Dynein light chain

Overview
NameDynein light chain
Smed IDSMED30026942
Length (bp)721
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Dynein light chain (SMED30026942) t-SNE clustered cells

Violin plots show distribution of expression levels for Dynein light chain (SMED30026942) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dynein light chain (SMED30026942) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dynein light chain (SMED30026942) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30026942

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30026942SMESG000052937.1 SMESG000027765.1 SmedASXL_003785SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30026942SMESG000052937.1 SMESG000027765.1 dd_Smed_v4_2487_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30026942SMESG000052937.1 SMESG000027765.1 dd_Smed_v4_2487_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30026942SMESG000052937.1 SMESG000027765.1 dd_Smed_v4_2487_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30026942SMESG000052937.1 SMESG000027765.1 dd_Smed_v4_2487_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30026942SMESG000052937.1 SMESG000027765.1 dd_Smed_v4_2487_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
parapharyngeal regionSMED30026942SMESG000052937.1 SMESG000027765.1 dd_Smed_v4_2487_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30026942SMESG000052937.1 SMESG000027765.1 dd_Smed_v4_2487_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30026942SMESG000052937.1 SMESG000027765.1 dd_Smed_v4_2487_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026942SMESG000055315.1 SMESG000054374.1 Contig137GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026942SMESG000052937.1 SMESG000027765.1 Contig137GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30026942SMESG000052937.1 SMESG000027765.1 dd_Smed_v6_2487_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30026942SMESG000052937.1 SMESG000027765.1 dd_Smed_v4_2487_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DNAL4 (dynein axonemal light chain 4 [Source:HGNC Symbol;Acc:HGNC:2955])

HSP 1 Score: 157.532 bits (397), Expect = 8.109e-49
Identity = 67/91 (73.63%), Postives = 83/91 (91.21%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+ T+PLVR+SDM EE+R E MEL VTACEKFS++NE+AAKM+KETMDKKFG++WHV+IGEG+GFEITHE KNLLY+YFGG +A+ +WKCS
Sbjct:   15 RLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS 105
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 69.707 bits (169), Expect = 5.347e-15
Identity = 33/83 (39.76%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +++E    A EK++   + AA + KE  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 69.707 bits (169), Expect = 5.347e-15
Identity = 33/83 (39.76%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +++E    A EK++   + AA + KE  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 69.707 bits (169), Expect = 5.347e-15
Identity = 33/83 (39.76%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +++E    A EK++   + AA + KE  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Human
Match: DYNLL1 (dynein light chain LC8-type 1 [Source:HGNC Symbol;Acc:HGNC:15476])

HSP 1 Score: 69.707 bits (169), Expect = 5.347e-15
Identity = 33/83 (39.76%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +++E    A EK++   + AA + KE  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 67.3958 bits (163), Expect = 1.277e-14
Identity = 30/83 (36.14%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMS++++ +A++    A EK++   + AA  +K+  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSDDMQQDAIDCATQALEKYNIEKDIAA-YIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 67.3958 bits (163), Expect = 1.277e-14
Identity = 30/83 (36.14%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMS++++ +A++    A EK++   + AA  +K+  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSDDMQQDAIDCATQALEKYNIEKDIAA-YIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-1 (Dynein light chain 1, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q22799])

HSP 1 Score: 67.3958 bits (163), Expect = 1.277e-14
Identity = 30/83 (36.14%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMS++++ +A++    A EK++   + AA  +K+  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSDDMQQDAIDCATQALEKYNIEKDIAA-YIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Celegans
Match: dlc-2 (Probable dynein light chain 2, cytoplasmic [Source:UniProtKB/Swiss-Prot;Acc:Q21557])

HSP 1 Score: 48.9062 bits (115), Expect = 8.343e-8
Identity = 24/83 (28.92%), Postives = 49/83 (59.04%), Query Frame = 2 
Query:  113 VRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKC 361
            V+ +DM +  R   + ++  A ++  + ++  A  VKE +DKKFGA WHVI G+ +G  +++E  + + +     + ++++KC
Sbjct:    8 VKETDMEDPQRDMVISVVREA-QRLYNIDKDVAAFVKEELDKKFGATWHVICGKCFGSRVSYEMGHFILLKC-NKVNVMIYKC 88
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: CG8407 (gene:FBgn0033687 transcript:FBtr0087985)

HSP 1 Score: 140.969 bits (354), Expect = 1.227e-42
Identity = 59/90 (65.56%), Postives = 81/90 (90.00%), Query Frame = 2 
Query:   95 VHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            VH YPLV+++DM+EE+R EA+EL +TACEK+SS+ E AAK++KE MDKKFG  WHV++GEG+GFE+++ET+N+LY++F GN+AIVLWKCS
Sbjct:   15 VHVYPLVKHTDMNEEMRIEAIELSITACEKYSSNYEHAAKIIKENMDKKFGIYWHVVVGEGFGFEVSYETENILYLFFAGNLAIVLWKCS 104
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: CG8407 (gene:FBgn0033687 transcript:FBtr0301127)

HSP 1 Score: 140.969 bits (354), Expect = 1.227e-42
Identity = 59/90 (65.56%), Postives = 81/90 (90.00%), Query Frame = 2 
Query:   95 VHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            VH YPLV+++DM+EE+R EA+EL +TACEK+SS+ E AAK++KE MDKKFG  WHV++GEG+GFE+++ET+N+LY++F GN+AIVLWKCS
Sbjct:   15 VHVYPLVKHTDMNEEMRIEAIELSITACEKYSSNYEHAAKIIKENMDKKFGIYWHVVVGEGFGFEVSYETENILYLFFAGNLAIVLWKCS 104
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: Cdlc2 (gene:FBgn0026141 transcript:FBtr0077924)

HSP 1 Score: 68.5514 bits (166), Expect = 5.719e-15
Identity = 31/83 (37.35%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +A++    A EK++   + AA  +K+  DKK+   WH I+G  +G  +THET++ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDAVDCATQALEKYNIEKDIAA-FIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: Cdlc2 (gene:FBgn0026141 transcript:FBtr0305553)

HSP 1 Score: 68.5514 bits (166), Expect = 5.719e-15
Identity = 31/83 (37.35%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +A++    A EK++   + AA  +K+  DKK+   WH I+G  +G  +THET++ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDAVDCATQALEKYNIEKDIAA-FIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Fly
Match: Cdlc2 (gene:FBgn0026141 transcript:FBtr0077925)

HSP 1 Score: 68.5514 bits (166), Expect = 5.719e-15
Identity = 31/83 (37.35%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +A++    A EK++   + AA  +K+  DKK+   WH I+G  +G  +THET++ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDAVDCATQALEKYNIEKDIAA-FIKKEFDKKYNPTWHCIVGRNFGSYVTHETRHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dnal4b (dynein, axonemal, light chain 4b [Source:ZFIN;Acc:ZDB-GENE-050208-510])

HSP 1 Score: 154.836 bits (390), Expect = 6.150e-48
Identity = 63/91 (69.23%), Postives = 84/91 (92.31%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+H +PL+R++DM EE+R E MEL VTACEKF+++NE+AAKM+KE+MDKKFG++WHV+IGEG+GFEITHE KNLLYM+FGG++A+ +WKCS
Sbjct:   16 RLHNFPLIRHTDMPEEMRVETMELCVTACEKFATNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEITHEVKNLLYMFFGGSLAVCVWKCS 106
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dnal4b (dynein, axonemal, light chain 4b [Source:ZFIN;Acc:ZDB-GENE-050208-510])

HSP 1 Score: 154.836 bits (390), Expect = 6.286e-48
Identity = 63/91 (69.23%), Postives = 84/91 (92.31%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+H +PL+R++DM EE+R E MEL VTACEKF+++NE+AAKM+KE+MDKKFG++WHV+IGEG+GFEITHE KNLLYM+FGG++A+ +WKCS
Sbjct:   16 RLHNFPLIRHTDMPEEMRVETMELCVTACEKFATNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEITHEVKNLLYMFFGGSLAVCVWKCS 106
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dnal4b (dynein, axonemal, light chain 4b [Source:ZFIN;Acc:ZDB-GENE-050208-510])

HSP 1 Score: 154.836 bits (390), Expect = 6.286e-48
Identity = 63/91 (69.23%), Postives = 84/91 (92.31%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+H +PL+R++DM EE+R E MEL VTACEKF+++NE+AAKM+KE+MDKKFG++WHV+IGEG+GFEITHE KNLLYM+FGG++A+ +WKCS
Sbjct:   16 RLHNFPLIRHTDMPEEMRVETMELCVTACEKFATNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEITHEVKNLLYMFFGGSLAVCVWKCS 106
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dnal4b (dynein, axonemal, light chain 4b [Source:ZFIN;Acc:ZDB-GENE-050208-510])

HSP 1 Score: 154.836 bits (390), Expect = 6.286e-48
Identity = 63/91 (69.23%), Postives = 84/91 (92.31%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+H +PL+R++DM EE+R E MEL VTACEKF+++NE+AAKM+KE+MDKKFG++WHV+IGEG+GFEITHE KNLLYM+FGG++A+ +WKCS
Sbjct:   16 RLHNFPLIRHTDMPEEMRVETMELCVTACEKFATNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEITHEVKNLLYMFFGGSLAVCVWKCS 106
[Close]
BLAST of Dynein light chain vs. Ensembl Zebrafish
Match: dnal4a (dynein, axonemal, light chain 4a [Source:ZFIN;Acc:ZDB-GENE-040801-122])

HSP 1 Score: 152.525 bits (384), Expect = 4.308e-47
Identity = 61/91 (67.03%), Postives = 84/91 (92.31%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+ ++PL+R++DM EE+R E MEL VTACEKF+S+NE+AAKM+KE+MDKKFG++WHV+IGEG+GFE+THE +NLLYM+FGG++A+ +WKCS
Sbjct:   16 RLQSFPLIRHTDMPEEMRVETMELCVTACEKFASNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEVTHEVRNLLYMFFGGSLAVCVWKCS 106
[Close]
BLAST of Dynein light chain vs. Ensembl Xenopus
Match: rnf181 (ring finger protein 181 [Source:Xenbase;Acc:XB-GENE-964051])

HSP 1 Score: 157.918 bits (398), Expect = 5.237e-49
Identity = 66/91 (72.53%), Postives = 85/91 (93.41%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+H++PL+R++DM EE+R E MEL VTACEKF+S+NE+AAKM+KETMDKKFG++WHV+IGEG+GFEITHE KNLLYM+FGG++AI +WKCS
Sbjct:   16 RMHSFPLIRHTDMPEEMRVETMELCVTACEKFASNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYMFFGGSLAICVWKCS 106
[Close]
BLAST of Dynein light chain vs. Ensembl Xenopus
Match: dynll1 (dynein light chain LC8-type 1 [Source:NCBI gene;Acc:448652])

HSP 1 Score: 70.8626 bits (172), Expect = 1.688e-15
Identity = 33/83 (39.76%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +A++    A EKF+   + AA  +K+  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDAVDCATQALEKFNIEKDIAA-FIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Xenopus
Match: dynll2 (dynein light chain LC8-type 2 [Source:NCBI gene;Acc:100038056])

HSP 1 Score: 67.781 bits (164), Expect = 2.243e-14
Identity = 31/83 (37.35%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSE+++ +A++    A EK++   + AA  +K+  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAA-YIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dnal4 (dynein, axonemal, light chain 4 [Source:MGI Symbol;Acc:MGI:1859217])

HSP 1 Score: 157.147 bits (396), Expect = 6.343e-49
Identity = 67/91 (73.63%), Postives = 83/91 (91.21%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+ T+PLVR+SDM EE+R E MEL VTACEKFS++NE+AAKM+KETMDKKFG++WHV+IGEG+GFEITHE KNLLY+YFGG +A+ +WKCS
Sbjct:   15 RLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS 105
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dnal4 (dynein, axonemal, light chain 4 [Source:MGI Symbol;Acc:MGI:1859217])

HSP 1 Score: 157.147 bits (396), Expect = 6.343e-49
Identity = 67/91 (73.63%), Postives = 83/91 (91.21%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+ T+PLVR+SDM EE+R E MEL VTACEKFS++NE+AAKM+KETMDKKFG++WHV+IGEG+GFEITHE KNLLY+YFGG +A+ +WKCS
Sbjct:   15 RLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS 105
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dnal4 (dynein, axonemal, light chain 4 [Source:MGI Symbol;Acc:MGI:1859217])

HSP 1 Score: 125.561 bits (314), Expect = 4.663e-36
Identity = 53/73 (72.60%), Postives = 67/73 (91.78%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKN 310
            R+ T+PLVR+SDM EE+R E MEL VTACEKFS++NE+AAKM+KETMDKKFG++WHV+IGEG+GFEITHE ++
Sbjct:   15 RLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEPQS 87
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dnal4 (dynein, axonemal, light chain 4 [Source:MGI Symbol;Acc:MGI:1859217])

HSP 1 Score: 100.523 bits (249), Expect = 3.680e-27
Identity = 47/91 (51.65%), Postives = 59/91 (64.84%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+ T+PLVR                            +AAKM+KETMDKKFG++WHV+IGEG+GFEITHE KNLLY+YFGG +A+ +WKCS
Sbjct:   15 RLQTFPLVR----------------------------SAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS 77
[Close]
BLAST of Dynein light chain vs. Ensembl Mouse
Match: Dynll1 (dynein light chain LC8-type 1 [Source:MGI Symbol;Acc:MGI:1861457])

HSP 1 Score: 69.707 bits (169), Expect = 3.671e-15
Identity = 33/83 (39.76%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +++E    A EK++   + AA + KE  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|A4F4L4|DNAL4_PIG (Dynein light chain 4, axonemal OS=Sus scrofa OX=9823 GN=DNAL4 PE=3 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 3.894e-48
Identity = 67/91 (73.63%), Postives = 83/91 (91.21%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+ T+PLVR+SDM EE+R E MEL VTACEKFS++NE+AAKM+KETMDKKFG++WHV+IGEG+GFEITHE KNLLY+YFGG +A+ +WKCS
Sbjct:   15 RLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS 105
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|O96015|DNAL4_HUMAN (Dynein light chain 4, axonemal OS=Homo sapiens OX=9606 GN=DNAL4 PE=1 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 3.894e-48
Identity = 67/91 (73.63%), Postives = 83/91 (91.21%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+ T+PLVR+SDM EE+R E MEL VTACEKFS++NE+AAKM+KETMDKKFG++WHV+IGEG+GFEITHE KNLLY+YFGG +A+ +WKCS
Sbjct:   15 RLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS 105
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q32KN5|DNAL4_BOVIN (Dynein light chain 4, axonemal OS=Bos taurus OX=9913 GN=DNAL4 PE=3 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 3.894e-48
Identity = 67/91 (73.63%), Postives = 83/91 (91.21%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+ T+PLVR+SDM EE+R E MEL VTACEKFS++NE+AAKM+KETMDKKFG++WHV+IGEG+GFEITHE KNLLY+YFGG +A+ +WKCS
Sbjct:   15 RLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS 105
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|Q9DCM4|DNAL4_MOUSE (Dynein light chain 4, axonemal OS=Mus musculus OX=10090 GN=Dnal4 PE=3 SV=2)

HSP 1 Score: 157.147 bits (396), Expect = 4.437e-48
Identity = 67/91 (73.63%), Postives = 83/91 (91.21%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+ T+PLVR+SDM EE+R E MEL VTACEKFS++NE+AAKM+KETMDKKFG++WHV+IGEG+GFEITHE KNLLY+YFGG +A+ +WKCS
Sbjct:   15 RLQTFPLVRHSDMPEEMRVETMELCVTACEKFSNNNESAAKMIKETMDKKFGSSWHVVIGEGFGFEITHEVKNLLYLYFGGTLAVCVWKCS 105
[Close]
BLAST of Dynein light chain vs. UniProt/SwissProt
Match: sp|P63170|DYL1_RAT (Dynein light chain 1, cytoplasmic OS=Rattus norvegicus OX=10116 GN=Dynll1 PE=1 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 2.568e-14
Identity = 33/83 (39.76%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +++E    A EK++   + AA + KE  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A433TQB4 (Dynein light chain OS=Elysia chlorotica OX=188477 GN=EGW08_008548 PE=3 SV=1)

HSP 1 Score: 171.014 bits (432), Expect = 5.949e-51
Identity = 73/91 (80.22%), Postives = 87/91 (95.60%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            RVHTYPL+R+SDM++E++TEAMEL VTACEKFSS+NE AAKM+K+TMDKKFGA+WH ++GEGYGFEITHE KNLLYM+FGGNMAI+LWKCS
Sbjct:   16 RVHTYPLIRHSDMNDEMKTEAMELCVTACEKFSSNNETAAKMIKDTMDKKFGASWHAVVGEGYGFEITHEVKNLLYMFFGGNMAIILWKCS 106
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: K1QHD3 (Dynein light chain OS=Crassostrea gigas OX=29159 GN=CGI_10004520 PE=3 SV=1)

HSP 1 Score: 169.088 bits (427), Expect = 3.054e-50
Identity = 72/91 (79.12%), Postives = 87/91 (95.60%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            RVHTYPL+R+SDM++E++TEAMEL VTACEKFSS+NE AA+M+KETMDKKFGA+WH ++GEGYGFEITHE KNLLYM+FGGNMAI++WKCS
Sbjct:   15 RVHTYPLIRHSDMNDEMKTEAMELCVTACEKFSSNNENAARMIKETMDKKFGASWHAVVGEGYGFEITHEVKNLLYMFFGGNMAIIVWKCS 105
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A267F3Z6 (Dynein light chain OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig002549g1 PE=3 SV=1)

HSP 1 Score: 169.088 bits (427), Expect = 3.230e-50
Identity = 72/91 (79.12%), Postives = 87/91 (95.60%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            RVHTYPLVRYSDM+EE+RTEAMEL VTACEKF+S+NE+AA+M+K++MDKKFG AWH ++GEGYGFEITHE KNL+YM+FGGNMAI+LWKC+
Sbjct:   14 RVHTYPLVRYSDMNEEMRTEAMELCVTACEKFASNNESAARMIKDSMDKKFGPAWHAVVGEGYGFEITHELKNLMYMFFGGNMAIILWKCA 104
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: A0A210QKU2 (Dynein light chain OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT05058 PE=3 SV=1)

HSP 1 Score: 168.703 bits (426), Expect = 4.189e-50
Identity = 73/91 (80.22%), Postives = 87/91 (95.60%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            RVHTYPL+R+SDM++E++TEAMEL VTACEKFSS+NE AA+M+KETMDKKFGA+WH I+GEGYGFEITHE KNLLYM+FGGNMAI++WKCS
Sbjct:   15 RVHTYPLIRHSDMNDEMKTEAMELCVTACEKFSSNNETAARMIKETMDKKFGASWHAIVGEGYGFEITHEVKNLLYMFFGGNMAIMIWKCS 105
[Close]
BLAST of Dynein light chain vs. TrEMBL
Match: V3YVH6 (Dynein light chain OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_204935 PE=3 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 7.605e-50
Identity = 72/91 (79.12%), Postives = 87/91 (95.60%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            RVHTYPL+R+SDM++E++TEAMEL VTACEKFS++NE AAKM+KETMDKKFGA+WH ++GEGYGFEITHE KNLLYM+FGGNMAI++WKCS
Sbjct:   17 RVHTYPLIRHSDMNDEMKTEAMELCVTACEKFSANNENAAKMIKETMDKKFGASWHAVVGEGYGFEITHEVKNLLYMFFGGNMAIMIWKCS 107
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dnal4b (dynein axonemal light chain 4 [Source:NCBI gene;Acc:103029781])

HSP 1 Score: 154.451 bits (389), Expect = 6.339e-48
Identity = 62/91 (68.13%), Postives = 85/91 (93.41%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+H++PL+R++DM EE+R E MEL VTACEKF+++NE+AAKM+KE+MDKKFG++WHV+IGEG+GFE+THE KNLLYM+FGG++A+ +WKCS
Sbjct:   16 RLHSFPLIRHTDMPEEMRVETMELCVTACEKFATNNESAAKMIKESMDKKFGSSWHVVIGEGFGFEVTHEVKNLLYMFFGGSLAVCVWKCS 106
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dynll1 (dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:ZDB-GENE-040426-1961])

HSP 1 Score: 68.9366 bits (167), Expect = 1.071e-14
Identity = 31/82 (37.80%), Postives = 50/82 (60.98%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLW 355
            +++ +DMSEE++ +A+E    A EK++   + AA + KE  DKK+   WH I+G  +G  +THETK+ +Y Y G      +W
Sbjct:    7 VIKNADMSEEMQQDAVECATQALEKYNIEKDIAAYIKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQRNGWAVW 87
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: ENSAMXT00000047143.1 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:103041528])

HSP 1 Score: 67.781 bits (164), Expect = 1.253e-14
Identity = 32/83 (38.55%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSE+++ +A++    A EK++   + AA + KE  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Cavefish
Match: dynll2b (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:103041528])

HSP 1 Score: 67.781 bits (164), Expect = 1.253e-14
Identity = 32/83 (38.55%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSE+++ +A++    A EK++   + AA + KE  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Yeast
Match: DYN2 (Cytoplasmic light chain dynein, microtubule motor protein; required for intracellular transport and cell division; involved in mitotic spindle positioning; forms complex with dynein intermediate chain Pac11p that promotes Dyn1p homodimerization, potentiates motor processivity; Dyn2p-Pac11p complex important for interaction of dynein motor complex with dynactin complex; acts as molecular glue to dimerize, stabilize Nup82-Nsp1-Nup159 complex module of cytoplasmic pore filaments [Source:SGD;Acc:S000002832])

HSP 1 Score: 59.3066 bits (142), Expect = 2.506e-12
Identity = 26/86 (30.23%), Postives = 54/86 (62.79%), Query Frame = 2 
Query:  107 PLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            P+V+ SD++++++ + + +   A +K+    + A   VK+ +D K+G  WHVI+G+ +G  +THE  + +Y Y  G +A +++K +
Sbjct:    9 PIVKASDITDKLKEDILTISKDALDKYQLERDIAG-TVKKQLDVKYGNTWHVIVGKNFGSYVTHEKGHFVYFYI-GPLAFLVFKTA 92
[Close]
BLAST of Dynein light chain vs. Ensembl Nematostella
Match: EDO38557 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCP2])

HSP 1 Score: 158.688 bits (400), Expect = 5.051e-50
Identity = 66/91 (72.53%), Postives = 84/91 (92.31%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+H++PL+RYSDM++E+RTEAMEL VTACEKFS++NE AAKM+KE+MDKKFGA+WH ++GEG+GFEITHE +NLLYM+FGG  AI +WKCS
Sbjct:   20 RLHSFPLIRYSDMNDEMRTEAMELCVTACEKFSNNNETAAKMIKESMDKKFGASWHAVVGEGFGFEITHEVRNLLYMFFGGTTAICIWKCS 110
[Close]
BLAST of Dynein light chain vs. Ensembl Nematostella
Match: EDO44582 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVI5])

HSP 1 Score: 71.633 bits (174), Expect = 1.744e-16
Identity = 33/83 (39.76%), Postives = 56/83 (67.47%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DM+E+++T+A+E    A EKF+   + AA  +K+  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMAEDMQTDAIECATQALEKFNIEKDIAA-FIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: dnal4b (dynein axonemal light chain 4 [Source:NCBI gene;Acc:101161374])

HSP 1 Score: 144.821 bits (364), Expect = 3.264e-44
Identity = 58/91 (63.74%), Postives = 81/91 (89.01%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            R+H +PL+R++DM +E+R E MEL V+ACE F+++NE+AAKM+KE MDKKFG++WHV+IGE +GFE+THE KNLLYM+FGG++A+ +WKCS
Sbjct:   16 RLHNFPLIRHTDMPDEMRIETMELCVSACETFATNNESAAKMIKEHMDKKFGSSWHVVIGESFGFEVTHELKNLLYMFFGGSLAVCVWKCS 106
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: dynll1 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101171417])

HSP 1 Score: 68.9366 bits (167), Expect = 4.827e-15
Identity = 32/83 (38.55%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSE+++ +A+E    A EK++   + AA  +K+  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEDMQQDAVECATQALEKYNIEKDIAA-YIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: ENSORLT00000005747.2 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101162462])

HSP 1 Score: 68.5514 bits (166), Expect = 6.463e-15
Identity = 33/83 (39.76%), Postives = 55/83 (66.27%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMSEE++ +A++    A EK++   + AA + KE  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSEEMQQDAVDCATQAMEKYNIEKDIAAYIKKE-FDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Ensembl Medaka
Match: DYNLL2 (dynein light chain 2, cytoplasmic [Source:NCBI gene;Acc:101174042])

HSP 1 Score: 68.5514 bits (166), Expect = 8.128e-15
Identity = 32/83 (38.55%), Postives = 56/83 (67.47%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ +DMS+E++ +A++  + A EK++   + AA  VK+  DKK+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNADMSDEMQQDAVDCAMQAMEKYNIEKDIAA-YVKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000027765.1 (SMESG000027765.1)

HSP 1 Score: 192.2 bits (487), Expect = 5.672e-63
Identity = 91/91 (100.00%), Postives = 91/91 (100.00%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS
Sbjct:   14 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 104
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000018122.1 (SMESG000018122.1)

HSP 1 Score: 125.946 bits (315), Expect = 7.118e-37
Identity = 56/91 (61.54%), Postives = 70/91 (76.92%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
             V  YPL+R+ DMSEE+R E  E   TACEK++  NE AAKMVKET+D+K G  W V+IGEGYGFE+T++ K L+YMYFGGN AI++WKC 
Sbjct:   17 NVLVYPLIRFCDMSEEVRMECAETCQTACEKYND-NEIAAKMVKETLDQKCGNGWQVVIGEGYGFEVTYDKKCLMYMYFGGNSAILVWKCC 106
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000052937.1 (SMESG000052937.1)

HSP 1 Score: 121.709 bits (304), Expect = 1.133e-35
Identity = 63/91 (69.23%), Postives = 63/91 (69.23%), Query Frame = 2 
Query:   92 RVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 364
            RVHTYPLVR                            AAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS
Sbjct:   14 RVHTYPLVR----------------------------AAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKCS 76
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000024590.1 (SMESG000024590.1)

HSP 1 Score: 72.4034 bits (176), Expect = 1.668e-16
Identity = 35/83 (42.17%), Postives = 56/83 (67.47%), Query Frame = 2 
Query:  110 LVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWK 358
            +++ SDMSEE++ +A+E  V A EK++   + AA + KE  D+K+   WH I+G  +G  +THETK+ +Y Y  G +AI+L+K
Sbjct:    7 VIKNSDMSEEMQQDAIECAVVAMEKYNVEKDIAAYLKKE-FDRKYNPTWHAIVGRNFGSYVTHETKHFIYFYL-GQVAILLFK 87
[Close]
BLAST of Dynein light chain vs. Planmine SMEST
Match: SMESG000055713.1 (SMESG000055713.1)

HSP 1 Score: 72.4034 bits (176), Expect = 2.190e-16
Identity = 33/85 (38.82%), Postives = 58/85 (68.24%), Query Frame = 2 
Query:  107 PLVRYSDMSEEIRTEAMELIVTACEKFSSSNEAAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVLWKC 361
             +++ +DMSEE++ +A+EL   A EK++   + AA + KE  D+K+ ++WH I+G  +G  +THETK+ +Y Y  G +A++L+K 
Sbjct:    6 AVIKNADMSEEMQQDAIELAALAMEKYNVEKDIAAYLKKE-FDRKYNSSWHAIVGRNFGSYVTHETKHFIYFYL-GQVAVLLFKS 88
The following BLAST results are available for this feature:
BLAST of Dynein light chain vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DNAL48.109e-4973.63dynein axonemal light chain 4 [Source:HGNC Symbol;... [more]
DYNLL15.347e-1539.76dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL15.347e-1539.76dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL15.347e-1539.76dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
DYNLL15.347e-1539.76dynein light chain LC8-type 1 [Source:HGNC Symbol;... [more]
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BLAST of Dynein light chain vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
dlc-11.277e-1436.14Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-11.277e-1436.14Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-11.277e-1436.14Dynein light chain 1, cytoplasmic [Source:UniProt... [more]
dlc-28.343e-828.92Probable dynein light chain 2, cytoplasmic [Sourc... [more]
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BLAST of Dynein light chain vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG84071.227e-4265.56gene:FBgn0033687 transcript:FBtr0087985[more]
CG84071.227e-4265.56gene:FBgn0033687 transcript:FBtr0301127[more]
Cdlc25.719e-1537.35gene:FBgn0026141 transcript:FBtr0077924[more]
Cdlc25.719e-1537.35gene:FBgn0026141 transcript:FBtr0305553[more]
Cdlc25.719e-1537.35gene:FBgn0026141 transcript:FBtr0077925[more]
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BLAST of Dynein light chain vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnal4b6.150e-4869.23dynein, axonemal, light chain 4b [Source:ZFIN;Acc:... [more]
dnal4b6.286e-4869.23dynein, axonemal, light chain 4b [Source:ZFIN;Acc:... [more]
dnal4b6.286e-4869.23dynein, axonemal, light chain 4b [Source:ZFIN;Acc:... [more]
dnal4b6.286e-4869.23dynein, axonemal, light chain 4b [Source:ZFIN;Acc:... [more]
dnal4a4.308e-4767.03dynein, axonemal, light chain 4a [Source:ZFIN;Acc:... [more]
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BLAST of Dynein light chain vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
rnf1815.237e-4972.53ring finger protein 181 [Source:Xenbase;Acc:XB-GEN... [more]
dynll11.688e-1539.76dynein light chain LC8-type 1 [Source:NCBI gene;Ac... [more]
dynll22.243e-1437.35dynein light chain LC8-type 2 [Source:NCBI gene;Ac... [more]
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BLAST of Dynein light chain vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dnal46.343e-4973.63dynein, axonemal, light chain 4 [Source:MGI Symbol... [more]
Dnal46.343e-4973.63dynein, axonemal, light chain 4 [Source:MGI Symbol... [more]
Dnal44.663e-3672.60dynein, axonemal, light chain 4 [Source:MGI Symbol... [more]
Dnal43.680e-2751.65dynein, axonemal, light chain 4 [Source:MGI Symbol... [more]
Dynll13.671e-1539.76dynein light chain LC8-type 1 [Source:MGI Symbol;A... [more]
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BLAST of Dynein light chain vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A4F4L4|DNAL4_PIG3.894e-4873.63Dynein light chain 4, axonemal OS=Sus scrofa OX=98... [more]
sp|O96015|DNAL4_HUMAN3.894e-4873.63Dynein light chain 4, axonemal OS=Homo sapiens OX=... [more]
sp|Q32KN5|DNAL4_BOVIN3.894e-4873.63Dynein light chain 4, axonemal OS=Bos taurus OX=99... [more]
sp|Q9DCM4|DNAL4_MOUSE4.437e-4873.63Dynein light chain 4, axonemal OS=Mus musculus OX=... [more]
sp|P63170|DYL1_RAT2.568e-1439.76Dynein light chain 1, cytoplasmic OS=Rattus norveg... [more]
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BLAST of Dynein light chain vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A433TQB45.949e-5180.22Dynein light chain OS=Elysia chlorotica OX=188477 ... [more]
K1QHD33.054e-5079.12Dynein light chain OS=Crassostrea gigas OX=29159 G... [more]
A0A267F3Z63.230e-5079.12Dynein light chain OS=Macrostomum lignano OX=28230... [more]
A0A210QKU24.189e-5080.22Dynein light chain OS=Mizuhopecten yessoensis OX=6... [more]
V3YVH67.605e-5079.12Dynein light chain OS=Lottia gigantea OX=225164 GN... [more]
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BLAST of Dynein light chain vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
dnal4b6.339e-4868.13dynein axonemal light chain 4 [Source:NCBI gene;Ac... [more]
dynll11.071e-1437.80dynein, light chain, LC8-type 1 [Source:ZFIN;Acc:Z... [more]
ENSAMXT00000047143.11.253e-1438.55dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
dynll2b1.253e-1438.55dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
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BLAST of Dynein light chain vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Dynein light chain vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
DYN22.506e-1230.23Cytoplasmic light chain dynein, microtubule motor ... [more]
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BLAST of Dynein light chain vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO385575.051e-5072.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO445821.744e-1639.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Dynein light chain vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
dnal4b3.264e-4463.74dynein axonemal light chain 4 [Source:NCBI gene;Ac... [more]
dynll14.827e-1538.55dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
ENSORLT00000005747.26.463e-1539.76dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
DYNLL28.128e-1538.55dynein light chain 2, cytoplasmic [Source:NCBI gen... [more]
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BLAST of Dynein light chain vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000027765.15.672e-63100.00SMESG000027765.1[more]
SMESG000018122.17.118e-3761.54SMESG000018122.1[more]
SMESG000052937.11.133e-3569.23SMESG000052937.1[more]
SMESG000024590.11.668e-1642.17SMESG000024590.1[more]
SMESG000055713.12.190e-1638.82SMESG000055713.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026942 ID=SMED30026942|Name=Dynein light chain|organism=Schmidtea mediterranea sexual|type=transcript|length=721bp
CTTTAAGATATTTTATAAAGTAACCATAGTGCTGTTATAGCTAATAATTT
AAATGGCCGAAGAAGTTGTCGAAAAGAAGGAAGAAGCAAAAAGAGTTCAT
ACTTATCCATTAGTTAGATACTCCGACATGTCAGAGGAGATTCGCACCGA
AGCAATGGAACTCATTGTGACAGCATGTGAAAAGTTTTCTTCAAGCAACG
AAGCTGCTGCTAAAATGGTCAAGGAAACTATGGACAAAAAGTTTGGAGCT
GCTTGGCATGTCATTATTGGAGAAGGATACGGGTTTGAAATAACTCACGA
AACTAAAAATCTTTTGTATATGTATTTCGGAGGAAATATGGCTATCGTGT
TATGGAAGTGCTCTTAAAATTCTTGAACATTGTAATAGATTTGTAGATTT
TTTCTGATTCTTTTTTATCTATTCTCAACAATATTTTTTATTATGAAATT
TTATTCCAATTTTAATTGGTATATCAGAAAAATACAGTTTGTAATGAGAT
TGACACTTATCCTTGGCAACCAATAAAATTTGTAGTTGGTTGCTATGGGT
GTGTGTGTGTCATTTTTGGATGGTTTTTATTGATTTGATTTTATTCCGCT
TGTGATTTCGACGAATCATTGATATAATTAATTTAAAGTTGAAATTTAAA
TGATAAATTTTTACATATTCTAACAAGTAATTATTATCAATTTAGTTTTG
AAATTTGCAATATTGGTAATG
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protein sequence of SMED30026942-orf-1

>SMED30026942-orf-1 ID=SMED30026942-orf-1|Name=SMED30026942-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=105bp
MAEEVVEKKEEAKRVHTYPLVRYSDMSEEIRTEAMELIVTACEKFSSSNE
AAAKMVKETMDKKFGAAWHVIIGEGYGFEITHETKNLLYMYFGGNMAIVL
WKCS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003774motor activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005856cytoskeleton
GO:0005874microtubule
GO:0030286dynein complex
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0002032epidermal cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR037177DLC_sf
IPR001372Dynein_light_chain_typ-1/2
Vocabulary: biological process
TermDefinition
GO:0007017microtubule-based process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001372Dynein light chain, type 1/2SMARTSM01375Dynein_light_2coord: 14..103
e-value: 2.1E-41
score: 153.5
IPR001372Dynein light chain, type 1/2PFAMPF01221Dynein_lightcoord: 19..103
e-value: 5.1E-28
score: 97.2
IPR001372Dynein light chain, type 1/2PANTHERPTHR11886DYNEIN LIGHT CHAINcoord: 5..104
IPR037177Dynein light chain superfamilyGENE3DG3DSA:3.30.740.10coord: 5..104
e-value: 1.1E-27
score: 97.9
IPR037177Dynein light chain superfamilySUPERFAMILYSSF54648DLCcoord: 12..103
NoneNo IPR availablePANTHERPTHR11886:SF73DYNEIN LIGHT CHAIN 4, AXONEMALcoord: 5..104