Phosphodiesterase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30026857 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE11A (phosphodiesterase 11A [Source:HGNC Symbol;Acc:HGNC:8773]) HSP 1 Score: 439.499 bits (1129), Expect = 3.097e-146 Identity = 225/546 (41.21%), Postives = 332/546 (60.81%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
C + NA LF E+ R++ LLE +++L+EEQ LEK +KK +H+ + ++KCE +V LL+ F C+ + EN F + EK + + IA++V G ++++ + + + D++ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S EV IP S + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV +M +L +L ++EIL +IVGCLCHDLDHRGTNN FQ K+ S LAQLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R +FF V DW R + R LMT+CDL A TK W ++++ A LV EFF+QGD E+ K+ P + DR+ +DELP +Q++WI S+C PL++ L V+ + + M D + N W EL K
Sbjct: 8 CGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQK 553
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE11A (phosphodiesterase 11A [Source:NCBI gene;Acc:50940]) HSP 1 Score: 440.269 bits (1131), Expect = 4.944e-145 Identity = 225/546 (41.21%), Postives = 332/546 (60.81%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
C + NA LF E+ R++ LLE +++L+EEQ LEK +KK +H+ + ++KCE +V LL+ F C+ + EN F + EK + + IA++V G ++++ + + + D++ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S EV IP S + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV +M +L +L ++EIL +IVGCLCHDLDHRGTNN FQ K+ S LAQLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R +FF V DW R + R LMT+CDL A TK W ++++ A LV EFF+QGD E+ K+ P + DR+ +DELP +Q++WI S+C PL++ L V+ + + M D + N W EL K
Sbjct: 116 CGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQK 661 HSP 2 Score: 58.9214 bits (141), Expect = 2.736e-8 Identity = 35/122 (28.69%), Postives = 59/122 (48.36%), Query Frame = 3
Query: 681 KIAKMVCINGESFKCKSE-------------------EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
KI ++V I+G S K E +++D+L S++C PI S +IG AQ INK+ F+++DE +M+ FC + I+N +L+ K R++ LE ++
Sbjct: 23 KITRLVQISGASLAEKQEKHQDFLIQRQTKTKDRRFNDEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVN 144
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE11A (phosphodiesterase 11A [Source:HGNC Symbol;Acc:HGNC:8773]) HSP 1 Score: 439.499 bits (1129), Expect = 8.144e-142 Identity = 225/546 (41.21%), Postives = 332/546 (60.81%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
C + NA LF E+ R++ LLE +++L+EEQ LEK +KK +H+ + ++KCE +V LL+ F C+ + EN F + EK + + IA++V G ++++ + + + D++ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S EV IP S + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV +M +L +L ++EIL +IVGCLCHDLDHRGTNN FQ K+ S LAQLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R +FF V DW R + R LMT+CDL A TK W ++++ A LV EFF+QGD E+ K+ P + DR+ +DELP +Q++WI S+C PL++ L V+ + + M D + N W EL K
Sbjct: 366 CGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQK 911 HSP 2 Score: 56.9954 bits (136), Expect = 1.210e-7 Identity = 27/85 (31.76%), Postives = 48/85 (56.47%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C PI S +IG AQ INK+ F+++DE +M+ FC + I+N +L+ K R++ LE ++
Sbjct: 310 DEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVN 394
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE11A (phosphodiesterase 11A [Source:HGNC Symbol;Acc:HGNC:8773]) HSP 1 Score: 395.586 bits (1015), Expect = 2.249e-130 Identity = 198/463 (42.76%), Postives = 289/463 (62.42%), Query Frame = 3
Query: 624 CTLNTENKFSLTSEK------IGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
C+ + EN F + EK + + IA++V G ++++ + + + D++ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S EV IP S + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV +M +L +L ++EIL +IVGCLCHDLDHRGTNN FQ K+ S LAQLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R +FF V DW R + R LMT+CDL A TK W ++++ A LV EFF+QGD E+ K+ P + DR+ +DELP +Q++WI S+C PL++ L V+ + + M D + N W EL K
Sbjct: 5 CSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQK 467
BLAST of Phosphodiesterase vs. Ensembl Human
Match: PDE5A (phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784]) HSP 1 Score: 343.969 bits (881), Expect = 1.506e-106 Identity = 198/553 (35.80%), Postives = 311/553 (56.24%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDV-CAEKPSN-FGFHCTLNTENKFSLTSEKIGSR---KIAKMVCINGESFKCK----------SEEKLDELKEIGISSMICKPIWDSS-NHVIGAAQVINKLE------RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTAS---LTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPE 1976
C L+NA L+ET E RN+VLL+ ++EEQ SLE +KK + ++ ++ +F++D C++ S+ F C ++ +LT E ++ A+ V E + E + + I S++C PI + N VIG Q++NK+E + F++NDE +EA IFC +GI N ++YE + ++ A+ V LE LSYH +A+ E+ + +PS T ++ F+DF LS+ E L T+++F DL ++ F +K E L +W+++V KNYR NVAYHNW HAFN M L + L D+EIL L++ L HDLDHRG NN++ +++ PLAQLY + + +E HHF+ +MI+N+ GN I L+ ++Y T + IIKQ+ILATDL+ + K R +FF + + Q++L LMT+CDL+A TK WP+ Q+ A LV EFF QGD E+ I+P +M+R ++++P +Q+ +I ++C L+ LT V + + D +N W L + E
Sbjct: 258 CGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVDEDCSDSFSSVFHMECEELEKSSDTLTREHDANKINYMYAQYVKNTMEPLNIPDVSKDKRFPWTTENTGNVNQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKVKPFNRNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLEILALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCH-SIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQGDRERKELNIEPTDLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNRQKWQALAEQQE 809
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-5 (Probable 3',5'-cyclic phosphodiesterase pde-5 [Source:UniProtKB/Swiss-Prot;Acc:P91119]) HSP 1 Score: 257.684 bits (657), Expect = 1.678e-75 Identity = 160/512 (31.25%), Postives = 262/512 (51.17%), Query Frame = 3
Query: 465 LLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIG------SRKIAKMVCINGESFKCKS---EEK----LDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
LL+ ++ + S++ + K ++ ++++ + ++FL+D + F E + SE S+ IA V GE ++ +E+ +D +++C PI VIG Q++NK + F++ DED E ++C + + + +LY+ + +S + +VALE L+YH+ + EV+ + + I + +L + FN LS E L V +F L TL E L ++V+TV KNYR VAYHNW H ++V H M L +E L L V CLCHDLDHRG NN + +PLA +Y + +E+HHFN TV I+ DG+NI +SL+++ Y +S+IK ILATDL+ F + K ++N D E R L + +MT CDL A+ K W + + ++ EEF+ QGD E+ + +P MMDR LP++Q+ ++ +C P + + + + +M ++ N W EL
Sbjct: 201 LLDVARSIFHDIVSMDAVIIKVMNFAQKLVDADRASLFLVDSKNAQIYARIFDVGTGDEEHVRVNSEGQKEIRFDMSKGIAGYVASTGEGLNIENAYEDERFNADVDSKTGYTTKTILCMPIL-IRGIVIGVVQMVNKHDGVFTRQDEDAFEIFAVYCGLALHHAKLYDKIRRSEQKYRVALEVLAYHSVCNADEVNKLKKIEINN-RIVELETIDFNGMRLSELEKPLYAVYMFKTLFADTL-RFDTEDLIRFVLTVRKNYRRVAYHNWAHGWSVAHAMFATLMNSP--DAFTKLEALALYVSCLCHDLDHRGKNNAYMKTMSTPLASIYST-SVMERHHFNQTVTILQQDGHNILKSLSSEDYKKTLSLIKHCILATDLALFFSNKAKLNVILDNNTFDINRQEHRLLTQAVMMTGCDLVASAKPWNIQTETVKVIFEEFYDQGDAER-LSGKEPIPMMDRQQAHMLPQMQVGFMRGICMPCYDLIARIFPKNDKMRERCEYNAKKWEEL 705
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-2 (Probable 3',5'-cyclic phosphodiesterase pde-2 [Source:UniProtKB/Swiss-Prot;Acc:P30645]) HSP 1 Score: 194.897 bits (494), Expect = 2.264e-52 Identity = 147/500 (29.40%), Postives = 254/500 (50.80%), Query Frame = 3
Query: 501 NSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAK-MVCIN-GESFKCKS-EEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVH--HIMEKPIPSFSTSQLGSHKFNDFSLSNEEMV-----LATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKT--DSPLAQLYGNQAT-LEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
N+L + + + K+ + E+ AVFL D ++ F L T KF + +G K+A M +N + +C E++DE I ++I P+ DSS +IG + NK E FS++DE ++ + F I + L + + + R + E A + EV ++ P+ + + S F DFS + A++ F DL L+ + + L V+ V YR V YHNW HAF V H L ++ + L D+E L L++ CLCHD+DHRGT N+FQ+++ +PL+ LY + + LE+HHF T+ ++ + +I E+L + T+++ I++ ILATD+S H + +E+ + + ++ + S + R LL +MT+ DL+ K + A++ A + EFF QGD+E + ++P MMDR+ +P +QI ++ + P+F+ L V + + + + N + W L
Sbjct: 176 NNLSALISCIIAEAKKNTEAEDYAVFLHDEDNKQMVLFNNETMLMTGKKFDMGYGIVG--KVASTMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNK-ENGFSRHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDW---RYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSAGYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISAHLRKQERIKTMI-SEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQL-GVKPLEMMDRT-NAYVPTVQIDFLFKIGVPVFQLLASVVPEGRTTSEAIDANHLCWVAL 666
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-2 (Probable 3',5'-cyclic phosphodiesterase pde-2 [Source:UniProtKB/Swiss-Prot;Acc:P30645]) HSP 1 Score: 194.512 bits (493), Expect = 2.861e-52 Identity = 147/500 (29.40%), Postives = 254/500 (50.80%), Query Frame = 3
Query: 501 NSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAK-MVCIN-GESFKCKS-EEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVH--HIMEKPIPSFSTSQLGSHKFNDFSLSNEEMV-----LATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKT--DSPLAQLYGNQAT-LEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
N+L + + + K+ + E+ AVFL D ++ F L T KF + +G K+A M +N + +C E++DE I ++I P+ DSS +IG + NK E FS++DE ++ + F I + L + + + R + E A + EV ++ P+ + + S F DFS + A++ F DL L+ + + L V+ V YR V YHNW HAF V H L ++ + L D+E L L++ CLCHD+DHRGT N+FQ+++ +PL+ LY + + LE+HHF T+ ++ + +I E+L + T+++ I++ ILATD+S H + +E+ + + ++ + S + R LL +MT+ DL+ K + A++ A + EFF QGD+E + ++P MMDR+ +P +QI ++ + P+F+ L V + + + + N + W L
Sbjct: 173 NNLSALISCIIAEAKKNTEAEDYAVFLHDEDNKQMVLFNNETMLMTGKKFDMGYGIVG--KVASTMRTMNIRDVSRCPFFNEEIDEQFSIKARNLIAFPLIDSSCSLIGVIVLYNK-ENGFSRHDEKYIKRFSYFVANSIAHAILAKQIEEVRTRIHMVEEFKIQGEDAVIEEVDIMRLVNDPLRDW---RYFSQNFADFSFPPRSVGENHFHRASMMFFEDLGFSMLYKLNKRKLSYLVLRVSAGYRPVPYHNWSHAFAVTHFCWLTLRTDAIRRALSDMERLSLLIACLCHDIDHRGTTNSFQMQSLQKTPLSVLYSTEGSVLERHHFAQTIKLLQQEECSILENLPAADFRTIVNTIREVILATDISAHLRKQERIKTMI-SEGYNPMSFDHRYLLMCLVMTASDLSDQAKNFHNAKRIAENIYLEFFAQGDLELQL-GVKPLEMMDRT-NAYVPTVQIDFLFKIGVPVFQLLASVVPEGRTTSEAIDANHLCWVAL 663
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-1 (Probable 3',5'-cyclic phosphodiesterase pde-1 [Source:UniProtKB/Swiss-Prot;Acc:O18696]) HSP 1 Score: 117.857 bits (294), Expect = 1.241e-27 Identity = 76/245 (31.02%), Postives = 126/245 (51.43%), Query Frame = 3
Query: 1179 YKWVITVMKNY----------RNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHF---KTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEP 1874
+K +T ++NY N YHN HA +V ++L + + L D+E+L ++ G L HD +H G NNF I++ S A LY +++ LE HH + +M D NI LT D+Y L +++ + +LATD+S HF KT + S E ++ K L ++ +CD++ K W + ++ V+EEFF+QGD+E ++ + + DR + + QI +I + EP
Sbjct: 176 FKVPLTALENYLSALEVGYSKHNNPYHNVVHAADVTQSSHFMLSQTGLANSLGDLELLAVLFGALIHDYEHTGHTNNFHIQSQSQFAMLYNDRSVLENHHVSSCFRLMKEDDKNILTHLTRDEYKELRNMVIEIVLATDMSTHFMQIKTMKSMLSLPE-------GIDKNKALC-LIVHACDISHPAKPWNLHERWTEGVLEEFFRQGDLEASM-GLPYSPLCDRHTV-HVADSQIGFIDFIVEP 410
BLAST of Phosphodiesterase vs. Ensembl Celegans
Match: pde-1 (Probable 3',5'-cyclic phosphodiesterase pde-1 [Source:UniProtKB/Swiss-Prot;Acc:O18696]) HSP 1 Score: 118.242 bits (295), Expect = 2.061e-27 Identity = 76/245 (31.02%), Postives = 126/245 (51.43%), Query Frame = 3
Query: 1179 YKWVITVMKNY----------RNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHF---KTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEP 1874
+K +T ++NY N YHN HA +V ++L + + L D+E+L ++ G L HD +H G NNF I++ S A LY +++ LE HH + +M D NI LT D+Y L +++ + +LATD+S HF KT + S E ++ K L ++ +CD++ K W + ++ V+EEFF+QGD+E ++ + + DR + + QI +I + EP
Sbjct: 307 FKVPLTALENYLSALEVGYSKHNNPYHNVVHAADVTQSSHFMLSQTGLANSLGDLELLAVLFGALIHDYEHTGHTNNFHIQSQSQFAMLYNDRSVLENHHVSSCFRLMKEDDKNILTHLTRDEYKELRNMVIEIVLATDMSTHFMQIKTMKSMLSLPE-------GIDKNKALC-LIVHACDISHPAKPWNLHERWTEGVLEEFFRQGDLEASM-GLPYSPLCDRHTV-HVADSQIGFIDFIVEP 541
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde6 (gene:FBgn0038237 transcript:FBtr0300330) HSP 1 Score: 394.43 bits (1012), Expect = 3.621e-123 Identity = 220/580 (37.93%), Postives = 328/580 (56.55%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFL--LDVCA--------EKPSNFGFHCTLNTE--------NKFSLTSEKIG-------SR------------KIAKMVCINGESF-------------KCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLER-DFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
C G+ NA LFE E+ RN++LL ++EEQN+LE + K + + +E++KCE +VFL LD C EKP+ + + N+F++ E G SR +IA+ V G++ + ++E+++D + I +C PI ++ VIG AQ+INK F+ +D I EA IFC +GI N ++YE+ K A+ +VALE LSYH TAS + + + I + L S F DF L +++ A +++F+ +++ F I + L +WV++V KNYR V YHNW HA NV M +L + + + D+EILGL+V CLCHDLDHRGTNN FQ KT+SPLA LY +T+E HHF+ VMI+N++GNNIF++L+ + Y ++M ++ +IL+TDL+ +FK R F VEN DW+ E++ LL +MT+CD++A K W V K A LV +EFF QGD+EK QP MMDR +DELP++Q+ +I +C PL+R L +Y+ +EN +W +L K E+
Sbjct: 395 CGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEASHLEKIIEKPNQPATRAIKSADSFEEKKMRNRFTVLFELGGEYQAANVSRPSVSELSSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQIRAEDEIDSTQAI-----LCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQDVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-TTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLAEKVEMG 968
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde6 (gene:FBgn0038237 transcript:FBtr0345168) HSP 1 Score: 394.43 bits (1012), Expect = 3.621e-123 Identity = 220/580 (37.93%), Postives = 328/580 (56.55%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFL--LDVCA--------EKPSNFGFHCTLNTE--------NKFSLTSEKIG-------SR------------KIAKMVCINGESF-------------KCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLER-DFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
C G+ NA LFE E+ RN++LL ++EEQN+LE + K + + +E++KCE +VFL LD C EKP+ + + N+F++ E G SR +IA+ V G++ + ++E+++D + I +C PI ++ VIG AQ+INK F+ +D I EA IFC +GI N ++YE+ K A+ +VALE LSYH TAS + + + I + L S F DF L +++ A +++F+ +++ F I + L +WV++V KNYR V YHNW HA NV M +L + + + D+EILGL+V CLCHDLDHRGTNN FQ KT+SPLA LY +T+E HHF+ VMI+N++GNNIF++L+ + Y ++M ++ +IL+TDL+ +FK R F VEN DW+ E++ LL +MT+CD++A K W V K A LV +EFF QGD+EK QP MMDR +DELP++Q+ +I +C PL+R L +Y+ +EN +W +L K E+
Sbjct: 395 CGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEASHLEKIIEKPNQPATRAIKSADSFEEKKMRNRFTVLFELGGEYQAANVSRPSVSELSSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQIRAEDEIDSTQAI-----LCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQDVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-TTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLAEKVEMG 968
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde6 (gene:FBgn0038237 transcript:FBtr0330048) HSP 1 Score: 394.045 bits (1011), Expect = 4.936e-123 Identity = 220/580 (37.93%), Postives = 328/580 (56.55%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFL--LDVCA--------EKPSNFGFHCTLNTE--------NKFSLTSEKIG-------SR------------KIAKMVCINGESF-------------KCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLER-DFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
C G+ NA LFE E+ RN++LL ++EEQN+LE + K + + +E++KCE +VFL LD C EKP+ + + N+F++ E G SR +IA+ V G++ + ++E+++D + I +C PI ++ VIG AQ+INK F+ +D I EA IFC +GI N ++YE+ K A+ +VALE LSYH TAS + + + I + L S F DF L +++ A +++F+ +++ F I + L +WV++V KNYR V YHNW HA NV M +L + + + D+EILGL+V CLCHDLDHRGTNN FQ KT+SPLA LY +T+E HHF+ VMI+N++GNNIF++L+ + Y ++M ++ +IL+TDL+ +FK R F VEN DW+ E++ LL +MT+CD++A K W V K A LV +EFF QGD+EK QP MMDR +DELP++Q+ +I +C PL+R L +Y+ +EN +W +L K E+
Sbjct: 395 CGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEASHLEKIIEKPNQPATRAIKSADSFEEKKMRNRFTVLFELGGEYQAANVSRPSVSELSSSTLAQIAQFVATTGQTVNICDVIEWVRDHNQIRAEDEIDSTQAI-----LCMPIMNAQKKVIGVAQLINKANGVPFTDSDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATASQDQTEKLTQDVIAEAESYNLYSFTFTDFELVDDDTCRAVLRMFMQCNLVSQFQIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-TTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHKVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLAEKVEMG 968
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0303163) HSP 1 Score: 384.8 bits (987), Expect = 1.295e-119 Identity = 207/545 (37.98%), Postives = 315/545 (57.80%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPS---NFGFHCTLNTENKFSLTSEKIGSR-----KIAKMVCINGESFKCKS-------EEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKL-ERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
+ + Q C GL NA L+E E RN+VLL+ ++EEQ+++E + + + M+ +I+C+ V + L+ A+K S F F +E + + + SR I V GE+ + + +DE S++C I +S +IG Q+INK E DF+KNDE+ +EA IFC +GI N +YE + A+ V LE LSYH +A++ E H + +PS +L KF+D +++ + A +++F+DL + F I E L +W+++V KNYRNV YHNW HAFNV MM IL ++ +IE L LI+GCLCHDLDHRGTNN+FQIK SPLAQLY + +T+E HHF+ +MI+N+ GN I +L++D Y ++ +++ +IL+TDL+ +FK R F V W + E R LLR MT CDL+A TK W + ++ A LV EFF+QGD+EK I P +M+R +DELP +Q+ +I S+C P++ + + + + + + +N HW +L
Sbjct: 517 FSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHE-ADKGSFSRVFDFEANDLSEEEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFKFDDIHFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLY-STSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEPLVEGVRDNRGHWIDL 1059 HSP 2 Score: 60.8474 bits (146), Expect = 3.316e-9 Identity = 35/89 (39.33%), Postives = 49/89 (55.06%), Query Frame = 3
Query: 711 ESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD-FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALE 974
E F C+ +D L +++C PI DSS VIG AQVINK+ + FS+ DE + + FC +G+ N +LYE R QV L+
Sbjct: 465 ERFNCE----IDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLD 549
BLAST of Phosphodiesterase vs. Ensembl Fly
Match: Pde11 (gene:FBgn0085370 transcript:FBtr0303162) HSP 1 Score: 384.8 bits (987), Expect = 2.786e-119 Identity = 207/545 (37.98%), Postives = 315/545 (57.80%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPS---NFGFHCTLNTENKFSLTSEKIGSR-----KIAKMVCINGESFKCKS-------EEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKL-ERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
+ + Q C GL NA L+E E RN+VLL+ ++EEQ+++E + + + M+ +I+C+ V + L+ A+K S F F +E + + + SR I V GE+ + + +DE S++C I +S +IG Q+INK E DF+KNDE+ +EA IFC +GI N +YE + A+ V LE LSYH +A++ E H + +PS +L KF+D +++ + A +++F+DL + F I E L +W+++V KNYRNV YHNW HAFNV MM IL ++ +IE L LI+GCLCHDLDHRGTNN+FQIK SPLAQLY + +T+E HHF+ +MI+N+ GN I +L++D Y ++ +++ +IL+TDL+ +FK R F V W + E R LLR MT CDL+A TK W + ++ A LV EFF+QGD+EK I P +M+R +DELP +Q+ +I S+C P++ + + + + + + +N HW +L
Sbjct: 561 FSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLDLARMIFEEQSTIEHMVFRILTHMQSLIQCQRVQILLVHE-ADKGSFSRVFDFEANDLSEEEATSRTSPYESRFPINIGITGHVATTGETVNVPNAYEDDRFDASVDENSCFKHRSILCMAIKNSLGQIIGVIQLINKFNELDFTKNDENFVEAFAIFCGMGIHNTHMYEKAIVAMAKQSVTLEVLSYHASATMDEAHRLRRLRVPSAVHFRLHDFKFDDIHFEDDDTLKACLRMFLDLDFVERFHIDYEVLCRWLLSVKKNYRNVTYHNWRHAFNVAQMMFAILTTTQWWKIFGEIECLALIIGCLCHDLDHRGTNNSFQIKASSPLAQLY-STSTMEHHHFDQCLMILNSPGNQILANLSSDDYCRVIRVLEDAILSTDLAVYFKKRGPFLESVSQPTSYWVAEEPRALLRAMSMTVCDLSAITKPWEIEKRVADLVSSEFFEQGDMEKQELNITPIDIMNREKEDELPMMQVNFIDSICLPIYEAFATLSDKLEPLVEGVRDNRGHWIDL 1103 HSP 2 Score: 61.2326 bits (147), Expect = 3.238e-9 Identity = 35/89 (39.33%), Postives = 49/89 (55.06%), Query Frame = 3
Query: 711 ESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD-FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALE 974
E F C+ +D L +++C PI DSS VIG AQVINK+ + FS+ DE + + FC +G+ N +LYE R QV L+
Sbjct: 509 ERFNCE----IDSLTGYRTKALLCMPIKDSSGDVIGVAQVINKMNGECFSEIDEKVFSSYLQFCGIGLRNAQLYEKSQLEIKRNQVLLD 593
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 425.631 bits (1093), Expect = 3.561e-137 Identity = 221/550 (40.18%), Postives = 326/550 (59.27%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKF------SLTSEKIGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
L + C + NA LF E+ R++ LLE +++L+EEQ LEK ++K +H+ + ++KCE +V LL+ F C+ + EN F S S+ + + IA++V G ++++ + + + D+ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S TEV IP + F+DFSL + MV A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV M +L + L ++E L LIVGC+CHDLDHRGTNN FQ KT S L+ LYG ATLE HHFN VMI+ ++G+NIF +L++ +Y LM ++KQSILATDL+ +F+ R FF V +W E R++ R LMT+CDL A TK W ++ K A LV EFF+QGD E++ K+ P + DR+ +DELP +Q++WI +C PL+ ++ + Q M D + N W EL
Sbjct: 309 LQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADMENSFKDSMDKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMVTAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSMLTTAGFQETLTEMETLALIVGCICHDLDHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFSNLSSHEYGELMQLLKQSILATDLTLYFQNRNSFFELVNKGEYNWNVKEHREMCRSMLMTACDLGAVTKPWEISHKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETFAKLNPKLQPMMDLIKANRAKWEEL 858 HSP 2 Score: 54.6842 bits (130), Expect = 3.278e-7 Identity = 27/85 (31.76%), Postives = 48/85 (56.47%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C PI +S VIG AQ INK F+++DE +++ FC + I+N +L+ K R++ LE ++
Sbjct: 260 DEIDKLTGYKTKSLLCMPIHNSDGEVIGVAQAINKSPNGALFTQDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVN 344
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde11al (phosphodiesterase 11a, like [Source:ZFIN;Acc:ZDB-GENE-031118-106]) HSP 1 Score: 415.231 bits (1066), Expect = 7.061e-133 Identity = 212/547 (38.76%), Postives = 325/547 (59.41%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLD----VCAEKPSNFGFHCTLNTENKFSLTSEKIG------SRKIAKMVCINGESFK----CKS---EEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD-FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
L + C + NA LF E+ R++ LLE +++L+EEQ LEK ++K + + +++CE +V LL+ + F L + ++ ++ EK+ + IA++V G C+ + + D+ I S++C PIW+ ++ +IG AQ++N+L+R F+ D+ + EA IFC +GI N +Y + K+ A+ VAL+ LSYH T S EV + IP S + FNDFSL N+ M+ A++++F++L ++ F I E L +W++TV KNYR VAYHNW HAFNV M ++ + +VL + E L L+VGC CHDLDHRGTNN FQ K+ S LA LYG ATLE HHFN VMI+ ++G+NIF +L + +Y +M ++KQ+IL+TDL+ +FK R FF V + W E R + R LMT+CDL A T+ W ++++ A LV EFF+QGD E++ K+ P + DR+ +DELP +Q++WI +C+PL+ L ++++ Q M D + N W EL
Sbjct: 315 LQMYLPFCGISISNAKLFSESRKEYERSRALLEVVNDLFEEQTDLEKIVRKIMQRALTLLQCERCSVLLLEDIHSPVVKFSQTFELMSPLCSVDR-DISMEKVSCSDWLINNSIAELVASTGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLSYHATCSKAEVDRLKAAKIPLSSELGIDEFHFNDFSLDNDAMITASLRMFLELGVVQKFKIDYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFIMITTAAFQEVLTETETLALMVGCFCHDLDHRGTNNAFQAKSGSALALLYGTSATLEHHHFNHAVMILQSEGHNIFANLCSKEYCNMMQLLKQAILSTDLTLYFKKRTTFFDCVLSGQFSWSDEEHRDMFRSMLMTACDLGAVTRPWEISKQVAELVTSEFFEQGDRERSELKLTPAAIFDRNRKDELPVLQLEWIDGICKPLYEALVKLNRKLQPMVDGIDANRKKWEEL 860 HSP 2 Score: 50.0618 bits (118), Expect = 9.256e-6 Identity = 25/85 (29.41%), Postives = 47/85 (55.29%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C I +S VIG Q INK F+++DE +++ FC + I+N +L+ + K R++ LE ++
Sbjct: 266 DEIDKLTGYKTQSILCMAIRNSDGEVIGVVQAINKNPSGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYERSRALLEVVN 350
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 397.127 bits (1019), Expect = 1.752e-126 Identity = 212/543 (39.04%), Postives = 314/543 (57.83%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKF------SLTSEKIGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
C + NA LF E+ R++ LLE +++L+EEQ LEK ++K +H+ + ++KCE +V LL+ F C+ + EN F S S+ + + IA++V G ++++ + + + D+ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S TEV IP + F+DFSL + MV A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV M +L + L ++E L LIVGC+CHDLDHRGTNN FQ KT S L+ LYG ATLE HHFN VMI+ ++G+NIF +L++ +Y LM ++KQSILATDL+ +F++ LMT+CDL A TK W ++ K A LV EFF+QGD E++ K+ P + DR+ +DELP +Q++WI +C PL+ ++ + Q M D + N W EL
Sbjct: 313 CGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADMENSFKDSMDKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMVTAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSMLTTAGFQETLTEMETLALIVGCICHDLDHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFSNLSSHEYGELMQLLKQSILATDLTLYFQS--------------------------MLMTACDLGAVTKPWEISHKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETFAKLNPKLQPMMDLIKANRAKWEEL 829
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde5ab (phosphodiesterase 5A, cGMP-specific, b [Source:ZFIN;Acc:ZDB-GENE-060824-4]) HSP 1 Score: 353.599 bits (906), Expect = 6.459e-110 Identity = 201/556 (36.15%), Postives = 315/556 (56.65%), Query Frame = 3
Query: 408 LYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFG--FH----------------CTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDS-SNHVIGAAQVINKLE------RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVH--HIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS*LL 1991
L+NA L+ET E RN+VLL+ ++EEQ SLE ++K+V + ++ +E VF+ D E + F FH C +N N K + + F SE+ + I S++C PI + + VIG Q++NK++ + F++NDE +EA +FC +GI N ++YE + ++ A+ +V LE LSYH +A+ E + IPS + +L + F+DF L++ E AT+++F+DLK++ F IK ++L +W+++V KNYR NV YHNW HAFN M +L V L D+E L L++ L HDLDHRG NN++ ++D PLAQLY + +T+E HHF+ +MI+N+ GN I L+ D+Y + +I+++ILATDL+ + K R +FF +N +W R LLR LMT+CD++A TK WPV +K A LV EFF+QGD E+ I+P +M+R QD++P +Q+ +I ++C L+ LT + + + + +N +W L + E + LL
Sbjct: 313 LHNAQLYETSQLENRRNQVLLDLASLIFEEQQSLEVLLRKTVATILSFMQAQECTVFISD--RETANTFASVFHMEYEEIAGSTDFPNRECDVNKINYMYAQYVKNTMETLNITDTTKDQLFSWTSEDP--QSTNCQIKSLLCTPIRNGKKDKVIGVCQLVNKMDEASGEVKAFNRNDEQFLEAFAVFCGLGIQNTQMYEAVERAMAKQEVTLEVLSYHASAAEEETRALQVTAATIPSAQSLRLMDYSFSDFDLTDAETTQATIRMFVDLKLVQNFQIKYKSLCQWILSVKKNYRKNVVYHNWRHAFNTSQCMFAVLKSGRVQNNLSDLETLALMIATLSHDLDHRGVNNSYIKRSDHPLAQLYCH-STMEHHHFDQCLMILNSPGNQILSGLSLDEYKATLKMIEKAILATDLAVYMKKRTEFFELAKNSQFEWEDDCHRDLLRSMLMTACDISAITKPWPVQKKIAELVATEFFEQGDKERRELNIEPIDLMNREKQDKIPSMQVSFIDAICTQLYEALTGISEFCSPLLEGCRKNRQNWKILAEQGEEAALL 863
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Match: pde5ab (phosphodiesterase 5A, cGMP-specific, b [Source:ZFIN;Acc:ZDB-GENE-060824-4]) HSP 1 Score: 347.436 bits (890), Expect = 1.655e-107 Identity = 201/559 (35.96%), Postives = 315/559 (56.35%), Query Frame = 3
Query: 408 LYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFG--FH----------------CTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDS-SNHVIGAAQVINKLE------RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHI---MEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQE--TLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS*LL 1991
L+NA L+ET E RN+VLL+ ++EEQ SLE ++K+V + ++ +E VF+ D E + F FH C +N N K + + F SE+ + I S++C PI + + VIG Q++NK++ + F++NDE +EA +FC +GI N ++YE + ++ A+ +V LE LSYH +A+ E + IPS + +L + F+DF L++ E AT+++F+DLK++ F IK + +L +W+++V KNYR NV YHNW HAFN M +L V L D+E L L++ L HDLDHRG NN++ ++D PLAQLY + +T+E HHF+ +MI+N+ GN I L+ D+Y + +I+++ILATDL+ + K R +FF +N +W R LLR LMT+CD++A TK WPV +K A LV EFF+QGD E+ I+P +M+R QD++P +Q+ +I ++C L+ LT + + + + +N +W L + E + LL
Sbjct: 313 LHNAQLYETSQLENRRNQVLLDLASLIFEEQQSLEVLLRKTVATILSFMQAQECTVFISD--RETANTFASVFHMEYEEIAGSTDFPNRECDVNKINYMYAQYVKNTMETLNITDTTKDQLFSWTSEDP--QSTNCQIKSLLCTPIRNGKKDKVIGVCQLVNKMDEASGEVKAFNRNDEQFLEAFAVFCGLGIQNTQMYEAVERAMAKQEVTLEVLSYHASAAEEETRALQVTAAATIPSAQSLRLMDYSFSDFDLTDAETTQATIRMFVDLKLVQNFQIKYKVPSLCQWILSVKKNYRKNVVYHNWRHAFNTSQCMFAVLKSGRVQNNLSDLETLALMIATLSHDLDHRGVNNSYIKRSDHPLAQLYCH-STMEHHHFDQCLMILNSPGNQILSGLSLDEYKATLKMIEKAILATDLAVYMKKRTEFFELAKNSQFEWEDDCHRDLLRSMLMTACDISAITKPWPVQKKIAELVATEFFEQGDKERRELNIEPIDLMNREKQDKIPSMQVSFIDAICTQLYEALTGISEFCSPLLEGCRKNRQNWKILAEQGEEAALL 866
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: ENSXETT00000053056.1 (phosphodiesterase 11A [Source:NCBI gene;Acc:100379882]) HSP 1 Score: 436.417 bits (1121), Expect = 4.701e-141 Identity = 223/546 (40.84%), Postives = 331/546 (60.62%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
C + NA LF E+ R++ LLE +++L+EEQ LEK +KK +H+ + ++KCE +V LL+ F C+ +TEN F + EK + + IA++V G ++++ + + + D+ I S++C PIW+SS+ +IG AQV+N+++ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S EV IP S + F+DF L + M+ A +++F++L ++ F I ETL +W++T+ KNYR V YHNW HAFNV +M +L +VL D E L LIVGCLCHDLDHRGTNN FQ K+ S L+QLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATD++ HF+ R +FF V + +W R + R LMT+CDL AATK W ++++ A LV EFF+QGD E+ K+ P + DR+ +DELP +Q++WI ++C PL+ L ++ + + M D + N W EL K
Sbjct: 321 CGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKVVKKIMHRAQNLLKCERCSVLLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSVEKSSYSDWLVNNSIAELVASTGLPVNISDAYQDPRFDVEADQFSGFHIRSVLCVPIWNSSHQIIGVAQVLNRIDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELSIADIHFDDFCLDVDAMISAALRMFMELGMVQKFKIDYETLCRWLLTIRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEVLSDTETLALIVGCLCHDLDHRGTNNAFQAKSGSALSQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSQEYSDLMQLLKQSILATDITLHFERRNEFFELVNKGDYNWNVKSHRVIFRSMLMTACDLGAATKPWEISRQVAELVTSEFFEQGDRERLELKMTPSAIFDRNRKDELPRLQLEWIDNICFPLYESLVKINGKLKPMLDSVTTNRGKWEELHRK 866 HSP 2 Score: 53.5286 bits (127), Expect = 1.061e-6 Identity = 27/85 (31.76%), Postives = 46/85 (54.12%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C PI S +IG AQ INK F ++DE +M+ FC + I+N +L+ K R++ LE ++
Sbjct: 265 DEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKTPGGAPFIEDDEKVMQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVN 349
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: pde5a (phosphodiesterase 5A [Source:NCBI gene;Acc:780273]) HSP 1 Score: 342.813 bits (878), Expect = 3.852e-106 Identity = 206/568 (36.27%), Postives = 312/568 (54.93%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFG--FHCTLNT--ENKFSLTSEKIGSRK---IAKMVCINGESFK----CKSEEKLDELKEIGI---------SSMICKPIWDSS-NHVIGAAQVINKLERD------FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL------------KSKPEI 1979
C L+NA L+ET E RN+VLL+ ++EEQ SLE +KK + ++ + +F++D + P F FH + E+ ++ E S+ A+ V E+ CK + + I S++C PI ++ N VIG Q++NK++ + F+KNDE +EA IFC +GI N +++E + ++ A+ V LE LSYH +A+ E + +PS + +L F+DF LS+ E LAT ++F DL ++ F +K ETL +W+++V KNYR NVAYHNW HAFN M L + L D+EIL L++ L HDLDHRG NN+F +++ PLAQLY + + +E HHF+ +MI+N+ GN I L+ Y T++ +IKQ+ILATDL+ + K R FF V + W Q++L LMT+CDL+A TK WPV Q+ A LV EF+ QGD E+ I+P +M+R +D++P +Q+ +I +VC L+ LT + + + D N W L KS+PE+
Sbjct: 253 CGIVLHNAQLYETSLLENRRNQVLLDLATLIFEEQQSLEVILKKIAATILSFMQAQRCTIFIVD--EDSPDTFSSVFHMESDELEESADAVKREYDVSKMNYMYAQYVANTMEAINIPDICKDTRFPWTVNKKNIFFYFNFKHIQSLLCSPIKNAKKNKVIGVCQLVNKVDENSGKIKAFNKNDEQFLEAFAIFCGLGIQNTQMFEVVERAMAKQMVTLEILSYHASAAEEETMELQGAIVPSAQSLKLTEFYFSDFELSDMETTLATSRMFTDLNLVQTFQMKYETLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALRTGKIQGKLNDLEILALMIATLSHDLDHRGVNNSFIQRSEHPLAQLYCH-SIMENHHFDQCLMILNSQGNQILSGLSVQDYKTVLKMIKQAILATDLALYIKRRSDFFELVNKKKFKWDDPSQKELFLAMLMTACDLSAITKPWPVQQRIAELVASEFYDQGDKERRELNIEPIDLMNREKKDKIPSMQVGFIDAVCLELYEALTQISESCYPLLDGCQRNRQMWQILAEQQEKNLVNGAKSQPEV 817
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: pde5a (phosphodiesterase 5A [Source:NCBI gene;Acc:780273]) HSP 1 Score: 341.658 bits (875), Expect = 1.795e-105 Identity = 203/553 (36.71%), Postives = 308/553 (55.70%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAK-MVCINGESFKCKSEEKLDELKEIG-ISSMICKPIWDSS-NHVIGAAQVINKLERD------FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKP---IPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL------------KSKPEI 1979
C L+NA L+ET E RN+VLL+ ++EEQ SLE +KK + ++ + +F++D + P + T + + ++ +A M IN CK + + K I S++C PI ++ N VIG Q++NK++ + F+KNDE +EA IFC +GI N +++E + ++ A+ V LE LSYH +A+ E + +PS + +L F+DF LS+ E LAT ++F DL ++ F +K ETL +W+++V KNYR NVAYHNW HAFN M L + L D+EIL L++ L HDLDHRG NN+F +++ PLAQLY + + +E HHF+ +MI+N+ GN I L+ Y T++ +IKQ+ILATDL+ + K R FF V + W Q++L LMT+CDL+A TK WPV Q+ A LV EF+ QGD E+ I+P +M+R +D++P +Q+ +I +VC L+ LT + + + D N W L KS+PE+
Sbjct: 299 CGIVLHNAQLYETSLLENRRNQVLLDLATLIFEEQQSLEVILKKIAATILSFMQAQRCTIFIVD--EDSPVWDLLYRMFGTWDFLDYKMNYMYAQYVANTMEAINIPDI-CK-DTRFPWTKNFKHIQSLLCSPIKNAKKNKVIGVCQLVNKVDENSGKIKAFNKNDEQFLEAFAIFCGLGIQNTQMFEVVERAMAKQMVTLEILSYHASAAEEETMELQVTAGAIVPSAQSLKLTEFYFSDFELSDMETTLATSRMFTDLNLVQTFQMKYETLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALRTGKIQGKLNDLEILALMIATLSHDLDHRGVNNSFIQRSEHPLAQLYCH-SIMENHHFDQCLMILNSQGNQILSGLSVQDYKTVLKMIKQAILATDLALYIKRRSDFFELVNKKKFKWDDPSQKELFLAMLMTACDLSAITKPWPVQQRIAELVASEFYDQGDKERRELNIEPIDLMNREKKDKIPSMQVGFIDAVCLELYEALTQISESCYPLLDGCQRNRQMWQILAEQQEKNLVNGAKSQPEV 846
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: pde5a (phosphodiesterase 5A [Source:NCBI gene;Acc:780273]) HSP 1 Score: 340.887 bits (873), Expect = 1.910e-105 Identity = 205/554 (37.00%), Postives = 309/554 (55.78%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFG--FHCTLNT--ENKFSLTSEKIGSRK---IAKMVCINGESFK----CKSEE----KLDELKEIG-ISSMICKPIWDSS-NHVIGAAQVINKLERD------FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKP---IPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPE 1976
C L+NA L+ET E RN+VLL+ ++EEQ SLE +KK + ++ + +F++D + P F FH + E+ ++ E S+ A+ V E+ CK +E K I S++C PI ++ N VIG Q++NK++ + F+KNDE +EA IFC +GI N +++E + ++ A+ V LE LSYH +A+ E + +PS + +L F+DF LS+ E LAT ++F DL ++ F +K ETL +W+++V KNYR NVAYHNW HAFN M L + L D+EIL L++ L HDLDHRG NN+F +++ PLAQLY + + +E HHF+ +MI+N+ GN I L+ Y T++ +IKQ+ILATDL+ + K R FF V + W Q++L LMT+CDL+A TK WPV Q+ A LV EF+ QGD E+ I+P +M+R +D++P +Q+ +I +VC L+ LT + + + D N W L + E
Sbjct: 253 CGIVLHNAQLYETSLLENRRNQVLLDLATLIFEEQQSLEVILKKIAATILSFMQAQRCTIFIVD--EDSPDTFSSVFHMESDELEESADAVKREYDVSKMNYMYAQYVANTMEAINIPDICKDTRFPWTNGNEEKNFKHIQSLLCSPIKNAKKNKVIGVCQLVNKVDENSGKIKAFNKNDEQFLEAFAIFCGLGIQNTQMFEVVERAMAKQMVTLEILSYHASAAEEETMELQVTAGAIVPSAQSLKLTEFYFSDFELSDMETTLATSRMFTDLNLVQTFQMKYETLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALRTGKIQGKLNDLEILALMIATLSHDLDHRGVNNSFIQRSEHPLAQLYCH-SIMENHHFDQCLMILNSQGNQILSGLSVQDYKTVLKMIKQAILATDLALYIKRRSDFFELVNKKKFKWDDPSQKELFLAMLMTACDLSAITKPWPVQQRIAELVASEFYDQGDKERRELNIEPIDLMNREKKDKIPSMQVGFIDAVCLELYEALTQISESCYPLLDGCQRNRQMWQILAEQQE 803
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Match: pde5a (phosphodiesterase 5A [Source:NCBI gene;Acc:780273]) HSP 1 Score: 340.887 bits (873), Expect = 2.330e-105 Identity = 208/567 (36.68%), Postives = 313/567 (55.20%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFG--FHCTLNT--ENKFSLTSEKIGSRK---IAKMVCINGESFK----CKSEE----KLDELKEIG-ISSMICKPIWDSS-NHVIGAAQVINKLERD------FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKP---IPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL------------KSKPEI 1979
C L+NA L+ET E RN+VLL+ ++EEQ SLE +KK + ++ + +F++D + P F FH + E+ ++ E S+ A+ V E+ CK +E K I S++C PI ++ N VIG Q++NK++ + F+KNDE +EA IFC +GI N +++E + ++ A+ V LE LSYH +A+ E + +PS + +L F+DF LS+ E LAT ++F DL ++ F +K ETL +W+++V KNYR NVAYHNW HAFN M L + L D+EIL L++ L HDLDHRG NN+F +++ PLAQLY + + +E HHF+ +MI+N+ GN I L+ Y T++ +IKQ+ILATDL+ + K R FF V + W Q++L LMT+CDL+A TK WPV Q+ A LV EF+ QGD E+ I+P +M+R +D++P +Q+ +I +VC L+ LT + + + D N W L KS+PE+
Sbjct: 259 CGIVLHNAQLYETSLLENRRNQVLLDLATLIFEEQQSLEVILKKIAATILSFMQAQRCTIFIVD--EDSPDTFSSVFHMESDELEESADAVKREYDVSKMNYMYAQYVANTMEAINIPDICKDTRFPWTNGNEEKNFKHIQSLLCSPIKNAKKNKVIGVCQLVNKVDENSGKIKAFNKNDEQFLEAFAIFCGLGIQNTQMFEVVERAMAKQMVTLEILSYHASAAEEETMELQVTAGAIVPSAQSLKLTEFYFSDFELSDMETTLATSRMFTDLNLVQTFQMKYETLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALRTGKIQGKLNDLEILALMIATLSHDLDHRGVNNSFIQRSEHPLAQLYCH-SIMENHHFDQCLMILNSQGNQILSGLSVQDYKTVLKMIKQAILATDLALYIKRRSDFFELVNKKKFKWDDPSQKELFLAMLMTACDLSAITKPWPVQQRIAELVASEFYDQGDKERRELNIEPIDLMNREKKDKIPSMQVGFIDAVCLELYEALTQISESCYPLLDGCQRNRQMWQILAEQQEKNLVNGAKSQPEV 822
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde11a (phosphodiesterase 11A [Source:MGI Symbol;Acc:MGI:3036251]) HSP 1 Score: 447.588 bits (1150), Expect = 4.775e-145 Identity = 226/546 (41.39%), Postives = 332/546 (60.81%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCINGESFKC-------KSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
C + NA LF E+ R++ LLE +++L+EEQ LEK +KK +H+ + ++KCE +V LL+ F C+ + EN F + EK + + IA++V G + + + D++ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S EV IP S + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV +M +L ++L ++EIL +IVGCLCHDLDHRGTNN FQ K+DS LAQLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R +FF V + DW R + R LMT+CDL A TK W ++++ A LV EFF+QGD E++ K+ P + DR+ +DELP +Q++WI S+C PL++ L V+ + + M D + N W EL K
Sbjct: 366 CGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAANRRKWEELHQK 911 HSP 2 Score: 56.9954 bits (136), Expect = 7.123e-8 Identity = 27/84 (32.14%), Postives = 48/84 (57.14%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEAL 980
+++D+L S++C PI +S +IG AQ INK+ F+++DE +M+ FC + I+N +L+ K R++ LE +
Sbjct: 310 DEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVV 393
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde11a (phosphodiesterase 11A [Source:MGI Symbol;Acc:MGI:3036251]) HSP 1 Score: 331.257 bits (848), Expect = 2.940e-106 Identity = 180/464 (38.79%), Postives = 263/464 (56.68%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCINGESFKC-------KSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQK 1724
C + NA LF E+ R++ LLE +++L+EEQ LEK +KK +H+ + ++KCE +V LL+ F C+ + EN F + EK + + IA++V G + + + D++ I S++C PIW+S++ +IG AQV+N+L+ + F D+ RL+E LSYH T S EV IP S + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV +M +L ++L ++EIL +IVGCLCHDLDHRGTNN FQ K+DS LAQLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R +FF V + DW R + R LMT+CDL A TK W ++++
Sbjct: 5 CGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQ-----------------RLFE--------------VLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQ 437
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde5a (phosphodiesterase 5A, cGMP-specific [Source:MGI Symbol;Acc:MGI:2651499]) HSP 1 Score: 342.813 bits (878), Expect = 3.649e-106 Identity = 199/555 (35.86%), Postives = 309/555 (55.68%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFG--FHCTLNTENKFS--LTSEKIGSR---KIAKMVCINGESFKCK----------SEEKLDELKEIGISSMICKPIWDSS-NHVIGAAQVINKLERD------FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTAS---LTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPE 1976
C L+NA L+ET E RN+VLL+ ++EEQ SLE +KK + ++ ++ +F++D + P +F FH K S LT E+ ++ A+ V E + E + + I S++C PI + N VIG Q++NK+E + F++NDE +EA IFC +GI N ++YE + ++ A+ V LE LSYH +A+ E+ + +PS T ++ F+DF LS+ E L T+++F DL ++ F +K E L +W+++V KNYR NVAYHNW HAFN M L + L D+E L L++ L HDLDHRG NN++ +++ PLAQLY + + +E HHF+ +MI+N+ GN I L+ D+Y T + IIKQ+ILATDL+ + K R +FF + + Q++L LMT+CDL+A TK WP+ Q+ A LV EFF QGD E+ ++P +M+R ++++P +Q+ +I ++C L+ LT V + + D +N W L + E
Sbjct: 268 CGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVD--EDCPDSFSRVFHMECEEVGKPSDPLTREQDANKINYMYAQYVKNTMEPLNIPDVTKDKRFPWTNENMGHVNTPCIGSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKIKAFNQNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQALSAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCH-SIMEHHHFDQCLMILNSPGNQILSGLSIDEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFSFEDPLQKELFLAMLMTACDLSAITKPWPIQQRIAELVAAEFFDQGDRERKELNMEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCLPLLDGCRKNRQKWQALAEQQE 819
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde5a (phosphodiesterase 5A, cGMP-specific [Source:MGI Symbol;Acc:MGI:2651499]) HSP 1 Score: 342.428 bits (877), Expect = 1.077e-105 Identity = 199/555 (35.86%), Postives = 309/555 (55.68%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFG--FHCTLNTENKFS--LTSEKIGSR---KIAKMVCINGESFKCK----------SEEKLDELKEIGISSMICKPIWDSS-NHVIGAAQVINKLERD------FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTAS---LTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPE 1976
C L+NA L+ET E RN+VLL+ ++EEQ SLE +KK + ++ ++ +F++D + P +F FH K S LT E+ ++ A+ V E + E + + I S++C PI + N VIG Q++NK+E + F++NDE +EA IFC +GI N ++YE + ++ A+ V LE LSYH +A+ E+ + +PS T ++ F+DF LS+ E L T+++F DL ++ F +K E L +W+++V KNYR NVAYHNW HAFN M L + L D+E L L++ L HDLDHRG NN++ +++ PLAQLY + + +E HHF+ +MI+N+ GN I L+ D+Y T + IIKQ+ILATDL+ + K R +FF + + Q++L LMT+CDL+A TK WP+ Q+ A LV EFF QGD E+ ++P +M+R ++++P +Q+ +I ++C L+ LT V + + D +N W L + E
Sbjct: 300 CGIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIFIVD--EDCPDSFSRVFHMECEEVGKPSDPLTREQDANKINYMYAQYVKNTMEPLNIPDVTKDKRFPWTNENMGHVNTPCIGSLLCTPIKNGKKNKVIGVCQLVNKMEENTGKIKAFNQNDEQFLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQALSAAVVPSAQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCRWILSVKKNYRKNVAYHNWRHAFNTAQCMFAALKAGKIQNKLTDLETLALLIAALSHDLDHRGVNNSYIQRSEHPLAQLYCH-SIMEHHHFDQCLMILNSPGNQILSGLSIDEYKTTLKIIKQAILATDLALYIKRRGEFFELIRKNQFSFEDPLQKELFLAMLMTACDLSAITKPWPIQQRIAELVAAEFFDQGDRERKELNMEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCLPLLDGCRKNRQKWQALAEQQE 851
BLAST of Phosphodiesterase vs. Ensembl Mouse
Match: Pde6c (phosphodiesterase 6C, cGMP specific, cone, alpha prime [Source:MGI Symbol;Acc:MGI:105956]) HSP 1 Score: 257.684 bits (657), Expect = 2.733e-74 Identity = 163/594 (27.44%), Postives = 289/594 (48.65%), Query Frame = 3
Query: 435 YSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEK----------------------------------------------PSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIME-----------------------KPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTR----------EKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPE 1976
YS E R+++L+ S ++++EE +E+ K+++ ++ + C+ ++ LLD+ EK PS H TL + L + + I M+ + + + +DE + I +++ PI + ++G A N+ + + F ++DE I E +T F + N YE + K +R +A E + T A+ E+ I++ + +P T+ L F+DF ++ E+V ++LF+++ ++ F + E L +W+ TV K YR V YHNW H FNV M +L + + D+E ++ CHD+DHRGTNN +Q+K+ SPLA+L+G + LE+HH + ++ ++ NIF++L Q+ T++ + + +I+ATDL+ +FK R E+ SE E +++++ +MT+CDL+A TK W V + A+LV EF++QGD+E+ + + QP MMDRS +DELP++Q+ +I VC +++ + + M + L N V W L + E
Sbjct: 233 YSVESRRSQILMWSANKVFEELTDVERQFHKALYTIRTYLNCDRYSIGLLDMTKEKEFYDEWPIKLGEVEPYKGPKTPDGREIIFYKIIDYILHGKEEINVIPSPPADHWTLVS----GLPTYVAENGFICNMLNAPADEYFTFQKGPVDETGWV-IKNVLSLPIVNKKEDIVGVATFYNRKDGKPFDEHDEHITETLTQFLGWSLLNTDTYERVNKLESRKDIAQEMVMNLTKATPDEISSILKFKEKLNVEVIEECEERQLLAILKEDLPDPRTADLYEFCFSDFPITEHELVKCGLRLFLEINVVEKFKVPVEVLTRWMYTVRKGYRPVTYHNWRHGFNVGQTMFTLLMTGRLKKYYTDLEAFAMLAAAFCHDIDHRGTNNLYQMKSTSPLARLHGT-SILERHHLEYSKTLLQDESLNIFQNLNKRQFETVIHLFEVAIIATDLALYFKKRTMFQKIVDTCEQMQSEEETIKYVTSDPTKKEVIMAMMMTACDLSAITKPWEVQSQVALLVANEFWEQGDLERTVLQQQPIPMMDRSKKDELPKLQVGFIDFVCTFVYKEFSRFHGEITPMLNGLQNNRVEWKSLAEEYE 820
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|P0C1Q2|PDE11_MOUSE (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Mus musculus OX=10090 GN=Pde11a PE=1 SV=1) HSP 1 Score: 447.588 bits (1150), Expect = 3.340e-144 Identity = 226/546 (41.39%), Postives = 332/546 (60.81%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCINGESFKC-------KSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
C + NA LF E+ R++ LLE +++L+EEQ LEK +KK +H+ + ++KCE +V LL+ F C+ + EN F + EK + + IA++V G + + + D++ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S EV IP S + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV +M +L ++L ++EIL +IVGCLCHDLDHRGTNN FQ K+DS LAQLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R +FF V + DW R + R LMT+CDL A TK W ++++ A LV EFF+QGD E++ K+ P + DR+ +DELP +Q++WI S+C PL++ L V+ + + M D + N W EL K
Sbjct: 366 CGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAANRRKWEELHQK 911 HSP 2 Score: 56.9954 bits (136), Expect = 4.982e-7 Identity = 27/84 (32.14%), Postives = 48/84 (57.14%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEAL 980
+++D+L S++C PI +S +IG AQ INK+ F+++DE +M+ FC + I+N +L+ K R++ LE +
Sbjct: 310 DEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVV 393
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q8VID6|PDE11_RAT (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Rattus norvegicus OX=10116 GN=Pde11a PE=1 SV=1) HSP 1 Score: 446.047 bits (1146), Expect = 1.343e-143 Identity = 226/546 (41.39%), Postives = 331/546 (60.62%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCINGESFKC-------KSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
C + NA LF E+ R++ LLE +++L+EEQ LEK +KK +H+ + ++KCE +V LL+ F C+ + EN F + EK + + IA++V G + + + D++ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S EV IP S + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV +M +L ++L ++EIL +IVGCLCHDLDHRGTNN FQ K+DS LAQLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R +FF V DW R + R LMT+CDL A TK W ++++ A LV EFF+QGD E++ K+ P + DR+ +DELP +Q++WI S+C PL++ L V+ + + M D + N W EL K
Sbjct: 366 CGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGAYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAANRRKWEELHQK 911 HSP 2 Score: 56.9954 bits (136), Expect = 5.028e-7 Identity = 27/85 (31.76%), Postives = 49/85 (57.65%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C PI +S +IG AQ INK+ F+++DE +M+ FC + I+N +L+ K R++ LE ++
Sbjct: 310 DEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVN 394
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q9HCR9|PDE11_HUMAN (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Homo sapiens OX=9606 GN=PDE11A PE=1 SV=2) HSP 1 Score: 439.499 bits (1129), Expect = 3.911e-141 Identity = 225/546 (41.21%), Postives = 332/546 (60.81%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
C + NA LF E+ R++ LLE +++L+EEQ LEK +KK +H+ + ++KCE +V LL+ F C+ + EN F + EK + + IA++V G ++++ + + + D++ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S EV IP S + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV +M +L +L ++EIL +IVGCLCHDLDHRGTNN FQ K+ S LAQLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R +FF V DW R + R LMT+CDL A TK W ++++ A LV EFF+QGD E+ K+ P + DR+ +DELP +Q++WI S+C PL++ L V+ + + M D + N W EL K
Sbjct: 366 CGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSVATNRSKWEELHQK 911 HSP 2 Score: 56.9954 bits (136), Expect = 5.811e-7 Identity = 27/85 (31.76%), Postives = 48/85 (56.47%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C PI S +IG AQ INK+ F+++DE +M+ FC + I+N +L+ K R++ LE ++
Sbjct: 310 DEIDKLTGYKTKSLLCMPIRSSDGEIIGVAQAINKIPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVN 394
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|Q1KKS3|PDE11_TAKRU (Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A OS=Takifugu rubripes OX=31033 GN=pde11a PE=3 SV=1) HSP 1 Score: 432.18 bits (1110), Expect = 1.424e-138 Identity = 224/553 (40.51%), Postives = 331/553 (59.86%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
L + C + NA LF E+ R++ LLE +++L+EEQ LEK ++K +H+ + ++KCE +V LL+ F C+ + E+ F + EK + + IA++V G ++++ + + + D+ + I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S TEV IP + F+DFSL + M+ A +++FI+L ++ F I ETL +W++TV KNYR V YHNW HAFNV M +L + L D+EIL LIVGC+CHDLDHRGTNN FQ KT S L+ LYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R FF V +W R + R +MT+CDL A TK W +++K A LV EFF+QGD E++ K+ P + DR+ +DELP +Q++WI +C PL+ L ++ + Q M D + N V W EL K
Sbjct: 313 LQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADAESSFKDSMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSDFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMFIELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFAMLTTAGFQETLTDVEILALIVGCVCHDLDHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFCNLSSTEYSDLMQLLKQSILATDLTLYFENRNSFFELVSIGEYNWNVKTHRDMCRSMMMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETLVKLNPKLQPMVDMINANRVKWEELDKK 865 HSP 2 Score: 53.9138 bits (128), Expect = 4.633e-6 Identity = 26/85 (30.59%), Postives = 48/85 (56.47%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C PI +S +IG AQ INK F+++DE +++ FC + I+N +L+ K R++ LE ++
Sbjct: 264 DEIDKLTGYKTKSLLCMPIQNSDGEIIGVAQAINKSSSGELFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVN 348
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Match: sp|B4LVU6|PDE6_DROVI (cGMP-specific 3',5'-cyclic phosphodiesterase OS=Drosophila virilis OX=7244 GN=Pde6 PE=3 SV=1) HSP 1 Score: 395.201 bits (1014), Expect = 1.581e-124 Identity = 221/579 (38.17%), Postives = 326/579 (56.30%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFL--LDVCAE--------KPSNF------------GFHCTLNTENKFSLTSEKIG-------SR------------KIAKMVCINGESFK-CKSEEKLDELKEI-------GISSMICKPIWDSSNHVIGAAQVINKLER-DFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
C G+ NA LFE E+ RN++LL ++EEQN+LE + K + + +E++KCE +VFL LD C E KP F N+F++ E G SR +IA+ V G++ C + + E +I +++C PI ++ VIG AQ+INK F+++D I EA IFC +GI N ++YE+ K A+ +VALE LSYH TA + +++ PI T L S F DF L +++ A +++F+ +++ F I + L +WV++V KNYR V YHNW HA NV M +L + + + D+EILGL+V CLCHDLDHRGTNN FQ KT+SPLA LY +T+E HHF+ VMI+N++GNNIF++L+ + Y ++M ++ +IL+TDL+ +FK R F VEN DW+ E++ LL +MT+CD++A K W V + A LV +EFF QGD+EK QP MMDR +DELP++Q+ +I +C PL+R L +Y+ +EN +W +L K E+
Sbjct: 169 CGIGIQNAQLFEMSVQEYRRNQILLNLARSIFEEQNNLECLVTKIMTEARELLKCERCSVFLVDLDCCEESHLEKIIEKPHQLEQRATRAIKGGDSFEEKQKMRNRFTVLFELGGESQAANVSRPSINDLSHSTLAQIAQFVATTGQTVNICDVHDWVREHNQIRAEGEIDSTHAILCMPIVNAQKTVIGVAQLINKASGLPFTESDASIFEAFAIFCGLGIHNTQMYENACKLMAKQKVALECLSYHATAGQDQTEKLIQDPIAEAETYNLYSFTFTDFDLVDDDTCRAVLRMFMQCNLVSQFHIPYDVLCRWVLSVRKNYRPVKYHNWRHALNVAQTMFAMLKTGKMERFMTDLEILGLLVACLCHDLDHRGTNNAFQTKTESPLAILY-TTSTMEHHHFDQCVMILNSEGNNIFQALSPEDYRSVMKTVESAILSTDLAMYFKKRNAFLELVENGEFDWQGEEKKDLLCGMMMTACDVSAIAKPWEVQHRVAKLVADEFFDQGDLEKLQLNTQPVAMMDRERKDELPKMQVGFIDVICLPLYRVLCDTFPWITPLYEGTLENRRNWQDLAEKVEMG 746
BLAST of Phosphodiesterase vs. TrEMBL
Match: K1Q862 (Phosphodiesterase OS=Crassostrea gigas OX=29159 GN=CGI_10020954 PE=3 SV=1) HSP 1 Score: 464.922 bits (1195), Expect = 5.657e-149 Identity = 234/550 (42.55%), Postives = 345/550 (62.73%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEK----------PSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFK-------CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
L + C ++NA +FE YS E+ RNK LLE +H+L+EEQ S+E + K + + + ++KCE +V L D +E P G +C ++ ++++ ++G+ KIA++V + GE+ + + D S++CKPI + N IG AQV+N+++ F +D+ + EA TIFC +GI NC LYE++ ++A+ VALE LSYH T + +V + + + +L S FNDFSL++++M+LA V++F DL F I E L +W++TV KNYRNVAYHNW HAFNV M L V + + D E L L+V CLCHDLDHRGTNN FQ KT S LAQLYG +ATLE HHFN VMI+N++ +NIF + +++YS +++++K +ILATDLS H + R+KFF+ V++ +W E R +LR LMT+CD+AA TK W + +K A LVM EFF QGD E+N KIQPQ MDR QDELP++Q+ WI +C PL++ L+ +D F+ ++D +++N W L ++
Sbjct: 327 LGTYLTFCGIAIHNAQIFEAYSKEYERNKALLEVVHDLFEEQTSVENVILKIMQRAQSLLKCERCSVLLRDGSSETSFKKVFDLAYPLRNGQNC----QSSDNMSNYQLGN-KIAELVLVTGETINIADAHQDSRFDPNSDGESGFHTRSILCKPIRNRDNQTIGVAQVMNRIDGHSFDDHDDQLFEAFTIFCGLGINNCLLYEEIAVASAKQMVALEVLSYHGTVTAEDVVKLKSRKVADADDWKLDSFNFNDFSLTSDDMLLAAVRIFKDLGFKRTFRIDTEMLCRWILTVRKNYRNVAYHNWRHAFNVCQFMFATLKMSGVRRHISDKESLALVVACLCHDLDHRGTNNAFQQKTSSALAQLYGTKATLEHHHFNHAVMILNSESHNIFGNFNSEEYSEVINLLKDAILATDLSRHIQVRDKFFAMVDSGMKNWDDRESRDILRSILMTTCDVAAITKPWEIQRKVADLVMTEFFDQGDKERNELKIQPQACMDREKQDELPKLQLGWIDGICLPLYKALSNLDASFKPLFDGVLKNRSCWEVLDAE 871
BLAST of Phosphodiesterase vs. TrEMBL
Match: R7UJV1 (Phosphodiesterase OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_169631 PE=3 SV=1) HSP 1 Score: 461.07 bits (1185), Expect = 1.135e-147 Identity = 242/560 (43.21%), Postives = 342/560 (61.07%), Query Frame = 3
Query: 345 SRDFYPMDLH--LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSN-------FGFHCTLNTENKFSLTSEK---IG-SRKIAKMVCINGESFKCKSEE-------KLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
R F+ D L + C NA E Y+ E+ +NK LLE +H+L+EEQ S++ + K + + + +++CE V L D ++ F H + + +S K G S+KIA++V GE+ E + ++ S++CKPI +S+ +IG AQVINK+ F +ND+ + EA TI+C +GI NC LY+ + + A+ VALE LSYH T +V KPIPS + L S KFNDFSL+ +EM+LA +++F D +L F+I+ ETL +W++TV KNYRN+AYHNW HAFNV M +++ + + L D E+L LIVGCLCHDLDHRGTNN FQ K+ SPL+QLYG QATLE HHFN V+I+N++G+NIF + +D Y +M+++KQ+ILATDLS H + R +FF V + DW EQR+LLR LMT+CD+A TK W V ++ A LV+ EF QGD EK + KIQPQ MDR QDELP +Q++WI +C PL++ ++ Q + DQ++EN W L
Sbjct: 300 GRSFFTTDDEKLLETYLAFCGMAFSNAQALEAYTREYEQNKTLLEVVHDLFEEQTSVDDVVMKIMQRAQSLLQCERCVVLLKDAKENSATDKTCFGRVFDLHHSQKKDGSQCRSSTKHKDFGRSKKIAELVAATGETVNIPDAEDDGRFQVNTEHSRDFHTKSLLCKPIRNSNFQIIGVAQVINKIGGSSFDENDQQLFEAFTIYCGLGINNCLLYDKVAAAAAQQAVALEVLSYHATVPTDDVDTFKCKPIPSANQWGLASLKFNDFSLNTDEMILAGIRIFKDTGLLKTFSIEYETLVRWLLTVRKNYRNIAYHNWRHAFNVTQYMFTMINACGIRRHLSDKELLALIVGCLCHDLDHRGTNNAFQQKSSSPLSQLYGTQATLEHHHFNHAVIILNSEGHNIFSKMKSDDYGDVMNLLKQAILATDLSIHVQVRCQFFPLVASGLYDWDDPEQRELLRSVLMTTCDIATITKPWDVQRRVADLVVTEFLDQGDKEKTMLKIQPQAFMDREKQDELPRLQLEWIDGICLPLYKTWQQLNPQLLGVVDQVVENRSRWAVL 859
BLAST of Phosphodiesterase vs. TrEMBL
Match: T1JG26 (Phosphodiesterase OS=Strigamia maritima OX=126957 PE=3 SV=1) HSP 1 Score: 457.218 bits (1175), Expect = 8.748e-146 Identity = 234/537 (43.58%), Postives = 334/537 (62.20%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
L + Q + NA +FET + E+ RN+ LLE +H+L+EEQ SLEK + K++ + + ++KCE AV LL E S+ +N SE + ++A+ V GE ++++ + S++C PI + +IG A++INKL + F +NDE + EA TIFC +GI N ++ +M K+ A+ +VA+E LSYH T E+ + + PIP L F+DF LS EEM+LA V +F DL ++ F I++ETL +W++TV KNYR+V YHNW HAFNV MM + + + DIE LG+ GCLCHDLDHRG NN FQ KT S LA LYG T+E HHFN VMI+N++G+ +F +L++D +S +M+++K SIL+TDLS +F+ REKFFS + N DW++ R+LL LMT+CD+AA+TK W V QK A LV EFF QGD+EK IQPQ +MDR + ELP++QI WI +C PL+++LT ++ + Q M D + N W EL S +S
Sbjct: 347 LETYLQFVGIAITNAQIFETSAREYERNRNLLEVVHDLFEEQISLEKVILKTMQRAQRLLKCERAAVLLLQENHEVNSS-------PKKNPECSMSEAL--LRLAEQVASTGEVLNIAEYLEIEKTNLGTVKSLLCMPIRNRDFQIIGVAKIINKLNGQPFDENDEQLFEAFTIFCGLGINNTMMFNEMEKAMAKQRVAIEVLSYHATIHPKEIEKLKDLPIPDADEWGLHDLSFDDFCLSQEEMILAAVAMFKDLGLINRFNIQKETLLRWLMTVRKNYRDVPYHNWRHAFNVAQMMFALFTTAEMKGIFTDIERLGMFTGCLCHDLDHRGKNNAFQEKTGSALALLYGTTNTMEHHHFNHAVMILNSEGHCLFSNLSSDSFSKVMNVLKHSILSTDLSVYFQNREKFFSLIHNNEYDWQTEGHRELLLSMLMTACDIAASTKPWSVQQKVAELVTSEFFDQGDIEKQELNIQPQALMDRDRKHELPQLQISWIEDICLPLYKNLTNLNSRIQVMVDGAIANKNKWAELASDEGMS 874
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A1U7TRS4 (Phosphodiesterase OS=Tarsius syrichta OX=1868482 GN=PDE11A PE=3 SV=1) HSP 1 Score: 444.891 bits (1143), Expect = 3.791e-145 Identity = 223/550 (40.55%), Postives = 337/550 (61.27%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEKIG------SRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
C + NA LF E+ R++ LLE +++L+EEQ LEK +KK +H+ + ++KCE +V LL+ F C+ + EN F + EK + +A++V G ++++ + + ++D++ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S EV IP S + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV +M +L ++L ++EIL +IVGCLCHDLDHRGTNN FQ K+ S LAQLYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++KQSILATDL+ +F+ R +FF V CDW R + R LMT+CDL A TK W ++++ A LV EFF+QGD E++ K+ P + DR+ +DELP +Q++WI S+C PL++ L V+ + + M D + N W E+ + ++
Sbjct: 8 CGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESMEKSSYSDWQINNSVAELVASTGLPVNISDAYQDPRFDAEVDQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVSKGECDWNIKNHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNVKLKPMLDSIAANRSKWEEMHQEKQLG 557
BLAST of Phosphodiesterase vs. TrEMBL
Match: A0A210QIZ7 (Phosphodiesterase OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT04659 PE=3 SV=1) HSP 1 Score: 454.907 bits (1169), Expect = 8.669e-145 Identity = 237/571 (41.51%), Postives = 339/571 (59.37%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSN----FGFHC----TLNTENKFSLTSEKIG------------------------SRKIAKMVCINGESFK-------CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLER-DFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKS 1967
L + C ++NA +FE YS E+ RNK LLE +H+L+EEQ S+E + K + + + ++KCE +V L D +E N G+ + N +N FS K KIA+ V I GE+ + E ++D+ I + S++CKPI + + IG AQV+NK + F ++D+ + EA TIFC +GI NC LYE+ ++ V LE LSYH S T+V + + +P L +H+FNDFSL+ +EM++A +++F DL + F I E L +W++TV KNYRNV+YHNW HAFNV M L + V + L D E L L+VGCLCHDLDHRGTNN FQ K+ S LA LYG T+E HHFN V I+N++GNNIF + T+++YS ++++K+SILATDLS H + R KFF+ V++ W E ++ LR LMTSCD+A+ TK W + +KAA LVM EFF QGD EK+ IQPQ MDR QDELP++Q+ WI +C PL+ L+ +D F+ + D ++ N +W ++ +
Sbjct: 326 LTTYLTFCGIAIHNAQIFEAYSKEYERNKALLEVIHDLFEEQTSVENVIHKIMQRAQSLLKCERCSVLLRDGTSETNFNQVFDLGYPVKNGKSSNYKNVFSTCDPKTHPANRPRNVPSIICTSPENSSDMKFGNKIAEHVLITGETINISDAEHDGRFEHEVDKCGNISMRSILCKPIRNRDSQTIGVAQVMNKSDGLAFDEHDDQLFEAFTIFCGLGINNCVLYEETAILLSKQAVTLETLSYHAGVSATDVVRLKGQKVPEAPVWNLDNHRFNDFSLTKDEMLVAAIRMFEDLGFIRKFKIDIEVLCRWLLTVRKNYRNVSYHNWRHAFNVCQTMFASLKRSGVKRHLEDRETLALVVGCLCHDLDHRGTNNAFQQKSGSALAHLYGTSGTMEHHHFNHAVTILNSEGNNIFANFTSEEYSGTINLLKESILATDLSLHIQLRNKFFAMVDSGQNTWDDRESKETLRSILMTSCDIASITKPWQIQRKAADLVMAEFFDQGDKEKHQLNIQPQACMDRERQDELPKLQMGWIDGICLPLYTALSKMDAYFEPLKDGVLANRGYWEKMDA 896
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 435.647 bits (1119), Expect = 6.040e-141 Identity = 225/557 (40.39%), Postives = 332/557 (59.61%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
L + C + NA LF E+ R++ LLE +++L+EEQ LEK ++K +H+ + ++KCE +V LL+ F C+ +TEN F + EK + + IA++V G ++++ + + + D+ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S TEV IP + F+DFSL + M+ A +++F++L +L F I ETL +W++TV KNYR V YHNW HAFNV M +L + L ++EIL LIVGC+CHDLDHRGTNN FQ KT S L+ LYG ATLE HHFN VMI+ ++G+NIF +L++ Y LM ++KQSILATDL+ +F+ R FF V+ +W E R + R LMT+CDL A TK W +++K A LV EFF+QGD E++ K+ P + DR+ +DELP +Q++WI +C PL+ L ++ + Q M D + N W EL + + S
Sbjct: 337 LQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMFMELGMLQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSLLTTAGFQETLSELEILALIVGCVCHDLDHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQSEGHNIFSNLSSRDYGDLMQLLKQSILATDLTLYFENRNSFFELVKKGEYNWNVKEHRDMFRSMLMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPSLQLEWIDGICSPLYETLAKLNPKLQPMVDVIQANRAKWDELHQRRQRS 893 HSP 2 Score: 53.9138 bits (128), Expect = 5.607e-7 Identity = 26/85 (30.59%), Postives = 48/85 (56.47%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C PI +S +IG AQ INK F+++DE +++ FC + I+N +L+ K R++ LE ++
Sbjct: 288 DEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVN 372
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11al (dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [Source:NCBI gene;Acc:103024879]) HSP 1 Score: 419.853 bits (1078), Expect = 1.003e-134 Identity = 217/550 (39.45%), Postives = 328/550 (59.64%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFG--FH-----CTLNTENKFSLTSEKIG------SRKIAKMVCINGESFK----CKS---EEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD-FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
L + C + NA LF E+ R++ LLE +++L+EEQ LEK ++K + + +++CE +V LL+ F F C+++ + ++ EK+ + IA++V G C+ + + D+ I S++C PIW+ ++ +IG AQ++N+L+R F+ D+ + EA IFC +GI N +Y + K+ A+ VAL+ LSYH T S EV + IP S + FNDFSL N+ M+ A++++F++L ++ F I E L +W++TV KNYR VAYHNW HAFNV M ++ +VL D E L L+VGCLCHDLDHRGTNN FQ K+ S LA LYG ATLE HHFN VMI+ ++G+NIF +L + +YS +M ++KQ+IL+TDL+ +F+ R KFF V + W E R +LR LMT+CDL A T+ W ++++ A LV EFF+QGD E+ K+ P + DR+ +DELP +Q++WI +C+PL+ L ++++ Q M D + N W EL
Sbjct: 312 LQMYLPFCGISISNAKLFSESRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMQRALTLLQCERCSVLLLEDIHSPVVKFSKTFELMSPLCSVDHD----ISMEKVSCSDWLINNSIAELVASTGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLSYHATCSKVEVDRLKAAKIPLSSELGIDKFHFNDFSLDNDAMITASLRMFLELGVVQKFKIDYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFVMITTAGFQEVLTDTETLALMVGCLCHDLDHRGTNNAFQAKSGSALALLYGTSATLEHHHFNHAVMILQSEGHNIFANLCSKEYSHMMQLLKQAILSTDLTLYFQRRTKFFECVLSGEFSWSIQEHRDVLRSMLMTACDLGAVTRPWEISKQVAELVTSEFFEQGDRERAELKLTPSAIFDRNRKDELPALQLEWIDGICKPLYEALVKLNRKLQPMVDGIDANRKKWEEL 857 HSP 2 Score: 50.8322 bits (120), Expect = 4.975e-6 Identity = 25/84 (29.76%), Postives = 47/84 (55.95%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEAL 980
+++D+L S++C I +S VIG Q INK + F+++DE +++ FC + I+N +L+ + K R++ LE +
Sbjct: 263 DEIDKLTGYKTQSILCMAICNSDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSRALLEVV 346
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11al (dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [Source:NCBI gene;Acc:103024879]) HSP 1 Score: 405.986 bits (1042), Expect = 4.351e-130 Identity = 209/523 (39.96%), Postives = 315/523 (60.23%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFG--FH-----CTLNTENKFSLTSEKIG------SRKIAKMVCINGESFK----CKS---EEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD-FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLF 1880
L + C + NA LF E+ R++ LLE +++L+EEQ LEK ++K + + +++CE +V LL+ F F C+++ + ++ EK+ + IA++V G C+ + + D+ I S++C PIW+ ++ +IG AQ++N+L+R F+ D+ + EA IFC +GI N +Y + K+ A+ VAL+ LSYH T S EV + IP S + FNDFSL N+ M+ A++++F++L ++ F I E L +W++TV KNYR VAYHNW HAFNV M ++ +VL D E L L+VGCLCHDLDHRGTNN FQ K+ S LA LYG ATLE HHFN VMI+ ++G+NIF +L + +YS +M ++KQ+IL+TDL+ +F+ R KFF V + W E R +LR LMT+CDL A T+ W ++++ A LV EFF+QGD E+ K+ P + DR+ +DELP +Q++WI +C+PL+
Sbjct: 312 LQMYLPFCGISISNAKLFSESRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMQRALTLLQCERCSVLLLEDIHSPVVKFSKTFELMSPLCSVDHD----ISMEKVSCSDWLINNSIAELVASTGLPVNISDVCQDPRFDAEADQASGFHIRSVLCVPIWNRTHQIIGVAQILNRLDRKTFNDADQRLFEAFVIFCGLGINNTMMYNQVKKTWAKQSVALDMLSYHATCSKVEVDRLKAAKIPLSSELGIDKFHFNDFSLDNDAMITASLRMFLELGVVQKFKIDYEVLCRWLLTVRKNYRTVAYHNWRHAFNVSQCMFVMITTAGFQEVLTDTETLALMVGCLCHDLDHRGTNNAFQAKSGSALALLYGTSATLEHHHFNHAVMILQSEGHNIFANLCSKEYSHMMQLLKQAILSTDLTLYFQRRTKFFECVLSGEFSWSIQEHRDVLRSMLMTACDLGAVTRPWEISKQVAELVTSEFFEQGDRERAELKLTPSAIFDRNRKDELPALQLEWIDGICKPLY 830 HSP 2 Score: 50.8322 bits (120), Expect = 4.922e-6 Identity = 25/85 (29.41%), Postives = 48/85 (56.47%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C I +S VIG Q INK + F+++DE +++ FC + I+N +L+ + K R++ LE ++
Sbjct: 263 DEIDKLTGYKTQSILCMAICNSDGEVIGVVQAINKNPKGTPFTEDDEKVLQMYLPFCGISISNAKLFSESRKEYDRSRALLEVVN 347
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde11a (phosphodiesterase 11a [Source:ZFIN;Acc:ZDB-GENE-070912-207]) HSP 1 Score: 389.808 bits (1000), Expect = 1.618e-123 Identity = 212/557 (38.06%), Postives = 314/557 (56.37%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
L + C + NA LF E+ R++ LLE +++L+EEQ LEK ++K +H+ + ++KCE +V LL+ F C+ +TEN F + EK + + IA++V G ++++ + + + D+ I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S TEV IP + F+DFSL + M+ A +++F++L +L F I ETL +W++TV KNYR V YHNW HAFNV M +L + L ++EIL LIVGC+CHDLDHRGTNN FQ KT S L+ LYG ATLE HHFN VMI+ ++ + +L +S L S K + R FF V+ +W E R + R LMT+CDL A TK W +++K A LV EFF+QGD E++ K+ P + DR+ +DELP +Q++WI +C PL+ L ++ + Q M D + N W EL + + S
Sbjct: 315 LQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVKFTKSFELLSPKCSADTENSFKDSMEKSSYSDWLINNSIAELVASTGLPVNISDAYQDPRFDAEADQFSGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMFMELGMLQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFSLLTTAGFQETLSELEILALIVGCVCHDLDHRGTNNAFQAKTGSALSLLYGTSATLEHHHFNHAVMILQSEVGTV-NNLQMFMHSRLHSCFKGQL----------NRNSFFELVKKGEYNWNVKEHRDMFRSMLMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPSLQLEWIDGICSPLYETLAKLNPKLQPMVDVIQANRAKWDELHQRRQRS 860 HSP 2 Score: 53.5286 bits (127), Expect = 6.529e-7 Identity = 26/85 (30.59%), Postives = 48/85 (56.47%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C PI +S +IG AQ INK F+++DE +++ FC + I+N +L+ K R++ LE ++
Sbjct: 266 DEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKSPGGALFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVN 350
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Match: pde5ab (cGMP-specific 3',5'-cyclic phosphodiesterase-like [Source:NCBI gene;Acc:103024399]) HSP 1 Score: 337.421 bits (864), Expect = 5.703e-104 Identity = 193/555 (34.77%), Postives = 308/555 (55.50%), Query Frame = 3
Query: 408 LYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTL----------NTENKFSLTSEKIGSRKIAKMVCIN------GESFKCKSEEKLDELKEIGISSMICKPIWDSS-NHVIGAAQVINKLE------RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIM---EKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS*LL 1991
L+NA L+ET E RN+VLL+ ++EEQ SLE ++K + ++ +E VF +D + FH N + S + M +N + F SE + + S++C PI + + VIG Q++NK++ + F++NDE +EA IFC +GI N ++YE + ++ A+ +V LE LSYH +A+ E + +PS + +L F+DF LS+ E A +++F+DLK++ F +K ++L +W+++V KNYR NVAYHNW HAFN M IL + + D+EIL L++ L HDLDHRG NN+F ++D PLAQLY + + +E HHF+ +MI+N+ G+ I SL+ ++Y T + +I+++ILATDL+ + K R +FF +N W R LL+ LMT+CD++A TK WPV ++ A LV EFF+QGD E+ I+P +M+R +D++P +Q+ +I ++C L+ L + + + +N +W L E + LL
Sbjct: 307 LHNAQLYETSQLENRRNQVLLDLASLIFEEQQSLEVLLRKIAATILSFMQAQECTVFTVDGETSNAFSSVFHMEYEELAGSMEFPNRDGDVSKINYMYAQYVKNTMEPLNIPDVTKDQRFPWTSENP--DSPNYHVKSLLCTPIRNGKKDKVIGVCQLVNKMDEATGQVKAFNRNDEQFLEAFAIFCGLGIQNTQMYETVERAMAKQEVTLEVLSYHASAAEEETRALQVTAAATVPSAQSLRLMDFSFSDFDLSDAETTQAAIRMFVDLKLVQNFQMKYKSLCQWILSVKKNYRKNVAYHNWRHAFNTAQCMFAILRSGRLQNNMSDLEILALMIATLSHDLDHRGVNNSFIKRSDHPLAQLYCH-SIMEHHHFDQCLMILNSPGSQILSSLSLEEYKTTLKMIEKAILATDLAVYMKRRTEFFELTKNSQFVWEDECHRDLLKSMLMTACDISAITKPWPVQKRIAELVATEFFEQGDKERRELNIEPIDLMNREKRDKIPSMQVSFIDAICTQLYETLASISDSCSPLLEGCRKNRQNWKLLSEHGEEAGLL 858
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde5ab (phosphodiesterase 5A, cGMP-specific, b [Source:ZFIN;Acc:ZDB-GENE-060824-4]) HSP 1 Score: 333.183 bits (853), Expect = 2.335e-103 Identity = 200/559 (35.78%), Postives = 309/559 (55.28%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFG--FHCTLNTENKFSLTSEK---------IGSRKIAKMVCI-------NGESFKCKSEEKLDELKEIGISSMICKPIWDSS-NHVIGAAQVINKLE------RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEV-----HHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNF-QIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPE 1976
C L+NA L+E E RN+VLLE + EEQ+SLE+ + + + + + C+ AVF+ D + P+ F FH +L TS+ I + + KM+ + F EE+ D + S++C PI + N VIG Q++NKLE R F++NDE +EA IFC + I N R+YE + ++ A+ V LE LSYH A E H+ +PS + L F+DF ++ E + ++++ +DL +L F+I E +W+++V KNYR N+AYHNW HAFN M +L VL +E+L LI+ L HDLDHRG NN++ + ++D PLA LYG+ + LE HHF+ +M++N+ GN + SL+ +Y + + +I+ +IL+TDL+ + K R +FFS V+++ + RKLLR +MT+CD++A TK WPV QK A LV EFF QGD E+ ++P MM+R +D++P IQ+ +I +C PL+ L+ V + N +W +L + P+
Sbjct: 264 CGIVLHNAQLYEDSLLENRRNQVLLELASLVCEEQSSLEELVGRIIDIILSFMPCQRCAVFIAD--KDSPNIFSRVFHKSLEVPGVAENTSQSESRSHPVSFIYAEFVMKMLTLLNIPDVHRDNRFNLPVEERGDYRTK----SLLCAPIQNRKKNEVIGVCQLVNKLEEGAGEVRPFNRNDEQFVEAFAIFCGMAIRNTRMYEAVARAVAKQTVTLEVLSYHAIAHEDECAKLQSQHLTTTSVPSAQSLNLLDFTFSDFGMAEELTAVGSLRMLLDLSLLQTFSIPNEVACRWILSVRKNYRRNIAYHNWRHAFNTGQCMFTVLVTGQAQNVLTPLEMLCLIIAALSHDLDHRGFNNSYIKNRSDHPLATLYGH-SMLEHHHFDQCLMLLNSPGNEMLSSLSVQEYRSAVGMIEHAILSTDLATYCKNRGEFFSLVKDRTFNLEDQHHRKLLRAMMMTACDVSAITKPWPVQQKIAELVASEFFDQGDRERQELHVEPTDMMNREKRDKIPTIQVGFIDGICLPLYEALSCVFPACAPLLSGCQSNRQNWEKLTTSPQ 815 HSP 2 Score: 53.5286 bits (127), Expect = 1.629e-7 Identity = 30/74 (40.54%), Postives = 40/74 (54.05%), Query Frame = 3
Query: 771 SMICKPIWDSSNHVIGAAQVINKL---ERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
S++C PI D+ ++G AQ INK E F++ DE A FC + + N +LYED N R QV LE S
Sbjct: 219 SVLCLPIKDNKGEIVGVAQAINKKGNNEGKFTEKDEREFGAYLAFCGIVLHNAQLYEDSLLENRRNQVLLELAS 292
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 272.707 bits (696), Expect = 9.954e-83 Identity = 162/516 (31.40%), Postives = 274/516 (53.10%), Query Frame = 3
Query: 459 KVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSE-------EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD-FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFN--DFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKK-SVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQAT-LEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
+ LL+ L+ + + + + + + + + E +VFLLD + + F + ++ + + + IA V GE K +D+ S++C PI D + VIG A++ NK+ FSK DED+ A +I+C + I N LY+ + ++ R+Q++ E + YH S E++ ++ I + + KF SL ++ + A + + D+ + + + TL +W + V K YR+ YHNW HA++V H Y+L+K + + L D+EI L V CLCHDLDHRGTNN+FQ+ + S LA LY ++ + +E+HHF + I+N+ G NI E+L+ +Y ++ +++ ILATDL++H + K ++ + + + Q LL LMTSCDL+ TK W +K A L+ +EFF QGD+EK + +P MMDR + +PE+QI ++ + PLF+ L + E+Y+++ N HW + K
Sbjct: 76 QALLQVAKNLFTHLDDVSVLLHEIIQEARNLSNAERCSVFLLDRSSHELVAKVFDGGVVSDESYEVRIP--ADQGIAGHVATTGEVLNIKDAYSHPLFYRGVDDSTGFRTRSILCFPIKDENEEVIGVAELCNKINGPWFSKFDEDLATAFSIYCGISIANSLLYKKVAEAQQRSQLSNEMMMYHMKVSPEEMNKVLNSRIQTVTDIHPDFAKFTYTPRSLGEDQTITAILGMVEDMGFINNYKLDLRTLTRWCLMVRKGYRDPPYHNWMHAYSVSHF-CYLLYKNLDLGKYLQDMEIFALFVSCLCHDLDHRGTNNSFQVDSKSVLAALYSSEGSVMERHHFAQAIAIINSAGCNILENLSRKEYQRMLDLMRDIILATDLAHHLRIF-KDLRKIADAGYNPDNGHQHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGN-RPSEMMDRE-KAYIPELQISFMEHIAMPLFKLLKDMLPGAAELYERVAANKEHWMRVSHK 585
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE2A (phosphodiesterase 2A [Source:HGNC Symbol;Acc:HGNC:8777]) HSP 1 Score: 194.897 bits (494), Expect = 4.834e-56 Identity = 117/368 (31.79%), Postives = 196/368 (53.26%), Query Frame = 3
Query: 531 VHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKI-GSRKIAKMVCINGESFKCKSE-------EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD-FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYH----TTASLTEVHHIMEKPIPSFSTSQLGSHKFN--DFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKK-SVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQAT-LEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFK 1583
+ + + + E +VFLLD + + F + ++ +I + IA V GE K +D+ S++C PI D + VIG A++ NK+ FSK DED+ A +I+C + I N LY+ + ++ R+Q++ E + YH T S E++ ++ I + + KF SL ++ + A + + D+ + + + TL +W + V K YR+ YHNW HA++V H Y+L+K + + L D+EI L V CLCHDLDHRGTNN+FQ+ + S LA LY ++ + +E+HHF + I+N+ G NI E+L+ +Y ++ +++ ILATDL++H +
Sbjct: 15 IQEARNLSNAERCSVFLLDRSSHELVAKVFDGGVVSDEFMKSYEVRIPADQGIAGHVATTGEVLNIKDAYSHPLFYRGVDDSTGFRTRSILCFPIKDENEEVIGVAELCNKINGPWFSKFDEDLATAFSIYCGISIANSLLYKKVAEAQQRSQLSNEMMMYHMKVGTQVSPEEMNKVLNSRIQTVTDIHPDFAKFTYTPRSLGEDQTITAILGMVEDMGFINNYKLDLRTLTRWCLMVRKGYRDPPYHNWMHAYSVSHF-CYLLYKNLDLGKYLQDMEIFALFVSCLCHDLDHRGTNNSFQVDSKSVLAALYSSEGSVMERHHFAQAIAIINSAGCNILENLSRKEYQRMLDLMRDIILATDLAHHLR 381
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: pde1a (phosphodiesterase 1A, calmodulin-dependent [Source:ZFIN;Acc:ZDB-GENE-090831-2]) HSP 1 Score: 128.257 bits (321), Expect = 1.414e-31 Identity = 81/260 (31.15%), Postives = 138/260 (53.08%), Query Frame = 3
Query: 1122 KLFIDLKILTLFTIKQETLYKWVITVMKNY--RNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNI-YKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLT 1892
+L ++++ + I L +V + Y YHN HA +V + Y+L + + L ++E L +I HDL+H GT NNF I+T S +A LY ++A LE HH + +M +D NIF +L+ D + L +++ + +LATD+S HF+ + S ++ S ++ K + L+ + D++ TK+WP+ Q+ +MEEFF+QGD E + P + DR+ + + QI ++ + EP F LT
Sbjct: 175 ELLTRYELISRYKIPVAALVSFVEALEAGYSKHKNPYHNLAHAADVTQTVHYLLLQSGLMHWLSELETLAVIFAAAIHDLEHTGTTNNFHIQTRSDVALLYNDRAVLENHHVSAAYRLMQDDDMNIFINLSKDDWRELRALVVEMVLATDMSCHFQQIKTMKSALQQPE----SIDKSKAM-SLLLHAGDISHPTKEWPLHQRWTEALMEEFFRQGDREAKLGLPFSP--LCDRNST-MVAQSQIGFMDFIVEPTFSVLT 426
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Match: PDE1C (phosphodiesterase 1C [Source:HGNC Symbol;Acc:HGNC:8776]) HSP 1 Score: 116.701 bits (291), Expect = 3.893e-28 Identity = 77/260 (29.62%), Postives = 131/260 (50.38%), Query Frame = 3
Query: 1122 KLFIDLKILTLFTIKQETLYKWVITVMKNY--RNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGN-NIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLT 1892
+LF ++ F I ++ +V + Y YHN HA +V + Y++ K L ++EIL +I HD +H GT NNF I+T S A LY +++ LE HH + +M D NI +L+ D + L +++ +++LATD+S HF ++N E+ K + ++ + D++ K W + ++ + +MEEFF+QGD E + + + DR+ +P+ QI +I + EP F LT
Sbjct: 166 ELFTRYDLIARFKIPVSSVVSFVEALEAGYSKHKNPYHNSVHAADVTQTVHYLMLKTGTIHWLNELEILSMIFAAAIHDYEHTGTTNNFHIQTRSDSAILYNDRSVLENHHVSAAYRLMQEDEEMNILINLSKDDWRELRALVVETVLATDMSCHFHQ----LKSIKNLLQQPEGVEKPKAM-SLMLHTADISHPAKNWNLHRRWTMSLMEEFFRQGDKEAEL-GLSFSPLCDRNAT-MVPQSQIGFIDYIVEPTFTVLT 418
BLAST of Phosphodiesterase vs. Ensembl Yeast
Match: PDE2 (High-affinity cyclic AMP phosphodiesterase; component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon [Source:SGD;Acc:S000005887]) HSP 1 Score: 60.8474 bits (146), Expect = 3.716e-10 Identity = 66/258 (25.58%), Postives = 112/258 (43.41%), Query Frame = 3
Query: 1038 PSFSTSQLGSHKFN-----DF---SLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNV-AYHNWCHAFNV----FHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSI-------IKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEF 1751
P SQ GSH +N DF SLS +E++ L L I L + T+ +Y V +HN+ HA +V + + Y+L V +LL + +G HD+ H GTNN +S +AQ + N + LE H L F+ L ++ + L+SI I ++ILATD++ H + ++ E + ++ L ++ + D++ T+ ++ + A L+ EF
Sbjct: 193 PIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWRLCTYLLKDNPVQTLLLCMAAIG-------HDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHREL------------FQQLLSEHWPQLLSISKKKFDFISEAILATDMALHSQYEDRLMHE---------NPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEF 422
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO43657 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY89]) HSP 1 Score: 416.387 bits (1069), Expect = 5.209e-136 Identity = 221/549 (40.26%), Postives = 329/549 (59.93%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLL-------------DVCAEKPSN--FGFHCTLNTE--NKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEI------GISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
C G+ NA LFE + EF+RN+ LLE +H+++EEQ SLEK + K + + ++KCE+ +V LL SN +GF L +E N S TS ++AK+V G++ + L + G S ++C PI ++ +IG A++IN+L+ + F +NDE + EA IFC +GI N +Y+ M ++ A+ QVALE LSYH A TEV I + +P L S KF+DFSL+ ++M++A++++F D + F I E L +W++TV NYRNV YHNW HAFNV M +L + V+ +E LGLIVGCLCHDLDHRGTNN FQ KTDSPL++LYG +TLE HHFN V+I++ +G F + +D+Y ++S IK SIL+TDL+ +FK R KFF+ VE+ D + + R +L+ +MT+CDL TK W + ++ LV EFF+QGD+E+ Y ++P +MDR DELP++Q+Q+ + P+F+ L ++ + Q + D N W +L ++
Sbjct: 182 CGIGITNAKLFELSAIEFNRNRALLELVHDIFEEQTSLEKVVHKIMKRALGLLKCEKCSVLLLTQPELRFSRVFNLKTTGRITSNTRYGFILLLVSEGHNDRSFTS------RVAKLVAATGKTMNIPDASQDTRLADSSNVEKKGFSPILCMPIRNNKFEIIGVAELINRLDNKPFDENDETLFEAFAIFCGLGIHNTMIYDQMARAKAKQQVALEVLSYHVAAKKTEVEKIRDTQVPKAVDINLHSFKFDDFSLAADDMLIASLRMFKDCGFIEEFHIDYEVLSRWILTVKNNYRNVIYHNWRHAFNVAQSMFCMLTTGGMASVITKLECLGLIVGCLCHDLDHRGTNNAFQAKTDSPLSKLYGT-STLEHHHFNHAVIILSTEG---FSPILSDEYRQVISYIKHSILSTDLATNFKQRPKFFALVESGEFDPYNMDHRDMLKAMMMTACDLNGTTKPWEIQKEVVNLVTREFFEQGDMERERYNMEPMAIMDRQKIDELPKLQVQFFETTGLPVFKVLAKLNNKLQPLVDGAESNKRRWQKLDAE 720 HSP 2 Score: 55.4546 bits (132), Expect = 5.872e-8 Identity = 31/90 (34.44%), Postives = 49/90 (54.44%), Query Frame = 3
Query: 771 SMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTE-VHHIMEK 1031
S++CKP+ ++ V+G AQ+INK F+K DE + + FC +GITN +L+E L A+ ++ +L E VH I E+
Sbjct: 138 SLLCKPVKNNEGEVVGVAQIINKNPGGVPFTKEDEKVCDMYLTFCGIGITNAKLFE------------LSAIEFNRNRALLELVHDIFEE 215
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO39522 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9Q1]) HSP 1 Score: 387.111 bits (993), Expect = 1.705e-123 Identity = 207/542 (38.19%), Postives = 318/542 (58.67%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSE------------KIGSRKIAKMVCINGESFKC-------KSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
C G+ NA L+E E RN+VLL+ ++EEQ SL + K + + +++CE +V L+D S F + E K L ++ IG I V GE+ + + +D++ +++C PI ++S +IG Q++NK++ F+KNDE++ EA IFC + I + +YE++ K+ A+ +VALE LSYH + L E + E+P+P ++ +L F+D S+S+++ + + + DLKI+ F I TL ++V+T+ KNYR V YHNW HAFNV M +L K S+ + IE LIV CL HDLDHRGTNN+FQIK+ +PLAQLY +T+E HHF+ +MI+N+ GN IF +L+ D+Y+ ++ +++ SI+ATDL+ +F+ R FF +VEN+ DW + LLR +MT+CDL+A TK W V ++ A LV EEFFQQGD+E+ P MDR +DELP++Q+ +I +VC PL++ + D + + D EN W +L
Sbjct: 282 CGIGINNAELYERAQLEIRRNQVLLDLARTIFEEQTSLHNIVHKIMMITQSLLQCERCSVLLVD----PTSKTLFAQAFDLEAKDYLQNDDDDKTVEVRFPINIG---ITGHVATTGETLNIPDAYADERFDPTVDQVSGFTTKTILCMPIKNASGDIIGVVQLLNKVDGTPFNKNDENLFEAFAIFCGMAIHSTVMYENVNKAMAKRKVALEVLSYHAVSPLEEAIKLKEEPLPPITSLRLIDFAFDDMSISDDDTLKGCLAMLCDLKIVETFQIDYLTLCRFVLTIKKNYRPVMYHNWRHAFNVAQTMYAMLKKPSIGKYFTVIEQYALIVACLSHDLDHRGTNNSFQIKSATPLAQLYST-STMEHHHFDQCIMIINSQGNEIFNTLSADEYNKIIKLLEASIIATDLALYFQRRGDFFKKVENRELDWSDDSSKDLLRAMMMTACDLSAITKPWLVQKRTAHLVAEEFFQQGDLEQEELHSTPLPTMDRRKKDELPQMQVGFIDAVCLPLYKAFSQFDDNLKVLKDGCRENRRQWQKL 815 HSP 2 Score: 56.225 bits (134), Expect = 3.637e-8 Identity = 35/91 (38.46%), Postives = 47/91 (51.65%), Query Frame = 3
Query: 771 SMICKPIWDSSNHVIGAAQVINKLERD----FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEK 1031
S++C PI D VIG AQVINK + F+ +DE I +FC +GI N LYE R QV L+ L+ T +H+I+ K
Sbjct: 236 SILCMPIKDHDGEVIGVAQVINKTGKSTDSAFTIDDEQIFLKYLVFCGIGINNAELYERAQLEIRRNQVLLD-LARTIFEEQTSLHNIVHK 325
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO42681 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0H3]) HSP 1 Score: 252.677 bits (644), Expect = 4.828e-79 Identity = 117/263 (44.49%), Postives = 166/263 (63.12%), Query Frame = 3
Query: 1182 KWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
+W+++V KNYR V YHNW HAFNV M I+ S+ + D+E+ LIV CLCHDLDHRGTNN FQ KTDSPLA LY +T+E HHF+ +MI+N +GNNIF ++ ++Y + I++ +IL+TDL+ +FK R F + N DW + R+LLR +MT+CD+AA TK W + + A +V EFF QGD+EK +P MMDR ++ELP +Q+ +I +C P++ ++ + + D N HW EL K
Sbjct: 3 RWLLSVKKNYRPVKYHNWRHAFNVAQSMFTIMKTGSLCKYFSDLEVFALIVACLCHDLDHRGTNNAFQTKTDSPLAALYST-STMEHHHFDHCIMILNGEGNNIFSEMSPEEYRDTIKILEHAILSTDLALYFKKRGTFQEILAEPNVDWSADNNRELLRAMMMTACDVAAITKPWEIQRVVAEMVASEFFDQGDLEKEKLNAEPIPMMDRRKKNELPSMQVGFIDFICLPIYELFYKLEPSLKPLLDGCQSNRRHWQELGEK 264
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO44626 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RVE3]) HSP 1 Score: 260.381 bits (664), Expect = 9.531e-78 Identity = 162/521 (31.09%), Postives = 272/521 (52.21%), Query Frame = 3
Query: 408 LYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEK----IGSRKIAKMVCINGESFKCKSEEKLDEL-KEIGISS------MICKPIWDSSNHVIGAAQVINK----LERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYD 1925
LY A ++ + LL ++++ S++ + K ++ + ++ + ++FL+D + F + E+ S +K ++ +A V +GE+ D +EI I + ++C PI+ N +IG Q++NK L FS +DE + I+C + + + +LY+ + +S + +VALE LSYH+ S E+H + E P L +++F+ +SL +E V+ + +F + +L + LY++V+TV KNYR V YHNW HAF V H M ++ +S +E L + CLCHDLDHRG N++ +PLA +Y + +T+E HHFN T+ I+ ++G+NIF L + +Y T++ +K+ ILATDL+ F + K V+ W E R+LLR MT+CDL+A TK W + K ++ +EF+ +GD+EK K QP M DR+ ELP Q+ ++ +C P + L V + + D
Sbjct: 102 LYYAEMYLHMHKHRKLTEFLLNVTRSIFQDIVSMDTVIMKIMNYAQTLVDADRTSLFLVDNKTNELYARIFDIGGSLEDSRSSQLQKEIRFPKTKGVAGYVATSGETLNISDAYHDDRFNREIDIQTGYTTRTLLCMPIFIRGN-IIGVVQMVNKKSGVLIMCFS-SDEKSFQTFAIYCGLALHHAKLYDKIRRSEQKHRVALEVLSYHSKCSEGELHRLKELDCPD-PYPDLETYEFDSYSLDSE--VMPKLVIFQTRNLFSLSRFDLDELYRFVLTVRKNYRKVPYHNWTHAFAVAHCMYLVI--RSGHNNFTGLEALAMFFACLCHDLDHRGRTNSWMKNEGTPLAAVY-STSTMEHHHFNQTITILQHEGHNIFSQLNSAEYKTVLGYMKECILATDLALFFGNKAKLKDVVDKGTFSWDDQEHRRLLRAICMTACDLSACTKPWRIQYKIVEVIYQEFYAEGDLEKAQGK-QPIPMKDRNTAHELPAHQVGFLVGICLPCYELLGKVIPGTKPLVD 613
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Match: EDO32088 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SW30]) HSP 1 Score: 225.713 bits (574), Expect = 5.186e-65 Identity = 145/501 (28.94%), Postives = 244/501 (48.70%), Query Frame = 3
Query: 456 NKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEK---------PSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDEL-KEIGISS------MICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEK------PIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFH-MMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHL 1889
N LL + +++E +++ ++K + K+++ + ++FLLD +E+ + F C E +F + S+ IA V G + + + +E+ + + ++C P+ +IG Q++N FS ND E +C + + ++Y + + + QVALE +SYH AS E + P + S L + L + +F + ET+ ++ ++V K YR++ YHNWCHAF+V H + I I KS+T D E L L + +CHD+DHRG NN F + +PLA LY +T+E HHF V I+ ++G N+F L + Y ++ +I+++I+ATDL F +++ + EN+ W + R L+R LMT+CDL + K W + A V EEF+ QGD E+ + + P MMDRS D+LPE Q+ ++ + P + L
Sbjct: 123 NTFLLNVVRSIFDEVCTMDTVIEKIMAFAKKLVNADRCSLFLLDQASEELFANLFDDGNEDGSFRC--GNEIRFPV------SKGIAGYVACTGSILNIRDAYRDERFNREVDMKTGYTTHTILCVPV-RCKGSIIGVCQMVNSHNGFFSPNDMQSFEMFAGYCGLALHYSKMYNSLFCAQQKHQVALEVISYHCCASEKETEEFLNSADLVMLPPAYYPFSYLSA-----------------------LIFVLIFRVDLETIARFSLSVRKCYRDIPYHNWCHAFSVAHSLWIVIRDNKSLT----DYEKLSLFIAGICHDVDHRGKNNAFMLHCKTPLANLY-TTSTMEWHHFKQGVFILESEGQNVFGQLDAESYRRVLELIQEAIIATDLMLFFGNKKELETLQENKAFRWEEEKHRSLIRCLLMTACDLCTSAKPWDIQVVAVNKVFEEFYIQGDEERKM-GLDPLPMMDRSKHDDLPENQVGFLKGIVRPCYSLL 585
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde11a (phosphodiesterase 11A [Source:NCBI gene;Acc:101163533]) HSP 1 Score: 433.335 bits (1113), Expect = 7.076e-140 Identity = 223/553 (40.33%), Postives = 332/553 (60.04%), Query Frame = 3
Query: 375 LNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNF-------GFHCTLNTENKFSLTSEK------IGSRKIAKMVCING------ESFK-CKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLE-RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSK 1970
L + C + NA LF E+ R++ LLE +++L+EEQ LEK ++K +H+ + ++KCE +V LL+ F C+ + E+ F + EK + + +IA++V G ++++ + + + D+ + I S++C PIW+S++ +IG AQV+N+L+ + F D+ + EA IFC +GI N +Y+ + KS A+ VAL+ LSYH T S TEV IP + F+DFSL + M+ A +++F++L ++ F I ETL +W++TV KNYR V YHNW HAFNV M +L +VL D+EIL LIVGC+CHDLDHRGTNN FQ KT S LA LYG ATLE HHFN VMI+ ++G+NIF +L++ +YS LM ++K SILATDL+ +F+ R FF V +W R + R +MT+CDL A TK W +++K A LV EFF+QGD E+ K+ P + DR+ +DELP +Q++WI +C PL+ L ++ + Q M+D++ N W EL K
Sbjct: 318 LQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVNDLFEEQTDLEKIVRKIMHRAQTLLKCERCSVQLLEDIESPVVRFTKSFELLSPKCSADAESSFKDSMEKSSYSDWLINNRIAELVASTGLPVNISDAYQDPRFDAEADQFSDFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKTEVDKFKAANIPLVCELGIDKLSFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQCMFAMLTTAGFQEVLTDLEILALIVGCVCHDLDHRGTNNAFQAKTGSALALLYGTSATLEHHHFNHAVMILQSEGHNIFSNLSSTEYSDLMQLLKLSILATDLTLYFENRNMFFDLVSKGEYNWNVKAHRDMCRSMMMTACDLGAVTKPWDISRKVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPGLQLEWIDGICAPLYETLVKLNPKLQPMFDRIRANRSKWEELNKK 870 HSP 2 Score: 54.299 bits (129), Expect = 4.686e-7 Identity = 26/85 (30.59%), Postives = 48/85 (56.47%), Query Frame = 3
Query: 735 EKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERD--FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALS 983
+++D+L S++C PI +S +IG AQ INK F+++DE +++ FC + I+N +L+ K R++ LE ++
Sbjct: 269 DEIDKLTGYKTKSLLCMPIHNSDGEIIGVAQAINKTSNGELFTEDDEKVLQMYLPFCGIAISNAQLFAASRKEYDRSRALLEVVN 353
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde5ab (phosphodiesterase 5A [Source:NCBI gene;Acc:101173207]) HSP 1 Score: 338.961 bits (868), Expect = 1.014e-104 Identity = 191/542 (35.24%), Postives = 301/542 (55.54%), Query Frame = 3
Query: 408 LYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFH----------------CTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWD-SSNHVIGAAQVINKLE------RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
L+NA L+ET E RN+VLL+ ++EEQ LE ++K + ++ + VF+ D + + FH C + N K + + + F S+ D + I S++C PI + + VIG Q++NKL+ + F++NDE +EA IFC +GI N ++YE + ++ A+ +V LE LSYH +A+ E + +PS + +L F+DF LS+ E LAT+++F DL ++ F +K +L +W+++V KNYR +VAYHNW HAFN M +L + L D+EIL L++ L HDLDHRG NN++ +++ PLAQLY + +T+E HHF+ +MI+N GN I L+ D+Y + +I+++ILATDL+ + K RE FF +N W R LLR LMT+CD++A TK WPV ++ A LV EFF+QGD E+ I+P +M+R +D++P +Q+ +I ++C L+ L + + + + +N HW L
Sbjct: 295 LHNAQLYETSQLENKRNRVLLDLATLIFEEQQCLEVLLRKIAGTILSFMQAQACTVFIADEESMNSFSGVFHMEHEELSEVLEDPKRNCDVKQINYMFAQYVKSTMQPLNISDVTKDQRFPWTSDCP-DHMSN-QIKSLLCAPIRNRKKDKVIGVCQLVNKLDEASGSIKSFNRNDEQFLEAFAIFCGLGIQNTQMYETVERAMAKQEVTLEVLSYHASATEEESQELQVATVPSAQSLRLLDFSFSDFDLSDTETTLATIRMFTDLNLVQNFQMKYTSLCQWILSVKKNYRKSVAYHNWRHAFNTAQCMFALLKSGRLQNNLSDLEILALMIATLSHDLDHRGVNNSYIQRSEHPLAQLYCH-STMEHHHFDQCLMILNTPGNQILSGLSLDEYKATLKMIEKAILATDLALYMKKREDFFELTKNNQFVWVDEHHRDLLRSMLMTACDISAITKPWPVQKRVAELVATEFFEQGDKERRELNIEPTDLMNREKRDKIPSMQVSFIDAICIQLYETLAGLLEHCSPLLEGCQKNRQHWKRL 833
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde5ab (phosphodiesterase 5A [Source:NCBI gene;Acc:101173207]) HSP 1 Score: 338.961 bits (868), Expect = 1.935e-104 Identity = 191/542 (35.24%), Postives = 301/542 (55.54%), Query Frame = 3
Query: 408 LYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFH----------------CTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWD-SSNHVIGAAQVINKLE------RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
L+NA L+ET E RN+VLL+ ++EEQ LE ++K + ++ + VF+ D + + FH C + N K + + + F S+ D + I S++C PI + + VIG Q++NKL+ + F++NDE +EA IFC +GI N ++YE + ++ A+ +V LE LSYH +A+ E + +PS + +L F+DF LS+ E LAT+++F DL ++ F +K +L +W+++V KNYR +VAYHNW HAFN M +L + L D+EIL L++ L HDLDHRG NN++ +++ PLAQLY + +T+E HHF+ +MI+N GN I L+ D+Y + +I+++ILATDL+ + K RE FF +N W R LLR LMT+CD++A TK WPV ++ A LV EFF+QGD E+ I+P +M+R +D++P +Q+ +I ++C L+ L + + + + +N HW L
Sbjct: 326 LHNAQLYETSQLENKRNRVLLDLATLIFEEQQCLEVLLRKIAGTILSFMQAQACTVFIADEESMNSFSGVFHMEHEELSEVLEDPKRNCDVKQINYMFAQYVKSTMQPLNISDVTKDQRFPWTSDCP-DHMSN-QIKSLLCAPIRNRKKDKVIGVCQLVNKLDEASGSIKSFNRNDEQFLEAFAIFCGLGIQNTQMYETVERAMAKQEVTLEVLSYHASATEEESQELQVATVPSAQSLRLLDFSFSDFDLSDTETTLATIRMFTDLNLVQNFQMKYTSLCQWILSVKKNYRKSVAYHNWRHAFNTAQCMFALLKSGRLQNNLSDLEILALMIATLSHDLDHRGVNNSYIQRSEHPLAQLYCH-STMEHHHFDQCLMILNTPGNQILSGLSLDEYKATLKMIEKAILATDLALYMKKREDFFELTKNNQFVWVDEHHRDLLRSMLMTACDISAITKPWPVQKRVAELVATEFFEQGDKERRELNIEPTDLMNREKRDKIPSMQVSFIDAICIQLYETLAGLLEHCSPLLEGCQKNRQHWKRL 864
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: pde5ab (phosphodiesterase 5A [Source:NCBI gene;Acc:101173207]) HSP 1 Score: 337.421 bits (864), Expect = 2.006e-104 Identity = 192/556 (34.53%), Postives = 301/556 (54.14%), Query Frame = 3
Query: 408 LYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDV---------------------------CAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWD-SSNHVIGAAQVINKLE------RDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPI---PSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYR-NVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTEL 1961
L+NA L+ET E RN+VLL+ ++EEQ LE ++K + ++ + VF+ D C K N+ F + + + S+ ++ VCIN I S++C PI + + VIG Q++NKL+ + F++NDE +EA IFC +GI N ++YE + ++ A+ +V LE LSYH +A+ E + + PS + +L F+DF LS+ E LAT+++F DL ++ F +K +L +W+++V KNYR +VAYHNW HAFN M +L + L D+EIL L++ L HDLDHRG NN++ +++ PLAQLY + +T+E HHF+ +MI+N GN I L+ D+Y + +I+++ILATDL+ + K RE FF +N W R LLR LMT+CD++A TK WPV ++ A LV EFF+QGD E+ I+P +M+R +D++P +Q+ +I ++C L+ L + + + + +N HW L
Sbjct: 258 LHNAQLYETSQLENKRNRVLLDLATLIFEEQQCLEVLLRKIAGTILSFMQAQACTVFIADEESMNSFSGVFHMEHEELSEVLEDPKRNCDVKQINYMFAQYVKSTMQPLNISDVTKDQRFPWTVCINQ------------------IKSLLCAPIRNRKKDKVIGVCQLVNKLDEASGSIKSFNRNDEQFLEAFAIFCGLGIQNTQMYETVERAMAKQEVTLEVLSYHASATEEESQELQVTAVATVPSAQSLRLLDFSFSDFDLSDTETTLATIRMFTDLNLVQNFQMKYTSLCQWILSVKKNYRKSVAYHNWRHAFNTAQCMFALLKSGRLQNNLSDLEILALMIATLSHDLDHRGVNNSYIQRSEHPLAQLYCH-STMEHHHFDQCLMILNTPGNQILSGLSLDEYKATLKMIEKAILATDLALYMKYREDFFELTKNNQFVWVDEHHRDLLRSMLMTACDISAITKPWPVQKRVAELVATEFFEQGDKERRELNIEPTDLMNREKRDKIPSMQVSFIDAICIQLYETLAGLLEHCSPLLEGCQKNRQHWKRL 794
BLAST of Phosphodiesterase vs. Ensembl Medaka
Match: ENSORLT00000039837.1 (cGMP-specific 3',5'-cyclic phosphodiesterase-like [Source:NCBI gene;Acc:101167929]) HSP 1 Score: 286.189 bits (731), Expect = 2.308e-84 Identity = 169/534 (31.65%), Postives = 289/534 (54.12%), Query Frame = 3
Query: 408 LYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGS-----RKIAKMVCINGESFKCKSEEKLDEL-----KEIGISSMICKPIW-DSSNHVIGAAQVINKLERD------FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRN-VAYHNWCHAFNVFHMMIYIL-HKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHW 1952
L N L+E+ E R+ L++ L E +S E + K + + +F + A++ S T + L E++G+ R+ + I+ S+ C++ + + L E + S+IC P+ + S +VI Q++NK +D F++ DE ++E + ++C + + A +V E L+YH TA+ E+ + E IPS + + F+DF L + AT+++F+DLK++ F I ++L +WV+TV + YRN V YHNW HA M +L + + +EIL L++ L HD+DHRG NN++ +T PLAQLYG+ ++LE HH+NL + I+NN G+ I SL+++ + ++ ++K++ILATDL+ + + R++FFS VE W+ +Q+ LLR LMT+ DL+A K WP ++ A LV EFF QGD E+ +KI+P +M+R LP +Q+++I +C PL++ ++ + + D ++N +W
Sbjct: 374 LDNIQLYESSRQEAKRSHALIKMAQVLSREHHSFEVLLSKMAATIMPSTGAQYCTIF---IPADQTSVIDNKVTFS--RVIHLECEELGATCQIYRRERDISDID-PSYACQTLKTMKTLNMAKCSEESVRSIICCPVRNERSENVIAVCQLMNKQSKDSDDLEAFNRYDECLLEDLAVYCGLALQYSEAVHITEVRRASVKVTQEVLAYHITAAEQEIQALQEATIPSAESLNIIDFNFSDFGLPEDMTTQATIRMFLDLKLVQEFNIDYKSLCQWVLTVRRGYRNNVPYHNWSHALCTAQSMFAMLMSTDQLHNIFSRLEILALMIATLNHDIDHRGVNNSYIERTKQPLAQLYGH-SSLENHHYNLCLFILNNTGSQILRSLSSEDHRNVLHMVKRAILATDLNVYMQRRKEFFSLVEKNRMKWKCEKQKDLLRSMLMTASDLSAIAKPWPEQKRIANLVAMEFFAQGDKEREEFKIRPIDIMNRENSTRLPHMQVEYIDEICYPLYKAVSQLFDACSPLRDGCVKNRENW 900
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000026730.1 (SMESG000026730.1) HSP 1 Score: 1176.77 bits (3043), Expect = 0.000e+0 Identity = 564/564 (100.00%), Postives = 564/564 (100.00%), Query Frame = 3
Query: 291 MNYEFLLYAYKLPTIISCSRDFYPMDLHLNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
MNYEFLLYAYKLPTIISCSRDFYPMDLHLNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS
Sbjct: 1 MNYEFLLYAYKLPTIISCSRDFYPMDLHLNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 564
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000026730.1 (SMESG000026730.1) HSP 1 Score: 1123.61 bits (2905), Expect = 0.000e+0 Identity = 540/540 (100.00%), Postives = 540/540 (100.00%), Query Frame = 3
Query: 363 MDLHLNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
MDLHLNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS
Sbjct: 1 MDLHLNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 540
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000026730.1 (SMESG000026730.1) HSP 1 Score: 1116.29 bits (2886), Expect = 0.000e+0 Identity = 537/537 (100.00%), Postives = 537/537 (100.00%), Query Frame = 3
Query: 372 HLNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 1982
HLNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS
Sbjct: 268 HLNQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCKSEEKLDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPEIS 804
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000019038.1 (SMESG000019038.1) HSP 1 Score: 357.451 bits (916), Expect = 3.583e-111 Identity = 188/541 (34.75%), Postives = 313/541 (57.86%), Query Frame = 3
Query: 396 CVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAEKPSNFGFH------CTLNTENKFSLTSEKIGSRK------IAKMVCINGESFKCKS---EEKLDELKEIGIS----SMICKPIWDSSNHVIGAAQVINKLERD-FSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVEN--QNCDWRSAEQRKLLRDALMTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHW 1952
C + NA ++ E RN+VLL+ ++EEQ+S+++ M K + + +++CE V + L+ K + +NTE+ E G+ + I+ V GE+ +E+ D+ ++ +++C PI S+ V+ Q+ NK++ + F++ D + EA +FC +GI N +YE++T++ AR ++ LE LSYH A + + + + IPS +L F DF++++++ + +++F+DL ++ LF I L +W+++V KNYR V YHNW HAFNV M ++ ++ V ++EI+ L++ CLCHDLDHRGTNN FQ+KT SPLA+LY + LE HHF+ +M ++ G+++ ++ Y T++ +I+++ILATDL+ +F+ R+ FF V + + DW E+R LLR MT+CD+AA TK W +K A LV EFF+QGD+EK I+P MMDR +DELP++Q+++I +C PL++ +T V + +EN HW
Sbjct: 360 CGMNIRNAQIYRQSQLETRRNQVLLDLARLIFEEQSSMKRLMFKIMMHTQSLLQCERVQILLVGNVNHKDNKIFTRIYEYNESEINTED----LCESFGNSRFPINIGISGYVAKTGETVNISDAYEDERFDKSVDLNTPFHTQAILCMPIKSSTGQVLSVCQLTNKIQGECFTQTDIYLFEAFGLFCGLGIHNTHMYEEITRAMARQRITLEVLSYHAIAPIEDAVKLSKMLIPSLRYHKLNQFIFTDFNMTDDDTIKGCIRMFVDLNLINLFNIDYVVLCRWLLSVKKNYRQVTYHNWRHAFNVAQTMFTMIQTGKLSLVFSNVEIIALLIACLCHDLDHRGTNNQFQVKTMSPLAELYST-SVLEHHHFDQCIMTLSTKGSDMLCNVNHHDYQTIVVLIEEAILATDLAMYFQKRKGFFDIVSDIPEIYDWSCDEERSLLRSMCMTACDVAAITKPWDAQRKIAELVASEFFEQGDLEKTELNIKPIAMMDRDKKDELPKLQVEFIDQICLPLYKAITKVSSYLSPLLAGCLENREHW 895
BLAST of Phosphodiesterase vs. Planmine SMEST
Match: SMESG000044149.1 (SMESG000044149.1) HSP 1 Score: 261.151 bits (666), Expect = 1.698e-75 Identity = 178/572 (31.12%), Postives = 287/572 (50.17%), Query Frame = 3
Query: 300 EFLLYAYKLPTIISCSRDFYPMDLHL-NQFTQCCVKGLYNATLFETYSSEFSRNKVLLESLHELYEEQNSLEKFMKKSVHKMKEIIKCEEVAVFLLDVCAE----KPSNFGFHCTLNTENKFSLTSEKIGSRKIAKMVCINGESFKCK---SEEK----LDELKEIGISSMICKPIWDSSNHVIGAAQVINKLERDFSKNDEDIMEAITIFCTVGITNCRLYEDMTKSNARAQVALEALSYHTTASLTEVHHIMEKPIPSFSTSQLGSHKFNDFSLSNEEMVLATVKLFIDLKILTLFTIKQETLYKWVITVMKNYRNVAYHNWCHAFNVFHMMIYILHKKSVTQVLLDIEILGLIVGCLCHDLDHRGTNNNFQIKTDSPLAQLYGNQATLEQHHFNLTVMIMNNDGNNIFESLTTDQYSTLMSIIKQSILATDLSNHFKTREKFFSEVENQNCDWRSAEQRKLLRDAL-MTSCDLAAATKQWPVAQKAAILVMEEFFQQGDVEKNIYKIQPQHMMDRSCQDELPEIQIQWITSVCEPLFRHLTMVDKQFQEMYDQLMENVVHWTELKSKPE 1976
E AYK P F P D + N + +Y + T + NK +L +L+ + +++ +K+ + K ++K E V++FLLD ++ K + G T E K ++ K+G +A V G++ + S+E+ +D + +++C P+ +IG Q++NK +F+ DE +C + + ++YE + +S + +VA++ LSYH S+ E + +P F L F +++ N+ + + +F DL L LF E L ++V+TV KNYR V YHNW HAF+V H M +L K+ E L L +G LCHDLDHRG N F ++T PL+ LY +T+E HHFN+T+ I+ DG+NIF L+ Y ++ IK ILATDL+ F+ R+ + N +LL AL MT CDL + K W + +++M EF+ QGD EK+I ++ P +MDR + ELPE Q+ +++ VC P +R L+ + + + + N+ WT L PE
Sbjct: 332 ELYRLAYKYP--------FSPKDEEIFNNYCTWAGLAIYYNEINLTNQKQEKLNKFILNVTQKLFGKFRNVDSIIKEIMASAKSLVKAERVSLFLLDKDSKELYAKIFDKGNFSTCIFETKSTMIRFKVG-EGVAGKVAETGQTLNIRDAYSDERFNRSIDVITGYITKTILCMPV-KMKKEIIGVVQMLNKKNGEFTHKDESDFATFATYCGLALHISKMYEKILRSQQKYKVAIDVLSYHNGYSVEEFEKLKFATVPGF-IKNLDKLSFWPWTVPNDSQPVYVLYMFKDLFGLELF--DAEILMRFVLTVKKNYRKVPYHNWNHAFSVAHAMYSLL--KTCKHRFTLYEALALFIGSLCHDLDHRGKTNQFIMQTSGPLSALYST-STMEHHHFNMTITILQKDGHNIFSHLSPQNYKKVLGHIKHCILATDLAKFFEYRQVI---EKTPNYTNNKINSNRLLHMALSMTFCDLCSMFKSWDMQLTLVMIIMREFWTQGDEEKSIGQL-PIRLMDRDYKLELPEGQVGFLSCVCLPCYRMLSNIMPESGVIIAEAENNLKQWTYLAGLPE 883 The following BLAST results are available for this feature:
BLAST of Phosphodiesterase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Phosphodiesterase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Phosphodiesterase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Phosphodiesterase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Phosphodiesterase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Phosphodiesterase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30026857 ID=SMED30026857|Name=Phosphodiesterase|organism=Schmidtea mediterranea sexual|type=transcript|length=2085bpback to top protein sequence of SMED30026857-orf-1 >SMED30026857-orf-1 ID=SMED30026857-orf-1|Name=SMED30026857-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=574bp MLLQIFQYRMNYEFLLYAYKLPTIISCSRDFYPMDLHLNQFTQCCVKGLYback to top Annotated Terms
The following terms have been associated with this transcript:
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