G_PROTEIN_RECEP_F3_4 domain-containing protein

Overview


Name	G_PROTEIN_RECEP_F3_4 domain-containing protein
Smed ID	SMED30026937
Length (bp)	676

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30026937

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30026937	h1SMcG0010057	dd_Smed_v6_77671_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
oocyte	SMED30026937	h1SMcG0010057	Contig9714	newmark_ests	PMID:28434803 Rouhana et al., 2017
oocyte	SMED30026937	h1SMcG0010057	Contig9714	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30026937	h1SMcG0010057	Contig9714	newmark_ests	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30026937	h1SMcG0010057	Contig9714	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Human
Match: GRM1 (glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593])

HSP 1 Score: 65.4698 bits (158), Expect = 8.648e-12
Identity = 57/227 (25.11%), Postives = 102/227 (44.93%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP  +   C  I  + + W++  SI+A   +CLG +  L +  ++V  R + ++K+SS    + IL  +FL Y+       + +   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I V   L+++L         +  P+ KE Y  ++CN        P+G+N L ++  TY+
Sbjct:  547 CTACKENEYVQ-DEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVY--LICNTSNLGVVAPLGYNGLLIMSCTYY 770

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Human
Match: GRM1 (glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593])

HSP 1 Score: 65.4698 bits (158), Expect = 9.147e-12
Identity = 57/227 (25.11%), Postives = 102/227 (44.93%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP  +   C  I  + + W++  SI+A   +CLG +  L +  ++V  R + ++K+SS    + IL  +FL Y+       + +   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I V   L+++L         +  P+ KE Y  ++CN        P+G+N L ++  TY+
Sbjct:  547 CTACKENEYVQ-DEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVY--LICNTSNLGVVAPLGYNGLLIMSCTYY 770

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Human
Match: GRM1 (glutamate metabotropic receptor 1 [Source:HGNC Symbol;Acc:HGNC:4593])

HSP 1 Score: 65.4698 bits (158), Expect = 9.147e-12
Identity = 57/227 (25.11%), Postives = 102/227 (44.93%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP  +   C  I  + + W++  SI+A   +CLG +  L +  ++V  R + ++K+SS    + IL  +FL Y+       + +   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I V   L+++L         +  P+ KE Y  ++CN        P+G+N L ++  TY+
Sbjct:  547 CTACKENEYVQ-DEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVY--LICNTSNLGVVAPLGYNGLLIMSCTYY 770

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Human
Match: GRM5 (glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597])

HSP 1 Score: 65.0846 bits (157), Expect = 1.357e-11
Identity = 55/227 (24.23%), Postives = 98/227 (43.17%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP ++   C LI  Q + W     I A + ACLG +  L +  V++  R + ++K+SS    + IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  ++I +   ++++L       +    P+ +E Y  ++CN        P+G+N L +L  T++
Sbjct:  534 CTPCKENEY-VFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVY--LICNTTNLGVVTPLGYNGLLILSCTFY 757

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Human
Match: GRM5 (glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597])

HSP 1 Score: 64.6994 bits (156), Expect = 1.632e-11
Identity = 55/227 (24.23%), Postives = 98/227 (43.17%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP ++   C LI  Q + W     I A + ACLG +  L +  V++  R + ++K+SS    + IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  ++I +   ++++L       +    P+ +E Y  ++CN        P+G+N L +L  T++
Sbjct:  534 CTPCKENEY-VFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVY--LICNTTNLGVVTPLGYNGLLILSCTFY 757

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Celegans
Match: mgl-2 (Metabotropic GLutamate receptor family [Source:UniProtKB/TrEMBL;Acc:A0A0K3AU50])

HSP 1 Score: 67.3958 bits (163), Expect = 7.613e-13
Identity = 53/230 (23.04%), Postives = 107/230 (46.52%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKG---GSNAKFTSNRFVLSVNLVIIFVDAVLL---LSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C +C+D +  +    +C++C    WP  N   C  I P+++SW S+  ILA +LA  G +T++  + V++   ++ ++K+++   S+ IL  L   Y          S   C I   +      VVY++ L KT RI R+  G K        +F +    + +  +++ V  V++   L   + +  + +  +P    + + + C+ +   F IP  W++  + + T +
Sbjct:  531 CESCLDIQYVNKTTNQCMNCTLGSWPNANRTGCEYIIPEVVSWTSFGHILALVLAVTGIITSMATLAVFLRHNSTPVVKSTTRELSYIILSGLVACYAVSFALLATPSTTSCFITRVIPPIAFAVVYSALLTKTNRIARILAGSKKRILTKKPRFLTTFSQVVITWILVAVQCVIVGVGLMRDWPDATYAKYALP----RKLILECDTETKSFLIPFFWDFFLITLCTLY 756

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Celegans
Match: mgl-2 (Metabotropic GLutamate receptor family [Source:UniProtKB/TrEMBL;Acc:A0A0K3AU50])

HSP 1 Score: 67.3958 bits (163), Expect = 7.765e-13
Identity = 42/145 (28.97%), Postives = 72/145 (49.66%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIK 437
            C +C+D +  +    +C++C    WP  N   C  I P+++SW S+  ILA +LA  G +T++  + V++   ++ ++K+++   S+ IL  L   Y          S   C I   +      VVY++ L KT RI R+  G K
Sbjct:  531 CESCLDIQYVNKTTNQCMNCTLGSWPNANRTGCEYIIPEVVSWTSFGHILALVLAVTGIITSMATLAVFLRHNSTPVVKSTTRELSYIILSGLVACYAVSFALLATPSTTSCFITRVIPPIAFAVVYSALLTKTNRIARILAGSK 675

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Celegans
Match: mgl-2 (Metabotropic GLutamate receptor family [Source:UniProtKB/TrEMBL;Acc:A0A0K3AU50])

HSP 1 Score: 67.3958 bits (163), Expect = 8.379e-13
Identity = 53/230 (23.04%), Postives = 107/230 (46.52%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKG---GSNAKFTSNRFVLSVNLVIIFVDAVLL---LSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C +C+D +  +    +C++C    WP  N   C  I P+++SW S+  ILA +LA  G +T++  + V++   ++ ++K+++   S+ IL  L   Y          S   C I   +      VVY++ L KT RI R+  G K        +F +    + +  +++ V  V++   L   + +  + +  +P    + + + C+ +   F IP  W++  + + T +
Sbjct:  531 CESCLDIQYVNKTTNQCMNCTLGSWPNANRTGCEYIIPEVVSWTSFGHILALVLAVTGIITSMATLAVFLRHNSTPVVKSTTRELSYIILSGLVACYAVSFALLATPSTTSCFITRVIPPIAFAVVYSALLTKTNRIARILAGSKKRILTKKPRFLTTFSQVVITWILVAVQCVIVGVGLMRDWPDATYAKYALP----RKLILECDTETKSFLIPFFWDFFLITLCTLY 756

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Celegans
Match: mgl-1 (Probable metabotropic glutamate receptor mgl-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09630])

HSP 1 Score: 48.9062 bits (115), Expect = 1.417e-6
Identity = 41/157 (26.11%), Postives = 72/157 (45.86%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCI---LITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTS 464
            C  C D E   I+   C+ C +  WP ++   C    L   + + W S  S++  +LA  G +  L +I VYV    + ++KAS    S+ +L S+ + Y    +   + S   C I      +    +Y++  +KT RI+R+F+  +     +F S
Sbjct:  497 CSKCEDYEY-LINETHCVGCEQGWWPTKDRKGCFDLSLSQLKYMRWRSMYSLVPTILAVFGIIATLFVIVVYVIYNETPVVKASGRELSYILLISMIMCYCMTFVLLSKPSAIVCAIKRTGIGFAFSCLYSAMFVKTNRIFRIFS-TRSAQRPRFIS 651

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Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCI---LITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTS 464
            C  C D E   I+   C+ C +  WP ++   C    L   + + W S  S++  +LA  G +  L +I VYV    + ++KAS    S+ +L S+ + Y    +   + S   C I      +    +Y++  +KT RI+R+F+  +     +F S
Sbjct:  497 CSKCEDYEY-LINETHCVGCEQGWWPTKDRKGCFDLSLSQLKYMRWRSMYSLVPTILAVFGIIATLFVIVVYVIYNETPVVKASGRELSYILLISMIMCYCMTFVLLSKPSAIVCAIKRTGIGFAFSCLYSAMFVKTNRIFRIFS-TRSAQRPRFIS 651

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Zebrafish
Match: grm1a (glutamate receptor, metabotropic 1a [Source:ZFIN;Acc:ZDB-GENE-030131-7893])

HSP 1 Score: 70.8626 bits (172), Expect = 8.865e-14
Identity = 59/230 (25.65%), Postives = 102/230 (44.35%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQI-QMPNSKEKY-----VEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE    D   C +C    WP +    C  +  + + W S  SI+A + +C+G +  L + +++     + ++K+SS    + IL  +FL YI         +   C +   L      + Y++ + KT RI R+  G K     +    RF+ +   V+I   A +L+SLQ      L + + P   + Y     V ++CN        P+G+N L ++  TY+
Sbjct:  552 CTTCKDNEYVQ-DEFTCRACDLGWWPDDELAECKPLPLKYLEWGSVESIIAVVFSCVGILVTLFVTFIFFQYSDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPTVISCYLQRILVGLSSAMCYSALVTKTNRIARILAGSKKKICTR--KPRFMSAWAQVVI---AFMLISLQLAVVVTLMVLEPPEPVKSYPSIREVYLICNTSNVGVVAPLGYNGLLIMSCTYY 775

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Zebrafish
Match: grm1a (glutamate receptor, metabotropic 1a [Source:ZFIN;Acc:ZDB-GENE-030131-7893])

HSP 1 Score: 70.8626 bits (172), Expect = 9.480e-14
Identity = 59/230 (25.65%), Postives = 102/230 (44.35%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQI-QMPNSKEKY-----VEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE    D   C +C    WP +    C  +  + + W S  SI+A + +C+G +  L + +++     + ++K+SS    + IL  +FL YI         +   C +   L      + Y++ + KT RI R+  G K     +    RF+ +   V+I   A +L+SLQ      L + + P   + Y     V ++CN        P+G+N L ++  TY+
Sbjct:  560 CTTCKDNEYVQ-DEFTCRACDLGWWPDDELAECKPLPLKYLEWGSVESIIAVVFSCVGILVTLFVTFIFFQYSDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPTVISCYLQRILVGLSSAMCYSALVTKTNRIARILAGSKKKICTR--KPRFMSAWAQVVI---AFMLISLQLAVVVTLMVLEPPEPVKSYPSIREVYLICNTSNVGVVAPLGYNGLLIMSCTYY 783

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Zebrafish
Match: grm1b (glutamate receptor, metabotropic 1b [Source:ZFIN;Acc:ZDB-GENE-090821-3])

HSP 1 Score: 68.1662 bits (165), Expect = 7.853e-13
Identity = 61/230 (26.52%), Postives = 101/230 (43.91%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQF-YNNKFLQIQMPNSKEKY-----VEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE    D   C +C    WP E    C  +  + + W+   SI A + +CLG +    +  V++  R + ++K+SS    + IL  +FL YI         S   C +   L      + Y++ + KT RI R+  G K     +    RF+ +   V+I   A +L+S+Q       + ++ P   + Y     V ++CN        P+G+N L +L  TY+
Sbjct:  547 CTPCKDNEYVQ-DEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTR--KPRFMSAWAQVVI---AFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYY 770

[Close]

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQF-YNNKFLQIQMPNSKEKY-----VEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE    D   C +C    WP E    C  +  + + W+   SI A + +CLG +    +  V++  R + ++K+SS    + IL  +FL YI         S   C +   L      + Y++ + KT RI R+  G K     +    RF+ +   V+I   A +L+S+Q       + ++ P   + Y     V ++CN        P+G+N L +L  TY+
Sbjct:  547 CTPCKDNEYVQ-DEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTR--KPRFMSAWAQVVI---AFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYY 770

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Zebrafish
Match: grm2a (glutamate receptor, metabotropic 2a [Source:ZFIN;Acc:ZDB-GENE-030131-8097])

HSP 1 Score: 62.003 bits (149), Expect = 9.459e-11
Identity = 47/214 (21.96%), Postives = 96/214 (44.86%), Query Frame = 3

Query:   36 IDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSN-AKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            +D   C  C   QWP +N   C  +  + I W    +I    +ACLG +  L +I +++    + ++KAS    S+ +L  + L Y    +Y  + S   C +          V Y++ L KT RI R+F G+K G+   +F S    +++   +I    ++++         ++ ++   +   V + CN       + + +N + +++ T++
Sbjct:  334 LDEFTCADCSFGQWPLDNLTGCYDLPEEYIHWEDAWAIGPVSIACLGMLCTLFVIGLFLKNNETPVVKASGRELSYILLLGVLLCYFMTFIYISKPSAVVCTLRRLGLGTSFAVCYSALLTKTNRIARIFNGVKDGAQRPRFISPASQVAICAALISCQLLVVVVWLLVEAPGVRKEVSPERRDVVTLKCNSKDSSMLMSLTYNCVLIILCTFY 547

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Xenopus
Match: GRM1 (glutamate receptor, metabotropic 1 [Source:NCBI gene;Acc:100495945])

HSP 1 Score: 66.2402 bits (160), Expect = 5.097e-12
Identity = 56/227 (24.67%), Postives = 101/227 (44.49%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C +  WP      C  I  + + W+   SI+A   +CLG +  + +  +++  R + ++K+SS    + IL  +FL YI       + +   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I +   L++SL         +  P+ KE Y  ++CN        P+G+N L ++  TY+
Sbjct:  545 CTPCKENEFVQ-DEFTCKACDQGAWPNPGLTGCEPIPVKYLQWSDIESIIAVAFSCLGILITMFVTLIFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSACAQVVIASILISLQLSLVVSLIIMEPPMPILSYPSIKEVY--LICNTSNLGVVAPLGYNGLLIMSCTYY 768

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Xenopus
Match: GRM5 (glutamate receptor, metabotropic 5 [Source:NCBI gene;Acc:100485273])

HSP 1 Score: 63.5438 bits (153), Expect = 3.572e-11
Identity = 52/227 (22.91%), Postives = 101/227 (44.49%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE+   D   C +C    WP ++   C  I  + + W+    I A + +CLG +  + ++ +++  R + ++K+SS    + IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  V+I +   ++++L       +    P+ +E Y  ++CN +      P+G+N L +L  T++
Sbjct:  540 CTPCKDNEI-VFDEYTCKACDLGSWPTDDLTGCDPIPVEFLRWSDPEPIAAVVFSCLGLLATMFVMAIFILYRDTPVVKSSSRELCYIILAGICLGYLCTFSLIAKPQQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFVLICIQLGIIVALFIMEPPDVIFDYPSIREVY--LICNTNNLGVVTPLGYNGLLILSCTFY 763

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Xenopus
Match: GRM5 (glutamate receptor, metabotropic 5 [Source:NCBI gene;Acc:100485273])

HSP 1 Score: 63.5438 bits (153), Expect = 4.377e-11
Identity = 52/227 (22.91%), Postives = 101/227 (44.49%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE+   D   C +C    WP ++   C  I  + + W+    I A + +CLG +  + ++ +++  R + ++K+SS    + IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  V+I +   ++++L       +    P+ +E Y  ++CN +      P+G+N L +L  T++
Sbjct:  529 CTPCKDNEI-VFDEYTCKACDLGSWPTDDLTGCDPIPVEFLRWSDPEPIAAVVFSCLGLLATMFVMAIFILYRDTPVVKSSSRELCYIILAGICLGYLCTFSLIAKPQQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFVLICIQLGIIVALFIMEPPDVIFDYPSIREVY--LICNTNNLGVVTPLGYNGLLILSCTFY 752

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Xenopus
Match: GRM5 (glutamate receptor, metabotropic 5 [Source:NCBI gene;Acc:100485273])

HSP 1 Score: 63.5438 bits (153), Expect = 4.508e-11
Identity = 52/227 (22.91%), Postives = 101/227 (44.49%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE+   D   C +C    WP ++   C  I  + + W+    I A + +CLG +  + ++ +++  R + ++K+SS    + IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  V+I +   ++++L       +    P+ +E Y  ++CN +      P+G+N L +L  T++
Sbjct:  540 CTPCKDNEI-VFDEYTCKACDLGSWPTDDLTGCDPIPVEFLRWSDPEPIAAVVFSCLGLLATMFVMAIFILYRDTPVVKSSSRELCYIILAGICLGYLCTFSLIAKPQQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFVLICIQLGIIVALFIMEPPDVIFDYPSIREVY--LICNTNNLGVVTPLGYNGLLILSCTFY 763

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Xenopus
Match: GRM5 (glutamate receptor, metabotropic 5 [Source:NCBI gene;Acc:100485273])

HSP 1 Score: 63.1586 bits (152), Expect = 4.780e-11
Identity = 52/227 (22.91%), Postives = 101/227 (44.49%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE+   D   C +C    WP ++   C  I  + + W+    I A + +CLG +  + ++ +++  R + ++K+SS    + IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  V+I +   ++++L       +    P+ +E Y  ++CN +      P+G+N L +L  T++
Sbjct:  540 CTPCKDNEI-VFDEYTCKACDLGSWPTDDLTGCDPIPVEFLRWSDPEPIAAVVFSCLGLLATMFVMAIFILYRDTPVVKSSSRELCYIILAGICLGYLCTFSLIAKPQQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFVLICIQLGIIVALFIMEPPDVIFDYPSIREVY--LICNTNNLGVVTPLGYNGLLILSCTFY 763

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Mouse
Match: Grm1 (glutamate receptor, metabotropic 1 [Source:MGI Symbol;Acc:MGI:1351338])

HSP 1 Score: 68.1662 bits (165), Expect = 7.545e-13
Identity = 59/227 (25.99%), Postives = 101/227 (44.49%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP      C  IT + + W+   SI+A   +CLG +  L +  ++V  R + ++K+SS    + IL  +FL Y+       + +   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I V   L+++L         +  P+ KE Y  ++CN        PVG+N L ++  TY+
Sbjct:  547 CTACKENEFVQ-DEFTCRACDLGWWPNAELTGCEPITIRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVY--LICNTSNLGVVAPVGYNGLLIMSCTYY 770

[Close]

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP      C  IT + + W+   SI+A   +CLG +  L +  ++V  R + ++K+SS    + IL  +FL Y+       + +   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I V   L+++L         +  P+ KE Y  ++CN        PVG+N L ++  TY+
Sbjct:  547 CTACKENEFVQ-DEFTCRACDLGWWPNAELTGCEPITIRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVY--LICNTSNLGVVAPVGYNGLLIMSCTYY 770

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Mouse
Match: Grm1 (glutamate receptor, metabotropic 1 [Source:MGI Symbol;Acc:MGI:1351338])

HSP 1 Score: 66.2402 bits (160), Expect = 3.369e-12
Identity = 59/227 (25.99%), Postives = 101/227 (44.49%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP      C  IT + + W+   SI+A   +CLG +  L +  ++V  R + ++K+SS    + IL  +FL Y+       + +   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I V   L+++L         +  P+ KE Y  ++CN        PVG+N L ++  TY+
Sbjct:  547 CTACKENEFVQ-DEFTCRACDLGWWPNAELTGCEPITIRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVY--LICNTSNLGVVAPVGYNGLLIMSCTYY 770

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Mouse
Match: Grm5 (glutamate receptor, metabotropic 5 [Source:MGI Symbol;Acc:MGI:1351342])

HSP 1 Score: 65.0846 bits (157), Expect = 1.013e-11
Identity = 54/227 (23.79%), Postives = 98/227 (43.17%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP ++   C LI  Q + W     I A + ACLG +  L +  +++  R + ++K+SS    + IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  ++I +   ++++L       +    P+ +E Y  ++CN        P+G+N L +L  T++
Sbjct:  533 CTPCKENEY-VFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVIFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVY--LICNTTNLGVVTPLGYNGLLILSCTFY 756

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Mouse
Match: Grm2 (glutamate receptor, metabotropic 2 [Source:MGI Symbol;Acc:MGI:1351339])

HSP 1 Score: 64.3142 bits (155), Expect = 1.118e-11
Identity = 47/194 (24.23%), Postives = 86/194 (44.33%), Query Frame = 3

Query:   36 IDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIK-GGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCN-RD 611
            +D   C  C    WP  +   C  +  + I W    ++    +ACLGA+  L ++ V+V   A+ ++KAS     + +LG +FL Y    ++  + S   C +          V Y++ L KT RI R+F G + G    +F S    +++ L +I    +++ +        +  +    + + V + CN RD
Sbjct:   62 LDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVAAWLVVEAPGIGKETAPERREVVTLRCNHRD 255

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. UniProt/SwissProt
Match: sp|P97772|GRM1_MOUSE (Metabotropic glutamate receptor 1 OS=Mus musculus OX=10090 GN=Grm1 PE=1 SV=2)

HSP 1 Score: 66.2402 bits (160), Expect = 2.356e-11
Identity = 59/227 (25.99%), Postives = 101/227 (44.49%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP      C  IT + + W+   SI+A   +CLG +  L +  ++V  R + ++K+SS    + IL  +FL Y+       + +   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I V   L+++L         +  P+ KE Y  ++CN        PVG+N L ++  TY+
Sbjct:  547 CTACKENEFVQ-DEFTCRACDLGWWPNAELTGCEPITIRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVY--LICNTSNLGVVAPVGYNGLLIMSCTYY 770

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. UniProt/SwissProt
Match: sp|P41594|GRM5_HUMAN (Metabotropic glutamate receptor 5 OS=Homo sapiens OX=9606 GN=GRM5 PE=1 SV=2)

HSP 1 Score: 65.0846 bits (157), Expect = 6.517e-11
Identity = 55/227 (24.23%), Postives = 98/227 (43.17%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP ++   C LI  Q + W     I A + ACLG +  L +  V++  R + ++K+SS    + IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  ++I +   ++++L       +    P+ +E Y  ++CN        P+G+N L +L  T++
Sbjct:  534 CTPCKENEY-VFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVY--LICNTTNLGVVTPLGYNGLLILSCTFY 757

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3UVX5|GRM5_MOUSE (Metabotropic glutamate receptor 5 OS=Mus musculus OX=10090 GN=Grm5 PE=1 SV=2)

HSP 1 Score: 65.0846 bits (157), Expect = 7.085e-11
Identity = 54/227 (23.79%), Postives = 98/227 (43.17%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP ++   C LI  Q + W     I A + ACLG +  L +  +++  R + ++K+SS    + IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  ++I +   ++++L       +    P+ +E Y  ++CN        P+G+N L +L  T++
Sbjct:  533 CTPCKENEY-VFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVIFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVY--LICNTTNLGVVTPLGYNGLLILSCTFY 756

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. UniProt/SwissProt
Match: sp|P31424|GRM5_RAT (Metabotropic glutamate receptor 5 OS=Rattus norvegicus OX=10116 GN=Grm5 PE=1 SV=2)

HSP 1 Score: 64.6994 bits (156), Expect = 7.287e-11
Identity = 54/227 (23.79%), Postives = 98/227 (43.17%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP ++   C LI  Q + W     I A + ACLG +  L +  +++  R + ++K+SS    + IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  ++I +   ++++L       +    P+ +E Y  ++CN        P+G+N L +L  T++
Sbjct:  533 CTPCKENEY-VFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVIFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVY--LICNTTNLGVVTPLGYNGLLILSCTFY 756

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. UniProt/SwissProt
Match: sp|P23385|GRM1_RAT (Metabotropic glutamate receptor 1 OS=Rattus norvegicus OX=10116 GN=Grm1 PE=1 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 8.957e-11
Identity = 58/227 (25.55%), Postives = 100/227 (44.05%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP      C  I  + + W+   SI+A   +CLG +  L +  ++V  R + ++K+SS    + IL  +FL Y+       + +   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I V   L+++L         +  P+ KE Y  ++CN        PVG+N L ++  TY+
Sbjct:  547 CTACKENEFVQ-DEFTCRACDLGWWPNAELTGCEPIPVRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVY--LICNTSNLGVVAPVGYNGLLIMSCTYY 770

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. TrEMBL
Match: A0A2R2MRZ1 (metabotropic glutamate receptor 5 OS=Lingula unguis OX=7574 GN=LOC106155347 PE=3 SV=1)

HSP 1 Score: 85.1149 bits (209), Expect = 2.429e-15
Identity = 58/203 (28.57%), Postives = 100/203 (49.26%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENT-DTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLF-TGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCN 605
            CR+C DNE+   +   C++CP FQWP+++T  +C  I  + + W   ++I   ++A LG +  +     Y+     RL+KASS   SF +L  + L Y++ +++     +Y C             +Y     +T RIYR+F TG K     KF S R  +++  + I V  ++ +          ++ MP   E++VE+ CN
Sbjct:  333 CRHCRDNEITINNASTCLACPIFQWPEQSTFTSCEPIAAEHVRWGDPLAIGIVIVALLGLLATVATSVFYIRFNKERLIKASSRELSFLMLIGILLGYVTAIIFLATPKDYLCYCEYLGFSLSFSWLYAPLATRTNRIYRIFNTGKKSTIRPKFISPRSQVTIATIFITVQVIISIITAIVVPPTAELSMPVKTERFVELYCN 535

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. TrEMBL
Match: A0A1S3HQU1 (metabotropic glutamate receptor 3 OS=Lingula unguis OX=7574 GN=LOC106156989 PE=3 SV=1)

HSP 1 Score: 77.411 bits (189), Expect = 1.030e-12
Identity = 51/225 (22.67%), Postives = 109/225 (48.44%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLF-TGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            CR C +NE    ++  C  CPE  WP E+  +C  + P+ + W   ++I     + +G +    I+  ++    ++L+KA S   ++ IL  +F++Y++ + +  +  ++ C +  F        +Y     +T RIYR+F +G K        S R  + +  ++I ++ ++ +     N   ++ +MP   EK+VE++C   I      + +N L + + +++
Sbjct:  737 CRKCRNNEYLVSNQTSCKECPELMWPVESLTSCESVQPEHMRWGDSLAITILTFSIIGIILAAFILAFFIRHNNAKLIKACSRELAYLILTGVFVSYLTAIFFLAKPEDHFCYVEHFGFSLSFAWIYAPLFTRTNRIYRIFASGKKTKKRPPLVSPRSQVIIASLLITIEVIISIITAAVNPPGIEQRMPVKTEKFVELLCKLPIQGIVASLAYNILLVAMCSFY 961

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. TrEMBL
Match: V4AGY8 (G_PROTEIN_RECEP_F3_4 domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_145056 PE=3 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 2.161e-12
Identity = 60/229 (26.20%), Postives = 112/229 (48.91%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTD--TCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLF-TGIKGGSNAKFTSNRFVLSVNLVIIF--VDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C++C  NE+ + +   C SCP F+WP+  TD  +C  I P  I W+   +I+    + +G +  + I+  Y+    S  +KASS   S+F+L  + + Y+++     +   + C +  F        +Y   L +T RIYR+F +G K     +F  ++  + + ++ +F  V   ++  L +       +Q+P   +KYVE+ CN  +      + +N L +L  TY+
Sbjct:  521 CKSCRSNEMVTNNGTSCESCPMFEWPELETDLKSCSPIPPVTIDWSEPFAIMLVTFSFIGIVLAISILVFYIKYNESSFIKASSRDLSYFMLTGVCIGYLTVFGMVTKPETWSCKMVFFCFCISFTCIYGPLLTRTIRIYRIFESGKKSNKRPRFIGSKTQIVIAMLFVFGQVAISIVFVLWYSPEATRTMQVPT--QKYVELSCNMPLAGLISFLSYNILLVLTCTYF 747

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. TrEMBL
Match: A0A1S3JY51 (metabotropic glutamate receptor OS=Lingula unguis OX=7574 GN=LOC106176936 PE=3 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 3.119e-12
Identity = 51/225 (22.67%), Postives = 109/225 (48.44%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLF-TGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            CR C +NE    ++  C  CPE  WP E+  +C  + P+ + W   ++I     + +G +    I+  ++    ++L+KA S   ++ IL  +F++Y++ + +  +  ++ C +  F        +Y     +T RIYR+F +G K        S R  + +  ++I ++ ++ +     N   ++ +MP   EK+VE++C   I      + +N L + + +++
Sbjct:  332 CRKCRNNEYLVSNQTSCKECPELMWPVESLTSCESVQPEHMRWGDSLAITILTFSIIGIILAAFILAFFIRHNNAKLIKACSRELAYLILTGVFVSYLTAIFFLAKPEDHFCYVEHFGFSLSFAWIYAPLFTRTNRIYRIFASGKKTKKRPPLVSPRSQVIIASLLITIEVIISIITAAVNPPGIEQRMPVKTEKFVELLCKLPIQGIVASLAYNILLVAMCSFY 556

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. TrEMBL
Match: A0A3B3TDJ6 (Glutamate receptor, metabotropic 1b OS=Paramormyrops kingsleyae OX=1676925 PE=3 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 5.663e-12
Identity = 61/230 (26.52%), Postives = 107/230 (46.52%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQF-YNNKFLQIQMPNSKEKY-----VEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C +C DNE    D   C +C    WP E  + C  I  + + W++  SI+A + +CLG +  + + +++V  R + ++K+SS    + IL  +FL YI         +   C +   L      + Y++ + KT RI R+  G K     +    RF+ +   V+I   A +L+S+Q       L ++ P   + Y     V ++CN        P+G+N L ++  TY+
Sbjct:  546 CTSCKDNEYVQ-DEFTCKACELGWWPDEELEGCQPIPLRYLQWSNAESIVAVVFSCLGILVTMFVTFIFVLYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPTVASCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTR--KPRFMSAWAQVVI---AFVLISIQLTLEVTLLILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLIMSCTYY 769

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Cavefish
Match: grm1a (glutamate receptor, metabotropic 1a [Source:ZFIN;Acc:ZDB-GENE-030131-7893])

HSP 1 Score: 73.9442 bits (180), Expect = 7.332e-15
Identity = 59/230 (25.65%), Postives = 105/230 (45.65%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQF-YNNKFLQIQMPNSKEKY-----VEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE    D   C +C    WP +    C  +  + + W+S  SI+A + +CLG +  L + +V++  R + ++K+SS    + IL  +F+ YI         +   C +   L      + Y++ + KT RI R+  G K     +    RF+ +   V+I   A +L+S+Q       + ++ P   + Y     V ++CN        P+G+N L ++  TY+
Sbjct:  541 CTTCKDNEYVQ-DEFTCKACDLGWWPDDELAGCQPLPLKYLEWSSVESIVAVVFSCLGILVTLFVTFVFIQYRDTPVVKSSSRELCYIILAGIFMGYICPFTLIARPTVISCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTR--KPRFMSAWAQVVI---AFILISMQLTLEVTLIVLEPPEPIKSYPSIREVYLICNTSNVGMIAPLGYNGLLIMSCTYY 764

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Cavefish
Match: grm5a (metabotropic glutamate receptor 5-like [Source:NCBI gene;Acc:103040533])

HSP 1 Score: 67.0106 bits (162), Expect = 1.433e-12
Identity = 55/227 (24.23%), Postives = 98/227 (43.17%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE    D   C +C    WP ++   C  I  Q + W     I A + ACLG +  + ++ ++V    + ++K+SS    F IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  ++IF+   ++++L       +    P+ +E  V ++CN        P+G+N L +L  T++
Sbjct:  543 CTPCKDNEY-VFDEYTCRACELGSWPTDDLTGCEPIPVQYLLWGDPEPIAAVVFACLGLLATIFVMLIFVRFHDTPVVKSSSRELCFIILAGICLGYLCTFCLIAKPHVVYCYLQRLGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILIFLQLAIIVALFIMEPPQVIYDYPSIRE--VHLICNTTTLGVVAPLGYNGLLILSCTFY 766

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Cavefish
Match: grm5a (metabotropic glutamate receptor 5-like [Source:NCBI gene;Acc:103040533])

HSP 1 Score: 66.6254 bits (161), Expect = 2.040e-12
Identity = 55/227 (24.23%), Postives = 98/227 (43.17%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE    D   C +C    WP ++   C  I  Q + W     I A + ACLG +  + ++ ++V    + ++K+SS    F IL  + L Y+       +     C +          + Y++ + KT RI R+  G K        +F S    L +  ++IF+   ++++L       +    P+ +E  V ++CN        P+G+N L +L  T++
Sbjct:  526 CTPCKDNEY-VFDEYTCRACELGSWPTDDLTGCEPIPVQYLLWGDPEPIAAVVFACLGLLATIFVMLIFVRFHDTPVVKSSSRELCFIILAGICLGYLCTFCLIAKPHVVYCYLQRLGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILIFLQLAIIVALFIMEPPQVIYDYPSIRE--VHLICNTTTLGVVAPLGYNGLLILSCTFY 749

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Cavefish
Match: grm1b (glutamate receptor, metabotropic 1b [Source:ZFIN;Acc:ZDB-GENE-090821-3])

HSP 1 Score: 63.5438 bits (153), Expect = 2.287e-11
Identity = 59/227 (25.99%), Postives = 97/227 (42.73%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE    D   C +C    WP E    C  I  + + W    SI A + +CLG +    + +V++  R + ++K+SS    + IL  +FL YI         S   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I V   L ++L            P+ +E +  ++CN        P+G+N L +L  TY+
Sbjct:  550 CTACKDNEYVQ-DEFTCKACELGWWPDEELHGCEPIPLRYLEWGHPESIAAVVFSCLGILVTSFVTFVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSLASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISVQLTLEITLIILEPPEPIKSYPSIREVF--LICNTSNMGMVAPLGYNGLLILSCTYY 773

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Cavefish
Match: grm6b (metabotropic glutamate receptor 6-like [Source:NCBI gene;Acc:111195348])

HSP 1 Score: 60.4622 bits (145), Expect = 2.607e-10
Identity = 51/167 (30.54%), Postives = 79/167 (47.31%), Query Frame = 3

Query:   36 IDRLRCISCPEFQWPQENTDTCILITPQI-ISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLF-TGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSL 530
            +D   C +CP    P  N   C   TP I + W+S  +I+   LA LG +   G+I  +V    + +++AS    S+ +L  +FL Y+   L   E     C     L    + + Y++ L KT RIYR+F  G K  +  KF S    L +  ++I   +V LLS+
Sbjct:  558 LDEFNCDTCPFDMRPTPNRTGC-RPTPIIKLEWSSPWAIIPVFLAVLGILATTGVIVTFVRFNDTPIVRASGRELSYVLLTGIFLIYLITFLMIAEPGAVVCAFRRLLLGLGMCISYSAMLTKTNRIYRIFEQGKKSVTPPKFISPTSQLIITFILI---SVQLLSI 720

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Sea Lamprey
Match: casr (calcium-sensing receptor [Source:ZFIN;Acc:ZDB-GENE-050119-8])

HSP 1 Score: 59.3066 bits (142), Expect = 1.356e-10
Identity = 38/142 (26.76%), Postives = 69/142 (48.59%), Query Frame = 3

Query:    3 CRNCIDNEVPS-IDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLF 425
            C +C + E  +  D   C+ CPE  WP  N   C+    + +SW     +    + CLGA+  L +  V+V  R + ++KA+++  S+ +  SLF  ++S L + G+ S   C +          +  +  L+KT R+ ++F
Sbjct:  543 CISCAEGEYNNESDANSCLGCPEDSWPSANHTMCVPKREEYLSWREPFGVCLAFVGCLGAVLTLSVAAVFVKHRGTAIVKATNVELSYLLFFSLFCCFLSSLFFIGKPSTVACKLRQPTFGISFVLCVSCVLVKTHRVLQVF 684

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007590.1 (pep scaffold:Pmarinus_7.0:GL478498:6932:63706:-1 gene:ENSPMAG00000006812.1 transcript:ENSPMAT00000007590.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.1434 bits (126), Expect = 1.485e-8
Identity = 41/143 (28.67%), Postives = 62/143 (43.36%), Query Frame = 3

Query:    3 CRNC--IDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLF 425
            C NC   +     +D   C  CP    P  N   C  I    + W+S  +++   LA LG +T   +I  +V    + +++AS    S+ +L  +FL Y +  L   E S   C          + V Y + L KT RIYR+F
Sbjct:  540 CWNCERCEGYYFQLDEFNCHLCPYNMRPNVNRTGCDAIPIVKLEWHSPFAVVPVFLAILGLLTTAFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYATTFLMIAEPSLAVCSFRRIFLGLGMCVSYAALLTKTNRIYRIF 682

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Sea Lamprey
Match: grm3 (glutamate receptor, metabotropic 3 [Source:ZFIN;Acc:ZDB-GENE-061009-13])

HSP 1 Score: 50.8322 bits (120), Expect = 8.185e-8
Identity = 37/184 (20.11%), Postives = 82/184 (44.57%), Query Frame = 3

Query:   39 DRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIK--GGSNAKFTSNRFVLSVNLVIIFVD-AVLLLSLQFYNNKFLQIQMPNSKE 581
            D   C+ C   +WP  +   C  +  + I W    +++   ++C+G +  + ++  ++    + ++KAS     + +L  + + Y +   +  + +   C +   +      V Y++ L KT RI R+F   +  G S  KF S    + + L +I +  +V+ + L   N    +  +P+ +E
Sbjct:  536 DEFTCMDCGPGRWPSADLRDCYDLPEEYIKWEDAWALVPIAISCIGLICTVTVLITFIVHGNTPIVKASGRELCYALLAGVSMCYSTTFAFVAKATVLVCALRRLVLAASFVVCYSALLTKTNRISRMFNSAREGGSSRPKFVSPLAQMVICLTLILIQLSVVAIWLIVENPGLRRFTIPDKRE 719

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Nematostella
Match: EDO42746 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0J8])

HSP 1 Score: 48.521 bits (114), Expect = 8.379e-7
Identity = 42/162 (25.93%), Postives = 76/162 (46.91%), Query Frame = 3

Query:   30 PSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAV 515
            PS  +  C  CPE     E   +C+ IT + + W S   I+  + + LG M ++ +I +++  R + ++KAS+   SF  L  + LT+       G  S  +C +  F+      +  +  LLKT R+ R+F      + A+ TS   +L+  +  +   A+
Sbjct:  517 PSRGQDGCKGCPEGYEANEMHTSCVQITEEYLRWGSTSGIIVLVFSSLGTMLSITVITIFIKHRETAVVKASNRELSFVHLACILLTFTFPFSLVGRPSRVQCGVWPFVFAVVFCLGTSIMLLKTDRLLRVFR-----AKARLTSRSNLLTNKMQFLTASAL 673

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Medaka
Match: grm1a (glutamate metabotropic receptor 1 [Source:NCBI gene;Acc:101165118])

HSP 1 Score: 68.5514 bits (166), Expect = 4.368e-13
Identity = 55/227 (24.23%), Postives = 98/227 (43.17%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C DNE    D   C +C    WP E  + C  +  + + W    S++A   +C+G +    + +V++  R + ++K+SS    + IL  +FL YI         +   C +   L      + Y++ + KT RI R+  G K        +F S    + +  ++I V   L ++L            P+ +E Y  ++CN        P+G+N L ++  TY+
Sbjct:  553 CTTCKDNEYVQ-DEFTCKACELGWWPDEELEDCQPLPLKYVDWADVESVVAVAFSCVGILITSFVTFVFIQYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPTVASCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFMLISVQLTLEITLIILEPPEPIKSYPSIREVY--LICNTSNVGMVAPLGYNGLLIMSCTYY 776

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Medaka
Match: grm3 (metabotropic glutamate receptor 3 [Source:NCBI gene;Acc:101166047])

HSP 1 Score: 62.3882 bits (150), Expect = 4.826e-11
Identity = 46/166 (27.71%), Postives = 76/166 (45.78%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVII 500
            C  C  +E  + D   C  C   QWP ++  +C  +    I W    +I    +AC+G M    +I+V++    + L+KAS     + +L  +F++Y    L+  + S   C +          V Y++ L KT RI R+F G+K G+ A     RF+   + V I
Sbjct:  531 CTACEAHEYLA-DEFTCAPCAPGQWPTDDLTSCYDLPEDYIMWEDAWAIGPITIACVGFMCTGLVIWVFIRHNNTPLVKASGRELCYILLSGVFMSYAMTFLFLAKPSPAICALRRLGLGTSFAVCYSALLTKTNRIARIFNGVKEGAGA--VRPRFISPFSQVFI 693

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Medaka
Match: stxbp5b (syntaxin-binding protein 5 [Source:NCBI gene;Acc:101172714])

HSP 1 Score: 61.6178 bits (148), Expect = 9.069e-11
Identity = 55/227 (24.23%), Postives = 100/227 (44.05%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGG---SNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C +NE    D   C +C    WP E  + C  I    + W++  SI+  + +CLG +    + +++V  R + ++K+SS    + IL  +FL Y+         +   C +   L  +   + Y++ + KT RI R+  G K        +F S    + +  V+I V   L ++L            P+ +E +  ++CN        P+G+N L ++  TY+
Sbjct:  552 CTACKENEYVQ-DEFTCKACELGWWPDEELEGCQPIPLHYLEWSNPESIIQVVFSCLGILVTSFVAFIFVLYRDTPVVKSSSRELCYIILAGIFLGYLCPFTLLARPTVASCYLQRLLVGFSAAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIASVLISVQLTLEVTLIIMEPPEPIKSYPSIREVF--LICNTSNLGVVAPLGYNGLLIMSCTYY 775

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BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Medaka
Match: grm2a (glutamate metabotropic receptor 2 [Source:NCBI gene;Acc:101169193])

HSP 1 Score: 60.077 bits (144), Expect = 3.301e-10
Identity = 47/214 (21.96%), Postives = 95/214 (44.39%), Query Frame = 3

Query:   36 IDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSN-AKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            +D   C  C   QWP  N   C  +  + I W    +I    ++CLG M+ L +I +++    + ++KAS    S+ +L  + + Y    +Y  + S   C +          V Y++ L KT RI R+F G+K G+   +F S    +++   +I    V+++         ++ ++   +   V + CN       + + +N + +++ T +
Sbjct:  554 LDEFTCADCSFGQWPLANLTGCYDLPEEYIRWEDAWAIGPVTISCLGMMSTLFVIGLFLKHNETPVVKASGRELSYILLLGVLMCYCMTFIYIAKPSTAVCTLRRLGLGTSFAVCYSALLTKTNRIARIFGGVKDGAQRPRFISPASQVAICGALISCQLVVVVVWLLLEAPGVRKEVSPERRDVVTLKCNNRDSSMLLSLTYNCILIILCTVY 767

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Medaka
Match: grm2a (glutamate metabotropic receptor 2 [Source:NCBI gene;Acc:101169193])

HSP 1 Score: 59.6918 bits (143), Expect = 3.916e-10
Identity = 47/214 (21.96%), Postives = 95/214 (44.39%), Query Frame = 3

Query:   36 IDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSN-AKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            +D   C  C   QWP  N   C  +  + I W    +I    ++CLG M+ L +I +++    + ++KAS    S+ +L  + + Y    +Y  + S   C +          V Y++ L KT RI R+F G+K G+   +F S    +++   +I    V+++         ++ ++   +   V + CN       + + +N + +++ T +
Sbjct:  523 LDEFTCADCSFGQWPLANLTGCYDLPEEYIRWEDAWAIGPVTISCLGMMSTLFVIGLFLKHNETPVVKASGRELSYILLLGVLMCYCMTFIYIAKPSTAVCTLRRLGLGTSFAVCYSALLTKTNRIARIFGGVKDGAQRPRFISPASQVAICGALISCQLVVVVVWLLLEAPGVRKEVSPERRDVVTLKCNNRDSSMLLSLTYNCILIILCTVY 736

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Planmine SMEST
Match: SMESG000064459.1 (SMESG000064459.1)

HSP 1 Score: 429.098 bits (1102), Expect = 1.343e-146
Identity = 224/224 (100.00%), Postives = 224/224 (100.00%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVAKRASRLLKASSLRSSFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW
Sbjct:  515 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVAKRASRLLKASSLRSSFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 738

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Planmine SMEST
Match: SMESG000033752.1 (SMESG000033752.1)

HSP 1 Score: 64.3142 bits (155), Expect = 9.584e-12
Identity = 58/230 (25.22%), Postives = 106/230 (46.09%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKF------LQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C  NE   ++  +C  C E +WP +N   C L+T   +  + W++I+  +L+ LG  T   ++ V+   + + +++AS    SF IL    + Y+   ++  + + Y C I   L      V+Y S L KT RI R+F       +A+ T+ R         + + AV L+S+Q  +N          I+    K ++  + C  +   F + + +N L + + TY+
Sbjct:  558 CSLCKSNEF-VVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFIFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIF------ESAQKTAKRPPCISPKSQLMICAV-LISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYY 779

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Planmine SMEST
Match: SMESG000033752.1 (SMESG000033752.1)

HSP 1 Score: 63.929 bits (154), Expect = 1.086e-11
Identity = 58/230 (25.22%), Postives = 106/230 (46.09%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKF------LQIQMPNSKEKYVEMVCNRDIPRFWIPVGWNWLKLLISTYW 674
            C  C  NE   ++  +C  C E +WP +N   C L+T   +  + W++I+  +L+ LG  T   ++ V+   + + +++AS    SF IL    + Y+   ++  + + Y C I   L      V+Y S L KT RI R+F       +A+ T+ R         + + AV L+S+Q  +N          I+    K ++  + C  +   F + + +N L + + TY+
Sbjct:  573 CSLCKSNEF-VVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFIFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIF------ESAQKTAKRPPCISPKSQLMICAV-LISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYY 794

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Planmine SMEST
Match: SMESG000024379.1 (SMESG000024379.1)

HSP 1 Score: 48.521 bits (114), Expect = 1.788e-6
Identity = 35/141 (24.82%), Postives = 68/141 (48.23%), Query Frame = 3

Query:    3 CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLF 425
            C  C   ++ +  +  C+ C   Q P +N   CI IT   +  NS I++   L   +G      ++ +++    S +++ASS   SF +L  + + ++  ++   + +++ C I  F       V Y++ L+KT RI R+F
Sbjct:   85 CIRCQKYDILNKLKTECLPCEMGQIPDKNKTGCINITQSYLEPNSPIALGILLFTSMGICCAATVVIIFIKFINSPIVRASSRELSFILLFGIMMCFVMTIILCTKPTDFNCSIEKFCIGLSFSVCYSALLVKTNRIERIF 225

[Close]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Planmine SMEST
Match: SMESG000064049.1 (SMESG000064049.1)

HSP 1 Score: 48.1358 bits (113), Expect = 2.718e-6
Identity = 43/224 (19.20%), Postives = 101/224 (45.09%), Query Frame = 3

Query:    3 CRNCIDNEV--PSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISILACLLACLGAMTNLGIIYVYVXXXXXXXXXXXXXXXXFFILGSLFLTYISMLLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNAKFTSNRFVLSVNLVIIF---VDAVLLLSLQFYNNKFLQIQMPNSKEKY-----VEMVCNRDIPRFWIPVGWN 644
            C++C +NE+   +     C SC +   P  +   C  I    + W+    I+A + + +G +  + I+ ++     + ++K+ +    + IL  + L+Y++      + + + C++   +      +++ S + KT RI R+ + I      +        +  +VI+F   V  ++++S+  ++N       P SK  Y     V ++CN +    +I +G++
Sbjct:  368 CKDCSENEITNKTFHNESCSSCKKGFRPNSDRSNCSEIPAIFLKWSDASVIVAIIFSIVGLIITVIIVGIFAKYNNTPVVKSCTRELMYVILVGVALSYLTTFPLVWKPTTFSCLLSRIMPGLSFSLIFGSLVTKTNRICRILS-ISKKKIIRRKGRFLTTTAQIVIVFLLNVVEIIIISVMIWHN------FPKSKSDYSVAATVRLICNTESQDLFISMGFD 584

The following BLAST results are available for this feature:

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Human
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Celegans
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Fly
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Zebrafish
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Xenopus
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Mouse
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. UniProt/SwissProt
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. TrEMBL
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Cavefish
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Sea Lamprey
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Yeast
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Nematostella
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Medaka
BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Planmine SMEST

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
GRM1	8.648e-12	25.11	glutamate metabotropic receptor 1 [Source:HGNC Sym...	[more]
GRM1	9.147e-12	25.11	glutamate metabotropic receptor 1 [Source:HGNC Sym...	[more]
GRM1	9.147e-12	25.11	glutamate metabotropic receptor 1 [Source:HGNC Sym...	[more]
GRM5	1.357e-11	24.23	glutamate metabotropic receptor 5 [Source:HGNC Sym...	[more]
GRM5	1.632e-11	24.23	glutamate metabotropic receptor 5 [Source:HGNC Sym...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mgl-2	7.613e-13	23.04	Metabotropic GLutamate receptor family [Source:Un...	[more]
mgl-2	7.765e-13	28.97	Metabotropic GLutamate receptor family [Source:Un...	[more]
mgl-2	8.379e-13	23.04	Metabotropic GLutamate receptor family [Source:Un...	[more]
mgl-1	1.417e-6	26.11	Probable metabotropic glutamate receptor mgl-1 [S...	[more]
mgl-1	1.417e-6	26.11	Probable metabotropic glutamate receptor mgl-1 [S...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
grm1a	8.865e-14	25.65	glutamate receptor, metabotropic 1a [Source:ZFIN;A...	[more]
grm1a	9.480e-14	25.65	glutamate receptor, metabotropic 1a [Source:ZFIN;A...	[more]
grm1b	7.853e-13	26.52	glutamate receptor, metabotropic 1b [Source:ZFIN;A...	[more]
grm1b	7.853e-13	26.52	glutamate receptor, metabotropic 1b [Source:ZFIN;A...	[more]
grm2a	9.459e-11	21.96	glutamate receptor, metabotropic 2a [Source:ZFIN;A...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
GRM1	5.097e-12	24.67	glutamate receptor, metabotropic 1 [Source:NCBI ge...	[more]
GRM5	3.572e-11	22.91	glutamate receptor, metabotropic 5 [Source:NCBI ge...	[more]
GRM5	4.377e-11	22.91	glutamate receptor, metabotropic 5 [Source:NCBI ge...	[more]
GRM5	4.508e-11	22.91	glutamate receptor, metabotropic 5 [Source:NCBI ge...	[more]
GRM5	4.780e-11	22.91	glutamate receptor, metabotropic 5 [Source:NCBI ge...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Grm1	7.545e-13	25.99	glutamate receptor, metabotropic 1 [Source:MGI Sym...	[more]
Grm1	7.545e-13	25.99	glutamate receptor, metabotropic 1 [Source:MGI Sym...	[more]
Grm1	3.369e-12	25.99	glutamate receptor, metabotropic 1 [Source:MGI Sym...	[more]
Grm5	1.013e-11	23.79	glutamate receptor, metabotropic 5 [Source:MGI Sym...	[more]
Grm2	1.118e-11	24.23	glutamate receptor, metabotropic 2 [Source:MGI Sym...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P97772\|GRM1_MOUSE	2.356e-11	25.99	Metabotropic glutamate receptor 1 OS=Mus musculus ...	[more]
sp\|P41594\|GRM5_HUMAN	6.517e-11	24.23	Metabotropic glutamate receptor 5 OS=Homo sapiens ...	[more]
sp\|Q3UVX5\|GRM5_MOUSE	7.085e-11	23.79	Metabotropic glutamate receptor 5 OS=Mus musculus ...	[more]
sp\|P31424\|GRM5_RAT	7.287e-11	23.79	Metabotropic glutamate receptor 5 OS=Rattus norveg...	[more]
sp\|P23385\|GRM1_RAT	8.957e-11	25.55	Metabotropic glutamate receptor 1 OS=Rattus norveg...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2R2MRZ1	2.429e-15	28.57	metabotropic glutamate receptor 5 OS=Lingula ungui...	[more]
A0A1S3HQU1	1.030e-12	22.67	metabotropic glutamate receptor 3 OS=Lingula ungui...	[more]
V4AGY8	2.161e-12	26.20	G_PROTEIN_RECEP_F3_4 domain-containing protein OS=...	[more]
A0A1S3JY51	3.119e-12	22.67	metabotropic glutamate receptor OS=Lingula unguis ...	[more]
A0A3B3TDJ6	5.663e-12	26.52	Glutamate receptor, metabotropic 1b OS=Paramormyro...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
grm1a	7.332e-15	25.65	glutamate receptor, metabotropic 1a [Source:ZFIN;A...	[more]
grm5a	1.433e-12	24.23	metabotropic glutamate receptor 5-like [Source:NCB...	[more]
grm5a	2.040e-12	24.23	metabotropic glutamate receptor 5-like [Source:NCB...	[more]
grm1b	2.287e-11	25.99	glutamate receptor, metabotropic 1b [Source:ZFIN;A...	[more]
grm6b	2.607e-10	30.54	metabotropic glutamate receptor 6-like [Source:NCB...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
casr	1.356e-10	26.76	calcium-sensing receptor [Source:ZFIN;Acc:ZDB-GENE...	[more]
ENSPMAT00000007590.1	1.485e-8	28.67	pep scaffold:Pmarinus_7.0:GL478498:6932:63706:-1 g...	[more]
grm3	8.185e-8	20.11	glutamate receptor, metabotropic 3 [Source:ZFIN;Ac...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO42746	8.379e-7	25.93	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
grm1a	4.368e-13	24.23	glutamate metabotropic receptor 1 [Source:NCBI gen...	[more]
grm3	4.826e-11	27.71	metabotropic glutamate receptor 3 [Source:NCBI gen...	[more]
stxbp5b	9.069e-11	24.23	syntaxin-binding protein 5 [Source:NCBI gene;Acc:1...	[more]
grm2a	3.301e-10	21.96	glutamate metabotropic receptor 2 [Source:NCBI gen...	[more]
grm2a	3.916e-10	21.96	glutamate metabotropic receptor 2 [Source:NCBI gen...	[more]

BLAST of G_PROTEIN_RECEP_F3_4 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000064459.1	1.343e-146	100.00	SMESG000064459.1	[more]
SMESG000033752.1	9.584e-12	25.22	SMESG000033752.1	[more]
SMESG000033752.1	1.086e-11	25.22	SMESG000033752.1	[more]
SMESG000024379.1	1.788e-6	24.82	SMESG000024379.1	[more]
SMESG000064049.1	2.718e-6	19.20	SMESG000064049.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30026937 ID=SMED30026937|Name=G_PROTEIN_RECEP_F3_4 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=676bp
AATGCAGAAATTGTATTGATAACGAAGTTCCGTCCATTGACCGATTGAGA
TGCATTTCATGCCCCGAATTTCAGTGGCCCCAAGAAAATACTGATACGTG
CATTTTAATTACTCCACAAATCATTTCCTGGAACTCGTGGATTTCTATAT
TAGCATGCTTATTAGCTTGTCTTGGAGCAATGACAAATTTAGGCATCATC
TATGTTTATGTAGCAAAAAGAGCGAGTAGACTGTTAAAAGCGAGTTCTTT
AAGAAGCAGTTTCTTTATTTTGGGCTCACTATTTCTAACATATATTAGCA
TGCTACTCTACGCCGGTGAATTGAGTAATTATAAATGTATAATCCACCTC
TTTTTAACTCACTGGCCATTAGGAGTTGTCTATACTAGCACATTACTCAA
AACGTTCAGGATATACAGATTATTTACTGGTATTAAAGGAGGATCAAATG
CGAAATTCACTTCTAATAGGTTCGTTTTATCAGTAAATCTTGTAATAATA
TTTGTGGATGCTGTTCTTCTTCTTAGCCTTCAATTTTACAACAATAAATT
TCTTCAAATTCAAATGCCGAATTCCAAAGAAAAGTACGTGGAAATGGTAT
GCAATCGAGACATTCCTCGATTCTGGATTCCGGTCGGTTGGAACTGGCTG
AAATTACTGATATCAACATATTGGGG

protein sequence of SMED30026937-orf-1

>SMED30026937-orf-1 ID=SMED30026937-orf-1|Name=SMED30026937-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=224bp
CRNCIDNEVPSIDRLRCISCPEFQWPQENTDTCILITPQIISWNSWISIL
ACLLACLGAMTNLGIIYVYVAKRASRLLKASSLRSSFFILGSLFLTYISM
LLYAGELSNYKCIIHLFLTHWPLGVVYTSTLLKTFRIYRLFTGIKGGSNA
KFTSNRFVLSVNLVIIFVDAVLLLSLQFYNNKFLQIQMPNSKEKYVEMVC
NRDIPRFWIPVGWNWLKLLISTYW

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000074	oocyte
PLANA:0000231	vitelline gland

Vocabulary: **INTERPRO**
Term	Definition
IPR038550	GPCR_3_9-Cys_sf
IPR017978	GPCR_3_C

Vocabulary: **biological process**
Term	Definition
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007165	signal transduction
GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0051966	regulation of synaptic transmission, glutamatergic

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0042734	presynaptic membrane

Vocabulary: **molecular function**
Term	Definition
GO:0004930	G-protein coupled receptor activity
GO:0004871	signal transducer activity
GO:0008066	glutamate receptor activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR038550	GPCR, family 3, nine cysteines domain superfamily	GENE3D	G3DSA:2.10.50.30		coord: 1..49 e-value: 1.1E-6 score: 30.3
IPR017978	GPCR family 3, C-terminal	PFAM	PF00003	7tm_3	coord: 63..223 e-value: 2.0E-14 score: 53.9
IPR017978	GPCR family 3, C-terminal	PROSITE	PS50259	G_PROTEIN_RECEP_F3_4	coord: 47..224 score: 12.079
None	No IPR available	PANTHER	PTHR24060	METABOTROPIC GLUTAMATE RECEPTOR	coord: 1..215
None	No IPR available	PANTHER	PTHR24060:SF158	METABOTROPIC GLUTAMATE RECEPTOR	coord: 1..215
None	No IPR available	CDD	cd13953	7tm_classC_mGluR-like	coord: 47..223 e-value: 2.72406E-13 score: 64.9505
None	No IPR available	TMHMM	TMhelix		coord: 81..103
None	No IPR available	TMHMM	TMhelix		coord: 46..68
None	No IPR available	TMHMM	TMhelix		coord: 157..179
None	No IPR available	TMHMM	TMhelix		coord: 113..135

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G_PROTEIN_RECEP_F3_4 domain-containing protein

Zeng et. al., 2018

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

blazegraph-runner