Integrase catalytic domain-containing protein

Overview
NameIntegrase catalytic domain-containing protein
Smed IDSMED30026904
Length (bp)4751
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Integrase catalytic domain-containing protein (SMED30026904) t-SNE clustered cells

Violin plots show distribution of expression levels for Integrase catalytic domain-containing protein (SMED30026904) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Integrase catalytic domain-containing protein (SMED30026904) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Integrase catalytic domain-containing protein (SMED30026904) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30026904

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 2

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30026904SMESG000081946.1 dd_Smed_v4_11923_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30026904SMESG000081946.1 SMESG000042388.1 SMESG000042349.1 OX_Smed_1.0.02705ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A4Y2BNX6 (Uncharacterized transposon-derived protein F54H12.3 OS=Araneus ventricosus OX=182803 GN=F54H12.3_18 PE=4 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 5.471e-8
Identity = 30/52 (57.69%), Postives = 44/52 (84.62%), Query Frame = 3 
Query: 2247 NESKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQ 2402
            +E KEFYN +++Q+LK+ KINHYS HS++KA+ VERFNRTL+++L + F H+
Sbjct:   17 DEGKEFYNKQVQQLLKKNKINHYSSHSEHKASVVERFNRTLKNKLFRIFTHR 68
[Close]
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A4Y2UGM2 (Uncharacterized transposon-derived protein F54H12.3 OS=Araneus ventricosus OX=182803 GN=F54H12.3_50 PE=4 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 5.698e-8
Identity = 30/52 (57.69%), Postives = 44/52 (84.62%), Query Frame = 3 
Query: 2247 NESKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQ 2402
            +E KEFYN +++Q+LK+ KINHYS HS++KA+ VERFNRTL+++L + F H+
Sbjct:   22 DEGKEFYNKQVQQLLKKNKINHYSSHSEHKASVVERFNRTLKNKLFRIFTHR 73
[Close]
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A4Y2HQ68 (Uncharacterized transposon-derived protein F54H12.3 OS=Araneus ventricosus OX=182803 GN=F54H12.3_86 PE=4 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 5.915e-8
Identity = 30/52 (57.69%), Postives = 44/52 (84.62%), Query Frame = 3 
Query: 2247 NESKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQ 2402
            +E KEFYN +++Q+LK+ KINHYS HS++KA+ VERFNRTL+++L + F H+
Sbjct:   22 DEGKEFYNKQVQQLLKKNKINHYSSHSEHKASVVERFNRTLKNKLFRIFTHR 73
[Close]
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A4Y2T0D2 (Uncharacterized transposon-derived protein F54H12.3 OS=Araneus ventricosus OX=182803 GN=F54H12.3_15 PE=4 SV=1)

HSP 1 Score: 66.6254 bits (161), Expect = 5.970e-8
Identity = 30/52 (57.69%), Postives = 44/52 (84.62%), Query Frame = 3 
Query: 2247 NESKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQ 2402
            +E KEFYN +++Q+LK+ KINHYS HS++KA+ VERFNRTL+++L + F H+
Sbjct:   22 DEGKEFYNKQVQQLLKKNKINHYSSHSEHKASVVERFNRTLKNKLFRIFTHR 73
[Close]
BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Match: A0A3C1P802 (Uncharacterized protein OS=Planktothrix sp. UBA8402 OX=2055759 GN=DCQ63_02380 PE=4 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 8.417e-8
Identity = 30/50 (60.00%), Postives = 39/50 (78.00%), Query Frame = 3 
Query: 2253 SKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQ 2402
             KEFYN  ++ + K+ KI HY+V SQ+KAA VERFNRTLR+RL ++F HQ
Sbjct:  143 GKEFYNKSVQALFKKHKIIHYTVQSQFKAAVVERFNRTLRERLNRFFTHQ 192
[Close]
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000081946.1 (SMESG000081946.1)

HSP 1 Score: 2378.21 bits (6162), Expect = 0.000e+0
Identity = 1380/1431 (96.44%), Postives = 1381/1431 (96.51%), Query Frame = 3 
Query:  126 MLNNNNPAICYQFSKNEPNIKFCSSNPINNAQISNSHYNSLTWNDICSKITNINQEIFFKSITPVSQVQLTKLERLDETKSHLPSYIKKSVLRSKDNKSKFSIKRLNRKLKSENLQXXXXXXXXXXXXXXXXXENMNILPAEVQQSLIQLMPECDKVVNNHEKLNNLFTLSKTSLNNEFFNKALTNFFFKATKKKSTITIESFISNIKTISKSFSENFLSIKKSKDFTDSDLANENSPNPAKKDKISIQFDYDINVNIDKLLNSHFESAVTFINNQINCDNEFQIINQKDEKVFLQKSSIPREDFSDNKDEEYSASFLRQSNLSLALNPESSDFSKSTKYKRKNSESSIAPSPKKRPTRSTAGQLPARLXXXXXXXXXXXXNTQFNHLSLINKSISIRGKYKEKRKSKSNSVTLIKDTQHNKLDCDTILYNLRNKLAKRLQRNCQKNSNDVFLKNESTLNVSSDINCYXXXXXXXXXXXXDRLTFANSPYSKTSQNHFYQSKLKNSFFENQTQNSPQWXXXXXXXXXXXXXXXLSQKNIKAEQDELNGIENFLEDMDSEEMPPPRRTLTVATXXXXXXXXXXXXXXXXXDCDKDNLYDYESKNLNQMVDMAIKXXXXXXXXXXXXXPRENPSDETDEENLQNEFDSFLIDDNNEIDDYHVEIDDKILNYSDDLDELLLTSGNESLLEIIMKDPSAMEIDNENYNSLNNESKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQVQMSNQISPESQNLKGICLTTGVPSTSIVNNSSCVTSTSKFVENLXXXXXXXXNADNPVLLSQTLTSVIQKVSSNIQNSKDVTNIKGSLPNAYLVDGNGLSDALKLIQSLNPGAKVTTQQFYLVNSGPQLILCQTPPTQASSTCPVNSKSQIKSALNXXXXXXXXXXNVXXXXXXXXXXXXXXDDKVATSAYXXXXXXXXXXXXXPILSSTISVLPHFSQINSKSQNLFSLNSSFQNKIITPVTNFSRKLNNNNSSSVTTAIPPGSNTLQQPSIFSNQKSMVTNLNSNTLGIRLQLTQNSQPLSFIQSAQNSVIPAIVNQQLQFLTPQSNNNISLITHPPPMSKLVLLCPNLNCQPIGSDINNPLKTDPQQLIFVSPQKEQTNPIPLTANSAFQVLNGPNIWQQINPNFGTIIGSTSNSNLVLMNPQTISNQSFSFNYQPQSQIITANNLLFMSSNNVSQLHNINSNQKSQTNHNSKIIDTSGPISENNKYDEDNQATMKTQPIKCNSGTXXXXXXXXXXXXXXXXXXXFDEKLSCQSNKSFSETFIDSDREKSVNSPLFHLFTSDFKNSKVNSFQPTKISKFKHLTVDIDSFPPTNSFYQSMISNKIVENCHSIGSKNDDLNIIQSPAPDYDQSDFEIPCVFSSKLQIKRNNLIKKNDKNNTERIFDIKDS 4418
            MLNNNNPAICYQFSKNEPNIKFCSSNPINNAQISNSHYNSLTWNDICSKITNINQEIFFKSITPVSQVQLTKLERLDETKSHLPSYIKKSVLRSKDNKSKFSIKRLNRKLKSENLQLRKSKISALKLKSLISKENMNILPAEVQQSLIQLMPECDKVVNNHEKLNNLFTLSKTSLNNEFFNKALTNFFFKATKKKSTITIESFISNIKTISKSFSENFLSIKKSKDFTDSDLANENSPNPAKKDKISIQFDYDINVNIDKLLNSHFESAVTFINNQINCDNEFQIINQKDEKVFLQKSSIPREDFSDNKDEEYSASFLRQSNLSLALNPESSDFSKSTKYKRKNSESSIAPSPKKRPTRSTAGQLPARLKSISPPSSIQKSNTQFNHLSLINKSISIRGKYKEKRKSKSNSVTLIKDTQHNKLDCDTILYNLRNKLAKRLQRNCQKNSNDVFLKNESTLNVSSDINCYSSKSPCSLSPGSDRLTFANSPYSKTSQNHFYQSKLKNSFFENQTQNSPQWSFSSEFTSQSSVESVLSQKNIKAEQDELNGIENFLEDMDSEEMPPPRRTLTVATMREKMRAKKMAKEGKRKDCDKDNLYDYESKNLNQMVDMAIKHSHSSTMSIMMSMPRENPSDETDEENLQNEFDSFLIDDNNEIDDYHVEIDDKILNYSDDLDELLLTSGNESLLEIIMKDPSAMEIDNENYNSLNNE                                                  +QMSNQISPESQNLKGICLTTGVPSTSIVNNSSCVTSTSKFVENLSISDSSIINADNPVLLSQTLTSVIQKVSSNIQNSKDVTNIKGSLPNAYLVDGNGLSDALKLIQSLNPGAKVTTQQFYLVNSGPQLILCQTPPTQASSTCPVNSKSQIKSALNTTHIISTTSSNVIQSNRNISSFISNNDDKVATSAYISNSKSIVSSNKNPILSSTISVLPHFSQINSKSQNLFSLNSSFQNKIITPVTNFSRKLNNNNSSSVTTAIPPGSNTLQQPSIFSNQKSMVTNLNSNTLGIRLQLTQNSQPLSFIQSAQNSVIPAIVNQQLQFLTPQSNNNISLITHPPPMSKLVLLCPNLNCQPIGSDINNPLKTDPQQLIFVSPQKEQTNPIPLTANSAFQVLNGPNIWQQINPNFGTIIGSTSNSNLVLMNPQTISNQSFSFNYQPQSQIITANNLLFMSSNNVSQLHNINSNQKSQTNHNSKIIDTSGPISENNKYDEDNQATMKTQPIKCNSGTNHSQNSSVNSSSSANSKLSFDEKLSCQSNKSFSETFIDSDREKSVNSPLFHLFTSDFKNSKVNSFQPTKISKFKHLTVDIDSFPPTNSFYQSMISNKIVENCHSIGSKNDDLNIIQSPAPDYDQSDFEIPCVFSSKLQIKRNNLIKKNDKNNTERIFDIKDS
Sbjct:    1 MLNNNNPAICYQFSKNEPNIKFCSSNPINNAQISNSHYNSLTWNDICSKITNINQEIFFKSITPVSQVQLTKLERLDETKSHLPSYIKKSVLRSKDNKSKFSIKRLNRKLKSENLQLRKSKISALKLKSLISKENMNILPAEVQQSLIQLMPECDKVVNNHEKLNNLFTLSKTSLNNEFFNKALTNFFFKATKKKSTITIESFISNIKTISKSFSENFLSIKKSKDFTDSDLANENSPNPAKKDKISIQFDYDINVNIDKLLNSHFESAVTFINNQINCDNEFQIINQKDEKVFLQKSSIPREDFSDNKDEEYSASFLRQSNLSLALNPESSDFSKSTKYKRKNSESSIAPSPKKRPTRSTAGQLPARLKSISPPSSIQKSNTQFNHLSLINKSISIRGKYKEKRKSKSNSVTLIKDTQHNKLDCDTILYNLRNKLAKRLQRNCQKNSNDVFLKNESTLNVSSDINCYSSKSPCSLSPGSDRLTFANSPYSKTSQNHFYQSKLKNSFFENQTQNSPQWSFSSEFTSQSSVESVLSQKNIKAEQDELNGIENFLEDMDSEEMPPPRRTLTVATMREKMRAKKMAKEGKRKDCDKDNLYDYESKNLNQMVDMAIKHSHSSTMSIMMSMPRENPSDETDEENLQNEFDSFLIDDNNEIDDYHVEIDDKILNYSDDLDELLLTSGNESLLEIIMKDPSAMEIDNENYNSLNNE--------------------------------------------------IQMSNQISPESQNLKGICLTTGVPSTSIVNNSSCVTSTSKFVENLSISDSSIINADNPVLLSQTLTSVIQKVSSNIQNSKDVTNIKGSLPNAYLVDGNGLSDALKLIQSLNPGAKVTTQQFYLVNSGPQLILCQTPPTQASSTCPVNSKSQIKSALNTTHIISTTSSNVIQSNRNISSFISNNDDKVATSAYISNSKSIVSSNKNPILSSTISVLPHFSQINSKSQNLFSLNSSFQNKIITPVTNFSRKLNNNNSSSVTTAIPPGSNTLQQPSIFSNQKSMVTNLNSNTLGIRLQLTQNSQPLSFIQSAQNSVIPAIVNQQLQFLTPQSNNNISLITHPPPMSKLVLLCPNLNCQPIGSDINNPLKTDPQQLIFVSPQKEQTNPIPLTANSAFQVLNGPNIWQQINPNFGTIIGSTSNSNLVLMNPQTISNQSFSFNYQPQSQIITANNLLFMSSNNVSQLHNINSNQKSQTNHNSKIIDTSGPISENNKYDEDNQATMKTQPIKCNSGTNHSQNSSVNSSSSANSKLSFDEKLSCQSNKSFSETFIDSDREKSVNSPLFHLFTSDFKNSKVNSFQPTKISKFKHLTVDIDSFPPTNSFYQSMISNKIVENCHSIGSKNDDLNIIQSPAPDYDQSDFEIPCVFSSKLQIKRNNLIKKNDKNNTERIFDIKDS 1381
[Close]
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000055140.1 (SMESG000055140.1)

HSP 1 Score: 103.219 bits (256), Expect = 4.136e-22
Identity = 47/52 (90.38%), Postives = 50/52 (96.15%), Query Frame = 3 
Query: 2247 NESKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQ 2402
            N+ KEFYNSK+KQIL RLKINHYSVHSQYKAAHVERFNRTLRDRLKK+FVHQ
Sbjct:  174 NKGKEFYNSKVKQILDRLKINHYSVHSQYKAAHVERFNRTLRDRLKKYFVHQ 225

HSP 2 Score: 103.219 bits (256), Expect = 4.136e-22
Identity = 47/52 (90.38%), Postives = 50/52 (96.15%), Query Frame = 3 
Query: 2247 NESKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQ 2402
            N+ KEFYNSK+KQIL RLKINHYSVHSQYKAAHVERFNRTLRDRLKK+FVHQ
Sbjct:  423 NKGKEFYNSKVKQILDRLKINHYSVHSQYKAAHVERFNRTLRDRLKKYFVHQ 474
[Close]
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000074857.1 (SMESG000074857.1)

HSP 1 Score: 102.449 bits (254), Expect = 2.435e-21
Identity = 46/50 (92.00%), Postives = 48/50 (96.00%), Query Frame = 3 
Query: 2253 SKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQ 2402
             KEFYNSK+KQIL RLKINHYSVHSQYKAAHVERFNRTLRDRLKK+FVHQ
Sbjct:  147 GKEFYNSKVKQILDRLKINHYSVHSQYKAAHVERFNRTLRDRLKKYFVHQ 196
[Close]
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000053372.1 (SMESG000053372.1)

HSP 1 Score: 102.064 bits (253), Expect = 3.131e-21
Identity = 46/50 (92.00%), Postives = 48/50 (96.00%), Query Frame = 3 
Query: 2253 SKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQ 2402
             KEFYNSK+KQIL RLKINHYSVHSQYKAAHVERFNRTLRDRLKK+FVHQ
Sbjct:  130 GKEFYNSKVKQILDRLKINHYSVHSQYKAAHVERFNRTLRDRLKKYFVHQ 179
[Close]
BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Match: SMESG000029226.1 (SMESG000029226.1)

HSP 1 Score: 102.064 bits (253), Expect = 3.425e-21
Identity = 46/50 (92.00%), Postives = 48/50 (96.00%), Query Frame = 3 
Query: 2253 SKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRDRLKKWFVHQ 2402
             KEFYNSK+KQIL RLKINHYSVHSQYKAAHVERFNRTLRDRLKK+FVHQ
Sbjct:  130 GKEFYNSKVKQILDRLKINHYSVHSQYKAAHVERFNRTLRDRLKKYFVHQ 179
The following BLAST results are available for this feature:
BLAST of Integrase catalytic domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Y2BNX65.471e-857.69Uncharacterized transposon-derived protein F54H12.... [more]
A0A4Y2UGM25.698e-857.69Uncharacterized transposon-derived protein F54H12.... [more]
A0A4Y2HQ685.915e-857.69Uncharacterized transposon-derived protein F54H12.... [more]
A0A4Y2T0D25.970e-857.69Uncharacterized transposon-derived protein F54H12.... [more]
A0A3C1P8028.417e-860.00Uncharacterized protein OS=Planktothrix sp. UBA840... [more]
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Integrase catalytic domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000081946.10.000e+096.44SMESG000081946.1[more]
SMESG000055140.14.136e-2290.38SMESG000055140.1[more]
SMESG000074857.12.435e-2192.00SMESG000074857.1[more]
SMESG000053372.13.131e-2192.00SMESG000053372.1[more]
SMESG000029226.13.425e-2192.00SMESG000029226.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026904 ID=SMED30026904|Name=Integrase catalytic domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=4751bp
TTTTAAAACATCTTAATTTTATATTTATCAAATTATTTTTACTTTTAAAG
AATATTTCATGTGTTCAATTTTAGATATTATAATATATTTAACAATAATT
TAAAAATTTACCAGTCAAATCATTGATGCTTAATAACAACAATCCAGCCA
TTTGCTATCAGTTTTCTAAAAATGAACCTAATATTAAATTTTGCTCTTCA
AATCCTATTAATAACGCTCAAATAAGCAATTCTCACTACAACAGTCTCAC
TTGGAATGATATTTGCTCGAAAATCACAAATATAAATCAAGAAATATTTT
TCAAAAGCATAACTCCAGTTTCGCAAGTACAGCTAACAAAGTTAGAGAGA
TTAGATGAGACAAAATCTCATTTACCTAGTTATATTAAAAAATCAGTATT
ACGTTCAAAAGACAATAAGTCAAAATTTTCAATAAAGCGATTGAATCGAA
AATTAAAATCTGAAAATTTACAACTTAGAAAATCAAAAATATCTGCCTTA
AAGTTAAAGTCCCTGATATCTAAAGAAAATATGAATATTCTACCAGCTGA
GGTCCAACAAAGTCTTATTCAATTAATGCCAGAATGTGATAAAGTTGTTA
ATAATCATGAAAAATTAAATAATTTATTTACTCTTTCTAAAACATCGCTC
AACAATGAATTCTTTAATAAAGCTTTAACGAATTTCTTTTTTAAAGCAAC
AAAGAAAAAATCCACTATAACAATAGAATCCTTTATTAGCAATATCAAAA
CAATTTCTAAAAGCTTTTCTGAAAACTTCTTATCTATAAAAAAATCAAAA
GATTTTACTGATTCAGATTTAGCTAACGAAAACTCACCAAATCCAGCCAA
AAAAGACAAAATATCCATACAATTTGATTACGATATTAATGTTAACATTG
ATAAACTTTTGAACTCGCATTTTGAATCCGCCGTTACATTTATAAATAAT
CAAATAAATTGTGATAATGAATTTCAAATAATAAATCAGAAAGATGAAAA
AGTTTTTTTACAAAAATCTTCGATACCACGTGAAGATTTTTCGGATAATA
AGGATGAAGAATATTCAGCATCTTTCTTACGTCAAAGTAATCTTAGTTTG
GCTTTAAATCCAGAAAGTTCTGATTTTTCAAAAAGTACCAAGTACAAACG
AAAAAACTCCGAGAGTTCAATAGCACCTTCACCAAAAAAACGACCCACTA
GATCAACAGCAGGTCAATTGCCAGCAAGGTTAAAGTCCATTTCACCTCCT
TCGTCAATTCAAAAATCAAACACCCAATTCAATCATTTATCTTTGATAAA
TAAATCTATTTCTATTCGAGGTAAATATAAAGAAAAGCGAAAATCTAAAT
CGAATTCTGTAACTTTAATTAAAGACACACAACATAATAAATTAGACTGT
GATACAATTTTATATAATTTGAGAAATAAATTAGCAAAACGATTACAGCG
GAATTGCCAAAAAAATTCTAATGATGTTTTTTTAAAGAATGAATCTACAC
TAAATGTTTCATCTGATATAAATTGTTATAGTTCTAAATCACCTTGCTCT
TTATCACCCGGGAGTGATAGGTTAACATTTGCCAATTCTCCTTATTCAAA
AACTAGCCAAAATCATTTCTATCAATCTAAATTAAAAAATTCATTTTTTG
AAAATCAGACTCAAAATTCTCCCCAGTGGTCATTTTCATCTGAGTTTACA
TCGCAGTCATCCGTTGAATCAGTGTTGAGTCAAAAAAATATAAAAGCAGA
ACAAGACGAATTAAATGGAATAGAAAATTTCTTGGAAGATATGGATTCAG
AAGAAATGCCACCCCCTAGAAGAACATTAACGGTTGCAACAATGAGAGAA
AAAATGAGAGCTAAAAAAATGGCAAAAGAAGGCAAAAGAAAGGATTGCGA
TAAAGACAACTTGTATGATTATGAAAGTAAAAACCTTAATCAAATGGTTG
ATATGGCCATTAAACATTCACATTCATCAACCATGTCAATAATGATGAGC
ATGCCTCGTGAAAATCCATCTGATGAAACTGATGAAGAGAACTTACAAAA
CGAATTTGACTCATTTCTAATTGATGATAATAATGAAATTGATGATTATC
ATGTGGAAATTGACGATAAAATATTAAATTATTCAGACGATTTAGATGAA
CTACTTTTAACGAGTGGAAATGAAAGCTTACTTGAAATTATTATGAAAGA
TCCTAGTGCAATGGAAATTGATAACGAAAATTATAATTCACTCAACAATG
AAAGTAAAGAGTTTTACAACAGCAAACTTAAGCAAATCCTGAAACGTCTC
AAAATAAATCATTACTCTGTACATTCTCAATACAAAGCCGCTCATGTTGA
GAGATTTAATCGAACATTGAGAGACAGACTAAAGAAATGGTTCGTGCACC
AAGTTCAAATGTCTAATCAAATTTCACCAGAATCACAAAACTTGAAAGGA
ATATGTCTGACGACAGGCGTTCCTTCTACTAGTATTGTTAACAATTCAAG
TTGTGTTACTTCTACCTCAAAATTTGTTGAAAATTTATCTATTTCTGATT
CATCAATTATTAACGCTGATAATCCAGTTTTACTCTCACAAACTCTTACA
TCGGTAATTCAGAAAGTTAGTAGTAATATTCAAAATTCAAAAGATGTTAC
TAACATAAAAGGTTCTTTACCCAATGCATATCTGGTGGATGGCAATGGAT
TATCTGATGCATTAAAATTAATTCAAAGTCTTAACCCTGGAGCAAAAGTA
ACTACACAACAATTTTATTTAGTAAACAGTGGTCCTCAGCTCATCCTTTG
TCAAACACCACCTACTCAAGCTTCTTCAACTTGTCCGGTAAATTCTAAAT
CCCAAATAAAATCGGCACTGAATACAACTCATATAATATCTACCACTTCA
TCAAATGTTATTCAGTCTAATCGAAATATTTCTTCATTTATTTCAAATAA
TGACGATAAAGTTGCAACTTCTGCGTATATATCAAATTCTAAGTCAATCG
TATCTTCTAATAAAAATCCGATTTTGTCTTCCACAATATCTGTTTTACCC
CATTTCTCACAAATTAATTCAAAATCTCAGAATTTATTTTCTTTAAATTC
AAGTTTTCAAAATAAAATTATAACACCTGTCACAAATTTTAGTAGAAAAT
TGAATAATAATAATTCATCATCTGTAACTACTGCCATTCCACCTGGGTCA
AATACTTTGCAACAACCATCAATTTTTTCTAATCAAAAGTCTATGGTTAC
AAATTTAAATTCAAATACTCTTGGAATTCGATTACAGTTAACGCAAAATT
CCCAGCCATTAAGCTTTATTCAGTCAGCTCAGAACTCCGTAATCCCAGCA
ATAGTAAATCAACAACTACAGTTCCTTACACCCCAGTCTAATAATAACAT
ATCTTTAATAACTCACCCACCGCCTATGTCAAAATTAGTTTTACTTTGTC
CAAATTTAAATTGTCAGCCGATTGGATCTGACATTAATAATCCACTGAAA
ACAGATCCTCAACAATTAATTTTTGTGTCTCCACAAAAAGAACAAACAAA
TCCTATTCCACTAACAGCTAATTCTGCATTTCAGGTACTTAATGGACCGA
ATATTTGGCAACAAATTAATCCGAATTTTGGAACCATTATTGGTTCAACT
AGTAATAGCAACTTGGTGCTTATGAATCCTCAAACAATAAGCAATCAGTC
CTTTTCATTTAATTATCAACCTCAATCTCAAATAATTACTGCTAATAATC
TTTTATTTATGTCATCTAACAATGTTAGTCAATTACATAACATAAATAGC
AATCAAAAGTCCCAAACTAATCATAACTCAAAAATTATTGATACTAGTGG
TCCGATATCTGAAAATAATAAGTATGATGAAGATAACCAGGCTACTATGA
AAACGCAGCCTATAAAATGTAATTCAGGTACAAACCATAGTCAAAACAGT
TCAGTCAATTCATCATCATCAGCTAATTCCAAATTATCTTTTGATGAAAA
ATTAAGCTGCCAATCGAATAAATCTTTTTCAGAAACTTTCATTGATTCAG
ATCGTGAAAAATCCGTTAATTCCCCATTATTTCATTTATTTACTTCTGAT
TTTAAAAACTCAAAAGTTAATTCTTTTCAGCCCACAAAAATAAGTAAATT
CAAACATTTGACTGTCGATATTGATTCATTTCCCCCAACTAATTCTTTTT
ATCAGAGTATGATTTCAAACAAAATTGTTGAAAACTGTCATTCTATAGGT
TCAAAGAATGATGATTTAAATATCATTCAGTCTCCAGCACCAGATTATGA
TCAGTCTGATTTCGAAATACCTTGTGTATTTTCGTCAAAATTGCAAATAA
AAAGGAATAATTTAATCAAAAAAAATGATAAAAATAATACCGAAAGAATT
TTCGATATCAAAGATTCTTGAATTTTAAATATTATTATTATGTAATATGT
ATTTCTTAATTTTTAAAATAAAATAATAGTTAATTATGACAGTAAAGATT
TAAAATATTAAGTTAAACGAGTTGTGATATATTATTAGTCAGAAATATGA
TTTATGTAAATTATTTTTTTAATATTAATGTTATCTTTTATGATGTTTTC
TTTCCCAATAAGGTGTTATTTAAGTTTTTAACAGAAAGTCATAGACAAGG
TTGAAGTAATCGGTAATTCTATTATTTTATTATTCTTATTTTGTACATAA
AACAATTTTATTTTTATTATAACTTTGTATATTTATTGTGGTATTTACGA
C
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protein sequence of SMED30026904-orf-1

>SMED30026904-orf-1 ID=SMED30026904-orf-1|Name=SMED30026904-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1432bp
MLNNNNPAICYQFSKNEPNIKFCSSNPINNAQISNSHYNSLTWNDICSKI
TNINQEIFFKSITPVSQVQLTKLERLDETKSHLPSYIKKSVLRSKDNKSK
FSIKRLNRKLKSENLQLRKSKISALKLKSLISKENMNILPAEVQQSLIQL
MPECDKVVNNHEKLNNLFTLSKTSLNNEFFNKALTNFFFKATKKKSTITI
ESFISNIKTISKSFSENFLSIKKSKDFTDSDLANENSPNPAKKDKISIQF
DYDINVNIDKLLNSHFESAVTFINNQINCDNEFQIINQKDEKVFLQKSSI
PREDFSDNKDEEYSASFLRQSNLSLALNPESSDFSKSTKYKRKNSESSIA
PSPKKRPTRSTAGQLPARLKSISPPSSIQKSNTQFNHLSLINKSISIRGK
YKEKRKSKSNSVTLIKDTQHNKLDCDTILYNLRNKLAKRLQRNCQKNSND
VFLKNESTLNVSSDINCYSSKSPCSLSPGSDRLTFANSPYSKTSQNHFYQ
SKLKNSFFENQTQNSPQWSFSSEFTSQSSVESVLSQKNIKAEQDELNGIE
NFLEDMDSEEMPPPRRTLTVATMREKMRAKKMAKEGKRKDCDKDNLYDYE
SKNLNQMVDMAIKHSHSSTMSIMMSMPRENPSDETDEENLQNEFDSFLID
DNNEIDDYHVEIDDKILNYSDDLDELLLTSGNESLLEIIMKDPSAMEIDN
ENYNSLNNESKEFYNSKLKQILKRLKINHYSVHSQYKAAHVERFNRTLRD
RLKKWFVHQVQMSNQISPESQNLKGICLTTGVPSTSIVNNSSCVTSTSKF
VENLSISDSSIINADNPVLLSQTLTSVIQKVSSNIQNSKDVTNIKGSLPN
AYLVDGNGLSDALKLIQSLNPGAKVTTQQFYLVNSGPQLILCQTPPTQAS
STCPVNSKSQIKSALNTTHIISTTSSNVIQSNRNISSFISNNDDKVATSA
YISNSKSIVSSNKNPILSSTISVLPHFSQINSKSQNLFSLNSSFQNKIIT
PVTNFSRKLNNNNSSSVTTAIPPGSNTLQQPSIFSNQKSMVTNLNSNTLG
IRLQLTQNSQPLSFIQSAQNSVIPAIVNQQLQFLTPQSNNNISLITHPPP
MSKLVLLCPNLNCQPIGSDINNPLKTDPQQLIFVSPQKEQTNPIPLTANS
AFQVLNGPNIWQQINPNFGTIIGSTSNSNLVLMNPQTISNQSFSFNYQPQ
SQIITANNLLFMSSNNVSQLHNINSNQKSQTNHNSKIIDTSGPISENNKY
DEDNQATMKTQPIKCNSGTNHSQNSSVNSSSSANSKLSFDEKLSCQSNKS
FSETFIDSDREKSVNSPLFHLFTSDFKNSKVNSFQPTKISKFKHLTVDID
SFPPTNSFYQSMISNKIVENCHSIGSKNDDLNIIQSPAPDYDQSDFEIPC
VFSSKLQIKRNNLIKKNDKNNTERIFDIKDS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0015074DNA integration
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR012337RNaseH-like_sf
IPR028020ASXH
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding