cAMP dependent protein kinase catalytic subunit
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppSub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30026769 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 397.127 bits (1019), Expect = 3.151e-136 Identity = 191/323 (59.13%), Postives = 251/323 (77.71%), Query Frame = 3
Query: 126 TDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
+D L K E+FL KW++P + TA ++ FERIKTLG G+FGRV+LVKHK GN+YA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L +SFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y +K +AP+ PK KGP DTS FD +EEE
Sbjct: 6 SDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEE 326
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 397.127 bits (1019), Expect = 3.151e-136 Identity = 191/323 (59.13%), Postives = 251/323 (77.71%), Query Frame = 3
Query: 126 TDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
+D L K E+FL KW++P + TA ++ FERIKTLG G+FGRV+LVKHK GN+YA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L +SFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y +K +AP+ PK KGP DTS FD +EEE
Sbjct: 6 SDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEE 326
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 396.741 bits (1018), Expect = 5.735e-136 Identity = 191/326 (58.59%), Postives = 252/326 (77.30%), Query Frame = 3
Query: 117 VSMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
+S+ +F L K E+FL KW+NP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 18 ISVKEF---LAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 338
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 396.356 bits (1017), Expect = 8.901e-136 Identity = 189/317 (59.62%), Postives = 247/317 (77.92%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 20 LAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 397.897 bits (1021), Expect = 9.831e-136 Identity = 192/325 (59.08%), Postives = 251/325 (77.23%), Query Frame = 3
Query: 120 SMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
SM +F L K E+FL KW+NP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 62 SMKEF---LAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 381
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 400.593 bits (1028), Expect = 2.495e-137 Identity = 194/324 (59.88%), Postives = 256/324 (79.01%), Query Frame = 3
Query: 123 MTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
+ DF L K E+F +W+NP + TA ++DF+RIKTLG G+FGRV+LVKHK +GNYYA+K+L K +++K KQ+E+ LNEK+IL I+FPFL+ + +SFKDNS LYMVLEF+ GGEMF+ LR + RF + +FY AQ+++AFEYLH L + YRDLKPEN+L++S GYLK+ D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKVKF S FS +LKDL++NL+QVDL++R+GNLKNGVADIK HK+F DW+ +Y KK +AP+ PKC+GP D S FD +EEE
Sbjct: 50 VEDFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEE 371
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 399.053 bits (1024), Expect = 3.070e-137 Identity = 200/349 (57.31%), Postives = 266/349 (76.22%), Query Frame = 3
Query: 48 LKFKNPLLNSVPSIRQIRNVFM*VSMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
LKF P + S + +N S+ +F L K E+F +W+NP + TA ++DF+RIKTLG G+FGRV+LVKHK +GNYYA+K+L K +++K KQ+E+ LNEK+IL I+FPFL+ + +SFKDNS LYMVLEF+ GGEMF+ LR + RF + +FY AQ+++AFEYLH L + YRDLKPEN+L++S GYLK+ D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKVKF S FS +LKDL++NL+QVDL++R+GNLKNGVADIK HK+F DW+ +Y KK +AP+ PKC+GP D S FD +EEE
Sbjct: 2 LKFLKPKSSDEGSSKDNKNS---ASLKEF---LDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEE 342
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 398.667 bits (1023), Expect = 3.400e-137 Identity = 194/326 (59.51%), Postives = 256/326 (78.53%), Query Frame = 3
Query: 117 VSMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
V + F L K E+F +W+NP + TA ++DF+RIKTLG G+FGRV+LVKHK +GNYYA+K+L K +++K KQ+E+ LNEK+IL I+FPFL+ + +SFKDNS LYMVLEF+ GGEMF+ LR + RF + +FY AQ+++AFEYLH L + YRDLKPEN+L++S GYLK+ D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKVKF S FS +LKDL++NL+QVDL++R+GNLKNGVADIK HK+F DW+ +Y KK +AP+ PKC+GP D S FD +EEE
Sbjct: 9 VQVKFFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEE 332
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 397.127 bits (1019), Expect = 2.527e-136 Identity = 192/317 (60.57%), Postives = 253/317 (79.81%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+F +W+NP + TA ++DF+RIKTLG G+FGRV+LVKHK +GNYYA+K+L K +++K KQ+E+ LNEK+IL I+FPFL+ + +SFKDNS LYMVLEF+ GGEMF+ LR + RF + +FY AQ+++AFEYLH L + YRDLKPEN+L++S GYLK+ D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKVKF S FS +LKDL++NL+QVDL++R+GNLKNGVADIK HK+F DW+ +Y KK +AP+ PKC+GP D S FD +EEE
Sbjct: 39 LDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEE 353
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 395.971 bits (1016), Expect = 3.103e-136 Identity = 192/317 (60.57%), Postives = 253/317 (79.81%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+F +W+NP + TA ++DF+RIKTLG G+FGRV+LVKHK +GNYYA+K+L K +++K KQ+E+ LNEK+IL I+FPFL+ + +SFKDNS LYMVLEF+ GGEMF+ LR + RF + +FY AQ+++AFEYLH L + YRDLKPEN+L++S GYLK+ D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKVKF S FS +LKDL++NL+QVDL++R+GNLKNGVADIK HK+F DW+ +Y KK +AP+ PKC+GP D S FD +EEE
Sbjct: 12 LDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEE 326
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0335495) HSP 1 Score: 385.956 bits (990), Expect = 5.620e-132 Identity = 189/318 (59.43%), Postives = 246/318 (77.36%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEET 1097
L + EEF KW P TA ++DFERIKTLG G+FGRV++V+HK +YYA+K+L K +++K KQ+E+ LNEK+IL I+FPFL+ L Y FKDNS LYMVLE+V GGEMF+ LR + RF + +FY AQ+++AFEYLHYL + YRDLKPEN+L++S GYLKV D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S F +DLKDL+RNL+QVDL++R+GNLK GV DIK K+F DW+ ++ KK +AP+ P+CKGP DTS FD +EEE
Sbjct: 22 LEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEA 337
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079852) HSP 1 Score: 385.956 bits (990), Expect = 5.620e-132 Identity = 189/318 (59.43%), Postives = 246/318 (77.36%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEET 1097
L + EEF KW P TA ++DFERIKTLG G+FGRV++V+HK +YYA+K+L K +++K KQ+E+ LNEK+IL I+FPFL+ L Y FKDNS LYMVLE+V GGEMF+ LR + RF + +FY AQ+++AFEYLHYL + YRDLKPEN+L++S GYLKV D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S F +DLKDL+RNL+QVDL++R+GNLK GV DIK K+F DW+ ++ KK +AP+ P+CKGP DTS FD +EEE
Sbjct: 22 LEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEA 337
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079851) HSP 1 Score: 385.956 bits (990), Expect = 5.620e-132 Identity = 189/318 (59.43%), Postives = 246/318 (77.36%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEET 1097
L + EEF KW P TA ++DFERIKTLG G+FGRV++V+HK +YYA+K+L K +++K KQ+E+ LNEK+IL I+FPFL+ L Y FKDNS LYMVLE+V GGEMF+ LR + RF + +FY AQ+++AFEYLHYL + YRDLKPEN+L++S GYLKV D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S F +DLKDL+RNL+QVDL++R+GNLK GV DIK K+F DW+ ++ KK +AP+ P+CKGP DTS FD +EEE
Sbjct: 22 LEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEA 337
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075529) HSP 1 Score: 297.745 bits (761), Expect = 1.468e-95 Identity = 144/296 (48.65%), Postives = 201/296 (67.91%), Query Frame = 3
Query: 207 MEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
++D++ IKT+G G FGRV L + + + Y A+K+L+ E+I+ KQIE+ NE+ IL I PF+I L +S KD+S LYM+ ++V GGE+FT LRN +F FY A+++ A EYLH L I YRDLKPEN+L+N DG+LK+ D GFAK + RTWTLCGTP+Y+APEII +KG++ AVDWWA GVL+YEM G+PPF + +E I+SGK+++ KDLI+ L+ D ++R GN+KNG D+K+H++F ++W DVY KK K P P DT FD + E+
Sbjct: 188 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKL--RDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEK 481
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075528) HSP 1 Score: 298.13 bits (762), Expect = 1.111e-94 Identity = 144/296 (48.65%), Postives = 201/296 (67.91%), Query Frame = 3
Query: 207 MEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
++D++ IKT+G G FGRV L + + + Y A+K+L+ E+I+ KQIE+ NE+ IL I PF+I L +S KD+S LYM+ ++V GGE+FT LRN +F FY A+++ A EYLH L I YRDLKPEN+L+N DG+LK+ D GFAK + RTWTLCGTP+Y+APEII +KG++ AVDWWA GVL+YEM G+PPF + +E I+SGK+++ KDLI+ L+ D ++R GN+KNG D+K+H++F ++W DVY KK K P P DT FD + E+
Sbjct: 271 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKL--RDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEK 564
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacbb (protein kinase, cAMP-dependent, catalytic, beta b [Source:ZFIN;Acc:ZDB-GENE-050904-4]) HSP 1 Score: 392.119 bits (1006), Expect = 2.451e-134 Identity = 187/317 (58.99%), Postives = 251/317 (79.18%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW++P ++T ++DF+R KTLG G+FGRV+LVKHKA+ YYA+KVL K +++K KQ+E+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNL+NGV DIK HK+F DW+ +Y++K +AP+ PKC+GP DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWESPQQSTTCLDDFDRQKTLGTGSFGRVLLVKHKASDQYYAMKVLDKQKVVKLKQVEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacaa (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [Source:ZFIN;Acc:ZDB-GENE-050114-6]) HSP 1 Score: 391.349 bits (1004), Expect = 5.319e-134 Identity = 189/324 (58.33%), Postives = 252/324 (77.78%), Query Frame = 3
Query: 123 MTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
M L K E+FL KW+NP + TA+++ FER+KTLG G+FGRV+LVKHK +G ++A+K+L K +++K KQIE+ LNEK+IL + FPFL+ L +SFKDN+ LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y KK +AP+ PKCKGP DTS FD ++EE
Sbjct: 14 MESVKEFLAKAKEDFLKKWENPAQNTASLDHFERLKTLGTGSFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEAPFIPKCKGPGDTSNFDDYDEE 335
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacab (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-040801-208]) HSP 1 Score: 389.808 bits (1000), Expect = 2.004e-133 Identity = 182/312 (58.33%), Postives = 249/312 (79.81%), Query Frame = 3
Query: 159 EEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
E+FL KW+NP + TA +EDF+R+KTLG G+FGRV+LV+H+ G +YA+K+L+K +++K KQIE+ LNEK+IL + FPFL+ L YSFKDN+ LYMV+++V GGEMF+ LR + RF + +FY +Q+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++R+GNLKNGV DIK HK+F DW+ +Y ++ +AP+ PKC+GP DTS FD +EEE
Sbjct: 25 EDFLRKWENPAQNTACLEDFDRLKTLGTGSFGRVMLVRHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNTNLYMVMQYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLMYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEAPFVPKCRGPGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351]) HSP 1 Score: 384.415 bits (986), Expect = 1.285e-130 Identity = 184/323 (56.97%), Postives = 250/323 (77.40%), Query Frame = 3
Query: 126 TDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
T L K E+FL KW+ K+TA ++DF+++KTLG G+FGRV+LVKHK + Y+A+K+L KL+++K KQIE+ LNEKKIL + FPFL+ L +FKDNS LYMV+ ++ GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV++ S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK H++F DW+ +Y+KK AP PKC+GP DTS FD+++EE
Sbjct: 58 TAMKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEE 378
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351]) HSP 1 Score: 384.415 bits (986), Expect = 1.285e-130 Identity = 184/323 (56.97%), Postives = 250/323 (77.40%), Query Frame = 3
Query: 126 TDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
T L K E+FL KW+ K+TA ++DF+++KTLG G+FGRV+LVKHK + Y+A+K+L KL+++K KQIE+ LNEKKIL + FPFL+ L +FKDNS LYMV+ ++ GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV++ S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK H++F DW+ +Y+KK AP PKC+GP DTS FD+++EE
Sbjct: 58 TAMKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEE 378
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 398.282 bits (1022), Expect = 8.043e-137 Identity = 196/325 (60.31%), Postives = 255/325 (78.46%), Query Frame = 3
Query: 120 SMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
SM +F L K E+FL KW+NP + TA +E FERIKTLG G+FGRV+LV+HK NG+++A+K+L K +++K KQIE+ LNEK+IL + FPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY +Q+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ VY KK +AP+ PKCKGP DTS FD +EEE
Sbjct: 5 SMKEF---LAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEE 324
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: prkacb (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:100038053]) HSP 1 Score: 398.667 bits (1023), Expect = 1.019e-136 Identity = 191/317 (60.25%), Postives = 250/317 (78.86%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+ PP+ TA+++DFERIKTLG G+FGRV+LVKHK YYA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++R+GNLKNGV DIK HK+F DW+ +Y +K +AP+ PKC+GP DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWETPPQNTASLDDFERIKTLGTGSFGRVMLVKHKGAEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 397.897 bits (1021), Expect = 1.756e-136 Identity = 193/317 (60.88%), Postives = 251/317 (79.18%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NP + TA +E FERIKTLG G+FGRV+LV+HK NG+++A+K+L K +++K KQIE+ LNEK+IL + FPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY +Q+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ VY KK +AP+ PKCKGP DTS FD +EEE
Sbjct: 20 LAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 397.127 bits (1019), Expect = 2.271e-136 Identity = 193/317 (60.88%), Postives = 251/317 (79.18%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NP + TA +E FERIKTLG G+FGRV+LV+HK NG+++A+K+L K +++K KQIE+ LNEK+IL + FPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY +Q+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ VY KK +AP+ PKCKGP DTS FD +EEE
Sbjct: 6 LAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEE 320
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 397.127 bits (1019), Expect = 2.478e-136 Identity = 193/317 (60.88%), Postives = 251/317 (79.18%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NP + TA +E FERIKTLG G+FGRV+LV+HK NG+++A+K+L K +++K KQIE+ LNEK+IL + FPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY +Q+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ VY KK +AP+ PKCKGP DTS FD +EEE
Sbjct: 6 LAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEE 320
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 405.986 bits (1042), Expect = 4.805e-139 Identity = 195/325 (60.00%), Postives = 253/325 (77.85%), Query Frame = 3
Query: 120 SMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
SM +F L K E+FL KW+NPP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL +EFPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 62 SMKEF---LAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 381
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 402.905 bits (1034), Expect = 1.464e-138 Identity = 192/317 (60.57%), Postives = 249/317 (78.55%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NPP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL +EFPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 402.519 bits (1033), Expect = 1.491e-138 Identity = 192/317 (60.57%), Postives = 249/317 (78.55%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NPP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL +EFPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 7 LAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 321
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 402.519 bits (1033), Expect = 1.494e-138 Identity = 192/317 (60.57%), Postives = 249/317 (78.55%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NPP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL +EFPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 8 LAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 322
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592]) HSP 1 Score: 397.127 bits (1019), Expect = 1.878e-136 Identity = 191/325 (58.77%), Postives = 251/325 (77.23%), Query Frame = 3
Query: 120 SMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
S D L K E+FL KW+ P + TA ++ F+RIKTLG G+FGRV+LVKHK +GN+YA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L +SFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y +K +AP+ PK KGP DTS FD +EEE
Sbjct: 4 SSNDVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEE 326
BLAST of cAMP dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P68182|KAPCB_RAT (cAMP-dependent protein kinase catalytic subunit beta OS=Rattus norvegicus OX=10116 GN=Prkacb PE=1 SV=2) HSP 1 Score: 402.905 bits (1034), Expect = 1.024e-137 Identity = 192/317 (60.57%), Postives = 249/317 (78.55%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NPP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL +EFPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P68181|KAPCB_MOUSE (cAMP-dependent protein kinase catalytic subunit beta OS=Mus musculus OX=10090 GN=Prkacb PE=1 SV=2) HSP 1 Score: 402.905 bits (1034), Expect = 1.024e-137 Identity = 192/317 (60.57%), Postives = 249/317 (78.55%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NPP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL +EFPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P68180|KAPCB_CRIGR (cAMP-dependent protein kinase catalytic subunit beta OS=Cricetulus griseus OX=10029 GN=PRKACB PE=2 SV=2) HSP 1 Score: 402.905 bits (1034), Expect = 1.024e-137 Identity = 192/317 (60.57%), Postives = 249/317 (78.55%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NPP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL +EFPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P36887|KAPCA_PIG (cAMP-dependent protein kinase catalytic subunit alpha OS=Sus scrofa OX=9823 GN=PRKACA PE=1 SV=4) HSP 1 Score: 397.127 bits (1019), Expect = 1.657e-135 Identity = 191/317 (60.25%), Postives = 249/317 (78.55%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NP + TA ++ FERIKTLG G+FGRV+LVKHK GN++A+K+L K +++K KQIE+ LNEK+IL + FPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y +K +AP+ PK KGP DTS FD +EEE
Sbjct: 20 LAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P22694|KAPCB_HUMAN (cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB PE=1 SV=2) HSP 1 Score: 396.356 bits (1017), Expect = 4.275e-135 Identity = 189/317 (59.62%), Postives = 247/317 (77.92%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+NP + A +EDFER KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PK +G DTS FD +EEE
Sbjct: 20 LAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A4S2L5E2 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_010367 PE=3 SV=1) HSP 1 Score: 516.153 bits (1328), Expect = 6.848e-180 Identity = 244/329 (74.16%), Postives = 289/329 (87.84%), Query Frame = 3
Query: 111 M*VSMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEET 1097
M +F+ +L +K +EF ++ NPPK +MEDFERI+TLG+GAFGRV+LV+H YYALK+LSK+EI+KS+QIENA+NEK+ILA FPF+I L +SFKDNSYLYMV+EFVIGGEMFTLLRNMRRFPDN+VKFY AQV+MAFEYLH L+IAYRDLKPEN+L+ +G+LKV D+GFAKMIPKDKRTWTLCGTPDYMAPEIIM+KGYHCAVDWWAFGVLLYEMT GFPPFMHQDQMKTFEHIISGK+KFT++F +LKDLIRNL+QVDLSRRFGNLKNG+ADIK+H YF ++DW+ +Y+ + + PYKPK KGP DTSCF+KWEEET
Sbjct: 1 MPTRQAEFDEILSEKTKEFRERYFNPPKEVVSMEDFERIRTLGRGAFGRVLLVRHWDKDQYYALKILSKIEIVKSRQIENAINEKRILAACNFPFIIKLFFSFKDNSYLYMVMEFVIGGEMFTLLRNMRRFPDNMVKFYAAQVVMAFEYLHMLTIAYRDLKPENLLITGEGFLKVADLGFAKMIPKDKRTWTLCGTPDYMAPEIIMSKGYHCAVDWWAFGVLLYEMTTGFPPFMHQDQMKTFEHIISGKIKFTNNFGPELKDLIRNLIQVDLSRRFGNLKNGIADIKEHAYFSDLDWIQLYNMQMRPPYKPKYKGPSDTSCFEKWEEET 329
BLAST of cAMP dependent protein kinase catalytic subunit vs. TrEMBL
Match: H2KU48 (Protein kinase A OS=Clonorchis sinensis OX=79923 GN=PRKACA PE=3 SV=1) HSP 1 Score: 514.227 bits (1323), Expect = 3.029e-179 Identity = 243/329 (73.86%), Postives = 289/329 (87.84%), Query Frame = 3
Query: 111 M*VSMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEET 1097
M +F+ +L +K +EF ++ NPPK +MEDFERI+TLG+GAFGRV+LV+H YYALK+LSK+EI+KS+QIENA+NEK+ILA FPF+I L +SFKDNSYLYMV+EFVIGGEMFTLLRNMRRFPDN+VKFY AQV+MAFEYLH L+IAYRDLKPEN+L+ +G+LKV D+GFAKMIPKDKRTWTLCGTPDYMAPEIIM+KGYHCAVDWWAFGVLLYEMT GFPPFMHQDQMKTFEHIISGK+KFT++F +LKDLIRNL+QVDLSRR+GNLKNG+ADIK+H YF ++DW+ +Y+ + + PYKPK KGP DTSCF+KWEEET
Sbjct: 1 MPTRQAEFDEILSEKTKEFRERYFNPPKEVVSMEDFERIRTLGRGAFGRVLLVRHWDKDQYYALKILSKIEIVKSRQIENAINEKRILAACNFPFIIKLFFSFKDNSYLYMVMEFVIGGEMFTLLRNMRRFPDNMVKFYAAQVVMAFEYLHMLTIAYRDLKPENLLITGEGFLKVADLGFAKMIPKDKRTWTLCGTPDYMAPEIIMSKGYHCAVDWWAFGVLLYEMTTGFPPFMHQDQMKTFEHIISGKIKFTNNFGPELKDLIRNLIQVDLSRRYGNLKNGIADIKEHAYFSDLDWIQLYNMQVRPPYKPKYKGPSDTSCFEKWEEET 329
BLAST of cAMP dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A074ZWV6 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_13709 PE=3 SV=1) HSP 1 Score: 513.457 bits (1321), Expect = 5.902e-179 Identity = 242/329 (73.56%), Postives = 289/329 (87.84%), Query Frame = 3
Query: 111 M*VSMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEET 1097
M +F+ +L++K +EF ++ NPPK +MEDFERI+TLG+GAFGRV+LV+H YYALK+LSK+EI+KS+QIENA+NEK+ILA FPF+I L +SFKDNSYLYMV+EFVIGGEMFTLLRNMRRFPDN+VKFY AQV+MAFEYLH L+IAYRDLKPEN+L+ +G+LKV D+GFAKMIPKDKRTWTLCGTPDYMAPEIIM+KGYHCAVDWWAFGVLLYEMT GFPPFMHQDQMKTFEHIISGK+KFT++F +LKDLIRNL+QVDLSRR+GNLKNG+ADIK+H YF ++DW+ +Y+ + + PYKPK KGP DTSCF+KWEEE
Sbjct: 1 MPTRQAEFDDILLEKTKEFRERYFNPPKEVVSMEDFERIRTLGRGAFGRVLLVRHWDKDQYYALKILSKIEIVKSRQIENAINEKRILAACNFPFIIKLFFSFKDNSYLYMVMEFVIGGEMFTLLRNMRRFPDNMVKFYAAQVVMAFEYLHMLTIAYRDLKPENLLITGEGFLKVADLGFAKMIPKDKRTWTLCGTPDYMAPEIIMSKGYHCAVDWWAFGVLLYEMTTGFPPFMHQDQMKTFEHIISGKIKFTNNFGPELKDLIRNLIQVDLSRRYGNLKNGIADIKEHAYFSDLDWLQLYNMQVRPPYKPKYKGPSDTSCFEKWEEEN 329
BLAST of cAMP dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A1S8X7H3 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=X801_01445 PE=3 SV=1) HSP 1 Score: 513.072 bits (1320), Expect = 1.144e-178 Identity = 242/329 (73.56%), Postives = 289/329 (87.84%), Query Frame = 3
Query: 111 M*VSMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEET 1097
M +F+ +L++K +EF ++ NPPK +MEDFERI+TLG+GAFGRV+LV+H YYALK+LSK+EI+KS+QIENA+NEK+ILA FPF+I L +SFKDNSYLYMV+EFVIGGEMFTLLRNMRRFPDN+VKFY AQV+MAFEYLH L+IAYRDLKPEN+L+ +G+LKV D+GFAKMIPKDKRTWTLCGTPDYMAPEIIM+KGYHCAVDWWAFGVLLYEMT GFPPFMHQDQMKTFEHIISGK+KFT++F +LKDLIRNL+QVDLSRR+GNLKNG+ADIK+H YF ++DW+ +Y+ + + PYKPK KGP DTSCF+KWEEE
Sbjct: 1 MPTRQAEFDDILLEKTKEFRERYFNPPKEVVSMEDFERIRTLGRGAFGRVLLVRHWDKDQYYALKILSKIEIVKSRQIENAINEKRILAACNFPFIIKLFFSFKDNSYLYMVMEFVIGGEMFTLLRNMRRFPDNMVKFYAAQVVMAFEYLHMLTIAYRDLKPENLLITGEGFLKVADLGFAKMIPKDKRTWTLCGTPDYMAPEIIMSKGYHCAVDWWAFGVLLYEMTTGFPPFMHQDQMKTFEHIISGKIKFTNNFGPELKDLIRNLIQVDLSRRYGNLKNGIADIKEHAYFSDLDWLQLYNMQVRPPYKPKYKGPSDTSCFEKWEEEN 329
BLAST of cAMP dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A504YU12 (cAMP-dependent protein kinase catalytic subunit alpha OS=Fasciola gigantica OX=46835 GN=FGIG_01338 PE=3 SV=1) HSP 1 Score: 511.146 bits (1315), Expect = 6.468e-178 Identity = 243/329 (73.86%), Postives = 288/329 (87.54%), Query Frame = 3
Query: 111 M*VSMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEET 1097
M +F+ +L +K +EF + NP K +MEDFERI+TLG+GAFGRV+LV+H YYA+KVLSK+EI+KS+QI+NA+NEK+ILA FPF+I LAYSFKDNSYLYMV+EFVIGGEMFTLLRNMRRFPDN+VKFY AQV+MAFEYLH L+IAYRDLKPEN+L+ +G+LKV D+GFAKMIPKDKRTWTLCGTPDYMAPEIIM+KGYHCAVDWWAFGVLLYEMT GFPPFMHQDQMKTFEHIISGK+KFT++F +LKDLIRNL+QVDLSRR+GNLKNG++DIK+H YF ++DWM +Y+ + + PYKPK KGP DTSCF+KWEEET
Sbjct: 1 MPTKQAEFDEILNEKAKEFRELYFNPTKDPVSMEDFERIRTLGRGAFGRVLLVRHWDKDAYYAMKVLSKVEIVKSRQIDNAINEKRILAACNFPFIIRLAYSFKDNSYLYMVMEFVIGGEMFTLLRNMRRFPDNMVKFYAAQVVMAFEYLHLLTIAYRDLKPENLLITGEGFLKVADLGFAKMIPKDKRTWTLCGTPDYMAPEIIMSKGYHCAVDWWAFGVLLYEMTTGFPPFMHQDQMKTFEHIISGKIKFTNNFGPELKDLIRNLIQVDLSRRYGNLKNGISDIKEHAYFADLDWMQLYNLQMRPPYKPKYKGPSDTSCFEKWEEET 329
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000050353.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308]) HSP 1 Score: 397.897 bits (1021), Expect = 9.471e-137 Identity = 190/317 (59.94%), Postives = 251/317 (79.18%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+ PP++T ++DFER+KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR + RF ++ +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y++K +AP PKC+GP DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000050990.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308]) HSP 1 Score: 398.282 bits (1022), Expect = 1.027e-136 Identity = 190/317 (59.94%), Postives = 251/317 (79.18%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+ PP++T ++DFER+KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR + RF ++ +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y++K +AP PKC+GP DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000056663.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308]) HSP 1 Score: 398.282 bits (1022), Expect = 3.812e-136 Identity = 190/317 (59.94%), Postives = 251/317 (79.18%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+ PP++T ++DFER+KTLG G+FGRV+LVKHKA YYA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR + RF ++ +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y++K +AP PKC+GP DTS FD +EEE
Sbjct: 64 LAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEE 378
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacbb (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:103034112]) HSP 1 Score: 395.586 bits (1015), Expect = 8.007e-136 Identity = 189/317 (59.62%), Postives = 251/317 (79.18%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+ PP++T T++DFER+KTLG G+FGRV+LVKHK ++A+KVL K +++K KQIE+ LNEK+IL + FPFL+ L YSFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++R+GNLKNGV DIK HK+F DW+ +Y++K +AP+ PKC+GP DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWECPPQSTTTLDDFERLKTLGTGSFGRVMLVKHKGTEQFFAMKVLDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103024963]) HSP 1 Score: 395.586 bits (1015), Expect = 9.652e-136 Identity = 190/324 (58.64%), Postives = 252/324 (77.78%), Query Frame = 3
Query: 123 MTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
M L K E+FL KW+NP + TA+++ FER+KTLG G+FGRV+LVKHK G ++A+K+L K +++K KQIE+ LNEK+IL + FPFL+ L +SFKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV+DIK HK+F DW+ +Y +K +AP+ PKCKGP DTS FD +EEE
Sbjct: 14 MESVKEFLAKAKEDFLKKWENPAQNTASLDQFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEE 335
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 328.946 bits (842), Expect = 2.731e-111 Identity = 161/270 (59.63%), Postives = 210/270 (77.78%), Query Frame = 3
Query: 285 GNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
G + +LK + +++K KQ+E+ LNEK+IL I FPFL+ L YSFKDNS LYMVLE+V GGEMF+ LR + RF + +FY AQ+++AFEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y +K +AP+ PKCKGP D S FD +EEE
Sbjct: 4 GQHVSLKATKRTKVVKLKQVEHTLNEKRILQAISFPFLVRLEYSFKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIPKCKGPGDASNFDDYEEE 271
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 243.817 bits (621), Expect = 1.381e-75 Identity = 125/300 (41.67%), Postives = 185/300 (61.67%), Query Frame = 3
Query: 189 PKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHY-LSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTW-TLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDK 1082
PK+ TM +F+ +K LGKG FG+VILV+ KA G YYA+K+L K I+ ++ + L E ++L + PFL L YSF+ + L V+E+V GGE+F L R F ++ +FYGA+++ A +YLH ++ YRDLK EN++L+ DG++K+ D G K D T T CGTP+Y+APE++ + Y AVDWW GV++YEM G PF +QD K FE I+ ++F + S D + L+ L++ D +R G + +I +H +F I W DVYD+K P+KP+ DT FD+
Sbjct: 141 PKSKVTMNNFDYLKLLGKGTFGKVILVREKATGQYYAMKILKKEVIVAKDEVAHTLTENRVLQTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPFKPQVASETDTRYFDE 440
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002200.1 (pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 gene:ENSPMAG00000001993.1 transcript:ENSPMAT00000002200.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 237.654 bits (605), Expect = 5.382e-75 Identity = 112/261 (42.91%), Postives = 169/261 (64.75%), Query Frame = 3
Query: 225 IKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISG--KVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDW 1001
I TLG G FGRV LVK K + +ALK L K +++S+Q E+ +EK+IL PF++ +F+D ++++++E +GGE++++LR+ F + +F A V+ A YLH I YRDLKPEN+LL++ GY+K+ D GFAK + ++ WT CGTP+Y+ PE+I+N+G+ D WA GVL+YE+ AG PPF D MKT+ I+ G +V F + +D+IR L + + S R GN K+GV D+++HK+F DW
Sbjct: 37 IATLGVGGFGRVQLVKLKDSDVTFALKCLKKKFVVESRQQEHVYSEKRILQECSCPFIVRFYRTFRDQKFVFLLMEACLGGELWSVLRDSGGFQEVSARFCVACVVEALAYLHARGILYRDLKPENLLLDARGYIKMADFGFAKKLACGRKAWTFCGTPEYVCPEMIVNRGHDRGADCWALGVLVYELLAGVPPFSGTDPMKTYNAILWGMERVHFPNEVGKRAEDIIRRLCRQNPSERLGNQKHGVGDVRKHKWFQGFDW 297
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004852.1 (pep scaffold:Pmarinus_7.0:GL488704:3417:7135:1 gene:ENSPMAG00000004407.1 transcript:ENSPMAT00000004852.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 209.92 bits (533), Expect = 2.612e-66 Identity = 95/164 (57.93%), Postives = 129/164 (78.66%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKV 635
L K E+FL KW+NP + T+ ++DFER+KTLG G+FGRV+LVKHKA Y+A+K+L K +++K KQ+E+ LNEK+IL I FPFL+ L YS+KDNS LYMVLE+V GGEMF+ LR + RF + +FY AQ+++AFEYLH L + YRDLKPEN+L++ GY++V
Sbjct: 20 LAKAKEDFLKKWENPQQNTSCLDDFERMKTLGTGSFGRVMLVKHKATDRYFAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVSLEYSYKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQV 183
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 208.764 bits (530), Expect = 7.172e-63 Identity = 104/272 (38.24%), Postives = 163/272 (59.93%), Query Frame = 3
Query: 201 ATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILA-CIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKM-IPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDV 1010
A DF+ + LGKG+FG+V+L KHK++G +YA+KV+ K I++ K+ ++ + E+ +L + PFL+ L YSF+ LY V+++V GGE+F L+ FP++ +FY A++ A YLH L+I YRDLKPENILL+ G++ + D G K I T T CGTP+Y+APE++ Y VDWW G +LYEM G PPF ++ + +E I+ ++ + ++ L+ D +R G + + +IK H +F I+W D+
Sbjct: 87 AKPSDFDFLTVLGKGSFGKVLLAKHKSDGIFYAVKVMKKSIILQKKEEKHIMAERNVLVKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRLGATSD-ILEIKNHVFFSTINWNDL 357
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]) HSP 1 Score: 302.368 bits (773), Expect = 9.814e-100 Identity = 145/302 (48.01%), Postives = 206/302 (68.21%), Query Frame = 3
Query: 192 KATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVY-DXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
K T+ DF+ ++TLG G+FGRV LV+ NG YYA+KVL K +++K KQ+E+ +E+++L +E PFLI + +F+D ++MV++++ GGE+F+LLR +RFP+ + KFY A+VI+A EYLH +I YRDLKPENILL+ +G++K+ D GFAK + TWTLCGTPDY+APE+I K Y+ +VDWW+ GVL+YEM AG+ PF MKT+E I+ GKV + F D+ DL+ L+ DL+RR GNL++G DIK H +F E+ W + P G DTS FD++ EE
Sbjct: 62 KGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEV--QTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEE 361
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 296.975 bits (759), Expect = 1.946e-97 Identity = 138/298 (46.31%), Postives = 210/298 (70.47%), Query Frame = 3
Query: 204 TMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDX-XXXXXXXXXXXXXDDTSCFDKWEEE 1094
++ DF+ ++TLG G+FGRV L++ NG +YALK L K I+K KQ+E+ +E+++L+ + PF+I + +F+D+ ++MV++++ GGE+F+LLR +RFP+ + KFY A+V +A EYLH I YRDLKPENILL+ +G++K+ D GFAK +P T+TLCGTPDY+APE++ K Y+ +VDWW+FGVL+YEM AG+ PF + + MKT+E+I++ ++KF F D +DL++ L+ DLS R GNL+NG D+K H +F E+ W + + P +G DTS FD++ EE
Sbjct: 84 SLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEE 379
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 296.59 bits (758), Expect = 2.341e-97 Identity = 136/298 (45.64%), Postives = 213/298 (71.48%), Query Frame = 3
Query: 204 TMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXX-XXXXXXXXDDTSCFDKWEEE 1094
+++DF+ ++TLG G+FGRV L++ + NG YYA+KVL K +++ KQ+E+ +E+ +L+ + PF+I + +F+D ++M+++++ GGE+F+LLR +RFP+ + KFY A+V +A EYLH I YRDLKPENILL+ +G++K+ D GFAK +P T+TLCGTPDY+APE++ K Y+ ++DWW+FG+L+YEM AG+ PF + MKT+E I++ +++F F+ D+KDL+ L+ DLS+R GNL+NG D+K H +F E+ W + + + P P +G DTS FDK+ EE
Sbjct: 83 SLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVP--DVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEE 378
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]) HSP 1 Score: 228.794 bits (582), Expect = 2.654e-68 Identity = 108/267 (40.45%), Postives = 167/267 (62.55%), Query Frame = 3
Query: 204 TMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKM-IPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDW 1001
+++DF+ +K +GKG+FG+V+ V+ K YALK + K I+ ++ + L E+ +LA ++ PF++ L +SF+ LY VL F+ GGE+F L+ RF + +FY A+++ A + LH L + YRDLKPENILL+ G++ + D G K+ + D +T T CGTP+Y+APE+++ GY AVDWW GVLLYEM G PP+ +D K ++ I+ + F F D KDL+ L+ D +RR G NG +I+ H +F ++ W
Sbjct: 343 SIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLG--YNGADEIRNHPFFSQLSW 607
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]) HSP 1 Score: 222.631 bits (566), Expect = 5.389e-66 Identity = 108/267 (40.45%), Postives = 166/267 (62.17%), Query Frame = 3
Query: 204 TMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDK-RTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDW 1001
+++DF+ +K +GKG+FG+V+ V+ K YALK L K I+ ++ + L E+ +LA ++ PF++ L +SF+ LY+VL F+ GGE+F L++ RF +FY A+++ A + LH L + YRDLKPENILL+ G++ + D G K+ KD +T T CGTP+Y+APEI++ +GY VDWW G+LLYEM G PP+ ++ ++ I+ + F F KDL+ L+ D SRR G NG +I+ H +F +I W
Sbjct: 340 SIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLG--VNGTDEIRNHPFFKDISW 604
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62]) HSP 1 Score: 290.812 bits (743), Expect = 1.486e-95 Identity = 146/299 (48.83%), Postives = 204/299 (68.23%), Query Frame = 3
Query: 201 ATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSF-SADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
T++DFE KTLG G FGRV+L + + G +YALK+++ E+I+ KQ+E+ NEK IL IE PF++ L ++ D ++LYM+LE+ GGE+FT LR RF + F+G++++ A +YLH SI YRDLKPENILL+ DG++K+ D GFAK + +TWTLCGTP+Y+APEII +KG++ AVDWWA G+L+YEM G+PPF + +E I+SGKV++ + KDLI+ L+ D +RR G++KNG D+K HK+F IDW V +K K P PK P DT FD + EE
Sbjct: 13 TTLQDFELSKTLGTGTFGRVLLARDRRGGEFYALKIMNISEVIRLKQVEHVQNEKNILMSIEHPFIVNLLWTQHDQTFLYMLLEYACGGELFTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAKEV--HDKTWTLCGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSGKVEWPKHMDNTSAKDLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFKVIDWNLVLQRKLKPPINPKISHPGDTRNFDDYPEE 309
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCZ7]) HSP 1 Score: 250.751 bits (639), Expect = 3.599e-76 Identity = 121/271 (44.65%), Postives = 174/271 (64.21%), Query Frame = 3
Query: 195 ATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISG--KVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDW 1001
A +ED +KTLG G FGRV LV+ + +ALK L K I++++Q ++ ++EKKI+ PF++ L +FKD YLYM+LE +GGE++T+LR+ F D+ +FY VI AF+YLH I YRDLKPEN+LL+ GY K+VD GFAK I ++TWT CGTP+Y+APEII+NKG+ + D+W+ G+L+YE+ G PPF D MKT+ I+ G + F + + LI+ L + + R G K G+ DI +HK+F +W
Sbjct: 345 ANVRLEDLTVVKTLGIGGFGRVELVQVAGDKRTFALKTLKKHHIVETRQQDHIMSEKKIMMESNSPFIVRLHKTFKDKKYLYMLLEVCLGGELWTILRDRGSFDDSTTRFYVGCVIEAFQYLHSKGIVYRDLKPENLLLDGHGYCKLVDFGFAKKIGFGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFSGTDPMKTYNIILKGIDMIDFPRKITRNAHALIKKLCRDNPVERLGYQKGGLKDIMKHKWFDGFNW 615
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38399 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCY8]) HSP 1 Score: 246.514 bits (628), Expect = 9.402e-75 Identity = 121/267 (45.32%), Postives = 173/267 (64.79%), Query Frame = 3
Query: 195 ATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISG--KVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFI 989
A T+ED E + TLG G FGRV LV YALK L K I+ ++Q E+ +EK+IL PF+ + +FKD Y+YM+LE +GGE++T+LR+ F D +F A V+ FEYLH I YRDLKPEN+LL++ GY+K+VD GFAK I ++TWT CGTP+Y+APEII+NKG+ + D+W+ G+L++E+ G PPF D MKT+ I+ G V+F + ++LI+ L + + R G K+G++DIK+HKY +
Sbjct: 324 ADLTLEDLEVVATLGTGGFGRVELVT-------YALKCLKKKHILDTRQQEHVYSEKRILMETNSPFICKIYRTFKDRKYVYMLLEACLGGELWTILRDRGTFEDATARFCIACVVEGFEYLHSKGIVYRDLKPENLLLDAKGYVKLVDFGFAKKIGSGRKTWTFCGTPEYVAPEIILNKGHDLSSDYWSLGILIFELLTGSPPFSSSDPMKTYNIILRGLDMVEFPKRIGRNPQNLIKRLCKDNPVERLGYQKDGLSDIKKHKYVV 583
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2]) HSP 1 Score: 224.172 bits (570), Expect = 1.131e-68 Identity = 110/278 (39.57%), Postives = 171/278 (61.51%), Query Frame = 3
Query: 183 NPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILA-CIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKM-IPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDV 1010
N PKA + DF +K +GKG+FG+V L K+K +YA+KVL+K I K + ++ + E+ +L + PFL+ L YSF+ LY VL++V GGE+F L+ R FP++ +FY A++ A YLH L I YRDLKPENILL+S G++ + D G K I + T T CGTP+Y+APE++ + Y +VDWW G +LYEM G PPF +D + +++I+ ++ ++ S + ++ L+Q D ++R G+ + DI+ H +F I+W +
Sbjct: 65 NNPKAKPS--DFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTHPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQL 340
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521]) HSP 1 Score: 219.55 bits (558), Expect = 8.674e-67 Identity = 123/305 (40.33%), Postives = 180/305 (59.02%), Query Frame = 3
Query: 183 NPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNY----YALKVLSKLEIIKS-KQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAK-MIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFD 1079
NP E FE +K LGKG +G+V LVK K +G+ +A+KVL K II+S K + E+ IL C++ PF++ L Y+F+ LY++LE++ GGE+F L F ++ FY +++ MA E+LH I YRDLKPENILL+++G++K+ D G K I ++ T T CGT +YMAPEI+ G+ AVDWW+ G L+Y+M G PPF ++ KT + I+ GK+ + + KD IR L++ R G + IK H +F I W D+ KK + P++P G +D S FD
Sbjct: 54 NPKDEKVGPESFELLKVLGKGGYGKVFLVK-KNHGHSKEKIFAMKVLKKAAIIRSQKDTAHTKAERNILECVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFLEDTACFYLSEISMALEHLHKQGIVYRDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKGKLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPFRPSISGEEDVSQFD 357
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000007944.2 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:101160305]) HSP 1 Score: 395.586 bits (1015), Expect = 7.454e-136 Identity = 189/317 (59.62%), Postives = 250/317 (78.86%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+ PP+ T +++DFER KTLG G+FGRV+LVKHKA +YA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR RF ++ +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y++K +AP+ PKC+GP DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWECPPQCTTSLDDFERFKTLGTGSFGRVMLVKHKATNQFYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLVYAFKDNSNLYMVMEYVPGGEMFSHLRRTGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKKV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYERKIEAPFLPKCRGPGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000028912.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:101160305]) HSP 1 Score: 395.586 bits (1015), Expect = 2.695e-135 Identity = 189/317 (59.62%), Postives = 250/317 (78.86%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+ PP+ T +++DFER KTLG G+FGRV+LVKHKA +YA+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR RF ++ +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNLKNGV DIK HK+F DW+ +Y++K +AP+ PKC+GP DTS FD +EEE
Sbjct: 49 LAKAKEDFLRKWECPPQCTTSLDDFERFKTLGTGSFGRVMLVKHKATNQFYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLVYAFKDNSNLYMVMEYVPGGEMFSHLRRTGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKKV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYERKIEAPFLPKCRGPGDTSNFDDYEEE 363
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000033457.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876]) HSP 1 Score: 393.66 bits (1010), Expect = 4.350e-135 Identity = 188/317 (59.31%), Postives = 252/317 (79.50%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+ PP++T +EDF+RIKTLG G+FGRV+LVKHK++ Y+A+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++R+GNLKNGV DIK HK+F DW+ +Y++K +AP+ PKC+GP DTS FD +EEE
Sbjct: 20 LAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEE 334
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000035979.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876]) HSP 1 Score: 393.275 bits (1009), Expect = 6.471e-135 Identity = 188/317 (59.31%), Postives = 252/317 (79.50%), Query Frame = 3
Query: 144 LIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
L K E+FL KW+ PP++T +EDF+RIKTLG G+FGRV+LVKHK++ Y+A+K+L K +++K KQIE+ LNEK+IL + FPFL+ L Y+FKDNS LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++R+GNLKNGV DIK HK+F DW+ +Y++K +AP+ PKC+GP DTS FD +EEE
Sbjct: 23 LAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEE 337
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101163742]) HSP 1 Score: 393.66 bits (1010), Expect = 1.330e-134 Identity = 189/328 (57.62%), Postives = 252/328 (76.83%), Query Frame = 3
Query: 111 M*VSMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
M + + D L K E+FL KW+NP + TA ++ FER+KTLG G+FGRV+LVKHK G ++A+K+L K +++K KQIE+ LNEK+IL + FPFL+ L +SFKD S LYMV+E+V GGEMF+ LR + RF + +FY AQ+++ FEYLH L + YRDLKPEN+L++ GY++V D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FS+DLKDL+RNL+QVDL++RFGNL+NGV DIK HK+F DW+ +Y +K +AP+ PKCKGP DTS FD +EEE
Sbjct: 35 MPIVLPDVKEFLAKAKEDFLKKWENPAQQTAALDHFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEHSFKDTSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEE 360
BLAST of cAMP dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000077092.1 (SMESG000077092.1) HSP 1 Score: 642.499 bits (1656), Expect = 0.000e+0 Identity = 325/325 (100.00%), Postives = 325/325 (100.00%), Query Frame = 3
Query: 123 MTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEET 1097
MTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDKKPKAPYKPKCKGPDDTSCFDKWEEET
Sbjct: 1 MTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDKKPKAPYKPKCKGPDDTSCFDKWEEET 325
BLAST of cAMP dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000037955.1 (SMESG000037955.1) HSP 1 Score: 398.282 bits (1022), Expect = 4.731e-137 Identity = 180/289 (62.28%), Postives = 231/289 (79.93%), Query Frame = 3
Query: 138 AVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWM 1004
A+L KK ++F KW +PP + + + IK LGKGAFG+VILVKH +G YA K LSK ++IK++Q+ENA+NEK I+AC FPF+I + +F+DN+ LY++LEF GGE+F LLR ++RFP+ VKFY QV+M EYLH L+IAYRDLKPEN+L+ DGYLKV D+GFAK+IP++KRT+TLCGTPDYMAPEII NKGY VDWWAFGVL+YE+ +G PPFM +DQMKTFE IISGK KFT +F ++KDL+ NL+QVDLS+RFGNL+NGV DI+ H++F EIDW+
Sbjct: 10 AMLEKKKKDFDAKWKSPPTFNSEISHYLPIKALGKGAFGKVILVKHIDSGRLYACKQLSKAQVIKTRQVENAMNEKNIIACCNFPFVIGIGSTFQDNTNLYLLLEFASGGELFGLLRKLKRFPEGWVKFYTCQVLMGLEYLHCLTIAYRDLKPENVLICEDGYLKVADLGFAKLIPREKRTYTLCGTPDYMAPEIIQNKGYSFPVDWWAFGVLIYELISGVPPFMQRDQMKTFERIISGKFKFTENFRPEVKDLVTNLLQVDLSKRFGNLQNGVCDIRNHEFFHEIDWV 298
BLAST of cAMP dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 385.185 bits (988), Expect = 1.494e-129 Identity = 192/350 (54.86%), Postives = 257/350 (73.43%), Query Frame = 3
Query: 45 SLKFKNPLLNSVPSIRQIRNVFM*VSMTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
++ NP+ V S I+N+ + + A L + F+ KWD P + TA + DFER++TLG G+FGRV+LV+HK Y A+K+L K +++K KQ+E+ LNEK+IL I F FL+ L Y FKDNS LYMVLEFV GGEMF+ LR + RF + +FY AQ+++AFEYLHYL + YRDLKPEN+L++S GY+KV D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FSADLKDL+RNL+QVDL++R+GNLKN V DIK HK+F+ DW+ ++ K+ +AP+ P KGP D+S FD +EEE
Sbjct: 144 NINIDNPMYLPV-STSCIKNIEINIRDDSVKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEE 490
BLAST of cAMP dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 381.719 bits (979), Expect = 2.836e-127 Identity = 184/310 (59.35%), Postives = 241/310 (77.74%), Query Frame = 3
Query: 165 FLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
F+ KWD P + TA + DFER++TLG G+FGRV+LV+HK Y A+K+L K +++K KQ+E+ LNEK+IL I F FL+ L Y FKDNS LYMVLEFV GGEMF+ LR + RF + +FY AQ+++AFEYLHYL + YRDLKPEN+L++S GY+KV D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FSADLKDL+RNL+QVDL++R+GNLKN V DIK HK+F+ DW+ ++ K+ +AP+ P KGP D+S FD +EEE
Sbjct: 258 FVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEE 565
BLAST of cAMP dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 380.948 bits (977), Expect = 2.646e-126 Identity = 184/310 (59.35%), Postives = 241/310 (77.74%), Query Frame = 3
Query: 165 FLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKHKANGNYYALKVLSKLEIIKSKQIENALNEKKILACIEFPFLIYLAYSFKDNSYLYMVLEFVIGGEMFTLLRNMRRFPDNLVKFYGAQVIMAFEYLHYLSIAYRDLKPENILLNSDGYLKVVDMGFAKMIPKDKRTWTLCGTPDYMAPEIIMNKGYHCAVDWWAFGVLLYEMTAGFPPFMHQDQMKTFEHIISGKVKFTSSFSADLKDLIRNLVQVDLSRRFGNLKNGVADIKQHKYFIEIDWMDVYDXXXXXXXXXXXXXXDDTSCFDKWEEE 1094
F+ KWD P + TA + DFER++TLG G+FGRV+LV+HK Y A+K+L K +++K KQ+E+ LNEK+IL I F FL+ L Y FKDNS LYMVLEFV GGEMF+ LR + RF + +FY AQ+++AFEYLHYL + YRDLKPEN+L++S GY+KV D GFAK + RTWTLCGTP+Y+APEII++KGY+ AVDWWA GVL+YEM AG+PPF ++ +E I+SGKV+F S FSADLKDL+RNL+QVDL++R+GNLKN V DIK HK+F+ DW+ ++ K+ +AP+ P KGP D+S FD +EEE
Sbjct: 306 FVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEE 613 The following BLAST results are available for this feature:
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of cAMP dependent protein kinase catalytic subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30026769 ID=SMED30026769|Name=cAMP dependent protein kinase catalytic subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1393bpback to top protein sequence of SMED30026769-orf-1 >SMED30026769-orf-1 ID=SMED30026769-orf-1|Name=SMED30026769-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=342bp MTDFNAVLIKKHEEFLVKWDNPPKATATMEDFERIKTLGKGAFGRVILVKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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