SD1

Overview
NameSD1 (AHJ60961.1)
Smed IDSMED30026965
Length (bp)1512
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SD1 (SMED30026965) t-SNE clustered cells

Violin plots show distribution of expression levels for SD1 (SMED30026965) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SD1 (SMED30026965) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SD1 (SMED30026965) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30026965

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30026965h1SMcG0011292 Contig6955uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30026965h1SMcG0011292 Contig6955newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
X1 cellSMED30026965h1SMcG0011292 SmedASXL_010281SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30026965h1SMcG0011292 SmedASXL_010281SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
whole organismSMED30026965h1SMcG0011292 sd1smed_ncbi_20240424PMID:24523458
Lin et al., 2014
whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
BLAST of SD1 vs. Ensembl Human
Match: TEAD1 (TEA domain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11714])

HSP 1 Score: 239.965 bits (611), Expect = 2.104e-73
Identity = 166/469 (35.39%), Postives = 234/469 (49.89%), Query Frame = 1
Query:   97 MNSTAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE---------------SNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            M  ++W   SESP +N        +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ ++                +++ +S   Q +  T  +    L     P + PG       M  I     G      P  +    I       I   E     +PS     G              I   K+ L E   F  +    +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   +++D    Y ++ ++++S    +  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G     Q+ +Y +V +
Sbjct:    1 MEPSSWSG-SESPAEN--------MERMSDSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMS-SAQIVSATAIHNKLGLPGIPRP-TFPGAPGFWPGM--IQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGR------------SIGTTKLRLVEFSAFLEQ--QRDPDSYNK----HLFVHIGHANHS------YSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHG----AQHHIYRLVKD 426          
BLAST of SD1 vs. Ensembl Human
Match: TEAD1 (TEA domain transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11714])

HSP 1 Score: 238.424 bits (607), Expect = 1.003e-72
Identity = 165/466 (35.41%), Postives = 233/466 (50.00%), Query Frame = 1
Query:  106 TAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE---------------SNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            ++W   SESP +N        +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ ++                +++ +S   Q +  T  +    L     P + PG       M  I     G      P  +    I       I   E     +PS     G              I   K+ L E   F  +    +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   +++D    Y ++ ++++S    +  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G     Q+ +Y +V +
Sbjct:    4 SSWSG-SESPAEN--------MERMSDSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMS-SAQIVSATAIHNKLGLPGIPRP-TFPGAPGFWPGM--IQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGR------------SIGTTKLRLVEFSAFLEQ--QRDPDSYNK----HLFVHIGHANHS------YSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHG----AQHHIYRLVKD 426          
BLAST of SD1 vs. Ensembl Human
Match: TEAD3 (TEA domain transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11716])

HSP 1 Score: 233.802 bits (595), Expect = 7.113e-71
Identity = 156/445 (35.06%), Postives = 233/445 (52.36%), Query Frame = 1
Query:  217 EEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE-------SNVSTISEDG--QTIP--ETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLR-WGG-------------VRGFTDPV--TRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTF----LEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            + +GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSH+QVLARR+ +E        N+  +S+D   Q++    + Q ++  ++ N+  FS P    L Q + +   R W               ++ F  P    + PL  T  S   +  + +   + P    ++               I+ +++ L E   F       +P  +++    H F+H+G             P F    LE ++  QI+DKFP  + GLKEL        FFL+K W D+ S ++E     Y +S ++ ++    I ++TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   +++E LL + ++F V+  + G     Q+ +Y +V +
Sbjct:   30 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHLQVLARRKSREIQSKLKAMNLDQVSKDKALQSMASMSSAQIVSASVLQNK--FSPPS--PLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKPFAQPAYPIQPPLPPTLSSYEPLAPLPSAAASVPVWQDRT---------------IASSRLRLLEYSAFMEV--QRDPDTYSK----HLFVHIG----------QTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHG----AQHHVYKLVKD 435          
BLAST of SD1 vs. Ensembl Human
Match: TEAD3 (TEA domain transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:11716])

HSP 1 Score: 232.646 bits (592), Expect = 2.164e-70
Identity = 156/445 (35.06%), Postives = 233/445 (52.36%), Query Frame = 1
Query:  217 EEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE-------SNVSTISEDG--QTIP--ETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLR-WGG-------------VRGFTDPV--TRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTF----LEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            + +GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLAR++ +E        N+  +S+D   Q++    + Q ++  ++ N+  FS P    L Q + +   R W               ++ F  P    + PL  T  S   +  + +   + P    ++               I+ +++ L E   F       +P  +++    H F+H+G             P F    LE ++  QI+DKFP  + GLKEL        FFL+K W D+ S ++E     Y +S ++ ++    I ++TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   +++E LL + ++F V+  + G     Q+ +Y +V +
Sbjct:   30 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKDKALQSMASMSSAQIVSASVLQNK--FSPPS--PLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKPFAQPAYPIQPPLPPTLSSYEPLAPLPSAAASVPVWQDRT---------------IASSRLRLLEYSAFM--EVQRDPDTYSK----HLFVHIG----------QTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHG----AQHHVYKLVKD 435          
BLAST of SD1 vs. Ensembl Human
Match: TEAD2 (TEA domain transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11715])

HSP 1 Score: 224.557 bits (571), Expect = 4.152e-67
Identity = 154/438 (35.16%), Postives = 223/438 (50.91%), Query Frame = 1
Query:  223 DGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE-------SNVSTISEDG--QTIP--ETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGF------TDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDM-YSELREDDK----------YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            +GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E        NV  +S+D   QT+    + Q I+   +  +   + P    L Q        W G  G         P ++ P +++    +T  ++  +    P            S        +   ++ L E   F      +EP       + H F+H+      S    + G   LE ++  QI+DKFP  + GL+EL        FFL+K W D+ +    E+            Y +S ++++     +  ++K+C+F K +VE  +       +    + +   PMC+YL   L +L+Q  ++  MNSVLENF++ Q V   +T+E+LLC  Y+F V+  + G     Q+ +Y +V +
Sbjct:   42 EGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKALNVDQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQASELFQF-------WSGGSGPPWNVPDVKPFSQTPFTLSLTPPST--DLPGY---EPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAF------VEPPDAVDSYQRHLFVHI------SQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQELLLCTAYVFEVSTSERG----AQHHIYRLVRD 451          
BLAST of SD1 vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849])

HSP 1 Score: 140.584 bits (353), Expect = 1.230e-36
Identity = 62/76 (81.58%), Postives = 71/76 (93.42%), Query Frame = 1
Query:  214 AEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE 441
             + +GVWS DI+Q+FQEALAIYPPCGRRKII+SDEGKMYGRNELIARYIKLR GKTRTRKQVSSHIQVLAR++ ++
Sbjct:   14 GDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSHIQVLARKKLRD 89          

HSP 2 Score: 80.4925 bits (197), Expect = 5.020e-16
Identity = 49/154 (31.82%), Postives = 86/154 (55.84%), Query Frame = 1
Query:  937 INASQIWDKFPLQSGLKELI-GTYKNPCFFLLKIWIDM-YSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAE 1392
            I+ S  ++K+P    L+EL   + K   FFL K W ++  S+  ++ +Y +   + +    ++ ++T  C+F    VE  +       +    F++ N PMCDY+ K +  LK+    ETMN+VLENF+V Q V  +ET+E+L+ L ++F V++
Sbjct:  240 IDISVFYEKYP--KLLRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQ 391          
BLAST of SD1 vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849])

HSP 1 Score: 140.584 bits (353), Expect = 1.283e-36
Identity = 62/76 (81.58%), Postives = 71/76 (93.42%), Query Frame = 1
Query:  214 AEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE 441
             + +GVWS DI+Q+FQEALAIYPPCGRRKII+SDEGKMYGRNELIARYIKLR GKTRTRKQVSSHIQVLAR++ ++
Sbjct:   14 GDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSHIQVLARKKLRD 89          

HSP 2 Score: 80.4925 bits (197), Expect = 4.734e-16
Identity = 49/154 (31.82%), Postives = 86/154 (55.84%), Query Frame = 1
Query:  937 INASQIWDKFPLQSGLKELI-GTYKNPCFFLLKIWIDM-YSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAE 1392
            I+ S  ++K+P    L+EL   + K   FFL K W ++  S+  ++ +Y +   + +    ++ ++T  C+F    VE  +       +    F++ N PMCDY+ K +  LK+    ETMN+VLENF+V Q V  +ET+E+L+ L ++F V++
Sbjct:  247 IDISVFYEKYP--KLLRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQ 398          
BLAST of SD1 vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849])

HSP 1 Score: 140.584 bits (353), Expect = 1.551e-36
Identity = 62/76 (81.58%), Postives = 71/76 (93.42%), Query Frame = 1
Query:  214 AEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE 441
             + +GVWS DI+Q+FQEALAIYPPCGRRKII+SDEGKMYGRNELIARYIKLR GKTRTRKQVSSHIQVLAR++ ++
Sbjct:   31 GDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSHIQVLARKKLRD 106          

HSP 2 Score: 80.4925 bits (197), Expect = 4.736e-16
Identity = 49/154 (31.82%), Postives = 86/154 (55.84%), Query Frame = 1
Query:  937 INASQIWDKFPLQSGLKELI-GTYKNPCFFLLKIWIDM-YSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAE 1392
            I+ S  ++K+P    L+EL   + K   FFL K W ++  S+  ++ +Y +   + +    ++ ++T  C+F    VE  +       +    F++ N PMCDY+ K +  LK+    ETMN+VLENF+V Q V  +ET+E+L+ L ++F V++
Sbjct:  257 IDISVFYEKYP--KLLRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQ 408          
BLAST of SD1 vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849])

HSP 1 Score: 140.584 bits (353), Expect = 1.608e-36
Identity = 62/76 (81.58%), Postives = 71/76 (93.42%), Query Frame = 1
Query:  214 AEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE 441
             + +GVWS DI+Q+FQEALAIYPPCGRRKII+SDEGKMYGRNELIARYIKLR GKTRTRKQVSSHIQVLAR++ ++
Sbjct:   31 GDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSHIQVLARKKLRD 106          

HSP 2 Score: 80.8777 bits (198), Expect = 4.100e-16
Identity = 49/154 (31.82%), Postives = 86/154 (55.84%), Query Frame = 1
Query:  937 INASQIWDKFPLQSGLKELI-GTYKNPCFFLLKIWIDM-YSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAE 1392
            I+ S  ++K+P    L+EL   + K   FFL K W ++  S+  ++ +Y +   + +    ++ ++T  C+F    VE  +       +    F++ N PMCDY+ K +  LK+    ETMN+VLENF+V Q V  +ET+E+L+ L ++F V++
Sbjct:  264 IDISVFYEKYP--KLLRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQ 415          
BLAST of SD1 vs. Ensembl Celegans
Match: egl-44 (Transcription enhancer factor-like protein egl-44 [Source:UniProtKB/Swiss-Prot;Acc:Q19849])

HSP 1 Score: 140.584 bits (353), Expect = 3.861e-36
Identity = 62/76 (81.58%), Postives = 71/76 (93.42%), Query Frame = 1
Query:  214 AEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE 441
             + +GVWS DI+Q+FQEALAIYPPCGRRKII+SDEGKMYGRNELIARYIKLR GKTRTRKQVSSHIQVLAR++ ++
Sbjct:   88 GDAEGVWSIDIDQAFQEALAIYPPCGRRKIIISDEGKMYGRNELIARYIKLRCGKTRTRKQVSSHIQVLARKKLRD 163          

HSP 2 Score: 80.8777 bits (198), Expect = 4.787e-16
Identity = 49/154 (31.82%), Postives = 86/154 (55.84%), Query Frame = 1
Query:  937 INASQIWDKFPLQSGLKELI-GTYKNPCFFLLKIWIDM-YSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAE 1392
            I+ S  ++K+P    L+EL   + K   FFL K W ++  S+  ++ +Y +   + +    ++ ++T  C+F    VE  +       +    F++ N PMCDY+ K +  LK+    ETMN+VLENF+V Q V  +ET+E+L+ L ++F V++
Sbjct:  314 IDISVFYEKYP--KLLRELFEKSEKKDVFFLAKCWANINVSDDVQNCQYAVDSFYSSREKFQLKVSTMACSFGNQAVEKIEQYFPIEFDGSYSFILNNSPMCDYMVKFIAELKKLNVIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQ 465          
BLAST of SD1 vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0340115)

HSP 1 Score: 184.882 bits (468), Expect = 2.573e-53
Identity = 142/431 (32.95%), Postives = 215/431 (49.88%), Query Frame = 1
Query:  154 NSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSG-LKELIGTYKNPCFFLLKIWIDMYSEL----REDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            + N D+ +  D  D+ D   A+ +GVWS DIEQSFQEAL+IYPPCGRRKIILSDEGKMYGRNELIARYI     K RT K  +        R+   S++  ++   + + E    I  +       F  PG +  + + D  D     ++ F  P    P    K S                 G ++G  +  S +      I+ +K  L E   F ++    E  H       H F+ LG   + S  L       LE ++  QI+DKFP +SG LK+L        F+L+K W D+ ++L       D Y ++ +++++    +  +T +C+F K +VE  +       N+   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:    4 SKNLDVGDMSD--DEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYI-----KLRTGKTRT--------RKQVSSHIQVLAR--RKLREIQAKIKVQ-------FWQPG-LQPSTSQDFYDY---SIKPFPQP----PYPAGKTSTAV-------------SGDETG--IPPSQLPWEGRAIATHKFRLLEFTAF-MEIQRDEIYHR------HLFVQLGGKPSFSDPL-------LETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 372          
BLAST of SD1 vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0074100)

HSP 1 Score: 151.754 bits (382), Expect = 5.722e-41
Identity = 81/132 (61.36%), Postives = 93/132 (70.45%), Query Frame = 1
Query:  154 NSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQ--TIPETTQNINFKLMDNEYPFSNP 543
            + N D+ +  D  D+ D   A+ +GVWS DIEQSFQEAL+IYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E       +  Q    P T+Q+I         PF  P
Sbjct:    4 SKNLDVGDMSD--DEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIKVQFWQPGLQPSTSQDIK--------PFPQP 125          

HSP 2 Score: 110.538 bits (275), Expect = 2.625e-26
Identity = 65/196 (33.16%), Postives = 109/196 (55.61%), Query Frame = 1
Query:  859 HEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSG-LKELIGTYKNPCFFLLKIWIDMYSEL----REDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            H F+ LG   + S  L       LE ++  QI+DKFP +SG LK+L        F+L+K W D+ ++L       D Y ++ +++++    +  +T +C+F K +VE  +       N+   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:  180 HLFVQLGGKPSFSDPL-------LETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 367          
BLAST of SD1 vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0308132)

HSP 1 Score: 151.754 bits (382), Expect = 5.722e-41
Identity = 81/132 (61.36%), Postives = 93/132 (70.45%), Query Frame = 1
Query:  154 NSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQ--TIPETTQNINFKLMDNEYPFSNP 543
            + N D+ +  D  D+ D   A+ +GVWS DIEQSFQEAL+IYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E       +  Q    P T+Q+I         PF  P
Sbjct:    4 SKNLDVGDMSD--DEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIKVQFWQPGLQPSTSQDIK--------PFPQP 125          

HSP 2 Score: 110.538 bits (275), Expect = 2.625e-26
Identity = 65/196 (33.16%), Postives = 109/196 (55.61%), Query Frame = 1
Query:  859 HEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSG-LKELIGTYKNPCFFLLKIWIDMYSEL----REDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            H F+ LG   + S  L       LE ++  QI+DKFP +SG LK+L        F+L+K W D+ ++L       D Y ++ +++++    +  +T +C+F K +VE  +       N+   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:  180 HLFVQLGGKPSFSDPL-------LETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 367          
BLAST of SD1 vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0074101)

HSP 1 Score: 151.754 bits (382), Expect = 5.722e-41
Identity = 81/132 (61.36%), Postives = 93/132 (70.45%), Query Frame = 1
Query:  154 NSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQ--TIPETTQNINFKLMDNEYPFSNP 543
            + N D+ +  D  D+ D   A+ +GVWS DIEQSFQEAL+IYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E       +  Q    P T+Q+I         PF  P
Sbjct:    4 SKNLDVGDMSD--DEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIKVQFWQPGLQPSTSQDIK--------PFPQP 125          

HSP 2 Score: 110.538 bits (275), Expect = 2.625e-26
Identity = 65/196 (33.16%), Postives = 109/196 (55.61%), Query Frame = 1
Query:  859 HEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSG-LKELIGTYKNPCFFLLKIWIDMYSEL----REDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            H F+ LG   + S  L       LE ++  QI+DKFP +SG LK+L        F+L+K W D+ ++L       D Y ++ +++++    +  +T +C+F K +VE  +       N+   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:  180 HLFVQLGGKPSFSDPL-------LETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 367          
BLAST of SD1 vs. Ensembl Fly
Match: sd (gene:FBgn0003345 transcript:FBtr0308130)

HSP 1 Score: 151.754 bits (382), Expect = 5.722e-41
Identity = 81/132 (61.36%), Postives = 93/132 (70.45%), Query Frame = 1
Query:  154 NSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQ--TIPETTQNINFKLMDNEYPFSNP 543
            + N D+ +  D  D+ D   A+ +GVWS DIEQSFQEAL+IYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E       +  Q    P T+Q+I         PF  P
Sbjct:    4 SKNLDVGDMSD--DEKDLSSADAEGVWSPDIEQSFQEALSIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKIKVQFWQPGLQPSTSQDIK--------PFPQP 125          

HSP 2 Score: 110.538 bits (275), Expect = 2.625e-26
Identity = 65/196 (33.16%), Postives = 109/196 (55.61%), Query Frame = 1
Query:  859 HEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSG-LKELIGTYKNPCFFLLKIWIDMYSEL----REDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            H F+ LG   + S  L       LE ++  QI+DKFP +SG LK+L        F+L+K W D+ ++L       D Y ++ +++++    +  +T +C+F K +VE  +       N+   + ++  PMC+Y+   + +LK   ++  MNSVLENF++ Q ++  ET+E LLC+ Y+F VA ++SG   H  YRL
Sbjct:  180 HLFVQLGGKPSFSDPL-------LETVDIRQIFDKFPEKSGGLKDLYEKGPQNAFYLVKCWADLNTDLTTGSETGDFYGVTSQYESNENVVLVCSTIVCSFGKQVVEKVESEYSRLENNRYVYRIQRSPMCEYMINFIQKLKNLPERYMMNSVLENFTILQVMRARETQETLLCIAYVFEVAAQNSGTTHHI-YRL 367          
BLAST of SD1 vs. Ensembl Zebrafish
Match: tead1a (TEA domain family member 1a [Source:ZFIN;Acc:ZDB-GENE-040426-2101])

HSP 1 Score: 244.202 bits (622), Expect = 3.128e-75
Identity = 157/438 (35.84%), Postives = 229/438 (52.28%), Query Frame = 1
Query:  154 NSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKA---PNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            ++  DIE   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E +        +    T +N     M            A++  +    L    + G T     +        +   ++ +N+ I +    T        + + + + P     IG  ++ + +  A      +P  +N+    H F+H+G  + S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   ++ED    Y ++ ++++S    I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   ET+E LLC+  +F V+  + G     Q+ +Y +V +
Sbjct:   11 SAGEDIERMSDSADKPMDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREFH-------SKLKDHTVKNDAINRMGGISSAQIVSATAIHSRLGLAGLPRSALPGATGIWQVSTGQPGSSQDVKPFSQQNYPIQTT---TAIAAYESSTALSAAVPPWHGRSIGTSKLRLVEFSAFLEHQRDPDLYNK----HLFVHIGQTNYS------YSDALLETVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQEDSGSFYGVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYKISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVSNRETQETLLCMACVFEVSNSEHG----AQHHIYRLVKD 422          
BLAST of SD1 vs. Ensembl Zebrafish
Match: tead1b (TEA domain family member 1b [Source:ZFIN;Acc:ZDB-GENE-091013-5])

HSP 1 Score: 230.335 bits (586), Expect = 2.685e-70
Identity = 155/419 (36.99%), Postives = 223/419 (53.22%), Query Frame = 1
Query:  184 DNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E + S + +         Q++  K +      S+   V+     + + L       F       P  I    +  +W V      +P  G   G+   +  +   L  +S + +    ++VFQ          +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   ++++    Y ++ ++++     I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G   H  YRL
Sbjct:    3 DSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRELH-SKLKD---------QSVKDKALQTMASMSSAQIVSATAIHNKLGLPGIPRPAFPGAAGVRPF-IQFTYSACLWTVGE--TGAPG-GNPRGHRGNKHVLAVILIRLSVSNMFF--VVVFQ----------YNK----HLFVHIGQTNHS------YNDALLESVDIRQIYDKFPEKKGGLKELFGKGPQNSFFLIKFWADLNCNIQDETGAFYGVTSQYESPENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI-YRL 382          
BLAST of SD1 vs. Ensembl Zebrafish
Match: tead1b (TEA domain family member 1b [Source:ZFIN;Acc:ZDB-GENE-091013-5])

HSP 1 Score: 229.95 bits (585), Expect = 3.816e-70
Identity = 152/419 (36.28%), Postives = 219/419 (52.27%), Query Frame = 1
Query:  184 DNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E + S + +         Q++  K +      S+   V+     + +     G+ G   P       +   S   ++     +      G +       +        I  +K+ L E   F       +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   ++++    Y ++ ++++     I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G   H  YRL
Sbjct:    3 DSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRELH-SKLKD---------QSVKDKALQTMASMSSAQIVSATAIHNKL-----GLPGIPRPAFPGAAGVRPASGTQLYTYRVQLW----LGYEPPTAPAPTVPAWQGRSIGTSKLRLVEFSAFL--EHQRDPDSYNK----HLFVHIGQTNHS------YNDALLESVDIRQIYDKFPEKKGGLKELFGKGPQNSFFLIKFWADLNCNIQDETGAFYGVTSQYESPENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI-YRL 387          
BLAST of SD1 vs. Ensembl Zebrafish
Match: tead1b (TEA domain family member 1b [Source:ZFIN;Acc:ZDB-GENE-091013-5])

HSP 1 Score: 205.297 bits (521), Expect = 1.693e-60
Identity = 149/437 (34.10%), Postives = 215/437 (49.20%), Query Frame = 1
Query:  184 DNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQ---------------VSSHIQVLARRRHKESNVSTISE--DGQTIPETTQNINFKLMDNEYP-FSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQ               + + I+V   +  K+  + T++     Q +  T  +    L     P F     V L+  +  + L +        P  +    I      TI + E     +P+     G              I  +K+ L E   F       +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   ++++    Y ++ ++++     I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G   H  YRL
Sbjct:    3 DSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVRLDQSVKDKALQTMASMSSAQIVSATAIHNKLGLPGIPRPAFPGAYVVLLSPVLILLCLCFS-----IKPFAQQAYPIQPAVTTTISSYEPPTAPAPTVPAWQGR------------SIGTSKLRLVEFSAFL--EHQRDPDSYNK----HLFVHIGQTNHS------YNDALLESVDIRQIYDKFPEKKGGLKELFGKGPQNSFFLIKFWADLNCNIQDETGAFYGVTSQYESPENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI-YRL 407          
BLAST of SD1 vs. Ensembl Zebrafish
Match: tead1b (TEA domain family member 1b [Source:ZFIN;Acc:ZDB-GENE-091013-5])

HSP 1 Score: 199.904 bits (507), Expect = 6.347e-59
Identity = 140/419 (33.41%), Postives = 209/419 (49.88%), Query Frame = 1
Query:  184 DNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRT             R+   S++  ++   + + E    I               R+AL     A       ++ F         ++T  + +++W   +   N   H    GN    + ++     I  +   +  ++VFQ          +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   ++++    Y ++ ++++     I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G   H  YRL
Sbjct:    3 DSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRT-------------RKQVSSHIQVLAR--KKVREIQAAIKV-------------RLALPSCRGAFHRHGYSIKPFAQQAYPIQPAVT-TTISSMWGFHSPGGNPRGH---RGNKHVLAVIL-----IRLSVSNMFFVVVFQ----------YNK----HLFVHIGQTNHS------YNDALLESVDIRQIYDKFPEKKGGLKELFGKGPQNSFFLIKFWADLNCNIQDETGAFYGVTSQYESPENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI-YRL 361          
BLAST of SD1 vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106])

HSP 1 Score: 240.736 bits (613), Expect = 6.462e-74
Identity = 158/437 (36.16%), Postives = 229/437 (52.40%), Query Frame = 1
Query:  175 EFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDP---------------VTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            + GD+ + + ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E  + +  +D     +  Q++    M +    S     A+   +    +    V+ F+ P                  +P S++   +   W  +   I +P                         K+ L E + F  +    EP  +N+    H ++H+   SN S          LE ++  QI+DKFP  + GLKEL        FFL+K W D+ + ++++    Y +S ++++     I  ++K+C+F K +VE  +       N    + +   PMC+YL   + +LKQ  +K  MNSVLENF++ Q V   +T+E+LLC+ Y+F V+  + G   H  YRL
Sbjct:   16 DLGDSMEKSLDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRE--IQSKLKDQVAKDKALQSM--AAMSSAQLISA---TAIQNKLGVSSISQAPVKPFSQPPYPLQSAAPPPAVPGYNASPASLSPVPSGPAW--QGRSIGTP-------------------------KLRLVEFLAFMEQ--QGEPDAYNK----HLYVHIS-QSNPSY-----SDALLESVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNTSIQDEPGVFYGVSSQYESPENMTITCSSKVCSFGKQVVEKVETEYARFENGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHI-YRL 403          
BLAST of SD1 vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106])

HSP 1 Score: 238.039 bits (606), Expect = 3.333e-73
Identity = 156/422 (36.97%), Postives = 223/422 (52.84%), Query Frame = 1
Query:  175 EFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            + GD+ + + ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E          Q+  + ++   + +   + PFS P             L+             +P S++   +   W  +   I +P                         K+ L E + F  +    EP  +N+    H ++H+   SN S          LE ++  QI+DKFP  + GLKEL        FFL+K W D+ + ++++    Y +S ++++     I  ++K+C+F K +VE  +       N    + +   PMC+YL   + +LKQ  +K  MNSVLENF++ Q V   +T+E+LLC+ Y+F V+  + G   H  YRL
Sbjct:   18 DLGDSMEKSLDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREI---------QSKLKVSKAYVYHICHVK-PFSQP----------PYPLQSAAPPPAVPGYNASPASLSPVPSGPAW--QGRSIGTP-------------------------KLRLVEFLAFMEQ--QGEPDAYNK----HLYVHIS-QSNPSY-----SDALLESVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNTSIQDEPGVFYGVSSQYESPENMTITCSSKVCSFGKQVVEKVETEYARFENGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHI-YRL 377          
BLAST of SD1 vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106])

HSP 1 Score: 239.58 bits (610), Expect = 3.531e-73
Identity = 162/441 (36.73%), Postives = 231/441 (52.38%), Query Frame = 1
Query:  175 EFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE-------SNVSTISED----GQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDL--RWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGP------ISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            + GD+ + + ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E        N+  +++D          + Q I+   + N+   S+  +          D    W G           P    K  +   + +++    +P       N    S      GP      I   K+ L E + F  +    EP  +N+    H ++H+   SN S          LE ++  QI+DKFP  + GLKEL        FFL+K W D+ + ++++    Y +S ++++     I  ++K+C+F K +VE  +       N    + +   PMC+YL   + +LKQ  +K  MNSVLENF++ Q V   +T+E+LLC+ Y+F V+  + G   H  YRL
Sbjct:   18 DLGDSMEKSLDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKAMNMDQVAKDKALQSMAAMSSAQLISATAIQNKLGVSSISQAPFPPTPGTPDFFQFWPGGG------QPRPTQDVKPFSQPPYPLQS---AAPPPAVPGYNASPASLSPVPSGPAWQGRSIGTPKLRLVEFLAFMEQ--QGEPDAYNK----HLYVHIS-QSNPSY-----SDALLESVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNTSIQDEPGVFYGVSSQYESPENMTITCSSKVCSFGKQVVEKVETEYARFENGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHI-YRL 434          
BLAST of SD1 vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106])

HSP 1 Score: 234.958 bits (598), Expect = 3.760e-72
Identity = 158/414 (38.16%), Postives = 219/414 (52.90%), Query Frame = 1
Query:  217 EEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGP------ISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            + +GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E                   I  KL D         +VA ++ + ++       +  +    +N L ++  S              P+ G  S N    S      GP      I   K+ L E + F  +    EP  +N+    H ++H+   SN S          LE ++  QI+DKFP  + GLKEL        FFL+K W D+ + ++++    Y +S ++++     I  ++K+C+F K +VE  +       N    + +   PMC+YL   + +LKQ  +K  MNSVLENF++ Q V   +T+E+LLC+ Y+F V+  + G   H  YRL
Sbjct:    8 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRE-------------------IQSKLKD---------QVAKDKALQSMAA-MSSAQLISATAIQNKLGVSSISQAPF---------PPTPGV-SYNASPASLSPVPSGPAWQGRSIGTPKLRLVEFLAFMEQ--QGEPDAYNK----HLYVHISQ-SNPSY-----SDALLESVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNTSIQDEPGVFYGVSSQYESPENMTITCSSKVCSFGKQVVEKVETEYARFENGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHI-YRL 369          
BLAST of SD1 vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:Xenbase;Acc:XB-GENE-998106])

HSP 1 Score: 235.343 bits (599), Expect = 1.357e-71
Identity = 162/437 (37.07%), Postives = 230/437 (52.63%), Query Frame = 1
Query:  175 EFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR--RHKESNVS-TISED----GQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLR--WGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGP------ISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            + GD+ + + ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR  R  +S +   +++D          + Q I+   + N+   S+  +          D    W G           P    K  +   + +++    +P       N    S      GP      I   K+ L E + F  +    EP  +N+    H ++H+   SN S          LE ++  QI+DKFP  + GLKEL        FFL+K W D+ + ++++    Y +S ++++     I  ++K+C+F K +VE  +       N    + +   PMC+YL   + +LKQ  +K  MNSVLENF++ Q V   +T+E+LLC+ Y+F V+  + G   H  YRL
Sbjct:   18 DLGDSMEKSLDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVAKDKALQSMAAMSSAQLISATAIQNKLGVSSISQAPFPPTPGTPDFFQFWPGGG------QPRPTQDVKPFSQPPYPLQS---AAPPPAVPGYNASPASLSPVPSGPAWQGRSIGTPKLRLVEFLAFMEQ--QGEPDAYNK----HLYVHIS-QSNPSY-----SDALLESVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNTSIQDEPGVFYGVSSQYESPENMTITCSSKVCSFGKQVVEKVETEYARFENGRFLYRIHRSPMCEYLINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQELLLCIAYVFEVSTSEHGAQHHI-YRL 430          
BLAST of SD1 vs. Ensembl Mouse
Match: Tead1 (TEA domain family member 1 [Source:MGI Symbol;Acc:MGI:101876])

HSP 1 Score: 236.884 bits (603), Expect = 1.806e-72
Identity = 159/454 (35.02%), Postives = 229/454 (50.44%), Query Frame = 1
Query:  169 IEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRR----HKESNVSTISEDGQ-------TIPETTQNINFKLMDNEY-------------PFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+    H +  V+++ +  +           + Q ++   + N+              P   PG +   Q   + D++         P  +    I       I   E     +PS     G              I   K+ L E   F  +    +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   +++D    Y +S ++++S    +  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G     Q+ +Y +V +
Sbjct:    1 MERMSDSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKVTSMDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVK---------PFVQQAYPIQPAVTAPIPGFEPTSAPAPSVPAWQGR------------SIGTTKLRLVEFSAFLEQ--QRDPDSYNK----HLFVHIGHANHS------YSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHG----AQHHIYRLVKD 415          
BLAST of SD1 vs. Ensembl Mouse
Match: Tead1 (TEA domain family member 1 [Source:MGI Symbol;Acc:MGI:101876])

HSP 1 Score: 234.958 bits (598), Expect = 7.881e-72
Identity = 157/450 (34.89%), Postives = 226/450 (50.22%), Query Frame = 1
Query:  169 IEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQ-------TIPETTQNINFKLMDNEY-------------PFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ ++ +     +  +           + Q ++   + N+              P   PG +   Q   + D++         P  +    I       I   E     +PS     G              I   K+ L E   F  +    +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   +++D    Y +S ++++S    +  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G     Q+ +Y +V +
Sbjct:    1 MERMSDSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVK---------PFVQQAYPIQPAVTAPIPGFEPTSAPAPSVPAWQGR------------SIGTTKLRLVEFSAFLEQ--QRDPDSYNK----HLFVHIGHANHS------YSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHG----AQHHIYRLVKD 411          
BLAST of SD1 vs. Ensembl Mouse
Match: Tead1 (TEA domain family member 1 [Source:MGI Symbol;Acc:MGI:101876])

HSP 1 Score: 234.958 bits (598), Expect = 7.881e-72
Identity = 157/450 (34.89%), Postives = 226/450 (50.22%), Query Frame = 1
Query:  169 IEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQ-------TIPETTQNINFKLMDNEY-------------PFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ ++ +     +  +           + Q ++   + N+              P   PG +   Q   + D++         P  +    I       I   E     +PS     G              I   K+ L E   F  +    +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   +++D    Y +S ++++S    +  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G     Q+ +Y +V +
Sbjct:    1 MERMSDSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVK---------PFVQQAYPIQPAVTAPIPGFEPTSAPAPSVPAWQGR------------SIGTTKLRLVEFSAFLEQ--QRDPDSYNK----HLFVHIGHANHS------YSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHG----AQHHIYRLVKD 411          
BLAST of SD1 vs. Ensembl Mouse
Match: Tead1 (TEA domain family member 1 [Source:MGI Symbol;Acc:MGI:101876])

HSP 1 Score: 234.572 bits (597), Expect = 1.196e-71
Identity = 159/454 (35.02%), Postives = 229/454 (50.44%), Query Frame = 1
Query:  169 IEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVST-ISEDGQTIPE----------TTQNINFKLMDNEY-------------PFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLAR++ +E   +  ++   QT  +          + Q ++   + N+              P   PG +   Q   + D++         P  +    I       I   E     +PS     G              I   K+ L E   F  +    +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   +++D    Y +S ++++S    +  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G     Q+ +Y +V +
Sbjct:    1 MERMSDSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVTSMDQTAKDKALQHMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVK---------PFVQQAYPIQPAVTAPIPGFEPTSAPAPSVPAWQGR------------SIGTTKLRLVEFSAFLEQ--QRDPDSYNK----HLFVHIGHANHS------YSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHG----AQHHIYRLVKD 415          
BLAST of SD1 vs. Ensembl Mouse
Match: Tead4 (TEA domain family member 4 [Source:MGI Symbol;Acc:MGI:106907])

HSP 1 Score: 223.402 bits (568), Expect = 1.086e-67
Identity = 146/408 (35.78%), Postives = 208/408 (50.98%), Query Frame = 1
Query:  223 DGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTI--PETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            +GVWS +IE+SFQEALAIYPPCGRRKIIL++EGKMYGRNELIAR+IKLRTGKTRTRKQVSSHIQVLARR+ +E         G     P T+ ++      N YP   P  +                 GF  P    P           W   +                           I+ +K+ + E   F  +    +P  +N+    H F+H   +S SS    +    +LE ++  QI+DKFP  + GLKEL     +  FFL+K W D+ + + ++    Y +S ++++     I  +TK+C+F K +VE  +       N    + +   P+C+Y+   + +LK   +K  MNSVLENF++ Q V   +T+E LLC+ Y+F V+  + G   H  YRL
Sbjct:   33 EGVWSPEIERSFQEALAIYPPCGRRKIILTEEGKMYGRNELIARHIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKFWQGALPGQPGTSHDVK-PFSQNTYPVQPPLPLP----------------GFESPA--GPTPSPSAPLAPPWQGRS---------------------------IASSKLWMLEFSAFLER--QQDPDTYNK----HLFVH---ISQSSPSYSD---PYLETVDIRQIYDKFPEKKGGLKELFERGPSNAFFLVKFWADLNTNIDDEGSAFYGVSSQYESPENMIITCSTKVCSFGKQVVEKVETEYARYENGHYLYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASEHGAQHHI-YRL 381          
BLAST of SD1 vs. UniProt/SwissProt
Match: sp|P30051|TEAD1_MOUSE (Transcriptional enhancer factor TEF-1 OS=Mus musculus OX=10090 GN=Tead1 PE=1 SV=2)

HSP 1 Score: 240.736 bits (613), Expect = 5.878e-73
Identity = 167/475 (35.16%), Postives = 237/475 (49.89%), Query Frame = 1
Query:   97 MNSTAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE---------------SNVSTISEDGQTIPETTQNINFKLMDNEYP-FSN-----PGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            M  ++W   SESP +N        +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ ++                +++ +S   Q +  T  +    L     P F       PG +   Q   + D++         P  +    I       I   E     +PS     G              I   K+ L E   F  +    +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   +++D    Y +S ++++S    +  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G     Q+ +Y +V +
Sbjct:    1 MEPSSWSG-SESPAEN--------MERMSDSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMS-SAQIVSATAIHNKLGLPGIPRPTFPGGPGFWPGMIQTGQPGSSQDVK---------PFVQQAYPIQPAVTAPIPGFEPTSAPAPSVPAWQGR------------SIGTTKLRLVEFSAFLEQ--QRDPDSYNK----HLFVHIGHANHS------YSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVSSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHG----AQHHIYRLVKD 426          
BLAST of SD1 vs. UniProt/SwissProt
Match: sp|P28347|TEAD1_HUMAN (Transcriptional enhancer factor TEF-1 OS=Homo sapiens OX=9606 GN=TEAD1 PE=1 SV=2)

HSP 1 Score: 239.965 bits (611), Expect = 1.011e-72
Identity = 166/469 (35.39%), Postives = 234/469 (49.89%), Query Frame = 1
Query:   97 MNSTAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE---------------SNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            M  ++W   SESP +N        +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ ++                +++ +S   Q +  T  +    L     P + PG       M  I     G      P  +    I       I   E     +PS     G              I   K+ L E   F  +    +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   +++D    Y ++ ++++S    +  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G     Q+ +Y +V +
Sbjct:    1 MEPSSWSG-SESPAEN--------MERMSDSADKPIDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQHMAAMS-SAQIVSATAIHNKLGLPGIPRP-TFPGAPGFWPGM--IQTGQPGSSQDVKPFVQQAYPIQPAVTAPIPGFEPASAPAPSVPAWQGR------------SIGTTKLRLVEFSAFLEQ--QRDPDSYNK----HLFVHIGHANHS------YSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQDDAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHG----AQHHIYRLVKD 426          
BLAST of SD1 vs. UniProt/SwissProt
Match: sp|P48984|TEAD4_CHICK (Transcriptional enhancer factor TEF-3 OS=Gallus gallus OX=9031 GN=TEAD4 PE=2 SV=1)

HSP 1 Score: 235.728 bits (600), Expect = 7.787e-71
Identity = 164/460 (35.65%), Postives = 224/460 (48.70%), Query Frame = 1
Query:  130 SPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR--RHKESNVSTISEDGQTIP-ETTQNINFKLMDNEYPFSNP---GRVALNQNMDAIDL---RWGGVRGF--------------TDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            SP   +  N +   E      D+  E      GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR  R  ++ +     D      E  Q    K M +    S+       A +  M    L    +  V GF                P T+ P ++               +  P   + +G     S        ++ +K+ + E   F      LE          H F+H+G  SN S         +LE ++  QI+DKFP  + GLKEL        FFL+K W D+ + + ++ +  Y +S ++++     I  +TK+C+F K +VE  +       N    + +   P+C+Y+   + +LK   +K  MNSVLENF++ Q V   +T+E LLC+ Y+F V+  D G   H  YRL
Sbjct:    7 SPASPEGSNDSGGSEALDKPIDNDAE------GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQAKLKKTQVDKYDFSSEKDQTAKDKAMQSIATMSSAQIISATAFHSKMALPGLPRSAYPAVSGFWQGALPGQAGSSQDVKPFTQQPYALQPS------------LPLPGFDSPTGLPPSSSTPAWQGRRVASSKLWMLEFSAF------LEQQQDQDTYNKHLFVHIG-QSNPSY-----SDPYLEAVDIRQIYDKFPEKKGGLKELFERGPANAFFLVKFWADLNTNIEDESRSFYGVSSQYESPENMVITCSTKVCSFGKQVVEKVETEYAHYENGHYAYRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAYVFEVSASDHGAQHHI-YRL 435          
BLAST of SD1 vs. UniProt/SwissProt
Match: sp|Q90701|TEAD3_CHICK (Transcriptional enhancer factor TEF-5 OS=Gallus gallus OX=9031 GN=TEAD3 PE=2 SV=2)

HSP 1 Score: 233.802 bits (595), Expect = 3.072e-70
Identity = 159/442 (35.97%), Postives = 232/442 (52.49%), Query Frame = 1
Query:  172 EEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR-------RHKESNVSTISEDG--QTIP--ETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVS--NLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            E+  D  D + ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRT+KQVSSH+QVLARR       + K  N+  +S+D   Q++    + Q ++  ++ N+     P   A+     A    W G      P    P    K      + ++  M  S +       +   ++ V       I+  K+ L E   F ++ P     +       H F+H+G  + S           LE ++  QI+DKFP  + GLKEL        FFLLK W D+ S +++     Y +S ++ ++    I ++TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   +T+E LLC+ ++F V+  + G     Q+ +Y +V +
Sbjct:   17 EDGQDGMDKSLDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTKKQVSSHLQVLARREISGDSSKLKAMNLDQVSKDKAFQSMASMSSAQIVSASVLQNKLSPPPPLPQAV---FSAAPRFWSG----PIPGQPGPSQDIKPFAQPAYPIQPPMPPSLASYEPLAPLPPAASAVPVWQDRTIASAKLRLLEYSAF-MEVPRDAETYSK-----HLFVHIGQTNPS------YSDPLLEAMDIRQIYDKFPEKKGGLKELYERGPQNSFFLLKFWADLNSTIQDGPGTFYGVSSQYSSAENMTITVSTKVCSFGKQVVEKVETEYARLENSRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTQETLLCIAFVFEVSTSEHG----AQHHVYKLVKD 433          
BLAST of SD1 vs. UniProt/SwissProt
Match: sp|Q99594|TEAD3_HUMAN (Transcriptional enhancer factor TEF-5 OS=Homo sapiens OX=9606 GN=TEAD3 PE=1 SV=2)

HSP 1 Score: 232.646 bits (592), Expect = 8.864e-70
Identity = 156/445 (35.06%), Postives = 233/445 (52.36%), Query Frame = 1
Query:  217 EEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE-------SNVSTISEDG--QTIP--ETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLR-WGG-------------VRGFTDPV--TRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTF----LEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            + +GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLAR++ +E        N+  +S+D   Q++    + Q ++  ++ N+  FS P    L Q + +   R W               ++ F  P    + PL  T  S   +  + +   + P    ++               I+ +++ L E   F       +P  +++    H F+H+G             P F    LE ++  QI+DKFP  + GLKEL        FFL+K W D+ S ++E     Y +S ++ ++    I ++TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   +++E LL + ++F V+  + G     Q+ +Y +V +
Sbjct:   30 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKDKALQSMASMSSAQIVSASVLQNK--FSPPS--PLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKPFAQPAYPIQPPLPPTLSSYEPLAPLPSAAASVPVWQDRT---------------IASSRLRLLEYSAFM--EVQRDPDTYSK----HLFVHIG----------QTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHG----AQHHVYKLVKD 435          
BLAST of SD1 vs. TrEMBL
Match: W8E2X6 (SD1 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=sd1 PE=2 SV=1)

HSP 1 Score: 872.078 bits (2252), Expect = 0.000e+0
Identity = 418/418 (100.00%), Postives = 418/418 (100.00%), Query Frame = 1
Query:   97 MNSTAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETE 1350
            MNSTAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETE
Sbjct:    1 MNSTAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETE 418          
BLAST of SD1 vs. TrEMBL
Match: A0A4W4GMM8 (TEA domain-containing protein OS=Electrophorus electricus OX=8005 PE=4 SV=1)

HSP 1 Score: 254.218 bits (648), Expect = 5.123e-76
Identity = 169/429 (39.39%), Postives = 233/429 (54.31%), Query Frame = 1
Query:  172 EEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQ-TIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVT-RNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTF----LEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            EE  +  D   E+ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E  V    +  +    ++  N++   + +   F N  ++AL           GGV   T+P + +N +  T     T +   + +  SPS     G  +  S            K+ + E   F ++ P  +P ++N+    H F+H+G             PTF    LE ++  QI+DKFP  + GLKEL        FFL+K W D+   L++D    Y +S ++++S    I  +TK+C+F K +VE  +       N    F +   P+C+Y+   + +LK   +K  MNSVLENF++ Q V   +T E LLC+ Y+F V+  + G   H  YRL
Sbjct:    5 EELSETLDKPLENDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQVKLKDQAAKDKALQSMANMSSAQIISATAFQN--KMALQGLPRPPYPGSGGVSSVTEPFSQQNYVMQTTGPPITGYESTSGLTMSPSAPPWQGRSIASS------------KLRMLEFSAF-LEQPQ-DPENFNK----HLFVHIG----------QSNPTFSDPYLEAVDIRQIYDKFPEKKGGLKELFEKGPANAFFLVKFWADLSVNLQDDSSFFYGVSSQYESSDNMIITSSTKVCSFGKQVVEKVETEYARFENGRYVFRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTLETLLCVAYVFEVSTSEHGAQHHI-YRL 400          
BLAST of SD1 vs. TrEMBL
Match: A0A4W4GMN8 (TEA domain-containing protein OS=Electrophorus electricus OX=8005 PE=4 SV=1)

HSP 1 Score: 253.062 bits (645), Expect = 3.220e-75
Identity = 166/428 (38.79%), Postives = 232/428 (54.21%), Query Frame = 1
Query:  172 EEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQ-TIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTF----LEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            EE  +  D   E+ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E  V    +  +    ++  N++   + +   F N  ++AL           GGV   T+P ++         N  +      +     + + SG  +  S        I+ +K+ + E   F ++ P  +P ++N+    H F+H+G             PTF    LE ++  QI+DKFP  + GLKEL        FFL+K W D+   L++D    Y +S ++++S    I  +TK+C+F K +VE  +       N    F +   P+C+Y+   + +LK   +K  MNSVLENF++ Q V   +T E LLC+ Y+F V+  + G   H  YRL
Sbjct:   22 EELSETLDKPLENDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQVKLKDQAAKDKALQSMANMSSAQIISATAFQN--KMALQGLPRPPYPGSGGVSSVTEPFSQQ--------NYVMQTTGPPITGLYGYESTSGLTMSPSAPPWQGRSIASSKLRMLEFSAF-LEQPQ-DPENFNK----HLFVHIG----------QSNPTFSDPYLEAVDIRQIYDKFPEKKGGLKELFEKGPANAFFLVKFWADLSVNLQDDSSFFYGVSSQYESSDNMIITSSTKVCSFGKQVVEKVETEYARFENGRYVFRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTLETLLCVAYVFEVSTSEHGAQHHI-YRL 420          
BLAST of SD1 vs. TrEMBL
Match: H3DC39 (TEA domain-containing protein OS=Tetraodon nigroviridis OX=99883 PE=4 SV=1)

HSP 1 Score: 251.136 bits (640), Expect = 1.508e-74
Identity = 169/446 (37.89%), Postives = 234/446 (52.47%), Query Frame = 1
Query:  172 EEFGDN--FDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKES-------NVSTISEDG--QTIP--ETTQNINFKLMDNEYPFSN----PGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            EE GD     D  E   + +GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLAR+R +E        N+  +S+D   QT+    + Q ++  +M  + PF      PG V   Q   + D++      +T   T +P  I+ +            ++ P     +  +     + S       +K+ L E   F     + E          H F+H+GP SN S          LE I+  QI+DKF   + GLKEL        FFL+K W D+ S+  E     Y +S ++  +    I ++TK+C+F K +VE  +         +  F +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   ET+E LLC+ ++F V+  + G     QY +Y +V++
Sbjct:   17 EEAGDGEALADGSERGLDGEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKRVREYQSSIKAMNLDQVSKDKALQTVANLSSAQIVSASVMKPQTPFPPAVFWPGPVP-GQPGHSQDIKPFAQPPYTTLPTSHPAPISYEP-----------MSPPRPAAVTAPVWQDRTIAS-------SKLRLMEYSAFLETQKDRETYK-------HLFVHIGP-SNPS-----YSDPVLESIDVRQIYDKFSEKKGGLKELYEKGPRNAFFLVKFWADLSSDTEEGSGVFYGVSSQYSGTENITISVSTKVCSFGKQVVEKVETEYAHMEGGKYMFRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVSNRETQETLLCIAFVFEVSTSEHG----AQYHVYRLVDD 426          
BLAST of SD1 vs. TrEMBL
Match: U4U341 (TEA domain-containing protein OS=Dendroctonus ponderosae OX=77166 GN=D910_05696 PE=4 SV=1)

HSP 1 Score: 251.906 bits (642), Expect = 2.420e-74
Identity = 167/466 (35.84%), Postives = 243/466 (52.15%), Query Frame = 1
Query:  103 STAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEED--GVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDG------QTIP--ETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNI--LCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLG--PLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            ++ W  V   P D+   N   D++    +  D ++D A  D  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E       +        QT+    + Q ++   M ++   S PG   L   ++   + + G   F  P  +        S +     +      P+    +G++  L  +  V     I+ +K+ L E   F      +E     +    H F+H+G  PLS +  +LE         ++  QI+DKFP  + GLKEL        FFL+K W D+ S ++++    Y ++  ++++    I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   +T+E LLC  Y+F VA  + G     Q+ +Y +V +
Sbjct:   27 TSPWTPVPGPPGDS---NGGPDVKNLEVDLSDDEKDMAAADAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKLKVDHAVKEKTLQTMSGMSSAQIVSATSMHSK---SVPG---LPLGLNGHAMGFPGAAQFWQPGLQ-----PGPSQDVKPFAQGAYTGKPATAVSAGDVGPLQAAPPVWEGRAIATHKLRLVEFSGF------MESQSREEAYPKHLFVHIGGTPLSYTDPLLEA--------VDVRQIYDKFPEKKGGLKELYDKGPQTAFFLVKFWADLNSSIQDEAGAFYGVTSSYESNENMTITCSTKVCSFGKQVVEKVETEYAHYENGRFVYRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVSNRDTQETLLCTAYVFEVATGEHG----AQHHIYRLVKD 460          
BLAST of SD1 vs. Ensembl Cavefish
Match: ENSAMXT00000015527.2 (pep primary_assembly:Astyanax_mexicanus-2.0:8:25794338:25829633:1 gene:ENSAMXG00000015088.2 transcript:ENSAMXT00000015527.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 247.669 bits (631), Expect = 1.459e-76
Identity = 167/427 (39.11%), Postives = 229/427 (53.63%), Query Frame = 1
Query:  172 EEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVT--RNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVS--NLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            EE  +  D   E+ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E  V    +  +           K + N    S+   ++     + + L     +G + P      P SI   S     N        P  G +S + L  S          I+ +K+ + E   F ++ P  +P ++N+    H F+H+G  SN +         +LE ++  QI+DKFP  + GLKEL        FFL+K W D+   L++D    Y +S ++++S    I  +TK+C+F K +VE  +       N    F +   P+C+Y+   + +LK   +K  MNSVLENF++ Q V   +T E LLC+ Y+F V+  + G   H  YRL
Sbjct:   27 EELSEPLDKPLENDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKAREIQVKLKDQAAKD----------KALQNMATMSSAQIISATAFQNKMAL-----QGLSRPAVFFFRPFSIKPFSQQ---NYVMQATGPPITGYESASGLSMSPSAPPWQGRSIASSKLRMLEFSAF-LEQPQ-DPENFNK----HLFVHIGQ-SNPTY-----SDPYLEAVDIRQIYDKFPEKKGGLKELFEKGPANAFFLVKFWADLSVNLQDDSSFFYGVSSQYESSDNMIITSSTKVCSFGKQVVEKVETEYARFENGRYVFRIHRSPLCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTNRDTLETLLCVAYVFEVSTSEHGAQHHI-YRL 420          
BLAST of SD1 vs. Ensembl Cavefish
Match: tead1b (TEA domain transcription factor 1 [Source:NCBI gene;Acc:103039007])

HSP 1 Score: 244.588 bits (623), Expect = 1.695e-75
Identity = 165/454 (36.34%), Postives = 238/454 (52.42%), Query Frame = 1
Query:   97 MNSTAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDL------RWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            ++ ++W   SESP +        DIE   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E + S + +         Q +  K + +    S+   V+     + + L       + G  G   P +  P    K      + ++  +  + S G +S      +        I   K+ L E   F  +    +P  +N+    H F+H+G  ++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   ++E+    Y ++ ++++     I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G   H  YRL
Sbjct:    1 IDPSSWSG-SESPAE--------DIERMSDSADKPMDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREFH-SKLKD---------QTVKDKALQSMASMSSAQIVSATAIHNKLGLPGIPRPAFPGAAGVRRP-SGAPRYRIKPFAQQAYPIQPAVTTAISTGYESPAAPAPTVPAWQGRSIGTTKLRLVEFSAFLEQ--QRDPDSYNK----HLFVHIGQTNHS------YNDALLESVDIRQIYDKFPEKKGGLKELFGKGPQNSFFLIKFWADLNCNVQEETGAFYGVTSQYESPENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI-YRL 419          
BLAST of SD1 vs. Ensembl Cavefish
Match: tead1a (transcriptional enhancer factor TEF-1-like [Source:NCBI gene;Acc:103024231])

HSP 1 Score: 242.276 bits (617), Expect = 1.821e-74
Identity = 159/431 (36.89%), Postives = 227/431 (52.67%), Query Frame = 1
Query:  166 DIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDL------RWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            DIE   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E +          +    Q++  K + +    S+   V+     + + L       + G  GF    T +P S     +   +  + + I +   G +  ++   +        I   K+ L E   F  +    +P  +N+    H F+H+G  ++            LE ++  QI+DKFP  + GLK+L        FFL+K W D+   L+ED    Y ++ ++++     I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   ET+E LLC+  +F V+  + G   H  YRL
Sbjct:   15 DIERMSDSADKPMDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRELHAKL------KVTHLDQSVKDKALQSMAAMSSAQIVSATAIHNKLGLAGLPQPSFPGAPGFWQLSTGHPGS---SQDVKPFAQQAYPIQTALSGFEPPSVPAATPPAWQGRSIGTTKLRLVEFSSFLEQ--QRDPESYNK----HLFVHIGQTNHLH------SDPLLESVDIRQIYDKFPEKKGGLKDLFAKGPQNAFFLVKFWADLNCNLQEDSGAFYGVTSQYESPDNMTITCSTKVCSFGKQVVEKVETEYARFDNGRFVYKINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVSNRETQETLLCMACVFEVSNSEHGAQHHI-YRL 421          
BLAST of SD1 vs. Ensembl Cavefish
Match: tead1a (transcriptional enhancer factor TEF-1-like [Source:NCBI gene;Acc:103024231])

HSP 1 Score: 240.736 bits (613), Expect = 5.782e-74
Identity = 159/431 (36.89%), Postives = 226/431 (52.44%), Query Frame = 1
Query:  166 DIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDL------RWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            DIE   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E +               Q++  K + +    S+   V+     + + L       + G  GF    T +P S     +   +  + + I +   G +  ++   +        I   K+ L E   F  +    +P  +N+    H F+H+G  ++            LE ++  QI+DKFP  + GLK+L        FFL+K W D+   L+ED    Y ++ ++++     I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   ET+E LLC+  +F V+  + G   H  YRL
Sbjct:   15 DIERMSDSADKPMDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRELHAKL----------KDQSVKDKALQSMAAMSSAQIVSATAIHNKLGLAGLPQPSFPGAPGFWQLSTGHPGS---SQDVKPFAQQAYPIQTALSGFEPPSVPAATPPAWQGRSIGTTKLRLVEFSSFLEQ--QRDPESYNK----HLFVHIGQTNHLH------SDPLLESVDIRQIYDKFPEKKGGLKDLFAKGPQNAFFLVKFWADLNCNLQEDSGAFYGVTSQYESPDNMTITCSTKVCSFGKQVVEKVETEYARFDNGRFVYKINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVSNRETQETLLCMACVFEVSNSEHGAQHHI-YRL 417          
BLAST of SD1 vs. Ensembl Cavefish
Match: tead1a (transcriptional enhancer factor TEF-1-like [Source:NCBI gene;Acc:103024231])

HSP 1 Score: 234.572 bits (597), Expect = 4.149e-72
Identity = 157/425 (36.94%), Postives = 209/425 (49.18%), Query Frame = 1
Query:  166 DIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            DIE   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E +                 + F  +   +P S+       Q    I     G    + P    P           W  +   I +    TK   +   S +     P SYNK                           H F+H+G  ++            LE ++  QI+DKFP  + GLK+L        FFL+K W D+   L+ED    Y ++ ++++     I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   ET+E LLC+  +F V+  + G   H  YRL
Sbjct:   15 DIERMSDSADKPMDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRELHA---------------KLKFWQLSTGHPGSSQDVKPFAQQAYPIQTALSGFEPPSVPAATPP----------AW--QGRSIGT----TKLRLVEFSSFLEQQRDPESYNK---------------------------HLFVHIGQTNHLH------SDPLLESVDIRQIYDKFPEKKGGLKDLFAKGPQNAFFLVKFWADLNCNLQEDSGAFYGVTSQYESPDNMTITCSTKVCSFGKQVVEKVETEYARFDNGRFVYKINRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVSNRETQETLLCMACVFEVSNSEHGAQHHI-YRL 372          
BLAST of SD1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002687.1 (pep scaffold:Pmarinus_7.0:GL476762:168559:233001:1 gene:ENSPMAG00000002412.1 transcript:ENSPMAT00000002687.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 228.794 bits (582), Expect = 5.545e-70
Identity = 163/456 (35.75%), Postives = 231/456 (50.66%), Query Frame = 1
Query:  184 DNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQV---------------------LARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVAL-NQNMDAIDL---RWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGP------ISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQV                     LARR+ +E         G  + +TT+    + + N          A+ N+ M    L    +    GF           ++D    +         +   G +S   L   N     GP      I  +K+ L E   F  +A   +P  +N+    H F+H+G  SN +          LE ++  QI+DKFP  + GLKEL        FFL+K W D+ + ++E+    Y ++ +++++    I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LKQ  +K  MNSVLENF++ Q V   +T+E LLC+ Y+F V+  + G     Q+ +Y +V +
Sbjct:    6 DSVDKPMDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKMREFQTSIKVSSHIQVLARRKSREFQAKL---KGMNMDQTTKEKAMQSIANMSSAQIVSATAIHNKVMGLTALPQPSYPTATGFWPGALPGQPGSSQDIKPFVQQPYPLQAVAAIPGYESAAGL---NPPPGAGPAWQGRAIGTSKLRLVEFSAFLEQA--RDPDTFNK----HLFVHIG-QSNPAY-----SDPLLEAVDIRQIYDKFPEKKGGLKELYDKGPQEAFFLVKFWADLNTNIQEEAGAFYGVTSQYESAENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRIHRSPMCEYMINFIHKLKQLPEKYMMNSVLENFTILQVVTNRDTQETLLCVAYVFEVSTSEHG----AQHHIYKLVKD 437          
BLAST of SD1 vs. Ensembl Yeast
Match: TEC1 (Transcription factor targeting filamentation genes and Ty1 expression; Ste12p activation of most filamentation gene promoters depends on Tec1p and Tec1p transcriptional activity is dependent on its association with Ste12p; binds to TCS elements upstream of filamentation genes, which are regulated by Tec1p/Ste12p/Dig1p complex; competes with Dig2p for binding to Ste12p/Dig1p; positive regulator of chronological life span; TEA/ATTS DNA-binding domain family member [Source:SGD;Acc:S000000287])

HSP 1 Score: 58.5362 bits (140), Expect = 1.065e-9
Identity = 30/62 (48.39%), Postives = 42/62 (67.74%), Query Frame = 1
Query:  232 WSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQV 417
            WS  +E++F EAL +    G  KI + +    +GRNELI+ YIK +T + RT+KQ+SSHIQV
Sbjct:  132 WSEKVEEAFLEALRLIMKNGTTKIKIRNAN--FGRNELISLYIKHKTNEFRTKKQISSHIQV 191          
BLAST of SD1 vs. Ensembl Nematostella
Match: EDO36811 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHJ8])

HSP 1 Score: 238.81 bits (608), Expect = 2.634e-74
Identity = 159/413 (38.50%), Postives = 221/413 (53.51%), Query Frame = 1
Query:  217 EEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSH---GTKSGNILCQSNVVSNLGP--ISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            + +GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSH+QVLAR++ +E                   I  K+ D         R    Q M ++       +  +  V  N  S+   S +  +   N    SPS+      SG+    ++  +   P   S   + L E   F ++   L+P  +++    H F+HLG  +N S  L       LE ++  QI+DKFP  + GLK++        FFL+K W D+ + + ++    Y +S  +++S    I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LKQ  +K  MNSVLENF++ Q V   ET+E LLCL Y+F V+  + G   H  YRL
Sbjct:    4 DAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHLQVLARKKARE-------------------IQGKIKD------QAARDKALQTMASMS----SAQIVSASVLHNK-SMGTASMSAGYAAAN---ESPSYQRTSAFSGSPALAASPPTGATPWTTSRQPLRLVEFSAF-LEQQRLDPDTYHK----HLFVHLGHNTNFSDPL-------LEAVDIRQIYDKFPEKKGGLKDMYDKGPQAVFFLVKFWADLNTNIHDETGAFYGVSSTYESSENMTITCSTKVCSFGKQVVEKVETEYGHFENGRFVYRIHRSPMCEYMINFIHKLKQLPEKYMMNSVLENFTILQVVSNRETQETLLCLAYVFEVSTSEHGAQHHI-YRL 370          
BLAST of SD1 vs. Ensembl Nematostella
Match: EDO47339 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMG8])

HSP 1 Score: 128.257 bits (321), Expect = 4.520e-36
Identity = 56/76 (73.68%), Postives = 69/76 (90.79%), Query Frame = 1
Query:  214 AEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE 441
            AE +G+W+ DIEQSFQEALAIYPPCGR+KI+LS + KMYGRNELIARYI ++TGK RTRKQV+SHIQVLAR++ ++
Sbjct:    2 AEGEGLWAGDIEQSFQEALAIYPPCGRQKIMLSTKDKMYGRNELIARYILMKTGKMRTRKQVASHIQVLARKKIRQ 77          
BLAST of SD1 vs. Ensembl Medaka
Match: TEAD1 (TEA domain transcription factor 1 [Source:NCBI gene;Acc:101157846])

HSP 1 Score: 247.284 bits (630), Expect = 1.570e-76
Identity = 166/442 (37.56%), Postives = 227/442 (51.36%), Query Frame = 1
Query:  169 IEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKE--SNVSTISED----------------GQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARR+ +E  S +   S D                 Q +  T  +    L     P + PG   L Q M  I     G      P T+ P  I      TI + +     +P+     G              I  +K+ L E   F  +  + +  H       H F+H+G +++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   ++++    YR++ ++++S    I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G   H  YRL
Sbjct:    1 MERMSDSADKPVDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREFHSKLKVTSMDQAVKDKALQSMASMSSAQIVSATAIHNKLGLPGIPRP-AFPG-AGLWQGM--ISAGQPGSSQDIKPFTQQPYPIQPAVTTTISSYDPSAAPTPTAPAWQGR------------SIGTSKLRLVEFSAFLEQQRDPDSYH------KHLFVHIGQINHS------YSDALLESVDIRQIYDKFPEKKGGLKELYGRGPQNSFFLIKFWADLNCNIQDETGSFYRVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI-YRL 411          
BLAST of SD1 vs. Ensembl Medaka
Match: TEAD1 (TEA domain transcription factor 1 [Source:NCBI gene;Acc:101157846])

HSP 1 Score: 244.588 bits (623), Expect = 1.743e-75
Identity = 161/440 (36.59%), Postives = 229/440 (52.05%), Query Frame = 1
Query:  169 IEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVST-ISEDGQTIPE----------TTQNINFKLMDNEYPFSNPGRVA-----LNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLAR++ +E   +  ++   Q + +          + Q ++   + N+       R A     L Q M  I     G      P T+ P  I      TI + +     +P+     G              I  +K+ L E   F  +  + +  H       H F+H+G +++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   ++++    YR++ ++++S    I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G   H  YRL
Sbjct:    1 MERMSDSADKPVDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVTSMDQAVKDKALQSMASMSSAQIVSATAIHNKLGLPGIPRPAFPGAGLWQGM--ISAGQPGSSQDIKPFTQQPYPIQPAVTTTISSYDPSAAPTPTAPAWQGR------------SIGTSKLRLVEFSAFLEQQRDPDSYHK------HLFVHIGQINHS------YSDALLESVDIRQIYDKFPEKKGGLKELYGRGPQNSFFLIKFWADLNCNIQDETGSFYRVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI-YRL 411          
BLAST of SD1 vs. Ensembl Medaka
Match: tead3a (transcriptional enhancer factor TEF-5 [Source:NCBI gene;Acc:100049312])

HSP 1 Score: 241.891 bits (616), Expect = 1.349e-74
Identity = 159/419 (37.95%), Postives = 221/419 (52.74%), Query Frame = 1
Query:  223 DGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVST---ISEDG--QTIP--ETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            +GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLAR+R +E   S    +S+D   QT+    + Q ++  +M  + PF  P  +++     ++ L++        P  + P +            E                   +  V     I+  K+ L E   F     + E          H F+H+GP SN            LE I+  QI+DKF   + GLKEL     +  FFL+K W D+ S++ E     Y +S ++  +    I ++TK+C+F K +VE  +         +  F +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   ET+E LLC+ ++F V+  + G     QY +Y +VN+
Sbjct:   23 EGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKRVREYQASIKDQVSKDKALQTVANLSSAQIVSASVMKPQTPF--PASISI-----SLKLKFFRYLDSIKPFAQPPYTTLPTPVPAPIGYE---------ALPPPRPPTIAPPVWQDRTIASAKLRLLEYSAFMETQRDRETYK-------HLFVHIGP-SNP-----GYSDPVLESIDVRQIYDKFSEKKGGLKELYEKGPHNAFFLVKFWADLSSDVEEGSGVFYGVSSQYSGTENVTISVSTKVCSFGKQVVEKVETEYAHLDGGKYMFRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVSNRETQETLLCIAFVFEVSTSEHG----AQYHVYRLVND 408          
BLAST of SD1 vs. Ensembl Medaka
Match: tead3a (transcriptional enhancer factor TEF-5 [Source:NCBI gene;Acc:100049312])

HSP 1 Score: 241.891 bits (616), Expect = 1.979e-74
Identity = 166/450 (36.89%), Postives = 231/450 (51.33%), Query Frame = 1
Query:  130 SPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVST---ISEDG--QTIP--ETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            SP   Q  + N ++    D  D   +   E  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLAR+R +E   S    +S+D   QT+    + Q ++  +M  + PF  P  +++     ++ L++        P  + P +            E                   +  V     I+  K+ L E   F     + E          H F+H+GP SN            LE I+  QI+DKF   + GLKEL     +  FFL+K W D+ S++ E     Y +S ++  +    I ++TK+C+F K +VE  +         +  F +   PMC+Y+   + +LK   +K  MNSVLENF++ Q V   ET+E LLC+ ++F V+  + G     QY +Y +VN+
Sbjct:   11 SPDGAQEESGNGEV--LADGADRGLDGDPE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKRVREYQASIKDQVSKDKALQTVANLSSAQIVSASVMKPQTPF--PASISI-----SLKLKFFRYLDSIKPFAQPPYTTLPTPVPAPIGYE---------ALPPPRPPTIAPPVWQDRTIASAKLRLLEYSAFMETQRDRETYK-------HLFVHIGP-SNP-----GYSDPVLESIDVRQIYDKFSEKKGGLKELYEKGPHNAFFLVKFWADLSSDVEEGSGVFYGVSSQYSGTENVTISVSTKVCSFGKQVVEKVETEYAHLDGGKYMFRIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVSNRETQETLLCIAFVFEVSTSEHG----AQYHVYRLVND 423          
BLAST of SD1 vs. Ensembl Medaka
Match: TEAD1 (TEA domain transcription factor 1 [Source:NCBI gene;Acc:101157846])

HSP 1 Score: 239.58 bits (610), Expect = 1.913e-73
Identity = 160/455 (35.16%), Postives = 231/455 (50.77%), Query Frame = 1
Query:  169 IEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVST-ISEDGQTIP-ETTQNINFKLMDN---EYPFSNPGRVALNQNMDAIDLR------------------WGGVRGF--------TDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFP-LQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDK--YRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRL 1431
            +E   D+ D   ++ AE  GVWS DIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLAR++ +E   +  +S   Q +    ++  + KL D    +    +   ++  Q + A  +                   W G+             P T+ P  I      TI + +     +P+     G              I  +K+ L E   F  +  + +  H       H F+H+G +++S           LE ++  QI+DKFP  + GLKEL G      FFL+K W D+   ++++    YR++ ++++S    I  +TK+C+F K +VE  +       N    + +   PMC+Y+   + +LK   +K  MNSVLENF++   V   +T+E LLC+  +F V+  + G   H  YRL
Sbjct:    1 MERMSDSADKPVDNDAE--GVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREIQAAIKVSSHIQVLARRKSREFHSKLKDQAVKDKALQSMASMSSAQIVSATAIHNKLGLPGIPRPAFPGAGLWQGMISAGQPGSSQDIKPFTQQPYPIQPAVTTTISSYDPSAAPTPTAPAWQGR------------SIGTSKLRLVEFSAFLEQQRDPDSYHK------HLFVHIGQINHS------YSDALLESVDIRQIYDKFPEKKGGLKELYGRGPQNSFFLIKFWADLNCNIQDETGSFYRVTSQYESSENMTITCSTKVCSFGKQVVEKVETEYARFENGRFVYRISRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI-YRL 428          
BLAST of SD1 vs. Planmine SMEST
Match: SMESG000077205.1 (SMESG000077205.1)

HSP 1 Score: 939.873 bits (2428), Expect = 0.000e+0
Identity = 450/451 (99.78%), Postives = 451/451 (100.00%), Query Frame = 1
Query:   97 MNSTAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            MNSTAWDNVSESPKDNQAMNSNSDIE+FGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN
Sbjct:    1 MNSTAWDNVSESPKDNQAMNSNSDIEDFGDNFDDTDEDKAEEDGVWSADIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPGRVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINSPSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQPGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 451          
BLAST of SD1 vs. Planmine SMEST
Match: SMESG000021468.1 (SMESG000021468.1)

HSP 1 Score: 128.257 bits (321), Expect = 7.850e-32
Identity = 74/197 (37.56%), Postives = 105/197 (53.30%), Query Frame = 1
Query:  859 HEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSGLKELIGTYKNPCFFLLKIWIDMYSELREDDKYRISIKFKTSCPGKICLNTKICTFTKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMNSVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVNN 1449
            H F HL    +S      +G  FLE I  SQIWDK+P   GLKE         FF++K WIDM  ++        +I F+     K  L+TKIC+F + ++E  +       N    +  EN PMCDY++K +++L   K+   MNSVLENF++ QTV  A T EILLC+ +   V+  D G+    QY +Y ++ N
Sbjct:  292 HVFAHLNSTESS------LGHPFLEHIEISQIWDKYPETDGLKEYFERGPQDAFFMVKFWIDMNFDVLPQWNQLSTIIFEGVENVKSKLSTKICSFGRQVLERIEEQSPILENGISIYRFENVPMCDYMRKFIIKLSSLKEHSLMNSVLENFTILQTVTNAFTGEILLCIAFAMEVSISDQGS----QYHIYKLIRN 478          
The following BLAST results are available for this feature:
BLAST of SD1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TEAD12.104e-7335.39TEA domain transcription factor 1 [Source:HGNC Sym... [more]
TEAD11.003e-7235.41TEA domain transcription factor 1 [Source:HGNC Sym... [more]
TEAD37.113e-7135.06TEA domain transcription factor 3 [Source:HGNC Sym... [more]
TEAD32.164e-7035.06TEA domain transcription factor 3 [Source:HGNC Sym... [more]
TEAD24.152e-6735.16TEA domain transcription factor 2 [Source:HGNC Sym... [more]
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BLAST of SD1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
egl-441.230e-3681.58Transcription enhancer factor-like protein egl-44 ... [more]
egl-441.283e-3681.58Transcription enhancer factor-like protein egl-44 ... [more]
egl-441.551e-3681.58Transcription enhancer factor-like protein egl-44 ... [more]
egl-441.608e-3681.58Transcription enhancer factor-like protein egl-44 ... [more]
egl-443.861e-3681.58Transcription enhancer factor-like protein egl-44 ... [more]
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BLAST of SD1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sd2.573e-5332.95gene:FBgn0003345 transcript:FBtr0340115[more]
sd5.722e-4161.36gene:FBgn0003345 transcript:FBtr0074100[more]
sd5.722e-4161.36gene:FBgn0003345 transcript:FBtr0308132[more]
sd5.722e-4161.36gene:FBgn0003345 transcript:FBtr0074101[more]
sd5.722e-4161.36gene:FBgn0003345 transcript:FBtr0308130[more]
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BLAST of SD1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tead1a3.128e-7535.84TEA domain family member 1a [Source:ZFIN;Acc:ZDB-G... [more]
tead1b2.685e-7036.99TEA domain family member 1b [Source:ZFIN;Acc:ZDB-G... [more]
tead1b3.816e-7036.28TEA domain family member 1b [Source:ZFIN;Acc:ZDB-G... [more]
tead1b1.693e-6034.10TEA domain family member 1b [Source:ZFIN;Acc:ZDB-G... [more]
tead1b6.347e-5933.41TEA domain family member 1b [Source:ZFIN;Acc:ZDB-G... [more]
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BLAST of SD1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pik3ca6.462e-7436.16phosphatidylinositol-4,5-bisphosphate 3-kinase cat... [more]
pik3ca3.333e-7336.97phosphatidylinositol-4,5-bisphosphate 3-kinase cat... [more]
pik3ca3.531e-7336.73phosphatidylinositol-4,5-bisphosphate 3-kinase cat... [more]
pik3ca3.760e-7238.16phosphatidylinositol-4,5-bisphosphate 3-kinase cat... [more]
pik3ca1.357e-7137.07phosphatidylinositol-4,5-bisphosphate 3-kinase cat... [more]
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BLAST of SD1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tead11.806e-7235.02TEA domain family member 1 [Source:MGI Symbol;Acc:... [more]
Tead17.881e-7234.89TEA domain family member 1 [Source:MGI Symbol;Acc:... [more]
Tead17.881e-7234.89TEA domain family member 1 [Source:MGI Symbol;Acc:... [more]
Tead11.196e-7135.02TEA domain family member 1 [Source:MGI Symbol;Acc:... [more]
Tead41.086e-6735.78TEA domain family member 4 [Source:MGI Symbol;Acc:... [more]
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BLAST of SD1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P30051|TEAD1_MOUSE5.878e-7335.16Transcriptional enhancer factor TEF-1 OS=Mus muscu... [more]
sp|P28347|TEAD1_HUMAN1.011e-7235.39Transcriptional enhancer factor TEF-1 OS=Homo sapi... [more]
sp|P48984|TEAD4_CHICK7.787e-7135.65Transcriptional enhancer factor TEF-3 OS=Gallus ga... [more]
sp|Q90701|TEAD3_CHICK3.072e-7035.97Transcriptional enhancer factor TEF-5 OS=Gallus ga... [more]
sp|Q99594|TEAD3_HUMAN8.864e-7035.06Transcriptional enhancer factor TEF-5 OS=Homo sapi... [more]
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BLAST of SD1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
W8E2X60.000e+0100.00SD1 (Fragment) OS=Schmidtea mediterranea OX=79327 ... [more]
A0A4W4GMM85.123e-7639.39TEA domain-containing protein OS=Electrophorus ele... [more]
A0A4W4GMN83.220e-7538.79TEA domain-containing protein OS=Electrophorus ele... [more]
H3DC391.508e-7437.89TEA domain-containing protein OS=Tetraodon nigrovi... [more]
U4U3412.420e-7435.84TEA domain-containing protein OS=Dendroctonus pond... [more]
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BLAST of SD1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000015527.21.459e-7639.11pep primary_assembly:Astyanax_mexicanus-2.0:8:2579... [more]
tead1b1.695e-7536.34TEA domain transcription factor 1 [Source:NCBI gen... [more]
tead1a1.821e-7436.89transcriptional enhancer factor TEF-1-like [Source... [more]
tead1a5.782e-7436.89transcriptional enhancer factor TEF-1-like [Source... [more]
tead1a4.149e-7236.94transcriptional enhancer factor TEF-1-like [Source... [more]
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BLAST of SD1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000002687.15.545e-7035.75pep scaffold:Pmarinus_7.0:GL476762:168559:233001:1... [more]
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BLAST of SD1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
TEC11.065e-948.39Transcription factor targeting filamentation genes... [more]
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BLAST of SD1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO368112.634e-7438.50Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO473394.520e-3673.68Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SD1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TEAD11.570e-7637.56TEA domain transcription factor 1 [Source:NCBI gen... [more]
TEAD11.743e-7536.59TEA domain transcription factor 1 [Source:NCBI gen... [more]
tead3a1.349e-7437.95transcriptional enhancer factor TEF-5 [Source:NCBI... [more]
tead3a1.979e-7436.89transcriptional enhancer factor TEF-5 [Source:NCBI... [more]
TEAD11.913e-7335.16TEA domain transcription factor 1 [Source:NCBI gen... [more]
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BLAST of SD1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000077205.10.000e+099.78SMESG000077205.1[more]
SMESG000021468.17.850e-3237.56SMESG000021468.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30026965
GenBankAHJ60961.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026965 ID=SMED30026965|Name=SD1|organism=Schmidtea mediterranea sexual|type=transcript|length=1512bp
GGTTTACTGGACTAAAATAAATCAATAATAGTTTAATCTTAATTCAAATA
TTAAGAAGTTATAAATCCTTTCCATTCTGAATTTTTTGATCTTCAAATGA
ATTCAACAGCATGGGATAATGTTTCCGAGTCCCCGAAAGACAATCAAGCA
ATGAATAGCAATAGTGATATTGAAGAATTTGGAGATAATTTCGACGACAC
TGATGAAGATAAAGCTGAAGAGGATGGAGTTTGGTCGGCAGATATTGAAC
AGAGCTTTCAAGAAGCATTGGCGATTTATCCTCCATGTGGAAGACGAAAA
ATCATTTTGTCAGATGAGGGGAAAATGTACGGTCGCAATGAACTAATAGC
TCGATACATTAAATTACGTACCGGTAAAACGCGAACCAGAAAGCAGGTCT
CAAGTCACATTCAAGTATTAGCCAGAAGAAGGCATAAAGAGTCAAATGTG
TCTACAATCAGTGAAGACGGTCAGACTATACCAGAAACCACACAAAATAT
CAATTTTAAATTGATGGATAATGAGTACCCATTTTCTAACCCTGGACGAG
TTGCACTCAATCAAAATATGGATGCCATTGACTTAAGATGGGGTGGAGTG
CGCGGTTTTACAGATCCAGTAACAAGAAATCCTTTGTCCATTACCAAAGA
TTCCAATAATACAATATGGAATGTCGAAAATCATATGATCAATTCACCCT
CTCATGGTACAAAATCAGGAAATATTCTTTGTCAGTCAAATGTAGTCTCG
AATCTTGGGCCAATTTCTTATAATAAAATAGGGCTAAAAGAAATCATAGT
TTTTCAAGTTAAAGCTCCGAATTTGGAGCCTTGCCATTGGAATCAACCGG
GAAAAATTCATGAATTTATACACTTAGGTCCATTATCGAATTCTTCGGTT
ATGCTGGAAAATATTGGACCGACATTTTTAGAACCGATTAATGCCAGTCA
GATTTGGGATAAGTTTCCTTTACAAAGTGGACTTAAAGAATTAATTGGTA
CCTATAAGAATCCGTGCTTTTTTCTGTTAAAAATATGGATTGATATGTAT
TCCGAACTTCGAGAGGATGACAAATATAGGATATCTATCAAATTTAAAAC
GTCATGTCCCGGTAAAATTTGTTTGAACACCAAAATTTGCACATTTACCA
AAGCAATTGTAGAAGACAAGCAGATCATTGACCATTCCACTGCCAATGAT
GAAATGGGTTTCGTCGTTGAGAATTATCCCATGTGTGATTATCTCAAAAA
ACTGCTGGTTCGATTAAAACAGTTCAAAGACAAAGAAACCATGAATTCAG
TTTTAGAAAACTTCAGTGTTTTTCAAACTGTGCAAAAGGCTGAAACTGAA
GAAATTCTTCTTTGTTTAACATATTTATTTTCTGTTGCTGAACGAGATAG
TGGAAACGGGGGCCATTGTCAATATAGACTTTATAGTATTGTTAACAATT
AATTGTTATCATTCTATTTGTAATAATAATTGTAATATTTTATAATAGAC
TTTTCAAAAGCG
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protein sequence of SMED30026965-orf-1

>SMED30026965-orf-1 ID=SMED30026965-orf-1|Name=SMED30026965-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=452bp
MNSTAWDNVSESPKDNQAMNSNSDIEEFGDNFDDTDEDKAEEDGVWSADI
EQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQ
VSSHIQVLARRRHKESNVSTISEDGQTIPETTQNINFKLMDNEYPFSNPG
RVALNQNMDAIDLRWGGVRGFTDPVTRNPLSITKDSNNTIWNVENHMINS
PSHGTKSGNILCQSNVVSNLGPISYNKIGLKEIIVFQVKAPNLEPCHWNQ
PGKIHEFIHLGPLSNSSVMLENIGPTFLEPINASQIWDKFPLQSGLKELI
GTYKNPCFFLLKIWIDMYSELREDDKYRISIKFKTSCPGKICLNTKICTF
TKAIVEDKQIIDHSTANDEMGFVVENYPMCDYLKKLLVRLKQFKDKETMN
SVLENFSVFQTVQKAETEEILLCLTYLFSVAERDSGNGGHCQYRLYSIVN
N*
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Aliases
The feature 'SD1' has the following synonyms
Synonym
SD1
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0003700transcription factor activity, sequence-specific DNA binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005622intracellular
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0000136whole organism
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR041086YBD
IPR038096TEA/ATTS_sf
IPR000818TEA/ATTS_dom
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0035329hippo signaling
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000818TEA/ATTS domainPRINTSPR00065TEADOMAINcoord: 46..60
score: 84.89
coord: 94..108
score: 96.0
coord: 79..93
score: 95.11
IPR000818TEA/ATTS domainSMARTSM00426tea2coord: 37..108
e-value: 5.8E-48
score: 175.3
IPR000818TEA/ATTS domainPFAMPF01285TEAcoord: 43..108
e-value: 2.2E-26
score: 91.7
IPR000818TEA/ATTS domainPROSITEPS00554TEA_1coord: 79..107
IPR000818TEA/ATTS domainPROSITEPS51088TEA_2coord: 39..115
score: 29.046
NoneNo IPR availableGENE3DG3DSA:2.70.50.80coord: 223..450
e-value: 1.3E-52
score: 180.9
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..44
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 27..44
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..26
NoneNo IPR availablePANTHERPTHR11834TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATEDcoord: 9..445
NoneNo IPR availablePANTHERPTHR11834:SF6coord: 9..445
IPR041086YAP binding domainPFAMPF17725YBDcoord: 249..445
e-value: 2.5E-40
score: 138.6
IPR038096TEA/ATTS domain superfamilyGENE3DG3DSA:1.10.10.1610coord: 38..118
e-value: 2.2E-38
score: 132.2