Phospholipid-transporting ATPase

Query: 2128 SDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEID---------QENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGK------------TRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLL 3936
            S+++L   YE+ESPDE ALV  A  +   L++R  + V++  P   R +T+ +L  L FDS RKRMS++++ P TD I ++ KGADS +  +  +  S +D         +  T++Y++ YA  GLR L + +RV+SK+ ++ W + + EAE  L N+E+ L      +E+++ LLG +GIED LQDGV +TI  LR+AG+ +W+LTGDK+ETA+NIAY+ KL   ++ +I L+A+S+E    L+ + L  ++S       E  +GK            T     +  +L +DG +L +A+E  ++  FL LA+QC SV+C R+TP+QK+ +V+LV+  L+  TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ KF+YL+RLL++HG WCY++LA   LY FYK+T+++ L+FWFQF   FSAS MID    + FN+  + LPP++ GV D+D+ A+ L+ NP+LY++G N + Y+P  FW N+ DA +QS V + I Y+ +  S++ ++ +G  I   AL+T L+HLGIET+ WTW + +    S +L + V  +IY   C      S +PY  +   +   +F+L C++TP+AA+ PRL   +++  ++P  L
Sbjct:  687 SEREL--RYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVM-DLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTV-ALIYNASCATCYPPS-NPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQL 1304          

Query:   52 NLIPKKNGEEQCRKIYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA--------VKDDETDGQSDKVTMR 1371
            NL+P    E+                    A+N ++T KY  ++F+P NLFEQFHR AN+YFVFI +LNF+P + AF   +A  PV+F+L++TA +D  EDY R ++D ++NH  CL++S  +K++V + W     GDFV+L  NE  PADI+LL S+D  G+CHIET+NLDGE+NLK+R+VV    E  + F P +   S IE E PN ++ +F G I   +      L K NLLLRGCTLRNT+ V+GIV+YAG ETKA+LNN+  R+KRSKLERQ+N DV+WCVLLL+ + L  ++G+ +W      Q+    +  P S  + + +P   A  +F T +I  Q LIP+ LYV+ E VK  QV+ I +D+++YD E +  L+ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  + G +Y+         +  E D + ++V  R
Sbjct:   30 NLLPPPGAEDPAAGAAKGERRRRRGCAQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNP-LTFTSVIECEKPNNDLSRFRGCIIHDNGKKA-GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWR--YQEKKSLFYVPKSDGSSL-SPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPR 474          

Query: 2128 SDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEID---------QENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGK------------TRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLL 3936
            S+++L   YE+ESPDE ALV  A  +   L++R  + V++  P   R +T+ +L  L FDS RKRMS++++ P TD I ++ KGADS +  +  +  S +D         +  T++Y++ YA  GLR L + +RV+SK+ ++ W + + EAE  L N+E+ L      +E+++ LLG +GIED LQDGV +TI  LR+AG+ +W+LTGDK+ETA+NIAY+ KL   ++ +I L+A+S+E    L+ + L  ++S       E  +GK            T     +  +L +DG +L +A+E  ++  FL LA+QC SV+C R+TP+QK+ +V+LV+  L+  TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ KF+YL+RLL++HG WCY++LA   LY FYK+T+++ L+FWFQF   FSAS MID    + FN+  + LPP++ GV D+D+ A+ L+ NP+LY++G N + Y+P  FW N+ DA +QS V + I Y+ +  S++ ++ +G  I   AL+T L+HLGIET+ WTW + +    S +L + V  +IY   C      S +PY  +   +   +F+L C++TP+AA+ PRL   +++  ++P  L
Sbjct:  687 SEREL--RYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVM-DLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTV-ALIYNASCATCYPPS-NPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQL 1304          

Query:   52 NLIPKKNGEEQCRKIYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA--------VKDDETDGQSDKVTMR 1371
            NL+P    E+                    A+N ++T KY  ++F+P NLFEQFHR AN+YFVFI +LNF+P + AF   +A  PV+F+L++TA +D  EDY R ++D ++NH  CL++S  +K++V + W     GDFV+L  NE  PADI+LL S+D  G+CHIET+NLDGE+NLK+R+VV    E  + F P +   S IE E PN ++ +F G I   +      L K NLLLRGCTLRNT+ V+GIV+YAG ETKA+LNN+  R+KRSKLERQ+N DV+WCVLLL+ + L  ++G+ +W      Q+    +  P S  + + +P   A  +F T +I  Q LIP+ LYV+ E VK  QV+ I +D+++YD E +  L+ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  + G +Y+         +  E D + ++V  R
Sbjct:   30 NLLPPPGAEDPAAGAAKGERRRRRGCAQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNP-LTFTSVIECEKPNNDLSRFRGCIIHDNGKKA-GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWR--YQEKKSLFYVPKSDGSSL-SPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPR 474          

Query: 2059 TEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSA---MFGNFSKDISEIDQ------ENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNI--KSNYPNEIMEIRQGKTRPLIRKDLALS----VDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            TE    ++G+ + K +     P++       YE+ESPDE ALV  A  +   L  R P  V + +  +  P+T+ +L +LPFDS RKRMS++V+ P ++ ++++ KGADS    +    S D + +++      E T+ ++D YA+ GLR L + ++V+S   ++EW + +  AE  + N E+ LL     +E+ + LLG +GIED LQ+GV ++IE+L +AGI +W+LTGDK+ETA+NIAY+ KL   + +L  L+  SK+    L+   L  +  K+    E + + +   +P + +D  L     + G TL FA+++ ++  FL L   C +VVC R TP+QK+E+V+LV+ +L++ TLAIGDGANDVSMIQ+AD+G+G+ G EGMQAVMASDFA+++FK+L +LLLVHG WCY +L+   LY FYK+  Y+ L+FW+QF   FS + M D    + FN+  T  PP+IYGV +KD+ A+TLM+ PELYR+G   ++Y P  FW+ +LDA +QS V + + Y T+  SD  I+ FG  +   AL   L+HL IE++  TW H L + I  IL++ +F +++  +C  V C    +PY  + ++M   +F+L+C++T   A+ PR     ++ SL+P+ + + 
Sbjct:  695 TEKQHGDAGLLNGKAESLPGQPLACN---LCYEAESPDEAALVYAARAYQCTLRSRTPEQVMV-DFAALGPLTFQLLHILPFDSVRKRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKELQKKTQALPEQVSLSEDLLQPPVPRDSGLRAGLIITGKTLEFALQESLQKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQGSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIH-LLVIIGSILSYFLFAIVFGAMC--VTCNPPSNPYWIMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQGSLFPSPILRA 1332          

Query:   61 PKKNGEEQCRKIYPSTST-NSNFEKYK--YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQS--DKVTMRSEFGDT 1389
            PK +G    R + P        +EK+   Y NN +RT KY  + F+P NLFEQFHR AN+YF+F+++LN++P +EAF KE+  +P+V VL++ AIKD +EDYR++K D+++N+    +YS  +K+++++ W     GDF++L  NE IPAD+VLL S D  GICHIETS LDGESNLKQR+VV    E ++   PE  S S IE E+PN ++ +F G     S    + L K NLLLRGCT+RNTE V+GIVVYAG ETKAMLNN+  R+KRSKLER+ N DV+WCV+LL+I+CL+ ++G+ IW ++ + +  + ++  P+    +I +P +  F  FWT +I  Q LIP+ LYV+ E VK+ Q++ I+ D++ Y+ + +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  + G DY  +++    +S  + V+   +F DT
Sbjct:   44 PKLSGRH--RIVVPHIQPFKDEYEKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFS-SRIECESPNNDLSRFRG-FLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIW-LSRYEK--MHFFNVPEPDGHII-SPLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRLESYQEAVSEDEDFIDT 485          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFG-----------NFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKS----NYPN-EIMEIRQGKTRPLIRKDL-----ALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSD-DPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            YE+ESPDE ALV  A  + + L+ R P  VT+  P+    +T+++L  L FDS RKRMS++V+ P T  I+++ KGADS +             N  K + +I +  T+ ++D YAR GLR L + ++V+S++ F  W    +EAE  L N ++ L+     +E+ + LLG +GIED LQ+GV DTI +LR AGI +W+LTGDK+ETA+NIA+S +L ++   +  ++  ++E    ++   L  +K       P+ ++   R     P I  +       L +DG TL    + +++  FL L + C SV+C R+TP+QK+ IV+LV++ LR+ TL+IGDGANDVSMIQ AD+G+GI G EGMQAVM+SDFA+T+FK+LK+LLLVHG WCY++LAR  +Y  YK+  Y+ L+FW+QF   FS+S MID    + FN+  T LPP+++GV DKD+ A+TL+  PELY++G N + Y    FW++++DA +QS + + I Y+ +  SDI ++ FG  I   +L T L+H  +E + WT FHG+ +  SF++ +LV +++Y   C  V+C S  +PY  +   +    F+L+C +TP+ A+ PR    +++ +   +L+ K 
Sbjct:  689 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGT-CLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKI-RARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLV-SLLYNATC--VICNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKA 1303          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKF--PDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA----------VKDDETDGQ---------------SDKVTMRSEFGDTDDKK-------MNDDHGKKLL-----------------------KNLIPMLH---------GDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPV 1578
            +  N+++T KY  ++F+P N+FEQ HRFAN+YFV I +LNF+P + AF  EV+ IP+  +L+VTAIKDA ED RR+K+D+ +N+ +CLIYS  ++ +V++ W   R GDF+++  NE +PADI+LL S+D +GICH+ET++LDGE+NLKQR VV    +    F+PE+  N+ +  E PN  + KF G +    Q+        +LLLRGCT+RNTE  +GIV+YAG ETKAMLNN+  R+KRSK+ER++N D+ +C+ +LI++CL  ++G+ IW  T     F E+  F  PD+  + + + A+  F  F T +I  Q LIP+ LYV+ E VK+ QVF +  DL++YD E +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  I G +Y+           K+ ++DG+                D  TMRS+ G    ++       +   + ++ +                       KNL+  +           D    +  +S   ++ DFFL + ICN+ +VS     +  V
Sbjct:   38 HRGNQIKTSKYTVLSFVPKNIFEQLHRFANLYFVGIAVLNFIPVVNAFQPEVSMIPICVILAVTAIKDAWEDLRRYKSDKVINNRECLIYSRKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIV-CEKPNNHLNKFKGYMEHPDQT-RTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGT-----FEEHPPFDVPDANGSFLPS-ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQYQCLSFSARWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQPPVAFSSSIEKDVTPDKNLLTKVRDAALWLETLSDSRPAKASLSTTSSIADFFLALTICNSVMVSTTTEPRQRV 577          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFG-----------NFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKS----NYPN-EIMEIRQGKTRPLIRKDL-----ALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSD-DPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            YE+ESPDE ALV  A  + + L+ R P  VT+  P+    +T+++L  L FDS RKRMS++V+ P T  I+++ KGADS +             N  K + +I +  T+ ++D YAR GLR L + ++V+S++ F  W    +EAE  L N ++ L+     +E+ + LLG +GIED LQ+GV DTI +LR AGI +W+LTGDK+ETA+NIA+S +L ++   +  ++  ++E    ++   L  +K       P+ ++   R     P I  +       L +DG TL    + +++  FL L + C SV+C R+TP+QK+ IV+LV++ LR+ TL+IGDGANDVSMIQ AD+G+GI G EGMQAVM+SDFA+T+FK+LK+LLLVHG WCY++LAR  +Y  YK+  Y+ L+FW+QF   FS+S MID    + FN+  T LPP+++GV DKD+ A+TL+  PELY++G N + Y    FW++++DA +QS + + I Y+ +  SDI ++ FG  I   +L T L+H  +E + WT FHG+ +  SF++ +LV +++Y   C  V+C S  +PY  +   +    F+L+C +TP+ A+ PR    +++ +   +L+ K 
Sbjct:  717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGT-CLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKI-RARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLV-SLLYNATC--VICNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKA 1331          

Query:   82 QCRKIYPSTST-NSNFEKY--KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKF--PDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA----------VKDDETDGQ---------------SDKVTMRSEFGDTDDKK-------MNDDHGKKLL-----------------------KNLIPMLH---------GDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPV 1578
            Q R ++P+ S  + ++E+   +Y  N   T KY   TF+P NLFEQFHR+AN+YF+F++ILN++P +E F +E+  +P+  VL V  IKD +ED++R + D+ +N S   IY   ++ +V++ W   R GDF+++  NE +PADI+LL S+D +GICH+ET++LDGE+NLKQR VV    +    F+PE+  N+ +  E PN  + KF G +    Q+        +LLLRGCT+RNTE  +GIV+YAG ETKAMLNN+  R+KRSK+ER++N D+ +C+ +LI++CL  ++G+ IW  T     F E+  F  PD+  + + + A+  F  F T +I  Q LIP+ LYV+ E VK+ QVF +  DL++YD E +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  I G +Y+           K+ ++DG+                D  TMRS+ G    ++       +   + ++ +                       KNL+  +           D    +  +S   ++ DFFL + ICN+ +VS     +  V
Sbjct:   44 QQRVVFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIV-CEKPNNHLNKFKGYMEHPDQT-RTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGT-----FEEHPPFDVPDANGSFLPS-ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQYQCLSFSARWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQPPVAFSSSIEKDVTPDKNLLTKVRDAALWLETLSDSRPAKASLSTTSSIADFFLALTICNSVMVSTTTEPRQRV 605          

Query: 2095 FKNDQDNKCPISDKDLLAS-----YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVK-CPQTDNIIMFCKGADSAMFGNFSKDISEIDQE-----NTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYT--VICGKVVCGSDDPYDFI-FQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPN 3930
            F+   D +   S +  +A      Y+SESPDE+ALV+ A  +G +LL+R  + V ++   S   + Y VL  LPFD++RKRMS+I++       II+  KGAD+ +    S+  S   +       +++++  YA+ GLR L +  ++ +++ +  W ++++EAE  + + E  L   T   E D+ LLGV+ IED LQDGV + I SLR AGI VW+LTGDK ETA+NIAYS++LFS +  L+ + A+      DL+ E L  I   Y     E+              L ++ ST+++ ++      F+ L   C SV+C R TP+QKA++V L K +L+ + LAIGDGANDVSMIQ ADVG+G+ G EGMQAVM+SDFAM +F++L  LLLVHG W Y +LA+T LY FYK+ + + ++FW+Q  N FSA + IDP+  +++N+  T +PP+++G  D+D  A+ L+  P LY  G   K Y+ + FW+N+LDA+WQS V++ ICY T+  S++ +W FG ++    +I    HL +  ++WTW     +F+S +L + +  ++Y   V          DP   +  ++     FW+  +++ +  + PR  + T+ N++ P+
Sbjct:  742 FRRSVDKRSSSSTETAVAPPLHSFYDSESPDELALVEAAREYGIRLLRRRFDDVIVYLRHSTSSVKYKVLHTLPFDADRKRMSVIIRESSGLKRIIVLTKGADATVIPVLSEAFSTSARGEEVIFKSQEHLTQYAKEGLRTLCLSMKIWTEEEYQGWKEKHEEAELDMMDKETMLAESTLRAEQDLELLGVTAIEDRLQDGVPECIHSLREAGIRVWVLTGDKIETAVNIAYSSRLFSPSMDLLNIGANGVRAVSDLLTEHLKRIARAY-----EVSADAA-----DSFGLVLNASTMSYCLDPHNLERFVKLLRGCRSVLCCRATPLQKAQLVNLAKNHLKGKVLAIGDGANDVSMIQGADVGIGLSGQEGMQAVMSSDFAMARFRFLSNLLLVHGHWNYYRLAQTILYFFYKNAMLVFVIFWYQIFNGFSAQVPIDPVYLMVYNLIFTSVPPLLFGCLDQDASAELLLDCPRLYEQGRLGKRYRWYSFWINMLDAVWQSLVVFFICYFTYRGSNVDMWTFGHLLVTQLIIVNTFHLALFVQYWTWPMFWSMFLS-VLLFFICALLYNGFVTANWTWTNVKDPPSMVSLKSFSSLEFWMALIISVVLCLTPRYVLTTVVNTVSPS 1356          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLS----NSFIEVENPNQEIYKFNGTIFFKSQSIGIT-----LRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKF--PDSI------PTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKD--DETDGQSDKV--TMRSEFGDTDDKKMN-------DDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKD----FFLLMGICNTTVVSLNKNE 1566
            KY  N + T KY+ +TFIP NLFEQ HR AN+YF+FI+ILN +  I AFGK ++ +P+ FVL +TAIKDA EDYRR+K+DQ++NHS C ++  +++++ + +W +   GDFV L  +E IPADI+LL S+D++G+C++ET NLDGESNLKQR+ +  M + +N   P   S    N  I  E P  ++YKF G +        +      L K N+LLRGC ++NT+ V GIV+YAGK+TKAMLNNN  R+KRS LE+  N D++W V  L+ LC+  ++ + +W  T  T   + +  F  P+S            +P+ +++ +FW+ +I  Q +IP+ LYV+ EF+K+ QV+ + +D  MY ++ +K L+ RA NI E+LGQIQYV  DKTGTLTEN+M F+R  ++G+DY  +   D  D   + V  T+RS+     +KK+            ++L  +  P L    ++    +    ++ D    FFL M ICNT VV+   +E
Sbjct:  102 KYCGNRISTTKYSVLTFIPKNLFEQLHRAANLYFIFIVILNMI--IGAFGKYISVLPIAFVLGITAIKDAFEDYRRYKSDQKINHSTCRVWDASQQRYRKLEWQNILVGDFVHLSHDEIIPADILLLRSSDVNGVCYVETCNLDGESNLKQRQAIRSMGKYHNANVPLEYSPAEFNYRIACEQPTTDVYKFEGRLEAIEGGPPLAREFTILAKENVLLRGCVVKNTDFVEGIVLYAGKDTKAMLNNNGPRYKRSSLEKMTNVDILWSVCTLLALCVIGAVLSGVWLRTFSTPYIVPFLVFIHPNSSYHNNNDSQYKYSPSYESWFSFWSYIIVLQVMIPISLYVSIEFIKIFQVWFMSQDRNMYYDKVDKRLQCRALNITEELGQIQYVMSDKTGTLTENQMVFRRCSVNGNDYGGRPVVDAVDSSLELVASTLRSD--QPTEKKLQMAALAEAAAKTRRLRPSRDPALES--QLASSVLKLGADIDDPVFAFFLTMAICNTVVVNAKPHE 606          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQ-ENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYK-EAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRL--IELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAE---QCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSL 3921
            YE+ESPDE+AL++ A ++ Y LL+R    VTI  PE      Y +L  LPFD+ RKRMS+IV   +    +M+CKGADSA+    S D  E  + ++ KD++D YA+ GLR L    + ISK+ F ++   Y+   E      EK L     E+E+++ L GV+GIED LQDGV DT+ +LR AGI VW+LTGDK ETA NIA S+ LF   + L  IE    ++E +           +S   N IM              + L+ DG+               HL E   +  +V+C R TP +KA IV  VK+ ++   LAIGDGANDV MIQ A VG+GI G EG+QA MA DFA+ +FK+L RLLLVHG W Y +LA T LY  YK+   + ++F++QF N  S + ++DP+  V++ I  T + P++ GV D+D    TLM  PELY  G   + Y   HF+ +++D I+Q++VIY + Y+T  +S   +WE G  I   +++    HL ++ R+W W   L    SF + +         +        D P       M    FW    +T + A+ PR T   + +SL
Sbjct:  649 YEAESPDELALIEGAALYDYVLLERAATSVTISTPEKAE-KRYEILLTLPFDATRKRMSVIVNSQK--GPLMYCKGADSAIISRLSSDSLESKRVQDLKDHLDNYAKKGLRTLCFAMKYISKEDFEDFLDSYRFLMEDATSEREKMLSEKADELETNLKLSGVTGIEDRLQDGVPDTLRALRDAGIQVWVLTGDKLETAQNIATSSGLFHPQRSLKVIETETDAEEAS-----------ESAGLNIIMS----------PAAIRLAQDGNA--------------HLMEALKKAKTVLCYRMTPSEKATIVNTVKKRIKGNVLAIGDGANDVPMIQAAHVGIGIAGKEGLQAAMACDFAIARFKFLSRLLLVHGHWSYYRLANTFLYFLYKNANAVFIIFYYQFYNGASGTNIVDPIWGVIYPIIFTSVQPVVVGVLDQDYDDQTLMNKPELYVIGRENQLYTWKHFFRDVIDGIYQAAVIYYVAYLTLDNSTSSLWEMGFYIATSSILVNSGHLALQVRYWHW--QLVALFSFFILFNFAFFFAECLTAAAAMVPDPPVWMPIHAMGDPRFWYYQFITVIVALCPRFTSMCLMSSL 1205          

Query:   64 KKNGEEQCRKIYPSTSTNSNFEKYKY--------ANNEVRTQKYNAITFIPINLFEQFH-RFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMM-----ENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRN---PAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETD 1344
            + N E   R I P    N  FE  +Y         +N + T KY    FIP+N++ Q   ++AN+YF+FI ILN++P  +A+ + V  IP+ FVL  T IKD +EDYRR+K D ++N   C ++   +  F + +W     GDFV +  N+ +PADI+LL S+  SG C+IET NLDGE++LKQR V        + ++TFKP   +   +  E P++ IY     + F+     + + K N+LLRG  ++NT  V GIVVYAG +TK M NN     K S +E+  NK +I C ++L+++ L  +I + +W         +  +   + IP ++ N   P ++ F+      I YQ L+P+ LY+T E +K  Q++ I  D+++YD ++++ ++ R+ +IPE+LG + +V  DKTGTLTEN M F+    D  DY     +++
Sbjct:   34 RSNRETGSRVIRP----NHLFESPRYELNNYRDFTDNRISTTKYTFWNFIPLNIWHQVSTKYANLYFIFIAILNWVPFFDAYTRYVGLIPICFVLGTTLIKDGIEDYRRYKFDNQINKKTCHVWDRDRCAFRKTEWRYILVGDFVHISNNQDVPADIILLRSSSESGTCYIETCNLDGETSLKQRMVPAKVIDYSKKDSTFKPPDFTG-VVTCEKPDKSIYTIRAKVEFEPGQSDVII-KENMLLRGSRIKNTTFVEGIVVYAGHDTKVMQNNGRAPHKTSGIEKLTNKFIIACFIMLLLMVLYGAITSAVW---------VGQHPVDEQIPFILSNTPRPFIEGFIGIGAFFINYQLLVPISLYITVEIIKALQIYFISNDIQLYDQKSDRAIDCRSLSIPEELGTVTHVLSDKTGTLTENMMIFRNCAFDETDYGSNGSQSN 462          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQ-ENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYK-EAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRL--IELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAE---QCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTI 3900
            YE+ESPDE+AL++ A ++ Y LL+R    VTI  PE      Y +L  LPFD+ RKRMS+IV   +    +M+CKGADSA+    S D  E  + ++ KD++D YA+ GLR L    + ISK+ F ++   Y+   E      EK L     E+E+++ L GV+GIED LQDGV DT+ +LR AGI VW+LTGDK ETA NIA S+ LF   + L  IE    ++E +           +S   N IM              + L+ DG+               HL E   +  +V+C R TP +KA IV  VK+ ++   LAIGDGANDV MIQ A VG+GI G EG+QA MA DFA+ +FK+L RLLLVHG W Y +LA T LY  YK+   + ++F++QF N  S + ++DP+  V++ I  T + P++ GV D+D    TLM  PELY  G   + Y   HF+ +++D I+Q++VIY + Y+T  +S   +WE G  I   +++    HL ++ R+W W   L    SF + +         +        D P       M    FW    +T + A+ PR +I
Sbjct:  649 YEAESPDELALIEGAALYDYVLLERAATSVTISTPEKAE-KRYEILLTLPFDATRKRMSVIVNSQK--GPLMYCKGADSAIISRLSSDSLESKRVQDLKDHLDNYAKKGLRTLCFAMKYISKEDFEDFLDSYRFLMEDATSEREKMLSEKADELETNLKLSGVTGIEDRLQDGVPDTLRALRDAGIQVWVLTGDKLETAQNIATSSGLFHPQRSLKVIETETDAEEAS-----------ESAGLNIIMS----------PAAIRLAQDGNA--------------HLMEALKKAKTVLCYRMTPSEKATIVNTVKKRIKGNVLAIGDGANDVPMIQAAHVGIGIAGKEGLQAAMACDFAIARFKFLSRLLLVHGHWSYYRLANTFLYFLYKNANAVFIIFYYQFYNGASGTNIVDPIWGVIYPIIFTSVQPVVVGVLDQDYDDQTLMNKPELYVIGRENQLYTWKHFFRDVIDGIYQAAVIYYVAYLTLDNSTSSLWEMGFYIATSSILVNSGHLALQVRYWHW--QLVALFSFFILFNFAFFFAECLTAAAAMVPDPPVWMPIHAMGDPRFWYYQFITVIVALCPRQSI 1198          

Query:   64 KKNGEEQCRKIYPSTSTNSNFEKYKY--------ANNEVRTQKYNAITFIPINLFEQFH-RFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMM-----ENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRN---PAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDG----QSDKVTMR 1371
            + N E   R I P    N  FE  +Y         +N + T KY    FIP+N++ Q   ++AN+YF+FI ILN++P  +A+ + V  IP+ FVL  T IKD +EDYRR+K D ++N   C ++   +  F + +W     GDFV +  N+ +PADI+LL S+  SG C+IET NLDGE++LKQR V        + ++TFKP   +   +  E P++ IY     + F+     + + K N+LLRG  ++NT  V GIVVYAG +TK M NN     K S +E+  NK +I C ++L+++ L  +I + +W         +  +   + IP ++ N   P ++ F+      I YQ L+P+ LY+T E +K  Q++ I  D+++YD ++++ ++ R+ +IPE+LG + +V  DKTGTLTEN M F+    D  DY     +++     +SD++  R
Sbjct:   34 RSNRETGSRVIRP----NHLFESPRYELNNYRDFTDNRISTTKYTFWNFIPLNIWHQVSTKYANLYFIFIAILNWVPFFDAYTRYVGLIPICFVLGTTLIKDGIEDYRRYKFDNQINKKTCHVWDRDRCAFRKTEWRYILVGDFVHISNNQDVPADIILLRSSSESGTCYIETCNLDGETSLKQRMVPAKVIDYSKKDSTFKPPDFTG-VVTCEKPDKSIYTIRAKVEFEPGQSDVII-KENMLLRGSRIKNTTFVEGIVVYAGHDTKVMQNNGRAPHKTSGIEKLTNKFIIACFIMLLLMVLYGAITSAVW---------VGQHPVDEQIPFILSNTPRPFIEGFIGIGAFFINYQLLVPISLYITVEIIKALQIYFISNDIQLYDQKSDRAIDCRSLSIPEELGTVTHVLSDKTGTLTENMMIFRNCAFDETDYGSNGSQSNPDKPVKSDELYQR 475          

Query: 2122 PISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLI-----------ELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQ---------GKTRPLIRKDL-------------ALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSS------DIGIWEFGQIITACALITCLV-HLGIETRFWTWFHGLGIFISFILAWLVFTMIY--TVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLGK 3972
            P  DK  L  Y+++SPDE AL   A   GY    R P  +TI    +E   T+ +L +L F+++RKRMS+IVK P    I ++CKGAD  +        S+I + +T  ++  +A +GLR L +G + +   YFS+W  R K+A   + + E  + +L  EIE D++L+G + IED LQDGV + I  L  A I +W+LTGDK ETAINIAYS +L ++  + I           E+       T + I      +      EI  I +            R ++  DL             AL ++G +L FA+   ++  FL +A  C +V+C R TP+QKA++V LVK N +  TL+IGDGANDVSMI+ A +GVGI G EGMQAV+ASD+++ +FKYL+RLLLVHG W Y ++A+   Y FYK+  + L  FW+ F   +SA  + D +    +N+  T LP +  G  D+D+     +R P+LY  G     +    F  ++L  ++ S VI+ I Y  F ++      D+  +      T  AL+  +   +  +T +WT      I+ S +L +LV  ++Y    +   V   S   Y   F+ M    FW   ++  +  + P +         +P+   +  IR +K+GK
Sbjct:  497 PERDKGQLV-YQAQSPDEHALTSAARNFGYVFRARTPQSITIEVMGNEE--THELLAILDFNNDRKRMSVIVKGPD-GKIRLYCKGADMMIMQRIHPSTSQIMRTSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEEIEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVVVDGQTDTEVEVQLKDTRNTFEQILALPSPLGGKPRIEIETIHEESEAISSARSMDRNIVTPDLKSAEMAEHESGGVALVINGDSLAFALGPRLERTFLEVACMCNAVICCRVTPLQKAQVVDLVKRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYIRMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDHYSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFTTFTALVVVVTGQIAFDTSYWTAISHFVIWGSLVLYFLVCFLLYEWLPVSWIVKTSSSISYGVAFRTMVTPHFWFSILMVSVVLLLPVMLNRFFWLDTHPSFADRLRIR-KKMGK 1150          

Query:  130 KYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVM--MENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTV----IRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAF--NIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHG---------KKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNE 1566
            ++KYA+N ++T KYN ITFIP NLFEQF R AN YF+ ++IL F+P+I +       +P+V VL+ +AIKD  +D +R  +D+ VN  K   Y        E+ WS+ + GD +++ +N+ + AD++LL +++  G+C IET  LDGE+NLK R  +    E  +        +  I  E PN ++ KFNG + + +   G+    +N+LLRGC L+NT    G+VV+AGK+TK M+N+  T+FKR+ L+R +N  ++  VL LI +CL C+I   +W   +  + F  Y  + D +P+      R  A+ AFL F++ +I    ++P+ LYV+ E ++      I  D +MY    EK +  +A    + E+LGQ+QYVF DKTGTLT N M F +  I+G  Y           D    + E  +T+DK  + D           K   KNL+          +    ++  +  F+ L+ +C+T +   +K +
Sbjct:   33 QFKYADNVIKTSKYNIITFIPQNLFEQFQRIANFYFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGRKS--YVVRNGSLCEEDWSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMGDDLDGITRFDGEIICEPPNNKLDKFNGKLIWNNHEYGVN--NDNILLRGCILKNTRWCYGVVVFAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWEYQT-GRYFTIYLPWDDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGEKSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISYG----------DIYDHKGEVIETNDKTKSLDFSWNSASEPTFKFFDKNLV----------DATKRQVPEIDQFWRLLALCHTVMPERDKGQ 503          

Query: 2122 PISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLI-----------ELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQ---------GKTRPLIRKDL-------------ALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSS------DIGIWEFGQIITACALITCLV-HLGIETRFWTWFHGLGIFISFILAWLVFTMIY--TVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLGK 3972
            P  DK  L  Y+++SPDE AL   A   GY    R P  +TI    +E   T+ +L +L F+++RKRMS+IVK P    I ++CKGAD  +        S+I + +T  ++  +A +GLR L +G + +   YFS+W  R K+A   + + E  + +L  EIE D++L+G + IED LQDGV + I  L  A I +W+LTGDK ETAINIAYS +L ++  + I           E+       T + I      +      EI  I +            R ++  DL             AL ++G +L FA+   ++  FL +A  C +V+C R TP+QKA++V LVK N +  TL+IGDGANDVSMI+ A +GVGI G EGMQAV+ASD+++ +FKYL+RLLLVHG W Y ++A+   Y FYK+  + L  FW+ F   +SA  + D +    +N+  T LP +  G  D+D+     +R P+LY  G     +    F  ++L  ++ S VI+ I Y  F ++      D+  +      T  AL+  +   +  +T +WT      I+ S +L +LV  ++Y    +   V   S   Y   F+ M    FW   ++  +  + P +         +P+   +  IR +K+GK
Sbjct:  532 PERDKGQLV-YQAQSPDEHALTSAARNFGYVFRARTPQSITIEVMGNEE--THELLAILDFNNDRKRMSVIVKGPD-GKIRLYCKGADMMIMQRIHPSTSQIMRTSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEEIEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVVVDGQTDTEVEVQLKDTRNTFEQILALPSPLGGKPRIEIETIHEESEAISSARSMDRNIVTPDLKSAEMAEHESGGVALVINGDSLAFALGPRLERTFLEVACMCNAVICCRVTPLQKAQVVDLVKRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYIRMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDHYSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFTTFTALVVVVTGQIAFDTSYWTAISHFVIWGSLVLYFLVCFLLYEWLPVSWIVKTSSSISYGVAFRTMVTPHFWFSILMVSVVLLLPVMLNRFFWLDTHPSFADRLRIR-KKMGK 1185          

Query:  130 KYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVM--MENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTV----IRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAF--NIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHG---------KKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNE 1566
            ++KYA+N ++T KYN ITFIP NLFEQF R AN YF+ ++IL F+P+I +       +P+V VL+ +AIKD  +D +R  +D+ VN  K   Y        E+ WS+ + GD +++ +N+ + AD++LL +++  G+C IET  LDGE+NLK R  +    E  +        +  I  E PN ++ KFNG + + +   G+    +N+LLRGC L+NT    G+VV+AGK+TK M+N+  T+FKR+ L+R +N  ++  VL LI +CL C+I   +W   +  + F  Y  + D +P+      R  A+ AFL F++ +I    ++P+ LYV+ E ++      I  D +MY    EK +  +A    + E+LGQ+QYVF DKTGTLT N M F +  I+G  Y           D    + E  +T+DK  + D           K   KNL+          +    ++  +  F+ L+ +C+T +   +K +
Sbjct:   68 QFKYADNVIKTSKYNIITFIPQNLFEQFQRIANFYFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGRKS--YVVRNGSLCEEDWSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMGDDLDGITRFDGEIICEPPNNKLDKFNGKLIWNNHEYGVN--NDNILLRGCILKNTRWCYGVVVFAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWEYQT-GRYFTIYLPWDDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGEKSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISYG----------DIYDHKGEVIETNDKTKSLDFSWNSASEPTFKFFDKNLV----------DATKRQVPEIDQFWRLLALCHTVMPERDKGQ 538          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNF---SKDISE-IDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKM--DFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPN 3930
            YE+ESPDE+ALV  A  +   LL R PN + +  P +     Y +L+VLPFDS+RK MSI+V+   +  I+++ KGADS++       S +  E I +E T+  +D YAR GLRILVM +R ++   +++W  R++E E  L N E+ L    +++ES++ LLG +GIED LQDGV +TI SL  AGI+VW+LTGDK ETAINIAYSAKLF++   LI L+A S++     I  +L +++++     +    G  + L +K  AL VDG TLTF ++ + K+   FL L+++C SV+C R+TP+QKA +V++VKE L ++TLAIGDGANDVSMIQMADVGVGI G EGMQAVMA+DF + +F+YL+RLLL HG WCY++L+R  LY FYK+  ++ L+FW+Q    FS  +M+D +  +L+N+  T LPP+  GV+DK +  D L++NP LY+NG    +Y+P  FW+ +LDA++QS VI+ +    +  SD+GIWEFG  ITA  L   LVH  IE R WT  H L I +S + ++ +F ++Y  +C     G    Y  IF      + WL+ +++ + A+ PRL + T+R SL P+
Sbjct:  876 YEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTL----GYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLS-LGSFYLFAIVYDSVCMNCF-GVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPD 1468          

Query:  100 PSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVS 1551
            P  +   +    ++  N++RT KY  ++FIP NL EQFHR AN+YF+FI++LN++PEI AFGKEVA IPV+FVL VTA+KD  ED RR  +D+R+N++ C +Y    +++ + KW   R GD V L  NET+PADI+LL ++D  G+C+I+T +LDGE+NLK+REVV    E  + F P     S +E + P  ++Y+F+G +   +    + +    LLLR   L+NT+ + GIVVYAG ETK+MLNN+  R+KRS++E+Q+N DVIWCV++L+ILC+  +IG  +W ++SFT   + Y      +P       M++   FWT ++  Q +IPL LYVT E  K+ QVFHI  +++++D E  K  E RA NI E+LGQIQ++F DKTGTLTEN+M F+R  ++G DY     E +       + S+ G      + +D+   L  ++  +  G       +      +++F +++ ICNT +V 
Sbjct:  237 PPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFV-SRVEADAPTTKLYRFHGALIHPTGE-RVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMW-LSSFTHFPVPY------LPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELE------KIYSKPGAPAPPLIPNDN---LNSDMAQLTQGTYLTPHAQ-----RIQEFLVVLAICNTVIVG 699          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNF---SKDISE-IDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKM--DFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPN 3930
            YE+ESPDE+ALV  A  +   LL R PN + +  P +     Y +L+VLPFDS+RK MSI+V+   +  I+++ KGADS++       S +  E I +E T+  +D YAR GLRILVM +R ++   +++W  R++E E  L N E+ L    +++ES++ LLG +GIED LQDGV +TI SL  AGI+VW+LTGDK ETAINIAYSAKLF++   LI L+A S++     I  +L +++++     +    G  + L +K  AL VDG TLTF ++ + K+   FL L+++C SV+C R+TP+QKA +V++VKE L ++TLAIGDGANDVSMIQMADVGVGI G EGMQAVMA+DF + +F+YL+RLLL HG WCY++L+R  LY FYK+  ++ L+FW+Q    FS  +M+D +  +L+N+  T LPP+  GV+DK +  D L++NP LY+NG    +Y+P  FW+ +LDA++QS VI+ +    +  SD+GIWEFG  ITA  L   LVH  IE R WT  H L I +S + ++ +F ++Y  +C     G    Y  IF      + WL+ +++ + A+ PRL + T+R SL P+
Sbjct:  876 YEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTL----GYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLS-LGSFYLFAIVYDSVCMNCF-GVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPD 1468          

Query:  100 PSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVS 1551
            P  +   +    ++  N++RT KY  ++FIP NL EQFHR AN+YF+FI++LN++PEI AFGKEVA IPV+FVL VTA+KD  ED RR  +D+R+N++ C +Y    +++ + KW   R GD V L  NET+PADI+LL ++D  G+C+I+T +LDGE+NLK+REVV    E  + F P     S +E + P  ++Y+F+G +   +    + +    LLLR   L+NT+ + GIVVYAG ETK+MLNN+  R+KRS++E+Q+N DVIWCV++L+ILC+  +IG  +W ++SFT   + Y      +P       M++   FWT ++  Q +IPL LYVT E  K+ QVFHI  +++++D E  K  E RA NI E+LGQIQ++F DKTGTLTEN+M F+R  ++G DY     E +       + S+ G      + +D+   L  ++  +  G       +      +++F +++ ICNT +V 
Sbjct:  237 PPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFV-SRVEADAPTTKLYRFHGALIHPTGE-RVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMW-LSSFTHFPVPY------LPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELE------KIYSKPGAPAPPLIPNDN---LNSDMAQLTQGTYLTPHAQ-----RIQEFLVVLAICNTVIVG 699          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNF---SKDISE-IDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKM--DFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPN 3930
            YE+ESPDE+ALV  A  +   LL R PN + +  P +     Y +L+VLPFDS+RK MSI+V+   +  I+++ KGADS++       S +  E I +E T+  +D YAR GLRILVM +R ++   +++W  R++E E  L N E+ L    +++ES++ LLG +GIED LQDGV +TI SL  AGI+VW+LTGDK ETAINIAYSAKLF++   LI L+A S++     I  +L +++++     +    G  + L +K  AL VDG TLTF ++ + K+   FL L+++C SV+C R+TP+QKA +V++VKE L ++TLAIGDGANDVSMIQMADVGVGI G EGMQAVMA+DF + +F+YL+RLLL HG WCY++L+R  LY FYK+  ++ L+FW+Q    FS  +M+D +  +L+N+  T LPP+  GV+DK +  D L++NP LY+NG    +Y+P  FW+ +LDA++QS VI+ +    +  SD+GIWEFG  ITA  L   LVH  IE R WT  H L I +S + ++ +F ++Y  +C     G    Y  IF      + WL+ +++ + A+ PRL + T+R SL P+
Sbjct:  876 YEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTL----GYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLS-LGSFYLFAIVYDSVCMNCF-GVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPD 1468          

Query:  100 PSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVS 1551
            P  +   +    ++  N++RT KY  ++FIP NL EQFHR AN+YF+FI++LN++PEI AFGKEVA IPV+FVL VTA+KD  ED RR  +D+R+N++ C +Y    +++ + KW   R GD V L  NET+PADI+LL ++D  G+C+I+T +LDGE+NLK+REVV    E  + F P     S +E + P  ++Y+F+G +   +    + +    LLLR   L+NT+ + GIVVYAG ETK+MLNN+  R+KRS++E+Q+N DVIWCV++L+ILC+  +IG  +W ++SFT   + Y      +P       M++   FWT ++  Q +IPL LYVT E  K+ QVFHI  +++++D E  K  E RA NI E+LGQIQ++F DKTGTLTEN+M F+R  ++G DY     E +       + S+ G      + +D+   L  ++  +  G       +      +++F +++ ICNT +V 
Sbjct:  237 PPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFV-SRVEADAPTTKLYRFHGALIHPTGE-RVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMW-LSSFTHFPVPY------LPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELE------KIYSKPGAPAPPLIPNDN---LNSDMAQLTQGTYLTPHAQ-----RIQEFLVVLAICNTVIVG 699          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNF---SKDISE-IDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKM--DFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPN 3930
            YE+ESPDE+ALV  A  +   LL R PN + +  P +     Y +L+VLPFDS+RK MSI+V+   +  I+++ KGADS++       S +  E I +E T+  +D YAR GLRILVM +R ++   +++W  R++E E  L N E+ L    +++ES++ LLG +GIED LQDGV +TI SL  AGI+VW+LTGDK ETAINIAYSAKLF++   LI L+A S++     I  +L +++++     +    G  + L +K  AL VDG TLTF ++ + K+   FL L+++C SV+C R+TP+QKA +V++VKE L ++TLAIGDGANDVSMIQMADVGVGI G EGMQAVMA+DF + +F+YL+RLLL HG WCY++L+R  LY FYK+  ++ L+FW+Q    FS  +M+D +  +L+N+  T LPP+  GV+DK +  D L++NP LY+NG    +Y+P  FW+ +LDA++QS VI+ +    +  SD+GIWEFG  ITA  L   LVH  IE R WT  H L I +S + ++ +F ++Y  +C     G    Y  IF      + WL+ +++ + A+ PRL + T+R SL P+
Sbjct:  876 YEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTL----GYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLS-LGSFYLFAIVYDSVCMNCF-GVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPD 1468          

Query:  100 PSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVV 1548
            P  +   +    ++  N++RT KY  ++FIP NL EQFHR AN+YF+FI++LN++PEI AFGKEVA IPV+FVL VTA+KD  ED RR  +D+R+N++ C +Y    +++ + KW   R GD V L  NET+PADI+LL ++D  G+C+I+T +LDGE+NLK+REVV    E  + F P     S +E + P  ++Y+F+G +   +    + +    LLLR   L+NT+ + GIVVYAG ETK+MLNN+  R+KRS++E+Q+N DVIWCV++L+ILC+  +IG  +W ++SFT   + Y      +P       M++   FWT ++  Q +IPL LYVT E  K+ QVFHI  +++++D E  K  E RA NI E+LGQIQ++F DKTGTLTEN+M F+R  ++G DY     E +       + S+ G      + +D+   L  ++  +  G       +      +++F +++ ICNT +V
Sbjct:  237 PPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFV-SRVEADAPTTKLYRFHGALIHPTGE-RVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMW-LSSFTHFPVPY------LPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELE------KIYSKPGAPAPPLIPNDN---LNSDMAQLTQGTYLTPHAQ-----RIQEFLVVLAICNTVIV 698          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWE---------FGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYT 3768
            Y + SPDE ALV+ A   GY    R P +V I N    R   Y VL VL F S+RKRMS+IV+ P+ + I +FCKGAD+ ++   +    +  +E T  +++ +A  GLR L +    I  D + EW + + +A   L N E +L    + IE+++ LLG + IED LQDGV +TI SL  AGI +W+LTGDK+ETAINI YS +L S +  +I L+  S + T ++I    G  KS+   +               ++AL +DG+TL +A+  +++ DF  L   C  V+C R +P+QKAE+V++V ++    TLAIGDGANDV+MIQ A+VG+GI G EG+QA  ASD+++ +F+YL+RLLLVHG+W Y ++++  LY FYK+    ++  WF   + +S  ++ +  T  L+N+  T +PP   G+++K   A+T++R P LY+   N K +    FW+ I +A+  S  ++ +    +      IW           G ++    ++T  +  G+ T  WTW   L I+ S +L W  F +IY+
Sbjct:  478 YHAASPDERALVEGAQKFGYIFDTRTPKYVEI-NALGVRK-RYEVLNVLEFTSSRKRMSLIVRTPE-NKIKLFCKGADTVIYERLAPQ-GQAFREQTLRHLEEFASDGLRTLCLAVADIRPDVYQEWSQTFDKASVALQNRESKLEDAANLIENNLRLLGATAIEDRLQDGVPETIASLLDAGIYIWVLTGDKQETAINIGYSCRLISHSMDIIILNEESLDATREVIHRHYGEFKSSSAKD--------------ANVALVIDGTTLKYALSCDLRNDFQDLCILCRVVICCRVSPMQKAEVVEMVTQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAACASDYSIAQFRYLQRLLLVHGAWNYARISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTIGLYNVLFTAMPPFAMGLFEKFCTAETMIRYPMLYKTSQNAKLFNVKVFWIWIFNALLHSVFLFWLPLAAYTKEV--IWSDGKTSDYLLMGNLVYTYVIVTVCLKAGLITNSWTWLTHLAIWGSIVL-WFGFLLIYS 1004          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV-----MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQ 1350
            KY NN + T KY+ I+F+P  LFEQF R++N +F+ I IL  +PE+   G+    +P++F+LSV+AIK+ +ED +R +AD  +NH    I       +   +WS    GD +K+  N   PAD++LL S++   +C IET+NLDGE+NLK R+ +     ++E  +  + E      IE E PN+ +Y+FNG +  ++      L  + +L RG  LRNT  V GIVVY+G+ETK M N+     KRS +++  N  ++   ++LI LC+   + N+ WT      D+  Y    D      +  ++   L   T  I Y  LIP+ L VT E V+  Q   I  D+EMY  E+      R  N+ E+LG ++Y+F DKTGTLT+N MEFK+  I G  Y  +    + Q
Sbjct:   45 KYGNNRITTAKYSFISFLPAFLFEQFRRYSNCFFLLIAILQQIPEVSPTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADNEINHRS--IERLDSGSWCTVRWSELTVGDIIKVGINTFFPADLILLSSSEPQAMCFIETANLDGETNLKIRQALPATAELLETKDLQRLE----GRIECELPNRHLYEFNG-VLRETGKPPAALGNDQVLQRGAILRNTAWVFGIVVYSGQETKLMKNSTSAPLKRSTVDKLTNTQILMLFMILISLCIISGLCNLFWTREHSETDW--YLGLTD-----FKTKSLGYNLL--TFFILYNNLIPISLQVTLELVRFLQAIFINYDIEMYHEESNTPAMARTSNLNEELGMVKYIFSDKTGTLTQNVMEFKKCSIAGYVYTAERTPEESQ 438          

Query: 1825 LPDFDDIHIRITDTNQKDYVQTPNKSRK----------VKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVH------IELSYIADTYSDINTEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQEN-------TKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNY-------PNEIME-------------IRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRW----LFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGL--------IREEKLGKGSNLYFDYEPE 4005
            L D  D  I +T  N    V +PN+ R+          VK++ DF         T   ++ + + L TN+ S H      +      +T + +N E        D  K    ++C +        +E+ESPDE ALV  A  +   L+ R P+ VT+  P   + +++ +L  L FDS RKRMS++VK P T+ I ++ KGADS +         +   +        T++Y++ YA  GLR L + ++V+SK+ ++ W +R+ EAE  +   E+ L      +E+++ LLG +GIED LQDGV +TI SLR+AG+ +W+LTGDK+ETAINIAY+ KL    + +I L+A S+E    L++  L  I++ +       P    +                G + P +   L L +DG TL +A++  ++  FL +A  C SV+C R+TP+QK+ +V+LV+  L++ TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F+YL++LLLVHG WCY++LA   LY FYK+ +++ L+FW+QF   FS S M+D    + FN+  +  P +I G  DKD+ A+TL   P+LY NG N + YKP+ FW+N++DA +QS + + I Y  ++ SD+ ++ +G  IT  AL T L+HLGIET+ WTW + + I  S  L + V  + Y   C      S+      +  MQR     LF+LLCVVTP+AA+ PR      + +L+PN ++ G         +R   L + S +  DY P+
Sbjct:  558 LCDVFDFFIALTICNTV-VVSSPNQPRQKVRRFELKSPVKTIEDFIKRFTPSRLTSGSNSSSSSSLATNRSSSHKLGCSMLSSPSAENTLTKLNEEKRPVPPNFDKSKALAQDECELR-------FEAESPDEAALVYAARAYKCALVGRLPDQVTVELPHLGK-LSFELLHTLGFDSTRKRMSVVVKHPLTEQITVYTKGADSVIMDLIRPATDDCKGKRQRKILYKTQNYLNLYAADGLRTLCIAKKVLSKEEYASWLQRHLEAETAIQRREELLFESALRLETNLQLLGATGIEDRLQDGVPETIASLRKAGLQIWVLTGDKQETAINIAYACKLLDPEEEIITLNADSQEACARLLENSLHYIQAKFLCDPRAGPQAAGDYAGIHFSSPVCSPTSSGHSGPFLVHRLGLVIDGRTLAYALDKSLEDKFLAVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFRYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMVDQWYLIFFNLMFSAFPQLITGTLDKDVSAETLQELPQLYMNGQNSEEYKPYMFWMNMIDAFYQSLICFFIPYFAYIDSDVDLFTWGTPITTLALFTILLHLGIETKTWTWMNWVSIGFSMALFFTV-ALCYNASCPTCFSPSN-----TYWTMQRLLGDPLFYLLCVVTPVAALLPRYCYRACQGTLFPNPVHMGRQLDKLPVEMRRLVLSQ-SQMKLDYRPK 1323          

Query:   94 IYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA-------------VKDDETDG----------------QSDKVTMRSEFGDTDDKKMNDDHGKK-------------LLKNLI--PMLHGDIEIKEEEMSRMK--------------NVKDFFLLMGICNTTVVS 1551
            +Y  T    N  ++ YANN+++T KY  ++F+P NLFEQFHRFAN+YFVFI +LNF+P + AF  E+A  PVVF+LSVTAIKD  EDYRR ++D+ +NH  CL+Y  ++K++VE+ W   R GDF++L  NE +PAD++LL ++D   +CHIET+ LDGE+NLKQR+VV   ++ +  F P +  NS IE E PN ++ +F G I  +S      L K+NLLLRGCT+RNTEE +GIV+YAG ETKAMLNNN  R+KRSKLERQ+N DV WCV++L+++CL  +IG+ +W      +  +     P+       +P + A   F T +I +Q LIP+ L+V+ E VK+ QV+ I +DLE+YD E +  L+ RA NI EDLGQ+QY+F DKTGTLTEN+M F+R  + G +Y+             V+ +E D                 QS KV +RS+   +  +  +    K+             + K++   P L   +     +M  M+              +V DFF+ + ICNT VVS
Sbjct:   38 LYDHTKGGDNPNRH-YANNKIKTTKYTLLSFLPKNLFEQFHRFANVYFVFIALLNFVPVVNAFQPELALAPVVFILSVTAIKDLWEDYRRHRSDKEINHMDCLVYCRSEKRYVEKYWKELRVGDFIRLRCNEILPADVLLLSTSDPDRLCHIETATLDGETNLKQRQVVRSFIDLDCEFDP-LKYNSVIECEKPNNDLNRFRGYIIHRSGRRD-GLYKDNLLLRGCTIRNTEEAVGIVIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFSAIGHGLWMFQYGDKRPVFDVLGPEGTEL---SPVVSAIYLFLTMIIVFQVLIPISLFVSIEIVKICQVYFIHQDLELYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYSHDANARRIAMYQEVESEEEDCTSHGGTLPRRDSVASHQSGKVVLRSQSTKSHRRTGSRAEAKRASILSKHTAFSSPMEKDITPDPQLMDKVNECSSQMEFMRFHSQSLNQIPPDLCDVFDFFIALTICNTVVVS 577          

Query: 1825 LPDFDDIHIRITDTNQKDYVQTPNKSRK----------VKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVH------IELSYIADTYSDINTEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQEN-------TKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNY-------PNEIME-------------IRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRW----LFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGL--------IREEKLGKGSNLYFDYEPE 4005
            L D  D  I +T  N    V +PN+ R+          VK++ DF         T   ++ + + L TN+ S H      +      +T + +N E        D  K    ++C +        +E+ESPDE ALV  A  +   L+ R P+ VT+  P   + +++ +L  L FDS RKRMS++VK P T+ I ++ KGADS +         +   +        T++Y++ YA  GLR L + ++V+SK+ ++ W +R+ EAE  +   E+ L      +E+++ LLG +GIED LQDGV +TI SLR+AG+ +W+LTGDK+ETAINIAY+ KL    + +I L+A S+E    L++  L  I++ +       P    +                G + P +   L L +DG TL +A++  ++  FL +A  C SV+C R+TP+QK+ +V+LV+  L++ TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F+YL++LLLVHG WCY++LA   LY FYK+ +++ L+FW+QF   FS S M+D    + FN+  +  P +I G  DKD+ A+TL   P+LY NG N + YKP+ FW+N++DA +QS + + I Y  ++ SD+ ++ +G  IT  AL T L+HLGIET+ WTW + + I  S  L + V  + Y   C      S+      +  MQR     LF+LLCVVTP+AA+ PR      + +L+PN ++ G         +R   L + S +  DY P+
Sbjct:  558 LCDVFDFFIALTICNTV-VVSSPNQPRQKVRRFELKSPVKTIEDFIKRFTPSRLTSGSNSSSSSSLATNRSSSHKLGCSMLSSPSAENTLTKLNEEKRPVPPNFDKSKALAQDECELR-------FEAESPDEAALVYAARAYKCALVGRLPDQVTVELPHLGK-LSFELLHTLGFDSTRKRMSVVVKHPLTEQITVYTKGADSVIMDLIRPATDDCKGKRQRKILYKTQNYLNLYAADGLRTLCIAKKVLSKEEYASWLQRHLEAETAIQRREELLFESALRLETNLQLLGATGIEDRLQDGVPETIASLRKAGLQIWVLTGDKQETAINIAYACKLLDPEEEIITLNADSQEACARLLENSLHYIQAKFLCDPRAGPQAAGDYAGIHFSSPVCSPTSSGHSGPFLVHRLGLVIDGRTLAYALDKSLEDKFLAVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFRYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMVDQWYLIFFNLMFSAFPQLITGTLDKDVSAETLQELPQLYMNGQNSEEYKPYMFWMNMIDAFYQSLICFFIPYFAYIDSDVDLFTWGTPITTLALFTILLHLGIETKTWTWMNWVSIGFSMALFFTV-ALCYNASCPTCFSPSN-----TYWTMQRLLGDPLFYLLCVVTPVAALLPRYCYRACQGTLFPNPVHMGRQLDKLPVEMRRLVLSQ-SQMKLDYRPK 1323          

Query:   94 IYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA-------------VKDDETDG----------------QSDKVTMRSEFGDTDDKKMNDDHGKK-------------LLKNLI--PMLHGDIEIKEEEMSRMK--------------NVKDFFLLMGICNTTVVS 1551
            +Y  T    N  ++ YANN+++T KY  ++F+P NLFEQFHRFAN+YFVFI +LNF+P + AF  E+A  PVVF+LSVTAIKD  EDYRR ++D+ +NH  CL+Y  ++K++VE+ W   R GDF++L  NE +PAD++LL ++D   +CHIET+ LDGE+NLKQR+VV   ++ +  F P +  NS IE E PN ++ +F G I  +S      L K+NLLLRGCT+RNTEE +GIV+YAG ETKAMLNNN  R+KRSKLERQ+N DV WCV++L+++CL  +IG+ +W      +  +     P+       +P + A   F T +I +Q LIP+ L+V+ E VK+ QV+ I +DLE+YD E +  L+ RA NI EDLGQ+QY+F DKTGTLTEN+M F+R  + G +Y+             V+ +E D                 QS KV +RS+   +  +  +    K+             + K++   P L   +     +M  M+              +V DFF+ + ICNT VVS
Sbjct:   38 LYDHTKGGDNPNRH-YANNKIKTTKYTLLSFLPKNLFEQFHRFANVYFVFIALLNFVPVVNAFQPELALAPVVFILSVTAIKDLWEDYRRHRSDKEINHMDCLVYCRSEKRYVEKYWKELRVGDFIRLRCNEILPADVLLLSTSDPDRLCHIETATLDGETNLKQRQVVRSFIDLDCEFDP-LKYNSVIECEKPNNDLNRFRGYIIHRSGRRD-GLYKDNLLLRGCTIRNTEEAVGIVIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFSAIGHGLWMFQYGDKRPVFDVLGPEGTEL---SPVVSAIYLFLTMIIVFQVLIPISLFVSIEIVKICQVYFIHQDLELYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYSHDANARRIAMYQEVESEEEDCTSHGGTLPRRDSVASHQSGKVVLRSQSTKSHRRTGSRAEAKRASILSKHTAFSSPMEKDITPDPQLMDKVNECSSQMEFMRFHSQSLNQIPPDLCDVFDFFIALTICNTVVVS 577          

Query: 1825 LPDFDDIHIRITDTNQKDYVQTPNKSRK----------VKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVH------IELSYIADTYSDINTEGDRNNSGIDSFKN---DQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQEN-------TKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNY-------PNEIME-------------IRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRW----LFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            L D  D  I +T  N    V +PN+ R+          VK++ DF         T   ++ + + L TN+ S H      +      +T + +N E  + +    +F     + D    ++  +    +E+ESPDE ALV  A  +   L+ R P+ VT+  P   + +++ +L  L FDS RKRMS++VK P T+ I ++ KGADS +         +   +        T++Y++ YA  GLR L + ++V+SK+ ++ W +R+ EAE  +   E+ L      +E+++ LLG +GIED LQDGV +TI SLR+AG+ +W+LTGDK+ETAINIAY+ KL    + +I L+A S+E    L++  L  I++ +       P    +                G + P +   L L +DG TL +A++  ++  FL +A  C SV+C R+TP+QK+ +V+LV+  L++ TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F+YL++LLLVHG WCY++LA   LY FYK+ +++ L+FW+QF   FS S M+D    + FN+  +  P +I G  DKD+ A+TL   P+LY NG N + YKP+ FW+N++DA +QS + + I Y  ++ SD+ ++ +G  IT  AL T L+HLGIET+ WTW + + I  S  L + V  + Y   C      S+      +  MQR     LF+LLCVVTP+AA+ PR      + +L+PN ++ G
Sbjct:  558 LCDVFDFFIALTICNTV-VVSSPNQPRQKVRRFELKSPVKTIEDFIKRFTPSRLTSGSNSSSSSSLATNRSSSHKLGCSMLSSPSAENTLTKLNEEKRQEHDLQHAFSPVPPNFDKSKALAQDECELRFEAESPDEAALVYAARAYKCALVGRLPDQVTVELPHLGK-LSFELLHTLGFDSTRKRMSVVVKHPLTEQITVYTKGADSVIMDLIRPATDDCKGKRQRKILYKTQNYLNLYAADGLRTLCIAKKVLSKEEYASWLQRHLEAETAIQRREELLFESALRLETNLQLLGATGIEDRLQDGVPETIASLRKAGLQIWVLTGDKQETAINIAYACKLLDPEEEIITLNADSQEACARLLENSLHYIQAKFLCDPRAGPQAAGDYAGIHFSSPVCSPTSSGHSGPFLVHRLGLVIDGRTLAYALDKSLEDKFLAVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFRYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMVDQWYLIFFNLMFSAFPQLITGTLDKDVSAETLQELPQLYMNGQNSEEYKPYMFWMNMIDAFYQSLICFFIPYFAYIDSDVDLFTWGTPITTLALFTILLHLGIETKTWTWMNWVSIGFSMALFFTV-ALCYNASCPTCFSPSN-----TYWTMQRLLGDPLFYLLCVVTPVAALLPRYCYRACQGTLFPNPVHMG 1306          

Query:   94 IYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPT--------VIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA-------------VKDDETD----------------GQSDKVTMRSEFGDTDDKKMNDDHGKK-------------LLKNLI--PMLHGDIEIKEEEMSRMK--------------NVKDFFLLMGICNTTVVS 1551
            +Y  T    N  ++ YANN+++T KY  ++F+P NLFEQFHRFAN+YFVFI +LNF+P + AF  E+A  PVVF+LSVTAIKD  EDYRR ++D+ +NH  CL+Y  ++K++VE+ W   R GDF++L  NE +PAD++LL ++D   +CHIET+ LDGE+NLKQR+VV   ++ +  F P +  NS IE E PN ++ +F G I  +S      L K+NLLLRGCT+RNTEE +GIV+YAG ETKAMLNNN  R+KRSKLERQ+N DV WCV++L+++CL  +IG+ +W            +++ D  P            +P + A   F T +I +Q LIP+ L+V+ E VK+ QV+ I +DLE+YD E +  L+ RA NI EDLGQ+QY+F DKTGTLTEN+M F+R  + G +Y+             V+ +E D                 QS KV +RS+   +  +  +    K+             + K++   P L   +     +M  M+              +V DFF+ + ICNT VVS
Sbjct:   38 LYDHTKGGDNPNRH-YANNKIKTTKYTLLSFLPKNLFEQFHRFANVYFVFIALLNFVPVVNAFQPELALAPVVFILSVTAIKDLWEDYRRHRSDKEINHMDCLVYCRSEKRYVEKYWKELRVGDFIRLRCNEILPADVLLLSTSDPDRLCHIETATLDGETNLKQRQVVRSFIDLDCEFDP-LKYNSVIECEKPNNDLNRFRGYIIHRSGRRD-GLYKDNLLLRGCTIRNTEEAVGIVIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFSAIGHGLWM-----------FQYGDKRPVFDVLGPEGTELSPVVSAIYLFLTMIIVFQVLIPISLFVSIEIVKICQVYFIHQDLELYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYSHDANARRIAMYQEVESEEEDCTSHGGTLPRRDSVASHQSGKVVLRSQSTKSHRRTGSRAEAKRASILSKHTAFSSPMEKDITPDPQLMDKVNECSSQMEFMRFHSQSLNQIPPDLCDVFDFFIALTICNTVVVS 577          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAM---FGN-FSKDIS--EIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPN-----EIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNL 3933
            YE+ SPDE AL+  A  +G+ +++R P +VT+  P +E  + + VL VL FDS R+RMSIIV+ P T+ IIM+ KGADSA+    GN FS + +   I     KD +D YAR GLR L   ++VIS+  F  W    +EA   +   E+ L+   ++IE+++ LLG +GIED LQ+ V +TI++LRRAG+ VW+LTGDK ETA+NIAYS KL      +   + + K      +++ L  ++  +       +        T PL+   + L +DG TL  A+ +++   F+ L + C +V+C R TP+QK+ +V+++++ LR+ TLA+GDGANDV+MIQ ADVG+G+ G EGMQAVMASDFA+T+FK+L+RLLLVHG WCY++LA   +Y FYK+  Y+ L+FW+QF   FS + MID    + FN+  T  PPI++G+ DK++   TL+  PELYR G + + Y+   FW+ ILDA +QS V + I Y T+  SDIGI+ FG  +   +L T ++HL IE + WT  H + I +  +L + + T+ Y+ IC  + C    DPY  + + M   +F+L+CV+T + A+ PR T+  ++ +L P+L
Sbjct:  652 YEAHSPDEAALIHAAKAYGFTMVERTPRYVTVKLP-NETLLKFEVLDVLTFDSTRRRMSIIVRHPHTNEIIMYTKGADSAVMEKLGNVFSVESAAKRIAVRTQKD-LDMYARDGLRTLCFAKKVISEQEFKAWFTSRQEALSAIDEKEERLMETANDIENNLTLLGATGIEDRLQENVPETIQALRRAGMQVWVLTGDKPETAVNIAYSCKLLDHEDLVFTFTTNKKSVCKMRLEDTLSEVRRTWGGLGLDPQFRGYNSTFTGPLMEPSIGLVIDGPTLNMALSEDLVEQFVELCKHCRAVLCCRVTPLQKSSVVKVIRQKLRVMTLAVGDGANDVNMIQAADVGIGVSGQEGMQAVMASDFAITRFKHLQRLLLVHGHWCYSRLANMVIYFFYKNVAYVNLLFWYQFFCGFSGTAMIDYWLMIFFNLFFTSAPPIMFGIMDKEVSDSTLLSLPELYRRGQHSEGYRRSTFWIAILDAFYQSLVCFFIPYWTYNDSDIGIFSFGTPMNTVSLFTIILHLAIEIKSWTVVHWV-IMVGSVLVYFILTLAYSAIC--ISCNPPSDPYWIMHKQMADPMFYLVCVLTTVVALLPRYTLRVLKGTLAPSL 1252          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFF---KSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDD 1335
            +Y  N ++T KY   +F+P+NLFEQFHR ANIYFV + ILNF+P + AF  EVA IP+  +L++TA+KD  ED+RR++ DQ++N+  C I+      FVE++W   R GDFVK+ +NE IPADI+LLH++D +G+CH+ET+NLDGE+NLKQR+VV         F+P+   ++ +  ENPN  +  F G I     +    GI    ++LLLRGCT+RNT++  GIVVYAG ETK+MLNNN  R+KRSK+ER++N DV++CVLLL  +CL  ++G+ IW  T  T   +  Y  PDS    I + A+  F  F+T +I  Q +IP+ LYV+ E VKM Q+F I +D E+YD E +  ++ RA NI EDLGQIQYVF DKTGTLTEN+M FKR  I G +Y  +++
Sbjct:   45 QYEGNAIKTNKYRLWSFLPMNLFEQFHRLANIYFVGLAILNFIPVVNAFQPEVALIPICIILALTAVKDGWEDFRRYQTDQQLNNMPCFIFRRRLMCFVERRWKDVRVGDFVKVLSNEIIPADILLLHTSDPNGVCHMETANLDGETNLKQRKVVPGFSTLGEPFQPQTFDSTVV-CENPNNNLNLFKGFIERPDKRRSGFGI----DSLLLRGCTVRNTDDAAGIVVYAGHETKSMLNNNGPRYKRSKIERKMNTDVLFCVLLLFFMCLIGALGHAIWLETFST---MPSYIVPDSNGNYISS-ALAGFYMFFTMIILLQVMIPVSLYVSIELVKMGQIFFITQDAELYDQELDSRVQCRALNITEDLGQIQYVFSDKTGTLTENKMVFKRCTIMGTEYCHEEN 440          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAM---FGN-FSKDIS--EIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPN-----EIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNL 3933
            YE+ SPDE AL+  A  +G+ +++R P +VT+  P +E  + + VL VL FDS R+RMSIIV+ P T+ IIM+ KGADSA+    GN FS + +   I     KD +D YAR GLR L   ++VIS+  F  W    +EA   +   E+ L+   ++IE+++ LLG +GIED LQ+ V +TI++LRRAG+ VW+LTGDK ETA+NIAYS KL      +   + + K      +++ L  ++  +       +        T PL+   + L +DG TL  A+ +++   F+ L + C +V+C R TP+QK+ +V+++++ LR+ TLA+GDGANDV+MIQ ADVG+G+ G EGMQAVMASDFA+T+FK+L+RLLLVHG WCY++LA   +Y FYK+  Y+ L+FW+QF   FS + MID    + FN+  T  PPI++G+ DK++   TL+  PELYR G + + Y+   FW+ ILDA +QS V + I Y T+  SDIGI+ FG  +   +L T ++HL IE + WT  H + I +  +L + + T+ Y+ IC  + C    DPY  + + M   +F+L+CV+T + A+ PR T+  ++ +L P+L
Sbjct:  652 YEAHSPDEAALIHAAKAYGFTMVERTPRYVTVKLP-NETLLKFEVLDVLTFDSTRRRMSIIVRHPHTNEIIMYTKGADSAVMEKLGNVFSVESAAKRIAVRTQKD-LDMYARDGLRTLCFAKKVISEQEFKAWFTSRQEALSAIDEKEERLMETANDIENNLTLLGATGIEDRLQENVPETIQALRRAGMQVWVLTGDKPETAVNIAYSCKLLDHEDLVFTFTTNKKSVCKMRLEDTLSEVRRTWGGLGLDPQFRGYNSTFTGPLMEPSIGLVIDGPTLNMALSEDLVEQFVELCKHCRAVLCCRVTPLQKSSVVKVIRQKLRVMTLAVGDGANDVNMIQAADVGIGVSGQEGMQAVMASDFAITRFKHLQRLLLVHGHWCYSRLANMVIYFFYKNVAYVNLLFWYQFFCGFSGTAMIDYWLMIFFNLFFTSAPPIMFGIMDKEVSDSTLLSLPELYRRGQHSEGYRRSTFWIAILDAFYQSLVCFFIPYWTYNDSDIGIFSFGTPMNTVSLFTIILHLAIEIKSWTVVHWV-IMVGSVLVYFILTLAYSAIC--ISCNPPSDPYWIMHKQMADPMFYLVCVLTTVVALLPRYTLRVLKGTLAPSL 1252          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFF---KSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDD 1335
            +Y  N ++T KY   +F+P+NLFEQFHR ANIYFV + ILNF+P + AF  EVA IP+  +L++TA+KD  ED+RR++ DQ++N+  C I+      FVE++W   R GDFVK+ +NE IPADI+LLH++D +G+CH+ET+NLDGE+NLKQR+VV         F+P+   ++ +  ENPN  +  F G I     +    GI    ++LLLRGCT+RNT++  GIVVYAG ETK+MLNNN  R+KRSK+ER++N DV++CVLLL  +CL  ++G+ IW  T  T   +  Y  PDS    I + A+  F  F+T +I  Q +IP+ LYV+ E VKM Q+F I +D E+YD E +  ++ RA NI EDLGQIQYVF DKTGTLTEN+M FKR  I G +Y  +++
Sbjct:   45 QYEGNAIKTNKYRLWSFLPMNLFEQFHRLANIYFVGLAILNFIPVVNAFQPEVALIPICIILALTAVKDGWEDFRRYQTDQQLNNMPCFIFRRRLMCFVERRWKDVRVGDFVKVLSNEIIPADILLLHTSDPNGVCHMETANLDGETNLKQRKVVPGFSTLGEPFQPQTFDSTVV-CENPNNNLNLFKGFIERPDKRRSGFGI----DSLLLRGCTVRNTDDAAGIVVYAGHETKSMLNNNGPRYKRSKIERKMNTDVLFCVLLLFFMCLIGALGHAIWLETFST---MPSYIVPDSNGNYISS-ALAGFYMFFTMIILLQVMIPVSLYVSIELVKMGQIFFITQDAELYDQELDSRVQCRALNITEDLGQIQYVFSDKTGTLTENKMVFKRCTIMGTEYCHEEN 440          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF--------GNFS--KDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIME-IRQGKTRPL------IRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSD-DPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLGK 3972
            YE+ESPDE ALV  A  + + L+ R P+ VT+  P+    +T+ +L  L FDS RKRMS++V+ P T  II++ KGADS +          N S  K + ++ Q  T+ ++D YAR GLR L + ++V+S+D F  W    +EAE  + N E+ L+     +E+++ LLG +GIED LQ+GV DTI SLR AGI +W+LTGDK+ETA+NIAYS +L  +   +  ++  SKE    ++   L ++K  +P +    + +    P+      +R  + L +DG TL    +  ++  FL L+  C SV+C R TP+QK+ +V+LV++ L++ TL+IGDGANDVSMIQ AD+G+GI G EGMQAVM+SDFA+++FK+LK+LLLVHG WCY +LA   +Y FYK+  Y+ L+FW+Q    FS + MID    + FN+  T +PP+++G+ DKD+ A+TLM  P LY++G  CKSYK   FW+ I+DA +QS V + I Y T+  +DI +  FG  I   AL T L+HL IE + WT  H + I +S I+ + V ++ Y  IC  V+C    +PY  +   M   LF+++C++TP+ A+ PR  I  +R +   N L     + +KLGK
Sbjct:  707 YEAESPDEAALVHAARAYSFTLMSRTPDQVTVRLPQGTL-LTFDLLYTLGFDSVRKRMSVVVRHPITREIIVYTKGADSVIMDLLDDPSKANISDEKKLRKM-QARTQRHLDWYARDGLRTLCIAKKVLSEDEFERWSNFREEAEAAIENREELLMETAQHLETNLSLLGATGIEDRLQEGVPDTIASLREAGINIWVLTGDKQETAVNIAYSCQLLDQYDTVFTINTESKETCESILDCTLEDVKKFFPEKKKRGLFKRSKAPVSHELEAVRPQVGLVIDGRTLNVIFQGGLETKFLELSRHCRSVLCCRATPLQKSMVVKLVRDKLKVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAISRFKHLKKLLLVHGHWCYTRLANMVIYFFYKNVAYVNLLFWYQLFCGFSGTTMIDYWQMIFFNLFFTSVPPLVFGILDKDISAETLMSLPHLYKSGQQCKSYKMSTFWIAIVDAFYQSLVCFFIPYFTYQGTDIDVLSFGTPINTIALFTILMHLAIEIKTWTILHWVTIVVS-IICYFVVSLAYNAIC--VLCNEPANPYWIMEMQMSDPLFYIVCIITPVIALLPRYFIRALRGTCVANPLILAQ-KLDKLGK 1325          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFF-KSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKM 1404
            Y  N++RT KY  ++F+P NLFEQF+R ANIYFVF+  LN++P+I  F KE+  +P+  VL V AIKDAVEDY+R++ D+R+N +K  +Y+     FVE+ W     GDFVKL  NE IPADI+LL  +D +GICHIET+NLDGE+NLKQR+VV    +    F PE   N+ +  E PN  + KF G +     Q  G      +LLLRGCT+RNTEEV+GIVVYAG ETKAMLNN+  R+KRSK+ERQ+N +V +CV +L I+CL  ++G  IWT + F       +  P++  + + +PA+  F  F T +I  Q LIP+ LYV+ E VK+ Q++ I  DL++YD E +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  I G +++ +++     + ++ M +E  ++DD+ M
Sbjct:   62 YKGNKIRTTKYTLLSFLPKNLFEQFYRSANIYFVFLAALNWVPQIGVFHKEITMVPLAIVLGVIAIKDAVEDYKRYRIDRRINFTKTSVYNKNSNDFVEKCWKDVCVGDFVKLLCNEIIPADILLLFCSDQNGICHIETANLDGETNLKQRQVVKGFCKQGMAFDPESFRNTIV-CEKPNNNLNKFKGYMQLDNGQRTGFG--NESLLLRGCTVRNTEEVVGIVVYAGHETKAMLNNSGPRYKRSKIERQMNINVFFCVGILFIMCLIGALGYGIWT-SKFV--IPPLFDVPEADGSYL-SPALAGFYMFLTMIILLQILIPISLYVSIELVKLGQIYLIHSDLDLYDEEIDLSVQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGYEFSHQEN-----AKRLEMYNE-EESDDEDM 473          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF--------GNFS--KDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIME-IRQGKTRPL------IRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSD-DPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLGK 3972
            YE+ESPDE ALV  A  + + L+ R P+ VT+  P+    +T+ +L  L FDS RKRMS++V+ P T  II++ KGADS +          N S  K + ++ Q  T+ ++D YAR GLR L + ++V+S+D F  W    +EAE  + N E+ L+     +E+++ LLG +GIED LQ+GV DTI SLR AGI +W+LTGDK+ETA+NIAYS +L  +   +  ++  SKE    ++   L ++K  +P +    + +    P+      +R  + L +DG TL    +  ++  FL L+  C SV+C R TP+QK+ +V+LV++ L++ TL+IGDGANDVSMIQ AD+G+GI G EGMQAVM+SDFA+++FK+LK+LLLVHG WCY +LA   +Y FYK+  Y+ L+FW+Q    FS + MID    + FN+  T +PP+++G+ DKD+ A+TLM  P LY++G  CKSYK   FW+ I+DA +QS V + I Y T+  +DI +  FG  I   AL T L+HL IE + WT  H + I +S I+ + V ++ Y  IC  V+C    +PY  +   M   LF+++C++TP+ A+ PR  I  +R +   N L     + +KLGK
Sbjct:  691 YEAESPDEAALVHAARAYSFTLMSRTPDQVTVRLPQGTL-LTFDLLYTLGFDSVRKRMSVVVRHPITREIIVYTKGADSVIMDLLDDPSKANISDEKKLRKM-QARTQRHLDWYARDGLRTLCIAKKVLSEDEFERWSNFREEAEAAIENREELLMETAQHLETNLSLLGATGIEDRLQEGVPDTIASLREAGINIWVLTGDKQETAVNIAYSCQLLDQYDTVFTINTESKETCESILDCTLEDVKKFFPEKKKRGLFKRSKAPVSHELEAVRPQVGLVIDGRTLNVIFQGGLETKFLELSRHCRSVLCCRATPLQKSMVVKLVRDKLKVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAISRFKHLKKLLLVHGHWCYTRLANMVIYFFYKNVAYVNLLFWYQLFCGFSGTTMIDYWQMIFFNLFFTSVPPLVFGILDKDISAETLMSLPHLYKSGQQCKSYKMSTFWIAIVDAFYQSLVCFFIPYFTYQGTDIDVLSFGTPINTIALFTILMHLAIEIKTWTILHWVTIVVS-IICYFVVSLAYNAIC--VLCNEPANPYWIMEMQMSDPLFYIVCIITPVIALLPRYFIRALRGTCVANPLILAQ-KLDKLGK 1309          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFF-KSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKM 1404
            +Y  N+++T KY   TFIP NLFEQFHRFAN+YFV +  LNF+P + AF   +A IP+  +L++TAIKD  ED+RRFK+D+ +N+  CL+Y+     FVE+ W     GDFVKL  NE IPADI+LL  +D +GICHIET+NLDGE+NLKQR+VV    +    F PE   N+ +  E PN  + KF G +     Q  G      +LLLRGCT+RNTEEV+GIVVYAG ETKAMLNN+  R+KRSK+ERQ+N +V +CV +L I+CL  ++G  IWT + F       +  P++  + + +PA+  F  F T +I  Q LIP+ LYV+ E VK+ Q++ I  DL++YD E +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  I G +++ +++     + ++ M +E  ++DD+ M
Sbjct:   45 QYQTNKIKTTKYTFFTFIPKNLFEQFHRFANVYFVAVAALNFVPVVNAFQPAIAIIPICIILAITAIKDIWEDFRRFKSDKEINYMSCLVYNRNSNDFVEKCWKDVCVGDFVKLLCNEIIPADILLLFCSDQNGICHIETANLDGETNLKQRQVVKGFCKQGMAFDPESFRNTIV-CEKPNNNLNKFKGYMQLDNGQRTGFG--NESLLLRGCTVRNTEEVVGIVVYAGHETKAMLNNSGPRYKRSKIERQMNINVFFCVGILFIMCLIGALGYGIWT-SKFV--IPPLFDVPEADGSYL-SPALAGFYMFLTMIILLQILIPISLYVSIELVKLGQIYLIHSDLDLYDEEIDLSVQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGYEFSHQEN-----AKRLEMYNE-EESDDEDM 457          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEID---------QENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKT------------RPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            +E+ESPDE ALV  +  +   L+ R  + VT+  P   R + + +L  L FDS RKRMS++V+ P TD I+++ KGADS +  +  +  S+ D         Q  T+ Y++ YA  GLR L + +RV+SK+ ++ W K + +AE  L N E+ L      +E+++ LLG +GIED LQ+GV +TI  LR+AGI +W+LTGDK+ETA+NI YS KL      LI L+A S E+   L+++ L  I+S + + + E   G T              L +  L L +DG TL FA++      FL LA +C SV+C R+TP+QK+ +V+LV++ LR  TLA+GDG NDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F++L++LLLVHG WCY++LA   LY FYK+ +++ L+FW+QF   FS S MID    + FN+  + +P +I G+ DKDL A+ L  NPELY++G N + YKP  FW+N++DA +QS V + I Y +F  SDI ++ +G  I  CAL+T ++HLG+ET+ WTW +   I  S IL +    ++Y   C      S +PY  + + M   LF+L+C+++P+ A+ PR    +++ +L+P  +  G
Sbjct:  686 FEAESPDEAALVYASRAYNCALVGRLSDQVTVELPHLGR-LNFELLHTLGFDSVRKRMSVVVRHPLTDEIVVYAKGADSVIL-DLIQPCSKDDRLGKHQRKIQAKTQKYLNCYAVDGLRTLCIAKRVLSKEEYACWLKFHLQAESSLDNREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETITRLRKAGIQIWVLTGDKQETAVNIGYSCKLLDHEDDLITLNAESLEECSTLLEQCLHYIQSKFSSGLQEKVVGGTGIDSVQHNTLWPPNLKQSSLGLVIDGKTLAFALDITQSDKFLLLARKCRSVLCCRSTPLQKSLVVKLVRDKLRAMTLAVGDGTNDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRHLEKLLLVHGRWCYSRLANMVLYFFYKNAMFVALLFWYQFYCGFSGSAMIDQWYLIFFNLLFSSIPQLITGILDKDLPAELLTANPELYKSGPNMEEYKPHMFWLNMIDAFYQSLVCFFIPYFSFFDSDIDLFTWGTPIVTCALLTIMMHLGMETKTWTWINVSSIVFS-ILLFFTVALVYNSSCPTCNPPS-NPYWTMQKLMANPLFYLICILSPVTALLPRFLYKSVQGTLFPTQIQLG 1300          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTV--------IRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDK 1398
            YA N ++T KY A++F+P NLFEQFHR AN+YFVF+ +LNF+P + AF  E+A  PV+F+L+VTAIKD  EDYRR+++D+ +NH  CL++  ++K++ E+ W   + GDFV+L  NE IPADI+LL S+D  G+CHIET+NLDGE+NLKQR+V+   +E  + F P M   S IE E PN ++ +F G I    +  G  L K NLLLRGCT+RNTE V GIV+YAG ETKA+LNNN  R+KRSKLERQ+NKDV WCVL+L+I+CL  ++G+ +W            +++ +  P             P + A   F+T +I  Q LIP+ LYV+ E VK+ QV+ I +D ++YD E +  L+ RA NI EDLGQIQYVF DKTGTLTEN+M F+R  + G +Y+  D+     + ++ M  E  D++D+
Sbjct:   56 YAGNSIKTTKYTALSFLPKNLFEQFHRLANVYFVFMALLNFVPAVNAFKPELALAPVLFILAVTAIKDLWEDYRRYRSDKEINHMDCLVFCRSEKKYREKYWKEVQVGDFVQLRCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKQRQVLKGFVELESEFDP-MTFKSIIECEKPNNDLTRFRGYIHKNGKKSG--LFKENLLLRGCTIRNTEVVSGIVIYAGHETKALLNNNGPRYKRSKLERQMNKDVFWCVLILLIMCLFSAVGHALWV-----------WQYGEKRPVFDVLGSDGKYVKPFLSAVYLFFTMIIVLQVLIPVSLYVSIEIVKICQVYFIHQDKDLYDEETDSQLQCRALNITEDLGQIQYVFSDKTGTLTENKMVFRRCTVSGVEYSHDDN-----AKRLAMYQE-ADSEDE 465          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAM------FGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKT------------RPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPR 3891
            +E+ESPDE ALV  +  +   L+ R  + VT+  P   R + + +L  L FDS RKRMS++V+ P TD I+++ KGADS +      +    K   +I Q  T+ Y++ YA  GLR L + +RV+SK+ ++ W K + +AE  L N E+ L      +E+++ LLG +GIED LQ+GV +TI  LR+AGI +W+LTGDK+ETA+NI YS KL      LI L+A S E+   L+++ L  I+S + + + E   G T              L +  L L +DG TL FA++      FL LA +C SV+C R+TP+QK+ +V+LV++ LR  TLA+GDG NDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F++L++LLLVHG WCY++LA   LY FYK+ +++ L+FW+QF   FS S MID    + FN+  + +P +I G+ DKDL A+ L  NPELY++G N + YKP  FW+N++DA +QS V + I Y +F  SDI ++ +G  I  CAL+T ++HLG+ET+ WTW +   I  S IL +    ++Y   C    C    +PY  + + M   LF+L+C+++P+ A+ PR
Sbjct:  669 FEAESPDEAALVYASRAYNCALVGRLSDQVTVELPHLGR-LNFELLHTLGFDSVRKRMSVVVRHPLTDEIVVYAKGADSVILDLIQPYDRLGKHQRKI-QAKTQKYLNCYAVDGLRTLCIAKRVLSKEEYACWLKFHLQAESSLDNREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETITRLRKAGIQIWVLTGDKQETAVNIGYSCKLLDHEDDLITLNAESLEECSTLLEQCLHYIQSKFSSGLQEKVVGGTGIDSVQHNTLWPPNLKQSSLGLVIDGKTLAFALDITQSDKFLLLARKCRSVLCCRSTPLQKSLVVKLVRDKLRAMTLAVGDGTNDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRHLEKLLLVHGRWCYSRLANMVLYFFYKNAMFVALLFWYQFYCGFSGSAMIDQWYLIFFNLLFSSIPQLITGILDKDLPAELLTANPELYKSGPNMEEYKPHMFWLNMIDAFYQSLVCFFIPYFSFFDSDIDLFTWGTPIVTCALLTIMMHLGMETKTWTWINVSSIVFS-ILLFFTVALVYNSSCP--TCNPPSNPYWTMQKLMANPLFYLICILSPVTALLPR 1262          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTV--------IRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDK 1398
            YA N ++T KY A++F+P NLFEQFHR AN+YFVF+ +LNF+P + AF  E+A  PV+F+L+VTAIKD  EDYRR+++D+ +NH  CL++  ++K++ E+ W   + GDFV+L  NE IPADI+LL S+D  G+CHIET+NLDGE+NLKQR+V+   +E  + F P M   S IE E PN ++ +F G I    +  G  L K NLLLRGCT+RNTE V GIV+YAG ETKA+LNNN  R+KRSKLERQ+NKDV WCVL+L+I+CL  ++G+ +W            +++ +  P             P + A   F+T +I  Q LIP+ LYV+ E VK+ QV+ I +D ++YD E +  L+ RA NI EDLGQIQYVF DKTGTLTEN+M F+R  + G +Y+  D+     + ++ M  E  D++D+
Sbjct:   56 YAGNSIKTTKYTALSFLPKNLFEQFHRLANVYFVFMALLNFVPAVNAFKPELALAPVLFILAVTAIKDLWEDYRRYRSDKEINHMDCLVFCRSEKKYREKYWKEVQVGDFVQLRCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKQRQVLKGFVELESEFDP-MTFKSIIECEKPNNDLTRFRGYIHKNGKKSG--LFKENLLLRGCTIRNTEVVSGIVIYAGHETKALLNNNGPRYKRSKLERQMNKDVFWCVLILLIMCLFSAVGHALWV-----------WQYGEKRPVFDVLGSDGKYVKPFLSAVYLFFTMIIVLQVLIPVSLYVSIEIVKICQVYFIHQDKDLYDEETDSQLQCRALNITEDLGQIQYVFSDKTGTLTENKMVFRRCTVSGVEYSHDDN-----AKRLAMYQE-ADSEDE 465          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEID---------QENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKT------------RPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPR 3891
            +E+ESPDE ALV  +  +   L+ R  + VT+  P   R + + +L  L FDS RKRMS++V+ P TD I+++ KGADS +  +  +  S+ D         Q  T+ Y++ YA  GLR L + +RV+SK+ ++ W K + +AE  L N E+ L      +E+++ LLG +GIED LQ+GV +TI  LR+AGI +W+LTGDK+ETA+NI YS KL      LI L+A S E+   L+++ L  I+S + + + E   G T              L +  L L +DG TL FA++      FL LA +C SV+C R+TP+QK+ +V+LV++ LR  TLA+GDG NDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F++L++LLLVHG WCY++LA   LY FYK+ +++ L+FW+QF   FS S MID    + FN+  + +P +I G+ DKDL A+ L  NPELY++G N + YKP  FW+N++DA +QS V + I Y +F  SDI ++ +G  I  CAL+T ++HLG+ET+ WTW +   I  S IL +    ++Y   C    C    +PY  + + M   LF+L+C+++P+ A+ PR
Sbjct:  673 FEAESPDEAALVYASRAYNCALVGRLSDQVTVELPHLGR-LNFELLHTLGFDSVRKRMSVVVRHPLTDEIVVYAKGADSVIL-DLIQPCSKDDRLGKHQRKIQAKTQKYLNCYAVDGLRTLCIAKRVLSKEEYACWLKFHLQAESSLDNREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETITRLRKAGIQIWVLTGDKQETAVNIGYSCKLLDHEDDLITLNAESLEECSTLLEQCLHYIQSKFSSGLQEKVVGGTGIDSVQHNTLWPPNLKQSSLGLVIDGKTLAFALDITQSDKFLLLARKCRSVLCCRSTPLQKSLVVKLVRDKLRAMTLAVGDGTNDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRHLEKLLLVHGRWCYSRLANMVLYFFYKNAMFVALLFWYQFYCGFSGSAMIDQWYLIFFNLLFSSIPQLITGILDKDLPAELLTANPELYKSGPNMEEYKPHMFWLNMIDAFYQSLVCFFIPYFSFFDSDIDLFTWGTPIVTCALLTIMMHLGMETKTWTWINVSSIVFS-ILLFFTVALVYNSSCP--TCNPPSNPYWTMQKLMANPLFYLICILSPVTALLPR 1269          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTV--------IRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDK 1398
            YA N ++T KY A++F+P NLFEQFHR AN+YFVF+ +LNF+P + AF  E+A  PV+F+L+VTAIKD  EDYRR+++D+ +NH  CL++  ++K++ E+ W   + GDFV+L  NE IPADI+LL S+D  G+CHIET+NLDGE+NLKQR+V+   +E  + F P M   S IE E PN ++ +F G I    +  G  L K NLLLRGCT+RNTE V GIV+YAG ETKA+LNNN  R+KRSKLERQ+NKDV WCVL+L+I+CL  ++G+ +W            +++ +  P             P + A   F+T +I  Q LIP+ LYV+ E VK+ QV+ I +D ++YD E +  L+ RA NI EDLGQIQYVF DKTGTLTEN+M F+R  + G +Y+  D+     + ++ M  E  D++D+
Sbjct:   43 YAGNSIKTTKYTALSFLPKNLFEQFHRLANVYFVFMALLNFVPAVNAFKPELALAPVLFILAVTAIKDLWEDYRRYRSDKEINHMDCLVFCRSEKKYREKYWKEVQVGDFVQLRCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKQRQVLKGFVELESEFDP-MTFKSIIECEKPNNDLTRFRGYIHKNGKKSG--LFKENLLLRGCTIRNTEVVSGIVIYAGHETKALLNNNGPRYKRSKLERQMNKDVFWCVLILLIMCLFSAVGHALWV-----------WQYGEKRPVFDVLGSDGKYVKPFLSAVYLFFTMIIVLQVLIPVSLYVSIEIVKICQVYFIHQDKDLYDEETDSQLQCRALNITEDLGQIQYVFSDKTGTLTENKMVFRRCTVSGVEYSHDDN-----AKRLAMYQE-ADSEDE 452          

Query: 2032 IADTYSDINTEGDRNNSGID---SFKNDQDNKCPISDKDLLAS---YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF------------GNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQG-----------KTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            +  T   I + G  + +G +   + +   D KCP   ++       YE+ESPDE ALV  A  +   L+ R  + V++  P   R +T+ +L  L FDS RKRMS++++ P TD I ++ KGADS +             G   K I    +  T++Y++ YA  GLR L + +RV+SK+ ++ W + + EAE  + + E+ L      +E+++ LLG +GIED LQ+GV +TI  LR+AG+ +W+LTGDK+ETAINIAY+ KL    + +I L+A S+E    L+ + L  ++S  P   ++  +             T        +L +DG +L +A+E  ++  FL LA+QC SV+C R+TP+QK+ +V+LV+  L+  TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F+YL+RLL+VHG WCY++LA   LY FYK+T+++ L+FWFQF   FSAS MID    + FN+  + LP ++ GV DKD+ AD L+R P+LY++G N + Y+P  FW+N++DA +QS V + I Y+ +  SD+ ++ +G  +TA AL T L+HLGIET+ WTW + L    S  L + V  +IY   C      S +PY  +   +   LF+L C++ P+AA+ PRL    ++ SL+P  L  G
Sbjct:  662 LGQTAPSIASNGYASQAGQEESWASECTTDQKCPGEQREQQEGELRYEAESPDEAALVYAARAYNCALVDRLHDQVSVELPHLGR-LTFELLHTLGFDSIRKRMSVVIRHPLTDEINVYTKGADSVVMDLLLPCSSDDARGRHQKKI----RSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAEASVESREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSQEACAALLDQCLSYVQSRNPRSTLQNSESNLSVGFSFNPVSTSTDASPSPSLVIDGRSLAYALEKSLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVDVFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFLFFSV-ALIYNTSCATCYPPS-NPYWTMQTLLGDPLFYLTCLIAPIAALLPRLFFKALQGSLFPTQLQLG 1321          

Query:  142 ANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA--------VKDDETDGQSDKVTMRSEFGDTDDKKMNDDH 1416
            A+N ++T KY  ++F+P NLFEQFHR AN+YFVFI +LNF+P + AF   +A  PV+F+L+VTAIKD  EDY R ++D  +NH  CL++S  +K++V + W   R GDFV+L  NE IPADI+LL S+D  G+CHIET+NLDGE+NLK+R+VV    E  + F P +   S IE E PN ++ +F G I   S      L K NLLLRGCT+RNTE V GIV+YAG ETKA+LNN+  R+KRS+LERQ+N DV+WCVLLL+ + L  ++G+ +W      Q+    +  P+S  + + +PA  A  +F+T +I  Q LIP+ LYV+ E VK+ QV+ I +D+E+YD E +  L+ RA NI EDLGQI+Y+F DKTGTLTEN+M F+R  + G +Y+         +  E D + ++V   S+ G    +     H
Sbjct:   64 ADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSREEKKYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNP-LTFTSVIECEKPNNDLSRFRGYI-MHSNGEKAGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRR--YQEKKALFDVPESDGSSL-SPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLARYQEADSEEEEVV--SKVGTISHRGSTGSH 491          

Query: 1936 GDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSDINTEGDRNNSGID------SFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISE--IDQEN--------TKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNY--------------PNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSD-DPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            G+++  +  +ID+  + D          +  Y + T+   +  G  + + ++      +   D+   C          YE+ESPDE ALV  A  + + L+ R P  VT+  P+    +T+ +L  L FDS RKRMS++V+ P TD II++ KGADS +         E  ID E         T+ ++D YAR GLR L + ++V+ ++ F  W    +EAE  L N E+ L+     +E+ + LLG +GIED LQ+GV DTI +LR AGI +W+LTGDK+ETA+NIAYS KL  +   +  ++  ++E    ++   L +IK  +              P ++  +  G   P    ++ L +DG TL    + +++  FL L + C SV+C R+TP+QK+ IV+LV++ L + TL+IGDGANDVSMIQ AD+G+GI G EGMQAVM+SDFA+ +F +LK+LLLVHG WCY++LAR  +Y FYK+  Y+ L+FW+QF   FS S MID    + FN+  T LPPII+GV DKD+ A+TL+  PELY++G N + Y    FWV++ DA +QS + + I Y+T+  SDI ++ FG  I   +L T L+H  +E + WT  HGL +  SF++ + V ++IY   C  V C S  +PY  + + +    F+L+C++TP+ A+ PR  + +++ +   +L+ K 
Sbjct:  619 GESLGPNLPTIDSDEKDDTSVCSGDCSTDGGYRSSTWEQGDILGSESGTSLEEGLEAPTLSQDEPELC----------YEAESPDEAALVHAARAYSFTLVSRTPEQVTVRLPQG-ICLTFDLLFTLGFDSVRKRMSVVVRHPLTDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKRFHEPQQPARKLCGHRIPPKMPSVNSGAMAP----EIGLVIDGKTLNAIFQGKLENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLM-YFVVSLIYNATC--VTCNSPTNPYWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKA 1301          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKF--PDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDD 1335
            Y  N+V+T KY  ++FIP NLFEQ HRFAN+YFV I+ILNF+P + AF   V+ +PV  +L+VTAIKDA ED+RR+K+D+ +N+ + L+YS  +++++ ++W   R GDFV++  NE +PADI+LL S+D SG+CH+ET+NLDGE+NLKQR VV    +    F+PE   +S I  E PN  + KF G +    Q+        +LLLRGCT+RNTE   GIV+YAG ETKAMLNN+  R+KRSK+ER+IN D+ +C+ LL ++CL  ++G+ +W  T     F E+  F  PD+    + + A+  F  F T +I  Q LIP+ LYV+ E VK+ QVF +  DL++YD E +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  I G +Y  +++
Sbjct:   38 YRGNQVKTSKYTVLSFIPKNLFEQLHRFANLYFVGIVILNFIPVVNAFQPGVSMVPVCAILTVTAIKDAWEDFRRYKSDKVINNRESLVYSRKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEHF-HSTIVCEKPNNHLSKFKGYMEHPDQT-RTGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGT-----FKEHPPFDVPDADGNFL-SLALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGSEYCHQEN 432          

Query: 1936 GDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSDINTEGDRNNSGID------SFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISE--IDQEN--------TKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNY--------------PNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSD-DPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            G+++  +  +ID+  + D          +  Y + T+   +  G  + + ++      +   D+   C          YE+ESPDE ALV  A  + + L+ R P  VT+  P+    +T+ +L  L FDS RKRMS++V+ P TD II++ KGADS +         E  ID E         T+ ++D YAR GLR L + ++V+ ++ F  W    +EAE  L N E+ L+     +E+ + LLG +GIED LQ+GV DTI +LR AGI +W+LTGDK+ETA+NIAYS KL  +   +  ++  ++E    ++   L +IK  +              P ++  +  G   P    ++ L +DG TL    + +++  FL L + C SV+C R+TP+QK+ IV+LV++ L + TL+IGDGANDVSMIQ AD+G+GI G EGMQAVM+SDFA+ +F +LK+LLLVHG WCY++LAR  +Y FYK+  Y+ L+FW+QF   FS S MID    + FN+  T LPPII+GV DKD+ A+TL+  PELY++G N + Y    FWV++ DA +QS + + I Y+T+  SDI ++ FG  I   +L T L+H  +E + WT  HGL +  SF++ + V ++IY   C  V C S  +PY  + + +    F+L+C++TP+ A+ PR  + +++ +   +L+ K 
Sbjct:  647 GESLGPNLPTIDSDEKDDTSVCSGDCSTDGGYRSSTWEQGDILGSESGTSLEEGLEAPTLSQDEPELC----------YEAESPDEAALVHAARAYSFTLVSRTPEQVTVRLPQG-ICLTFDLLFTLGFDSVRKRMSVVVRHPLTDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKRFHEPQQPARKLCGHRIPPKMPSVNSGAMAP----EIGLVIDGKTLNAIFQGKLENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLM-YFVVSLIYNATC--VTCNSPTNPYWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKA 1329          

Query:   70 NGEEQCRKIYPSTS-TNSNFEKY--KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKF--PDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDD 1335
            N  EQ R +YP+ S  + +++K   +Y  N + T KY  +TF+P NLFEQFHR+AN+YF+F++ILN++P +E F +E+   P+  VL +  +KD +ED++R+  D+ +N +   IY   +++++ ++W   R GDFV++  NE +PADI+LL S+D SG+CH+ET+NLDGE+NLKQR VV    +    F+PE   +S I  E PN  + KF G +    Q+        +LLLRGCT+RNTE   GIV+YAG ETKAMLNN+  R+KRSK+ER+IN D+ +C+ LL ++CL  ++G+ +W  T     F E+  F  PD+    + + A+  F  F T +I  Q LIP+ LYV+ E VK+ QVF +  DL++YD E +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  I G +Y  +++
Sbjct:   41 NTAEQ-RVVYPNNSMCHQDWKKVCRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITIFPLATVLLIIMVKDGIEDFKRYCFDREMNSASIQIYERKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEHF-HSTIVCEKPNNHLSKFKGYMEHPDQT-RTGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGT-----FKEHPPFDVPDADGNFL-SLALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGSEYCHQEN 460          

Query: 2020 ELSYIADTYSDINTEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISE--------IDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNI--KSNYPNEIMEIRQGKTRPLIRKD---LALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            E+   +++     TE      G+     +  +  P S  +L   YE+ESPDE ALV  A  +   L  R P  V + +  +   +T+ +L +LPFDS RKRMS++V+ P +  ++++ KGADS +    S   S+        I +E T+ ++D YA+ GLR L + ++V+S   ++EW + +  AE  + N E+ L+     +E+ + LLG +GIED LQ+GV ++IE+L +AGI +W+LTGDK+ETA+NIAY+ KL   + +L  L+  S++    L+   L  +  ++    E+   R+   +P   +      L + G TL FA+++ ++  FL L   C +V+C R TP+QK+E+V+LV+ +L + TLAIGDGANDVSMIQ+AD+G+G+ G EGMQAVMASDFA+++F++L +LLLVHG WCY +L+   LY FYK+  Y+ L+FW+QF   FS + M D    + FN+  T +PPIIYGV +KD+ A+TL++ PELYR+G   + Y P  FW+ +LDA +QS V + + Y T+  SDI I+ FG  +   AL   L+HL IE++  TW H L + +  IL++  F + +  +C  V C    +PY  + ++M   +F+L+CV+T   A+ PR     ++ S++P+ + + 
Sbjct:  733 EIPQASNSACCTETEAQNRAVGLSVSSAEALSGPPPSASNL--CYEAESPDEAALVYAARAYRCTLQSRTPEQVMV-DFAALGSLTF*LLHILPFDSVRKRMSVVVRHPLSKQVVVYTKGADSVIMELLSVAASDGTNPEQQMIIRERTQRHLDEYAKRGLRTLCVAKKVMSDTEYAEWLRNHFLAETSIDNREELLVESAMRLENKLTLLGATGIEDRLQEGVPESIEALHQAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSQDACGMLMSAILEELQKRAQVSPELASSRKNFPQPSDAQGQGRAGLVITGKTLEFALQESLQRQFLELTAWCQAVICCRATPLQKSEVVKLVRNHLHVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAISQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSVPPIIYGVLEKDVSAETLLQLPELYRSGQRSEEYLPLTFWITLLDAFYQSLVCFFVPYFTYQGSDIDIFTFGNPLNTAALFIILLHLVIESKSLTWIHML-VTVGSILSYFFFALAFGALC--VTCNPPSNPYGIMRKHMLDPVFYLVCVLTTFVALLPRFLYRVLQGSVFPSPVLRA 1382          

Query:  124 FEKYK--YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQS--DKVTMRSEFGDT 1389
            +E++   Y NN +RT KY  + F+P NLFEQFHR AN+YF+F+++LN++P +EAF KE+  +P+V VL++ AIKD +EDYR++K D+++N+    +YS  +K++++  W +   GDF++L  NE IPAD+VLL S D  GICHIETS LDGESNLKQR+VV    E ++   PE  S S IE E+PN ++ +F G +   ++   + L K NLLLRGCT+RNTE V+GIVVYAG ETKAMLNN+  R+KRSKLER+ N DV+WCVLLLI++CL+ ++G+ IW   S  ++ + ++  P+    VI +P +  F  FWT +I  Q LIP+ LYV+ E VK+ Q++ I+ D++ Y+ + +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  + G DY  +++    +S  + V+   E  DT
Sbjct:  117 YERFSGTYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDCCWKNVTVGDFIRLSCNEIIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYTEQDSEVDPEKFS-SRIECESPNNDLSRFRGFLEHANKE-RVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVLLLIVMCLTGALGHGIW--LSRYENML-FFNIPEPDGRVI-SPVLTGFYVFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSTIQCRALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRLESYQEAVSEEEECTDT 538          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEF---LGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWE--------FGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLL 3936
            Y++ SPDE ALVK A   G+    R P  V I     E+  T+ +L VL F S+RKRMS+IV+ P +  + ++CKGAD+ +F   SKD   +  E T  +++ +A  GLR L +    +S++ + EW K Y+EA   L +  + L      IE +++LLG + IED LQ GV +TI +L +A I +W+LTGDK+ETAINI YS +L S+N  LI L   S + T   I +    LGN+             GK       D+AL +DG TL +A+  E++  FL LA  C +V+C R +P+QK+EIV +VK+ ++  TLAIGDGANDV MIQ A VGVGI GNEGMQA   SD+A+ +F YL++LLLVHG+W YN++ +  LY FYK+ +  ++  WF F N FS  ++ +     L+N+  T LPP   G++++    ++++R P+LYR   N + +    FW + ++A+  S +++ +  +  +  D  +           G I+    ++T  +  G+ET  WT F  L ++ S +L WLVF  +Y+ I   +    D         +    FWL   + P A +   +     +++    LL
Sbjct:  481 YQASSPDEAALVKGAKKLGFVFTGRTPYSVIIEAMGQEQ--TFGILNVLEFSSDRKRMSVIVRLP-SGQLRLYCKGADNVIFERLSKDSKYM--EETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASIILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQHCTDLGNL------------LGK-----ENDVALIIDGHTLKYALSFEVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYRITQNAEGFNTKVFWGHCINALVHSLILFWV-PMKALEHDTPVTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGS-MLIWLVFFGVYSTIWPTIPIAPDMKGQATMV-LSSAYFWLGLFLVPTACLIEDVAWRAAKHTCKKTLL 1061          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLS-NSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNE 1566
            K+ +N + T KY+ +TF+P  L+EQ  R AN +F+FI +L  +P++   G+    +P+V +L++  IK+ +ED++R KAD  VN  K ++        +   W     GD VK+   + +PAD+VL  S++  G+C++ET+NLDGE+NLK R+ +    +   +  ++  +  IE E PN+ +Y F G +    +S  + L  + +LLRG  LRNT+ V G+VVY G ++K M N+     KRS +E+  N  ++    +L+++ L  S+G + W  +   + +  Y K  D+      N     +    T +I Y  LIP+ L VT E VK  Q   I  D++MY  E +     R  N+ E+LGQ++Y+F DKTGTLT N M FK+  I G  Y    +    QS     R      D    ND    +LLKN+           E++      +++F  L+ +C+T V   + +E
Sbjct:   27 KFCDNRISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLVIILTIAGIKEIIEDFKRHKADNAVNKKKTIVLRNGMWHTI--MWKEVAVGDIVKVLNGQYLPADMVLFSSSEPQGMCYVETANLDGETNLKIRQGLSHTTDMQTRDVLMKLSGRIECEGPNRHLYDFTGNLHLDGKS-SVALGPDQILLRGTQLRNTQWVFGVVVYTGHDSKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSVGALFWNGSHGGKSW--YIKKMDT------NSDNFGY-NLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDMDMYYIENDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGHFPELAREQSSDDFCRMTSCTNDSCDFND---PRLLKNI-----------EDQHPTAPCIQEFLTLLAVCHTVVPEKDGDE 478          

Query: 2032 IADTYSDINTEGDRNNSGID---SFKNDQDNKCPISDKDLLAS---YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF------------GNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQG-----------KTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            +  T   I + G  + +G +   + +   D KCP   ++       YE+ESPDE ALV  A  +   L+ R  + V++  P   R +T+ +L  L FDS RKRMS++++ P TD I ++ KGADS +             G   K I    +  T++Y++ YA  GLR L + +RV+SK+ ++ W + + EAE  + + E+ L      +E+++ LLG +GIED LQ+GV +TI  LR+AG+ +W+LTGDK+ETAINIAY+ KL    + +I L+A S+E    L+ + L  ++S  P   ++  +             T        +L +DG +L +A+E  ++  FL LA+QC SV+C R+TP+QK+ +V+LV+  L+  TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F+YL+RLL+VHG WCY++LA   LY FYK+T+++ L+FWFQF   FSAS MID    + FN+  + LP ++ GV DKD+ AD L+R P+LY++G N + Y+P  FW+N++DA +QS V + I Y+ +  SD+ ++ +G  +TA AL T L+HLGIET+ WTW + L    S  L + V  +IY   C      S +PY  +   +   LF+L C++ P+AA+ PRL    ++ SL+P  L  G
Sbjct:  662 LGQTAPSIASNGYASQAGQEESWASECTTDQKCPGEQREQQEGELRYEAESPDEAALVYAARAYNCALVDRLHDQVSVELPHLGR-LTFELLHTLGFDSIRKRMSVVIRHPLTDEINVYTKGADSVVMDLLLPCSSDDARGRHQKKI----RSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAEASVESREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSQEACAALLDQCLSYVQSRNPRSTLQNSESNLSVGFSFNPVSTSTDASPSPSLVIDGRSLAYALEKSLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVDVFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFLFFSV-ALIYNTSCATCYPPS-NPYWTMQTLLGDPLFYLTCLIAPIAALLPRLFFKALQGSLFPTQLQLG 1321          

Query:  142 ANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA--------VKDDETDGQSDKVTMRSEFGDTDDKKMNDDH 1416
            A+N ++T KY  ++F+P NLFEQFHR AN+YFVFI +LNF+P + AF   +A  PV+F+L+VTAIKD  EDY R ++D  +NH  CL++S  +K++V + W   R GDFV+L  NE IPADI+LL S+D  G+CHIET+NLDGE+NLK+R+VV    E  + F P +   S IE E PN ++ +F G I   S      L K NLLLRGCT+RNTE V GIV+YAG ETKA+LNN+  R+KRS+LERQ+N DV+WCVLLL+ + L  ++G+ +W      Q+    +  P+S  + + +PA  A  +F+T +I  Q LIP+ LYV+ E VK+ QV+ I +D+E+YD E +  L+ RA NI EDLGQI+Y+F DKTGTLTEN+M F+R  + G +Y+         +  E D + ++V   S+ G    +     H
Sbjct:   64 ADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSREEKKYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNP-LTFTSVIECEKPNNDLSRFRGYI-MHSNGEKAGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRR--YQEKKALFDVPESDGSSL-SPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLARYQEADSEEEEVV--SKVGTISHRGSTGSH 491          

Query: 2128 SDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEID---------QENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGK------------TRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLL 3936
            S+++L   YE+ESPDE ALV  A  +   L++R  + V++  P   R +T+ +L  L FDS RKRMS++++ P TD I ++ KGADS +  +  +  S +D         +  T++Y++ YA  GLR L + +RV+SK+ ++ W + + EAE  L N+E+ L      +E+++ LLG +GIED LQDGV +TI  LR+AG+ +W+LTGDK+ETA+NIAY+ KL   ++ +I L+A+S+E    L+ + L  ++S       E  +GK            T     +  +L +DG +L +A+E  ++  FL LA+QC SV+C R+TP+QK+ +V+LV+  L+  TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ KF+YL+RLL++HG WCY++LA   LY FYK+T+++ L+FWFQF   FSAS MID    + FN+  + LPP++ GV D+D+ A+ L+ NP+LY++G N + Y+P  FW N+ DA +QS V + I Y+ +  S++ ++ +G  I   AL+T L+HLGIET+ WTW + +    S +L + V  +IY   C      S +PY  +   +   +F+L C++TP+AA+ PRL   +++  ++P  L
Sbjct:  687 SEREL--RYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVM-DLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTV-ALIYNASCATCYPPS-NPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQL 1304          

Query:   52 NLIPKKNGEEQCRKIYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA--------VKDDETDGQSDKVTMR 1371
            NL+P    E+                    A+N ++T KY  ++F+P NLFEQFHR AN+YFVFI +LNF+P + AF   +A  PV+F+L++TA +D  EDY R ++D ++NH  CL++S  +K++V + W     GDFV+L  NE  PADI+LL S+D  G+CHIET+NLDGE+NLK+R+VV    E  + F P +   S IE E PN ++ +F G I   +      L K NLLLRGCTLRNT+ V+GIV+YAG ETKA+LNN+  R+KRSKLERQ+N DV+WCVLLL+ + L  ++G+ +W      Q+    +  P S  + + +P   A  +F T +I  Q LIP+ LYV+ E VK  QV+ I +D+++YD E +  L+ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  + G +Y+         +  E D + ++V  R
Sbjct:   30 NLLPPPGAEDPAAGAAKGERRRRRGCAQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNP-LTFTSVIECEKPNNDLSRFRGCIIHDNGKKA-GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWR--YQEKKSLFYVPKSDGSSL-SPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPR 474          

Query: 2059 TEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSA---MFGNFSKDISEIDQ------ENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNI--KSNYPNEIMEIRQGKTRPLIRKDLALS----VDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            TE    ++G+ + K +     P++       YE+ESPDE ALV  A  +   L  R P  V + +  +  P+T+ +L +LPFDS RKRMS++V+ P ++ ++++ KGADS    +    S D + +++      E T+ ++D YA+ GLR L + ++V+S   ++EW + +  AE  + N E+ LL     +E+ + LLG +GIED LQ+GV ++IE+L +AGI +W+LTGDK+ETA+NIAY+ KL   + +L  L+  SK+    L+   L  +  K+    E + + +   +P + +D  L     + G TL FA+++ ++  FL L   C +VVC R TP+QK+E+V+LV+ +L++ TLAIGDGANDVSMIQ+AD+G+G+ G EGMQAVMASDFA+++FK+L +LLLVHG WCY +L+   LY FYK+  Y+ L+FW+QF   FS + M D    + FN+  T  PP+IYGV +KD+ A+TLM+ PELYR+G   ++Y P  FW+ +LDA +QS V + + Y T+  SD  I+ FG  +   AL   L+HL IE++  TW H L + I  IL++ +F +++  +C  V C    +PY  + ++M   +F+L+C++T   A+ PR     ++ SL+P+ + + 
Sbjct:  695 TEKQHGDAGLLNGKAESLPGQPLACN---LCYEAESPDEAALVYAARAYQCTLRSRTPEQVMV-DFAALGPLTFQLLHILPFDSVRKRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKELQKKTQALPEQVSLSEDLLQPPVPRDSGLRAGLIITGKTLEFALQESLQKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQGSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIH-LLVIIGSILSYFLFAIVFGAMC--VTCNPPSNPYWIMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQGSLFPSPILRA 1332          

Query:   61 PKKNGEEQCRKIYPSTST-NSNFEKYK--YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQS--DKVTMRSEFGDT 1389
            PK +G    R + P        +EK+   Y NN +RT KY  + F+P NLFEQFHR AN+YF+F+++LN++P +EAF KE+  +P+V VL++ AIKD +EDYR++K D+++N+    +YS  +K+++++ W     GDF++L  NE IPAD+VLL S D  GICHIETS LDGESNLKQR+VV    E ++   PE  S S IE E+PN ++ +F G     S    + L K NLLLRGCT+RNTE V+GIVVYAG ETKAMLNN+  R+KRSKLER+ N DV+WCV+LL+I+CL+ ++G+ IW ++ + +  + ++  P+    +I +P +  F  FWT +I  Q LIP+ LYV+ E VK+ Q++ I+ D++ Y+ + +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  + G DY  +++    +S  + V+   +F DT
Sbjct:   44 PKLSGRH--RIVVPHIQPFKDEYEKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFS-SRIECESPNNDLSRFRG-FLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIW-LSRYEK--MHFFNVPEPDGHII-SPLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRLESYQEAVSEDEDFIDT 485          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFG-----------NFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKS----NYPN-EIMEIRQGKTRPLIRKDL-----ALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSD-DPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            YE+ESPDE ALV  A  + + L+ R P  VT+  P+    +T+++L  L FDS RKRMS++V+ P T  I+++ KGADS +             N  K + +I +  T+ ++D YAR GLR L + ++V+S++ F  W    +EAE  L N ++ L+     +E+ + LLG +GIED LQ+GV DTI +LR AGI +W+LTGDK+ETA+NIA+S +L ++   +  ++  ++E    ++   L  +K       P+ ++   R     P I  +       L +DG TL    + +++  FL L + C SV+C R+TP+QK+ IV+LV++ LR+ TL+IGDGANDVSMIQ AD+G+GI G EGMQAVM+SDFA+T+FK+LK+LLLVHG WCY++LAR  +Y  YK+  Y+ L+FW+QF   FS+S MID    + FN+  T LPP+++GV DKD+ A+TL+  PELY++G N + Y    FW++++DA +QS + + I Y+ +  SDI ++ FG  I   +L T L+H  +E + WT FHG+ +  SF++ +LV +++Y   C  V+C S  +PY  +   +    F+L+C +TP+ A+ PR    +++ +   +L+ K 
Sbjct:  717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGT-CLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKI-RARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLV-SLLYNATC--VICNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKA 1331          

Query:   82 QCRKIYPSTST-NSNFEKY--KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKF--PDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA----------VKDDETDGQ---------------SDKVTMRSEFGDTDDKK-------MNDDHGKKLL-----------------------KNLIPMLH---------GDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPV 1578
            Q R ++P+ S  + ++E+   +Y  N   T KY   TF+P NLFEQFHR+AN+YF+F++ILN++P +E F +E+  +P+  VL V  IKD +ED++R + D+ +N S   IY   ++ +V++ W   R GDF+++  NE +PADI+LL S+D +GICH+ET++LDGE+NLKQR VV    +    F+PE+  N+ +  E PN  + KF G +    Q+        +LLLRGCT+RNTE  +GIV+YAG ETKAMLNN+  R+KRSK+ER++N D+ +C+ +LI++CL  ++G+ IW  T     F E+  F  PD+  + + + A+  F  F T +I  Q LIP+ LYV+ E VK+ QVF +  DL++YD E +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  I G +Y+           K+ ++DG+                D  TMRS+ G    ++       +   + ++ +                       KNL+  +           D    +  +S   ++ DFFL + ICN+ +VS     +  V
Sbjct:   44 QQRVVFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIV-CEKPNNHLNKFKGYMEHPDQT-RTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGT-----FEEHPPFDVPDANGSFLPS-ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQYQCLSFSARWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQPPVAFSSSIEKDVTPDKNLLTKVRDAALWLETLSDSRPAKASLSTTSSIADFFLALTICNSVMVSTTTEPRQRV 605          

Query: 2020 ELSYIADTYSDINTEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISE--------IDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNI--KSNYPNEIMEIRQGKTRPLIRKD---LALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            E+   +++     TE      G+     +  +  P S  +L   YE+ESPDE ALV  A  +   L  R P  V + +  +   +T+ +L +LPFDS RKRMS++V+ P +  ++++ KGADS +    S   S+        I +E T+ ++D YA+ GLR L + ++V+S   ++EW + +  AE  + N E+ L+     +E+ + LLG +GIED LQ+GV ++IE+L +AGI +W+LTGDK+ETA+NIAY+ KL   + +L  L+  S++    L+   L  +  ++    E+   R+   +P   +      L + G TL FA+++ ++  FL L   C +V+C R TP+QK+E+V+LV+ +  + TL IGDGANDVSMIQ+AD+G+G+ G EGMQAVMASDFA+++F++L +LLLVHG WCY +L+   LY FYK+  Y+ L+FW+QF   FS + M D    + FN+  T +PPIIYGV +KD+ A+TL++ PELYR+G   + Y P  FW+ +LDA +QS V + + Y T+  SDI I+ FG  +   AL   L+HL IE++  TW H L + +  IL++  F + +  +C  V C    +PY  + ++M   +F+L+CV+T   A+ PR     ++ S++P+ + + 
Sbjct:  680 EIPQASNSACCTETEAQNRAVGLSVSSAEALSGPPPSASNL--CYEAESPDEAALVYAARAYRCTLQSRTPEQVMV-DFAALGSLTFQLLHILPFDSVRKRMSVVVRHPLSKQVVVYTKGADSVIMELLSVAASDGTNPEQQMIIRERTQRHLDEYAKRGLRTLCVAKKVMSDTEYAEWLRNHFLAETSIDNREELLVESAMRLENKLTLLGATGIEDRLQEGVPESIEALHQAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSQDACGMLMSAILEELQKRAQVSPELASSRKNFPQPSDAQGQGRAGLVITGKTLEFALQESLQRQFLELTAWCQAVICCRATPLQKSEVVKLVRNHHHVLTLPIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAISQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSVPPIIYGVLEKDVSAETLLQLPELYRSGQRSEEYLPLTFWITLLDAFYQSLVCFFVPYFTYQGSDIDIFTFGNPLNTAALFIILLHLVIESKSLTWIHML-VTVGSILSYFFFALAFGALC--VTCNPPSNPYGIMRKHMLDPVFYLVCVLTTFVALLPRFLYRVLQGSVFPSPVLRA 1329          

Query:  124 FEKYK--YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQS--DKVTMRSEFGDT 1389
            +E++   Y NN +RT KY  + F+P NLFEQFHR AN+YF+F+++LN++P +EAF KE+  +P+V VL++ AIKD +EDYR++K D+++N+    +YS  +K++++  W +   GDF++L  NE IPAD+VLL S D  GICHIETS LDGESNLKQR+VV    E ++   PE  S S IE E+PN ++ +F G +   ++   + L K NLLLRGCT+RNTE V+GIVVYAG ETKAMLNN+  R+KRSKLER+ N DV+WCVLLLI++CL+ ++G+ IW   S  ++ + ++  P+    VI +P +  F  FWT +I  Q LIP+ LYV+ E VK+ Q++ I+ D++ Y+ + +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  + G DY  +++    +S  + V+   E  DT
Sbjct:   64 YERFSGTYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDCCWKNVTVGDFIRLSCNEIIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYTEQDSEVDPEKFS-SRIECESPNNDLSRFRGFLEHANKE-RVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVLLLIVMCLTGALGHGIW--LSRYENML-FFNIPEPDGRVI-SPVLTGFYVFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSTIQCRALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRLESYQEAVSEEEECTDT 485          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPT--------VIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVIXXXXXXXXXXXXXXXXXAGEGVMNKAASISSFSAKNIFTKSGKVSMKNSDNTEIESKVHDVLFDRNDHSLELLNFKRNDSALPDFDDIHIRITDTNQKDYVQTPNKSRK----------VKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVHIE---LSYIADTYSDINTEGDRNNSGIDSFKN---DQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQEN-------TKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKS----NYPNEIMEIRQ----------------GKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWL----FWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            YANN+++T KY  ++F+P NLFEQFHRFAN+YFVFI +LNF+P + AF  E+A  PV+F+LSVTAIKD  EDYRR ++D+ +NH  CL+YS  +K+++E+ W   R GDF++L  NE +PAD++LL S+D   +CHIET+ LDGE+NLKQR+VV   ++ +  F P +  NS IE E PN ++ +F G I   S      L K+NLLLRGCT+RNTEE +GI++YAG ETKAMLNNN  R+KRSKLERQ+N DV WCV++L+++CL  +IG+ +W            +++ D  P            +P + A   F T +I +Q LIP+ L+V+ E VK+ QV+ I +D E+YD E +  L+ RA NI EDLGQ+QY+F DKTGTLTEN+M F+R  + G +Y+      D  + ++ M  E  D++++                  HG    + + ++  ++ K     M   +          K                         +++K  + SS   K+I      +   N  ++++E       F R  HS  +   K+    L D  D  I +T  N    V +PN+ R+          VK++ DF         T   ++ + + L TN+ S  +    LS    T + +N E   ++    +F     + D    ++  +    YE+ESPDE ALV  A  +   L+ R P+ VT+  P   R +T+ +L  L FDS RKRMS++VK P TD I ++ KGADS +          +  +        T++Y++ YA  GLR L + ++V+SK+ ++ W + + EAE  +   E+ L      +E+++ LLG +GIED LQDGV +TI SLR+AG+ +W+LTGDK+ETAINIAY+ KL    + +I L+A S+E    L++  L  I++    N P +    +                   T P +   L L +DG TL +A++  ++  FL +A  C SV+C R+TP+QK+ +V+LV+  L++ TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F+YL++LLLVHG WCY++LA   LY FYK+ +++ L+FW+QF   FS S M+D    + FN+  +  P +I G  DKD+ ADTL   P+LY NG N + YKP+ FW+N++DA +QS + + I Y  ++ SD+ ++ +G  IT  AL T L+HLGIET+ WTW + + I  S  L + V  + Y   C      S+      +  MQR L    F+LLCVVTP+AA+ PR      + SL+PN +  G
Sbjct:   52 YANNKIKTTKYTLLSFLPKNLFEQFHRFANVYFVFIALLNFVPVVNAFQPELAIAPVIFILSVTAIKDLWEDYRRHRSDKEINHMDCLVYSRNEKKYLEKYWKEVRVGDFIRLRCNEILPADVLLLSSSDPDRLCHIETATLDGETNLKQRQVVRSFIDLDCEFDP-LKYNSVIECEKPNNDLNRFRGYIIHCSGRRD-GLYKDNLLLRGCTIRNTEEAVGIIIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFSAIGHGLWM-----------FQYGDKRPVFDVLSPEGTDLSPVVSAIYLFLTMIIVFQILIPISLFVSIEIVKICQVYFIHQDAELYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYS-----HDANARRLAMYQEM-DSEEEDCTS--------------HGGTLPRRDSVASHQSGKVVLRSMSTKSHRRTGSRAEAKR----------------------ASILSKHTAFSSPMEKDITPDPQLMDKVNECSSQME-------FMRF-HSQSI---KQIPPDLCDIFDFFIALTICNTV-VVSSPNQPRQKVRRYELKSPVKTIEDFIKRFTPSRLTSGSNSSSSSSLATNRSSHRVGSSMLSSAESTLTKLNEEKPPDHDLQHAFSPVPPNYDKTKALAKDECELRYEAESPDEAALVYAARAYKCSLVGRLPDQVTVELPHLGR-LTFELLHTLGFDSTRKRMSVVVKHPLTDQITVYTKGADSVIMDLIRPVTDNVKGKRQRKILYKTQNYLNLYAADGLRTLCIAKKVLSKEEYASWLQHHLEAETAIQKREELLFESALRLETNLHLLGATGIEDRLQDGVPETIASLRKAGLQIWVLTGDKQETAINIAYACKLLDPEEEIITLNADSQEACAVLLENSLHYIQTKFLCNPPPDPQAAKHYSSFHFSSPVCSLASSAHTSPFLVHRLGLVIDGRTLAYALDKSLEDKFLAVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFRYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMVDQWYLIFFNLMFSAFPQLITGTLDKDVSADTLQELPQLYMNGQNSEEYKPYMFWMNMIDACYQSLICFFIPYFAYVDSDVDLFTWGTPITTLALFTILIHLGIETKTWTWINWVSIGFSISLFFTV-ALCYNASCPTCFSPSN-----AYWTMQRLLGDPMFYLLCVVTPMAALLPRYFYRACQGSLFPNPVQVG 1303          

Query:   61 PKKNGEEQCRKIYPSTSTNSNFEKYKYAN-----NEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREV--VMMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVIXXXXXXXXXXXXXXXXXAGEGVMNKAASISSFSAKNIFTKSGKVSMKNSDNTEIESKVHDVLFDRNDHSLELLNFKRNDSALPDFDDIHIRITDTNQKDYVQTPNKSRKVKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSDINTE-----GDRNNSGIDSFKNDQDNK--CPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFS--KDISEIDQ--ENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQ---GKTRPLIRK--------DLALSVDGSTLTFAMEDE--IKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVC-GSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLI---REEKLGKG 3975
            P+   EE+ R + P+ +      + ++ N     N+VRT KY  ++F+P NL EQFHR AN+YF+FI++LN+ P I AFGKE+A IPV+FVL VTA+KD  ED RR  +D+RVN+S C IY     ++ +  W   R GD + L  NE +PADI+LL ++  +G+C+I+T +LDGE+NLKQREV    ++    F+P     S IEV+ P  +IY+F+G +   S +  + +   NLLLR C L+NT+ V GIVVYAG ETKAMLNN   R+KRS LERQ+N+DV WCVL+L+ILC+  ++G  +W + ++ Q   E +K   S      + + +AFLAFWT +I  Q +IPL LYVT E  K+ QV+HI  ++++YD E +K +E RA NI E+LGQ+QY+F DKTGTLTENRM F+R  I G DY   + E +G+  K +            ++     KL ++L   L     I ++  +    +++F LL+ +CNT V S      HP                       +MN +  I + S  N+F  SG   + + D T+ + ++H      ND   E L   R+ +  P  +                T N S +   V              S+  IN  +   N + +    +  +     +N       G++ N    +  ++Q  K  C  +  D    +E+ESPDE+ALV  A  +  +LL+R P  V +  P  E  + Y +LQVLPFDS RKRMSII++ P T+ I ++CKGADS++  N +  +D SE  Q    T+  +  YA  GLR+L+M +R++S   +++W   ++E +    N + +L    S +E  + LLG +GIED LQ+GV +T+ SL  +GI VW+LTGDK+ETAINIA+SAKLF+ +  ++++ A SK+   D IK +L  I+    +   + R      T  L+R+          AL VDG +LT+ ++    +   FL L   C SV+C R TP+QKA IV++VKE L+M+TLAIGDGANDVSMIQ ADVG+GI G EGMQAVMA+DFA++KFKYL+R LLVHG W Y++LAR  LY FYK+  ++ L+FW+Q    FS ++MID +  +L+N+  T LPP+  GV+D+D   D L + P LYR G   K Y+ + FW+ + DA++QS  I+ IC   +M + I IWEFG  +T   +     H+ IE + WT  H   I IS I A+ V++++Y  +C  V C G    Y  I   +    +WL  +++ + A+ PRL    I+N++ P+ + + LI   R+ + G+G
Sbjct:  164 PRSEQEERYRIVVPNHTVPPKTPRKEHPNGNRPNNKVRTTKYTLLSFLPRNLLEQFHRVANLYFIFIVLLNWFPAINAFGKEIAMIPVLFVLGVTAVKDLFEDRRRHASDKRVNNSTCRIYQSEAARYKKVLWKELRVGDLIHLSNNEVVPADILLLRTSAPNGVCYIDTGHLDGETNLKQREVPRTFLKKQEIFEPSKF-RSHIEVDAPTTKIYRFHGAMLHPSGAREV-VGTENLLLRECLLKNTDYVEGIVVYAGHETKAMLNNGGPRYKRSALERQMNQDVFWCVLVLVILCVIGAVGCKLW-LQAYNQ-IKEPFKLEAS------SESTEAFLAFWTYIIILQIMIPLSLYVTLEMCKIIQVYHIHHNVDLYDTETDKRVECRALNITEELGQVQYIFSDKTGTLTENRMIFRRCTIAGVDYNHHNLENEGRGAKAS----------AALSVIINPKLKEDLDSQLSEQSTIAQQRHA--ARIQEFLLLLAVCNTVVCS-----HHPHC--------------------DLMNASGVIEAVS--NVFATSGSARLNSIDCTDRDGQMHST----ND-KYERLKESRSVTPSPPLNS--------------HTHNDSLRATHV-------------PSLTPINSVESSPNAEEIAQSCAIKSSFRPKLNISSLPFLGNKRNGNSCNLTDEQKAKLNCSTTLFDSKPIFEAESPDELALVDAAYSYNCRLLKRNPGSVIVDVP-GEGILEYEILQVLPFDSYRKRMSIILRHPHTNEITVYCKGADSSILPNLAPIEDDSEQKQIINRTQQQLHTYASKGLRVLLMAKRILSFSEYTDWLAMHQEYQLLHENRDSKLRESYSMLERKLSLLGATGIEDRLQEGVPETLVSLVASGIVVWVLTGDKQETAINIAFSAKLFNSDMEILKIMARSKKAAEDTIKCYLTEIEECSESNGSDRRSQPSSSTSELLRRTRVNRKKYSRALVVDGKSLTYILDKRSNLTKHFLKLTTFCNSVLCCRATPLQKAYIVKVVKEELKMRTLAIGDGANDVSMIQTADVGIGISGQEGMQAVMAADFALSKFKYLERFLLVHGHWSYDRLARMVLYFFYKNAAFVFLIFWYQLYCGFSGAVMIDQMYLMLYNLLFTSLPPLAIGVYDQDSPEDLLRQKPYLYRKGRLGKVYRSFSFWLTLADALYQSLAIFFICVAVYMDTAIDIWEFGTTVTTICMFVMSCHVAIEIKSWTIIHVASIVIS-IGAFYVYSILYNSLC--VNCFGLPSTYWVIQHAIISPTYWLSTLLSIVIALLPRLVFLVIKNTISPDDVTRALITYRRDNRRGEG 1418          

Query:   58 IPKKNGEEQCRKIYPSTSTNSNFEKY--KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDY----------AVKDDETDGQSDKVTMRSEF-----------------------GDTDDKKMNDDHG----------------------KKLLKNLIPMLH-GDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVIXXXXXXXXXXXXXXXXXAGEGVMNKAASISSFSAKNIFTKSGKVSMKNSDNTEIESKVHDVLFDRND-HSLELLNFKRNDSALPDFDDIHIRITDTNQKDYVQTPNKSRKVKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSDINTEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF--------GNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIF---QNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREE 3960
            +P+K      R + PS + + + +K    Y +N++RT KY+ ++F+P NLFEQ HRFAN+YF+F+  LNF+P +EAF  EV+ IP+V VLSVTAIKD  ED+RRF +D+ VN   C++YS  +K +V++ W + R GDFV+L  NE IPAD++LL+S+D  G+C+IET+NLDGE+NLKQR+VV  +   ++ F PE   +S IE ENPN ++ +F G I   S  + + L  +NLLLR CT+RNTE VIGIVVYAG ETKAM+NN+  R+KRS LER++N D++WCV LLI++CL  ++G+ +W         ++  K P        +PA+ AF  FWT +I  Q LIP+ LYV+ E VK+ Q++ I  DL++Y+ E +  ++ RA NI EDLGQIQYVF DKTGTLTEN+M F+R  I G +Y            ++D     S  VT++S                          +++++     H                       KKL     P+LH  D   K      +  + DFFL + ICNT VVS     +H + + +      +  K        +M +  S S F+     TKS   S  +             LF R    SL       N    P+             + Y +T   S KV+       GD ++AD +S + +    + +++    +E           + E D      DSF  D       S+ +LL  YE+ESPDE ALV  A  +   L  R P  + +  P     +   +L VLPFDSNRKRMS++V+ P T  ++++ KGADS +            ++++    +E T+ ++DAYAR GLR L + ++V+ +D +  W KR   AE  + N E+ LL     +E+++ LLG +GI D LQ+ V +TIE+L+RAGI VW+LTGDK+ETAINIA + KL   + +L+  +  +KE    L+ E +  ++      I  I              L++DG TL +A++D+++  FL L+ +C +V+C R+TP+QK+++VQLV++ L++ TLA+GDGANDVSMIQ+ADVG+GI G EGMQAVM+SDFA+ +F +L++LLLVHG WCY++LA   LY FYK+ +Y+ L+FW+QF   FS S+MI+    +LFN+  T +PP++YGV D+D  AD L+ +PELYR   + K Y P  FW+ ILDA +QS + + I Y     SD+G   FG  I   AL   L+H  IE+   TW H L +F+S   ++  F ++++  C  +VC    P + +    + +   LF+++C VT + A+ PR+   ++ NS++P+ L     R+E
Sbjct:  237 LPRK------RTVGPSFTDDEDLKKALKSYRSNKIRTTKYSFLSFLPKNLFEQLHRFANVYFIFLAALNFVPAVEAFQPEVSLIPIVLVLSVTAIKDVFEDFRRFHSDRLVNRQLCVVYSSLQKDYVDRCWKNVRVGDFVRLSCNEIIPADMLLLYSSDPRGVCYIETANLDGETNLKQRQVVSDLPLQDSEFSPENF-HSRIECENPNNDLSRFRGFIE-HSSGVRVGLHSSNLLLRSCTIRNTETVIGIVVYAGHETKAMMNNSGPRYKRSLLERRLNMDILWCVFLLIVMCLIAAVGHGLW---------LKDLKDPIFQVDGETSPALAAFYVFWTMIIVLQVLIPISLYVSIEIVKLGQIYFIHNDLDLYNEEQDSRIQCRALNITEDLGQIQYVFSDKTGTLTENKMVFRRCSIFGVEYPHEENARRLEVYEEDPNKAASRTVTLKSACSRKSLTCRSLSCNRSSVSLHTLTAESEEEDQLSSHPQAKTGAFCSPMAKDVVPDPALEKKLNSLRSPLLHLSDGLFKTTSNLELTYITDFFLALTICNTVVVSSPGQPRHVMREARTPLKSLEEIK--------LMFQRLSFSPFTTPQ--TKSSPRSFTSR------------LFTRGKTGSLTFPTPTNNIGERPN----------PGPESYEET--SSLKVELDASAGRGDLVWADPDSKEALRDAQISSDRFKESVE-----------DQEDD------DSFGED-------SEDELL--YEAESPDEAALVHAARAYHCTLRARSPENLLVELP-GIGSLPVRLLHVLPFDSNRKRMSVVVRHPLTGEVVVYTKGADSVIMDLAERPKGAEHAQELYSHIREQTQRHLDAYAREGLRTLCIAKKVLEEDEYDVWMKRQLLAESSIENREELLLESAQRLETNLTLLGSTGIVDRLQEEVPETIEALQRAGIKVWVLTGDKQETAINIANACKLLRSSDQLLTANCDNKEACAALLNELIVEVQCGEEGVIERIEDPSPG---SSGFILAIDGRTLDWALQDDLRSSFLELSRKCKAVLCCRSTPLQKSKVVQLVRDQLKVMTLAVGDGANDVSMIQVADVGIGISGQEGMQAVMSSDFAIPRFYHLRKLLLVHGHWCYHRLANMILYFFYKNVMYVNLLFWYQFFCGFSGSVMINSWVLILFNLLFTSVPPLVYGVLDQDTAADALLEHPELYRAARSSKVYVPSIFWITILDAFYQSCICFFIPYFALAGSDVGSLSFGSPINTSALFIILLHQVIESHTLTWIHALVLFLS-AASYFAFVLLFSTFC--IVCS--HPTNLLGVEPRQLSTPLFYIICAVTTVTALIPRILFRSVFNSVHPSSLLTKDQRQE 1523          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNH 390
            KY  N + T +Y+ +TFIP+NLF QFHRFAN+YF+F+ +LN++P +EAF KE+  IP++ VL+V  IKDA+EDYRR+ +D++VN+
Sbjct:   63 KYPGNAICTTQYSLLTFIPMNLFLQFHRFANLYFLFLALLNWVPVVEAFEKEITMIPLLVVLAVIGIKDALEDYRRYLSDKKVNN 147          

Query:   61 PKKNGEEQCRKIYPSTSTNSNFEKYKYAN-----NEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREV--VMMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVIXXXXXXXXXXXXXXXXXAGEGVMNKAASISSFSAKNIFTKSGKVSMKNSDNTEIESKVHDVLFDRNDHSLELLNFKRNDSALPDFDDIHIRITDTNQKDYVQTPNKSRKVKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSDINTE-----GDRNNSGIDSFKNDQDNK--CPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFS--KDISEIDQ--ENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQ---GKTRPLIRK--------DLALSVDGSTLTFAMEDE--IKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVC-GSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLGKGSNLYFDYEPELVDVR 4020
            P+   EE+ R + P+ +      + ++ N     N+VRT KY  ++F+P NL EQFHR AN+YF+FI++LN+ P I AFGKE+A IPV+FVL VTA+KD  ED RR  +D+RVN+S C IY     ++ +  W   R GD + L  NE +PADI+LL ++  +G+C+I+T +LDGE+NLKQREV    ++    F+P     S IEV+ P  +IY+F+G +   S +  + +   NLLLR C L+NT+ V GIVVYAG ETKAMLNN   R+KRS LERQ+N+DV WCVL+L+ILC+  ++G  +W + ++ Q   E +K   S      + + +AFLAFWT +I  Q +IPL LYVT E  K+ QV+HI  ++++YD E +K +E RA NI E+LGQ+QY+F DKTGTLTENRM F+R  I G DY   + E +G+  K +  +      + K+ +D   +L +            ++   +R   +++F LL+ +CNT V S      HP                       +MN +  I + S  N+F  SG   + + D T+ + ++H      ND   E L   R+ +  P  +                T N S +   V              S+  IN  +   N + +    +  +     +N       G++ N    +  ++Q  K  C  +  D    +E+ESPDE+ALV  A  +  +LL+R P  V +  P  E  + Y +LQVLPFDS RKRMSII++ P T+ I ++CKGADS++  N +  +D SE  Q    T+  +  YA  GLR+L+M +R++S   +++W   ++E +    N + +L    S +E  + LLG +GIED LQ+GV +T+ SL  +GI VW+LTGDK+ETAINIA+SAKLF+ +  ++++ A SK+   D IK +L  I+    +   + R      T  L+R+          AL VDG +LT+ ++    +   FL L   C SV+C R TP+QKA IV++VKE L+M+TLAIGDGANDVSMIQ ADVG+GI G EGMQAVMA+DFA++KFKYL+R LLVHG W Y++LAR  LY FYK+  ++ L+FW+Q    FS ++MID +  +L+N+  T LPP+  GV+D+D   D L + P LYR G   K Y+ + FW+ + DA++QS  I+ IC   +M + I IWEFG  +T   +     H+ IE + WT  H   I IS I A+ V++++Y  +C  V C G    Y  I   +    +WL  +++ + A+ PRL    I+N++ P+ + + LI   +  +        EP++V ++
Sbjct:  164 PRSEQEERYRIVVPNHTVPPKTPRKEHPNGNRPNNKVRTTKYTLLSFLPRNLLEQFHRVANLYFIFIVLLNWFPAINAFGKEIAMIPVLFVLGVTAVKDLFEDRRRHASDKRVNNSTCRIYQSEAARYKKVLWKELRVGDLIHLSNNEVVPADILLLRTSAPNGVCYIDTGHLDGETNLKQREVPRTFLKKQEIFEPSKF-RSHIEVDAPTTKIYRFHGAMLHPSGAREV-VGTENLLLRECLLKNTDYVEGIVVYAGHETKAMLNNGGPRYKRSALERQMNQDVFWCVLVLVILCVIGAVGCKLW-LQAYNQ-IKEPFKLEAS------SESTEAFLAFWTYIIILQIMIPLSLYVTLEMCKIIQVYHIHHNVDLYDTETDKRVECRALNITEELGQVQYIFSDKTGTLTENRMIFRRCTIAGVDYNHHNLENEGRGAKAS--AALSVIINPKLKEDLDSQLSEQ-------STIAQQRHAAR---IQEFLLLLAVCNTVVCS-----HHPHC--------------------DLMNASGVIEAVS--NVFATSGSARLNSIDCTDRDGQMHST----ND-KYERLKESRSVTPSPPLNS--------------HTHNDSLRATHV-------------PSLTPINSVESSPNAEEIAQSCAIKSSFRPKLNISSLPFLGNKRNGNSCNLTDEQKAKLNCSTTLFDSKPIFEAESPDELALVDAAYSYNCRLLKRNPGSVIVDVP-GEGILEYEILQVLPFDSYRKRMSIILRHPHTNEITVYCKGADSSILPNLAPIEDDSEQKQIINRTQQQLHTYASKGLRVLLMAKRILSFSEYTDWLAMHQEYQLLHENRDSKLRESYSMLERKLSLLGATGIEDRLQEGVPETLVSLVASGIVVWVLTGDKQETAINIAFSAKLFNSDMEILKIMARSKKAAEDTIKCYLTEIEECSESNGSDRRSQPSSSTSELLRRTRVNRKKYSRALVVDGKSLTYILDKRSNLTKHFLKLTTFCNSVLCCRATPLQKAYIVKVVKEELKMRTLAIGDGANDVSMIQTADVGIGISGQEGMQAVMAADFALSKFKYLERFLLVHGHWSYDRLARMVLYFFYKNAAFVFLIFWYQLYCGFSGAVMIDQMYLMLYNLLFTSLPPLAIGVYDQDSPEDLLRQKPYLYRKGRLGKVYRSFSFWLTLADALYQSLAIFFICVAVYMDTAIDIWEFGTTVTTICMFVMSCHVAIEIKSWTIIHVASIVIS-IGAFYVYSILYNSLC--VNCFGLPSTYWVIQHAIISPTYWLSTLLSIVIALLPRLVFLVIKNTISPDDVTRALITYRRDNR-------REPQIVGIQ 1423          

Query:  142 ANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVIXXXXXXXXXXXXXXXXXAGEGVMNKAASISSFSAKNIFTKSGKVSMKNSDNTEIESKVHDVLFDRNDHSLELLNFKRNDSALPDFDDIHIRITDTNQKDYVQTPNKSRK-----------VKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSD---------INTEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNF----SKDISEIDQEN----TKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKT-RPL------IRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            A+N ++T KY A++F+P NLFEQFHR AN+YFVFI +LNF+P + AF  E+A  PV+F+L+VTA+KD  EDY R+++DQ +NH +CL+Y  ++K++  + W   + GDFV+L  NE IPADI+LL S+D  G+CHIET+NLDGE+NLKQR+VV   +E ++ F P   + S IE E PN ++ +F G I  ++      L K+NLLLRGCT+RNTEEV GIV+YAG ETKA+LNNN  R+KRSKLERQ+N DV+WCVL+LI++CL  ++G+ IW V  +       +  P      + +PA+ A   F T +I +Q LIP+ LYV+ E VK+ QVF I +D ++YD E +  L+ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  + G +Y+      D  + ++ M  E  D++D    D+   K          G +  + + +S  ++VK            VV  N++ K            ++   R+      +++K  + SS   K+I      ++  N   + +E      +    DH L  L+       L D  D  I +T  N    V +PN+ R+           VK++ DF         T   +N + + L T+K ++    S I+ T ++         +      NN+G  + +          + +L   YE+ESPDE ALV  A  +   L+ R P+ V+I  P   R +T+ +L +L FDS RKRMS++V+ P TD I ++ KGADSA+        S D  +  Q+     T+++++ YA  GLR L + ++V+SK+ ++ W K + EAE  + N E+ L    + +E+D+ LLG +GIED LQDGV +TI +LR+AG+ +W+LTGDK+ETAINIAY+ KL   ++  I L+A S E    L+++ L  I+S +  E        T  PL      +  +L L VDG TL +A++  ++  FL LA++C SV+C R+TPIQK  +V+LV++ ++  TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ KF++L++LLLVHG WCY++LA   LY FYK+ +++ L+FW+QF   FS + MID    + FN+  + LP +I GV DKD+ +D L+  P LY++G + + Y+P  FW+N++DA++QS V + I Y T+  SD+ I+ +G  +T  AL T ++HL IET+ WTW H      S  L + V  + Y   C      S +PY  + + M   +F+L C++TP  A+ PR    T + +L+P  L  G
Sbjct:  153 ADNRLKTTKYTALSFLPKNLFEQFHRLANVYFVFIALLNFMPTVNAFQPELALAPVLFILAVTAVKDLWEDYSRYRSDQEINHMECLVYCRSEKKYTTRFWKEIQVGDFVQLRCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKQRQVVKGFLELDSEFDPLKFT-SIIECEEPNNDLSRFRGFIVHRNGKKA-ALYKDNLLLRGCTIRNTEEVSGIVIYAGHETKALLNNNGPRYKRSKLERQMNVDVLWCVLILIMMCLFSAVGHGIW-VWQYDDKRKPVFDVPGPDGNYL-SPAVAAVYLFLTMIIVFQVLIPISLYVSIEIVKVCQVFFIHQDKDLYDEETDFQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGIEYS-----HDANARRIAMYQE-ADSED----DETAPK----------GGVLSQRDSISSHQSVK------------VVHRNQSTK----------SHRRTGSRVEAKRASILSKHTAFSSPMEKDITPDPNLLAKVNECASYLE------IMRSQDHPLSQLS-----PELSDIFDFFIALTICNTV-VVTSPNQPRQKVRIRYELKSPVKTIEDFIRRLTPSRLTSGSNNSSSSSLATSKSTLRAGSSIISSTSAESTLQKVEEKLANSSQMNNNGYSAQQAKWTPGDEPGEGEL--RYEAESPDEAALVYAARAYDCALVGRLPDQVSIELPHLGR-LTFELLHILGFDSIRKRMSVVVRHPLTDEINVYTKGADSAIMDLLLPCSSDDPRDKHQKKIRSKTQNFLNLYAADGLRTLCIAKKVLSKEGYACWLKSHIEAESSIDNREELLFQSATRLETDLHLLGATGIEDRLQDGVPETIANLRKAGLKIWVLTGDKQETAINIAYACKLLDHDEEFITLNADSPEMCATLLEQHLHCIQSKFSVENSTQNTAPTFLPLYTPSSSVNPNLGLVVDGRTLAYALDKALEDKFLLLAQRCRSVLCCRSTPIQKGMVVKLVRDKIKTMTLAIGDGANDVSMIQVADVGVGISGPEGMQAVMASDFAIPKFRHLEKLLLVHGHWCYSRLANMVLYFFYKNAMFVSLLFWYQFYCGFSGASMIDQWYLIFFNLLFSSLPQLICGVLDKDVPSDILISVPHLYKSGQDMEEYQPHMFWMNMIDALYQSLVCFFIPYFTYYDSDVDIFSWGTPVTTVALFTIILHLAIETKTWTWLHWSSCAFSVGLFFTV-ALSYNATCPTCYPPS-NPYWIMEKLMGDPMFYLACLLTPAVALLPRFLYRTFQGTLFPTELQLG 1394          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF---GNFSKD-ISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKE----KTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSD-DPYDFIFQNMQRWLFWLLCVVTPLAAIFPR 3891
            YE+ESPDE ALV+ A  +G  LL R P  + +  P +  P++  +L +LPF S RKRMS++V+ P T  ++++ KGAD+ +    G  + D  S    E T+ ++D YAR GLR L + +R + +  +  W KR+  AE  + N E+ LL     +E+++ LLG +GI D LQ+ V +TIE+L+RAGI VW+LTGDK+ETA+NIA + KL     +L+  +  SKE    + ++L ++   +I+   P+      + +          L +DG TL FA+E++++  FL +   C SV+C R+TP+QK+++V+LV ++L + +LAIGDGANDVSMIQ+ADVGVGI G EGMQAVM+SDFA+++FK+L++LLLVHG WCY +LA   LY FYK+ +Y+ L+FWFQF   +S S M +    + FN+  T +PP++YGV DKD+ A+TL+  P+LY+ G N ++Y P  FW+ +LDA +QS V + I Y  +  SDIG++ FG  I   AL+  L+H  IE+R  TW H + +F+     +  F +++++ C  V C    +PY    + M    ++ +C +T + A+ PR
Sbjct:  692 YEAESPDEAALVQAARAYGCTLLGRSPEQLLVALPGTG-PLSVPLLHLLPFHSARKRMSVVVRHPLTGQVVVYTKGADNVIMELAGTSAADGCSREIMEKTQQHLDNYAREGLRTLCVAKRALDEAEYEAWLKRHAFAETSIENREQLLLESAQRLETNLTLLGATGIVDRLQEEVPETIEALQRAGIKVWVLTGDKQETAVNIACACKLLRPTDQLLTANCDSKEACEARLYELQRDISTSIERGLPDRSAVTSEDQA---AVSGFTLVIDGRTLDFALEEDLQKLFLDVTGNCRSVICCRSTPLQKSQVVRLVGDSLGVMSLAIGDGANDVSMIQVADVGVGISGQEGMQAVMSSDFAISRFKHLRKLLLVHGHWCYTRLANMILYFFYKNVMYVNLLFWFQFFCGYSGSTMTNSWVLIFFNLLFTSVPPLLYGVLDKDVSANTLLSLPQLYKAGQNSQAYLPCTFWLTMLDAFYQSLVCFFIPYFAYADSDIGLFSFGSPINGSALLIILLHQVIESRTLTWIHAV-VFLGSAAFYYTFVLVFSLTC--VTCNPPTNPYGVETRAMSHPSYYFVCGLTTILALLPR 1273          

Query:   88 RKIYPSTSTNSNFE--KYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDD--------------------------------------------ETDGQSDKVTMRSEF-----GDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPV 1578
            R + P    N   E  + KY+ N++RT KY  ++FIP NLFEQ HRFAN+YF+F+  LNF+P + AF  E++ IP++ V+SVTA+KD  ED RR K+D++VN+  C  Y   ++++VE++W+    GD V+L  NE IPAD+VLLHS+D +G+CHIET+NLDGE+NLKQR+VV  + +  + F PE  S S IE ENPN ++ +F G +   ++ + + L   NLLLR C +RNTE VIGIVVYAG ETKAM NN+  R+KRSKLER++N DV+W V++L+++CL+ +IG+ +W + SF    +  +  PD       +PA+  F  FWT +I  Q LIP+ LYV+ E VK+ Q++ I+ DL++Y+ + + G++ RA NI EDLGQIQY+F DKTGTLTENRM F+R  + G +Y   ++                                            E+D  S   T+R        G  +   + D   ++ L+ L   L   I    EE+S   ++ DFFL + +CNT VVS     +H V
Sbjct:   22 RVVVPEWVYNEEAEGLQRKYSGNKIRTTKYTFLSFIPKNLFEQLHRFANVYFIFLAALNFVPIVNAFQPEISIIPIILVMSVTAVKDLWEDQRRRKSDRQVNNLLCDAYDRKQRRYVERRWAEVCVGDVVRLCCNEIIPADMVLLHSSDTNGVCHIETANLDGETNLKQRQVVRNLPQQGSEFTPENFS-SRIECENPNDDLRRFRGYMEHPNK-VKVGLHSENLLLRSCIVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNVDVLWSVVILLLMCLTAAIGHGLW-LNSFEDHPV--FLIPDDT-----HPALAGFYMFWTMIIVLQVLIPVSLYVSIEIVKLGQIYFIQNDLDLYNPKLDSGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVSGTEYPHHENARAMEQFEEQCRGQVENTLTLRSRSSRKSLSCNRSSVSLNTLAAESDIHSPHDTLRRHAAGAFSGTMECAVVPDVQLQEKLRALSAPLCPPIRHDAEELS---HILDFFLALTVCNTVVVSSPSQPRHVV 558          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF---GNFSKD-ISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKE----KTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETR 3690
            YE+ESPDE ALV+ A  +G  LL R P  + +  P +  P++  +L +LPF S RKRMS++V+ P T  ++++ KGAD+ +    G  + D  S    E T+ ++D YAR GLR L + +R + +  +  W KR+  AE  + N E+ LL     +E+++ LLG +GI D LQ+ V +TIE+L+RAGI VW+LTGDK+ETA+NIA + KL     +L+  +  SKE    + ++L ++   +I+   P+      + +          L +DG TL FA+E++++  FL +   C SV+C R+TP+QK+++V+LV ++L + +LAIGDGANDVSMIQ+ADVGVGI G EGMQAVM+SDFA+++FK+L++LLLVHG WCY +LA   LY FYK+ +Y+ L+FWFQF   +S S M +    + FN+  T +PP++YGV DKD+ A+TL+  P+LY+ G N ++Y P  FW+ +LDA +QS V + I Y  +  SDIG++ FG  I   AL+  L+H  IE+R
Sbjct:  722 YEAESPDEAALVQAARAYGCTLLGRSPEQLLVALPGTG-PLSVPLLHLLPFHSARKRMSVVVRHPLTGQVVVYTKGADNVIMELAGTSAADGCSREIMEKTQQHLDNYAREGLRTLCVAKRALDEAEYEAWLKRHAFAETSIENREQLLLESAQRLETNLTLLGATGIVDRLQEEVPETIEALQRAGIKVWVLTGDKQETAVNIACACKLLRPTDQLLTANCDSKEACEARLYELQRDISTSIERGLPDRSAVTSEDQA---AVSGFTLVIDGRTLDFALEEDLQKLFLDVTGNCRSVICCRSTPLQKSQVVRLVGDSLGVMSLAIGDGANDVSMIQVADVGVGISGQEGMQAVMSSDFAISRFKHLRKLLLVHGHWCYTRLANMILYFFYKNVMYVNLLFWFQFFCGYSGSTMTNSWVLIFFNLLFTSVPPLLYGVLDKDVSANTLLSLPQLYKAGQNSQAYLPCTFWLTMLDAFYQSLVCFFIPYFAYADSDIGLFSFGSPINGSALLIILLHQVIESR 1238          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDD--------------------------------------------ETDGQSDKVTMRSEF-----GDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPV 1578
            Y  N +RT KY  ++FIP+NLF+QFHR AN+YF+F+++LN++P +EAF KE+  IP+  VL V A KDA+EDYRR++ DQR+N++   +YS  ++++VE++W+    GD V+L  NE IPAD+VLLHS+D +G+CHIET+NLDGE+NLKQR+VV  + +  + F PE  S S IE ENPN ++ +F G +   ++ + + L   NLLLR C +RNTE VIGIVVYAG ETKAM NN+  R+KRSKLER++N DV+W V++L+++CL+ +IG+ +W + SF    +  +  PD       +PA+  F  FWT +I  Q LIP+ LYV+ E VK+ Q++ I+ DL++Y+ + + G++ RA NI EDLGQIQY+F DKTGTLTENRM F+R  + G +Y   ++                                            E+D  S   T+R        G  +   + D   ++ L+ L   L   I    EE+S   ++ DFFL + +CNT VVS     +H V
Sbjct:   71 YQGNGIRTTKYTLLSFIPMNLFQQFHRAANLYFLFLVLLNWVPVVEAFQKEITMIPLAVVLIVIAFKDAMEDYRRYRYDQRINNTLTHVYSGKQRRYVERRWAEVCVGDVVRLCCNEIIPADMVLLHSSDTNGVCHIETANLDGETNLKQRQVVRNLPQQGSEFTPENFS-SRIECENPNDDLRRFRGYMEHPNK-VKVGLHSENLLLRSCIVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNVDVLWSVVILLLMCLTAAIGHGLW-LNSFEDHPV--FLIPDDT-----HPALAGFYMFWTMIIVLQVLIPVSLYVSIEIVKLGQIYFIQNDLDLYNPKLDSGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVSGTEYPHHENARAMEQFEEQCRGQVENTLTLRSRSSRKSLSCNRSSVSLNTLAAESDIHSPHDTLRRHAAGAFSGTMECAVVPDVQLQEKLRALSAPLCPPIRHDAEELS---HILDFFLALTVCNTVVVSSPSQPRHVV 588          

Query: 2104 DQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNF---SKDISEIDQEN-----TKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNY-------------------------PNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            DQD     ++ +L   YE+ESPDE ALV  A  +   L+ R P+ VT+  P   + +T+ +L  L FDS RKRMS++V+ P T+ I ++ KGADS +       ++D S+  ++      T++Y++ YA  GLR L + ++V+SK+ ++ W +R+ EAE  +   E+ L      +E+D+ LLG +GIED LQDGV +TI +LRR             ETAINIAY+ KL    + +I L+A S+E    L+ E L  I++ +                         P        G     +   L L +DG TL +A++  ++  FL +A  C SV+C R+TP+QK+ +V+LV+  L++ TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F+YL++LLLVHG WCY++LA   LY FYK+ +++ L+FW+QF   FS S MID    + FN+  +  P +I G  DKD+ A+TL   P+LY +G N + YKP+ FW+N++DA +QS V + I Y  ++ S           +   L     HLGIET+ WTW +   I  S  L + V  + Y   C      S +PY  I + +   LF+LLC+VTP+AA+ PR      + SL+P+ +  G
Sbjct:  675 DQDKASAPAECEL--RYEAESPDEAALVYAARAYKCSLVGRLPDQVTVELPHLGK-LTFELLHTLGFDSTRKRMSVVVRHPLTEQITVYTKGADSVIMDLIRPPTRDDSKGKRQRKVLYKTQNYLNLYAADGLRTLCIAKKVLSKEEYAGWLRRHLEAEAAIQGREELLFESALRLETDLHLLGATGIEDRLQDGVPETIAALRR-------------ETAINIAYACKLLDPEEEIITLNADSQEACAVLLDESLHYIQAKFFCSSSADPHAARAFQQDYTAVHFPAPPACSPASSGAPSTFLVHRLGLVIDGRTLAYALDKSLEDKFLAVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFQYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMIDQWYLIFFNLMFSAFPQLITGTLDKDVSAETLQELPQLYMSGQNSEEYKPYMFWMNMIDAFYQSLVCFFIPYFMWICSPGAPPSLHSPSSPFCL-----HLGIETKTWTWMNWASIAFSIALFFTV-ALCYNSSCPTCYSPS-NPYWTIQRLLGDPLFYLLCIVTPIAALLPRYFYRICQGSLFPSPMLVG 1298          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPT--------VIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLK 1434
            YANN+++T KY  ++FIP NLFEQFHRFAN+YFVFI +LNF+P + AF  E+A  PVVF+LSVTAIKD  EDYRR ++D+ +NH  CL+YS +++++VEQ W   R GDF++L  NE +PAD++LL S+D   +CHIET+ LDGE+NLKQR+VV   ++ +  F P +  NS IE E PN ++ +F G I  ++      L K+NLLLRGCT+RNTEE +GIV+YAG ETKAMLNNN  R+KRSKLERQ+N DV WCV++L+++CL  +IG+ +W            Y++ D  P            +P + A   F T +I +Q LIP+ L+V+ E VK+ QVF I +D+E+YD E +  L+ RA NI EDLGQ+QY+F DKTGTLTEN+M F+R  + G +Y+      D  + ++ M  E    +++ ++  HG  L +
Sbjct:   54 YANNKIKTTKYTLLSFIPKNLFEQFHRFANVYFVFIALLNFVPVVNAFQPELALAPVVFILSVTAIKDLWEDYRRHRSDKEINHMDCLVYSRSERRYVEQYWKEIRVGDFIRLRCNEILPADVLLLSSSDPDRLCHIETATLDGETNLKQRQVVRSFIDLDTEFDP-LKYNSVIECEKPNNDLNRFRGYITHRNGRRD-GLYKDNLLLRGCTIRNTEEAVGIVIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFSAIGHGLWM-----------YQYGDKRPVFDVLSPEGTDLSPVVSAIYLFLTMIIVFQVLIPISLFVSIEIVKICQVFFIHQDMELYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYS-----HDANARRIAMYQEMDSEEEECLS--HGGTLPR 475          

Query: 2068 DRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDT-IYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPN 3930
            D N  G  S  N +          L   YE+ESPDE ALV  A  +G+ LL+R P+ VT+  P   + + + VL VL FD  R+RMSIIV+ P+T  IIM+ KGADS +          ++   T+  +D YAR GLR L   ++V+++  +S W  R +EA   +   ++ L+   +++E+++ LL  +GIED LQ+ V +TI +LR AGI VW+LTGDK ETA+NIAYS  L      +   +  SK       +EF                           + L +DG TL+  ++D+++  F+ L   C SV+C R TP+QK+ +V L++  L++ TLAI DGANDV+MIQ ADVGVGI G EGMQAVMASDF++++FK+LK+LLLVHG WC  +LA   +Y FYK+   Y+ L+FW+Q    F+ + MID    + FN+  T  PPI++G+ D+++ A  L++ P+LY+ G     Y+   FW+ ILDA +QS + + I Y  +  SD+ I+  G  +   +L T ++HL IE + WT  H + I +  +L + + ++ ++ +C  + C    DPY  + Q M   +F+L+C++T + A+ P   ++ +R +L P+
Sbjct:  617 DENAPGHRSNVNRRPRTGSSPAAPLEVCYEAESPDEAALVHAAKAYGFTLLERTPDHVTVRLPHG-KELKFKVLDVLNFDPVRRRMSIIVRHPRTREIIMYTKGADSGI----------MEAAETQGDLDMYARDGLRTLCFAKKVVNEQTYSAWSIRRQEALAAISRKKELLMDTAADMENNLTLLA-TGIEDRLQENVPETIRALREAGIQVWVLTGDKLETAVNIAYSCMLLDHRDLVFTFNTESK-------REF--------------------------SIGLVIDGRTLSLLLDDDLQTQFVELCSHCRSVLCCRATPLQKSRVVTLMRHRLKVMTLAI-DGANDVNMIQAADVGVGISGQEGMQAVMASDFSISRFKHLKKLLLVHGHWCSTRLANMIVYFFYKNVQAYVNLLFWYQLFCGFTGTAMIDYWFMIFFNLLFTSAPPIMFGIMDREISAFMLLQLPQLYKRGQQTGGYRRSTFWIGILDAFYQSFICFFIPYWAYEGSDVDIFTLGIPMNTVSLFTIILHLAIEIKSWTVVHWV-IMVGSVLVYFIVSLAFSALC--ISCNPPSDPYWLMQQQMADPIFYLICILTTVVALLPYF-LHALRGTLMPS 1189          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDY---------AVKDDETDGQSDKVTMRSEF---------------------GDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVK-----DFFLLMGICNTTVVSLNKNEKHPV 1578
            YA N ++T KY    FIP NL EQF R AN YF+ I ILNF+P + AF  +VA IP+  +LS+TAIKDA ED+RR+++D+++N   CLIYS +++ F+E++W   + GDFV++ +NE IPADI+LLH++D +G+CH+ET+NLDGE+NLKQR VV    + N+TF+P+   NS +  E PN  +  F+G   F+  +        +LLLRGCT+RNT +  GIVVYA  ETK+MLNNN  R KRSKLER++N +V +CVLLLI +CL  ++ +VIW + SF+   I  Y  P+S  T   + A+     F+T +I  Q +IP+ LY++ E VKM QV+ I +D+++YD E +  ++ RA NI EDLGQIQY+F DKTGTLTEN+M F+R  I G +Y         A+   ETD   + +  ++                       G++   +     G          +  ++   E  +  M+N +     DFFL M ICNT VVS +   +  V
Sbjct:   41 YAGNAIKTTKYTLWNFIPKNLIEQFRRVANAYFLSIAILNFVPSVNAFQPQVALIPICVILSLTAIKDAWEDFRRYQSDRKLNRRPCLIYSRSQQSFMERRWKDVKVGDFVRVLSNEIIPADILLLHTSDPNGVCHMETANLDGETNLKQRRVVPGFCDTNSTFEPQNF-NSIVVCEKPNDNLNHFSG---FEKGNKKTGFGIESLLLRGCTVRNTADASGIVVYA-HETKSMLNNNRPRNKRSKLERKMNIEVFFCVLLLIFMCLIGAV-HVIW-LESFST--IPMYFIPNSDGTYT-SSALSGVNMFFTMIILLQVIIPISLYLSIELVKMGQVYFITQDVDLYDEERDIRMQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGTEYPHSENATRLALLAGETDADEEVIYQQNRRPPLFSLEEAQDGPARASARLPGNSSLHRSRVTAGASSCMAFSSPMETEVVPDETLLHLMENEEDKSYLDFFLAMAICNTVVVSTDTARRQGV 547          

Query: 2149 SYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDI-------GIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSD--DPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLL 3936
            +Y++ SPDE ALV+ A   G+    R P+ V + +   E    Y +L VL F S RKRMS+I++ P +  I ++CKGAD+ ++   + +    D   T  +++ +A  GLR L      IS+  + +W + +  A   L N   +L      IE ++ LLG + IED LQD V +TIE+L +A I +WILTGDK+ETAINI +S KL ++N  L+ ++  + + T + +    G +      E               D AL +DG TL +A+    +  FL LA  C +V+C R +P+QK+E+V++VK+ +++ TLAIGDGANDV MIQ A VGVGI GNEG+QA  +SD+++ +FKYLK LLLVHG+W YN++A+  LY FYK+ +  ++  WF F N FS  ++ +     L+N+  T LPP+  G++++    + +++ PELY+   N   +    FW + L+ ++ S +++      F    +            G ++    +IT  +  G+ET  WT F  + I+ S  L W+VF  IY+ +   +    D     D +F +    +FW+     P+ ++   +    I+ + +  L+
Sbjct:  312 TYQAASPDEGALVRAAQNLGFVFSARTPDSVIVESLGEEEK--YELLHVLEFTSARKRMSVIMRTP-SGKIRLYCKGADTVIYDRLADNSRYKDI--TLKHLEQFATEGLRTLCFAVADISESLYQQWLEVHHRACTSLQNRALKLEESYELIEKNLQLLGATAIEDKLQDRVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLTKNMGLLVINEETLDGTRETLSHHCGMLGDALHKE--------------NDFALIIDGKTLKYALTFGARQYFLDLALSCKAVICCRVSPLQKSEVVEMVKKQVKVITLAIGDGANDVGMIQTAHVGVGISGNEGLQAANSSDYSIAQFKYLKNLLLVHGAWNYNRVAKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLYNVIFTALPPLTLGIFERSCRKENMLKYPELYKTSQNAMGFNTKVFWAHCLNGLFHSVILFWFPLKAFQHDTVFGNGKTPDYLLLGNMVYTFVVITVCLKAGLETSSWTMFSHIAIWGSIGL-WVVFFGIYSSLWPLIPLAPDMSGEADMMFNSG---VFWMGLFFIPVTSLVFDVAYKVIKKACFKTLV 893          

Query:  535 GICHIETSNLDGESNLKQREVVMMENN-NTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQA--FLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTV 1545
            G+C+IETSNLDGE+NLK R+ + + +        M  +  +E E+PN+ +Y+F G I     S  + L  + +LLRG  LRNT+ V GIVVY G +TK M N+     K S +ER  N  ++     L+ + L CSIG  IW            Y++ +    +  N    A   L F T +I +  LIP+ L VT E +K  Q + I  D +M           R  N+ E+LGQ++Y+F DKTGTLT N M+FK+  + G  Y        G S      + F D             LL+NL           +        + DF  +M IC+T V
Sbjct:    6 GMCYIETSNLDGETNLKIRQGLQITSEIKDIDSLMRLSGRMECESPNRHLYEFVGNIRMDGHST-VPLGPDQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTRPPLKLSNVERITNFQILVLFGCLLAISLVCSIGQTIWK-----------YQYGNDAWYMDLNYGGAANFGLNFLTFIILFNNLIPISLLVTLEVIKFIQAYFINWDTDMIYEATNTPAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTVAGVAY--------GHSSHSMEEAGFND-----------PSLLENL-----------QSNHPTAPVIMDFMTMMAICHTAV 303          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF-------GNFSKDISEID-QENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIEL---SASSKEKTHDLIKEFL--GNIK----SNYPNEIME-------IRQGKTR-PLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGS-DDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            YE+ESPDE ALV  A  + + L+ + P+ V I  P   R +T+ +L V+ FDS RKRMS++V+ P TD ++++ KGAD+ +        GN  KD ++      T+  ++ YA  GLR L + +R ++ D ++ W K + EAE  +   E+ L      +E DM LLG +GIED LQDGV +TI +LR AG+ +W+LTGDK+ETAINIA+S KL   +  +I L   S S  +  H  +      G ++    +  P + +E       I  G+ R  ++     L +DG TL+FA+  +++ +FL L   C SV+C R+TP+QK+ +V+LV+E L++ TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVM+SD+AM +F++L +LLLVHG WCY++LA   LY FYK+  ++ L+FW+QF   FS S  ID    +LFN+    LPP++ GV DKD+ A+TL+  P LY+NG N  +Y+P  FWV ++DA++QS V + + Y+ +  SD+ I+ +G  IT  +L + L+HL IET+ WTW H   I +S +L + +F + Y  IC  + C +  +PY  +   M + LF+L+CVVTPL A+ PRL   T+  S +P+   +G
Sbjct:  678 YEAESPDEAALVYAARAYNFTLVSKSPDQVIIDVPHVGR-LTFDLLHVMAFDSTRKRMSVVVRHPLTDEMVVYTKGADNVIMDILKPCTGNSDKDKAKAKMHARTQADLNQYAMDGLRTLCIAKRELTDDEYATWAKSHLEAEAAIDCREEMLFESALRLERDMQLLGATGIEDRLQDGVPETIAALRDAGLQIWVLTGDKQETAINIAFSCKLLDASDEIITLNTESLSRGQHRHRTLCSLASTGGVRQAAEAVAPEQELERGGRGAVICDGRYRGTVVTTRRGLVIDGKTLSFALNKDLEENFLKLTRDCRSVLCCRSTPLQKSMVVKLVREKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMSSDYAMPRFRHLHKLLLVHGHWCYDRLANMVLYFFYKNAAFVTLLFWYQFFCGFSGSSQIDQWYLMLFNLLFCSLPPLVTGVLDKDVSAETLLARPHLYQNGQNSLAYRPILFWVTMMDALYQSMVCFFLPYLAYRGSDVDIFTWGTPITTVSLFSILLHLAIETKTWTWIHWGSIALSLLL-YFLFVLAYNAIC--INCAAPSNPYMIMEILMTQPLFYLVCVVTPLVALLPRLVYRTLEGSCFPSENLRG 1297          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQD--FIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYY-QALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDY----------AVKDDETDG--------------------------------------------QSDKVTMRSEFGDTDDKKMNDD-----HGKKLLKNL--IPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVS 1551
            +A+N ++T KY   +F+P NLFEQFHRFAN+YFVFI++LNF+P + AF   +A +PV F+L+VTA+KD  EDYRR+ +D+ +N++ CL+Y  A++ F+E+ W   R GDF+KL  NE IPAD++L+ S+D  G+CH+ET+NLDGE+NLK R++V    + +  F P M   S +E E PN ++ KF G     S    + L K+NLLLRGCT+RNTE V+GIVVY G ETKAMLNNN  R+KRSKLER +N D+IWCV++LI++CL  +I + +W +  + ++  F    K    I     +P +  F  FWT +I   Q LIP+ LYV+ E VK+ Q++ I +D E+YD E++  L+ RA NI EDLGQI+Y+F DKTGTLTEN+M F+R  + G +Y          A +D E+DG                                            Q   ++  + F    +K +  D       +  LKNL  +P  +G I I E+    + NV DFF+ + ICNT VVS
Sbjct:   47 FASNAIKTTKYTVWSFLPKNLFEQFHRFANVYFVFIVLLNFVPVVNAFQPGLAVLPVAFILAVTAVKDLWEDYRRYHSDREINNAPCLVYCRAQQGFIERCWKDVRVGDFLKLRCNEIIPADVLLMASSDPDGLCHLETANLDGETNLKLRQLVKGFADLDCDFDP-MKYTSIVECERPNNDLNKFKG-FMLHSNERKVGLSKDNLLLRGCTVRNTEYVVGIVVYGGHETKAMLNNNGPRYKRSKLERNMNMDIIWCVIILIVMCLFIAIAHGLW-MAGYEENPPFDVASKDGSHI-----SPVLSGFYMFWTMIIILQQVLIPISLYVSIEIVKIGQIYLIHQDEELYDPESDTPLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVAGKEYSHSNNAQRLAAYQDSESDGDEWARGDSLWRERHRRSLRRTPSAHSTRSAPGARSTPCLMGHRRQPSVLSKEAAFSSPMEKDVTPDPQLESRVRMYLKNLKSLPSKNGTIVIPED----VANVVDFFITLAICNTVVVS 571          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRL------------------IELSASSKEKTHDLIKEFLGN------IKSNYPNEIMEIRQGK-----TRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITF---MSSDIGI----WEFGQIITACALITCL-VHLGIETRFWTWFHGLGIFISFILAWLV 3750
            Y+++SPDE ALV  A   GY  L R    VTI    +ER   Y +L +L F+S+RKRMS+IV+ P+   + ++CKGAD+ +     KD  + ++E+T+  ++ +A   LR L +  + +S++ + +W K+Y++A   L + EK+   +  +IE+++ LLG + IED LQDGV + I  L  A I +W+LTGDK+ETA NI Y+  L +E+ ++                  I+  A   E+  D  K+FL        I     N I+   + K       P  RK      +         + I+  F+ LA  C +V+C R +P QKA +V++V ++ +  TLAIGDGANDV+MI+ A +GVGI G EGMQAV++SD++  +F++L+RLLLVHG W Y ++ +   Y FYK+  + L+ FWF F N FSA  + D     L+N+  + LP ++ G++D+D+      + PELY  G    ++    F   ++  I  S +I+ I Y  F   M SD G+    ++   ++TA +L   + + +G++T FWT+ +   IF S  L + +
Sbjct:  514 YQAQSPDEGALVTAARNFGYVFLDRTLESVTIVELGTER--VYELLNILDFNSDRKRMSVIVRSPE-GKLRLYCKGADTVILERLQKD--DPNRESTEKDLNTFAAESLRTLCLSYKDLSEEEYLDWSKKYEQASMSLTDREKKQGLVYEKIETNLKLLGATAIEDKLQDGVPEAIAKLAAAKIKIWVLTGDKQETAENIGYACHLLTEDMQICYGDEVSTMLSDVQECQTIKRDAKGNEEEVDFAKQFLKGKKNAIIITGGCLNGILTDNKQKRLDRLKLPRRRKPREQREEEKQREILKRERIEKRFVSLACACEAVICCRVSPRQKARVVRMVMKHKQAVTLAIGDGANDVNMIKTAHIGVGISGQEGMQAVLSSDYSFAQFRFLERLLLVHGRWSYLRMCKFLQYFFYKNFAFTLVHFWFSFFNGFSAQAVYDDWYITLYNMLYSALPVLVMGLFDQDVSDSKSFKFPELYETGQKNLNFNYKIFGRCLIQGIITSLIIFFIPYGAFLETMRSD-GLAPDDYQSFAVVTATSLTLIVNLQIGLDTAFWTYLNTFSIFGSIALYFAI 1077          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLS--NSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIP------TVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDD 1335
            +Y  N ++T KYN +TF+P+NL EQF R AN+YF+F+LIL  +P I +       +P+V VLS+TAIKDAV+D  R ++D+++N+ KC I       F E KW + + GD ++L  N+ +PAD++LL + + + +C++ET+ LDGESNLK ++ + + +NN    + L+  ++ I  E PN  + K+ GT+ +K +    +L  + LLLRGC +RNTE   G+V++AG +TK M N+ +T+FKR+++++Q+NK V     +L+++    +IGN IW V    Q F +Y       P      TV        FL FW  +I    ++P+ LYV+ E +++ Q F I  DL MY    +     R   + E+LGQI+Y+F DKTGTLT+N M FK+  I G  +   +D
Sbjct:   44 RYKGNYIKTAKYNIVTFLPMNLLEQFQRVANVYFLFLLILQAIPIISSLAWYTTFVPLVIVLSITAIKDAVDDISRHRSDKQINNRKCEIMQNG--SFKEDKWMNIQVGDLLRLKKNDFVPADMLLLSTTEPNSLCYLETAELDGESNLKFKQALTVTHNNLTDEKQLAEFDAIIMSEAPNNRLDKYLGTMQWKDKM--YSLDNDKLLLRGCRIRNTETCHGLVIFAGFDTKIMKNSGETKFKRTQIDKQMNKIVFMIFGMLLVMATGLAIGNTIWEVVH-GQGFGKYCSGITGDPAVPSPDTVSEWAVWTGFLNFWGYIILLNTVVPISLYVSVEVIRLGQSFFINWDLRMYFKVNDTPSNARTTTLNEELGQIEYIFTDKTGTLTQNIMTFKKCSISGMAFGGCED 446          

Query:  160 TQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLS-NSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTV 1545
            T KYNA+TF+P  L+EQF R AN++F+FI +L  +PE+   G+    +P++F+L V A+K+ +EDY+R +AD+ VN  K          +    W     GD +++   + +PAD+V+L S++   +C+IET+NLDGE+NLK R+ + +         +LS +  IE E PN+ +Y F G I  +     + L  + +LLRG  LRNT+ V G+VVY G +TK M N+     KRS ++R  N  ++  V+ L+++ L+ +IG+ IWT   +  D+  Y  F D+ P+            F T +I Y  LIP+ L VT E VK  Q F I  D EMY  E+      R  N+ E+LGQ++Y+F DKTGTLT N MEFK+A + G  Y   ++            SE G  D   + + H       +I                     +F ++M +C+T V
Sbjct:    2 TAKYNALTFLPRFLYEQFSRAANLFFLFIALLQQIPEVSPTGRYTTLMPLIFILVVAALKEIIEDYKRHRADREVNKKKT-TQVLQNGDWHTVSWEKVGVGDVLRITNGQNLPADLVMLSSSEPQAMCYIETANLDGETNLKIRQGLPLTAGLQTSDSLLSIDGRIECEAPNRHLYDFTGNIQLQGHGT-VPLGPDQILLRGAQLRNTQWVFGVVVYTGHDTKLMQNSTRAPLKRSNVDRVTNLQILLLVVTLLLMALASAIGSSIWTSAHWKGDW--YLGFRDNAPSNFG-------FNFLTFIILYNNLIPISLLVTLEVVKFIQAFFINWDSEMYHEESNTNAMARTSNLNEELGQVKYIFSDKTGTLTCNVMEFKKATVAGIAYGHNEEP-----------SEVGFQDPALLQNLHSNHPSAGVI--------------------YEFLVMMSVCHTAV 422          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMG 2475
            Y++ SPDE ALV+ A   G+    R PN V I     E+   + +L VL F S R+RMS+IV+ P +  + ++CKGAD+A++   + +   + +E+T  +++ +A  G
Sbjct:  432 YQASSPDEGALVRAARSLGFTFTVRTPNMVVIDALGQEQ--NFELLHVLEFTSVRRRMSVIVRTP-SGKLRLYCKGADNAIYERLANN--SLYKEDTLQHLELFASEG 534          

Query:  148 NEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSNSFIEV--ENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXX-XXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIP--TVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTV 1545
            N ++T KYN +TF+P+NLFEQF R AN YF+F+LIL  +P+I +       +P+V VL++TA+KDA E+Y R ++D +VN+ +  ++   K Q   +KW + R GD +K+  N+ + AD++LL S++   +C+IET+ LDGE+NLK R+ + + +      + L++   EV  E PN ++ +F GT++++  +   +L  + +LLRGC LRNTE   G+VV+AG +TK M N+  T+ KR+ ++R +N  V+W +   ++ +     +GN IW      +  I YY F   +P  + + +     FL FW+ +I    ++P+ LYV+ E +++   + I  D +MY  + +   EVR   + E+LGQI+Y+F DKTGTLT+N M F +  I+G  Y    D T     KV       + +++ +  D  + LL +   + +    ++   +     V +FF L+ +C+T +
Sbjct:    2 NRIKTSKYNVVTFLPVNLFEQFQRVANAYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDASEEYFRHRSDNQVNNRQSQVHINGKLQ--NEKWMNVRVGDIIKMENNQFVAADLLLLSSSEPHSLCYIETAELDGETNLKVRQALPVTSQIADDIDKLAHFDGEVICEPPNNKLDRFTGTLYWRGNT--YSLDNDKMLLRGCVLRNTEWCYGLVVFAGPDTKLMQNSGRTKLKRTSIDRLMNTLVLWWIFGFLVCMGSILGLGNTIW------ESAIGYY-FQPYLPWESAVDSAIFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYGKRDTPAEVRTTTLNEELGQIEYIFSDKTGTLTQNIMTFNKCSINGRVYGGAYDVT---GHKV-------EINERSVPVDFSRNLLADRRFLFYDQTMLEAIRLGEW-GVHEFFRLLALCHTVM 450          

Query: 2149 SYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQEN---TKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKT-----HDL----IKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSV-DGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDG--ANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSS----DIGIWEFGQIITACA---LITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLF-----WLLCVVTPLAAIFPRLTINTIRNSLYPNL 3933
            +Y+++SPDE ALV  A    +    R P  +T+   E   P TY +L +L F++ RKRMS+IV+  +   + ++CKGADS +F    + +   +Q+    T D++ A+A  GLR L +  R + +  F EW +R+ EA   L   E+ L ++  EIE +MMLLG + IED LQ+GV +TI  L  A I +W+LTGDK+       Y + L S  ++ + L   S   T     H +    ++   G   S+    + ++       +I  D A  V +G  L   +   +K DFL       S V  R T   ++E  + V +    Q + + DG  +++  +I+ A +GVGI G EGMQAV++SD++  +F++L+RLLLVHG W Y ++ +   Y FYK+  + L+ FWF F   FSA  + D     LFNI  T LP +  GV+D+D++    +  P+LY  G     +    F++ I   I+ S V++ + Y  F+ +      G+ +   +  A +   +I   + +G++T +WT  +   I+ S  + + +   +Y+     +      P  F F    R        WL+  +T +  I P      ++  L P L
Sbjct:  460 AYQAQSPDEGALVTAARNFDFVFRSRTPETITL--HELGEPRTYQLLAILDFNNFRKRMSVIVRNAE-GRLKLYCKGADSVIF----ERLHPCNQQLVNITADHLSAFAGEGLRTLCLAYRDLDEASFEEWQERHHEANTSLQGREELLAAVYDEIEQNMMLLGATAIEDKLQEGVPETIAKLALANIKIWVLTGDKQAATRAAFYRSSLISIVRKNVHLILMSSLLTVLCFIHPINERSVEPLHGVFISSTLGRLHKMAVVVMVVVIVADCAGRVCNGVNLAVRLGAVLKDDFLAAVASNHSSVALRLTANSESENTRFVAK----QWIGLNDGRPSHNCIVIETAHIGVGISGQEGMQAVLSSDYSFAQFRFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGVFDQDINDQWSIDCPKLYEPGQLNLLFNKREFFICIGQGIYTSVVLFFVPYAAFVEAVRDDGTGLSDHQSLAVAVSTSLIIVVSLQMGLDTAYWTAINHFFIWGSVAVYFAIMFAMYSAGLYSIF-----PSQFRFIGTARNTLNQPSVWLVIALTTIVCIMPIAAFRFLKTDLRPTL 1065          

Query: 2134 KDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESE---RPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLV-KENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPE 3483
            KD    Y + SPDE+ALV      GY    R  +     N E E   + + Y +L V+ F S+RKRM+IIV+ P+ + I++ CKGADS +    S   S++    T  ++++YA  GLR L++ ++ +S+  +  + + Y+ A   +   ++++     E+   + ++G + IED LQD V   I ++++AGI VW+LTGDK ETAINI +S +L ++   L  +  +SKE                       +R   T           V G +L    +  I   FL LA     ++  R +P QKA+IV+L+   N  + TLAIGDGANDV+MI  A +GVGI G EG QAV ASD+A+ +FK+LK LL VHG   Y K +    Y FYK+ ++++  FWF F +AFS  +  +     +FNI  T  P II+ ++D+       M+NP+
Sbjct:  363 KDGKILYNASSPDELALVNCGKYFGYFFKGRDDDN----NIEVEVNGKSVIYQLLGVIEFSSDRKRMTIIVRTPE-NKIMVLCKGADSIVQARLSD--SKV-LGATVQHLESYASGGLRTLLLAEKELSEAEYQNFKEEYRVAASSMIKRDEKM----EEVADRLEIVGTTAIEDKLQDDVDKAIFAMKKAGIKVWVLTGDKIETAINIGFSCQLLNDKMELYVIDGASKEG----------------------LRTSGT----------VVSGESL---FKIRITKQFLKLACSSSVLIACRMSPKQKADIVRLIIANNPSLITLAIGDGANDVNMINAAHIGVGISGVEGQQAVSASDYAIGQFKFLKNLLFVHGRESYRKNSYLVCYTFYKNVLFVMPQFWFGFYSAFSGQVFYEKWIYQIFNIIFTAFPIIIFALFDQQKSRHHFMQNPK 769          

Query:  283 GKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVM-MENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDE-TDG 1347
            G+    +P++FV++V+A+KD  ED +R K+D   N  K L      K FV   W + R G  +++  ++  PAD+ LL S + +GI ++ET NLDGE+NLK +  V+      TF+  +        E PN     F GT+   + ++  +L  N++LLRG +LRNTE V GIV+Y G ++K M N++ +R K SK     NK +I    LL++  ++  +  ++  +T+ T   +          +V R         F T ++ +   +P+ L VT E VK         D E+YD    K L  +  N+ E LGQ+ YVF DKTGTLT N ME+K+  +    Y V   + TDG
Sbjct:    1 GQPTILLPLMFVITVSAVKDIFEDMKRHKSDNVENTRKVLRLDKKTKTFVLDSWKNLRVGQIIQVRQDQYFPADLALLRSANNNGIAYVETKNLDGETNLKHKAAVVDASACTTFRGTL------TCEAPND----FEGTVK-TADNVTYSLDHNSILLRGTSLRNTEWVYGIVIYTGHDSKIMKNSSKSRTKFSK----TNKQIILSFSLLVLHSMNSGLSELV-KLTTHTSTLLVRMTLTRISDSVTR---------FGTWLLLFANFVPISLIVTLEVVKFLW------DAEIYD--VAKDLNTK--NLNEQLGQVDYVFSDKTGTLTCNLMEYKKHSVGKYSYGVDGAQITDG 322          

Query: 1855 ITDTNQKDYVQTPNKSRKVKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSDINTEGDRNNSGIDSFKN---DQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITF-------MSSDIG-IWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAI 3882
            + +  Q +Y+ +       +++++F+S     A    ID I +    T +  + +      D    +N   D ++  I+ F           P    D    Y++ SPDE ALV+     GYK + R PN VT+   E+     Y +L +  F+S RKRMS I + P   +I +FCKGAD+ +      + ++   E T  +++ YA  GLR L +  R IS+  + EW+  Y EA   L N  ++L    + IE +++L+G + IED LQDGV +TI +L+ AGI +W+LTGD++ETAINI  S +L SE+  L+ ++  +++ T   + E     K N  NE     Q  T  +    LAL +DG +L FA+E E++   L +A+ C +V+C R +P+QKA +V++VK       LAIGDGANDVSMIQ A VGVGI G EGMQA  ++D A+ +FK+LK+LLLVHGSW Y +++   LY FYK+T   +  FW+ F NAFS   +++  T   +N+  T  PP + GV+D+ + +  L R P+LY+ G   + +  + FW  I++  + S+++++   + +       M  ++   W +G  +   ++I  L    + T  WT F  + I  S +L WL+F  IY  I       S + Y  +       +FWL  +V P+ A+
Sbjct:  548 VEELGQIEYIFSDKTGTLTRNIMEFKSCS--IAGHCYIDKIPEDKTATVEDGIEVGYRKFDDLKKKLNDPSDEDSPIINDFLTLLATCHTVIPEFQSDGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNSTRKRMSAIFRFPD-GSIKLFCKGADTVILERLDDEANQY-VEATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLIINEETRDDTERNLLE-----KINALNE----HQLSTHDM--NTLALVIDGKSLGFALEPELEDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIYRYGFALNMHGELADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGS-LLFWLIFFPIYASIFPHANI-SREYYGVVKHTYGSGVFWLTLIVLPIFAL 1217          

Query:   70 NGEEQCRKIYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSNSFIEV--ENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDY--AVKDDETDGQSDKVTMRSEFGDTDDKKMND--DHGKKLLKNLIPML 1452
            NGE +   I  S + +S    + Y++N + T KYN  TF+P  LF++F ++AN++F+    +  +P +    +      ++ VL V+A+K+ +ED +R  +D+ +N+S   I+S A   FVE++W   R GD +++ + E IPAD ++L S++  G+C+IET+NLDGE+NLK ++   +E       + L N   +V  E PN  +Y + GT+    +   I L  + ++LRG TLRNT  + G+V++ G ETK + N   T  KR+ +E+ IN+ +I    +LI+L L  SIGNVI +          Y +  +      ++     FL FW   I +  L+P+ L+VT E +K +Q F I  DL++Y  + +    VR  ++ E+LGQI+Y+F DKTGTLT N MEFK   I G  Y   + +D+T    D + +     D   KK+ND  D    ++ + + +L
Sbjct:  179 NGEPRVIHINDSLANSS----FGYSDNHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKIKQ-SRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLNDRQ--IPLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIALFTVLIVLILISSIGNVIMSTADAKHLSYLYLEGTNKAGLFFKD-----FLTFW---ILFSNLVPISLFVTVELIKYYQAFMIGSDLDLYYEKTDTPTVVRTSSLVEELGQIEYIFSDKTGTLTRNIMEFKSCSIAGHCYIDKIPEDKTATVEDGIEVGYRKFDDLKKKLNDPSDEDSPIINDFLTLL 630          

Query: 2155 ESESPDEMALVKTACIHGYKLLQRGPN--FVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTD-----NIIMFCKGADSAMFGNFSKDISEIDQ-ENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEF-------LGNIKSNYPNEIM-------EIRQGKTR-PLIRKDLALSVDGSTLTFAME-DEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITF------MSSDIGI---WEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLGKGSNLYFDYEPELVDVRNPS 4029
            +++SPDE ALV TA   GY  +    +   V I   + E    + VL VL F+S+RKRMS I+K P +        ++ CKGADS ++    +  ++    E T  +++ YA  GLR L + QR ++   +  W K Y  A   + N E+EL  +T  IE +++LLG + IED LQDGV D+I  L  AGI +W+LTGDK ETAINI +S  + + +  L+ + AS ++     ++EF       + N+ + Y  E         E+++ K    L + + A+ +DG  L  A+  +E++  FL L + C +V+C R +P QKA +V+LVK+ L + TLAIGDG+NDV+MIQ ADVGVGI G EG QAVM SD+A+ +F+Y+ RL+LVHG WCY +LA      FYK+ I+ L +FW+   N F  S + +      +N+  T +P I+  V D+D+     M  P+LYR GI  K +    F   +LD ++QS + +   Y+ +        + +G+   +  G  +TA A+ +C  ++ +E   W WF GL I +S  + +  +T I+T         S++ Y    +   +  +W +  V  L  + PR TI+ IR   YP  +   ++RE  L +G    FD  P+  D  +PS
Sbjct:  840 KAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQKE----FQVLNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLICKGADSVIYSRLDRTQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGED-----VEEFGSDPIQVVNNLVTKYLREKFGMSGSEEELKEAKREHGLPQGNFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWDWFCGLFICLSLAVFY-GWTGIWT-----SSSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPRFTIDCIRKIFYPKDIE--IVREMWL-RGD---FDLYPQGYDPTDPS 1476          

Query:  424 QFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSNSF-IEVENPNQEIYKFNGTIFFKSQSIGITLRK-----NNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIW-CVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVK--------------DDETDGQ-------SDKVTMRSEFGD-TDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNE 1566
            +F +  W + + GD V++H N+ IPAD++LL ++D+ G C++ET NLDGE+NLK R+ +          ++    F +E E P+  +Y + G   ++    G  +R      NNLLLRGCTLRNT+  +G+V++ G +TK M+N   T  K+S++ R++N  VI   VLL I+   +  +  V +     ++D+ E+        T+  + +   F++FW +VI YQ+L+P+ LY++ E +K  Q   I  D+ +Y+ + +     +++NI +DLGQI+Y+F DKTGTLT+N MEFK+  I+G  Y                 D E++G+        D+ TM  E    +D+ +   +    + K ++  L G     ++     K  + F L + +C++ +V  NK++
Sbjct:  437 RFAKDYWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDITRTKFWVESEGPHANLYSYQGNFKWQDTQNG-NIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQKPRSRDYFEF-------GTIGGSASTNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGVDVESEGRREKEEIAKDRETMIDELRSMSDNTQFCPEDLTFVSKEIVEDLKGSSGDHQQ-----KCCEHFLLALALCHSVLVEPNKDD 833          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFV 432
            Y  N++RT KY  +TF P N+  QFH FANIYF+ +LIL             A +P++ ++ +TAIKD +ED RR   D  VN+++  I S  K + V
Sbjct:  229 YPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGVKNENV 326          

Query: 2155 ESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTD-----NIIMFCKGADSAMFGNFSKDI---SEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKE------KTHDLIKEFLGNIKSNYPN------EIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDE-IKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITF------MSSDIGI---WEFGQIITACALITCLVHLGIETRFWTWFHGLGIFIS--FILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWL----FWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLGKGSNLYFDYEPELVDVRNPS 4029
            +++SPDE ALV TA   G+  + +    + I     ++   + +L +L F+S+RKRMS IVK P  +       ++ CKGADS ++   S+     SE   E T  +++ YA  GLR L + QR +S   + +W+++Y  A   L N E EL  +   IE +++LLG + IED LQDGV D IE L  AGI +W+LTGDK ETAINI +S  L +    L+ +  +  +      +  +++   L      Y N      EI E ++    P  + + A+ +DG  L  A+  E I+  FL L + C +V+C R +P QKA +V+LVK++L + TLAIGDG+NDV+MIQ ADVG+GI G EG QAVM SD+A+ +F+YL RL+LVHG W Y +LA      FYK+ I+ L +FW+   N F  S + +    + +N+  T LP I  G+ D+D++    +  P+LYR GI  K +    F   +LD ++QS + +   Y+ +       S+ +G+   +  G  +T  A+I+C  ++ +    W WF GL I +S   + AW       T I    +   +      F+   R      FW +  V  L  + PR T ++ +   YP  +   ++RE       + +FD+ P   D  +P+
Sbjct:  795 KAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQK--EFEILNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVIKTTGDDVKEFGSEPSEIVDALLSKYLKEYFNLTGSEEEIFEAKKDHEFP--KGNYAIVIDGDALKLALYGEDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWFSGLFIALSCLVVFAW-------TGIWSSAIASRE-----FFKAAARIYGAPSFWAVFFVAVLFCLLPRFTYDSFQKFFYPTDVE--IVRE----MWQHGHFDHYPPGYDPTDPN 1433          

Query:  424 QFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSNSF-IEVENPNQEIYKFNGTIFFKSQSIG------ITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA 1323
            +F +  W   + GD V++H N+ IPADI+LL ++D  G C++ET NLDGE+NLK R+ +   N      ++    F IE E P+  +Y + G + +++ + G      IT+  NN+LLRGCTLRNT+  +G+V++ G +TK MLN+  T  K+S++ R++N  V+   +LL ILC    I N ++       D     +F     T+  + A   F++FW +VI YQ+L+P+ LY++ E +K  Q   I  D+ +Y+ + +     +++NI +DLGQ++Y+F DKTGTLT+N MEFK+  I+G  Y 
Sbjct:  392 KFAKNYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRTSKDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITI--NNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVY------YDKKGRSRFSYEFGTIAGSAATNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSYG 690          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLI 405
            +Y  N++RT KY  +TF+P N+  QFH FAN+YF+ ++IL            ++ +P+V ++ +TAIKDA+ED RR   D  VN++K  I
Sbjct:  190 QYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNNTKTHI 279          

Query: 2113 NKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEID--QENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLS-LTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYP 3927
            N  P  + D L +Y++ SPDE+A+VK     G  L +R  + +++ +  S + + Y +LQV PF+S+ KRM IIV+  Q D      KGAD+ M    SK +   D  +E T +     AR GLR LV+G++ ++K  + ++ K Y +A   + N ++++   +T  +E D+ LLG++G+ED LQ  V  +IE LR AGI +W+LTGDK ETA  ++ SAKL S  Q +  ++  ++ +      E+L                      I ++  L +DG +L   ++   + +F  +     +V+  R TP QKA++  ++++    +   IGDG NDVSMIQ ADVGVGI G EG QA +A+DF++T+F +L  LLL HG   Y + A+ A ++ ++  I  +    +  C+ F    +      V +    T + P+     D D+        PELY+     KS     F+V +L +++Q SVI +         D        I     ++  L+ + +E   +TW   +   +   +A L+F ++     G       D +D  +     +   LL ++  L +IFP  T   I   L+P
Sbjct:  578 NVTPTFEDDEL-TYQAASPDEIAIVKFTESVGLSLFKRDRHSISLLHEHSGKTLNYEILQVFPFNSDSKRMGIIVRDEQLDEYWFMQKGADTVM----SKIVESNDWLEEETGNM----AREGLRTLVIGRKKLNKKIYEQFQKEYNDASLSMLNRDQQMSQVITKYLEHDLELLGLTGVEDKLQKDVKSSIELLRNAGIKIWMLTGDKVETARCVSISAKLISRGQYVHTITKVTRPEGAFNQLEYLK---------------------INRNACLLIDGESLGMFLK-HYEQEFFDVVVHLPTVIACRCTPQQKADVALVIRKMTGKRVCCIGDGGNDVSMIQCADVGVGIVGKEGKQASLAADFSITQFCHLTELLLWHGRNSYKRSAKLAQFVMHRGLIIAICQAVYSICSLFEPIALYQGWLMVGYATCYT-MAPVFSLTLDHDIEESLTKIYPELYKELTEGKSLSYKTFFVWVLLSLFQGSVIQLFSQAFTSLLDTDFTRMVAISFTALVVNELIMVALE--IYTWNKTM---LVTEIATLLFYIVSVPFLG-------DYFDLGYMTTVNYYAGLLVIL--LISIFPVWTAKAIYRRLHP 1139          

Query:   88 RKIYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQIN---KDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQD--FIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVK---MHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDY 1320
            R+I+P T+    +++ +Y +NE+   KYNA+TF+P  L+EQF  F N+YF+ + +   +P +         +P+ FVL+VT  K+A++D +R + D+  N+   L +   + + +  K    + GD +K+H  + IPAD+VLL S++ SG   I+T  LDGE++ K R    +  N + + ++++   I    P + I+KF G + +K  S    L  +N L     L ++   I  VVY G++T+  +N    + K   LE +IN   K +  CV  L I         ++     F  D  +I+  ++                      +I +  +IP+ L V  +  K    HQ+ H +   E           VR   IPEDLG+I+Y+  DKTGTLT+N M+ K+  +    Y
Sbjct:  155 REIHPDTT--PVYDRNRYVSNELSNAKYNAVTFVPTLLYEQFKFFYNLYFLVVALSQAVPALRIGYLSSYIVPLAFVLTVTMAKEAIDDIQRRRRDRESNNE--LYHVITRNRSIPSK--DLKVGDLIKVHKGDRIPADLVLLQSSEPSGESFIKTDQLDGETDWKLRVACPLTQNLS-ENDLINRISITASAPEKSIHKFLGKVTYK-DSTSNPLSVDNTLWANTVLASSGFCIACVVYTGRDTRQAMNTTTAKVKTGLLELEINSISKILCACVFALSI---------LLVAFAGFHNDDWYIDILRY----------------------LILFSTIIPVSLRVNLDLAKSVYAHQIEHDKTIPETI---------VRTSTIPEDLGRIEYLLSDKTGTLTQNDMQLKKIHLGTVSY 525          

Query: 2434 ENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMD-FLHLAEQCCSVVCARTTPIQKAEIVQLVKE-NLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITF-MS--SDIGIWEFGQI-ITACALITCLVHLGIETRFWTWFHGLGIFISFILA---WLVFTMIYTVICG-KVVCGSDDPYDFIFQNMQRW----LFWLLCVVTPLAAIFPRLTINTIRNSLYPN 3930
            E T   +D ++  GLR LV   + I    +  W+KRY +A+  L + + ++    +EIE  + LLGV+ IED LQDGV++ IE +RRAGI +W+LTGDKRETAINI YS  L  +   ++ L+ + +            NI S       E+  G     +     + +DG+T+     +   M  F+ L  +  SV+C R +P QKA +V  ++  +  + TLAIGDGAND++MIQ AD+GVGI G EG+QA   SD+++ +F++L +LL VHG + Y + ++  L  FYK+  +      +Q    FS S + +P +  +FN   T LP +  G+++KDL   TL+  PELY  G   + +    F   ++ A   S +I  +  + + MS  SD  ++  G I  TA   +  +    +E     W      F S +L+   WLV+       C   ++  +D  YD  +     +     FW   +V  L  I   +   T +  ++P+
Sbjct: 1019 ERTLQAIDEFSTEGLRTLVYAYKWIDIGQYENWNKRYHQAKTSLTDRKIKVDEAGAEIEDGLNLLGVTAIEDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLIKDYSTVVILTTTDE------------NIISKMNAVSQEVDSGNIAHCV-----VVIDGATMAMFEGNPTYMSVFVELCTKTDSVICCRASPSQKALMVSNIRNTDPNLVTLAIGDGANDIAMIQSADIGVGIAGKEGLQASRVSDYSIGQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQLIYQRYTMFSGSSLYEPWSLSMFNTLFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQGFNWLIFMEWVILATTNSLIITFLNVVMWGMSSLSDNTMYPLGLINFTAIVALINVKSQFVEMHNRNWL----AFTSVVLSCGGWLVWC------CALPILNNTDQIYDVAYGFYNHFGKDITFWCTSLVLALLPITLDIVYKTFKVMIWPS 1504          

Query:  433 EQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSN--SFIEVENPNQEIYKFNGTIFFKSQS----IGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNN-NDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDY 1320
            ++KW   R GDFV L  ++ +PAD++LL  +  +  C +ET  LDGE+NLK ++     N  T     L+N  + + VE+PN ++Y F G +  K+      +   L  +N++ RG  LRNT+ V+G+V+++G+ETK  +N   + R K  KL+R+IN  +++ V ++  + L   +G+V+       Q+   Y    D+       P + +F      +I Y  +IPL LYVT E +K+ Q   +  D++MY  E     E R   I E+LGQ+ Y+F DKTGTLT+N+M F++  + G  +
Sbjct:  296 QKKWEKLRVGDFVLLTQDDWVPADLLLLTCDGENSECFVETMALDGETNLKSKQPHPELNKLTKAASGLANINAQVTVEDPNIDLYNFEGNLELKNHRNDTIMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKIRMNALKNPRTKAPKLQRKINMIIVFMVFVVATISLFSYLGHVLHKKKYIDQNKAWYLFQADAGVA----PTIMSF------IIMYNTVIPLSLYVTMEIIKVVQSKMMEWDIDMYHAETNTPCESRTATILEELGQVSYIFSDKTGTLTDNKMIFRKFSLCGSSW 588          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWN-PES----ERPMTYTVLQVLPFDSNRKRMSIIVKCP-QTDNIIMFCKGADSAMFGNF------SKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKD 2517
            Y+S SPDE+ALV  A   GY +L R    +TI   P+      +   Y +L  + F+S RKRMS++V+ P Q + +++ CKGAD+ +          +K +++I   +TK+  DA A + L+     +R++ ++
Sbjct:  758 YQSSSPDELALVTAARDLGYIVLNRNAQILTIKTFPDGFDGEAKLENYEILNYIDFNSQRKRMSVLVRMPNQPNQVLLICKGADNVIMERLHDRELAAKKMADI-CTSTKERKDAEAELVLQQRKSLERMVDEE 890          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNH 390
            Y +N + + +Y   +F+P  L+ QF + AN YF  + +L  +P     G     IP+   + ++  ++A +D+RR + D+  N+
Sbjct:  138 YCDNRITSSRYTFYSFLPRQLYAQFSKLANTYFFIVAVLQMIPGWSTTGTYTTIIPLCVFMGISMTREAWDDFRRHRLDKEENN 221          

Query: 2149 SYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF---------------GNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIK-----------SNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPR 3891
            SYE+ESPDE ALVK AC +GY+LL R PN VTI+ P  E  + + VL VL FDS RKRMS++V+ P    ++M+CKGADSA+                G  S  +++ID+     ++  YAR GLR L M +R +S   + +W   +K AE  L + E+ L     ++ES+M LLG +GIED LQDGV +TI  LR  G+ VW+LTGDK+ETAIN+ Y++KL   + + I L+A +K++    I  +L ++K           ++Y     + R    +PL      L +DG TL +A+E  +   FLHLA +C  V+C R TP+QKA +V+LV++ L++ TLAIGDGANDVSMIQMADVG+GI G EGMQAVMASDFA+ +F++L +LLLVHG WCY+++ +  LY FYK+ +++L++FW+Q  N FS S  ID L+ + FN+  T  PPI+ G+ DKDL A  L  NP+LY+ G   + Y    FW  ILDA++QS +++  C++ F          G  +   A++   VHLG+ T  WTW H       F+   +  + I+ ++ G VV  +   +      M    FW LCV+  +AA+ PR
Sbjct:  668 SYEAESPDEAALVKMACSYGYRLLSRSPNSVTIFIP-GEGVVKFKVLHVLSFDSTRKRMSVVVRRPSDGAVLMYCKGADSAVLTRLTHASYADEAVEGGVKSTLVNQIDR-----HLTMYARDGLRTLCMAKRELSDSEYHDWLTEHKRAETALQHRERLLQESAQKLESNMELLGATGIEDRLQDGVPETIAKLREGGLKVWVLTGDKQETAINVGYASKLLDASMQKITLNAKNKDECSCQIYSWLNHLKIEPTVSSISGSTSYTTVSFDSRITADQPL-----GLIIDGPTLIYALEKPLNEKFLHLASRCQVVLCCRATPMQKASVVELVRDGLKVMTLAIGDGANDVSMIQMADVGIGITGQEGMQAVMASDFAIARFRFLAQLLLVHGHWCYDRITKMILYFFYKNAMFVLVLFWYQLYNGFSGSNAIDDLSLIFFNLIFTAAPPIVCGILDKDLPATLLKDNPQLYKAGQEGQLYSRKLFWATILDALYQSVILFFACFLLFEGMPADDRMVGITMHQAAVVLASVHLGLMTAQWTWIHHF-----FLWGSVFLSFIWAIVFG-VVQPTHKIHYVSLVTMATKEFWALCVMITVAALLPR 1257          

Query:  145 NNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDY----------AVKDDETDGQ-----SDKVTM-RSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDI-EIKE-----------------EEMSRMKNVKDFFLLMGICNTTVVSLNKNEK-HP 1575
            +N+++T KY   +FIP NLFEQFHRFANIYF+FI+ LN++P I AFGKE+A +P++FVL+VTA+KD  ED RR+ +D++VN++ C +YS A   ++  KW     GD +KL +NE IPADI+LL+S+D + IC++ET+NLDGE+NLKQREVV  + + +  F P    N  ++ E PN  IY+F+G I     S  + + K NLLLRGC +RNT+ V G+VVYAG +TKAMLNN+  R K SK+ER +N DVI CV++L  LC    +G  IWT  +   DF   +  P    +      M+ F+ FWT +I  Q LIP  LYV+ E VK+ QVF I  DL++Y  E ++ +  RA NI EDLGQI+YVF DKTGTLTEN+M FK+  I G +Y          A   D  D Q     S +VT+ +S         +   H    + ++   +H  + E+ E                 +  S++  V++FF+L+ ICNT VV  NK+ + HP
Sbjct:   38 DNKIKTTKYTIWSFIPKNLFEQFHRFANIYFLFIVGLNWVPAINAFGKEIAMLPLIFVLAVTAVKDLFEDRRRYNSDKKVNNTICQVYSSASASYIATKWKDVVVGDIIKLSSNEIIPADILLLNSSDENNICYVETANLDGETNLKQREVVNGLFKEDERFSPRNF-NFKLKCETPNNHIYRFHGAIEL-DDSHTLAVGKENLLLRGCIVRNTKNVEGVVVYAGHDTKAMLNNSGPRSKHSKVERDLNLDVIACVVILFTLCFLGGLGCGIWTQNN---DFFNAHFAPGGESSA----PMEGFIRFWTFIIILQVLIPYSLYVSAELVKLGQVFLISSDLQLYHEETDQPVICRALNINEDLGQIKYVFSDKTGTLTENKMVFKKCTIGGVNYPHESAQDLPDAGPSDTEDEQYMQQVSSQVTLEKSRLAPLGFVALFGYHFPSPILSISCFIHCSLREMSELPYDADLAQVISGDSYKDNGSQLSFVREFFILLSICNTVVV--NKHARPHP 540          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQ-TLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSS-------DIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRW---LFWLLCVVTPLAAIFPRLTINTIRNSLYPNL 3933
            Y++ SPDE ALVK A   G+    R P  V I     E    Y +L VL F+S RKRMS+IV+ P+   I ++CKGAD+ +F    ++  ++  E T  +++ +A+ GLR L +    +  + +SEW K Y +A   L N   ++      IE ++ LLG + IED LQ+GV ++I +L  A I +W+LTGDK+ETAINI Y+ +L +   +L+       ++T D I+E+L        NE + +  G+      +     VD   L  A+ DE+K++FL LA  C +V+C R +P+QK+++V+LVK +++   TLAIGDGANDV MIQ A VGVGI G EG+QA  ASD+A+ +F+YL +LL VHG+W Y +LA+  LY FYK+    ++  WF   N FS  ++ D     ++N+  T +PP+  G++D+ + ++++++ P+LY+   N + Y    FW+ I+ +++ S +++ + +              +G W  G ++    +IT  +  G+E   W W   L I+ S I +W +F +IY +     +       D I Q+ Q +   +FW+   + P+  +        I+ + +  L
Sbjct:  472 YQAASPDEGALVKGAKKLGFSFNVRTPTSVIINAMGKEE--VYEILNVLEFNSTRKRMSVIVRTPE-GKIKLYCKGADTVVFERMREN--QLYLETTVKHLEEFAKEGLRTLCIAMSELDPEEYSEWSKIYYQASTSLENRADKVDEAAELIERNLFLLGATAIEDKLQEGVPESIAALADADIKIWVLTGDKQETAINIGYACRLLTGEMKLL----MCNDETLDGIREWL--------NEHLRM-IGRNGIKCERMCCFFVD-QVLLQALTDELKLNFLDLALCCKAVICCRVSPLQKSQVVRLVKHHVKDSITLAIGDGANDVGMIQAAHVGVGISGQEGLQAASASDYAIAQFRYLNKLLFVHGAWSYQRLAKLILYSFYKNVCLYVIELWFAMENGFSGQILFDKWCIGIYNVIFTSVPPLAIGLFDRTVSSESMLKYPKLYKTSQNAEIYNTKVFWLWIMTSVYHSLLLFYLPFGMLKHEVPYSNGLVVGQWHLGNVVYTLVVITVCLKAGMELDAWNWVCHLSIWGS-IASWFIFLLIYCLPGMAFIIAP----DMIGQDTQLYSSGVFWMSVFIVPVITLMADYLYRLIKRTFFKTL 1052          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREV-----VMMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFG-DTDDKKMNDDHGK-------KLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTV 1545
            +Y NN++ T KYN +TF+P  L EQF R++N++F+FI +L  +  +   G+    +P++ VLS +AIK+ +EDY+R  AD  VN+ +  +      Q     W   + GD VK+      PAD++LL S++  G+C++ETSNLDGE+NLK R++     + ++  +           +E E PN  +Y F G I    +   + L  + +LLRG  LRNT+ V G+V Y G ++K M N+     KRS ++   N  +++   LL+ L L  +IG  +W   +   +   +Y   + +      P     L F T +I Y  LIP+ L VT E VK  Q   I  D++MY   ++     R  N+ E+LGQ++Y+F DKTGTLT N MEF++  I G  Y            ++++R  F    +D   N+  G+        LL NL            E       +++F  L+ +C+T V
Sbjct:   12 QYCNNKISTAKYNFLTFLPKFLLEQFSRYSNVFFLFIALLQQIDGVSPTGRYTTAVPLLLVLSCSAIKEIIEDYKRHAADGLVNNRRVKVLRDNTLQ--SLLWIEVQVGDIVKVVNGHFFPADLILLSSSEPMGMCYVETSNLDGETNLKIRQMFNSLSLFIDCISKISGHCYLQGRVECEGPNNRLYDFVGNIALTGKK-PVPLSADQVLLRGAQLRNTQWVFGLVAYTGHDSKLMQNSTAAPIKRSNVDHTTNIQILFLFGLLMALALCSTIGFYVW---AGEHEHAHWYLGYEEL------PPQNYGLTFLTFIILYNNLIPISLTVTLEVVKFIQAIFINLDIDMYYAPSDTPAMARTSNLNEELGQVKYIFSDKTGTLTRNVMEFRKVTIGGISY------------RLSVRPFFVLQNNDHLKNNSCGEGQSFSDPALLDNL-----------REHHPTASVIREFLTLLSVCHTVV 459          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVK-ENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRN-GINCK-SYKPWHFWVNILDAIWQSSVIYVICYITFMS------------SDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGL---GIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIR 3954
            Y++ SPDE ALV+ A   G  ++ RG     +          YT+L VL FDS RKRMS+IVK  +    +M  KGA++A+         ++    T D++D YA  GLR L + QRV + + + +   +  +A Q + + E++L  +  E+E ++ LLG + +ED LQ GV +TIE++R AGI VW+LTGDK +TA+NI++S   F     L+ ++  S                S    E+++ +Q K +    K   L VDG +L        ++ F+ + + C +V+C R +P+QKA++VQLVK    +  TLAIGDGAND  MIQ A VG+G+ G EG QAVM SD+A+++F++L R+LLVHG W Y + A    Y FYK+  +I   F + F NAFS   +        +NI  T LP +I+G++++ +  D L   P LY++   N + S+  + +WV      W + V +   Y+ F               ++GIW FG  + A  +I   + L + T +WTW   +   G  ++F L  +VF    T    +V   S D Y   F      + WL  ++  L ++ P +    I   L+P    K  +R
Sbjct:  494 YQASSPDEKALVEAAVRFG--IVYRGKVGEDMEVQMQGTSHRYTLLHVLEFDSTRKRMSVIVKTAE-GQYLMLTKGAETAILDRLESGPKDV----TADHVDGYAEQGLRTLAVAQRVFTPEEYRDVDAKLTKAGQAINDREQQLAEVFEEVECNLHLLGATAVEDKLQAGVPETIEAMREAGIKVWVLTGDKEQTAVNISHSCGHFKHGMDLMFVTRRSS--------------PSECEQELLQFKQ-KVQSQPDKLFGLIVDGMSLVHIFNGHKEL-FIEVCKFCMAVLCCRMSPLQKAQVVQLVKVSKEKPVTLAIGDGANDCGMIQEAHVGIGVMGKEGRQAVMTSDYAISRFRFLARVLLVHGHWYYIRSAILVQYFFYKNVCFITPQFIYAFFNAFSGQPLYHGFLLTCYNIFFTSLPILIFGIFNQHIGGDILQGRPSLYQDVAKNSRLSWVQFIYWVA--SGYWHALVFFFGGYLMFQGDLFDLLKPISILQNVGIWSFGTFVFAVCVIVSNLKLALVTHYWTWLTHVVTWGSILTFFLFAIVFNSFQTTFGDQV---SIDMYQVFFTLFNEGVVWLGLLLLILISLLPDVFGMIIGRHLFPTETQKAQVR 1084          

Query:   76 EEQCRKIY-----PSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFV--LSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTF--KPEMLSN--SFIEVENPNQEIYKFNGTIFFKSQSIG--ITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRN--PAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETD------GQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEK 1569
            EE+ R +Y     PS   +   ++ +YA+N + T KY    FIP NLFEQF R AN YF+ I        I+  G  +    V          +    EDY R K D+ VN   C +      + ++ K    + GD V++  NE  P D+++L S+D  G CHI T+NLDGE+NLK R  V   +   F   PE LS+  + IE ++P+ ++Y ++G I F +       +L   NLLLRG  L+N++ V G+ VY GKETK  LN  +   K S +E+ +N         LI+  L   +   I T   + ++     K P +  + I +    ++ FL F   +I Y  +IP+ LYVT E  K         D++MY+ + ++       ++ E+LGQ++YVF DKTGTLTEN M+FK   I+G  Y  K++E +      GQ   + M S                   K  + +L+  I+          +V DF+L + +C+T   S + +++
Sbjct:    2 EEEWRTVYVSNRYPSNDPDVAIKQKRYADNMIVTSKYTIWNFIPKNLFEQFRRIANFYFLCI------GTIQVRGGSLIKSVVAGTDFYHTKCVAKGYEDYLRHKVDKEVNSRPCGVVFDGIVKDIQSK--DIKVGDIVRVKDNEEFPCDLIVLASDDPEGKCHITTANLDGETNLKVRSAV---SRTAFLHSPEKLSSLQATIECQHPHVDLYGYSGRIIFNANGENEITSLGPQNLLLRGARLKNSDHVFGVAVYTGKETKMALNQAEAPHKFSTVEKTMN-------TFLIVFLLVLVLQGAICTGLKYWKESTVPGKAPYANDSGIASFKGVIEDFLVF---LILYNYVIPISLYVTVELQKFIGALFFAWDVKMYNPDTDEPAIANTSDLNEELGQVEYVFTDKTGTLTENDMQFKECSINGKKY--KENEMELCVDGPGQPASILMPSASVSLGQFNHVGHLQSTPFKTKMSILYNYIQ----------DVLDFYLALALCHTVQASKSSDQE 487          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQ-RLIELSASSKEKTHDLIKEFLGNIKSNYP-----NEIMEIRQGKTRPLIRKD-----------LALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKY----LKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELY----RNGINCKSYKPWHFWVNILDAIWQSSVIY-VICYITFMS-----SDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFI-FQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLGK 3972
            Y+++SPDE ALV  A   G+   +R P  +TI     E    + +L +L F+++RKRMS+IV+  Q D I ++CKGADS ++       + +  + T+D ++ +A  GLR LV+  + I+   +  W  +Y +A   + N E+++ ++  EIE +++L+G + IED LQDGV D I +L  A I +W+LTGDK ETA+NI YS +L +++   +  ++  S +   + I  +   +++        N  +  R+G +R   + D             L + G +L FA+  +++++FL LA  C +V+C R TP+QKA +VQLVK+N +  TLAIGDGANDVSMI+ A +GVGI G EGMQA +ASD++  +F+Y    + RLLLVHG W Y ++ +   Y FYK+  + L+  W+ F   +SA  + D      +N+  T  P +   ++D+D++ +  +R P+LY    +N +  K    +  +   L ++W   + Y V+ ++T  S     S++    FG  + A  ++   V + ++T++WTW +    + S I  ++ + + Y+        G  + Y  + FQ     +FWL  ++       P +    IR+   P L     +R ++ G+
Sbjct:  481 YQAQSPDEAALVTAARNFGFVFKERSPTTLTIVAMGQEE--QHELLAILDFNNDRKRMSVIVR--QNDKIKLYCKGADSIIYERLHPSCTSLMDKTTED-LNKFAAEGLRTLVLAYKDITPQDYQAWKSKYDKACVAMDNREEQVQAVYEEIEKNLILIGATAIEDKLQDGVPDAIATLAAANIKIWVLTGDKPETAVNIGYSCQLLTDDMTEVFMINGDSMDAVRESINMYKSKVQAGLDDKAAHNNSVSFRKG-SRETAKSDSGGKTDGGNAGFGLVITGKSLVFALNKQLELEFLELACMCKAVICCRVTPLQKALVVQLVKDNKKAVTLAIGDGANDVSMIKAAHIGVGISGQEGMQATLASDYSFAQFRYPLHSIVRLLLVHGRWSYMRMCKFLNYFFYKNFAFTLIQLWYAFFTGYSAQTLYDAWFISFYNVLFTSGPVVFLAIFDQDVNHENCIRYPKLYVPGQQNIMFNKRVFAYSLFYGSLTSLWLYFLAYGVLGFVTIDSVGRDTSNLKF--FGTAVAATLVVVVNVEISLKTQYWTWINHFFTWGSIIFYFIFYFIYYSQFFFNR--GPQEHYFGVQFQVFGNPVFWLYLLIAAFVTNIPSICEKLIRSEYKPTL--SDAVRRKQQGR 1107          

Query:  121 NFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNH--SKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSNSF---IEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWT--VTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTS-VIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYA 1323
            N   + Y +N +RT KY  ITF+P NLFEQF R AN+YF+  +I+  +PEI A   E   +P+VFV+  TAIKDA +D RR ++D+ VN+  SK LI +  +    E KW   +CGD +K+  NE IPAD ++L +++ +G+C+IET+ LDGE+NLK R+  + + N     E L   F   +  E PN  + KFNG I F +Q    +L  +NL+LRGC LRNT+ V G VVYAG+++K M+N+  + FKR+ L+R +NK +I   +LL  +C+  SIG  IW   V    Q F+++       P    N  +      W S ++    LIP+ LY++ E ++M Q   I  D  MY  + +     R   + E+LGQI+Y+F DKTGTLT+N M FK+  I G  Y 
Sbjct:   17 NEAHHHYKDNFIRTSKYTIITFLPKNLFEQFQRVANMYFLLQVIIMSIPEITALKPESTAVPLVFVIGFTAIKDAYDDIRRHQSDRDVNNRKSKALIGNSRE----EIKWMKIKCGDVLKIDNNEQIPADFLILSTSEENGLCYIETAELDGETNLKCRQ-PLPDTNEMGDDEALLAKFKGTVHCEPPNNILDKFNGKIAFDNQE--YSLDNDNLILRGCVLRNTDWVYGTVVYAGQDSKLMMNSGVSTFKRTNLDRLLNKLIIGIAVLLACICIVLSIGTTIWEELVGQNFQVFLQW-------PNFYMNNVVFIGTCHWPSFIMVLNTLIPISLYISVEVIRMGQSIWINWDQYMYYEKKDTPARARTTTLTEELGQIEYIFSDKTGTLTQNVMTFKKCSIHGKMYG 411          

Query: 3055 EIVQLVK-ENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRN-GINCK-SYKPWHFWVNILDAIWQSSVIYVICYITFM-----SSDIGIWEFGQIITACALITCLVHLGIETRFWTW 3702
            ++VQLVK    +  TLAIGDGAND  MIQ A VG+G+ G EG QAVM SD+A+++F++L R+LLVHG W Y + A    Y FYK+  +I   F + F NAFS   +        +NI  T LP +I+G++++ +  D L   P LY++   N + S+  + +WV      W + V +   Y+ F      S ++GIW FG  + A  +I   + L + T +WTW
Sbjct:    6 QVVQLVKVSKEKPVTLAIGDGANDCGMIQEAHVGIGVMGKEGRQAVMTSDYAISRFRFLARVLLVHGHWYYIRSAILVQYFFYKNVCFITPQFIYAFFNAFSGQPLYHGFLLTCYNIFFTSLPILIFGIFEQHIGGDILQGRPSLYQDVAKNSRLSWVQFIYWVA--SGYWHALVFFFGGYLMFQGDLFGSINVGIWSFGTFVFAVCVIVSNLKLALVTHYWTW 227          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDY----------AVKDDETDGQSDKVTMRS--------------------------EFGDTDD-----KKMNDDHGKKLLKNLIP---------------MLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVIXXXXXXXXXXXXXXXXXAGEGVMNKAASISSFSAKNIFTKSGKVSMKNSDNTEIESKVHDVLFDRNDH-SLELLNFKRNDSALPDFDDIHIRITDTNQKDYVQTPNKSRKVKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSDINTEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF--------GNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIF---QNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREE 3960
            KY  N + T +Y+ +TFIP+NLF+QFHRFAN+YF+F+ +LN++P +EAF KE+  IP++ VL+V  IKDA+EDYRR+ +D++VN++   ++  A+K +V+  W   R GDFV+L  NE IPAD+VLL+S+D  G+C+IET+NLDGE+NLKQR+VV  +   ++ F P    +S IE ENPN ++ +F G I   +  + + L  +N+LLR CT+RNTE VIGIVVYAG ETKAM+NN+  R+KRS LER++N+D++WCV LLI++CL  ++G+ +W         ++  K P        +PA+ AF  FWT +I  Q LIP+ LYV+ E VK+ Q++ I  DL+MY+ E +  ++ RA NI EDLGQIQYVF DKTGTLTEN+M F+R  I G +Y            ++D   G S  VT++S                          E G+ D      +         + K+++P               +   D   K      +  + DFFL + ICNT VVS     +H + + +      +  K        VM +  S S F      T      MK+S            LF R    SL       N  + P+             + Y +T   S KV+  +    GD ++AD +S + + +  + +++    +E         D + +G   +SG DS            + +LL  YE+ESPDE ALV  A  +   L  R P  + +  P     +   +L VLPFDSNRKRMS++V+ P T  ++++ KGADS +            ++++    +E T+ ++DAYAR GLR L + ++V+ ++ +  W KR   AE  + N E+ LL     +E+++ LLG +GI D LQ+ V +TIE+L+RAGI VW+LTGDK+ETAINIA + KL   + +L+  +  +K+    L+ E +  ++      + E R+  +         L++DG TL +A++++++  FL L+ +C +V+C R+TP+QK+++VQLV+++LR+ TLA+GDGANDVSMIQ+ADVG+GI G EGMQAVM+SDFA+ +F  L++LLLVHG WCY++LA   LY FYK+ +Y+ L+FW+QF   FS S+MI+    +LFN+  T +PP+IYGV D+D  AD L  +PELY+   + K Y P  FW+ ILDA +QS V + I Y     SD+    FG  I   AL   L+H  IE+   TW H L +F+S   ++  F ++++  C  +VC    P + +    + +   LF+++C VT + A+ PR+   ++ N+++P+ L     R+E
Sbjct:   63 KYQGNAICTTQYSLLTFIPMNLFQQFHRFANLYFLFLALLNWVPVVEAFEKEITMIPLLVVLAVIGIKDALEDYRRYLSDKKVNNNMVEVFCGAQKDYVDCCWKDVRVGDFVRLSCNEIIPADMVLLYSSDPRGVCYIETANLDGETNLKQRQVVSDLPLQDSQFSPGNF-HSRIECENPNNDLNRFRGFIE-HANGVRVGLHSSNVLLRSCTIRNTETVIGIVVYAGHETKAMMNNSGPRYKRSLLERRLNRDILWCVALLIVMCLIAAVGHGLW---------LKNLKDPIFQVDGEMSPALAAFYVFWTMIIVLQVLIPISLYVSIEIVKLGQIYFIHNDLDMYNEEQDSRIQCRALNITEDLGQIQYVFSDKTGTLTENKMVFRRCSIFGVEYPHEENARRLAVYEEDPNRGASRTVTLKSACSRKSLTCRSLSCNRSSVSLHTLTAESGEEDQLSSHPQAKTGAFCSPMAKDVVPDPALEKKLNSLCSSLLHLSDGLFKTTSNLELTYITDFFLALTICNTVVVSSPGQPRHVMREARTPLKSLEELK--------VMFQRLSFSPF------TTMSTPQMKSSPR-----GFTSRLFIRGKSGSLTFPTPTNNSPSCPN----------PGPESYEET--SSLKVELNMSAGRGDPIWADPDSKEALKEAQISSDRFKGSME---------DQDEDG---SSGEDS------------EDELL--YEAESPDEAALVHAARAYHCTLRARSPENLLVELP-GIGSLPVRLLHVLPFDSNRKRMSVVVRHPLTGEVVVYTKGADSVIMDLAERPKGAEHAQELYSHIREQTQKHLDAYAREGLRTLCIAKKVLEEEEYDVWMKRQLLAESSIENREELLLESAQRLETNLTLLGSTGIVDRLQEEVPETIEALQRAGIKVWVLTGDKQETAINIANACKLLRSSDQLLTANCDNKDACAALLNELIVEVQCGQEG-VSEQREDPSSG--STGFILAIDGRTLDWALQEDLRSSFLELSRKCKAVLCCRSTPLQKSKVVQLVRDHLRVMTLAVGDGANDVSMIQVADVGIGISGQEGMQAVMSSDFAIPRFHLLRKLLLVHGHWCYHRLANMILYFFYKNVMYVNLLFWYQFFCGFSGSVMINSWVLILFNLLFTSVPPLIYGVLDQDTAADALEEHPELYQTARSSKVYVPSIFWITILDAFYQSCVCFFIPYFALAGSDVESLSFGSPINTSALFIILLHQVIESHTLTWIHALVLFLS-AASYFAFVLLFSTFC--IVC--SHPTNLLGVEPRQLSTPLFYVICAVTTVTALIPRILFRSLFNTVHPSALLTKDQRQE 1330          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF--------GNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKS------------NYPNEIMEIRQGKTRPLIRKD-------LALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            YE+ESPDE ALV  A  +   L+ R P+ VT+  P   + + + +L  L FDS RKRMS++V+ P TD I ++ KGADS +         GN      +     T++Y++ YA  GLR L + ++V+SKD ++ W + + +AE  +   E+ L      +E+++ LLG +GIED LQDGV +TI SLR+AG+ +W+LTGDK+ETA+NIAY+ KL    + L+ L+A S+E    L++E L  I++            ++   +       + PL           L L +DG TL +A++  ++  FL +A  C SV+C R+TP+QK+ +V+LV+  L++ TLAIGDGANDVSMIQ+ADVGVGI G EGMQAVMASDFA+ +F+YL++LLLVHG WCY++LA   LY FYK+ +++ L+FW+QF   FS S MID    + FN+  +  P +I G  DKD+ A+TL + P+LY +G N + YKP+ FW+N++DA +QS V + I Y  +  SD+ ++ +G  IT  AL+T L+HLGIET+ WTW + L I  S  L + V  + Y   C      S +PY  I + +Q  +F+LLC + P+AA+ PR       ++L+PN +  G
Sbjct:  681 YEAESPDEAALVYAARAYKCSLVGRLPDQVTVELPHLGK-LNFELLHTLGFDSTRKRMSVVVRHPLTDQITVYTKGADSVIMELIRPPITGNSKGRRQKKILCRTQNYLNLYAADGLRTLCIAKKVLSKDEYARWLQHHLQAETAIQRREELLFESALRLETNLQLLGATGIEDRLQDGVPETIASLRKAGLQIWVLTGDKQETAVNIAYACKLLDPEEELLTLNADSQEACKLLLEESLHYIQAKFLCSSGDASAKDFHANVSSFEIYPSSPLSSHAASDSVHRLGLVIDGRTLAYALDASLEDTFLTVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFRYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMIDQWYLIFFNLMFSSFPQLISGTLDKDVSAETLQQLPQLYTSGQNSEEYKPYMFWMNMIDAFYQSLVCFFIPYFAYTDSDVDLFTWGTPITTIALLTILLHLGIETKTWTWMNCLSIAFSVALFFTV-ALCYNASCPTCYPPS-NPYWTIQRLLQDPVFYLLCTIAPVAALLPRYFYRACHSTLFPNPVQVG 1302          

Query:  136 KYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPT--VIR------NPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKL 1428
            +YANN ++T KY  ++F+P NLFEQFHR AN+YFVFI +LNF+P +  F  E+A  PV+F+LSVTAIKD  EDYRR ++D  +NH  CL+YS A+K +VE+ W   R GDF++L  NE +PAD++LL S+D   +CHIET+ LDGE+NLKQR+VV    + +  F P +  NS IE E PN ++ +F G I  +S      L K NLLLRGCT+RNTEE +GIV+YAG ETKAMLNNN  R+KRSKLERQ+N DV WCV++L+++CL  ++G+ +W            +++ D  P   V+       +P M A   F T +I +Q LIP+ L+V+ E VK+ QV+ I +D ++YD E +  L+ RA NI EDLGQ+QY+F DKTGTLTEN+M F+R  + G +Y+      D  + ++ M  E    +++ ++  HG  L
Sbjct:   51 RYANNRIKTTKYTVLSFLPKNLFEQFHRLANVYFVFIALLNFVPVVNTFLPELALAPVLFILSVTAIKDIWEDYRRHRSDMEINHMDCLVYSRAEKGYVEKYWKEVRVGDFIRLRCNEILPADVLLLSSSDPDRLCHIETATLDGETNLKQRQVVRSFFDLDCDFDP-LKYNSVIECEKPNNDLNRFRGYIIHQSGKKD-ALYKENLLLRGCTIRNTEEAVGIVIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFAALGHGLWM-----------FQYGDKRPVFDVLSPEGTNLSPIMSAIYLFLTMIIVFQVLIPISLFVSIEIVKICQVYFIHQDADLYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYS-----HDANAKRIAMYQEMDSEEEECIS--HGGTL 471          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEID-QENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPL---IRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            YE+ESPDE ALV  A  +G+ LL R PN VT+  P  E  + + VL  L FDSNRKRMS++V+ P T   +++ KGAD A+         +     +T+ ++D YA+ GLR L + ++++S   +  W    K A   +   E+ +++   ++E+++ LLG +GIED LQ+ V DTI +LR AGI VW+LTGDK ETA+NI Y+ +L  E   +I +++   + T   I +            + E+R+    P      + ++L +DG TL  A+  +++  FL LA++C SV+C R TP+QK+ +V+LV++ L++ TLA+GDGANDV+MIQ+ADVG+GI G EGMQAVMASDFA+T+FK+LK+LLLVHG WC+ +LA   +Y FYK+  Y+ L+FW+QF   FS + MID    + FN+  T  PPI++G+ DKD+ A+ LM  PELYR G     Y    FW+++LDA +QS V + + Y+ +  SD+ I+ FG  +   +L   L+HLGIE + WT  H + I +  +  + + T+ Y+ IC  V C    +PY  +   M   +F+L+C+++ + A+ PR T   ++NS+ P+ L + 
Sbjct:  621 YEAESPDEAALVYAAKTYGFTLLARTPNSVTVRVPSGEE-LVFEVLDTLAFDSNRKRMSVLVRHPITGEYVLYTKGADYAIMELLGTPGQQKKIAADTQYHLDCYAKDGLRTLCITKKIVSSREYQSWLADRKRALAAIDGREELMMASAVQLETELTLLGATGIEDRLQESVPDTITALREAGIKVWVLTGDKPETALNIGYACRLMEEGDLVINMTSVVFQVTCVSILD----------CTLEEVRRYHEDPRNVDTTQKISLMIDGDTLAIALSPDLQDRFLDLAKRCRSVLCCRVTPLQKSRVVKLVRDKLKVMTLAVGDGANDVNMIQVADVGIGISGQEGMQAVMASDFAITRFKHLKKLLLVHGHWCHTRLANMIIYFFYKNAAYVNLLFWYQFYCGFSGTAMIDYWLMIFFNLFFTSTPPIMFGIMDKDVSAEMLMGVPELYRTGQGSGEYNFRTFWISMLDAFYQSLVCFFVPYLAYQGSDVDIFTFGTPLNTSSLFIILLHLGIEIKSWTVVHWI-IMLGSVALYFIVTLAYSAIC--VTCNPPSNPYWILQNQMADPMFYLICIISTVVALLPRYTFYVLKNSIAPSPLIQA 1209          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETD------------GQSDKVTM--------RSEFGDTDDKKMNDDHGKKLLKNLIPML--HGDIEIKEEE-----MSRMKNVK--------DFFLLMGICNTTVVSLNKNEKHPV 1578
            +  N ++T KY  + FIP+NL+EQFHR AN+YFV + ILNF+P + AF  EVA IP+  ++ +TA+KD  ED+RR+++D+++N+  CLIYS   K ++E++W   R GDFVK+  NET+PAD++LLH++D + +CHIETSNLDGE+NLKQR  +  +  +N+ F+PE   N  +  E PN  +  F   +  K           +LLLRGCT+RNTE  IG VVYAG ETK+MLNNN  R+KRSKLER++N DV +CVLLL I+CL  S+G+ +W + + +   +  +   DS    + +P++ +F  F+T +I  Q LIP+ LYV+ E VK+ Q+F I  D+++YD E +  ++ R+ NI EDLGQI+Y+F DKTGTLTEN+M F+R  I G DY  K++  D             Q  KV +        R      +      D G  +L  ++     H + ++  +E     +SR +           DFFL + ICN+ VVS+   ++  V
Sbjct:   46 FKPNAIKTNKYTPLFFIPMNLYEQFHRLANVYFVGLAILNFIPVVNAFQPEVALIPICVIMFLTALKDGWEDFRRYQSDKKLNNMPCLIYSRTAKHYIERRWKDVRVGDFVKVVCNETVPADLLLLHTSDPNNVCHIETSNLDGETNLKQRNALPGLCTSNDVFEPESF-NCTVVCEKPNNNLNHFKCFV-EKPDKEKTGAGIESLLLRGCTVRNTEHAIGFVVYAGHETKSMLNNNGPRYKRSKLERRLNVDVFFCVLLLFIMCLIGSLGHYLW-LKNLSD--VPSFLVSDS-KGHLDSPSLSSFYMFFTMIILLQILIPISLYVSVELVKIGQIFFILTDVDLYDEETDSQVQCRSLNITEDLGQIEYIFSDKTGTLTENKMVFRRCSIMGKDYPHKENGKDLSHFIHTFKNAVTQFQKVILYYRNIALCRKPTPKHNVSTSMLDSGDGVLGVVVIAFLHHQETQVIPDEKLLQQISRSERSSSGISDPYMDFFLALAICNSVVVSMATTQRQRV 556          

Query: 2152 YESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQE-----NTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPL---IRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCG-SDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKG 3945
            YE+ESPDE ALV  A  +G+ LL R PN VT+  P  E  + + VL  L FDSNRKRMS++V+ P T   +++ KGAD A+        +   Q+     +T+ ++D YA+ GLR L            SE H  +  A  +    E+ +++   ++E+++ LLG +GIED LQ+ V DTI +LR AGI VW+LTGDK ETA+NI Y+ +L  E                DL+        S     + E+R+    P      + ++L +DG TL  A+  +++  FL LA++C SV+C R TP+QK+ +V+LV++ L++ TLA+GDGANDV+MIQ+ADVG+GI G EGMQAVMASDFA+T+FK+LK+LLLVHG WC+ +LA   +Y FYK+  Y+ L+FW+QF   FS + MID    + FN+  T  PPI++G+ DKD+ A+ LM  PELYR G     Y    FW+++LDA +QS V + + Y+ +  SD+ I+ FG  +   +L   L+HLGIE + WT  H + I +  +  + + T+ Y+ IC  V C    +PY  +   M   +F+L+C+++ + A+ PR T   ++NS+ P+ L + 
Sbjct:  605 YEAESPDEAALVYAAKTYGFTLLARTPNSVTVRVPSGEE-LVFEVLDTLAFDSNRKRMSVLVRHPITGEYVLYTKGADYAIMELLGTPYAGDGQQKKIAADTQYHLDCYAKDGLRTL------------SEQHISFIWAYGR----EELMMASAVQLETELTLLGATGIEDRLQESVPDTITALREAGIKVWVLTGDKPETALNIGYACRLMEEG---------------DLV-----TCVSILDCTLEEVRRYHEDPRNVDTTQKISLMIDGDTLAIALSPDLQDRFLDLAKRCRSVLCCRVTPLQKSRVVKLVRDKLKVMTLAVGDGANDVNMIQVADVGIGISGQEGMQAVMASDFAITRFKHLKKLLLVHGHWCHTRLANMIIYFFYKNAAYVNLLFWYQFYCGFSGTAMIDYWLMIFFNLFFTSTPPIMFGIMDKDVSAEMLMGVPELYRTGQGSGEYNFRTFWISMLDAFYQSLVCFFVPYLAYQGSDVDIFTFGTPLNTSSLFIILLHLGIEIKSWTVVHWI-IMLGSVALYFIVTLAYSAIC--VTCNPPSNPYWILQNQMADPMFYLICIISTVVALLPRYTFYVLKNSIAPSPLIQA 1171          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKL----LKNLIPML------HGDIEIKEEE-----MSRMKNVK--------DFFLLMGICNTTVVSLNKNEKHPVI 1581
            +  N ++T KY  + FIP+NL+EQFHR AN+YFV + ILNF+P + AF  EVA IP+  ++ +TA+KD  ED+RR+++D+++N+  CLIY+   K ++E++W   R GDFVK+  NET+PAD++LLH++D + +CHIETSNLDGE+NLKQR      NN+ F+PE   N  +  E PN  +  F   +  K           +LLLRGCT+RNTE  IG VVYAG ETK+MLNNN  R+KRSKLER++N DV +CVLLL I+CL  S+G+ +W + + +   +  +   DS    + +P++ +F  F+T +I  Q LIP+ LYV+ E VK+ Q+F I  D+++YD E +  ++ R+ NI EDLGQI+Y+F DKTGTLTEN+M F+R  I G DY  K++  D      T ++         +   +  ++    L+ L P++      H + ++  +E     +SR +           DFFL + ICN+ VVS+   ++  VI
Sbjct:   58 FKPNAIKTNKYTPLFFIPMNLYEQFHRLANVYFVGLAILNFIPVVNAFQPEVALIPICVIMFLTALKDGWEDFRRYQSDKKLNNMPCLIYT---KHYIERRWKDVRVGDFVKVVCNETVPADLLLLHTSDPNNVCHIETSNLDGETNLKQR------NNDVFEPESF-NCTVVCEKPNNNLNHFKCFVE-KPDKEKTGAGIESLLLRGCTVRNTEHAIGFVVYAGHETKSMLNNNGPRYKRSKLERRLNVDVFFCVLLLFIMCLIGSLGHYLW-LKNLSD--VPSFLVSDS-KGHLDSPSLSSFYMFFTMIILLQILIPISLYVSVELVKIGQIFFILTDVDLYDEETDSQVQCRSLNITEDLGQIEYIFSDKTGTLTENKMVFRRCSIMGKDYPHKENGKDLSHFIHTFKNAVTQFQKVILYYRNSNRVICCCLRKLSPLVVIAFLHHQETQVIPDEKLLQQISRSERSSSGISDPYMDFFLALAICNSVVVSMATTQRQRVI 546          

Query:  139 YANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVV--MMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWT-----VTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKD--------DETDGQSDKVTMRSEFGD-----------TDDKKMNDDHGKKLLKNLIPMLH-------------GDIEIKEEEMSRMKN-VKDFFLLMGICNTTVVSLNKNEKHPV 1578
            +  N ++T KY  + FIP+NL+EQFHR AN+YFV + ILNF+P + AF  EVA IP+  ++ +TA+KD  ED+RR+++D+++N+  CLIYS   K ++E++W   R GDFVK+  NET+PAD++LLH++D + +CHIETSNLDGE+NLKQR  +  +  +N+ F+PE   N  +  E PN  +  F     FK           +LLLRGCT+RNTE  IG VVYAG ETK+MLNNN  R+KRSKLER++N DV +CVLLL I+CL  S+G+ +W      V SF           DS    + +P++ +F  F+T +I  Q LIP+ LYV+ E VK+ Q+F I  D+++YD E +  ++ R+ NI EDLGQI+Y+F DKTGTLTEN+M F+R  I G DY  K+        +ET+ + + +  +S                D  +    H  K+  NLI  LH               I   E   S + +   DFFL + ICN+ VVS+   ++  V
Sbjct:   47 FKPNAIKTNKYTPLFFIPMNLYEQFHRLANVYFVGLAILNFIPVVNAFQPEVALIPICVIMFLTALKDGWEDFRRYQSDKKLNNMPCLIYSRTAKHYIERRWKDVRVGDFVKVVCNETVPADLLLLHTSDPNNVCHIETSNLDGETNLKQRNALPGLCTSNDVFEPESF-NCTVVCEKPNNNLNHFKC---FKPDKEKTGAGIESLLLRGCTVRNTEHAIGFVVYAGHETKSMLNNNGPRYKRSKLERRLNVDVFFCVLLLFIMCLIGSLGHYLWLKNLSDVPSFLVS--------DS-KGHLDSPSLSSFYMFFTMIILLQILIPISLYVSVELVKIGQIFFILTDVDLYDEETDSQVQCRSLNITEDLGQIEYIFSDKTGTLTENKMVFRRCSIMGKDYPHKENANRLALLEETESEENVIFSQSTLSSQASRYDEDSSPVDTHRHGSRHRSKMAVNLIAFLHHQETQVIPDEKLLQQISRSERSSSGISDPYMDFFLALAICNSVVVSMATTQRQRV 553          

Query:   46 MGNLIPKKNGEEQCRKIYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVIXXXXXXXXXXXXXXXXXAGEGVMNKAASISSFSAKNIFTKSGKVSMKNSDNTEIESKVHDVLFDRNDHSLELLNFKRNDSALPDFDDIHIRITDTNQKDYVQTPNKSRKVKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSDINTEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLGKGSNLYFDYEPELVDVRNPSTIIGSVLGRPSIVDLTKISSEYGIPNTPVRSGSSKPQLLAQKSCGSFSKTHQNFSKHKRVKSYDENKCNHCNNHLVIDQPNVSPIHHEVTSFLTGNRHSQSQCDAHGLQXXXXXXXXXXXXXXXLSIDNDG 4422
            MGNLIPKKNGEEQCRKIYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDF+KLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVLLLIILCLSCSIGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVIKTKKFDLRKQLKKRLLLAGEGVMNKAASISSFSAKNIFTKSGKVSMKNSDNTEIESKVHDVLFDRNDHSLELLNFKRNDSALPDFDDIHIRITDTNQKDYVQTPNKSRKVKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSDINTEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVG+GIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYG+WDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLI EEKLGKGSNLYFDYEPELVDVRNPSTIIGSVLGRPSIVDLTKISSEYGIPNTPVRSGSSKPQLLAQKSCGSFSKTHQNFSKHKRVKSYDENKCNHCNNHLVIDQPNVSPIHHEVTSFLTGNRHSQSQCDAHGLQSSAASPVIAAIPTSSLSIDNDG
Sbjct:    1 MGNLIPKKNGEEQCRKIYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFIKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVLLLIILCLSCSIGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVIKTKKFDLRKQLKKRLLLAGEGVMNKAASISSFSAKNIFTKSGKVSMKNSDNTEIESKVHDVLFDRNDHSLELLNFKRNDSALPDFDDIHIRITDTNQKDYVQTPNKSRKVKSVLDFRSGDNMYADTESIDNINQTDLKTNKKSVHIELSYIADTYSDINTEGDRNNSGIDSFKNDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAMEDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGIGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGIWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIPEEKLGKGSNLYFDYEPELVDVRNPSTIIGSVLGRPSIVDLTKISSEYGIPNTPVRSGSSKPQLLAQKSCGSFSKTHQNFSKHKRVKSYDENKCNHCNNHLVIDQPNVSPIHHEVTSFLTGNRHSQSQCDAHGLQSSAASPVIAAIPTSSLSIDNDG 1459          

Query: 2101 NDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIK---------SNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAM-EDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVV-CGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKL 3966
            N    KCP  D  L   YESESPDE AL KTAC  G KLLQRGP FV IW    ++      L + PFDSNRKRMS+I+  P T  I ++CKGAD+ +    SK+ S    +   + M+ Y++ GLR L++ +R +S+  F EW+ R++  EQ L  +E ELL+L  E+E DM+LLG +GIED LQ+ V + +E+LR+AGI +W+LTGDK ETAINIAYS KLF+ENQ +  L+ +++E   D I++F   I          S Y N + E               L ++G T++  + ED +   FL LA  C SVVC R+TP +KA IV +VK NL+++TLAIGDGANDV+MIQ A VG+GIGG EGMQAVMASDFA+TKFKYL+RLLLVHG  CY++LAR +LYMFYKD+I +L+ FWFQ  N FS S+MID ++Q+LFN+TMTGLPP+I G+WDKD  +  L RNP++Y++GI+ KSY+P  FW NI+D+IWQS VI+ + Y+ +  +++ + EFG +     LI    ++ +E+RFW+ FH L    S ++AW     +   +C  +V C +D+PY  +   M++   +L+  +    A+FPR+ + +   +  P+++Y+ L R + L
Sbjct:  386 NVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCIFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYE-------------YGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNL 1005          

Query:  706 FKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVI 1581
            F+  +  ITL+K+NL+LRGC LRNT+ V GIV+YAG ETK++LNNN   FKRSKLE+QIN+DVIWC+ +LIILC++CSIG+VIW         + ++ F +     ++N ++Q F+ FWT +I +Q +IPLPLYVT E VK+HQ+FHI +DLE+YD++ +K  +VRA NI EDLGQIQY+FCDKTGTLTEN MEFKRA I   D+   DD T+                    +D     +L  ++   H +IEI  +E   M  +++F L + +CNTT+VS NKNE   V+
Sbjct:   22 FEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVIWCIGILIILCIACSIGHVIWMKDFSNVSTVVFFSFSNE---NLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFY--DDATES----------------ALTSDSQPISVLAKMLKKCHRNIEI--DENLDMSIIEEFVLALAVCNTTMVSENKNESKIVV 290          

Query: 2101 NDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIK---------SNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAM-EDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVV-CGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKL 3966
            N    KCP  D  L   YESESPDE AL KTAC  G KLLQRGP FV IW    ++      L + PFDSNRKRMS+I+  P T  I ++CKGAD+ +    SK+ S    +   + M+ Y++ GLR L++ +R +S+  F EW+ R++  EQ L  +E ELL+L  E+E DM+LLG +GIED LQ+ V + +E+LR+AGI +W+LTGDK ETAINIAYS KLF+ENQ +  L+ +++E   D I++F   I          S Y N + E               L ++G T++  + ED +   FL LA  C SVVC R+TP +KA IV +VK NL+++TLAIGDGANDV+MIQ A VG+GIGG EGMQAVMASDFA+TKFKYL+RLLLVHG  CY++LAR +LYMFYKD+I +L+ FWFQ  N FS S+MID ++Q+LFN+TMTGLPP+I G+WDKD  +  L RNP++Y++GI+ KSY+P  FW NI+D+IWQS VI+ + Y+ +  +++ + EFG +     LI    ++ +E+RFW+ FH L    S ++AW     +   +C  +V C +D+PY  +   M++   +L+  +    A+FPR+ + +   +  P+++Y+ L R + L
Sbjct:  412 NVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCIFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYE-------------YGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNL 1031          

Query:  706 FKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVI 1581
            F+  +  ITL+K+NL+LRGC LRNT+ V GIV+YAG ETK++LNNN   FKRSKLE+QIN+DVIWC+ +LIILC++CSIG+VIW         + ++ F +     ++N ++Q F+ FWT +I +Q +IPLPLYVT E VK+HQ+FHI +DLE+YD++ +K  +VRA NI EDLGQIQY+FCDKTGTLTEN MEFKRA I   D+   DD T+                    +D     +L  ++   H +IEI  +E   M  +++F L + +CNTT+VS NKNE   V+
Sbjct:   48 FEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVIWCIGILIILCIACSIGHVIWMKDFSNVSTVVFFSFSNE---NLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFY--DDATES----------------ALTSDSQPISVLAKMLKKCHRNIEI--DENLDMSIIEEFVLALAVCNTTMVSENKNESKIVV 316          

Query: 2125 ISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF----GNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAM-EDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFH--------GLGIFIS-FILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLG-----KGSNLYFDYEPELVDVRNPSTIIGSV 4047
            +++++L     SESPDE ALV+    +G+ L QR  + + IWN    + + Y +L+ LPFDS RK MS+IVK   T  I + CKGADS MF     N  KD   I+Q  TK  + AYA  GLR LVMG+R+++++ + +W +   + E  L NNE E+  L   IES++ L+G  G+ED LQ+ V + +E  + AGI +WILTGDK+ETAI+IAYS +LFS+N+ + E+S  S+ +  +++ +   +I+ +  N     R+   +    K+  L +DG +L+  +  DE+K +FLH+A  C  VVC R TPIQK E+V LVK+   ++TLAIGDGANDV+MIQ AD+G+G+ G EG QA +ASDFA+TKFKYLKRL+LVHG   Y+KLAR +L MFYK+ I  L+MF++Q  + FS S  ID +TQ++F++  TGLPPII+GVWDKD   + L+ NP++Y  GIN K Y+P  FW  ILD++WQS VI+ +  + + +++I + EFG I  +C +I    H+ IE+R W+ FH        G+G ++  FIL  L   ++         C +D+PY  +   M R   +L+  ++   ++FPRL I         ++ Y+   R  KLG        +    ++P + D +N    +G++
Sbjct:  555 LTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQ--TKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVEDNLINNESEIKELYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKEISCESESEIINVMSQIREDIEKSLFNSK---RENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGEVVYLVKKYYEVRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLL--------DCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNL 1201          

Query:   94 IYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVM-MENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRK---NNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVS-LNKNEKHPV 1578
            IYPS       ++ K  NN +RT KY    FI +NLFEQF R++N++F+F +ILNF+PE+ AF +  A IP++F+L VT IKD VED RR+ +D+ VN+   L Y     +F   KW     GD +KL + E IPAD+++ +S+D SG+C IET ++DGE+ LKQR V+  ++NN T   E+  N + EVE  N++IYKFNG IF     IG +++     NL+LR   LRNT EV GIV+YAG +TK  +NN   RFKRS LE Q+N D++ C+ +LII+C+   IG   + +  F +  I+   F  S  TVI +  +Q F+ FWT +I +Q++IP+ LY+T E VK HQ+ HI  DL +YD   +K ++V+A+NI EDLGQI+ +FCDKTGTLT+N M F+ A I G +Y  K +E D       +R    + +++  N+ H  +LL                            LL  ICNTT+++  N+ EK  V
Sbjct:   17 IYPSNFYIPLTDESKKLNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNLTNLEEVFKNYYFEVEASNKQIYKFNGKIF--DHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFY-LRGFNK--IQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY--KTEEND-------LRLCCDNENEELHNNPHILQLL----------------------------LLSAICNTTIIAKSNQREKKLV 474          

Query: 2125 ISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMF----GNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRV------------------------ISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIKSNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAM-EDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGVGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGVWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFH--------GLGIFIS-FILAWLVFTMIYTVICGKVVCGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGLIREEKLG-----KGSNLYFDYEPELVDVRNPSTIIGSV 4047
            +++++L     SESPDE ALV+    +G+ L QR  + + IWN    + + Y +L+ LPFDS RK MS+IVK   T  I + CKGADS MF     N  KD   I+Q  TK  + AYA  GLR LVMG+RV                        ++++ + +W +   + E  L NNE E+  L   IES++ L+G  G+ED LQ+ V + +E  + AGI +WILTGDK+ETAI+IAYS +LFS+N+ + E+S  S+ +  +++ +   +I+ +  N     R+   +    K+  L +DG +L+  +  DE+K +FLH+A  C  VVC R TPIQK E+V LVK+   ++TLAIGDGANDV+MIQ AD+G+G+ G EG QA +ASDFA+TKFKYLKRL+LVHG   Y+KLAR +L MFYK+ I  L+MF++Q  + FS S  ID +TQ++F++  TGLPPII+GVWDKD   + L+ NP++Y  GIN K Y+P  FW  ILD++WQS VI+ +  + + +++I + EFG I  +C +I    H+ IE+R W+ FH        G+G ++  FIL  L   ++         C +D+PY  +   M R   +L+  ++   ++FPRL I         ++ Y+   R  KLG        +    ++P + D +N    +G++
Sbjct:  555 LTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQ--TKADIYAYASNGLRTLVMGKRVSNLHKINVFNAIIEGKSNNNIIWILNENEYKKWEETLSKVEDNLINNESEIKELYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKEISCESESEIINVMSQIREDIEKSLFNSK---RENNEKTCKHKEFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGEVVYLVKKYYEVRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLL--------DCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNL 1225          

Query:   94 IYPSTSTNSNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFVKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVM-MENNNTFKPEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRK---NNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVXXXXXXXXXXXXGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVS-LNKNEKHPV 1578
            IYPS       ++ K  NN +RT KY    FI +NLFEQF R++N++F+F +ILNF+PE+ AF +  A IP++F+L VT IKD VED RR+ +D+ VN+   L Y     +F   KW     GD +KL + E IPAD+++ +S+D SG+C IET ++DGE+ LKQR V+  ++NN T   E+  N + EVE  N++IYKFNG IF     IG +++     NL+LR   LRNT EV GIV+YAG +TK  +NN   RFKRS LE Q+N D++ C+ +LII+C+   IG   + +  F +  I+   F  S  TVI +  +Q F+ FWT +I +Q++IP+ LY+T E VK HQ+ HI  DL +YD   +K ++V+A+NI EDLGQI+ +FCDKTGTLT+N M F+ A I G +Y  K +E D       +R    + +++  N+ H  +LL                            LL  ICNTT+++  N+ EK  V
Sbjct:   17 IYPSNFYIPLTDESKKLNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNLTNLEEVFKNYYFEVEASNKQIYKFNGKIF--DHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFY-LRGFNK--IQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNY--KTEEND-------LRLCCDNENEELHNNPHILQLL----------------------------LLSAICNTTIIAKSNQREKKLV 474