SWIM-type domain-containing protein

Overview


Name	SWIM-type domain-containing protein
Smed ID	SMED30026870
Length (bp)	5032

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SWIM-type domain-containing protein (SMED30026870) t-SNE clustered cells

Violin plots show distribution of expression levels for SWIM-type domain-containing protein (SMED30026870) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SWIM-type domain-containing protein (SMED30026870) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SWIM-type domain-containing protein (SMED30026870) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30026870

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 13

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30026870	h1SMcG0002848	Contig3125	GPL15192	PMID:23079596 Forsthoefel et al., 2012
pharynx	SMED30026870	h1SMcG0002848	dd_Smed_v4_5330_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30026870	h1SMcG0002848	dd_Smed_v4_5330_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30026870	h1SMcG0002848	dd_Smed_v4_5330_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30026870	h1SMcG0002848	dd_Smed_v4_5330_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30026870	h1SMcG0002848	dd_Smed_v4_5330_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30026870	h1SMcG0002848	dd_Smed_v4_5330_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30026870	h1SMcG0002848	dd_Smed_v4_5330_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30026870	h1SMcG0002848	dd_Smed_v4_5330_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30026870	h1SMcG0002848	dd_Smed_v4_5330_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30026870	h1SMcG0002848	Contig4116	GPL15192	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30026870	h1SMcG0021709	Contig4116	GPL15192	PMID:29674431 Fincher et al., 2018
epidermis	SMED30026870	h1SMcG0002848	dd_Smed_v4_5330_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of SWIM-type domain-containing protein vs. Ensembl Human
Match: KY (kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:HGNC:26576])

HSP 1 Score: 123.635 bits (309), Expect = 5.027e-28
Identity = 110/417 (26.38%), Postives = 171/417 (41.01%), Query Frame = 1

Query: 3241 ELVLYLTKDCSKDVEKVRAIFRWIT---TYDIKSV---NFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGV---------LGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIY 4446
            ELV  L ++   D+E+VRAI+ WI     YDI +    +     P D    +LR  K        LF RMCR AG+ C  + GYSKG GY+ G +      F + W AVY+ G W  V+  WG             SG + + TS+  +L N     EFYFLT     I +HFPD K WQLL  P +L QF      KS F+N  +        +++T  GK TV I           L  + +  +L        L    + +   P   G   L I+   +    D       + + C+           + D+GV         +G +  S+ +GI+     DP ++        ++ ++  G+ V   +   D  G  +       + Q   + +++  ++ P  G + L I+
Sbjct:  149 ELVSDLLQEAHTDLERVRAIWIWICHHIEYDIAAAQEKDRQAFKPTD----ILRTQKTNCDGYAGLFERMCRLAGVQCMTVPGYSKGFGYQTGQSFSGE--FDHAWNAVYLEGRWHLVDSTWG-------------SGLVDTITSKFTFLYN-----EFYFLTHPALFIEDHFPDNKNWQLLKPPQSLRQFENNMYHKSEFYNKGMLSAHPETSMIRTVNGKATVTIESCAPTLFMFMLNGKQEHGLLS-------LRKNGMKLEVYPPTMGTHKLQIFAKGN---SDIYSSVLEYTLKCN-----------YVDMGVQLPAELHQPVGPSWFSEQMGIMKPSHPDP-IIHTSDGRCSISFSVEEGINVLASLHGDD--GPITEETQRRYIFQLHREKQTELKVQLPHAGKFALKIF 517

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BLAST of SWIM-type domain-containing protein vs. Ensembl Human
Match: KY (kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:HGNC:26576])

HSP 1 Score: 123.635 bits (309), Expect = 5.200e-28
Identity = 81/227 (35.68%), Postives = 109/227 (48.02%), Query Frame = 1

Query: 3241 ELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDT------LVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKI 3903
            ELV  L ++   D+E+VRAI+ WI  +    + +D AA  +          +LR  K        LF RMCR AG+ C  + GYSKG GY+ G +      F + W AVY+ G W  V+  WG             SG + + TS+  +L N     EFYFLT     I +HFPD K WQLL  P +L QF      KS F+N  +        +++T  GK TV I
Sbjct:  170 ELVSDLLQEAHTDLERVRAIWIWICHH----IEYDIAAAQEKDRQAFKPTDILRTQKTNCDGYAGLFERMCRLAGVQCMTVPGYSKGFGYQTGQSFSGE--FDHAWNAVYLEGRWHLVDSTWG-------------SGLVDTITSKFTFLYN-----EFYFLTHPALFIEDHFPDNKNWQLLKPPQSLRQFENNMYHKSEFYNKGMLSAHPETSMIRTVNGKATVTI 372

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BLAST of SWIM-type domain-containing protein vs. Ensembl Human
Match: KY (kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:HGNC:26576])

HSP 1 Score: 82.4185 bits (202), Expect = 4.858e-16
Identity = 47/124 (37.90%), Postives = 63/124 (50.81%), Query Frame = 1

Query: 3241 ELVLYLTKDCSKDVEKVRAIFRWIT---TYDIKSV---NFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGA 3594
            ELV  L ++   D+E+VRAI+ WI     YDI +    +     P D    +LR  K        LF RMCR AG+ C  + GYSKG GY+ G +      F + W AVY+ G W  V+  WG+
Sbjct:  170 ELVSDLLQEAHTDLERVRAIWIWICHHIEYDIAAAQEKDRQAFKPTD----ILRTQKTNCDGYAGLFERMCRLAGVQCMTVPGYSKGFGYQTGQSFSGE--FDHAWNAVYLEGRWHLVDSTWGS 287

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BLAST of SWIM-type domain-containing protein vs. Ensembl Celegans
Match: ltd-1 (Lim and Transglutaminase Domain [Source:UniProtKB/TrEMBL;Acc:A0A131MD24])

HSP 1 Score: 203.371 bits (516), Expect = 7.347e-56
Identity = 143/449 (31.85%), Postives = 213/449 (47.44%), Query Frame = 1

Query: 3190 VDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRH---QELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAE--VLQTKKGKVTVKINMPQA-----VGVSVKLENRTDGTILRGLTLARIL------DGQMIVVTASPSQPGKFYLSIYVNEDWKSE------DNMEMACSFQVHCSEHNYDRLVTGRFPDV--GVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQY-HLRFPIEGFYCLTIYAGVDD 4461
            +D + I     E  +FT+L+  L+     DV+  RAI+RWIT  ++ ++ FD +  NDT +G+LR IK G  S + LF R+C YAG+HC  I G+SK AGY+PG +  D+R FRN W AV++ G+WRFV CNWGAR+L +      E  + G L            +   D+ YF+TD+++ I+E FP    WQLL RP++L QF  +P V+S FF  NLSF  N  E  V   K G  ++ I +P          ++K  +  + TI  G++L R +      D     V A  ++P    L I+ N               +  C F+V C      +++    P+   G  G   A++  G++     D  +       ++  +  RP       +       +    C   AL     +G   Y  + FP EG Y L IY   DD
Sbjct:   44 IDEVAIHCARNEVASFTDLIRTLSSGARSDVDVARAIYRWITIKNLNTMIFDDSIQNDTPMGLLRGIKYGTESYHVLFKRLCSYAGLHCVVIKGFSKSAGYQPGYSFDDHR-FRNTWNAVFLDGSWRFVQCNWGARHLVNAKDGSHEAKTDGNL------------RYEYDDHYFMTDSEEFIYEFFPSDHAWQLLPRPLSLLQFERIPFVRSLFFKYNLSFIDNKLESTVYTDKSGAASISIRLPPKGDSLIFHYNLKFFDSEENTI-SGMSLKRFVMQSVTEDVVTFRVHAPSTRP--LLLDIFANSVSSGAYLTGQPIKFKSVCKFKVVCESL---QVIMVPLPECASGEWGPAKATRLFGLLPISHPDAIINTGRYVEIRFRMT-RPLSEFVASLHRNRTDDRALQACTRSAL-----KGDMVYIQIEFPGEGQYGLDIYTRQDD 467

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BLAST of SWIM-type domain-containing protein vs. Ensembl Celegans
Match: ltd-1 (Lim and Transglutaminase Domain [Source:UniProtKB/TrEMBL;Acc:A0A131MD24])

HSP 1 Score: 203.756 bits (517), Expect = 3.711e-54
Identity = 144/447 (32.21%), Postives = 220/447 (49.22%), Query Frame = 1

Query: 3190 VDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAE--VLQTKKGKVTVKINMPQA-----VGVSVKLENRTDGTILRGLTLARIL------DGQMIVVTASPSQPGKFYLSIYVNEDWKSE------DNMEMACSFQVHCSEHNYDRLVTGRFPDV--GVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNS-APCDSYALLQYQSQGRSQY-HLRFPIEGFYCLTIYAGVDD 4461
            +D + I     E  +FT+L+  L+     DV+  RAI+RWIT  ++ ++ FD +  NDT +G+LR IK G  S + LF R+C YAG+HC  I G+SK AGY+PG +  D+R FRN W AV++ G+WRFV CNWGAR+L +        G+  ++T  +   E     D+ YF+TD+++ I+E FP    WQLL RP++L QF  +P V+S FF  NLSF  N  E  V   K G  ++ I +P          ++K  +  + TI  G++L R +      D     V A  ++P    L I+ N               +  C F+V C      +++    P+   G  G   A++  G++  P   P  + +    +++   +   L      +  +R+   +   C   AL     +G   Y  + FP EG Y L IY   DD
Sbjct:  278 IDEVAIHCARNEVASFTDLIRTLSSGARSDVDVARAIYRWITIKNLNTMIFDDSIQNDTPMGLLRGIKYGTESYHVLFKRLCSYAGLHCVVIKGFSKSAGYQPGYSFDDHR-FRNTWNAVFLDGSWRFVQCNWGARHLVN-----AKDGSHEAKTDGNLRYE----YDDHYFMTDSEEFIYEFFPSDHAWQLLPRPLSLLQFERIPFVRSLFFKYNLSFIDNKLESTVYTDKSGAASISIRLPPKGDSLIFHYNLKFFDSEENTI-SGMSLKRFVMQSVTEDVVTFRVHAPSTRP--LLLDIFANSVSSGAYLTGQPIKFKSVCKFKVVCESL---QVIMVPLPECASGEWGPAKATRLFGLL--PISHPDAIINTGRYVEIRFRMTRPLSEFVASLHRNRTDDRALQACTRSAL-----KGDMVYIQIEFPGEGQYGLDIYTRQDD 701

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BLAST of SWIM-type domain-containing protein vs. Ensembl Fly
Match: Hil (gene:FBgn0050147 transcript:FBtr0086255)

HSP 1 Score: 236.498 bits (602), Expect = 2.665e-64
Identity = 155/447 (34.68%), Postives = 224/447 (50.11%), Query Frame = 1

Query: 3172 PESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFK-RNYAEVLQT-KKGKVTVKINMPQAVGVSVKL-----------ENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVN----EDWKSEDNMEM--ACSFQVHCSEHNYDRLVTGRFPDV--GVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYA 4449
            P     VD + I V   +  TFT+LV  L   C+ D+EK R IFRWIT  ++ +++FD     DT +G+LR IK G  S + LF R+C YAG+HC  I GYSK AGY+PG+  +D+R FRN W AVYVAGAWRFV CNWGAR+L +  +E P  G   + + + +Y       D+ YFLTD ++ I+E +P ++ WQLL RPITL +F  LP V+S FF   L F    Y  V+ T   G  TV+I MP  +   +             E   DG  L+   +  ++ G ++         G F L I+ N    +++ + + M+    C F++ C E    + V    PD   G  G T A++  G+I     DP +     +   L++  R    +   M +  ++G        Y +          + + FP EG Y L IY 
Sbjct:  349 PIEFEDVDRIAISVAQEDQKTFTDLVRQLVGRCTTDIEKARTIFRWITVKNLNAMHFDDDLRGDTPMGLLRGIKYGTESYHVLFKRLCSYAGLHCVVIKGYSKSAGYQPGVKFQDSR-FRNSWNAVYVAGAWRFVQCNWGARHLVNA-KEAPKQGRGKNDSLRYEY-------DDHYFLTDPREFIYEFYPLQEEWQLLKRPITLREFENLPFVRSLFFRYGLHFADEGYGAVVFTDDTGAATVRIAMPTDMQSCLIFHYNLKFYDSDEELSYDGVSLKRFVMQSVI-GNIVAFRVHAPCSGAFLLDIFANAVTPQEYLTGEPMKFKSVCKFKICCEEL---QTVMVPLPDCASGEWGPTKATRLFGLIPITHQDPLIF----AGRSLDLQFRMSRPLTDFMATLHKNGIEEKKLAKY-VTHSTLDDIVTFIINFPEEGQYGLDIYT 777

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BLAST of SWIM-type domain-containing protein vs. Ensembl Fly
Match: Hil (gene:FBgn0050147 transcript:FBtr0086256)

HSP 1 Score: 236.498 bits (602), Expect = 2.665e-64
Identity = 155/447 (34.68%), Postives = 224/447 (50.11%), Query Frame = 1

Query: 3172 PESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFK-RNYAEVLQT-KKGKVTVKINMPQAVGVSVKL-----------ENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVN----EDWKSEDNMEM--ACSFQVHCSEHNYDRLVTGRFPDV--GVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYA 4449
            P     VD + I V   +  TFT+LV  L   C+ D+EK R IFRWIT  ++ +++FD     DT +G+LR IK G  S + LF R+C YAG+HC  I GYSK AGY+PG+  +D+R FRN W AVYVAGAWRFV CNWGAR+L +  +E P  G   + + + +Y       D+ YFLTD ++ I+E +P ++ WQLL RPITL +F  LP V+S FF   L F    Y  V+ T   G  TV+I MP  +   +             E   DG  L+   +  ++ G ++         G F L I+ N    +++ + + M+    C F++ C E    + V    PD   G  G T A++  G+I     DP +     +   L++  R    +   M +  ++G        Y +          + + FP EG Y L IY 
Sbjct:  349 PIEFEDVDRIAISVAQEDQKTFTDLVRQLVGRCTTDIEKARTIFRWITVKNLNAMHFDDDLRGDTPMGLLRGIKYGTESYHVLFKRLCSYAGLHCVVIKGYSKSAGYQPGVKFQDSR-FRNSWNAVYVAGAWRFVQCNWGARHLVNA-KEAPKQGRGKNDSLRYEY-------DDHYFLTDPREFIYEFYPLQEEWQLLKRPITLREFENLPFVRSLFFRYGLHFADEGYGAVVFTDDTGAATVRIAMPTDMQSCLIFHYNLKFYDSDEELSYDGVSLKRFVMQSVI-GNIVAFRVHAPCSGAFLLDIFANAVTPQEYLTGEPMKFKSVCKFKICCEEL---QTVMVPLPDCASGEWGPTKATRLFGLIPITHQDPLIF----AGRSLDLQFRMSRPLTDFMATLHKNGIEEKKLAKY-VTHSTLDDIVTFIINFPEEGQYGLDIYT 777

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BLAST of SWIM-type domain-containing protein vs. Ensembl Zebrafish
Match: ky (kyphoscoliosis peptidase [Source:ZFIN;Acc:ZDB-GENE-090313-64])

HSP 1 Score: 106.686 bits (265), Expect = 2.639e-23
Identity = 81/303 (26.73%), Postives = 138/303 (45.54%), Query Frame = 1

Query: 3256 LTKDCSKDVEKVRAIFRWIT---TYDIKSVNFDPAAPNDTLVGVLRAIK--CGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTAS---------PSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHC 4122
            +T+    +VEK+RAI+ W+     YDI+      +    +L  V+R  K  C   SN  L   MCR  GI C  +SGYSKG GY+   ++ +     + W AV++ G W  ++  WGA  +  +           S+T   +Y       D+FYFLT+  + I  HFPD + WQLLT PI++ +F   P+  S F+   L+          T+ G+  V ++  + +  S ++      T   G      +D    +++ +         PS+PG + + ++   + +    +   CS ++ C
Sbjct:   54 VTEVARNEVEKLRAIWIWLCHNIEYDIEGY-LGLSQKICSLDEVIRNGKGVCSGYSN--LCVEMCREVGIECVEVSGYSKGIGYQARHSLAEE-CSDHEWNAVFIDGQWWLLDACWGAGTVDMK-----------SKTFVKRY-------DDFYFLTEPSEFINSHFPDDQTWQLLTTPISIQEFEMRPLRTSAFYQLGLTLIHPKQYKTITEDGEAIVSVSSSRLLTFSYEMRQHDPQT---GALKQEEVDSSCGLLSVTHQGMKLRLLPSEPGTYEVKLFARREGEP-GALRWVCSLELEC 330

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BLAST of SWIM-type domain-containing protein vs. Ensembl Zebrafish
Match: ky (kyphoscoliosis peptidase [Source:ZFIN;Acc:ZDB-GENE-090313-64])

HSP 1 Score: 97.4413 bits (241), Expect = 4.905e-20
Identity = 66/252 (26.19%), Postives = 113/252 (44.84%), Query Frame = 1

Query: 3394 CGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTAS---------PSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHC 4122
            C   SN  L   MCR  GI C  +SGYSKG GY+   ++ +     + W AV++ G W  ++  WGA  +  +           S+T   +Y       D+FYFLT+  + I  HFPD + WQLLT PI++ +F   P+  S F+   L+          T+ G+  V ++  + +  S ++      T   G      +D    +++ +         PS+PG + + ++   + +    +   CS ++ C
Sbjct:   43 CSGYSN--LCVEMCREVGIECVEVSGYSKGIGYQARHSLAE-ECSDHEWNAVFIDGQWWLLDACWGAGTVDMK-----------SKTFVKRY-------DDFYFLTEPSEFINSHFPDDQTWQLLTTPISIQEFEMRPLRTSAFYQLGLTLIHPKQYKTITEDGEAIVSVSSSRLLTFSYEMRQHDPQT---GALKQEEVDSSCGLLSVTHQGMKLRLLPSEPGTYEVKLFARREGEP-GALRWVCSLELEC 269

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BLAST of SWIM-type domain-containing protein vs. Ensembl Xenopus
Match: cnpy1 (canopy FGF signaling regulator 1 [Source:Xenbase;Acc:XB-GENE-981809])

HSP 1 Score: 134.035 bits (336), Expect = 1.701e-31
Identity = 138/514 (26.85%), Postives = 216/514 (42.02%), Query Frame = 1

Query: 3223 EPTTFTELVLYLTKDCSKDVEKVRAIFRWIT---TYDIKSV---NFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQ--TKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTG-RFPDV--GVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPC-DSYALLQYQSQGRSQYHLRFPIE-GFYCLTIYAGVDDPDLPDTEPMECIYRLLIDCKRAQERIPPFPRQTSRW-VGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLW 4722
            + +T  +LV  L +    D+EKVRAI+ WI     YD+  +   +     PN TL+    A +        LF  MC +AGI C  I G+SKG  Y  G          + W AV++   W  ++  WGA +  S                       K R +EFYFLT     I EHFPD + WQLL  P+++ QF       S F+NA L+   +Y E LQ  T  GK T  I        S  L N+T+   +  LT     +G  + V   P+  G+  L +Y       +++ +    + +HC       + TG R P     ++G +  ++  G + +   DP +++ +     +   +     V   + S      N  P  ++  +LQ     R ++ +  P + G Y L I       D  +     C Y  L+ C     R P FP + + W   + L+EPL   L  N+P RF+I A   +  +V++       L ++S+G W
Sbjct:   99 KASTVGQLVSSLIRMARTDLEKVRAIWTWICHHIEYDLDGMEDKSKRSGDPNQTLLSGKGACE----GYAGLFENMCSHAGIQCLKIGGFSKGFCYTTGQTFSGET--NHAWNAVFLNKRWHLLDTTWGAGFANSSTNSF------------------KFRYNEFYFLTHPALFIEEHFPDNQNWQLLQVPLSMKQFEGNLCRNSSFYNAGLT--ASYPETLQVETVNGKATFSIEGHSPALFSFTL-NKTEKPGIMTLT----KNGMQLDVY--PTVTGRHKLELYTKPFNTVKESYDKVVEYILHCGS-----VDTGFRIPKELDPIVGPSWLTEMKGFLQHLCSDP-IIYTQDGCCSVGFTLAKKAIVLATLHS-----DNIKPGYENRYVLQTLRGNRVEFKIHLPQQAGTYVLKI-CTKKKSDPGNMYDYACNY--LLCCSNPSVRWPFFPMRYNAWDSTYELIEPLNGILPANSPVRFKIKARGLA--AVLVKALNICPLTLNSDGFW 563

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BLAST of SWIM-type domain-containing protein vs. Ensembl Xenopus
Match: lmbr1 (limb development membrane protein 1 [Source:Xenbase;Acc:XB-GENE-981846])

HSP 1 Score: 129.798 bits (325), Expect = 2.478e-30
Identity = 144/548 (26.28%), Postives = 234/548 (42.70%), Query Frame = 1

Query: 3151 LKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWIT------TYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTEPMECIYRLLIDCKRAQERIPPFPRQTSRWVG-FRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVNTG--QELENLSV 4767
            LKS  I  ++   +D    +V     TT   LV  L ++   D+EK RAI+ WI       T  +K ++     PND    VLR  K      + LF  MC  AG+ C+ +SGYSKG  Y+ G     +      W  VY+ G+W  ++  WG            S  T+ +    + Y       +EFYFLT     I +HFP++ + QLL   ++L QF  L   K  F+   L         ++T KGKVT  +     +     L N+T+   L  LT         + +   P + G+  L I+   +  SE   +    ++V C   + +  +      +  +G +  S+  G+      DP V++ E     ++ A++  L +   + S +   Q ++      + Q Q +   ++ +R P  G Y L +   V DP+  DT   +C Y  +I C       P FP     W   + L+ PL   L  N+   F++     + VSV    + +  L+++  G W+G  +TG  QEL N++V
Sbjct:   25 LKSLQIDLKAFEKLDAYAAKV-----TTVDLLVKELIRNTHSDLEKTRAIWIWICHHIEYDTEGLKDLSQVSCDPND----VLRTRKGVCAGYSSLFESMCSIAGVKCKSMSGYSKGGRYKTGQTFSGDSTHE--WNMVYLEGSWHLLDSTWG------------SVATVSTFCFLNLY-------NEFYFLTHPALFIEDHFPEENKHQLLEPCVSLKQFEKLN-RKCYFYKMGLLSSWPDTVTVETVKGKVTFTLEGRHHLLFLFHL-NKTETPGLMQLT------EHGMKLDVYPQKTGEQILQIFAKRE-DSEGVYDWILDYKVICKSVDTNMKIPKCL--MNPVGPSWLSEKAGLFQPSHQDP-VIYTEDGCCTVSFALKGKLSIFATLDSSEI--QMTSDMKHRHIFQTQRENDVEFKVRLPTSGTYVLCV--NVKDPN-GDTYTSQCKY--VIFCTNHTVHWPQFPLVYGTWAKHYELLGPLDGILPENSNISFKLRVPDVTEVSVRGGKSSF-PLSLTPQGYWEGMCSTGGNQEL-NVTV 521

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BLAST of SWIM-type domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000026106.1 (kyphoscoliosis peptidase-like [Source:NCBI gene;Acc:100486532])

HSP 1 Score: 59.3066 bits (142), Expect = 4.207e-9
Identity = 47/156 (30.13%), Postives = 71/156 (45.51%), Query Frame = 1

Query: 3163 IISPESLIHVDNMVIEVML---LEPTTFTELVLYLTKDCSKDVEKVRAIFRWIT---TYDIKS-VNFDPAA--PNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAI---KDNRMFRNVWTAVYVAGAWRFVNCNWGA 3594
            + S  +  H+DN VI        +  +  E V  +T +    +EK+RAI+ W+     YD++  + F      P D L  + + +  G      LF  MCR  GI C+ ISGYS+   Y  G++    K N M    W AV +   W  ++  WGA
Sbjct:   26 LFSSVTFTHIDNHVINWSGQNNCQALSIQETVRGITAEARNHLEKIRAIWIWLCHNIRYDVEGYLGFSQKVYRPEDVLA-LGKGVCSGYAG---LFKEMCREIGIGCKEISGYSRTTEYSDGLSFHRTKSNHM----WNAVQLDTDWHLLDACWGA 173

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BLAST of SWIM-type domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000026111.1 (kyphoscoliosis peptidase-like [Source:NCBI gene;Acc:100486532])

HSP 1 Score: 56.225 bits (134), Expect = 5.101e-7
Identity = 38/129 (29.46%), Postives = 61/129 (47.29%), Query Frame = 1

Query: 3232 TFTELVLYLTKDCSKDVEKVRAIFRWITT-----YDIKS-VNFDPAA--PNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGA 3594
            +  E V  +T +    +EK+RAI+ W+       YD++  + F      P D L  + + +  G      LF  MCR  GI C+ ISGYS+   Y  G++    +   ++W AV +   W  ++  WGA
Sbjct:  129 SIQETVRGITAEARNHLEKIRAIWIWLCHNISEWYDVEGYLGFSQKVYRPEDVLA-LGKGVCSGYAG---LFKEMCREIGIGCKEISGYSRTTEYSDGLSFHRTKS-NHMWNAVQLDTDWHLLDACWGA 252

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BLAST of SWIM-type domain-containing protein vs. Ensembl Mouse
Match: Ky (kyphoscoliosis peptidase [Source:MGI Symbol;Acc:MGI:96709])

HSP 1 Score: 124.02 bits (310), Expect = 3.102e-28
Identity = 81/231 (35.06%), Postives = 111/231 (48.05%), Query Frame = 1

Query: 3229 TTFTELVLYLTKDCSKDVEKVRAIFRWIT---TYDIKSV---NFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKI 3903
            +   ELV  L ++   D+E+VRAI+ WI     YD+++    +     P D    +LR  K        LF RMCR AG+ C  + GYSKG GY+ G +      F + W AVY+ G W  V+  WG             SG + + TS+  +L N     EFYFLT     I +HFPD K WQLL  P +L QF      KS F+N  +        +++T  GK T+ I
Sbjct:  166 SGLNELVSDLLQEAHSDLERVRAIWIWICHHIEYDVEAAQEKDRQAFKPTD----ILRTQKTNCDGYAGLFERMCRVAGVQCVTVPGYSKGFGYQTGQSFSGE--FDHAWNAVYLEGRWHLVDSTWG-------------SGLVDTTTSKFTFLYN-----EFYFLTHPALFIEDHFPDNKNWQLLKPPQSLRQFENSMYHKSEFYNKGMLSAHPETSMIRTVNGKATITI 372

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BLAST of SWIM-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q0E908|HIL_DROME (Hillarin OS=Drosophila melanogaster OX=7227 GN=Hil PE=1 SV=1)

HSP 1 Score: 236.498 bits (602), Expect = 2.671e-63
Identity = 155/447 (34.68%), Postives = 224/447 (50.11%), Query Frame = 1

Query: 3172 PESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFK-RNYAEVLQT-KKGKVTVKINMPQAVGVSVKL-----------ENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVN----EDWKSEDNMEM--ACSFQVHCSEHNYDRLVTGRFPDV--GVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYA 4449
            P     VD + I V   +  TFT+LV  L   C+ D+EK R IFRWIT  ++ +++FD     DT +G+LR IK G  S + LF R+C YAG+HC  I GYSK AGY+PG+  +D+R FRN W AVYVAGAWRFV CNWGAR+L +  +E P  G   + + + +Y       D+ YFLTD ++ I+E +P ++ WQLL RPITL +F  LP V+S FF   L F    Y  V+ T   G  TV+I MP  +   +             E   DG  L+   +  ++ G ++         G F L I+ N    +++ + + M+    C F++ C E    + V    PD   G  G T A++  G+I     DP +     +   L++  R    +   M +  ++G        Y +          + + FP EG Y L IY 
Sbjct:  349 PIEFEDVDRIAISVAQEDQKTFTDLVRQLVGRCTTDIEKARTIFRWITVKNLNAMHFDDDLRGDTPMGLLRGIKYGTESYHVLFKRLCSYAGLHCVVIKGYSKSAGYQPGVKFQDSR-FRNSWNAVYVAGAWRFVQCNWGARHLVNA-KEAPKQGRGKNDSLRYEY-------DDHYFLTDPREFIYEFYPLQEEWQLLKRPITLREFENLPFVRSLFFRYGLHFADEGYGAVVFTDDTGAATVRIAMPTDMQSCLIFHYNLKFYDSDEELSYDGVSLKRFVMQSVI-GNIVAFRVHAPCSGAFLLDIFANAVTPQEYLTGEPMKFKSVCKFKICCEEL---QTVMVPLPDCASGEWGPTKATRLFGLIPITHQDPLIF----AGRSLDLQFRMSRPLTDFMATLHKNGIEEKKLAKY-VTHSTLDDIVTFIINFPEEGQYGLDIYT 777

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BLAST of SWIM-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8NBH2|KY_HUMAN (Kyphoscoliosis peptidase OS=Homo sapiens OX=9606 GN=KY PE=1 SV=2)

HSP 1 Score: 126.716 bits (317), Expect = 1.515e-28
Identity = 110/420 (26.19%), Postives = 172/420 (40.95%), Query Frame = 1

Query: 3241 ELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDT------LVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGV---------LGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGV 4455
            ELV  L ++   D+E+VRAI+ WI  +    + +D AA  +          +LR  K        LF RMCR AG+ C  + GYSKG GY+ G +      F + W AVY+ G W  V+  WG             SG + + TS+  +L N     EFYFLT     I +HFPD K WQLL  P +L QF      KS F+N  +        +++T  GK TV I           L  + +  +L        L    + +   P   G   L I+   +    D       + + C+           + D+GV         +G +  S+ +GI+     DP ++        ++ ++  G+ V   +   D  G  +       + Q   + +++  ++ P  G + L IY  V
Sbjct:  170 ELVSDLLQEAHTDLERVRAIWIWICHH----IEYDIAAAQEKDRQAFKPTDILRTQKTNCDGYAGLFERMCRLAGVQCMTVPGYSKGFGYQTGQSFSGE--FDHAWNAVYLEGRWHLVDSTWG-------------SGLVDTITSKFTFLYN-----EFYFLTHPALFIEDHFPDNKNWQLLKPPQSLRQFENNMYHKSEFYNKGMLSAHPETSMIRTVNGKATVTIESCAPTLFMFMLNGKQEHGLLS-------LRKNGMKLEVYPPTMGTHKLQIFAKGN---SDIYSSVLEYTLKCN-----------YVDMGVQLPAELHQPVGPSWFSEQMGIMKPSHPDP-IIHTSDGRCSISFSVEEGINVLASLHGDD--GPITEETQRRYIFQLHREKQTELKVQLPHAGKFALKIYVMV 541

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BLAST of SWIM-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8C8H8|KY_MOUSE (Kyphoscoliosis peptidase OS=Mus musculus OX=10090 GN=Ky PE=1 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 2.287e-27
Identity = 81/231 (35.06%), Postives = 111/231 (48.05%), Query Frame = 1

Query: 3229 TTFTELVLYLTKDCSKDVEKVRAIFRWIT---TYDIKSV---NFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKI 3903
            +   ELV  L ++   D+E+VRAI+ WI     YD+++    +     P D    +LR  K        LF RMCR AG+ C  + GYSKG GY+ G +      F + W AVY+ G W  V+  WG             SG + + TS+  +L N     EFYFLT     I +HFPD K WQLL  P +L QF      KS F+N  +        +++T  GK T+ I
Sbjct:  166 SGLNELVSDLLQEAHSDLERVRAIWIWICHHIEYDVEAAQEKDRQAFKPTD----ILRTQKTNCDGYAGLFERMCRVAGVQCVTVPGYSKGFGYQTGQSFSGE--FDHAWNAVYLEGRWHLVDSTWG-------------SGLVDTTTSKFTFLYN-----EFYFLTHPALFIEDHFPDNKNWQLLKPPQSLRQFENSMYHKSEFYNKGMLSAHPETSMIRTVNGKATITI 372

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BLAST of SWIM-type domain-containing protein vs. TrEMBL
Match: A0A267DV76 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig019680g3 PE=4 SV=1)

HSP 1 Score: 541.576 bits (1394), Expect = 3.057e-161
Identity = 286/657 (43.53%), Postives = 415/657 (63.17%), Query Frame = 1

Query: 2977 SRTDLHNHLRPGLS------MSSLSD-----AYYQHTLDNDRMVYWRADIEELLXXXXXXXXXXXXTNLLKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRN-YAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGVLGSTPASQNLGII------ANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYA-----------------GVDDPDLPDTEPMECIYRLLIDCKRAQERIPPFPRQTSRWVGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDL--AVSSNGLWKGKVNTGQELENLSVYGKFGINEDDEFIKLLDYVLIAK 4836
            S + L N+L PG++        +L D     A  Q  L+  R V+W   + E  PP M+PPPKPMP  L K+  + P+    +D+ V+E++ ++  TF E V  L      DVEK RAIFR++T    + +++DP AP  TL+G LRA++ G++S +ELF RMC YAGIHC+ + GYSKGAGYRPGM +KDNRMFRN WTAVYV G WRFVN  WG R L  +  E     TL            ++  D FYFLT+  +HIFEH+PD+KRWQLL  PI L  FM LP++KSPFFNA +  K+  Y + L T+ G+V++KI + + VGVS +L+NR+D + +RG TL R++ G+++ V ASP+QPG ++L+++V  DW S ++ E+A SFQV C+E+N+DRL  GR+P+VG LG+TPA+Q  G+       A   +DP+ + + +  L++ +   PGL++  +M  Y R+G+++  CD YALLQ + + +S+Y +  P +G+Y  T+YA                  VDD +    E +EC+YRLLIDC+R   ++PP+P QTS + G  L +P+ +HL++   Y FR+ A  C +V+VV+N   W+DL    S NG+W  K+N G+EL  LSVYG+F  +ED +F KLLDY ++ +
Sbjct:  871 STSTLLNNLDPGVTNVYLGPEGTLRDGTAGYATLQRPLEPVRSVFWNPGVPETPPPAMRPPPKPMPPGLSKT--VPPDGWKSIDDHVMELLDVDCNTFAEQVNSLCGRYQSDVEKCRAIFRFLTARANQPLSYDPQAPVTTLIGCLRAVQMGEVSPHELFKRMCAYAGIHCEILHGYSKGAGYRPGMNVKDNRMFRNTWTAVYVEGCWRFVNVAWGGRRLRQQGGET----TL------------RLGCDNFYFLTEPDEHIFEHYPDEKRWQLLRSPIALSHFMKLPLLKSPFFNAGMRLKKGKYDDTLVTQNGRVSLKIGLTKFVGVSCQLQNRSDMSAMRGKTLVRLI-GEVLHVLASPAQPGTYFLNVFVTPDWTSNEH-ELAASFQVKCAENNFDRLALGRYPEVGFLGATPAAQKYGVSFLTSHGAKTPMDPYYVHNSKEVLRVPLVFSPGLKIAHQMKCYQRAGKSTEQCDDYALLQCRGKQQSEYWIACPADGYYFFTVYAAEIAAAAGADGDASTAESVDD-EAGGGEELECVYRLLIDCRRGMGKVPPYPNQTSLFSGCLLHDPMQKHLDVGRKYTFRLEAKHCRAVAVVLNGQTWIDLQQGRSGNGIWSKKLNVGEELGELSVYGQFDTDEDGKFNKLLDYDIVQR 1506

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BLAST of SWIM-type domain-containing protein vs. TrEMBL
Match: A0A267E954 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig031434g1 PE=4 SV=1)

HSP 1 Score: 543.888 bits (1400), Expect = 1.285e-157
Identity = 288/652 (44.17%), Postives = 412/652 (63.19%), Query Frame = 1

Query: 2968 MTMSRTDLHNHLRPGLS------MSSLSDAYYQHTL----DNDRMVYWRADIEELLXXXXXXXXXXXXTNLLKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKR-NYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGVLGSTPASQNLGII------ANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTEP------------MECIYRLLIDCKRAQERIPPFPRQTSRWVGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVNTGQELENLSVYGKFGINEDDEFIKLLDYVLIAK 4836
            +  S   L N+L PG++        +L +A   HT+    +  R V W     E+ PP M+PPPKPMP  L K+  + P+    VD+ V+E++ ++  TF E V  L      DVEK RAIFR++T   ++ + +DP AP  TL+G LR ++ G++S +ELF RMC +AGIHC+ + GYSKGAGYRPGM +KDNRMFRN WTAVYV G WRFVN  WG R L  R                S   E +++ D+FYFLT+ ++HI+EH+PD +RWQLL   +TL  FM LP++KSPFFNA L  K+  Y + L T+ G+V++KI + + VGVS +L+NR D + LRG TLAR++ G+ + V ASP+QPG ++L+I+V+ DW S ++ E+A SFQV C+E+N+DRL  GR+P+VG LG+TPA+Q LGI       A   +DP+V+   +  L+L +A  PGL+V  +M  Y RSG N+  CDSYALLQ + + +++Y L  P +G+Y  T+YAG       D+EP            ++C+YR+LIDC+R   ++P FP QTS + G  L EP+ +HL++   Y FR+ A    +V+VV+N   W+DL  S  G+W  K++ G+EL  LSVYG+   +E  +F KLLDY ++ +
Sbjct: 1687 LAASTATLLNNLEPGVTNVMLGPEGTLREAASMHTMLHPTEPARTVVWDPSQPEVPPPAMRPPPKPMPPGLSKT--VPPDGWKAVDDHVMEILDVDCNTFAEQVNSLCGRYQSDVEKCRAIFRFLTARLVQPLVYDPQAPPTTLIGCLRMVQAGEVSPHELFKRMCAHAGIHCEILHGYSKGAGYRPGMNLKDNRMFRNTWTAVYVEGCWRFVNVAWGGRRLAKR----------------SGATELRLKCDDFYFLTEPEEHIYEHWPDDRRWQLLRTSVTLSHFMRLPMLKSPFFNAGLRLKKGKYDDTLMTQNGRVSLKIGVTKFVGVSCQLQNRADMSSLRGKTLARLI-GEALHVLASPAQPGTYFLNIFVSPDWTSNEH-ELAASFQVKCAENNFDRLALGRYPEVGFLGATPAAQQLGISFLTSHGAKTPMDPYVVHTAKELLRLPVAAAPGLKVAHQMKCYQRSGVNTEQCDSYALLQCRGKQQAEYWLACPADGYYFFTVYAGE---AAKDSEPAGSAQDSEEGGDLDCVYRVLIDCRRGLGKVPAFPAQTSLFNGCYLHEPMHRHLDVGRKYNFRLEARHFKAVAVVLNGNTWLDLDSSRGGIWSKKLSVGEELGELSVYGQLQTDETGQFHKLLDYEIVQR 2315

[Close]

BLAST of SWIM-type domain-containing protein vs. TrEMBL
Match: A0A267G4V6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001514g4 PE=4 SV=1)

HSP 1 Score: 542.347 bits (1396), Expect = 5.219e-157
Identity = 287/652 (44.02%), Postives = 412/652 (63.19%), Query Frame = 1

Query: 2968 MTMSRTDLHNHLRPGLS------MSSLSDAYYQHTL----DNDRMVYWRADIEELLXXXXXXXXXXXXTNLLKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKR-NYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGVLGSTPASQNLGII------ANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTEP------------MECIYRLLIDCKRAQERIPPFPRQTSRWVGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVNTGQELENLSVYGKFGINEDDEFIKLLDYVLIAK 4836
            +  S   L N+L PG++        +L +A   HT+    +  R V W     E+ PP M+PPPKPMP  L K+  + P+    VD+ V+E++ ++  TF E V  L      DVEK RAIFR++T   ++ + +DP AP  TL+G LR ++ G++S +ELF RMC +AGIHC+ + GYSKGAGYRPGM +KDNRMFRN WTAVYV G WRFVN  WG R L  R                S   E +++ D+FYFLT+ ++HI+EH+PD +RWQLL   +TL  FM LP++KSPFFNA L  K+  Y + L T+ G+V++KI + + VGVS +L+NR D + LRG TLAR++ G+++ V ASP+QPG ++L+I+V+ DW S ++ E+A SFQV C+E+N+DRL  GR+P+VG LG+TPA+Q LGI       A   +DP+V+   +  L+L +A  PGL+V  +M  Y RSG N+  CD YALLQ + + +++Y L  P +G+Y  T+YAG       D+EP            ++C+YR+LIDC+R   ++P FP QTS + G  L EP+ +HL++   Y FR+ A    +V+VV+N   W+DL  S  G+W  K++ G+EL  LSVYG+   +E  +F KLLDY ++ +
Sbjct: 1696 LAASTATLLNNLEPGVTNVMLGPEGTLREAASMHTMLHPTEPARTVVWDPSQPEVPPPAMRPPPKPMPPGLSKT--VPPDGWKAVDDHVMEILDIDCNTFAEQVNSLCGRYQSDVEKCRAIFRFLTARLVQPLVYDPQAPPTTLIGCLRMVQAGEVSPHELFKRMCAHAGIHCEILHGYSKGAGYRPGMNLKDNRMFRNTWTAVYVEGCWRFVNVAWGGRRLAKR----------------SGATELRLKCDDFYFLTEPEEHIYEHWPDDRRWQLLRTSVTLSHFMRLPMLKSPFFNAGLRLKKGKYDDTLMTQNGRVSLKIGVTKFVGVSCQLQNRADMSSLRGKTLARLI-GEVLHVLASPAQPGTYFLNIFVSPDWTSNEH-ELAASFQVKCAENNFDRLALGRYPEVGFLGATPAAQQLGISFLTSHGAKTPMDPYVVHTAKELLRLPVAAAPGLKVAHQMKCYQRSGVNTEQCDPYALLQCRGKQQAEYWLACPADGYYFFTVYAGE---AAKDSEPAGSAQDSEEGGDLDCVYRVLIDCRRGLGKVPAFPAQTSLFNGCYLHEPMQRHLDVGRKYNFRLEARHFKAVAVVLNGNTWLDLDSSRGGIWSKKLSVGEELGELSVYGQLQTDETGQFHKLLDYEIVQR 2324

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BLAST of SWIM-type domain-containing protein vs. TrEMBL
Match: A0A267EBZ4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001514g2 PE=4 SV=1)

HSP 1 Score: 542.732 bits (1397), Expect = 5.366e-157
Identity = 287/652 (44.02%), Postives = 412/652 (63.19%), Query Frame = 1

Query: 2968 MTMSRTDLHNHLRPGLS------MSSLSDAYYQHTL----DNDRMVYWRADIEELLXXXXXXXXXXXXTNLLKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKR-NYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGVLGSTPASQNLGII------ANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTEP------------MECIYRLLIDCKRAQERIPPFPRQTSRWVGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVNTGQELENLSVYGKFGINEDDEFIKLLDYVLIAK 4836
            +  S   L N+L PG++        +L +A   HT+    +  R V W     E+ PP M+PPPKPMP  L K+  + P+    VD+ V+E++ ++  TF E V  L      DVEK RAIFR++T   ++ + +DP AP  TL+G LR ++ G++S +ELF RMC +AGIHC+ + GYSKGAGYRPGM +KDNRMFRN WTAVYV G WRFVN  WG R L  R                S   E +++ D+FYFLT+ ++HI+EH+PD +RWQLL   +TL  FM LP++KSPFFNA L  K+  Y + L T+ G+V++KI + + VGVS +L+NR D + LRG TLAR++ G+++ V ASP+QPG ++L+I+V+ DW S ++ E+A SFQV C+E+N+DRL  GR+P+VG LG+TPA+Q LGI       A   +DP+V+   +  L+L +A  PGL+V  +M  Y RSG N+  CD YALLQ + + +++Y L  P +G+Y  T+YAG       D+EP            ++C+YR+LIDC+R   ++P FP QTS + G  L EP+ +HL++   Y FR+ A    +V+VV+N   W+DL  S  G+W  K++ G+EL  LSVYG+   +E  +F KLLDY ++ +
Sbjct: 1728 LAASTATLLNNLEPGVTNVMLGPEGTLREAASMHTMLHPTEPARTVVWDPSQPEVPPPAMRPPPKPMPPGLSKT--VPPDGWKAVDDHVMEILDIDCNTFAEQVNSLCGRYQSDVEKCRAIFRFLTARLVQPLVYDPQAPPTTLIGCLRMVQAGEVSPHELFKRMCAHAGIHCEILHGYSKGAGYRPGMNLKDNRMFRNTWTAVYVEGCWRFVNVAWGGRRLAKR----------------SGATELRLKCDDFYFLTEPEEHIYEHWPDDRRWQLLRTSVTLSHFMRLPMLKSPFFNAGLRLKKGKYDDTLMTQNGRVSLKIGVTKFVGVSCQLQNRADMSSLRGKTLARLI-GEVLHVLASPAQPGTYFLNIFVSPDWTSNEH-ELAASFQVKCAENNFDRLALGRYPEVGFLGATPAAQQLGISFLTSHGAKTPMDPYVVHTAKELLRLPVAAAPGLKVAHQMKCYQRSGVNTEQCDPYALLQCRGKQQAEYWLACPADGYYFFTVYAGE---AAKDSEPAGSAQDSEEGGDLDCVYRVLIDCRRGLGKVPAFPAQTSLFNGCYLHEPMQRHLDVGRKYNFRLEARHFKAVAVVLNGNTWLDLDSSRGGIWSKKLSVGEELGELSVYGQLQTDETGQFHKLLDYEIVQR 2356

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BLAST of SWIM-type domain-containing protein vs. TrEMBL
Match: A0A430QMV6 (Uncharacterized protein OS=Schistosoma bovis OX=6184 GN=DC041_0000731 PE=4 SV=1)

HSP 1 Score: 531.561 bits (1368), Expect = 2.620e-156
Identity = 274/581 (47.16%), Postives = 377/581 (64.89%), Query Frame = 1

Query: 3157 SAIISPESLIHVDNM-VIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARIL--DGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRL-VTGRFPDVGVLGSTPASQNLGIIANPGVD-----PFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQ--------------YQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTEPMECIYRLLIDCK--RAQERIPPFPRQTSRWVGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSS---------------NGLWKGKVNTGQELENLSVYGKF 4779
            + I+ P+  I V +M  IEV      TF+EL+  LT     +VE +R+++RW T  D +  ++DP AP D+L+G+LR +K  Q+S NELF+ +CRYAG+ CQ+I+GYSKGAGYRPGM IKDN++FRN W AVY+   WRFVNCNWGARYL+   + LP       R+S S+        DEFYFLTD +QH+FE+ PD K WQLL +P+++D+F  LP++KSPFFNANL  K+NY++ L TK G+V+VKI M + VG+S  LEN  D +IL GL L  IL      + + A+PSQPGK+YL++YV+ DW+ ED  E+ACSFQ+HCSE+NY RL VTGR P+VG LG TPAS+  G++  P  D     P+++ ++   LK+  AI PGL++  ++ S+DR G   A CDSYALLQ              ++SQ  + Y++R P++ FY LTIYA  ++  + D   ++C+YR+LID +  R+ E I  +PRQT  WV  RL+EP  QHL +N  Y+F + A QC SV+VVIN ++W  L  SS               +G W GKV TG+ L  LSV+G+ 
Sbjct: 1044 TTILPPDDRIRVIDMHAIEVTNRVHMTFSELISDLTTGIDNEVEVIRSLYRWTTGKDTRYEDYDPEAPCDSLIGMLRQMKYNQLSRNELFYELCRYAGLQCQYITGYSKGAGYRPGMPIKDNQLFRNTWLAVYICDGWRFVNCNWGARYLS---ENLPD-----GRSSSSE-------CDEFYFLTDPEQHVFENLPDLKVWQLLRKPLSMDRFCHLPLLKSPFFNANLFLKKNYSDCLVTKNGQVSVKIKMSRFVGISCSLENCADHSILLGLCLVEILLRPPGTVRIEAAPSQPGKYYLNVYVSPDWRREDIRELACSFQIHCSEYNYSRLVVTGRLPEVGFLGRTPASEVHGVLMVPEGDASDGRPYIIHNDPRPLKIPFAIAPGLKLCHQLKSFDRPGHQMADCDSYALLQMKPNHHSSITHSKPFKSQANAYYNVRLPVQAFYYLTIYAFNENDIVKDH--LDCVYRILIDARNCRSSELIQAYPRQTFWWVQCRLIEPKYQHLFINRNYKFCLDAPQCDSVAVVINGSEWHFLTPSSPISPSKLHSPSGSNHHGRWSGKVYTGKCLGQLSVFGRI 1607

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BLAST of SWIM-type domain-containing protein vs. Ensembl Cavefish
Match: ky (uncharacterized LOC103044048 [Source:NCBI gene;Acc:103044048])

HSP 1 Score: 119.013 bits (297), Expect = 1.708e-26
Identity = 87/332 (26.20%), Postives = 152/332 (45.78%), Query Frame = 1

Query: 3190 VDNMVIEV--MLLEPTTFT--ELVLYLTKDCSKDVEKVRAIFRWIT---TYDIKS-VNFDPA-APNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKI---RSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTAS---------PSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHC 4122
            VD + I     L E   F+   +   +T+    ++EK+RAI+ W+     YD++  +   P     + ++   R + C   S+  +   MCR  G+ C+ +SGYSKG G+ PG  +  +R   + W  V+V   W  ++  WGA             GT+         +E K    R D+FYFLTD  + I  HFPD++ WQLL  PI+L++F   P+  S F+   L+ ++     + T+ G+ TV +   + +  + +L  R    +  G+   R +D    +++ +         P  PG + L ++   +  S   +   CS ++ C
Sbjct:  195 VDTLAISAGRELKEQGVFSAQSIARAITQGAINELEKLRAIWVWLCHNIEYDLEGYLGLSPKLCTPEEVIKQGRGV-CSGFSS--ICLEMCREVGVQCEEVSGYSKGIGHSPGRKLAQDRS-DHSWNVVWVKDRWGLLDACWGA-------------GTV--------NMETKTFVKRFDDFYFLTDPSEFINSHFPDEQHWQLLDTPISLEKFELGPLKTSAFYTLGLTLQQPTQYKITTEDGEATVSVTSSRPLTFAYELRQR---DVQTGVPGQREVDSSCGLLSVTRQGMSLRLLPPDPGDYELKLFARAEGDS-GALRWVCSLELEC 497

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Query: 3190 VDNMVIEV--MLLEPTTFT--ELVLYLTKDCSKDVEKVRAIFRWIT---TYDIKS-VNFDPA-APNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKI---RSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTAS---------PSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHC 4122
            VD + I     L E   F+   +   +T+    ++EK+RAI+ W+     YD++  +   P     + ++   R + C   S+  +   MCR  G+ C+ +SGYSKG G+ PG  +  +R   + W  V+V   W  ++  WGA             GT+         +E K    R D+FYFLTD  + I  HFPD++ WQLL  PI+L++F   P+  S F+   L+ ++     + T+ G+ TV +   + +  + +L  R    +  G+   R +D    +++ +         P  PG + L ++   +  S   +   CS ++ C
Sbjct:  195 VDTLAISAGRELKEQGVFSAQSIARAITQGAINELEKLRAIWVWLCHNIEYDLEGYLGLSPKLCTPEEVIKQGRGV-CSGFSS--ICLEMCREVGVQCEEVSGYSKGIGHSPGRKLAQDRS-DHSWNVVWVKDRWGLLDACWGA-------------GTV--------NMETKTFVKRFDDFYFLTDPSEFINSHFPDEQHWQLLDTPISLEKFELGPLKTSAFYTLGLTLQQPTQYKITTEDGEATVSVTSSRPLTFAYELRQR---DVQTGVPGQREVDSSCGLLSVTRQGMSLRLLPPDPGDYELKLFARAEGDS-GALRWVCSLELEC 497

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BLAST of SWIM-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000032424.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000151.1:316716:330052:1 gene:ENSAMXG00000039459.1 transcript:ENSAMXT00000032424.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.99 bits (258), Expect = 5.393e-22
Identity = 73/297 (24.58%), Postives = 132/297 (44.44%), Query Frame = 1

Query: 3271 SKDVEKVRAIFRWIT---TYDIKS---VNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLEN-----RTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSE 4128
            + D+E++RA++ W+     YD++    V     +P+D    V+R  K        +  ++C   GI C+ ++GY KG GY PG   +      + W AV + G W  ++  WGA                      SQ + NK   +EFYFLTD ++ I +H+P +++WQLL RP+ L +F       + F+   L+        L T+ G+ T+ + + +    +  +       +T+ +  RGL        ++ V+   P   G F + ++      +     + CSF + C++
Sbjct:   59 TNDLERLRAVWIWLCDNIEYDVEGFLGVTKKLYSPDD----VIRTGKAVCSGYAGVCLQLCNVVGIECREVNGYGKGVGYEPGQKCQGTN---HAWNAVNLEGHWHLLDSCWGA-----------------GNCDMSQRVFNKCY-NEFYFLTDPEEFINDHYPAEEKWQLLERPVNLKEFEKKVTKSAQFYRLGLTLIHPKQCSLDTENGEATISMGLSEPANFTYTISQCNGSKKTELSKSRGLLTITKSSMKLRVI---PPTAGSFEVELFARAAGVTGSYSHL-CSFLLKCAK 326

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BLAST of SWIM-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000040397.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000151.1:312137:330052:1 gene:ENSAMXG00000039459.1 transcript:ENSAMXT00000040397.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.99 bits (258), Expect = 7.038e-22
Identity = 73/298 (24.50%), Postives = 135/298 (45.30%), Query Frame = 1

Query: 3271 SKDVEKVRAIFRWIT---TYDIKS---VNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTAS------PSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSE 4128
            + D+E++RA++ W+     YD++    V     +P+D    V+R  K        +  ++C   GI C+ ++GY KG GY PG   +      + W AV + G W  ++  WGA                      SQ + NK   +EFYFLTD ++ I +H+P +++WQLL RP+ L +F       + F+   L+        L T+ G+ T+ + + +    +  + ++ +G+    L+ +R   G + +  +S      P   G F + ++      +     + CSF + C++
Sbjct:  220 TNDLERLRAVWIWLCDNIEYDVEGFLGVTKKLYSPDD----VIRTGKAVCSGYAGVCLQLCNVVGIECREVNGYGKGVGYEPGQKCQGTN---HAWNAVNLEGHWHLLDSCWGA-----------------GNCDMSQRVFNKCY-NEFYFLTDPEEFINDHYPAEEKWQLLERPVNLKEFEKKVTKSAQFYRLGLTLIHPKQCSLDTENGEATISMGLSEPANFTYTI-SQCNGSKKTELSKSR---GLLTITKSSMKLRVIPPTAGSFEVELFARAAGVTGSYSHL-CSFLLKCAK 487

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BLAST of SWIM-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009155.1 (pep scaffold:Pmarinus_7.0:GL483885:156116:165500:-1 gene:ENSPMAG00000008280.1 transcript:ENSPMAT00000009155.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.5666 bits (192), Expect = 1.058e-16
Identity = 56/202 (27.72%), Postives = 91/202 (45.05%), Query Frame = 1

Query: 3241 ELVLYLTKDCSKDVEKVRAIFRWIT---TYDIKSVNFDPAAPNDTLVGVL--RAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFN 3831
            ++V  +T+D   ++EK+R+I+ W+     YD+K   F     N     VL  R   C   +   L   MCR+ G+ C+ + GY K  G+ P   I+D     + W AV + G W  ++  WGA  +++  Q                      R +EFYFL D K+ +  H+P   +WQL+   ++ + F    +    FFN
Sbjct:    1 KIVEMITQDTQTELEKLRSIWIWVCHNIEYDVKYW-FGKDKSNYKKEDVLSSRTAICAGYAG--LVNEMCRHVGVECEEVVGYGKTLGHVP-FQIEDPN---HAWNAVRIGGRWYLLDACWGAGAVSNETQSFNR------------------RYNEFYFLADPKKFVESHWPKISKWQLMEHLVSREDFEYRVLKDFRFFN 177

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BLAST of SWIM-type domain-containing protein vs. Ensembl Nematostella
Match: EDO40037 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8B7])

HSP 1 Score: 66.6254 bits (161), Expect = 8.285e-11
Identity = 66/307 (21.50%), Postives = 127/307 (41.37%), Query Frame = 1

Query: 3295 AIFRWIT---TYDIKSVNFDPAAPNDTL---VGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTI----LRGLTLARILDGQMIV---VTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGV 4176
            A++RWIT   ++D +   F  A   +     V V R+      +N  LF  +C  A I  + + G++KG GY  G  I+ ++ F + W  +     W   +  WG+ +L            +  R   + Y           F+   +  I +HFP   +WQLL   I+ ++F  L +     F++ L  + +     Q +   + + +  P+   +   L++ +  TI    +  +T  ++ +   ++   VT    +PG++ + I +     +E  +     ++V CS        TG FP +G 
Sbjct:  217 ALYRWITLNVSFDSEGY-FGRAEKKECRAESVLVTRSAVSQGFAN--LFQALCMEADIQARSVDGFAKGYGYCAGDEIQGSK-FAHTWNILRTRVGWTICDVTWGSGFL--------GDDLMFHRQPNAHY-----------FMVTPELAISDHFPLDTKWQLLDAVISKEEFENLIVPSPAIFSSGLRLESHKNCFYQEESDSIVITLRAPKRNMIRGVLKDSSGQTIGPRNMIDVTSGKLKEADFLIPVKVTTHFPEPGEYRVQICL---VSAEGQLVPGVEYRVRCSRGVGQN--TGGFPHLGT 495

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BLAST of SWIM-type domain-containing protein vs. Ensembl Nematostella
Match: EDO32609 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUI9])

HSP 1 Score: 64.3142 bits (155), Expect = 4.251e-10
Identity = 69/321 (21.50%), Postives = 121/321 (37.69%), Query Frame = 1

Query: 3187 HVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWIT---TYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQF--MALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARI-LDG-QMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSE 4128
             +D  V         +  +L  YLT+  S D EK  AI+RW+T    YD+          + +   VL +          L+  +   AG+    +SGY+KG G++ G   +      + W  + V   W   +  WGA ++            L ++   +           + FL    + IF+H P++++WQ L   I    F   A P  +       L   ++YA   +T    + +    P    + +     + G  L G    R+   G   I + A     G + + +YV    K E++     S++V  S+
Sbjct:  197 EIDKHVQNTPASATASINQLSDYLTECFSTDREKAFAIYRWLTFNVAYDVDGFFGRSEKKSTSAEDVLSSRTSVCAGYASLYTALGEAAGLEIHNVSGYAKGYGHKLGQRFEG---VNHAWNVLKVDNTWYVSDATWGAGFV--------GDDMLFTKNPNT-----------YRFLQVPDEAIFDHLPEEEKWQFLDPTIDKASFERSAKPSCEMLEMGIELESHKDYA--YETPTDTIDMTFYCPGRKMLLMGKVKTSSGQALEGRERVRLRFKGLHQIEMRAQFPNAGTYKVEVYV---VKGENSWNHGVSYEVTASQ 490

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BLAST of SWIM-type domain-containing protein vs. Ensembl Medaka
Match: ky (kyphoscoliosis peptidase [Source:NCBI gene;Acc:101165522])

HSP 1 Score: 112.079 bits (279), Expect = 1.945e-24
Identity = 92/378 (24.34%), Postives = 152/378 (40.21%), Query Frame = 1

Query: 3244 LVLYLTKDCSKDVEKVRAIFRWIT---TYDIKSV--NFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTAS---------PSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHC---------SEHNYDRLVTGRFPDVGVLGSTPASQNLGII-ANPGVDPFVLWDERSTLKLNIAIRPGLRVG 4305
            +V  +T++   +++++RAI+ W+     YD+       +  +  + ++   R + C   S + L   MCR  GI CQ + G+SKG GYR G +++      ++W AV + G W  ++  WGA  +   H+                      R D+FYFLTD ++ I  HFP++++WQLL  PI L+ F       S FF   L     +   + T  G+  V I        + ++    D      L           ++T S         P   G +   ++   + K+   +   CSF V C          E+ Y  L  G  P    LG    SQ+  +   + GV   VL   R  + L   + P +   
Sbjct:  200 IVHSITRESRNELDRLRAIWVWLCHNIEYDVSGYLGRSEKLSSLEEVIAAGRGVCC---SYSSLCLEMCREVGIECQEVPGHSKGVGYRQGQSLRHVNS-DHLWNAVLLGGQWFLLDACWGAGRVDMEHESFVR------------------RFDDFYFLTDPEEFIESHFPEEEKWQLLDTPIILEDFEKRVFKTSAFFTLGLRLINPHHFHIVTDDGEANVSIGFSSPTTFTYEITQHRDLLHCGALEQKESSSSSFGILTVSHRSMNLQLLPPATGSYDCKVFARHE-KASTPLVWVCSFTVECLAPRAMEVIPENPY--LSWGMQPVAASLGVADCSQSREVAEVDKGVFDLVLKTSRPLMVLCELVHPQMEAA 552

HSP 2 Score: 56.225 bits (134), Expect = 3.434e-7
Identity = 84/342 (24.56%), Postives = 136/342 (39.77%), Query Frame = 1

Query: 3832 ANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNY--DRL-------VTGRFPDVGVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTE--PMECIYRLLIDCKRAQERIPPFPRQTSRW-VGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVNTGQELENLSVYGKFGINEDDEFIKLLDY 4821
            A+ S  R  AEV    KG   + +   + + V  +L +      L    LA  +   +++       PG + LS++V +  KSE   + A +F +HC    +  D L         G        G +  S N  +++       + +  +  L+L+             +S D S   + P   + L  Y +  +    +  P  G Y L +YA V     P  E  PM C + L   C       PPFP   S W  G  L EP    L+  +   FR+       VSVV  +T+  DL ++ + +W+G+V TG  L+ L +   F   E D+   L+ +
Sbjct:  512 ADCSQSREVAEV---DKGVFDLVLKTSRPLMVLCELVHPQMEAALAKRCLATQIQPDILLCHVLCPFPGFYRLSVFVRDYEKSELKFQNAANFLLHCKGKVFHVDELFPPNLGSACGPGTRTAQAGLSKFSHNASVVSTQQGKCNITFHNQRDLELHCT-----------LSRDESKAPAVPLSRHLLCTY-TDTKVTVSISLPEVGVYRLGLYARVG----PGGEFSPM-CDFVLRNSCALPG---PPFPCLYSAWRKGCVLFEPRAGLLDPLSRVHFRVRVPGALRVSVV-GETR-TDLTLNKSRVWEGEVFTGDALQQLKLAACF--RESDDMAVLMTF 826

[Close]

BLAST of SWIM-type domain-containing protein vs. Ensembl Medaka
Match: ky (kyphoscoliosis peptidase [Source:NCBI gene;Acc:101165522])

HSP 1 Score: 110.153 bits (274), Expect = 7.697e-24
Identity = 76/307 (24.76%), Postives = 129/307 (42.02%), Query Frame = 1

Query: 3244 LVLYLTKDCSKDVEKVRAIFRWIT---TYDIKSV--NFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTAS---------PSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHC 4122
            +V  +T++   +++++RAI+ W+     YD+       +  +  + ++   R + C   S + L   MCR  GI CQ + G+SKG GYR G +++      ++W AV + G W  ++  WGA  +   H+                      R D+FYFLTD ++ I  HFP++++WQLL  PI L+ F       S FF   L     +   + T  G+  V I        + ++    D      L           ++T S         P   G +   ++   + K+   +   CSF V C
Sbjct:  200 IVHSITRESRNELDRLRAIWVWLCHNIEYDVSGYLGRSEKLSSLEEVIAAGRGVCC---SYSSLCLEMCREVGIECQEVPGHSKGVGYRQGQSLRHVNS-DHLWNAVLLGGQWFLLDACWGAGRVDMEHESFVR------------------RFDDFYFLTDPEEFIESHFPEEEKWQLLDTPIILEDFEKRVFKTSAFFTLGLRLINPHHFHIVTDDGEANVSIGFSSPTTFTYEITQHRDLLHCGALEQKESSSSSFGILTVSHRSMNLQLLPPATGSYDCKVFARHE-KASTPLVWVCSFTVEC 483

HSP 2 Score: 55.0694 bits (131), Expect = 6.805e-7
Identity = 71/275 (25.82%), Postives = 112/275 (40.73%), Query Frame = 1

Query: 4033 PGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNY--DRL-------VTGRFPDVGVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTE--PMECIYRLLIDCKRAQERIPPFPRQTSRW-VGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVNTGQELENLSVYGKFGINEDDEFIKLLDY 4821
            PG + LS++V +  KSE   + A +F +HC    +  D L         G        G +  S N  +++       + +  +  L+L+             +S D S   + P   + L  Y +  +    +  P  G Y L +YA V     P  E  PM C + L   C       PPFP   S W  G  L EP    L+  +   FR+       VSVV  +T+  DL ++ + +W+G+V TG  L+ L +   F   E D+   L+ +
Sbjct:  550 PGFYRLSVFVRDYEKSELKFQNAANFLLHCKGKVFHVDELFPPNLGSACGPGTRTAQAGLSKFSHNASVVSTQQGKCNITFHNQRDLELHCT-----------LSRDESKAPAVPLSRHLLCTY-TDTKVTVSISLPEVGVYRLGLYARVG----PGGEFSPM-CDFVLRNSCALPG---PPFPCLYSAWRKGCVLFEPRAGLLDPLSRVHFRVRVPGALRVSVV-GETR-TDLTLNKSRVWEGEVFTGDALQQLKLAACF--RESDDMAVLMTF 800

[Close]

BLAST of SWIM-type domain-containing protein vs. Planmine SMEST
Match: SMESG000060198.1 (SMESG000060198.1)

HSP 1 Score: 2790.37 bits (7232), Expect = 0.000e+0
Identity = 1575/1576 (99.94%), Postives = 1575/1576 (99.94%), Query Frame = 1

Query:  118 MSFNNSHHIENVKLFTNRFPRKSQEKIYHXXXXXXXXXXXXXXXXXXXXXXXXXXXXFVILDDYTTLKTELKNNQISPSILKRLXXXXXXXXXXXXHPLLSTKTKSLPIIFXXXXXXXXXXXXXXXXXXNEXXXXXXXXXXXXVLANEMNSKNSNEILILNQSNSSEITNNSYQNSVSQLQHNQPIRIKKTNSIDSSNKISPALLIVDDNSNNDFKMCDSLNGNQTTMCNNNATTLHTHNSSSIADLDMAHQFIGVPEWTKINKSSNSLSQSTELIFNKRTPRFPVKNNSNTVENSENKHLLIPDQFECENTMKNYXXXXXXXXXXXXXXEKLENNNLRISNKIPPNETPNETILDHQKKPPVGRKPKNEKEHTEPTTDLDDLIEGHHRXXXXXXXXXXXXXXXXXGGNEPAKTESYFKKEMLKNYTKTDLIIMPIKTQQNSASNNRLYEKKQDQGKVENTKTKPSETIGLLSYQKDSPSKRSQELVGSVVKMDKTINRVTNNIERIDNAIDKLSQFNKAYMSNLETMSDSELSIDFETHSIGAQTDLSNPNYHEKSSENSNKVQEXXXXXXXXXXXXITPXXXXXXXXXXXXXXXXXXXXXXXVALKPSPVHQIIDKPIIKFRXXXXXXXXXXXXXILDSKTDGNKFFRTSNLAHTESDVSSLPESSVCENPETRDLVGKVKYFQRQIIKSSGLYKKPPNIEPPKKLVVEEPHLKVQSSQRPIPKPRNSIDYALRRMXXXXXXXXXFDFNGKTLSNSNNHTQISPSPGNSDSGSIISLGSNHLERKFQKGAGASARYNTKSKPNDKWGTVGSRRSQKSKPEEECASLSGRPMPNKNQMKIYMXXXXXXXXXXXXXXXXPDEKSKYGSLAALNKNYGLQDINSLCDIIRQNLNLNNHDKIRNIFNALIIENEHDKIDVIIDNFXXXXXXXXXXXXPDNHYTSKDAESIFDMTMSRTDLHNHLRPGLSMSSLSDAYYQHTLDNDRMVYWRADIEELLXXXXXXXXXXXXTNLLKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTEPMECIYRLLIDCKRAQERIPPFPRQTSRWVGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVNTGQELENLSVYGKFGINEDDEFIKLLDYVLIAKSNK 4845
            MSFNNSHHIENVKLFTNRFPRKSQEKIYHEEIEDFDSSESSESSYDCTSDGSSSSDEFVILDDYTTLKTELKNNQISPSILKRLSKNQKSNKKNVNHPLLSTKTKSLPIIFERSDESSVSSQSTLELSENESTLSDCSTSSSSVLANEMNSKNSNEILILNQSNSSEITNNSYQNSVSQLQHNQPIRIKKTNSIDSSNKISPALLIVDDNSNNDFKMCDSLNGNQTTMCNNNATTLHTHNSSSIADLDMAHQFIGVPEWTKINKSSNSLSQSTELIFNKRTPRFPVKNNSNTVENSENKHLLIPDQFECENTMKNYQYQQKKPPVSVKPVEKLENNNLRISNKIPPNETPNETILDHQKKPPVGRKPKNEKEHTEPTTDLDDLIEGHHRNSNESLELSSSSASHSSGGNEPAKTESYFKKEMLKNYTKTDLIIMPIKTQQNSASNNRLYEKKQDQGKVENTKTKPSETIGLLSYQKDSPSKRSQELVGSVVKMDKTINRVTNNIERIDNAIDKLSQFNKAYMSNLETMSDSELSIDFETHSIGAQTDLSNPNYHEKSSENSNKVQENSNNKYPKNSSKITPENESSSSDESSTEKETSSESENSVALKPSPVHQIIDKPIIKFRSSSPGYKSSPSKPILDSKTDGNKFFRTSNLAHTESDVSSLPESSVCENPETRDLVGKVKYFQRQIIKSSGLYKKPPNIEPPKKLVVEEPHLKVQSSQRPIPKPRNSIDYALRRMSNSSSESSNFDFNGKTLSNSNNHTQISPSPGNSDSGSIISLGSNHLERKFQKGAGASARYNTKSKPNDKWGTVGSRRSQKSKPEEECASLSGRPMPNKNQMKIYMNQSRSYNNLNSLNSKNPDEKSKYGSLAALNKNYGLQDINSLCDIIRQNLNLNNHDKIRNIFNALIIENEHDKIDVIIDNFEENERNILLELIPDNHYTSKDAESIFDMTMSRTDLHNHLRPGLSMSSLSDAYYQHTLDNDRMVYWRADIEELLPPPMKPPPKPMPTNLLKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSR QELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTEPMECIYRLLIDCKRAQERIPPFPRQTSRWVGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVNTGQELENLSVYGKFGINEDDEFIKLLDYVLIAKSNK
Sbjct:    1 MSFNNSHHIENVKLFTNRFPRKSQEKIYHEEIEDFDSSESSESSYDCTSDGSSSSDEFVILDDYTTLKTELKNNQISPSILKRLSKNQKSNKKNVNHPLLSTKTKSLPIIFERSDESSVSSQSTLELSENESTLSDCSTSSSSVLANEMNSKNSNEILILNQSNSSEITNNSYQNSVSQLQHNQPIRIKKTNSIDSSNKISPALLIVDDNSNNDFKMCDSLNGNQTTMCNNNATTLHTHNSSSIADLDMAHQFIGVPEWTKINKSSNSLSQSTELIFNKRTPRFPVKNNSNTVENSENKHLLIPDQFECENTMKNYQYQQKKPPVSVKPVEKLENNNLRISNKIPPNETPNETILDHQKKPPVGRKPKNEKEHTEPTTDLDDLIEGHHRNSNESLELSSSSASHSSGGNEPAKTESYFKKEMLKNYTKTDLIIMPIKTQQNSASNNRLYEKKQDQGKVENTKTKPSETIGLLSYQKDSPSKRSQELVGSVVKMDKTINRVTNNIERIDNAIDKLSQFNKAYMSNLETMSDSELSIDFETHSIGAQTDLSNPNYHEKSSENSNKVQENSNNKYPKNSSKITPENESSSSDESSTEKETSSESENSVALKPSPVHQIIDKPIIKFRSSSPGYKSSPSKPILDSKTDGNKFFRTSNLAHTESDVSSLPESSVCENPETRDLVGKVKYFQRQIIKSSGLYKKPPNIEPPKKLVVEEPHLKVQSSQRPIPKPRNSIDYALRRMSNSSSESSNFDFNGKTLSNSNNHTQISPSPGNSDSGSIISLGSNHLERKFQKGAGASARYNTKSKPNDKWGTVGSRRSQKSKPEEECASLSGRPMPNKNQMKIYMNQSRSYNNLNSLNSKNPDEKSKYGSLAALNKNYGLQDINSLCDIIRQNLNLNNHDKIRNIFNALIIENEHDKIDVIIDNFEENERNILLELIPDNHYTSKDAESIFDMTMSRTDLHNHLRPGLSMSSLSDAYYQHTLDNDRMVYWRADIEELLPPPMKPPPKPMPTNLLKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRLQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDVGVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTEPMECIYRLLIDCKRAQERIPPFPRQTSRWVGFRLVEPLCQHLELNTPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVNTGQELENLSVYGKFGINEDDEFIKLLDYVLIAKSNK 1576

[Close]

BLAST of SWIM-type domain-containing protein vs. Planmine SMEST
Match: SMESG000061907.1 (SMESG000061907.1)

HSP 1 Score: 160.999 bits (406), Expect = 3.137e-39
Identity = 99/327 (30.28%), Postives = 162/327 (49.54%), Query Frame = 1

Query: 3172 PESLIHVDNMVIEVMLLEPTTFTELVLYLT-KDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAVGVSVKLE-----NRTDGTILRGLTLARILDGQMIVVTASPSQPGKFYLSIYV------NEDWKSEDNMEMACSFQV 4116
            P     VD   I V      TF +L+  L  +    D+EK R IFRW+T  D+  ++F  + PN     VL ++K  + S    F  MC YAG+ C  ISG++KG  Y+PG   K +  F + W  +++  +W+ ++ +W  RYLTS        G     +   QY       D+FYF+ + +Q ++ HFP+K  WQLL +P+TL+QF  LP+ KS FF   + F+  +  V+ +K G + + +   +    + KL+     ++ +G  LR   L   ++ Q+      P+  G FYL+I+       N+    E+    AC +++
Sbjct:   35 PYVFEKVDGHAIRVSQNSYPTFKDLLWDLAFRYQLSDLEKARVIFRWMTACDMNKLDFANSHPNGP-EEVLLSLKNLKGSYANAFEFMCSYAGLCCLTISGFAKGVDYKPGDVFKKDE-FNHTWNVIHLQNSWQLIDAHWATRYLTS--------GKNTQDSIVYQY-------DDFYFIMEPQQAVYSHFPEKTEWQLLEKPLTLNQFENLPLTKSQFFKCGMDFRSQHHGVVHSKDGYLKMNLGFWKPDSFTYKLQTDENKDQFEGVSLRYYVLQETVNNQINFFFRFPTA-GVFYLTIFAQELNEHNQPVTQENTFRAACEYKI 343

HSP 2 Score: 157.532 bits (397), Expect = 4.580e-38
Identity = 87/259 (33.59%), Postives = 133/259 (51.35%), Query Frame = 1

Query: 3166 ISPES----LIHVDNMVIEVMLLEPTTFTELV--LYLTKDCSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLEN-KIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMPQAV 3921
            ISPE        VD   ++V   +   F +L+  L   ++ + ++EKVR IF W+ T D+  +NFD     D+   +L  I+ G+ +  ++F  +CRYAG+HC+ I GY+KGA Y PGM  +  R   + W AV + G WR ++C+W AR L  +  +                 EN +   D FYFL +  Q I+ HFP    WQLL   I +++F +L  VKS FF  NL    +   V+QT   +  ++I  P+ +
Sbjct: 1135 ISPEETSKIFQKVDEHAMQVSSQQQDNFNQLIWQLIYARNITDELEKVRVIFLWLCTKDLHKMNFD-NIKQDSPEEILMGIRTGKSTYAQIFLTLCRYAGLHCKLIVGYAKGADYVPGMKFQ-GRQGEHSWNAVLIEGVWRLIDCHWAARRLIGKEHKP----------------ENVRYELDMFYFLANPSQLIYTHFPHDNDWQLLHHSINIEEFESLAPVKSMFFKYNLDLVTHKNAVIQTNAPEFELRIAFPKGI 1375

HSP 3 Score: 68.5514 bits (166), Expect = 4.540e-11
Identity = 73/299 (24.41%), Postives = 129/299 (43.14%), Query Frame = 1

Query: 3979 LARILDGQMIVVTASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPDV--GVLGS-TPASQNLGIIANPGVDPFVLWDERST-LKLNIAIRPGLRVGQKMMSYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPDLPDTEPMEC---IYRLLIDCKRAQERIPPFPRQTSRWV-GFRLVEPLCQHLELN-TPYR--FRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVN-----TGQELENLSVYGKFGINEDDEFIKLLDYVL 4827
            L R++     ++       G++ L +Y N+  K+ ++      + +  S  +   +V+G  P +  G LG   P   + G+      DPF++ +     ++L       +R+  +++       N +   S   LQ        + +R P +GF+   I+A      LP +E  E    ++  LI+  ++ +    FP+Q  +W  G  L EP    L  N  P +  FR+   +  S++VV ND  W  L  SS+G+W G V+            LSV G FG+  D  +  +L YV+
Sbjct: 1540 LQRLIGNDEAIINVFLPNAGEYGLEVYANDSKKNGNSFYAVWQYFIVSSTAS---IVSG-LPSLQPGYLGPYEPKFSDYGLSTYSHKDPFIVANTGDICIQLKTTRDKPIRIMAQLI---HCSHNVSEMCSDQFLQLGRDSVVYFLIRLPHQGFFKFQIFA------LPYSEMGESLPGVFNYLIEGNQSSQYNVGFPQQFGQWKEGCYLYEPTNGVLGFNGKPDKITFRMDVMRAKSLAVVDNDNNWTHLEKSSDGIWTGDVDMRNIWKKPGKNELSVCGNFGMEADANYATILKYVI 1825

[Close]

BLAST of SWIM-type domain-containing protein vs. Planmine SMEST
Match: SMESG000080370.1 (SMESG000080370.1)

HSP 1 Score: 133.265 bits (334), Expect = 4.128e-31
Identity = 80/276 (28.99%), Postives = 135/276 (48.91%), Query Frame = 1

Query: 3190 VDNMVIEVMLLEPTTFTELVLYLTKDCSKDV-----EKVRAIFRWITTYDIKSVNFDPAA-PNDTLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMP----QAVGVSVKLENRTDGTILRGLTLAR 3987
            +D + I +     ++F  L+ +L  + +  +     +KV A+F W+TT ++  + F      +D+   VL  I  G+ +  ++F  +CRY G+ C+ I GY+KG  Y+PGM +   +  ++ W AV V   W   +C+W AR              L+ +T  S  +  K   D FYF+T+  Q  + HFP ++ WQL  + ITL++F  L +VK  FF  NL    +   VL+ +  K+ + I +P    + + ++  L     G I  G  L R
Sbjct:   95 LDELAITIGKHSFSSFIPLIYHLIYNRTDGIKCNEYQKVCALFTWLTTKNLHELKFSSETHASDSPEAVLLGISTGKTAYAQVFQMLCRYTGLQCKLIRGYAKGVDYKPGMKLGGGKEAQHAWNAVKVDNVWYLFDCHWAAR-------------RLMGKTINSDRI--KYDLDLFYFMTNPTQLRYTHFPFEEDWQLTKKKITLEEFEDLTLVKPTFFKYNLELYSHTQAVLEVQD-KLVLMIKLPIELVEKICLTFTLTLEGLGEIYEGSNLTR 354

[Close]

BLAST of SWIM-type domain-containing protein vs. Planmine SMEST
Match: SMESG000073008.1 (SMESG000073008.1)

HSP 1 Score: 131.724 bits (330), Expect = 1.551e-30
Identity = 76/265 (28.68%), Postives = 129/265 (48.68%), Query Frame = 1

Query: 3151 LKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKD---CSKDVEKVRAIFRWITTYDIKSVNFD-----PAAPND---TLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMP 3912
            ++ + ISP S  + D + + +   +  TF  LV  L  +      D++K RA+F W+T  +    +FD         ND   + +  L  +  GQ +  + F  +CR+AGI C+ + GY+KG  ++PGM ++  +  ++ W +V ++G W   + +W AR L  R+               +Q  +N  + D FYFL       + HFP  K WQL+  PI+L+ F  L IVK  FF   LSF   +  +++T    + +++  P
Sbjct:  108 IEQSRISP-SEKYFDPVALNLCQKKIVTFETLVFQLIHENPSVKTDLDKARAVFTWLTNINATEAHFDYINERKDFKNDEAESPIVYLHGLCTGQYTYAQFFQLLCRFAGIRCKLLRGYAKGNDFKPGMKLEGGKAAQHAWNSVEISGTWYLCDTHWTARRLAGRN--------------SNQGKQNSTQLDLFYFLIHPDDMKYSHFPFDKSWQLVPNPISLETFEKLAIVKPAFFRFELSFHNQFEAIVKT-NNDIKIELKFP 356

[Close]

BLAST of SWIM-type domain-containing protein vs. Planmine SMEST
Match: SMESG000073008.1 (SMESG000073008.1)

HSP 1 Score: 132.109 bits (331), Expect = 2.168e-30
Identity = 76/265 (28.68%), Postives = 129/265 (48.68%), Query Frame = 1

Query: 3151 LKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKD---CSKDVEKVRAIFRWITTYDIKSVNFD-----PAAPND---TLVGVLRAIKCGQMSNNELFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAWRFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDAKQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEVLQTKKGKVTVKINMP 3912
            ++ + ISP S  + D + + +   +  TF  LV  L  +      D++K RA+F W+T  +    +FD         ND   + +  L  +  GQ +  + F  +CR+AGI C+ + GY+KG  ++PGM ++  +  ++ W +V ++G W   + +W AR L  R+               +Q  +N  + D FYFL       + HFP  K WQL+  PI+L+ F  L IVK  FF   LSF   +  +++T    + +++  P
Sbjct:  734 IEQSRISP-SEKYFDPVALNLCQKKIVTFETLVFQLIHENPSVKTDLDKARAVFTWLTNINATEAHFDYINERKDFKNDEAESPIVYLHGLCTGQYTYAQFFQLLCRFAGIRCKLLRGYAKGNDFKPGMKLEGGKAAQHAWNSVEISGTWYLCDTHWTARRLAGRN--------------SNQGKQNSTQLDLFYFLIHPDDMKYSHFPFDKSWQLVPNPISLETFEKLAIVKPAFFRFELSFHNQFEAIVKT-NNDIKIELKFP 982

The following BLAST results are available for this feature:

BLAST of SWIM-type domain-containing protein vs. Ensembl Human
BLAST of SWIM-type domain-containing protein vs. Ensembl Celegans
BLAST of SWIM-type domain-containing protein vs. Ensembl Fly
BLAST of SWIM-type domain-containing protein vs. Ensembl Zebrafish
BLAST of SWIM-type domain-containing protein vs. Ensembl Xenopus
BLAST of SWIM-type domain-containing protein vs. Ensembl Mouse
BLAST of SWIM-type domain-containing protein vs. UniProt/SwissProt
BLAST of SWIM-type domain-containing protein vs. TrEMBL
BLAST of SWIM-type domain-containing protein vs. Ensembl Cavefish
BLAST of SWIM-type domain-containing protein vs. Ensembl Sea Lamprey
BLAST of SWIM-type domain-containing protein vs. Ensembl Yeast
BLAST of SWIM-type domain-containing protein vs. Ensembl Nematostella
BLAST of SWIM-type domain-containing protein vs. Ensembl Medaka
BLAST of SWIM-type domain-containing protein vs. Planmine SMEST

BLAST of SWIM-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3


Match Name	E-value	Identity	Description
KY	5.027e-28	26.38	kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:H...	[more]
KY	5.200e-28	35.68	kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:H...	[more]
KY	4.858e-16	37.90	kyphoscoliosis peptidase [Source:HGNC Symbol;Acc:H...	[more]

BLAST of SWIM-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ltd-1	7.347e-56	31.85	Lim and Transglutaminase Domain [Source:UniProtKB...	[more]
ltd-1	3.711e-54	32.21	Lim and Transglutaminase Domain [Source:UniProtKB...	[more]

BLAST of SWIM-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Hil	2.665e-64	34.68	gene:FBgn0050147 transcript:FBtr0086255	[more]
Hil	2.665e-64	34.68	gene:FBgn0050147 transcript:FBtr0086256	[more]

BLAST of SWIM-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ky	2.639e-23	26.73	kyphoscoliosis peptidase [Source:ZFIN;Acc:ZDB-GENE...	[more]
ky	4.905e-20	26.19	kyphoscoliosis peptidase [Source:ZFIN;Acc:ZDB-GENE...	[more]

BLAST of SWIM-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
cnpy1	1.701e-31	26.85	canopy FGF signaling regulator 1 [Source:Xenbase;A...	[more]
lmbr1	2.478e-30	26.28	limb development membrane protein 1 [Source:Xenbas...	[more]
ENSXETT00000026106.1	4.207e-9	30.13	kyphoscoliosis peptidase-like [Source:NCBI gene;Ac...	[more]
ENSXETT00000026111.1	5.101e-7	29.46	kyphoscoliosis peptidase-like [Source:NCBI gene;Ac...	[more]

BLAST of SWIM-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Ky	3.102e-28	35.06	kyphoscoliosis peptidase [Source:MGI Symbol;Acc:MG...	[more]

BLAST of SWIM-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 3


Match Name	E-value	Identity	Description
sp\|Q0E908\|HIL_DROME	2.671e-63	34.68	Hillarin OS=Drosophila melanogaster OX=7227 GN=Hil...	[more]
sp\|Q8NBH2\|KY_HUMAN	1.515e-28	26.19	Kyphoscoliosis peptidase OS=Homo sapiens OX=9606 G...	[more]
sp\|Q8C8H8\|KY_MOUSE	2.287e-27	35.06	Kyphoscoliosis peptidase OS=Mus musculus OX=10090 ...	[more]

BLAST of SWIM-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267DV76	3.057e-161	43.53	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267E954	1.285e-157	44.17	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267G4V6	5.219e-157	44.02	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267EBZ4	5.366e-157	44.02	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A430QMV6	2.620e-156	47.16	Uncharacterized protein OS=Schistosoma bovis OX=61...	[more]

BLAST of SWIM-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ky	1.708e-26	26.20	uncharacterized LOC103044048 [Source:NCBI gene;Acc...	[more]
ky	1.708e-26	26.20	uncharacterized LOC103044048 [Source:NCBI gene;Acc...	[more]
ENSAMXT00000032424.1	5.393e-22	24.58	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000040397.1	7.038e-22	24.50	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of SWIM-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000009155.1	1.058e-16	27.72	pep scaffold:Pmarinus_7.0:GL483885:156116:165500:-...	[more]

BLAST of SWIM-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of SWIM-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO40037	8.285e-11	21.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32609	4.251e-10	21.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SWIM-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ky	1.945e-24	24.34	kyphoscoliosis peptidase [Source:NCBI gene;Acc:101...	[more]
ky	7.697e-24	24.76	kyphoscoliosis peptidase [Source:NCBI gene;Acc:101...	[more]

BLAST of SWIM-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000060198.1	0.000e+0	99.94	SMESG000060198.1	[more]
SMESG000061907.1	3.137e-39	30.28	SMESG000061907.1	[more]
SMESG000080370.1	4.128e-31	28.99	SMESG000080370.1	[more]
SMESG000073008.1	1.551e-30	28.68	SMESG000073008.1	[more]
SMESG000073008.1	2.168e-30	28.68	SMESG000073008.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30026870 ID=SMED30026870|Name=SWIM-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=5032bp
AGTTCATGCTCCGGAAATTTTCATGAAAATAATTCAGTAGTTGTCTTCAT
TTTATCTTAATTGTAATTTAAAAGAATTATGTACAGTTAAGGTTGATTTA
AGCTCAATTCATTAACAATGTCATTTAACAATTCTCATCACATTGAAAAT
GTCAAGTTATTCACAAATCGCTTTCCCAGAAAGAGTCAAGAAAAAATTTA
TCACGAAGAAATCGAAGATTTTGATTCATCAGAATCATCTGAATCTTCTT
ACGATTGCACTTCCGATGGCTCGTCAAGTTCTGATGAGTTCGTAATACTG
GATGACTACACAACTCTTAAAACAGAATTAAAAAATAATCAAATATCTCC
AAGTATCCTAAAACGTCTTTCCAAGAATCAAAAAAGCAATAAAAAAAATG
TCAATCATCCTCTGTTATCAACTAAAACAAAATCTCTACCAATTATTTTC
GAAAGATCTGACGAAAGTTCTGTCAGTTCACAAAGTACACTAGAGTTATC
AGAAAACGAATCGACGCTTTCTGATTGCTCAACTTCATCATCTTCAGTAT
TAGCCAATGAAATGAATTCTAAAAATTCGAATGAGATATTAATTCTAAAT
CAATCCAATTCTTCTGAGATTACAAACAATTCATACCAAAATAGCGTTTC
ACAACTACAGCATAATCAACCAATCAGAATTAAGAAAACCAATTCTATCG
ATTCCAGTAATAAAATATCACCTGCTCTTTTAATTGTAGATGATAATTCT
AATAATGATTTTAAAATGTGTGACTCATTGAATGGTAATCAAACGACGAT
GTGTAATAATAATGCTACGACATTACACACACACAATTCTAGTTCAATTG
CGGATTTAGATATGGCACACCAATTTATCGGTGTGCCAGAATGGACCAAG
ATCAATAAATCATCAAATTCATTATCTCAGTCAACAGAGTTGATTTTCAA
CAAGCGAACTCCGAGATTTCCAGTGAAAAATAATTCCAATACAGTTGAAA
ACAGTGAAAATAAACATTTATTAATACCGGATCAATTTGAATGTGAAAAT
ACAATGAAAAATTATCAATATCAGCAGAAAAAGCCGCCTGTCTCTGTGAA
ACCCGTTGAGAAATTGGAAAACAACAATTTGAGAATTTCAAACAAAATAC
CTCCAAATGAAACTCCAAATGAAACTATTTTGGATCATCAAAAGAAACCA
CCAGTTGGAAGAAAACCGAAAAATGAAAAAGAACACACCGAACCAACTAC
GGATTTGGATGATCTGATTGAAGGCCATCATCGCAATTCTAATGAAAGTT
TGGAATTATCATCGTCTTCAGCCAGTCACAGTTCCGGTGGGAATGAACCG
GCAAAAACTGAGAGTTATTTTAAAAAGGAAATGTTGAAAAATTATACAAA
AACCGATTTAATAATAATGCCCATTAAAACTCAACAAAATAGCGCTAGTA
ACAATCGTTTATATGAGAAAAAACAAGATCAAGGTAAAGTGGAAAATACG
AAAACGAAACCTTCTGAAACAATCGGATTATTGTCGTATCAAAAGGATAG
CCCAAGTAAAAGATCTCAGGAACTTGTGGGCAGTGTTGTAAAAATGGATA
AAACAATAAATCGAGTAACAAACAACATCGAGAGAATTGATAATGCAATA
GATAAATTGTCTCAATTTAACAAAGCATACATGTCCAATCTTGAAACAAT
GTCAGACTCTGAATTAAGTATAGATTTCGAGACCCATAGCATAGGAGCTC
AGACAGATTTATCGAATCCAAATTACCACGAAAAATCATCAGAGAATTCT
AATAAAGTTCAAGAAAATTCAAACAATAAATATCCAAAGAATTCCTCGAA
AATTACCCCTGAAAATGAATCTTCCAGTTCCGATGAATCGTCTACCGAAA
AGGAAACAAGTTCCGAAAGTGAAAATTCAGTCGCATTGAAACCGTCTCCA
GTTCATCAAATCATTGACAAACCGATTATAAAGTTCCGTTCCAGTAGTCC
TGGTTACAAATCATCTCCTTCTAAACCGATATTGGATTCAAAAACTGATG
GGAATAAATTCTTTCGAACTTCAAACTTAGCTCACACAGAATCTGATGTT
TCCTCATTACCAGAATCATCTGTGTGTGAAAATCCAGAAACCCGAGATCT
GGTTGGCAAGGTGAAATATTTTCAAAGACAGATAATAAAATCATCGGGCC
TCTACAAAAAACCACCAAACATTGAACCGCCGAAAAAATTAGTCGTTGAA
GAACCACATCTGAAAGTTCAATCTTCTCAACGACCGATTCCTAAGCCTCG
TAATAGTATAGATTATGCTTTACGTCGCATGAGCAATTCTTCATCGGAAT
CATCCAATTTTGATTTCAATGGAAAGACTCTCTCGAATTCCAACAATCAT
ACACAAATTAGCCCTTCCCCAGGAAACAGTGACAGCGGATCGATTATAAG
CCTAGGCAGTAATCATTTGGAACGTAAATTTCAAAAAGGTGCTGGAGCAA
GTGCTAGATATAATACAAAATCCAAACCAAATGACAAATGGGGAACAGTT
GGATCGAGAAGGTCTCAAAAATCAAAACCGGAAGAAGAGTGTGCTTCTCT
GTCTGGTAGACCGATGCCAAATAAAAATCAGATGAAAATTTACATGAACC
AAAGTCGATCATACAATAACTTAAATTCCTTAAATTCGAAGAATCCCGAT
GAAAAATCAAAATATGGAAGTCTGGCAGCATTAAACAAGAATTACGGTTT
ACAAGATATCAACAGCCTTTGTGACATAATCCGCCAGAATCTCAATCTCA
ATAACCATGACAAAATAAGAAACATTTTTAATGCTTTAATCATTGAAAAT
GAACACGATAAAATTGATGTCATTATTGATAATTTTGAAGAAAATGAAAG
AAATATTTTATTGGAATTAATTCCCGACAATCATTATACTTCGAAAGACG
CCGAGTCGATCTTTGATATGACAATGTCTCGAACAGATTTGCACAATCAC
CTGAGACCGGGATTAAGCATGTCCAGTTTGAGCGATGCTTATTATCAGCA
TACACTCGACAACGATCGAATGGTTTATTGGAGAGCTGACATCGAAGAAC
TTTTACCCCCTCCCATGAAACCGCCCCCTAAGCCAATGCCTACCAACCTT
TTGAAATCAGCTATCATTAGTCCAGAGTCATTGATTCATGTTGACAATAT
GGTGATTGAGGTGATGTTATTAGAACCAACCACATTCACAGAATTAGTGT
TATACCTTACCAAAGATTGTTCCAAAGACGTGGAAAAAGTTCGGGCTATT
TTTCGATGGATAACTACATATGACATAAAATCTGTTAATTTTGACCCAGC
TGCCCCTAATGACACTTTGGTGGGAGTTTTACGTGCAATAAAATGCGGTC
AAATGAGTAATAATGAATTATTTTTTCGAATGTGCAGATATGCTGGAATA
CATTGTCAATTTATATCTGGTTATAGTAAAGGTGCTGGTTATCGGCCGGG
AATGGCTATTAAAGATAACAGGATGTTTAGAAACGTTTGGACTGCTGTTT
ATGTTGCTGGTGCTTGGCGGTTTGTAAATTGCAATTGGGGTGCTAGATAT
CTCACAAGCAGACATCAAGAACTTCCTTCTAGTGGAACTCTCTTATCTCG
TACATCTCAATCTCAGTATTTGGAAAATAAAATCCGTAGCGATGAATTCT
ATTTTCTCACCGACGCCAAACAACATATATTTGAGCATTTCCCAGATAAA
AAGCGATGGCAGTTACTTACAAGACCAATAACACTTGATCAATTTATGGC
TCTTCCCATTGTAAAATCACCGTTTTTCAACGCTAATTTGTCTTTCAAAC
GAAATTATGCTGAAGTTCTTCAAACAAAAAAAGGAAAAGTTACTGTTAAA
ATAAATATGCCCCAAGCTGTTGGAGTCAGTGTAAAATTAGAAAATCGCAC
TGACGGGACGATTCTTAGAGGCTTGACTTTAGCTAGAATTCTCGACGGTC
AAATGATTGTAGTGACTGCTTCTCCGTCTCAACCGGGAAAATTCTATTTA
AGTATATATGTGAATGAAGATTGGAAATCTGAGGATAATATGGAAATGGC
ATGTTCTTTTCAAGTTCATTGTTCTGAACATAATTATGATCGGTTGGTTA
CTGGGAGATTTCCGGATGTTGGTGTTCTAGGTTCGACTCCTGCATCGCAA
AATCTCGGAATCATTGCTAATCCTGGAGTCGACCCTTTTGTTTTATGGGA
TGAGCGATCTACACTGAAATTGAATATTGCAATTAGACCTGGTCTTAGAG
TAGGGCAAAAAATGATGTCTTATGATAGGTCTGGTCAAAATTCAGCTCCT
TGTGATAGTTATGCGTTATTACAGTACCAAAGTCAAGGCCGTAGTCAATA
TCATCTGAGATTTCCAATTGAAGGATTTTATTGTTTAACAATTTATGCTG
GAGTTGATGATCCTGATCTTCCAGATACCGAGCCAATGGAATGTATTTAT
AGACTGTTAATTGATTGTAAACGAGCTCAAGAACGAATACCTCCTTTTCC
TCGACAAACTAGTCGCTGGGTGGGATTCAGATTAGTTGAGCCTTTGTGCC
AACATTTAGAGCTCAACACTCCTTATCGGTTCAGAATTTTAGCTGCACAA
TGTTCATCGGTATCAGTGGTGATTAATGACACCAAGTGGGTGGACTTGGC
GGTTTCTAGTAATGGGCTGTGGAAAGGCAAAGTTAATACTGGGCAAGAGT
TGGAAAATTTATCGGTTTACGGTAAATTTGGCATCAATGAAGATGATGAA
TTCATCAAATTGCTGGATTACGTATTAATAGCGAAATCGAACAAGTGATT
TATTATTCATGGTGGCGATGTTCGTGTTTACATGTACATATTTCTAATTT
TCACATATCTGTTCCAAACATATCATTCCTTCCAGACGATCAAATGCTCT
TTTTAGAGGATTATGTTAATCATTTTGTATTTATGAAATAAATGTATCTA
TTTTTTTCAATAAATCATTGTTAATAACTGGC

protein sequence of SMED30026870-orf-1

>SMED30026870-orf-1 ID=SMED30026870-orf-1|Name=SMED30026870-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1577bp
MSFNNSHHIENVKLFTNRFPRKSQEKIYHEEIEDFDSSESSESSYDCTSD
GSSSSDEFVILDDYTTLKTELKNNQISPSILKRLSKNQKSNKKNVNHPLL
STKTKSLPIIFERSDESSVSSQSTLELSENESTLSDCSTSSSSVLANEMN
SKNSNEILILNQSNSSEITNNSYQNSVSQLQHNQPIRIKKTNSIDSSNKI
SPALLIVDDNSNNDFKMCDSLNGNQTTMCNNNATTLHTHNSSSIADLDMA
HQFIGVPEWTKINKSSNSLSQSTELIFNKRTPRFPVKNNSNTVENSENKH
LLIPDQFECENTMKNYQYQQKKPPVSVKPVEKLENNNLRISNKIPPNETP
NETILDHQKKPPVGRKPKNEKEHTEPTTDLDDLIEGHHRNSNESLELSSS
SASHSSGGNEPAKTESYFKKEMLKNYTKTDLIIMPIKTQQNSASNNRLYE
KKQDQGKVENTKTKPSETIGLLSYQKDSPSKRSQELVGSVVKMDKTINRV
TNNIERIDNAIDKLSQFNKAYMSNLETMSDSELSIDFETHSIGAQTDLSN
PNYHEKSSENSNKVQENSNNKYPKNSSKITPENESSSSDESSTEKETSSE
SENSVALKPSPVHQIIDKPIIKFRSSSPGYKSSPSKPILDSKTDGNKFFR
TSNLAHTESDVSSLPESSVCENPETRDLVGKVKYFQRQIIKSSGLYKKPP
NIEPPKKLVVEEPHLKVQSSQRPIPKPRNSIDYALRRMSNSSSESSNFDF
NGKTLSNSNNHTQISPSPGNSDSGSIISLGSNHLERKFQKGAGASARYNT
KSKPNDKWGTVGSRRSQKSKPEEECASLSGRPMPNKNQMKIYMNQSRSYN
NLNSLNSKNPDEKSKYGSLAALNKNYGLQDINSLCDIIRQNLNLNNHDKI
RNIFNALIIENEHDKIDVIIDNFEENERNILLELIPDNHYTSKDAESIFD
MTMSRTDLHNHLRPGLSMSSLSDAYYQHTLDNDRMVYWRADIEELLPPPM
KPPPKPMPTNLLKSAIISPESLIHVDNMVIEVMLLEPTTFTELVLYLTKD
CSKDVEKVRAIFRWITTYDIKSVNFDPAAPNDTLVGVLRAIKCGQMSNNE
LFFRMCRYAGIHCQFISGYSKGAGYRPGMAIKDNRMFRNVWTAVYVAGAW
RFVNCNWGARYLTSRHQELPSSGTLLSRTSQSQYLENKIRSDEFYFLTDA
KQHIFEHFPDKKRWQLLTRPITLDQFMALPIVKSPFFNANLSFKRNYAEV
LQTKKGKVTVKINMPQAVGVSVKLENRTDGTILRGLTLARILDGQMIVVT
ASPSQPGKFYLSIYVNEDWKSEDNMEMACSFQVHCSEHNYDRLVTGRFPD
VGVLGSTPASQNLGIIANPGVDPFVLWDERSTLKLNIAIRPGLRVGQKMM
SYDRSGQNSAPCDSYALLQYQSQGRSQYHLRFPIEGFYCLTIYAGVDDPD
LPDTEPMECIYRLLIDCKRAQERIPPFPRQTSRWVGFRLVEPLCQHLELN
TPYRFRILAAQCSSVSVVINDTKWVDLAVSSNGLWKGKVNTGQELENLSV
YGKFGINEDDEFIKLLDYVLIAKSNK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000016	pharynx
PLANA:0000020	protonephridia
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0000099	neuron
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR038765	Papain-like_cys_pep_sf
IPR001678	MeTrfase_RsmB/NOP2
IPR002931	Transglutaminase-like

Vocabulary: **molecular function**
Term	Definition
GO:0008168	methyltransferase activity
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002931	Transglutaminase-like	SMART	SM00460	TG_5	coord: 1087..1157 e-value: 0.0081 score: 23.6
IPR002931	Transglutaminase-like	PFAM	PF01841	Transglut_core	coord: 1045..1150 e-value: 1.0E-5 score: 25.9
None	No IPR available	GENE3D	G3DSA:3.10.620.30		coord: 1018..1162 e-value: 6.4E-6 score: 27.6
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 795..815
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 546..644
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 546..587
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 336..352
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 336..416
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 353..392
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 626..644
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 31..50
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 393..412
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 791..837
None	No IPR available	PANTHER	PTHR47020	FAMILY NOT NAMED	coord: 278..1268 coord: 1275..1567
IPR038765	Papain-like cysteine peptidase superfamily	SUPERFAMILY	SSF54001	Cysteine proteinases	coord: 1040..1160

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SWIM-type domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 13

Owlery

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