Exonuclease 3'-5' domain-containing protein 1

Overview
NameExonuclease 3'-5' domain-containing protein 1
Smed IDSMED30026777
Length (bp)2692
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Exonuclease 3'-5' domain-containing protein 1 (SMED30026777) t-SNE clustered cells

Violin plots show distribution of expression levels for Exonuclease 3'-5' domain-containing protein 1 (SMED30026777) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Exonuclease 3'-5' domain-containing protein 1 (SMED30026777) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Exonuclease 3'-5' domain-containing protein 1 (SMED30026777) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30026777

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30026777h1SMcG0022707 SmedASXL_017103SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30026777h1SMcG0022707 dd_Smed_v4_14291_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30026777h1SMcG0022707 dd_Smed_v4_14291_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30026777h1SMcG0022707 dd_Smed_v4_14291_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30026777h1SMcG0022707 dd_Smed_v4_14291_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30026777h1SMcG0022707 dd_Smed_v6_14291_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30026777h1SMcG0022707 dd_Smed_v4_14291_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. TrEMBL
Match: A0A433U4P3 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_003437 PE=4 SV=1)

HSP 1 Score: 249.21 bits (635), Expect = 2.187e-66
Identity = 202/781 (25.86%), Postives = 368/781 (47.12%), Query Frame = 2 
Query:  248 LCVENIIHCLELFENVVEFLGIFKEIMKEIKDDLTEAIFSRTLTVT-----EKDSLERIERIPYFELCRQSLEIQEVKSLEFQKINDTFTKECCRL-----------------ENELKLLND-------INKEKENQCLEYKREIFXXXXXXXXXXXXXXSMQEEKLEMTKSTQNIFEKIDEENIILKNEINRQKAIIDDLKHFKESHEHLNKSF-EQACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDFDKRIMGFKEKMMSCINDGDN------------EDNDQFIVTSILEMQNNKLHFKNEFSLVQIESLMLQNHQAVLINDWSVIEESEA----KKELTFVKD------------------IKSSFTIDNRILNKYSVLIYISND-GESFYECKEVRFCESCGNRSVFCPHTYQ-KEKVIKLPVGSTHMKIQHPEIRINSKYA----KFFVTKPFFEIEEKLQINSNEERXXXXXXXXXXXXXXTDTET----------IISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLF--KELAIFYTDDGFQEIAPFSRITEIVAFLSF 2344
            L  + I+   +  + ++  LG+F  I +++++DL EA++S  LT T       DS E I+R+PYF L +Q   +   ++   +K+++       RL                 E+ + +LN        I ++K+ Q  E +R++          +   ++ Q+++  M     ++ E ++E     KNEIN        L  FK+ ++ +  +F ++A    E     +   +  K+ANL + +++   +  ++  + N  ++++DK +   K  ++  +   D             E+ DQ       E++  ++ F+N    +  E  +LQ H  +L+    ++EE +     KKE+    D                  +   F    R+ +KY+ ++Y +N+ G++F E K+ ++C SCG ++V CPH     EK+  LP   TH+KI  P++RIN        K     P  +    +                 +  ++T  E+          + + + L +D+  RT+++RT  R     +  S++E F A +   DE+   +    +ILD LY F  DRY  E    ++ +DF +++ E +   + IQL  HV VGN+D+S +RY+  + + ++AVDWK  ED R F S+V+PFLNEDD++S+ +SY S+SEN   +  +  F I+  LK R+PRF  + ++ V  ++   G  T  EF+  L+SL  L N+++  RLF   E A+ +  DG     P  R+ +I  +L+ 
Sbjct:   33 LTEDRILLAFQALDELIPNLGVFTRIFQKLREDLFEAVYSDELTGTCASPGIGDS-EFIQRLPYFSLVKQ---VYHERNEHMEKLDEQLDTVKERLFDKHKQLEKAQETIADKEDHISVLNSTKDDLQSIIEDKDKQIEELERDL----------EETRENAQDKQHHMECDISDLRESLEE----AKNEINY-------LSQFKKGYDDMYYAFMDKAGTPDEKPKRDKKSVIATKRANLLSGVESAQKLEEQILTVMNTAIEEYDKYVETHKADLLEKVTSEDMTEAEMDLQELEIEEADQ-------ELEAIQIRFQNTVGNIMTELGLLQQHSTMLMEQLQILEEIKPAVPKKKEVNRGLDKGDSILSVGLEEEEISEEVADPFIPQERVFSKYAAMLYTTNNQGKTFEEFKDAKYCASCGEKTVICPHKLGGSEKIFILPHNCTHIKITRPKVRINKDLLDDALKPQSPDPTLDFAPSMSSPDQSYASVHMHNMVTTPASATSRESPSMGAGEVYMVHTLQRLWDDYRQRTKLERTIPRPLQLERARSLLEQFLAYLFWTDEFITDEEANLSILDTLYCFMHDRYLVEDIMFMAAHDFLSSVTEYSGMDKMIQLLGHVFVGNLDASCLRYVLLMSEFISAVDWKEVEDFRAFTSVVYPFLNEDDLESLQMSYTSYSENRVSRQLVSSFIIHIILKYREPRFHDLENKLVPYQSSESGQLTEREFREALDSLLPLSNERVRRRLFMQSERAVRW--DGVLNGVPIMRLAQISGYLAL 779
[Close]
BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. TrEMBL
Match: A0A3M6TKQ9 (Uncharacterized protein OS=Pocillopora damicornis OX=46731 GN=pdam_00001341 PE=4 SV=1)

HSP 1 Score: 243.817 bits (621), Expect = 1.277e-64
Identity = 201/778 (25.84%), Postives = 370/778 (47.56%), Query Frame = 2 
Query:  248 LCVENIIHCLELFENVVEFLGIFKEIMKEIKDDLTEAIFSRTLTVTE----KDSLERIERIPYFELCRQSLEIQEVKSLEFQKINDTFTKECCRLENEL----KLLNDINK---------------------EKENQCLEYKREIFXXXXXXXXXXXXXXSMQEEKLEMTKSTQNIFEKIDEENIILKNEINRQKAIIDDLKHFKESHEHLNKSFEQACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDFD---KRIMGFKEKMMSCINDGDN-----EDNDQFIVTSILEMQNNKLHFK-------NEFSLVQIESLMLQNHQAVLINDWSVIE-ESEAKKE------------------------LTFVKDIKSSFTID-----NRILNKYSVLIYIS-NDGESFYECKEVRFCESCGNRSVFCPHTYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIEEKLQINSNEERXXXXXXXXXXXXXXTDTETIISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLFKELA--IFYTDDGFQEIAPFSRITEIVAFLSFLE 2350
            L  E +  C  +++ ++  LG++K+++K ++D+L EA++S   T       K     I+RIPYF L  +  E       E  K  D   +    LEN+L    + L + NK                     E ENQ LE ++                 S+Q E++ M ++ ++ +EK       LK ++ + K     L+ FKE ++ L ++F  +   F+++   +   +  ++A L  EI     +  +L  ++N+++++++   +       + +   + G N     +D  +  V    E+   K  FK       NEF L++I+   L++  A L  +   IE E+  KKE                        + FVK + S+   D      RIL+KYS ++Y S N G++++E K+ +FC SCG  ++ CPH     KV+ LP   TH+KI  P + I+ +     +     E    +   SN           K     T T     ++ L +D+ +RT I+R   R   + ++ S+IE F++++I +D+Y +   ++ +++D LY FF +RY       L+++DFF ++I+ AS ++ IQLF   + G++D   +RY+  + + +  V+W + +D+R F  +V+PF+NE+D++   + Y SFSEN   K  + ++F+Y  LK R+PRF  +  + +    + PGF T  E+   ++++  L ++++  RLF E    +   DD    +    R+ +I  +L+ L+
Sbjct:   30 LSEERMTTCFHVYDELIPELGVYKKVLKMLRDELYEAVYSNEYTTATPKKGKSKTTYIQRIPYFVLVNRVFE-------ERDKNADQLKEAINALENKLAEKDQQLEEANKTIEQLKKSLKECSDKIYNMEIEMENQNLEQRK--------------LETSVQYEQM-MQQAAKDRYEK---RISGLKEDLTQAKERNKFLEKFKEGYDALEEAFNDST-VFDNKP--QKPAVLTRRAQLIQEISNAKLLEEQLLTMQNLVIEEYELFLEENKALPTEEVDLKSSGSNFRATPDDEHEMRVKLEEELHKVKERFKKSIADIENEFQLIEIQRSSLEDQLAELEEEAKRIERETNEKKERKKSMFFMEGEKERKPDTPEDDDEIDFVKIMNSAHNQDPFISHERILSKYSAMMYYSCNQGKNYHEFKDAKFCASCGETTLLCPHKVTDHKVVSLPHNCTHIKIIRPTVHISREEKPPVLVTETPESVRAMSAISNSTVTYGEESILKEQQHLTTT-----YKFLWDDYYSRTSIRRQIPRALSQDRVSSIIEQFYSSLIWQDDYAVEDEQIVSVVDTLYSFFHERYLVPDVTFLAVFDFFTSVIKFASGNKNIQLFAQAMCGSLDPVVVRYILLINEFIDLVEWLAVKDIRIFAQVVYPFMNEEDIEQFSMGYTSFSENKISKELVSEYFLYIILKYREPRFQEMEVKLLQQPGRRPGFMTDIEYAEAIDNICPLASERMRRRLFVESVEHLRTADDSVSVM----RLAQITGYLTLLQ 770
[Close]
BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. TrEMBL
Match: A0A2T7PA42 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_09547 PE=4 SV=1)

HSP 1 Score: 236.113 bits (601), Expect = 1.123e-61
Identity = 204/778 (26.22%), Postives = 373/778 (47.94%), Query Frame = 2 
Query:  236 NGTYLCVENIIHCLELFENVVEFLGIFKEIMKEIKDDLTEAIFSRTLT-VTEKDSLER-------IERIPYFELCRQSLEIQEVKSLEFQKINDTFTK--------------ECCRLENELKLLNDINKEKENQCLEYKREIFXXXXXXXXXXXXXXSMQEE--------KLEMTKSTQNI-----FEK---------------IDEENIILKNE----INRQKAIIDDLKHFKESHEHLNKSFEQACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDFDKRI----MGFKEKMMSCINDGD---NEDNDQFIVTSILEMQNNKLHFKNEFSLVQIESLMLQNHQAVLINDWSVIEESEAKKELTFVKDIKSSFTIDNRILNKYSVLIYISND-GESFYECKEVRFCESCGNRSVFCPH-TYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIEEKLQ--INSNEERXXXXXXXXXXXXXXTDTET----------IISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLFKELAIFYTDDGFQEIAPFSRITEIVAFLSF 2344
              T L  E ++   ++ + ++  LG++  I  ++++DL +A++S  LT V E+ +  +       I+R+PYF L +++ + Q  +  E ++  D   K              +  +L+ ++  LN +  E +    E   EI +  Q + +     ++MQ +        K  + ++ Q I     F+K                DE+N   KN      ++++ +I D+       E +      A E F+    +E+    HK+A LE ++ T    ++E+D L+ + LDD D+ +    + F+  + + +++ D     +N       +LE  N  L        V+  S   +N++++L   W+ ++E + K       +    +   +R+ +KY+ ++Y SN+ G++F E K+ ++C SCG ++V CPH     EKV  LP   TH+KI  P++R+N +  +  V  P  E+   ++  ++S  +  Q +     +    T  E+          + SF+ + +D+  RT + RT  R   + Q +S+ E+F A II +DE    +    +ILD LY F   RY  +    +  +DF ++II+ +   + I+L  HVLVGN+D+S +RY+  + D +  VDW   ED R F S+V+PFL EDD++++ +SYISFSEN   K  +  F I+  LK R+PRF  + ++ +  +    G  T  E +  ++S+  L N+ +  RLF E       D      P  R+ +I  +L+ 
Sbjct:   53 GATGLTEERMVLAFQVLDELIPQLGLYSRIFTKLREDLFKAVYSGELTGVVEEGTDNKSVCGESYIQRLPYFVLVKRTHDKQNEQIEELKEQLDIVKKRLFDKHKQFEESQEKTAKLQEQIDHLNKVENELQQIISEKDAEICRIGQEMEKNWNNAENMQHQLECDIADLKDSLIEAKQEIEYLSQFKKGYDDMYYAFTDKDQESDEDNSAKKNPQTIIASKREYLIGDVHSANHMEEQILSVMNTAMEEFDK--FLES----HKQA-LEEKVITADMTDAEMD-LQEMELDDADQELEVVQLRFESTIRAMLSELDLLHKHNNMMMEQLQMLEETNPSLAKNKNVEHVKFSSG--KNNESIL---WAGLDEDDGKH------NTADPYIPQDRVFSKYAAMLYTSNNSGKTFEEFKDAKYCSSCGEKTVICPHKAGGTEKVFVLPHNCTHLKISRPKVRVNRELVQMLVKPPSPELTLNVEPVLSSAVQSYQPAHNMSLTPDTVTSQESPSYSMGEAYMVNSFQRVWDDYHIRTDLSRTIPRPLTQEQTVSLFEEFLAYIILQDET-AGEKLCFSILDNLYNFMKWRYLLDDIMYMMTHDFLSSIIKYSGADKMIELLDHVLVGNLDASCLRYVMLIADFIKMVDWMEVEDFRAFASLVYPFLTEDDLETLQMSYISFSENHISKQLVCSFIIHIILKYREPRFHDLENKLLPFQISESGHLTDKEHKDAMDSIVPLCNEHMRRRLFLEAEKAVAHDSISNAVPVMRLAQITGYLAL 810
[Close]
BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. TrEMBL
Match: A0A2B4SZG9 (Exonuclease 3'-5' domain-containing protein 1 OS=Stylophora pistillata OX=50429 GN=Exd1 PE=4 SV=1)

HSP 1 Score: 239.58 bits (610), Expect = 1.175e-61
Identity = 202/761 (26.54%), Postives = 371/761 (48.75%), Query Frame = 2 
Query:  248 LCVENIIHCLELFENVVEFLGIFKEIMKEIKDDLTEAIFSRTLTVT----EKDSLERIERIPYFELCRQSLEIQEVKSLEFQKINDTFTKECCRLENEL----KLLNDINK--EKENQCLEYKREIFXXXXXXXXXXXXXXSMQEEKLEMTKSTQNIFEKIDEENII-LKNEINRQKAIIDDLKHFKESHEHLNKSFEQACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDF------DKRIMGFKEKMMSCIND---GDNEDNDQFIVTSILEMQNNKLHFK-------NEFSLVQIESLMLQNHQAVLINDWSVI-----EESEAKKEL--------------------TFVKDIKSSFTIDN-----RILNKYSVLIYIS-NDGESFYECKEVRFCESCGNRSVFCPHTYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIEEKLQINSNEERXXXXXXXXXXXXXXTDTETIISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLFKELA--IFYTDDGFQEIAPFSRITEIVAFLSFLE 2350
            L  E +  C  +++ ++  LG++K+++K ++D+L EA++S   T       K     I+RIPYF L  +  E +++ +       D   +    LEN+L    KLL + N+  E+  + L+  R+   N++   + Q   Q   E  ++  + TQ   +   E+ I  LK E+ + K     L+ FKE ++ L ++F  +   FE++   +   +  ++A L  EI     +  +L  ++N+++++F      +K +   +E  +        G  +D  +  V    E+   K  FK       NEF L++I+   L++    L  +   I     E+ E KK +                     FVK + S+   D      RIL+KYS ++Y S N G++++  K+ +FC SCG  ++ CPH     KV+ LP   TH+KI  P + I+       +     E    + + SN           K     T T     ++ L +D+ +RT I+R   R   + ++ S+IE F++++I +D+Y +   ++ ++LD LY FF +RY       L++YDFF ++I+ A  ++ IQLF   + G++D   +RY+  + + +  V+W + +D+R F  +V+PF+NE+D++   + Y SFSEN   K  + ++F+Y  LK R+PRF  +  + +    + PGF T  E+   ++++  L ++++  RLF E    +  TDD    +    R+ +I  +L+ L+
Sbjct:   30 LTEERMTTCFHVYDELIPELGVYKKVLKMLRDELYEAVYSNEYTTAIPKKGKSKTTYIQRIPYFVLVNRVYEERDINA-------DQLKENIAALENKLAEKDKLLEEANESIERLKKSLKECRDKIYNMEIEMENQNLEQRKLEASVQYEQMTQQAAKDRYEKRISGLKEELAQAKERNKFLEKFKEGYDTLEEAFNDST-VFENKP--QNPAVLTRRAQLIQEISNAKLLEEQLLTMQNLVIEEFELFLEENKALPTTEEVDLGSSGSNFRGTPDDEHEMRVKLEEELHKVKERFKQSIADIENEFQLIEIQRSSLEDQLVELEEEARRIERETNEKKERKKSMFFMEGEKEKKPDPPEDDDEIDFVKIMNSAHNQDPFISHERILSKYSAMMYYSCNQGKNYHVFKDAKFCASCGETTLLCPHKITDHKVVSLPHNCTHVKIIRPTVHISRDEKPPVLVTETPESVRAISVISNSTLAYGEESILKEQQHLTTT-----YKFLWDDYYSRTSIRRQIPRALSQDRVSSIIEQFYSSLIWQDDYAVEDEQIVSVLDTLYSFFHERYLVSDVTFLAVYDFFTSVIKFAPNNKNIQLFAQAMCGSLDPVVVRYILLVNEFIDLVEWVAVKDIRIFAQVVYPFMNEEDIEQFSMGYTSFSENKISKELVSEYFLYIILKYREPRFQEMEVKLLQQPGRRPGFMTDIEYAEAIDNICPLASERMRRRLFVESVEHLRATDDSVSVM----RLAQITGYLTILQ 771
[Close]
BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. TrEMBL
Match: A0A210Q1W3 (Uncharacterized protein OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT17012 PE=4 SV=1)

HSP 1 Score: 235.343 bits (599), Expect = 2.056e-61
Identity = 205/804 (25.50%), Postives = 374/804 (46.52%), Query Frame = 2 
Query:  278 ELFENVVEFLGIFKEIMKEIKDDLTEAIFSRTLTVTEKDSLERIERIPYFELCR--------------QSLEIQEVKSLEFQKINDTFTKECCRLENELKLLNDINKEKENQCLEYKREIFXXXXXXXXXXXXXXSMQEEKLEMTKSTQNIFEKIDEENIILKNEINRQKAIIDDLKHFKESHEHLNKSFEQACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDFDKRIMGFKEKMMSCINDGDNEDNDQFIVTSI-LEMQNNKL-----HFKNEFSLVQIESLMLQNHQAVLINDWSVIEESEA-----KKELTFVKDI---------------------------KSSFTIDNRILNKYSVLIYISND-GESFYECKEVRFCESCGNRSVFCPHTYQK-EKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIE---EKLQINSNEERXXXXXXXXXXXXXXTDTETIISFES--------LLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATII----NEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFN--EFQILLESLTSLPNKKLSIRLFKELAIFYTDDGFQEIAPFSRITEIVAFLSFLESVEKSKEILREKYKCKNIKNKNSNGQLKWSFFQLTQLASKLL 2476
            ++ ++++  LG++  I  +++DDL  +++S  LT  +  S   I +IPY+   R              + L+I + +  E  K  +   ++   LE  +        E+ NQ L     +  +  +      E  + ++EK E T++      ++D +   L+  +      I+ L  +K+ ++ L  +F    E  +         +  K+ANL T I+    +  ++  + N  +++FDK +   KE++   I   D+  N +F V  + +E  + +L      F+N    +  E  +L+ H  +L+     +E+++       +E +   D                               F    R+  KY+ ++Y SN+  +SF E K+ +FC SCG ++V CPH     +KVI LP  +TH+KI  P++RIN +     +     E+         + +  R  SS  + ++   S ++ +++  E+        L +D+++RT ++R   R+    + LS +E FWA +I    N DE D+H S     LD +YL+  +RY  E    L  +DF +++ E  + ++ + +F H+L GN+D +  RY   + D + AV+WK  ED R F S+V+PFL EDDV+++ +SY SFSEN   +  + QF ++  LK R+P F  +  + +  +TQ  G  T N  EF+  ++++  L + KL  RLF E       DGFQ   P  R+++I  +L  L+    ++E +  K      +  +S  + K    QL +    L+
Sbjct:   46 QVLDDLIPKLGVYTRIFAKVRDDLYASVYSENLTAHKDGS---IAQIPYYTQVRRIHDEHDDKLDVVTEQLDIVKQRLFEKHKQLEDSQQKGAMLEERI--------EEMNQRLVMVDSMLTDKTSDIVRLEEELAEEQEKGEQTQA------RLDGDVDDLRESLEEAHGEIEYLSRYKKGYDDLYNAFLDQPEIDDLPKKNLRPVISTKRANLMTNIEAAQRLEEQIMSVMNTAVEEFDKFLEEHKEELQK-IEIRDDLTNAEFEVQEMDIEQADQELEAMQDRFRNTVGDISNELQLLKQHGTMLMEQLQTLEQNKPTLVKRNRERSKFSDTNIQPGLGKSDSILSVGLQDTEADEEGDADPFIPQERVFAKYAAMLYTSNNMSKSFEEFKDAKFCSSCGEKTVICPHKLPGVDKVIVLPHNTTHIKITRPKVRINKELIDEMMKPRSPELSFDMPSTAASYSRPRMDSSVMTIQTPATSRESPSLVGSEAHMQHTMHRLFDDYKDRTHLERNIPRQLSLERTLSQVEQFWAYMIWTDENGDENDLHHS----TLDHVYLYMRERYIIEDIMFLCAHDFLSSVAESGAINKTVHVFGHILAGNLDGAVFRYAMLMSDFIQAVEWKEVEDFRAFASVVYPFLGEDDVETLQMSYTSFSENRISEQLVCQFLMHLILKYREPCFQEMEHKILPFQTQESGQPTLNDKEFKEAIDAVVPLASDKLRNRLFYESEKAVRIDGFQGKVPIMRLSQICGYLYLLQIANVTRENVANKVIQWRERPHSSGSEKKTHELQLVETDEPLI 827
[Close]
BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO46114 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR69])

HSP 1 Score: 231.491 bits (589), Expect = 3.915e-64
Identity = 193/805 (23.98%), Postives = 386/805 (47.95%), Query Frame = 2 
Query:  251 CVENIIHCLELFENVVEFLGIFKEIMKEIKDDLTEAIFSRT-LTVTEKDSLER---IERIPYFELCRQSLEIQEVKSLEFQKINDTFTKECCRLENELKLLNDINKEKENQCLEYKREIFXXXXXXXXXXXXXXSMQEEKLEMTKSTQNIFEKIDEENII-LKNEINRQKAIIDDLKHFKESHEHLNKSFEQACENFEDEDTIETGHL---FHKKANLETEIKTITTMNSELDYLENVMLDDFDKRIMGFK---------EKMMSCIN-----DGDNEDNDQFIVTSILEMQNNKLHFKNEFSLVQIESLMLQNHQAVLINDWSVIE-ESEAKKELT--------------------------FVKDIKSSFTIDN-----RILNKYSVLIYIS-NDGESFYECKEVRFCESCGNRSVFCPHTYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIEEKLQINSNEERXXXXXXXXXXXXXXTDTETIISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLFKELAIFYTDDGFQEIAPFSRITEIVAFLSFLESVEKSKEILREKYKCKNIKNKNSNGQLKWSFFQLTQLASKLLRNG*FSIK 2500
            C E +  C  + + ++  LG++++IM  ++D+L EA+ S+   T+  K    R   ++RIPYF L  +  E ++ ++ + Q+  +   K     + EL    +   +   +  E + EIF     +     E+  ++ + LE  + +  + ++  E+ I  LK+++ + + ++  L+ +K+ ++ L ++F  +         ++  H      K+A +  EI +   +  +L  +ENV+++++D  +   K         E   S  N     D ++E+  +++  +  +M+N    +K   + ++ E  +++ H++ L +  S  + E E + E+                           FVK + +    D      RIL+KY+ ++Y S N G++F+E K+ +FC SCG  ++ CPH    EK+I LP  STH+KI  P + I  +  K  ++ P      +L   S         +    +     T    S++ L +D   RT ++R   R   + ++LS+I  F++T+I +D+Y + +  V +IL+ ++ FF DRY     A L+++DF + +++ A     I+LF   + G++D   +RY+  +   +  VDW + ED+RTF   V+PF++E+D++   + Y SFSEN      + ++ +Y  LK R+PRF  +  + +      PGF T  EF   ++++  L ++++  RLF E ++ +  D    +    R+++I  +L+ ++       I+R+    K ++ +      K      T    +LLR    ++K
Sbjct:   33 CDERMPICFNVLDEILPQLGVYRKIMSMLRDELYEAVHSQEYTTIPPKKGRNRTPILQRIPYFVLVNRVYEERDKRADDLQEDIERLRKNMESTQVELNAAKEQVSQLTQKVRENEDEIFNLKMELQNSDLEMNKIRLD-LEQEQRSHALTKERYEKRITNLKDQLEKCEKMVKFLRRYKDGYDDLEEAFNDSTV------FVKRPHKPVKLTKRAQMVQEIASAKQLEQQLLEMENVIIEEYDTFLEENKVKPDNNNELEPGQSQTNFTQKWDDESEEMKRYL-KAQQDMENR---YKKSIADIKKELQLIEVHKSALEDQLSHQDAEHEMRDEMPKRRTSFLDKRPEAAAKSDDDDDDDIDFVKIMSTPGQADPFIPHERILSKYAAMMYYSCNHGKNFHEFKDAKFCPSCGESTLLCPHKVVDEKIISLPHNSTHIKILRPAVHI-LQGDKRPISAPGTPDSMRLMSASGSATPSYGDEHVVRAQQRLTT----SYKRLWDDLAARTDVRRLLPRPISKERVLSIITQFYSTLIWQDDYAMEEEHVVSILETMHTFFQDRYIVPNVAYLAMHDFISGVVKYAQECRSIELFAQAMCGSLDPVVIRYVLLINYVIELVDWAAVEDIRTFAQCVYPFMHEEDLEQFTMGYTSFSENKISNQLVSEYLLYIILKYREPRFQDMEVKLLSHPGHRPGFMTDIEFTEAIDNICPLASERMRRRLFAE-SVEHIQDSEDSVN-VMRLSQITGYLALMQIT----NIIRDSVADKVVQARAKQSDEKSPSLSSTMTKQQLLRVAEATMK 815
[Close]
BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000036160.1 (SMESG000036160.1)

HSP 1 Score: 1485.7 bits (3845), Expect = 0.000e+0
Identity = 772/786 (98.22%), Postives = 772/786 (98.22%), Query Frame = 2 
Query:  128 MQSERKLWGIYLNLIFFDNPLDQISKYRSSTNDSRLNGTYLCVENIIHCLELFENVVEFLGIFKEIMKEIKDDLTEAIFSRTLTVTEKDSLERIERIPYFELCRQSLEIQEVKSLEFQKINDTFTKECCRLENELKLLNDINKEKENQCLEYKREIFXXXXXXXXXXXXXXSMQEEKLEMTKSTQNIFEKIDEENIILKNEINRQKAIIDDLKHFKESHEHLNKSFEQACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDFDKRIMGFKEKMMSCINDGDNEDNDQFIVTSILEMQNNKLHFKNEFSLVQIESLMLQNHQAVLINDWSVIEESEAKKELTFVKDIKSSFTIDNRILNKYSVLIYISNDGESFYECKEVRFCESCGNRSVFCPHTYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIEEKLQINSNEERXXXXXXXXXXXXXXTDTETIISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLFKELAIFYTDDGFQEIAPFSRITEIVAFLSFLESVEKSKEILREKYKCKNIKNKNSNGQLKWSFFQLTQLASKLLRNG 2485
            MQSERKLW             DQISKYRSSTNDSRLNGTYLCVENIIHCLELFENVVEFLGIFKEIMKEIKDDLTEAIFSRTLTVTEKDSLERIERIPYFELCRQSLEIQEVKSLEFQKINDTFTKECCRLENELKLLNDINKEKENQCLEYKREIFQNLQNINQIQREIQSMQEEKLEMTKSTQNIFEKIDEENIILKNEINRQKAIIDDLKHFKESHEHLNKSF QACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDFDKRIMGFKEKMMSCINDGDNEDNDQFIVTSILEMQNNKLHFKNEFSLVQIESLMLQNHQAVLINDWSVIEESEAKKELTFVKDIKSSFTIDNRILNKYSVLIYISNDGESFYECKEVRFCESCGNRSVFCPHTYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIEEKLQINSNEERKQSSRKSFKSSMASTDTETIISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLFKELAIFYTDDGFQEIAPFSRITEIVAFLSFLESVEKSKEILREKYKCKNIKNKNSNGQLKWSFFQLTQLASKLLRNG
Sbjct:    1 MQSERKLW-------------DQISKYRSSTNDSRLNGTYLCVENIIHCLELFENVVEFLGIFKEIMKEIKDDLTEAIFSRTLTVTEKDSLERIERIPYFELCRQSLEIQEVKSLEFQKINDTFTKECCRLENELKLLNDINKEKENQCLEYKREIFQNLQNINQIQREIQSMQEEKLEMTKSTQNIFEKIDEENIILKNEINRQKAIIDDLKHFKESHEHLNKSFVQACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDFDKRIMGFKEKMMSCINDGDNEDNDQFIVTSILEMQNNKLHFKNEFSLVQIESLMLQNHQAVLINDWSVIEESEAKKELTFVKDIKSSFTIDNRILNKYSVLIYISNDGESFYECKEVRFCESCGNRSVFCPHTYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIEEKLQINSNEERKQSSRKSFKSSMASTDTETIISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLFKELAIFYTDDGFQEIAPFSRITEIVAFLSFLESVEKSKEILREKYKCKNIKNKNSNGQLKWSFFQLTQLASKLLRNG 773
[Close]
BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000036160.1 (SMESG000036160.1)

HSP 1 Score: 1446.03 bits (3742), Expect = 0.000e+0
Identity = 757/786 (96.31%), Postives = 757/786 (96.31%), Query Frame = 2 
Query:  128 MQSERKLWGIYLNLIFFDNPLDQISKYRSSTNDSRLNGTYLCVENIIHCLELFENVVEFLGIFKEIMKEIKDDLTEAIFSRTLTVTEKDSLERIERIPYFELCRQSLEIQEVKSLEFQKINDTFTKECCRLENELKLLNDINKEKENQCLEYKREIFXXXXXXXXXXXXXXSMQEEKLEMTKSTQNIFEKIDEENIILKNEINRQKAIIDDLKHFKESHEHLNKSFEQACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDFDKRIMGFKEKMMSCINDGDNEDNDQFIVTSILEMQNNKLHFKNEFSLVQIESLMLQNHQAVLINDWSVIEESEAKKELTFVKDIKSSFTIDNRILNKYSVLIYISNDGESFYECKEVRFCESCGNRSVFCPHTYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIEEKLQINSNEERXXXXXXXXXXXXXXTDTETIISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLFKELAIFYTDDGFQEIAPFSRITEIVAFLSFLESVEKSKEILREKYKCKNIKNKNSNGQLKWSFFQLTQLASKLLRNG 2485
            MQSERKLW             DQISKYRSSTNDSRLNGTYLCVENIIHCLELFENVVEFL               EAIFSRTLTVTEKDSLERIERIPYFELCRQSLEIQEVKSLEFQKINDTFTKECCRLENELKLLNDINKEKENQCLEYKREIFQNLQNINQIQREIQSMQEEKLEMTKSTQNIFEKIDEENIILKNEINRQKAIIDDLKHFKESHEHLNKSF QACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDFDKRIMGFKEKMMSCINDGDNEDNDQFIVTSILEMQNNKLHFKNEFSLVQIESLMLQNHQAVLINDWSVIEESEAKKELTFVKDIKSSFTIDNRILNKYSVLIYISNDGESFYECKEVRFCESCGNRSVFCPHTYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIEEKLQINSNEERKQSSRKSFKSSMASTDTETIISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLFKELAIFYTDDGFQEIAPFSRITEIVAFLSFLESVEKSKEILREKYKCKNIKNKNSNGQLKWSFFQLTQLASKLLRNG
Sbjct:    1 MQSERKLW-------------DQISKYRSSTNDSRLNGTYLCVENIIHCLELFENVVEFL---------------EAIFSRTLTVTEKDSLERIERIPYFELCRQSLEIQEVKSLEFQKINDTFTKECCRLENELKLLNDINKEKENQCLEYKREIFQNLQNINQIQREIQSMQEEKLEMTKSTQNIFEKIDEENIILKNEINRQKAIIDDLKHFKESHEHLNKSFVQACENFEDEDTIETGHLFHKKANLETEIKTITTMNSELDYLENVMLDDFDKRIMGFKEKMMSCINDGDNEDNDQFIVTSILEMQNNKLHFKNEFSLVQIESLMLQNHQAVLINDWSVIEESEAKKELTFVKDIKSSFTIDNRILNKYSVLIYISNDGESFYECKEVRFCESCGNRSVFCPHTYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEIEEKLQINSNEERKQSSRKSFKSSMASTDTETIISFESLLEDFENRTQIKRTNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRYAHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLVDCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRIFQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLPNKKLSIRLFKELAIFYTDDGFQEIAPFSRITEIVAFLSFLESVEKSKEILREKYKCKNIKNKNSNGQLKWSFFQLTQLASKLLRNG 758
The following BLAST results are available for this feature:
BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A433U4P32.187e-6625.86Uncharacterized protein OS=Elysia chlorotica OX=18... [more]
A0A3M6TKQ91.277e-6425.84Uncharacterized protein OS=Pocillopora damicornis ... [more]
A0A2T7PA421.123e-6126.22Uncharacterized protein OS=Pomacea canaliculata OX... [more]
A0A2B4SZG91.175e-6126.54Exonuclease 3'-5' domain-containing protein 1 OS=S... [more]
A0A210Q1W32.056e-6125.50Uncharacterized protein OS=Mizuhopecten yessoensis... [more]
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO461143.915e-6423.98Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Exonuclease 3'-5' domain-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000036160.10.000e+098.22SMESG000036160.1[more]
SMESG000036160.10.000e+096.31SMESG000036160.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026777 ID=SMED30026777|Name=Exonuclease 3'-5' domain-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2692bp
CTTGGTACTAAATTTATAACTATATAAATTTTATTTAATGTTTTAAAATA
AAGTTATTCCAAGTTATTAATTTAGATTGAACATTGTTTGCATATTTACT
TTTCCAACTTTGTATTATTTAATTTGAATGCAGTCAGAAAGAAAATTATG
GGGTATTTATTTAAATTTAATTTTTTTTGACAATCCATTAGATCAAATTT
CCAAATACCGATCTTCAACAAATGATTCTAGATTAAACGGAACGTATTTG
TGTGTTGAAAATATTATTCATTGCCTAGAATTATTTGAAAATGTAGTAGA
ATTTCTAGGTATTTTTAAAGAAATTATGAAGGAAATAAAAGACGATTTAA
CAGAAGCAATATTTAGTCGTACTTTGACTGTTACTGAAAAAGATAGTTTA
GAAAGAATAGAGCGAATACCTTATTTTGAATTATGTAGACAGTCGTTAGA
AATACAAGAAGTAAAATCTTTGGAATTTCAAAAAATTAATGACACTTTTA
CGAAAGAATGTTGTCGTTTGGAAAACGAGTTAAAGCTATTAAATGATATC
AATAAAGAAAAAGAAAACCAATGCTTAGAATATAAACGAGAAATATTTCA
AAATTTACAAAATATAAATCAGATACAAAGAGAGATACAAAGCATGCAAG
AAGAAAAACTAGAAATGACCAAAAGTACACAAAATATATTTGAAAAAATT
GATGAAGAAAATATTATTTTAAAGAATGAAATTAATCGACAAAAGGCTAT
TATAGACGATCTGAAACATTTCAAAGAGTCACATGAACATTTAAATAAAA
GTTTCGAACAAGCATGTGAAAATTTTGAAGATGAAGATACTATCGAAACA
GGACATTTATTCCATAAAAAAGCAAATCTTGAAACGGAAATCAAAACTAT
CACCACAATGAACAGTGAACTTGATTATTTAGAAAACGTTATGCTTGACG
ATTTCGATAAAAGGATTATGGGGTTTAAGGAGAAAATGATGAGCTGCATC
AATGATGGTGACAATGAAGATAATGACCAATTTATAGTCACATCCATATT
AGAAATGCAAAATAATAAATTGCATTTTAAAAACGAATTTTCTCTAGTGC
AAATAGAATCTTTGATGCTTCAAAATCACCAAGCTGTTCTAATTAATGAC
TGGTCAGTCATCGAAGAATCCGAAGCGAAAAAGGAATTGACTTTTGTCAA
AGATATAAAATCTAGTTTTACGATTGACAATAGGATTTTGAATAAATATT
CGGTACTAATTTATATTTCTAATGACGGAGAAAGCTTCTATGAATGCAAA
GAAGTGCGATTCTGTGAATCTTGTGGAAATAGAAGTGTATTTTGTCCTCA
TACATATCAAAAAGAAAAAGTTATTAAGCTACCTGTTGGATCCACTCATA
TGAAAATCCAACATCCAGAAATTAGAATCAACTCAAAGTACGCCAAATTT
TTTGTAACAAAACCATTTTTCGAAATCGAAGAGAAATTACAAATAAATTC
CAATGAAGAAAGGAAACAATCATCTAGAAAATCATTTAAAAGTTCCATGG
CCAGTACTGACACAGAAACAATTATTTCTTTTGAATCTTTATTGGAAGAC
TTTGAAAATCGAACACAAATCAAAAGAACTAATTATCGAAAGTTTGATGA
ATTTCAAATATTATCAGTAATTGAAGACTTCTGGGCTACAATAATAAATG
AAGATGAGTACGACATTCATCAATCTGAAGTTACCACGATTCTGGACAAA
TTGTATTTATTTTTTTTTGATCGGTATGCTCATGAAAAGGCAGCCCTGCT
TTCCATTTATGATTTTTTTGCCAATATTATTGAAATGGCTTCTTATTCCG
AATTTATTCAACTGTTCTGCCACGTTTTAGTGGGTAACATTGACAGTTCA
ACAATGAGATATTTGTTTCATTTGGTTGATTGCCTCGCAGCTGTGGACTG
GAAATCTGAAGAAGATCTAAGAACATTTCTTTCAATCGTTCATCCATTTC
TTAATGAAGACGATGTCGATAGTGTGGTTTTATCCTATATTTCATTTTCG
GAAAATGTTTTTGAAAAATCGCGAATTTTTCAATTTTTTATTTATAACTT
TTTGAAAAAACGAGATCCAAGATTCAGTTTAGTCAGGAGTGAAGGAGTTG
ATATGAAGACACAAATTCCTGGATTTTATACATTTAATGAATTTCAGATT
TTATTAGAATCATTGACTTCGTTGCCAAACAAAAAATTAAGCATCCGACT
TTTTAAGGAACTGGCTATTTTCTATACCGATGATGGTTTTCAAGAAATTG
CACCTTTTTCAAGAATTACTGAAATCGTTGCATTTCTATCCTTTTTGGAA
TCAGTGGAAAAATCGAAAGAAATTCTCCGTGAAAAATATAAATGCAAAAA
TATAAAGAATAAAAACTCAAATGGACAATTGAAATGGAGTTTTTTTCAAT
TAACACAATTAGCATCAAAACTTTTACGAAATGGCTAATTTTCAATCAAA
TATTCTAAGAAAATATTTTGACATATTCAAAGGAAATAAATATGTTTAAT
AAGTTTTAAATTTTGTAGCTCGTTTGTATTTTACTAAATAATAGTTAGTG
TAGCTCTCAGTTATATATGGGCTTCGGCATGTTTTATGGAGTCTGTATGT
ATTCAAATTAAAAAAATATATTTTGAGTTTTTTAAAAAAAAA
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protein sequence of SMED30026777-orf-1

>SMED30026777-orf-1 ID=SMED30026777-orf-1|Name=SMED30026777-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=787bp
MQSERKLWGIYLNLIFFDNPLDQISKYRSSTNDSRLNGTYLCVENIIHCL
ELFENVVEFLGIFKEIMKEIKDDLTEAIFSRTLTVTEKDSLERIERIPYF
ELCRQSLEIQEVKSLEFQKINDTFTKECCRLENELKLLNDINKEKENQCL
EYKREIFQNLQNINQIQREIQSMQEEKLEMTKSTQNIFEKIDEENIILKN
EINRQKAIIDDLKHFKESHEHLNKSFEQACENFEDEDTIETGHLFHKKAN
LETEIKTITTMNSELDYLENVMLDDFDKRIMGFKEKMMSCINDGDNEDND
QFIVTSILEMQNNKLHFKNEFSLVQIESLMLQNHQAVLINDWSVIEESEA
KKELTFVKDIKSSFTIDNRILNKYSVLIYISNDGESFYECKEVRFCESCG
NRSVFCPHTYQKEKVIKLPVGSTHMKIQHPEIRINSKYAKFFVTKPFFEI
EEKLQINSNEERKQSSRKSFKSSMASTDTETIISFESLLEDFENRTQIKR
TNYRKFDEFQILSVIEDFWATIINEDEYDIHQSEVTTILDKLYLFFFDRY
AHEKAALLSIYDFFANIIEMASYSEFIQLFCHVLVGNIDSSTMRYLFHLV
DCLAAVDWKSEEDLRTFLSIVHPFLNEDDVDSVVLSYISFSENVFEKSRI
FQFFIYNFLKKRDPRFSLVRSEGVDMKTQIPGFYTFNEFQILLESLTSLP
NKKLSIRLFKELAIFYTDDGFQEIAPFSRITEIVAFLSFLESVEKSKEIL
REKYKCKNIKNKNSNGQLKWSFFQLTQLASKLLRNG*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0004527exonuclease activity
GO:00084083'-5' exonuclease activity
Vocabulary: biological process
TermDefinition
GO:0006139nucleobase-containing compound metabolic process
GO:0090305nucleic acid phosphodiester bond hydrolysis
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 135..183