Protein MAK16 homolog

Overview
NameProtein MAK16 homolog
Smed IDSMED30026844
Length (bp)904
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Protein MAK16 homolog (SMED30026844) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein MAK16 homolog (SMED30026844) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein MAK16 homolog (SMED30026844) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein MAK16 homolog (SMED30026844) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30026844

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30026844SMESG000060104.1 dd_Smed_v4_1416_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30026844SMESG000060104.1 dd_Smed_v4_1416_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30026844SMESG000060104.1 dd_Smed_v4_1416_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30026844SMESG000060104.1 dd_Smed_v4_1416_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30026844SMESG000060104.1 dd_Smed_v4_1416_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30026844SMESG000060104.1 dd_Smed_v4_1416_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30026844SMESG000060104.1 dd_Smed_v4_1416_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30026844SMESG000060104.1 dd_Smed_v4_1416_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026844SMESG000060104.1 Contig54322newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026844SMESG000060104.1 Contig54322uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Category 2 cellSMED30026844SMESG000060104.1 dd_Smed_v6_1416_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Human
Match: MAK16 (MAK16 homolog [Source:HGNC Symbol;Acc:HGNC:13703])

HSP 1 Score: 157.532 bits (397), Expect = 1.469e-45
Identity = 85/170 (50.00%), Postives = 117/170 (68.82%), Query Frame = 2 
Query:   86 MSTGDVVWDIIK-RSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M + DV+WD +  +  CSF  +TKTQ FC+NEY+LTGLCNR+ CPLAN +YAT+KE+    YLY++  ER ++P + WER++L +N ++A EQI+ +LIYWP  I  K K RF  +   + R R + L   + L+  S+KVER E RRE KAL AA L+ +IE EL+ERL
Sbjct:    1 MQSDDVIWDTLGNKQFCSFKIRTKTQSFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQCYLYMKVIERAAFPRRLWERVRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERL 170
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Human
Match: MAK16 (MAK16 homolog [Source:HGNC Symbol;Acc:HGNC:13703])

HSP 1 Score: 136.346 bits (342), Expect = 2.552e-39
Identity = 63/133 (47.37%), Postives = 89/133 (66.92%), Query Frame = 2 
Query:   83 NMSTGDVVWDIIK-RSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTK 478
             M + DV+WD +  +  CSF  +TKTQ FC+NEY+LTGLCNR+ CPLAN +YAT+KE+    YLY++  ER ++P + WER++L +N ++A EQI+ +LIYWP  I  K K RF  +   + R R + L   K
Sbjct:    3 TMQSDDVIWDTLGNKQFCSFKIRTKTQSFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQCYLYMKVIERAAFPRRLWERVRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQK 135
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Celegans
Match: C16A3.6 (pep chromosome:WBcel235:III:6379449:6380671:1 gene:WBGene00015811.1 transcript:C16A3.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C16A3.6)

HSP 1 Score: 137.502 bits (345), Expect = 3.750e-38
Identity = 81/192 (42.19%), Postives = 118/192 (61.46%), Query Frame = 2 
Query:   86 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIAL-NTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKK--NGVANLNKIQFDNFLKD 652
            M   DV W+I+ +  C++   TK + FCKNE NLTGLCNR  CPLAN +YATV+E++ + YLY +  ER  YP + WE+ KL +++++A EQI+  L++W  ++  K K R   +   + R R +A+    K LI   +KVER E RRE KAL AA L+ +IE EL+ RL +     V N  +  F+  L++
Sbjct:    1 MQCDDVTWNILNKGQCAYKAWTKPKMFCKNEMNLTGLCNRASCPLANSQYATVREENGVCYLYAKVVERSHYPRRLWEKTKLSKDMNKALEQISDQLLHWSEYVRHKCKARLIRIHQYLIRMRKMAVRGNQKKLIPIGRKVERREKRREEKALVAAKLDHAIEKELLARLKQGTYGDVYNFRQEAFEQMLEN 192
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Fly
Match: Rbm13 (gene:FBgn0030067 transcript:FBtr0071255)

HSP 1 Score: 165.622 bits (418), Expect = 1.486e-48
Identity = 91/191 (47.64%), Postives = 124/191 (64.92%), Query Frame = 2 
Query:   86 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNG----VANLNKIQFDNFL 646
            M   DVVW II +S CS   KT T+ FC++EYNLTGLC R  CPLAN +YATV+E+  IIYL+I+ AER   P+K WERIKL  N ++A EQIN +L++WP +++ K K RF  +   + R R + L   K+++  S K+ER E RRE KAL AA ++  IE  L++RL  KNG    + N ++  F+  L
Sbjct:    1 MQHDDVVWSIINKSFCSHKVKTDTRTFCRHEYNLTGLCTRRTCPLANSQYATVREEKGIIYLFIKTAERAHMPSKLWERIKLSRNFEKAIEQINENLVFWPKYMIAKNKQRFLKITQYLIRMRRLKLRRQKLIVPLSTKIERREARREEKALVAAKIDNHIEKALMDRL--KNGTYRDIYNFSQTAFNKAL 189
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Fly
Match: Rbm13 (gene:FBgn0030067 transcript:FBtr0346163)

HSP 1 Score: 165.622 bits (418), Expect = 1.486e-48
Identity = 91/191 (47.64%), Postives = 124/191 (64.92%), Query Frame = 2 
Query:   86 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNG----VANLNKIQFDNFL 646
            M   DVVW II +S CS   KT T+ FC++EYNLTGLC R  CPLAN +YATV+E+  IIYL+I+ AER   P+K WERIKL  N ++A EQIN +L++WP +++ K K RF  +   + R R + L   K+++  S K+ER E RRE KAL AA ++  IE  L++RL  KNG    + N ++  F+  L
Sbjct:    1 MQHDDVVWSIINKSFCSHKVKTDTRTFCRHEYNLTGLCTRRTCPLANSQYATVREEKGIIYLFIKTAERAHMPSKLWERIKLSRNFEKAIEQINENLVFWPKYMIAKNKQRFLKITQYLIRMRRLKLRRQKLIVPLSTKIERREARREEKALVAAKIDNHIEKALMDRL--KNGTYRDIYNFSQTAFNKAL 189
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Zebrafish
Match: mak16 (MAK16 homolog (S. cerevisiae) [Source:NCBI gene;Acc:192312])

HSP 1 Score: 155.992 bits (393), Expect = 9.479e-46
Identity = 85/170 (50.00%), Postives = 117/170 (68.82%), Query Frame = 2 
Query:   86 MSTGDVVWDIIK-RSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M   DV+WD+I  +S CS+  KTKTQQFC+NEYN+TGLCNR+ CPLAN +YAT++E+    +LY++  ER ++P++ WE++KL  N  +A EQI+ +LIYWP  I  K K R   +   + R R + L   + L+  S+KVER E RRE KAL AA LE +IE EL++RL
Sbjct:    1 MQHDDVIWDLIGNKSFCSYKVKTKTQQFCRNEYNITGLCNRSSCPLANSQYATIREEKGQCFLYMKVIERAAFPSRMWEKVKLDRNYAKALEQIDENLIYWPRFIRHKCKQRLTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALIAAQLENAIEKELLDRL 170
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Zebrafish
Match: mak16 (MAK16 homolog (S. cerevisiae) [Source:NCBI gene;Acc:192312])

HSP 1 Score: 156.762 bits (395), Expect = 1.989e-45
Identity = 85/170 (50.00%), Postives = 117/170 (68.82%), Query Frame = 2 
Query:   86 MSTGDVVWDIIK-RSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M   DV+WD+I  +S CS+  KTKTQQFC+NEYN+TGLCNR+ CPLAN +YAT++E+    +LY++  ER ++P++ WE++KL  N  +A EQI+ +LIYWP  I  K K R   +   + R R + L   + L+  S+KVER E RRE KAL AA LE +IE EL++RL
Sbjct:    1 MQHDDVIWDLIGNKSFCSYKVKTKTQQFCRNEYNITGLCNRSSCPLANSQYATIREEKGQCFLYMKVIERAAFPSRMWEKVKLDRNYAKALEQIDENLIYWPRFIRHKCKQRLTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALIAAQLENAIEKELLDRL 170
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Xenopus
Match: mak16 (MAK16 homolog [Source:NCBI gene;Acc:394523])

HSP 1 Score: 167.933 bits (424), Expect = 1.293e-49
Identity = 92/189 (48.68%), Postives = 124/189 (65.61%), Query Frame = 2 
Query:   86 MSTGDVVWDIIK-RSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNGVANLNKIQFDNFLK 649
            M   DV+WD++  +  CSF  KTKTQ FC+NEYN+TGLCNR+ CPLAN +YAT+KE+  I YLY++  ER ++PA+ WER++L +N +QA EQI+  LIYWP  I  K K RF  +   + R R + L   + L+  S+KVER E RRE KAL AA L+ +IE EL+ERL K+    ++       F K
Sbjct:    1 MQHDDVIWDVVGNKQFCSFKIKTKTQNFCRNEYNITGLCNRSACPLANSQYATIKEEKGICYLYMKTIERAAFPARMWERVRLSKNYEQALEQIDESLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALVAAQLDNAIEKELLERL-KQGAYGDIYNFPIQAFDK 188
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Xenopus
Match: mak16 (MAK16 homolog [Source:NCBI gene;Acc:394523])

HSP 1 Score: 152.525 bits (384), Expect = 1.212e-43
Identity = 87/173 (50.29%), Postives = 115/173 (66.47%), Query Frame = 2 
Query:  131 CSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNGVANLNKIQFDNFLK 649
            CSF  KTKTQ FC+NEYN+TGLCNR+ CPLAN +YAT+KE+  I YLY++  ER ++PA+ WER++L +N +QA EQI+  LIYWP  I  K K RF  +   + R R + L   + L+  S+KVER E RRE KAL AA L+ +IE EL+ERL K+    ++       F K
Sbjct:   17 CSFK-KTKTQNFCRNEYNITGLCNRSACPLANSQYATIKEEKGICYLYMKTIERAAFPARMWERVRLSKNYEQALEQIDESLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALVAAQLDNAIEKELLERL-KQGAYGDIYNFPIQAFDK 187
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Xenopus
Match: mak16 (MAK16 homolog [Source:NCBI gene;Acc:394523])

HSP 1 Score: 148.288 bits (373), Expect = 4.322e-42
Identity = 83/168 (49.40%), Postives = 112/168 (66.67%), Query Frame = 2 
Query:  146 KTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNGVANLNKIQFDNFLK 649
            +TKTQ FC+NEYN+TGLCNR+ CPLAN +YAT+KE+  I YLY++  ER ++PA+ WER++L +N +QA EQI+  LIYWP  I  K K RF  +   + R R + L   + L+  S+KVER E RRE KAL AA L+ +IE EL+ERL K+    ++       F K
Sbjct:   25 RTKTQNFCRNEYNITGLCNRSACPLANSQYATIKEEKGICYLYMKTIERAAFPARMWERVRLSKNYEQALEQIDESLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALVAAQLDNAIEKELLERL-KQGAYGDIYNFPIQAFDK 191
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Mouse
Match: Mak16 (MAK16 homolog [Source:MGI Symbol;Acc:MGI:1915170])

HSP 1 Score: 154.066 bits (388), Expect = 2.111e-44
Identity = 84/170 (49.41%), Postives = 117/170 (68.82%), Query Frame = 2 
Query:   86 MSTGDVVWDIIK-RSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M + DV+W+ +  +  CSF  +TKTQ FC+NEY+LTGLCNR+ CPLAN +YAT+KE+    YLY++  ER ++P + WER++L +N ++A EQI+ +LIYWP  I  K K RF  +   + R R + L   + L+  S+KVER E RRE KAL AA L+ +IE EL+ERL
Sbjct:    1 MQSDDVIWNTLGNKQFCSFKIRTKTQGFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQCYLYMKVIERAAFPRRLWERVRLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSKKVERREKRREEKALIAAQLDNAIEKELLERL 170
[Close]
BLAST of Protein MAK16 homolog vs. UniProt/SwissProt
Match: sp|P46435|MAK16_SCHMA (Protein MAK16 homolog OS=Schistosoma mansoni OX=6183 GN=MAK16 PE=1 SV=2)

HSP 1 Score: 187.578 bits (475), Expect = 4.713e-57
Identity = 91/191 (47.64%), Postives = 129/191 (67.54%), Query Frame = 2 
Query:   86 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL---VKKNGVANLNKIQFDNFLK 649
            M+  DV+W  I  S CSF+ KTKT +FC+N+ N+TGLCNR  CPLAN +YAT+KE+D IIYL+++E ER+ YP K WERIKL+ N DQA +QI  HL+YW   I+ +VK RF   +  +K  R +AL+  K L   ++ VE+ E RRE KAL+ A +E+++E EL+ERL        + N+++  F+  L+
Sbjct:    1 MNNDDVIWHTINHSFCSFVVKTKTGRFCRNDDNVTGLCNRHSCPLANSQYATIKERDGIIYLFVKEPERIPYPGKQWERIKLRRNKDQALKQIKEHLLYWDKWIISRVKQRFFRTREYLKNMRRLALSRQKKLEPINRTVEKRELRREAKALRVARIERTVEQELLERLRASTSSKEIYNIDQSAFEKALE 191
[Close]
BLAST of Protein MAK16 homolog vs. UniProt/SwissProt
Match: sp|Q66L33|MK16A_XENLA (Protein MAK16 homolog A OS=Xenopus laevis OX=8355 GN=mak16-a PE=2 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 6.321e-49
Identity = 89/170 (52.35%), Postives = 119/170 (70.00%), Query Frame = 2 
Query:   86 MSTGDVVWDIIK-RSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M   DV+WD++  +  CSF  KTKTQ FC+NEYN+TGLCNR+ CPLAN +YAT+KE+  I YLY++  ER ++PA+ WER++L +N +QA EQI+ +LIYWP  I  K K RF  +   + R R + L   + L+  S+KVER E RRE KAL AA L+ +IE EL+ERL
Sbjct:    1 MQHDDVIWDVVGNKQFCSFKIKTKTQNFCRNEYNITGLCNRSACPLANSQYATIKEEKGICYLYMKTIERAAFPARMWERVRLSKNYEQALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALVAAQLDNAIEKELLERL 170
[Close]
BLAST of Protein MAK16 homolog vs. UniProt/SwissProt
Match: sp|Q6P7N1|MAK16_XENTR (Protein MAK16 homolog OS=Xenopus tropicalis OX=8364 GN=mak16 PE=2 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 6.851e-49
Identity = 92/189 (48.68%), Postives = 124/189 (65.61%), Query Frame = 2 
Query:   86 MSTGDVVWDIIK-RSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNGVANLNKIQFDNFLK 649
            M   DV+WD++  +  CSF  KTKTQ FC+NEYN+TGLCNR+ CPLAN +YAT+KE+  I YLY++  ER ++PA+ WER++L +N +QA EQI+  LIYWP  I  K K RF  +   + R R + L   + L+  S+KVER E RRE KAL AA L+ +IE EL+ERL K+    ++       F K
Sbjct:    1 MQHDDVIWDVVGNKQFCSFKIKTKTQNFCRNEYNITGLCNRSACPLANSQYATIKEEKGICYLYMKTIERAAFPARMWERVRLSKNYEQALEQIDESLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALVAAQLDNAIEKELLERL-KQGAYGDIYNFPIQAFDK 188
[Close]
BLAST of Protein MAK16 homolog vs. UniProt/SwissProt
Match: sp|Q7ZYG5|MK16B_XENLA (Protein MAK16 homolog B OS=Xenopus laevis OX=8355 GN=mak16-b PE=2 SV=1)

HSP 1 Score: 166.777 bits (421), Expect = 2.316e-48
Identity = 88/170 (51.76%), Postives = 119/170 (70.00%), Query Frame = 2 
Query:   86 MSTGDVVWDIIK-RSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M   DV+WD++  +  CSF  KTKTQ FC+NE+N+TGLCNR+ CPLAN +YAT+KE+  I YLY++  ER ++PA+ WER++L +N +QA EQI+ +LIYWP  I  K K RF  +   + R R + L   + L+  S+KVER E RRE KAL AA L+ +IE EL+ERL
Sbjct:    1 MQHDDVIWDVVGNKQFCSFKIKTKTQNFCRNEFNITGLCNRSACPLANSQYATIKEEKGICYLYMKTIERAAFPARMWERVRLSKNYEQALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALVAAQLDNAIEKELLERL 170
[Close]
BLAST of Protein MAK16 homolog vs. UniProt/SwissProt
Match: sp|Q9UTE6|MAK16_SCHPO (Protein mak16 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mak16 PE=3 SV=1)

HSP 1 Score: 163.696 bits (413), Expect = 3.501e-47
Identity = 80/175 (45.71%), Postives = 110/175 (62.86%), Query Frame = 2 
Query:   86 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNGV 610
            M   +V+W ++    CS+  K + Q FC+NEYN+TGLCNR  CPLAN RYATV+E +  +YLY++  ER  +P+K W+RIKL +N  +A EQI++ L+YWP   + + K R   L   + + R +AL     LI    K    E  RE KAL AA LEK+IE EL++RL  K+GV
Sbjct:    1 MQQDEVIWQVVGHEFCSYRIKGEAQNFCRNEYNVTGLCNRQSCPLANSRYATVREDNGKLYLYMKTIERAHFPSKLWQRIKLSKNYAKALEQIDQQLLYWPGRQIHRCKQRLTRLTQYLLKARRLALKHQPALIPIKPKQAHREASRERKALIAAKLEKNIEKELVKRL--KSGV 173
[Close]
BLAST of Protein MAK16 homolog vs. TrEMBL
Match: A0A074Z6K5 (Protein MAK16 homolog OS=Opisthorchis viverrini OX=6198 GN=T265_09154 PE=3 SV=1)

HSP 1 Score: 199.134 bits (505), Expect = 2.013e-58
Identity = 96/187 (51.34%), Postives = 133/187 (71.12%), Query Frame = 2 
Query:   32 IFINYLFKYSQINLAIHNMSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            IF ++  + S ++L    M+  DV+W II R+ CSF+ KTKT +FC+N+ N+TGLCNR  CPLAN +YATVKEKD IIYL+++E ER+ YP K WER+KL  N  QA EQINRH+IYW   I+ +VK RF  ++  +K  R +AL+  K L   ++K+ER E RRE KAL+ A +E+++E +L+ERL
Sbjct:   33 IFPSHPAEGSLLDLHGFIMNNDDVIWQIINRAFCSFVVKTKTGKFCRNDNNVTGLCNRHSCPLANSQYATVKEKDGIIYLFLKEPERVPYPGKQWERVKLSRNKKQALEQINRHMIYWDKWIISRVKQRFFRIRDNLKNMRRLALSRQKKLEPVNRKLERREARREKKALRVARVERTVEQKLLERL 219
[Close]
BLAST of Protein MAK16 homolog vs. TrEMBL
Match: A0A1S8WSG8 (Mak16 protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_06746 PE=4 SV=1)

HSP 1 Score: 195.667 bits (496), Expect = 2.688e-58
Identity = 92/169 (54.44%), Postives = 124/169 (73.37%), Query Frame = 2 
Query:   86 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M+  DV+W II R+ CSF+ KTKT +FC+N+ N+TGLCNR  CPLAN +YATVKEKD IIYL+++E ER+ YP K WER+KL  N  QA EQINRH+IYW   I+ +VK RF  ++  +K  R +AL+  K L   ++K+ER E RRE KAL+ A +E+++E +L+ERL
Sbjct:    1 MNNDDVIWQIINRAFCSFVVKTKTGKFCRNDNNVTGLCNRHSCPLANSQYATVKEKDGIIYLFLKEPERVPYPGKQWERVKLSRNKKQALEQINRHMIYWDKWIISRVKQRFFRIRDNLKNMRRLALSRQKKLEPVNRKLERREARREKKALRVARVERTVEQKLLERL 169
[Close]
BLAST of Protein MAK16 homolog vs. TrEMBL
Match: A0A3R7DJV1 (Protein MAK16 homolog OS=Clonorchis sinensis OX=79923 GN=MAK16 PE=3 SV=1)

HSP 1 Score: 195.667 bits (496), Expect = 1.060e-57
Identity = 92/169 (54.44%), Postives = 124/169 (73.37%), Query Frame = 2 
Query:   86 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M+  DV+W II R+ CSF+ KTKT +FC+N+ N+TGLCNR  CPLAN +YATVKEKD IIYL+++E ER+ YP K WER+KL  N  QA EQINRH+IYW   I+ +VK RF  ++  +K  R +AL+  K L   ++K+ER E RRE KAL+ A +E+++E +L+ERL
Sbjct:    1 MNNDDVIWQIINRAFCSFVVKTKTGKFCRNDNNVTGLCNRHSCPLANSQYATVKEKDGIIYLFLKEPERVPYPGKQWERVKLSRNKKQALEQINRHMIYWDKWIISRVKQRFFRIRDNLKNMRRLALSRQKKLEPINRKLERREARREKKALRVARVERTVEQKLLERL 169
[Close]
BLAST of Protein MAK16 homolog vs. TrEMBL
Match: A0A4V3SH50 (Protein MAK16 homolog OS=Opisthorchis felineus OX=147828 GN=CRM22_000701 PE=3 SV=1)

HSP 1 Score: 195.667 bits (496), Expect = 1.233e-57
Identity = 92/169 (54.44%), Postives = 124/169 (73.37%), Query Frame = 2 
Query:   86 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M+  DV+W II R+ CSF+ KTKT +FC+N+ N+TGLCNR  CPLAN +YATVKEKD IIYL+++E ER+ YP K WER+KL  N  QA EQINRH+IYW   I+ +VK RF  ++  +K  R +AL+  K L   ++K+ER E RRE KAL+ A +E+++E +L+ERL
Sbjct:    1 MNNDDVIWQIINRAFCSFVVKTKTGKFCRNDNNVTGLCNRHSCPLANSQYATVKEKDGIIYLFLKEPERVPYPGKQWERVKLSRNKKQALEQINRHMIYWDKWIVSRVKQRFFRIRDNLKNMRRLALSRQKKLEPINRKLERREARREKKALRVARVERTVEQKLLERL 169
[Close]
BLAST of Protein MAK16 homolog vs. TrEMBL
Match: H2KQA6 (Protein MAK16 homolog OS=Clonorchis sinensis OX=79923 GN=CLF_103568 PE=3 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 3.055e-57
Identity = 92/169 (54.44%), Postives = 124/169 (73.37%), Query Frame = 2 
Query:   86 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M+  DV+W II R+ CSF+ KTKT +FC+N+ N+TGLCNR  CPLAN +YATVKEKD IIYL+++E ER+ YP K WER+KL  N  QA EQINRH+IYW   I+ +VK RF  ++  +K  R +AL+  K L   ++K+ER E RRE KAL+ A +E+++E +L+ERL
Sbjct:    1 MNNDDVIWQIINRAFCSFVVKTKTGKFCRNDNNVTGLCNRHSCPLANSQYATVKEKDGIIYLFLKEPERVPYPGKQWERVKLSLNKKQALEQINRHMIYWDKWIISRVKQRFFRIRDNLKNMRRLALSRQKKLEPINRKLERREARREKKALRVARVERTVEQKLLERL 169
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Cavefish
Match: mak16 (MAK16 homolog [Source:NCBI gene;Acc:103045956])

HSP 1 Score: 151.369 bits (381), Expect = 2.007e-43
Identity = 81/170 (47.65%), Postives = 116/170 (68.24%), Query Frame = 2 
Query:   86 MSTGDVVWDII-KRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M   DV+WD+I  +  CS+  KTKT  FC+NEYN+TG CNR  CPLAN +YAT++E+    +LY++  ER ++PA+ WE++KL +N ++A ++I+ +LIYWP +I  K K RF  +   + R R + L   + L+  S+KVER E RRE KAL AA L+ +IE EL+ERL
Sbjct:    1 MQHDDVIWDLIGPKQFCSYKVKTKTGHFCRNEYNITGTCNRQSCPLANSQYATIREEKGQCFLYMKVIERAAFPARMWEKVKLSKNYEKALQEIDENLIYWPFYIRHKCKQRFTKITQYLIRIRKLTLKRQRKLVPLSRKVERREKRREEKALIAAQLDNAIEKELLERL 170
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Yeast
Match: MAK16 (Essential nuclear protein; constituent of 66S pre-ribosomal particles; required for maturation of 25S and 5.8S rRNAs; required for maintenance of M1 satellite double-stranded RNA of the L-A virus [Source:SGD;Acc:S000000023])

HSP 1 Score: 149.443 bits (376), Expect = 1.486e-43
Identity = 81/184 (44.02%), Postives = 111/184 (60.33%), Query Frame = 2 
Query:   92 TGDVVWDIIKRSHCSFMCKTK-TQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIAL-NTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNGVANLNKIQFD 637
            + ++VW +I +S CS   K    Q FC+NEYN+TGLC R  CPLAN +YATVK  +  +YLY++  ER   PAK WERIKL +N  +A +QI+ HL++W      K K RF  L  V+   R +AL    +  +  + KV+R E  RE KAL AA +EK+IE EL++RL  K+G      +  D
Sbjct:    2 SDEIVWQVINQSFCSHRIKAPNGQNFCRNEYNVTGLCTRQSCPLANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERIKLSKNYTKALQQIDEHLLHWSKFFRHKCKQRFTKLTQVMITERRLALREEERHYVGVAPKVKRREQNRERKALVAAKIEKAIEKELMDRL--KSGAYGDKPLNVD 183
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Nematostella
Match: EDO35935 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SK20])

HSP 1 Score: 137.117 bits (344), Expect = 1.510e-40
Identity = 62/124 (50.00%), Postives = 85/124 (68.55%), Query Frame = 2 
Query:  101 VVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNT 472
            ++W +I +  CS+  KT+T+ FC+NEYN TGLCNR  CPLAN RYATV+E D + YLYI+  ER   PA+ WE+IKL +N ++A EQI++HL+YWP   + K K R+  +   I R R + L T
Sbjct:    1 MIWQVINQGFCSYKTKTETKTFCRNEYNSTGLCNRQSCPLANSRYATVREHDGVCYLYIKTIERAHSPAQLWEKIKLNKNYEKALEQIDKHLLYWPNFSIHKCKQRYTKIVQYIIRMRKLRLKT 124
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Medaka
Match: mak16 (MAK16 homolog [Source:NCBI gene;Acc:101167337])

HSP 1 Score: 172.94 bits (437), Expect = 6.899e-52
Identity = 82/170 (48.24%), Postives = 118/170 (69.41%), Query Frame = 2 
Query:   86 MSTGDVVWDIIK-RSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            M   DV+WDII  +  CSF  KTK+Q FC+NE+N+TGLCNR+ CPL+N +YAT++E+    +LY++  ER ++PA+ WE++KL +N ++A EQI+++LIYWP  I  K K RF  +   + R R + L   + L+  S+KVE  E R+E KAL AA L+ +IE EL+ERL
Sbjct:    1 MQHDDVIWDIIGNKQFCSFKVKTKSQNFCRNEFNITGLCNRSSCPLSNSQYATIREEKGQCFLYMKVIERAAFPARMWEKVKLSKNYEKALEQIDQNLIYWPRFIRHKCKQRFTKITQYLIRMRKLVLKRQRKLVPLSRKVESREKRKEEKALIAAQLDNAIEKELLERL 170
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Medaka
Match: mak16 (MAK16 homolog [Source:NCBI gene;Acc:101167337])

HSP 1 Score: 152.14 bits (383), Expect = 2.603e-43
Identity = 71/148 (47.97%), Postives = 105/148 (70.95%), Query Frame = 2 
Query:  149 TKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            TK+Q FC+NE+N+TGLCNR+ CPL+N +YAT++E+    +LY++  ER ++PA+ WE++KL +N ++A EQI+++LIYWP  I  K K RF  +   + R R + L   + L+  S+KVE  E R+E KAL AA L+ +IE EL+ERL
Sbjct:   65 TKSQNFCRNEFNITGLCNRSSCPLSNSQYATIREEKGQCFLYMKVIERAAFPARMWEKVKLSKNYEKALEQIDQNLIYWPRFIRHKCKQRFTKITQYLIRMRKLVLKRQRKLVPLSRKVESREKRKEEKALIAAQLDNAIEKELLERL 212
[Close]
BLAST of Protein MAK16 homolog vs. Ensembl Medaka
Match: mak16 (MAK16 homolog [Source:NCBI gene;Acc:101167337])

HSP 1 Score: 77.411 bits (189), Expect = 7.611e-16
Identity = 42/97 (43.30%), Postives = 60/97 (61.86%), Query Frame = 2 
Query:  302 PAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERL 592
            P     ++KL +N ++A EQI+++LIYWP  I  K K RF  +   + R R + L   + L+  S+KVE  E R+E KAL AA L+ +IE EL+ERL
Sbjct:  111 PPSGRRKVKLSKNYEKALEQIDQNLIYWPRFIRHKCKQRFTKITQYLIRMRKLVLKRQRKLVPLSRKVESREKRKEEKALIAAQLDNAIEKELLERL 207
[Close]
BLAST of Protein MAK16 homolog vs. Planmine SMEST
Match: SMESG000060104.1 (SMESG000060104.1)

HSP 1 Score: 457.603 bits (1176), Expect = 1.906e-164
Identity = 251/251 (100.00%), Postives = 251/251 (100.00%), Query Frame = 2 
Query:   86 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNGVANLNKIQFDNFLKDNRVXXXXXXXXXXXXXGNSDEEQTEFVEAXXXXXXXXXXXLVLKKPILIEQSTSKSRRKIVI 838
            MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNGVANLNKIQFDNFLKDNRVEECDSEAEYEYEDGNSDEEQTEFVEASDIESEEDIEDLVLKKPILIEQSTSKSRRKIVI
Sbjct:    1 MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRYATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYWPAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMKALKAANLEKSIETELIERLVKKNGVANLNKIQFDNFLKDNRVEECDSEAEYEYEDGNSDEEQTEFVEASDIESEEDIEDLVLKKPILIEQSTSKSRRKIVI 251
The following BLAST results are available for this feature:
BLAST of Protein MAK16 homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
MAK161.469e-4550.00MAK16 homolog [Source:HGNC Symbol;Acc:HGNC:13703][more]
MAK162.552e-3947.37MAK16 homolog [Source:HGNC Symbol;Acc:HGNC:13703][more]
back to top
BLAST of Protein MAK16 homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
C16A3.63.750e-3842.19pep chromosome:WBcel235:III:6379449:6380671:1 gene... [more]
back to top
BLAST of Protein MAK16 homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Rbm131.486e-4847.64gene:FBgn0030067 transcript:FBtr0071255[more]
Rbm131.486e-4847.64gene:FBgn0030067 transcript:FBtr0346163[more]
back to top
BLAST of Protein MAK16 homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
mak169.479e-4650.00MAK16 homolog (S. cerevisiae) [Source:NCBI gene;Ac... [more]
mak161.989e-4550.00MAK16 homolog (S. cerevisiae) [Source:NCBI gene;Ac... [more]
back to top
BLAST of Protein MAK16 homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
mak161.293e-4948.68MAK16 homolog [Source:NCBI gene;Acc:394523][more]
mak161.212e-4350.29MAK16 homolog [Source:NCBI gene;Acc:394523][more]
mak164.322e-4249.40MAK16 homolog [Source:NCBI gene;Acc:394523][more]
back to top
BLAST of Protein MAK16 homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Mak162.111e-4449.41MAK16 homolog [Source:MGI Symbol;Acc:MGI:1915170][more]
back to top
BLAST of Protein MAK16 homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P46435|MAK16_SCHMA4.713e-5747.64Protein MAK16 homolog OS=Schistosoma mansoni OX=61... [more]
sp|Q66L33|MK16A_XENLA6.321e-4952.35Protein MAK16 homolog A OS=Xenopus laevis OX=8355 ... [more]
sp|Q6P7N1|MAK16_XENTR6.851e-4948.68Protein MAK16 homolog OS=Xenopus tropicalis OX=836... [more]
sp|Q7ZYG5|MK16B_XENLA2.316e-4851.76Protein MAK16 homolog B OS=Xenopus laevis OX=8355 ... [more]
sp|Q9UTE6|MAK16_SCHPO3.501e-4745.71Protein mak16 OS=Schizosaccharomyces pombe (strain... [more]
back to top
BLAST of Protein MAK16 homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A074Z6K52.013e-5851.34Protein MAK16 homolog OS=Opisthorchis viverrini OX... [more]
A0A1S8WSG82.688e-5854.44Mak16 protein (Fragment) OS=Opisthorchis viverrini... [more]
A0A3R7DJV11.060e-5754.44Protein MAK16 homolog OS=Clonorchis sinensis OX=79... [more]
A0A4V3SH501.233e-5754.44Protein MAK16 homolog OS=Opisthorchis felineus OX=... [more]
H2KQA63.055e-5754.44Protein MAK16 homolog OS=Clonorchis sinensis OX=79... [more]
back to top
BLAST of Protein MAK16 homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mak162.007e-4347.65MAK16 homolog [Source:NCBI gene;Acc:103045956][more]
back to top
BLAST of Protein MAK16 homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Protein MAK16 homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
MAK161.486e-4344.02Essential nuclear protein; constituent of 66S pre-... [more]
back to top
BLAST of Protein MAK16 homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO359351.510e-4050.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Protein MAK16 homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
mak166.899e-5248.24MAK16 homolog [Source:NCBI gene;Acc:101167337][more]
mak162.603e-4347.97MAK16 homolog [Source:NCBI gene;Acc:101167337][more]
mak167.611e-1643.30MAK16 homolog [Source:NCBI gene;Acc:101167337][more]
back to top
BLAST of Protein MAK16 homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000060104.11.906e-164100.00SMESG000060104.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026844 ID=SMED30026844|Name=Protein MAK16 homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=904bp
AAAAGAATAATTTTTATTTTAAAATTTATAAATATTTATTAATTATTTGT
TTAAATATTCACAAATTAATTTGGCGATTCATAATATGAGTACTGGAGAT
GTTGTCTGGGATATTATTAAAAGATCACATTGTAGCTTTATGTGTAAAAC
TAAGACTCAACAATTTTGCAAAAACGAATATAATTTAACAGGTTTATGCA
ATCGAACAGTATGTCCTTTAGCAAATTTCAGATACGCGACAGTTAAGGAG
AAGGATAATATTATCTACTTATATATTAGAGAAGCAGAACGAATGTCATA
TCCAGCAAAACACTGGGAAAGAATAAAATTGAAAGAAAACGTTGATCAAG
CATTTGAGCAAATTAATCGTCATTTAATATATTGGCCGGCGCACATTCTT
AAAAAGGTTAAAACGAGGTTTGCCTGTTTAAAAACTGTTATTAAACGGAG
AAGGAATATTGCTTTAAATACTACTAAAGTTCTTATTGCTAAATCGCAAA
AAGTTGAACGTAATGAAAACCGAAGGGAGATGAAAGCTCTAAAGGCAGCT
AACCTTGAAAAGTCAATAGAAACTGAATTAATTGAACGTTTGGTTAAGAA
AAATGGAGTTGCAAATTTAAATAAAATTCAATTTGACAACTTTTTGAAAG
ACAATCGAGTGGAGGAATGTGATTCAGAAGCTGAATATGAATATGAAGAT
GGCAATTCTGACGAGGAACAAACAGAATTTGTTGAAGCATCAGATATTGA
ATCTGAAGAAGACATAGAAGATTTAGTTCTCAAAAAACCAATTCTGATAG
AACAATCAACTTCTAAAAGTCGCCGCAAGATTGTTATAGAAGAGGATTTA
GATGAAAGTTCTGATTAATAAAAGTTTTTGTTTGAAAAAAAAAGATCGGA
AGAG
back to top

protein sequence of SMED30026844-orf-1

>SMED30026844-orf-1 ID=SMED30026844-orf-1|Name=SMED30026844-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=261bp
MSTGDVVWDIIKRSHCSFMCKTKTQQFCKNEYNLTGLCNRTVCPLANFRY
ATVKEKDNIIYLYIREAERMSYPAKHWERIKLKENVDQAFEQINRHLIYW
PAHILKKVKTRFACLKTVIKRRRNIALNTTKVLIAKSQKVERNENRREMK
ALKAANLEKSIETELIERLVKKNGVANLNKIQFDNFLKDNRVEECDSEAE
YEYEDGNSDEEQTEFVEASDIESEEDIEDLVLKKPILIEQSTSKSRRKIV
IEEDLDESSD*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000028Category 2 cell
PLANA:0000429neoblast
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR006958Mak16
IPR029004L28e/Mak16
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005730nucleolus
Vocabulary: biological process
TermDefinition
GO:0042254ribosome biogenesis
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 135..155
NoneNo IPR availableGENE3DG3DSA:3.30.390.110coord: 3..125
e-value: 1.7E-6
score: 30.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 201..222
NoneNo IPR availablePANTHERPTHR23405:SF4PROTEIN MAK16 HOMOLOGcoord: 1..242
NoneNo IPR availablePANTHERPTHR23405MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATEDcoord: 1..242
IPR029004Ribosomal L28e/Mak16PFAMPF01778Ribosomal_L28ecoord: 6..114
e-value: 1.2E-29
score: 103.4
IPR006958Mak16 proteinPFAMPF04874Mak16coord: 138..229
e-value: 2.0E-15
score: 57.2
IPR006958Mak16 proteinPIRSFPIRSF003352MAK16coord: 1..260
e-value: 1.3E-77
score: 258.6