Histone-lysine N-methyltransferase eggless

Query: 1458 LPAYTTHKC-SRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            LP   ++ C SRV  M N         +Y+  NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL +T C  L L+MF  +  + ++R+FQ  K    I DI+YGKE+V + CVN +D   PP + Y    IP +  F        ++  PEFL+GCDC DGC++KSKC+CHQLT +       G      GY  KRL +  P G++ECN RC C+     NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES
Sbjct:  574 LPHVCSYTCLSRVRPMRNE--------QYRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVF--------INTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYES 872          

Query:  498 NTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYC----KIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF-----KEVVLRPKSKGKRSTMN----KSNKTVVEYTR--TDSKNQLIP 1307
            N + SS +L        S EL       + M +  K     W KG +  I         +K+ V+ +N+   + L+G  +A      DY     K+Y VG+RVV+ Y D N  V  Y+GI+AE P  +N  R+LIFFDDGY  Y  Q+E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQLI+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F         L  K    R+  N    +S   VV+YT+  T +  Q  P
Sbjct:  172 NKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPG---KKYKVKFDNKGKSL-LSGNHIA-----YDYHPPADKLY-VGSRVVAKYKDGNQ-VWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRPNMGAVRSKGPVVQYTQDLTGTGTQFKP 447          

Query: 2697 VKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            V+K   + Y G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CG+ +CRGRLL
Sbjct: 1193 VRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASK-IRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL 1290          

Query: 1458 LPAYTTHKC-SRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            LP   ++ C SRV  M N         +Y+  NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL +T C  L L+MF  +  + ++R+FQ  K    I DI+YGKE+V + CVN +D   PP + Y    IP +  F        ++  PEFL+GCDC DGC++KSKC+CHQLT +       G      GY  KRL +  P G++ECN RC C+     NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES
Sbjct:  574 LPHVCSYTCLSRVRPMRNE--------QYRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVF--------INTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYES 872          

Query:  498 NTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYC----KIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF-----KEVVLRPKSKGKRSTMN----KSNKTVVEYTR--TDSKNQLIP 1307
            N + SS +L        S EL       + M +  K     W KG +  I         +K+ V+ +N+   + L+G  +A      DY     K+Y VG+RVV+ Y D N  V  Y+GI+AE P  +N  R+LIFFDDGY  Y  Q+E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQLI+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F         L  K    R+  N    +S   VV+YT+  T +  Q  P
Sbjct:  172 NKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPG---KKYKVKFDNKGKSL-LSGNHIA-----YDYHPPADKLY-VGSRVVAKYKDGNQ-VWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRPNMGAVRSKGPVVQYTQDLTGTGTQFKP 447          

Query: 2697 VKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            V+K   + Y G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CG+ +CRGRLL
Sbjct: 1193 VRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL 1291          

Query: 1458 LPAYTTHKC-SRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            LP   ++ C SRV  M N         +Y+  NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL +T C  L L+MF  +  + ++R+FQ  K    I DI+YGKE+V + CVN +D   PP + Y    IP +  F        ++  PEFL+GCDC DGC++KSKC+CHQLT +       G      GY  KRL +  P G++ECN RC C+     NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES
Sbjct:  574 LPHVCSYTCLSRVRPMRNE--------QYRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPYKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVF--------INTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYES 872          

Query:  498 NTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYC----KIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF-----KEVVLRPKSKGKRSTMN----KSNKTVVEYTR--TDSKNQLIP 1307
            N + SS +L        S EL       + M +  K     W KG +  I         +K+ V+ +N+   + L+G  +A      DY     K+Y VG+RVV+ Y D N  V  Y+GI+AE P  +N  R+LIFFDDGY  Y  Q+E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQLI+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F         L  K    R+  N    +S   VV+YT+  T +  Q  P
Sbjct:  172 NKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPG---KKYKVKFDNKGKSL-LSGNHIA-----YDYHPPADKLY-VGSRVVAKYKDGNQ-VWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRPNMGAVRSKGPVVQYTQDLTGTGTQFKP 447          

Query:  498 NTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYC----KIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF-----KEVVLRPKSKGKRSTMN----KSNKTVVEYTR--TDSKNQLIP 1307
            N + SS +L        S EL       + M +  K     W KG +  I         +K+ V+ +N+   + L+G  +A      DY     K+Y VG+RVV+ Y D N  V  Y+GI+AE P  +N  R+LIFFDDGY  Y  Q+E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQLI+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F         L  K    R+  N    +S   VV+YT+  T +  Q  P
Sbjct:  172 NKKSSSQDLHKGTLSQMSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGPG---KKYKVKFDNKGKSL-LSGNHIA-----YDYHPPADKLY-VGSRVVAKYKDGNQ-VWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDISCRDFIEEYVTAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASALEKKQGQLRTRPNMGAVRSKGPVVQYTQDLTGTGTQFKP 447          

Query: 1464 AYTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGG-SKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG--------IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFN 2270
            +Y +H CS  C+M             K  NPL++PI   + R  +     S AL     + Y +PCG   RN+ E+ +YL++T+C  L  D FSF   +++ R +   K + +  DIS G E+V I   N +D+   P   Y   +  +    N+ +      F   CDC++GC + +KC+C QLT   ARN +           GY  KRL +  P GI+EC+  C CN Q  +NRVVQ+G   +LQ+FKTE+KGWG+R L DI RG F+CIY+G + +
Sbjct:  129 SYQSHDCSGACLM-------KMPLNLKGENPLQLPIKCHFQRRHAKTNSHSSAL----HVSYKTPCGRSLRNVEEVFRYLLETECNFLFTDNFSFNTYVQLARNYPKQKEVVSDVDISNGVESVPISFCNEIDSRKLPQFKY--RKTVWPRAYNLTNFSS--MFTDSCDCSEGCIDITKCACLQLT---ARNAKTSPLSSDKITTGYKYKRLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQKGWGVRCLDDIDRGTFVCIYSGRLLS 390          

Query:  825 VAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTK----VEKVDASLAYV-------------------NFKNTHR--EWIYRGSTRIE-ALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTDSKNQLIPSNNTKTSARKST-----------SKQKQEPDTNPYVNFNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVM-FNNDPDADDTNRYKCCNPLEIPIHAGWFRIK-SVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIG----------YINKRLYQFHPGGIFE-XXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESK 2357
             A  + ++ +P G   N  Y + F                      +W + +  S  +++ ++ ++PE P+++M +G  I + YNS     K    V   D + A V                   N +N     E IYRGS R+E A  K+ ++   S     +  + ++   ++  TD    +   N+ +   +K+T           +K K+E +      F    I +    ++ L+N      L A+   +C   C+   + DP      R+   +P+  P+  GW RI  +++ G K  A K +I Y SPCG     I ++ +Y+  T+  L +D FSF+  I       V      + D S G E + IP VNSVDND PP ++Y   R  +++ +++  +  D  F  GC C   C + SKC C QL+ E  +   + +           Y N+ L      G++E  +        C NRVVQN +   + IFKT + GWG+R L DIP+  FIC Y G I  ++ A DE +   D+Y A+LD  +T++  K
Sbjct:  596 AAQIAIMVGQPVGKEGNLDYFLTF----------------------HWIRQSHRSA-YIRDFMKEFPEWPLLKMPVGMRICL-YNSLVDRRKKMVTVIGTDRAFAIVRHEAPNPLAPGNRCTDFPCNDRNHQHIDEKIYRGSHRLEGAAHKKHMI---STNNNLSQRRKDQLQSQFEPTDMIRSMPERNHQQVVKKKTTGTNQNVASTNDAKSKREIEIRKKNQFLFNKIIVPIPVLTPLEN------LKAHA--QCGPDCLQKMDADPYE---ARFHRNSPIHTPLLCGWRRIMYTMSTGKKRGAVKKNIIYFSPCGAALHQISDVSEYIHVTRSLLTIDCFSFDARIDTATYITVDDKYLKVADFSLGTEGIPIPLVNSVDNDEPPSLEYSKRRFQYNDQVDISSVSRD--FCSGCSCDGDCSDASKCECQQLSIEAMKRLPHNLQFDGHDELVPHYQNRLLSSKVISGLYECNDQCSCHRKSCYNRVVQNNIKYPMHIFKTAQSGWGVRALTDIPQSTFICTYVGAILTDDLA-DELRN-ADQYFADLDLKDTVELEK 1114          

Query: 2622 AKSSKTGGRRHTSMHVPKVNNDNDTVKK-----FDVREYLGDPNP-FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            +K S  GG        P+ + + D ++      F+  +Y  +P P +++DAK+ GNLGR+ NHSC PN+ VQ+V   +HDLR P VAFF ++ ++AG+E+TWDY Y         L C+CG+ +C GRLL
Sbjct: 1174 SKKSGKGGSVEKDDTTPRDSMEKDNIESKDEPVFNWDKYF-EPFPLYVIDAKQRGNLGRFLNHSCDPNVHVQHVMYDTHDLRLPWVAFFTRKYVKAGDELTWDYQYTQDQTATTQLTCHCGAENCTGRLL 1302          

Query: 2679 NNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRL 2990
            +N   T+K+F    + G P    +D +  GN+GR+ NHSC PN     + +       P    FAKR+I  GEE+ +DY +      ++ L C C S  CR  L
Sbjct:   56 DNYTLTLKEF----FGGKPVKTFVDPRLRGNIGRFLNHSCEPNC---EIILARLGRMIPAAGIFAKRDIVRGEELCYDYGHSAIEGENRKL-CLCKSEKCRKYL 151          

Query: 2721 YLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRG 2984
            YL D   + +DA   GN  R+ NHSC PN   +   +         V FF+KR I+AGEEIT+DY + V    D    C+CGS  C G
Sbjct:  726 YLCDTGVYTIDATVYGNPSRFVNHSCDPNAICEKWSVPRTPGDVNRVGFFSKRFIKAGEEITFDYQF-VNYGRD-AQQCFCGSASCSG 811          

Query: 2721 YLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRG 2984
            YL D   + +DA   GN  R+ NHSC PN   +   +         V FF+KR I+AGEEIT+DY + V    D    C+CGS  C G
Sbjct:  740 YLCDTGVYTIDATVYGNPSRFVNHSCDPNAICEKWSVPRTPGDVNRVGFFSKRFIKAGEEITFDYQF-VNYGRD-AQQCFCGSASCSG 825          

Query: 2742 FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDC 2978
            +++DA  AG   RY NHSC PN   Q +       R  ++   A R I A EE+T+DY + +    DK+  C CG+P+C
Sbjct: 2394 WVIDATMAGGPARYINHSCDPNCSTQ-ILDAGSGAREKKIIITANRPISANEELTYDYQFELEGTTDKI-PCLCGAPNC 2470          

Query:  780 VGTRVVSIY-------SDENGCV--AHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYP-ERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKN--THREWIYRGSTRIEALFKEVVLRP-KSKGKRSTMNKSNKTVVEYTRTDSKNQLIPSNNTKTSARKSTSKQK-------QEPDTNPYVNFNMGDIDL--AGTFISTLDN-----------------ILKTRSLPA--YTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYAR--NHRNG---IGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGV 2378
            +GTRV++ +         + G V  A Y GIIAEP    N YRYLIF+DDGYTQY    +V  V Q + + W+ ++  S++F++ Y++KY  +RPMV+   GQ +  E N  W   +V  +D SL  + F+    H EWIYRGS R+  +F+E       S  ++  + +  +  + YT+    +  + +   +  ARKS++  +           T      N G +    + + +  L+N                     R+LP   Y  H+CS  C+           +R    +PL  P+ +GW R+            K S+ Y  PCG   R++ E+ +YL  T+  LN+D F F  D++   E+ +   I    DIS G+E + IP VN  DN +PP   Y   R   +      HL+ D EFL+ CDC D C +KSKC+C QLT    R  N +     IGY  KRL++  P GI+ECNSRC C   C NRVVQ  L  KLQ+FKT  +GWG+R ++DIP+GAFICIYAG +  E  A + G+  GDEY A+LDYIE  ++ K+GYES V
Sbjct:  532 IGTRVIAYFDGTTLSRGKDKGVVQSAFYPGIIAEPLKQANRYRYLIFYDDGYTQYVPHRDVRLVCQASEKVWEDVHAASRDFIQKYVEKYSVDRPMVQCTRGQSMTTESNGTWLYARVIDIDCSLVLMQFEGDKNHTEWIYRGSLRLGPVFRETQNNMNSSSAQQLRVPRRTEPFIRYTKEMESSSKV-NQQMRAFARKSSASAQNNALAAASSAATPAGGRTNAGGVSTSNSASAVRHLNNSTIYVDDENRPKGHVVYFTAKRNLPPKMYKCHECSPNCLF-------KIVHRLDSYSPLAKPLLSGWERL------VMRQKTKKSVVYKGPCGKSLRSLAEVHRYLRATENVLNVDNFDFTPDLKCLAEYSIDPSIVKDTDISKGQEKMAIPLVNYYDNTLPPPCTYAKQRIPTE----GVHLNLDEEFLLCCDCEDDCSDKSKCACWQLTVAGVRYCNPKKPIEEIGYQYKRLHEHVPTGIYECNSRCKCKKNCLNRVVQFSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLTETMANEGGQDAGDEYFADLDYIEVAEQLKEGYESEV 1092          

Query: 2688 NDTVKKFDVREYLG-DPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            ++TV++  VR   G D  P+IMDAK  GNLGRYFNHSCSPNLFVQNVF+ +HDLR+P VAFF+  +I +G E+TW+Y Y VG VP KVLYC CG+P+CR RLL
Sbjct: 1160 DETVRENSVRRLFGKDEAPYIMDAKTTGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFSAAHIRSGTELTWNYNYEVGVVPGKVLYCQCGAPNCRLRLL 1262          

Query: 2700 KKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDK-VLYCYCGSPDCR 2981
            ++ D   Y    N   +DA   GN+ R+FNHSC PN+    VF +  D R+P++AFF+ R+I+AGEEI +DY  +   V  +  + C C +  C+
Sbjct: 1506 RRTDDSYYFDLDNGHCIDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDYGEKFWRVEHRSCVGCRCLTTTCK 1600          

Query: 1917 NMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTE--KKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELD 2330
            N   +D     +  C C D C +  +C C+  +++   N       +N       P  IFECN  C CN    +NRVVQNG    LQI + E   KGWG+R L ++P+G F+  Y G I    TA++  ++  D Y  +LD
Sbjct: 1384 NSVQIDRRVSQMRICSCLDSCSS-DRCQCNGASSQ---NWYTAESRLNADFNYEDPAVIFECNDVCGCNQLSCKNRVVQNGTRTPLQIVECEDQAKGWGVRALANVPKGTFVGSYTGEIL---TAMEADRRTDDSYYFDLD 1517          

Query: 2700 KKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDK-VLYCYCGSPDCR 2981
            ++ D   Y    N   +DA   GN+ R+FNHSC PN+    VF +  D R+P++AFF+ R+I+AGEEI +DY  +   V  +  + C C +  C+
Sbjct: 1526 RRTDDSYYFDLDNGHCIDANYYGNVTRFFNHSCEPNVLPVRVFYEHQDYRFPKIAFFSCRDIDAGEEICFDYGEKFWRVEHRSCVGCRCLTTTCK 1620          

Query: 1917 NMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTE--KKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELD 2330
            N   +D     +  C C D C +  +C C+  +++   N       +N       P  IFECN  C CN    +NRVVQNG    LQI + E   KGWG+R L ++P+G F+  Y G I    TA++  ++  D Y  +LD
Sbjct: 1404 NSVQIDRRVSQMRICSCLDSCSS-DRCQCNGASSQ---NWYTAESRLNADFNYEDPAVIFECNDVCGCNQLSCKNRVVQNGTRTPLQIVECEDQAKGWGVRALANVPKGTFVGSYTGEIL---TAMEADRRTDDSYYFDLD 1537          

Query: 2745 IMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCR 2981
            ++DA  +G L RY NHSC+PN   + V +   D+R   +  FAKR I  GEE+++DY + +     K+  C CG+P+CR
Sbjct: 2333 VVDATLSGGLARYINHSCNPNCVTEIVEV-DRDVR---IIIFAKRKIYRGEELSYDYKFDIEDESHKI-PCACGAPNCR 2406          

Query: 2745 IMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCR 2981
            ++DA  +G L RY NHSC+PN   + V +   D+R   +  FAKR I  GEE+++DY + +     K+  C CG+P+CR
Sbjct: 2354 VVDATLSGGLARYINHSCNPNCVTEIVEV-DRDVR---IIIFAKRKIYRGEELSYDYKFDIEDESHKI-PCACGAPNCR 2427          

Query: 1467 YTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSS--IYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            Y TH CS  C+     P   + +R +  NPL  P+   + R+     G + L  K S  + Y SPCG   RN+ E+ +YL QT+C  + L+MF  +  + ++R FQ  +    I DI+ G+E++ + CVN +DN  PP + Y   +    ED    +++   +FL+GCDCTDGC++KSKCSCHQLT +       G      GY  KRL +  P GI+ECN RC CN Q   NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES
Sbjct:  612 YLTHNCSPECLK-RIRPTRPNLHRGR--NPLLTPLLYEFRRMT----GRRRLNRKMSFHVIYKSPCGLSLRNMTEIQRYLFQTQCDFIFLEMFCLDPYVLVDRRFQPQRPFYFIRDITSGREDIPLSCVNEIDNTPPPSVAY--SKERIPED--GVYINTSADFLVGCDCTDGCRDKSKCSCHQLTLQATGCTPGGQINPNAGYHYKRLDECLPTGIYECNKRCRCNMQMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYES 911          

Query: 2727 GDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct: 1154 GEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGSTECRGRLL 1242          

Query:  582 ILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLA-SIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF 1196
            I M +  K     W +G +  I    +N+   K+ VR EN+   + L+G  +A     +L+  +++ VG RVV+ Y D N  V  Y+G++AE P ++N  R+LIFFDDGY  Y    E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQ+I+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F
Sbjct:  247 INMTLLGKKRTKTWHRGTLVAIKQVGNNL---KYKVRFENKGKSL-LSGNHVAFEYHPTLE--RLF-VGARVVARYKDGNQ-VWLYAGVVAEMPNSKNRMRFLIFFDDGYASYVGLPELYPICRPLKKTWEDIEDASCRDFIEEYITSYPNRPMVLLKPGQIIKTEWEGTWWKSRVEEVDGSLVKMLFLDDKRSEWIYRGSTRLEPMF 446          

Query: 1467 YTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSS--IYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            Y TH CS  C+     P   + +R +  NPL  P+   + R+     G + L  K S  + Y SPCG   RN+ E+ +YL QT+C  + L+MF  +  + ++R FQ  +    I DI+ G+E++ + CVN +DN  PP + Y   +    ED    +++   +FL+GCDCTDGC++KSKCSCHQLT +       G      GY  KRL +  P GI+ECN RC CN Q   NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES
Sbjct:  584 YLTHNCSPECLK-RIRPTRPNLHRGR--NPLLTPLLYEFRRMT----GRRRLNRKMSFHVIYKSPCGLSLRNMTEIQRYLFQTQCDFIFLEMFCLDPYVLVDRRFQPQRPFYFIRDITSGREDIPLSCVNEIDNTPPPSVAY--SKERIPED--GVYINTSADFLVGCDCTDGCRDKSKCSCHQLTLQATGCTPGGQINPNAGYHYKRLDECLPTGIYECNKRCRCNMQMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYES 883          

Query: 2727 GDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct: 1126 GEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGSTECRGRLL 1214          

Query:  582 ILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLA-SIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF 1196
            I M +  K     W +G +  I    +N+   K+ VR EN+   + L+G  +A     +L+  +++ VG RVV+ Y D N  V  Y+G++AE P ++N  R+LIFFDDGY  Y    E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQ+I+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F
Sbjct:  219 INMTLLGKKRTKTWHRGTLVAIKQVGNNL---KYKVRFENKGKSL-LSGNHVAFEYHPTLE--RLF-VGARVVARYKDGNQ-VWLYAGVVAEMPNSKNRMRFLIFFDDGYASYVGLPELYPICRPLKKTWEDIEDASCRDFIEEYITSYPNRPMVLLKPGQIIKTEWEGTWWKSRVEEVDGSLVKMLFLDDKRSEWIYRGSTRLEPMF 418          

Query: 1551 NPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITN----IPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            NPL IP+   + R+ +       L     I+Y SPCG    ++ E+  YL +T+C  L L+MF  +  + +NR              +PDIS GKE + +PCVN VDN + P + Y    +P R  F        ++   +F++GCDCTDGC+++SKC+CH+LT E       G      GY +KRL    P G++ECN  C C+ +   NR+VQ+G+  +L++F T+ KGWGIR   D+P+G F+C++ G I NE+   ++    G+EY A LD+IE +++ K+GYES
Sbjct:  942 NPLLIPLLFKFRRMTARRRIDGKLF--FHIFYRSPCGRSLCDMQEVQDYLFETRCDFLFLEMFCMDPFVLVNRARPPSTTTGQPHLYLPDISEGKEVMPVPCVNEVDNTLAPNVTYTKDRVPARGVF--------INTSSDFMVGCDCTDGCRDRSKCACHKLTIEATSLCTGGPVDVSAGYTHKRLPTSLPTGVYECNPLCRCDPRMCSNRLVQHGMQLRLELFMTQHKGWGIRCKDDVPKGTFVCVFTGKIVNEDKMNEDDTMSGNEYLANLDFIEGVEKLKEGYES 1220          

Query: 2742 FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            +I+DA++ GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I+AG E+TWDY Y VGSV  KVL C CGS  C GRLL
Sbjct: 1353 YIIDARQEGNLGRYINHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIKAGTELTWDYNYEVGSVEGKVLLCCCGSLRCTGRLL 1436          

Query:  594 VFVKANGDVWLKGVIEGI-TNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQM-NEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKN-THREWIYRGSTRIEALF 1196
            V  K   + W +G ++ + T  D N  + +F      +   I L+   +A+ K      K   +G RVV+    ENG   + +G++ E P  +N  R+L+FFDDG   Y    ++Y V +Q  + W+++ +E S++ VK YL  YP    V +++GQ  +   N ++    V ++D SL  + +KN   +EWIY+GS ++E + 
Sbjct:  580 VLGKKRHNHWSRGTVQEVETEDDGNTYKVEF-----KKGKTIVLSANHVAAYKPP--SLKDLYIGCRVVASAKSENGKSLYNAGVMVELPERKNRMRFLVFFDDGLATYLALPDLYFVCKQTKKVWREIKDESSRKQVKDYLQVYPNPIAVVLRLGQETKAVRNGQFEDCTVLQLDGSLVQICYKNDKQKEWIYKGSDKLEHIL 776          

Query: 1551 NPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITN----IPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            NPL IP+   + R+ +       L     I+Y SPCG    ++ E+  YL +T+C  L L+MF  +  + +NR              +PDIS GKE + +PCVN VDN + P + Y    +P R  F        ++   +F++GCDCTDGC+++SKC+CH+LT E       G      GY +KRL    P G++ECN  C C+ +   NR+VQ+G+  +L++F T+ KGWGIR   D+P+G F+C++ G I NE+   ++    G+EY A LD+IE +++ K+GYES
Sbjct:  942 NPLLIPLLFKFRRMTARRRIDGKLF--FHIFYRSPCGRSLCDMQEVQDYLFETRCDFLFLEMFCMDPFVLVNRARPPSTTTGQPHLYLPDISEGKEVMPVPCVNEVDNTLAPNVTYTKDRVPARGVF--------INTSSDFMVGCDCTDGCRDRSKCACHKLTIEATSLCTGGPVDVSAGYTHKRLPTSLPTGVYECNPLCRCDPRMCSNRLVQHGMQLRLELFMTQHKGWGIRCKDDVPKGTFVCVFTGKIVNEDKMNEDDTMSGNEYLANLDFIEGVEKLKEGYES 1220          

Query: 2742 FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            +I+DA++ GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I+AG E+TWDY Y VGSV  KVL C CGS  C GRLL
Sbjct: 1353 YIIDARQEGNLGRYINHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIKAGTELTWDYNYEVGSVEGKVLLCCCGSLRCTGRLL 1436          

Query:  594 VFVKANGDVWLKGVIEGI-TNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQM-NEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKN-THREWIYRGSTRIEALF 1196
            V  K   + W +G ++ + T  D N  + +F      +   I L+   +A+ K      K   +G RVV+    ENG   + +G++ E P  +N  R+L+FFDDG   Y    ++Y V +Q  + W+++ +E S++ VK YL  YP    V +++GQ  +   N ++    V ++D SL  + +KN   +EWIY+GS ++E + 
Sbjct:  580 VLGKKRHNHWSRGTVQEVETEDDGNTYKVEF-----KKGKTIVLSANHVAAYKPP--SLKDLYIGCRVVASAKSENGKSLYNAGVMVELPERKNRMRFLVFFDDGLATYLALPDLYFVCKQTKKVWREIKDESSRKQVKDYLQVYPNPIAVVLRLGQETKAVRNGQFEDCTVLQLDGSLVQICYKNDKQKEWIYKGSDKLEHIL 776          

Query: 1746 VDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDND-VPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNE--YARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELD 2330
             D R  RE    +++    D+S G E++ +PCVN VD++  P    YIP  + F   +N   +DE+ + L  C C D C + S C C QL+    Y ++     G + K   +  P  +FECN  CSC   CRNRV+QNGL  +LQ+F+TE+ GWG+RTL DIP G F+C +AG I ++  A     +  D Y   LD
Sbjct:   12 TDARRGRESLRERLLCR--DVSRGYEDIPVPCVNGVDHEPCPSNFKYIP-ENCFTSQVN---IDENIKHLQHCSCKDDCASSS-CICGQLSMHCWYGKD-----GRLLKEFCRDDPPFLFECNHACSCWRTCRNRVIQNGLRLRLQVFRTERMGWGVRTLQDIPEGGFVCEFAGEIISDGEA---NIRENDSYMFNLD 194          

Query: 2742 FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCR 2981
            + +D +  GN+ R+ NH C PNLF   VF K  D+R+P +AFFA ++I+AG+E+ +DY      +  K   C CGS  CR
Sbjct:  201 YCIDGQFYGNVSRFMNHLCEPNLFPVRVFTKHQDMRFPRIAFFASKHIQAGDELGFDYGDHYWQIKKKYFRCQCGSGKCR 280          

Query:  780 VGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALFK-----EVVLRPKSKGKRSTMN-----KSNKTVVEYTR--TDSKNQLIPSNNTKTSARK-STSKQKQEPDTNPYV------------NFNMGD------------IDLAGTFISTLD--NILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCC-----------NPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGI------GYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYE 2369
            VG+RVV+ Y D N  V  Y+GI+AEPP N+N  RYLIFFDDGY  Y    E+Y V +  + +W+ + + S ++F++ Y++ YP RPMV +K GQLI+ E+   W  +KVE+VD SL  + F +  R EWIYRGSTR+E +F            K  G++ T       +S   VV+YT   T S+ +  P+       R+   ++   +P   P V            NF   +            I L+   ++++   +I++  ++PA TT+K  +  + +           Y C            NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL + +C+ L L+MF  +  + ++R+FQ  K    IPDI+YGKE+V + CVN +D   PP + Y    IP +  F        ++   E+L+GCDCTDGC++KSKC+CHQLT + A     G       GY +KRL +  P G++ECN RC C++    NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYE
Sbjct:  229 VGSRVVAKYKDGNQ-VWLYAGIVAEPPSNKNKMRYLIFFDDGYASYVTHAELYPVCRPLISSWEDIEDVSCRDFIQEYVNAYPNRPMVLLKSGQLIKTEWEGTWWKSKVEEVDGSLVKILFLDDKRCEWIYRGSTRLEPMFSMKTSTASTQEKKQAGQQRTRPNVGAIRSKGPVVQYTHDLTGSEPEPKPAAPPSPLVREIYKTRSTNKPTLTPIVIMFTVLLWWLSSNFKHHECFYLFNCLIVIWISLSYRIVTSIQQIHIIQAENVPAETTYKAPKEKLFY-----LPHVCNYTCLSRIRPVSHRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLSLRTMPEIERYLFEVECRMLFLEMFCLDPYVLVDRKFQPQKPFYYIPDITYGKEDVPLSCVNEIDRTPPPQVAYSKERIPGKGVF--------INTGAEYLVGCDCTDGCRDKSKCACHQLTIQ-ATGCTPGAQLNPMAGYQHKRLEECLPTGVYECNKRCKCSANMCNNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENYKEGYE 805          

Query: 2496 APKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVG-NVAAKSSKTGGRRHTSMHVPKVN---NDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            A +AT N ++   T+ +   E+E   KN  VA+  G V   VA KS++    + T     K N    +  T ++   + + G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct:  932 AAQATANDSDDIQTISSGSDEEEEK-KN--VATTAGPVKRQVAVKSTRGFALKSTHGITVKTNMASGEGGTGRRNTRQFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKKLLCCCGSTECRGRLL 1098          

Query:  582 ILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYP------VGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALFK-----EVVLRPKSKGKRSTMN-----KSNKTVVEYTR---------------------------TDSKNQLIPSNNTKTSARKSTSKQKQEPDTNPYVNFNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCC-----------NPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYE 2369
            + M +  K     W KG +  I      +A  K+ V+ +N+   + L+G  +A      DY   +P      VG+RVV+ Y D N  V  Y+GI+AEPP N+N  RYLIFFDDGY  Y    E+Y V +  + +W+ + + S ++F++ Y++ YP RPMV +K GQLI+ E+   W  +KVE+VD SL  + F +  R EWIYRGSTR+E +F            K  G++ T       +S   VV+YT                            TDS +Q   S   K  A+KSTS +   P +      +    +                ++PA TT+K  +  + +           Y C            NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL + +C+ L L+MF  +  + ++R+FQ  K    IPDI+YGKE+V + CVN +D   PP + Y    IP +  F        ++   E+L+GCDCTDGC++KSKC+CHQLT +              GY +KRL +  P G++ECN RC C++    NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYE
Sbjct:  162 VGMRILGKKRTKTWHKGTLISI-----QLACYKYKVKFDNKGKSL-LSGNHIA-----YDY---HPPPENLVVGSRVVAKYKDGNQ-VWLYAGIVAEPPSNKNKMRYLIFFDDGYASYVTHAELYPVCRPLISSWEDIEDVSCRDFIQEYVNAYPNRPMVLLKSGQLIKTEWEGTWWKSKVEEVDGSLVKILFLDDKRCEWIYRGSTRLEPMFSMKTSTASTQEKKQAGQQRTRPNVGAIRSKGPVVQYTHDLTGSEPEPKPAAPPSPLSIPSPQLIDTDSDSQQAQSK--KQVAKKSTSFR---PGSAGSGQSSPIPSESVPPPPPPPPPPPVAENVPAETTYKAPKEKLFY-----LPHVCNYTCLSRIRPVSHRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLSLRTMPEIERYLFEVECRMLFLEMFCLDPYVLVDRKFQPQKPFYYIPDITYGKEDVPLSCVNEIDRTPPPQVAYSKERIPGKGVF--------INTGAEYLVGCDCTDGCRDKSKCACHQLTIQATGCTPGAQLNPMAGYQHKRLEECLPTGVYECNKRCKCSANMCNNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENYKEGYE 789          

Query: 2496 APKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVG-NVAAKSSKTGGRRHTSMHVPKVN---NDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            A +AT N ++   T+ +   E+E   KN  VA+  G V   VA KS++    + T     K N    +  T ++   + + G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct:  994 AAQATANDSDDIQTISSGSDEEE-EKKN--VATTAGPVKRQVAVKSTRGFALKSTHGITVKTNMASGEGGTGRRNTRQFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKKLLCCCGSTECRGRLL 1160          

Query:  582 ILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYP------VGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALFK-----EVVLRPKSKGKRSTMN-----KSNKTVVEYTR------------------TDSKNQLIPSNNTKTSARKSTSKQKQEPDTNPYVNFNMGD------IDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCC-----------NPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYE 2369
            + M +  K     W KG +  I      +A  K+ V+ +N+   + L+G  +A      DY   +P      VG+RVV+ Y D N  V  Y+GI+AEPP N+N  RYLIFFDDGY  Y    E+Y V +  + +W+ + + S ++F++ Y++ YP RPMV +K GQLI+ E+   W  +KVE+VD SL  + F +  R EWIYRGSTR+E +F            K  G++ T       +S   VV+YT                   +    QLI   +T + ++++ SK++    +  +   + G          +              ++PA TT+K  +  + +           Y C            NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL + +C+ L L+MF  +  + ++R+FQ  K    IPDI+YGKE+V + CVN +D   PP + Y    IP +  F        ++   E+L+GCDCTDGC++KSKC+CHQLT +              GY +KRL +  P G++ECN RC C++    NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYE
Sbjct:  176 VGMRILGKKRTKTWHKGTLISI-----QLACYKYKVKFDNKGKSL-LSGNHIA-----YDY---HPPPENLVVGSRVVAKYKDGNQ-VWLYAGIVAEPPSNKNKMRYLIFFDDGYASYVTHAELYPVCRPLISSWEDIEDVSCRDFIQEYVNAYPNRPMVLLKSGQLIKTEWEGTWWKSKVEEVDGSLVKILFLDDKRCEWIYRGSTRLEPMFSMKTSTASTQEKKQAGQQRTRPNVGAIRSKGPVVQYTHDLTGSEPEPKPAAPPSPLSIPSPQLI---DTDSDSQQAQSKKQVAKKSTSFRPGSAGSGQSSPIPSESVPPPPPPPPPPPAENVPAETTYKAPKEKLFY-----LPHVCNYTCLSRIRPVSHRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLSLRTMPEIERYLFEVECRMLFLEMFCLDPYVLVDRKFQPQKPFYYIPDITYGKEDVPLSCVNEIDRTPPPQVAYSKERIPGKGVF--------INTGAEYLVGCDCTDGCRDKSKCACHQLTIQATGCTPGAQLNPMAGYQHKRLEECLPTGVYECNKRCKCSANMCNNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENYKEGYE 802          

Query: 2496 APKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVG-NVAAKSSKTGGRRHTSMHVPKVN---NDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            A +AT N ++   T+ +   E+E   KN  VA+  G V   VA KS++    + T     K N    +  T ++   + + G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct: 1018 AAQATANDSDDIQTISSGSDEEEEK-KN--VATTAGPVKRQVAVKSTRGFALKSTHGITVKTNMASGEGGTGRRNTRQFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKKLLCCCGSTECRGRLL 1184          

Query:  582 ILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYP------VGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALFK-----EVVLRPKSKGKRSTMN-----KSNKTVVEYTR------------------TDSKNQLIPSNNTKTSARKSTSKQKQEPDTNPYVNFNMGDIDLAG----TFISTLDNILKT-RSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYY------------VSPCGHRTRNII---------------------------------------ELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG------IGYINKRLYQFHPGGIFE-XXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYE 2369
            + M +  K     W KG +  I         +K+ V+ +N+   + L+G  +A      DY   +P      VG+RVV+ Y D N  V  Y+GI+AEPP N+N  RYLIFFDDGY  Y    E+Y V +  + +W+ + + S ++F++ Y++ YP RPMV +K GQLI+ E+   W  +KVE+VD SL  + F +  R EWIYRGSTR+E +F            K  G++ T       +S   VV+YT                   +    QLI   +T + ++++ SK++    +  +   + G    +     + +S+L +  +  R    +   K S++   F     +  +  +  C    +    G F  ++V   +   APK  ++Y            + P  HR +N +                                       E+++YL + +C+ L L+MF  +  + ++R+FQ  K    IPDI+YGKE+V + CVN +D   PP + Y    IP +  F        ++   E+L+GCDCTDGC++KSKC+CHQLT + A     G       GY +KRL +  P G++E         + C NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYE
Sbjct:  201 VGMRILGKKRTKTWHKGTLISIQCVGPG---KKYKVKFDNKGKSL-LSGNHIA-----YDY---HPPPENLVVGSRVVAKYKDGNQ-VWLYAGIVAEPPSNKNKMRYLIFFDDGYASYVTHAELYPVCRPLISSWEDIEDVSCRDFIQEYVNAYPNRPMVLLKSGQLIKTEWEGTWWKSKVEEVDGSLVKILFLDDKRCEWIYRGSTRLEPMFSMKTSTASTQEKKQAGQQRTRPNVGAIRSKGPVVQYTHDLTGSEPEPKPAAPPSPLSIPSPQLI---DTDSDSQQAQSKKQVAKKSTSFRPGSAGSGQSSPIPSESVLSSLYSPFRIYRPSKPFKAFKPSKLSSQFKPYRLSSLSKPFSLCRQFRLSKETGTFIAENVPAETTYKAPKEKLFYLPHVCNYTCLSRIRPVSHRGKNPLLVPLLYDFRRMTARRRVNRKMGFHVIYKTPCGLSLRTMPEIERYLFEVECRMLFLEMFCLDPYVLVDRKFQPQKPFYYIPDITYGKEDVPLSCVNEIDRTPPPQVAYSKERIPGKGVF--------INTGAEYLVGCDCTDGCRDKSKCACHQLTIQ-ATGCTPGAQLNPMAGYQHKRLEECLPTGVYECNKRCKCSANMCNNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENYKEGYE 875          

Query: 2496 APKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVG-NVAAKSSKTGGRRHTSMHVPKVN--NDNDTVKKFDVREYL-GDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            A +AT N ++   T+ +   E+E   KN  VA+  G V   VA KS++    + T     K N  +      + + R++  G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct: 1096 AAQATANDSDDIQTISSGSDEEE-EKKN--VATTAGPVKRQVAVKSTRGFALKSTHGITVKTNMASGEGGTGRRNTRQFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKKLLCCCGSTECRGRLL 1262          

Query: 1437 NILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCC-----------NPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYE 2369
            +I++  ++PA TT+K  +  + +           Y C            NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL + +C+ L L+MF  +  + ++R+FQ  K    IPDI+YGKE+V + CVN +D   PP + Y    IP +  F        ++   E+L+GCDCTDGC++KSKC+CHQLT +              GY +KRL +  P G++ECN RC C++    NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYE
Sbjct:  590 HIIQAENVPAETTYKAPKEKLFY-----LPHVCNYTCLSRIRPVSHRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLSLRTMPEIERYLFEVECRMLFLEMFCLDPYVLVDRKFQPQKPFYYIPDITYGKEDVPLSCVNEIDRTPPPQVAYSKERIPGKGVF--------INTGAEYLVGCDCTDGCRDKSKCACHQLTIQATGCTPGAQLNPMAGYQHKRLEECLPTGVYECNKRCKCSANMCNNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENYKEGYE 907          

Query: 2496 APKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVG-NVAAKSSKTGGRRHTSMHVPKVN---NDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            A +AT N ++   T+ +   E+E   KN  VA+  G V   VA KS++    + T     K N    +  T ++   + + G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct: 1118 AAQATANDSDDIQTISSGSDEEE-EKKN--VATTAGPVKRQVAVKSTRGFALKSTHGITVKTNMASGEGGTGRRNTRQFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKKLLCCCGSTECRGRLL 1284          

Query:  582 ILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYP------VGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF 1196
            + M +  K     W KG +  I         +K+ V+ +N+   + L+G  +A      DY   +P      VG+RVV+ Y D N  V  Y+GI+AEPP N+N  RYLIFFDDGY  Y    E+Y V +  + +W+ + + S ++F++ Y++ YP RPMV +K GQLI+ E+   W  +KVE+VD SL  + F +  R EWIYRGSTR+E +F
Sbjct:  200 VGMRILGKKRTKTWHKGTLISIQCVGPG---KKYKVKFDNKGKSL-LSGNHIA-----YDY---HPPPENLVVGSRVVAKYKDGNQ-VWLYAGIVAEPPSNKNKMRYLIFFDDGYASYVTHAELYPVCRPLISSWEDIEDVSCRDFIQEYVNAYPNRPMVLLKSGQLIKTEWEGTWWKSKVEEVDGSLVKILFLDDKRCEWIYRGSTRLEPMF 399          

Query: 1467 YTTHKCSRVCV-----MFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGV 2378
            Y  H CS  C+     M N         +Y+  NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL +T C  L L+MF  +  + ++R+FQ  K    I DI+YGKE+V + CVN +D   PP + Y    IP +  F        ++  PEFL+GCDC DGC++KSKC+CHQLT +       G      GY  KRL +  P G++ECN RC+C+     NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES V
Sbjct:  590 YLPHVCSYTCLSRIRPMRNE--------QYRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVF--------INTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQVNPNSGYQYKRLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDV 891          

Query: 2697 VKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            V+K   + Y G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CG+ +CRGRLL
Sbjct: 1209 VRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL 1307          

Query:  498 NTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYC----KIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF-----KEVVLRPKSKGK---RSTMN--KSNKTVVEYTR 1280
            N + SS +L        S EL       + M +  K     W KG +  I         +K+ V+ +N+   + L+G  +A      DY     K++ VG+RVV+ Y D N  V  Y+GI+AE P  +N  R+LIFFDDGY  Y  Q+E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQLI+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F         +  K  G+   R  M   +S   VV+YT+
Sbjct:  172 NKKSSSQDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLG---KKYKVKFDNKGKSL-LSGNHIA-----YDYHPPADKLF-VGSRVVAKYKDGNQ-VWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQ 437          

Query: 1467 YTTHKCSRVCV-----MFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGV 2378
            Y  H CS  C+     M N         +Y+  NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL +T C  L L+MF  +  + ++R+FQ  K    I DI+YGKE+V + CVN +D   PP + Y    IP +  F        ++  PEFL+GCDC DGC++KSKC+CHQLT +       G      GY  KRL +  P G++ECN RC+C+     NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES V
Sbjct:  591 YLPHVCSYTCLSRIRPMRNE--------QYRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVF--------INTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQVNPNSGYQYKRLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDV 892          

Query: 2697 VKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            V+K   + Y G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CG+ +CRGRLL
Sbjct: 1210 VRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL 1308          

Query:  498 NTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYC----KIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF-----KEVVLRPKSKGK---RSTMN--KSNKTVVEYTR 1280
            N + SS +L        S EL       + M +  K     W KG +  I         +K+ V+ +N+   + L+G  +A      DY     K++ VG+RVV+ Y D N  V  Y+GI+AE P  +N  R+LIFFDDGY  Y  Q+E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQLI+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F         +  K  G+   R  M   +S   VV+YT+
Sbjct:  172 NKKSSSQDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLG---KKYKVKFDNKGKSL-LSGNHIA-----YDYHPPADKLF-VGSRVVAKYKDGNQ-VWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQ 437          

Query: 1467 YTTHKCSRVCV-----MFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGV 2378
            Y  H CS  C+     M N         +Y+  NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL +T C  L L+MF  +  + ++R+FQ  K    I DI+YGKE+V + CVN +D   PP + Y    IP +  F        ++  PEFL+GCDC DGC++KSKC+CHQLT +       G      GY  KRL +  P G++ECN RC+C+     NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES V
Sbjct:  591 YLPHVCSYTCLSRIRPMRNE--------QYRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVF--------INTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQVNPNSGYQYKRLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDV 892          

Query: 2697 VKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            V+K   + Y G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CG+ +CRGRLL
Sbjct: 1210 VRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL 1308          

Query:  498 NTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYC----KIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF-----KEVVLRPKSKGK---RSTMN--KSNKTVVEYTR 1280
            N + SS +L        S EL       + M +  K     W KG +  I         +K+ V+ +N+   + L+G  +A      DY     K++ VG+RVV+ Y D N  V  Y+GI+AE P  +N  R+LIFFDDGY  Y  Q+E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQLI+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F         +  K  G+   R  M   +S   VV+YT+
Sbjct:  172 NKKSSSQDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLG---KKYKVKFDNKGKSL-LSGNHIA-----YDYHPPADKLF-VGSRVVAKYKDGNQ-VWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQ 437          

Query: 1239 TMNKSNKTVVEYTRTDSKNQLI----PSNNTKTSARKSTSKQKQEPDTNPYVNFNMGDIDLAGTFIST------------LDNILKTRSLPAYTT---HKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGG-SKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYAR-----NHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEET 2279
             MN  N+  +  T+T  K   I    P  NT  S     ++ +QE  ++   + +  +    G  I +             DN++K +  P + +   H CSR C+M       +     K  NPL++PI   + R  +     S AL     + Y +PCG   RN+ E+  YL++T+C  L  D FSF   +++ R       + +  DIS G E+V IP  N +DN   P   Y     P  +H    LN  ++  D      CDC++GC +  KC+C QLT + A+     +     GY  KRL +  P GI+ECN  C CN Q  +NRV+Q+G+  +LQ+FK+EKKGWG+R L DI +G F+CIY+G +    T
Sbjct:   52 AMNLVNEATLSNTQTLEKGMFITYSNPEVNTHRSNHTPVTQSEQENKSSAVPSASCDNSCPKGCTIPSPGKKVFLPVKNKADNLVK-KEAPLHISFHRHICSRTCLM-------ETPLSLKGENPLQLPIRCHFQRRHAKTNSHSSAL----HVNYKTPCGRNLRNMEEVFHYLLETECNFLFTDNFSFNTYVQLTRNHPKQNEVVSDVDISNGVESVSIPFCNEIDNSKLPRFKYRNTVWPRIYH----LNFSNMFSD-----SCDCSEGCIDIKKCACLQLTAKNAKACPLSSDGECAGYKYKRLQRLIPTGIYECNLLCKCNKQMCQNRVIQHGVRVRLQVFKSEKKGWGVRCLDDIDKGTFVCIYSGRLLRRAT 408          

Query: 2742 FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            F++DA + GN+GR+ NHSC PNL+VQNVF+++HD  +P VAFF  R ++A  E+TWDY Y  G+ P K + C CG   CR +L+
Sbjct:  630 FLLDASKEGNVGRFLNHSCCPNLWVQNVFVETHDRNFPLVAFFTNRYVKARTELTWDYGYEAGATPAKEILCQCGFNKCRKKLI 713          

Query: 1434 DNILKTRSLPAYTT---HKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGG-SKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYAR-----NHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEET 2279
            DN++K +  P + +   H CSR C+M       +     K  NPL++PI   + R  +     S AL     + Y +PCG   RN+ E+  YL++T+C  L  D FSF   +++ R       + +  DIS G E+V IP  N +DN   P   Y     P  +H    LN  ++     F   CDC++GC +  KC+C QLT + A+     +     GY  KRL +  P GI+ECN  C CN Q  +NRV+Q+G+  +LQ+FK+EKKGWG+R L DI +G F+CIY+G +    T
Sbjct:  117 DNLVK-KEAPLHISFHRHICSRTCLM-------ETPLSLKGENPLQLPIRCHFQRRHAKTNSHSSAL----HVNYKTPCGRNLRNMEEVFHYLLETECNFLFTDNFSFNTYVQLTRNHPKQNEVVSDVDISNGVESVSIPFCNEIDNSKLPRFKYRNTVWPRIYH----LNFSNM-----FSDSCDCSEGCIDIKKCACLQLTAKNAKACPLSSDGECAGYKYKRLQRLIPTGIYECNLLCKCNKQMCQNRVIQHGVRVRLQVFKSEKKGWGVRCLDDIDKGTFVCIYSGRLLRRAT 392          

Query: 2724 LGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            L   + F++DA + GN+GR+ NHSC PNL+VQNVF+++HD  +P VAFF  R ++A  E+TWDY Y  G+ P K + C CG   CR +L+
Sbjct:  608 LSKESLFLLDASKEGNVGRFLNHSCCPNLWVQNVFVETHDRNFPLVAFFTNRYVKARTELTWDYGYEAGATPAKEILCQCGFNKCRKKLI 697          

Query:  777 PVGTRVVSIY------SDENGCV--AHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYP-ERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFK--NTHREWIYRGSTRIEALFKEV--VLRPKSKGKRSTMNKSNKTVVEYTRTDSKNQLIPSNNTKTSARKSTSKQ-----KQEPDTNPYVNFNMGDIDLAGTFI-------STLDNILKTRSLPA--YTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYAR--NHRNGI---GYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGV 2378
            P+GTRV++ +        E G V  A Y GIIAEP    N +RYLIF+DDGYTQY   ++V  V Q + + W+ ++  S++F++ Y+++Y  +RPMV+   GQ +  E N  W   +V +VD SL  + F+    H EWIYRGS R+  +FKE    L       +  + +  +  + YT+    + +      +  ARKSTSK         P T    +  +  ++ +  ++         + +    R++P   + +HKC+  C            +R    +PL  P+ +GW R+            K ++ Y  PCG   RN+ E+  YL  T   LN+D F F  D+R   E+ +   I    DIS G+E + IP VN  DN +PP  +Y   R    E +N+ +LDE  EFL+ CDC D C +K  C+C QLT    R  N +  I   GY  KRL++    GI+ECNSRC C   C NRVVQ+ L  KLQ+FKT  +GWG+R ++DIP+GAF+CIYAG +  E  A + G+  GDEY A+LDYIE  ++ K+GYES V
Sbjct:  537 PIGTRVIAFFDGTLVGGKEKGVVQSAFYPGIIAEPLKQNNRFRYLIFYDDGYTQYVHHSDVRLVCQASEKVWEDVHPASRDFIQKYVERYAVDRPMVQCTKGQSMNTESNGTWLYARVIEVDCSLVLMQFEADKNHTEWIYRGSLRLAPVFKETQNSLNADCAIHQMRVPRRTEPFIRYTKEMESSNMQVDQQIRAIARKSTSKSGSPASTAAPPTGSSSSSAVRHLNNSTIYVDDDTRPKGQVVHFTAKRNMPPKIFKSHKCNPGCPF-------PMMHRLDSYSPLSKPLLSGWERM------FMKQKTKRTVVYRGPCGRNLRNMAEVHNYLRLTNNVLNVDNFDFTPDLRCLAEYYIESTIVKEADISKGQEKMAIPLVNYYDNTLPPPCEYAKQRIP-TEGVNL-NLDE--EFLVCCDCEDDCSDKESCACWQLTVTGVRYCNPKKPIEEIGYQYKRLHEGVLTGIYECNSRCKCKKNCLNRVVQHSLEMKLQVFKTSNRGWGLRCVNDIPKGAFVCIYAGHLLTEAKANEGGQDAGDEYFADLDYIEVAEQLKEGYESDV 1085          

Query: 2688 NDTVKKFDVREYLG-DPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            ++TV++  VR + G D  PFIMDAK  GNLGRYFNHSCSPNLFVQNVF+ +HDLR+P V FFA  +I +G E+TW+Y Y VG VP+KVLYC CG+ +CR RLL
Sbjct: 1152 DETVRENSVRRFFGKDQTPFIMDAKTTGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVGFFASSHIRSGTELTWNYNYEVGVVPNKVLYCQCGAQNCRVRLL 1254          

Query:  780 VGTRVVSIY-------SDENGCV--AHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYP-ERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKN--THREWIYRGSTRIEALFKEVVLRP-KSKGKRSTMNKSNKTVVEYTRTDSKNQLIPSNNTKTSARKSTSKQK-------QEPDTNPYVNFNMGDIDL--AGTFISTLDN-----------------ILKTRSLPA--YTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYAR--NHRNG---IGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGV 2378
            +GTRV++ +         + G V  A Y GIIAEP    N YRYLIF+DDGYTQY    +V  V Q + + W+ ++  S++F++ Y++KY  +RPMV+   GQ +  E N  W   +V  +D SL  + F+    H EWIYRGS R+  +F+E       S  ++  + +  +  + YT+    +  + +   +  ARKS++  +           T      N G +    + + +  L+N                     R+LP   Y  H+CS  C+           +R    +PL  P+ +GW R+            K S+ Y  PCG   R++ E+ +YL  T+  LN+D F F  D++   E+ +   I    DIS G+E + IP VN  DN +PP   Y   R   +      HL+ D EFL+ CDC D C +KSKC+C QLT    R  N +     IGY  KRL++  P GI+ECNSRC C   C NRVVQ  L  KLQ+FKT  +GWG+R ++DIP+GAFICIYAG +  E  A + G+  GDEY A+LDYIE  ++ K+GYES V
Sbjct:  532 IGTRVIAYFDGTTLSRGKDKGVVQSAFYPGIIAEPLKQANRYRYLIFYDDGYTQYVPHRDVRLVCQASEKVWEDVHAASRDFIQKYVEKYSVDRPMVQCTRGQSMTTESNGTWLYARVIDIDCSLVLMQFEGDKNHTEWIYRGSLRLGPVFRETQNNMNSSSAQQLRVPRRTEPFIRYTKEMESSSKV-NQQMRAFARKSSASAQNNALAAASSAATPAGGRTNAGGVSTSNSASAVRHLNNSTIYVDDENRPKGHVVYFTAKRNLPPKMYKCHECSPNCLF-------KIVHRLDSYSPLAKPLLSGWERL------VMRQKTKKSVVYKGPCGKSLRSLAEVHRYLRATENVLNVDNFDFTPDLKCLAEYSIDPSIVKDTDISKGQEKMAIPLVNYYDNTLPPPCTYAKQRIPTE----GVHLNLDEEFLLCCDCEDDCSDKSKCACWQLTVAGVRYCNPKKPIEEIGYQYKRLHEHVPTGIYECNSRCKCKKNCLNRVVQFSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLTETMANEGGQDAGDEYFADLDYIEVAEQLKEGYESEV 1092          

Query: 2688 NDTVKKFDVREYLG-DPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            ++TV++  VR   G D  P+IMDAK  GNLGRYFNHSCSPNLFVQNVF+ +HDLR+P VAFF+  +I +G E+TW+Y Y VG VP KVLYC CG+P+CR RLL
Sbjct: 1160 DETVRENSVRRLFGKDEAPYIMDAKTTGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFSAAHIRSGTELTWNYNYEVGVVPGKVLYCQCGAPNCRLRLL 1262          

Query: 1467 YTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSS--IYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            Y TH CS  C+     P   + +R +  NPL  P+   + R+     G + L  K S  + Y SPCG   RN+ E+ +YL QT+C  + L+MF  +  + ++R FQ  +    I DI+ G+E++ + CVN +DN  PP + Y   +    ED    +++   +FL+GCDCTDGC++KSKCSCHQLT +       G      GY  KRL +  P GI+ECN RC CN Q   NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES
Sbjct:  574 YLTHNCSPECLK-RIRPTRPNLHRGR--NPLLTPLLYEFRRMT----GRRRLNRKMSFHVIYKSPCGLSLRNMTEIQRYLFQTQCDFIFLEMFCLDPYVLVDRRFQPQRPFYFIRDITSGREDIPLSCVNEIDNTPPPSVAY--SKERIPED--GVYINTSADFLVGCDCTDGCRDKSKCSCHQLTLQATGCTPGGQINPNAGYHYKRLDECLPTGIYECNKRCRCNMQMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYES 873          

Query: 2727 GDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct: 1116 GEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGSTECRGRLL 1204          

Query:  582 ILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLA-SIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF 1196
            I M +  K     W +G +  I    +N+   K+ VR EN+   + L+G  +A     +L+  +++ VG RVV+ Y D N  V  Y+G++AE P ++N  R+LIFFDDGY  Y    E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQ+I+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F
Sbjct:  209 INMTLLGKKRTKTWHRGTLVAIKQVGNNL---KYKVRFENKGKSL-LSGNHVAFEYHPTLE--RLF-VGARVVARYKDGNQ-VWLYAGVVAEMPNSKNRMRFLIFFDDGYASYVGLPELYPICRPLKKTWEDIEDASCRDFIEEYITSYPNRPMVLLKPGQIIKTEWEGTWWKSRVEEVDGSLVKMLFLDDKRSEWIYRGSTRLEPMF 408          

Query: 1467 YTTHKCSRVCV-----MFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGV 2378
            Y  H CS  C+     M N         +Y+  NPL +P+   + R+ +    ++ +     + Y +PCG   R + E+++YL +T C  L L+MF  +  + ++R+FQ  K    I DI+YGKE+V + CVN +D   PP + Y    IP +  F        ++  PEFL+GCDC DGC++KSKC+CHQLT +       G      GY  KRL +  P G++ECN RC+C+     NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES V
Sbjct:  590 YLPHVCSYTCLSRIRPMRNE--------QYRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKTPCGLCLRTMQEIERYLFETGCDFLFLEMFCLDPYVLVDRKFQPFKPFYYILDITYGKEDVPLSCVNEIDTTPPPQVAYSKERIPGKGVF--------INTGPEFLVGCDCKDGCRDKSKCACHQLTIQATACTPGGQVNPNSGYQYKRLEECLPTGVYECNKRCNCDPNMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYESDV 891          

Query: 2697 VKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            V+K   + Y G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CG+ +CRGRLL
Sbjct: 1209 VRKNTRQFYDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGAIECRGRLL 1307          

Query:  498 NTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYC----KIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF-----KEVVLRPKSKGK---RSTMN--KSNKTVVEYTR 1280
            N + SS +L        S EL       + M +  K     W KG +  I         +K+ V+ +N+   + L+G  +A      DY     K++ VG+RVV+ Y D N  V  Y+GI+AE P  +N  R+LIFFDDGY  Y  Q+E+Y + +   + W+ + + S ++F++ Y+  YP RPMV +K GQLI+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F         +  K  G+   R  M   +S   VV+YT+
Sbjct:  172 NKKSSSQDLHKGTLGQVSGELSKDGDLIVSMRILGKKRTKTWHKGTLIAIQTVGLG---KKYKVKFDNKGKSL-LSGNHIA-----YDYHPPADKLF-VGSRVVAKYKDGNQ-VWLYAGIVAETPNVKNKLRFLIFFDDGYASYVTQSELYPICRPLKKTWEDIEDSSCRDFIEEYITAYPNRPMVLLKSGQLIKTEWEGTWWKSRVEEVDGSLVRILFLDDKRCEWIYRGSTRLEPMFSMKTSSASAMEKKQGGQLRTRPNMGAVRSKGPVVQYTQ 437          

Query: 1437 NILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCC-----------NPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEY-----ARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYE 2369
             I++T ++PA +T+K  +  + +           Y C            NPL +P+   + R+ +    ++ +     + Y SPCG   R + E+++YL +T+CK L L+MF  +  + ++R+FQ  K    IPDI+YGKE+V + CVN +D   PP + Y    IP +  F        ++   ++L+GCDCTDGC++KSKC+CHQLT +              GY +KRL +  P G++ECN RC C++    NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYE
Sbjct:  580 QIIRTENIPAESTYKAPKEKLFY-----LPHVCNYTCLSRIRPLSHRGKNPLLVPLLYDFRRMTARRRVNRKMG--FHVIYKSPCGLSLRTMPEIERYLFETQCKMLFLEMFCLDPYVLVDRKFQPQKPFYYIPDITYGKEDVMLSCVNEIDRTPPPQVAYSKERIPGKGVF--------INTGADYLVGCDCTDGCRDKSKCACHQLTIQATACTPGAQSNPMAGYQHKRLEECLPTGVYECNKRCKCSANMCNNRLVQHGLQVRLQLFKTQNKGWGIRGLDDIAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYE 897          

Query: 2496 APKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVG-NVAAKSSKTGGRRHTSMHVPKVN--NDNDTVKKFDVREYL-GDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            A +AT N ++   T+ +   E+E   KN  VA+  G V   VA KS++    + T     K N  +      + + R++  G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct: 1103 AAQATANDSDDIQTISSGSDEEE-EKKN--VAASAGPVKRQVAVKSTRGFALKSTHGITVKSNMASGEGGPGRRNTRQFFDGEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKKLLCCCGSTECRGRLL 1269          

Query:  582 ILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYP------VGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF 1196
            + M +  K     W KG +  I    +    +KF V+ +N+   + L+G  +A      DY   +P      VG+RVV+ Y D N  V  Y+GI+AEPP ++N  RYLIFFDDGY  Y    E+Y V +   ++W+ + + S ++F++ Y++ YP RPMV +K GQLI+ E+   W  +KVE+VD SL  + F +  R EWIYRGSTR+E +F
Sbjct:  194 VGMRILGKKRTKTWHKGTLISIQCVGTG---KKFKVKFDNKGKSL-LSGNHIA-----YDY---HPPPENLTVGSRVVAKYKDGNQ-VWLYAGIVAEPPSSKNKMRYLIFFDDGYASYVTHAELYPVCRPWSKSWEDIEDVSCRDFIQEYVNAYPNRPMVLLKSGQLIKTEWEGTWWKSKVEEVDGSLVKILFLDDKRCEWIYRGSTRLEPMF 393          

Query:  543 ISSKELLNGFQASILMPVFVKANGDVWLKGVIEG--ITNKDSNIAEQKFDVRLENEDLLINLT---------------GFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHREWIYRGSTRIEALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTD-----------SKNQLIPSNNTKTSAR-----------------------------KSTSKQKQEPDTN-------PYVNFNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMFNNDPDA--------DDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYAR-NHRNGI-----GYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGV 2378
            +   ELL G Q +   PV  +     W  G +    + N D +  +   D   ENE+    +                  SLA   S+ +  + YPVG RVVSIY D+ G + +YSG+IAEPP  RNN RYL+FFDDGYTQYS  NEVY +  Q+ ENWK+  E SQEF+K YL +YP+RPMVR+K GQ +  E + +W    VEKVDASLA + F  TH EWIYRGSTR+E LF +++    S   +S    + +  VEY+  D           ++     + NT  S R                             K+TSK+  E + N       P  N  + +++  GT  S LDN+ K      + +HKC   C+     P +        ++   YK  NPLEIP H GW R   +A     +  K +I Y +PCG   R++ E++++L +T  +L  D+FSF+  + IN+EF+  K +TNI D+SYGKENV IPCVNSVDN+VP YIDY P R    + +    L +D +FL+ CDCTD C++++KC+C QLT E +   + NG+     GY  +RL QF  GG++ECNS C C+ +C NRVVQ GLW +LQ+FKT +KGWGIR L+ IP+G FIC YAG I++E  AV EG   GDEYQAELDYIET+++ K+GYES V
Sbjct:   56 LQPAELLLGLQLTPSQPVLYRKTQHTWFPGRVLSCHLPNSDPSTPKSDKDRAKENENAQYTIALDTSSKSKSEICFAVTSSLALAFSASELRQKYPVGARVVSIYRDDTGGIGYYSGLIAEPPSERNNQRYLLFFDDGYTQYSPPNEVYRICHQSKENWKEATESSQEFIKRYLAQYPQRPMVRLKPGQTVETELDGDWMKATVEKVDASLALMKFSRTHSEWIYRGSTRLEPLFSDLL----SSQSKSVPTHNQRVEVEYSSVDVPLDSSAKRRKARKSATGNQNTAMSVRALSSGDSHKISNSIHQTNKSLSNYNNEALKTTSKKGSEKNINEQCLSIDPITN--LSELESTGTKTSYLDNLFKEFDYKPFESHKCGHYCLKSYRKPSSALSPILCSENPVDYKGLNPLEIPFHCGWLRY--LAKYDPPVNNKCNIIYTAPCGRSLRSMHEVERFLDKTNSQLTADLFSFDSTLIINQEFRAEKTLTNIVDLSYGKENVPIPCVNSVDNEVPGYIDYTPQR----QPIGNVPLLKDSKFLVCCDCTDNCRDRTKCACQQLTVEASSLTNPNGLVDSQAGYRYRRLSQFTVGGVYECNSNCQCDRRCSNRVVQQGLWVRLQVFKTARKGWGIRALNAIPKGTFICTYAGAIYDEAMAVQEGFDCGDEYQAELDYIETVEKDKEGYESTV 733          

Query: 2712 VREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
             R Y  D NP+IMDAK+ GNLGRYFNHSC+PN+FVQNVFI +HD R+PEVAFFAKRNI+ GEE+TWDY Y V +VP KVLYCYCG P+CR RLL
Sbjct:  825 ARTYFNDINPYIMDAKKMGNLGRYFNHSCNPNVFVQNVFIDTHDPRFPEVAFFAKRNIDVGEEMTWDYGYTVDAVPFKVLYCYCGEPNCRIRLL 918          

Query:  543 ISSKELLNGFQASILMPVFVKANGDVWLKGVI----EGITNKDSN----------IAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHREWIYRGSTRIEALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTD-------SKNQLIPSNNTKTSARKS-----------TSKQKQEPDTNPYVN--FNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMF----NNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYAR-NHRNGI-----GYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESG 2375
            +   ELL G   +   PV  +   D W  G I       T+ D N          I     D     +D + + +  SLA   S+ D  + YPVG RVVSIY DE+G + +YSG+IAEPP  RNN+RYL+FFDDGYTQYS  NE+Y +  Q+ ENW++  E SQ+F+K YL +YP+RPMVR+K GQ+I  E + +W    V+KVDASL  + F  TH EWIYRGSTR+E LF ++     S   ++ + +S +  VEY   D       S  +L  +  + T  R S           T+ +++ P      +    M D++ AGT +  LD +L       Y  HKCS  C++     +  P ++D   YK  NPLEIP HAGW R   V  G      +  I Y +PCG + R++ E+ ++L +T  KL  D+FSF+ ++ IN EF+  K  T+I DISYGKENV +PCVNS+DN+VP YIDYIP R       ++  +D+D  F++ CDCTD C++++KC+C QLT E +   +  G+     GY  +RL QF  GGI+ECNSRCSC+ +C NRVVQ GLW +LQ+FKT +KGWGIR LH IP+G F+C YAG I++E  AV EG  +GDEYQAELDYIET++++K+GYES 
Sbjct:  170 LQPSELLIGLSLTAAQPVLCRKGRDTWFPGRIISCLAPATSNDPNSTRAVGPNSAIYRVLLDSAPGAKDEICHSSLASLALAVSAADLKQKYPVGARVVSIYRDESGGIGYYSGLIAEPPSERNNHRYLLFFDDGYTQYSPPNEIYRICHQSKENWREATEGSQDFIKRYLAQYPQRPMVRLKPGQMIETELDGDWIQATVDKVDASLVLIRFSETHSEWIYRGSTRLEPLFNDL----NSTPGQAALGRSQRLEVEYGNVDASLTDKSSAFKLRKARKSATGNRDSSLTENNSAVAKTASERRGPSLRRTTSGRLEMADLECAGTIVPYLDGLLDQFVRKEYVPHKCSHSCLIALKKSSMSPVSEDPYSYKGLNPLEIPFHAGWLRYLLV--GHPNDFGRQFIVYNAPCGRQLRSMHEVQRFLDRTDSKLTTDLFSFDPNLCINSEFRAEKTFTHIADISYGKENVPVPCVNSIDNEVPGYIDYIPSRLPIG---DVPLIDDD-SFVVCCDCTDNCRDRTKCACQQLTAEASSLTNPTGMVDTQAGYRYRRLAQFTVGGIYECNSRCSCDRRCSNRVVQQGLWFRLQVFKTSRKGWGIRALHAIPKGTFLCTYAGAIYDETMAVQEGFDYGDEYQAELDYIETVEKTKEGYESA 814          

Query: 2712 VREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
             R Y  D NP+IMDAK+ GNLGRYFNHSC+PN+FVQNVFI SHD R+PEVAFF KRNI  GEE+TWDY Y V +VP KVLYCYCG P+CR RLL
Sbjct: 1408 ARTYFKDDNPYIMDAKKMGNLGRYFNHSCNPNVFVQNVFIDSHDPRFPEVAFFTKRNIAVGEEMTWDYGYTVDAVPFKVLYCYCGEPNCRIRLL 1501          

Query:  543 ISSKELLNGFQASILMPVFVKANGDVWLKGVI----EGITNKDSN----------IAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHREWIYRGSTRIEALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTD-------SKNQLIPSNNTKTSARKST-----------SKQKQEPDTNPYVN--FNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMF----NNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYAR-NHRNGI-----GYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESG 2375
            +   ELL G   ++  PV  +   D W  G I       T+ D N          I     D     +D + + +  SLA   S+ D  + YPVG RVVSIY DE+G + +YSG+IAEPP  RNN+RYL+FFDDGYTQYS  NE+Y +  Q+ ENW++  E SQ+F+K YL +YP+RPMVR+K GQ+I  E + +W    V+KVDASL  + F  TH EWIYRGSTR+E LF ++     S   ++ + +S +  VEY   D       S  +L  +  + T  R S+           + +++ P      +    M D++ AGT +  LD +L       Y  HKC+  C++     +  P ++D   YK  NPLEIP HAGW R   V  G      +  I Y +PCG + R++ E+ ++L +T  KL  D+FSF+ ++ IN EF+  K  T+I DISYGKENV +PCVNS+DN+VP YIDYIP R       ++  +D+D  F++ CDCTD C++++KC+C QLT E +   +  G+     GY  +RL QF  GGI+ECNSRC C+ +C NRVVQ GLW +LQ+FKT +KGWGIR LH IP+G F+C YAG I++E  AV EG  +GDEYQAELDYIET++++K+GYES 
Sbjct:  170 LQPSELLIGLSLTVAQPVLCRKGRDTWFPGRIISCLAPATSNDPNSTRAVGPNSAIYRVLLDSAPGAKDEVCHSSLASLALAVSAADLKQKYPVGARVVSIYRDESGGIGYYSGLIAEPPSERNNHRYLLFFDDGYTQYSPPNEIYRICHQSKENWREATEGSQDFIKRYLAQYPQRPMVRLKPGQMIETELDGDWIQATVDKVDASLVLIRFSETHSEWIYRGSTRLEPLFNDL----NSTPGQAALGRSQRLEVEYGNVDASLTDKSSACKLRKARKSATGNRDSSLTENSSTVAKAASERRGPSLRRTASGRLEMADLECAGTIVPYLDGLLDQFVRKEYVPHKCTHSCLIALKKSSMSPASEDPYSYKGLNPLEIPFHAGWLRYLLV--GHPNDFGRQFIVYNAPCGRQLRSMHEVQRFLDRTDSKLTTDLFSFDPNLCINSEFRAEKTFTHIADISYGKENVPVPCVNSIDNEVPGYIDYIPSRLPIG---DVPLMDDD-SFVVCCDCTDNCRDRTKCACQQLTAEASSLTNPTGMVDTQAGYRYRRLAQFTVGGIYECNSRCLCDRRCSNRVVQQGLWFRLQVFKTSRKGWGIRALHAIPKGTFLCTYAGAIYDETMAVQEGFDYGDEYQAELDYIETVEKTKEGYESA 814          

Query: 2646 RRHTSMHVPKVNNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            R H  +  P+             R Y  D NP+IMDAK+ GNLGRYFNHSC+PN+FVQNVFI SHD R+PEVAFF KRNI  GEE+TWDY Y V +VP KVLYCYCG P+CR RLL
Sbjct: 1384 RHHPRLQQPRKYFPVAQPDWLPARIYFKDDNPYIMDAKKMGNLGRYFNHSCNPNVFVQNVFIDSHDPRFPEVAFFTKRNIAVGEEMTWDYGYTVDAVPFKVLYCYCGEPNCRIRLL 1499          

Query:  543 ISSKELLNGFQASILMPVFVKANGDVWLKGVIEG--ITNKDSNIAEQKFDVRLENEDLLINLT---------------GFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHREWIYRGSTRIEALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTD-----------SKNQLIPSNNTKTSAR-----------------------------KSTSKQKQEPDTN-------PYVNFNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMFNNDPDA--------DDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYAR-NHRNGI-----GYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGV 2378
            +   ELL G Q +   PV  +     W  G +    + N D +  +   D   ENE+    +                  SLA   S+ +  + YPVG RVVSIY D+ G + +YSG+IAEPP  RNN RYL+FFDDGYTQYS  NEVY +  Q+ ENWK+  E SQEF+K YL +YP+RPMVR+K GQ +  E + +W    VEKVDASLA + F  TH EWIYRGSTR+E LF +++    S   +S    + +  VEY+  D           ++     + NT  S R                             K+TSK+  E + N       P  N  + +++  GT  S LDN+ K      + +HKC   C+     P +        ++   YK  NPLEIP H GW R   +A     +  K +I Y +PCG   R++ E++++L +T  +L  D+FSF+  + IN+EF+  K +TNI D+SYGKENV IPCVNSVDN+VP YIDY P R    + +    L +D +FL+ CDCTD C++++KC+C QLT E +   + NG+     GY  +RL QF  GG++ECNS C C+ +C NRVVQ GLW +LQ+FKT +KGWGIR L+ IP+G FIC YAG I++E  AV EG   GDEYQAELDYIET+++ K+GYES V
Sbjct:  170 LQPAELLLGLQLTPSQPVLYRKTQHTWFPGRVLSCHLPNSDPSTPKSDKDRAKENENAQYTIALDTSSKSKSEICFAVTSSLALAFSASELRQKYPVGARVVSIYRDDTGGIGYYSGLIAEPPSERNNQRYLLFFDDGYTQYSPPNEVYRICHQSKENWKEATESSQEFIKRYLAQYPQRPMVRLKPGQTVETELDGDWMKATVEKVDASLALMKFSRTHSEWIYRGSTRLEPLFSDLL----SSQSKSVPTHNQRVEVEYSSVDVPLDSSAKRRKARKSATGNQNTAMSVRALSSGDSHKISNSIHQTNKSLSNYNNEALKTTSKKGSEKNINEQCLSIDPITN--LSELESTGTKTSYLDNLFKEFDYKPFESHKCGHYCLKSYRKPSSALSPILCSENPVDYKGLNPLEIPFHCGWLRY--LAKYDPPVNNKCNIIYTAPCGRSLRSMHEVERFLDKTNSQLTADLFSFDSTLIINQEFRAEKTLTNIVDLSYGKENVPIPCVNSVDNEVPGYIDYTPQR----QPIGNVPLLKDSKFLVCCDCTDNCRDRTKCACQQLTVEASSLTNPNGLVDSQAGYRYRRLSQFTVGGVYECNSNCQCDRRCSNRVVQQGLWVRLQVFKTARKGWGIRALNAIPKGTFICTYAGAIYDEAMAVQEGFDCGDEYQAELDYIETVEKDKEGYESTV 847          

Query: 2712 VREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
             R Y  D NP+IMDAK+ GNLGRYFNHSC+PN+FVQNVFI +HD R+PEVAFFAKRNI+ GEE+TWDY Y V +VP KVLYCYCG P+CR RLL
Sbjct:  939 ARTYFNDINPYIMDAKKMGNLGRYFNHSCNPNVFVQNVFIDTHDPRFPEVAFFAKRNIDVGEEMTWDYGYTVDAVPFKVLYCYCGEPNCRIRLL 1032          

Query:  621 WLKGVIEGITNKDSNIAEQKFDVRLENEDLLIN--LTGFSLASIKSSLDYCKIYPVGTRVVSIYSDE-----NGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF-KEVVLRPKSKGKRST---MNKSNKTVVEYTRTDSKNQLIPSNN----TKTSARKSTSK-----QKQEPDTNPYVNFNMGDIDLAGTFISTLDNILKTRSLPA-------YTTHKCSRVCVMFNNDPDADDTNR-YKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLT------NEYARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGVXXXXXXXXXXXXXXXXXXQAKXXXXXXXXXXXXXCTEICAPKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVGNVAAKSSKT-----------------GGRRHTSMHVPKVNNDNDTVK-KFDVREYLGDPNP-FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL*F 2999
            W+K  IE I N  S  + + F V+ E +  +    L   +   I  ++    I  VGTR+++ + DE      G   +Y+GI+AE P  +N +RYLIFFDDGY QY    ++  +++ + E W  ++ DS EF+K+YL KYPERPMVR+ +GQ++  E+N +W   +V ++D SL  + F+N  R EWIYRGSTR+  LF K+   R K   +R+T   +   N   +EY   D  + L+PS+      K +ARKSTS      +KQ  D       + G+ +  GT I         R +P+       Y  H C+  CV      + DD+N+ YK  +PL +P+H G+ R         A  P+ SI+Y  PCG R R++ E+  YL QT+C++ +D F F++ +    EF+  +  + +PD++YGKE+  +  VN+ D + PPY++Y   R       +  HL+ D EFL+GCDC D C++K+KC C Q T       + +       GY  +RL      GI+ECN +C C   C NRV QNGL   LQ+FKT  KGWGIR + D+P GAFICIYAG +  +  A ++G++FGDEY AELDYIE+I+  K  YES V + E  +  E S                         I   KAT ++ +  S         + +   P  ++VE  V      + KT                 GG R  S     V+     V  +  +REY G+    +IMDAK  GN+GRY NHSC PN+FVQNVF+ +HDLR+P V+FFA ++I AG E+TWDY Y +GSVP+KVL+CYCGSPDCRGRLL F
Sbjct:  554 WVKTSIEEIVNVGSGKSPE-FVVKFERKQGVGGGGLKRVTAKQIAYNIPCPFILIVGTRIIAKFRDELKMEPIGDGQYYAGIVAEHPTPQNKFRYLIFFDDGYAQYVGIKDILLIYEYSKEVWSDVHPDSAEFIKSYLTKYPERPMVRLTLGQVVTTEWNGKWWVARVTELDCSLVKMQFENDGRCEWIYRGSTRLSPLFEKQTRQRQKKTARRTTSAPIYNKNHARIEYNYGDD-DDLVPSHGRNKPLKPTARKSTSGAHHALEKQYGDIRRLARLDYGEFE--GTIIK--------RPIPSDVPFTKEYGHHVCNSSCVY-----EYDDSNKEYKKMSPLALPLHLGFTR-------EIAKNPRRSIFYRGPCGIRIRDMEEMYDYLTQTQCQVPIDHFCFDLAVDCLNEFRHSRQHSFLPDLTYGKESAPVQVVNAFDYEYPPYVEYSSQRIAG----SGVHLNTDDEFLVGCDCEDDCRDKTKCRCWQTTYSGISFTKLSNPLYPVKGYEYRRLKDHIVSGIYECNPKCKCAKTCCNRVAQNGLKVPLQVFKTAAKGWGIRPIFDVPEGAFICIYAGQVLTDAGANEDGQQFGDEYLAELDYIESIEGVKADYESDVTDIETEEPGERSKK----------------------RIKTKKATTDKGDEESDQEVDFHAADASYHGPKPSTVERTVSTRGKHNGKTSSASGSSKNSDSDDEGEGGARPRSHFNANVDTPKAKVTNRRPLREYFGENEECYIMDAKTTGNIGRYLNHSCQPNVFVQNVFVDTHDLRFPWVSFFASKHIRAGSELTWDYNYEIGSVPNKVLFCYCGSPDCRGRLLIF 1350          

Query: 1413 GTFISTLDNILKTRSLPA------YTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSS--IYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITN----IPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXX-XXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            GT      +I ++  LP       Y  H+CS  C+   +       N+++  NPL IP+  G+ R+       + L  K S  +YY +PCG     + E+  YL +++C  L L+MF  +  + + R      + +     +PD S GKE V + CVN  D   PP ++Y   RH         +   D  F++GCDCTDGC+++++CSCHQLT +       G      GY +KRL ++ P G++ECN  C C+   C NR+VQ+G   +LQ+F T+ KGWGIR + D+ +G F+CI+ G I  E  A  +  + G+EY A LDYIE +++ K+GYES
Sbjct: 1045 GTKRPAPADIYQSTPLPVAGPWLKYVPHRCSPTCL---DQVRPAQKNQHRGQNPLLIPLLHGFRRM----TARRRLDGKMSFHVYYRAPCGQSMCEMEEVQDYLCESRCDFLFLEMFCLDPFVLVKRALLPSSMSSRPHLFLPDFSEGKELVPVSCVNETDATRPPPLNYT--RHIVCAPGVAINTSLD--FMVGCDCTDGCRDRTRCSCHQLTVDATSLFTGGPVDVNAGYTHKRLTRYVPTGVYECNPLCRCDPWMCSNRLVQHGQQLRLQLFMTQHKGWGIRCMDDLSKGTFVCIFTGKIVTETMASSDAVQAGNEYLANLDYIEEVEKLKEGYES 1372          

Query: 2742 FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            +++DAK  GN+GRY NHSCSPNLFVQNVF+ +HDLR+P VAFF  + I AG E+TWDY Y VGSV  KV+ C CGS +C GRLL
Sbjct: 1574 YLIDAKHDGNMGRYINHSCSPNLFVQNVFVDTHDLRFPWVAFFTSKRIRAGTELTWDYGYEVGSVEGKVVLCCCGSSECTGRLL 1657          

Query:  570 FQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKT----YLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKN-THREWIYRGSTRIEAL 1193
             +  I M V  +     W K  +  I   DS     ++ V+ E +     L+G  LA +   L   K   VG+RVV+ Y +++    H + +I E P  +N  R+++FFDDG++ Y    ++  V +  ++N  +  ED  E  +T    YL  YP    V +++GQ  ++E + EW    + +VD SL  + + N   +EW+Y+GS R++ +
Sbjct:  714 VEVKIDMEVLARRRTKTWHKATVLDIKETDSG---HRYKVKFEGDKGKSMLSGHHLACVNPPL--LKDLFVGSRVVATYKEKDQSWMH-AAVITEMPDRKNRMRFMVFFDDGHSTYVSLPDLRLVCK-TMKNVFEDIED--EMCRTEVVEYLKAYPNPIFVVVRVGQESKVERDGEWEDCTINQVDGSLVEICYTNDKKKEWLYKGSNRLDHI 917          

Query: 1467 YTTHKCSRVCVMFNNDPDADDT-NRYKCCNPLEIPIHAGW-----FRIKSVAGGSKAL-APKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDM--FSFEVDIRINREFQVLKVITNIP----------DISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIG----YINKRLYQFHPGGIFEXXX-XXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDE---GKKFGDEYQAELDYIETIQE--SKDGYESGVXXXXXXXXXXXXXXXXXXQAKXXXXXXXXXXXXXCTEICAP-KATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVGNVAAKSSKTGGRRHTSMHVPKVNNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            Y  H CS+ C+     P    + N Y   NPL +P+   +     F   SV    +   + ++ + Y +PCG     + ++ Q+L QT+   +L    F+F  ++  +RE    +++ + P          DIS G E V +P  N VD   P       +R+  +   +   L   P F   CDC DGC +  +C C Q      R+ + G      Y ++RL +    G+FEC        S+C NRVVQ GL  +LQ+F+T  KGWG+R   D+ +G F+CIYAG + + E ++++    K   D+  ++ D +E ++E     G ++ V E  +               +  ++ D +  +    ++    K +   +N++       +++E   K P + S E           K G   H    VPK +     V K   +E     N + +DA + GN+ R+ NHSC+PNLFVQNVF+ +H+ ++P VAFF  R+I+AG E+TW+Y Y  GS P+  + C CG  +C+  L+
Sbjct:  168 YQEHDCSQACI-----PQLPPSMNHYLGQNPLRVPLLCKFQRQCAFHCSSVEQEDELQDSVEADVLYKAPCGRGLCCMDDVLQFLQQTESLGSLQPVNFTFNPEVLPDRECPP-RLLGSAPSLSATILFERDISRGTEAVPVPLCNEVDGVRPKE-----FRYRKERWPHGCFLSAAPFFSACCDCADGCTDVKRCLCLQ------RSLKAGAAPKQLYDHQRLNEPVSTGLFECGPWCACEKSKCLNRVVQRGLRVRLQVFRTSDKGWGVRCRDDLDKGTFVCIYAGVVLSLEQSLEDPISSKNVKDDAASD-DEVEVVEEWTLPTGQKTTVTETLDISPPLYVPVIKRPADQTSVVLDGEKEQLEQQDLQEEIKTSSPDSNKTEMKDQDDKKEEVVRKKPRLESKE-----------KKGDTPHPDQAVPKGH-----VLKQGPQE-----NMYYLDASKEGNVARFINHSCNPNLFVQNVFVDTHNPKFPLVAFFTCRSIKAGTELTWNYSYNPGSDPEHEVPCLCGYKNCQTILI 667          

Query: 1467 YTTHKCSRVCVMFNNDPDADDT-NRYKCCNPLEIPIHAGW-----FRIKSVAGGSKAL-APKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDM--FSFEVDIRINREFQVLKVITNIP----------DISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIG----YINKRLYQFHPGGIFEXXX-XXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDE---GKKFGDEYQAELDYIETIQE--SKDGYESGVXXXXXXXXXXXXXXXXXXQAKXXXXXXXXXXXXXCTEICAP-KATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVGNVAAKSSKTGGRRHTSMHVPKVNNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            Y  H CS+ C+     P    + N Y   NPL +P+   +     F   SV    +   + ++ + Y +PCG     + ++ Q+L QT+   +L    F+F  ++  +RE    +++ + P          DIS G E V +P  N VD   P       +R+  +   +   L   P F   CDC DGC +  +C C Q      R+ + G      Y ++RL +    G+FEC        S+C NRVVQ GL  +LQ+F+T  KGWG+R   D+ +G F+CIYAG + + E ++++    K   D+  ++ D +E ++E     G ++ V E  +               +  ++ D +  +    ++    K +   +N++       +++E   K P + S E           K G   H    VPK +     V K   +E     N + +DA + GN+ R+ NHSC+PNLFVQNVF+ +H+ ++P VAFF  R+I+AG E+TW+Y Y  GS P+  + C CG  +C+  L+
Sbjct:  160 YQEHDCSQACI-----PQLPPSMNHYLGQNPLRVPLLCKFQRQCAFHCSSVEQEDELQDSVEADVLYKAPCGRGLCCMDDVLQFLQQTESLGSLQPVNFTFNPEVLPDRECPP-RLLGSAPSLSATILFERDISRGTEAVPVPLCNEVDGVRPKE-----FRYRKERWPHGCFLSAAPFFSACCDCADGCTDVKRCLCLQ------RSLKAGAAPKQLYDHQRLNEPVSTGLFECGPWCACEKSKCLNRVVQRGLRVRLQVFRTSDKGWGVRCRDDLDKGTFVCIYAGVVLSLEQSLEDPISSKNVKDDAASD-DEVEVVEEWTLPTGQKTTVTETLDISPPLYVPVIKRPADQTSVVLDGEKEQLEQQDLQEEIKTSSPDSNKTEMKDQDDKKEEVVRKKPRLESKE-----------KKGDTPHPDQAVPKGH-----VLKQGPQE-----NMYYLDASKEGNVARFINHSCNPNLFVQNVFVDTHNPKFPLVAFFTCRSIKAGTELTWNYSYNPGSDPEHEVPCLCGYKNCQTILI 659          

Query: 2727 GDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct: 1032 GEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGSTECRGRLL 1120          

Query:  588 MPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYC----KIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF 1196
            M +  K     W +G +  I +  ++    K+ V+ EN+   + L+G  +A      DY     ++Y VG RVV+ Y D N  V  Y+GI+AE P ++N  R+LIFFDDGY  Y    ++Y + +   ++W+ + ++S ++F++ Y+  YP RPMV +K GQ+I+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F
Sbjct:  224 MSILGKKRTKTWHRGTLVAINSVGNSF---KYKVKFENKGKSL-LSGNHVA-----FDYHPTLERLY-VGARVVAKYKDGNQ-VWLYAGIVAEMPNSKNRMRFLIFFDDGYASYVGLPDLYPICRPLQKSWEDIEDESCRDFIQEYITAYPNRPMVLLKPGQIIKTEWEGTWWRSRVEEVDGSLVKMLFLDDKRSEWIYRGSTRLEPMF 421          

Query: 1914 LNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            L+++++ E   +L    C       SKC+CHQLT +       G      GY +KRL +  P GI+ECN RC CN Q   NR+VQ+GL  +LQ+FKT+ KGWGIR L D+ +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES
Sbjct:  633 LSLRNMGEIQRYLFQTTCDFIYLEMSKCACHQLTLQATGCTPGGQINANAGYNSKRLDECLPTGIYECNKRCRCNHQMCINRLVQHGLQVRLQLFKTQNKGWGIRCLDDVAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYES 791          

Query: 1761 NREFQVLKVITNIPDISYGKENVKIPCVNSVDND-VPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNE--YARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELD 2330
            NR  +  ++I +  D++ G ENV IPCVN VD++  P    YI      + + +  ++D +   L  C CTD C + S C C QL+    Y ++ R     + +   +  P  IFECN  CSC   C+NRVVQ G+  +LQ+++TEK GWG+R L DIP+G+FIC Y G + ++  A     +  D Y  +LD
Sbjct:   34 NRIIRTERIICS--DVAQGYENVPIPCVNGVDDEGCPSDYKYIAE----NCETSAMNIDRNITHLQHCSCTDDCSS-SNCLCGQLSIRCWYDKDQR-----LLQEFNKIEPPLIFECNLACSCYKSCKNRVVQAGMKVRLQLYRTEKMGWGVRALQDIPQGSFICEYVGELISDAEA---DVREDDSYLFDLD 211          

Query: 2709 DVRE---YLGDPN-----PFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCR 2981
            DVRE   YL D +      + +DA+  GN+ R+ NH C PN+    VF+   DLR+P +AFF+ R+I  G+E+ +DY  R   +  K   C CGS  C+
Sbjct:  199 DVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDILTGQELGFDYGDRFWDIKSKYFTCQCGSEKCK 297          

Query:  588 MPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNE-DSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALFK----EVVLRPKSKGKRSTMNKSNK--TVVEYTRTDSKNQLIPSN-------------------------NTKTSARKSTSKQKQEPDTN--------PYVNFN-------MGDIDLAGTFISTLDNILKT-----------RSLPAY------------TTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDY----IPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNG-----IGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGY 2366
            M V  K     W +G++  I +  S     K+ V+ +++   + L+G  +A  +       +  VG+RVV+ Y D +  V  Y+GI+AE P   N YR+LIFFDDGY  Y    E+Y V +Q   +W+ +++  S+EF++ Y+  YP RPMV +K GQ I+ E+   W  +++E+VD SL  + F    R EWIYRGSTR+E +          +P  + + +T    NK   VV+Y + + +    P                           N K  A+KST+ ++    T         P  N++       +  + L  T  +   N LK            +SL  Y              H CS+ C+      + D   +YK  NPL +P+   + R+ +    ++  AP   + Y +PCG   R ++E+ +YL +T    L L+ F F+  +   R    +K +  + DI+ G E+V + CVN +D++ PP   Y    IP    F        ++  PEFL+ C CTDGC++KSKC+C QLT +       G      GY NKRL +  P GI+ECN +C CN +  +NR+VQ+GL  +LQ+FKT+ KGWGIR L DI +G+++CIYAG I  ++TA  EG + GDEY A LDYIE+++  KDGY
Sbjct:  178 MRVLGKKRTKTWHRGILVAIVSSASGF---KYKVKFDSKGKSL-LSGNHIAYDRHPESESLV--VGSRVVAKYKDGSS-VWLYAGIVAETPHRTNKYRFLIFFDDGYASYVTLLELYEVCRQLTNSWEDVDDRASREFMEDYIKSYPNRPMVLLKPGQNIKTEWEGTWWKSRIEEVDGSLVKIVFLIDERCEWIYRGSTRLEPMHTLKHYHTEKKPGQRMRPTTAAGRNKGGPVVQYPQQEPQQHTKPQTPPFSPVPPKSQQLCSSHSESSLNSANRKQVAKKSTTFRQVTTSTRITDSDITWPATNYSYMPRINKLIQMTLGTTCATFTTNYLKCPVAHLILGRLLQSLATYPIYKAPKEKLLYVPHACSQSCLRSLRPANLD---KYKGRNPLLVPLLYDFRRLSARRKINRK-AP-FHMMYRAPCGRSLRCMMEVQRYLFETYANFLFLEQFCFDPYVMAERRISTVKPLYCVRDITNGVEDVPVSCVNEIDSEPPPDAAYSKVRIPEHGVF--------INTSPEFLVCCSCTDGCQDKSKCACQQLTVDATGCSPGGQTNTDAGYHNKRLEECLPTGIYECNKQCKCNVRMCQNRLVQHGLQVRLQLFKTQNKGWGIRCLDDISKGSYVCIYAGKILTDDTADKEGLEMGDEYFANLDYIESVERHKDGY 832          

Query: 2532 STVITKPQEQEPAMKNPLVASVEGNVGNVAAKSSKTGGRRHTSMHVPKVNNDNDTVKKFDVREYL-GDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            S +  +P +++ A+K     + +     VA KS  TG RR             +  +K   RE+  G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSVP K L CYCGS +CRGRLL
Sbjct: 1069 SDLADRPLKRQVAVKRGF--AFKTTARGVAVKS--TGMRR--------TGEGGNQPEKKSTREFFDGEDSCYIIDAKLIGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYSYEVGSVPGKELLCYCGSTECRGRLL 1211          

Query: 2712 VREYLGDPNPFI------MDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYR-----VGSVPD------KVLYCYCGSPDCRGRL 2990
            VRE+ GD           +D +R GN+GR+ NHSC PNL +    ++ H +  P +A FA R+I  GEE+ +DY  R     V + PD      +   C+CG+P CRG L
Sbjct:  184 VREHAGDGRGVAPATSTYVDPERVGNVGRFLNHSCEPNLVM--ALVRVHSV-LPRLALFAARDIADGEELCYDYSGREDSSAVCASPDGDGVAGQRKPCFCGAPSCRGVL 290          

Query: 1803 DISYGKENVKIPCVNSVDNDVPPYIDYIP-YRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGG----IFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFN 2270
            D++ G E++ I   N +  +   Y  Y P Y       ++   L      L GC+C DG  + S  +C  L     R   +G    +         G    IFECN  C C   C +RVVQ GL  +LQ+F+T +KGW +RTL  + RG F+C Y G +  
Sbjct:    8 DVAQGLESLPIELTNGLPTESLKYGQYTPDYVRGPGCAVDPGELT-----LPGCECADGRCDASPVACPCL-----RGGGDGAACYDPAGRLVGDAGFARPIFECNPLCRCGDACPSRVVQKGLAVRLQVFRTARKGWAVRTLEPLGRGRFVCEYVGEVLG 158          

Query: 2742 FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSV------PDKVLY--------------CYCGSPDCRGRL 2990
            + +DA   GN+  + NHSC PNL V + FI +HD   P +AFFA  ++ AGEE+T+DY  +  S        D VL+              C CG+  CR  L
Sbjct:  318 YTVDATFYGNISHFVNHSCEPNLQVYSTFINNHDFSQPRIAFFAMDDLAAGEELTFDYNIKDSSSQNESCNKDTVLHTTVTTSPKQRARITCKCGASTCRKFL 420          

Query: 2745 IMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRL 2990
            I+DA + GNL R+ NHSC+PN + + + ++S       +  ++K+ I   EEIT+DY +    + +  + C CG+  CRG L
Sbjct: 1779 IIDATKVGNLARFINHSCNPNCYAKVITVESQK----RIVIYSKQAINVNEEITYDYKF---PIEENKIPCLCGAEHCRGTL 1853          

Query: 2745 IMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCR 2981
            ++DA   G   RY NHSCSPN   + V   + D    ++   + R ++ GEE+T+DY +       K+  C+CG+P+CR
Sbjct:   58 VIDATLTGGPARYINHSCSPNCVAEVV---NFDKERSKIIIISSRRLQKGEELTYDYKFDFEDDQHKIP-CHCGAPNCR 132          

Query: 2745 IMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDY-MYRVGSVPDKVLYCYCGSPDCRGRL 2990
             +DA   G+L R+ NHSCSPN +V N ++    LR   +  FA+R I  GEEIT+DY + R G+   K   CYC  P+C G L
Sbjct:  184 FIDATIKGSLARFCNHSCSPNAYV-NKWVVKDKLR---MGIFAQRKILKGEEITFDYNVDRYGAQAQK---CYCEEPNCIGFL 259          

Query: 2745 IMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRL 2990
            ++DA + G + R+ NH C PN   +   IK    R   +  +A R+I A EE+T+DY +      ++ L C CG+P+C+G L
Sbjct: 1002 VIDATKKGGIARFINHCCDPNCTAK--IIKVGGRR--RIVIYALRDIAASEELTYDYKFEREKDDEERLPCLCGAPNCKGFL 1079          

Query: 2691 DTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            D +++   R   G+ + +++DAK  GN GRY NHSCSPNLFVQNVFI +HDLR+P VAFFA+ NI AG E+TWDYMY VGSV DK L CYCGS +CRGRLL
Sbjct:   80 DHIERPTTRSLFGEEHCYVIDAKAYGNCGRYLNHSCSPNLFVQNVFIDTHDLRFPWVAFFAQHNIPAGSELTWDYMYEVGSVQDKELRCYCGSSECRGRLL 180          

Query: 2142 VVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIE 2339
            VVQNG+  +LQ+FKT+ +GWG+RTL D+P G FIC Y+G I NEE A  EG+ +GDEY AELD+IE
Sbjct:   18 VVQNGIQLRLQVFKTKSRGWGLRTLDDVPCGTFICTYSGQIMNEEMANKEGRDYGDEYLAELDHIE 83          

Query: 2553 QEQEPAMKNPLVASVEGNVGNVAAKSSKTGGRRHTSMHVPKVNNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYM 2918
            +  +P MKN  V    G V  +  + ++  GR + +               FD+    GD   + +DAK+ GN+  + NHSC PNL V  V++ + D + P +AFFA+R+I AGEEIT+DY+
Sbjct:  134 KTMDPIMKNQFVTEYVGEV--ITNEEAEHRGRHYDAA---------GQTYLFDLDYNDGD-CAYTIDAKKYGNISHFINHSCDPNLSVFGVWVDTLDPQMPRIAFFARRDIPAGEEITFDYL 243          

Query: 1845 NSVDNDVPPYIDYIPYRHHFDEDLNMQHLDE--DPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGG-IFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKK-GWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKF---GDEYQAELDY 2333
            N VDN  PP  D++    +  ++     LD   D  +L+GC+C   C  KS C C        +N      Y      QF PG  I+ECNS+CSC+  CRNRVVQ G   ++ IF+T    GWG++T+  I +  F+  Y G +   E A   G+ +   G  Y  +LDY
Sbjct:   23 NKVDN-TPPPTDFV----YISQNKVPSFLDHLFDHNYLVGCNCQR-CTPKS-CEC-------PKNSGGVFAYDRFGRVQFEPGKPIYECNSKCSCSESCRNRVVQRGRTVRVTIFRTYNGCGWGVKTMDPIMKNQFVTEYVGEVITNEEAEHRGRHYDAAGQTYLFDLDY 178          

Query: 2745 IMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRL 2990
            I+DA   GN  R+ NH C PN + + + +++      ++  ++KR+I+  EEIT+DY +    + D+ + C CG+P CRG L
Sbjct:  138 IIDATTMGNFARFINHCCDPNCYAKVIAVENM----KKIVIYSKRDIQVDEEITYDYKF---PIEDEKIPCLCGAPQCRGTL 212          

Query: 2745 IMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDY-MYRVGSVPDKVLYCYCGSPDCRG 2984
            I+DA   G++ R+ NHSC PN   Q   +         + FF  R I+AGEE+T+DY + R G +      CYC SP CRG
Sbjct:  141 IIDATLKGSISRFINHSCEPNCVTQKWTVNG----LLRIGFFTLRTIKAGEELTFDYQLQRYGKIAQT---CYCESPSCRG 214          

Query: 2742 FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRL 2990
            +++DA  +GN  R+ NHSC PN + + V I  +     ++  FA ++I  GEE+T+DY +    + D+ L C+C S  CR  L
Sbjct:  212 YVVDATTSGNAARFINHSCEPNCYSRVVTIDGNK----KILIFASKSISRGEELTYDYKF---PLEDEKLPCHCKSKRCRKYL 287          

Query: 1467 YTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSS--IYYVSPCGHRTRNIIELDQYLVQTKCK-LNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEY------ARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXX-XXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYES 2372
            Y  H C   C +    P   D +R K  NPL  P+   + R+     G + +  K S  + Y +PCG   RN+ E+  YL QT+C  + L+MF  +  + ++R FQ  +    IPDI+ GKE++ + CVN +DN  PP + Y   +    ED    +  +D  FL+GCDCTDGC++KSKCSCHQLT +       A+ + N  GY++KRL +  P GI+ECN RC C +Q   NR+VQ+GL  +LQ+FKT+ KGWGIR L D+ +G+F+CIYAG I  ++ A  EG + GDEY A LD+IE+++  K+GYES
Sbjct:  600 YLAHTCQPAC-LNRVRPVKPDIHRGK--NPLLTPLLYDFRRMT----GRRKVNRKMSFHVIYKAPCGLCLRNMPEIQNYLFQTRCDFIFLEMFCLDPYVLVDRPFQPQRPFYYIPDITGGKEDIPLSCVNEIDNTPPPKVKY--SKERIPEDGVFINTSDD--FLVGCDCTDGCRDKSKCSCHQLTLQATACTPGAQINPNA-GYLHKRLEECLPTGIYECNKRCKCCAQMCTNRLVQHGLQVRLQLFKTQNKGWGIRCLDDVAKGSFVCIYAGKILTDDFADKEGLEMGDEYFANLDHIESVENFKEGYES 899          

Query: 2727 GDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            G+ + +I+DAK  GNLGRY NHSCSPNLFVQNVF+ +HDLR+P VAFFA + I AG E+TWDY Y VGSV  K L C CGS +CRGRLL
Sbjct: 1150 GEESCYIIDAKLEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVEGKELLCCCGSTECRGRLL 1238          

Query:  582 ILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLI--NLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDS-QEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHR-EWIYRGSTRIEALF 1196
            I M +  K     W +G +  I      +   K+ V+ +    L+  N   F       SL       VG RVV+ Y D N  V  Y+GI+AE P N+N  R+LIFFDDGY  Y    E+Y V +     W+ + + S ++F++ Y+  YP RPMV +K GQ+I+ E+   W  ++VE+VD SL  + F +  R EWIYRGSTR+E +F
Sbjct:  219 IGMNILGKKRTKTWHRGTLVAINPIGGGV--YKYKVKFDKGKSLLSGNHVAFDYNPTLESLF------VGARVVAKYKDGN-LVWLYAGIVAEMPNNKNRMRFLIFFDDGYASYVILPELYPVCRPLKHTWEDIEDASCRDFIEEYISAYPSRPMVLLKAGQIIKTEWEGTWWKSRVEEVDGSLVKILFLDDKRSEWIYRGSTRLEPMF 418          

Query: 1467 YTTHKCSRVCV-MFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAG--GSKA--------LAPKSSIYYVSPCGHRTRNIIELDQYLVQTKC--KLNLDMFSF----EVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPE-FLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFEXXX-XXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDE 2291
            Y  H+C + C+      P    T  +   NPL++P+  G+ R+ S  G  GS +              + Y +PCG   R+  ++  +LV T+    L +D F+F    E+D     + Q+L     I D+S G E   +          PP      +R+  D   +   L + P  F   CDCTDGC +   C+C  +T         G GY  +RL Q    G+FEC        ++C+NR+VQ G+  +LQ+F+TE +GWG+R   D+ RG F+CIYAG +  +  + DE
Sbjct:  130 YQPHQCCKACLPSLPRMPQP--TLPFWGQNPLKVPLLCGFKRLMSQPGRGGSPSGEEEEEEEEEAACDVVYKAPCGQSLRSFEDVMLFLVATESYDLLQVDFFTFNPSVELDPPSVSDAQIL-----IKDLSRGLEPTPVELCAPNVGSRPPE-----FRYRKDRWPHGCFLSQGPTLFSACCDCTDGCSDARSCACVAMTT-------RGRGYSYRRLLQPVESGLFECGPWCDCDRARCQNRLVQRGIRARLQVFQTEDRGWGVRCRDDLDRGTFVCIYAGVVLQKVLSPDE 404          

Query: 2748 MDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKV--LYCYCGSPDCRGRLL*FSDV 3008
            +DA + GN+ R+ NHSC PNLF+QNVFI SHD  +P VAFF +R ++AG E+TW+Y      +P +   + C C S  C+  LL   DV
Sbjct:  523 VDASKEGNVSRFINHSCQPNLFIQNVFIDSHDPVFPVVAFFTRRAVKAGTELTWNYAAYTPGLPQQKQEVPCLCRSDKCQQWLLIDDDV 611          

Query: 1803 DISYGKENVKIPCVNSVDNDVPP----YIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETA 2282
            D+S G+E V IPCVNSVDN+  P    YI         + D N+ HL         C C + C + S C C QL+    R   +  G +     +  P  IFECN  CSC   CRNRVVQ GL  +LQ+F+T KKGWG+R L DIP+G F+C Y G I +E  A
Sbjct:  961 DVSLGQERVPIPCVNSVDNEPHPEDYKYISENCVTSPLNIDRNITHLQY-------CVCKEDCSS-SICMCGQLS---LRCWYDKHGRLLPEFCREEPPLIFECNHACSCWKTCRNRVVQKGLRTRLQLFRTRKKGWGVRALQDIPKGTFVCEYVGEIISEAEA 1113          

Query: 2697 VKKFDVREYLGDPNP---FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCR 2981
            +++ D   +  D  P   + +DA+  GN+ R+ NH C PNLF   VF    DLR+P VAFFA  NI+AGEE+ ++Y      V  K+  C CGSP C+
Sbjct: 1115 MRQMDAYLFSLDDKPQDLYCIDARFYGNISRFLNHMCEPNLFACRVFTTHQDLRFPHVAFFASENIKAGEELGFNYGDHFWEVKSKLFTCECGSPKCK 1212          

Query: 1803 DISYGKENVKIPCVNSVDNDVPP----YIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETA 2282
            D+S G+E V IPCVNSVDN+  P    YI         + D N+ HL         C C + C + S C C QL+    R   +  G +     +  P  IFECN  CSC   CRNRVVQ GL  +LQ+F+T KKGWG+R L DIP+G F+C Y G I +E  A
Sbjct: 1046 DVSLGQERVPIPCVNSVDNEPHPEDYKYISENCVTSPLNIDRNITHLQY-------CVCKEDCSS-SICMCGQLS---LRCWYDKHGRLLPEFCREEPPLIFECNHACSCWKTCRNRVVQKGLRTRLQLFRTRKKGWGVRALQDIPKGTFVCEYVGEIISEAEA 1198          

Query: 2697 VKKFDVREYLGDPNP---FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCR 2981
            +++ D   +  D  P   + +DA+  GN+ R+ NH C PNLF   VF    DLR+P VAFFA  NI+AGEE+ ++Y      V  K+  C CGSP C+
Sbjct: 1200 MRQMDAYLFSLDDKPQDLYCIDARFYGNISRFLNHMCEPNLFACRVFTTHQDLRFPHVAFFASENIKAGEELGFNYGDHFWEVKSKLFTCECGSPKCK 1297          

Query: 1803 DISYGKENVKIPCVNSVDNDVPP----YIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETA 2282
            D+S G+E V IPCVNSVDN+  P    YI         + D N+ HL         C C + C + S C C QL+    R   +  G +     +  P  IFECN  CSC   CRNRVVQ GL  +LQ+F+T KKGWG+R L DIP+G F+C Y G I +E  A
Sbjct:  994 DVSLGQERVPIPCVNSVDNEPHPEDYKYISENCVTSPLNIDRNITHLQY-------CVCKEDCSS-SICMCGQLS---LRCWYDKHGRLLPEFCREEPPLIFECNHACSCWKTCRNRVVQKGLRTRLQLFRTRKKGWGVRALQDIPKGTFVCEYVGEIISEAEA 1146          

Query: 2697 VKKFDVREYLGDPNP---FIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCR 2981
            +++ D   +  D  P   + +DA+  GN+ R+ NH C PNLF   VF    DLR+P VAFFA  NI+AGEE+ ++Y      V  K+  C CGSP C+
Sbjct: 1148 MRQMDAYLFSLDDKPQDLYCIDARFYGNISRFLNHMCEPNLFACRVFTTHQDLRFPHVAFFASENIKAGEELGFNYGDHFWEVKSKLFTCECGSPKCK 1245          

Query:   18 MSSDPEKIDFKSLFDNDNFENWARQSFADDDFHKNLLNYIFGNYGDVLNELQENQTLIKIDEICDEIIRKYEIDEMLLREFNKAGFSQLHLSLNNLEMCNKKLDVLEDLFARTNSLASNLGVPNSSEEAXXXXXXXXXXXXXXXXXXXQIVSLTSKRKSRNTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHREWIYRGSTRIEALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTDSKNQLIPSNNTKTSARKSTSKQKQEPDTNPYVNFNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGVXXXXXXXXXXXXXXXXXXQAKXXXXXXXXXXXXXCTEICAPKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVGNVAAKSSKTGGRRHTSMHVPKVNNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            MSSDPEKIDFKSLFDNDNFENWARQSFADDDFHKNLLNYIFGNYGDVLNELQENQTLIKIDEICDEIIRKYEIDEMLLREFNKAGFSQLHLSLNNLEMCNKKLDVLEDLFARTNSLASNLGVPNSSEEAIVIDDDDDDEITINNDDDVQIVSLTSKRKSRNTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHREWIYRGSTRIEALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTDSKNQLIPSNNTKTSARKSTSKQKQEPDTNPYVNFNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFECNSRCSCNSQCRNRVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGVEEPEESDSKENSDDDSNDQAKAELLADSDDSESSCTEICAPKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVGNVAAKSSKTGGRRHTSMHVPKVNNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL
Sbjct:    1 MSSDPEKIDFKSLFDNDNFENWARQSFADDDFHKNLLNYIFGNYGDVLNELQENQTLIKIDEICDEIIRKYEIDEMLLREFNKAGFSQLHLSLNNLEMCNKKLDVLEDLFARTNSLASNLGVPNSSEEAIVIDDDDDDEITINNDDDVQIVSLTSKRKSRNTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHREWIYRGSTRIEALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTDSKNQLIPSNNTKTSARKSTSKQKQEPDTNPYVNFNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFECNSRCSCNSQCRNRVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGVEEPEESDSKENSDDDSNDQAKAELLADSDDSESSCTEICAPKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVGNVAAKSSKTGGRRHTSMHVPKVNNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 992          

Query:   18 MSSDPEKIDFKSLFDNDNFENWARQSFADDDFHKNLLNYIFGNYGDVLNELQENQTLIKIDEICDEIIRKYEIDEMLLREFNKAGFSQLHLSLNNLEMCNKKLDVLEDLFARTNSLASNLGVPNSSEEAXXXXXXXXXXXXXXXXXXXQIVSLTSKRKSRNTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHREWIYRGSTRIEALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTDSKNQLIPSNNTKTSARKSTSKQKQEPDTNPYVNFNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGVXXXXXXXXXXXXXXXXXXQAKXXXXXXXXXXXXXCTEICAPKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVGNVAAKSSKTGGRRHTSMHVPKVNNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 2993
            MSSDPEKIDFKSLFDNDNFENWARQSFADDDFHKNLLNYIFGNYGDVLNELQENQTLIKIDEICDEIIRKYEIDEMLLREFNKAGFSQLHLSLNNLEMCNKKLDVLEDLFARTNSLASNLGVPNSSEEAIVIDDDDDDEITINNDDDVQIVSLTSKRKSRNTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHREWIYRGSTRIEALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTD     IPSNNTKTSARKSTSKQKQEPDTNPYVNFNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFECNSRCSCNSQCRNRVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGVEEPEESDSKENSDDDSNDQAKAELLADSDDSESSCTEICAPKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVGNVAAKSSKTGGRRHTSMHVPKVNNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL
Sbjct:    1 MSSDPEKIDFKSLFDNDNFENWARQSFADDDFHKNLLNYIFGNYGDVLNELQENQTLIKIDEICDEIIRKYEIDEMLLREFNKAGFSQLHLSLNNLEMCNKKLDVLEDLFARTNSLASNLGVPNSSEEAIVIDDDDDDEITINNDDDVQIVSLTSKRKSRNTEKSSLNLSNCLQYISSKELLNGFQASILMPVFVKANGDVWLKGVIEGITNKDSNIAEQKFDVRLENEDLLINLTGFSLASIKSSLDYCKIYPVGTRVVSIYSDENGCVAHYSGIIAEPPGNRNNYRYLIFFDDGYTQYSCQNEVYCVFQQNLENWKQMNEDSQEFVKTYLDKYPERPMVRMKIGQLIRIEYNSEWCPTKVEKVDASLAYVNFKNTHREWIYRGSTRIEALFKEVVLRPKSKGKRSTMNKSNKTVVEYTRTD-----IPSNNTKTSARKSTSKQKQEPDTNPYVNFNMGDIDLAGTFISTLDNILKTRSLPAYTTHKCSRVCVMFNNDPDADDTNRYKCCNPLEIPIHAGWFRIKSVAGGSKALAPKSSIYYVSPCGHRTRNIIELDQYLVQTKCKLNLDMFSFEVDIRINREFQVLKVITNIPDISYGKENVKIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGCKNKSKCSCHQLTNEYARNHRNGIGYINKRLYQFHPGGIFECNSRCSCNSQCRNRVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDEYQAELDYIETIQESKDGYESGVEEPEESDSKENSDDDSNDQAKAELLADSDDSESSCTEICAPKATGNQTNRSSTVITKPQEQEPAMKNPLVASVEGNVGNVAAKSSKTGGRRHTSMHVPKVNNDNDTVKKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRLL 987          

Query: 2706 FDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPD 2942
            FD+ ++ GDP  F +DA + GN+  + NHSC+PN+  + VFI + D+R P +AFFA R+I+AGEE+T+DYM   G++ D
Sbjct:  357 FDL-DFAGDPE-FTVDAYKKGNMSHFINHSCNPNMTSRCVFINNLDIRMPRIAFFAARDIKAGEELTFDYM-MTGAISD 432          

Query: 1830 KIPCVNSVDNDVPPYIDYIPYRHHFDEDLNMQHLDEDPEFLMGCDCTDGC-KNKSKCS-CHQLTNEYARNHRNGIGYINKRLYQFHPGGIFEXXXXXXXXXXXXXXVVQNGLWNKLQIFKTEKKGWGIRTLHDIPRGAFICIYAGTIFNEETAVDEGKKFGDE---YQAELDYIETIQESKDGYESG 2375
            K+   N+VD + PP +D+      F  D     ++   +  + C CT  C  NK  CS  H     Y          +  ++       I+ECNS CSC+  C  RVVQ G+  +L+IF+T+ +GWG++TL  I RG FI  Y G I   + A + GK +  +   Y  +LD+    + + D Y+ G
Sbjct:  204 KVTVENTVDTEGPP-LDF-----QFITDYVSSSIEIHSDPPIACHCTTSCIDNKKDCSSIHGGDPPYT---------VTGKVIPKFGVPIYECNSACSCDLNCPYRVVQRGVKLQLKIFRTKNRGWGLKTLTKIIRGNFIMEYLGEIVAVDEAEERGKLYDQQNLTYLFDLDFAGDPEFTVDAYKKG 375          

Query: 2700 KKFDVREYLGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCR 2981
            KK  +  +  DP+  ++DA RAG+L RY NH C PN F + +  +    +   +   + R IE GEE+T+DY + +    D  + C CG+ +CR
Sbjct: 1372 KKQGIYMFRLDPST-VIDATRAGDLARYINHCCDPNCFTELLDFE----KESHIVIISNRKIEKGEELTYDYKFDLDDGKDDKIPCLCGARNCR 1460          

Query: 2697 VKKFDVREY-----LGDPNPFIMDAKRAGNLGRYFNHSCSPNLFVQNVFIKSHDLRYPEVAFFAKRNIEAGEEITWDYMYRVGSVPDKVLYCYCGSPDCRGRL 2990
             KKF+ +++      GD    ++DA   GNL RY NHSC PN +++N  +      YP+   FA + I + +E+T+DY    G +  +  +C C S +C G L
Sbjct:  611 AKKFNAKDFYMIHLTGD---LVIDAGPKGNLSRYMNHSCDPNCYLENWIVNG----YPKKGVFALKEIGSDQELTFDYRIS-GVIMKEDAFCLCSSNNCTGFL 705