLNTTRSLDYEANSTWSLTIKSTDN--EGLTTTKNFSIIVKDTNDPPTGV------SASGPLSVNENSQTGEYIGSLTTSDQDVGQTHQYQILNVFAQGHRNQSSSSNLHNLFSIESPSGRITLQKPGLDYELYANYTVTVNSTDSGFPPYSILASFVVSVNNTNEQPQSIFLSGNQ-----VPENSPVDTVVGDLSIYDPD-NIHLPLQKFQCSVVNDKPFKVVNHLTLVVSKNT--LDYETVDTYTVNVNCTELLPNPFSVSSLFVINIQDVNEAPYNLTISANKLNENGPPGVVVGTLSVHDPD-LPSSGRANVSLA--LKYQTPGPVAFTLN----GSRLVTTRKLNFETQ-----------DSYKVTVVATDSGNPPLNTSLTFTIQVIDVNDPPTAVKLVSNGIYENATAGTIVGVLQATDQDADQSHTFVVTGYGSDWFF-VNGSSLRLKGTPLNYETTPVMNITILVLDNGSPPLSYKGNVSVMVLDSNDRPSDIIFNSSLSVTDSTSYQIVIPENSPSGTSLMNLSVVDEDFGQQHSCELVAGRNYFIISSASKSTSEITLKEGADLNYETLLDTLLK-------VSVECRDDGSPPYSIQKNFSVQVSDVNEAPYDIR-LNGSTVVEENVRVGYAVGYLTCEDPDIGQSHMFTVIGNYSSVFEVNNSYNLVVKDPSHLDYENLHPNLVLTVAIQVTDNPVKGTGAPLKAIGNVTISITDINEAPHDIRLVPANVTVPENVSVGYCLAQIASRNPEKLQT 4043 HSP 6 Score: 197.593 bits (501), Expect = 2.322e-46 Identity = 297/1231 (24.13%), Postives = 519/1231 (42.16%), Query Frame = 1 Query: 904 SNKVLIEENSSNYS-LGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKD---QILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTR----------LDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTL-DVNEKDFYIENN-KLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNS-RFLVQKKSEIKN------IFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTEN-SNNISLGQLLLMTDYSNKSLQISKSSIIVLVSN-NIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDI-----QKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGI----SNSSIYIAKRLDYETFTKMETIVVCFDQSG---LNVSSVFQIDIEDVNEPPENVKISND-----------QWNEKSEIGLLIANLSANDPEGSQV-----------QFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFE--------VTVSDILNTNVSLSLEVTIFRENLAQ--ISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSD--GNFFIIVD-FKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLST-TINVTDVDEPLKEI---IVNITDSIQEGLYTNKYIGNIIIKDPE 4359 S I+EN + LG S++D + + +++ I+ E++ + + +YES + + D + +K + I + DVNE P + L +TV EN +++G S D + N SL + F K N L+YE +Y++ +R D G ++ + + ++D N++P L LSN ++ EN I ++ ++A D D L ++L D + F ++NN + D+E + I + V DNG P +++ F I +L+ NE P I + ++EN L +++ + D + ++ D++ +F +Q +N + +L +N ++YE + +I + + D K + V N N+PPT + +DGS ++ EN Q I +T D DQ Y L+ N F G KL+ + D+ES+ IKV+ S SI++ + +++QD N+ PT L+ + +IG+++V D D + CSI +N + + + + + + ++ + C + G ++ S + ++DIN P + + D V EN I++ QL + TD N Q+ S +L SN N+ QI D + + T L++E + D +++ + +Q++DVN+AP + ++ E S + + T A D D +Q H+F + + V+G N V + N + L S ++ + + + DDG P LS + F I I +VND P + + +KE A NT++ F DED + N G S ++Y A DYET TK TI SG L + +F I++ +VNE P N+ I++ Q E S +G +I L A D + +Q +F L N + + N S K L N L+FE V V+D + L ++I EN A I++ + + EN+ GS V ++ + + ++ D G F I+ D V L LD+E ++ V V+ + L I++ DV+E I N+T++ Q G IG + + DP+ Sbjct: 1356 SGSATIQENKPRGTKLGTFSSVDSNNKDQHTYSIVSGGRGKFELRGAD---LYTLVVFDYESLPNQFTLTIRSTDNGSPPMKLDKIFKITVADVNEKPTAIQLSGNTVDENSDVDTILGVLSTTDLD-NGQTYSYSLLDSAGGRFKIQGNFVKVGKSNKNCMLNGGSQCFLNYESVSSYSIVVRSVDSGSPSLSINASFNISVNDVNDQPRGLQLSNYKVSENASINTIVGNLSATDEDAGQKLSFSLVDDDNGRFGLDNNGGIYKAKSTDYETSKVHYIVVNVTDNGQPPKAMTRNFSIIVLDVNEAPVSI-------ELTRTSVLENTRLGTVVGSLSAKDNDAVQFLTFKLDEDSAGKFSLQSNVTCQNSSLGGTVCATNLLVNGDINYEDTSSLDIIVRVTDEKGLFHTEMFNVTVINENDPPTNVTLDGSDS--ASVAENSINVQ-IDTLLTDDEDQGQRFTY----VLSRNPGGNFEIRGDKLFASRNATLDFESSPSYQIKVISTDNGSPPKSIEVTLVVNLQDVNEKPTDIQLSNNSVQENRLAGAVIGQLSVRDPDRQQGH---VCSITDSANGKVGIN-NNKITVGSAGIDYEEASSFNLTVLCRDPGGLTVEK---SFVILVQDINEAPTNIAL--SNDKVQENKKGGITVAQLNV-TDPDNVKAQVQSVSFSILSSNPNLPFQIQND-ALVTTRGLNFENTAQWTFRIKATDDGRPVLSRTQTVTIQVIDVNDAPDGLTLSSSSVN--ENSDSDTLVGTLTALDQDTSQNHTFQLLDSASGRFNVDG---NQIKVAVRNTQCLNYGGSSCLLNYEVQKRYVIRVKTTDDGSPPLSFEKDFGIDIRDVNDKPRDLQLSSN--KVKEDAKKNTLIGRFSSRDEDANQTLTYSLKNDDSGRFKVDSLGNLYKANDTDYETQTK-HTITAVVTDSGNPSLKMEKLFTIEVLNVNEAPVNINITSQGGQLYFPDGHPQVRENSPLGTVIGMLEALDHDANQTLSFKLDDDAGGKFTLGPSANCQ----TITNISGVNTKCTIGLRVNGDLDFELSNEYHVTVRVTDAKGLFTAEQLRISIVDENDAPENITLGGSYSVRVYENA-NGSLVGQL-VTSDEDVAQAHTYKLLDDAAGRFVILNDKLYVSLAAKLDFEGQNNFTVKVRSTDSGSPSLSVEQVFEISILDVNEAPVNISLAPANVTENSQPGT----RIGQLTVSDPD 2539 HSP 7 Score: 138.272 bits (347), Expect = 1.841e-28 Identity = 301/1357 (22.18%), Postives = 550/1357 (40.53%), Query Frame = 1 Query: 1174 NEAPQGLTLYPS-TVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRL---DYEKTP-AYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTL-DVNEKDFYIENNKLLSG-------------TVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISD-NSRFLVQKKSEIKNIFQYDLTINQTLDYEQN--NYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITE--NIQGYQSIAN-----FITTDPDQNDVIKYSILNCLNCNEKFEFSNGGS--KLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEK--DFIIGKVNVFDEDNLSTYNQIECS------IIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENS-NNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCH---GSNSYFGISNSSIYIAKR-------------LDYETFTKMETIVVCFDQSG--LNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQN--SSIFLNKSLQVLTENDQLEFEV----TVSDIL--NTNVSLSLE----VTIFRENLAQI---------SMEFKDVM-NLPENSPIGS-----KVLEIQINFLSNFM------------PNINCEIF---SDGNFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNK---YIGNIIIKDPEI---------NISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAXXXXXXXXXXXXEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDED------LNQMHDIMIQYPANKYFYI-INCCDLMTQNLEYAWTGPLNASFIITDNGIPPMKSIFNISFN 4878 N+ P + L S T+ EN P G+ +G FS +DSN ++ + +++ +F+L D L DYE P + L IR TD G + D + ++D NE+P + LS N + EN + ++ +++ D D T Y+L D F I+ N + G ++E+ Y I + D+G P L+++ +F+I + + N+ P G + + + EN + ++ + D K++ ++ D N RF + I ++ DYE + +Y +N+ N I V +VNE P ++I+ +R ++ T + G S + F+T D++ K+S+ + + C S GG+ L + +YE DI ++R D GL +++ + NDPPT L+ + S E + I + DED + + I+ K F+ N + + E I++ +NG + KS + + ++D+N +P + + V EN +GQL + + S + S N K+ IN + + + +DYE ++F ++ D +S + VQ D+NEAP+ I N + E I +A TDPD + +Q + + N ++ + N+ L L+ + T+ I DDG+P LS IQ+I+VND P + + +++ E+++ +T++ D+DT H ++ F + + I +A R L+YE + V D L+ F IDI DVN+ P ++++S+++ E ++ LI S+ D + +Q Y L+N S F SL L + + ++E T++ ++ + N SL +E + + N A + + F D + ENSP+G+ + L+ N +F P+ NC+ S N + +V N LD+E ++ VTV+ K + I++ D ++ + I + + S++ +Y N +G ++ D ++ + +A + V N LY + L+ L G N+ + + S + G S+ + I + D N+ +++ + + + + G+ +G L V D D Q H + F I N L +L+Y T TDNG PP+ + ++S N Sbjct: 1347 NDPPSQIVLSGSATIQENKPRGTKLGTFSSVDSN---NKDQHTYSIVSGGR----GKFELRGADLYTLVVFDYESLPNQFTLTIRSTDNGSPPMKLDKIFKITVADVNEKPTAIQLSGNTVDENSDVDTILGVLSTTDLDNGQTYSYSLLDSAGGRFKIQGNFVKVGKSNKNCMLNGGSQCFLNYESVSSYSIVVRSVDSGSPSLSINASFNISVNDVNDQPR-------GLQLSNYKVSENASINTIVGNLSATDEDAGQKLSFSLVDDDNGRFGLDNNGGIYKA--------KSTDYETSKVHYIVVNVTDNGQPPKAMTRNFSIIVLDVNEAP--VSIELTRTSVLENTRLGTVVGSLSAKDNDAVQFLTFKLDEDSAGKFSLQSNVTCQNS---SLGGTVCATNLLVNGDINYEDTSSLDI--IVRVTDEKGLFHTEMFNVTVINENDPPTNVTLDGSDSASVAENSINVQIDTLLTDDEDQGQRFTYVLSRNPGGNFEIRGDKLFASRNATLDFE---------SSPSYQIKVISTDNG-SPPKSIEVTLVVNLQDVNEKPTDIQL--SNNSVQENRLAGAVIGQLSVRDPDRQQGHVCS-----ITDSANGKVGINNNKITVGSAGIDYEEASSFNLTVLCRDPGGLTVEKSFVILVQ--DINEAPTNIA--LSNDKVQENKKGGITVAQLNVTDPDNVKAQ---VQSVSFSILSSNPNLPFQIQNDALVTTRGLNFENTAQWTF---RIKATDDGRPVLSRTQTVTIQVIDVNDAPDGLTLSS--SSVNENSDSDTLVGTLTALDQDTSQNHTFQLLDSASGRFNVDGNQIKVAVRNTQCLNYGGSSCLLNYEVQKRYVIRVKTTDDGSPPLSFEKDFGIDIRDVNDKPRDLQLSSNKVKEDAKKNTLIGRFSSRDEDANQTLT------------YSLKNDDSGRFKVDSLGNLYKANDTDYETQTKHTITAVVTDSGNPSLKMEKLFTIEVLNVNEAPVNINITSQGGQLYFPDGHPQVRENSPLGTVIGMLEALDHDANQTLSFKLDDDAGGKFTLGPSANCQTITNISGVNTKCTIGLRV--NGDLDFELSNEYHVTVRVTDAK-GLFTAEQLRISIVDENDAPENITLGGSYSVR--VYENANGSLVGQLVTSDEDVAQAHTYKLLDDAAGRFVILNDKLYVS---------------LAAKLDFEGQNNFTVKVR----STDSGSPSLSVEQVFEISILDVNEAPVNISLAPANVTEN--SQPGTRIGQLTVSDPDNYGPRGTLQTHSCQVTGSNIGKFTIQSNVLALGGASLDYELTPVTRVQVKCTDNGSPPLSLVRDLSIN 2607 HSP 8 Score: 135.576 bits (340), Expect = 1.249e-27 Identity = 196/862 (22.74%), Postives = 359/862 (41.65%), Query Frame = 1 Query: 124 LNFESKTNNISLEILAKDLDVP--KNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSV--KSDSPFNVDANF------------NLFTKAPLDYETQARFEVIIECLDHENSSV-INKH-EISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNN--NSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSV-EIKHKNELWIKES--------------AELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKC------SLQLITF------NEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTL-DVNEKDFYIENNKLLSGTV-FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESN-------IGKDIKVLIRAIDSGG--LSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDED 2529 ++ES N +L I + D P K K+F I VA D N+ PT IQLS V+EN V +++G +S D D ++ S+ + F + NF N ++ L+YE+ + + +++ +D + S+ IN ISV D+N+ P + ++ +EN+ T +G + D D L F + D N Y T+ +E Y ++VTD +++ II+L+V+E P ++L ++ ++E +G LSA D D + +F+ L DS + ++ + + S ++NYE + +V ++ L + + + +I+ N+ P +TL S S+ ++++N I+ Q T+ F I +L N LD+E +P+Y + + TD G + +++ + D NE+P ++ LSNN + EN G +I ++ +D D+ V ++ D I NNK+ G+ D+E + +T+ D G L V K+F I + + NE P I + EN + +T A + V +P D + Q+ S + L + I L + L++E + I+ D + + I V +VN+ P L + S ++ EN + D D + + +L+ + + +F K+ ++ +Q +Y + + K + ++ D G LS + + I I+D ND P L+ + +K+ +IG+ + DED Sbjct: 1410 FDYESLPNQFTLTIRSTDNGSPPMKLDKIFKITVA--DVNEKPTAIQLSGNTVDENSDVDTILGVLSTTDLDNGQTYSYSLLDSAGGRFKIQGNFVKVGKSNKNCMLNGGSQCFLNYESVSSYSIVVRSVDSGSPSLSINASFNISVNDVNDQPRGLQLSN------YKVSENASINTIVGNLSATDEDAGQKLSF--SLVDDDNGRFGLDNNGGIYKAKSTD----------YETSKVHYIVVNVTDNGQPPKAMTRNFSIIVLDVNEAPVSIELTRTS----VLENTRLGTVVGSLSAKDNDAVQFLTFK---LDEDSAGKFSLQSNVTCQNSSLGGTVCATNLLVNGDINYEDTSSLDIIVRVTDEKGLFHTEMFNVTVINENDPPTNVTLDGSD------------SASVAENSINVQIDTLLTDDEDQGQRFTYVLSRNPGGNFEIRGDKLFASRNATLDFESSPSYQIKVISTDNGSPPKSIEVTLVVNLQDVNEKPTDIQLSNNSVQENRLAGAVIGQLSVRDPDRQQGHVCSITDSANGKVGINNNKITVGSAGIDYEEASSFNLTVLCRDPGG--LTVEKSFVILVQDINEAPTNIALSN-------DKVQENKKGGITVAQLNVTDP---DNVKAQVQSVSFSILSSNPNLPFQIQNDALVTTRGLNFENTAQWTFRIKATDDGRPVLSRTQTVTIQVIDVNDAPDGLTLSSS-----SVNENSDSDTLVGTLTALDQDTSQNHTFQLLD--SASGRFNVDGNQIKVAVRNTQCLNYGGSSCLLNYEVQKRYVIRVKTTDDGSPPLSFEKDFGIDIRDVNDKPRDLQLSSNKVKEDAKKNTLIGRFSSRDED 2213
BLAST of Protocadherin Fat 4 vs. TrEMBL
Match: K1Q5S6 (Protocadherin Fat 4 OS=Crassostrea gigas OX=29159 GN=CGI_10005202 PE=4 SV=1) HSP 1 Score: 259.225 bits (661), Expect = 3.970e-65 Identity = 349/1477 (23.63%), Postives = 639/1477 (43.26%), Query Frame = 1 Query: 115 SCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHEN--SSVINKHEISVTDINEAPDKIYVNTTNEEMILTAN-----ENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNE--LWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSR-FLVQKKSEI-KNIFQY-------------DLTINQTLDYE-QNNYFEINIEINDMKNFTAIMKIFIF-VENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIE---CSIIK-PLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVN-GEIFNHSIVKIV---NNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCH--------------GSNSYFGISNSSIYIAK-RLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEV--TVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDF-----KVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAI 4377 SC L++E+ N+ + + +D P + + + ++D NDPP ++ LS + E+ VG L+G I V + + D S+ D V + K LD+ETQ+ + + I D + V +I+V D+NEAP + + ++N N ENS IG I D D D + T + +S N QC+ C ++R + F+ E L +++ DR +S + + I + ++ P D+ + T ++E S N + L+A D D + F+ H + L++ +S + + Y VVG I E P + N P+ ++ KFS+ D + ++F ++Q QL LDYE+ Y + + V D G ++ I + I+DAN+ P +L LS +I EN IG ++ ++A+D D+ L ++L + + +E ++ D E T D+G P +VSK+F + + + N+ P ++ G + F I E+ + + T+ +PD +DK++ ++ D F++ S+ QY ++ + L++E ++ + ++I D KN T++++ + F V+N N+ P ++IDG + I EN + I TTD D+ D Y +++ F G+KL + DYE +V I++ D GGLS + N+ P LN + + I+G V V D DN+ + ++ CS+ L F+I + S NL++V+ +D + I I C ++G ++ + + +L I++I P V EN+++ ++G+ + +N+ ++ ++ + L+ + E + T D+E + + ++ + SN ++I +VNEAP I + E S I D + NQI+++ + I + N SI K V +N LT + F V + D G P LS I + +VND P I +L+ + + E++ T + + DED D+H C G N Y + ++ + K LD+E ++ V D + S+ QI I DVNEPP ++ ISN E E G +A LS DP+ +Q +FV S + E ++ LQ + + EN LE + T S I + + + + N I + + + +PE+ +GS + +I ++ ++ C++ F ++ +++L+ LDYETNS ++ +KC + + K++S I + +++E + ++ + ++ T IG + + DP++ + I Sbjct: 1705 SCLLDYET-MNSFDVVVTTQDSGSPSLNLTVSLTIQVVDVNDPPHHLVLSVTALPEDTRVGELLGNIEVNNAEPDQEVMYSISEDQDVFVVEGNKVVLKNALDFETQSMYNLTITAQDDGTPPAQVSKTFQITVIDVNEAPFGLLITSSNMNTKFPVNQPIILENSVRNVLIGQIVVQDYDTEDAVTMRTTNMQISIVNQQCVPTVK-MVHCTADLRAA--VVFDHETTPSLSAELTAVDRQGSSATVQFNLTIQDTNDPPIDINAGEDT---YTVDEGSRNIKITTLTASDVD-SAYLDFETKPQHVLKIRATDNGSPPLYVDKSFTVRIPEDSLPYTVVG-----------------ILTGEDPDNV---------NKPTQTL--KFSLADPD---------------EKMFAVNQTQLMFISGA-LDYERVQQYTVEVMVVDNGDPSLSASTNIAIHITDANDPPTDLKLSAMEINENCEIGTVVGTLSAEDVDRGQNLTFSLS-DTSNLVVEGEQVKVTGNIDFEQIALLTFKATATDDGHPPRSVSKSFSVAVRDMND-PPTSLQFVTGTLVKDFMIPESMAMGGSIGTLEGVDPDGEDKLSFNMLEDGGGVFMLSNSSKCGPTTVQYQNAKSFIGTKCSIEVRLASVLNFESESPEMTLKVQIKD-KNGTSLIEKWTFNVKNTNDAPIDISIDGRQ---TEIPENEPSF-IIGALQTTDEDEGDTFTYHVISHWEL-----FRIRGNKLEVASP--LDYEEK--SQYRVTIKSTDDGGLSFSKSFIFKVLSLNEKPNNISLNPKEVSNNAAVGDIVGLVTVVDPDNVDPDSPVQTHNCSVGGDGLGVFTIDHGSNNLKVVSAIP--VDRTDMTIIITCKDDGSPPLE-YSQNISLIIKEIVTIPKEVKL-INQKPVPENTDSFTVGKFQVFNMLTNEPVE-NEMYLYFLLDYGAPFTL-EGDLLKTTKAFDFEMQQSVKVAVNAMAFGSNLHGEFTIEIENVNEAPIGIGI-YGGGILKENSAEGTIIGDINTRDQEKNQIYTYTLDAIYPGLSDPGNASIYKDVFKLHNRTLTVGQPGKFLDFEKFPVFSVLVTSTDSGLPPLSYAGVIRIVLQDVNDQPGNI-FLSN-SQVYENSLAGTEVGNLTVSDEDKKDLHSCSVATTGVPFKIKFEVGDNPYVELDGTNTVVTKTELDFEVLSQFLITVTAVDSDKGSNSTKIQIKILDVNEPPRDIYISNLLVKENLEPGTELAKLSTVDPDNNQ-EFVY-SIPDTE--YFELQGDELLSGTRMMDYEENSSLELVINSTDSGIPPHTIQRTFVIDVEDVNEPLIDIVLEAIAPVPEDLSLGSVLSKILVDDPEETQQHV-CQVLPSLVPFSVITSGNGTKELILSGVLDYETNSEFVLRIKCSDGEFDLTKEIS--IKIKNINEEPYGMTLSGSHTVLANGTTGYSIGEVTVLDPDVEQTHI 3097 HSP 2 Score: 216.083 bits (549), Expect = 4.486e-52 Identity = 215/830 (25.90%), Postives = 374/830 (45.06%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSP--FNVDANFNLFTKAPLDYETQARFEVIIECLDHENSS----VINKHEISVTDINEAPDKIYVNTTNEEMILTAN-----ENSKSGTRIGVIYCNDPDRNDYLEFYTNSTD-----VXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHK---NELWIKESAELNYE--SSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTR------------------LDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFD-NGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQ-----YDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQ--DANDPPTVAGLN 2460 C LN E + + + ++ +D P F + V + D ND P ++ + + E + G+ + + +DED D F+ + DS F+V N +L + D+E A E I+ +N S V++ +V D+NEAP +++ ++N + + EN+K+ +G I D D+ D LE N D + N C + T CL + + F F+ E + E+ +SV+D + + + + ILNV++ P+D+ LN+++ + + EN +N + LSA D+D+++ +SF +L DS + K + +L E A L++E ++Y V + K +++ D NEAP+ + L + V E G VIG S D + N + + QF L D+ R D+EK ++ ++VTD G + + LE+ D N+ P++L L I EN P G +I + A D D TL +TL +N D ++ +N L + T D+E +P Y I++ D GDPK V T +++L+ NE P I K H+ E+ ++ T+TV + D ++++ + + F++ S Q L + LDYE + + + + D A I V++VNEPPT + ++G +++ E Q ++A D D N +S L + F G+KL +K S ++E+ ++ I D+G + + IS+Q D N+PP L+ Sbjct: 470 CVLNMEEQQVHF-VTLMGQDDYSPPGISYFNLAVTLTDVNDKPESVTMEPDSIPEEVEPGTPLTALKTIDEDRDQEFQYRLIEDSSGLFSV-VNGSLISSVKFDFEEDAGKEFQIKIQSDDNGSPSYRVVSTIVFTVGDVNEAPYDLHLTSSNAPIQFPEDKPKVKENAKAAI-VGTIVVKDQDKGDNLEI--NLADDLGGRLVIMNKMCSQVQGINTYCLGTL-VTFG-SFDHETEGEVNISVSVSDNGSLQTTAVWTMEILNVNDAPSDILLNEASVKEGTVVENHNNALIAVLSAADDDVDDTHSFHLL----DSADGKFRIEGRQLMTSELANLDFENINTYTIRIVAKDSGKPAMSCEKFVTVRVQDENEAPRNIRLSANKVPELSEPGFVIGTLSTEDPD---------------NSVREVQQFVYSLDDDIRGQVEVKKSMLQCDGQPCKFDFEKESQVSVKVKVTDSGSPPLTFVETLTLEVIDQNDPPQDLRLVGESIVENSPPGTIIGKLTAFDEDVGQTLSFTL-LNYTDVFVLKGDNSLATITSLDYEVQPVYAISVKCSDERGDPKF-VDSTVTVKVLDVNEPPSFI-------KVTEIHVPEDRKVGEAIGTVTVEDADLKEQLSFTVTRGYTDFMITNTSCFTESGQGIRCVGSLALKHPLDYEAVSTLPLAVSVQDSGGLAATHSQMISVDDVNEPPTDILLNGKSLTSLSVYEMTQN-DTLAELSAHDTDLNQSHIFS----LQSGDPVNFEIIGNKLRVKSSAVLNFETQ--NVYRLAINVTDNGLPPLSMVKAISVQIIDVNEPPETLSLD 1257 HSP 3 Score: 209.92 bits (533), Expect = 3.048e-50 Identity = 296/1319 (22.44%), Postives = 560/1319 (42.46%), Query Frame = 1 Query: 115 SCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKS--DSPFNV--DANFNLFTKAPLDYETQARFEVIIECLDHENSS--VINKHEISVTDINEAPDKIYVNTTNEEMILT-------ANENSKSGTRIGVIYC--NDPDRNDYLEF-YTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNT---------RLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP--EIIIKDQYGNKTEVFH--IMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQ--YDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPP--------TKLAIDGSREI-----------------------IINITENIQGYQSI---ANFITTDPDQNDVIKYSILNCL------NCNE-----KFEFSNGGSKLY-LKESQF------FDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSF---NWTVDFVTENSNNI--SLGQLLLMTDYSNKSLQ---ISKSSIIVLVSNNIK-----IQINEDNSFM---------LTDPLDYETEN-NFLISFTLIDKNSNQSI-NLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKL----TAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGI-------SNSSIYIAKRLDYETFTKMETIVVCFDQSG--LNVSSVFQIDIEDVNEPPENVKISNDQ 3705 C LN+E +++ ++ +L D VP S +F + V + D ND PTN+ LS K++ + + G+L+GQ+SV+DED D S S+ S D F V + + T PL E+ ++++++ +D V + +++V I +AP + V+ T+EE + + EN SG+ IG + N D+N + + + + TKC +++Q L +FE+Q+ + V +++ L E+ +++I N +E P D++ +S + ++ENS + D D + +SF +L + + +L + + A +++E S +V L K + +++ DVNE P ++L + V E G+VIG+ + D +L+ T + + + Q+ ++ + LDYE ++++ + D G ++ + +++ D N+ P +L LS +PE+ +G L+ I + + + ++Y++ ++ F +E NK++ D E + Y +TIT D+G P VSKTF I +++ NE P +I K V I+EN+ + I V + D +D + + + + Q+ + DL D+E + D + +A ++ + +++ N+PP T +GSR I ++ I G + +F P+ D + Y+++ L N N+ KF ++ K++ + ++Q DYE ++V++ +D+G LS + I I DANDPPT L+ I E ++G ++ D D ++ L S L + VT F + + ++GH +S + S ++A+ D+N+ P + F DF+ S + S+G L + L + + ++SN+ K +Q SF+ L L++E+E+ + + DKN I + + N+AP +I S + T ++ P+ I TD D ++ +I + E+F +I N+L + LD + + V I DDG LS F +++++N+ P I+ K A+ + + TV+ ++ + H C G+ +N + A +D T M I+ C D L S + I+++ P+ VK+ N + Sbjct: 1275 GCSLNYE-RSSMYNVTVLVSDNGVPPQSSVFSLTVQLTDVNDRPTNMTLSGHKIQSDAVKGTLIGQLSVMDEDADQSHTFSLVSGGDGQFLVSNEGKVSKSTDQPL--ESGNVYDIVVQAVDSGQPQLKVTSTFQVTVLGI-KAP--VSVDFTSEEGVGSFPVNHPVVMENLASGSVIGYLVGVNNGMDQNLVFSLEIKEGENPFRLENVSCSSADDLTKCTVGVKMQNIL--DFEKQTSVSVTAIVENKDGGKLVEMFEVVIENENEAPKDIR---PSSTDLSVQENSKGQMVTMFLVSDPDAGDTHSFTLLGNPGQKFSLSTQGQLSVAKDAVIDFEKSPAIDIMVQVTDRGGLSLKKNFTVRVEDVNEKPTQISLSQNKVKEMSEPGTVIGQLTTEDEDLDQTHTYTLMDNAGGRVLLNGTTLQVAIRGDNCDERGGSSCLLDYETMNSFDVVVTTQDSGSPSLNLTVSLTIQVVDVNDPPHHLVLSVTALPEDTRVGELLGNIEVNNAEPDQEVMYSISEDQDVFVVEGNKVVLKNALDFETQSMYNLTITAQDDGTPPAQVSKTFQITVIDVNEAPFGLLITSSNMNTKFPVNQPIILENSVRNVLIGQIVVQDYDTEDAVTMRTTNMQISIVNQQCVPTVKMVHCTADLRAAVVFDHETTPSLSAELTAVDRQGSSATVQFNLTIQDTNDPPIDINAGEDTYTVDEGSRNIKITTLTASDVDSAYLDFETKPQHVLKIRATDNGSPPLYVDKSFTVRIPE--DSLPYTVVGILTGEDPDNVNKPTQTLKFSLADPDEKMFAVNQTQLMFISGALDYERVQQYTVEVMV--VDNGDPSLSASTNIAIHITDANDPPTDLKLSAMEINENCEIGTVVGTLSAEDVDRGQ-------NLTFSLSDTSNLVVEGEQVKVTGNIDFEQIALLTFKATATDDGHPP-RSVSKSFSVAVRDMNDPPTSLQFVTGTLVKDFMIPESMAMGGSIGTLEGVDPDGEDKLSFNMLEDGGGVFMLSNSSKCGPTTVQYQNAKSFIGTKCSIEVRLASVLNFESESPEMTLKVQIKDKNGTSLIEKWTFNVKNTNDAPIDI-SIDGRQTEIPENEPSFIIGALQTTDEDEGDTFTY---HVISHWELF-----RIRGNKLEV-ASPLDY---EEKSQYRVTIKSTDDG--GLSFSKSFIFKVLSLNEKPNNISLNPKEVSNNAAVGDIVGLVTVVDPDNVDPDSPVQTHNCSVGGDGLGVFTIDHGSNNLKVVSAIPVDR---TDMTIIITCKDDGSPPLEYSQNISLIIKEIVTIPKEVKLINQK 2552 HSP 4 Score: 186.037 bits (471), Expect = 5.445e-43 Identity = 226/866 (26.10%), Postives = 385/866 (44.46%), Query Frame = 1 Query: 3346 IQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGIS---NSSIY---------------IAKRLDYETFTKMETIVVCFDQS--GLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSC--KNVECPFYIL----QNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLE------IQINFLSNFMPNINCE-IFS--DGNFFIIVDFKVLLN-KSLDYETNSHIMVTVKCFQNKLQILKKLST-TINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEILLH---------EIRFSIECGDAXXXXXXXXXXXXEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMIQYPANKYFYIINCCDLMTQNLEYAWTGPL------------NASFIITDNGIPPMKSIFNISFN--------FIESKGEISATNRLINITDKANTLIGILKYSLSNS--DDISFILEEVPDNAFSIIKDE--LWLTKDADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNF--CLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCL----------CLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK--NCSENFGVCLNLKN 5691 + F I+I NVN+ P + +KE++ T++ D++ + I+ Y G+S N+SIY K LD+E F +V D L+ + V +I ++DVN+ P N+ +SN Q E S G + NL+ +D + L+SC PF I N + L+ + V+T+ +L+FEV +S L T ++ + N +I ++ DV P + I + +++ ++ LS P+ N E ++S D +F + ++L + +DYE NS + + + + + T I+V DV+EPL +I++ + E L + I++ DPE T C LP + + F++ SGN E++L E I+C D ++K++SIK+++ N+ + +GS + + TT G +G + V+D D+ Q H I I+ P + + I + +N + TGP+ + + TDNG PP+ FN +F+ F IS N+ + ++G L YS++ + +DI F L P + FSI KD L L ++ ++ T++ + + + ET + N+ + + ++ C N KC NA C + + C C GF G+G SC+ ID C N C + + CI+ VN + C+C + G C++ ++ + C C++ CL C GW+G C S DDCIG C+G G C D + C+C + TG CE+ C+ N N VC+ L + Sbjct: 2627 LHGEFTIEIENVNEAPIG-IGIYGGGILKENSAEGTIIGDINTRDQEKNQIYTYTLDAIYPGLSDPGNASIYKDVFKLHNRTLTVGQPGKFLDFEKFPVFSVLVTSTDSGLPPLSYAGVIRIVLQDVNDQPGNIFLSNSQVYENSLAGTEVGNLTVSDEDKKD----LHSCSVATTGVPFKIKFEVGDNPYVELDGTNTVVTKT-ELDFEV-LSQFLITVTAVDSDKG---SNSTKIQIKILDVNEPPRDIYISNLLVKENLEPGTELAKLSTVDPDNNQEFVYSIPDTEYFELQGDELLSGTRMMDYEENSSLELVINSTDSGIPPHTIQRTFVIDVEDVNEPLIDIVLEAIAPVPEDLSLGSVLSKILVDDPE----------------ETQQHVCQVLPSL----VPFSVITSGNGTKELILSGVLDYETNSEFVLRIKCSDGEFDLTKEISIKIKNINEEPYGMTLSGSHTVLANGTT-GYSIGEVTVLDPDVEQTHIISIKGPNSDFIKAIYL-PIPVKNRKLVLTGPIPLDVLKKTPPVIDLTLTATDNGEPPLS--FNHTFSLPITNVQIFAAELPTISLDNQEVWEDSDIGQVVGRL-YSINQTIDEDIKFKLLFNPGDLFSI-KDNTYLVLVRNLTEVEGTSVIITVAVRNTET-FEMETQNITIFIKRVNNCEINGKKCDENARCVKSVNSTRHDCVCEFGFSGDGYSCDSIDLCQENHMPCRNNGT-CINEVNKYVCMCPEEFVGEHCQIQALS-SAEDPCSTIACQNGGVCLVNGDSRVVCSCQPGWQGELCELSEDDCIGIICHGNGTCVDKFMDYTCDCSGDRTGTHCEYQPSLCQADNVCVNEEVCIPLAD 3453 HSP 5 Score: 166.392 bits (420), Expect = 5.949e-37 Identity = 268/1147 (23.37%), Postives = 484/1147 (42.20%), Query Frame = 1 Query: 112 ISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLD--HENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEF-----------YTNSTDVXXXXXXXXXXXX-XYTKCLTEIRIQFELGFNFERQS-ELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDS---NLNSTIEK--CSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ-IPENE---PIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP-------EIIIKDQYGNKTEVFHI----MENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQT---LDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNC-LNCNEKFEFSNG------GSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFID-EKFIDIEIQCFNNGHTKIKSTTYSTALAI--EDINNEPATFSFNWTVDFVTENSNNISLGQLL--LMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFN--HSIVKIVNNEL-LTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINV 3381 IS L++E + ++E++ D P S I + I DANDPPT+++LS ++ EN +G++VG +S D D + S+ S V+ + +D+E A D H SV ++V D+N+ P + T E+ G IG + DPD D L F +NS+ Q N TKC E+R+ L NFE +S E+ ++ + D+N SL E + N ++ P D+ ++ + I EN ++ +G L DED + +++ + I H + I+ N+L + ++ L+YE + + D L F+K++ +++ +NE P ++L P V+ N G ++G +++D + +S ++ CS+ +F I LK + + ++T + I D G + I L I + P+ + L N + +PEN +G + N N+ +N +Y L F +E + L + FD E + ++ + G N+ F IEI N NE P I+K+ T + I E N++ T+ T+ P D N I D + + LT+ Q LD+E+ F + + D + + I I +++VN+ P + + S+ + EN + N +D D+ D+ S+ + KFE + G+ + +++ D+E + + + A+DS S ++ I I D N+PP ++ ++ +E + K++ D DN NQ I ++F + Q E++ + TR +D E+ +E+ N+ + I T I ED+ NEP + ++ + ++SLG +L ++ D ++ Q + LV ++ N +L+ LDYET + F++ D + + + ++I ++NE P + + + T+ I DPD Q H I+ N + + + + N +L LT LD V+ + + D+G+P LS F + I NV Sbjct: 2077 ISGALDYE-RVQQYTVEVMVVDNGDPSLSASTNIAIHITDANDPPTDLKLSAMEINENCEIGTVVGTLSAEDVDRGQNLTFSLSDTSNLVVEGE-QVKVTGNIDFEQIALLTFKATATDDGHPPRSVSKSFSVAVRDMNDPPTSLQFVTGTLVKDFMIPESMAMGGSIGTLEGVDPDGEDKLSFNMLEDGGGVFMLSNSSKCGPTTVQYQNAKSFIGTKCSIEVRLASVL--NFESESPEMTLKVQIKDKNGTSLIEKWTFNVKNTNDAPIDISID---GRQTEIPENEPSFIIGALQTTDEDEGDTFTYHV-ISHWELFRIR-GNKLEV--ASPLDYEEKSQYRVTIKSTDDGGLSFSKSFIFKVLSLNEKPNNISLNPKEVSNNAAVGDIVGLVTVVDPDNVDPDSPVQTHNCSVGGDGLG-VFTIDHGSNNLKVVSAIPVDRT-DMTIIITCKDDGSPPLEYSQNISLIIKEIVTIPKEVKLINQKPVPENTDSFTVGKF-QVFNMLTNEPVENEMYLYFLLDYGAPFTLEGDLLKTTKAFDFEMQQSVKVAVNAMAFGS---NLHGEFTIEIENVNEAPIGIGIYGGGILKENSAEGTIIGDINTRDQEKNQI-YTY-TLDAIYPGLSDPGNASIYKD-----------VFKLHNRTLTVGQPGKFLDFEKFPVFSVLVTSTDSGLPPLSYAGVIRIVLQDVNDQPGNIFLSNSQ-----VYENSLAGTEVGNLTVSDEDKKDLHSCSVATTGVPFKIKFEVGDNPYVELDGTNTVVTKTE-LDFE--VLSQFLITVTAVDSDKGSNSTKIQIKILDVNEPPRDIYISNLLVKENLEPGTELAKLSTVDPDN----NQEFVYSIPDTEYFEL----QGDELL-SGTRMMDYEENSSLEL-VINSTDSGIPPHTIQRTFVIDVEDV-NEPL---IDIVLEAIAPVPEDLSLGSVLSKILVDDPEETQQHVCQVLPSLVPFSVITSGNGTKELILSGVLDYETNSEFVLRIKCSDGEFDLTKEISIKIKNINEEPYGM-TLSGSHTVLANGTTGYSIGEVTVLDPDVEQTHIISIKG--PNSDFIKAIYLPIPVKNRKLVLTGPIPLD-VLKKTPPVIDLTLTATDNGEPPLSFNHTFSLPITNV 3167 HSP 6 Score: 150.984 bits (380), Expect = 2.353e-32 Identity = 323/1465 (22.05%), Postives = 597/1465 (40.75%), Query Frame = 1 Query: 124 LNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPP-----------TNIQLSNWKVEENILVGSLVGQISVVDEDLDDS--FKCSVKSDSPFN---------VDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRI-------------------------------------------QFELGF-----NFERQSELYFQISVTDRNNNSLSEIVKIIILNVDEN--PTDLKLNDSTSNKVLIEENSS-NYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKD--QILIFNKTYFIQLIDVNEAPQGLTLYPST------VTENIPSGSVIGKFSILDSN-----------------LNSTIEKCSLQLITFN--EIFLISQFQLELKDNTRLDYE-KTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ--IPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDK------INCQIISDN-SRFLVQKKSEIKNIF------QYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPP-TVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLK-------WFSILNISQNLEIVTTATRFID-EKFIDIEIQCFNNGHTKIKSTTYSTALAI--EDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVL-------VSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLI--DKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYF-------GISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWN-EKSEIGLLIANLSANDPEGSQVQFV----LNS--CKNVECPFYILQNSSIFLNK--SLQVLTENDQ-LEFEVTVSD----ILNTNVSLSLEVT---IFRENLAQISMEFKDVMNLPENSPIGSKV 4038 L+FE+++ +L I A+D P + ++D N+ P T ++ + EN + L+GQI V D D +D+ + + S N V +L D+ET + +D + SS + +++ D N+ P ++ E T +E S++ +I + +D D + YL+F T V + Y +RI Q +L F ++ER + ++ V D + SLS I I D N PTDLKL + + I EN +G LSA D D + +F + +D+ + + E +K + +++E + F A D +K++ + + D+N+ P L T + E++ G IG +D + + S KC + + + F+ ++ +E++ + L++E ++P L +++ D +++ + + + N+ P ++S+ Q IPENEP +I + D D+ T Y + + + F I NKL + D+E + Y++TI D+G L+ SK+F ++L+ NE P I N EV + N + +TV +PD D NC + D F + S + + D+TI T + + E + +N + I+K + + P ++ + + + N G + N +T +P +N++ Y +L + F+ G LK ++ FD+E + + +KV + A+ + G ++ E I I++ N+ P + ++ + IIG +N D++ Y +I L + + + V +F+D EKF + + + + +Y+ + I +D+N++P + + V ENS + L ++D K L + + V +N ++++ N+ + LD+E + FLI+ T + DK SN S ++++ILDVNE P +I + NL + E P +A DPD NQ + I + E F ++ +ELL+ +D ++ + I D G P +IQ F I + +VN+ P L + + E ++ +VL+ ++D + H C S G + ++ LDYET ++ + C D +++ I I+++NE P + +S G I ++ DP+ Q + NS K + P + +N + L L VL + ++ +T +D L+ N + SL +T IF L IS++ ++V E+S IG V Sbjct: 1805 LDFETQSM-YNLTITAQDDGTPPAQVSKTFQITVIDVNEAPFGLLITSSNMNTKFPVNQPIILENSVRNVLIGQIVVQDYDTEDAVTMRTTNMQISIVNQQCVPTVKMVHCTADLRAAVVFDHETTPSLSAELTAVDRQGSSATVQFNLTIQDTNDPP----IDINAGEDTYTVDEGSRN-IKITTLTASDVD-SAYLDFETKPQHVLKIRATDNGSPPLYVDKSFTVRIPEDSLPYTVVGILTGEDPDNVNKPTQTLKFSLADPDEKMFAVNQTQLMFISGALDYERVQQYTVEVMVVDNGDPSLSASTNIAIHITDANDPPTDLKL-----SAMEINENCEIGTVVGTLSAEDVDRGQNLTFSL----SDTSNLVVEGE-QVKVTGNIDFEQIALLTFKATATDDGHPPRSVSKSFSVAVRDMNDPPTSLQFVTGTLVKDFMIPESMAMGGSIGTLEGVDPDGEDKLSFNMLEDGGGVFMLSNSSKCGPTTVQYQNAKSFIGTKCSIEVRLASVLNFESESPEMTLKVQIKDKNGTSLIEKW--TFNVKNTNDAPIDISIDGRQTEIPENEP-SFIIGALQTTDEDEGDTFTYHVISHWELFRIRGNKLEVASPLDYEEKSQYRVTIKSTDDG--GLSFSKSFIFKVLSLNEKPNNISL----NPKEVSN---NAAVGDIVGLVTVVDPDNVDPDSPVQTHNCSVGGDGLGVFTIDHGSNNLKVVSAIPVDRTDMTIIITCKDDGSPPLEYS------QNISLIIKEIVTI------PKEVKLINQKPVPENTDSFTVGKFQVFNMLTNEPVENEMYLYFLL-----DYGAPFTLEGD--LLKTTKAFDFE--MQQSVKVAVNAM-AFGSNLHGEFTIEIENVNEAPIGIGIYGGGILKENSAEGTIIGDINTRDQEKNQIYTYTLDAIYPGLSDPGNASIYKDVFKLHNRTLTVGQPGKFLDFEKFPVFSV-LVTSTDSGLPPLSYAGVIRIVLQDVNDQPGNIFLSNSQ--VYENSLAGTEVGNLTVSDEDKKDLHSCSVATTGVPFKIKFEVGDNPYVELDGTNTVVTKTELDFEVLSQFLITVTAVDSDKGSN-STKIQIKILDVNEPPRDI--YISNLLVKENLEPGTELAKLSTVDPDNNQEFVYSIP----DTEYF-----ELQGDELLSGTRMMDYEENSSLELV---INSTDSGIPPHTIQRTFVIDVEDVNE-PLIDIVLEAIAPVPEDLSLGSVLSKILVDDPEETQQHVCQVLPSLVPFSVITSGNGTKELILSGVLDYETNSEFVLRIKCSDGE-FDLTKEISIKIKNINEEPYGMTLSGSHTVLANGTTGYSIGEVTVLDPDVEQTHIISIKGPNSDFIKAIYLPIPV-KNRKLVLTGPIPLDVLKKTPPVIDLTLTATDNGEPPLSFNHTFSLPITNVQIFAAELPTISLDNQEVW---EDSDIGQVV 3194 HSP 7 Score: 130.568 bits (327), Expect = 3.774e-26 Identity = 296/1368 (21.64%), Postives = 534/1368 (39.04%), Query Frame = 1 Query: 124 LNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDED------------LDDSFKCSVK-SDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSV--INKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEF-YTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNS--LSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTD------------SVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTE----NIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI-FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTF-ATITVFEPDFDDKINCQIISD-NSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIIN--------ITENIQGYQSIANFITTD--PDQNDVIKYSI--------LNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVE--KDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTAT-RFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSN-NISLGQLLL----MTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDP---LDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYA------TDPDYNQIHSF--DIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGP-----TAINYLTKLTA----IKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISN-------------SSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWN-EKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQ-------NSSIFLNKSLQVLTENDQLEFEV 3900 L+FE+ N ++ I+AKD P S + V + D N+ P NI+LS KV E G ++G +S D D LDD + V+ S D F D+E +++ V ++ D + + + + V D N+ P + + E ++ ENS GT IG + D D L F N TDV + ++E Q + +D + + V + +L+V+E P+ +K+ + + E+ ++G ++ D D+ E SF + +TD I+ L +K L+YE+ V L + I + DVNE P + L ++T + + + S D++LN + SLQ + + + F I +L +K + L++E Y L I VTD G + I ++I D NE PE LSL N+++ NS V T G ++E Y +T+ V DNG P + + +++ + N+ P N T H ++++ ++ T ++V + D D ++S + +FLV + ++ + +Q L E N ++I ++ D + V + P +++D + E + + EN+ I + + DQN V I L ++C+ + + + +K D+E + ++ D G L EV I++ N+ P + T + S E K ++ V D D T++ + P + FS L+ L + A F IDI +Q + G +K + + +ED+N +P S + + V E S +GQL + +L + ++L +++ I DN LDYET N+F + T D S N +++L +Q++DVN+ P + + P + + +PD ++S D +V G N ++K N+LD + + + I +DDG P + F I +I+VN+ P T+ N TK I E++ N ++ ++D DT+D +N I N + + A D+ET + + D+ G + + F + I+D N+PP ++ D + ++ + I L+A+D + + + F P ++L+ + ++++KS V D L + V Sbjct: 796 LDFEN-INTYTIRIVAKDSGKPAMSCEKFVTVRVQDENEAPRNIRLSANKVPELSEPGFVIGTLSTEDPDNSVREVQQFVYSLDDDIRGQVEVKKSMLQCDGQPCKF-----DFEKESQVSVKVKVTDSGSPPLTFVETLTLEVIDQNDPPQDLRL--VGESIV----ENSPPGTIIGKLTAFDEDVGQTLSFTLLNYTDVFVLKGDNSLATIT--------------SLDYEVQPVYAISVKCSDERGDPKFVDSTVTVKVLDVNEPPSFIKVTEIH----VPEDRKVGEAIGTVTVEDADLKEQLSFTVTRGYTDFMITNTSCFTESGQGIRCVGSLALKHP--LDYEAVSTLPLAVSVQDSGGLAATHSQMISVDDVNEPPTDILLNGKSLTSLSVYEMTQNDTLAELSAHDTDLNQS-HIFSLQ--SGDPVNFEIIGNKLRVKSSAVLNFETQNVYRLAINVTDNGLPPLSMVKAISVQIIDVNEPPETLSLDNSKV-----------------GPANSECVQTGG--------------PGCSLNYERSSMYNVTVLVSDNGVPPQSSVFSLTVQLTDVNDRPT--------NMTLSGHKIQSDAVKGTLIGQLSVMDEDADQSHTFSLVSGGDGQFLVSNEGKVSK------STDQPL--ESGNVYDIVVQAVDSGQPQLKVTSTFQVTVLGIKAP---VSVDFTSEEGVGSFPVNHPVVMENLASGSVIGYLVGVNNGMDQNLVFSLEIKEGENPFRLENVSCSSADDLTK--CTVGVKMQNILDFEKQTSVSVTAIVENKDGGKLVEMFEV--VIENENEAPKDIRPSSTDL-SVQENSKGQMVTMFLVSDPDAGDTHSFT--LLGNPGQKFS-LSTQGQLSVAKDAVIDFEKSPAIDIMVQVTDRGGLSLKK---NFTVRVEDVNEKPTQISLSQ--NKVKEMSEPGTVIGQLTTEDEDLDQTHTYTLMDNAGGRVLLNGTTLQVAIRGDNCDERGGSSCLLDYETMNSFDVVVTTQDSGSPSLNLTVSLTIQVVDVNDPPHHL------VLSVTALPEDTRVGELLGNIEVNNAEPDQEVMYSISEDQDVFVVEG---NKVVLK----------NALDFETQ---SMYNLTITAQDDGTPPAQVSKTFQITVIDVNEAPFGLLITSSNMNTKFPVNQPIILENSVRNVLIGQIVVQDYDTEDAVTMRTTNMQISIVNQQCVPTVKMVHCTADLRAAVVFDHETTPSLSAELTAVDRQGSSATVQFNLTIQDTNDPPIDINAGEDTYTVDEGSRNIKITTLTASDVDSAYLDFETK-------PQHVLKIRATDNGSPPLYVDKSFTVRIPEDSLPYTV 2036 HSP 8 Score: 117.472 bits (293), Expect = 3.463e-22 Identity = 215/927 (23.19%), Postives = 381/927 (41.10%), Query Frame = 1 Query: 1111 GAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLI-----TFNEIFLISQFQLEL-KDNTRLDYEKTPAY---NLGIR----VTDYGQENI----VTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKD-FYIENNKLLSGTVFDHENRPG--YQITITVFDNGDPKLNVSKTFDIEILNSNENP---EIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISD-NSRFLVQKK--SEIKNIFQY---DLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLE--VPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSIL--NISQNLEIVTTATR---------FIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNIS-LGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSI---NLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQK-----IIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAI----NYLTKLTAIKESANINTVLAXXXXXXXXXXXXH---QCHGSNSYFGISNSSIYIAKR--LDYETFTKMETIVVCFDQSGLNVSSVFQIDIE--DVNEPPENVKISNDQ 3705 GA+ D T+ ++++ N+AP+ L P+ + EN +G +G FS D + N + SL L+ F + SQ L++ KD+ L + Y N+ + VT GQ++ ++ F + + ++D N++PE++++ + IPE G + + D D++ Y L + F + N L+S FD E G +QI I DNG P V T + + NE P + + E ++ N TI V + D D + + D R ++ K S+++ I Y L + D+E I++ ++D + + + NVN+ P+ + ++ + + EN IA D D +D + +L+ + + E G +L E D+E NI + I A DSG ++ E V + +QD N+ P L+ +P E F+IG ++ D DN S+ + ++ L +I +E+ + + F E + ++++ ++G + T+ L +E I+ + + ENS + +G+L + ++L S +L ++ + + DNS LDYE + + IS D+ + + V++LDVNE PS IK E + + E I T D D + SF + + +I N F S I L + LD ++ + + +D G L+ I + +VN+ PT I LT L+ + + N LA D D + H G F I + + + L++ET + D +S V I ++ DVNEPPE + + N + Sbjct: 377 GAFVD------STFQFEILNENDAPKSAKLTPNAIPENSMAGVHVGCFSAQDDDPNQNV---SLLLVDSEHKMFASYYNGSQLCLKVSKDSNPLCTSEGGKYCVLNMEEQQVHFVTLMGQDDYSPPGISYFNLAVTLTDVNDKPESVTMEPDSIPEEVEPGTPLTALKTIDEDRDQEFQYRLIEDSSGLFSVVNGSLISSVKFDFEEDAGKEFQIKIQSDDNGSPSYRVVSTIVFTVGDVNEAPYDLHLTSSNAPIQFPEDKPKVKENAKAAIVGTIVVKDQDKGDNLEINLADDLGGRLVIMNKMCSQVQGINTYCLGTLVTFGSFDHETEGEVNISVSVSDNGSLQTTAVWTMEILNVNDAPSDILLNEASVKEGTVVEN-HNNALIAVLSAADDDVDDTHSFHLLDSADGKFRIE----GRQLMTSELANLDFE-NINT-YTIRIVAKDSGKPAMSCEKFVTVRVQDENEAPRNIRLSANKVPELSEPGFVIGTLSTEDPDN---------SVREVQQFVYSLDDDIRGQVEVKKSMLQCDGQPCKFDFEKESQVSVKVKVTDSGSPPL---TFVETLTLEVIDQNDPPQDLRLVGESIVENSPPGTIIGKLTAFDEDVGQTL-----SFTLLNYTDVFV-LKGDNSLATITSLDYEVQPVYAISVKCSDERGDPKFVDSTVTVKVLDVNEPPSFIKVTE--IHVPEDRKVGEAIGTVTVEDADLKEQLSFTVTRGYTDFMITNTSCFTESGQGIRCVGSLALKHPLDY---EAVSTLPLAVSVQDSG--GLAATHSQMISVDDVNEPPTDILLNGKSLTSLSVYEMTQ--NDTLAELSAHDTDLNQSHIFSLQSGDPVNFEIIGNKLRVKSSAVLNFETQNVYRLAINVTDNGLPPLSMVKAISVQIIDVNEPPETLSLDNSK 1260 HSP 9 Score: 98.2117 bits (243), Expect = 2.564e-16 Identity = 143/544 (26.29%), Postives = 238/544 (43.75%), Query Frame = 1 Query: 124 LNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKS------------DSPF-NVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRN--NNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGE-LSAI---DEDINELYSFQILI-LHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPS-TVTENIPSGSVIGKFSILDSNLNST----IEKCSLQLITFNEIFL---ISQFQLELKDNTRLDYEK--TPAYNLGIRVTDYGQENIVTDFEIILEISD----ANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKD-FYIENNKLL 1650 L+FE K S+ + + D +P S +I + + D ND P NI LSN +V EN L G+ VG ++V DED D CSV + D+P+ +D + TK LD+E ++F + + +D + S K +I + D+NE P IY++ L EN + GT + + DPD N + T+ + L+ R+ ++E S L I+ TD +++ I + +V+E D+ L I + SLG LS I D + + + Q+L L SV + S L+YE++ + + D K I++ ++NE P G+TL S TV N +G IG+ ++LD ++ T I+ + I I+L + +L L LD K P +L + TD G+ + + L I++ A E P +SL N ++ E+ IG ++ + + + + + + L N D F I++N L Sbjct: 2717 LDFE-KFPVFSVLVTSTDSGLPPLSYAGVIRIVLQDVNDQPGNIFLSNSQVYENSLAGTEVGNLTVSDEDKKDLHSCSVATTGVPFKIKFEVGDNPYVELDGTNTVVTKTELDFEVLSQFLITVTAVDSDKGSNSTKIQIKILDVNEPPRDIYISN------LLVKENLEPGTELAKLSTVDPDNNQEFVYSIPDTEYFELQGD---------ELLSGTRM-----MDYEENSSLELVINSTDSGIPPHTIQRTFVIDVEDVNEPLIDIVLE-------AIAPVPEDLSLGSVLSKILVDDPEETQQHVCQVLPSLVPFSVITSGNGTKELILSGVLDYETNS-EFVLRIKCSDGEFDLTKEISIKIKNINEEPYGMTLSGSHTVLANGTTGYSIGEVTVLDPDVEQTHIISIKGPNSDFI--KAIYLPIPVKNRKLVLTGPIPLDVLKKTPPVIDLTLTATDNGEPPLSFNHTFSLPITNVQIFAAELP-TISLDNQEVWEDSDIGQVVGRLYSINQTIDEDIKFKLLFNPGDLFSIKDNTYL 3228 HSP 10 Score: 77.411 bits (189), Expect = 5.047e-10 Identity = 133/576 (23.09%), Postives = 243/576 (42.19%), Query Frame = 1 Query: 3304 VEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANI----NTVLAXXXXXXXXXXXXHQCH---GSNSYFGISNSSIYIAK--RLDYETFTKMETIVVCFD--QSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQN---SSIFLNKS-LQVLTENDQLEFEVTVSDILNTNVSLSLEVT-------IFRENLAQISMEFKDVMNLP-----------ENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIV-DFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLST-TINVTDVDEPLKEIIVNITD-SIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAXXXXXXXXXX-XXEDKNDPAIDLVWNGSTIIDLDL--TTDGSFLGNLLVIDEDLNQMHDIMIQYPANKYFYIIN---------CCDLMTQNLEYAWTGPLNASFIITDNGIPPMKSIFNISFNFIE 4887 + + D+G SL + + ++I+NVND P+ I L ++KE + N ++A+ D+D DD H H ++ F I + ++ LD+E +V D + ++ + ++D NE P N+++S ++ E SE G +I LS DP+ NS + V+ Y L + + + KS LQ + + +FE + VS+ ++VT F E L ++E D + P ENSP G+ + ++ F + ++ + + + F++ D + SLDYE ++VKC + ST T+ V DV+EP + +T+ + E + IG + ++D ++ V + + + +C T +L + +YE + + ++ D+ + + ++D N+P D++ NG ++ L + T L L D DLNQ H +Q F II + TQN+ + +TDNG+PP+ + IS I+ Sbjct: 704 ISVSVSDNG--SLQTTAVWTMEILNVNDAPSDI--LLNEASVKEGTVVENHNNALIAVLSAADDDVDDTHSFHLLDSADGKFRIEGRQLMTSELANLDFENINTYTIRIVAKDSGKPAMSCEKFVTVRVQDENEAPRNIRLSANKVPELSEPGFVIGTLSTEDPD--------NSVREVQQFVYSLDDDIRGQVEVKKSMLQCDGQPCKFDFE------KESQVSVKVKVTDSGSPPLTFVETL---TLEVIDQNDPPQDLRLVGESIVENSPPGTIIGKLTA-FDEDVGQTLSFTLLNYTDVFVLKGDNSLATITSLDYEVQPVYAISVKCSDERGDPKFVDSTVTVKVLDVNEPPS--FIKVTEIHVPEDRKVGEAIGTVTVEDADLKEQLSFTVTRGYTDFMITNTSCFT-ESGQGIRCVGSLALKHPLDYE-AVSTLPLAVSVQDSGGLAATHSQMISVDDVNEPPTDILLNGKSLTSLSVYEMTQNDTLAELSAHDTDLNQSHIFSLQSGDPVNFEIIGNKLRVKSSAVLNFETQNV-------YRLAINVTDNGLPPLSMVKAISVQIID 1246 HSP 11 Score: 65.4698 bits (158), Expect = 2.195e-6 Identity = 94/391 (24.04%), Postives = 169/391 (43.22%), Query Frame = 1 Query: 3565 LDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSS--IFLNK-SLQVLTENDQLE----------------FEVTV------SDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPN--INCEIFSDGNFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVNITDS------------IQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEI---LLHEIRFSIECGDAXXXXXXXXXXXXEDKNDPAIDL 4611 +D+E ++ +V D+ GL++ F + +EDVNE P + +S ++ E SE G +I L+ D + Q + ++ N+ + LN +LQV D + F+V V S LN VSL+++V + + + V LPE++ +G + I++N N P+ + I D + F++ KV+L +LD+ET S +T+ Q+ ++S T +T +D + IT S I E N IG I+++D + A+ N+ + N + CV M +C + +L + F++E L E+ G + + ++ ++D NDP ID+ Sbjct: 1599 IDFEKSPAIDIMVQVTDRGGLSLKKNFTVRVEDVNEKPTQISLSQNKVKEMSEPGTVIGQLTTEDEDLDQTHT-----------YTLMDNAGGRVLLNGTTLQVAIRGDNCDERGGSSCLLDYETMNSFDVVVTTQDSGSPSLNLTVSLTIQVVDVNDPPHHLVLS---VTALPEDTRVGELLGNIEVN---NAEPDQEVMYSISEDQDVFVVEGNKVVLKNALDFETQSMYNLTITA-QDDGTPPAQVSKTFQITVIDVNEAPFGLLITSSNMNTKFPVNQPIILENSVRNVLIGQIVVQDYDTE-DAVTMRTTNMQISIVN-QQCVPTVKMVHC--TADLRAAVVFDHETTPSLSAELTAVDRQGSS---ATVQFNLTIQDTNDPPIDI 1964
BLAST of Protocadherin Fat 4 vs. TrEMBL
Match: A0A2A5EKC8 (Uncharacterized protein (Fragment) OS=Rhodobiaceae bacterium OX=2026785 GN=COA62_14115 PE=4 SV=1) HSP 1 Score: 244.973 bits (624), Expect = 3.278e-61 Identity = 283/1195 (23.68%), Postives = 500/1195 (41.84%), Query Frame = 1 Query: 217 VAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNV-DANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENN--KLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP-EIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKF---IDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLM-TDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQ-SINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKI---IVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAK--RLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSAND 3759 +A+ D N+ PT+I LSN V EN G++VG +S D D DS +V D+ F V L LD+E +V + D ++ I+V D+NE P I ++ T + EN+ +G +G + D D D + + + + E++++ + + E + ++ TD + SE I + +V+E PTD+ L++S+ + EN++ +G LS D D + +S+ + + V EL +K L++E++ VV +++T+ I + DVNE P + L ++V EN +G+V+G S D + S + F + +L+LK LD+E + ++ + TD G F I ++ D NE P +++LSN + EN G ++ ++ D D T Y +D + F + KL +G DHE + +T D+G S+TF I + + NE P +I + + + N T++ + D D + + D++RF V E+K L +LD+E + ++ + D T I V +VNE PT +A+ + ++ EN G + TTD D D Y++ + +FE G +L LK D+E+ + V++ DSGG + + + D N+ PT L+ + ++G ++ D D T+ S F ++ L+ A +D + +D+ + ++G S T+S +A+ D N P + + V EN+ +G L D + + +V +K++ LD+E ++ + T D S + + D NE P++I N ++ E + + + T TD D HS+ + +V GE+ + V + ++E +S+DVVV+ D G + S F I + +VN+GPT I L+ + + +A V+ D D D H ++ F + + + LD+E ++ IV D G S F + + DVNE P ++ +SN E + G ++ LS D Sbjct: 287 LAVGDVNEGPTDIALSNASVAEN-AAGAVVGTLSTTDVDAGDSHTYAVD-DARFEVVGGELKLKAGVSLDHEAADSVDVTVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNT------SVAENA-AGAVVGTLSTTDVDAGDSHTYAVD--------------DARFEVVGGELKLKAGVSLDHEAADSVDVTVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNSS-----VAENAAGAVVGTLSTTDVDAGDTHSYAVDDARFEVV----GGELKLKAGVSLDHEAADSVDVVVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNASVAEN-AAGAVVGTLSTTDVDAGD-----SHTYAVDDARFEVVGGELKLKAGVSLDHEAADSVDVTVTTTDSGGATYSETFSIAVD--DVNEGPSDIALSNASVVEN-AAGAVVGTLSTTDVDAGDTHSYAVD--DARFEVVGGELKLKAGVSLDHEAADNVDVIVTTTDSG--GATYSETFSIAVGDVNEGPTDIALSNAS---------VAENAAGAVVGTLSTTDVDAGDTHSYAV--DDARFEVV-GGELK------LKAGVSLDHEAADSVDVVVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNA-----SVAENAAGAV-VGTLSTTDVDAGDTHSYAVDDA-----RFEVVGG--ELKLKAGVSLDHEAX--DSVDVIVTTTDSGGATYSETFSLXVGDVNEGPTDIALSNXSVAENAAG-AVVGTLSTTDVDAGDTH-----SYAVDDARFEVVGGELKLK----AGVSLDHEAADSVDVVVTTTDSGGAXY-SETFS--IAVGDXNEGPTDIALSNA--SVAENAAGAIVGTLSTTDVDAGDTHSYAVDDARFEVVGGELKLKAGV--------SLDHEAADSVDVIVTTTDSGGATYSETFSIAVGDANEGPTDIA--LSNASVAENAAGAV-VGTLSTTDVDAGDTHSYAVDDARFEVVGGELKLKAGVSL-DHEA---ADSVDVVVT-----------TTDSGGATYS--ETFSIAVGDVNEGPTDI-ALSNASVAENAAGA--VVGTLSTTDADAGDTHSYAVDDARFEVVGGELKLKAGVSLDHEAADSVDVIVTTTDSGGATYSETFSLTVGDVNEGPTDIALSNSSVAENA-AGAVVGTLSTTD 1356 HSP 2 Score: 233.802 bits (595), Expect = 8.586e-58 Identity = 275/1184 (23.23%), Postives = 493/1184 (41.64%), Query Frame = 1 Query: 217 VAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNV-DANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENN--KLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP-EIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKF---IDIEIQCFNNGHTKIKSTTYST--ALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLM-TDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQ-SINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKI---IVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAK--RLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKS 3720 +A+ D N+ PT+I LSN V EN G++VG +S D D D+ +V D+ F V L LD+E +V++ D ++ I+V D+NE P I ++ + EN+ +G +G + D D D + + + + E++++ + + E + ++ TD + SE I + +V+E P+D+ L SN ++E N++ +G LS D D + +S+ + + V EL +K L++E++ +V +++T+ I + DVNE P + L ++V EN +G+V+G S D + T + F + +L+LK LD+E + ++ + TD G F I + D NE P +++LSN + EN G ++ ++ D D T Y +D + F + KL +G DHE + +T D+G S+TF + + + NE P +I + + + N T++ + D D + + D++RF V E+K L +LD+E + ++ + D I V + NE PT +A+ + ++ EN G + TTD D D Y++ + +FE G +L LK D+E+ + V++ DSGG + I++ DAN+ PT L+ + ++G ++ D D T+ S F ++ L+ A +D + +D+ + ++G TYS ++A+ D+N P + + V EN+ +G L D + + +V +K++ LD+E ++ + T D S + + DVNE P++I N ++ E + + + T TD D HS+ + +V GE+ + V + ++E +S+DVVV+ D G + S F I + +VN+GPT I L+ + + +A ++ D D D H ++ F + + + LD+E ++ IV D G S F I + D NE P ++ +SN E + Sbjct: 475 IAVGDVNEGPTDIALSNSSVAEN-AAGAVVGTLSTTDVDAGDTHSYAVD-DARFEVVGGELKLKAGVSLDHEAADSVDVVVTTTDSGGATYSETFSIAVGDVNEGPTDIALSN------ASVAENA-AGAVVGTLSTTDVDAGDSHTYAVD--------------DARFEVVGGELKLKAGVSLDHEAADSVDVTVTTTDSGGATYSETFSIAVDDVNEGPSDIAL----SNASVVE-NAAGAVVGTLSTTDVDAGDTHSYAVDDARFEVV----GGELKLKAGVSLDHEAADNVDVIVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNASVAEN-AAGAVVGTLSTTDVDAGDT-----HSYAVDDARFEVVGGELKLKAGVSLDHEAADSVDVVVTTTDSGGATYSETFSIA--VGDVNEGPTDIALSNASVAEN-AAGAVVGTLSTTDVDAGDTHSYAVD--DARFEVVGGELKLKAGVSLDHEAXDSVDVIVTTTDSG--GATYSETFSLXVGDVNEGPTDIALSNXS---------VAENAAGAVVGTLSTTDVDAGDTHSYAV--DDARFEVVGG-ELK------LKAGVSLDHEAADSVDVVVTTTDSGGAXYSETFSIAVGDXNEGPTDIALSNA-----SVAENAAGAI-VGTLSTTDVDAGDTHSYAVDDA-----RFEVVGG--ELKLKAGVSLDHEAA--DSVDVIVTTTDSGGATYSETFSIAVGDANEGPTDIALSNASVAENAAG-AVVGTLSTTDVDAGDTH-----SYAVDDARFEVVGGELKLK----AGVSLDHEAADSVDVVVTTTDSG-----GATYSETFSIAVGDVNEGPTDIALSNA--SVAENAAGAVVGTLSTTDADAGDTHSYAVDDARFEVVGGELKLKAGV--------SLDHEAADSVDVIVTTTDSGGATYSETFSLTVGDVNEGPTDIA--LSNSSVAENAAGAV-VGTLSTTDVDAGDTHSYAVDDARFEVVGGELKLKAGVSL-DHEA---ADSVDVVVT-----------TTDSGGATYS--ETFSIAVGDVNEGPTDI-ALSNASVAENAAGA--IVGTLSTTDVDAGDTHSYAVDDARFEVVGGELKLKAGVSLDHEAADSVDVIVTTTDSGGATYSETFSIAVGDANEGPTDIALSNASVAENA 1532 HSP 3 Score: 222.246 bits (565), Expect = 2.560e-54 Identity = 277/1196 (23.16%), Postives = 494/1196 (41.30%), Query Frame = 1 Query: 235 NDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNV---DANFNLFTKAPL--DYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENN--KLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKF---IDIEIQCFNNGHTKIKSTTYST--ALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLM-TDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQ-SINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKI---IVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAK--RLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPE 3765 N P +I LSN EN G++VG +S D D + F V D+ F V + N L K + D+E + +++I D S ++V D+NE P I ++ + EN+ +G +G + D D D + + + + E++++ + + E + ++ TD + SE I + +V+E PTD+ L++++ + EN++ +G LS D D + +++ + + V EL +K L++E++ V +++T+ I + DVNE P + L S+V EN +G+V+G S D + T + F + +L+LK LD+E + ++ + TD G F I + D NE P +++LSN + EN G ++ ++ D D + Y +D + F + KL +G DHE +T+T D+G S+TF I + + NE P I ++E N T++ + D D + + D++RF V E+K L +LD+E + ++ + D T I V +VNE PT +A+ + ++ EN G + TTD D D Y++ + +FE G +L LK D+E+ + V++ DSGG + I++ D N+ PT L+ + ++G ++ D D T+ S F ++ L+ A +D + +D+ + ++G TYS +L + D+N P + + V EN+ +G L D + + +V +K++ LD+E ++ + T D S + + D NE P++I N ++ E + I + T TD D HS+ + +V GE+ + V + ++E +S+DV+V+ D G + S F I + + N+GPT I L+ + + +A V+ D D D H ++ F + + + LD+E ++ +V D G S F I + DVNE P ++ +SN E + G ++ LS D + Sbjct: 195 NRAPDSISLSNTSFGEN-AAGAVVGTLSATDPDGNGPFTYEVN-DARFEVVELNGNVQLKLKPGVSFDHEATPQVDLVITVTDEGGLSHEQGFTLAVGDVNEGPTDIALSN------ASVAENA-AGAVVGTLSTTDVDAGDSHTYAVD--------------DARFEVVGGELKLKAGVSLDHEAADSVDVTVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNTS-----VAENAAGAVVGTLSTTDVDAGDSHTYAVDDARFEVV----GGELKLKAGVSLDHEAADSVDVTVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNSSVAEN-AAGAVVGTLSTTDVDAGDT-----HSYAVDDARFEVVGGELKLKAGVSLDHEAADSVDVVVTTTDSGGATYSETFSIA--VGDVNEGPTDIALSNASVAEN-AAGAVVGTLSTTDVDAGDSHTYAVD--DARFEVVGGELKLKAGVSLDHEAADSVDVTVTTTDSG--GATYSETFSIAVDDVNEGPSDIALSNA-------SVVE-NAAGAVVGTLSTTDVDAGDTHSYAV--DDARFEVV-GGELK------LKAGVSLDHEAADNVDVIVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNA-----SVAENAAGAV-VGTLSTTDVDAGDTHSYAVDDA-----RFEVVGG--ELKLKAGVSLDHEAA--DSVDVVVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNASVAENAAG-AVVGTLSTTDVDAGDTH-----SYAVDDARFEVVGGELKLK----AGVSLDHEAXDSVDVIVTTTDSG-----GATYSETFSLXVGDVNEGPTDIALSNX--SVAENAAGAVVGTLSTTDVDAGDTHSYAVDDARFEVVGGELKLKAGV--------SLDHEAADSVDVVVTTTDSGGAXYSETFSIAVGDXNEGPTDIA--LSNASVAENAAGAI-VGTLSTTDVDAGDTHSYAVDDARFEVVGGELKLKAGVSL-DHEA---ADSVDVIVT-----------TTDSGGATYS--ETFSIAVGDANEGPTDI-ALSNASVAENAAGA--VVGTLSTTDVDAGDTHSYAVDDARFEVVGGELKLKAGVSLDHEAADSVDVVVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNASVAENA-AGAVVGTLSTTDAD 1264 HSP 4 Score: 201.06 bits (510), Expect = 1.012e-47 Identity = 251/1102 (22.78%), Postives = 460/1102 (41.74%), Query Frame = 1 Query: 505 SVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQS--ELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENN--KLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP-EIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKF---IDIEIQCFNNGHTKIKSTTYST--ALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLM-TDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQ-SINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKI---IVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAK--RLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSAND 3759 SV + N APD I ++ T + EN+ +G +G + DPD N + N + + ++++ + G +F+ ++ ++ I+VTD S + + + +V+E PTD+ L++++ + EN++ +G LS D D + +++ + + V EL +K L++E++ V +++T+ I + DVNE P + L ++V EN +G+V+G S D + S + F + +L+LK LD+E + ++ + TD G F I + D NE P +++LSN+ + EN G ++ ++ D D T Y +D + F + KL +G DHE + +T D+G S+TF I + + NE P +I + + + N T++ + D D + D++RF V E+K L +LD+E + ++ + D T I V++VNE P+ +A+ + ++ EN G + TTD D D Y++ + +FE G +L LK D+E+ ++ V++ DSGG + I++ D N+ PT L+ + ++G ++ D D T+ S F ++ L+ A +D + +D+ + ++G TYS ++A+ D+N P + + V EN+ +G L D + + +V +K++ LD+E ++ + T D S + + DVNE P++I N ++ E + + + T TD D HS+ + +V GE+ + V + ++E +S+DVVV+ D G S F I + + N+GPT I L+ + + +A ++ D D D H ++ F + + + LD+E ++ IV D G S F I + D NE P ++ +SN E + G ++ LS D Sbjct: 190 SVEEPNRAPDSISLSNT------SFGENA-AGAVVGTLSATDPDGNGPFTYEVN------------DARFEVVELNGNVQLKLKPGVSFDHEATPQVDLVITVTDEGGLSHEQGFTLAVGDVNEGPTDIALSNAS-----VAENAAGAVVGTLSTTDVDAGDSHTYAVDDARFEVV----GGELKLKAGVSLDHEAADSVDVTVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNTSVAEN-AAGAVVGTLSTTDVDAGD-----SHTYAVDDARFEVVGGELKLKAGVSLDHEAADSVDVTVTTTDSGGATYSETFSIA--VGDVNEGPTDIALSNSSVAEN-AAGAVVGTLSTTDVDAGDTHSYAVD--DARFEVVGGELKLKAGVSLDHEAADSVDVVVTTTDSG--GATYSETFSIAVGDVNEGPTDIALSNAS---------VAENAAGAVVGTLSTTDVDAGDSHTYAV--DDARFEVV-GGELK------LKAGVSLDHEAADSVDVTVTTTDSGGATYSETFSIAVDDVNEGPSDIALSNA-----SVVENAAGAV-VGTLSTTDVDAGDTHSYAVDDA-----RFEVVGG--ELKLKAGVSLDHEAA--DNVDVIVTTTDSGGATYSETFSIAVGDVNEGPTDIALSNASVAENAAG-AVVGTLSTTDVDAGDTH-----SYAVDDARFEVVGGELKLK----AGVSLDHEAADSVDVVVTTTDSG-----GATYSETFSIAVGDVNEGPTDIALSNA--SVAENAAGAVVGTLSTTDVDAGDTHSYAVDDARFEVVGGELKLKAGV--------SLDHEAXDSVDVIVTTTDSGGATYSETFSLXVGDVNEGPTDIA--LSNXSVAENAAGAV-VGTLSTTDVDAGDTHSYAVDDARFEVVGGELKLKAGVSL-DHEA---ADSVDVVVT-----------TTDSGGAXYS--ETFSIAVGDXNEGPTDI-ALSNASVAENAAGA--IVGTLSTTDVDAGDTHSYAVDDARFEVVGGELKLKAGVSLDHEAADSVDVIVTTTDSGGATYSETFSIAVGDANEGPTDIALSNASVAENA-AGAVVGTLSTTD 1168
BLAST of Protocadherin Fat 4 vs. TrEMBL
Match: A0A2Z4UNV7 (Leukotoxin OS=Rhodobiaceae bacterium OX=2026785 GN=ltxA PE=4 SV=1) HSP 1 Score: 245.743 bits (626), Expect = 3.656e-61 Identity = 324/1408 (23.01%), Postives = 592/1408 (42.05%), Query Frame = 1 Query: 124 LNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNV-DANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI-FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQ--TLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYN-QIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYST--ALAIEDINNEPATFSF-NWTVDFVTENSNNISLGQLLLM-TDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLID-KNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNEL-LTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYI--AKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSAND-PEGSQVQFVLNSCKNVECPFYILQNSSIFLNK-SLQVLTENDQLEFEVTVSDILNTNVS--LSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFS--DGNFFII-VDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVN 4287 L+ E++++ +++E+ D S+ F I V D N+ P++I LSN V+EN G++VG +S D D DS +V D+ F V + L LD+ET++ V + D ++ I+V D+NE P I ++ + +EN+ +G +G + D D D + + + + +++++ + + E +S + +++ TD + + SE I + +V+E P+D+ L++++ ++EN++ +G LS D D + +++ + + V +L +K+ L++E+ V +++T+ I + DVNE P + L ++V EN +G+V+G S D ++ ++ F + L+LKD LD+E + + + TD F I + D NE P ++SLSN + EN G + ++ D D T Y +D + + KL +G DHE + +T D S+TF I + + NE P I N + ++ N T++ + D D + D++RF + DL + +LD+E + + + D T I V +VNE P+ +A+ + ++ EN G + + TTD D D Y++ + +FE G L LK+ DY N + V + DS G + IS+ D ND PT L+ + ++G ++ D D ++ ++ + + + L +L+ T E + +E+ T TYS +A+ D+N +P+ S N +VD EN+ +G L D + + +V ++K++ LD+ETE++ + T D + S + + DVNE PS+I N ++ E + + + + ATD D H++ + + + ++V +L L D SLD + + VE+ D + F I + +VN+GP+ I L+ + + SA V+ D D D H ++ F + + + LD+ET + + V D SG S F I + DVNE P ++ +SN +E + G ++ +LS D +G + ++ + F ++ + SL TE+ + EVT +D S ++ V E + IS+ V + +GS + + + + +S D F ++ D K+ SLD+ET S + V V + + TI V DV+E +I ++ Sbjct: 627 LDHETESS-VAVEVTTTDASGATYSETFTITVG--DVNEGPSDISLSNASVDEN-AAGAVVGTLSTTDVDAGDSHTYAVD-DARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSN------ASVDENA-AGAVVGTLSTTDVDDGDTHSYAVD--------------DARFEVVGGDLKLKDGVSLDHEAESSVAVEVTTTDASGATYSETFNIAVGDVNEGPSDISLSNAS-----VDENAAGAVVGSLSTTDVDDGDTHTYAVDDARFEVV----GGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNASVDEN-AAGAVVGSLSTTD------VDDGDTHTYAVDDARFEVVGGDLKLKDGVSLDHEAESSVAVEVTTTDASGATYSETFTIA--VGDVNEGPSDISLSNASVDEN-AAGAVAGSLSTSDVDDGDTHSYAVDDARFEVVGGDLKLKNGVSLDHETESSVAVEVTTTDA--SGATYSETFTIAVGDVNEGPSDI---SLSNAS-----VDENAAGAVVGTLSTTDVDAGDSHTYAV--DDARF---------EVVGGDLKLKDGVSLDHESESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNT-----SVDENAAGAV-VGSLSTTDVDAGDSHTYAVDDA-----RFEVVGG--DLKLKDGVSLDY--NTDPSVDVTVTTTDSAGATYQETFSISVGDTNDAPTDISLDNLSVDENAAG-AVVGTLSTTDVDAGDSHTYAVDDARFEVVGGDLKLKDGVSLDHET-------ESSVAVEVTT-----TDASGATYSETFTIAVGDVNEDPSDISLSNASVD---ENAAGAVVGSLSTTDVDAGDSHTYAVDDARFEVVGGDLKLKDGV--------SLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIS--LSNASVDENAAGAV-VGSLSATDVDAGDSHTYAV----------DDARFEVVGGDLKLKDGVSLDHESESSVA---VEVTTTD--ASGATYSETFTIAVGDVNEGPSDI-ALSNSSVDENSAGA--VVGSVSTTDVDAGDTHTYAVDDARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDISLSNASVDENA-AGAVVGSLSTTDVDDGDTHSYSVDDAR-----FEVVGGDLKLKDGVSLDHETES-SVAVEVTTTDASGATYSETFTIAVGDVNEGPSDISLSNASVDENAAGAVVGS--------LSTTDVDDGDTHSYSVDDARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSE-TFTIAVGDVNEGPSDIALS 1892 HSP 2 Score: 227.639 bits (579), Expect = 1.401e-55 Identity = 314/1410 (22.27%), Postives = 586/1410 (41.56%), Query Frame = 1 Query: 124 LNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNV-DANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQ--TLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQ---CFNNGHTKIKSTTYST--ALAIEDINNEPATFSF-NWTVDFVTENSNNISLGQLLLM-TDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLID-KNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNEL-LTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYI--AKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSAND-PEGSQVQFVLNSCKNVECPFYILQNSSIFLNK-SLQVLTENDQLEFEVTVSDILNTNVS--LSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFS--DGNFFII-VDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVNI 4290 L+ E++++ +++E+ D S+ F I A+ D N+ P++I LSN V+EN G++VG +S D D DS +V D+ F V + L LD+E+++ V + D ++ I+V D+NE P I ++ T + +EN+ +G +G + D D D + + + + +++++ + ++ + ++ TD + E I + + ++ PTD+ L + + ++EN++ +G LS D D + +++ + + V +L +K+ L++E+ V +++T+ I + DVNE P ++L ++V EN +G+V+G S D + S + F + L+LKD LD+E + + + TD F I + D NE P ++SLSN + EN G ++ ++A D D + Y +D + + KL G DHE+ + +T D S+TF I + + NE P I N + ++ N +++ + D D + D++RF + DL + +LD+E + + + D T I V +VNE P+ +++ + ++ EN G + + TTD D D YS+ + +FE G L LK+ D+E+ + V + D+ G + I++ D N+ P+ L+ + ++G ++ D D+ T++ +S+ + E+V + D +D E + T TYS +A+ D+N P+ + N +VD EN+ +G L D + + +V ++K++ LD+ETE++ + T D + S + + DVNE PS+I N ++ E + + + + D D HS+ + + + ++V +L L D SLD + I VE+ D + F I + +VN+GP+ I+ ++ E+A V+ D D D H ++ F ++ + + LD+ET + + V D SG S F I + DVNE P ++ +SN +E + G ++ +LS D +G + ++ + F ++ + SL TE+ + EVT +D S ++ V E + IS+ V + +GS + + + + +S D F ++ D K+ SLD+E+ S + V V + + TI V DV+E V++ Sbjct: 1097 LDHETESS-VAVEVTTTDASGATYSETFTI--AVGDVNEGPSDISLSNASVDEN-AAGAVVGTLSTTDVDAGDSHTYAVD-DARFEVVGGDLKLKDGVSLDHESESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNT------SVDENA-AGAVVGSLSTTDVDAGDSHTYAVD--------------DARFEVVGGDLKLKDGVSLDYNTDPSVDVTVTTTDSAGATYQETFSISVGDTNDAPTDISL-----DNLSVDENAAGAVVGTLSTTDVDAGDSHTYAVDDARFEVV----GGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEDPSDISLSNASVDEN-AAGAVVGSLSTTDVDAGD-----SHTYAVDDARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIA--VGDVNEGPSDISLSNASVDEN-AAGAVVGSLSATDVDAGDSHTYAVDDARFEVVGGDLKLKDGVSLDHESESSVAVEVTTTDA--SGATYSETFTIAVGDVNEGPSDI---ALSNSS-----VDENSAGAVVGSVSTTDVDAGDTHTYAV--DDARF---------EVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDISLSNA-----SVDENAAGAV-VGSLSTTDVDDGDTHSYSVDDA-----RFEVVGG--DLKLKDGVSLDHETE--SSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDISLSNASVDENAAG-AVVGSLSTTDVDDGDTHS------------YSVDD--ARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNSSVD---ENAAGAVVGSLSTTDVDAGDSHTYAVDDARFEVVGGDLKLKDGV--------SLDHETESSVAVEVTTTDASGATYSETFNIAVGDVNEGPSDIA--LSNASVDENAAGAV-VGSLSTADVDDGDTHSYAV----------DDARFEVVGGDLKLKDGVSLDHEAESSIA---VEVTTTD--ASGATYSETFTITVGDVNEGPSDISLSNA--SVDENA-AGAVVGTLSTTDVDAGDSHTYAVDDARFEVAGGDLKLKNGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNASVDENA-AGAVVGSLSTADVDDGDTHSYAVDDAR-----FEVVGGDLKLKDGVSLDHETES-SVAVEVTTTDASGATYSETFTIAVGDVNEGPSDISLSNASVDENAAGAVVGS--------LSTTDVDDGDTHSYSVDDARFEVVGGDLKLKDGVSLDHESESSVAVEVTTTDASGATYSE-TFTIAVGDVNEGPSAGAVDL 2363 HSP 3 Score: 227.639 bits (579), Expect = 1.412e-55 Identity = 310/1377 (22.51%), Postives = 571/1377 (41.47%), Query Frame = 1 Query: 211 IHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNV-DANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQ--TLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYN-QIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYST--ALAIEDINNEPATFSF-NWTVDFVTENSNNISLGQLLLM-TDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLID-KNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNEL-LTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYI--AKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPE-GSQVQFVLNSCKNVECPFYILQNSSIFLNK-SLQVLTENDQLEFEVTVSDILNTNVS--LSLEVTIFRENLAQISMEFKDVMNLPENSPIGS-KVLEIQINFLSNFMPNINCEIFSDGNFFII-VDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVN 4287 + V D N+ P++I LSN V+EN G +VG +S D D DS +V D+ F V + L LD+ET++ V + D ++ I+V D+NE P I ++ + +EN+ +G +G + D D D + + + + +++++ + + E +S + +++ TD + + SE I + +V+E P+D+ L++++ ++EN++ +G LS D D + +++ + + V +L +K+ L++E+ V +++T+ I + DVNE P ++L ++V EN +G+V+G S D + S + F + L+LKD LD+E + + + TD F I + D NE P +++LSN + EN G ++ ++ D D T Y +D + + KL G DHE + +T D S+TF+I + + NE P I N + ++ N +++ D DD D++RF + DL + +LD+E + + + D T I V +VNE P+ +A+ + ++ EN G + + TTD D D Y++ + +FE G L LK+ D+E+ + V + D+ G + I++ D N+ P+ L+ + + G ++ D D+ T++ ++ + + + L +L+ T E + +E+ T TYS +A+ D+N P+ S N +VD EN+ +G L D + + +V ++K++ LD+E+E++ + T D + S + + DVNE PS+I N ++ E + + + + TD D H++ + + + ++V +L L D SLD Y T V++ + Q F I + + ND PT I+ L L+ + +A V+ D D D H ++ F + + + LD+ET + + V D SG S F I + DVNE P ++ +SN +E + G ++ +LS D + G + ++ + F ++ + SL TE+ + EVT +D S ++ V E + IS+ V + +GS ++ + D F ++ D K+ SLD+E+ S + V V + + TI V DV+E +I ++ Sbjct: 371 VTVTPTDVNEGPSDIALSNSSVDEN-AAGVVVGSLSTTDVDAGDSHTYAVD-DARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSN------ASVDENA-AGAVVGSLSTTDVDDGDTHTYAVD--------------DARFEVVGGDLKLKDGVSLDHESESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDISLSNAS-----VDENAAGAVVGSLSTTDVDDGDTHTYAVDDARFEVV----GGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTITVGDVNEGPSDISLSNASVDEN-AAGAVVGTLSTTDVDAGD-----SHTYAVDDARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIA--VGDVNEGPSDIALSNASVDEN-AAGAVVGTLSTTDVDDGDTHSYAVDDARFEVVGGDLKLKDGVSLDHEAESSVAVEVTTTDA--SGATYSETFNIAVGDVNEGPSDI---SLSNAS-----VDENAAGAVVGSLST--TDVDDGDTHTYAVDDARF---------EVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNA-----SVDENAAGAV-VGSLSTTDVDDGDTHTYAVDDA-----RFEVVGG--DLKLKDGVSLDHEAE--SSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDISLSNASVDENAAG-AVAGSLSTSDVDDGDTHSYAVDDARFEVVGGDLKLKNGVSLDHET-------ESSVAVEVTT-----TDASGATYSETFTIAVGDVNEGPSDISLSNASVD---ENAAGAVVGTLSTTDVDAGDSHTYAVDDARFEVVGGDLKLKDGV--------SLDHESESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIA--LSNTSVDENAAGAV-VGSLSTTDVDAGDSHTYAV----------DDARFEVVGGDLKLKDGVSLD-----YNTDPSVDVTVTTTDSAGATYQETFSISVGDTNDAPTDIS-LDNLSVDENAAGA--VVGTLSTTDVDAGDSHTYAVDDARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEDPSDISLSNASVDENA-AGAVVGSLSTTDVDAGDSHTYAVDDAR-----FEVVGGDLKLKDGVSLDHETES-SVAVEVTTTDASGATYSETFTIAVGDVNEGPSDISLSNASVDENAAGAVVGSLSATDVDAGDSHTYA-------VDDARFEVVGGDLKLKDGVSLDHESESSVAVEVTTTDASGATYSE-TFTIAVGDVNEGPSDIALS 1610 HSP 4 Score: 224.172 bits (570), Expect = 1.602e-54 Identity = 275/1209 (22.75%), Postives = 499/1209 (41.27%), Query Frame = 1 Query: 217 VAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNV-DANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI-FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFE---PDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQ--TLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFS--FNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDP----------------LDYETENNFLISFTLID-KNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNEL-LTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYI--AKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSAN 3756 +++ D ND PT+I L N V+EN G++VG +S D D DS +V D+ F V + L LD+ET++ V + D ++ I+V D+NE P I ++ + +EN+ +G +G + D D D + + + + +++++ + + E +S + +++ TD + + SE I + +V+E P+D+ L++++ ++EN++ +G LSA D D + +++ + + V +L +K+ L++ES V +++T+ I + DVNE P + L S+V EN +G+V+G S D ++ ++ F + L+LKD LD+E + + + TD F I + D NE P ++SLSN + EN G ++ ++ D D T Y++D + + KL G DHE + +T D S+TF I + + NE P I + N ++ A V D DD D++RF + DL + +LD+E + + + D T I V +VNE P+ +A+ S ++ EN G + + TTD D D Y++ + +FE G L LK+ D+E+ + V + D+ G + I++ D N+ P+ L+ + ++G ++ D D+ T++ +++ + E+V + D +D E + S A+ + + AT+S F TV V E ++ISL SN S+ + + +V + + + +++ + D LD+ETE++ + T D + S + + DVNE PS+I N ++ E + + + + D D HS+ + + + ++V +L L D SLD + + VE+ D + F I + +VN+GP+ I+ ++ E+A V+ D D D H ++ F + + + LD+E+ + + V D SG S F I + DVNE P + NE + + + A L AN Sbjct: 1313 ISVGDTNDAPTDISLDNLSVDEN-AAGAVVGTLSTTDVDAGDSHTYAVD-DARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEDPSDISLSN------ASVDENA-AGAVVGSLSTTDVDAGDSHTYAVD--------------DARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDISLSNAS-----VDENAAGAVVGSLSATDVDAGDSHTYAVDDARFEVV----GGDLKLKDGVSLDHESESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNSSVDEN-SAGAVVGSVSTTD------VDAGDTHTYAVDDARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIA--VGDVNEGPSDISLSNASVDEN-AAGAVVGSLSTTDVDDGDTHSYSVDDARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDA--SGATYSETFTIAVGDVNEGPSDIS-------------LSNASVDENAAGAVVGSLSTTDVDDGDTHSYSVDDARF---------EVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNS-----SVDENAAGAV-VGSLSTTDVDAGDSHTYAVDDA-----RFEVVGG--DLKLKDGVSLDHETE--SSVAVEVTTTDASGATYSETFNIAVGDVNEGPSDIALSNASVDENAAG-AVVGSLSTADVDDGDTHS------------YAVDD--ARFEVVGGDLKLKDGVSLDHEAES-------------SIAVEVTTTDASGATYSETFTITVGDVNEGPSDISL---------SNASVDENAAGAVVGTLSTTDVDAGDSHTYAVDDARFEVAGGDLKLKNGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIA--LSNASVDENAAGAV-VGSLSTADVDDGDTHSYAV----------DDARFEVVGGDLKLKDGVSLDHETESSVA---VEVTTTD--ASGATYSETFTIAVGDVNEGPSDISLSNA--SVDENA-AGAVVGSLSTTDVDDGDTHSYSVDDARFEVVGGDLKLKDGVSLDHESESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSAGAVDLGATNEDTSVIITSAQLLAN 2382 HSP 5 Score: 191.815 bits (486), Expect = 9.057e-45 Identity = 298/1368 (21.78%), Postives = 560/1368 (40.94%), Query Frame = 1 Query: 235 NDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVK-SDSPFNV-DANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI-FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQ--TLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYN-QIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYST--ALAIEDINNEPATFSF-NWTVDFVTENSNNISLGQLLL--MTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLID-KNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKI---IVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYI--AKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPE-GSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTEND-QLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFII-VDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEI 4278 N P ++LSN +EN G++VG +S +D+ + + + SD+ F V D L L++E + + + D S + V D+NE P+ + + L +EN + G +G+++ DPD + + + TE+R++ + E Q + ++VTD + + V + +V+E P+D+ L++S+ ++EN++ +G LS D D + +++ + + V +L +K+ L++E+ V +++T+ I + DVNE P + L ++V EN +G+V+G S D ++ ++ F + L+LKD LD+E + + + TD F I + D NE P ++SLSN + EN G ++ ++ D D T Y +D + + KL G DHE + +T D S+TF I + + NE P I N + ++ N T++ + D D + D++RF + DL + +LD+E + + + D T I V +VNE P+ +A+ + ++ EN G + TTD D D Y++ + +FE G L LK+ D+E+ + V + D+ G + I++ D N+ P+ L+ + ++G ++ D D+ T+ ++ + + + L +L+ T E + +E+ T TYS +A+ D+N P+ + N +VD EN+ +G L + D + + + V V ++K++ LD+E E++ + T D + S + + DVNE PS+I N ++ E + + + +D D HS+ + +V G++ K+ N SLD + + VE+ D + F I + +VN+GP+ I+ ++ E+A V+ D D D H ++ F + + + LD+E+ + + V D SG S F I + DVNE P ++ +SN +E + G ++ +LS D + G + ++ + F ++ + L + + D ++ VT +D + +++ N A + D +++ EN+ G+ V + + + + D F ++ D K+ SLD+ET S + V V + + TI V DV+E +I Sbjct: 191 NKAPEEVELSNNSFDENAP-GAIVGTLST-----NDAGEHTYEVSDARFEVVDGVLKLRPGLSLNHEAEPSVALTVTVTDDGGLSFTQDFTLIVGDVNEGPESV------DWTPLPFDENVE-GASVGIVHVTDPDNGETFTY----------TISDPRFEVVEQNGRTELRLKDGESLDAE-QGGVPVTVTVTDSGGETATTSVTVTPTDVNEGPSDIALSNSS-----VDENAAGVVVGSLSTTDVDAGDSHTYAVDDARFEVV----GGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNASVDEN-AAGAVVGSLSTTD------VDDGDTHTYAVDDARFEVVGGDLKLKDGVSLDHESESSVAVEVTTTDASGATYSETFTIA--VGDVNEGPSDISLSNASVDEN-AAGAVVGSLSTTDVDDGDTHTYAVDDARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDA--SGATYSETFTITVGDVNEGPSDI---SLSNAS-----VDENAAGAVVGTLSTTDVDAGDSHTYAV--DDARF---------EVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNA-----SVDENAAGAV-VGTLSTTDVDDGDTHSYAVDDA-----RFEVVGG--DLKLKDGVSLDHEAE--SSVAVEVTTTDASGATYSETFNIAVGDVNEGPSDISLSNASVDENAAG-AVVGSLSTTDVDDGDTHTYAVDDARFEVVGGDLKLKDGVSLDHET-------ESSVAVEVTT-----TDASGATYSETFTIAVGDVNEGPSDIALSNASVD---ENAAGAVVGSLSTTDVDDGDTHTYAVDDARFEV-VGGDLKLKDGV--------SLDHEAESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIS--LSNASVDENAAGAV-AGSLSTSDVDDGDTHSYAVDDARFEVVGGDL------KLKNGV------SLDHETESSVA---VEVTTTD--ASGATYSETFTIAVGDVNEGPSDISLSNA--SVDENA-AGAVVGTLSTTDVDAGDSHTYAVDDARFEVVGGDLKLKDGVSLDHESESSVAVEVTTTDASGATYSETFTIAVGDVNEGPSDIALSNTSVDENA-AGAVVGSLSTTDVDAGDSHTYAVDDAR-----FEVV-GGDLKLKDGVSLDYNTDPSVDVTVTTTDSAGATYQETFSISVGDTNDAPTDISL-DNLSVDENAA-GAVVGTLSTTDVD--AGDSHTYAVDDARFEVVGGDLKLKDGVSLDHETESSVAVEVTTTDASGATYSE-TFTIAVGDVNEDPSDI 1419
BLAST of Protocadherin Fat 4 vs. Ensembl Cavefish
Match: ENSAMXT00000003988.2 (FAT atypical cadherin 4 [Source:NCBI gene;Acc:103037566]) HSP 1 Score: 115.546 bits (288), Expect = 6.427e-25 Identity = 160/684 (23.39%), Postives = 301/684 (44.01%), Query Frame = 1 Query: 157 LEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWK--VEENILVGSLVGQISVVDED--LDDSFKCSVKSDSPFNVDANFN-LFTKAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINEAPDKI---YVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIR-IQFELGFNFERQSELYFQISVTDRNNN-SLSEIVKIIIL--NVDENPTDLKLNDSTSNKVLIEENSSNYS-LGELSAIDEDINELYSFQILILHTDSVE--IKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY---FIQLIDVNEAPQGLTL--YPSTVTENIPSGSVIGKFSILDSNL--NSTIEKC--SLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPENLSLSN-NQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEK-DFYIENN--KLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNE 2109 L I +D PK ++V I D ND P L ++ V E+ +GS V QI+ D+D + + + +PF +D + K LDYE + + + I +D+ S+ + E I + D+N+ + Y TT++ + +EN++ GT + ++ +D D + + VS +T + + I+ + ER S +SV+D S S ++I +++++P + KV I E+ S + +SA D D + + + ++ +S+ +N + +A L+ E++ V + A KDQ L +Y + + DVN+ T Y ++ E+ P+GS + S D++L N T+ + T E+F + +L T LD E +Y L +R TD G + + ++ + + D N+ RP + I ENEP G + ++A D D +N T+ YT+ + F+I +N K+ + + D E + YQ+ ++ D G+ + + I ++++ +NP I + +Y F + EN TI+ D + I I S + R L S +I T +D E+ ++++ + + + T + I V+++N+ Sbjct: 206 LLIEVEDKGEPKRYGYLQVNVTIQDINDNPPAFDLDQYQTSVYEDAAIGSSVLQITATDQDEGANSDIRYFLDEGTPFQIDPKAGTVVIKEALDYEVKKEYSLTIHAVDNGVPSLSGRTEATIKLLDVNDNDPVVKFRYFPTTSK--FASVDENAQIGTVVALLTVSDSDSSSA----NGNISVSILGGNEQGHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGRPVSRSSFASLVIFVNDINDHPPIFQ---EAVYKVDISEDVPKGSYIKGVSATDGDSGQNANLRYSLVSGNSLGWFAISENSGLVTSAALLDRETASVVVLNISA-KDQGLQPKISYTKLIVNITDVNDQVPTFTQSSYHVSLVEHSPAGSELLSLSATDTDLGANGTVRFTFDAETPATVQELFRLDTITGKLSTTTELDREDMGSYLLYVRATDAGAPPLHSIAKVNVTLKDINDNRPVFYPVQYFANIKENEPPGSYVTTVSASDPDLGRNGTVRYTITAGDTFKFHINSNTGKITTLVLLDREEKTAYQLQVSATDGGELRSHTHAIVTITVVDTQDNPPIFTQKEYS-----FVMFENVAPNTVIGTISASTVDLNTNITYLIASGDQRGLFAVNSATGHI-----TATSLIDREEQAFYQLKV-VARGGDVTGEALVNITVKDLND 868 HSP 2 Score: 88.1965 bits (217), Expect = 1.140e-16 Identity = 51/150 (34.00%), Postives = 76/150 (50.67%), Query Frame = 1 Query: 5224 SNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS 5658 SN + C C PG+ G S CE +I+ECL + C + C +LV F C C +G CE VN CL + C +G +C++ +CLC SG+ G C+ I+ C +PC G C+ + G+ C+C G CE + + + S Sbjct: 3824 SNRPQQPYVCNCKPGYAG--SLCETDINECLPSPCH-NGGTCHNLVGGFSCSCPEGFTGMACE-RDVNECLSNPCKNGALCQNFPGGFNCLCKSGFAGKTCDSIINYCECNPCFNGGSCQSRVEGYYCHCPFGVFGKHCELNSYGFEELS 3969 HSP 3 Score: 72.7886 bits (177), Expect = 5.676e-12 Identity = 257/1183 (21.72%), Postives = 454/1183 (38.38%), Query Frame = 1 Query: 157 LEILAKDLDVPKNSKLFIIHVAILDAND-PPTNIQLSNWK-VEENILVGSLVGQISVVDEDLD--DSFKCSVKSDSP----FNVDA-NFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEIS-----VTDINE-APDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNF------ERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPT------DLKLNDSTSNKV---LIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPS-----TVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLS--NNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTVF------DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMK-----NFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLY--LKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDANDPPTVAGLNFTMIPSF--------VEKDFIIGK--VNVFDED-NLSTYNQIECSIIK--PLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHT-KIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMT---DY-SNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDP--------LDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEI-FNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPS-LSIQSRFYIQIINVNDGPTAINYLTKLTAIKES 3438 L I AKD P S + + + D ND PP +K + EN+ + + + I+ D D D + S+ +P F++D + +F+ +D E FE+ ++ D + K + VTD N+ P+ I N L A N G+ + + DPD N +E+ D + ++ L ++ + L + + S I + + S+ I IL + P D T KV ++ S ++G L I +I ++ +H +L++ + + E+S Q I L D+N+ P ++P+ TV EN+ G I + + D++ + ++ F I +L RLD E+ Y+L +R D GQ++ +D + + +SD N+ S S + IPE+ G ++A I A D+D N + Y+L+ ++ D+ N + VF D+E + Y +T+ D G +V F++ +N N P T V+ + L + +TV D DD N Q+ + Q I L + LD E +++ + + +NDM FT+ ++ + + +VN+ P + + + I EN + TD D N ++YS+ + +G +L L + +Y + I A D G LS ++V + + D ND PSF +E++ + G + VF D + T QI SI F I +++ + + R + + +Q + G + ++ T + L D+N+ F + V EN ++ L ++ DY SN L S S NED +F LT LD ET++ + + T ID S + S + V + DVN+ S + ++ E +P + A+D D Q +G+ N + +I+ + LL D S NY + ++ D GQP+ LS + + + ++ND P ++ +T I S Sbjct: 1369 LNITAKDNGRPPRSSSIPLVIHVRDFNDNPPVFTPGDIFKSIPENLPLSTSIMTITAHDTDADINGELEYSIVQQTPRGNHFSIDPISGIIFSNGQIDREFSNLFELTVKATDQAVPAEFRKFALKNITVWVTDQNDHVPNFISQNA------LVAEANIVIGSILTTVMAFDPDEGANGEVEYELVKGDSDTFIMDRYSGDIRVASQLVPSKLIYSLTVSATDHGTDRKTSRTELTIILQGTDGPVFSQPKYITILKEGQPPGTNVISLDASSPRGTGTKVEYFIVSVRSGGKAVGRLFTIGRHTG-------VIQTAMELDREHGADLYLLDVYAIETEAS------------QPHTQRAEVEITLQDINDNPP---IFPTDILDVTVQENVGDGFRIMQLTATDADEGPNALVTYTIISGADDSFRIDPESGDLIATKRLDRERRSKYSLLVRADD-GQQS--SDMTVNITVSDVNDHTPKFSRSVYSFDIPEDMAPGSIVAAILASDSDSGVNGEITYSLEEDDGDYTFLLNPVTG--VFNVTQPLDYETQQYYILTVRAVDGGGQASSVRVYFNVLDVNDNR-PAF--------NTSVYSTSISESLTPGSSILTVAASDADDGPNAQLSYSIASGDPQAHFGITTAGV--LQTRKLLDRETQSFYNLVVTVNDMALPPATRFTSTAQVSVILLDVNDCPPVF----TSQKMAYIQENTAVDTVVFTVQATDADSGPNSYVEYSLGGSYGVKFSIDNIDGSVRLVGELDREEMANY--------SLTIVATDKGQPPLSSTMDVTMMVLDVND----------NTPSFSQNIYDIEIEENTLSGTDVLQVFASDADEGTNGQIRFSIAAGNGNSDFRIDSVTGVISVAKLLDRETRASY-SLVVQAADRGSSPRVDRATVNIVLL--DVNDCAPVFELSPYTVRVQENLADLPKNILQVVGRDDDYGSNGQLSYSLSG------------GNEDAAFSLTSSGQLKLIRTLDRETQDRYSLIITAIDSGSPSLSGSATVLVLVDDVNDMVPLFSSSSFHTSITEDAPTGSDVLLVNASDGDVGQNGVITYSLSGGDGQFSINPATGQIITSSLL-DRESR----GNY----QLLVVASDGGQPTPLSSSAMVSVVVTDINDNPPRFHHHPYVTHIPAS 2461 HSP 4 Score: 70.4774 bits (171), Expect = 2.795e-11 Identity = 51/178 (28.65%), Postives = 80/178 (44.94%), Query Frame = 1 Query: 5203 HRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQ----CLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE--FDHFSCKNCSENFGVCLNLKNKNQYC 5706 HR + K + + D C NP NG SC+ + +S I + N Q C C +G CE +N CL S C +G C + SC C G+ G+ C + +++C+ +PC +C++ GF C C+ F G C+ ++ C C N G C + + + YC Sbjct: 3776 HRQSGVKIDSV-DHDPCTHNP--CQNGGSCKRHLSVGPDMMTMESVPVILVSNRPQQPYVCNCKPGYAGSLCET-DINECLPSPCHNGGTCHNLVGGFSCSCPEGFTGMACERDVNECLSNPCKNGALCQNFPGGFNCLCKSGFAGKTCDSIINYCECNPCF-NGGSCQS-RVEGYYC 3947 HSP 5 Score: 68.9366 bits (167), Expect = 7.649e-11 Identity = 133/580 (22.93%), Postives = 243/580 (41.90%), Query Frame = 1 Query: 106 YSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND--PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDS----FKCSVKSDSP---FNVDANFNLFTKAPLDYETQARFEVIIECLDHE---NSSVINKHEISVT--DINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEI--VKIIILNVDENPTDLKLNDSTSNKVLIEENS-SNYSLGEL--SAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQ---ILIFNKTYFIQLIDVNEAPQGLTLYPSTVT-----ENIPSG--SVIGKFSILDSNLNSTIEKCSLQLITFNE---IFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLS--NNQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDP 1725 ++++ PL++E++ I + + +D + ++ +LD ND P N + + + E++ GS + ++V D DD S+ S P F + L T+ LD ETQ+ + +++ D + + ++SV D+N+ P T+++M EN+ T + + D D N Y+E+ + + + +R+ EL + E + I TD+ LS V +++L+V++N N + IEEN+ S + ++ S DE N F I + +S + + + + A+L + +Y +V D+ + T I L+DVN+ L P TV ++P V+G+ SN + S L NE L S QL+L LD E Y+L I D G ++ +++ + D N+ S S + I E+ P G + ++NA D D +N + Y+L + F I ++++ ++ D E+R YQ+ + D G P Sbjct: 1879 FNVTQPLDYETQQYYI---LTVRAVDGGGQASSVRVYFNVLDVNDNRPAFNTSVYSTSISESLTPGSSI--LTVAASDADDGPNAQLSYSIASGDPQAHFGITTAGVLQTRKLLDRETQSFYNLVVTVNDMALPPATRFTSTAQVSVILLDVNDCPPVF----TSQKMAYI-QENTAVDTVVFTVQATDADSGPNSYVEYSLGGS---------YGVKFSIDNIDGSVRLVGEL--DREEMANYSLTIVATDKGQPPLSSTMDVTMMVLDVNDNTPSFSQN---IYDIEIEENTLSGTDVLQVFASDADEGTNGQIRFSIAAGNGNS-DFRIDSVTGVISVAKLLDRETRASYSLVVQAADRGSSPRVDRATVNIVLLDVNDCAPVFELSPYTVRVQENLADLPKNILQVVGRDDDYGSN-----GQLSYSLSGGNEDAAFSLTSSGQLKLIRT--LDRETQDRYSLIITAIDSGSPSLSGSATVLVLVDDVNDMVPLFSSSSFHTSITEDAPTGSDVLLVNASDGDVGQNGVITYSLSGGDGQFSINPATGQIITSSLLDRESRGNYQLLVVASDGGQP 2426 HSP 6 Score: 67.781 bits (164), Expect = 1.484e-10 Identity = 221/1030 (21.46%), Postives = 412/1030 (40.00%), Query Frame = 1 Query: 1369 RLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIP--ENEPIGLLIAIINAQDNDKNSTLVYTLDV----NEKDFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFH-IMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDP--DQNDVIKYSILNCLNCNEKFEFSNGGSKLYL--KESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMI------PSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKP------LKWF------------SILNISQNLEIVTTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNE--LLTDVNSLDVVVS--NYIT--YFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKES----ANINTVLAXXXXXXXXXXXXHQCHGSN--SYFGISNSSIYIAKR-LDYETFTKMETIVVCFDQS---GLNVSSVFQIDI--EDVNE-PPENVKISNDQWNEKSEIGLLIANLSANDPEG---SQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFE-----VTVSDILNTNVSLSLEVTIF----RENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEI-FS----DGNFFIIVD---FKVLLNKSLDYETNSHIMVTVKC 4197 +LDYE T +Y+L I D G + + + + + D N+ + S S+ + EN IG L+ I A D+D S T + N F I + +G++F D+E + Y++ IT DNG P + S I + + N+NP + ++F I EN L + TIT + D D IN ++ + + +++ N F D + N +D E +N FE+ ++ D A+ F K A+ + I + +T+ + NFI+ + + +++ SIL + + E +NG + L +S F + G DI+V + + S + + +S D + T+I P F + +I + E N I P +++F + I ++ ++ TA E D +++ ++ + + ++DIN+ P F + V EN + L TD + +II ++ +I E + T LD E + + + D + + + + + DVN+ + + + E P +A A+D D VNGEI +S+ + + LL V + V +Y T Y+ + + D G + S+ R Y +++VND A N T+I ES ++I TV A + + + + ++FGI+ + + ++ LD ET + +V D + +S Q+ + DVN+ PP E + + ++ + A D + S V++ L V+ + + N ++ S++++ E D+ E + +D +S +++VT+ +N S D+ + EN+ G+ VL++ F S+ N +I FS +GN +D + + K LD ET + + V+ Sbjct: 1253 KLDYEATSSYSLKIIAEDSGSVPLSSSCLLSVSVLDENDNSPSFSKSSMSVDILENMRIGELVVSITATDSDSGSNADITYSIMANNNHGTFSISPS---TGSIFLVRKLDYETQSLYKLNITAKDNGRPPRSSSIPLVIHVRDFNDNPPVFTPG------DIFKSIPENLPLSTSIMTITAHDTDAD--INGEL-----EYSIVQQTPRGNHFSIDPISGIIFSNGQIDREFSNLFELTVKATDQ----AVPAEF----------RKFAL---KNITVWVTDQ---NDHVPNFISQNALVAEANIVIGSILTTVMAFDPDEGANGEVEYELVKGDSDTFIMDRYSG-DIRVASQLVPS---KLIYSLTVSATDHGTDRKTSRTELTIILQGTDGPVFSQPKYI----TILKEGQPPGTNVISLDASSPRGTGTKVEYFIVSVRSGGKAVGRLFTIGRHTGVIQTAMELDREHGADLYLLDVYAIETEASQPHTQRAEVEITLQDINDNPPIFPTDILDVTVQENVGDGFRIMQLTATDADEGPNALVTYTIISGADDSFRID-PESGDLIATKRLDRERRSKYSLLVRADDGQQSSDMTVNITVSDVNDHTPKFSRSVYSFDIPEDMAPGSIVAAILASDSDSG-----------VNGEI-TYSLEEDDGDYTFLLNPVTGVFNVTQPLDYETQQYYILTVRAVDGGGQASSV--RVYFNVLDVNDNRPAFNTSVYSTSISESLTPGSSILTVAASDADDGPNAQLSYSIASGDPQAHFGITTAGVLQTRKLLDRETQSFYNLVVTVNDMALPPATRFTSTAQVSVILLDVNDCPPVFTSQKMAYIQENTAVDTVVFTVQATDADSGPNSYVEYSLGGSYGVK---FSIDN----IDGSVRLVGELDREEMANYSLTIVATDKGQPPLSSTMDVTMMVLDVNDNTPSFSQNIYDI-EIEENTLSGTDVLQV---FASDADEGTNGQIRFSIAAGNGNSDFRIDSVTGVISVAKLLDRETRASYSLVVQA 2212 HSP 7 Score: 67.781 bits (164), Expect = 1.627e-10 Identity = 84/322 (26.09%), Postives = 148/322 (45.96%), Query Frame = 1 Query: 1348 LELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ--IPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTV-----FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVF-HIMENNELEMTFATITVFEPD---FDDKINCQIISDNSRFLVQ-KKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMK---NFTAIMKIFIFVENVNEPPTKLAIDGSREII--INITENIQGYQSIANFITTDPD--QNDVIKYSILN 2250 L L LD E P Y L I V D G+ ++ + I D N+ P L Q + E+ IG + I A D D+ NS + Y LD F I+ +GTV D+E + Y +TI DNG P L+ I++L+ N+N + ++K +Y T F + EN ++ A +TV + D + I+ I+ N + + S + N+ + + LD E+ + + + + ++D + ++ + IFV ++N+ P +E + ++I+E++ I TD D QN ++YS+++ Sbjct: 188 LHLVTTGGLDRELAPFYQLLIEVEDKGEPKRYGYLQVNVTIQDINDNPPAFDLDQYQTSVYEDAAIGSSVLQITATDQDEGANSDIRYFLDEGTP-FQIDPK---AGTVVIKEALDYEVKKEYSLTIHAVDNGVPSLSGRTEATIKLLDVNDN-DPVVKFRYFPTTSKFASVDENAQIGTVVALLTVSDSDSSSANGNISVSILGGNEQGHFEVHTSPVPNLSL--IKVASVLDRERISSYNLTVSVSDNGRPVSRSSFASLVIFVNDINDHPPIF-----QEAVYKVDISEDVPKGSYIKGVSATDGDSGQNANLRYSLVS 497 HSP 8 Score: 65.855 bits (159), Expect = 5.874e-10 Identity = 153/709 (21.58%), Postives = 289/709 (40.76%), Query Frame = 1 Query: 103 EYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND-PPTNIQLSNWKVEENILVGSLVGQISVVDEDLD-DSFKCSVKSDS--PFNVDANFNLFT-KAPLDYETQARFEVIIECLDHENSSVINKH-EISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDE---DINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQ---ILIFNKTYFIQLIDVN-EAPQ-GLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFN-------EIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYI--ENNKLLSGTVF-DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDF-DDKINCQIISDNSR---FLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTA--IMKIF--IFVENVNEPP 2115 E + PL+ E KT SL++ A D P+ S + + +LD ND P ++ + V EN VG V +++ DED ++ SD+ PF+++ + T PL+ E + I + H++ ++ I VTDIN+ + + L E + G+ + + D D N + ++ S S + + K ++R Q G N + F ++ +DR L +I+ VD N S+ + + +L +++A D+ +N + I ++ S K W+ ++ L + + V Y + KD+ +L T I + + N P+ + + V+E++ G+ I S D + + + LIT+N +F++++ L LDYEK + L I TD G + + ++++D N+ P + EN P G ++ +NA D D NS + Y + ++ D +I N +++ F D+E + Y +T+ F+ D + +I++ +NE + QY F + E + + D DD + +I SR F + KK+ + + LD E+ + + + + I ++F I + + N+PP Sbjct: 2707 EIRTTRPLDRE-KTAQYSLKVKATDRGAPQKSTAVSVVINVLDVNDNAPRFSKIFSATVPENAPVGYTVTRVTTTDEDTGANAVSRYTISDTSLPFSINPSTGDITISRPLNREDTDHY--IAKVSAHDSGWTVSTDVTIFVTDINDNAPRF----SKPSYYLEYPELTDVGSLVTKVSATDLDEGFNGKIFYFIRSQ--SENFRINSSTGEIFVK--QQLRYQNSTGHNNANINRHSFIVTASDRGIKPLMSETTVIVNIVDSNDNPPTFESSSYFTPVTKSVKVGTNLIKVTAHDKKDFGVNSEIEYVISGGNSSSKFRLDKQTGWVTVASSLTSDINKV-YLLEITAKDKGNPVLSDKATLKIAVTEENHHTPEFSQSQVIAAVSESLTVGTAIRTLSARDKDKDKQMNG----LITYNISSGNDDGLFVVNEKTGVLSLAKPLDYEKKQKHELRISATDGGWIAKTSYVTVNIQVTDVNDNPPMFEPDEYFPVVQENVPSGTIVVKLNATDKDSSSNSVMAYVIQSSDSDLFIIDPNTGVITTQGFLDYEAKQVYHLTVKAFNVPDEERCSFANVNIQLKGANEYVPRFVSKQY-----YFEVSEAAPKGTMVGEVFASDRDLGDDGVVYYLIFGRSRRKGFGINKKTG-------QIYVTGPLDREKEEKISLKVLAKNAGSIRGADIDEVFVNITILDANDPP 3387 HSP 9 Score: 59.3066 bits (142), Expect = 5.827e-8 Identity = 143/672 (21.28%), Postives = 270/672 (40.18%), Query Frame = 1 Query: 793 FQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDED----INELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYF---IQLIDVNEAPQGLTL--YPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANER-PENLSLSNN-QIPENEPIGLLIAIINAQDND-KNSTLVYTL---DVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPK-LNVSKTF-DIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEI-KNIFQYDLTINQT-----LDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNE-PPTKLAIDGSREIIINITENIQGYQSIANFITTDPD---QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLK-WFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKS 2706 +I+ D+ N LS+ + I +EN + + S + E + ++ LSA D+D +N L ++ I + D + + ++ + + L+YE + + A D I +Y IQ+ DVN+ P Y V EN+PSG+++ K + D + +S + + +++F+I + LDYE Y+L ++ + E + + +++ ANE P +S ++ E P G ++ + A D D + +VY L K F I + ++ D E + + + G + ++ + F +I IL++N+ P E++ + + L V D D + SRF ++ KN F + Q LD E + + + D + T + + +E++N+ PT + G + EN + + + DPD YS+L+ + F ++ G L S+ D E + V+I+ DSG +S V + I D ND P+ + + + F G + + + ++ +CS+I P FSI + S NL + R D F D+ ++ + H+ + S Sbjct: 3040 LEITAKDKGNPVLSDKATLKIAVTEENHHTPEFSQSQVIAAVSESLTVGTAIRTLSARDKDKDKQMNGLITYNISSGNDDGLFVVNEKTGVLSLAKPLDYEKKQKHELRISA-TDGGWIAKTSYVTVNIQVTDVNDNPPMFEPDEYFPVVQENVPSGTIVVKLNATDKDSSSNSVMAYVIQSSDSDLFIIDPNTGVITTQGFLDYEAKQVYHLTVKAFNVPDEERCSFANVNIQLKGANEYVPRFVSKQYYFEVSEAAPKGTMVGEVFASDRDLGDDGVVYYLIFGRSRRKGFGINKKTGQIYVTGPLDREKEEKISLKVLAKNAGSIRGADIDEVFVNITILDANDPPVFT--------QELYDVQVSEGLSPGGLVTFVSAEDSDS------VPSWSRFTYSVTTDREKNAFTINPQTGQVSVAAELDRETTPVYNLTLLAIDSGSPAATGTATLIVTLEDINDNGPTLVTTTG------EVMENQRAGTPVMTLNSVDPDLAPNQGPFSYSLLSTGSAVTYFTLTSSGE---LSTSREIDREQISDFYLSVVIK--DSGVPQMSSTGTVHVKINDQNDNPSQP-RSVEIFVHYFGNMFPGGSLGIVKPQDPDIHDTFQCSLIPPAASLFSIPSGSCNLN---SNARSTDGTF-DVSVRSNDGVHSPVNS 3680 HSP 10 Score: 58.151 bits (139), Expect = 1.478e-7 Identity = 117/540 (21.67%), Postives = 223/540 (41.30%), Query Frame = 1 Query: 1894 DDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQT-------------LDYEQNNYFEINIEINDM---KNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND-PPTVAGLNFTMIPSFVEKD------FIIGKVNVFDEDNLSTYNQIECSIIKP--LKWFSI-LNISQNLEIVTTATRFIDEKF--IDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFN-WTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDP--LDYETENNFLISFTLIDKNSNQSIN---LKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQ----IHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVND 3387 D I + + +VQ + K F+ D+T+N + LD E ++++ IE+ D K + +++ + ++++N+ P +D + ++ E+ S+ TD D+ N I+Y L+ F+ + +KE+ DYE + K+ + I A+D+G LS E I + D ND P V F F D ++ + V D D+ S I SI+ F + + NL ++ A+ E+ ++ + +NG +S+ S + + DIN+ P F + VD ++E+ S + + TD S Q + ++ N++ +NS ++T LD ET + +++ + D+ I+ L V I DVN+ ++++ E SP + + ATD D +FD + E+F + + +L T + +Y+ Y + D G P L ++ + + ++ND Sbjct: 149 DADIGSNGVDHTTYRIVQGNEQRK--FRLDITVNPSGEGAFLHLVTTGGLDRELAPFYQLLIEVEDKGEPKRY-GYLQVNVTIQDINDNPPAFDLD---QYQTSVYEDAAIGSSVLQITATDQDEGANSDIRY----FLDEGTPFQIDPKAGTVVIKEA--LDYE--VKKEYSLTIHAVDNGVPSLSGRTEATIKLLDVNDNDPVVKFRYFPTTSKFASVDENAQIGTVVALLTVSDSDSSSANGNISVSILGGNEQGHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGRPVSRSSFASLVIFVNDINDHPPIFQEAVYKVD-ISEDVPKGSYIKGVSATD--GDSGQNANLRYSLVSGNSLGWFAISENSGLVTSAALLDRETASVVVLNISAKDQGLQPKISYTKLIVNITDVNDQVPTFTQSSYHVSLVEHSPAGSELLSLSATDTDLGANGTVRFTFDAETPATVQELFR---LDTITGKLSTTTELDREDMGSYLLY----VRATDAGAPPLHSIAKVNVTLKDIND 664 HSP 11 Score: 57.3806 bits (137), Expect = 2.365e-7 Identity = 217/1084 (20.02%), Postives = 436/1084 (40.22%), Query Frame = 1 Query: 88 ESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND-------PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVD-ANFNLFTKAPLDYETQARFEVIIECLDH---ENSSVINKHEISVTDINE-AP--DKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDIN-ELYSF-----QILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQI--LIFNKTYFIQLIDVNEAPQGL--TLYPSTVTENIPSGSVIGKFSILDS---NLNSTIEKCSLQLITFNEIFLISQFQLELKDN-----TRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDNDK----NSTLVYTLDV-NEKDFYIENNK---LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQII-----SDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD-QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDS-GGLSID-LEVPISIQDANDPPT-VAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSII--KPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKS----SIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQ---SINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPD 3153 + + E S+ PL++E+ + L I A+D P S I + +LD ND P + ++ + +LV S + Q S + LD + K +S F+++ A + T PLD E A++ + ++ D + S+ ++ I+V D+N+ AP KI+ T EN+ G + + D D T + VS +L + +I I L N E ++S D + ++S V I + ++++N + + S + + +DE N +++ F + +++ + EI K +L + S N + + F+V A I L+ T + ++D N+ P + Y + VT+++ G+ + K + D +NS IE +I+ S+F+L+ + + L + Y L I D G + + + +++ N S S + E+ +G I ++A+D DK N + Y + N+ ++ N K L D+E + +++ I+ D G T +I++ + N+NP + D+Y F +++ N T + + D D N + SD+ F++ + + +T LDYE + + ++ ++ + + + I ++ NE + S++ ++E + +D D +D + Y ++ + + F + ++Y+ D E +KVL + S G ID + V I+I DANDPP L + + ++ V+ D D++ ++++ S+ + F+I + + + R + ++ + ++G + + T + + +EDIN+ T V E N G ++ + + L ++ S++ S + + +D E ++F +S + D Q + + V+I D N+ PS+ +S E + F P + DPD Sbjct: 2598 DQLSGELSLKAPLDYENIEKYV-LWIEARDQSFPPYSAYEKIEITVLDVNDNNPVFEKEPFHAEILENLSPQRVLVVSALDQDSGPNGQLDYTIIDGNKENS-FSINRATGEIRTTRPLDREKTAQYSLKVKATDRGAPQKSTAVSV-VINVLDVNDNAPRFSKIFS--------ATVPENAPVGYTVTRVTTTDED--------TGANAVSRYTISDTSLPFSINPSTGDITISRPL--NREDTDHYIAKVSAHD-SGWTVSTDVTIFVTDINDNAPRFSKPSYYLEYPELTDVGSLVTKVSATDLDEGFNGKIFYFIRSQSENFRINSSTGEIFVKQQLRYQNSTGHNNANINRHSFIVTASDRGIKPLMSETTVIVNIVDSNDNPPTFESSSYFTPVTKSVKVGTNLIKVTAHDKKDFGVNSEIE----YVISGGNSS--SKFRLDKQTGWVTVASSLTSDINKVYLLEITAKDKGNPVLSDKATLKIAVTEENHHTPEFSQSQVIAAVSESLTVGTAIRTLSARDKDKDKQMNGLITYNISSGNDDGLFVVNEKTGVLSLAKPLDYEKKQKHELRISATDGGWIAKTSYVTVNIQVTDVNDNPPMFEPDEY------FPVVQENVPSGTIV-VKLNATDKDSSSNSVMAYVIQSSDSDLFIIDPNTGV-------ITTQGFLDYEAKQVYHLTVKAFNVPDEERCSFANVNIQLKGANEYVPRFV---SKQYYFEVSEAAPKGTMVGEVFASDRDLGDDGVVYYLIFGRSRRKGFGINKKTGQIYVTGP--LDREKEEKISLKVLAKNAGSIRGADIDEVFVNITILDANDPPVFTQELYDVQVSEGLSPGGLVTFVSAEDSDSVPSWSRFTYSVTTDREKNAFTINPQTGQVSVAAELDRETTPVY-NLTLLAIDSG-SPAATGTATLIVTLEDINDNGPTL-----VTTTGEVMENQRAGTPVMTLNSVDPDLAPNQGPFSYSLLSTGSAVTYFTLTSSGELSTSREIDREQISDFYLSVVIKDSGVPQMSSTGTVHVKINDQNDNPSQPRSVEIFVHYFGNMFPGGSLGIVKPQDPD 3627
BLAST of Protocadherin Fat 4 vs. Ensembl Cavefish
Match: ENSAMXT00000031516.1 (FAT atypical cadherin 4 [Source:NCBI gene;Acc:103037566]) HSP 1 Score: 114.775 bits (286), Expect = 1.108e-24 Identity = 160/684 (23.39%), Postives = 301/684 (44.01%), Query Frame = 1 Query: 157 LEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWK--VEENILVGSLVGQISVVDED--LDDSFKCSVKSDSPFNVDANFN-LFTKAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINEAPDKI---YVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIR-IQFELGFNFERQSELYFQISVTDRNNN-SLSEIVKIIIL--NVDENPTDLKLNDSTSNKVLIEENSSNYS-LGELSAIDEDINELYSFQILILHTDSVE--IKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY---FIQLIDVNEAPQGLTL--YPSTVTENIPSGSVIGKFSILDSNL--NSTIEKC--SLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPENLSLSN-NQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEK-DFYIENN--KLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNE 2109 L I +D PK ++V I D ND P L ++ V E+ +GS V QI+ D+D + + + +PF +D + K LDYE + + + I +D+ S+ + E I + D+N+ + Y TT++ + +EN++ GT + ++ +D D + + VS +T + + I+ + ER S +SV+D S S ++I +++++P + KV I E+ S + +SA D D + + + ++ +S+ +N + +A L+ E++ V + A KDQ L +Y + + DVN+ T Y ++ E+ P+GS + S D++L N T+ + T E+F + +L T LD E +Y L +R TD G + + ++ + + D N+ RP + I ENEP G + ++A D D +N T+ YT+ + F+I +N K+ + + D E + YQ+ ++ D G+ + + I ++++ +NP I + +Y F + EN TI+ D + I I S + R L S +I T +D E+ ++++ + + + T + I V+++N+ Sbjct: 206 LLIEVEDKGEPKRYGYLQVNVTIQDINDNPPAFDLDQYQTSVYEDAAIGSSVLQITATDQDEGANSDIRYFLDEGTPFQIDPKAGTVVIKEALDYEVKKEYSLTIHAVDNGVPSLSGRTEATIKLLDVNDNDPVVKFRYFPTTSK--FASVDENAQIGTVVALLTVSDSDSSSA----NGNISVSILGGNEQGHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGRPVSRSSFASLVIFVNDINDHPPIFQ---EAVYKVDISEDVPKGSYIKGVSATDGDSGQNANLRYSLVSGNSLGWFAISENSGLVTSAALLDRETASVVVLNISA-KDQGLQPKISYTKLIVNITDVNDQVPTFTQSSYHVSLVEHSPAGSELLSLSATDTDLGANGTVRFTFDAETPATVQELFRLDTITGKLSTTTELDREDMGSYLLYVRATDAGAPPLHSIAKVNVTLKDINDNRPVFYPVQYFANIKENEPPGSYVTTVSASDPDLGRNGTVRYTITAGDTFKFHINSNTGKITTLVLLDREEKTAYQLQVSATDGGELRSHTHAIVTITVVDTQDNPPIFTQKEYS-----FVMFENVAPNTVIGTISASTVDLNTNITYLIASGDQRGLFAVNSATGHI-----TATSLIDREEQAFYQLKV-VARGGDVTGEALVNITVKDLND 868 HSP 2 Score: 71.633 bits (174), Expect = 1.158e-11 Identity = 256/1183 (21.64%), Postives = 455/1183 (38.46%), Query Frame = 1 Query: 157 LEILAKDLDVPKNSKLFIIHVAILDAND-PPTNIQLSNWK-VEENILVGSLVGQISV--VDEDLDDSFKCSVKSDSP----FNVDA-NFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEIS-----VTDINE-APDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNF------ERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPT------DLKLNDSTSNKV---LIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPS-----TVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLS--NNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTVF------DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMK-----NFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLY--LKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDANDPPTVAGLNFTMIPSF--------VEKDFIIGK--VNVFDED-NLSTYNQIECSIIK--PLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHT-KIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMT---DY-SNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDP--------LDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEI-FNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPS-LSIQSRFYIQIINVNDGPTAINYLTKLTAIKES 3438 L I AKD P S + + + D ND PP +K + EN+ + + + I+ D D++ + S+ +P F++D + +F+ +D E FE+ ++ D + K + VTD N+ P+ I N L A N G+ + + DPD N +E+ D + ++ L ++ + L + + S I + + S+ I IL + P D T KV ++ S ++G L I +I ++ +H +L++ + + E+S Q I L D+N+ P ++P+ TV EN+ G I + + D++ + ++ F I +L RLD E+ Y+L +R D GQ++ +D + + +SD N+ S S + IPE+ G ++A I A D+D N + Y+L+ ++ D+ N + VF D+E + Y +T+ D G +V F++ +N N P T V+ + L + +TV D DD N Q+ + Q I L + LD E +++ + + +NDM FT+ ++ + + +VN+ P + + + I EN + TD D N ++YS+ + +G +L L + +Y + I A D G LS ++V + + D ND PSF +E++ + G + VF D + T QI SI F I +++ + + R + + +Q + G + ++ T + L D+N+ F + V EN ++ L ++ DY SN L S S NED +F LT LD ET++ + + T ID S + S + V + DVN+ S + ++ E +P + A+D D Q +G+ N + +I+ + LL D S NY + ++ D GQP+ LS + + + ++ND P ++ +T I S Sbjct: 1369 LNITAKDNGRPPRSSSIPLVIHVRDFNDNPPVFTPGDIFKSIPENLPLSTSIMTITAHDTDADINGELEYSIVQQTPRGNHFSIDPISGIIFSNGQIDREFSNLFELTVKATDQAVPAEFRKFALKNITVWVTDQNDHVPNFISQNA------LVAEANIVIGSILTTVMAFDPDEGANGEVEYELVKGDSDTFIMDRYSGDIRVASQLVPSKLIYSLTVSATDHGTDRKTSRTELTIILQGTDGPVFSQPKYITILKEGQPPGTNVISLDASSPRGTGTKVEYFIVSVRSGGKAVGRLFTIGRHTG-------VIQTAMELDREHGADLYLLDVYAIETEAS------------QPHTQRAEVEITLQDINDNPP---IFPTDILDVTVQENVGDGFRIMQLTATDADEGPNALVTYTIISGADDSFRIDPESGDLIATKRLDRERRSKYSLLVRADD-GQQS--SDMTVNITVSDVNDHTPKFSRSVYSFDIPEDMAPGSIVAAILASDSDSGVNGEITYSLEEDDGDYTFLLNPVTG--VFNVTQPLDYETQQYYILTVRAVDGGGQASSVRVYFNVLDVNDNR-PAF--------NTSVYSTSISESLTPGSSILTVAASDADDGPNAQLSYSIASGDPQAHFGITTAGV--LQTRKLLDRETQSFYNLVVTVNDMALPPATRFTSTAQVSVILLDVNDCPPVF----TSQKMAYIQENTAVDTVVFTVQATDADSGPNSYVEYSLGGSYGVKFSIDNIDGSVRLVGELDREEMANY--------SLTIVATDKGQPPLSSTMDVTMMVLDVND----------NTPSFSQNIYDIEIEENTLSGTDVLQVFASDADEGTNGQIRFSIAAGNGNSDFRIDSVTGVISVAKLLDRETRASY-SLVVQAADRGSSPRVDRATVNIVLL--DVNDCAPVFELSPYTVRVQENLADLPKNILQVVGRDDDYGSNGQLSYSLSG------------GNEDAAFSLTSSGQLKLIRTLDRETQDRYSLIITAIDSGSPSLSGSATVLVLVDDVNDMVPLFSSSSFHTSITEDAPTGSDVLLVNASDGDVGQNGVITYSLSGGDGQFSINPATGQIITSSLL-DRESR----GNY----QLLVVASDGGQPTPLSSSAMVSVVVTDINDNPPRFHHHPYVTHIPAS 2461 HSP 3 Score: 71.633 bits (174), Expect = 1.270e-11 Identity = 47/163 (28.83%), Postives = 74/163 (45.40%), Query Frame = 1 Query: 5203 HRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQ----CLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIF---CEFDHFSCKNCS 5658 HR + K + + D C NP NG SC+ + +S I + N Q C C +G CE +N CL S C +G C + SC C G+ G+ C + +++C+ +PC +C++ GF C C+ F G+F CE + + + S Sbjct: 3776 HRQSGVKIDSV-DHDPCTHNP--CQNGGSCKRHLSVGPDMMTMESVPVILVSNRPQQPYVCNCKPGYAGSLCET-DINECLPSPCHNGGTCHNLVGGFSCSCPEGFTGMACERDVNECLSNPCKNGALCQNFPGGFNCLCKSGFAGVFGKHCELNSYGFEELS 3934 HSP 4 Score: 69.707 bits (169), Expect = 3.908e-11 Identity = 206/949 (21.71%), Postives = 352/949 (37.09%), Query Frame = 1 Query: 3232 VNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSY----------FGISNSS--IYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIE--DVNEPPENVKISNDQW----NEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSS---IFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIF------RENLAQISMEFKDV-------------MNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKSLDY-ETNSHIMVTVKCFQNK-----LQILKKLSTTINVTDVDEPLKEIIVNIT--DS--------------IQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTL-PLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAXXXXXXXXXXXXEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDL--NQ---MHDIMIQYPANKYFYIINCCDLMT-QNLEYAWTGPLNASFIITDNGIPPMKSIFNISFNFIESKGEISATNRLINITDK------ANTLIGILKYSLSNSDDISFILEEVPDNA--FSIIKDELWLTKDADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFNSNKCHR-NATCKSNELNDEFQCF---CNPGFVGNGSSCEEIDECLFN---FCLGDSSRC-------IDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSD------CVHGICRDDNSCL-------------------------------CLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKN 5691 V + L +D+N + + +EI +D G P LS ++ I + N + + A+ ES + T AI + D D Q +G +Y F ++ + + +AK LDYE K E + D + +S ++I+ DVN+ P D++ E G ++ L+A D + S + Y++Q+S ++ + V+T L++E L V F R + A ++++ K + E +P G+ V E+ F S+ ++ DG + ++ F K + I VT + K L++L K + +I D+DE + VNIT D+ + EGL + + +D + S F S+ +KN T+ P ++ L Y + L +I+ G ++ + L + LED ND LV +++ G+ + L +D DL NQ + ++ A YF + + +L T + ++ S +I D+G+P M S + I + + + R + I +GI+K + D +F +P A FSI L +A T + +RS D + P++ N+R+ VG S +++ R NA SN L D + F N G G+ + N F + R + FQ + EVL +K D C H C++ SC C G+ G C I++C+ PC+ G C + + GF C+C + FTG+ CE D C N +N +C N Sbjct: 3026 VASSLTSDINKV----------YLLEITAKDKGNPVLSDKATLKIAVTEENHHTPEFSQSQVIAAVSESLTVGT--AIRTLSARDKDKDKQMNGLITYNISSGNDDGLFVVNEKTGVLSLAKPLDYEKKQKHELRISATDGGWIAKTSYVTVNIQVTDVNDNPP--MFEPDEYFPVVQENVPSGTIVVKLNATDKDSSSNSVMA----------YVIQSSDSDLFIIDPNTGVITTQGFLDYEA--------KQVYHLTVKAFNVPDEERCSFANVNIQLKGANEYVPRFVSKQYYFEVSEAAPKGTMVGEV---FASDR------DLGDDGVVYYLI-FGRSRRKGFGINKKTGQIYVTGPLDREKEEKISLKVLAKNAGSIRGADIDE----VFVNITILDANDPPVFTQELYDVQVSEGLSPGGLVTFVSAEDSD---SVPSWSRFTYSVTTDREKNAFTINPQTGQVSVAAELDRETTPVYNLTL----LAIDSGSPAATGTATLIVTLEDINDNGPTLVTTTGEVMENQRA--GTPVMTLNSVDPDLAPNQGPFSYSLLSTGSAVTYFTLTSSGELSTSREIDREQISDFYLSVVIKDSGVPQMSSTGTVHVK-INDQNDNPSQPRSVEIFVHYFGNMFPGGSLGIVKPQDPDIHD-TFQCSLIPPAASLFSIPSGSCNLNSNARSTDGT-FDVSVRSNDG-VHSPVNS-NVRVFFVGFSNATVDNSILIRLNAQSVSNFLTDHYLSFLHIANSQLAGLGTGVQLYGAFELNNQTFLMAAVKRGHGQYVNPSGVATFFQSIK---------EVLHRQSGVKIDSVDHDPCTHNPCQNGGSCKRHLSVGPDMMTMESVPVILVSNRPQQPYVCNCKPGYAGSLCETDINECLPSPCHNGGTCHNLVGGFSCSCPEGFTGMACERDVNECLSNPCKNGALCQNFPG 3905 HSP 5 Score: 68.5514 bits (166), Expect = 1.069e-10 Identity = 133/580 (22.93%), Postives = 243/580 (41.90%), Query Frame = 1 Query: 106 YSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND--PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDS----FKCSVKSDSP---FNVDANFNLFTKAPLDYETQARFEVIIECLDHE---NSSVINKHEISVT--DINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEI--VKIIILNVDENPTDLKLNDSTSNKVLIEENS-SNYSLGEL--SAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQ---ILIFNKTYFIQLIDVNEAPQGLTLYPSTVT-----ENIPSG--SVIGKFSILDSNLNSTIEKCSLQLITFNE---IFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLS--NNQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDP 1725 ++++ PL++E++ I + + +D + ++ +LD ND P N + + + E++ GS + ++V D DD S+ S P F + L T+ LD ETQ+ + +++ D + + ++SV D+N+ P T+++M EN+ T + + D D N Y+E+ + + + +R+ EL + E + I TD+ LS V +++L+V++N N + IEEN+ S + ++ S DE N F I + +S + + + + A+L + +Y +V D+ + T I L+DVN+ L P TV ++P V+G+ SN + S L NE L S QL+L LD E Y+L I D G ++ +++ + D N+ S S + I E+ P G + ++NA D D +N + Y+L + F I ++++ ++ D E+R YQ+ + D G P Sbjct: 1879 FNVTQPLDYETQQYYI---LTVRAVDGGGQASSVRVYFNVLDVNDNRPAFNTSVYSTSISESLTPGSSI--LTVAASDADDGPNAQLSYSIASGDPQAHFGITTAGVLQTRKLLDRETQSFYNLVVTVNDMALPPATRFTSTAQVSVILLDVNDCPPVF----TSQKMAYI-QENTAVDTVVFTVQATDADSGPNSYVEYSLGGS---------YGVKFSIDNIDGSVRLVGEL--DREEMANYSLTIVATDKGQPPLSSTMDVTMMVLDVNDNTPSFSQN---IYDIEIEENTLSGTDVLQVFASDADEGTNGQIRFSIAAGNGNS-DFRIDSVTGVISVAKLLDRETRASYSLVVQAADRGSSPRVDRATVNIVLLDVNDCAPVFELSPYTVRVQENLADLPKNILQVVGRDDDYGSN-----GQLSYSLSGGNEDAAFSLTSSGQLKLIRT--LDRETQDRYSLIITAIDSGSPSLSGSATVLVLVDDVNDMVPLFSSSSFHTSITEDAPTGSDVLLVNASDGDVGQNGVITYSLSGGDGQFSINPATGQIITSSLLDRESRGNYQLLVVASDGGQP 2426 HSP 6 Score: 67.3958 bits (163), Expect = 2.164e-10 Identity = 221/1030 (21.46%), Postives = 412/1030 (40.00%), Query Frame = 1 Query: 1369 RLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIP--ENEPIGLLIAIINAQDNDKNSTLVYTLDV----NEKDFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFH-IMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDP--DQNDVIKYSILNCLNCNEKFEFSNGGSKLYL--KESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMI------PSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKP------LKWF------------SILNISQNLEIVTTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNE--LLTDVNSLDVVVS--NYIT--YFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKES----ANINTVLAXXXXXXXXXXXXHQCHGSN--SYFGISNSSIYIAKR-LDYETFTKMETIVVCFDQS---GLNVSSVFQIDI--EDVNE-PPENVKISNDQWNEKSEIGLLIANLSANDPEG---SQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFE-----VTVSDILNTNVSLSLEVTIF----RENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEI-FS----DGNFFIIVD---FKVLLNKSLDYETNSHIMVTVKC 4197 +LDYE T +Y+L I D G + + + + + D N+ + S S+ + EN IG L+ I A D+D S T + N F I + +G++F D+E + Y++ IT DNG P + S I + + N+NP + ++F I EN L + TIT + D D IN ++ + + +++ N F D + N +D E +N FE+ ++ D A+ F K A+ + I + +T+ + NFI+ + + +++ SIL + + E +NG + L +S F + G DI+V + + S + + +S D + T+I P F + +I + E N I P +++F + I ++ ++ TA E D +++ ++ + + ++DIN+ P F + V EN + L TD + +II ++ +I E + T LD E + + + D + + + + + DVN+ + + + E P +A A+D D VNGEI +S+ + + LL V + V +Y T Y+ + + D G + S+ R Y +++VND A N T+I ES ++I TV A + + + + ++FGI+ + + ++ LD ET + +V D + +S Q+ + DVN+ PP E + + ++ + A D + S V++ L V+ + + N ++ S++++ E D+ E + +D +S +++VT+ +N S D+ + EN+ G+ VL++ F S+ N +I FS +GN +D + + K LD ET + + V+ Sbjct: 1253 KLDYEATSSYSLKIIAEDSGSVPLSSSCLLSVSVLDENDNSPSFSKSSMSVDILENMRIGELVVSITATDSDSGSNADITYSIMANNNHGTFSISPS---TGSIFLVRKLDYETQSLYKLNITAKDNGRPPRSSSIPLVIHVRDFNDNPPVFTPG------DIFKSIPENLPLSTSIMTITAHDTDAD--INGEL-----EYSIVQQTPRGNHFSIDPISGIIFSNGQIDREFSNLFELTVKATDQ----AVPAEF----------RKFAL---KNITVWVTDQ---NDHVPNFISQNALVAEANIVIGSILTTVMAFDPDEGANGEVEYELVKGDSDTFIMDRYSG-DIRVASQLVPS---KLIYSLTVSATDHGTDRKTSRTELTIILQGTDGPVFSQPKYI----TILKEGQPPGTNVISLDASSPRGTGTKVEYFIVSVRSGGKAVGRLFTIGRHTGVIQTAMELDREHGADLYLLDVYAIETEASQPHTQRAEVEITLQDINDNPPIFPTDILDVTVQENVGDGFRIMQLTATDADEGPNALVTYTIISGADDSFRID-PESGDLIATKRLDRERRSKYSLLVRADDGQQSSDMTVNITVSDVNDHTPKFSRSVYSFDIPEDMAPGSIVAAILASDSDSG-----------VNGEI-TYSLEEDDGDYTFLLNPVTGVFNVTQPLDYETQQYYILTVRAVDGGGQASSV--RVYFNVLDVNDNRPAFNTSVYSTSISESLTPGSSILTVAASDADDGPNAQLSYSIASGDPQAHFGITTAGVLQTRKLLDRETQSFYNLVVTVNDMALPPATRFTSTAQVSVILLDVNDCPPVFTSQKMAYIQENTAVDTVVFTVQATDADSGPNSYVEYSLGGSYGVK---FSIDN----IDGSVRLVGELDREEMANYSLTIVATDKGQPPLSSTMDVTMMVLDVNDNTPSFSQNIYDI-EIEENTLSGTDVLQV---FASDADEGTNGQIRFSIAAGNGNSDFRIDSVTGVISVAKLLDRETRASYSLVVQA 2212 HSP 7 Score: 67.3958 bits (163), Expect = 2.182e-10 Identity = 84/322 (26.09%), Postives = 148/322 (45.96%), Query Frame = 1 Query: 1348 LELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQ--IPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTV-----FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVF-HIMENNELEMTFATITVFEPD---FDDKINCQIISDNSRFLVQ-KKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMK---NFTAIMKIFIFVENVNEPPTKLAIDGSREII--INITENIQGYQSIANFITTDPD--QNDVIKYSILN 2250 L L LD E P Y L I V D G+ ++ + I D N+ P L Q + E+ IG + I A D D+ NS + Y LD F I+ +GTV D+E + Y +TI DNG P L+ I++L+ N+N + ++K +Y T F + EN ++ A +TV + D + I+ I+ N + + S + N+ + + LD E+ + + + + ++D + ++ + IFV ++N+ P +E + ++I+E++ I TD D QN ++YS+++ Sbjct: 188 LHLVTTGGLDRELAPFYQLLIEVEDKGEPKRYGYLQVNVTIQDINDNPPAFDLDQYQTSVYEDAAIGSSVLQITATDQDEGANSDIRYFLDEGTP-FQIDPK---AGTVVIKEALDYEVKKEYSLTIHAVDNGVPSLSGRTEATIKLLDVNDN-DPVVKFRYFPTTSKFASVDENAQIGTVVALLTVSDSDSSSANGNISVSILGGNEQGHFEVHTSPVPNLSL--IKVASVLDRERISSYNLTVSVSDNGRPVSRSSFASLVIFVNDINDHPPIF-----QEAVYKVDISEDVPKGSYIKGVSATDGDSGQNANLRYSLVS 497 HSP 8 Score: 65.0846 bits (157), Expect = 9.878e-10 Identity = 153/709 (21.58%), Postives = 289/709 (40.76%), Query Frame = 1 Query: 103 EYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND-PPTNIQLSNWKVEENILVGSLVGQISVVDEDLD-DSFKCSVKSDS--PFNVDANFNLFT-KAPLDYETQARFEVIIECLDHENSSVINKH-EISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDE---DINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQ---ILIFNKTYFIQLIDVN-EAPQ-GLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFN-------EIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYI--ENNKLLSGTVF-DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDF-DDKINCQIISDNSR---FLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTA--IMKIF--IFVENVNEPP 2115 E + PL+ E KT SL++ A D P+ S + + +LD ND P ++ + V EN VG V +++ DED ++ SD+ PF+++ + T PL+ E + I + H++ ++ I VTDIN+ + + L E + G+ + + D D N + ++ S S + + K ++R Q G N + F ++ +DR L +I+ VD N S+ + + +L +++A D+ +N + I ++ S K W+ ++ L + + V Y + KD+ +L T I + + N P+ + + V+E++ G+ I S D + + + LIT+N +F++++ L LDYEK + L I TD G + + ++++D N+ P + EN P G ++ +NA D D NS + Y + ++ D +I N +++ F D+E + Y +T+ F+ D + +I++ +NE + QY F + E + + D DD + +I SR F + KK+ + + LD E+ + + + + I ++F I + + N+PP Sbjct: 2707 EIRTTRPLDRE-KTAQYSLKVKATDRGAPQKSTAVSVVINVLDVNDNAPRFSKIFSATVPENAPVGYTVTRVTTTDEDTGANAVSRYTISDTSLPFSINPSTGDITISRPLNREDTDHY--IAKVSAHDSGWTVSTDVTIFVTDINDNAPRF----SKPSYYLEYPELTDVGSLVTKVSATDLDEGFNGKIFYFIRSQ--SENFRINSSTGEIFVK--QQLRYQNSTGHNNANINRHSFIVTASDRGIKPLMSETTVIVNIVDSNDNPPTFESSSYFTPVTKSVKVGTNLIKVTAHDKKDFGVNSEIEYVISGGNSSSKFRLDKQTGWVTVASSLTSDINKV-YLLEITAKDKGNPVLSDKATLKIAVTEENHHTPEFSQSQVIAAVSESLTVGTAIRTLSARDKDKDKQMNG----LITYNISSGNDDGLFVVNEKTGVLSLAKPLDYEKKQKHELRISATDGGWIAKTSYVTVNIQVTDVNDNPPMFEPDEYFPVVQENVPSGTIVVKLNATDKDSSSNSVMAYVIQSSDSDLFIIDPNTGVITTQGFLDYEAKQVYHLTVKAFNVPDEERCSFANVNIQLKGANEYVPRFVSKQY-----YFEVSEAAPKGTMVGEVFASDRDLGDDGVVYYLIFGRSRRKGFGINKKTG-------QIYVTGPLDREKEEKISLKVLAKNAGSIRGADIDEVFVNITILDANDPP 3387 HSP 9 Score: 58.5362 bits (140), Expect = 1.074e-7 Identity = 143/672 (21.28%), Postives = 270/672 (40.18%), Query Frame = 1 Query: 793 FQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDED----INELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYF---IQLIDVNEAPQGLTL--YPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANER-PENLSLSNN-QIPENEPIGLLIAIINAQDND-KNSTLVYTL---DVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPK-LNVSKTF-DIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEI-KNIFQYDLTINQT-----LDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNE-PPTKLAIDGSREIIINITENIQGYQSIANFITTDPD---QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLK-WFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKS 2706 +I+ D+ N LS+ + I +EN + + S + E + ++ LSA D+D +N L ++ I + D + + ++ + + L+YE + + A D I +Y IQ+ DVN+ P Y V EN+PSG+++ K + D + +S + + +++F+I + LDYE Y+L ++ + E + + +++ ANE P +S ++ E P G ++ + A D D + +VY L K F I + ++ D E + + + G + ++ + F +I IL++N+ P E++ + + L V D D + SRF ++ KN F + Q LD E + + + D + T + + +E++N+ PT + G + EN + + + DPD YS+L+ + F ++ G L S+ D E + V+I+ DSG +S V + I D ND P+ + + + F G + + + ++ +CS+I P FSI + S NL + R D F D+ ++ + H+ + S Sbjct: 3040 LEITAKDKGNPVLSDKATLKIAVTEENHHTPEFSQSQVIAAVSESLTVGTAIRTLSARDKDKDKQMNGLITYNISSGNDDGLFVVNEKTGVLSLAKPLDYEKKQKHELRISA-TDGGWIAKTSYVTVNIQVTDVNDNPPMFEPDEYFPVVQENVPSGTIVVKLNATDKDSSSNSVMAYVIQSSDSDLFIIDPNTGVITTQGFLDYEAKQVYHLTVKAFNVPDEERCSFANVNIQLKGANEYVPRFVSKQYYFEVSEAAPKGTMVGEVFASDRDLGDDGVVYYLIFGRSRRKGFGINKKTGQIYVTGPLDREKEEKISLKVLAKNAGSIRGADIDEVFVNITILDANDPPVFT--------QELYDVQVSEGLSPGGLVTFVSAEDSDS------VPSWSRFTYSVTTDREKNAFTINPQTGQVSVAAELDRETTPVYNLTLLAIDSGSPAATGTATLIVTLEDINDNGPTLVTTTG------EVMENQRAGTPVMTLNSVDPDLAPNQGPFSYSLLSTGSAVTYFTLTSSGE---LSTSREIDREQISDFYLSVVIK--DSGVPQMSSTGTVHVKINDQNDNPSQP-RSVEIFVHYFGNMFPGGSLGIVKPQDPDIHDTFQCSLIPPAASLFSIPSGSCNLN---SNARSTDGTF-DVSVRSNDGVHSPVNS 3680 HSP 10 Score: 57.7658 bits (138), Expect = 1.949e-7 Identity = 117/540 (21.67%), Postives = 223/540 (41.30%), Query Frame = 1 Query: 1894 DDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQT-------------LDYEQNNYFEINIEINDM---KNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND-PPTVAGLNFTMIPSFVEKD------FIIGKVNVFDEDNLSTYNQIECSIIKP--LKWFSI-LNISQNLEIVTTATRFIDEKF--IDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFN-WTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDP--LDYETENNFLISFTLIDKNSNQSIN---LKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQ----IHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVND 3387 D I + + +VQ + K F+ D+T+N + LD E ++++ IE+ D K + +++ + ++++N+ P +D + ++ E+ S+ TD D+ N I+Y L+ F+ + +KE+ DYE + K+ + I A+D+G LS E I + D ND P V F F D ++ + V D D+ S I SI+ F + + NL ++ A+ E+ ++ + +NG +S+ S + + DIN+ P F + VD ++E+ S + + TD S Q + ++ N++ +NS ++T LD ET + +++ + D+ I+ L V I DVN+ ++++ E SP + + ATD D +FD + E+F + + +L T + +Y+ Y + D G P L ++ + + ++ND Sbjct: 149 DADIGSNGVDHTTYRIVQGNEQRK--FRLDITVNPSGEGAFLHLVTTGGLDRELAPFYQLLIEVEDKGEPKRY-GYLQVNVTIQDINDNPPAFDLD---QYQTSVYEDAAIGSSVLQITATDQDEGANSDIRY----FLDEGTPFQIDPKAGTVVIKEA--LDYE--VKKEYSLTIHAVDNGVPSLSGRTEATIKLLDVNDNDPVVKFRYFPTTSKFASVDENAQIGTVVALLTVSDSDSSSANGNISVSILGGNEQGHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGRPVSRSSFASLVIFVNDINDHPPIFQEAVYKVD-ISEDVPKGSYIKGVSATD--GDSGQNANLRYSLVSGNSLGWFAISENSGLVTSAALLDRETASVVVLNISAKDQGLQPKISYTKLIVNITDVNDQVPTFTQSSYHVSLVEHSPAGSELLSLSATDTDLGANGTVRFTFDAETPATVQELFR---LDTITGKLSTTTELDREDMGSYLLY----VRATDAGAPPLHSIAKVNVTLKDIND 664 HSP 11 Score: 56.225 bits (134), Expect = 4.783e-7 Identity = 220/1091 (20.16%), Postives = 441/1091 (40.42%), Query Frame = 1 Query: 88 ESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND-------PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVD-ANFNLFTKAPLDYETQARFEVIIECLDH---ENSSVINKHEISVTDINE-AP--DKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTD-------LKLNDSTSNKVLIEENSSNYSLGELSAIDEDIN-ELYSF-----QILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQI--LIFNKTYFIQLIDVNEAPQGL--TLYPSTVTENIPSGSVIGKFSILDS---NLNSTIEKCSLQLITFNEIFLISQFQLELKDN-----TRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDNDK----NSTLVYTLDV-NEKDFYIENNK---LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQII-----SDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD-QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDS-GGLSID-LEVPISIQDANDPPT-VAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSII--KPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKS----SIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQ---SINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPD 3153 + + E S+ PL++E+ + L I A+D P S I + +LD ND P + ++ + +LV S + Q S + LD + K +S F+++ A + T PLD E A++ + ++ D + S+ ++ I+V D+N+ AP KI+ T EN+ G + + D D T + VS +L + +I I L N E ++S D + ++S V I + ++++N L+ + T L+ + S+ + +DE N +++ F + +++ + EI K +L + S N + + F+V A I L+ T + ++D N+ P + Y + VT+++ G+ + K + D +NS IE +I+ S+F+L+ + + L + Y L I D G + + + +++ N S S + E+ +G I ++A+D DK N + Y + N+ ++ N K L D+E + +++ I+ D G T +I++ + N+NP + D+Y F +++ N T + + D D N + SD+ F++ + + +T LDYE + + ++ ++ + + + I ++ NE + S++ ++E + +D D +D + Y ++ + + F + ++Y+ D E +KVL + S G ID + V I+I DANDPP L + + ++ V+ D D++ ++++ S+ + F+I + + + R + ++ + ++G + + T + + +EDIN+ T V E N G ++ + + L ++ S++ S + + +D E ++F +S + D Q + + V+I D N+ PS+ +S E + F P + DPD Sbjct: 2598 DQLSGELSLKAPLDYENIEKYV-LWIEARDQSFPPYSAYEKIEITVLDVNDNNPVFEKEPFHAEILENLSPQRVLVVSALDQDSGPNGQLDYTIIDGNKENS-FSINRATGEIRTTRPLDREKTAQYSLKVKATDRGAPQKSTAVSV-VINVLDVNDNAPRFSKIFS--------ATVPENAPVGYTVTRVTTTDED--------TGANAVSRYTISDTSLPFSINPSTGDITISRPL--NREDTDHYIAKVSAHD-SGWTVSTDVTIFVTDINDNAPRFSKPSYYLEYPELTDVGSLVTKVSA-------TDLDEGFNGKIFYFIRSQSENFRINSSTGEIFVKQQLRYQNSTGHNNANINRHSFIVTASDRGIKPLMSETTVIVNIVDSNDNPPTFESSSYFTPVTKSVKVGTNLIKVTAHDKKDFGVNSEIE----YVISGGNSS--SKFRLDKQTGWVTVASSLTSDINKVYLLEITAKDKGNPVLSDKATLKIAVTEENHHTPEFSQSQVIAAVSESLTVGTAIRTLSARDKDKDKQMNGLITYNISSGNDDGLFVVNEKTGVLSLAKPLDYEKKQKHELRISATDGGWIAKTSYVTVNIQVTDVNDNPPMFEPDEY------FPVVQENVPSGTIV-VKLNATDKDSSSNSVMAYVIQSSDSDLFIIDPNTGV-------ITTQGFLDYEAKQVYHLTVKAFNVPDEERCSFANVNIQLKGANEYVPRFV---SKQYYFEVSEAAPKGTMVGEVFASDRDLGDDGVVYYLIFGRSRRKGFGINKKTGQIYVTGP--LDREKEEKISLKVLAKNAGSIRGADIDEVFVNITILDANDPPVFTQELYDVQVSEGLSPGGLVTFVSAEDSDSVPSWSRFTYSVTTDREKNAFTINPQTGQVSVAAELDRETTPVY-NLTLLAIDSG-SPAATGTATLIVTLEDINDNGPTL-----VTTTGEVMENQRAGTPVMTLNSVDPDLAPNQGPFSYSLLSTGSAVTYFTLTSSGELSTSREIDREQISDFYLSVVIKDSGVPQMSSTGTVHVKINDQNDNPSQPRSVEIFVHYFGNMFPGGSLGIVKPQDPD 3627
BLAST of Protocadherin Fat 4 vs. Ensembl Cavefish
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:103042072]) HSP 1 Score: 109.383 bits (272), Expect = 4.069e-23 Identity = 64/183 (34.97%), Postives = 94/183 (51.37%), Query Frame = 1 Query: 5176 ICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKN 5691 +CH + SN C+ A C +N LN C C GF+G G+ +++DEC N C +C++ V FQC CG +G CE+ +N CL C + C D + +C+C+ G+ G C ID+C +PC G+C D +N F C CQ FTG C+ D C + +N C++ N Sbjct: 265 LCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFIG-GACIQDMDECSIGANPC-EHFGKCVNTVGSFQCQCGRGYTGPRCEI-DINECLSMPCQNDATCLDRIGEFTCICMPGYTGTHCEIDIDECESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECASTPCQNGAKCIDRPN 444 HSP 2 Score: 98.9821 bits (245), Expect = 5.364e-20 Identity = 58/179 (32.40%), Postives = 89/179 (49.72%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 I I SN C + C+ +L + F C C GF G+ C+ +IDEC C + ++CID N ++C C GR CE ++ C C HG C D +C C+ G+ G C +++C +PC G C D +N +IC CQ +G CE ++ C + +G+C + N+ Sbjct: 385 IDIDECESNPCVNDGICR--DLVNAFTCTCQTGF--TGTMCQIDIDECASTPC-QNGAKCIDRPNGYECRCAEGFEGRLCES-NIDNCQPDPCHHGTCVDGIASYTCNCVPGYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINYDDCASNPCEYGMCKDGINR 557 HSP 3 Score: 96.6709 bits (239), Expect = 2.860e-19 Identity = 58/152 (38.16%), Postives = 74/152 (48.68%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTG 5616 C N + C N C+ D + C C PGF G + E +DEC N C + C+D N F CLC + C V+ C S CVHG CR+D C C GW G +C+ +DC+ +PC G C D LNGF C C+Q F G Sbjct: 534 CEINYDDCASNP-CEYGMCKDGINRYDCVCKPGFTGPQCNVE-LDECSSNPCR-NGGTCVDDENGFHCLCPAGFHEPYC-FSHVDECSSSPCVHGACREDPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAGTCIDQLNGFTCKCRQGFRG 681 HSP 4 Score: 91.2781 bits (225), Expect = 1.270e-17 Identity = 57/173 (32.95%), Postives = 86/173 (49.71%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C +N C C + FQC C G+ G CE +I+ECL C D++ C+D + +F C+C +G CE+ ++ C + CV+ GICRD +C C +G+ G C ID+C PC C D NG+ C C + F G CE + +C+ + G C++ Sbjct: 312 CSIGANPCEHFGKCVNTV--GSFQCQCGRGY--TGPRCEIDINECLSMPCQNDAT-CLDRIGEFTCICMPGYTGTHCEI-DIDECESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECASTPCQNGAKCIDRPNGYECRCAEGFEGRLCESNIDNCQPDPCHHGTCVD 478 HSP 5 Score: 88.9669 bits (219), Expect = 5.625e-17 Identity = 60/173 (34.68%), Postives = 80/173 (46.24%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC---KNCSENFGVCLN 5682 ++ C A C + N+ + C C PGF G +C +IDEC + CI+ F+C C S SGRTCEV C S C++ G C C CL G+ G +C ++DDC G C G C D +N + C C +TG +C D C N N G C N Sbjct: 43 TSPCANGARCTN--WNNHYNCSCPPGF--QGKNCRNDIDECRKPGKCLNGGICINTHGSFRCECVSGYSGRTCEV-PTQPCAPSQCLNGGTCHQTGDHTYECACLPGFGGTNCEVNVDDCPGHKCMNGGTCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFN 210 HSP 6 Score: 87.0409 bits (214), Expect = 2.197e-16 Identity = 55/171 (32.16%), Postives = 81/171 (47.37%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKN 5691 N C +A C +QC C PG+ G+ + + ++EC N C + C + + + C C SG CE +N CL + C+ G C D + C CL G+ G C +D+C PC G C D +N + C C+ FTG+ CE + C S N G C++ N Sbjct: 696 NPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNID-VNECASNPC-KNRGTCTNTLGGYVCSCRGGYSGPNCET-DINDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAIEVDECQSAPCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKIN 863 HSP 7 Score: 84.7297 bits (208), Expect = 1.015e-15 Identity = 52/149 (34.90%), Postives = 74/149 (49.66%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHF-SCKNCSENFGVC 5676 + C C PG+ G CE +++EC N C + +C+DLVN + C C SG CE+ + C + C +G+C+D C+C G+ G CN +D+C +PC G C D NGF C C F +C F H C + G C Sbjct: 483 YTCNCVPGY--TGYRCENQLNECHSNPC-QNGGKCVDLVNKYICQCQHGTSGTNCEI-NYDDCASNPCEYGMCKDGINRYDCVCKPGFTGPQCNVELDECSSNPCRNGGTCVDDENGFHCLCPAGFHEPYC-FSHVDECSSSPCVHGAC 626 HSP 8 Score: 83.1889 bits (204), Expect = 3.643e-15 Identity = 53/168 (31.55%), Postives = 83/168 (49.40%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCL-KSDCVH--GICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVC 5676 ++C TC + ++C C PGF G++CE +D+C + C+ + C+D VN + C C + +G+ C VN CL + + H G C + ++C+C++GW G DC+++IDDC C C D + F C C TG+ C D N VC Sbjct: 121 SQCLNGGTCHQTG-DHTYECACLPGF--GGTNCEVNVDDCPGHKCM-NGGTCVDGVNTYNCQCPPEWTGQYC-AEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFYCECPVGKTGLLCHLDDACVSNPCNEGAVC 283 HSP 9 Score: 82.0333 bits (201), Expect = 8.235e-15 Identity = 51/145 (35.17%), Postives = 74/145 (51.03%), Query Frame = 1 Query: 5239 DEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLC--GSDRSGRTC-EVLKVNLCLKSDCV-HGICRDDN-----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 D ++C C PG+VG + ++CL N C ++ CID +N F C C G G TC EVL C + C H +C C C GW+G CN +++C +PC RG C + L G++C+C+ ++G CE D C Sbjct: 631 DGYRCECEPGWVGKNCDLDR-NDCLPNPC-QNAGTCIDQLNGFTCKCRQGFRGGGPTCAEVL--TPCSPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNIDVNECASNPCKNRGTCTNTLGGYVCSCRGGYSGPNCETDINDC 771 HSP 10 Score: 81.6481 bits (200), Expect = 9.033e-15 Identity = 58/168 (34.52%), Postives = 84/168 (50.00%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN-CSENFGVC 5676 SN C TC +N L + C C G+ +G +CE +I++CL N C+ S C D +N F C C +G C + +V+ C + C +G C D +C C G+ G+ C + DC C G C D +NGF C C+ FTG C+++ C + N GVC Sbjct: 735 SNPCKNRGTC-TNTLGG-YVCSCRGGY--SGPNCETDINDCLPNPCMSGGS-CTDGINTFYCTCLPGFTGPRCAI-EVDECQSAPCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVC 896 HSP 11 Score: 80.8777 bits (198), Expect = 1.877e-14 Identity = 57/175 (32.57%), Postives = 78/175 (44.57%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK--NCSENFGVC 5676 C + N C N D F C C PGF G + E +DEC C + C D VN + C C +G CE ++ C +S C +G C D SC C G+ G C +++C PC GVC+D L F C+C + +TG C+ C+ N +N G C Sbjct: 764 CETDINDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAIE-VDECQSAPC-KNGGTCTDYVNSYTCTCKPGFTGLHCETNAMD-CTESSCFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQDGLESFRCSCPKGYTGSRCQVRVDWCRHSNPCQNGGRC 935 HSP 12 Score: 72.0182 bits (175), Expect = 9.060e-12 Identity = 48/164 (29.27%), Postives = 75/164 (45.73%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGN-----GSSCE--EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 +SN C C+ + + C C G+ G G SCE + L+ C C++ N C C +D +G CE +V+ C C++G CR +C C+ G+EG +C + I++C PC G C D + +IC+C G+ CE + C Sbjct: 925 HSNPCQNGGRCRPKDGS----CDCVGGWSGRYCDIPGVSCEMAAMQRGLYELC-HRGGHCVNTGNTHYCKCPNDYTGSYCES-QVDHCEDKPCLNGATCRGYVGGYTCDCMPGYEGQNCEREINECRSHPCQNGGTCIDLVGHYICSCPPGTMGVLCEINEDDC 1082 HSP 13 Score: 69.707 bits (169), Expect = 3.978e-11 Identity = 55/177 (31.07%), Postives = 80/177 (45.20%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS------CLCLSGWEGIDCNKSIDDC-IG-DPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLN 5682 C N CH TC N + C C G+ G+ S E ID+C C + + C D V F C C ++G C + + C+ + C G D N C C +G+ G C + +D+C IG +PC G C + + F C C + +TG CE D C + +N CL+ Sbjct: 195 CLMQPNACHNGGTC-FNTIGGH-TCVCVNGWTGDDCS-ENIDDCATAVCF-NGATCHDRVASFYCECPVGKTGLLCHL--DDACVSNPCNEGAVCDTNPLNGRAICTCPAGFIGGACIQDMDECSIGANPCEHFGKCVNTVGSFQCQCGRGYTGPRCEIDINECLSMPCQNDATCLD 365 HSP 14 Score: 58.9214 bits (141), Expect = 8.003e-8 Identity = 53/161 (32.92%), Postives = 69/161 (42.86%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCI------GDP-CNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 CHR C N N + C C + GS CE ++D C CL + + C V + C C G+ CE ++N C C +G C D C C G G+ C + DDC G P C G C D + G+ CNC +TG CE D C Sbjct: 973 CHRGGHC-VNTGNTHY-CKCPNDY--TGSYCESQVDHCEDKPCL-NGATCRGYVGGYTCDCMPGYEGQNCE-REINECRSHPCQNGGTCIDLVGHYICSCPPGTMGVLCEINEDDCATPTRPRGTPKCQNNGTCVDRVGGYRCNCPPGYTGDRCEGDINEC 1127 HSP 15 Score: 52.373 bits (124), Expect = 6.766e-6 Identity = 43/162 (26.54%), Postives = 65/162 (40.12%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELN-----DEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG----ICRDDNSCLCLSGWEGIDC-NKSIDDCIGDPCNGRGVCEDALN--GFICNCQQNFTGIFCE 5628 C + N+CH N +N L+ +++ C C PGF G G C F + +S C + C +G CE + C + C +G + C C G+ G C ++S C PC G+C + N F C C + + G CE Sbjct: 1120 CEGDINECHSNPCNAANSLDCIQLPNDYLCVCKPGFTGRG--------CQNRFGVCESQPCKN-----GGACSGGYTGTNCE--RSMSCRELSCYNGGSCTVTSRGARCSCQQGFAGPQCQHRSNQSCSSKPCRNNGICIEEANFPFFSCQCMEGWKGKRCE 1266
BLAST of Protocadherin Fat 4 vs. Ensembl Cavefish
Match: svep1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 [Source:NCBI gene;Acc:103042618]) HSP 1 Score: 101.293 bits (251), Expect = 1.082e-20 Identity = 61/159 (38.36%), Postives = 80/159 (50.31%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK 5649 +S C C+ FQC C PGFVG S CE E++EC + CL D C+D VN F C C +G CE L+++ C S C +G C+D SC C G+ G C +ID+C PC G C D +N F C C Q + G C+ D C+ Sbjct: 1238 DSTPCQNGGLCRDGM--GGFQCQCQPGFVG--SLCEAEVNECSSSPCLNDGV-CVDEVNRFTCSCTDGFTGPRCE-LEIDECESSPCQNGGECKDLEAGYSCSCSQGFTGDSCEINIDECYSAPCLNGGTCVDDINDFRCECVQGYRGKLCQVDEDECE 1390 HSP 2 Score: 83.5741 bits (205), Expect = 2.548e-15 Identity = 52/160 (32.50%), Postives = 73/160 (45.62%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSNELNDE---FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 S+C N+C + DE F C C GF G CE EIDEC + C + C DL + C C +G +CE+ ++ C + C++G C DD + C C+ G+ G C D+C +PC CED + + C C F G CE Sbjct: 1266 SLCEAEVNECSSSPCLNDGVCVDEVNRFTCSCTDGFTG--PRCELEIDECESSPC-QNGGECKDLEAGYSCSCSQGFTGDSCEI-NIDECYSAPCLNGGTCVDDINDFRCECVQGYRGKLCQVDEDECEPNPCVNGATCEDGVGSYTCRCPPGFNGTRCE 1421 HSP 3 Score: 68.5514 bits (166), Expect = 1.035e-10 Identity = 42/133 (31.58%), Postives = 64/133 (48.12%), Query Frame = 1 Query: 5305 ECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLK 5688 EC N C + C ++ + C C +G CE ++ C + C +G +CRD C C G+ G C +++C PC GVC D +N F C+C FTG CE + C++ +N G C +L+ Sbjct: 1198 ECFLNPCQNQGT-CEEVGVGYVCTCLPGFTGAKCES-DIDECDSTPCQNGGLCRDGMGGFQCQCQPGFVGSLCEAEVNECSSSPCLNDGVCVDEVNRFTCSCTDGFTGPRCELEIDECESSPCQNGGECKDLE 1328 HSP 4 Score: 63.929 bits (154), Expect = 2.217e-9 Identity = 29/74 (39.19%), Postives = 38/74 (51.35%), Query Frame = 1 Query: 5476 CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKNK 5694 C CL G+ G C ID+C PC G+C D + GF C CQ F G CE + C + N GVC++ N+ Sbjct: 1219 CTCLPGFTGAKCESDIDECDSTPCQNGGLCRDGMGGFQCQCQPGFVGSLCEAEVNECSSSPCLNDGVCVDEVNR 1292
BLAST of Protocadherin Fat 4 vs. Ensembl Cavefish
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:103042072]) HSP 1 Score: 98.9821 bits (245), Expect = 4.845e-20 Identity = 71/220 (32.27%), Postives = 103/220 (46.82%), Query Frame = 1 Query: 5065 ADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNLKN 5691 A + F T R P+ K L +CH + SN C+ A C +N LN C C GF+G G+ +++DEC N C +C++ V FQC CG +G CE+ +N CL C + C D + +C+C+ G+ G C ID+C +PC G+C D +N F C CQ FTG C+ D C + +N C++ N Sbjct: 295 ATAVCFNGATCHDRVASFYCECPVGKTGL--------LCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFIG-GACIQDMDECSIGANPCE-HFGKCVNTVGSFQCQCGRGYTGPRCEI-DINECLSMPCQNDATCLDRIGEFTCICMPGYTGTHCEIDIDECESNPCVNDGICRDLVNAFTCTCQTGFTGTMCQIDIDECASTPCQNGAKCIDRPN 503 HSP 2 Score: 89.3521 bits (220), Expect = 4.661e-17 Identity = 54/136 (39.71%), Postives = 70/136 (51.47%), Query Frame = 1 Query: 5239 DEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 + + C C PGF G C E+DEC N C + C+D N F CLC + C V+ C S CVHG CR+D C C GW G +C+ +DC+ +PC G C D LNGF C C+Q F G C+ + Sbjct: 615 NRYDCVCKPGFTG--PQCNVELDECSSNPCR-NGGTCVDDENGFHCLCPAGFHEPYC-FSHVDECSSSPCVHGACREDPDGYRCECEPGWVGKNCDLDRNDCLPNPCQNAGTCIDQLNGFTCKCRQGFRGNQCQVN 746 HSP 3 Score: 87.0409 bits (214), Expect = 2.117e-16 Identity = 56/172 (32.56%), Postives = 87/172 (50.58%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 SN C + C+ +L + F C C GF G + C+ +IDEC C + ++CID N ++C C GR CE ++ C C HG C D +C C+ G+ G C +++C +PC G C D +N +IC CQ +G CE ++ C + +G+C + N+ Sbjct: 451 SNPCVNDGICR--DLVNAFTCTCQTGFTG--TMCQIDIDECASTPCQ-NGAKCIDRPNGYECRCAEGFEGRLCES-NIDNCQPDPCHHGTCVDGIASYTCNCVPGYTGYRCENQLNECHSNPCQNGGKCVDLVNKYICQCQHGTSGTNCEINYDDCASNPCEYGMCKDGINR 616 HSP 4 Score: 82.4185 bits (202), Expect = 6.109e-15 Identity = 58/155 (37.42%), Postives = 80/155 (51.61%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTC-EVLKVNLCLKSDCV-HGICRDDN-----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 N C TC ++LN F C C GF GN C+ I+EC + CL + C+D V F CLC + SG TC EVL C + C H +C C C GW+G CN +++C +PC RG C + L G++C+C+ ++G CE D Sbjct: 715 NPCQNAGTCI-DQLNG-FTCKCRQGFRGN--QCQVNINECASSPCL-NQGTCVDGVASFTCLCEAPYSGPTCAEVLTP--CSPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCNIDVNECASNPCKNRGTCTNTLGGYVCSCRGGYSGPNCETD 862 HSP 5 Score: 81.2629 bits (199), Expect = 1.138e-14 Identity = 59/172 (34.30%), Postives = 78/172 (45.35%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC---KNCSENFGVCLN 5682 ++ C A C + N+ + C C PGF G +IDEC + CI+ F+C C S SGRTCEV C S C++ G C C CL G+ G +C ++DDC G C G C D +N + C C +TG +C D C N N G C N Sbjct: 102 TSPCANGARCTN--WNNHYNCSCPPGFQGKNCR-NDIDECRKPGKCLNGGICINTHGSFRCECVSGYSGRTCEV-PTQPCAPSQCLNGGTCHQTGDHTYECACLPGFGGTNCEVNVDDCPGHKCMNGGTCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFN 269 HSP 6 Score: 76.6406 bits (187), Expect = 3.453e-13 Identity = 54/173 (31.21%), Postives = 80/173 (46.24%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDN----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSE-NFGVCLNLKN 5691 + N C +A C +QC C PG+ G+ + +++EC N C + C + + + C C SG CE +N CL + C+ G D C CL G+ G C +D+C PC G C D +N + C C+ FTG+ CE + C S N G C++ N Sbjct: 789 SPNPCSNHAVCTHTPDYFGYQCNCQPGWQGHLCN-IDVNECASNPCK-NRGTCTNTLGGYVCSCRGGYSGPNCET-DINDCLPNPCMSGGSCTDGINTFYCTCLPGFTGPRCAIEVDECQSAPCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKIN 958 HSP 7 Score: 73.559 bits (179), Expect = 2.707e-12 Identity = 50/157 (31.85%), Postives = 79/157 (50.32%), Query Frame = 1 Query: 5185 FNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCL-KSDCVH--GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 N CH+ + ++C C PGF G++CE +D+C + C+ + C+D VN + C C + +G+ C VN CL + + H G C + ++C+C++GW G DC+++IDDC C C D + F C C TG+ C D Sbjct: 183 LNGGTCHQTG-------DHTYECACLPGF--GGTNCEVNVDDCPGHKCM-NGGTCVDGVNTYNCQCPPEWTGQYC-AEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFYCECPVGKTGLLCHLD 328 HSP 8 Score: 71.633 bits (174), Expect = 1.101e-11 Identity = 53/153 (34.64%), Postives = 78/153 (50.98%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 SN C TC +N L + C C G+ +G +CE +I++CL N C+ S C D +N F C C +G C ++V+ C + C +G C D +C C G+ G+ C + DC C G C D +NGF C C+ FTG C+++ Sbjct: 830 SNPCKNRGTC-TNTLGG-YVCSCRGGY--SGPNCETDINDCLPNPCMSGGS-CTDGINTFYCTCLPGFTGPRC-AIEVDECQSAPCKNGGTCTDYVNSYTCTCKPGFTGLHCETNAMDCTESSCFNGGTCVDKINGFSCTCRVGFTGEHCQYE 976 HSP 9 Score: 70.0922 bits (170), Expect = 3.176e-11 Identity = 53/151 (35.10%), Postives = 72/151 (47.68%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK--NCSENFGVC 5676 F C C PGF G C E+DEC C + C D VN + C C +G CE ++ C +S C +G C D SC C G+ G C +++C PC GVC+D L F C+C + +TG C+ C+ N +N G C Sbjct: 884 FYCTCLPGFTG--PRCAIEVDECQSAPCK-NGGTCTDYVNSYTCTCKPGFTGLHCETNAMD-CTESSCFNGGTCVDKINGFSCTCRVGFTGEHCQYEVNECDSQPCLNGGVCQDGLESFRCSCPKGYTGSRCQVRVDWCRHSNPCQNGGRC 1030 HSP 10 Score: 61.2326 bits (147), Expect = 1.554e-8 Identity = 49/179 (27.37%), Postives = 75/179 (41.90%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGN-----GSSCE--------EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGV 5673 +SN C C+ + C C G+ G G SCE + DE C++ N C C +D +G CE +V+ C C++G CR +C C+ G+EG +C + I++C PC G C D + +IC+C G+ CE + C + G Sbjct: 1020 HSNPCQNGGRCRPKD----GSCDCVGGWSGRYCDIPGVSCEMAAMQRGLQTDELCHR-----GGHCVNTGNTHYCKCPNDYTGSYCES-QVDHCEDKPCLNGATCRGYVGGYTCDCMPGYEGQNCEREINECRSHPCQNGGTCIDLVGHYICSCPPGTMGVLCEINEDDCATPTRPRGT 1188 HSP 11 Score: 58.9214 bits (141), Expect = 7.172e-8 Identity = 51/163 (31.29%), Postives = 75/163 (46.01%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS------CLCLSGWEGIDCNKSIDDC-IG-DPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 ++ C N CH TC N + C C G+ G+ S E ID+C C + + C D V F C C ++G C + + C+ + C G D N C C +G+ G C + +D+C IG +PC G C + + F C C + +TG CE D Sbjct: 251 VNECLMQPNACHNGGTC-FNTIGGH-TCVCVNGWTGDDCS-ENIDDCATAVCF-NGATCHDRVASFYCECPVGKTGLLCHL--DDACVSNPCNEGAVCDTNPLNGRAICTCPAGFIGGACIQDMDECSIGANPCEHFGKCVNTVGSFQCQCGRGYTGPRCEID 407 HSP 12 Score: 55.0694 bits (131), Expect = 9.949e-7 Identity = 44/153 (28.76%), Postives = 73/153 (47.71%), Query Frame = 1 Query: 5218 CKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDS---SRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI-CRDDN---SCLCLSGWEGIDCNKSIDDC--IGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK 5649 C++ + + +C C PG++ G C+ +D C + CL + S+ + V F C+C G+ C + ++ C S C +G C + N +C C G++G +C ID+C G NG G+C + F C C ++G CE C Sbjct: 31 CENGGMCLDSRCMCRPGYI--GPLCQHLDPCHRSPCLNGAACKSQVANGVPQFTCVCQRGFRGQNCSL--IDACATSPCANGARCTNWNNHYNCSCPPGFQGKNCRNDIDECRKPGKCLNG-GICINTHGSFRCECVSGYSGRTCEVPTQPCA 178 HSP 13 Score: 52.7582 bits (125), Expect = 5.251e-6 Identity = 52/157 (33.12%), Postives = 68/157 (43.31%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCI------GDP-CNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 CHR C N N + C C + G S CE ++D C CL + + C V + C C G+ CE ++N C C +G C D C C G G+ C + DDC G P C G C D + G+ CNC +TG CE D Sbjct: 1070 CHRGGHC-VNTGNTHY-CKCPNDYTG--SYCESQVDHCEDKPCL-NGATCRGYVGGYTCDCMPGYEGQNCE-REINECRSHPCQNGGTCIDLVGHYICSCPPGTMGVLCEINEDDCATPTRPRGTPKCQNNGTCVDRVGGYRCNCPPGYTGDRCEGD 1220
BLAST of Protocadherin Fat 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 83.5741 bits (205), Expect = 4.822e-16 Identity = 234/1178 (19.86%), Postives = 451/1178 (38.29%), Query Frame = 1 Query: 109 SISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWK--VEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINE-APDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN---SLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDED--INELYSFQILILHTDSVEIKHKNEL-W--IKESAELNYESSYVNYFVVGA------YKDQILIFNKTYF---IQLIDVNEAPQGLTL--YPSTVTENIPSGSVIGKFSILDSNL--NSTIE-----KCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPENLSLSN-NQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTV-----FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFE-FSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND-PPTVAGLNFTMIPSFVEK---DFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIE--------------IQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDN------------SFMLTDPLDYETENNFLISFTLIDKNSN---QSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITY-----FWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTA 3399 + + PL+ E+ + +L + A+D P+ ++V + DAND P + ++ V E+ VG+ + DL + + PF+ + T+ PLD+E + ++ + + D N + + I + D+N+ P +V + +E++ GT ++ D D VS + + + +R+ ++ +R+ + +++ +N + S +++ D N + S L E + + +++A+D D +N + I+ N+L W + ES L V+ V + +DQ Y + L+DVN+ P T Y +T EN G + S DS+L N T+ Q + E+F + ++ LD E+ Y L ++ D G + + ++ + + D N+ P + I ENEP G + + A D D+ N T+ Y L + + N ++G V D E R YQ+ +T D G + I + ++ + P +D Y F + EN +++ D + + I+S + R + IF T N +D E+ ++++ + N + + V +VN + S E+ I E + D +N +KY I N EKF F +G +LY++ ++ + ++ + + A+D+G LS + V +++ D ND P ++ F E+ ++G V D D S + S KP N E+ + R + D E + + G K + + ++D+N+ P F+ + V+E+++N++ QLL +++ S + V+ ++ INE N L LD E ++ + + D ++ S + VQ+LD N+ P ++ E + + T A+D D S D++ IV G H+ I D ++ V ++ + + + + + D G+P S + + + + ND P A Sbjct: 89 ATTGPLDREANPS-YALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAAL-------RDLLHRGRGPLAV--PFDPKTGM-VSTRQPLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADS----PTANGELSVSIVGGNERGHFVLHAPGVPGLRV-LKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIV----------SGNDLGWFSVDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQ---YREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVN--AVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYS-----FVVFENVAPGTLVGSVSASTLDLNANVTYLIVSGDQRGSFSIEWSGGRIF----TAN-AIDREEQAFYQLRVVANS-GGVAGEASVSVLVHDVNNH-APVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEG-NGGEKFGIFPDG--QLYVR----YELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVF--HFCEEQEVGSLVGAVQATDADAGSN-GGVTYSFEKP---------QVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLT--QLL----------RVTASDVDEGVNGALRYAINEGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTGP--SGDVRYAIVAGN--THATFAI-------DRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPA 1181 HSP 2 Score: 60.4622 bits (145), Expect = 5.530e-9 Identity = 136/652 (20.86%), Postives = 254/652 (38.96%), Query Frame = 1 Query: 415 PLDYETQARFEVIIECL------------DHENSSVI-------NKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRN-DYLEFYT--NSTDVXXXXXXXXXXXXXYTKCLTEIRIQFEL---GFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPT-DLKLNDSTSNKVLIEENSSNYSLGELS---AIDEDINELYSFQILILH--TDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNE-AP--QGLTLYPSTVTENIPSGSVIGKFSILDSN--LNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQE---NIVTDFEIILEISDANE-RPENLSLSNNQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYIENNKL--------LSGTV-----FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEIND----MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQG 2178 PLD + F++ C+ D+ S I N+ EISV D+N+ P V EM L EN+ G I + D D+ + L Y+ + ++ + + + E R + L + ++ ++V D N+NS +V E+ D K + VL + S GE++ A ED + ++ LH T ++ + L+ ES A L ++ ++D N+ AP Q +L + V E+ P G+ + + S D + +N+ +E + + QL + LD E+ YNL +RV+D + + + + L ++D N+ P S + PE+ P+G ++A + A D D +NS + Y L + ++ ++G V D E R Y +T+ D G P L + T + + ++N+N + +Y I E+ ++ ++P D+ N ++ R+ + + F+ D L + + LD E+ +E+ + D ++ TA +++ + N P +L+ ++ EN QG Sbjct: 1456 PLDAPWRVSFDLTARCMFIVFSSLLSSLRDNGAGSFIRPPMSSFNQVEISVEDVNDNPPVFAV----PEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASRRLDREERASYLLTVRASDGTHATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSG-PFGEVTYALAPSEDSD--WADGAFGLHPVTGALNVTRP----------LDRESRACYVLRARATDGGGLAATARLYVNVLDANDNAPSVQNDSLA-AEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGNDGQLSVA--RALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAA-----IAEDEPPGTEVLRLSAWDP--DEGANGEL-----RYDIASGDPTGD-FRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLS-----PYTVHARENTQG 2069
BLAST of Protocadherin Fat 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004043.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004043.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 80.1073 bits (196), Expect = 5.844e-15 Identity = 46/144 (31.94%), Postives = 70/144 (48.61%), Query Frame = 1 Query: 5224 SNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHF 5640 S+E+ + C C G+ G + CE ++DECL C S C +L F C C SG CE V+ CL+ C +G +C + +C C +G+ G C+ ++D+C PC G C + G+ C C +G CE + Sbjct: 1508 SHEVLEPAVCTCTAGYAG--TWCEADMDECLSTPCRHGGS-CQNLPGGFACRCLPGFSGTACET-DVDECLEGPCQNGGLCHNTQGGFACDCSAGFSGKICDVTVDNCASSPCYNNGSCVNTATGYSCRCPFGMSGARCELTSY 1647 HSP 2 Score: 73.559 bits (179), Expect = 5.370e-13 Identity = 36/110 (32.73%), Postives = 56/110 (50.91%), Query Frame = 1 Query: 5371 CLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE--FDHFSCKNCSENFGVCLN 5682 C C + +G CE ++ CL + C HG C++ +C CL G+ G C +D+C+ PC G+C + GF C+C F+G C+ D+ + C N G C+N Sbjct: 1517 CTCTAGYAGTWCEA-DMDECLSTPCRHGGSCQNLPGGFACRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQGGFACDCSAGFSGKICDVTVDNCASSPCYNN-GSCVN 1624 HSP 3 Score: 64.6994 bits (156), Expect = 2.977e-10 Identity = 54/208 (25.96%), Postives = 99/208 (47.60%), Query Frame = 1 Query: 1210 TVTENIPSGSVIGKFSILD--SNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYIENNK---LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQY 1806 ++ EN P+GS + + + D + +N I S+ + +F IS+ ++ LDYE YNL + D G + + + ++D N+ P L+ S+ IPEN P G + +++A D D N+ +Y+LD E D ++ N K L + D+E + Y++T+ F+ D + ++I NE ++ +Y Sbjct: 763 SLPENHPAGSSLARVTATDTDAGVNGAIVY-SIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSLDDGEADLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREY 969 HSP 4 Score: 62.003 bits (149), Expect = 1.922e-9 Identity = 148/736 (20.11%), Postives = 297/736 (40.35%), Query Frame = 1 Query: 145 NNISLEILAKDLDVPKNS--KLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVK-----SDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELY-FQISVTDRNNNSLSEI--VKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDI--NELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGA--YKDQILIFNKTYFIQLIDVNEA-PQGLTL-YPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLI---TFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIIL--EISDANERPE-NLSLSNNQIPENEPIGLLIAIINAQDNDKN------STLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD----LTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFI----TTDPDQND 2226 N S + A D P S I++ + +AN P + + V + G+ + +S VD D D + + + + F+VDA L +A L + + F V +E D + ++ ISVT+ N+ + + + L+ EN +G+ + + D D N V S + + ++ ++ + EL + E+ LY + D + +E V I + +V++NP LN S V+ E S ++ + A+D D N + + + D + K + + L+YE+ V A Y D +Q+ VNE P+ + Y V+E+ P G+ +G S+ ++ ++ I+ ++ + ++ F +++ E+ +++LD E+ + L + + G E+++ I+DAN+ P + +L + ++ E +G + ++A D D S L+ + + + F I ++ + D E+ P Y +T+ D G+P + + + + N+N ++ T + EN MT + +PD L+ + F L + +D EQ F + + I D + T+ + + + V + N+ P++ +R++ +++ N G FI DPD +D Sbjct: 615 NKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNASRRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRF----AHPPLELSLPENHPAGSSLARVTATDTDAG------VNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEK---LYNLSVCAADGGWQAKTECSGVSISVTDVNDNPP--MLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSLDDGEADLFVLNQKTGVLTTQ-GFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVG--SVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDANDPPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAG-RAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLL-------TSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQ-----LLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNPSE-----ARDVRVHV--NYFGSPFPGGFIGDVRPRDPDISD 1312 HSP 5 Score: 61.6178 bits (148), Expect = 2.292e-9 Identity = 53/244 (21.72%), Postives = 102/244 (41.80%), Query Frame = 1 Query: 1372 LDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDND-KNSTLVYTLDVNEKD------FYIENNKLL-SGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTF-ATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQN--NYFEINIEINDMKNFTA 2070 LD E P YNL + D G+ +++ + D N+ L S+ ++ EN+P G+ + + A D D + YT + D F + ++ LL + D E +P + + + + D G P L + T + +L+ N+NP + + V + + F + +PD D+ NC + S N+F + + + ++ FE+++ +D K+ A Sbjct: 1134 LDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLLTSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNP----SEARDVRVHVNYF--GSPFPGGFIGDVRPRDPDISDRFNCDLTSGP-----------FNVFSFQPNTCRLISQPRSAEGRFELSVRGSDGKHSPA 1360 HSP 6 Score: 50.8322 bits (120), Expect = 4.512e-6 Identity = 121/617 (19.61%), Postives = 239/617 (38.74%), Query Frame = 1 Query: 1396 YNLGIRVTDYGQENIVTDFEIILEISDANE-------RPENLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEP-DFDDKINCQII-----SDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQN-DVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDS-GGLSID-LEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIG----KVNVFDEDNLSTYNQIECSIIK--PLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSS-IIVLVSNNIKIQ----INEDNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIA 3129 +++ + D G+ + + I+ +++ N+ P LSL PEN P G +A + A D D N +VY++ + + ++ SG V D+E Y +++ D G I + + N+NP ++ N ++ + ++ N T T+ V + D D N + + F++ +K+ + LT LDYE +E+ + + + + ++ + + VNE + RE ++E+ + + TD D D + +L + ++ F + ++ + S D E ++V+ + S G +D + V ++I DANDPP + + V + +G V+ D D+ + I + FSI N L +V + ++ + + G TT +A+ED+N+ F + VTEN G +L + + L +K L+ ++ + ++ P+D E + F + + D S ++ L + +LD N+ PSE + ++ F P I Sbjct: 721 FSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSL-----PENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRA-SGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPML------NASDYYPVIPENAPSGT--TVLVMDAVDADSPSNAVTMYSLDDGEADLFVLNQKTGV-------LTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFV---QREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIV--SSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDANDPPV---FSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSI-NAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTV-VVVALEDVNDN-GPFLLTSSAK-VTENQ---PAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNPSEARDVRVHVNYFGSPFPGGFIG 1301
BLAST of Protocadherin Fat 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004042.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 80.1073 bits (196), Expect = 5.851e-15 Identity = 46/144 (31.94%), Postives = 70/144 (48.61%), Query Frame = 1 Query: 5224 SNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHF 5640 S+E+ + C C G+ G + CE ++DECL C S C +L F C C SG CE V+ CL+ C +G +C + +C C +G+ G C+ ++D+C PC G C + G+ C C +G CE + Sbjct: 1508 SHEVLEPAVCTCTAGYAG--TWCEADMDECLSTPCRHGGS-CQNLPGGFACRCLPGFSGTACET-DVDECLEGPCQNGGLCHNTQGGFACDCSAGFSGKICDVTVDNCASSPCYNNGSCVNTATGYSCRCPFGMSGARCELTSY 1647 HSP 2 Score: 73.559 bits (179), Expect = 5.375e-13 Identity = 36/110 (32.73%), Postives = 56/110 (50.91%), Query Frame = 1 Query: 5371 CLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE--FDHFSCKNCSENFGVCLN 5682 C C + +G CE ++ CL + C HG C++ +C CL G+ G C +D+C+ PC G+C + GF C+C F+G C+ D+ + C N G C+N Sbjct: 1517 CTCTAGYAGTWCEA-DMDECLSTPCRHGGSCQNLPGGFACRCLPGFSGTACETDVDECLEGPCQNGGLCHNTQGGFACDCSAGFSGKICDVTVDNCASSPCYNN-GSCVN 1624 HSP 3 Score: 64.6994 bits (156), Expect = 2.716e-10 Identity = 54/208 (25.96%), Postives = 99/208 (47.60%), Query Frame = 1 Query: 1210 TVTENIPSGSVIGKFSILD--SNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDND--KNSTLVYTLDVNEKDFYIENNK---LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQY 1806 ++ EN P+GS + + + D + +N I S+ + +F IS+ ++ LDYE YNL + D G + + + ++D N+ P L+ S+ IPEN P G + +++A D D N+ +Y+LD E D ++ N K L + D+E + Y++T+ F+ D + ++I NE ++ +Y Sbjct: 763 SLPENHPAGSSLARVTATDTDAGVNGAIVY-SIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSLDDGEADLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREY 969 HSP 4 Score: 62.3882 bits (150), Expect = 1.307e-9 Identity = 148/736 (20.11%), Postives = 297/736 (40.35%), Query Frame = 1 Query: 145 NNISLEILAKDLDVPKNS--KLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVK-----SDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELY-FQISVTDRNNNSLSEI--VKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDI--NELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGA--YKDQILIFNKTYFIQLIDVNEA-PQGLTL-YPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLI---TFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIIL--EISDANERPE-NLSLSNNQIPENEPIGLLIAIINAQDNDKN------STLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD----LTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFI----TTDPDQND 2226 N S + A D P S I++ + +AN P + + V + G+ + +S VD D D + + + + F+VDA L +A L + + F V +E D + ++ ISVT+ N+ + + + L+ EN +G+ + + D D N V S + + ++ ++ + EL + E+ LY + D + +E V I + +V++NP LN S V+ E S ++ + A+D D N + + + D + K + + L+YE+ V A Y D +Q+ VNE P+ + Y V+E+ P G+ +G S+ ++ ++ I+ ++ + ++ F +++ E+ +++LD E+ + L + + G E+++ I+DAN+ P + +L + ++ E +G + ++A D D S L+ + + + F I ++ + D E+ P Y +T+ D G+P + + + + N+N ++ T + EN MT + +PD L+ + F L + +D EQ F + + I D + T+ + + + V + N+ P++ +R++ +++ N G FI DPD +D Sbjct: 615 NKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNASRRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRF----AHPPLELSLPENHPAGSSLARVTATDTDAG------VNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEK---LYNLSVCAADGGWQAKTECSGVSISVTDVNDNPP--MLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSLDDGEADLFVLNQKTGVLTTQ-GFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVG--SVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDANDPPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAG-RAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLL-------TSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQ-----LLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNPSE-----ARDVRVHV--NYFGSPFPGGFIGDVRPRDPDISD 1312 HSP 5 Score: 61.6178 bits (148), Expect = 2.163e-9 Identity = 53/244 (21.72%), Postives = 102/244 (41.80%), Query Frame = 1 Query: 1372 LDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDND-KNSTLVYTLDVNEKD------FYIENNKLL-SGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTF-ATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQN--NYFEINIEINDMKNFTA 2070 LD E P YNL + D G+ +++ + D N+ L S+ ++ EN+P G+ + + A D D + YT + D F + ++ LL + D E +P + + + + D G P L + T + +L+ N+NP + + V + + F + +PD D+ NC + S N+F + + + ++ FE+++ +D K+ A Sbjct: 1134 LDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLLTSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNP----SEARDVRVHVNYF--GSPFPGGFIGDVRPRDPDISDRFNCDLTSGP-----------FNVFSFQPNTCRLISQPRSAEGRFELSVRGSDGKHSPA 1360 HSP 6 Score: 51.2174 bits (121), Expect = 3.509e-6 Identity = 118/617 (19.12%), Postives = 241/617 (39.06%), Query Frame = 1 Query: 1396 YNLGIRVTDYGQENIVTDFEIILEISDANE-------RPENLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEP-DFDDKINCQII-----SDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQN-DVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDS-GGLSID-LEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIG----KVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDE--KFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSS-IIVLVSNNIKIQ----INEDNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIA 3129 +++ + D G+ + + I+ +++ N+ P LSL PEN P G +A + A D D N +VY++ + + ++ SG V D+E Y +++ D G I + + N+NP ++ N ++ + ++ N T T+ V + D D N + + F++ +K+ + LT LDYE +E+ + + + + ++ + + VNE + RE ++E+ + + TD D D + +L + ++ F + ++ + S D E ++V+ + S G +D + V ++I DANDPP + + V + +G V+ D D+ + +I+ +I+ + ++ A+ E ++ + + G TT +A+ED+N+ F + VTEN G +L + + L +K L+ ++ + ++ P+D E + F + + D S ++ L + +LD N+ PSE + ++ F P I Sbjct: 721 FSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSL-----PENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRA-SGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPML------NASDYYPVIPENAPSGT--TVLVMDAVDADSPSNAVTMYSLDDGEADLFVLNQKTGV-------LTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFV---QREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIV--SSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDANDPPV---FSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFS-FLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTV-VVVALEDVNDN-GPFLLTSSAK-VTENQ---PAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQNDNPSEARDVRVHVNYFGSPFPGGFIG 1301
BLAST of Protocadherin Fat 4 vs. Ensembl Sea Lamprey
Match: JAG1 (jagged canonical Notch ligand 1 [Source:HGNC Symbol;Acc:HGNC:6188]) HSP 1 Score: 75.8702 bits (185), Expect = 9.117e-14 Identity = 58/196 (29.59%), Postives = 85/196 (43.37%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH--------------------------------------GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKNKNQYC 5706 ++C C PG+ G + E+IDEC + C G+ C++LVN F+C C +G TC ++ + C + CVH G C+D D SC C G+ G C +++C PC G C DA++ + C C F G CE D C N +N C+NL N + +C Sbjct: 223 YKCLCAPGWTGANCT-EDIDECASSPC-GNGGTCLNLVNGFRCTCPPQWTGHTC-LVDTDECDDNPCVHARSCKNLFGGYYCGCLPGWTGQNCDIDVNDCEGKCLNGGTCKDLVNDYSCECKPGYTGRRCETEVNECASHPCLNGGQCRDAIDSYYCVCMDGFAGDSCELDVDLCVPNPCQNGARCVNLPNGDYFC 415 HSP 2 Score: 72.0182 bits (175), Expect = 1.486e-12 Identity = 49/148 (33.11%), Postives = 71/148 (47.97%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG----ICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTG 5616 N N C TC ++L ++F C C G+ G +C +I C C + C D+ + F+C C + G TC + + C+ + C +G I D C+C SGWEG +C + I+DC PC G C D N + C C F G Sbjct: 539 NHNPCLNGGTC--HDLVNDFSCECKNGW--KGKTCHSKISHCDEATC-NNGGECFDVGDTFRCSCPTGWEGPTCNIAQSIACMPNPCQNGATCVISGDSYKCICQSGWEGANCTQDINDCSSHPCYNGGTCVDGTNWYRCECAAGFAG 681 HSP 3 Score: 64.6994 bits (156), Expect = 2.038e-10 Identity = 54/160 (33.75%), Postives = 69/160 (43.12%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCE-----VLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC 5625 + H S C N C S + F C CN GF GS C E +++C C + C+D +N FQC+C G CE N CL G C D D SC C +GW+G C+ I C CN G C D + F C+C + G C Sbjct: 456 GVAHVTSTVCGPNGRCLS-QAGGNFTCMCNSGF--RGSFCHENVNDCAEGACH-NGGTCLDGINSFQCMCPDGWDGEFCENDVDDCSNHNPCLNG----GTCHDLVNDFSCECKNGWKGKTCHSKISHCDEATCNNGGECFDVGDTFRCSCPTGWEGPTC 607 HSP 4 Score: 61.6178 bits (148), Expect = 1.850e-9 Identity = 59/167 (35.33%), Postives = 81/167 (48.50%), Query Frame = 1 Query: 5173 SICHFNSN-----KCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECL-FNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI----CRDDNSCLCLSGWEGIDCN--KSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 S CH N N CH TC + FQC C G+ +G CE ++D+C N CL + C DLVNDF C C + G+TC K++ C ++ C +G D C C +GWEG CN +SI C+ +PC C + + + C CQ + G C D Sbjct: 490 SFCHENVNDCAEGACHNGGTCLDGI--NSFQCMCPDGW--DGEFCENDVDDCSNHNPCL-NGGTCHDLVNDFSCECKNGWKGKTCHS-KISHCDEATCNNGGECFDVGDTFRCSCPTGWEGPTCNIAQSIA-CMPNPCQNGATCVISGDSYKCICQSGWEGANCTQD 649 HSP 5 Score: 58.9214 bits (141), Expect = 1.303e-8 Identity = 57/187 (30.48%), Postives = 85/187 (45.45%), Query Frame = 1 Query: 5239 DEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVN-DFQCLCGSDRSGRTCEVLKVNLCLKSDC----------------------VHGICRDDN----------SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSE--NFGVCLNLKN 5691 D + C C GF G+ SCE ++D C+ N C + +RC++L N D+ C C + G C +LK + CL S C +C + +C+C SG+ G C+++++DC C+ G C D +N F C C + G FCE D C N + N G C +L N Sbjct: 372 DSYYCVCMDGFAGD--SCELDVDLCVPNPCQ-NGARCVNLPNGDYFCHCSENFEGTNCTLLK-DHCLTSPCQVIDSCTVAVPSNTSESGVAHVTSTVCGPNGRCLSQAGGNFTCMCNSGFRGSFCHENVNDCAEGACHNGGTCLDGINSFQCMCPDGWDGEFCENDVDDCSNHNPCLNGGTCHDLVN 554
BLAST of Protocadherin Fat 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009101.1 (pep scaffold:Pmarinus_7.0:GL486879:2800:7708:-1 gene:ENSPMAG00000008237.1 transcript:ENSPMAT00000009101.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 72.0182 bits (175), Expect = 2.317e-13 Identity = 52/149 (34.90%), Postives = 72/149 (48.32%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDE-CLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVC--EDALNGFICNCQQNFTGIFC 5625 C C + + C C PGF +G +CE+ E C N C + ++C+DL F+C C SG CE + V+ C + C+H G CRD +C C +G+EG DC C PC GVC + G+ C C+ F GI C Sbjct: 31 CFNGGRCADDAEGGGYSCHCPPGF--SGFNCEKKAEHCSSNPCA-NGAQCLDLEATFKCRCKPGFSGNRCE-MNVDDCGRQPCLHGGTCRDLVNGFTCSCPTGYEGKDCGTPASYCQSGPCFNGGVCVLQGGDGGYACECRVGFGGIDC 175 HSP 2 Score: 52.373 bits (124), Expect = 6.061e-7 Identity = 42/121 (34.71%), Postives = 56/121 (46.28%), Query Frame = 1 Query: 5182 HFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-IC-----RDDNSCLCLSGWEGIDCNKSI 5523 H +SN C A C +L F+C C PGF GN CE +D+C CL C DLVN F C C + G+ C + C C +G +C +C C G+ GIDC + + Sbjct: 65 HCSSNPCANGAQCL--DLEATFKCRCKPGFSGN--RCEMNVDDCGRQPCL-HGGTCRDLVNGFTCSCPTGYEGKDCGT-PASYCQSGPCFNGGVCVLQGGDGGYACECRVGFGGIDCGELV 179 HSP 3 Score: 51.9878 bits (123), Expect = 8.635e-7 Identity = 51/160 (31.87%), Postives = 68/160 (42.50%), Query Frame = 1 Query: 5230 ELNDEFQCFCNPGFVGNG---SSCEEIDECLFNFCLGDSSRCIDLV--NDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI-CRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSE-NFGVCL 5679 +L +++ C C GF G SS D FN RC D + C C SG CE K C + C +G C D + C C G+ G C ++DDC PC G C D +NGF C+C + G C C++ N GVC+ Sbjct: 1 DLENDYSCVCPSGFFGKNCDMSSMSCDDTPCFN-----GGRCADDAEGGGYSCHCPPGFSGFNCEK-KAEHCSSNPCANGAQCLDLEATFKCRCKPGFSGNRCEMNVDDCGRQPCLHGGTCRDLVNGFTCSCPTGYEGKDCGTPASYCQSGPCFNGGVCV 154
BLAST of Protocadherin Fat 4 vs. Ensembl Nematostella
Match: EDO32436 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SV36]) HSP 1 Score: 122.094 bits (305), Expect = 1.330e-27 Identity = 194/834 (23.26%), Postives = 346/834 (41.49%), Query Frame = 1 Query: 235 NDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNV----------DANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGV---IYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNN---NSLSEIVKIIIL------NVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINE-LYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPS-TVTENIPSGSVIGKFSILDSNLNSTIEKCSL---QLITFNEIFLISQFQ-LELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYI--ENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISD-NSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIF-IFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLN---CNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG-----GLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLS------TYNQIECSIIKPLKWF 2586 NDPPTN+ LS + E+ VG+++G S +D + +V S S F++ D N N P+ + I D+ N + + E + + D+N+ P I ++ T N+N++ G+ +GV I +DP F T+ S + NL K L + Q+++ ++ TD N+ + V +I+ ++ P +K + S + + +L +I+ N L F+I I +EL++E F A + ++ + + I + +VNEAP + L + TV EN +G+++G F + D + T CSL T + F + LE+K ++YEKT + + TD G N+ T + + +++ NE P +S+++ +PEN P+G L+ ++ ++ DK N +T+D F + + +L D+E P I + D G L I I + N+ P I G V+ EN+ + I + + D D +C + D R VQ + I T + D+E++ I + +D K +I K F I V++VNE PT + + R+++ N + I TDPD N + ++ + ++ C+ +F +L L S+ D+ES G +++I D+ LS++ I++ D N+PPT + ++ +++ D DN TY I S + P + F Sbjct: 202 NDPPTNLTLSGNTLLEHAAVGTVIGTFSALDPQVGQEIVFNVTS-SLFSINGTKLQSTWQDPNLN----GPISLN-NGEVAITIRATDNGNPPMWREQEFKVRILDVNDPPGNISLSNH------TVNKNAQVGSLVGVFTAIDGDDPTATPSSNFTWELTNSSNGLFKLNGSNLVVAKPLNNVP-----------QNQIQIEVKCTDSGQPFENATQKFVIYLIMYDDYHASITYRPISVKEDASVGTTAGTLTATQSLALPVTLSINHLNNTVLEKFKIGATTCSITADTATCTADILVKSELDFEDKSTFTFTASANFSKGVV-TREFTITVKNVNEAPTDIYLNGTLTVPENAVAGAIVGSFLVTDPDKTQT-HNCSLVNSAQSTGSSYFTVENGTVLEVKGEPVINYEKTRHLAIKVTCTDDGDPNLSTTKDFNITVTNQNEPPLQVSITSQTVPENSPLGTLVGSLSCEEPDKLTNDNCTFTIDSQNYAFRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKG--GLYKKVKLQINITDQNDAPTGINLPGNGGDLSVY---ENSRSGTVISAIKLVDQD-GDPPSCSLTDDAGGRVAVQGTNLI--------TGSANSDFEESAVLHITLSCSDGK-VQSIQKSFNITVKDVNEVPTDITLS-HRQVLEN-----EANTRIGIITVTDPDVNQSHRCTVCDVIDEGRCDASADFIV-DERLQLLTSRGLDFES--GHIRRIVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSVCSSPFEQAIRASVGSVVARLSAVDPDNAGSVKQALTYKIITGSGVFPFQLF 986 HSP 2 Score: 110.923 bits (276), Expect = 4.150e-24 Identity = 185/798 (23.18%), Postives = 326/798 (40.85%), Query Frame = 1 Query: 1171 VNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIE-KCSLQLITFNEIFLISQFQ-LELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLV---YTLDVNEKD---FYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNE-------NPEIIIKDQYGNKTEVFHIMENNELEMTFATI------TVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFS-NGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECS-IIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNG--HTKIKSTTYSTALAIEDINNEPATFSF--NWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSN-QSI--NLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNEL-LTDVNSLDVVVSNYITYFWVEILCRDDG---QPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLA 3462 +N+ P LTL +T+ E+ G+VIG FS LD + I + L + N L S +Q L L+ + + IR TD G + + E + I D N+ P N+SLSN+ + +N +G L+ + A D D + +T ++ F + + L+ ++ + QI + D+G P N ++ F I ++ ++ P I +K+ T + L + TV E C I +D + D+ + LD+E + F N K + I V+NVNE PT + ++G+ + + EN + +F+ TDPD+ S++N F+ G+ L +K +YE IKV LS + I++ + N+PP + +P ++G ++ + D L+ N C+ I + L +V + + E IDI + + G + K+K + I D N+ P + N V ENS + ++ + + D S ++++ ++ + ++T + + E + ++ TL + QSI + + + DVNE P++I + + E N I TDPD NQ H + +I G + S IV+ L L LD S +I + I C D+ Q LS++ F I +I+VN+ PT++ AI+ A++ +V+A Sbjct: 201 LNDPPTNLTLSGNTLLEHAAVGTVIGTFSALDPQVGQEIVFNVTSSLFSINGTKLQSTWQDPNLNGPISLNNGEVA---ITIRATDNGNPPMWREQEFKVRILDVNDPPGNISLSNHTVNKNAQVGSLVGVFTAIDGDDPTATPSSNFTWELTNSSNGLFKLNGSNLVVAKPLNNVPQNQIQIEVKCTDSGQPFENATQKFVIYLIMYDDYHASITYRP-ISVKEDASVGTTAGTLTATQSLALPVTLSINHLNNTVLEKFKIGATTCSITADTATCTA------------DILVKSELDFEDKSTFTFTASANFSKGV-VTREFTITVKNVNEAPTDIYLNGT----LTVPENAVAGAIVGSFLVTDPDKTQTHNCSLVNSAQSTGSSYFTVENGTVLEVKGEPVINYEKTRHLAIKVTCTDDGDPNLSTTKDFNITVTNQNEPPLQVSITSQTVPENSPLGTLVGSLSCEEPDKLTNDN---CTFTIDSQNYAFRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKGGLYKKVK-----LQINITDQNDAPTGINLPGNGGDLSVYENSRSGTVISAIKLVDQDGDPPSCS-------LTDDAGGRVAVQGTNLITGSANSDFEESAVLHITLSCSDGKVQSIQKSFNITVKDVNEVPTDITLSHRQVLENEA---NTRIGIITVTDPDVNQSHRCTVCDVIDEGRC-DASADFIVDERLQLLTSRGLD-FESGHIRR--IVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSVCSSPFEQAIR--ASVGSVVA 953 HSP 3 Score: 98.9821 bits (245), Expect = 1.851e-20 Identity = 122/517 (23.60%), Postives = 228/517 (44.10%), Query Frame = 1 Query: 124 LNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDS---PFNVDANF-NLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTD-----SVEIKHKNELWIKESAELNYESSYVNYFVV----GAYKDQI-LIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDS-NLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFE---IILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEK 1620 +N+E KT ++++++ D P S ++ + + N+PP + +++ V EN +G+LVG +S + D + C+ DS F + ++ ++ LDYE + ++++ D K +I++TD N+AP I N L+ ENS+SGT I I D D + T+ I +FE + L+ +S +D S+ + I + +V+E PTD+ L + +VL EN +N +G ++ D D+N+ + + + + S + L + S L++ES ++ V+ A Q+ L K + I +IDVNE P + P GSV+ + S +D N S + + ++IT + +F F+ + D + + I+VTD G+ +VTD + +S N N SL+ ++ + L ++++ Q D ++L+ L + +K Sbjct: 586 INYE-KTRHLAIKVTCTDDGDPNLSTTKDFNITVTNQNEPPLQVSITSQTVPENSPLGTLVGSLSCEEPDKLTNDNCTFTIDSQNYAFRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKGGLYKKVKLQINITDQNDAPTGI--NLPGNGGDLSVYENSRSGTVISAIKLVDQDGDPPSCSLTDDAGGRVAVQGTNL-------------ITGSANSDFEESAVLHITLSCSDGKVQSIQKSFNITVKDVNEVPTDITL---SHRQVL--ENEANTRIGIITVTDPDVNQSHRCTVCDVIDEGRCDASADFIVDERLQLLTSRGLDFESGHIRRIVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSVCSSPFEQAIRASVGSVVARLSAVDPDNAGSVKQALTYKIITGSGVFPFQLFKNMIFKTA--DVIQPTNFTFSIQVTDDGR--VVTDVSPNGLTFNVSKPNTVVFNCSLAVTADFMSDALDLRPSVVSVQSRD--NSLIGRLSLPKK 1075 HSP 4 Score: 93.9745 bits (232), Expect = 6.151e-19 Identity = 163/782 (20.84%), Postives = 302/782 (38.62%), Query Frame = 1 Query: 2089 FVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNI-----GKDIKVLIRAIDSGGLSI--DLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNL-------EIVTTATRFIDEKFIDIEIQCFNNGHTKIKST-TYSTALAIED-----INNEPATFSFNWTV---DFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCH---GSNSY---FGISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWN----EKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTI--FRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNIN-------CEIFSDGNFFIIVDF------KVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLST----TINVTDVDEPLKEI 4278 F +N+PPT L + G+ + E+ I F DP I +++ + L FS G+KL +S + D N ++ + IRA D+G + + E + I D NDPP L+ + + ++G D D+ + W + N S L +V + + I IE++C ++G +T + L + D I P + + +V + +++L L + +N L+ K D ++ LD+E ++ F + + + + + +VNEAP++I LT+ E + + +F TDPD Q H+ +VN S V N + +V V+ + +++ C DDG P+LS F I + N N+ P ++ ++ + E++ + T++ E+ D C S +Y G S+ + LDYE ++ +VV D+ GL QI+I D N+ P + + + + E S G +I+ + D +G L +Q +++ + E+ L ++ SD ++ S +T+ E I++ + V+ N+ IG ++ P++N C++ +G DF ++L ++ LD+E+ + + C N LS I V DV+EP + Sbjct: 197 FCRRLNDPPTNLTLSGN-----TLLEHAAVGTVIGTFSALDPQVGQEIVFNVTSSL-------FSINGTKL---QSTWQDPNLNGPISLNNGEVAITIRATDNGNPPMWREQEFKVRILDVNDPPGNISLSNHTVNKNAQVGSLVGVFTAIDGDDPTATPSSN------FTW-ELTNSSNGLFKLNGSNLVVAKPLNNVPQNQIQIEVKCTDSGQPFENATQKFVIYLIMYDDYHASITYRPISVKEDASVGTTAGTLTATQSLALPVTLSINHLNNTVLEKFKIGATTCSITADTATCTAD--ILVKSELDFEDKSTFTFTASANFSKGVVTREFTITVKNVNEAPTDIY-LNGTLTVPENAVAGAIVGSFLVTDPDKTQTHNCS----LVNSAQSTGSSYFTVENGTVLEVKGEPVINYEKTRHLAIKVTCTDDGDPNLSTTKDFNITVTNQNEPPLQVSITSQ--TVPENSPLGTLVGSLSCEEPDKLTNDNCTFTIDSQNYAFRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKGGLYKKVKLQINITDQNDAPTGINLPGNGGDLSVYENSRSGTVISAIKLVDQDGDPPSCSLTDDAGGR---VAVQGTNLITGSANSDFEESAVLHITLSCSDGKVQSIQKSFNITVKDVNEVPTDITLSHRQVLENEANTRIG---------IITVTDPDVNQSHRCTVCDVIDEGRCDASADFIVDERLQLLTSRGLDFESGHIRRIVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSV 935 HSP 5 Score: 91.2781 bits (225), Expect = 3.939e-18 Identity = 168/699 (24.03%), Postives = 290/699 (41.49%), Query Frame = 1 Query: 352 CSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYT-KCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEI--VKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSL-GELSAIDED--INELYSFQILILHTDSVEIKHK---NELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPS----TVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTL-DV-------NEKDFYI-ENNKLLSGTVFDHENRPGYQITITVFDNG-DPK--LNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTIN---QTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPT-----KLAIDGS-REIIINITENIQGYQSIANFITTD---PDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDY 2331 CS+ +D+ ++ K+ LD+E ++ F + V + I+V ++NEAP IY+N T LT EN+ +G +G DPD+ T + + S NS + +T + T + ++ E N+E+ L +++ TD + +LS I + N +E P + + T + ENS +L G LS + D N+ +F I DS + + + + L+YE V VV A L I + D N+AP G+ L + +V EN SG+VI ++D + + CSL + + Q + + D+E++ ++ + +D ++I F I + D NE P +++LS+ Q+ ENE I II D D N + T+ DV DF + E +LL+ D E+ +I I DN P+ L+V K F+I +++ NE P + + F + A ++ +PD + + L K +F + L N +T D Q F +I++ D + NV++P T LA+ +++ ++ QS N + P + N+ KY LN +E F+ G ++++K DY Sbjct: 464 CSITADT---ATCTADILVKSELDFEDKSTF-TFTASANFSKGVVTREFTITVKNVNEAPTDIYLNGT-----LTVPENAVAGAIVGSFLVTDPDK-------TQTHNCSLVNSAQSTGSSYFTVENGTVLEVKGEPVINYEKTRHLAIKVTCTDDGDPNLSTTKDFNITVTNQNEPPLQVSITSQT-----VPENSPLGTLVGSLSCEEPDKLTNDNCTFTI-----DSQNYAFRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKGGLYKKVKLQINITDQNDAPTGINLPGNGGDLSVYENSRSGTVISAIKLVDQDGDP--PSCSLTDDAGGRVAV--QGTNLITGSANSDFEESAVLHITLSCSDGKVQSIQKSFNIT--VKDVNEVPTDITLSHRQVLENE-ANTRIGIITVTDPDVNQSHRCTVCDVIDEGRCDASADFIVDERLQLLTSRGLDFESGHIRRIVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSVC-------SSPFEQAIRASVGSVVARLSAVDPDNAGSVK--------QALTYKIITGSGVFPFQLFKNMIFKTADVIQPTNFTFSIQVTDDGRVVTDVSPNGLTFNVSKPNTVVFNCSLAVTADFMSDALDLRPSVVSVQSRDNSLIGRLSLPKKFPNETFKY----LLNSDETVPFAINGDQVFVKSIAMKDY 1110 HSP 6 Score: 88.9669 bits (219), Expect = 1.941e-17 Identity = 187/810 (23.09%), Postives = 327/810 (40.37%), Query Frame = 1 Query: 1480 NERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRP------GYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEP-DFDDKINCQIISDNSRFLVQKKSEIKNIFQYD---LTINQTLDYEQNNYFEINIEIND----MKNFTAIMKIFIFV-----ENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTM-IPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLK-----WFSILNISQNLEIVTTAT-RFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDN-SFMLTDPLDYETENNFLISFTLIDKNS-NQSINLKVQILDVNEAPSEI--KSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQC-----------HGSNSYFGISNSSIYIAKRLDYETFTKMETIVVCFD-----QSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPE 3765 N+ P NL+LS N + E+ +G +I +A D +V+ +V F I KL S + N P ITI DNG+P + + F + IL+ N+ P GN + H + N + + VF D DD + +S F + + +F+ + L + + L+ N +I ++ D +N T I++ + ++ P + D S + + QS+A +T + N V++ + C+ + + + + +K F+ +S A S G+ + E I++++ N+ PT LN T+ +P I+G V D D T+N CS++ + +F++ N LE+ + + + I++ C ++G + STT + + + N P S T V ENS LG L+ + + + S N ++ D S ++ LDYE E I DK + + L++ I D N+AP+ I +L+++E S I+ D D D + + V+ N L+T + D S + + C D SIQ F I + +VN+ PT I L+ ++ AN T + I + D D + H+C S + + ++ LD+E+ ++ C D Q L+V F I + DVNEPP +V S + ++ +G ++A LSA DP+ Sbjct: 202 NDPPTNLTLSGNTLLEHAAVGTVIGTFSALDPQVGQEIVF--NVTSSLFSINGTKLQSTWQDPNLNGPISLNNGEVAITIRATDNGNPPMWREQEFKVRILDVNDPP--------GNISLSNHTVNKNA--QVGSLVGVFTAIDGDDPT----ATPSSNFTWELTNSSNGLFKLNGSNLVVAKPLNNVPQNQIQIEVKCTDSGQPFENATQKFVIYLIMYDDYHASITYRPISVKEDAS---VGTTAGTLTATQSLALPVTLSINHLNNTVLEKFKIGATTCSITADTATCTADILVKSELDFEDKSTF----TFTASANFSKGV-VTREFTITVKNVNEAPTDIYLNGTLTVPENAVAGAIVGSFLVTDPDKTQTHN---CSLVNSAQSTGSSYFTVEN-GTVLEVKGEPVINYEKTRHLAIKVTCTDDGDPNL-STTKDFNITVTNQNEPPLQVSI--TSQTVPENS---PLGTLVGSLSCEEPDKLTNDNCTFTIDSQNYAFRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKGGLYKKVKLQINITDQNDAPTGINLPGNGGDLSVYENSRSGTVISAIKLVDQDG------DPPSCSLTDDAGGRVAVQGTN--LITGSANSDFEES---AVLHITLSCSDGK--VQSIQKSFNITVKDVNEVPTDIT-LSHRQVLENEAN--TRIGIITVTDPDVNQSHRCTVCDVIDEGRCDASADFIVDERLQLLTSRGLDFESGHIRRIVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSVCSSPFEQAIRASVGSVVARLSAVDPD 961 HSP 7 Score: 80.8777 bits (198), Expect = 5.217e-15 Identity = 113/486 (23.25%), Postives = 202/486 (41.56%), Query Frame = 1 Query: 217 VAILDANDPPTNIQL-SNWKVEENILVGSLVGQISVVDEDLDDSFKCSV------KSDSPFNVDANFNLFTKAP--LDYETQARFEVIIECLDH--ENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDR--NDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDEN--PTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSL-QLITFNEIFLISQF----QLELKDNTRLDYEKTPAYNLGIRVTDYG---QENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTL 1605 + + + N+ PT+I L V EN + G++VG V D D + CS+ S F V+ L K ++YE + + C D N S I+VT+ NE P ++ + + T ENS GT +G + C +PD+ ND F +S + Y L + + + + E I V + L + VK+ I D+N PT + L + + + E + S + + +D+D + S + V ++ N I SA ++E S V + + ++ K++ I + DVNE P +TL V EN + + IG ++ D ++N + +C++ +I + F +L+L + LD+E + I TD Q + + + + D NE P ++ S + +G ++A ++A D D ++ L Sbjct: 510 ITVKNVNEAPTDIYLNGTLTVPENAVAGAIVGSFLVTDPDKTQTHNCSLVNSAQSTGSSYFTVENGTVLEVKGEPVINYEKTRHLAIKVTCTDDGDPNLSTTKDFNITVTNQNEPPLQVSITSQ------TVPENSPLGTLVGSLSCEEPDKLTNDNCTFTIDSQN--------------YAFRLGSDGKSVLVNGSLDYEVEPVIDIVVVATDKGGLYKKVKLQINITDQNDAPTGINLPGNGGDLSVYENSRSGTVISAIKLVDQD-GDPPSCSLTDDAGGRVAVQGTN--LITGSANSDFEESAVLHITLSCSDGKVQSIQKSFNITVKDVNEVPTDITLSHRQVLEN-EANTRIGIITVTDPDVNQS-HRCTVCDVIDEGRCDASADFIVDERLQLLTSRGLDFESGHIRRIVINCTDNATSPQMPLSVEKAFNITVIDVNEPPTSVCSSPFEQAIRASVGSVVARLSAVDPDNAGSVKQAL 970 HSP 8 Score: 51.2174 bits (121), Expect = 5.670e-6 Identity = 36/113 (31.86%), Postives = 57/113 (50.44%), Query Frame = 1 Query: 151 ISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDS-------FKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLD 468 +++ I A D P + V ILD NDPP NI LSN V +N VGSLVG + +D D + ++ + S+ F ++ + NL PL+ Q + ++ ++C D Sbjct: 275 VAITIRATDNGNPPMWREQEFKVRILDVNDPPGNISLSNHTVNKNAQVGSLVGVFTAIDGDDPTATPSSNFTWELTNSSNGLFKLNGS-NLVVAKPLNNVPQNQIQIEVKCTD 386
BLAST of Protocadherin Fat 4 vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 98.2117 bits (243), Expect = 3.248e-20 Identity = 187/828 (22.58%), Postives = 348/828 (42.03%), Query Frame = 1 Query: 91 SMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWK--VEENILVGSLVGQISVVDEDLDDSFKCS---VKSDSP-FNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKH--EISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIII--LNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDED--INELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLI--DVNEAPQGLTLYPSTVTENIPSGSVIGKFSI------LDSNLNSTIEKCSLQLITFN--EIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDAN------ERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLL--SGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMEN--NELEMTFATITVFEPDFDDKINCQIIS--DNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND--MKNFTAIMKIFIFV--ENVNEP----PTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGG--LSIDLEVPISIQDAND 2436 S E PL+ E+K ++ ++ I A D F+ + + D ND LS +K V E++ VGS+V Q++ VD D+ + + S V D+ F VD+ + TK D ET+A ++V + D + S + EI + D+N+ ++ ++ + + +E+ G + + +D D N+ D+ + + +T + + +FE++S +SVTDR + L++ ++I ++++NP + ++ + ++EN+ + ++SA D D N F I+ + D V + I + +YE+ V A + + T + + DVN+ PS ++ IP +VIG + LDS +E +LI+ N F I ++ ++ LD E TP+Y+L + D G + + + + + D N + P +S + P ++ IG + A D+ N + Y L N F I + L T D+E + Y +T+T D G P + + + + N+NP K Y + EN + + + T T + + KI+ I+S +N F + + F ++T LD E + + I +D + F A + I + EN N+P P++ NI+E+ + TD D N + Y+I++ N F+ L ++ + D E+ ++++A D+G SI + +S+ D ND Sbjct: 119 SKTGEIRTVTPLDHETK-DSYTMRISAFD----GKHTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDN-RPVF---SSAQYTASVDEDVAIGAAMVTVTASDKDNG-------NNADLRYSFTSGNTNHAFTLDAVTGV-VTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNP---PVFSPSAYQSRVKENTPAGT--QVSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVND--HSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLE---YRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSESSSPGHQ-IGQVAA--TDADDSSNGDVRYALSDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLY-----TCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDR-------FTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRF----------NISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISG-NQGNSFQLDPRSGILSVRST--LDRETI--PSYTLVVKASDAGSPQQSITASIHVSVLDVND 889 HSP 2 Score: 79.7221 bits (195), Expect = 1.254e-14 Identity = 183/814 (22.48%), Postives = 338/814 (41.52%), Query Frame = 1 Query: 1141 NKTYFIQLIDVNE----APQ-GLTLYPSTVTENIPSGSV-IGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLS--NNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNK--LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMKN--FTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSID---LEVPISIQDAND-PPTVAGLNFT-MIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQC-FNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKI-QINEDNSFM-LTDPLDYETENNFLISFTLIDKNSNQSINL---KVQILDVNEAPSEIKSFEKNL---TMFEKSPPNIHIATFYATDPDY-------------NQIHSFDIQKIIVNGEIFNHSIV--KIVNNELLTDVNSLDVVVSNYITYFWVEILCRD--DGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTA 3426 +K + +IDV + AP+ L Y + EN P+ V I + DS N+ I + L + F+++ E++ T LD+E +Y + I D G+ T F ++ + D N+ +LS + E+ +G ++ + A D D N+ L Y+L + ++ +++ + + FD E + YQ+ + D G P + T +IEIL+ N+N + QY + ++ + A +TV D D+ N + R+ + F D +T++++LD+EQ + + + + + D + T + I V ++N+ P + + + EN ++ TD D N + + I + N+ F+ GS + ++ DYE+ D+ V R G+ + +V I I+D ND P + N++ IP + V D D+ ++E +I NI N + ++ E +Q +G + +S++ +A++DIN+ F + +S +GQ + TD + S + +S+N + IN + L LDYE + ++++ T D + +L KV + DVN+ P + F K+L T+ E + + ATD D N+ +F + + GEI + + + + LT +N+ D + ++ V I D D QP+ + SRF I D PT + +LTA Sbjct: 50 HKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQVAIVTATDRDSGTNAAI---TYSLFSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFD-GKH---TTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVD-------EDVAIGAAMVTVTASDKDNGNNADL-----RYSF-TSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQS---RVKENTPAGTQVS---ATDRDSSTNGALVFGI---IKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQAR---DRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDS-GPRGRLEYRLISG-NVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSESSSPGHQIGQ-VAATDADDS----SNGDVRYALSDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQ---FAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRF--TGEITTRVPLDRETIASYSLT-INADDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNIS----EDSPTGTR-VGQLTA 813 HSP 3 Score: 69.707 bits (169), Expect = 1.355e-11 Identity = 158/686 (23.03%), Postives = 281/686 (40.96%), Query Frame = 1 Query: 109 SISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND--PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDD----SFKCSVKSDSPFNVDANFNLFT-KAPLDYETQARFEVIIECLDH--ENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNY------SLGELSAI------DEDINELYSFQILILHTDSVEIKHKNE-LWIKESAELNYES--SYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQ--GLTLYPSTVTENIPSGSVIGKFSILDSNLNS-TIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTD--YGQENIVTDFEIIL-EISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKD---FYIENNKLLSGT--VFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQI---ISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND 2052 S++ L+ E+ T N +L + A + S + +LD ND P N + EN+ +G V +++ D D + +++ SV S F V+ L T K PLD E QA + + + +DH + S + +++ D+N+ + + + LT EN+ +G+ I + +DPD + + N + T RI + E + IS D + I DEN N + N ++Y S+G A+ DE N + I+ T + I N L +K+ E+N E+ +Y ++ +K + + DVN+ P Y +V EN + + + DS++ + + + S+ + F I+ + T LD+E+ Y L + TD Y + VT I L +I+ A + +N + S + EN P + ++A D D +L Y++ V KD F I+ + T V D E Y I + V D G+P L+ I+IL+ N+N ++ + + I+EN+ +F+ + D D+ N +I +S N F++ S + +T+ Q LD E + +++ I+ D Sbjct: 1052 SVAKRLDRET-TANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQF----SQSKYTLTVTENTANGSNILRVLASDPD--------AGANGRVTYSIISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADEN----------DNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVLTVKK--EINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDSKYTAKTNVTIRVINLNDITPAFTQ-QNYTAS---VRENSPTSTSVVKVSASDRDSFGSLSYSI-VGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDN-----SPKFDSSSYSSSILENS-APSSFS-FKLAATDADEGTNARITYNLSRNDAFMIGASSGV-------ITLAQPLDRENKSTYDLAIQARD 1693 HSP 4 Score: 63.1586 bits (152), Expect = 1.397e-9 Identity = 135/584 (23.12%), Postives = 246/584 (42.12%), Query Frame = 1 Query: 157 LEILAKDLDVPKNSKLFIIHVAILDAND--PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDS---FKCSVKSD-SPFNVDA-NFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVT--DINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPD-------------RNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEI-VKIIILNVDENPTDLKLNDSTSNKVLIEENS-SNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIF--------NKTYF-IQLIDVNE-APQ-GLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPE-NLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKD--FYIEN--NKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNEN 1779 L I AKD VP + + + D ND P +++ ++E + +GS V ++ D D + F V+ D S F ++A N L K ++ ET + + I D + + + E++V D+N+ P ++ I + ENS T + + +D D ND F NST I +FE +S+ +++ TD + + + +++I LN D P + N + S + ENS ++ S+ ++SA D D S+ I V K ++ I + + + + ++ +V Y Q+ + N T+ I+++D N+ +P+ + Y S++ EN S K + D++ T + + L + N+ F+I + LD E Y+L I+ D+G + I + + D N+ RP N S + EN+P + I A D D N+ L ++L NE F ++N + + D E + Y + I V D G+P L+ I++++ ++N Sbjct: 1276 LTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVF----NSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSGV---------------------IMTTTPLDFEEKSQYGLEVTATDSKYTAKTNVTIRVINLN-DITPAFTQQNYTAS----VRENSPTSTSVVKVSASDRDSFGSLSYSI-------VGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDAD-EGTNARITYNL-SRNDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDN 1820 HSP 5 Score: 59.3066 bits (142), Expect = 1.945e-8 Identity = 165/731 (22.57%), Postives = 283/731 (38.71%), Query Frame = 1 Query: 1369 RLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIENNK---LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPD--FDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMK----NFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGG--LSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVN------------VFDEDNLSTYNQIECSIIKP--LKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLT-DPLDYETENNFLISFTLIDKNSNQSINL---KVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPD--YNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKE 3435 RLD E T Y L +R T+ G + + + D N+ N + EN PIG +A + A D D+ N+ + Y L V + + N + + D E++ Y + +T D+G P + + I + N+N + +Y + EN + +PD + ++ IIS N N F+ D +T+ +D E + + I D TA + I + EN N P I S E I E + +A TD D+ N + YSI+ NG L +K+ + + IRA D G ++ D E+ + + D ND P P F + + IG V D+ ++ + SII K F I N + + + TT F ++ +E+ ++ +T K+ + + DI PA N+T V ENS ++ S++ S S IV ++ K I++ + + T D LD E + + I + D + NL ++ILD N+ + S + ++ E S P+ ATD D N ++++ + N + + ++ ++T LD N TY + I RD G P + + +I++ND IN + +++E Sbjct: 1056 RLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKY-----TLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNH----------GNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSP-----IFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNG--VLTVKK----EINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNP----------PVFNSQSY-IGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKI-NSTSGVIMTTTPLDFEEKSQYGLEVTATDSKYTA-KTNVTIRVINLNDIT--PAFTQQNYTAS-VRENS---PTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSR--------NDAFMIGASSGVITLAQPLD--RENKSTY-DLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRE 1730 HSP 6 Score: 54.6842 bits (130), Expect = 5.626e-7 Identity = 38/129 (29.46%), Postives = 63/129 (48.84%), Query Frame = 1 Query: 154 SLEILAKDLDVPKNSKLFIIHVAILDAND--PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDD----SFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDIN 522 +L + A D P+ S IHV++LD ND P L + ++ E+ V S V Q+ V D+D + S + F +D+ + +K PLDYET A +++ + D + S ++ +T IN Sbjct: 861 TLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSDNFTIDSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIIN 989
BLAST of Protocadherin Fat 4 vs. Ensembl Nematostella
Match: EDO36196 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJC3]) HSP 1 Score: 91.6633 bits (226), Expect = 1.750e-19 Identity = 67/174 (38.51%), Postives = 92/174 (52.87%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVCLNLKNK 5694 SN C TC N+L + + C C PG+ NG++CE +I+EC N C+ + C DLVN F C C +G CE+ +N C + CV+G C D SC C+SG+ G+ C I++C +PC G C D +NGF C C + G CE D C+ N N G C + N Sbjct: 83 SNPCLNGGTC--NDLVNGYNCKCQPGY--NGTTCEIDINECASNQCV-NGGTCTDLVNGFNCTCPPGYNGTKCEI-NINECENNPCVNGGTCADQVNSFSCTCVSGYTGLKCETDINECASNPCVNGGTCTDLVNGFHCTCPPGYNGTKCEIDINECESNPCANGGTCADQVNS 250 HSP 2 Score: 77.411 bits (189), Expect = 1.011e-14 Identity = 57/160 (35.62%), Postives = 77/160 (48.12%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDE---FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 C N N+C N D+ F C C G+ G CE +I+EC N C+ + C DLVN F C C +G CE+ +N C + C +G C D SC C+ G+ G+ C ID+C +PC G C + +NGF C C + G CE D Sbjct: 150 CEININECENNPCVNGGTCADQVNSFSCTCVSGYTG--LKCETDINECASNPCV-NGGTCTDLVNGFHCTCPPGYNGTKCEI-DINECESNPCANGGTCADQVNSFSCTCVLGYTGLKCETDIDECASNPCINGGTCTELVNGFKCTCVPGYNGTRCEID 305 HSP 3 Score: 75.8702 bits (185), Expect = 2.702e-14 Identity = 52/137 (37.96%), Postives = 71/137 (51.82%), Query Frame = 1 Query: 5296 EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKN 5691 +I+EC N C+ + C DLVN F C C +G CE+ +N C + C +G C D SC C+SG+ G+ C I++C +PC G C D +NG+ C CQ + G CE D C N N G C +L N Sbjct: 1 DINECASNPCV-NGGTCTDLVNGFHCTCPPGYNGTKCEI-DINECDSNPCANGGTCADQVNSFSCTCVSGYTGLQCKTDINECASNPCLNGGTCNDLVNGYNCKCQPGYNGTTCEIDINECASNQCVNGGTCTDLVN 135 HSP 4 Score: 72.7886 bits (177), Expect = 2.710e-13 Identity = 57/159 (35.85%), Postives = 79/159 (49.69%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN 5652 SN C TC +L + F C C PG+ NG+ CE +I+EC N C + C D VN F C C S +G C+ +N C + C++ G C D +C C G+ G C I++C + C G C D +NGF C C + G CE + C+N Sbjct: 7 SNPCVNGGTCT--DLVNGFHCTCPPGY--NGTKCEIDINECDSNPCA-NGGTCADQVNSFSCTCVSGYTGLQCKT-DINECASNPCLNGGTCNDLVNGYNCKCQPGYNGTTCEIDINECASNQCVNGGTCTDLVNGFNCTCPPGYNGTKCEININECEN 159 HSP 5 Score: 69.3218 bits (168), Expect = 4.266e-12 Identity = 54/151 (35.76%), Postives = 73/151 (48.34%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 SN C TC +L + F C C PG+ NG+ CE +I+EC N C + C D VN F C C +G CE ++ C + C++G C + C C+ G+ G C ID+C +PC C D LN + C C F G CE Sbjct: 197 SNPCVNGGTCT--DLVNGFHCTCPPGY--NGTKCEIDINECESNPCA-NGGTCADQVNSFSCTCVLGYTGLKCET-DIDECASNPCINGGTCTELVNGFKCTCVPGYNGTRCEIDIDECSSNPCLNGATCSDLLNNYTCTCASGFQGERCE 341
BLAST of Protocadherin Fat 4 vs. Ensembl Nematostella
Match: EDO49614 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFK1]) HSP 1 Score: 95.1301 bits (235), Expect = 2.331e-19 Identity = 64/173 (36.99%), Postives = 88/173 (50.87%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG----ICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKN 5691 S+ C C+S L D+F+C C GF G CE E DECL + C S CID VN ++C+C + SG C+V+ LC S C +G +C C G+ G+ C + +D C+ PC G+C + F CNC+ F+G CE D C KN N G C++ N Sbjct: 1041 SSPCQNGGRCES--LKDDFRCACPGGFTGR--RCETEQDECLSDPCY-QGSTCIDKVNGYECICAAGYSGPNCDVIS-GLCSSSRCQNGAKCVAKPPSGACECPEGYGGLFCERKMDFCVSAPCKNGGLCRSLQDKFQCNCRPGFSGDRCEIDIDDCAKNPCLNNGACVDQVN 1207 HSP 2 Score: 63.1586 bits (152), Expect = 1.481e-9 Identity = 47/151 (31.13%), Postives = 79/151 (52.32%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC 5625 +S++C A C + + C C G+ G CE ++D C+ C + C L + FQC C SG CE+ ++ C K+ C++ G C D +C C +G+ G C++++D+C +PC GVC++ +NG+ C C ++G C Sbjct: 1116 SSSRCQNGAKCVAKPPSGA--CECPEGY--GGLFCERKMDFCVSAPCK-NGGLCRSLQDKFQCNCRPGFSGDRCEI-DIDDCAKNPCLNNGACVDQVNGYTCTCKAGFAGSRCDRNVDNCYPNPCV-NGVCKNKVNGYECACNPGYSGSTC 1259
BLAST of Protocadherin Fat 4 vs. Ensembl Nematostella
Match: EDO39230 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAP5]) HSP 1 Score: 93.9745 bits (232), Expect = 8.161e-19 Identity = 171/724 (23.62%), Postives = 293/724 (40.47%), Query Frame = 1 Query: 253 IQLSNWKVEENILVGSLVGQISVVDEDLDDSFK---CSVKSDSPFNVDANFNLFT-KAPLDYETQARFEVIIECLDHEN--SSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPD--RNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINE-LYSFQILILHTDSVEI-----KHKNELWIKE----SAELNYESSYVNYFVV----GAYKDQILIFNKTYFIQLIDVNE-APQ-GLTLYPSTVTENIPSGSVIGKFSILDSN--LNSTIEKCSLQLI-TFNEIFLISQFQLELKDNTRLDYEKTP-AYNLGIRVTDYGQENIVTDFEIILEISDANERPENLS--LSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDV----NEKDFYIE--NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKT--FDIEILNSNEN-PEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQT----------LDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNE------PPTKLAIDGSREIIINITENIQGYQSIANFITTDPD---QNDVIKYSILN 2250 I N +V EN + V + +D+D + + +K + F +DA+ + T K LD E +++V + D N S+++ I+V D N+ P + ++ E+S GT + IY D D N + ++ + D + S + E+ + +L +FE +S +++ TD S + +V + I +V++ P + S + I+EN+ G + DI+ SF + D +I +W+ + S +L+ E S V F V G + Q I + L DVN+ AP+ + Y V EN PSG+ + +D + L K S +L + + F I +K D E+TP + + ++ TD G + + I+ +SDAN+ + + EN P G + + A D D + V + FYI+ N +L + D+E + Y IT+TV D G P L +T IEIL++N+N PE I K +++ ++ +TV D D N N F + +S+ + F + N LD E+ F + + D ++ I V +VN+ PP + I E + Q + DPD ++ VI +SI N Sbjct: 2574 INTRNARVLENKPAPTKVISMKAIDDDGSEPHRRVTYEMKDNPNFQIDASTGMITTKTTLDREVTPKYDVEVTAKDGVNKESAIL---YITVVDQNDQPPVF----APKSYAISVPEDSPIGTSVLDIYATDADVGENAKITYFISKGDPEGKFSIVT------SPVKGELVVNGKL--DFETKSSYTLEVTATD-GKFSDTAVVTVTIQDVNDLP---PVFSSPLYESRIQENTGP-GAGVVMVTASDIDSPTISFSLDDRGKDYFQITPIRASGPGNVWVGDIRTGSKQLDREESPVKVFTVIANDGKHTAQAEIR-----VNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSYELTDSAGDKFSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAGNPRLSASVDGIIHVSDANDHKPKFTEKFYRGSVAENAPPGYSVLRVTATDEDVGPNAEFEFVVVQGNDPHAFYIDPFNGTVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYVVIEILDANDNAPEFIPK--------IYNASVLEDVGARQPVLTVTAVDKDSGPNG-----NFTFAIDPRSDPDDAFTIEPNPNNASIGIIRTRVPLDQEKTPSFHLKVTATDAGGLQGEGEVRINVIDVNDNGPWFVPPF---------FVGQIKEGVSARQFVTKLKAYDPDAFVKDQVITFSIYN 3250 HSP 2 Score: 66.6254 bits (161), Expect = 1.458e-10 Identity = 179/859 (20.84%), Postives = 349/859 (40.63%), Query Frame = 1 Query: 1363 NTRLDYEK-TPAYNLGIRVTDYGQENIVTDFEIILEISDANER-PE-NLSLSNNQIPENEPIGLLIAIINAQDNDKNST-------LVYTLDVNEKD---FYIE--NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPD--QNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLE-------VPISIQDAND--PPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDE--KFIDIEIQCFN----NGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS--NQSINLKVQILDVNE-APSEIKSF-EKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKI-VNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINT----VLAXXXXXXXXXXXXHQCHGSN--SYFGISNSSI----YIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPE--NVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLN 3792 N+ LD+E+ YNL ++ T+ + + + ++ +++ +AN+ P + L + QIPE+ +G+L+ + A+D D S+ L Y+++ +++ FYI+ K+ D+E++ + + + D G ++ + N N+N +K Y F + E + A + + D D + +F V + + + +T+N LD +N Y + + D T+ + + V + N + G+ ++I EN I TD D QN I YSI + + + FS ++ D E+ +I+A D + E + I+++D ND P +A F + S I V D D+ S +I+ +++ L+ S L T R E K + +E+ + G K T Y+T + I N EP FS + EN S + +T S+ +IS ++ I ++ D + D DYE + + F DK + ++ + + I+DVN+ +P+ + + +N + E P + + A D D ++ H V E+ ++ +I + ++T +LD V+ + VE+ +D +I YI +++ ND P + ++ E + I T + A E+ + + F I S + + +LD+ET + T+ V + ++V + I+DVN+ P + + + E + G + ++A+D + + F L+ Sbjct: 1994 NSLLDFERDQTQYNLKVKATEQIPDGLDSTVDVKIDVINANDHFPYFDQQLYSVQIPESTAVGVLVQEVTAKDCDCLSSCTCSPGFLTYSIEPSKEQGGKFYIDPATGKISVSVALDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDNRPTFLKSAY-----EFRVAEGAATGESLAIVVAVDAD-GDAVTYSKAGGALQFSVDQSTGV-------ITLNSALDPNKNQY-TLQVMAKDSGGLTSTVSVTFNVADANNNVPQFTNCGT----VSIRENDPRDTKITQLTATDADRGQNGQITYSIEDA---SSQTLFSIEPRTGVVRSLTSLDRENK--DSYNAIIKAEDGSSKQDESERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAPNGSNILTVQATDADSGSN-AKIKYALLDSAGGLFRLDSSGILRTNTNPARLQLETGKKLLLEVSAKDVESIAGTQPGKPTKYTTQIEILVSNEEPPKFSQQVYTASINENMETGS--TVTRITATSSTGAEISYENVDTNPRAKILFRVQPDGYIITGDRPDYERGTTYNMQFAAKDKKTLLYSTVKVVINIIDVNDVSPAFLLAINTRNARVLENKPAPTKVISMKAIDDDGSEPHRR------VTYEMKDNPNFQIDASTGMITTKTTLDREVT---PKYDVEVTAKDGVNKESAI---LYITVVDQNDQPPVFAPKSYAISVPEDSPIGTSVLDIYATDADVGENAKITYFISKGDPEGKFSIVTSPVKGELVVNGKLDFETKSSY-TLEVTATDGKFSDTAVVTVTIQDVNDLPPVFSSPLYESRIQENTGPGAGVVMVTASDIDSPTISFSLD 2813
BLAST of Protocadherin Fat 4 vs. Ensembl Medaka
Match: ENSORLT00000005325.2 (protocadherin-16 [Source:NCBI gene;Acc:101171352]) HSP 1 Score: 107.071 bits (266), Expect = 1.914e-22 Identity = 164/694 (23.63%), Postives = 293/694 (42.22%), Query Frame = 1 Query: 1219 ENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNT-------RLDYEKTPAYNLGIRVTDYGQENIVTDFEIIL-EISD-ANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKD----FYIENNK---------LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDL-----TINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVE----NVNEPPTK---LAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYL-KESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQ--DAND-PPTVAGLNFTM-IPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATR--FIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQ--INEDNSFMLT-DPLDY-ETENNFLISFTLIDKNS-NQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQ 3162 E P+G+++G S + L E L I+ +E + L++ + T RLD E+ Y+ I VT G I + I + +I+D A E P+ +L +IPE+ +G ++ A D DK+ + E + F +E+ + L+ + D E R Y + I FD G P+ T ++ + + N++ + + +Y H + + L + + VF D D+ N ++ + +R ++S+ + F DL T+N+ LDYE E+ ++ D + + F+ + N N+P L+ DGS I+E Q Q +A TDPD + ++ + + KF + S +YL Q D E D++V+ A DSG + E +IQ D ND PP + IP V + +V D+D + S++K KWFSI I+ I+TTAT F E + + + G + S+T + ++D+N+ FS N+ V EN+ + + TD S ++ + ++ IN+ + T LD E + ++ T D + ++ ++V+++D+N+ +++ S P + A DPD + Sbjct: 37 EGQPAGTIVGDIS---AGLPPG-ETARLYFISDHEGTGVGS-DLDIDETTGIITTKRRLDREERDHYSF-IAVTMTG---ITIEVSITVNDINDHAPEFPKKKALL--KIPEHTVVGTRFSLDPATDADKDQLTTQGYAIKEGNVGHMFKLESKRSANKVLYLDLVVSGLLDREKRSSYSLVIEAFDGGSPRRVGFMTLEVTVTDINDHAPVFNQSRY-------HAIISESLPQGSSILQVFAADEDEGDNGLVLYEINR----RQSDPERYFVIDLKSGVITLNRPLDYELKRVHELVVQARDNASQPEVTNAFVTIHVRDFNDNQPTMTIIFLSEDGSPR----ISEGAQPGQYVARISVTDPDYGEYANVNV-SLEGGDGKFALTTKDSIIYLIYVDQVLDREERDSYDLRVM--ATDSGTPPLRAESSFTIQVTDVNDNPPLFDQQAYRQTIPEVVYPGSFVLQVTARDKDQ-GPNGDVRYSLLKGKKWFSIDPITG---IITTATALDFESEPAPSVTVIATDGGRPPL-SSTAKVDIVVQDVNDNAPVFSSNFYNVSVKENTPAGTCFLEVSATDEDRGSFGTITYALTLKSGGTVQTPFTINKQTGQLCTASALDRDEGLEKYDLTVTATDGGGLSSAVGVRVKVMDINDNRPTFYPVLYTVSLSTHSAPGTSVVKVTANDPDAGE 696 HSP 2 Score: 90.5077 bits (223), Expect = 2.312e-17 Identity = 153/683 (22.40%), Postives = 280/683 (41.00%), Query Frame = 1 Query: 211 IHVAILDAND--PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVK---SDSPFNVDANFN-LFTKAPLDYETQARFE--VIIECLDHENSSVINKHEISVTDINE-APDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEI-------KHKNELWIKESAELNYE--SSYVNYFVVGAYKDQILIFNKTYFIQL-IDV----NEAPQGLTLYPSTVT--ENIPSGSVIGKFSILD-------SNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYG---QENIVTDFEIILEISDANERPENLSLSNN-QIPENEPIGLLIAIINAQDNDK--NSTLVYTLDV--NEKDFYIENNKLLSGTV-----FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDM---KNFT-AIMKIFIFVENVNEP 2112 + V + D ND P + + V EN++ G+ G++S D D + + + + +D F +++ + T+ LD E Q+ ++ V+++ S ISV D N+ AP +V E M E SGT +G + DPD + N T V S + E++ L + ++E F ++ D LS +I I + + + K N + ++E + +G + +D+ + + Q+ L D + + + ++++ EL+YE SSY + V + F +Y ++L I+V + APQ + P T+ EN G+ I F D S L +IE Q +++ + L +LD E TP L +R TD + L + D N+ P S + + E++P+G +I + A D D+ N + Y + N F + N +G++ D E + + +TI D+G P+L+ S+ +++++ N+ + + ++G H+MEN T +T D D N I V + + N +T + LD E N++ + + D NF A++++ + N N P Sbjct: 1084 VRVTVTDENDNSPRLSQERVFLAVRENLVAGTGFGRVSATDRDAGLNARLTYRLLHADKHFQINSQTGEISTRLALDREQQSSYQLFVVVQDGGTPPRSATGTAHISVLDENDHAPTFTHVRPDTERM-FEVREGLPSGTMVGSVAAKDPDEGE------NGT-VYYSLSGSRVERFSLNPNTGELKTASPL--RWAERAEYTFTLTAADHGTPGLSSTCQIRIQVISSSRSIPKPNVLSMTLNVVEGTAPGSIIGSVGQVDKPESNVLEGQVTYLVVDGTDRDGTFMVDRLRGDVYLVR--ELDYEKGSSYTLHVEVSDFSK---AFPNSYLVKLEINVQDSNDHAPQ-FSEDPVTIVIPENKEPGASIYAFQAGDQDGSGPNSELRYSIEH---QWPQTSDLLALDPLSGVLTIRQQLDRESTPFLYLVVRATDQAVDLSQRRWGSVTARLFVKDENDNPPVFSSPSAISVMEDQPVGFVILHVMAHDADEGENGRVSYRIQSGNNAGRFSLSPN---TGSLSILKALDREEQEVFNLTIVAEDHGIPQLSTSQVLCVQVIDVNDEAPMFQQAEFGT-----HVMENKGPGTTVLKVTAT--DRDQGSNGHITYGG----VTEDGFVINPLTGVITTTKELDAELQNHYVLTVYARDGGLPPNFAKAVVRVEVQDVNDNAP 1733 HSP 3 Score: 65.0846 bits (157), Expect = 1.216e-9 Identity = 157/746 (21.05%), Postives = 277/746 (37.13%), Query Frame = 1 Query: 97 CWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND--PPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVK--------SDSPFNVDA-NFNLFTKAPLDYETQARFEVIIECLDHENS---SVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFE-----------------LGFNFERQSELYFQISVTDRNNN-----SLSEI-------VKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSL----GELS---AIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVN-EAPQ-GLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEI----FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLS--LSNNQIPENEPIGLLIAIINAQDNDKN--STLVYTLDVNEKD----FYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYD-----LTINQTLDYEQNNYFEINIEINDMK-----NFTAIMKIFIFVENVNEP 2112 E + PL + + + + A D P S I + ++ ++ P N+ V E GS++G + VD+ + + V D F VD +++ LDYE + + + +E D + S + K EI+V D N+ + + + + + EN + G I D D + S + + L + LT IR Q + + + R + ++ V D N+N S S I V +IL+V + D N S ++ N+ +SL G LS A+D + E+++ I+ AE ++ + Q+L +Q+IDVN EAP + + V EN G+ + K + D + S IT+ + F+I+ + LD E Y L + D G + +E+ D N+ + ++PEN+P + + + A D D L Y + + D + L + D E +P Y + + D G P L+ + T ++++L+ N+N + K+ Y ++EN E + + V D D+ +N +I+ FL Q E F D +T LD E+ + + D+ N +A +K+ I N N P Sbjct: 1258 TGELKTASPLRWAERAE-YTFTLTAADHGTPGLSSTCQIRIQVISSSRSIPKPNVLSMTLNVVEGTAPGSIIGSVGQVDKPESNVLEGQVTYLVVDGTDRDGTFMVDRLRGDVYLVRELDYEKGSSYTLHVEVSDFSKAFPNSYLVKLEINVQDSNDHAPQF----SEDPVTIVIPENKEPGASIYAFQAGDQDGSGPNSELRYSIEHQWPQTSDLLALDPLSGVLT-IRQQLDRESTPFLYLVVRATDQAVDLSQRRWGSVTARLFVKDENDNPPVFSSPSAISVMEDQPVGFVILHVMAHDADEGENGRVSYRIQSGNNAGRFSLSPNTGSLSILKALDREEQEVFNLTIV--------------------AE--------DHGIPQLSTSQVLC------VQVIDVNDEAPMFQQAEFGTHVMENKGPGTTVLKVTATDRDQGSNGH------ITYGGVTEDGFVINPLTGVITTTKELDAELQNHYVLTVYARDGGLPPNFAKAVVRVEVQDVNDNAPVFAKMWYGLEVPENQP-AVELCFVKATDPDSGPGGELEYKIAAGDPDGDFQLHSRTGALSTSHGLDREKKPKYTLEVVAVDRGSPALSATATVEVKVLDVNDNSPVFSKNSY-----TVEVLEN--AEEGYQVLQVSATDVDEGLNGKIL----YFLSQ---EADGAFAVDEDTGRITTAAPLDREKLASYNFRVFAVDLSPSVPINSSAQVKVTILDVNDNAP 1942 HSP 4 Score: 56.9954 bits (136), Expect = 2.665e-7 Identity = 70/299 (23.41%), Postives = 125/299 (41.81%), Query Frame = 1 Query: 1072 LNYESSYVNYFVVGAY--KDQILIFNKTYFIQLIDVNEAPQGLTL------YPSTVTENIPSGSVIGKFSILD------SNLNSTIEKC--SLQLITFNEI-FLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPE--NLSLSNNQIPENEPIGLLIAIINAQDNDK--NSTLVYTLDVNEKDFYIE--NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEII--------IKDQYGNKTEVFHIMENNELEMTFATIT 1875 L+YE V+ VV A Q + N I + D N+ +T+ ++E G + + S+ D +N+N ++E L T + I +LI Q+ LD E+ +Y+L + TD G + + ++++D N+ P + IPE G + + A+D D+ N + Y+L +K F I+ + + T D E+ P +T+ D G P L+ + DI + + N+N + +K+ T + +E +F TIT Sbjct: 303 LDYELKRVHELVVQARDNASQPEVTNAFVTIHVRDFNDNQPTMTIIFLSEDGSPRISEGAQPGQYVARISVTDPDYGEYANVNVSLEGGDGKFALTTKDSIIYLIYVDQV-------LDREERDSYDLRVMATDSGTPPLRAESSFTIQVTDVNDNPPLFDQQAYRQTIPEVVYPGSFVLQVTARDKDQGPNGDVRYSLLKGKKWFSIDPITGIITTATALDFESEPAPSVTVIATDGGRPPLSSTAKVDIVVQDVNDNAPVFSSNFYNVSVKENTPAGTCFLEVSATDEDRGSFGTIT 594
BLAST of Protocadherin Fat 4 vs. Ensembl Medaka
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:101162450]) HSP 1 Score: 99.7525 bits (247), Expect = 2.863e-20 Identity = 69/200 (34.50%), Postives = 95/200 (47.50%), Query Frame = 1 Query: 5065 ADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 A + F T R P+ K L +CH + SN C+ A C +N LN C C GFVG G+ +++DEC N C +C++ FQC CG +G CE+ +N CL C + C D + +C+C+ G+ G C IDDC +PC GVC D +NGF C CQ F+G C+ D Sbjct: 143 ATAVCFNGATCHDRVASFFCECPVGKTGL--------LCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVG-GACNQDMDECSIGANPCE-HFGKCVNTEGSFQCQCGRGYAGPRCEI-DINECLSMPCQNDATCLDRIGEFTCICMPGYTGTYCQTDIDDCESNPCVNDGVCRDTVNGFTCTCQPGFSGTMCQID 331 HSP 2 Score: 90.1225 bits (222), Expect = 2.433e-17 Identity = 58/152 (38.16%), Postives = 76/152 (50.00%), Query Frame = 1 Query: 5239 DEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVCLN 5682 + + C C PGF G + EIDEC + C + C+D N F CLC C +V+ C S CVHG CR+D C C GW G +C+ +DC+ PC G C D LNGF C C+Q F G C+ + C N N G C++ Sbjct: 463 NRYDCVCKPGFTGPKCN-VEIDECASSPCR-NGGTCVDEENGFHCLCPEGFKPPYC-YSQVDECGSSPCVHGSCREDINGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQGFIGNLCQVNINECASNPCLNKGTCVD 611 HSP 3 Score: 88.1965 bits (217), Expect = 1.069e-16 Identity = 56/138 (40.58%), Postives = 74/138 (53.62%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTC-EVLKVNLCLKSDCV-HGICRDDN-----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 F C C GF+GN C+ I+EC N CL + C+D V F C+C SG TC EVL C + C H +C C C GW+G CN +++CI +PC RG C + L GF+C+C+ FTG+ CE D Sbjct: 578 FTCKCRQGFIGN--LCQVNINECASNPCL-NKGTCVDGVASFTCVCELPYSGPTCAEVLTP--CSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECISNPCKNRGTCTNTLGGFVCSCRAGFTGLTCETD 710 HSP 4 Score: 84.7297 bits (208), Expect = 1.009e-15 Identity = 56/172 (32.56%), Postives = 85/172 (49.42%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 SN C + C+ + + F C C PGF +G+ C+ +IDEC C + ++C D N F+C C G CE +N C C HG C D +C C G+ G C +++C +PC G C D +N +IC CQ +G CE + C + ++G+C + N+ Sbjct: 299 SNPCVNDGVCR--DTVNGFTCTCQPGF--SGTMCQIDIDECASTPCQ-NGAKCHDRPNGFECRCAEGYEGTLCES-NINNCQPDPCHHGTCIDGIASYTCNCDPGYTGYRCENQLNECHSNPCQNSGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINR 464 HSP 5 Score: 82.8037 bits (203), Expect = 3.810e-15 Identity = 56/173 (32.37%), Postives = 85/173 (49.13%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C +N C C + E FQC C G+ G CE +I+ECL C D++ C+D + +F C+C +G C+ ++ C + CV+ G+CRD +C C G+ G C ID+C PC C D NGF C C + + G CE + +C+ + G C++ Sbjct: 219 CSIGANPCEHFGKCVNTE--GSFQCQCGRGYAG--PRCEIDINECLSMPCQNDAT-CLDRIGEFTCICMPGYTGTYCQT-DIDDCESNPCVNDGVCRDTVNGFTCTCQPGFSGTMCQIDIDECASTPCQNGAKCHDRPNGFECRCAEGYEGTLCESNINNCQPDPCHHGTCID 385 HSP 6 Score: 79.337 bits (194), Expect = 4.746e-14 Identity = 57/153 (37.25%), Postives = 78/153 (50.98%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 SN C TC +N L F C C GF G +CE +I++C+ N CL S C D VN + C C +G C L++N C + C +G C D +C C G+ GI C +I DC C G C D +NG+ C C+ FTG C+++ Sbjct: 678 SNPCKNRGTC-TNTLGG-FVCSCRAGFTG--LTCETDINDCVPNPCLSGGS-CTDGVNSYHCSCLPGFTGSRC-ALEINECQSNPCKNGGTCTDYVNSYTCTCRPGFTGIHCEINIPDCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYE 824 HSP 7 Score: 76.2554 bits (186), Expect = 4.633e-13 Identity = 53/154 (34.42%), Postives = 78/154 (50.65%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDD-NS--CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 + N C +A C +QC C PG+ G C +++EC+ N C + C + + F C C + +G TCE +N C+ + C+ G C D NS C CL G+ G C I++C +PC G C D +N + C C+ FTGI CE + Sbjct: 637 SPNPCANHAVCTHTADYLGYQCNCQPGW--QGQLCNIDVNECISNPCK-NRGTCTNTLGGFVCSCRAGFTGLTCET-DINDCVPNPCLSGGSCTDGVNSYHCSCLPGFTGSRCALEINECQSNPCKNGGTCTDYVNSYTCTCRPGFTGIHCEIN 786 HSP 8 Score: 75.8702 bits (185), Expect = 5.082e-13 Identity = 55/153 (35.95%), Postives = 75/153 (49.02%), Query Frame = 1 Query: 5239 DEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS--ENFGVC 5676 + + C C PGF G S C EI+EC N C + C D VN + C C +G CE+ + C +S C +G C D SC C SG+ G C +++C PC GVC+D L F C C + +TG C+ C+ S +N G C Sbjct: 730 NSYHCSCLPGFTG--SRCALEINECQSNPCK-NGGTCTDYVNSYTCTCRPGFTGIHCEI-NIPDCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYTGNRCQTPVDWCRRSSPCQNGGRC 878 HSP 9 Score: 74.7146 bits (182), Expect = 1.382e-12 Identity = 50/154 (32.47%), Postives = 82/154 (53.25%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCL-KSDCVH--GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 ++C TC+ + ++C C PGF G+ +CE+ +D+C + C+ + C+D VN + C C + +G+ C VN CL + + H G C + ++C+C++GW G DC+++IDDC C C D + F C C TG+ C D Sbjct: 28 SQCLNGGTCRQTS-DHSYECACLPGFEGH--NCEKNVDDCPGHKCM-NGGLCVDGVNTYNCQCPPEWTGQYC-AEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLD 176 HSP 10 Score: 71.2478 bits (173), Expect = 1.293e-11 Identity = 46/118 (38.98%), Postives = 61/118 (51.69%), Query Frame = 1 Query: 5353 LVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD--DNS--CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC---KNCSENFGVCLN 5682 + F+C C SGR CEV + C S C++G CR D+S C CL G+EG +C K++DDC G C G+C D +N + C C +TG +C D C N N G C N Sbjct: 1 MKGSFRCQCQPGYSGRICEVPTL-PCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNGGLCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFN 117 HSP 11 Score: 62.003 bits (149), Expect = 7.822e-9 Identity = 60/173 (34.68%), Postives = 82/173 (47.40%), Query Frame = 1 Query: 5197 KCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSS-RCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDNS------CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS----ENFGVC 5676 KC N TC + ++C C PGF G CE +I+ECL N C +S CI L ND+QC+C +GR C+ K ++C C + G C +S C C G+ G +C +S+ C C G C G C+C + G C+ H S + CS N GVC Sbjct: 1041 KCLNNGTCV--DRVGGYRCNCPPGFTGE--RCEGDINECLSNPCSPSNSFDCIQLPNDYQCVCKPGFTGRRCQN-KFSVCESQPCQNGGACSVSSSSPLGYTCTCQLGYIGPNCERSM-SCRELSCYNGGSCTLTSRGARCSCLPGYGGPQCQ--HRSTEGCSSKPCRNGGVC 1205 HSP 12 Score: 59.3066 bits (142), Expect = 6.080e-8 Identity = 51/163 (31.29%), Postives = 74/163 (45.40%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS------CLCLSGWEGIDCNKSIDDC-IG-DPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 ++ C N CH TC N + C C G+ G+ S E ID+C C + + C D V F C C ++G C + + C+ + C G D N C C +G+ G CN+ +D+C IG +PC G C + F C C + + G CE D Sbjct: 99 VNECLMQPNACHNGGTC-FNTIGGH-TCVCVNGWTGDDCS-ENIDDCATAVCF-NGATCHDRVASFFCECPVGKTGLLCHL--DDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYAGPRCEID 255 HSP 13 Score: 57.7658 bits (138), Expect = 1.753e-7 Identity = 47/169 (27.81%), Postives = 73/169 (43.20%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGN-----GSSCE--------EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICR---DDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 S+ C C+ N+ + F C C G+ G+ SCE + DE + C++ N C C +D +G CE +V+ C C +G CR C C+ G+ G +C + I++C PC G C D + +IC+C G+ CE + C Sbjct: 869 SSPCQNGGRCRQNDAS--FTCECKNGWSGHYCDIPRVSCETAARQRGIQTDELCHH-----GGHCVNTGNTHFCKCPADYTGSYCES-QVDHCEDKPCRNGATCRPYVGGYQCDCMPGFMGQNCEREINECQSHPCQNGGTCIDLVGHYICSCPPGTLGVLCEINEDDC 1029 HSP 14 Score: 53.1434 bits (126), Expect = 4.570e-6 Identity = 48/190 (25.26%), Postives = 77/190 (40.53%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD--------------NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNL 5685 S C + N+C+ D F+C C G+ GN C+ +D C + + RC F C C + SG C++ +V+ C + GI D+ + C C + + G C +D C PC C + G+ C+C F G CE + C++ +N G C++L Sbjct: 819 SHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYTGN--RCQTPVDWCRRSSPCQNGGRCRQNDASFTCECKNGWSGHYCDIPRVS-CETAARQRGIQTDELCHHGGHCVNTGNTHFCKCPADYTGSYCESQVDHCEDKPCRNGATCRPYVGGYQCDCMPGFMGQNCEREINECQSHPCQNGGTCIDL 1005 HSP 15 Score: 52.7582 bits (125), Expect = 6.342e-6 Identity = 48/153 (31.37%), Postives = 61/153 (39.87%), Query Frame = 1 Query: 5182 HFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDP-CNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 H C ATC+ +QC C PGF+G +CE EI+EC + C + CIDLV + C C G CE+ +D DCN + P C G C D + G+ CNC FTG CE D Sbjct: 952 HCEDKPCRNGATCRP--YVGGYQCDCMPGFMGQ--NCEREINECQSHPCQ-NGGTCIDLVGHYICSCPPGTLGVLCEI----------------NED------------DCNTPVRPRNAPPKCLNNGTCVDRVGGYRCNCPPGFTGERCEGD 1071
BLAST of Protocadherin Fat 4 vs. Ensembl Medaka
Match: notch3 (neurogenic locus notch homolog protein 2 [Source:NCBI gene;Acc:101162450]) HSP 1 Score: 99.7525 bits (247), Expect = 3.046e-20 Identity = 69/200 (34.50%), Postives = 95/200 (47.50%), Query Frame = 1 Query: 5065 ADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFN----SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLF--NFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 A + F T R P+ K L +CH + SN C+ A C +N LN C C GFVG G+ +++DEC N C +C++ FQC CG +G CE+ +N CL C + C D + +C+C+ G+ G C IDDC +PC GVC D +NGF C CQ F+G C+ D Sbjct: 266 ATAVCFNGATCHDRVASFFCECPVGKTGL--------LCHLDDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVG-GACNQDMDECSIGANPCE-HFGKCVNTEGSFQCQCGRGYAGPRCEI-DINECLSMPCQNDATCLDRIGEFTCICMPGYTGTYCQTDIDDCESNPCVNDGVCRDTVNGFTCTCQPGFSGTMCQID 454 HSP 2 Score: 90.5077 bits (223), Expect = 2.279e-17 Identity = 58/152 (38.16%), Postives = 76/152 (50.00%), Query Frame = 1 Query: 5239 DEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVCLN 5682 + + C C PGF G + EIDEC + C + C+D N F CLC C +V+ C S CVHG CR+D C C GW G +C+ +DC+ PC G C D LNGF C C+Q F G C+ + C N N G C++ Sbjct: 586 NRYDCVCKPGFTGPKCN-VEIDECASSPCR-NGGTCVDEENGFHCLCPEGFKPPYC-YSQVDECGSSPCVHGSCREDINGYRCDCEPGWVGKNCDLDRNDCLPSPCQNAGTCIDKLNGFTCKCRQGFIGNLCQVNINECASNPCLNKGTCVD 734 HSP 3 Score: 88.5817 bits (218), Expect = 8.530e-17 Identity = 59/157 (37.58%), Postives = 81/157 (51.59%), Query Frame = 1 Query: 5236 NDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD--DNS--CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC---KNCSENFGVCLN 5682 ND++ C C PGF G +I+EC ++ CI++ F+C C SGR CEV + C S C++G CR D+S C CL G+EG +C K++DDC G C G+C D +N + C C +TG +C D C N N G C N Sbjct: 86 NDQYNCSCPPGFQGKNCH-NDINECRKPGVCLNNGLCINMKGSFRCQCQPGYSGRICEVPTL-PCAPSQCLNGGTCRQTSDHSYECACLPGFEGHNCEKNVDDCPGHKCMNGGLCVDGVNTYNCQCPPEWTGQYCAEDVNECLMQPNACHNGGTCFN 240 HSP 4 Score: 88.1965 bits (217), Expect = 1.052e-16 Identity = 56/138 (40.58%), Postives = 74/138 (53.62%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTC-EVLKVNLCLKSDCV-HGICRDDN-----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 F C C GF+GN C+ I+EC N CL + C+D V F C+C SG TC EVL C + C H +C C C GW+G CN +++CI +PC RG C + L GF+C+C+ FTG+ CE D Sbjct: 701 FTCKCRQGFIGN--LCQVNINECASNPCL-NKGTCVDGVASFTCVCELPYSGPTCAEVLTP--CSPNPCANHAVCTHTADYLGYQCNCQPGWQGQLCNIDVNECISNPCKNRGTCTNTLGGFVCSCRAGFTGLTCETD 833 HSP 5 Score: 84.7297 bits (208), Expect = 1.062e-15 Identity = 56/172 (32.56%), Postives = 85/172 (49.42%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNK 5694 SN C + C+ + + F C C PGF +G+ C+ +IDEC C + ++C D N F+C C G CE +N C C HG C D +C C G+ G C +++C +PC G C D +N +IC CQ +G CE + C + ++G+C + N+ Sbjct: 422 SNPCVNDGVCR--DTVNGFTCTCQPGF--SGTMCQIDIDECASTPCQ-NGAKCHDRPNGFECRCAEGYEGTLCES-NINNCQPDPCHHGTCIDGIASYTCNCDPGYTGYRCENQLNECHSNPCQNSGKCVDLVNKYICQCQHGTSGTNCEINFDDCASNPCDYGICKDGINR 587 HSP 6 Score: 82.8037 bits (203), Expect = 4.217e-15 Identity = 56/173 (32.37%), Postives = 85/173 (49.13%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 C +N C C + E FQC C G+ G CE +I+ECL C D++ C+D + +F C+C +G C+ ++ C + CV+ G+CRD +C C G+ G C ID+C PC C D NGF C C + + G CE + +C+ + G C++ Sbjct: 342 CSIGANPCEHFGKCVNTE--GSFQCQCGRGYAG--PRCEIDINECLSMPCQNDAT-CLDRIGEFTCICMPGYTGTYCQT-DIDDCESNPCVNDGVCRDTVNGFTCTCQPGFSGTMCQIDIDECASTPCQNGAKCHDRPNGFECRCAEGYEGTLCESNINNCQPDPCHHGTCID 508 HSP 7 Score: 79.337 bits (194), Expect = 4.910e-14 Identity = 57/153 (37.25%), Postives = 78/153 (50.98%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 SN C TC +N L F C C GF G +CE +I++C+ N CL S C D VN + C C +G C L++N C + C +G C D +C C G+ GI C +I DC C G C D +NG+ C C+ FTG C+++ Sbjct: 801 SNPCKNRGTC-TNTLGG-FVCSCRAGFTG--LTCETDINDCVPNPCLSGGS-CTDGVNSYHCSCLPGFTGSRC-ALEINECQSNPCKNGGTCTDYVNSYTCTCRPGFTGIHCEINIPDCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYE 947 HSP 8 Score: 76.2554 bits (186), Expect = 4.478e-13 Identity = 53/154 (34.42%), Postives = 78/154 (50.65%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDD-NS--CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 + N C +A C +QC C PG+ G C +++EC+ N C + C + + F C C + +G TCE +N C+ + C+ G C D NS C CL G+ G C I++C +PC G C D +N + C C+ FTGI CE + Sbjct: 760 SPNPCANHAVCTHTADYLGYQCNCQPGW--QGQLCNIDVNECISNPCK-NRGTCTNTLGGFVCSCRAGFTGLTCET-DINDCVPNPCLSGGSCTDGVNSYHCSCLPGFTGSRCALEINECQSNPCKNGGTCTDYVNSYTCTCRPGFTGIHCEIN 909 HSP 9 Score: 75.8702 bits (185), Expect = 4.912e-13 Identity = 55/153 (35.95%), Postives = 75/153 (49.02%), Query Frame = 1 Query: 5239 DEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS--ENFGVC 5676 + + C C PGF G S C EI+EC N C + C D VN + C C +G CE+ + C +S C +G C D SC C SG+ G C +++C PC GVC+D L F C C + +TG C+ C+ S +N G C Sbjct: 853 NSYHCSCLPGFTG--SRCALEINECQSNPCK-NGGTCTDYVNSYTCTCRPGFTGIHCEI-NIPDCTESSCFNGGTCTDKINGYSCTCRSGFTGSHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYTGNRCQTPVDWCRRSSPCQNGGRC 1001 HSP 10 Score: 74.7146 bits (182), Expect = 1.347e-12 Identity = 50/154 (32.47%), Postives = 82/154 (53.25%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCL-KSDCVH--GICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 ++C TC+ + ++C C PGF G+ +CE+ +D+C + C+ + C+D VN + C C + +G+ C VN CL + + H G C + ++C+C++GW G DC+++IDDC C C D + F C C TG+ C D Sbjct: 151 SQCLNGGTCRQTS-DHSYECACLPGFEGH--NCEKNVDDCPGHKCM-NGGLCVDGVNTYNCQCPPEWTGQYC-AEDVNECLMQPNACHNGGTCFNTIGGHTCVCVNGWTGDDCSENIDDCATAVCFNGATCHDRVASFFCECPVGKTGLLCHLD 299 HSP 11 Score: 62.3882 bits (150), Expect = 7.739e-9 Identity = 60/173 (34.68%), Postives = 82/173 (47.40%), Query Frame = 1 Query: 5197 KCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSS-RCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDNS------CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS----ENFGVC 5676 KC N TC + ++C C PGF G CE +I+ECL N C +S CI L ND+QC+C +GR C+ K ++C C + G C +S C C G+ G +C +S+ C C G C G C+C + G C+ H S + CS N GVC Sbjct: 1164 KCLNNGTCV--DRVGGYRCNCPPGFTG--ERCEGDINECLSNPCSPSNSFDCIQLPNDYQCVCKPGFTGRRCQN-KFSVCESQPCQNGGACSVSSSSPLGYTCTCQLGYIGPNCERSM-SCRELSCYNGGSCTLTSRGARCSCLPGYGGPQCQ--HRSTEGCSSKPCRNGGVC 1328 HSP 12 Score: 59.3066 bits (142), Expect = 6.014e-8 Identity = 51/163 (31.29%), Postives = 74/163 (45.40%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNS------CLCLSGWEGIDCNKSIDDC-IG-DPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 ++ C N CH TC N + C C G+ G+ S E ID+C C + + C D V F C C ++G C + + C+ + C G D N C C +G+ G CN+ +D+C IG +PC G C + F C C + + G CE D Sbjct: 222 VNECLMQPNACHNGGTC-FNTIGGH-TCVCVNGWTGDDCS-ENIDDCATAVCF-NGATCHDRVASFFCECPVGKTGLLCHL--DDACVSNPCNEGAVCDTNPLNGRAICTCPAGFVGGACNQDMDECSIGANPCEHFGKCVNTEGSFQCQCGRGYAGPRCEID 378 HSP 13 Score: 57.7658 bits (138), Expect = 1.778e-7 Identity = 47/169 (27.81%), Postives = 73/169 (43.20%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGN-----GSSCE--------EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICR---DDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 S+ C C+ N+ + F C C G+ G+ SCE + DE + C++ N C C +D +G CE +V+ C C +G CR C C+ G+ G +C + I++C PC G C D + +IC+C G+ CE + C Sbjct: 992 SSPCQNGGRCRQNDAS--FTCECKNGWSGHYCDIPRVSCETAARQRGIQTDELCHH-----GGHCVNTGNTHFCKCPADYTGSYCES-QVDHCEDKPCRNGATCRPYVGGYQCDCMPGFMGQNCEREINECQSHPCQNGGTCIDLVGHYICSCPPGTLGVLCEINEDDC 1152 HSP 14 Score: 53.1434 bits (126), Expect = 4.187e-6 Identity = 47/189 (24.87%), Postives = 75/189 (39.68%), Query Frame = 1 Query: 5173 SICHFNSNKCHRNATCKSNELND---EFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDD--------------NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCS-ENFGVCLNL 5685 S C + N+C+ D F+C C G+ GN +D C + + RC F C C + SG C++ +V+ C + GI D+ + C C + + G C +D C PC C + G+ C+C F G CE + C++ +N G C++L Sbjct: 942 SHCQYEVNECNSQPCLNGGVCQDGLESFRCTCPKGYTGNRCQ-TPVDWCRRSSPCQNGGRCRQNDASFTCECKNGWSGHYCDIPRVS-CETAARQRGIQTDELCHHGGHCVNTGNTHFCKCPADYTGSYCESQVDHCEDKPCRNGATCRPYVGGYQCDCMPGFMGQNCEREINECQSHPCQNGGTCIDL 1128 HSP 15 Score: 52.7582 bits (125), Expect = 6.374e-6 Identity = 48/153 (31.37%), Postives = 61/153 (39.87%), Query Frame = 1 Query: 5182 HFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDP-CNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 H C ATC+ +QC C PGF+G +CE EI+EC + C + CIDLV + C C G CE+ +D DCN + P C G C D + G+ CNC FTG CE D Sbjct: 1075 HCEDKPCRNGATCRP--YVGGYQCDCMPGFMGQ--NCEREINECQSHPCQ-NGGTCIDLVGHYICSCPPGTLGVLCEI----------------NED------------DCNTPVRPRNAPPKCLNNGTCVDRVGGYRCNCPPGFTGERCEGD 1194
BLAST of Protocadherin Fat 4 vs. Ensembl Medaka
Match: ENSORLT00000012788.2 (eyes shut homolog [Source:NCBI gene;Acc:105355817]) HSP 1 Score: 98.9821 bits (245), Expect = 5.391e-20 Identity = 61/150 (40.67%), Postives = 82/150 (54.67%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 F+C C PG+ G CE ++EC+ N C ++ RCID N + CLC G CE V+ C+ + C+HG C D +CLC GW G C +IDDC+ PC RG C D ++ F C CQ +TG CE D CK+ + N +C N Sbjct: 1432 FKCVCRPGYTG--LRCEVNVNECVSNPCQ-NTGRCIDGPNQYHCLCPVGFIGLHCET-NVDECISAPCLHGSCEDGIYSYTCLCEPGWTGNRCETNIDDCVCSPCLNRGSCVDLIDKFACFCQDGYTGKTCENDVDICKDTAFNASLCFN 1577 HSP 2 Score: 87.8113 bits (216), Expect = 1.391e-16 Identity = 65/174 (37.36%), Postives = 87/174 (50.00%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDE-----FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCV-HGICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLN 5682 SN C +A C EL+ E F+C C GF +G CE +DEC N C C D+V+ F CLC +G CE ++ CL + C + C+D + C+C SGWEG DC + ID+C+ PC C D LN + C C +TG+ C D C + G CLN Sbjct: 1102 SNPCENDAVCM-EELDQERFPLGFRCLCRRGF--SGPRCEINVDECSSNPCF--HGFCYDVVDGFHCLCSPGYAGPRCEE-DIDDCLSNLCTSNSACKDLHEGYECVCHSGWEGADCQQEIDECLSQPCKNNATCTDLLNNYRCFCLPGWTGVDCAEDVRECDS-----GPCLN 1264 HSP 3 Score: 83.5741 bits (205), Expect = 2.440e-15 Identity = 58/158 (36.71%), Postives = 75/158 (47.47%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GIC---RDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQY 5703 + CFC PGF+GN CE E++ECL C S C D +N F C C +G CEV + C S C+H C D C+C G+ G C ID+C PC RG C D + C C F G CEF N EN VC+ ++ ++ Sbjct: 967 YTCFCAPGFIGN--KCEIEVNECLSLPCQNGGS-CTDELNSFSCQCPVGITGNYCEV-NIEECASSPCLHNSTCFDLVDGYKCVCQPGFTGPKCELDIDECASSPCKNRGTCVDLPGNYFCQCVAPFRGHNCEFLPCEASNPCENDAVCMEELDQERF 1120 HSP 4 Score: 79.337 bits (194), Expect = 5.105e-14 Identity = 62/177 (35.03%), Postives = 93/177 (52.54%), Query Frame = 1 Query: 5191 SNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCL-GDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLC--LKSDCVHG---ICRDDN--SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKN--CSENFGVCLNLKN 5691 S C NATC +L + ++CFC PG+ G + E++ EC CL G + D +F C C +G C+ + C L + C+HG + R + SC C +G+EG C + ++C PC +G CED +NG+ C+C+ F+G+ CE D C + CS N G C +L N Sbjct: 1221 SQPCKNNATC--TDLLNNYRCFCLPGWTGVDCA-EDVRECDSGPCLNGAQCQESDTPGEFSCACPPFFTGHLCD-QSYDPCDPLHNPCLHGSTCLTRSNGTASCRCSAGFEGSWCEINTNECASHPCQNQGHCEDQVNGYRCDCKMGFSGLHCEQDINECASSPCS-NAGTCKDLVN 1392 HSP 5 Score: 77.7962 bits (190), Expect = 1.376e-13 Identity = 47/141 (33.33%), Postives = 77/141 (54.61%), Query Frame = 1 Query: 5245 FQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCL----------CLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 + C C PG+ GN CE ID+C+ + CL S C+DL++ F C C +G+TCE V++C + +C + +CL C +G+ G C +++C PC+ VC+D +N ++C+C+ +TG+ CE D Sbjct: 1507 YTCLCEPGWTGN--RCETNIDDCVCSPCLNRGS-CVDLIDKFACFCQDGYTGKTCEN-DVDICKDTAFNASLCFNGATCLDGEGANFTCSCPAGFTGDFCEVDVNECCSAPCHNSAVCQDLINSYVCHCRSGWTGLHCEDD 1643 HSP 6 Score: 73.1738 bits (178), Expect = 3.403e-12 Identity = 53/152 (34.87%), Postives = 72/152 (47.37%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSR---CIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFD 5634 C TC N E QC C G+ G S + C+ DS C +L N ++C+C +G CE +N C+ C HG C D + C CL G G C+ +IDDC+G+PC +C+D LNG+ C C F G CE + Sbjct: 840 CKNGGTCILNSAK-ELQCICPSGYHGEDCSLSS------SRCVCDSEGTVFCNELENAYRCVCHHGHTGVHCET-PINHCVDGLCQHGSTCVDLSRGFKCDCLPGLTGRFCDVNIDDCVGEPCGALSICKDTLNGYTCFCAPGFIGNKCEIE 983 HSP 7 Score: 68.9366 bits (167), Expect = 6.435e-11 Identity = 59/182 (32.42%), Postives = 86/182 (47.25%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG--IC---RDDN--SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQYCLD 5712 NS C ATC +L +++C C GF G S +++C CL + C+D +ND+ C C G+ C L ++LC C IC RD + SC C G+ G C ++++C PC GVC D ++ + C C + F G CE H+ C +G C N N C+D Sbjct: 641 NSFPCSSGATCV--DLISDYRCLCPLGFEGRTCS-HNVNDCWSQPCL-NGGTCLDRINDYICHCPLGFKGKDCS-LDIDLCSFGLCSENTLICTETRDGHNVSCTCKKGFGGSFCEVNLNECESLPCQNGGVCVDGIDLYQCLCLEGFGGFNCEITHYKCA-----YGYCAN----NSTCID 808 HSP 8 Score: 68.1662 bits (165), Expect = 1.083e-10 Identity = 59/176 (33.52%), Postives = 86/176 (48.86%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDN---SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-KNCSENFGVCLNLKNKNQY 5703 N C +TC + N C C+ GF GS CE +EC + C + C D VN ++C C SG CE +N C S C + G C+D C+C +G+ G C+ +++C PC G+C + GF C C+ +TG+ CE + C N +N G C++ NQY Sbjct: 1302 NPCLHGSTCLTRS-NGTASCRCSAGF--EGSWCEINTNECASHPCQ-NQGHCEDQVNGYRCDCKMGFSGLHCE-QDINECASSPCSNAGTCKDLVNMFHCICPAGYFGTLCDLDVNECEVSPCLHEGICINMPGGFKCVCRPGYTGLRCEVNVNECVSNPCQNTGRCID--GPNQY 1470 HSP 9 Score: 68.1662 bits (165), Expect = 1.336e-10 Identity = 61/173 (35.26%), Postives = 83/173 (47.98%), Query Frame = 1 Query: 5200 CHRNATCKSNELNDEFQCFCNPGFVGNGSSCEE-IDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRD---DNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK--NCSENFGVCLNLKNKN 5697 C ATC +E+ D + C C G+ G CEE ID C+ + C + C+D +F C C G CEV + N C C G C D D CLC G+EG C+ +++DC PC G C D +N +IC+C F G C D C CSEN +C ++ + Sbjct: 569 CQNRATC-VDEI-DGYSCLCPSGYTG--VFCEEDIDYCVGHSC-SEHGICLDHQYNFTCRCMLGFEGPFCEV-ETNECNSFPCSSGATCVDLISDYRCLCPLGFEGRTCSHNVNDCWSQPCLNGGTCLDRINDYICHCPLGFKGKDCSLDIDLCSFGLCSENTLICTETRDGH 735 HSP 10 Score: 67.0106 bits (162), Expect = 2.446e-10 Identity = 60/196 (30.61%), Postives = 85/196 (43.37%), Query Frame = 1 Query: 5170 ISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDEC-LFNFCLGDSSRCIDLVNDFQ-----------------------------CLCGSDRSGRTCEVLKVNLCL------KSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC 5646 I I +S+ C N TC +L +++C C GF G +CE +ID C L + C+DL F+ C+C +G+TC + VN C+ ++ CV I D SCLC SG+ G+ C + ID C+G C+ G+C D F C C F G FCE + C Sbjct: 452 IEIYECDSSPCQHNGTCY--DLVGDYECQCPAGF--QGKNCEVDIDACGLPTSTCSTKTLCLDLPKGFEYSCHVPCPQDFQPCANGGHCVLNNASSYTCICTRGWTGQTCRI-NVNDCIQHWCQNRATCVDEI--DGYSCLCPSGYTGVFCEEDIDYCVGHSCSEHGICLDHQYNFTCRCMLGFEGPFCEVETNEC 640 HSP 11 Score: 67.0106 bits (162), Expect = 3.069e-10 Identity = 52/175 (29.71%), Postives = 77/175 (44.00%), Query Frame = 1 Query: 5188 NSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDEC--LFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCV-HGICRDD---NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCK-NCSENFGVCLNLKN 5691 +S C A C+ ++ EF C C P F G+ + D C L N CL S+ C C + G CE+ N C C G C D C C G+ G+ C + I++C PC+ G C+D +N F C C + G C+ D C+ + + G+C+N+ Sbjct: 1258 DSGPCLNGAQCQESDTPGEFSCACPPFFTGHLCD-QSYDPCDPLHNPCLHGSTCLTRSNGTASCRCSAGFEGSWCEI-NTNECASHPCQNQGHCEDQVNGYRCDCKMGFSGLHCEQDINECASSPCSNAGTCKDLVNMFHCICPAGYFGTLCDLDVNECEVSPCLHEGICINMPG 1430 HSP 12 Score: 65.855 bits (159), Expect = 6.589e-10 Identity = 50/142 (35.21%), Postives = 72/142 (50.70%), Query Frame = 1 Query: 5185 FNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCE-EIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDN-----SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFIC 5592 FN++ C ATC E F C C GF G+ CE +++EC C +S+ C DL+N + C C S +G CE +N CL C+ GIC ++ +C C G+ G +C + DDC+ +PC C D +N C Sbjct: 1570 FNASLCFNGATCLDGE-GANFTCSCPAGFTGD--FCEVDVNECCSAPCH-NSAVCQDLINSYVCHCRSGWTGLHCED-DINECLPQPCIQGICIQNDPGYGYTCFCRPGFVGKNCEYNYDDCLLNPCPEALSCVDGINKVSC 1706 HSP 13 Score: 56.6102 bits (135), Expect = 3.704e-7 Identity = 55/186 (29.57%), Postives = 78/186 (41.94%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEI-DECL-FNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCE------VLKVNLCL-KSDCV---HGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC----KNCSENFGVCLNLKNKNQY 5703 + C N TC S ++ C C GF +G +CEEI D C N + C+ ++ QC+CG G C+ + N CL + C+ +C CL G+ G C I +C PC G C D + + C C F G CE D +C CS +CL+L +Y Sbjct: 337 SPCLNNGTCVSR--GTDYVCRCLSGF--SGRNCEEIIDYCRQLNIICLNEGLCLSVIGGHQCVCGPGWIGELCQHVGDACAMGTNSCLNGATCITMSQPTSPPQYTCKCLPGFIGTMCEIEIYECDSSPCQHNGTCYDLVGDYECQCPAGFQGKNCEVDIDACGLPTSTCSTKT-LCLDLPKGFEY 517 HSP 14 Score: 53.9138 bits (128), Expect = 2.665e-6 Identity = 45/156 (28.85%), Postives = 63/156 (40.38%), Query Frame = 1 Query: 5194 NKCHRNATCKSNELNDE----FQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDL-VNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDD-----NSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCE 5628 N C C SN D ++C C P F G +C EI + ++ C+ + F+C+CGS SG CE K C + C G C + C+C G +C + D C PC G C ++C C F+G CE Sbjct: 214 NPCQNKGVCLSNGSTDPNKRTYKCLCPPHFTG--PNCSEIVGKANCVRVCENGTCVQMSPTSFKCICGSGFSGPPCEKTKAP-CDPNPCREGGACAESPKGFATECICADGTVVPECRRQQDACTPSPCLNNGTCVSRGTDYVCRCLSGFSGRNCE 366
BLAST of Protocadherin Fat 4 vs. Ensembl Medaka
Match: fat3a (FAT atypical cadherin 3 [Source:NCBI gene;Acc:101161322]) HSP 1 Score: 94.7449 bits (234), Expect = 1.230e-18 Identity = 262/1179 (22.22%), Postives = 489/1179 (41.48%), Query Frame = 1 Query: 109 SISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDAND-PPTNIQLSNWKV--EENILVGSLVGQISVVDEDLDDSFKCS---VKSDSPFNVDANFNL-FTKAPLDYETQARFEVIIECLDHENSS----VINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLS-EIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINE-------------LYSFQI-----LILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNE-AP-QGLTLYPSTVTENIPSG-SVIG-KFSILDSNLNSTIEKCSLQLITFNEIFLI---SQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANE-RPE-NLSLSNNQIPEN------EPIGLLIAIINAQDNDKNSTLVYTL-DVNEKDFYIENNKLLSGTVFDHENRP--GYQI-TITVFDNGDPKLNVSKTFDIEIL---NSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFV--ENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND--PPTVAGLNFTMIPSFVEKDFIIGKVNVFDED---NLSTYNQIECS------IIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLG-QLLLMTDYSNKSLQISKSSIIVLVSNNIK--IQINEDNSFML-TDPLDYETENNFLISFTLIDKNSNQS-----INLKVQILDVNEAPSEIKSFEKNLTMFEKSPP-----NIH--IATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLT-DVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQS--RFYIQIINVNDGP 3393 S+ P++ E K ++ L I DL +P+ ++ + I DAND P +Q +K+ EN+ +G+ + Q+ D+D+ + + + S +PF +++ + + A LD E +RF + IE D + + EI + D+N+ +++ + + L E+ GT + + +DPD V N K IR+ EL + ++ L + R + LS V++ +++V+EN V+ E +L ++SA D+D L F I +I TD ++ + K+ W+ A + V F F+Q+ D+N+ AP LY +V EN P SVI + D++ ++++ S Q+++ N L + +LD E + L + ++D G + +I+++ D N+ +P + + ++PE EPI + A D NS + Y++ D NE ++ + K +GTV P GY I TI DNG P+ + + IE + ++ P ++ + + N F +MEN+++ +++ + + + NS F V+K + I I + LD EQ +++ + + D + TA ++ I V N N+P I + + I+E+ + + +D D+++ + YS+ + ++ N F + + +Q D+E+ + VL++ D V I ++D ND P + L + K + +V D+D N IE I+P+ I++++ NL++ T ++ + ++ +NG + ST +A+ +N F ++ TE S N +G + ++ +S +L I + N + QIN+ + + LDYET S+TLI + N + L +QILD N+ P ++ E +P N+H ATDPD+N Q ++ EI ++ K+ + T + ++ + F + RD G+P L+ S IQ+I+ ND P Sbjct: 784 SVFLPMDRE-KRDHYLLNITIYDLGIPQKMAWRLLSIHIEDANDNAPQFLQEDGYKITIPENMAIGTDIIQVEATDKDMGPNGEVMYSILTSTTPFGINSTTGMVYVAAQLDRELTSRFTLKIEARDRADKESPKFSVTTLEIILEDVNDC-SPLFIPSVFKARAL---EDLPVGTVVAWLETHDPDLG-------LGGQVRFSLVNDHNGWFELDKASGAIRLTKELDYETQQFYNLTVKAKDKGRPVSLLSVTFVELEVIDVNENLYAPYFTHFALTGVVKENARIGTTLLQVSANDDDTGRDGEIHYSIRDGSGLGRFSIDEETGVIYTTDILDRETKDSYWLTVYAS---DRGVVPQFT-----------TIDVFVQVEDINDNAPLTSEPLYRPSVPENSPPDVSVIQIQAQDPDTSPSTSLHWLSYQIVSGNPQHFFNMDPHSGLITTTSHKLDRELQTEHVLEVVISDGGPNPRQSTVLVIVQVLDENDNKPTFHEKVYKVKLPERERRKKAEPIYRVFAY--DLDEGPNSDISYSIVDGNEDGKFVIDPK--TGTVQSRRAFPAGGYDILTIKATDNGRPQKSSTARLHIEWIPQPPASTQP-LVFSESFYN----FTVMENDKVAEIVGVVSLQWSSAPVWFDIRGGNSNSVFDVEKA--VGTIL-----IAKPLDAEQRSFYNLTVLATDGTH-TAYTQVHILVLDNNDNDP-----IFSQQAYEVTISEDTPTDTEVLQIVASDRDEHNELTYSLQSSIDPNSMRLFRIHPTLGTIFTTQRLDHEACAQHILTVLVKDQDFPYRKNLARVLIEVEDINDHVPIFTSPLYEGSVYESAAKGSAVVQVTALDKDKGKNAELRYSIEAGNTGNTFRIEPV--LGIISVAHNLDL-TNVGHYV------VTVRVTDNGVPPL-STNTVVRIAVTLSDNTGPKFP---QPEYQTEVSENALIGTSITTVSAFSQSTL------IYDIKQGNAEHVFQINQYSGVITNQKALDYETTE----SYTLIVQAVNMAGMASNATLLIQILDENDNPPVFLQHHYYGSISEVAPVKSVVLNLHGLPLVIRATDPDHN-------QNALLVYEIVENTAKKVFTVDSGTGSIRTIANLDHETFPIFIFHVQVRDSGRPQLTADSPTEVTIQVIDSNDSP 1884 HSP 2 Score: 72.7886 bits (177), Expect = 5.288e-12 Identity = 142/584 (24.32%), Postives = 250/584 (42.81%), Query Frame = 1 Query: 1198 LYPSTVTENIPSGSVIGKFSILDSNLNSTIE-KCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSN--NQIPENEPIGLLIAIINAQDNDK--NSTLVYTL-DVNEKDFYIENNKLLSGTV-----FDHENRPGYQITITVFDNGDP-KLNVSKTFDIEILNSNENPEII-IKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQII------SDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIIN-ITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKF-EFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSG--GLSIDLEVPISIQDAND-PPTVAGLNFTMIPSFVEKDFIIG----KVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIV------TTATRFIDEKFID---IEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQL 2826 +Y +++ E++P S++ D+++ + + SL + ++ F I E+K LD+EKTP+Y L ++ D G + EI L ++D N+ P ++ + EN L+ I A D D+ +VY+L D F I++ +SG V D E + YQIT+ D G P L I +L+ N+N I +DQ E ++ + + V+ D N +I +++ RF V S + + Q LDYE + + +E D +A+ + I + +VN+ SR++ ++E+ + + + D D N + YS+++ ++ F + NG +K ++ D E+ + IRA+DSG +S V I + D ND PPT + N T + ++++ IG +++V D D S+ N P F IL+ ++ E V TA + +F I+IQ ++G + S+T T IE+ N P V + + +GQL Sbjct: 3046 MYTASIPEDLPVHSLLLTVGATDADVGVNAQIQYSLHG-SGSQDFSIDPDTGEVKSLVTLDHEKTPSYRLVVQAMDGGGQ--WCSAEIQLVVTDVNDNPPIFTMPQYTANVYENTIPKALLTRIQAIDPDEGPGRMVVYSLTDSAGGLFSIDH---VSGVVILEHTLDREVQSTYQITVCASDQGSPLPLYSLVNVTITVLDINDNHPIFEHRDQLTTVPE--------DVRVGTEVLRVYAASKDIGTNAEITYTIRSGNEHRRFHVHPHSGA-------IIVAQPLDYETCRDYFLTVEARDGGTPPLSAVTTVNINLTDVNDNAPMF----SRDLYTAFVSEDAFIGEFVVQLVAEDSDSHLNGAVLYSVVSGDQGSQFFIDPING----VIKVNKPLDRETI--PSFSLTIRALDSGVPPMSSTALVNIDVSDVNDNPPTFSSANLTAV---IQENKPIGTTILQLSVIDRD--SSRN-------GPPFSFQILSGNEGREFVLKEDGTLTANQVFKREFATEYIIQIQVSDSGKPSLSSSTMLTVAVIEESLNRPVALPLEIHVVTMEDEFPGGVIGQL 3586 HSP 3 Score: 68.5514 bits (166), Expect = 9.482e-11 Identity = 100/407 (24.57%), Postives = 180/407 (44.23%), Query Frame = 1 Query: 1372 LDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERP---ENLSLSNNQIPENEPIG--LLIAIINAQDNDKNSTLVYT----LDVNEKDFYIENNK--LLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSR--FLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND-MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDV--IKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDAND--PPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLS 2538 LDYE T +Y+L +R TDY + ++ + I D N+ P + +S S + + E IG +L I + QD++KN+ + Y L + F+I+++ +L+ + DHE Y + DNG P L+ T + + + N+N + +Q + V + DF DK+ I+S N R F+++K + I L ++ + + + +N+ ++D + TA + I + N++ P + ++ + + EN ++ TD DQ I YS N + ++ SNG Y+ + D E +DI +++ A D GG V I++ D ND P VA + V K F++ ++ D D+ S Sbjct: 2250 LDYEVTSSYHLTVRATDY-LTGAHAEVDLGVFIQDINDNPPIFQKMSYSVS-LSETAMIGTPVLQVIASDQDSEKNNIIRYQIFSQLHNSTDYFHIDSSSGLILTARMLDHELAHNYYFVVRATDNGYPALSSEVTVTVTLNDMNDNAPVF--NQLLYEAYVSELAPRGHFITCVQASDADSSDF-DKLEYSILSGNERMHFVLEKSTGI-------LALSSHRKQKMDPTYSLNVSVSDGVFTSTAQVHIKVLGANLHSPVFERSVYEAE-----LRENAAVGTTVIQVKATDKDQEPFGHITYSFANDVGSDQFSIDSNG----YICTVEKLDREDPANRDILLIVAAQDLGGRVSYCTVQITLLDDNDNSPSFVATEYQASLKHDVTKGFLVTQLQAHDLDDGS 2635 HSP 4 Score: 63.929 bits (154), Expect = 2.318e-9 Identity = 45/143 (31.47%), Postives = 64/143 (44.76%), Query Frame = 1 Query: 5344 CIDLV--NDFQCLCGSDRS--GRTCEV--LKVNLCLKSD-CVHGICRDDN----------SCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSC-----KNCSENFGVCLNLKNKNQYC 5706 C+DLV ND + S RS E+ LK+ L D C+H C + SC C + G +C C+ +PC GVC+ N F+C+C++ F G+ CE D C + EN G C+N + YC Sbjct: 4004 CLDLVTLNDNELPLQSKRSLYAEVVELTELKLGCVLYPDPCLHQPCHNGATCNSLPSGGFSCSCSHQFTGGNCEMKKTVCVPNPCQNSGVCKPIGNAFLCSCRRGFRGLVCEEDVNECDRNNPEGECENGGTCVNTPG-SFYC 4145 HSP 5 Score: 56.6102 bits (135), Expect = 4.105e-7 Identity = 34/119 (28.57%), Postives = 54/119 (45.38%), Query Frame = 1 Query: 5302 DECLFNFCLGDSSRCIDLVND-FQCLCGSDRSGRTCEVLKVNLCLKSDCVH-GICRDDNS---CLCLSGWEGIDCNKSIDDC-IGDP---CNGRGVCEDALNGFICNCQQNFTGIFCEF 5631 D CL C + + C L + F C C +G CE +K +C+ + C + G+C+ + C C G+ G+ C + +++C +P C G C + F CNC F G C Sbjct: 4042 DPCLHQPC-HNGATCNSLPSGGFSCSCSHQFTGGNCE-MKKTVCVPNPCQNSGVCKPIGNAFLCSCRRGFRGLVCEEDVNECDRNNPEGECENGGTCVNTPGSFYCNCTPGFVGQRCSL 4158 HSP 6 Score: 52.373 bits (124), Expect = 6.878e-6 Identity = 170/809 (21.01%), Postives = 317/809 (39.18%), Query Frame = 1 Query: 1201 YPSTVTENIPSGSVIG--KFSILD--SNLNSTIEKCSLQLITFNE--IFLISQFQLELKDNTRLDYEKTPAYNLGIRVT-DYGQENIVTDFEIILEISDANE-RPENLSLSN-NQIPENEPIGLLIAIINAQDND--KNSTLVYTLD--VNEKD--------FYIENNKLLSGTVF-----DHENRPGYQITITVFDNGDPKLNVSKTFDIEIL-NSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPD---FDDKINCQIISDNSR-----FLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFV--ENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQ--NDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDF-------IIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQIN---EDNSFMLTDPLDYETENNFLISFTLIDKNS---NQSINLKVQILDVNE-APSEIKSFEKNL-TMFEKSPPNIH--IATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVL 3459 Y + EN P GSVIG + SI S+L +T + + N +FL+ + +K + LD+E + + T + + +T + + + D N+ RP + S + E +G + + A D D N + Y L + K F I++N SG +F DHE P Y T+ D+G+ S T + + N+N + + Y + + E++ A + + D + I+ I N R LVQ ++ + + LD E+ N++ INI D F + K+ + V N N P + +I E++ + + TD D N I+YS L+ + +FS +K D+E +++++A+D GG E+ + + D ND P + FTM P + + ++ ++ D D + FSI ++S + + T R + + I + + G + + + + DIN+ F D +T ++ +G +L ++K + + + S N + + + ++ PLDYET ++ ++ D + + + + + DVN+ AP F ++L T F I + A D D + + + +V+G+ + + +N + + LD I F + I D G P +S + I + +VND P + I+E+ I T + Sbjct: 2717 YSFNIPENTPIGSVIGTVRVSIPPEYSSLTATFATANGESGENNREMVFLVEKDTGVIKLDKALDHEAIKEFYFKVTATVKQAKLDSMTSANVKVNVFDINDNRPAFETNSYVATVMEGTAVGTKVIRVQASDPDSGANGQVTYRLGSLIKSKGNSEPLSDIFNIDSN---SGWIFIRTDLDHETSPFYTFTVVALDHGEVLSLSSTTTVTVTVSDVNDNAPVFTETHY-----IGTVRESDPPGEVVAVLNTRDEDSSVVNQHISIHITGGNDRGVFALRLVQG--------EWKMYVKGPLDREKRNFYLINITATDGL-FVSQTKVEVTVMDANDNSPDCDQVM-----YTASIPEDLPVHSLLLTVGATDADVGVNAQIQYS----LHGSGSQDFSIDPDTGEVKSLVTLDHEKT--PSYRLVVQAMDGGGQWCSAEIQLVVTDVNDNPPI----FTM-PQYTANVYENTIPKALLTRIQAIDPDEGPGRMVVYSLTDSAGGLFSIDHVSGVVILEHTLDREVQSTY-QITVCASDQGSPLPLYSLVNVTITVLDINDNHPIFEHR---DQLTTVPEDVRVGTEVLRVYAASKDIGTNAEITYTIRSGNEHRRFHVHPHSGAIIVAQPLDYETCRDYFLTVEARDGGTPPLSAVTTVNINLTDVNDNAPM----FSRDLYTAFVSEDAFIGEFVVQLVAEDSDSHL--NGAVLYSVVSGDQGSQFFIDPINGVIKVN-KPLD---RETIPSFSLTIRALDSGVPPMSSTALVNIDVSDVNDNPPTFSSANLTAVIQENKPIGTTI 3478
BLAST of Protocadherin Fat 4 vs. Planmine SMEST
Match: SMESG000032466.1 (SMESG000032466.1) HSP 1 Score: 3576.18 bits (9272), Expect = 0.000e+0 Identity = 1848/1848 (100.00%), Postives = 1848/1848 (100.00%), Query Frame = 1 Query: 565 MILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAXXXXXXXXXXXXEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMIQYPANKYFYIINCCDLMTQNLEYAWTGPLNASFIITDNGIPPMKSIFNISFNFIESKGEISATNRLINITDKANTLIGILKYSLSNSDDISFILEEVPDNAFSIIKDELWLTKDADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQYCLDXXXXXXXXXXXXXXLINQFSTYKIDFFKFISNIIEFENFTIYFNILNFDLINYRMDFSLIDNDGNVYPPEQSWDIVKQNCNFTDSLSSPAIICSELFPPVDNPKKRAENLKSQFLTYCLIFAIYWGCDGLIF 6108 MILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVSCQNSQCLNLNLNYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAIFEIEDEDTDDIHQCHGSNSYFGISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAISSISKDLSIKLEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMIQYPANKYFYIINCCDLMTQNLEYAWTGPLNASFIITDNGIPPMKSIFNISFNFIESKGEISATNRLINITDKANTLIGILKYSLSNSDDISFILEEVPDNAFSIIKDELWLTKDADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQYCLDSSNISNKNFNFSENLINQFSTYKIDFFKFISNIIEFENFTIYFNILNFDLINYRMDFSLIDNDGNVYPPEQSWDIVKQNCNFTDSLSSPAIICSELFPPVDNPKKRAENLKSQFLTYCLIFAIYWGCDGLIF Sbjct: 1 MILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVSCQNSQCLNLNLNYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAIFEIEDEDTDDIHQCHGSNSYFGISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAISSISKDLSIKLEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMIQYPANKYFYIINCCDLMTQNLEYAWTGPLNASFIITDNGIPPMKSIFNISFNFIESKGEISATNRLINITDKANTLIGILKYSLSNSDDISFILEEVPDNAFSIIKDELWLTKDADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQYCLDSSNISNKNFNFSENLINQFSTYKIDFFKFISNIIEFENFTIYFNILNFDLINYRMDFSLIDNDGNVYPPEQSWDIVKQNCNFTDSLSSPAIICSELFPPVDNPKKRAENLKSQFLTYCLIFAIYWGCDGLIF 1848 HSP 2 Score: 96.2857 bits (238), Expect = 2.408e-19 Identity = 259/1064 (24.34%), Postives = 438/1064 (41.17%), Query Frame = 1 Query: 115 SCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSF-KCSVKSDSPFN---VDANFNLFTK--APLDYETQARFEVIIECLDHENSSVINKHEI--SVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN----SLSEIVKIIILNVDENPTDLKLNDSTSNKV----LIEENSSNYSLGELSAIDEDINELYSFQIL-----ILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY--FIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSIL-----DSNLNSTIEKCSLQLITFNEIFLISQF--QLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNST---LVYTLDVNEKDFYIEN---NKLLSGTVFDHENRPGYQITITVFDNGDPKLN---VSKTFDIEILNSNE-----NPEIIIKDQYGNKTEVFHIM-----ENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKF----------EFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIE--IQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIK--IQINEDNSFMLTDPLDYETENNFL-ISFTLID-KNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSP 3111 S LN+ES N + KD + N FI ++D N+ P + L V ENI GS++G+ S++D +L+ + KCS++ + FN + + F L K LDYE + + I D+ +++ EI ++D NE P+ + + +N ++ EN G I +I D D+ NST V + + + K L+ G F+ ++ +QI++T +N ++S+ I ILN +ENP ++ + D NK ++E N + ++ + D ++ + QI+ L EIK+ + + + L+YE + NYF + + + F FI + +VNE P L + S + ++ G SI D + N I+ L + NE F S +L LK++ DYE ++ + + + D E+ + I DAN+ P L+ IP +I +N D D ST + ++ K F I N N + T + I I F+NG K+ S IE +N+ N + + N + ++ N L+++ ++I V + I QI DNS L LDYE N F I+ + D KN + + + + +VNE P+++ S E + + E IA F TDPD N + + I + E F E + L + S + Y +++L R LSI I I + ND PT T + + E I + +F+ ++ T + +C +F I N S + A R E F +E + CF+ + S + IED+N P + D E S +G LL+ + S + S+ ++ N++ I +++S L L TEN+ L T+ D N+N S++L+V I N A ++ F+ + + E SP Sbjct: 167 SAELNYESSYVNYFVVGAYKDQILIFNKTYFI---QLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLIT-FNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSL--SNNQI----PENEPIGLLIAIINAQDNDK--------NSTLVYTLDVNEKDFYIENNKLLS--------GTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP-EIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQN--NYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVL---VSNNIKIQINEDNSFMLTDP-----------------LDYETENNFLISFTLID-KNSNQSINLKVQILDVNEAPSEIK---SFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFW-----VEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINY-LTKLTAIKESANINTVLAIFEIEDEDTDDIHQCH--GSNSYFGISNSS-----IYIAKRLDYETFTKMETIVVCFDQSGLNVSSV---FQIDIEDVNEPPENVKI--SNDQWNEKS---EIG--LLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISME-FKDVMNLPENSP 1153
BLAST of Protocadherin Fat 4 vs. Planmine SMEST
Match: SMESG000032466.1 (SMESG000032466.1) HSP 1 Score: 3570.4 bits (9257), Expect = 0.000e+0 Identity = 1848/1851 (99.84%), Postives = 1848/1851 (99.84%), Query Frame = 1 Query: 565 MILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNEL---EMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAXXXXXXXXXXXXEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMIQYPANKYFYIINCCDLMTQNLEYAWTGPLNASFIITDNGIPPMKSIFNISFNFIESKGEISATNRLINITDKANTLIGILKYSLSNSDDISFILEEVPDNAFSIIKDELWLTKDADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQYCLDXXXXXXXXXXXXXXLINQFSTYKIDFFKFISNIIEFENFTIYFNILNFDLINYRMDFSLIDNDGNVYPPEQSWDIVKQNCNFTDSLSSPAIICSELFPPVDNPKKRAENLKSQFLTYCLIFAIYWGCDGLIF 6108 MILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVSCQNSQCLNLNLNYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNEL EMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAIFEIEDEDTDDIHQCHGSNSYFGISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAISSISKDLSIKLEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMIQYPANKYFYIINCCDLMTQNLEYAWTGPLNASFIITDNGIPPMKSIFNISFNFIESKGEISATNRLINITDKANTLIGILKYSLSNSDDISFILEEVPDNAFSIIKDELWLTKDADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQYCLDSSNISNKNFNFSENLINQFSTYKIDFFKFISNIIEFENFTIYFNILNFDLINYRMDFSLIDNDGNVYPPEQSWDIVKQNCNFTDSLSSPAIICSELFPPVDNPKKRAENLKSQFLTYCLIFAIYWGCDGLIF Sbjct: 1 MILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVSCQNSQCLNLNLNYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELGAPEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINYLTKLTAIKESANINTVLAIFEIEDEDTDDIHQCHGSNSYFGISNSSIYIAKRLDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDGNFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTTINVTDVDEPLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEINISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGNFNYEILLHEIRFSIECGDAISSISKDLSIKLEDKNDPAIDLVWNGSTIIDLDLTTDGSFLGNLLVIDEDLNQMHDIMIQYPANKYFYIINCCDLMTQNLEYAWTGPLNASFIITDNGIPPMKSIFNISFNFIESKGEISATNRLINITDKANTLIGILKYSLSNSDDISFILEEVPDNAFSIIKDELWLTKDADQLSFTNITLKIRSFDQETNLPISKGNLRLEVVGISICHFNSNKCHRNATCKSNELNDEFQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFCEFDHFSCKNCSENFGVCLNLKNKNQYCLDSSNISNKNFNFSENLINQFSTYKIDFFKFISNIIEFENFTIYFNILNFDLINYRMDFSLIDNDGNVYPPEQSWDIVKQNCNFTDSLSSPAIICSELFPPVDNPKKRAENLKSQFLTYCLIFAIYWGCDGLIF 1851 HSP 2 Score: 93.2041 bits (230), Expect = 2.028e-18 Identity = 260/1067 (24.37%), Postives = 437/1067 (40.96%), Query Frame = 1 Query: 115 SCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSF-KCSVKSDSPFN---VDANFNLFTK--APLDYETQARFEVIIECLDHENSSVINKHEI--SVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNN----SLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGE-------LSAIDEDINELYSFQIL-----ILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTY--FIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSIL-----DSNLNSTIEKCSLQLITFNEIFLISQF--QLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNST---LVYTLDVNEKDFYIEN---NKLLSGTVFDHENRPGYQITITVFDNGDPKLN---VSKTFDIEILNSNE-----NPEIIIKDQYGNKTEVFHIM-----ENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKF----------EFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIE--IQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIK--IQINEDNSFMLTDPLDYETENNFL-ISFTLID-KNSNQSINLKVQILDVNEAPSEIKSFEKNLTMFEKSP 3111 S LN+ES N + KD + N FI ++D N+ P + L V ENI GS++G+ S++D +L+ + KCS++ + FN + + F L K LDYE + + I D+ +++ EI ++D NE P+ + + +N ++ EN G I +I D D+ NST V + + + K L+ G F+ ++ +QI++T +N ++S+ I ILN +ENP ++ + D NK + N LG ++ + D ++ + QI+ L EIK+ + + + L+YE + NYF + + + F FI + +VNE P L + S + ++ G SI D + N I+ L + NE F S +L LK++ DYE ++ + + + D E+ + I DAN+ P L+ IP +I +N D D ST + ++ K F I N N + T + I I F+NG K+ S IE +N+ N + + N + ++ N L+++ ++I V + I QI DNS L LDYE N F I+ + D KN + + + + +VNE P+++ S E + + E IA F TDPD N + + I + E F E + L + S + Y +++L R LSI I I + ND PT T + + E I + +F+ ++ T + +C +F I N S + A R E F +E + CF+ + S + IED+N P + D E S +G LL+ + S + S+ ++ N++ I +++S L L TEN+ L T+ D N+N S++L+V I N A ++ F+ + + E SP Sbjct: 167 SAELNYESSYVNYFVVGAYKDQILIFNKTYFI---QLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLIT-FNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSL--SNNQI----PENEPIGLLIAIINAQDNDK--------NSTLVYTLDVNEKDFYIENNKLLS--------GTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENP-EIIIKDQYGNKTEVFHIMENNELGAPEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQN--NYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVL---VSNNIKIQINEDNSFMLTDP-----------------LDYETENNFLISFTLID-KNSNQSINLKVQILDVNEAPSEIK---SFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFW-----VEILCRDDGQPSLSIQSRFYIQIINVNDGPTAINY-LTKLTAIKESANINTVLAIFEIEDEDTDDIHQCH--GSNSYFGISNSS-----IYIAKRLDYETFTKMETIVVCFDQSGLNVSSV---FQIDIEDVNEPPENVKI--SNDQWNEKS---EIG--LLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISME-FKDVMNLPENSP 1156
BLAST of Protocadherin Fat 4 vs. Planmine SMEST
Match: SMESG000032462.1 (SMESG000032462.1) HSP 1 Score: 280.411 bits (716), Expect = 1.896e-75 Identity = 137/138 (99.28%), Postives = 138/138 (100.00%), Query Frame = 1 Query: 88 ESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHE 501 ESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKH+ Sbjct: 1968 ESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHK 2105 HSP 2 Score: 155.992 bits (393), Expect = 1.803e-37 Identity = 235/953 (24.66%), Postives = 424/953 (44.49%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDS---FKCSVKSDSPFNVDANFNLFTKAPLDYE--TQARFEVIIECLDH--ENSSVINKHEISVTDINEAPDKIYV-NTTNEEMI--LTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTD----VXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRN--NNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITF-NEIFLI--SQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIE-NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYG-----NKTEV---FHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQ-----KKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQF--------FDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQ-IECSII-KPLKWFSILNISQNLEIVTTATRFIDEKFIDIE--IQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTD 2841 C LN+E+ N + + DL P + F +++ ++D ND PT I L N + E++ +G +G DED ++ + F +D N NL + +DYE +Q + ++ D+ +V + + ++NE P +V N+ +E I ++ EN+K G ++ +Y DPD ND + F+ S + + + L ++ T C+ ++ + + F+ E ++ L F + D++ N++ + +KI + E P +++ ++ S + I+EN ++ L+A + D+ F I+ EI + L +KE+ L+YES + D I +VNE P + L + + EN +G++ D +LN T + Q+I+ N F I ++ ++ + L++EK P L I VTD G N F I I D N+ P+NL L N+ + EN PIG +I + + D D N T+ Y L + F + N +++ + ++E Y +T+ +DNG P L + I + + NE P +++ N ++ F + +N+ E+ + P +NC FL + +++ FQ I + L+YE N + +N+ ++ I I V +VNE + + I+ I+I EN I+ F DPD + I+ E+S S + + +Q F++ES +I + I+ S L + + I+D N+ P L+ I +I KV +D DN + Q + SI+ + L F I I +L IV + + EK ++E IQ +NG + S ++I D+N+ P F T F+++N+ ++ + L D Sbjct: 710 CSLNYET-LNIHKITVKTVDLGTPSYTVYFDLYIQLVDMNDAPTLIVLDNISIPESLNIGDKIGSFHTFDEDNRTQIFIYEILQGNSDYFIIDQN-NLLLRQKVDYEDSSQQSLRITVKSTDNGIPPMNVSTEFILKTQNVNEPPFVSFVSNSIKQEDIYFISIEENNKIGDKLATVYVTDPDINDTVSFFIKSPNNTIFFNNTQCKTNTLKVSSTNCILDLYTK--VVFHHETKNNLSFTLISVDKHFLNSATNFFLKI--KKIPEIPKNIRFVETDSQIIEIDENIYGANISLLTADNVDLLSNLKFTIIQDEGGYFEIINDRILKLKENKCLDYESDSRKNIITVKIADA----TANLTIMARNVNEFPSDIILDNTKIFENSTTGTLFSTLDAFDPDLNKTF---TFQIISSSNSAFKIYGNEIKIITTNEIYLNFEKKPFETLEILVTDRGLLNFTAIFNIT--ILDCNDMPKNLFLPNSYVTENVPIGTIIGTLQSSDEDSNQTVRYQLLSDFITFTLSTNGTIMTSSNINYETSKLYNLTVLYYDNGVPPLTSTGAVIIYVNDLNEPPYFEMEESIALNVPENTLKLIGPFQVYDNDLNEILSMKLICVTP-----LNCNCPIKIESFLCENSILYNRTKCNFYFQ----IYKKLNYEDINSYNVNLFVSARSEQQTNKTIMISVLDVNEQISFVKINDESVRNISIKENEDVIGKISFF---DPDFSQTHTIRIIE--------EYSMDNSPILVVRNQLIRTLEDFKFNFESQNLFNITLEIKDDSSEPLIYLVSFIVIIEDINEQPGHISLSQYEISENALNGSVIAKVEAYDPDNENVTRQNLSFSILYQTLDAFEI--IGSDL-IVKNSMKLNYEKNENLELIIQVTDNGQPSLSSVEV-IEISILDVNDAP--LDFQLTDTFLSKNAGKGTIVKELYYID 1621 HSP 3 Score: 147.902 bits (372), Expect = 5.888e-35 Identity = 270/1112 (24.28%), Postives = 479/1112 (43.08%), Query Frame = 1 Query: 841 VKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSL-GELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAE--LNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERP-----ENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTL----------DVNEKDFYIENNKLLSGTV----------FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEII-IKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIIS----DNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIK----YSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSID-LEV-PISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIV-----LVSNNIKIQINEDN--------------SFMLTDPLDYETENNFLISFTLIDKNSNQSINLK-VQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDG-----PTAINYLTK-----------LTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAKRLDYETFT---KMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSL 3936 + I+ NV+E P+D+ L+++ I ENS+ +L L A D D+N+ ++FQI+ + +I + NE+ I + E LN+E + +L F + I ++D N+ P+ L L S VTEN+P G++IG D + N T+ QL++ F +S + ++ ++YE + YNL + D G + + +I+ ++D NE P E+++L+ +PEN LI DND N L L + + F EN+ L + T ++E+ Y + + V + + N KT I +L+ NE + I D+ I EN E I+ F+PDF +II DNS LV + I+ + + ++E N F I +EI D + ++ + +E++NE P +++ I+EN IA DPD +V + +SIL + FE GS L +K S +YE N ++++++I+ D+G S+ +EV ISI D ND P L T + K I+ ++ DED ++ ++ + + P +F I I+ ++ + I + + + + ++G + S S L I ++ + + + F+ +N N IS + + S LQI+ + + +VS++ K N N +L LDYE ++ IS TL N+ I + +Q+L+VNE P++I S + L + E + PN + F D D+++ F Q I+++ + ++ + N LL+ D Y EI+ R +L I+ F + I++ N+ P +N L + E+ NI+ ++ E+ N S I+ L++E+ T +E + D + + + I D N+PP N+++SN + E +G L+ +S D + + + PF + N ++F L T Q FEV + + + N S+ Sbjct: 1060 LTIMARNVNEFPSDIILDNTK-----IFENSTTGTLFSTLDAFDPDLNKTFTFQIISSSNSAFKI-YGNEIKIITTNEIYLNFEKKPFETLEILVTDRGLLNFTAIFNITILDCNDMPKNLFLPNSYVTENVPIGTIIGTLQSSDEDSNQTVR---YQLLSDFITFTLST-NGTIMTSSNINYETSKLYNLTVLYYDNGVPPLTSTGAVIIYVNDLNEPPYFEMEESIALN---VPENTL--KLIGPFQVYDNDLNEILSMKLICVTPLNCNCPIKIESFLCENSILYNRTKCNFYFQIYKKLNYEDINSYNVNLFVSARSEQQTN--KTIMISVLDVNEQISFVKINDE---SVRNISIKEN---EDVIGKISFFDPDFSQTHTIRIIEEYSMDNSPILVVRNQLIRTLEDF------KFNFESQNLFNITLEIKDDSSEPLIYLVSFIVIIEDINEQPGHISLSQYE-----ISENALNGSVIAKVEAYDPDNENVTRQNLSFSIL--YQTLDAFEII--GSDLIVKNSMKLNYEKN--ENLELIIQVTDNGQPSLSSVEVIEISILDVNDAPLDFQLTDTFLSKNAGKGTIVKELYYIDEDKNQSH-KLTIANVDPKNYFQIFEINSFNQLEKISNDEILDSEVHVTVYVADDG---VPSLNGSLELTIHIVDETLDSLN---EIRFILQNVNEISENAFI---NDSIGYLQITLARQLTFTQFRVVSSDAKQYFNFFNLTCSYEGPTTKCILEMVLISKLDYEEKSVLDISVTLGGDNNVTVIAQQDLQVLNVNERPTDIISSPEKLIVKEIALPNEVVGVFRMIDDDFDEKGHF--QMIVMSDK-----LILLENGTLLSTGKGFD-----YEKDDPSEIVIRAIDHGNLVIEKSFSLAILDQNEEIKSIIPNLVNVFENSTDNQILCSFILPGLDENQNISLIIVKNFKENFFIRKNDLVLKINESMCWEYS---ISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDED---LDDSFKCSVKSDSPFNVDANFNLFTKAPLDYET---QARFEVIIECLDHENSSV 2100 HSP 4 Score: 145.591 bits (366), Expect = 2.683e-34 Identity = 248/1046 (23.71%), Postives = 446/1046 (42.64%), Query Frame = 1 Query: 124 LNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDS-PFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYT------NSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHT--DSVEIKHKNEL-WIKESAELNYESSYVNYFVVGAYKD---QILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDS-NLNSTIEKCSLQLITFN-EIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTL-DVNEKDFY-------------IENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSN-----------ENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKIN-----CQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFI---------------DIEIQCFNNGHTKI----------------KSTTYSTALAIEDINNEPATFSF-NWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSIN 3024 LNFE K +LEIL D + + +F ++ ILD ND P N+ L N V EN+ +G+++G + DED + + + + SD F + N + T + ++YET + + + D+ + + I V D+NE P Y E + L EN+ IG D D N+ L N S ++ Y + Q N+E + + V+ R+ ++ + I +L+V+E + +K+ND + + I+EN +G++S D D ++ ++ +I+ ++ +S + +N+L E + N+ES + + + KD + LI+ ++ + + D+NE P ++L ++EN +GSVI K D N N T + S ++ + F I L +K++ +L+YEK L I+VTD GQ ++ + I + I D N+ P + L++ + +N G ++ + D DKN + T+ +V+ K+++ I N+++L V +T+ V D+G P LN S I I++ +N I ++ + N + + ++ ++TF V D N C ++ +++ + + LDYE+ + +I++ + N T I + + V NVNE PT + I ++I+ + I D D+ + ++ ++K G+ L + FDYE + +I +IRAID G L I+ ++I D N+ ++IP+ VNVF+ ST NQI CS I P L+ +QN+ ++ F + FI + I C N +K S + +AI D N+ P NW V+ NI +G L+ ++ L S V ++ ++ + + PLDYET+ F + +D ++ IN Sbjct: 1134 LNFEKKPFE-TLEILVTDRGLLNFTAIF--NITILDCNDMPKNLFLPNSYVTENVPIGTIIGTLQSSDEDSNQTVRYQLLSDFITFTLSTNGTIMTSSNINYETSKLYNLTVLYYDNGVPPLTSTGAVIIYVNDLNEPP---YFEM-EESIALNVPENTLK--LIGPFQVYDNDLNEILSMKLICVTPLNCNCPIKIESFLCENSILYNRTKCNFYFQIYKKLNYEDINSYNVNLFVSARSEQQTNKTIMISVLDVNEQISFVKINDESVRNISIKENED--VIGKISFFDPDFSQTHTIRIIEEYSMDNSPILVVRNQLIRTLEDFKFNFESQNL-FNITLEIKDDSSEPLIYLVSFIVIIEDINEQPGHISLSQYEISENALNGSVIAKVEAYDPDNENVTRQNLSFSILYQTLDAFEIIGSDLIVKNSMKLNYEKNENLELIIQVTDNGQPSLSSVEVIEISILDVNDAPLDFQLTDTFLSKNAGKGTIVKELYYIDEDKNQSHKLTIANVDPKNYFQIFEINSFNQLEKISNDEILDSEV---------HVTVYVADDGVPSLNGSLELTIHIVDETLDSLNEIRFILQNVNEISENAFINDS-IGYLQITLARQLTFTQFRVVSSDAKQYFNFFNLTCSYEGPTTKCILE------------MVLISKLDYEEKSVLDISVTLGGDNNVTVIAQQDLQVLNVNERPTDI-ISSPEKLIVKEIALPNEVVGVFRMIDDDFDEKGHFQMIVM-----SDKLILLENGT--LLSTGKGFDYEKDDPSEI--VIRAIDHGNLVIEKSFSLAILDQNEEIK------SIIPNL---------VNVFEN---STDNQILCSFILPG-----LDENQNISLIIVK-NFKENFFIRKNDLVLKINESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVE------ENILVGSLVGQISVVDEDLD---DSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVIN 2102 HSP 5 Score: 102.834 bits (255), Expect = 2.317e-21 Identity = 137/563 (24.33%), Postives = 256/563 (45.47%), Query Frame = 1 Query: 115 SCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSP------FNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTAN-----ENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXX---XXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENS-SNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSI--LDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYE-----------KTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENN-KLLSGTVFDHENRPGYQITITVFDN 1716 S LN+E K N+ L I D P S + +I ++ILD ND P + QL++ + +N G++V ++ +DED + S K ++ + P F +++ FN K D + V + D S+ E+++ ++E D + NE + N EN+ IG + + + +F S+D + + TKC+ E+ + +L ++E +S L +++ NN ++ + +LNV+E PTD+ S+ K++++E + N +G ID+D +E FQ++++ +D + I +N + +YE + V+ A L+ K++ + ++D NE + + V EN ++ F + LD N N ++ + + F E F I + L LK N + +E KT +L I D F I + I DAN+ P N+ LSN ++ EN +G L+ I+ D D + + ++ ++ F ++ N L + D+E + +++ I D+ Sbjct: 1552 SMKLNYE-KNENLELIIQVTDNGQPSLSSVEVIEISILDVNDAPLDFQLTDTFLSKNAGKGTIVKELYYIDEDKNQSHKLTIANVDPKNYFQIFEINS-FNQLEKISNDEILDSEVHVTVYVADDGVPSLNGSLELTIHIVDETLDSL-----NEIRFILQNVNEISENAFINDSIGYLQITLARQLTFTQFRVVSSDAKQYFNFFNLTCSYEGPTTKCILEMVLISKL--DYEEKSVLDISVTLGGDNNVTVIAQQDLQVLNVNERPTDII---SSPEKLIVKEIALPNEVVGVFRMIDDDFDEKGHFQMIVM-SDKL-ILLENGTLLSTGKGFDYEKDDPSEIVIRAIDHGNLVIEKSFSLAILDQNEEIKSIIPNLVNVFENSTDNQILCSFILPGLDENQNISL----IIVKNFKENFFIRKNDLVLKINESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVK-SDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDH 2095 HSP 6 Score: 84.3445 bits (207), Expect = 1.220e-15 Identity = 165/692 (23.84%), Postives = 289/692 (41.76%), Query Frame = 1 Query: 124 LNFESKT-NNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDD------SFKCSVKSDSPFNV-DANFNLFTKAPLDYETQARFEVIIECLDHENSSV--INKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLT-------EIRIQFELGFNF--ERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPST--VTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIA--IINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLN------VSKTFDI-----------EILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMK 2079 NFES+ NI+LEI KD L V I D N+ P +I LS +++ EN L GS++ ++ D D ++ SF ++ F + ++ + L+YE E+II+ D+ S+ + EIS+ D+N+AP + T ++N+ GT + +Y D D+N + + D + N + ++ E+ + + + L I + D +SL+EI + I+ NV+E + +NDS L + + + + D + ++F L + K E+ + ++L+YE V V D + +Q+++VNE P + P V E V+G F ++D + + EK Q+I ++ ++ + L DYEK + IR D+G N+V + L I D NE +++ + + EN ++ I+ D ++N +L+ + E +F+I N L V ++ +I+ N + K N ++K D+ IL++N+ P I Q N + + EN + I+V + D DD C + SD S F V ++L LDYE FE+ IE D +N + I K Sbjct: 1451 FNFESQNLFNITLEI--KDDSSEPLIYLVSFIVIIEDINEQPGHISLSQYEISENALNGSVIAKVEAYDPDNENVTRQNLSFSILYQTLDAFEIIGSDLIVKNSMKLNYEKNENLELIIQVTDNGQPSLSSVEVIEISILDVNDAPLDFQLTDT------FLSKNAGKGTIVKELYYIDEDKNQSHKLTIANVDPKNYFQIFEINSFNQLEKISNDEILDSEVHVTVYVADDGVPSLNGSLELTIHIVDETLDSLNEI-RFILQNVNEISENAFINDSIG--YLQITLARQLTFTQFRVVSSDAKQYFNFFNLTCSYEGPTTKCILEMVL--ISKLDYEEKSVLDISVTLGGDNNVTVIAQQDLQVLNVNERPTDIISSPEKLIVKEIALPNEVVGVFRMIDDDFD---EKGHFQMIVMSDKLILLENGTLLSTGKGFDYEKDDPSEIVIRAIDHG--NLVIEKSFSLAILDQNEEIKSIIPNLVNVFENSTDNQILCSFILPGLDENQNISLIIVKNFKE-NFFIRKNDL----VLKINESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNI---QLSN----WKVEENILVGSLVGQISVVDEDLDDSFKCSVKSD-SPFNVDA--------NFNLFTKAPLDYETQARFEVIIECLDHENSSVINK 2103 HSP 7 Score: 70.8626 bits (172), Expect = 1.313e-11 Identity = 268/1141 (23.49%), Postives = 470/1141 (41.19%), Query Frame = 1 Query: 232 ANDPPTNIQLSNWKVEENILVGSLVGQISVVD-EDLDDSFKCSVKSDSPFNVDANFNLF-TKAPLDYE-----TQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRN-------------DYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDEN--PTDLKLNDSTSNKVLIEENSSNYSLGELSAIDED-INELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKT--YFIQLIDVNEAP---------QGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIE---KCSLQLITFN------EIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSL--SNNQIPE-NEPI-GLLIAIINAQDNDKNSTLVYTLDVNEKDFY-IENNKLLS---GTVFDHENRPGYQ-ITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVA-----GLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNL---EIVTTATR----FIDEKFIDIE------IQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFN-WTVDFVTENSNNISLGQLLLM-TDYSNKSL-----QISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLK---VQILDVNEAPSEIKSFEKNLTMFEKSPPNIH---IATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCR--DDGQPSLSIQSRFYIQIINVNDGP 3393 N PPT+I + N KVEE + D L D+F S+ + N + + T+ L+Y + + V I+ D N S ISVTDINE P + N+ EN G +G + D D+N + E + NST + + ++ N CL + L N+E + + D S + + I VD N PT + L+ N + E + +G DED +++ ++IL ++D I +N L +++ + S V + + I N + + ++ +VNE P + +Y ++ EN G + + D ++N T+ K I FN +S L T++ + NL + + + + L+I E P+N+ +++QI E +E I G I+++ A + D S L +T+ +E ++ I N+++L D+E+ IT+ + D + I N NE P II D T++F EN+ F+T+ F+PD + QIIS ++ +EIK I ++ +N +E+ + + I + D + NFTAI I I + N+ P L + S +TEN+ I ++D D N ++Y +L+ F S G+ + S +YE++ ++ VL L+ V I + D N+PP LN +P K +IG V+D D L+ ++ + PL + I L I+ T+ F K ++ E + F + ++ + T + +++ D+N + + N +V ++ N +G++ D+S + S + +LV N I+ ED F ++E++N F I+ + D +S I L V I D+NE P I +L+ +E S ++ IA A DPD + ++ I+ + +I+ ++L+ NS+ + NY +E++ + D+GQPSLS I I++VND P Sbjct: 527 PNYPPTDILIDNTKVEEETSNNECFANLGTKDLNGLLDTFVYSLVN----NFENRLQIMGTQLCLNYRPNYEASNNTWLVKIKTTDSGNLSFQKSINISVTDINEPPTSCSFDRVNK-----IPENVGYGYFVGYLTLLDEDKNFRQFKETIFDSDSNTFEVFYNSTQLVFKYGIRVSKNET-ADCLRKGGAFCSL--NYETLNIHKITVKTVDLGTPSYTVYFDLYIQLVDMNDAPTLIVLD----NISIPESLNIGDKIGSFHTFDEDNRTQIFIYEILQGNSDYF-IIDQNNLLLRQKVDYEDSSQQSLRITVKSTDNGIPPMNVSTEFILKTQNVNEPPFVSFVSNSIKQEDIYFISIEENNKIGDKLATVYVTDPDINDTVSFFIKSPNNTIFFNNTQCKTNTLKVSSTNCILDLYTKVVFHHETKNNLSFTLISVDKHFLNSATNFFLKIKKIPEIPKNIRFVETDSQIIEIDENIYGANISLLTADNVDLLSNLKFTIIQDEGGYFEIINDRILKLKENKCLDYESDSRKNIITVKIAD-------ATANLTIMARNVNEFPSDIILDN----TKIF---ENSTTGTLFSTLDAFDPDLNKTFTFQIISSSNSAFKIYGNEIKIITTNEIYLN----FEKKPFETLEILVTDRGLLNFTAIFNITIL--DCNDMPKNLFLPNSY-----VTENVPIGTIIGTLQSSDEDSNQTVRYQLLSDF---ITFTLSTNGT---IMTSSNINYETSKLYNLTVLYYDNGVPPLTSTGAVIIYVNDLNEPPYFEMEESIALN---VPENTLK--LIGPFQVYDND-LNEILSMKLICVTPLNCNCPIKIESFLCENSILYNRTKCNFYFQIYKKLNYEDINSYNVNLFVSARSE-QQTNKTIMISVLDVNEQISFVKINDESVRNISIKENEDVIGKISFFDPDFSQTHTIRIIEEYSMDNSPILVVRNQLIRTLEDFKF------NFESQNLFNITLEIKDDSSEPLIYLVSFIVIIEDINEQPGHI-----SLSQYEISENALNGSVIAKVEAYDPDNENVTRQNLSFSILYQTL---DAFEIIGSDLIVK-NSMKL---NYEKNENLELIIQVTDNGQPSLSSVEVIEISILDVNDAP 1594 HSP 8 Score: 67.781 bits (164), Expect = 1.149e-10 Identity = 200/873 (22.91%), Postives = 351/873 (40.21%), Query Frame = 1 Query: 2086 IFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQN-DVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLN-FTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIE----IQCFNNGHTKIKSTTYST------ALAIEDINNEPATFSFNWTVDFVTENS-------NNISLGQLLLMTD-----YSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS-----NQSINLKVQILDVNEAPSEIKSFEKN---------LTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSI------------QSRFYIQIINVNDGPTAINYLTKLTAIKE------SANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAKR---LDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQV-QFVLNSCKNVECPFY-----ILQNSSIFLN---KSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDG-NFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTT-INVTDVDE-PLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEIN-ISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGN 4488 ++ N PPT + ID ++ + E + AN T D + D YS++N N + G++L L ++ +N V I+ DSG LS + IS+ D N+PPT + IP V + +G + + DED + Q + +I + S E+ +T+ + + I + C G S Y T + D+ T F+ + V N +NIS+ + L + D ++ ++ I ++ N I + N+ +L +DYE + + T+ ++ N S ++ +VNE P SF N +++ E + +AT Y TDPD N SF I K N FN++ K N+L V +N I + +++ + + +LS + F+++I + + P I ++ + I E ANI ++L ++ YF I N I K LDYE+ ++ I V + N++ I +VNE P ++ + N + E S G L + L A DP+ ++ F + S N Y I+ + I+LN K + L E+ V+D N + +TI N ++ F + EN PIG+ + +Q + + + ++ SD F + + ++ + +++YET+ +TV + N + L I V D++E P E+ +I ++ E T K IG + D ++N I ++K + CVT PL NC + F+ N Sbjct: 522 MYCGQPNYPPTDILIDNTK-----VEEETSNNECFANLGTKDLNGLLDTFVYSLVN----NFENRLQIMGTQLCLNYRPNYEASNNTWL---VKIKTTDSGNLSFQKSINISVTDINEPPTSCSFDRVNKIPENVGYGYFVGYLTLLDED--KNFRQFKETIFD--------SDSNTFEVFYNSTQLVFKYGIRVSKNETADCLRKGGA-FCSLNYETLNIHKITVKTVDLGTPSYTVYFDLYIQLVDMNDAPTLIVLDNISIPESLNIGDKIGSFHTFDEDNRTQIFIYEILQGNSDYFIIDQNNLLLRQKVDYEDSSQQSLRITVKSTDNGIPPMNVSTEFILKTQNVNEPP--FVSFVSNSIKQEDIYFISIEENNKIGDKLATVYVTDPDINDTVSFFI-KSPNNTIFFNNTQCK---------TNTLKVSSTNCILDLYTKVVFHHETKNNLSFTLISVDKHFLNSATNFFLKIKKIPEIPKNIRFVETDSQIIEIDENIYGANI-SLLTADNVDLLSNLKFTIIQDEGGYFEIINDRILKLKENKCLDYESDSRKNIITVKIADATANLT----IMARNVNEFPSDIILDNTKIFENSTTGTLFSTLDAFDPDLNKTFTFQIISSSNSAFKIYGNEIKIITTNEIYLNFEKKPFETL--------EILVTDRGLLNFTAIFNITILDCNDMPKNL-FLPNSYVTENVPIGTIIGTLQ-SSDEDSNQTVRYQLLSDFITFTLSTNGTIMTSSNINYETSKLYNLTVLYYDNGVPPLTSTGAVIIYVNDLNEPPYFEMEESIALNVPEN--TLKLIGPFQVYDNDLNEILSMKLI-------------CVT-PLNCNCPIKIESFLCEN 1328
BLAST of Protocadherin Fat 4 vs. Planmine SMEST
Match: SMESG000032462.1 (SMESG000032462.1) HSP 1 Score: 280.411 bits (716), Expect = 2.010e-75 Identity = 137/138 (99.28%), Postives = 138/138 (100.00%), Query Frame = 1 Query: 88 ESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHE 501 ESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKH+ Sbjct: 1954 ESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHK 2091 HSP 2 Score: 155.606 bits (392), Expect = 2.539e-37 Identity = 235/953 (24.66%), Postives = 424/953 (44.49%), Query Frame = 1 Query: 118 CPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDS---FKCSVKSDSPFNVDANFNLFTKAPLDYE--TQARFEVIIECLDH--ENSSVINKHEISVTDINEAPDKIYV-NTTNEEMI--LTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTD----VXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRN--NNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITF-NEIFLI--SQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIE-NNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYG-----NKTEV---FHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQ-----KKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQF--------FDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQ-IECSII-KPLKWFSILNISQNLEIVTTATRFIDEKFIDIE--IQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTD 2841 C LN+E+ N + + DL P + F +++ ++D ND PT I L N + E++ +G +G DED ++ + F +D N NL + +DYE +Q + ++ D+ +V + + ++NE P +V N+ +E I ++ EN+K G ++ +Y DPD ND + F+ S + + + L ++ T C+ ++ + + F+ E ++ L F + D++ N++ + +KI + E P +++ ++ S + I+EN ++ L+A + D+ F I+ EI + L +KE+ L+YES + D I +VNE P + L + + EN +G++ D +LN T + Q+I+ N F I ++ ++ + L++EK P L I VTD G N F I I D N+ P+NL L N+ + EN PIG +I + + D D N T+ Y L + F + N +++ + ++E Y +T+ +DNG P L + I + + NE P +++ N ++ F + +N+ E+ + P +NC FL + +++ FQ I + L+YE N + +N+ ++ I I V +VNE + + I+ I+I EN I+ F DPD + I+ E+S S + + +Q F++ES +I + I+ S L + + I+D N+ P L+ I +I KV +D DN + Q + SI+ + L F I I +L IV + + EK ++E IQ +NG + S ++I D+N+ P F T F+++N+ ++ + L D Sbjct: 696 CSLNYET-LNIHKITVKTVDLGTPSYTVYFDLYIQLVDMNDAPTLIVLDNISIPESLNIGDKIGSFHTFDEDNRTQIFIYEILQGNSDYFIIDQN-NLLLRQKVDYEDSSQQSLRITVKSTDNGIPPMNVSTEFILKTQNVNEPPFVSFVSNSIKQEDIYFISIEENNKIGDKLATVYVTDPDINDTVSFFIKSPNNTIFFNNTQCKTNTLKVSSTNCILDLYTK--VVFHHETKNNLSFTLISVDKHFLNSATNFFLKI--KKIPEIPKNIRFVETDSQIIEIDENIYGANISLLTADNVDLLSNLKFTIIQDEGGYFEIINDRILKLKENKCLDYESDSRKNIITVKIADA----TANLTIMARNVNEFPSDIILDNTKIFENSTTGTLFSTLDAFDPDLNKTF---TFQIISSSNSAFKIYGNEIKIITTNEIYLNFEKKPFETLEILVTDRGLLNFTAIFNIT--ILDCNDMPKNLFLPNSYVTENVPIGTIIGTLQSSDEDSNQTVRYQLLSDFITFTLSTNGTIMTSSNINYETSKLYNLTVLYYDNGVPPLTSTGAVIIYVNDLNEPPYFEMEESIALNVPENTLKLIGPFQVYDNDLNEILSMKLICVTP-----LNCNCPIKIESFLCENSILYNRTKCNFYFQ----IYKKLNYEDINSYNVNLFVSARSEQQTNKTIMISVLDVNEQISFVKINDESVRNISIKENEDVIGKISFF---DPDFSQTHTIRIIE--------EYSMDNSPILVVRNQLIRTLEDFKFNFESQNLFNITLEIKDDSSEPLIYLVSFIVIIEDINEQPGHISLSQYEISENALNGSVIAKVEAYDPDNENVTRQNLSFSILYQTLDAFEI--IGSDL-IVKNSMKLNYEKNENLELIIQVTDNGQPSLSSVEV-IEISILDVNDAP--LDFQLTDTFLSKNAGKGTIVKELYYID 1607 HSP 3 Score: 147.517 bits (371), Expect = 7.008e-35 Identity = 270/1112 (24.28%), Postives = 479/1112 (43.08%), Query Frame = 1 Query: 841 VKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSL-GELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAE--LNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERP-----ENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTL----------DVNEKDFYIENNKLLSGTV----------FDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSNENPEII-IKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIIS----DNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIK----YSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSID-LEV-PISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIEIQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFNWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIV-----LVSNNIKIQINEDN--------------SFMLTDPLDYETENNFLISFTLIDKNSNQSINLK-VQILDVNEAPSEIKSFEKNLTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSIQSRFYIQIINVNDG-----PTAINYLTK-----------LTAIKESANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAKRLDYETFT---KMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQVQFVLNSCKNVECPFYILQNSSIFLNKSLQVLTENDQLEFEVTVSDILNTNVSL 3936 + I+ NV+E P+D+ L+++ I ENS+ +L L A D D+N+ ++FQI+ + +I + NE+ I + E LN+E + +L F + I ++D N+ P+ L L S VTEN+P G++IG D + N T+ QL++ F +S + ++ ++YE + YNL + D G + + +I+ ++D NE P E+++L+ +PEN LI DND N L L + + F EN+ L + T ++E+ Y + + V + + N KT I +L+ NE + I D+ I EN E I+ F+PDF +II DNS LV + I+ + + ++E N F I +EI D + ++ + +E++NE P +++ I+EN IA DPD +V + +SIL + FE GS L +K S +YE N ++++++I+ D+G S+ +EV ISI D ND P L T + K I+ ++ DED ++ ++ + + P +F I I+ ++ + I + + + + ++G + S S L I ++ + + + F+ +N N IS + + S LQI+ + + +VS++ K N N +L LDYE ++ IS TL N+ I + +Q+L+VNE P++I S + L + E + PN + F D D+++ F Q I+++ + ++ + N LL+ D Y EI+ R +L I+ F + I++ N+ P +N L + E+ NI+ ++ E+ N S I+ L++E+ T +E + D + + + I D N+PP N+++SN + E +G L+ +S D + + + PF + N ++F L T Q FEV + + + N S+ Sbjct: 1046 LTIMARNVNEFPSDIILDNTK-----IFENSTTGTLFSTLDAFDPDLNKTFTFQIISSSNSAFKI-YGNEIKIITTNEIYLNFEKKPFETLEILVTDRGLLNFTAIFNITILDCNDMPKNLFLPNSYVTENVPIGTIIGTLQSSDEDSNQTVR---YQLLSDFITFTLST-NGTIMTSSNINYETSKLYNLTVLYYDNGVPPLTSTGAVIIYVNDLNEPPYFEMEESIALN---VPENTL--KLIGPFQVYDNDLNEILSMKLICVTPLNCNCPIKIESFLCENSILYNRTKCNFYFQIYKKLNYEDINSYNVNLFVSARSEQQTN--KTIMISVLDVNEQISFVKINDE---SVRNISIKEN---EDVIGKISFFDPDFSQTHTIRIIEEYSMDNSPILVVRNQLIRTLEDF------KFNFESQNLFNITLEIKDDSSEPLIYLVSFIVIIEDINEQPGHISLSQYE-----ISENALNGSVIAKVEAYDPDNENVTRQNLSFSIL--YQTLDAFEII--GSDLIVKNSMKLNYEKN--ENLELIIQVTDNGQPSLSSVEVIEISILDVNDAPLDFQLTDTFLSKNAGKGTIVKELYYIDEDKNQSH-KLTIANVDPKNYFQIFEINSFNQLEKISNDEILDSEVHVTVYVADDG---VPSLNGSLELTIHIVDETLDSLN---EIRFILQNVNEISENAFI---NDSIGYLQITLARQLTFTQFRVVSSDAKQYFNFFNLTCSYEGPTTKCILEMVLISKLDYEEKSVLDISVTLGGDNNVTVIAQQDLQVLNVNERPTDIISSPEKLIVKEIALPNEVVGVFRMIDDDFDEKGHF--QMIVMSDK-----LILLENGTLLSTGKGFD-----YEKDDPSEIVIRAIDHGNLVIEKSFSLAILDQNEEIKSIIPNLVNVFENSTDNQILCSFILPGLDENQNISLIIVKNFKENFFIRKNDLVLKINESMCWEYS---ISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDED---LDDSFKCSVKSDSPFNVDANFNLFTKAPLDYET---QARFEVIIECLDHENSSV 2086 HSP 4 Score: 145.206 bits (365), Expect = 3.875e-34 Identity = 248/1046 (23.71%), Postives = 446/1046 (42.64%), Query Frame = 1 Query: 124 LNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDS-PFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHE--ISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYT------NSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHT--DSVEIKHKNEL-WIKESAELNYESSYVNYFVVGAYKD---QILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSILDS-NLNSTIEKCSLQLITFN-EIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTL-DVNEKDFY-------------IENNKLLSGTVFDHENRPGYQITITVFDNGDPKLNVSKTFDIEILNSN-----------ENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKIN-----CQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFI---------------DIEIQCFNNGHTKI----------------KSTTYSTALAIEDINNEPATFSF-NWTVDFVTENSNNISLGQLLLMTDYSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSIN 3024 LNFE K +LEIL D + + +F ++ ILD ND P N+ L N V EN+ +G+++G + DED + + + + SD F + N + T + ++YET + + + D+ + + I V D+NE P Y E + L EN+ IG D D N+ L N S ++ Y + Q N+E + + V+ R+ ++ + I +L+V+E + +K+ND + + I+EN +G++S D D ++ ++ +I+ ++ +S + +N+L E + N+ES + + + KD + LI+ ++ + + D+NE P ++L ++EN +GSVI K D N N T + S ++ + F I L +K++ +L+YEK L I+VTD GQ ++ + I + I D N+ P + L++ + +N G ++ + D DKN + T+ +V+ K+++ I N+++L V +T+ V D+G P LN S I I++ +N I ++ + N + + ++ ++TF V D N C ++ +++ + + LDYE+ + +I++ + N T I + + V NVNE PT + I ++I+ + I D D+ + ++ ++K G+ L + FDYE + +I +IRAID G L I+ ++I D N+ ++IP+ VNVF+ ST NQI CS I P L+ +QN+ ++ F + FI + I C N +K S + +AI D N+ P NW V+ NI +G L+ ++ L S V ++ ++ + + PLDYET+ F + +D ++ IN Sbjct: 1120 LNFEKKPFE-TLEILVTDRGLLNFTAIF--NITILDCNDMPKNLFLPNSYVTENVPIGTIIGTLQSSDEDSNQTVRYQLLSDFITFTLSTNGTIMTSSNINYETSKLYNLTVLYYDNGVPPLTSTGAVIIYVNDLNEPP---YFEM-EESIALNVPENTLK--LIGPFQVYDNDLNEILSMKLICVTPLNCNCPIKIESFLCENSILYNRTKCNFYFQIYKKLNYEDINSYNVNLFVSARSEQQTNKTIMISVLDVNEQISFVKINDESVRNISIKENED--VIGKISFFDPDFSQTHTIRIIEEYSMDNSPILVVRNQLIRTLEDFKFNFESQNL-FNITLEIKDDSSEPLIYLVSFIVIIEDINEQPGHISLSQYEISENALNGSVIAKVEAYDPDNENVTRQNLSFSILYQTLDAFEIIGSDLIVKNSMKLNYEKNENLELIIQVTDNGQPSLSSVEVIEISILDVNDAPLDFQLTDTFLSKNAGKGTIVKELYYIDEDKNQSHKLTIANVDPKNYFQIFEINSFNQLEKISNDEILDSEV---------HVTVYVADDGVPSLNGSLELTIHIVDETLDSLNEIRFILQNVNEISENAFINDS-IGYLQITLARQLTFTQFRVVSSDAKQYFNFFNLTCSYEGPTTKCILE------------MVLISKLDYEEKSVLDISVTLGGDNNVTVIAQQDLQVLNVNERPTDI-ISSPEKLIVKEIALPNEVVGVFRMIDDDFDEKGHFQMIVM-----SDKLILLENGT--LLSTGKGFDYEKDDPSEI--VIRAIDHGNLVIEKSFSLAILDQNEEIK------SIIPNL---------VNVFEN---STDNQILCSFILPG-----LDENQNISLIIVK-NFKENFFIRKNDLVLKINESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVE------ENILVGSLVGQISVVDEDLD---DSFKCSVKSDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVIN 2088 HSP 5 Score: 102.834 bits (255), Expect = 2.691e-21 Identity = 137/563 (24.33%), Postives = 256/563 (45.47%), Query Frame = 1 Query: 115 SCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVKSDSP------FNVDANFNLFTKAPLDYETQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTAN-----ENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXX---XXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENS-SNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPSTVTENIPSGSVIGKFSI--LDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYE-----------KTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIAIINAQDNDKNSTLVYTLDVNEKDFYIENN-KLLSGTVFDHENRPGYQITITVFDN 1716 S LN+E K N+ L I D P S + +I ++ILD ND P + QL++ + +N G++V ++ +DED + S K ++ + P F +++ FN K D + V + D S+ E+++ ++E D + NE + N EN+ IG + + + +F S+D + + TKC+ E+ + +L ++E +S L +++ NN ++ + +LNV+E PTD+ S+ K++++E + N +G ID+D +E FQ++++ +D + I +N + +YE + V+ A L+ K++ + ++D NE + + V EN ++ F + LD N N ++ + + F E F I + L LK N + +E KT +L I D F I + I DAN+ P N+ LSN ++ EN +G L+ I+ D D + + ++ ++ F ++ N L + D+E + +++ I D+ Sbjct: 1538 SMKLNYE-KNENLELIIQVTDNGQPSLSSVEVIEISILDVNDAPLDFQLTDTFLSKNAGKGTIVKELYYIDEDKNQSHKLTIANVDPKNYFQIFEINS-FNQLEKISNDEILDSEVHVTVYVADDGVPSLNGSLELTIHIVDETLDSL-----NEIRFILQNVNEISENAFINDSIGYLQITLARQLTFTQFRVVSSDAKQYFNFFNLTCSYEGPTTKCILEMVLISKL--DYEEKSVLDISVTLGGDNNVTVIAQQDLQVLNVNERPTDII---SSPEKLIVKEIALPNEVVGVFRMIDDDFDEKGHFQMIVM-SDKL-ILLENGTLLSTGKGFDYEKDDPSEIVIRAIDHGNLVIEKSFSLAILDQNEEIKSIIPNLVNVFENSTDNQILCSFILPGLDENQNISL----IIVKNFKENFFIRKNDLVLKINESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDDSFKCSVK-SDSPFNVDANFNLFTKAPLDYETQARFEVIIECLDH 2081 HSP 6 Score: 83.9593 bits (206), Expect = 1.594e-15 Identity = 165/692 (23.84%), Postives = 289/692 (41.76%), Query Frame = 1 Query: 124 LNFESKT-NNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNIQLSNWKVEENILVGSLVGQISVVDEDLDD------SFKCSVKSDSPFNV-DANFNLFTKAPLDYETQARFEVIIECLDHENSSV--INKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRNDYLEFYTNSTDVXXXXXXXXXXXXXYTKCLT-------EIRIQFELGFNF--ERQSELYFQISVTDRNNNSLSEIVKIIILNVDENPTDLKLNDSTSNKVLIEENSSNYSLGELSAIDEDINELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKTYFIQLIDVNEAPQGLTLYPST--VTENIPSGSVIGKFSILDSNLNSTIEKCSLQLITFNEIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSLSNNQIPENEPIGLLIA--IINAQDNDKNSTLVYTLDVNEKDFYIENNKLLSGTVFDHENRPGYQITITVFDNGDPKLN------VSKTFDI-----------EILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEINDMKNFTAIMK 2079 NFES+ NI+LEI KD L V I D N+ P +I LS +++ EN L GS++ ++ D D ++ SF ++ F + ++ + L+YE E+II+ D+ S+ + EIS+ D+N+AP + T ++N+ GT + +Y D D+N + + D + N + ++ E+ + + + L I + D +SL+EI + I+ NV+E + +NDS L + + + + D + ++F L + K E+ + ++L+YE V V D + +Q+++VNE P + P V E V+G F ++D + + EK Q+I ++ ++ + L DYEK + IR D+G N+V + L I D NE +++ + + EN ++ I+ D ++N +L+ + E +F+I N L V ++ +I+ N + K N ++K D+ IL++N+ P I Q N + + EN + I+V + D DD C + SD S F V ++L LDYE FE+ IE D +N + I K Sbjct: 1437 FNFESQNLFNITLEI--KDDSSEPLIYLVSFIVIIEDINEQPGHISLSQYEISENALNGSVIAKVEAYDPDNENVTRQNLSFSILYQTLDAFEIIGSDLIVKNSMKLNYEKNENLELIIQVTDNGQPSLSSVEVIEISILDVNDAPLDFQLTDT------FLSKNAGKGTIVKELYYIDEDKNQSHKLTIANVDPKNYFQIFEINSFNQLEKISNDEILDSEVHVTVYVADDGVPSLNGSLELTIHIVDETLDSLNEI-RFILQNVNEISENAFINDSIG--YLQITLARQLTFTQFRVVSSDAKQYFNFFNLTCSYEGPTTKCILEMVL--ISKLDYEEKSVLDISVTLGGDNNVTVIAQQDLQVLNVNERPTDIISSPEKLIVKEIALPNEVVGVFRMIDDDFD---EKGHFQMIVMSDKLILLENGTLLSTGKGFDYEKDDPSEIVIRAIDHG--NLVIEKSFSLAILDQNEEIKSIIPNLVNVFENSTDNQILCSFILPGLDENQNISLIIVKNFKE-NFFIRKNDL----VLKINESMCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPPTNI---QLSN----WKVEENILVGSLVGQISVVDEDLDDSFKCSVKSD-SPFNVDA--------NFNLFTKAPLDYETQARFEVIIECLDHENSSVINK 2089 HSP 7 Score: 70.4774 bits (171), Expect = 1.731e-11 Identity = 268/1141 (23.49%), Postives = 470/1141 (41.19%), Query Frame = 1 Query: 232 ANDPPTNIQLSNWKVEENILVGSLVGQISVVD-EDLDDSFKCSVKSDSPFNVDANFNLF-TKAPLDYE-----TQARFEVIIECLDHENSSVINKHEISVTDINEAPDKIYVNTTNEEMILTANENSKSGTRIGVIYCNDPDRN-------------DYLEFYTNSTDVXXXXXXXXXXXXXYTKCLTEIRIQFELGFNFERQSELYFQISVTDRNNNSLSEIVKIIILNVDEN--PTDLKLNDSTSNKVLIEENSSNYSLGELSAIDED-INELYSFQILILHTDSVEIKHKNELWIKESAELNYESSYVNYFVVGAYKDQILIFNKT--YFIQLIDVNEAP---------QGLTLYPSTVTENIPSGSVIGKFSILDSNLNSTIE---KCSLQLITFN------EIFLISQFQLELKDNTRLDYEKTPAYNLGIRVTDYGQENIVTDFEIILEISDANERPENLSL--SNNQIPE-NEPI-GLLIAIINAQDNDKNSTLVYTLDVNEKDFY-IENNKLLS---GTVFDHENRPGYQ-ITITVFDNGDPKLNVSKTFDIEILNSNENPEIIIKDQYGNKTEVFHIMENNELEMTFATITVFEPDFDDKINCQIISDNSRFLVQKKSEIKNIFQYDLTINQTLDYEQNNYFEINIEIND--MKNFTAIMKIFIFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQNDVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVA-----GLNFTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNL---EIVTTATR----FIDEKFIDIE------IQCFNNGHTKIKSTTYSTALAIEDINNEPATFSFN-WTVDFVTENSNNISLGQLLLM-TDYSNKSL-----QISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNSNQSINLK---VQILDVNEAPSEIKSFEKNLTMFEKSPPNIH---IATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCR--DDGQPSLSIQSRFYIQIINVNDGP 3393 N PPT+I + N KVEE + D L D+F S+ + N + + T+ L+Y + + V I+ D N S ISVTDINE P + N+ EN G +G + D D+N + E + NST + + ++ N CL + L N+E + + D S + + I VD N PT + L+ N + E + +G DED +++ ++IL ++D I +N L +++ + S V + + I N + + ++ +VNE P + +Y ++ EN G + + D ++N T+ K I FN +S L T++ + NL + + + + L+I E P+N+ +++QI E +E I G I+++ A + D S L +T+ +E ++ I N+++L D+E+ IT+ + D + I N NE P II D T++F EN+ F+T+ F+PD + QIIS ++ +EIK I ++ +N +E+ + + I + D + NFTAI I I + N+ P L + S +TEN+ I ++D D N ++Y +L+ F S G+ + S +YE++ ++ VL L+ V I + D N+PP LN +P K +IG V+D D L+ ++ + PL + I L I+ T+ F K ++ E + F + ++ + T + +++ D+N + + N +V ++ N +G++ D+S + S + +LV N I+ ED F ++E++N F I+ + D +S I L V I D+NE P I +L+ +E S ++ IA A DPD + ++ I+ + +I+ ++L+ NS+ + NY +E++ + D+GQPSLS I I++VND P Sbjct: 513 PNYPPTDILIDNTKVEEETSNNECFANLGTKDLNGLLDTFVYSLVN----NFENRLQIMGTQLCLNYRPNYEASNNTWLVKIKTTDSGNLSFQKSINISVTDINEPPTSCSFDRVNK-----IPENVGYGYFVGYLTLLDEDKNFRQFKETIFDSDSNTFEVFYNSTQLVFKYGIRVSKNET-ADCLRKGGAFCSL--NYETLNIHKITVKTVDLGTPSYTVYFDLYIQLVDMNDAPTLIVLD----NISIPESLNIGDKIGSFHTFDEDNRTQIFIYEILQGNSDYF-IIDQNNLLLRQKVDYEDSSQQSLRITVKSTDNGIPPMNVSTEFILKTQNVNEPPFVSFVSNSIKQEDIYFISIEENNKIGDKLATVYVTDPDINDTVSFFIKSPNNTIFFNNTQCKTNTLKVSSTNCILDLYTKVVFHHETKNNLSFTLISVDKHFLNSATNFFLKIKKIPEIPKNIRFVETDSQIIEIDENIYGANISLLTADNVDLLSNLKFTIIQDEGGYFEIINDRILKLKENKCLDYESDSRKNIITVKIAD-------ATANLTIMARNVNEFPSDIILDN----TKIF---ENSTTGTLFSTLDAFDPDLNKTFTFQIISSSNSAFKIYGNEIKIITTNEIYLN----FEKKPFETLEILVTDRGLLNFTAIFNITIL--DCNDMPKNLFLPNSY-----VTENVPIGTIIGTLQSSDEDSNQTVRYQLLSDF---ITFTLSTNGT---IMTSSNINYETSKLYNLTVLYYDNGVPPLTSTGAVIIYVNDLNEPPYFEMEESIALN---VPENTLK--LIGPFQVYDND-LNEILSMKLICVTPLNCNCPIKIESFLCENSILYNRTKCNFYFQIYKKLNYEDINSYNVNLFVSARSE-QQTNKTIMISVLDVNEQISFVKINDESVRNISIKENEDVIGKISFFDPDFSQTHTIRIIEEYSMDNSPILVVRNQLIRTLEDFKF------NFESQNLFNITLEIKDDSSEPLIYLVSFIVIIEDINEQPGHI-----SLSQYEISENALNGSVIAKVEAYDPDNENVTRQNLSFSILYQTL---DAFEIIGSDLIVK-NSMKL---NYEKNENLELIIQVTDNGQPSLSSVEVIEISILDVNDAP 1580 HSP 8 Score: 67.781 bits (164), Expect = 1.281e-10 Identity = 200/873 (22.91%), Postives = 351/873 (40.21%), Query Frame = 1 Query: 2086 IFVENVNEPPTKLAIDGSREIIINITENIQGYQSIANFITTDPDQN-DVIKYSILNCLNCNEKFEFSNGGSKLYLKESQFFDYESNIGKDIKVLIRAIDSGGLSIDLEVPISIQDANDPPTVAGLN-FTMIPSFVEKDFIIGKVNVFDEDNLSTYNQIECSIIKPLKWFSILNISQNLEIVTTATRFIDEKFIDIE----IQCFNNGHTKIKSTTYST------ALAIEDINNEPATFSFNWTVDFVTENS-------NNISLGQLLLMTD-----YSNKSLQISKSSIIVLVSNNIKIQINEDNSFMLTDPLDYETENNFLISFTLIDKNS-----NQSINLKVQILDVNEAPSEIKSFEKN---------LTMFEKSPPNIHIATFYATDPDYNQIHSFDIQKIIVNGEIFNHSIVKIVNNELLTDVNSLDVVVSNYITYFWVEILCRDDGQPSLSI------------QSRFYIQIINVNDGPTAINYLTKLTAIKE------SANINTVLAXXXXXXXXXXXXHQCHGSNSYFGISNSSIYIAKR---LDYETFTKMETIVVCFDQSGLNVSSVFQIDIEDVNEPPENVKISNDQWNEKSEIGLLIANLSANDPEGSQV-QFVLNSCKNVECPFY-----ILQNSSIFLN---KSLQVLTENDQLEFEVTVSDILNTNVSLSLEVTIFRENLAQISMEFKDVMNLPENSPIGSKVLEIQINFLSNFMPNINCEIFSDG-NFFIIVDFKVLLNKSLDYETNSHIMVTVKCFQNKLQILKKLSTT-INVTDVDE-PLKEIIVNITDSIQEGLYTNKYIGNIIIKDPEIN-ISAIKCVAFNISLYFTNDKNCVTLPLMDNCDLSFNLFISGN 4488 ++ N PPT + ID ++ + E + AN T D + D YS++N N + G++L L ++ +N V I+ DSG LS + IS+ D N+PPT + IP V + +G + + DED + Q + +I + S E+ +T+ + + I + C G S Y T + D+ T F+ + V N +NIS+ + L + D ++ ++ I ++ N I + N+ +L +DYE + + T+ ++ N S ++ +VNE P SF N +++ E + +AT Y TDPD N SF I K N FN++ K N+L V +N I + +++ + + +LS + F+++I + + P I ++ + I E ANI ++L ++ YF I N I K LDYE+ ++ I V + N++ I +VNE P ++ + N + E S G L + L A DP+ ++ F + S N Y I+ + I+LN K + L E+ V+D N + +TI N ++ F + EN PIG+ + +Q + + + ++ SD F + + ++ + +++YET+ +TV + N + L I V D++E P E+ +I ++ E T K IG + D ++N I ++K + CVT PL NC + F+ N Sbjct: 508 MYCGQPNYPPTDILIDNTK-----VEEETSNNECFANLGTKDLNGLLDTFVYSLVN----NFENRLQIMGTQLCLNYRPNYEASNNTWL---VKIKTTDSGNLSFQKSINISVTDINEPPTSCSFDRVNKIPENVGYGYFVGYLTLLDED--KNFRQFKETIFD--------SDSNTFEVFYNSTQLVFKYGIRVSKNETADCLRKGGA-FCSLNYETLNIHKITVKTVDLGTPSYTVYFDLYIQLVDMNDAPTLIVLDNISIPESLNIGDKIGSFHTFDEDNRTQIFIYEILQGNSDYFIIDQNNLLLRQKVDYEDSSQQSLRITVKSTDNGIPPMNVSTEFILKTQNVNEPP--FVSFVSNSIKQEDIYFISIEENNKIGDKLATVYVTDPDINDTVSFFI-KSPNNTIFFNNTQCK---------TNTLKVSSTNCILDLYTKVVFHHETKNNLSFTLISVDKHFLNSATNFFLKIKKIPEIPKNIRFVETDSQIIEIDENIYGANI-SLLTADNVDLLSNLKFTIIQDEGGYFEIINDRILKLKENKCLDYESDSRKNIITVKIADATANLT----IMARNVNEFPSDIILDNTKIFENSTTGTLFSTLDAFDPDLNKTFTFQIISSSNSAFKIYGNEIKIITTNEIYLNFEKKPFETL--------EILVTDRGLLNFTAIFNITILDCNDMPKNL-FLPNSYVTENVPIGTIIGTLQ-SSDEDSNQTVRYQLLSDFITFTLSTNGTIMTSSNINYETSKLYNLTVLYYDNGVPPLTSTGAVIIYVNDLNEPPYFEMEESIALNVPEN--TLKLIGPFQVYDNDLNEILSMKLI-------------CVT-PLNCNCPIKIESFLCEN 1314
BLAST of Protocadherin Fat 4 vs. Planmine SMEST
Match: SMESG000022173.1 (SMESG000022173.1) HSP 1 Score: 82.4185 bits (202), Expect = 3.500e-15 Identity = 59/160 (36.88%), Postives = 81/160 (50.62%), Query Frame = 1 Query: 5179 CHFNSNKCHRNATCKSNE-LNDE---FQCFCNPGFVGNGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHGI-CRDDNS---CLCLSGWEGIDCNKSIDDC-IGDPCNGRGVCEDALNGFICNCQQNFTGIFCEF 5631 C FN C N ++E + D+ F+C C PGF G +E DEC CL + CID + F C+C SG C+V K N C K C++G C D + C C +GW G CN++I++C I PC G+C D + C CQ ++G FC Sbjct: 354 CQFNQTSCDDNPCVGNSECITDKTSGFKCKCPPGFTGRNCEIDE-DECSSKPCL-NGGMCIDRPSGFLCVCPVGFSGDRCQVNK-NDCQKLSCMNGAKCMDRANRIDCECTTGWTGRMCNQNINECAINQPCLNNGICIDTPGSYRCQCQATWSGQFCNL 510 HSP 2 Score: 55.0694 bits (131), Expect = 6.297e-7 Identity = 40/114 (35.09%), Postives = 52/114 (45.61%), Query Frame = 1 Query: 5374 LCGSDRSGRTCEVLKVNLCLKSDCVHGICRDDNSCLCLSGWEGIDCNKSIDDCIGDPCNGRGVCE-----DALNGFICNCQQNFTGIFCEFDHFSCK---NCSENFGVCLNLKN 5691 +C + SG C+ + +CLK C++G C N C C +GW G C D CI P G C L CNC++ + G+FC D C N EN G CLN N Sbjct: 211 ICHTGYSGSYCDKV---VCLKK-CINGACVGPNQCRCQTGWTGDSC----DQCIPYPGCVHGSCRFDETTKELLPLTCNCKKKWGGMFCNIDLNYCSNNPNVCENGGECLNFGN 316 HSP 3 Score: 53.5286 bits (127), Expect = 2.091e-6 Identity = 44/149 (29.53%), Postives = 67/149 (44.97%), Query Frame = 1 Query: 5206 RNATCKSNELNDEFQCFCNPGFVG-----NGSSCEEIDECLFNFCLGDSSRCIDLVNDFQCLCGSDRSGRTCEVLKVNLCLKSDCVHG-ICRDDNS---CLCLSGWEGIDCNKSIDDCIGDPCNGRGVCEDALNGFICNCQQNFTGIFC 5625 + CK N +++ C C F G N +SC++ N C+G+S D + F+C C +GR CE+ + + C C++G +C D S C+C G+ G C + +DC C C D N C C +TG C Sbjct: 328 KPGKCKINVNTNKYICDCPESFYGDRCQFNQTSCDD------NPCVGNSECITDKTSGFKCKCPPGFTGRNCEIDE-DECSSKPCLNGGMCIDRPSGFLCVCPVGFSGDRCQVNKNDCQKLSCMNGAKCMDRANRIDCECTTGWTGRMC 469 The following BLAST results are available for this feature:
BLAST of Protocadherin Fat 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin Fat 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin Fat 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin Fat 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin Fat 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin Fat 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin Fat 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin Fat 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin Fat 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin Fat 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin Fat 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin Fat 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin Fat 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin Fat 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30027114 ID=SMED30027114|Name=Protocadherin Fat 4|organism=Schmidtea mediterranea sexual|type=transcript|length=6232bpback to top protein sequence of SMED30027114-orf-1 >SMED30027114-orf-1 ID=SMED30027114-orf-1|Name=SMED30027114-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2006bp MCWEYSISCPLNFESKTNNISLEILAKDLDVPKNSKLFIIHVAILDANDPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01 |