S-methyl-5'-thioadenosine phosphorylase

Overview
NameS-methyl-5'-thioadenosine phosphorylase
Smed IDSMED30026736
Length (bp)1247
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of S-methyl-5'-thioadenosine phosphorylase (SMED30026736) t-SNE clustered cells

Violin plots show distribution of expression levels for S-methyl-5'-thioadenosine phosphorylase (SMED30026736) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of S-methyl-5'-thioadenosine phosphorylase (SMED30026736) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for S-methyl-5'-thioadenosine phosphorylase (SMED30026736) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30026736

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 16

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pigment cellSMED30026736 SmedASXL_002463SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult RNA-sequencing evidence
gutSMED30026736 dd_Smed_v4_2328_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30026736 dd_Smed_v4_2328_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30026736 dd_Smed_v4_2328_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30026736 dd_Smed_v4_2328_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026736 Contig24141uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026736 Contig24141newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026736 Contig34116newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026736 Contig34116uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026736 Contig52751uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026736 Contig52751newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pigment cellSMED30026736 dd_Smed_v6_2328_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30026736 dd_Smed_v6_2328_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
glial cellSMED30026736 dd_Smed_v6_2328_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30026736 Contig24141uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30026736 Contig24141newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Human
Match: MTAP (methylthioadenosine phosphorylase [Source:HGNC Symbol;Acc:HGNC:7413])

HSP 1 Score: 290.041 bits (741), Expect = 6.910e-96
Identity = 138/271 (50.92%), Postives = 189/271 (69.74%), Query Frame = 3 
Query:  105 AIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIEQFTV 917
            A+K+GIIGGTGL+   I +      V TPFG PSD+L  G I +  C+L+ RHG+ HTI P+ +NY+AN+WALK   CTHVI  T CG L+   +PGD +I+DQF DRT  R Q+FYDG  +   GV HIPM+EPFC +TR++LI+ A ++G + H  GT+VTIEGPRFSS+ ES  +   GA VINMTTVPEV+LAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  ++++ +I  I   +W ETL+ N + + QF+V
Sbjct:    9 AVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLH-NLKNMAQFSV 278
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Human
Match: MTAP (methylthioadenosine phosphorylase [Source:HGNC Symbol;Acc:HGNC:7413])

HSP 1 Score: 286.189 bits (731), Expect = 4.435e-94
Identity = 136/269 (50.56%), Postives = 187/269 (69.52%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIEQFTV 917
            ++GIIGGTGL+   I +      V TPFG PSD+L  G I +  C+L+ RHG+ HTI P+ +NY+AN+WALK   CTHVI  T CG L+   +PGD +I+DQF DRT  R Q+FYDG  +   GV HIPM+EPFC +TR++LI+ A ++G + H  GT+VTIEGPRFSS+ ES  +   GA VINMTTVPEV+LAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  ++++ +I  I   +W ETL+ N + + QF+V
Sbjct:   28 RIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLH-NLKNMAQFSV 295
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Human
Match: MTAP (methylthioadenosine phosphorylase [Source:HGNC Symbol;Acc:HGNC:7413])

HSP 1 Score: 286.189 bits (731), Expect = 1.421e-93
Identity = 134/260 (51.54%), Postives = 182/260 (70.00%), Query Frame = 3 
Query:  105 AIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLN 884
            A+K+GIIGGTGL+   I +      V TPFG PSD+L  G I +  C+L+ RHG+ HTI P+ +NY+AN+WALK   CTHVI  T CG L+   +PGD +I+DQF DRT  R Q+FYDG  +   GV HIPM+EPFC +TR++LI+ A ++G + H  GT+VTIEGPRFSS+ ES  +   GA VINMTTVPEV+LAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  ++++ +I  I   +W ETL+
Sbjct:    9 AVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLH 268
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Human
Match: MTAP (methylthioadenosine phosphorylase [Source:HGNC Symbol;Acc:HGNC:7413])

HSP 1 Score: 275.404 bits (703), Expect = 1.165e-90
Identity = 123/224 (54.91%), Postives = 162/224 (72.32%), Query Frame = 3 
Query:  105 AIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVH 776
            A+K+GIIGGTGL+   I +      V TPFG PSD+L  G I +  C+L+ RHG+ HTI P+ +NY+AN+WALK   CTHVI  T CG L+   +PGD +I+DQF DRT  R Q+FYDG  +   GV HIPM+EPFC +TR++LI+ A ++G + H  GT+VTIEGPRFSS+ ES  +   GA VINMTTVPEV+LAKE G+CYAS+A+ TDYD W ++E++ +
Sbjct:    9 AVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEACY 232
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Human
Match: AL359922.1 (novel transcript)

HSP 1 Score: 129.413 bits (324), Expect = 1.209e-35
Identity = 58/109 (53.21%), Postives = 75/109 (68.81%), Query Frame = 3 
Query:  105 AIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRT 431
            A+K+GIIGGTGL+   I +      V TPFG PSD+L  G I +  C+L+ RHG+ HTI P+ +NY+AN+WALK   CTHVI  T CG L+   +PGD +I+DQF DRT
Sbjct:    9 AVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRT 117
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Celegans
Match: B0228.7 (S-methyl-5'-thioadenosine phosphorylase [Source:UniProtKB/Swiss-Prot;Acc:Q09438])

HSP 1 Score: 217.238 bits (552), Expect = 7.730e-68
Identity = 118/271 (43.54%), Postives = 156/271 (57.56%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDW-IETLNRNNELIEQFTV 917
            +KVGIIGG+GL    I    +   V TP+G PSD + +G I+   C+L+ RHG+ H I P N+N+RANLWAL S     +IA T CG LQ + +PG  +  D  FDRT  R  TF+DG  +   GV HI     + E+ RQ+LI  A +     H++G  V IEGPRFS+K ES  +   GAS++NMT +PE ILAKELG+ YA+ A+VTDYD W   ED V    V  V   N E+   + +E++  I   DW  E L    E  E   +
Sbjct:    2 VKVGIIGGSGLEDPNILLDPVTVAVDTPYGKPSDDVVEGTINGVECVLLARHGRKHDIMPGNVNFRANLWALYSRGVDVIIASTACGSLQENVEPGHLLFPDSVFDRTTGRQSTFFDGSYDQAPGVCHIQAHPTYNEKLRQVLISTAERCQLVHHRTGFGVCIEGPRFSTKAESMVFKSWGASLVNMTMMPECILAKELGIPYATTALVTDYDCW-KEEDHVTASSVMKVFAANVEKAKTLFVEAVGEIGKIDWSAEILKLKTEARESVMI 271
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Celegans
Match: B0228.7 (S-methyl-5'-thioadenosine phosphorylase [Source:UniProtKB/Swiss-Prot;Acc:Q09438])

HSP 1 Score: 217.238 bits (552), Expect = 7.730e-68
Identity = 118/271 (43.54%), Postives = 156/271 (57.56%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDW-IETLNRNNELIEQFTV 917
            +KVGIIGG+GL    I    +   V TP+G PSD + +G I+   C+L+ RHG+ H I P N+N+RANLWAL S     +IA T CG LQ + +PG  +  D  FDRT  R  TF+DG  +   GV HI     + E+ RQ+LI  A +     H++G  V IEGPRFS+K ES  +   GAS++NMT +PE ILAKELG+ YA+ A+VTDYD W   ED V    V  V   N E+   + +E++  I   DW  E L    E  E   +
Sbjct:    2 VKVGIIGGSGLEDPNILLDPVTVAVDTPYGKPSDDVVEGTINGVECVLLARHGRKHDIMPGNVNFRANLWALYSRGVDVIIASTACGSLQENVEPGHLLFPDSVFDRTTGRQSTFFDGSYDQAPGVCHIQAHPTYNEKLRQVLISTAERCQLVHHRTGFGVCIEGPRFSTKAESMVFKSWGASLVNMTMMPECILAKELGIPYATTALVTDYDCW-KEEDHVTASSVMKVFAANVEKAKTLFVEAVGEIGKIDWSAEILKLKTEARESVMI 271
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Celegans
Match: B0228.7 (S-methyl-5'-thioadenosine phosphorylase [Source:UniProtKB/Swiss-Prot;Acc:Q09438])

HSP 1 Score: 217.238 bits (552), Expect = 7.730e-68
Identity = 118/271 (43.54%), Postives = 156/271 (57.56%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDW-IETLNRNNELIEQFTV 917
            +KVGIIGG+GL    I    +   V TP+G PSD + +G I+   C+L+ RHG+ H I P N+N+RANLWAL S     +IA T CG LQ + +PG  +  D  FDRT  R  TF+DG  +   GV HI     + E+ RQ+LI  A +     H++G  V IEGPRFS+K ES  +   GAS++NMT +PE ILAKELG+ YA+ A+VTDYD W   ED V    V  V   N E+   + +E++  I   DW  E L    E  E   +
Sbjct:    2 VKVGIIGGSGLEDPNILLDPVTVAVDTPYGKPSDDVVEGTINGVECVLLARHGRKHDIMPGNVNFRANLWALYSRGVDVIIASTACGSLQENVEPGHLLFPDSVFDRTTGRQSTFFDGSYDQAPGVCHIQAHPTYNEKLRQVLISTAERCQLVHHRTGFGVCIEGPRFSTKAESMVFKSWGASLVNMTMMPECILAKELGIPYATTALVTDYDCW-KEEDHVTASSVMKVFAANVEKAKTLFVEAVGEIGKIDWSAEILKLKTEARESVMI 271
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Fly
Match: Mtap (gene:FBgn0034215 transcript:FBtr0086916)

HSP 1 Score: 263.848 bits (673), Expect = 8.365e-86
Identity = 126/258 (48.84%), Postives = 171/258 (66.28%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETL 881
            +K+GIIGG+GL+   I ++     V TP+G+PSD+L +G I+   C+L+ RHG+ H I P+N+NYRAN+WAL+ + CTH+I  T CG L+   KPG+ ++   F DRT KR+QTFYDG+  SP GV H+PM   F ERTR IL++AA ++    H   T+VTIEGPRFSS+ ES  + Q G  +INMTT PEV+LAKE GL Y S+AI TDYD W    + V+VQ V      N  +V  I++ ++  I  EDW E +
Sbjct:   16 VKIGIIGGSGLDDPDILEQRQERVVETPYGEPSDALIEGEINGVQCVLLARHGRKHDIMPSNVNYRANIWALRDVGCTHLIVSTACGSLREEIKPGNLVVPHDFIDRTTKRLQTFYDGKAQSPRGVCHLPMFPAFSERTRNILLQAAKELEIPAHDKATIVTIEGPRFSSRSESHMFRQWGGDLINMTTCPEVVLAKEAGLLYGSVAIATDYDCWRMGCEGVNVQDVLRTFAENVIKVKKILVNAVGRIAKEDWSEDI 273
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Fly
Match: Mtap (gene:FBgn0034215 transcript:FBtr0345803)

HSP 1 Score: 263.848 bits (673), Expect = 8.365e-86
Identity = 126/258 (48.84%), Postives = 171/258 (66.28%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETL 881
            +K+GIIGG+GL+   I ++     V TP+G+PSD+L +G I+   C+L+ RHG+ H I P+N+NYRAN+WAL+ + CTH+I  T CG L+   KPG+ ++   F DRT KR+QTFYDG+  SP GV H+PM   F ERTR IL++AA ++    H   T+VTIEGPRFSS+ ES  + Q G  +INMTT PEV+LAKE GL Y S+AI TDYD W    + V+VQ V      N  +V  I++ ++  I  EDW E +
Sbjct:   16 VKIGIIGGSGLDDPDILEQRQERVVETPYGEPSDALIEGEINGVQCVLLARHGRKHDIMPSNVNYRANIWALRDVGCTHLIVSTACGSLREEIKPGNLVVPHDFIDRTTKRLQTFYDGKAQSPRGVCHLPMFPAFSERTRNILLQAAKELEIPAHDKATIVTIEGPRFSSRSESHMFRQWGGDLINMTTCPEVVLAKEAGLLYGSVAIATDYDCWRMGCEGVNVQDVLRTFAENVIKVKKILVNAVGRIAKEDWSEDI 273
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Fly
Match: Mtap (gene:FBgn0034215 transcript:FBtr0329993)

HSP 1 Score: 263.848 bits (673), Expect = 7.344e-85
Identity = 126/258 (48.84%), Postives = 171/258 (66.28%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETL 881
            +K+GIIGG+GL+   I ++     V TP+G+PSD+L +G I+   C+L+ RHG+ H I P+N+NYRAN+WAL+ + CTH+I  T CG L+   KPG+ ++   F DRT KR+QTFYDG+  SP GV H+PM   F ERTR IL++AA ++    H   T+VTIEGPRFSS+ ES  + Q G  +INMTT PEV+LAKE GL Y S+AI TDYD W    + V+VQ V      N  +V  I++ ++  I  EDW E +
Sbjct:   16 VKIGIIGGSGLDDPDILEQRQERVVETPYGEPSDALIEGEINGVQCVLLARHGRKHDIMPSNVNYRANIWALRDVGCTHLIVSTACGSLREEIKPGNLVVPHDFIDRTTKRLQTFYDGKAQSPRGVCHLPMFPAFSERTRNILLQAAKELEIPAHDKATIVTIEGPRFSSRSESHMFRQWGGDLINMTTCPEVVLAKEAGLLYGSVAIATDYDCWRMGCEGVNVQDVLRTFAENVIKVKKILVNAVGRIAKEDWSEDI 273
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Fly
Match: CG31115 (gene:FBgn0051115 transcript:FBtr0290053)

HSP 1 Score: 219.164 bits (557), Expect = 2.317e-68
Identity = 107/265 (40.38%), Postives = 165/265 (62.26%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELI 902
            IK+GIIG   L+K     + +   V TPFG PSD +  G I      L++R+G+NH I P+NINYRAN+WA++ + CTH++   T   L+   +PG  ++ +   D T++R QTFYDG   SP GV H+PM+  FCERTRQ L+ AA ++G     SGTV+T+EGPR+S+  E+  + + GA +++MT  PE ILAKE G+ YASL +VT+ + W   + +    ++ ++ K  +E +  ++I +I+ +  EDW E + +   L+
Sbjct:   18 IKIGIIGEANLDKPIYLAERMEYAVCTPFGKPSDVIIDGQIEGVNVCLLSRNGRNHDIMPSNINYRANVWAMRKMGCTHILVTNTFSSLRDTFQPGHLVVPNDVIDYTSRRAQTFYDGAVGSPLGVCHVPMNPTFCERTRQHLLSAAEELGFPTGSSGTVLTLEGPRYSTVAENNMFRKWGADLLSMTLCPEAILAKEAGIPYASLGLVTNMECWCAKQPNATTHEIIYIFKKQSENLQKVLITAIRNMAAEDWAEDILKAKILV 282
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Zebrafish
Match: mtap (methylthioadenosine phosphorylase [Source:NCBI gene;Acc:393526])

HSP 1 Score: 300.442 bits (768), Expect = 3.577e-100
Identity = 140/264 (53.03%), Postives = 187/264 (70.83%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNEL 899
            +K+GIIGG+GL+   I +      V TP+G PSD+L  G I +  C+L+ RHG+ HTI PTN+NY+AN+WALK   CTH++  T CG L+   +PGD +++DQF DRT KR+QTFYDGQP SP GV HIPM+EPFC +TR++L++ A  +G K H  GT+VTIEGPRFSS+ ES  + Q GA VINMTTVPEV+LAKE GLCYAS+A+ TDYD W ++E++V V  V   MK N  +  +I++ +I  I   DW  T+N +  +
Sbjct:    7 VKIGIIGGSGLDDPDILEGRTERYVVTPYGKPSDALILGKIKNVDCVLLARHGRQHTIMPTNVNYQANIWALKEEGCTHLLVTTACGSLREDIQPGDIVLIDQFIDRTTKRVQTFYDGQPTSPPGVCHIPMAEPFCSKTREVLLEVAQGLGVKCHTRGTMVTIEGPRFSSRAESLMFRQWGADVINMTTVPEVVLAKEAGLCYASIAMATDYDCWKEHEEAVCVDNVLKTMKENANKASSILLTAIPQICQMDWDSTINAHKSM 270
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Zebrafish
Match: pnp6 (purine nucleoside phosphorylase 6 [Source:ZFIN;Acc:ZDB-GENE-040426-1800])

HSP 1 Score: 65.0846 bits (157), Expect = 2.382e-11
Identity = 64/254 (25.20%), Postives = 111/254 (43.70%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLGIF---QKVLNSDVSTPFGDPSDSLQQ-------GLIHDKPCILINRHGKNH---TINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLA-----IVTDYDSWLDNEDSVHVQKVSHVMKLNTE 815
            KV II G+GL  L      ++V + D    F  P  ++Q        G ++ K C+ +   G+ H     N   + Y   ++ L  ++   +I     GGL    K GD +++    +      Q    G      GV    MS+ +     Q++ K A ++G +   + G    + GP + +  E +    +GA  + M+TVPEV++A+  G+    L+     +VTDYDS    E + H ++V    ++ TE
Sbjct:   30 KVAIICGSGLGGLADLLDNKQVFSYDKIPRF--PHSTVQGHKGQLVFGELNGKQCVCM--QGRFHFYEGYNVATVTYPVRVFFLLGIE--TLIVTNAAGGLNPKFKVGDIMVIKDHINMPGFAGQNPLCGHNEERFGVRFPCMSDAYDRDLAQLVRKTAKELGCDSFLQEGVYCMLAGPSYETIAECRVLQMLGADAVGMSTVPEVVIARHCGIRVFGLSLITNKVVTDYDS---KERANH-EEVLETTRMRTE 273
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Zebrafish
Match: pnp6 (purine nucleoside phosphorylase 6 [Source:ZFIN;Acc:ZDB-GENE-040426-1800])

HSP 1 Score: 65.0846 bits (157), Expect = 2.382e-11
Identity = 64/254 (25.20%), Postives = 111/254 (43.70%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLGIF---QKVLNSDVSTPFGDPSDSLQQ-------GLIHDKPCILINRHGKNH---TINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLA-----IVTDYDSWLDNEDSVHVQKVSHVMKLNTE 815
            KV II G+GL  L      ++V + D    F  P  ++Q        G ++ K C+ +   G+ H     N   + Y   ++ L  ++   +I     GGL    K GD +++    +      Q    G      GV    MS+ +     Q++ K A ++G +   + G    + GP + +  E +    +GA  + M+TVPEV++A+  G+    L+     +VTDYDS    E + H ++V    ++ TE
Sbjct:   30 KVAIICGSGLGGLADLLDNKQVFSYDKIPRF--PHSTVQGHKGQLVFGELNGKQCVCM--QGRFHFYEGYNVATVTYPVRVFFLLGIE--TLIVTNAAGGLNPKFKVGDIMVIKDHINMPGFAGQNPLCGHNEERFGVRFPCMSDAYDRDLAQLVRKTAKELGCDSFLQEGVYCMLAGPSYETIAECRVLQMLGADAVGMSTVPEVVIARHCGIRVFGLSLITNKVVTDYDS---KERANH-EEVLETTRMRTE 273
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Zebrafish
Match: pnp5a (purine nucleoside phosphorylase 5a [Source:ZFIN;Acc:ZDB-GENE-040426-2553])

HSP 1 Score: 63.929 bits (154), Expect = 5.654e-11
Identity = 61/252 (24.21%), Postives = 107/252 (42.46%), Query Frame = 3 
Query:  114 VGIIGGTGLNKLGI---------FQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNIN-YRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVT-----DYDSWLDNEDSVHVQKVSHVMKLNTERV 821
            VGI+ G+GL  L           ++ + N   ST  G  +  L  G +  +PC+ +   G+ H      I      +   K L    VI     GGL    K GD +I+    +           G  +   GV    MS+ +    +Q+ +   +++G     + G    + GP F +  E +  +++GA  + M+TV EVI+A+  G+   +L+++T     DYDS    E+  + ++V    K   E++
Sbjct:   31 VGIVCGSGLGGLADALKDQVAFNYRDIPNFPQSTVHGH-AGRLVFGTLKGRPCVCM--QGRFHLYEGYPIQKITMPMRIFKMLGVETVILTNAAGGLNQDYKVGDIMIIKDHLNMPGFAGNNPLAGHNDERFGVRFPCMSDAYDRELQQMALDVGSELGFSDFLREGVYCVLGGPSFETIAECRMLHKLGADAVGMSTVHEVIVARHCGMRVFALSLITNKAVMDYDS----EEKANHEEVLQTGKQRAEQL 275
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Zebrafish
Match: pnp4b (purine nucleoside phosphorylase 4b [Source:ZFIN;Acc:ZDB-GENE-040426-1887])

HSP 1 Score: 63.5438 bits (153), Expect = 9.169e-11
Identity = 59/250 (23.60%), Postives = 113/250 (45.20%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLG---------IFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTI---NPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEK--VHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSW-LDNEDSVHVQKVSHVMKLNTE 815
            K+ ++ G+GL  L           ++ + N  VST  G     L  G I  K C+ +   G+ H     +   + +   ++ L  ++   +I     GGL    K GD +++    +      Q    G  +   G+    MS+ + +  R++++   A++G    VH+ G    + GP F +  E++  + +G+  + M+TVPEV +AK  GL    L+++T+  S     E+ V+ ++V  + K+  E
Sbjct:   31 KIAVVCGSGLGLLADNVPNKQSFRYEDIPNFPVSTVPGHEG-CLVFGQIKGKSCVFM--QGRFHLYEGYSLCKVTFPVRIFKLMGVE--TIIVTNASGGLCQDFKVGDIMVIKDHINLPGFAGQHPLCGPNDERFGIRFPCMSDAYSKDLRKLVMDITAELGYSNFVHE-GVYCMVSGPNFETIAEARMLHILGSDSVGMSTVPEVTVAKHCGLRVMGLSLITNKVSLDYSREEKVNHEEVLQISKMRAE 274
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Xenopus
Match: ube2s (ubiquitin conjugating enzyme E2 S [Source:Xenbase;Acc:XB-GENE-1008017])

HSP 1 Score: 300.827 bits (769), Expect = 4.057e-100
Identity = 142/269 (52.79%), Postives = 187/269 (69.52%), Query Frame = 3 
Query:   99 MAAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIE 905
            + A+KVGIIGG+GL+   I +  L   V TPFG PSD+L  G I +  C+L+ RHG+ HTI PTN+NYRAN+WALKS  CTH++  T CG L+   +PGD +I+DQF DRT KR QTFYDG P+   GV HIPM+EPFC +TR++LI  A ++G K H  G ++TIEGPRFSSK ES+ +   GA VINMTTVPEVILAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  +I++ +I  I   DW E L      ++
Sbjct:    4 VCAVKVGIIGGSGLDDPDILEGRLEKYVDTPFGKPSDALVLGKIKNVDCVLLARHGRQHTIAPTNVNYRANIWALKSEGCTHILVTTACGSLREEIQPGDIVIVDQFIDRTTKREQTFYDGGPSCLPGVCHIPMAEPFCAKTREVLIDIAKRLGIKCHSKGAMITIEGPRFSSKAESQMFRLWGADVINMTTVPEVILAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKATSILLTAIPQIAAMDWTELLQSMKSTVQ 272
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Xenopus
Match: ube2s (ubiquitin conjugating enzyme E2 S [Source:Xenbase;Acc:XB-GENE-1008017])

HSP 1 Score: 297.36 bits (760), Expect = 9.057e-99
Identity = 141/260 (54.23%), Postives = 183/260 (70.38%), Query Frame = 3 
Query:  114 VGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNN 893
            VGIIGG+GL+   I +  L   V TPFG PSD+L  G I +  C+L+ RHG+ HTI PTN+NYRAN+WALKS  CTH++  T CG L+   +PGD +I+DQF DRT KR QTFYDG P+   GV HIPM+EPFC +TR++LI  A ++G K H  G ++TIEGPRFSSK ES+ +   GA VINMTTVPEVILAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  +I++ +I  I   DW E L + N
Sbjct:    2 VGIIGGSGLDDPDILEGRLEKYVDTPFGKPSDALVLGKIKNVDCVLLARHGRQHTIAPTNVNYRANIWALKSEGCTHILVTTACGSLREEIQPGDIVIVDQFIDRTTKREQTFYDGGPSCLPGVCHIPMAEPFCAKTREVLIDIAKRLGIKCHSKGAMITIEGPRFSSKAESQMFRLWGADVINMTTVPEVILAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKATSILLTAIPQIAAMDWTELLQKQN 261
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Xenopus
Match: ube2s (ubiquitin conjugating enzyme E2 S [Source:Xenbase;Acc:XB-GENE-1008017])

HSP 1 Score: 295.434 bits (755), Expect = 5.080e-98
Identity = 140/257 (54.47%), Postives = 181/257 (70.43%), Query Frame = 3 
Query:  114 VGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLN 884
            VGIIGG+GL+   I +  L   V TPFG PSD+L  G I +  C+L+ RHG+ HTI PTN+NYRAN+WALKS  CTH++  T CG L+   +PGD +I+DQF DRT KR QTFYDG P+   GV HIPM+EPFC +TR++LI  A ++G K H  G ++TIEGPRFSSK ES+ +   GA VINMTTVPEVILAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  +I++ +I  I   DW E L 
Sbjct:    6 VGIIGGSGLDDPDILEGRLEKYVDTPFGKPSDALVLGKIKNVDCVLLARHGRQHTIAPTNVNYRANIWALKSEGCTHILVTTACGSLREEIQPGDIVIVDQFIDRTTKREQTFYDGGPSCLPGVCHIPMAEPFCAKTREVLIDIAKRLGIKCHSKGAMITIEGPRFSSKAESQMFRLWGADVINMTTVPEVILAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKATSILLTAIPQIAAMDWTELLQ 262
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Xenopus
Match: ube2s (ubiquitin conjugating enzyme E2 S [Source:Xenbase;Acc:XB-GENE-1008017])

HSP 1 Score: 294.664 bits (753), Expect = 9.582e-98
Identity = 140/257 (54.47%), Postives = 181/257 (70.43%), Query Frame = 3 
Query:  114 VGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLN 884
            VGIIGG+GL+   I +  L   V TPFG PSD+L  G I +  C+L+ RHG+ HTI PTN+NYRAN+WALKS  CTH++  T CG L+   +PGD +I+DQF DRT KR QTFYDG P+   GV HIPM+EPFC +TR++LI  A ++G K H  G ++TIEGPRFSSK ES+ +   GA VINMTTVPEVILAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  +I++ +I  I   DW E L 
Sbjct:    2 VGIIGGSGLDDPDILEGRLEKYVDTPFGKPSDALVLGKIKNVDCVLLARHGRQHTIAPTNVNYRANIWALKSEGCTHILVTTACGSLREEIQPGDIVIVDQFIDRTTKREQTFYDGGPSCLPGVCHIPMAEPFCAKTREVLIDIAKRLGIKCHSKGAMITIEGPRFSSKAESQMFRLWGADVINMTTVPEVILAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKATSILLTAIPQIAAMDWTELLQ 258
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Xenopus
Match: ube2s (ubiquitin conjugating enzyme E2 S [Source:Xenbase;Acc:XB-GENE-1008017])

HSP 1 Score: 294.664 bits (753), Expect = 1.020e-97
Identity = 140/257 (54.47%), Postives = 181/257 (70.43%), Query Frame = 3 
Query:  114 VGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLN 884
            VGIIGG+GL+   I +  L   V TPFG PSD+L  G I +  C+L+ RHG+ HTI PTN+NYRAN+WALKS  CTH++  T CG L+   +PGD +I+DQF DRT KR QTFYDG P+   GV HIPM+EPFC +TR++LI  A ++G K H  G ++TIEGPRFSSK ES+ +   GA VINMTTVPEVILAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  +I++ +I  I   DW E L 
Sbjct:    2 VGIIGGSGLDDPDILEGRLEKYVDTPFGKPSDALVLGKIKNVDCVLLARHGRQHTIAPTNVNYRANIWALKSEGCTHILVTTACGSLREEIQPGDIVIVDQFIDRTTKREQTFYDGGPSCLPGVCHIPMAEPFCAKTREVLIDIAKRLGIKCHSKGAMITIEGPRFSSKAESQMFRLWGADVINMTTVPEVILAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKATSILLTAIPQIAAMDWTELLQ 258
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Mouse
Match: Mtap (methylthioadenosine phosphorylase [Source:MGI Symbol;Acc:MGI:1914152])

HSP 1 Score: 294.278 bits (752), Expect = 1.277e-97
Identity = 141/271 (52.03%), Postives = 189/271 (69.74%), Query Frame = 3 
Query:  105 AIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIEQFTV 917
            A+K+GIIGGTGL+   I +      V TPFG PSD+L  G I +  C+L+ RHG+ HTI P+ +NY+AN+WALK   CTHVI  T CG L+   +PGD +I+DQF DRT+ R QTFYDG   S  GV HIPM+EPFC +TR++LI+ A ++G + H  GT+VTIEGPRFSS+ ES  +   GA V+NMTTVPEV+LAKE G+CYAS+A+ TDYD W ++E++V V  V   MK N  +  ++++ +I  I   +W ETL RN + + QF+V
Sbjct:    9 AVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDMVIIDQFIDRTSLRPQTFYDGSHCSARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTIVTIEGPRFSSRAESLIFRTWGADVVNMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDGVLKTMKENANKAKSLLLTTIPQIGSMEWSETL-RNLKNMAQFSV 278
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Mouse
Match: Pnp2 (purine-nucleoside phosphorylase 2 [Source:MGI Symbol;Acc:MGI:3712328])

HSP 1 Score: 66.2402 bits (160), Expect = 1.219e-11
Identity = 56/223 (25.11%), Postives = 101/223 (45.29%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLGI---------FQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINP---TNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVH-KSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTD 740
            +V +I G+GL  L           + ++ N   ST  G  +  L  GL++ + C+++   G+ H       + + +   ++ L  L    ++     GGL  + + GD +++    +      Q    G  +   GV    MS+ +    RQ    A  Q+GE+   + GT V + GP F +  ES+    +GA  + M+TVPEVI+A+  GL     +++T+
Sbjct:   41 QVAVICGSGLGGLTAHLKAAQIFDYNEIPNFPQSTVQGH-AGRLVFGLLNGRSCVMM--QGRFHMYEGYSLSEVTFPVRVFHL--LGVETLVVTNAAGGLNPNFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFSAWKQMGEQRKLQEGTYVMLAGPNFETVAESRLLKMLGADAVGMSTVPEVIVARHCGLRVFGFSLITN 258
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Mouse
Match: Pnp (purine-nucleoside phosphorylase [Source:MGI Symbol;Acc:MGI:97365])

HSP 1 Score: 65.855 bits (159), Expect = 1.410e-11
Identity = 61/247 (24.70%), Postives = 113/247 (45.75%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLGI---------FQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINP---TNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVH-KSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNT 812
            +V +I G+GL  L           + ++ N   ST  G  +  L  GL++ + C+++   G+ H       + + +   ++ L  L    ++     GGL  + + GD +++    +      Q    G  +   GV    MS+ +    RQ    A  Q+GE+   + GT V + GP F +  ES+    +GA  + M+TVPEVI+A+  GL     +++T+    +D E+   ++K +H+  L+ 
Sbjct:   26 QVAVICGSGLGGLTAHLKEAQIFDYNEIPNFPQSTVQGH-AGRLVFGLLNGRCCVMM--QGRFHMYEGYSLSKVTFPVRVFHL--LGVETLVVTNAAGGLNPNFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFSAWKQMGEQRKLQEGTYVMLAGPNFETVAESRLLKMLGADAVGMSTVPEVIVARHCGLRVFGFSLITN-KVVMDYEN---LEKANHMEVLDA 263
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Mouse
Match: Pnp (purine-nucleoside phosphorylase [Source:MGI Symbol;Acc:MGI:97365])

HSP 1 Score: 65.855 bits (159), Expect = 1.410e-11
Identity = 61/247 (24.70%), Postives = 113/247 (45.75%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLGI---------FQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINP---TNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVH-KSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNT 812
            +V +I G+GL  L           + ++ N   ST  G  +  L  GL++ + C+++   G+ H       + + +   ++ L  L    ++     GGL  + + GD +++    +      Q    G  +   GV    MS+ +    RQ    A  Q+GE+   + GT V + GP F +  ES+    +GA  + M+TVPEVI+A+  GL     +++T+    +D E+   ++K +H+  L+ 
Sbjct:   26 QVAVICGSGLGGLTAHLKEAQIFDYNEIPNFPQSTVQGH-AGRLVFGLLNGRCCVMM--QGRFHMYEGYSLSKVTFPVRVFHL--LGVETLVVTNAAGGLNPNFEVGDIMLIRDHINLPGFCGQNPLRGPNDERFGVRFPAMSDAYDRDMRQKAFSAWKQMGEQRKLQEGTYVMLAGPNFETVAESRLLKMLGADAVGMSTVPEVIVARHCGLRVFGFSLITN-KVVMDYEN---LEKANHMEVLDA 263
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. UniProt/SwissProt
Match: sp|Q7ZV22|MTAP_DANRE (S-methyl-5'-thioadenosine phosphorylase OS=Danio rerio OX=7955 GN=mtap PE=2 SV=2)

HSP 1 Score: 300.442 bits (768), Expect = 2.700e-99
Identity = 140/264 (53.03%), Postives = 187/264 (70.83%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNEL 899
            +K+GIIGG+GL+   I +      V TP+G PSD+L  G I +  C+L+ RHG+ HTI PTN+NY+AN+WALK   CTH++  T CG L+   +PGD +++DQF DRT KR+QTFYDGQP SP GV HIPM+EPFC +TR++L++ A  +G K H  GT+VTIEGPRFSS+ ES  + Q GA VINMTTVPEV+LAKE GLCYAS+A+ TDYD W ++E++V V  V   MK N  +  +I++ +I  I   DW  T+N +  +
Sbjct:    7 VKIGIIGGSGLDDPDILEGRTERYVVTPYGKPSDALILGKIKNVDCVLLARHGRQHTIMPTNVNYQANIWALKEEGCTHLLVTTACGSLREDIQPGDIVLIDQFIDRTTKRVQTFYDGQPTSPPGVCHIPMAEPFCSKTREVLLEVAQGLGVKCHTRGTMVTIEGPRFSSRAESLMFRQWGADVINMTTVPEVVLAKEAGLCYASIAMATDYDCWKEHEEAVCVDNVLKTMKENANKASSILLTAIPQICQMDWDSTINAHKSM 270
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. UniProt/SwissProt
Match: sp|F6V515|MTAP_XENTR (S-methyl-5'-thioadenosine phosphorylase OS=Xenopus tropicalis OX=8364 GN=mtap PE=3 SV=1)

HSP 1 Score: 296.975 bits (759), Expect = 8.183e-98
Identity = 142/270 (52.59%), Postives = 188/270 (69.63%), Query Frame = 3 
Query:   99 MAAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILI-NRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIE 905
            + A+KVGIIGG+GL+   I +  L   V TPFG PSD+L  G I +  C+L+ +RHG+ HTI PTN+NYRAN+WALKS  CTH++  T CG L+   +PGD +I+DQF DRT KR QTFYDG P+   GV HIPM+EPFC +TR++LI  A ++G K H  G ++TIEGPRFSSK ES+ +   GA VINMTTVPEVILAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  +I++ +I  I   DW E L      ++
Sbjct:    4 VCAVKVGIIGGSGLDDPDILEGRLEKYVDTPFGKPSDALVLGKIKNVDCVLLASRHGRQHTIAPTNVNYRANIWALKSEGCTHILVTTACGSLREEIQPGDIVIVDQFIDRTTKREQTFYDGGPSCLPGVCHIPMAEPFCAKTREVLIDIAKRLGIKCHSKGAMITIEGPRFSSKAESQMFRLWGADVINMTTVPEVILAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKATSILLTAIPQIAAMDWTELLQSMKSTVQ 273
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. UniProt/SwissProt
Match: sp|Q9CQ65|MTAP_MOUSE (S-methyl-5'-thioadenosine phosphorylase OS=Mus musculus OX=10090 GN=Mtap PE=1 SV=1)

HSP 1 Score: 294.278 bits (752), Expect = 8.934e-97
Identity = 141/271 (52.03%), Postives = 189/271 (69.74%), Query Frame = 3 
Query:  105 AIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIEQFTV 917
            A+K+GIIGGTGL+   I +      V TPFG PSD+L  G I +  C+L+ RHG+ HTI P+ +NY+AN+WALK   CTHVI  T CG L+   +PGD +I+DQF DRT+ R QTFYDG   S  GV HIPM+EPFC +TR++LI+ A ++G + H  GT+VTIEGPRFSS+ ES  +   GA V+NMTTVPEV+LAKE G+CYAS+A+ TDYD W ++E++V V  V   MK N  +  ++++ +I  I   +W ETL RN + + QF+V
Sbjct:    9 AVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDMVIIDQFIDRTSLRPQTFYDGSHCSARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTIVTIEGPRFSSRAESLIFRTWGADVVNMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDGVLKTMKENANKAKSLLLTTIPQIGSMEWSETL-RNLKNMAQFSV 278
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. UniProt/SwissProt
Match: sp|F6RQL9|MTAP_MACMU (S-methyl-5'-thioadenosine phosphorylase OS=Macaca mulatta OX=9544 GN=MTAP PE=3 SV=1)

HSP 1 Score: 290.041 bits (741), Expect = 3.318e-95
Identity = 138/271 (50.92%), Postives = 189/271 (69.74%), Query Frame = 3 
Query:  105 AIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIEQFTV 917
            A+K+GIIGGTGL+   I +      V TPFG PSD+L  G I +  C+L+ RHG+ HTI P+ +NY+AN+WALK   CTHVI  T CG L+   +PGD +I+DQF DRT  R Q+FYDG  +   GV HIPM+EPFC +TR++LI+ A ++G + H  GT+VTIEGPRFSS+ ES  +   GA VINMTTVPEV+LAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  ++++ +I  I   +W ETL+ N + + QF+V
Sbjct:    9 AVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLH-NLKNMAQFSV 278
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. UniProt/SwissProt
Match: sp|Q13126|MTAP_HUMAN (S-methyl-5'-thioadenosine phosphorylase OS=Homo sapiens OX=9606 GN=MTAP PE=1 SV=2)

HSP 1 Score: 290.041 bits (741), Expect = 3.318e-95
Identity = 138/271 (50.92%), Postives = 189/271 (69.74%), Query Frame = 3 
Query:  105 AIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIEQFTV 917
            A+K+GIIGGTGL+   I +      V TPFG PSD+L  G I +  C+L+ RHG+ HTI P+ +NY+AN+WALK   CTHVI  T CG L+   +PGD +I+DQF DRT  R Q+FYDG  +   GV HIPM+EPFC +TR++LI+ A ++G + H  GT+VTIEGPRFSS+ ES  +   GA VINMTTVPEV+LAKE G+CYAS+A+ TDYD W ++E++V V +V   +K N  +  ++++ +I  I   +W ETL+ N + + QF+V
Sbjct:    9 AVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLH-NLKNMAQFSV 278
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. TrEMBL
Match: A0A3P8UQ83 (S-methyl-5'-thioadenosine phosphorylase OS=Cynoglossus semilaevis OX=244447 GN=MTAP PE=3 SV=1)

HSP 1 Score: 306.605 bits (784), Expect = 3.171e-99
Identity = 144/262 (54.96%), Postives = 191/262 (72.90%), Query Frame = 3 
Query:   99 MAAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLN 884
            MA++K+GIIGG+GL+   I        V TP+G PSD+L  G I+D  C+L++RHG+NHTI PT++NY+AN+WALK   C+H++  T CG L+   KPGD +I+DQF DRT KR QT YDGQ  SP GV HIPM+EPFC+RTR++L++ A  +G K H  GTV+TIEGPRFS++ ES  + Q GA VINMTTVPEV+LAKE GLCYAS+A+ TD+D W D+E+SV V  V   MK N+ +  +I++ +I LI+D DW  T+ 
Sbjct:    4 MASVKIGIIGGSGLDDPDILDGRKEVYVDTPYGKPSDALILGKINDVDCVLLSRHGRNHTIMPTDVNYQANIWALKEQGCSHLLVTTACGSLREEIKPGDIVIIDQFIDRTTKRAQTLYDGQETSPAGVCHIPMAEPFCKRTREVLVEVAQSLGIKCHVRGTVLTIEGPRFSTRAESLMFRQWGAEVINMTTVPEVVLAKEAGLCYASIAMATDFDCWKDHEESVCVDNVLKTMKENSNKASSILLSAIPLISDMDWTHTIQ 265
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. TrEMBL
Match: A0A2T7NQY1 (S-methyl-5'-thioadenosine phosphorylase OS=Pomacea canaliculata OX=400727 GN=C0Q70_16853 PE=3 SV=1)

HSP 1 Score: 305.834 bits (782), Expect = 5.262e-99
Identity = 138/264 (52.27%), Postives = 188/264 (71.21%), Query Frame = 3 
Query:   99 MAAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRN 890
            MA +K+GIIGG+GL+   + +  +   V TP+G PSD+L  G I    C+L+ RHG+ H+I+P+N+NYRAN++ALK   C+H++  T CG LQ +  PG+ +++DQF DRT +RI+TFYDG P +P G+ HIPM+EPFC+RTR+IL      +G   HK GT++TIEGPRFSSK ESK W   GA VINM+TVPEV+LAKE GLCYASLA+VTDYDSW D+ ++VHV+      K N  +   +++ +I  I +EDW +TL  N
Sbjct:    1 MAKVKIGIIGGSGLDNPSLLENRMEKLVDTPYGKPSDALIIGTISGIDCVLLARHGRKHSISPSNVNYRANIYALKQEGCSHILVTTACGSLQENIHPGEIVVIDQFIDRTKRRIETFYDGSPEAPKGICHIPMNEPFCKRTREILSTCLEDLGLSHHKYGTMITIEGPRFSSKAESKLWRSWGAHVINMSTVPEVVLAKEAGLCYASLALVTDYDSWRDDTEAVHVELAVSTFKENAVKACKVLLAAIPHIAEEDWTDTLAEN 264
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. TrEMBL
Match: A0A3P8URR4 (S-methyl-5'-thioadenosine phosphorylase OS=Cynoglossus semilaevis OX=244447 GN=MTAP PE=3 SV=1)

HSP 1 Score: 305.834 bits (782), Expect = 7.193e-99
Identity = 144/262 (54.96%), Postives = 191/262 (72.90%), Query Frame = 3 
Query:   99 MAAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLN 884
            MA++K+GIIGG+GL+   I        V TP+G PSD+L  G I+D  C+L++RHG+NHTI PT++NY+AN+WALK   C+H++  T CG L+   KPGD +I+DQF DRT KR QT YDGQ  SP GV HIPM+EPFC+RTR++L++ A  +G K H  GTV+TIEGPRFS++ ES  + Q GA VINMTTVPEV+LAKE GLCYAS+A+ TD+D W D+E+SV V  V   MK N+ +  +I++ +I LI+D DW  T+ 
Sbjct:    4 MASVKIGIIGGSGLDDPDILDGRKEVYVDTPYGKPSDALILGKINDVDCVLLSRHGRNHTIMPTDVNYQANIWALKEQGCSHLLVTTACGSLREEIKPGDIVIIDQFIDRTTKRAQTLYDGQETSPAGVCHIPMAEPFCKRTREVLVEVAQSLGIKCHVRGTVLTIEGPRFSTRAESLMFRQWGAEVINMTTVPEVVLAKEAGLCYASIAMATDFDCWKDHEESVCVDNVLKTMKENSNKASSILLSAIPLISDMDWTHTIQ 265
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. TrEMBL
Match: A0A0X3P0C4 (S-methyl-5'-thioadenosine phosphorylase OS=Schistocephalus solidus OX=70667 GN=TR19673 PE=3 SV=1)

HSP 1 Score: 302.753 bits (774), Expect = 1.600e-97
Identity = 150/284 (52.82%), Postives = 198/284 (69.72%), Query Frame = 3 
Query:   99 MAAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQV--------------GEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIEQ 908
            MA++K+GIIGG+GL+   I +      VSTPFG+PSD+L++G I   PC+L+ RHG+ H+I P N+N+RAN+WALKSL CTHV+A   CGGLQ HT+PGD ++LDQFFDRT  RI TFYDG+P SP GV+H+P + PFC  TRQI+I+A  +               G  +H SG+ VTIEGPRFSS  ES+ ++  G  VINMT VPEV+LAKE GLCY+S+AIVTD+DSW  +E  V V+ V    K + E V NII+E+I+L+  +DW + + +   L EQ
Sbjct:    1 MASLKIGIIGGSGLDDPEILENQKEIHVSTPFGEPSDALREGTISGVPCVLLARHGRKHSIMPANVNFRANIWALKSLGCTHVLASNACGGLQEHTRPGDLVVLDQFFDRTQGRISTFYDGKPGSPVGVVHLPCATPFCPETRQIMIEAGRKYVSNVYEPGKPRTAEGPYLHTSGSCVTIEGPRFSSCCESRIFHSWGLDVINMTLVPEVVLAKEAGLCYSSIAIVTDFDSWKASEIPVSVEVVISNFKKSAETVKNIIVEAIQLLKTKDWTDLVRKTQALAEQ 284
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. TrEMBL
Match: E3TFK1 (S-methyl-5'-thioadenosine phosphorylase OS=Ictalurus punctatus OX=7998 GN=MTAP PE=2 SV=1)

HSP 1 Score: 302.368 bits (773), Expect = 1.748e-97
Identity = 142/266 (53.38%), Postives = 191/266 (71.80%), Query Frame = 3 
Query:  102 AAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNEL 899
            A +K+GIIGG+GL+   I +      V TPFG PSD+L  G I D  C+L+ RHG+ HTI P+N+NYRAN+WALK  KCTH++A T CG L+   +PGD +++DQF DRT KR QTFYDG+ +SP GV HIPM+EPFC RTR++L +AA  +G   H SGT++ IEGPRFSS+ ES  + Q GA VINMTTVPEV+LAKE GLCYA++A+ TDYD W  +E++V V  V   MK N  +  +I++ +I LI+  +W ET++++  +
Sbjct:    5 APVKIGIIGGSGLDDPDILEDRTERYVETPFGKPSDALILGKIRDVECVLLARHGRKHTIMPSNVNYRANVWALKEEKCTHILATTACGSLRDEIRPGDIVLIDQFIDRTTKRAQTFYDGELSSPPGVSHIPMAEPFCSRTREVLNEAARSLGVSFHASGTMMCIEGPRFSSRAESLMFRQWGADVINMTTVPEVMLAKEAGLCYAAVAMATDYDCWKQHEEAVCVDNVLKTMKENANKASSILLTTIPLISQVNWEETISQHRAM 270
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Cavefish
Match: mtap (methylthioadenosine phosphorylase [Source:NCBI gene;Acc:111189394])

HSP 1 Score: 271.166 bits (692), Expect = 1.311e-87
Identity = 132/257 (51.36%), Postives = 174/257 (67.70%), Query Frame = 3 
Query:  114 VGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLN 884
            +GIIGG+GL+   I +      V TPFG    +L  G I +  C+L+ RHG+ HTI P+N+NYRAN+WALK   CTHV+  T CG L+   +PGD ++LDQF DRT KR QTF DG   SP GV HIPM++PFC RTR++L+     +G + H  GT++TIEGPRFSS+ ES  + Q GA VINMTTVPEV+LAKE GLCYAS+A+ TDYD W ++E++V V  V   MK N  +  +I++ +I  I   DW  T++
Sbjct:   10 IGIIGGSGLDDPDILENRTERFVETPFG--KTALITGKIKNVECVLLARHGRQHTIMPSNVNYRANIWALKQEGCTHVVVTTACGSLRDDIQPGDIVLLDQFIDRTTKRDQTFCDGSSCSPPGVCHIPMADPFCSRTREVLLDVVKGLGIRYHPRGTMLTIEGPRFSSRAESLMFRQWGADVINMTTVPEVVLAKEAGLCYASIAMATDYDCWKEHEEAVCVDNVLKTMKENANKASSILLTAIPQIFQMDWEHTIS 264
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Cavefish
Match: mtap (methylthioadenosine phosphorylase [Source:NCBI gene;Acc:111189394])

HSP 1 Score: 252.292 bits (643), Expect = 1.095e-81
Identity = 122/231 (52.81%), Postives = 160/231 (69.26%), Query Frame = 3 
Query:  204 SDSLQQGLIHDK----PCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLN 884
            S++LQ  LI  K     C+L+ RHG+ HTI P+N+NYRAN+WALK   CTHV+  T CG L+   +PGD ++LDQF DRT KR QTF DG   SP GV HIPM++PFC RTR++L+     +G + H  GT++TIEGPRFSS+ ES  + Q GA VINMTTVPEV+LAKE GLCYAS+A+ TDYD W ++E++V V  V   MK N  +  +I++ +I  I   DW  T++
Sbjct:   18 SENLQTALITGKIKNVECVLLARHGRQHTIMPSNVNYRANIWALKQEGCTHVVVTTACGSLRDDIQPGDIVLLDQFIDRTTKRDQTFCDGSSCSPPGVCHIPMADPFCSRTREVLLDVVKGLGIRYHPRGTMLTIEGPRFSSRAESLMFRQWGADVINMTTVPEVVLAKEAGLCYASIAMATDYDCWKEHEEAVCVDNVLKTMKENANKASSILLTAIPQIFQMDWEHTIS 248
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Cavefish
Match: pnp4b (purine nucleoside phosphorylase 4b [Source:ZFIN;Acc:ZDB-GENE-040426-1887])

HSP 1 Score: 68.5514 bits (166), Expect = 1.329e-12
Identity = 63/270 (23.33%), Postives = 123/270 (45.56%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLG---------IFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTI---NPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSW-LDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIET 878
            K+ ++ G+GL  L           ++ + N  VST  G     L  G + DK C+ +   G+ H     +   + +   ++ L  ++   +I     GGL    K GD +I+    D  N  +  F    P    G+    MS+ + +  R++ +  ++++G     + G    + GP F +  E++  + +G+  + M+TVPEV +AK  GL    L+++T+  S     E+ V+ ++V H+ K+  E +  ++   I   + E+ I +
Sbjct:   31 KIAVVCGSGLGLLADNISNKQVFRYEDIPNFPVSTVPGHEGH-LVFGHVRDKSCVFMQ--GRFHLYEGYSLCRVTFPVRIFKLMGVET--IIVTNASGGLCQDFKVGDIMIIK---DHIN--LPGFAGQHPLCGFGIRFPCMSDAYSKDLRKLTLDISSELGYSNFVREGVYCMVSGPNFETIAEARMLHILGSDSVGMSTVPEVTVAKHCGLRVLGLSLITNKVSLDYSREEKVNHEEVLHISKMRAEMLQKVLYTFITRSHQEEAINS 290
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Cavefish
Match: pnp5b (purine nucleoside phosphorylase-like [Source:NCBI gene;Acc:111194529])

HSP 1 Score: 61.6178 bits (148), Expect = 2.766e-10
Identity = 60/228 (26.32%), Postives = 97/228 (42.54%), Query Frame = 3 
Query:  114 VGIIGGTGLNKLGIF---QKVLN-SDV-----STPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNIN-YRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVT-----DYDS 749
            VGI+ G+GL  L      QK+ N  D+     ST  G  +  L  G +  KPC+ +   G+ H      I      +   K +    VI     GGL    K GD +I+    +           G      G     MS+ +  + +Q+  +  A++G     + G    + GP F +  E +   ++GA  + M+TV EVI+A+  G+   +L+++T     DYDS
Sbjct:   31 VGIVCGSGLGGLADMLKDQKIFNYGDIPNFPKSTVHGH-AGRLVFGTLKGKPCVCM--QGRFHLYEGYPIQKITMPMRIFKLMGVKTVILTNAAGGLNQDYKVGDVMIIKDHINMPGFAGINPLSGPNEESFGTRFPCMSDAYDRKLQQLAQEVGAELGYSDFLREGVYCVLGGPSFETIAECRMLTRLGADAVGMSTVHEVIVARHCGMQVFALSLITNQAVMDYDS 255
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Cavefish
Match: pnp5b (purine nucleoside phosphorylase-like [Source:NCBI gene;Acc:111194529])

HSP 1 Score: 61.6178 bits (148), Expect = 4.467e-10
Identity = 60/228 (26.32%), Postives = 97/228 (42.54%), Query Frame = 3 
Query:  114 VGIIGGTGLNKLGIF---QKVLN-SDV-----STPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNIN-YRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVT-----DYDS 749
            VGI+ G+GL  L      QK+ N  D+     ST  G  +  L  G +  KPC+ +   G+ H      I      +   K +    VI     GGL    K GD +I+    +           G      G     MS+ +  + +Q+  +  A++G     + G    + GP F +  E +   ++GA  + M+TV EVI+A+  G+   +L+++T     DYDS
Sbjct:  121 VGIVCGSGLGGLADMLKDQKIFNYGDIPNFPKSTVHGH-AGRLVFGTLKGKPCVCMQ--GRFHLYEGYPIQKITMPMRIFKLMGVKTVILTNAAGGLNQDYKVGDVMIIKDHINMPGFAGINPLSGPNEESFGTRFPCMSDAYDRKLQQLAQEVGAELGYSDFLREGVYCVLGGPSFETIAECRMLTRLGADAVGMSTVHEVIVARHCGMQVFALSLITNQAVMDYDS 345
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Sea Lamprey
Match: PNP (purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:HGNC:7892])

HSP 1 Score: 52.373 bits (124), Expect = 2.857e-8
Identity = 39/154 (25.32%), Postives = 69/154 (44.81%), Query Frame = 3 
Query:  285 PTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG--EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTD 740
            P+ I Y   ++ L  ++   +I     GGL    K GD +++    +           G  +   GV    +S+ +    R+   + AAQ+G  E VH+ G +    GP + +  ES+     GA  + M+T+PE + A   GL   +L ++T+
Sbjct:    2 PSQITYPVRVFKLMGIE--TLILTNAAGGLNPDYKAGDIMLVRDHINLPGLMGLNPLVGPNDERLGVRFPCLSDTYDPALRRACSRVAAQLGVTELVHE-GVLCMQTGPCYETVAESRLLRAFGADAVGMSTLPEAVCAYHCGLRVLALTLITN 152
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Sea Lamprey
Match: PNP (purine nucleoside phosphorylase [Source:HGNC Symbol;Acc:HGNC:7892])

HSP 1 Score: 52.7582 bits (125), Expect = 4.649e-8
Identity = 62/255 (24.31%), Postives = 105/255 (41.18%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLGIFQKVLNSDVSTPFGD----PSDSLQQ-------GLIHDKPCILINRHGKNHTINPTNIN-YRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPN-SPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVH-----KSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERV 821
            KVG++ G+GL  L     +L    S P+ D    P  +++        G +  K C+ +   G+ H     +++     +   K L    ++     GGL    K GD +I+     R +  +       P   PN     P      +   + L   A +VG  +      + G  V   GP F S  E +    +GA  + M+TVPEV++AK  GL    ++++T+ ++ LD E     +  +H   L T R+
Sbjct:   30 KVGMVLGSGLGGLA---DMLEDQQSFPYSDIPNFPPGAVEGHVGRLVFGQLSGKTCVCM--QGRFHAYEGYSMSKVTFPIRVFKLLGVDTMVVTNAAGGLNKQYKVGDIMII-----RDHINLPGLAGNNPLLGPNIEKFGPRFPSVSDAYDRSLCALAKKVGTTLGFGEFLREGVYVMNTGPAFESIAECRMMVILGADAVGMSTVPEVLIAKHCGLRVLGISLITN-EAILDYETE---KTANHAEVLETGRM 270
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Yeast
Match: MEU1 (Methylthioadenosine phosphorylase (MTAP); catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression [Source:SGD;Acc:S000004007])

HSP 1 Score: 140.198 bits (352), Expect = 1.209e-38
Identity = 86/242 (35.54%), Postives = 128/242 (52.89%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKV-LNSDVSTPFGDPSD--SLQQ--GLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNK-RIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-----EKVH----KSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKV 788
            + +GIIGGTGL  L   + + L   + TP+G  S   ++ Q  G         I RHG NH   PT + +RAN+ ALK+L C  V++ +  G LQ H KP DF++  Q  DRT   R  +++    N    V H+   +PF ++  + + +   ++      E  H    K  TVV +EGP+FS++ ESK +   G  VINM+ +PE  LA+E  L Y  + + TDYD+W D  + V V+ V
Sbjct:   33 VDLGIIGGTGLYNLDCLEPIALLPPMVTPWGTTSSPVTISQFVGTNSHFHVAFIARHGINHEYPPTKVPFRANMAALKNLNCKAVLSFSAVGSLQPHIKPRDFVLPQQIIDRTKGIRHSSYF----NDEGLVGHVGFGQPFSQKFAEYIYQFKNEITNPESEEPCHLHYDKDMTVVCMEGPQFSTRAESKMYRMFGGHVINMSVIPEAKLARECELPYQMICMSTDYDAWRDEAEPVTVETV 270
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Yeast
Match: PNP1 (Purine nucleoside phosphorylase; specifically metabolizes inosine and guanosine nucleosides; involved in the nicotinamide riboside salvage pathway [Source:SGD;Acc:S000004199])

HSP 1 Score: 51.2174 bits (121), Expect = 9.631e-8
Identity = 55/226 (24.34%), Postives = 103/226 (45.58%), Query Frame = 3 
Query:  120 IIGGTGLNKLGIFQKVLNSD---VSTPFGD-----------PSDSLQQGLIHDKPCILIN--RHG-KNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKA--AAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTD 740
            II G+GL   GI  K+   +   V+ P+ D            S +L  G ++  P +L+N   HG + +T+  T    R  L  +  ++  ++I     GG+ +  +  D + +    +      Q    G     +G   + +S+ +    R++L K     ++   +H+ GT   + GP F ++ ESK    +G   + M+TVPEVI+A+  G    +L+++T+
Sbjct:   42 IICGSGLG--GISTKLSRDNPPPVTVPYQDIPGFKKSTVPGHSGTLMFGSMNGSPVVLMNGRLHGYEGNTLFETTFPIRV-LNHMGHVR--NLIVTNAAGGINAKYQACDLMCIYDHLNIPGLAGQHPLRGPNLDEDGPRFLALSDAYDLELRKLLFKKWKELKIQRPLHE-GTYTFVSGPTFETRAESKMIRMLGGDAVGMSTVPEVIVARHCGWRVLALSLITN 261
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Nematostella
Match: EDO34894 (S-methyl-5'-thioadenosine phosphorylase [Source:UniProtKB/Swiss-Prot;Acc:A7SN31])

HSP 1 Score: 261.922 bits (668), Expect = 2.325e-85
Identity = 128/266 (48.12%), Postives = 168/266 (63.16%), Query Frame = 3 
Query:  108 IKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIE 905
            +K+GIIGGTG++   I        V TPFG PS+ L  G I    C+LI RHG+ HT+ PT+INYRAN+WALK   CTH++  T CG L    +PG+ +  DQ  DRT KR  TFYDGQ NSP GV HIPM +P+C  T+QIL   A ++G   H SG  V IEGPRFS++ ES+ +  +G  +I+MT +PEV LA E GLCYA++A+VTDYD W D+   V V+ V    K+N    I I+I +I  I  +DW E +N     ++
Sbjct:    6 VKIGIIGGTGVDNPNIMTDRQEKFVDTPFGKPSEPLITGNIQGVECVLIARHGRKHTVMPTDINYRANVWALKEEGCTHIVVTTACGSLTEAYRPGEIVFPDQIIDRTTKRPSTFYDGQTNSPVGVCHIPMHDPYCSVTKQILANEAQKLGIPHHASGVNVVIEGPRFSTRAESRMFRGLGGEIISMTAMPEVALANEAGLCYAAIAMVTDYDCWRDDHAPVTVESVIATFKVNVANAIKILIAAIPEIAAKDWTEIINERKSQVK 271
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Nematostella
Match: EDO25890 (Purine nucleoside phosphorylase [Source:UniProtKB/TrEMBL;Acc:A7TDF4])

HSP 1 Score: 65.0846 bits (157), Expect = 5.839e-12
Identity = 45/157 (28.66%), Postives = 77/157 (49.04%), Query Frame = 3 
Query:  312 LWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVH---KSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSV 773
            +  +K L    VI     GG+ S  + GD +I+    D  N   +    G  +   G   + MSEP+ +     +I  A ++ + +    K G  ++++GP F +  E K    MGA  + M+TVPEVI+AK + +    L+++TD    + NE+S+
Sbjct:   95 IRVMKQLGIEKVIVSNASGGVNSTFQVGDIMIIK---DHINMMPEHPLRGHNDERFGPRFVNMSEPYSKN----MIAKAKEIAKTLDIDVKEGIYLSLQGPTFETLAEYKMVKSMGADCVGMSTVPEVIVAKHMNMDCFGLSVITD----MGNEESL 240
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Nematostella
Match: EDO40518 (Purine nucleoside phosphorylase [Source:UniProtKB/TrEMBL;Acc:A7S700])

HSP 1 Score: 48.521 bits (114), Expect = 2.034e-6
Identity = 53/250 (21.20%), Postives = 107/250 (42.80%), Query Frame = 3 
Query:  114 VGIIGGTGLNKLG---------IFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHT---INPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYD--SWLDNEDSVHVQKVSHVMKLNTER 818
            +G+I G+GL+ LG          ++K+     ST  G     L  G ++    +++   G+ H     +P  I     +     +K  H++     GGL+     GD +++    +       +   G  +S  G+    +S+ + +  +++ ++ A+++G     ++G      GP F +  E +F    G   + M+TV EV +A+  G+    ++++T+     + DNE     Q  +H   L T R
Sbjct:   38 IGVICGSGLSSLGDLVTEKTVIPYEKIPQFPRSTVPGH-QGQLVFGRLNGTTVVMM--QGRTHLYEGYDPGQITLPVRVMVHLGIK--HLVVTNAAGGLRQDWNVGDIMVIKDHINLAGLTGLSPLRGCNDSRFGLRFPALSDAYNKDLQKLALETASELGFADFTRTGVYCAQVGPCFETPAECRFLQNAGVDAVGMSTVHEVSVARHAGVTVLGISLITNIAVLGYGDNE-----QPANHDEVLETGR 277
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Medaka
Match: mtap (methylthioadenosine phosphorylase [Source:NCBI gene;Acc:101167850])

HSP 1 Score: 273.478 bits (698), Expect = 1.025e-89
Identity = 126/235 (53.62%), Postives = 169/235 (71.91%), Query Frame = 3 
Query:  177 DVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETL 881
            ++S     PSD+L  G I +  C+L+ RHG+ HTI P+N+NYRAN+WAL+   CTH++  T CG L+   +PGD +I+DQF DRT KR QT YDGQP+SP GV HIPM+EPFC RTR++L++ A  +G K H  GT++TIEGPRFSS+ ES  + Q GA VINMTTVPEV+LAKE GLCYAS+A+ TDYD W ++E++V V  V   MK N  +  +I++ +I  I+  DW +T+
Sbjct:   27 NISVSNEKPSDALILGKIKNVECVLLARHGRQHTIMPSNVNYRANIWALREEGCTHLLVTTACGSLREEIQPGDIVIIDQFIDRTTKRHQTLYDGQPSSPPGVCHIPMAEPFCSRTREVLVEVARSLGVKCHHRGTMLTIEGPRFSSRAESLMFRQWGADVINMTTVPEVVLAKEAGLCYASIAMATDYDCWKEHEEAVCVDNVLKTMKENANKASSILLTAIPHISQVDWTQTI 261
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Medaka
Match: pnp4b (purine nucleoside phosphorylase [Source:NCBI gene;Acc:101168443])

HSP 1 Score: 65.4698 bits (158), Expect = 1.463e-11
Identity = 62/270 (22.96%), Postives = 118/270 (43.70%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLG---------IFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRH---GKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSW-LDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIET 878
            KV II G+GL  L           +Q + N  +ST  G     L  G I D+ C+ +  H    + +T+    + +   ++ L  ++   V+     GG+    K GD +I+    +      Q    G  +   G+    MS+ + +  R +++  + ++G     + G    + GP F +  E++    +G   + M+ VPEV +AK  GL   +L+++T+  S     E+ V+ ++V  + K+  E +  ++   I   N +  I T
Sbjct:   30 KVAIICGSGLGLLADGASNKQTFRYQDIPNFPISTVPGH-DGCLVFGTIEDRSCVFMKGHFHLYEGYTL--CQVTFPVRIFKLMGVE--LVLVTNASGGICPDFKVGDIMIIKDHINLPGFAGQHPLCGPNDERFGIRFPCMSDAYSKDMRSVVVDISTELGCSDFIREGVYCMVSGPNFETIAEARMLWILGCDSVGMSMVPEVTVAKHCGLQVVALSLITNKVSLDYSREEKVNHEEVLEICKMRAELLQKLVTSLISRFNQQQIINT 294
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Medaka
Match: pnp6 (purine nucleoside phosphorylase [Source:NCBI gene;Acc:101165730])

HSP 1 Score: 63.5438 bits (153), Expect = 7.215e-11
Identity = 60/233 (25.75%), Postives = 100/233 (42.92%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLGIFQKVLNSDVSTPFGD----PSDSLQQ-------GLIHDKPCILINRHGKNHTINPTNIN---YRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVT-----DYDS 749
            KV II G+GL  L     +L      P+GD    PS ++Q        G +    C+ +   G+ H     +I+   Y   ++ L  +K   +I     GGL +    GD +++    +      Q    G  +   GV    MS+ +    R +  K A + G     + G    + GP + +  ES+    +GA  + M+TVPEV++A+  GL    L+++T     DY+S
Sbjct:   29 KVAIICGSGLGGLA---DLLEDKTVFPYGDIPSFPSSTVQGHAGQLVFGKLQGCECVCMK--GRFHFYEGYSIHTVTYPVRVFRLLGVKT--LIVTNAAGGLNAAFNVGDIMLIKDHINMPGFAGQNPLCGHNDDRFGVRFPCMSDAYDRDLRALAKKTAKEQGCNSFLQEGVYCMLAGPTYETIAESRVLQILGADAVGMSTVPEVVVARHCGLRVLGLSLITNKVVMDYES 254
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Medaka
Match: pnp6 (purine nucleoside phosphorylase [Source:NCBI gene;Acc:101165730])

HSP 1 Score: 63.5438 bits (153), Expect = 7.653e-11
Identity = 60/233 (25.75%), Postives = 100/233 (42.92%), Query Frame = 3 
Query:  111 KVGIIGGTGLNKLGIFQKVLNSDVSTPFGD----PSDSLQQ-------GLIHDKPCILINRHGKNHTINPTNIN---YRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVT-----DYDS 749
            KV II G+GL  L     +L      P+GD    PS ++Q        G +    C+ +   G+ H     +I+   Y   ++ L  +K   +I     GGL +    GD +++    +      Q    G  +   GV    MS+ +    R +  K A + G     + G    + GP + +  ES+    +GA  + M+TVPEV++A+  GL    L+++T     DY+S
Sbjct:   35 KVAIICGSGLGGLA---DLLEDKTVFPYGDIPSFPSSTVQGHAGQLVFGKLQGCECVCMK--GRFHFYEGYSIHTVTYPVRVFRLLGVK--TLIVTNAAGGLNAAFNVGDIMLIKDHINMPGFAGQNPLCGHNDDRFGVRFPCMSDAYDRDLRALAKKTAKEQGCNSFLQEGVYCMLAGPTYETIAESRVLQILGADAVGMSTVPEVVVARHCGLRVLGLSLITNKVVMDYES 260
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Medaka
Match: ENSORLT00000003413.2 (purine nucleoside phosphorylase [Source:NCBI gene;Acc:101162955])

HSP 1 Score: 62.7734 bits (151), Expect = 1.380e-10
Identity = 67/252 (26.59%), Postives = 102/252 (40.48%), Query Frame = 3 
Query:  114 VGIIGGTGLNKLG---------IFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNIN-YRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVG-EKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGL-CYASLAI----VTDYDSWLDNEDSVHVQKVSHVMKLNTERV 821
            VGI+ G+GL  L           +  + N   ST  G  +  L  G +  KPC+ +   G+ H      I      +   K L    +I     GGL    K GD +I+    +           G  +   GV    MS+ +    RQ+    AA++G     + G    + GP F +  E +  + +GA  + M+TV EVI+A+  G+ C+A   I    V DYDS          +K +H   L T R+
Sbjct:   32 VGIVCGSGLGGLAEMLKDPQVFKYSDIPNFPRSTVHGH-AGQLVFGTLKGKPCVCM--QGRFHLYEGYPIQKITLPMRVFKLLGVETMIMTNAAGGLNQDYKVGDVMIIKDHINMPGFAGINPLAGPNDDRFGVRFPCMSDAYDRELRQLAHDVAAELGYSDFLQEGVYCVLGGPSFETIAECRMLHSLGADAVGMSTVHEVIVARHAGMRCFALSLISNRSVMDYDSQ---------EKANHEEVLETGRL 271
[Close]
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Planmine SMEST
Match: SMESG000016252.1 (SMESG000016252.1)

HSP 1 Score: 543.117 bits (1398), Expect = 0.000e+0
Identity = 273/273 (100.00%), Postives = 273/273 (100.00%), Query Frame = 3 
Query:   99 MAAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIEQFTV 917
            MAAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVINIIIESIKLINDEDWIETLNRNNELIEQFTV
Sbjct:    1 MAAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCILINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGDFIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVINIIIESIKLINDEDWIETLNRNNELIEQFTV 273
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Planmine SMEST
Match: SMESG000016252.1 (SMESG000016252.1)

HSP 1 Score: 264.618 bits (675), Expect = 2.311e-88
Identity = 140/140 (100.00%), Postives = 140/140 (100.00%), Query Frame = 3 
Query:  498 MSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVXXXXXXXXXXXNDEDWIETLNRNNELIEQFTV 917
            MSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVINIIIESIKLINDEDWIETLNRNNELIEQFTV
Sbjct:    1 MSEPFCERTRQILIKAAAQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAKELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVINIIIESIKLINDEDWIETLNRNNELIEQFTV 140
The following BLAST results are available for this feature:
BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MTAP6.910e-9650.92methylthioadenosine phosphorylase [Source:HGNC Sym... [more]
MTAP4.435e-9450.56methylthioadenosine phosphorylase [Source:HGNC Sym... [more]
MTAP1.421e-9351.54methylthioadenosine phosphorylase [Source:HGNC Sym... [more]
MTAP1.165e-9054.91methylthioadenosine phosphorylase [Source:HGNC Sym... [more]
AL359922.11.209e-3553.21novel transcript[more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
B0228.77.730e-6843.54S-methyl-5'-thioadenosine phosphorylase [Source:U... [more]
B0228.77.730e-6843.54S-methyl-5'-thioadenosine phosphorylase [Source:U... [more]
B0228.77.730e-6843.54S-methyl-5'-thioadenosine phosphorylase [Source:U... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Mtap8.365e-8648.84gene:FBgn0034215 transcript:FBtr0086916[more]
Mtap8.365e-8648.84gene:FBgn0034215 transcript:FBtr0345803[more]
Mtap7.344e-8548.84gene:FBgn0034215 transcript:FBtr0329993[more]
CG311152.317e-6840.38gene:FBgn0051115 transcript:FBtr0290053[more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtap3.577e-10053.03methylthioadenosine phosphorylase [Source:NCBI gen... [more]
pnp62.382e-1125.20purine nucleoside phosphorylase 6 [Source:ZFIN;Acc... [more]
pnp62.382e-1125.20purine nucleoside phosphorylase 6 [Source:ZFIN;Acc... [more]
pnp5a5.654e-1124.21purine nucleoside phosphorylase 5a [Source:ZFIN;Ac... [more]
pnp4b9.169e-1123.60purine nucleoside phosphorylase 4b [Source:ZFIN;Ac... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ube2s4.057e-10052.79ubiquitin conjugating enzyme E2 S [Source:Xenbase;... [more]
ube2s9.057e-9954.23ubiquitin conjugating enzyme E2 S [Source:Xenbase;... [more]
ube2s5.080e-9854.47ubiquitin conjugating enzyme E2 S [Source:Xenbase;... [more]
ube2s9.582e-9854.47ubiquitin conjugating enzyme E2 S [Source:Xenbase;... [more]
ube2s1.020e-9754.47ubiquitin conjugating enzyme E2 S [Source:Xenbase;... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Mtap1.277e-9752.03methylthioadenosine phosphorylase [Source:MGI Symb... [more]
Pnp21.219e-1125.11purine-nucleoside phosphorylase 2 [Source:MGI Symb... [more]
Pnp1.410e-1124.70purine-nucleoside phosphorylase [Source:MGI Symbol... [more]
Pnp1.410e-1124.70purine-nucleoside phosphorylase [Source:MGI Symbol... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7ZV22|MTAP_DANRE2.700e-9953.03S-methyl-5'-thioadenosine phosphorylase OS=Danio r... [more]
sp|F6V515|MTAP_XENTR8.183e-9852.59S-methyl-5'-thioadenosine phosphorylase OS=Xenopus... [more]
sp|Q9CQ65|MTAP_MOUSE8.934e-9752.03S-methyl-5'-thioadenosine phosphorylase OS=Mus mus... [more]
sp|F6RQL9|MTAP_MACMU3.318e-9550.92S-methyl-5'-thioadenosine phosphorylase OS=Macaca ... [more]
sp|Q13126|MTAP_HUMAN3.318e-9550.92S-methyl-5'-thioadenosine phosphorylase OS=Homo sa... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A3P8UQ833.171e-9954.96S-methyl-5'-thioadenosine phosphorylase OS=Cynoglo... [more]
A0A2T7NQY15.262e-9952.27S-methyl-5'-thioadenosine phosphorylase OS=Pomacea... [more]
A0A3P8URR47.193e-9954.96S-methyl-5'-thioadenosine phosphorylase OS=Cynoglo... [more]
A0A0X3P0C41.600e-9752.82S-methyl-5'-thioadenosine phosphorylase OS=Schisto... [more]
E3TFK11.748e-9753.38S-methyl-5'-thioadenosine phosphorylase OS=Ictalur... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtap1.311e-8751.36methylthioadenosine phosphorylase [Source:NCBI gen... [more]
mtap1.095e-8152.81methylthioadenosine phosphorylase [Source:NCBI gen... [more]
pnp4b1.329e-1223.33purine nucleoside phosphorylase 4b [Source:ZFIN;Ac... [more]
pnp5b2.766e-1026.32purine nucleoside phosphorylase-like [Source:NCBI ... [more]
pnp5b4.467e-1026.32purine nucleoside phosphorylase-like [Source:NCBI ... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
PNP2.857e-825.32purine nucleoside phosphorylase [Source:HGNC Symbo... [more]
PNP4.649e-824.31purine nucleoside phosphorylase [Source:HGNC Symbo... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
MEU11.209e-3835.54Methylthioadenosine phosphorylase (MTAP); catalyze... [more]
PNP19.631e-824.34Purine nucleoside phosphorylase; specifically meta... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO348942.325e-8548.12S-methyl-5'-thioadenosine phosphorylase [Source:U... [more]
EDO258905.839e-1228.66Purine nucleoside phosphorylase [Source:UniProtKB... [more]
EDO405182.034e-621.20Purine nucleoside phosphorylase [Source:UniProtKB... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mtap1.025e-8953.62methylthioadenosine phosphorylase [Source:NCBI gen... [more]
pnp4b1.463e-1122.96purine nucleoside phosphorylase [Source:NCBI gene;... [more]
pnp67.215e-1125.75purine nucleoside phosphorylase [Source:NCBI gene;... [more]
pnp67.653e-1125.75purine nucleoside phosphorylase [Source:NCBI gene;... [more]
ENSORLT00000003413.21.380e-1026.59purine nucleoside phosphorylase [Source:NCBI gene;... [more]
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BLAST of S-methyl-5'-thioadenosine phosphorylase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000016252.10.000e+0100.00SMESG000016252.1[more]
SMESG000016252.12.311e-88100.00SMESG000016252.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026736 ID=SMED30026736|Name=S-methyl-5'-thioadenosine phosphorylase|organism=Schmidtea mediterranea sexual|type=transcript|length=1247bp
ATGTTTACCACCATTACATTGGTCAAATTACAACTAAGTTAATCCAAACA
AATTTTAGTAGTATTTATACACCTTTGCACTAATTGGTTTGCGTACAAAT
GGCTGCGATTAAAGTTGGCATAATTGGCGGGACAGGATTGAATAAATTAG
GTATTTTCCAAAAAGTTCTGAACAGTGATGTATCCACACCGTTTGGTGAT
CCCTCGGATAGTTTACAGCAAGGATTAATTCATGATAAACCGTGTATTCT
CATTAACAGGCATGGTAAAAATCACACAATCAACCCTACGAATATAAACT
ATCGAGCTAATTTGTGGGCATTGAAAAGCCTTAAATGTACTCATGTTATT
GCAATCACAACTTGCGGTGGTTTACAAAGCCATACGAAACCTGGAGATTT
CATAATTCTGGATCAATTTTTTGATAGAACAAATAAAAGAATCCAGACAT
TTTATGATGGGCAACCAAATTCACCAAACGGTGTTCTTCATATTCCAATG
AGTGAGCCATTTTGTGAGAGAACTCGTCAGATATTGATAAAAGCTGCTGC
ACAAGTAGGTGAGAAAGTCCATAAATCTGGAACAGTTGTTACTATAGAAG
GACCGAGGTTTTCTTCGAAATTTGAGTCGAAATTTTGGAATCAAATGGGC
GCTTCCGTCATCAATATGACAACTGTTCCTGAAGTGATTCTTGCCAAAGA
ATTGGGCTTGTGTTATGCATCTTTGGCAATCGTGACAGATTACGATAGCT
GGTTAGACAATGAGGATTCAGTGCATGTTCAGAAAGTTTCACATGTCATG
AAATTGAATACCGAGCGTGTGATAAATATTATTATTGAATCTATTAAGTT
AATTAATGACGAAGATTGGATTGAGACTCTCAATAGAAATAATGAGCTTA
TTGAGCAATTTACAGTTTGATATTCAGGTCATATTGGTTACTGTTACAAA
ATAAATTAAAAGTTTAGATGGCAGACTACCAATTCAAAATGAGCTTACCA
ATTAGCCAAATTTGATAATGTTGATGAGTTAAAACAAATGTTTTGCAATT
ATTTGTTGTTACTGAGAAAAAATACTTTAAACATTAATATTTTTAATATT
TGCCTTATAGATAAAATATTCCCTTCAATTTAGTTAAAAAATAACCATTA
TTTGGAACAATCTAATGATGTTTGGGAAAAATTTTATGTATTATTTATAA
CGGAGAAATCAAAATCTCTTAGGCAACCCAATCCATGTCTTGCTTCA
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protein sequence of SMED30026736-orf-1

>SMED30026736-orf-1 ID=SMED30026736-orf-1|Name=SMED30026736-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=274bp
MAAIKVGIIGGTGLNKLGIFQKVLNSDVSTPFGDPSDSLQQGLIHDKPCI
LINRHGKNHTINPTNINYRANLWALKSLKCTHVIAITTCGGLQSHTKPGD
FIILDQFFDRTNKRIQTFYDGQPNSPNGVLHIPMSEPFCERTRQILIKAA
AQVGEKVHKSGTVVTIEGPRFSSKFESKFWNQMGASVINMTTVPEVILAK
ELGLCYASLAIVTDYDSWLDNEDSVHVQKVSHVMKLNTERVINIIIESIK
LINDEDWIETLNRNNELIEQFTV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0002075pigment cell
PLANA:0002089reproductive organ
PLANA:0003116parenchymal cell
PLANA:0007528glial cell
Vocabulary: INTERPRO
TermDefinition
IPR010044MTAP
IPR035994Nucleoside_phosphorylase_sf
IPR000845Nucleoside_phosphorylase_d
Vocabulary: molecular function
TermDefinition
GO:0003824catalytic activity
GO:0016740transferase activity
GO:0016757transferase activity, transferring glycosyl groups
GO:0016763transferase activity, transferring pentosyl groups
GO:0017061S-methyl-5-thioadenosine phosphorylase activity
Vocabulary: biological process
TermDefinition
GO:0009116nucleoside metabolic process
GO:0006166purine ribonucleoside salvage
GO:0019509L-methionine salvage from methylthioadenosine
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR010044Methylthioadenosine phosphorylase (MTAP)TIGRFAMTIGR01694TIGR01694coord: 6..250
e-value: 2.0E-85
score: 283.9
IPR010044Methylthioadenosine phosphorylase (MTAP)PANTHERPTHR42679FAMILY NOT NAMEDcoord: 3..258
IPR000845Nucleoside phosphorylase domainPFAMPF01048PNP_UDP_1coord: 5..242
e-value: 2.0E-43
score: 148.3
IPR035994Nucleoside phosphorylase superfamilyGENE3DG3DSA:3.40.50.1580coord: 1..273
e-value: 4.9E-89
score: 300.2
IPR035994Nucleoside phosphorylase superfamilySUPERFAMILYSSF53167Purine and uridine phosphorylasescoord: 4..262
NoneNo IPR availableCDDcd09010MTAP_SsMTAPII_like_MTIPcoord: 6..249
e-value: 7.03087E-126
score: 355.575