G_PROTEIN_RECEP_F1_2 domain-containing protein

Overview
NameG_PROTEIN_RECEP_F1_2 domain-containing protein
Smed IDSMED30027057
Length (bp)1328
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30027057) t-SNE clustered cells

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30027057) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30027057) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30027057) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30027057

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30027057h1SMcG0001584 dd_Smed_v4_12500_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30027057h1SMcG0001584 dd_Smed_v4_12500_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30027057h1SMcG0001584 dd_Smed_v4_12500_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: TRHR (thyrotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:12299])

HSP 1 Score: 54.299 bits (129), Expect = 2.693e-7
Identity = 45/147 (30.61%), Postives = 68/147 (46.26%), Query Frame = 2
Query:  116 MLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLI------GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            M N T   L+  +L     P  +    Y  +  LL+      G +GNI   ++ +  K  R  ++  YL +L++ D +VLV   + ++  S +   V  Y  C     L       S   + AFTIER++AIC+P K Q LCT  RA
Sbjct:    1 MENETVSELNQTQLQ----PRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNC-YLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRA 142          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: TRHR (thyrotropin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:12299])

HSP 1 Score: 54.299 bits (129), Expect = 2.693e-7
Identity = 45/147 (30.61%), Postives = 68/147 (46.26%), Query Frame = 2
Query:  116 MLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLI------GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            M N T   L+  +L     P  +    Y  +  LL+      G +GNI   ++ +  K  R  ++  YL +L++ D +VLV   + ++  S +   V  Y  C     L       S   + AFTIER++AIC+P K Q LCT  RA
Sbjct:    1 MENETVSELNQTQLQ----PRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNC-YLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRA 142          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: trhr-1 (Thyrotropin-Releasing Hormone Receptor [Source:UniProtKB/TrEMBL;Acc:Q95YD7])

HSP 1 Score: 57.7658 bits (138), Expect = 7.382e-9
Identity = 49/157 (31.21%), Postives = 83/157 (52.87%), Query Frame = 2
Query:  218 LIGYIGNIFSFIIWIEPKMRR-ENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLST----CSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFM--WIYNERFDSCVFNQLETNGTDFQ 667
            +IG +GN+   +I +  K+R  +  +  YL +L+ +D L     M  ++ Y    N   Y F S+  VL T     +   S + +LAFTIER+  IC P+K +++CT KRA  +   +++F + Y+ Y  F+   I ++   SC F +LE N   ++
Sbjct:   44 VIGVLGNLL--VITVVLKVRGMKTPTNCYLVSLAASDTLFFFASMPHEMMYLLGPND-HYLFGSLGCVLLTYLPYLAMNTSSLSILAFTIERYYGICNPYKARTMCTVKRATCIICGIWIFSMLYHSYWLFLATLIKDDIGTSCSF-RLERNSHAYK 196          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-18 (FLP-2 receptor; FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:G5EEB1])

HSP 1 Score: 56.9954 bits (136), Expect = 1.465e-8
Identity = 47/138 (34.06%), Postives = 71/138 (51.45%), Query Frame = 2
Query:  206 LIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVL-----VFVM------IQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA------IIVSFTLYLFV 568
            L+ +L+G  GN  SFI++  P MR  +S  + L ALS  DF +L     +FV+        DL  S     +      I +++ TCS      +++  T+ERWVA+C P + +  CTP+++      IIVS  LY FV
Sbjct:   12 LVIVLVGIFGNSLSFILFSRPHMR-SSSVNVLLCALSFFDFSLLTLSIPIFVIPNLDLWANDLSLSTYMAYILKLIYPINLMMQTCSVY----IMVMITLERWVAVCRPLQVRVWCTPRKSRNAILVIIVSAFLYNFV 144          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-18 (FLP-2 receptor; FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:G5EEB1])

HSP 1 Score: 56.6102 bits (135), Expect = 1.658e-8
Identity = 47/138 (34.06%), Postives = 71/138 (51.45%), Query Frame = 2
Query:  206 LIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVL-----VFVM------IQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA------IIVSFTLYLFV 568
            L+ +L+G  GN  SFI++  P MR  +S  + L ALS  DF +L     +FV+        DL  S     +      I +++ TCS      +++  T+ERWVA+C P + +  CTP+++      IIVS  LY FV
Sbjct:   12 LVIVLVGIFGNSLSFILFSRPHMR-SSSVNVLLCALSFFDFSLLTLSIPIFVIPNLDLWANDLSLSTYMAYILKLIYPINLMMQTCSVY----IMVMITLERWVAVCRPLQVRVWCTPRKSRNAILVIIVSAFLYNFV 144          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: nmur-3 (NMUR (NeuroMedin U Receptor) homolog [Source:UniProtKB/TrEMBL;Acc:Q7JNX1])

HSP 1 Score: 56.225 bits (134), Expect = 2.091e-8
Identity = 74/287 (25.78%), Postives = 129/287 (44.95%), Query Frame = 2
Query:   83 IDDVFTKIIKNMLNLTAQSLSSIELNLMFSPNRIYIDRY-----MTLIWL---LIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKN--VLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLET--------NGTDFQKQYIFATEIVFSGCVPLLIL---GFNILV-IKEMYRITKCN------RTKSMGNCPQFHDPNQRFNNERSFLFT 859
            I   F   ++ + ++T +SL         S N++ +DR      +TLI++   L+G IGN+ + I+  +      +++  +LA L+ +DF ++V  +  DL   WN    +  + +CS+     +     S + ++  T ER+ AICYPF  +++   KR       ++   L  +I+ G M+    + D C FN+  T           D   +Y F + I  +  +PL  +    F ILV + EM   T  +      R+ S G  P  H  N   +N +SF  T
Sbjct:   34 IKHCFHPDVQFLAHMTLKSLDHPGEQFNNSSNQLLLDRAFLNPILTLIFVFVGLVGLIGNLLTVIVIFKTNSLHSHTN-YFLANLATSDFCLIVVGVSFDLVNIWNDEEPLDIFGYCSLTSTFISLFTFASILTIVLLTAERFTAICYPFSHRTIFDEKRVKRFILLIWFVALLPSIFIGSMFKRVSQ-DFCGFNRQMTYIGRCDLVTSPDSFFRYPFESAITITFVLPLFFIIYCYFRILVTLNEMSNSTHVHTPVGTARSDS-GAFPFPHTSNN--SNTQSFPLT 315          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: frpr-18 (FLP-2 receptor; FMRFamide Peptide Receptor family [Source:UniProtKB/TrEMBL;Acc:G5EEB1])

HSP 1 Score: 55.8398 bits (133), Expect = 2.851e-8
Identity = 47/138 (34.06%), Postives = 71/138 (51.45%), Query Frame = 2
Query:  206 LIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVL-----VFVM------IQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA------IIVSFTLYLFV 568
            L+ +L+G  GN  SFI++  P MR  +S  + L ALS  DF +L     +FV+        DL  S     +      I +++ TCS      +++  T+ERWVA+C P + +  CTP+++      IIVS  LY FV
Sbjct:   12 LVIVLVGIFGNSLSFILFSRPHMR-SSSVNVLLCALSFFDFSLLTLSIPIFVIPNLDLWANDLSLSTYMAYILKLIYPINLMMQTCS----VYIMVMITLERWVAVCRPLQVRVWCTPRKSRNAILVIIVSAFLYNFV 144          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: CNMaR (gene:FBgn0053696 transcript:FBtr0091684)

HSP 1 Score: 73.1738 bits (178), Expect = 1.439e-13
Identity = 47/130 (36.15%), Postives = 73/130 (56.15%), Query Frame = 2
Query:  185 YIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS----WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYL 562
            ++ +Y   +    G IGNI S  ++   K+R+  SS+ YLAAL+++D   L  +  Q L +     +N+N     FC  +   S  +   S   V+AFT+ER++A+ YP KRQ++CT +RA IV F L L
Sbjct:   60 FVHQYYIPVLCCTGSIGNILSVFVFFRTKLRKL-SSSFYLAALAVSDTCFLAGLFAQWLNFLNVDIYNQNY----FCQFFTFFSYLASFCSVWFVVAFTVERFIAVIYPLKRQTMCTVRRAKIVLFCLTL 184          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: PK2-R1 (gene:FBgn0038140 transcript:FBtr0082745)

HSP 1 Score: 60.4622 bits (145), Expect = 1.752e-9
Identity = 73/302 (24.17%), Postives = 137/302 (45.36%), Query Frame = 2
Query:   86 DDVFTKIIKNMLNLTAQSLSSIELNLMFSPNRIY---------IDRYMTL---------IWLLIGYIGNIFSFIIWIEPKMRREN----SSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRY--SFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYL--FVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATE--IVFSG-----CVPLLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTIMLLAVSFYL 892
            +D F   + ++LN+T ++LS    NL+ S N            +D  +TL         +  + G +GN+ + I+     + R N    ++  YL  L+++D ++LV  + Q+L   W  ++  +  + C +  VLS  +   + + + AFT+ER++AIC+PF++ ++    RAI   F ++L  F+L       F  +Y     SC          DF   ++FA    I F G     CV  +++G             K  R++ + + P+      R  N +  +   ++ +AV+F+L
Sbjct:   61 NDKFLTHVAHLLNITTENLS----NLLGSTNGTNASTMAADSPVDESLTLRTALTVCYALIFVAGVLGNLITCIV-----ISRNNFMHTATNFYLFNLAVSDLILLVSGIPQELYNLWYPDMYPFTDAMCIMGSVLSEMAANATVLTITAFTVERYIAICHPFRQHTMSKLSRAIKFIFAIWLAAFLLALPQAMQFSVVYQNEGYSCTMEN------DFYA-HVFAVSGFIFFGGPMTAICVLYVLIG------------VKLKRSRLLQSLPRRTFDANRGLNAQGRVIRMLVAVAVAFFL 334          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: PK1-R (gene:FBgn0038201 transcript:FBtr0305681)

HSP 1 Score: 57.7658 bits (138), Expect = 1.024e-8
Identity = 38/118 (32.20%), Postives = 69/118 (58.47%), Query Frame = 2
Query:  200 MTLIWLLI---GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKN--VLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAI 538
            +T+++ LI   G +GNI + I+ I+       ++  YL +L+++DFL+L+  + Q++ Y W+K   V     C    +L+  S   + + + AFT+ER++AIC+PF  Q++    RAI
Sbjct:   23 VTVVYSLIFITGVVGNISTCIV-IKKNRSMHTATNYYLFSLAISDFLLLLSGVPQEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAI 139          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: PK1-R (gene:FBgn0038201 transcript:FBtr0100131)

HSP 1 Score: 57.7658 bits (138), Expect = 1.024e-8
Identity = 38/118 (32.20%), Postives = 69/118 (58.47%), Query Frame = 2
Query:  200 MTLIWLLI---GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKN--VLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAI 538
            +T+++ LI   G +GNI + I+ I+       ++  YL +L+++DFL+L+  + Q++ Y W+K   V     C    +L+  S   + + + AFT+ER++AIC+PF  Q++    RAI
Sbjct:   23 VTVVYSLIFITGVVGNISTCIV-IKKNRSMHTATNYYLFSLAISDFLLLLSGVPQEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAI 139          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: ETHR (gene:FBgn0038874 transcript:FBtr0084054)

HSP 1 Score: 56.6102 bits (135), Expect = 2.723e-8
Identity = 38/119 (31.93%), Postives = 61/119 (51.26%), Query Frame = 2
Query:  206 LIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVL------VFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIV 544
            ++ +L+G +GN+   I+ ++ K  R NS+ I+L  LS+ D LVL      V V +     +W   VL +  C     +       S + +LA + ER+ AIC P K   +CT  RAI++
Sbjct:   18 IVIMLLGVVGNVMVPIVIVKTKDMR-NSTNIFLTNLSIADLLVLLVCTPTVLVEVNTRPETW---VLGHEMCKAVPFVELTVAHASVLTILAISFERYYAICEPLKAGYVCTKGRAILI 132          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: trhrb (thyrotropin-releasing hormone receptor b [Source:ZFIN;Acc:ZDB-GENE-060503-382])

HSP 1 Score: 54.6842 bits (130), Expect = 1.010e-7
Identity = 38/130 (29.23%), Postives = 64/130 (49.23%), Query Frame = 2
Query:  221 IGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIY 607
            +G +GN+   ++ +  K  R  ++  YL +L++ D +VLV   +  +  S +   V  ++ C             S   + AFTIER++AIC+P K Q LCT  RA  +   +++F   Y +    MW Y
Sbjct:   35 LGIVGNVMVILVVLTTKHMRTPTNG-YLVSLAVADLMVLVAAGLPSIADSLFGSWVFGHAGCLCITYFQYLGINASSCSITAFTIERYIAICHPIKAQFLCTLSRAKKIIIGVWVFTSLYCV----MWFY 159          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: trhr2 (thyrotropin releasing hormone receptor 2 [Source:ZFIN;Acc:ZDB-GENE-050419-193])

HSP 1 Score: 54.6842 bits (130), Expect = 1.252e-7
Identity = 37/138 (26.81%), Postives = 71/138 (51.45%), Query Frame = 2
Query:  197 YMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMI----QDLQYSWNKNVLRYSFC-------SIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCY 577
            ++ L+   +G +GNI   ++ +  +  R  ++  YL +L++ D +VLV   +    + L  SW   V  ++ C        + +  S+CS       + AFT+ER++AIC+P + Q++CT  RA  +   +++F   Y
Sbjct:   36 FLVLLVCGVGIVGNIMVVLVVLTTRHMRTPTNC-YLVSLAVADLMVLVAAGLPNISESLMASW---VYGHAGCLGITYFQYLGINASSCS-------ITAFTVERYIAICHPMRAQTVCTVSRAKRIIAVVWVFTCVY 162          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: trhr2 (thyrotropin releasing hormone receptor 2 [Source:ZFIN;Acc:ZDB-GENE-050419-193])

HSP 1 Score: 53.5286 bits (127), Expect = 2.958e-7
Identity = 35/135 (25.93%), Postives = 70/135 (51.85%), Query Frame = 2
Query:  197 YMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKN-VLRYSFC-------SIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCY 577
            ++ L+   +G +GNI   ++ +  +  R  ++  YL +L++ D +VLV   + ++  S     V  ++ C        + +  S+CS       + AFT+ER++AIC+P + Q++CT  RA  +   +++F   Y
Sbjct:   36 FLVLLVCGVGIVGNIMVVLVVLTTRHMRTPTNC-YLVSLAVADLMVLVAAGLPNISESLMATWVYGHAGCLGITYFQYLGINASSCS-------ITAFTVERYIAICHPMRAQTVCTVSRAKRIIAVVWVFTCVY 162          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: trhr2 (thyrotropin releasing hormone receptor 2 [Source:ZFIN;Acc:ZDB-GENE-050419-193])

HSP 1 Score: 53.5286 bits (127), Expect = 3.014e-7
Identity = 36/138 (26.09%), Postives = 71/138 (51.45%), Query Frame = 2
Query:  197 YMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMI----QDLQYSWNKNVLRYSFC-------SIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCY 577
            ++ L+   +G +GNI   ++ +  +  R  ++  YL +L++ D +VLV   +    + L  +W   V  ++ C        + +  S+CS       + AFT+ER++AIC+P + Q++CT  RA  +   +++F   Y
Sbjct:   37 FLVLLVCGVGIVGNIMVVLVVLTTRHMRTPTNC-YLVSLAVADLMVLVAAGLPNISESLMATW---VYGHAGCLGITYFQYLGINASSCS-------ITAFTVERYIAICHPMRAQTVCTVSRAKRIIAVVWVFTCVY 163          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: gpr139 (G protein-coupled receptor 139 [Source:NCBI gene;Acc:798482])

HSP 1 Score: 51.9878 bits (123), Expect = 6.966e-7
Identity = 38/126 (30.16%), Postives = 61/126 (48.41%), Query Frame = 2
Query:  215 LLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQD-----------LQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLY 559
            L +G   NI + II  +  +RR+ SS  YL AL++ D LVL+ ++  D           L +S NK V    F SI+          S  + +  TI+R++A+C+P +  ++  P R   V   +Y
Sbjct:   36 LCLGLPANILTVIILSQLVLRRQKSSYNYLLALAVADILVLLLIVFVDFLLEDFILGAPLPHSLNKAVQVLEFSSIHT---------SIWITVPLTIDRYIAVCHPLRYHTVSYPARTRKVILAVY 152          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: tmem183a (transmembrane protein 183A [Source:Xenbase;Acc:XB-GENE-944033])

HSP 1 Score: 56.225 bits (134), Expect = 4.102e-8
Identity = 80/333 (24.02%), Postives = 151/333 (45.35%), Query Frame = 2
Query:  224 GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKN---VLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYL--FVLCYNIYNGFMWIYN------ERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPL-LILGFNILVIK---EMYRITKCNRTKSMGNCPQFHDPNQRFNN----ERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYA--LNFVIYLITGKAFRKQFIDKIRKIITKFKLTD 1159
            G +GNI   I  I  + RR+    IY+  L++ D + ++ +    L + W +    V     C+I   L TC+Q     ++ A +++R++A+  PF+  SL T  + I V+  L+   F++ + +     W+Y+      +  +SC F+    N   +   Y+  T   F    PL LIL   IL++    EMY     ++ KS G          R+NN    +R    T ++L+ V  Y+  ++ P    + + Q++     N+ +S+    P   FY       +    +C+S+ +  +N  +Y++    FRK+  D  +   TK ++++
Sbjct:   48 GLVGNILVLITII--RSRRKTIPDIYICNLAVADLVHIIGMPF--LIHQWARGGEWVFGSPLCTIITSLDTCNQFACTAIMTAMSLDRYMALVQPFRLTSLRTISKTIRVNVLLWAASFIVVFPV-----WVYSKVIQFKDGLESCAFDLTTPNDVLWYTLYLTITTFFF----PLPLILACYILILCYTWEMY-----HQNKSAG----------RYNNSIPRQRVLRLTKMVLVLVGVYI-VSSAP----YHVIQIV-----NLQISQ----PSLTFYV------SYYCSICLSYASSGINPFLYVLLSGNFRKRLSDCTK---TKIRMSE 329          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: kiaa1324l (KIAA1324-like [Source:Xenbase;Acc:XB-GENE-5954588])

HSP 1 Score: 53.9138 bits (128), Expect = 2.531e-7
Identity = 35/106 (33.02%), Postives = 56/106 (52.83%), Query Frame = 2
Query:  221 IGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            +G +GNI   ++ ++ K  R  ++  YL +L++ D +VLV   + ++  S +   V  Y  C     L       S   + AFT+ER++AIC+P K Q LCT  RA
Sbjct:   38 LGIVGNIMVVLVVLQTKHMRTPTNC-YLVSLAIADLIVLVAAGLPNITESVYGSWVYGYIGCLCITYLQYLGINASSCSITAFTVERYLAICHPIKAQFLCTISRA 142          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Trhr (thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824])

HSP 1 Score: 53.5286 bits (127), Expect = 3.104e-7
Identity = 36/106 (33.96%), Postives = 55/106 (51.89%), Query Frame = 2
Query:  221 IGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            +G +GNI   ++ +  K  R  ++  YL +L++ D +VLV   + ++  S +   V  Y  C     L       S   + AFTIER++AIC+P K Q LCT  RA
Sbjct:   38 LGIVGNIMVVLVVMRTKHMRTPTNC-YLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRA 142          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Trhr (thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824])

HSP 1 Score: 53.5286 bits (127), Expect = 3.104e-7
Identity = 36/106 (33.96%), Postives = 55/106 (51.89%), Query Frame = 2
Query:  221 IGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            +G +GNI   ++ +  K  R  ++  YL +L++ D +VLV   + ++  S +   V  Y  C     L       S   + AFTIER++AIC+P K Q LCT  RA
Sbjct:   38 LGIVGNIMVVLVVMRTKHMRTPTNC-YLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRA 142          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Trhr (thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824])

HSP 1 Score: 53.5286 bits (127), Expect = 3.104e-7
Identity = 36/106 (33.96%), Postives = 55/106 (51.89%), Query Frame = 2
Query:  221 IGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            +G +GNI   ++ +  K  R  ++  YL +L++ D +VLV   + ++  S +   V  Y  C     L       S   + AFTIER++AIC+P K Q LCT  RA
Sbjct:   38 LGIVGNIMVVLVVMRTKHMRTPTNC-YLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRA 142          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Mtnr1a (melatonin receptor 1A [Source:MGI Symbol;Acc:MGI:102967])

HSP 1 Score: 49.2914 bits (116), Expect = 5.422e-6
Identity = 82/350 (23.43%), Postives = 142/350 (40.57%), Query Frame = 2
Query:  215 LLIGYIGNIFSFI-IWIEPKMRRENSSAIYLAALSLNDFLVLVF----VMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCY---NIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFRKQFIDKIRKIITKFKLTDNFF---SNELVSLNKTNRMELTRENSL 1231
            +++  +GN+   + ++   K+R  NS  I++ +L++ D +V V+    V+   L   WN   L     +  M LS    +F+   +    + R+  IC+  K   + + K ++   F +++  L     N+  G +  Y+ R  SC F Q           Y  A  +VF   VP++I+ F  L I  +  + +  R     N P+     Q F N     F T+ ++ V F          I +A   +I +   +   + +P  P+W F             L   +  LN +IY +  + FRK++    +KII        FF   SNE     K     L   N+L
Sbjct:   41 IVVDILGNLLVILSVYRNKKLR--NSGNIFVVSLAVADLVVAVYPYPLVLTSILNNGWNLGYLHCQVSAFLMGLSVIGSIFN---ITGIAMNRYCYICHSLKYDKIYSNKNSLCYVFLIWMLTLIAIMPNLQTGTLQ-YDPRIYSCTFTQ------SVSSAYTIAV-VVFHFIVPMIIVIFCYLRIWVL--VLQVRRRVKPDNKPKLKP--QDFRN-----FVTMFVVFVLF---------AICWAPLNLIGLIVASDPATMVPRIPEWLFVASY--------YLAYFNSCLNAIIYGLLNQNFRKEY----KKIIVSLCTAKMFFVESSNEEADKIKCKPSPLIPNNNL 347          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8ITC9|PK1R_DROME (Pyrokinin-1 receptor OS=Drosophila melanogaster OX=7227 GN=PK1-R PE=2 SV=1)

HSP 1 Score: 57.7658 bits (138), Expect = 1.026e-7
Identity = 38/118 (32.20%), Postives = 69/118 (58.47%), Query Frame = 2
Query:  200 MTLIWLLI---GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKN--VLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAI 538
            +T+++ LI   G +GNI + I+ I+       ++  YL +L+++DFL+L+  + Q++ Y W+K   V     C    +L+  S   + + + AFT+ER++AIC+PF  Q++    RAI
Sbjct:   23 VTVVYSLIFITGVVGNISTCIV-IKKNRSMHTATNYYLFSLAISDFLLLLSGVPQEVSYIWSKYPYVFGEYICIGRGLLAETSANATVLTITAFTVERYIAICHPFLGQAMSKLSRAI 139          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|O93603|TRFR_CHICK (Thyrotropin-releasing hormone receptor OS=Gallus gallus OX=9031 GN=TRHR PE=2 SV=1)

HSP 1 Score: 55.0694 bits (131), Expect = 7.155e-7
Identity = 42/133 (31.58%), Postives = 63/133 (47.37%), Query Frame = 2
Query:  158 NLMFSPNRIYIDRYMTLIWLLI------GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKN-VLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
             L+ S        Y  +  LL+      G +GNI   ++ +  K  R  ++  YL +L++ D +VLV   + ++  S  K+ V  Y  C     L       S   + AFTIER++AIC+P K Q LCT  RA
Sbjct:   13 GLLLSSQEFVTAEYQVVTILLVLLICGLGIVGNIMVVLVVLRTKHMRTPTNC-YLVSLAVADLMVLVAAGLPNITESLYKSWVYGYVGCLCITYLQYLGINASSFSITAFTIERYIAICHPIKAQFLCTFSRA 144          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q28596|TRFR_SHEEP (Thyrotropin-releasing hormone receptor OS=Ovis aries OX=9940 GN=TRHR PE=2 SV=1)

HSP 1 Score: 54.6842 bits (130), Expect = 8.607e-7
Identity = 45/147 (30.61%), Postives = 68/147 (46.26%), Query Frame = 2
Query:  116 MLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLI------GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            M N T   L+  +L     P  +    Y  +  LL+      G +GNI   ++ +  K  R  ++  YL +L++ D +VLV   + ++  S +   V  Y  C     L       S   + AFTIER++AIC+P K Q LCT  RA
Sbjct:    1 MENETGSELNQTQLQ----PRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNC-YLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRA 142          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|O46639|TRFR_BOVIN (Thyrotropin-releasing hormone receptor OS=Bos taurus OX=9913 GN=TRHR PE=3 SV=1)

HSP 1 Score: 54.6842 bits (130), Expect = 9.829e-7
Identity = 45/147 (30.61%), Postives = 68/147 (46.26%), Query Frame = 2
Query:  116 MLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLI------GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            M N T   L+  +L     P  +    Y  +  LL+      G +GNI   ++ +  K  R  ++  YL +L++ D +VLV   + ++  S +   V  Y  C     L       S   + AFTIER++AIC+P K Q LCT  RA
Sbjct:    1 MENETGSELNQTQLQ----PRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNC-YLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRA 142          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|P34981|TRFR_HUMAN (Thyrotropin-releasing hormone receptor OS=Homo sapiens OX=9606 GN=TRHR PE=1 SV=1)

HSP 1 Score: 54.299 bits (129), Expect = 1.293e-6
Identity = 45/147 (30.61%), Postives = 68/147 (46.26%), Query Frame = 2
Query:  116 MLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLI------GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            M N T   L+  +L     P  +    Y  +  LL+      G +GNI   ++ +  K  R  ++  YL +L++ D +VLV   + ++  S +   V  Y  C     L       S   + AFTIER++AIC+P K Q LCT  RA
Sbjct:    1 MENETVSELNQTQLQ----PRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNC-YLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRA 142          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A267FQY4 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012459g3 PE=4 SV=1)

HSP 1 Score: 236.884 bits (603), Expect = 2.072e-69
Identity = 130/345 (37.68%), Postives = 188/345 (54.49%), Query Frame = 2
Query:  167 FSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFM----WIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMG-NCPQFHDPNQ-----------------RFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFRKQFIDKIRKI 1135
            F PN +  DR +T IW ++G  GN  S I+W+ P++RR NSSA+YLAALSL D   L+    Q+L+ +WN +      CS   VL   +Q  SP+LVL FT+ERWV++C+PF+R+SLCTP+RA  V   + + V+ +N++  +      +  ER+                  Y   TE+V SG VP   L FN++V++E+ RI   +     G   P   D                      N ER F  TT+ LL VSF++  TTLP G+++ LQ        NM   ++ +DP WQ +F ++ +K VIDE+ +SHY+LNF+IYL TG  FR +  D  R+I
Sbjct:   26 FIPNVMRFDRVVTPIWYVLGLFGNTLSAIVWLSPEVRRNNSSAVYLAALSLWDLAFLLLHTFQELKEAWNISTQNTFTCSCLPVLLLTAQYLSPLLVLGFTVERWVSVCFPFRRESLCTPRRACSVVGAMTVGVVLWNLWQLYFKTGCEVAEERYG--------------WTAYTVGTEVVISGLVPAAALVFNLMVLREIRRINSASAAHKFGAAAPSAADNGGGADQCGNASRDAGGGGAGGNTERKFRTTTVTLLCVSFFVILTTLPAGMVYGLQSYANFGSINMTDEEVLADPVWQRHFAMTRVKKVIDEVSLSHYSLNFLIYLATGMQFRLRVADIFRRI 356          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A267DSG4 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012459g1 PE=4 SV=1)

HSP 1 Score: 234.572 bits (597), Expect = 1.650e-68
Identity = 128/340 (37.65%), Postives = 185/340 (54.41%), Query Frame = 2
Query:  167 FSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFM----WIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMG-NCPQFHDPNQR-----------------FNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFRKQFID 1120
            F PN +  DR +T IW ++G  GN  S I+W+ P++RR NSSA+YLAALSL D   L+    Q+L+ +WN +      CS   VL   +Q  SP+LVL FT+ERWV++C+PF+R+SLCTP+RA  V   + + V+ +N++  +      +  ER+                  Y   TE+V SG VP   L FN++V++E+ RI   +     G   P   D                      N ER F  TT+ LL VSF++  TTLP G+++ LQ        NM   ++ +DP WQ +F ++ +K VIDE+ +SHY+LNF+IYL TG  FR +  D
Sbjct:   26 FIPNVMRFDRVVTPIWYVLGLFGNTLSAIVWLSPEVRRNNSSAVYLAALSLWDLAFLLLHTFQELKEAWNISTQNTFTCSCLPVLLLTAQYLSPLLVLGFTVERWVSVCFPFRRESLCTPRRACSVVGAMTVGVVLWNLWQLYFKTGCEVAEERYG--------------WTAYTVGTEVVISGLVPAAALVFNLMVLREIRRINSASAAHKFGAAAPSAADNGGGAGQCGNASRDAGGGGAGGNTERKFRTTTVTLLCVSFFVILTTLPAGMVYGLQSYANFGSINMTDEEVLADPVWQRHFAMTRVKKVIDEVSLSHYSLNFLIYLATGMQFRLRVAD 351          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A267F7F2 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig007315g1 PE=4 SV=1)

HSP 1 Score: 231.491 bits (589), Expect = 1.147e-67
Identity = 136/335 (40.60%), Postives = 195/335 (58.21%), Query Frame = 2
Query:  122 NLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSW---NKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQV----ITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFR 1105
            NL ++  + + L   F+P+ + +DR +T  W  +G  GN+ S  +W+ P++RR+NSSA+YLAALS+ D + L     Q+++ +W   ++N L    C +  +    +Q  SPVLVL FT+ERW+AI +PFKR SLCTPKRA IV+  +   V  YN+       Y+     C+ N      T     Y   +EI+FSG VP+  L FNILV  E+YRIT  N  K M       D +     ER F  TT+MLL VSF++  T+LP G+++ALQ      +T+ D     S++  D  WQ YF  ++ K ++DEL ISHY+LNFVIYL+TG  +R
Sbjct:   18 NLQSKYKTLVALYARFAPSILIVDRSITPFWYFLGLFGNLLSAYVWMHPRVRRKNSSAVYLAALSVWDLIFLALHPFQEVREAWMGISENSLLD--CGLLHIPLLTAQYMSPVLVLCFTVERWIAIWFPFKRDSLCTPKRACIVTVVMICIVFFYNLIQLKFRRYDYELSVCIVNTQAVEWT----VYTSISEIIFSGFVPISALVFNILVAIELYRITVVN--KHMMPNGDGGDASA----ERKFRSTTLMLLCVSFFVIVTSLPAGLLYALQNQNYGNVTLTD-----SEVEQDSTWQSYFSATLTKKIVDELSISHYSLNFVIYLLTGPQYR 335          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A267FY03 (G_PROTEIN_RECEP_F1_2 domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig012459g2 PE=4 SV=1)

HSP 1 Score: 233.417 bits (594), Expect = 1.160e-67
Identity = 127/340 (37.35%), Postives = 185/340 (54.41%), Query Frame = 2
Query:  167 FSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFM----WIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMG-NCPQFHDPNQ-----------------RFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFRKQFID 1120
            F PN +  DR +T IW ++G  GN  S I+W+ P++RR NSSA+YLAALSL D   L+    Q+L+ +WN +      CS   VL   +Q  SP+LVL FT+ERWV++C+PF+R+ LCTP+RA  V   + + V+ +N++  +      +  ER+                  Y   TE+V SG VP   L FN++V++E+ RI   +  +  G   P   D                      N ER F  TT+ LL VSF++  TTLP G+++ LQ        NM   ++ +DP WQ +F ++ +K VIDE+ +SHY+LNF+IYL TG  FR +  D
Sbjct:   63 FIPNVMRFDRVVTPIWYVLGLFGNTLSAIVWLSPEVRRNNSSAVYLAALSLWDLAFLLLHTFQELKEAWNISTQNTFTCSCLPVLLLTAQYLSPLLVLGFTVERWVSVCFPFRRELLCTPRRACSVVGAMTVGVVLWNLWQLYFKTGCEVAEERYG--------------WTAYTVGTEVVISGLVPAAALVFNLMVLREIRRINSASAARKFGAAAPSVADNGGGAGQCGNASRDAGGGGAGGNTERKFRTTTVTLLCVSFFVILTTLPAGMVYGLQSYANFGSINMTDEEVLADPVWQRHFAMTRVKKVIDEVSLSHYSLNFLIYLATGMQFRLRVAD 388          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A267F1S3 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig007315g2 PE=4 SV=1)

HSP 1 Score: 230.72 bits (587), Expect = 2.604e-67
Identity = 135/335 (40.30%), Postives = 195/335 (58.21%), Query Frame = 2
Query:  122 NLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSW---NKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQV----ITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFR 1105
            NL ++  + + L   F+P+ + +DR +T  W  +G  GN+ S  +W+ P++RR+NSSA+YLAALS+ D + L     Q+++ +W   ++N L    C +  +    +Q  SPVLVL FT+ERW+AI +PFKR SLCTPKRA IV+  +   V  YN+       Y+     C+ N      T     Y   +EI+FSG VP+  L FN+LV  E+YRIT  N  K M       D +     ER F  TT+MLL VSF++  T+LP G+++ALQ      +T+ D     S++  D  WQ YF  ++ K ++DEL ISHY+LNFVIYL+TG  +R
Sbjct:   18 NLQSKYKTLVALYARFAPSILIVDRSITPFWYFLGLFGNLLSAYVWMHPRVRRKNSSAVYLAALSVWDLIFLALHPFQEVREAWMGISENSLLD--CGLLHIPLLTAQYMSPVLVLCFTVERWIAIWFPFKRDSLCTPKRACIVTVAMICIVFFYNLIQLKFRRYDYELSVCIVNTQAVEWT----VYTSISEIIFSGFVPISALVFNLLVAIELYRITVGN--KHMMPNGDGGDASA----ERKFRSTTLMLLCVSFFVIVTSLPAGLLYALQNQNYGNVTLTD-----SEVEQDSTWQSYFSATLTKKIVDELSISHYSLNFVIYLLTGPQYR 335          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: trhr2 (thyrotropin-releasing hormone receptor-like [Source:NCBI gene;Acc:103031192])

HSP 1 Score: 53.5286 bits (127), Expect = 2.498e-7
Identity = 35/131 (26.72%), Postives = 65/131 (49.62%), Query Frame = 2
Query:  197 YMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMI----QDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCY 577
            ++ L+   +G +GNI   ++ +  +  R  ++  YL +L++ D  VLV   +    + L  +W   V  ++ C     L       S   + AFT+ER++AIC+P + Q++CT  RA  +   ++ F   Y
Sbjct:   38 FLVLLVCGVGIVGNIMVVLVVLTTRHMRTPTNC-YLVSLAVADLTVLVAAGLPNISESLMATW---VYGHAGCLGITYLQYLGINVSSCSITAFTVERYIAICHPMRAQTVCTVSRAKRIIAGVWAFTCVY 164          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: TRHR (thyrotropin-releasing hormone receptor [Source:NCBI gene;Acc:103040459])

HSP 1 Score: 52.7582 bits (125), Expect = 4.040e-7
Identity = 34/106 (32.08%), Postives = 56/106 (52.83%), Query Frame = 2
Query:  221 IGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYS-WNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            +G IGN    ++ +  K  R  ++  YL +L++ D +VL    + ++  S + + V  Y+ C     L       S   + AFT+ER++AIC+P + QSLCT  RA
Sbjct:   43 LGIIGNAMVILVVLTTKHMRTPTNC-YLVSLAVADLMVLTAAGLPNITDSLFEQWVYGYAGCLSITYLQYVGINASSCSITAFTVERYIAICHPIRAQSLCTLSRA 147          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: trhrb (thyrotropin-releasing hormone receptor-like [Source:NCBI gene;Acc:103029490])

HSP 1 Score: 50.447 bits (119), Expect = 2.343e-6
Identity = 40/148 (27.03%), Postives = 69/148 (46.62%), Query Frame = 2
Query:  221 IGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVL---RYSFCSIY-----MVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQ 640
            +G +GN+   ++ +  K  R  ++  YL +L+  D +VLV   +  +  S   + L       C  Y     +  S+CS       + AFT+ER++AIC+P + QSLCT  RA  +   +++    Y +    MW Y    +  V+  
Sbjct:   35 LGIVGNVMVILVVLTTKHMRTPTNC-YLVSLAAADLMVLVAAGLPSVADSLYGSWLFGRVGCLCITYFQYLGINASSCS-------ITAFTVERYIAICHPIRAQSLCTYTRAKRIILGVWVTTSLYCV----MWFYLADIEELVYED 170          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000054912.1 (thyrotropin-releasing hormone receptor-like [Source:NCBI gene;Acc:103035526])

HSP 1 Score: 49.2914 bits (116), Expect = 5.373e-6
Identity = 36/140 (25.71%), Postives = 67/140 (47.86%), Query Frame = 2
Query:  188 IDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIY 607
            I  ++TL+   +G  GN+   ++ +  K     ++  YL +L++ D +VL+   + ++       +  Y+ C     L       S   + AFT+ER++AIC+  K Q +CT  RA  +   +++F   Y I    MW +
Sbjct:   31 ITIFLTLLICGVGIAGNVMVVLVVLRTKHMMTPTNC-YLVSLAIADLIVLLAAGLPNISEVVASWIYGYAGCLCITYLQYLGINVSSCSITAFTVERYIAICHSIKAQFICTVSRAKKIIACVWIFTSLYCI----MWFF 165          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000039165.1 (pep primary_assembly:Astyanax_mexicanus-2.0:4:20687738:20691315:1 gene:ENSAMXG00000035985.1 transcript:ENSAMXT00000039165.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.521 bits (114), Expect = 7.833e-6
Identity = 49/203 (24.14%), Postives = 92/203 (45.32%), Query Frame = 2
Query:  200 MTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLV---FVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMGN 799
            + L+  ++G +GN    I+ I    +  +++ +Y+  L+L D L +V   FV  Q+ Q  W    L    C + MVL   +Q  S   +   +++R++A+  P +     TPKRA I+S  L+LF L   +   F   ++ ++D C+ +    N          +   V    +P L++   I+    +    +C R +  G+
Sbjct:   41 LHLVVCIMGLVGNSL-VIVAILKLDKMSSATTVYIFNLALADGLFMVGLPFVAFQNFQNEWIFGDLA---CKLVMVLDGINQFTSVFCLTVMSVDRYMALVDPLRFARWRTPKRAKIISAFLWLFSLLPVLPMAFH--FSVKYDLCMADTFMMN----WWMTFLSITFVVGFALPFLVM---IIFYTALVMTLRCARQRDGGS 230          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Match: trhrb (thyrotropin-releasing hormone receptor b [Source:ZFIN;Acc:ZDB-GENE-060503-382])

HSP 1 Score: 54.6842 bits (130), Expect = 1.967e-8
Identity = 34/105 (32.38%), Postives = 57/105 (54.29%), Query Frame = 2
Query:  224 GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKN-VLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRA 535
            G +GN+   ++ +  K  R  ++  YL +L++ D LVL+   + ++  S  ++ V  Y+ C     L       S   + AFT+ER++AIC+P + QSLCT  RA
Sbjct:   46 GIVGNVMIVLVVVRTKHMRTPTN-YYLGSLAIADLLVLLAAGLPNVSDSLAESWVYGYAGCLAITYLQYLGINVSSCSITAFTLERYLAICHPIRAQSLCTVSRA 149          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr2 (TRHR2 protein [Source:NCBI gene;Acc:100533510])

HSP 1 Score: 52.7582 bits (125), Expect = 4.049e-7
Identity = 34/128 (26.56%), Postives = 63/128 (49.22%), Query Frame = 2
Query:  197 YMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKN-VLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCY 577
            ++ L+   +G IGN+   ++    +  R  ++  YL +L++ D  VLV   + ++  S     +   + C     L       S   + AFT+ER++AIC+P K Q++CT  RA  +   +++F   Y
Sbjct:   35 FLVLLVCGVGIIGNVMVVLVVFTTRHMRTPTNC-YLVSLAIADLTVLVAAGLPNVSDSLTGTWIFGQAGCLGITYLQYLGINVSSCSITAFTVERYIAICHPMKAQTVCTVSRAKRIIAGVWIFTCVY 161          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr2 (TRHR2 protein [Source:NCBI gene;Acc:100533510])

HSP 1 Score: 50.8322 bits (120), Expect = 1.417e-6
Identity = 34/131 (25.95%), Postives = 64/131 (48.85%), Query Frame = 2
Query:  188 IDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKN-VLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCY 577
            +  ++ L+   +G IGN+   ++    +  R  ++  YL +L++ D  VLV   + ++  S     +   + C     L       S   + AFT+ER++AIC+P K Q++CT  RA  +   +++F   Y
Sbjct:   24 VSVFLVLLVCGVGIIGNVMVVLVVFTTRHMRTPTNC-YLVSLAIADLTVLVAAGLPNVSDSLTGTWIFGQAGCLGITYLQYLGINVSSCSITAFTVERYIAICHPMKAQTVCTVSRAKRIIAGVWIFTCVY 153          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr3 (TRHR3 protein [Source:NCBI gene;Acc:100533511])

HSP 1 Score: 49.6766 bits (117), Expect = 3.687e-6
Identity = 40/149 (26.85%), Postives = 68/149 (45.64%), Query Frame = 2
Query:  197 YMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVM---IQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVF 634
            ++TL+   +G  GN+   ++ +  K      +  YL +L++ D +VL+      I D+   W   +  Y+ C     L       S   + AFTIER++AIC+  K Q +CT  RA  +   +++F   Y      MW +    D  V+
Sbjct:   33 FLTLLICGVGIAGNVMVVLVVLRTK-HMVTPTNCYLVSLAVADLIVLLAAGLPNISDVVACW---IYGYTGCLFITYLQYLGINVSSCSITAFTIERYIAICHSIKAQFICTVSRAKRIIAGVWIFTSLYCT----MWFFLVDIDETVY 173          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: trhr1b (TRHR1b protein [Source:NCBI gene;Acc:100533509])

HSP 1 Score: 49.2914 bits (116), Expect = 4.715e-6
Identity = 43/148 (29.05%), Postives = 68/148 (45.95%), Query Frame = 2
Query:  224 GYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVL--RYS-FCSIY-----MVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQL 643
            G +GNI   ++ +  K  R  ++  YL +L++ D +VL    +  +  S     +  RY   C  Y     +  S+CS       + AFTIER++AIC+P K Q LCT  RA  +   ++ F   Y +    MW Y       V+  +
Sbjct:   39 GIVGNIMVILVVLTTKHMRTPTNC-YLVSLAVADLMVLTAAGLPAITDSIFATWVFGRYGCLCITYFQYLGINASSCS-------ITAFTIERYIAICHPIKAQFLCTLSRAKKIILFVWAFTSIYCV----MWFYLSDIQELVYENI 174          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000035391.1 (uncharacterized LOC101165559 [Source:NCBI gene;Acc:101165559])

HSP 1 Score: 47.7506 bits (112), Expect = 7.188e-6
Identity = 34/119 (28.57%), Postives = 67/119 (56.30%), Query Frame = 2
Query:  215 LLIGYIGNIFS-FIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNV--LRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYL 562
            +L G +GNI +  ++W+ P MR  +S+ +YL++++++D L+L+ + +  L   W      L    C + M LS C    + + +   ++ER+VA+C+P   ++L T +R   +   L+L
Sbjct:   61 MLFGLLGNILTILVVWLRPHMR--SSTYLYLSSMAISDLLILLLLPLD-LYKLWRPRPWPLGDLACKLTMFLSECCTFCTILHITFLSLERYVAVCWPITAKTLVTRRRTRAIIGCLWL 176          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000031888.1 (SMESG000031888.1)

HSP 1 Score: 803.512 bits (2074), Expect = 0.000e+0
Identity = 392/393 (99.75%), Postives = 393/393 (100.00%), Query Frame = 2
Query:  116 MLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFRKQFIDKIRKIITKFKLTDNFFSNELVSLNKTNRMELTRENSLDFCHLNDANNSRRNRLTAKVI 1294
            MLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYL+TGKAFRKQFIDKIRKIITKFKLTDNFFSNELVSLNKTNRMELTRENSLDFCHLNDANNSRRNRLTAKVI
Sbjct:    1 MLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLVTGKAFRKQFIDKIRKIITKFKLTDNFFSNELVSLNKTNRMELTRENSLDFCHLNDANNSRRNRLTAKVI 393          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000031888.1 (SMESG000031888.1)

HSP 1 Score: 747.273 bits (1928), Expect = 0.000e+0
Identity = 364/365 (99.73%), Postives = 365/365 (100.00%), Query Frame = 2
Query:  200 MTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFRKQFIDKIRKIITKFKLTDNFFSNELVSLNKTNRMELTRENSLDFCHLNDANNSRRNRLTAKVI 1294
            MTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYL+TGKAFRKQFIDKIRKIITKFKLTDNFFSNELVSLNKTNRMELTRENSLDFCHLNDANNSRRNRLTAKVI
Sbjct:    1 MTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLVTGKAFRKQFIDKIRKIITKFKLTDNFFSNELVSLNKTNRMELTRENSLDFCHLNDANNSRRNRLTAKVI 365          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000014330.1 (SMESG000014330.1)

HSP 1 Score: 187.578 bits (475), Expect = 1.289e-54
Identity = 121/384 (31.51%), Postives = 199/384 (51.82%), Query Frame = 2
Query:  185 YIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYS-FCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFA--TEIVFSGCVPLLILGFNILVIKEMYRITKCNR----------TKSMGNCPQF-----------------HDPNQRFNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFRKQFIDKIRKIITKFKLTDN------FFSNELVSLNKTNRMELTRENS 1228
            Y+ RY +L+WL+ G + N  +FIIW  P++RR N+SA YLA ++++D +  +  ++  +Q SW+  V     +C ++  L   SQ FS  LVL F++ER++A+C+PFKR+ LCT ++A++ +    +  L           YN+    C    +  +  + +  +IFA  TEI+ S  +P   L  NILVI E+  IT              T S     Q                  H  +Q+   + +F  +TI+LL+VSF L  TTLP G ++ALQ V  + +E +++ ++  DP W  +    I+K V+D   + H+++NFVIY ITG++FR +F    +    +FK  D+      +FSN      + N  E+ R+ +
Sbjct:   30 YLHRYGSLLWLMSGLVLNTLAFIIWTRPRLRRSNTSANYLAGIAMSDTIFWLLYILHYMQTSWDICVQDIPVWCEMFQGLFISSQYFSVPLVLIFSLERYIAVCHPFKREKLCTHRKALVNTIVCGVTALILGCSQSISREYNDVSKKC---DIRGSVVNTRNWFIFATGTEILISALLPFATLIVNILVIIELKSITSKTTLIKPSVTAPLTSSTSTSEQHLQIQRNQGSTEKLNIKKHSISQQNKEKSAFKSSTILLLSVSFLLIVTTLPTGFVYALQFVCPVGNETLSVEQMKVDPDWIKFINYQILKEVVDFFSMIHFSINFVIYYITGESFRTEFYLLFQN-AKRFKGPDDTSIGNSYFSNRNGHNQRVNHTEMLRKQA 409          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000018637.1 (SMESG000018637.1)

HSP 1 Score: 186.808 bits (473), Expect = 1.870e-54
Identity = 123/352 (34.94%), Postives = 191/352 (54.26%), Query Frame = 2
Query:  113 NMLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRY-SFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLY--LFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRT--KSMGNCPQFHDPNQR-------FNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENM-NLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFRKQFIDKIR 1129
            N  + T+   + +E+  +F P    +  Y   I+L +G +GN  SF++W+  K+RR NSSA+Y+A L++NDF V++  +I  L++SW   ++     C  YMV+ T  Q  S +LV  FTIERW+A+CYPF+R+  CT  RA I    ++  +F+  + ++  F+W Y      C   +     T F   Y    EI+FS  +P++ L  NI V+ EMYRI++   T  K       F  P+Q+         N  SF  TTI LL VSF+   TTLP G ++  Q  I  P+ N  ++ ++ +DP W+ +F++   K +ID L +SHY  N VIYL +   FR   +  ++
Sbjct:    2 NETSATSNEKTLLEIRQIFLPISYQLQLYSIPIFLTVGILGNPISFVVWVSRKLRRNNSSAVYIAMLAINDFFVVICSIIYYLRHSWGFGIIDIRGICKFYMVIFTFLQYNSILLVFGFTIERWIAVCYPFRRERCCTENRAWIACGIIFSSVFISVFPLF--FVWHYQPL---CSVPKHWIENTYFVT-YSLTLEILFSALLPVITLAVNIRVVVEMYRISETIVTFPKLSAVNQNFEIPSQKSRKHSKNTENSISFKSTTITLLLVSFFQILTTLPLGAVYICQ--IFYPEGNATSVKQMQNDPIWKKHFQMHGAKDIIDLLSLSHYCFNIVIYLASSHLFRNHLMGFVK 345          
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000018637.1 (SMESG000018637.1)

HSP 1 Score: 186.422 bits (472), Expect = 5.713e-54
Identity = 123/352 (34.94%), Postives = 191/352 (54.26%), Query Frame = 2
Query:  113 NMLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIEPKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRY-SFCSIYMVLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLY--LFVLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVPLLILGFNILVIKEMYRITKCNRT--KSMGNCPQFHDPNQR-------FNNERSFLFTTIMLLAVSFYLFFTTLPGGIMFALQQVITMPDENM-NLSKIPSDPKWQFYFRVSIIKAVIDELCISHYALNFVIYLITGKAFRKQFIDKIR 1129
            N  + T+   + +E+  +F P    +  Y   I+L +G +GN  SF++W+  K+RR NSSA+Y+A L++NDF V++  +I  L++SW   ++     C  YMV+ T  Q  S +LV  FTIERW+A+CYPF+R+  CT  RA I    ++  +F+  + ++  F+W Y      C   +     T F   Y    EI+FS  +P++ L  NI V+ EMYRI++   T  K       F  P+Q+         N  SF  TTI LL VSF+   TTLP G ++  Q  I  P+ N  ++ ++ +DP W+ +F++   K +ID L +SHY  N VIYL +   FR   +  ++
Sbjct:   47 NETSATSNEKTLLEIRQIFLPISYQLQLYSIPIFLTVGILGNPISFVVWVSRKLRRNNSSAVYIAMLAINDFFVVICSIIYYLRHSWGFGIIDIRGICKFYMVIFTFLQYNSILLVFGFTIERWIAVCYPFRRERCCTENRAWIACGIIFSSVFISVFPLF--FVWHYQPL---CSVPKHWIENTYFVT-YSLTLEILFSALLPVITLAVNIRVVVEMYRISETIVTFPKLSAVNQNFEIPSQKSRKHSKNTENSISFKSTTITLLLVSFFQILTTLPLGAVYICQ--IFYPEGNATSVKQMQNDPIWKKHFQMHGAKDIIDLLSLSHYCFNIVIYLASSHLFRNHLMGFVK 390          
The following BLAST results are available for this feature:
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
TRHR2.693e-730.61thyrotropin releasing hormone receptor [Source:HGN... [more]
TRHR2.693e-730.61thyrotropin releasing hormone receptor [Source:HGN... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trhr-17.382e-931.21Thyrotropin-Releasing Hormone Receptor [Source:Un... [more]
frpr-181.465e-834.06FLP-2 receptor; FMRFamide Peptide Receptor family ... [more]
frpr-181.658e-834.06FLP-2 receptor; FMRFamide Peptide Receptor family ... [more]
nmur-32.091e-825.78NMUR (NeuroMedin U Receptor) homolog [Source:UniP... [more]
frpr-182.851e-834.06FLP-2 receptor; FMRFamide Peptide Receptor family ... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CNMaR1.439e-1336.15gene:FBgn0053696 transcript:FBtr0091684[more]
PK2-R11.752e-924.17gene:FBgn0038140 transcript:FBtr0082745[more]
PK1-R1.024e-832.20gene:FBgn0038201 transcript:FBtr0305681[more]
PK1-R1.024e-832.20gene:FBgn0038201 transcript:FBtr0100131[more]
ETHR2.723e-831.93gene:FBgn0038874 transcript:FBtr0084054[more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trhrb1.010e-729.23thyrotropin-releasing hormone receptor b [Source:Z... [more]
trhr21.252e-726.81thyrotropin releasing hormone receptor 2 [Source:Z... [more]
trhr22.958e-725.93thyrotropin releasing hormone receptor 2 [Source:Z... [more]
trhr23.014e-726.09thyrotropin releasing hormone receptor 2 [Source:Z... [more]
gpr1396.966e-730.16G protein-coupled receptor 139 [Source:NCBI gene;A... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
tmem183a4.102e-824.02transmembrane protein 183A [Source:Xenbase;Acc:XB-... [more]
kiaa1324l2.531e-733.02KIAA1324-like [Source:Xenbase;Acc:XB-GENE-5954588][more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Trhr3.104e-733.96thyrotropin releasing hormone receptor [Source:MGI... [more]
Trhr3.104e-733.96thyrotropin releasing hormone receptor [Source:MGI... [more]
Trhr3.104e-733.96thyrotropin releasing hormone receptor [Source:MGI... [more]
Mtnr1a5.422e-623.43melatonin receptor 1A [Source:MGI Symbol;Acc:MGI:1... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8ITC9|PK1R_DROME1.026e-732.20Pyrokinin-1 receptor OS=Drosophila melanogaster OX... [more]
sp|O93603|TRFR_CHICK7.155e-731.58Thyrotropin-releasing hormone receptor OS=Gallus g... [more]
sp|Q28596|TRFR_SHEEP8.607e-730.61Thyrotropin-releasing hormone receptor OS=Ovis ari... [more]
sp|O46639|TRFR_BOVIN9.829e-730.61Thyrotropin-releasing hormone receptor OS=Bos taur... [more]
sp|P34981|TRFR_HUMAN1.293e-630.61Thyrotropin-releasing hormone receptor OS=Homo sap... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267FQY42.072e-6937.68G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A267DSG41.650e-6837.65G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A267F7F21.147e-6740.60G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
A0A267FY031.160e-6737.35G_PROTEIN_RECEP_F1_2 domain-containing protein (Fr... [more]
A0A267F1S32.604e-6740.30G_PROTEIN_RECEP_F1_2 domain-containing protein OS=... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trhr22.498e-726.72thyrotropin-releasing hormone receptor-like [Sourc... [more]
TRHR4.040e-732.08thyrotropin-releasing hormone receptor [Source:NCB... [more]
trhrb2.343e-627.03thyrotropin-releasing hormone receptor-like [Sourc... [more]
ENSAMXT00000054912.15.373e-625.71thyrotropin-releasing hormone receptor-like [Sourc... [more]
ENSAMXT00000039165.17.833e-624.14pep primary_assembly:Astyanax_mexicanus-2.0:4:2068... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
trhrb1.967e-832.38thyrotropin-releasing hormone receptor b [Source:Z... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
trhr24.049e-726.56TRHR2 protein [Source:NCBI gene;Acc:100533510][more]
trhr21.417e-625.95TRHR2 protein [Source:NCBI gene;Acc:100533510][more]
trhr33.687e-626.85TRHR3 protein [Source:NCBI gene;Acc:100533511][more]
trhr1b4.715e-629.05TRHR1b protein [Source:NCBI gene;Acc:100533509][more]
ENSORLT00000035391.17.188e-628.57uncharacterized LOC101165559 [Source:NCBI gene;Acc... [more]
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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000031888.10.000e+099.75SMESG000031888.1[more]
SMESG000031888.10.000e+099.73SMESG000031888.1[more]
SMESG000014330.11.289e-5431.51SMESG000014330.1[more]
SMESG000018637.11.870e-5434.94SMESG000018637.1[more]
SMESG000018637.15.713e-5434.94SMESG000018637.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30027057 ID=SMED30027057|Name=G_PROTEIN_RECEP_F1_2 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1328bp
AAATTTAGTTGTAAAACAAATATTGCAACTCAAATAGACAATAGGATGAG
TATTCTTAATTGAAAATGAAACTTTTCACTAAATAGATGATGTTTTCACT
AAGATAATTAAAAACATGCTGAATCTGACCGCACAAAGTTTATCATCAAT
CGAACTAAACCTCATGTTTTCTCCCAACAGGATCTATATAGATAGGTATA
TGACCCTCATATGGCTTCTAATTGGGTATATCGGTAATATTTTTTCTTTT
ATCATTTGGATTGAACCGAAGATGAGAAGAGAAAATTCCTCAGCTATTTA
TCTTGCAGCCTTATCTTTAAATGACTTTTTAGTTTTGGTTTTTGTAATGA
TTCAAGACTTGCAATATTCATGGAACAAGAACGTTTTGCGATATTCATTT
TGTTCGATCTACATGGTGCTGAGTACATGTAGTCAGCTATTCTCTCCAGT
TCTAGTTTTGGCCTTTACCATTGAACGCTGGGTGGCGATCTGCTATCCAT
TCAAAAGACAATCTCTCTGTACACCTAAAAGAGCTATTATCGTCAGTTTT
ACTTTATACCTTTTCGTGCTCTGTTATAATATTTACAATGGGTTTATGTG
GATTTACAATGAAAGATTTGACTCGTGTGTTTTCAATCAACTTGAAACAA
ATGGAACTGACTTTCAAAAGCAATATATTTTCGCTACAGAGATTGTTTTC
AGTGGTTGTGTTCCGTTGTTAATTTTGGGATTTAACATTCTCGTCATTAA
GGAAATGTATCGAATTACTAAGTGTAATCGAACAAAAAGTATGGGAAATT
GTCCACAATTCCACGATCCAAACCAAAGATTCAACAATGAGAGATCTTTT
CTTTTCACAACCATAATGCTGCTAGCCGTGAGCTTTTATTTGTTTTTCAC
TACTCTCCCAGGAGGAATAATGTTTGCTCTTCAACAAGTCATAACAATGC
CTGATGAAAATATGAATTTATCTAAGATCCCTTCCGATCCAAAATGGCAG
TTCTATTTCAGAGTCAGCATCATCAAAGCTGTGATCGACGAATTGTGCAT
TTCTCATTACGCACTCAATTTCGTCATTTATTTAATTACTGGAAAAGCTT
TCCGAAAACAATTCATAGACAAAATCAGAAAAATCATTACCAAATTTAAA
TTAACTGACAACTTTTTCTCCAATGAATTGGTTTCGCTAAACAAAACAAA
TCGAATGGAATTAACCCGCGAAAACAGTTTGGATTTCTGTCATTTAAATG
ATGCTAACAATTCACGTCGGAACAGACTTACAGCAAAAGTTATTTAATCA
ACAAATTTATAACTTTATTCAAATTTTA
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protein sequence of SMED30027057-orf-1

>SMED30027057-orf-1 ID=SMED30027057-orf-1|Name=SMED30027057-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=394bp
MLNLTAQSLSSIELNLMFSPNRIYIDRYMTLIWLLIGYIGNIFSFIIWIE
PKMRRENSSAIYLAALSLNDFLVLVFVMIQDLQYSWNKNVLRYSFCSIYM
VLSTCSQLFSPVLVLAFTIERWVAICYPFKRQSLCTPKRAIIVSFTLYLF
VLCYNIYNGFMWIYNERFDSCVFNQLETNGTDFQKQYIFATEIVFSGCVP
LLILGFNILVIKEMYRITKCNRTKSMGNCPQFHDPNQRFNNERSFLFTTI
MLLAVSFYLFFTTLPGGIMFALQQVITMPDENMNLSKIPSDPKWQFYFRV
SIIKAVIDELCISHYALNFVIYLITGKAFRKQFIDKIRKIITKFKLTDNF
FSNELVSLNKTNRMELTRENSLDFCHLNDANNSRRNRLTAKVI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR000276GPCR_Rhodpsn
IPR017452GPCR_Rhodpsn_7TM
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000276G protein-coupled receptor, rhodopsin-likePFAMPF000017tm_1coord: 40..275
e-value: 4.4E-17
score: 62.3
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 22..348
e-value: 4.1E-40
score: 139.7
NoneNo IPR availablePANTHERPTHR24243G-PROTEIN COUPLED RECEPTORcoord: 28..362
NoneNo IPR availableCDDcd149787tmA_FMRFamide_R-likecoord: 24..333
e-value: 1.70996E-29
score: 113.882
NoneNo IPR availableSUPERFAMILYSSF81321Family A G protein-coupled receptor-likecoord: 10..344
NoneNo IPR availableTMHMMTMhelixcoord: 61..83
NoneNo IPR availableTMHMMTMhelixcoord: 246..268
NoneNo IPR availableTMHMMTMhelixcoord: 27..49
NoneNo IPR availableTMHMMTMhelixcoord: 188..210
NoneNo IPR availableTMHMMTMhelixcoord: 98..120
NoneNo IPR availableTMHMMTMhelixcoord: 141..163
IPR017452GPCR, rhodopsin-like, 7TMPROSITEPS50262G_PROTEIN_RECEP_F1_2coord: 40..322
score: 20.592