40S ribosomal protein S19

Overview
Name40S ribosomal protein S19
Smed IDSMED30026696
Length (bp)616
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of 40S ribosomal protein S19 (SMED30026696) t-SNE clustered cells

Violin plots show distribution of expression levels for 40S ribosomal protein S19 (SMED30026696) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of 40S ribosomal protein S19 (SMED30026696) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for 40S ribosomal protein S19 (SMED30026696) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30026696

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30026696SMESG000023987.1 SMESG000009719.1 SmedASXL_004298SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
gutSMED30026696SMESG000023987.1 SMESG000009719.1 dd_Smed_v4_202_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
neoblastSMED30026696SMESG000023987.1 SMESG000009719.1 dd_Smed_v4_202_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30026696SMESG000023987.1 SMESG000009719.1 dd_Smed_v4_202_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
epidermal cellSMED30026696SMESG000023987.1 SMESG000009719.1 dd_Smed_v4_202_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
progenitor cellSMED30026696SMESG000023987.1 SMESG000009719.1 dd_Smed_v6_202_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30026696SMESG000023987.1 SMESG000009719.1 dd_Smed_v6_202_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of 40S ribosomal protein S19 vs. Ensembl Human
Match: RPS19 (ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC:10402])

HSP 1 Score: 131.339 bits (329), Expect = 1.485e-38
Identity = 65/134 (48.51%), Postives = 88/134 (65.67%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS  RHLY R   G+  +TKIY   + NG  PSH  +G+  + R  L+ L  L +VE   +  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Human
Match: RPS19 (ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC:10402])

HSP 1 Score: 131.339 bits (329), Expect = 1.485e-38
Identity = 65/134 (48.51%), Postives = 88/134 (65.67%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS  RHLY R   G+  +TKIY   + NG  PSH  +G+  + R  L+ L  L +VE   +  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Human
Match: RPS19 (ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC:10402])

HSP 1 Score: 131.339 bits (329), Expect = 1.485e-38
Identity = 65/134 (48.51%), Postives = 88/134 (65.67%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS  RHLY R   G+  +TKIY   + NG  PSH  +G+  + R  L+ L  L +VE   +  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Human
Match: RPS19 (ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC:10402])

HSP 1 Score: 75.8702 bits (185), Expect = 1.367e-17
Identity = 35/96 (36.46%), Postives = 58/96 (60.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHM-VKGNTGI 435
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R   ++  +Y  +  +       S   ++ S   H+ ++G  G+
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAGGLILSIYTEADSLGLDPSFTSGCVSSASTARHLYLRGGAGV 99          
BLAST of 40S ribosomal protein S19 vs. Ensembl Human
Match: RPS19 (ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC:10402])

HSP 1 Score: 68.1662 bits (165), Expect = 5.914e-15
Identity = 29/53 (54.72%), Postives = 41/53 (77.36%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIR 309
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R
Sbjct:    3 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTR 55          
BLAST of 40S ribosomal protein S19 vs. Ensembl Celegans
Match: rps-19 (40S ribosomal protein S19 [Source:UniProtKB/Swiss-Prot;Acc:O18650])

HSP 1 Score: 120.553 bits (301), Expect = 1.025e-34
Identity = 59/131 (45.04%), Postives = 79/131 (60.31%), Query Frame = 1
Query:  154 SVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVE--LSNQKRVLTSEGRRDLDRIA 540
            S+KD+ Q + T ++A FLK SGKV+ PEW DLVKL    ELAP D DW++ R AS+ RHLY R  GI    K+Y  NK  G  P+H        +R  ++ L  +  VE     + R+L+ +GR+DLDRIA
Sbjct:    6 SIKDVDQHEATKSIAHFLKKSGKVKVPEWSDLVKLGVNKELAPVDPDWFYTRAASLARHLYFRPAGIGAFKKVYGGNKRRGVAPNHFQTSAGNCLRKAVQQLEKIKWVEKHPDGKGRILSKQGRKDLDRIA 136          
BLAST of 40S ribosomal protein S19 vs. Ensembl Fly
Match: RpS19a (gene:FBgn0010412 transcript:FBtr0340149)

HSP 1 Score: 129.028 bits (323), Expect = 6.856e-38
Identity = 66/134 (49.25%), Postives = 88/134 (65.67%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRS-TGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVE-LSNQKRVLTSEGRRDLDRIAFQ 546
            ++VKDI Q   T A+A FLK +GK++ P+ +D+VK ++  ELAP D DW+++RCASILRHLY+RS  G+  +TKIY   K NG  PSH  +   G  R  L+ L    LVE   +  R L+S G+RDLDRIA Q
Sbjct:    4 VTVKDIDQHAVTKAVAVFLKKTGKLKVPDQMDIVKTAKFKELAPYDPDWFYVRCASILRHLYHRSPAGVGSITKIYGGRKRNGVHPSHFCRAADGAARKALQALEHARLVEKHPDGGRKLSSIGQRDLDRIANQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Fly
Match: RpS19a (gene:FBgn0010412 transcript:FBtr0345129)

HSP 1 Score: 129.028 bits (323), Expect = 6.856e-38
Identity = 66/134 (49.25%), Postives = 88/134 (65.67%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRS-TGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVE-LSNQKRVLTSEGRRDLDRIAFQ 546
            ++VKDI Q   T A+A FLK +GK++ P+ +D+VK ++  ELAP D DW+++RCASILRHLY+RS  G+  +TKIY   K NG  PSH  +   G  R  L+ L    LVE   +  R L+S G+RDLDRIA Q
Sbjct:    4 VTVKDIDQHAVTKAVAVFLKKTGKLKVPDQMDIVKTAKFKELAPYDPDWFYVRCASILRHLYHRSPAGVGSITKIYGGRKRNGVHPSHFCRAADGAARKALQALEHARLVEKHPDGGRKLSSIGQRDLDRIANQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Fly
Match: RpS19a (gene:FBgn0010412 transcript:FBtr0074311)

HSP 1 Score: 129.028 bits (323), Expect = 6.856e-38
Identity = 66/134 (49.25%), Postives = 88/134 (65.67%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRS-TGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVE-LSNQKRVLTSEGRRDLDRIAFQ 546
            ++VKDI Q   T A+A FLK +GK++ P+ +D+VK ++  ELAP D DW+++RCASILRHLY+RS  G+  +TKIY   K NG  PSH  +   G  R  L+ L    LVE   +  R L+S G+RDLDRIA Q
Sbjct:    4 VTVKDIDQHAVTKAVAVFLKKTGKLKVPDQMDIVKTAKFKELAPYDPDWFYVRCASILRHLYHRSPAGVGSITKIYGGRKRNGVHPSHFCRAADGAARKALQALEHARLVEKHPDGGRKLSSIGQRDLDRIANQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Fly
Match: RpS19a (gene:FBgn0010412 transcript:FBtr0074312)

HSP 1 Score: 129.028 bits (323), Expect = 6.856e-38
Identity = 66/134 (49.25%), Postives = 88/134 (65.67%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRS-TGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVE-LSNQKRVLTSEGRRDLDRIAFQ 546
            ++VKDI Q   T A+A FLK +GK++ P+ +D+VK ++  ELAP D DW+++RCASILRHLY+RS  G+  +TKIY   K NG  PSH  +   G  R  L+ L    LVE   +  R L+S G+RDLDRIA Q
Sbjct:    4 VTVKDIDQHAVTKAVAVFLKKTGKLKVPDQMDIVKTAKFKELAPYDPDWFYVRCASILRHLYHRSPAGVGSITKIYGGRKRNGVHPSHFCRAADGAARKALQALEHARLVEKHPDGGRKLSSIGQRDLDRIANQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Fly
Match: RpS19a (gene:FBgn0010412 transcript:FBtr0074313)

HSP 1 Score: 129.028 bits (323), Expect = 6.856e-38
Identity = 66/134 (49.25%), Postives = 88/134 (65.67%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRS-TGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVE-LSNQKRVLTSEGRRDLDRIAFQ 546
            ++VKDI Q   T A+A FLK +GK++ P+ +D+VK ++  ELAP D DW+++RCASILRHLY+RS  G+  +TKIY   K NG  PSH  +   G  R  L+ L    LVE   +  R L+S G+RDLDRIA Q
Sbjct:    4 VTVKDIDQHAVTKAVAVFLKKTGKLKVPDQMDIVKTAKFKELAPYDPDWFYVRCASILRHLYHRSPAGVGSITKIYGGRKRNGVHPSHFCRAADGAARKALQALEHARLVEKHPDGGRKLSSIGQRDLDRIANQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Zebrafish
Match: rps19 (ribosomal protein S19 [Source:ZFIN;Acc:ZDB-GENE-040426-1716])

HSP 1 Score: 131.339 bits (329), Expect = 1.005e-38
Identity = 67/134 (50.00%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ P+WVD+VKL++  ELAP D +W++IR AS +RHLY R   G+  +TKIY   K NG  PSH   G+  + R  L+ L  L +VE   N  R LT +G RDLDRIA Q
Sbjct:    5 VTVKDVNQQEFVRALAAFLKKSGKLKVPDWVDIVKLAKHKELAPCDENWFYIRAASTVRHLYLRGGVGVGSMTKIYGGRKRNGVCPSHFSVGSKNVARKVLQALEGLKMVEKDPNGGRRLTPQGTRDLDRIAGQ 138          
BLAST of 40S ribosomal protein S19 vs. Ensembl Zebrafish
Match: rps19 (ribosomal protein S19 [Source:ZFIN;Acc:ZDB-GENE-040426-1716])

HSP 1 Score: 131.339 bits (329), Expect = 1.005e-38
Identity = 67/134 (50.00%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ P+WVD+VKL++  ELAP D +W++IR AS +RHLY R   G+  +TKIY   K NG  PSH   G+  + R  L+ L  L +VE   N  R LT +G RDLDRIA Q
Sbjct:    5 VTVKDVNQQEFVRALAAFLKKSGKLKVPDWVDIVKLAKHKELAPCDENWFYIRAASTVRHLYLRGGVGVGSMTKIYGGRKRNGVCPSHFSVGSKNVARKVLQALEGLKMVEKDPNGGRRLTPQGTRDLDRIAGQ 138          
BLAST of 40S ribosomal protein S19 vs. Ensembl Zebrafish
Match: rps19 (ribosomal protein S19 [Source:ZFIN;Acc:ZDB-GENE-040426-1716])

HSP 1 Score: 131.339 bits (329), Expect = 1.021e-38
Identity = 67/134 (50.00%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ P+WVD+VKL++  ELAP D +W++IR AS +RHLY R   G+  +TKIY   K NG  PSH   G+  + R  L+ L  L +VE   N  R LT +G RDLDRIA Q
Sbjct:   11 VTVKDVNQQEFVRALAAFLKKSGKLKVPDWVDIVKLAKHKELAPCDENWFYIRAASTVRHLYLRGGVGVGSMTKIYGGRKRNGVCPSHFSVGSKNVARKVLQALEGLKMVEKDPNGGRRLTPQGTRDLDRIAGQ 144          
BLAST of 40S ribosomal protein S19 vs. Ensembl Zebrafish
Match: rps19 (ribosomal protein S19 [Source:ZFIN;Acc:ZDB-GENE-040426-1716])

HSP 1 Score: 130.954 bits (328), Expect = 1.473e-38
Identity = 67/134 (50.00%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ P+WVD+VKL++  ELAP D +W++IR AS +RHLY R   G+  +TKIY   K NG  PSH   G+  + R  L+ L  L +VE   N  R LT +G RDLDRIA Q
Sbjct:    5 VTVKDVNQQEFVRALAAFLKKSGKLKVPDWVDIVKLAKHKELAPCDENWFYIRAASTVRHLYLRGGVGVGSMTKIYGGRKRNGVCPSHFSVGSKNVARKVLQALEGLKMVEKDPNGGRRLTPQGTRDLDRIAGQ 138          
BLAST of 40S ribosomal protein S19 vs. Ensembl Xenopus
Match: hibadh (3-hydroxyisobutyrate dehydrogenase [Source:Xenbase;Acc:XB-GENE-950889])

HSP 1 Score: 134.035 bits (336), Expect = 1.210e-39
Identity = 67/134 (50.00%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS +RHLY R   G+  +TKIY   + NG  PSH  KG+  + R  L+ L  L +VE   N  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPCDENWFYTRAASTVRHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSKGSKSVARRVLQALENLKMVEKDPNGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Xenopus
Match: hibadh (3-hydroxyisobutyrate dehydrogenase [Source:Xenbase;Acc:XB-GENE-950889])

HSP 1 Score: 132.88 bits (333), Expect = 3.989e-39
Identity = 67/134 (50.00%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS +RHLY R   G+  +TKIY   + NG  PSH  KG+  + R  L+ L  L +VE   N  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPCDENWFYTRAASTVRHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSKGSKSVARRVLQALENLKMVEKDPNGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Xenopus
Match: hibadh (3-hydroxyisobutyrate dehydrogenase [Source:Xenbase;Acc:XB-GENE-950889])

HSP 1 Score: 132.494 bits (332), Expect = 7.124e-39
Identity = 67/134 (50.00%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS +RHLY R   G+  +TKIY   + NG  PSH  KG+  + R  L+ L  L +VE   N  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPCDENWFYTRAASTVRHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSKGSKSVARRVLQALENLKMVEKDPNGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Mouse
Match: Rps19 (ribosomal protein S19 [Source:MGI Symbol;Acc:MGI:1333780])

HSP 1 Score: 133.65 bits (335), Expect = 1.102e-39
Identity = 66/134 (49.25%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS  RHLY R   G+  +TKIY   + NG RPSH  +G+  + R  L+ L  L +VE   +  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Mouse
Match: Rps19 (ribosomal protein S19 [Source:MGI Symbol;Acc:MGI:1333780])

HSP 1 Score: 133.65 bits (335), Expect = 1.102e-39
Identity = 66/134 (49.25%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS  RHLY R   G+  +TKIY   + NG RPSH  +G+  + R  L+ L  L +VE   +  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Mouse
Match: Rps19 (ribosomal protein S19 [Source:MGI Symbol;Acc:MGI:1333780])

HSP 1 Score: 132.88 bits (333), Expect = 6.462e-39
Identity = 66/134 (49.25%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS  RHLY R   G+  +TKIY   + NG RPSH  +G+  + R  L+ L  L +VE   +  R LT +G+RDLDRIA Q
Sbjct:   40 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQ 173          
BLAST of 40S ribosomal protein S19 vs. Ensembl Mouse
Match: Rps19 (ribosomal protein S19 [Source:MGI Symbol;Acc:MGI:1333780])

HSP 1 Score: 133.65 bits (335), Expect = 7.418e-39
Identity = 66/134 (49.25%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS  RHLY R   G+  +TKIY   + NG RPSH  +G+  + R  L+ L  L +VE   +  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Mouse
Match: Rps19 (ribosomal protein S19 [Source:MGI Symbol;Acc:MGI:1333780])

HSP 1 Score: 129.028 bits (323), Expect = 5.913e-38
Identity = 63/130 (48.46%), Postives = 86/130 (66.15%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDR 534
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS  RHLY R   G+  +TKIY   + NG RPSH  +G+  + R  L+ L  L +VE   +  R LT +G+RDLDR
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDR 133          
BLAST of 40S ribosomal protein S19 vs. UniProt/SwissProt
Match: sp|Q9Y0H3|RS19_MYXGL (40S ribosomal protein S19 OS=Myxine glutinosa OX=7769 GN=rps19 PE=2 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 1.092e-40
Identity = 68/133 (51.13%), Postives = 91/133 (68.42%), Query Frame = 1
Query:  154 SVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVELS-NQKRVLTSEGRRDLDRIAFQ 546
            +VKD+ QQ++  ALA F K SGK+++P+WVD VKL +  ELAP D DWY+IR AS+ RHLY R   G+  +TKIY   + NG+RPSH  +G+  + R  L++L  L +VE   N  R LTS G+RD+DRIA Q
Sbjct:    5 TVKDVNQQEFVKALAAFFKKSGKLKKPDWVDTVKLGKHKELAPFDIDWYYIRTASVARHLYMRGGVGVGAMTKIYGGRQRNGTRPSHYSRGSRNVARKVLQSLEMLKMVEKDPNGGRRLTSIGQRDMDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. UniProt/SwissProt
Match: sp|Q8ITC3|RS19_ARGIR (40S ribosomal protein S19 OS=Argopecten irradians OX=31199 GN=RPS19 PE=2 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 3.105e-40
Identity = 70/134 (52.24%), Postives = 90/134 (67.16%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRS-TGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ISVKD+    +T ALA FLK SGK++ PEW  ++KLS+ NEL+P D DW++ R ASI RHLY RS  G+  LTKIY   K NG+ PSH  + +  + R  L+ L T  LVE  +N  R LTS+G++DLDRIA Q
Sbjct:    3 ISVKDVDSHTFTKALAAFLKKSGKMKIPEWATIIKLSKFNELSPYDEDWFYTRAASICRHLYIRSPAGVGALTKIYGDRKRNGTVPSHYCRSSGSVARRVLQALETQKLVEKDANGGRKLTSQGQKDLDRIAAQ 136          
BLAST of 40S ribosomal protein S19 vs. UniProt/SwissProt
Match: sp|Q94613|RS19_MYAAR (40S ribosomal protein S19 OS=Mya arenaria OX=6604 GN=RPS19 PE=2 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 2.189e-39
Identity = 71/134 (52.99%), Postives = 84/134 (62.69%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRS-TGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ISVKD+   ++T A A FLK SGK++ PEW D VK     EL+P + DWYFIR ASI RHLY RS  GI    KIY   +  G+ PSH  K N  I R  L++L  L +VE   N  R LTS+GRRDLDRIA Q
Sbjct:    3 ISVKDVSSHEFTRAFAAFLKKSGKMKVPEWTDFVKTGMFKELSPYEPDWYFIRAASICRHLYIRSPAGIGSFEKIYGGRRRRGTAPSHFCKANGSISRRLLQSLEGLKIVEKDPNGGRRLTSQGRRDLDRIAAQ 136          
BLAST of 40S ribosomal protein S19 vs. UniProt/SwissProt
Match: sp|P17074|RS19_RAT (40S ribosomal protein S19 OS=Rattus norvegicus OX=10116 GN=Rps19 PE=2 SV=3)

HSP 1 Score: 133.65 bits (335), Expect = 7.707e-39
Identity = 66/134 (49.25%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS  RHLY R   G+  +TKIY   + NG RPSH  +G+  + R  L+ L  L +VE   +  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. UniProt/SwissProt
Match: sp|Q9CZX8|RS19_MOUSE (40S ribosomal protein S19 OS=Mus musculus OX=10090 GN=Rps19 PE=1 SV=3)

HSP 1 Score: 133.65 bits (335), Expect = 7.707e-39
Identity = 66/134 (49.25%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ PEWVD VKL++  ELAP D +W++ R AS  RHLY R   G+  +TKIY   + NG RPSH  +G+  + R  L+ L  L +VE   +  R LT +G+RDLDRIA Q
Sbjct:    4 VTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVRPSHFSRGSKSVARRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQ 137          
BLAST of 40S ribosomal protein S19 vs. TrEMBL
Match: A0A0R3TA31 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS3918 PE=4 SV=1)

HSP 1 Score: 164.466 bits (415), Expect = 1.989e-48
Identity = 78/132 (59.09%), Postives = 95/132 (71.97%), Query Frame = 1
Query:  154 SVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVE-LSNQKRVLTSEGRRDLDRIAFQ 546
            SVKD+    Y VALA FLKNS KV+ PEWVD+VKLS ANELAP D DWYF+RCA+ILRHLY R TGI GL+K + R K  G  P H V   TGIIR CL+ L ++G+VE  ++  R ++  GRRD+D +AFQ
Sbjct:    5 SVKDVDGHVYVVALAKFLKNSNKVQPPEWVDVVKLSTANELAPSDPDWYFVRCAAILRHLYLRPTGITGLSKAFGRGKRYGVSPRHHVNAYTGIIRRCLRDLESIGIVEKRTDGGREISRSGRRDMDSVAFQ 136          
BLAST of 40S ribosomal protein S19 vs. TrEMBL
Match: A0A564ZCW8 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS14773 PE=4 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 1.507e-46
Identity = 74/132 (56.06%), Postives = 96/132 (72.73%), Query Frame = 1
Query:  154 SVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVE-LSNQKRVLTSEGRRDLDRIAFQ 546
            SVKD+    Y VALA FLKN+ K++ PEWVD+VKLS ANELAP D DW+++RCA+ILRHLY R TGI GL+K++ R+K  G  P H V   TGI+R CL+ L  LGLV+  ++  R ++  GRRD+D +AFQ
Sbjct:    5 SVKDVDGHVYVVALAKFLKNTNKIKVPEWVDVVKLSTANELAPSDPDWFYVRCAAILRHLYLRPTGITGLSKVFGRSKRYGVSPRHHVNAYTGILRRCLRELENLGLVDKRADGGREISRAGRRDMDSVAFQ 136          
BLAST of 40S ribosomal protein S19 vs. TrEMBL
Match: A0A0R3SWG9 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS10027 PE=4 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 2.529e-46
Identity = 74/132 (56.06%), Postives = 96/132 (72.73%), Query Frame = 1
Query:  154 SVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVE-LSNQKRVLTSEGRRDLDRIAFQ 546
            SVKD+    Y VALA FLKN+ K++ PEWVD+VKLS ANELAP D DW+++RCA+ILRHLY R TGI GL+K++ R+K  G  P H V   TGI+R CL+ L  LGLV+  ++  R ++  GRRD+D +AFQ
Sbjct:   22 SVKDVDGHVYVVALAKFLKNTNKIKVPEWVDVVKLSTANELAPSDPDWFYVRCAAILRHLYLRPTGITGLSKVFGRSKRYGVSPRHHVNAYTGILRRCLRELENLGLVDKRADGGREISRAGRRDMDSVAFQ 153          
BLAST of 40S ribosomal protein S19 vs. TrEMBL
Match: A0A0X3NYR9 (40S ribosomal protein S19 OS=Schistocephalus solidus OX=70667 GN=RS19 PE=4 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 1.169e-45
Identity = 71/133 (53.38%), Postives = 94/133 (70.68%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVELSNQ-KRVLTSEGRRDLDRIAFQ 546
             SVKD+    Y  ALA FLK S KV+QPEWVD+VKLS ANE AP D DW+++RCA++LRHLY R  G+ GL+K +SR KNNG RP H  + +T ++R CL  +  +GL +  +   R +TS GRRD+DRIA++
Sbjct:    4 FSVKDVDGHSYVQALAKFLKKSEKVKQPEWVDIVKLSIANEQAPYDPDWFYVRCAAVLRHLYLRPAGLAGLSKAFSRRKNNGVRPCHRARASTAVLRRCLHQVEAMGLCKKRDDGGREITSAGRRDMDRIAYE 136          
BLAST of 40S ribosomal protein S19 vs. TrEMBL
Match: A0A1S3ID66 (40S ribosomal protein S19-like OS=Lingula unguis OX=7574 GN=LOC106163135 PE=4 SV=1)

HSP 1 Score: 155.992 bits (393), Expect = 3.802e-45
Identity = 76/134 (56.72%), Postives = 96/134 (71.64%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRS-TGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            +SVKD+ Q K+T AL  FLK SGK++ PEW DLVKL+R NEL+P D DW++IRCASI RHLY R+  G+  LTK+Y   KNNG+ PSH  +G+  + R CL+ L  L +VE   N  R L+S+GRRDLDRIA Q
Sbjct:    4 VSVKDVDQHKFTKALGAFLKKSGKLKVPEWTDLVKLARFNELSPYDDDWFYIRCASIARHLYVRAPVGVGTLTKVYGARKNNGTAPSHWCRGSASVARKCLQALEGLKMVEQDQNGGRRLSSQGRRDLDRIASQ 137          
BLAST of 40S ribosomal protein S19 vs. Ensembl Cavefish
Match: rps19 (ribosomal protein S19 [Source:NCBI gene;Acc:103041478])

HSP 1 Score: 129.798 bits (325), Expect = 3.673e-38
Identity = 65/134 (48.51%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRS-TGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ P+WVD+VKL++  ELAP D +W++IR AS +RHLY RS  G+  + K+Y   K NG  PSH   G+  + R  L+ L  L ++E   N  R LT +G RDLDRIA Q
Sbjct:    6 VTVKDVNQQEFVRALAAFLKKSGKLKVPDWVDIVKLAKHKELAPCDDNWFYIRAASTIRHLYMRSGVGVGSMIKVYGGRKRNGVCPSHFSVGSKNVARKVLQALEALKMLEKDPNGGRRLTPQGTRDLDRIAGQ 139          
BLAST of 40S ribosomal protein S19 vs. Ensembl Cavefish
Match: rps19 (ribosomal protein S19 [Source:NCBI gene;Acc:103041478])

HSP 1 Score: 129.413 bits (324), Expect = 4.709e-38
Identity = 65/134 (48.51%), Postives = 89/134 (66.42%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRS-TGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ P+WVD+VKL++  ELAP D +W++IR AS +RHLY RS  G+  + K+Y   K NG  PSH   G+  + R  L+ L  L ++E   N  R LT +G RDLDRIA Q
Sbjct:    6 VTVKDVNQQEFVRALAAFLKKSGKLKVPDWVDIVKLAKHKELAPCDDNWFYIRAASTIRHLYMRSGVGVGSMIKVYGGRKRNGVCPSHFSVGSKNVARKVLQALEALKMLEKDPNGGRRLTPQGTRDLDRIAGQ 139          
BLAST of 40S ribosomal protein S19 vs. Ensembl Sea Lamprey
Match: rps19 (ribosomal protein S19 [Source:ZFIN;Acc:ZDB-GENE-040426-1716])

HSP 1 Score: 140.969 bits (354), Expect = 2.598e-43
Identity = 67/134 (50.00%), Postives = 94/134 (70.15%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVEL-SNQKRVLTSEGRRDLDRIAFQ 546
            I+VKD+ QQ++  ALA FLK SGK+++P+WVD VKL++  ELAP D DWY++R AS++RHLY R   G+  +TKIY   + NG++PSH  +G+  + R  L++L +L +VE      R LT  G+RDLDRIA Q
Sbjct:    8 ITVKDVNQQEFVKALAAFLKKSGKLKKPDWVDTVKLAKHKELAPYDGDWYYVRAASVVRHLYLRGGVGVGAMTKIYGGRQRNGTKPSHFSRGSKNVARKVLQSLESLKMVEKDPTGGRRLTPTGQRDLDRIAGQ 141          
BLAST of 40S ribosomal protein S19 vs. Ensembl Yeast
Match: RPS19B (Protein component of the small (40S) ribosomal subunit; required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19B has a paralog, RPS19A, that arose from the whole genome duplication [Source:SGD;Acc:S000005246])

HSP 1 Score: 112.079 bits (279), Expect = 3.460e-32
Identity = 57/135 (42.22%), Postives = 84/135 (62.22%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDAD-WYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVELSNQ-KRVLTSEGRRDLDRIAFQ 546
            +SV+D+  Q +  A A FL+  GK+E P +VD+VK S  NE+ PQDA+ W++ R AS+ RH+Y R   G+  L K+Y   K+ G RP   +  +  I R  L+ L  +G+VE+S +  R ++  G+RDLDRIA Q
Sbjct:    4 VSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQ 138          
BLAST of 40S ribosomal protein S19 vs. Ensembl Yeast
Match: RPS19A (Protein component of the small (40S) ribosomal subunit; required for assembly and maturation of pre-40 S particles; homologous to mammalian ribosomal protein S19, no bacterial homolog; mutations in human RPS19 are associated with Diamond Blackfan anemia; RPS19A has a paralog, RPS19B, that arose from the whole genome duplication [Source:SGD;Acc:S000005481])

HSP 1 Score: 111.694 bits (278), Expect = 3.981e-32
Identity = 57/135 (42.22%), Postives = 84/135 (62.22%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDAD-WYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVELSNQ-KRVLTSEGRRDLDRIAFQ 546
            +SV+D+  Q +  A A FL+  GK+E P +VD+VK S  NE+ PQDA+ W++ R AS+ RH+Y R   G+  L K+Y   K+ G RP   +  +  I R  L+ L  +G+VE+S +  R ++  G+RDLDRIA Q
Sbjct:    4 VSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQ 138          
BLAST of 40S ribosomal protein S19 vs. Ensembl Nematostella
Match: EDO34868 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN77])

HSP 1 Score: 135.191 bits (339), Expect = 7.253e-41
Identity = 68/134 (50.75%), Postives = 88/134 (65.67%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVE-LSNQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+   K+  ALA FLK SG ++ P+WVDLVK  +  ELAP D DWY+IR A+ILRH+Y R   G+  L KIY   KN GS PSH   G+  + R+ LK L  + LVE  S   R +TS+G+RD+DRIA Q
Sbjct:    5 VTVKDVDSHKFVKALAAFLKKSGNLKIPDWVDLVKTGKFKELAPYDPDWYYIRAAAILRHIYLRGGVGVGALRKIYGGRKNRGSAPSHFEVGSASVARSVLKGLEQIKLVEKASTGGRNITSQGQRDMDRIASQ 138          
BLAST of 40S ribosomal protein S19 vs. Ensembl Medaka
Match: rps19 (ribosomal protein S19 [Source:NCBI gene;Acc:101164091])

HSP 1 Score: 133.265 bits (334), Expect = 6.169e-39
Identity = 68/134 (50.75%), Postives = 90/134 (67.16%), Query Frame = 1
Query:  151 ISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNR-STGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVELS-NQKRVLTSEGRRDLDRIAFQ 546
            ++VKD+ QQ++  ALA FLK SGK++ P+WVDLVKL +  ELAP D +W++IR AS +RHLY R   G+  +TKIY   K NG  P+H   G+  + R  L+ L  L ++E S N  R LTS+G RDLDRIA Q
Sbjct:   49 VTVKDVNQQEFVRALAAFLKKSGKLKVPDWVDLVKLGKHKELAPSDENWFYIRAASTVRHLYLRGGAGVGSMTKIYGGRKRNGVCPAHHSVGSKNVARKVLQALELLKMIEKSPNGGRRLTSQGTRDLDRIAGQ 182          
BLAST of 40S ribosomal protein S19 vs. Planmine SMEST
Match: SMESG000009719.1 (SMESG000009719.1)

HSP 1 Score: 273.863 bits (699), Expect = 4.923e-95
Identity = 130/133 (97.74%), Postives = 132/133 (99.25%), Query Frame = 1
Query:  148 FISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVELSNQKRVLTSEGRRDLDRIAFQ 546
            FISVKDIPQQKYTVALA FLKNSGK+EQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTT+GLVELSNQKRVLTSEGRRDLDRIAFQ
Sbjct:    9 FISVKDIPQQKYTVALAGFLKNSGKIEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTIGLVELSNQKRVLTSEGRRDLDRIAFQ 141          
BLAST of 40S ribosomal protein S19 vs. Planmine SMEST
Match: SMESG000023987.1 (SMESG000023987.1)

HSP 1 Score: 273.092 bits (697), Expect = 9.929e-95
Identity = 129/133 (96.99%), Postives = 132/133 (99.25%), Query Frame = 1
Query:  148 FISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVELSNQKRVLTSEGRRDLDRIAFQ 546
            FISVKDIPQQKYTVALA FLKNSGK+EQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHM+KGNTGIIRNCLKTLTT+GLVELSNQKRVLTSEGRRDLDRIAFQ
Sbjct:    9 FISVKDIPQQKYTVALAGFLKNSGKIEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMIKGNTGIIRNCLKTLTTIGLVELSNQKRVLTSEGRRDLDRIAFQ 141          
BLAST of 40S ribosomal protein S19 vs. Planmine SMEST
Match: SMESG000023987.1 (SMESG000023987.1)

HSP 1 Score: 273.478 bits (698), Expect = 1.740e-94
Identity = 129/133 (96.99%), Postives = 132/133 (99.25%), Query Frame = 1
Query:  148 FISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKGNTGIIRNCLKTLTTLGLVELSNQKRVLTSEGRRDLDRIAFQ 546
            FISVKDIPQQKYTVALA FLKNSGK+EQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHM+KGNTGIIRNCLKTLTT+GLVELSNQKRVLTSEGRRDLDRIAFQ
Sbjct:   37 FISVKDIPQQKYTVALAGFLKNSGKIEQPEWVDLVKLSRANELAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMIKGNTGIIRNCLKTLTTIGLVELSNQKRVLTSEGRRDLDRIAFQ 169          
The following BLAST results are available for this feature:
BLAST of 40S ribosomal protein S19 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RPS191.485e-3848.51ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC... [more]
RPS191.485e-3848.51ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC... [more]
RPS191.485e-3848.51ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC... [more]
RPS191.367e-1736.46ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC... [more]
RPS195.914e-1554.72ribosomal protein S19 [Source:HGNC Symbol;Acc:HGNC... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rps-191.025e-3445.0440S ribosomal protein S19 [Source:UniProtKB/Swiss... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RpS19a6.856e-3849.25gene:FBgn0010412 transcript:FBtr0340149[more]
RpS19a6.856e-3849.25gene:FBgn0010412 transcript:FBtr0345129[more]
RpS19a6.856e-3849.25gene:FBgn0010412 transcript:FBtr0074311[more]
RpS19a6.856e-3849.25gene:FBgn0010412 transcript:FBtr0074312[more]
RpS19a6.856e-3849.25gene:FBgn0010412 transcript:FBtr0074313[more]
back to top
BLAST of 40S ribosomal protein S19 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
rps191.005e-3850.00ribosomal protein S19 [Source:ZFIN;Acc:ZDB-GENE-04... [more]
rps191.005e-3850.00ribosomal protein S19 [Source:ZFIN;Acc:ZDB-GENE-04... [more]
rps191.021e-3850.00ribosomal protein S19 [Source:ZFIN;Acc:ZDB-GENE-04... [more]
rps191.473e-3850.00ribosomal protein S19 [Source:ZFIN;Acc:ZDB-GENE-04... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
hibadh1.210e-3950.003-hydroxyisobutyrate dehydrogenase [Source:Xenbase... [more]
hibadh3.989e-3950.003-hydroxyisobutyrate dehydrogenase [Source:Xenbase... [more]
hibadh7.124e-3950.003-hydroxyisobutyrate dehydrogenase [Source:Xenbase... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Rps191.102e-3949.25ribosomal protein S19 [Source:MGI Symbol;Acc:MGI:1... [more]
Rps191.102e-3949.25ribosomal protein S19 [Source:MGI Symbol;Acc:MGI:1... [more]
Rps196.462e-3949.25ribosomal protein S19 [Source:MGI Symbol;Acc:MGI:1... [more]
Rps197.418e-3949.25ribosomal protein S19 [Source:MGI Symbol;Acc:MGI:1... [more]
Rps195.913e-3848.46ribosomal protein S19 [Source:MGI Symbol;Acc:MGI:1... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9Y0H3|RS19_MYXGL1.092e-4051.1340S ribosomal protein S19 OS=Myxine glutinosa OX=7... [more]
sp|Q8ITC3|RS19_ARGIR3.105e-4052.2440S ribosomal protein S19 OS=Argopecten irradians ... [more]
sp|Q94613|RS19_MYAAR2.189e-3952.9940S ribosomal protein S19 OS=Mya arenaria OX=6604 ... [more]
sp|P17074|RS19_RAT7.707e-3949.2540S ribosomal protein S19 OS=Rattus norvegicus OX=... [more]
sp|Q9CZX8|RS19_MOUSE7.707e-3949.2540S ribosomal protein S19 OS=Mus musculus OX=10090... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0R3TA311.989e-4859.09Uncharacterized protein OS=Rodentolepis nana OX=10... [more]
A0A564ZCW81.507e-4656.06Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A0R3SWG92.529e-4656.06Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A0X3NYR91.169e-4553.3840S ribosomal protein S19 OS=Schistocephalus solid... [more]
A0A1S3ID663.802e-4556.7240S ribosomal protein S19-like OS=Lingula unguis O... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rps193.673e-3848.51ribosomal protein S19 [Source:NCBI gene;Acc:103041... [more]
rps194.709e-3848.51ribosomal protein S19 [Source:NCBI gene;Acc:103041... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rps192.598e-4350.00ribosomal protein S19 [Source:ZFIN;Acc:ZDB-GENE-04... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
RPS19B3.460e-3242.22Protein component of the small (40S) ribosomal sub... [more]
RPS19A3.981e-3242.22Protein component of the small (40S) ribosomal sub... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO348687.253e-4150.75Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
rps196.169e-3950.75ribosomal protein S19 [Source:NCBI gene;Acc:101164... [more]
back to top
BLAST of 40S ribosomal protein S19 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000009719.14.923e-9597.74SMESG000009719.1[more]
SMESG000023987.19.929e-9596.99SMESG000023987.1[more]
SMESG000023987.11.740e-9496.99SMESG000023987.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026696 ID=SMED30026696|Name=40S ribosomal protein S19|organism=Schmidtea mediterranea sexual|type=transcript|length=616bp
AAAAATTCGTTTTGTAAAATTAATTTTAAAATTTAGATAGTTTTTAAACA
TTTAAGAAAATTATTATCTGAATACAAAAATTTGTTTAAATTACAAAACT
TACTATTATAATAAAAATTCAAAATGGTTAAGACTAAAAAAGGTTTATTT
ATTAGTGTTAAAGATATTCCTCAACAAAAGTATACTGTTGCTTTAGCTGA
TTTTTTGAAAAATTCTGGTAAAGTTGAACAACCAGAATGGGTAGATTTAG
TGAAATTGTCCAGAGCCAATGAATTAGCACCGCAAGATGCTGATTGGTAT
TTTATAAGATGTGCCAGTATTCTTCGTCATTTGTACAACAGATCCACTGG
TATCAACGGTTTGACTAAGATTTACAGCCGAAACAAAAATAATGGCAGCA
GACCTTCCCATATGGTTAAAGGAAACACTGGTATTATTCGAAATTGCTTG
AAAACCTTGACCACATTGGGATTAGTTGAGCTCTCAAATCAAAAAAGAGT
CTTGACTAGTGAAGGAAGAAGGGATTTGGACAGAATCGCTTTTCAATTGA
AGAATAAAGAAAAATTATAATTCTTTAATAAATTTTTGGATTATTTAAAA
AAAAAGATCGGAAGAG
back to top

protein sequence of SMED30026696-orf-1

>SMED30026696-orf-1 ID=SMED30026696-orf-1|Name=SMED30026696-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=149bp
MVKTKKGLFISVKDIPQQKYTVALADFLKNSGKVEQPEWVDLVKLSRANE
LAPQDADWYFIRCASILRHLYNRSTGINGLTKIYSRNKNNGSRPSHMVKG
NTGIIRNCLKTLTTLGLVELSNQKRVLTSEGRRDLDRIAFQLKNKEKL*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000120progenitor cell
PLANA:0000429neoblast
PLANA:0002032epidermal cell
PLANA:0002109X1 cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR038111Ribosomal_S19e_sf
IPR036390WH_DNA-bd_sf
IPR001266Ribosomal_S19e
IPR011991WHTH_DNA-bd_dom
Vocabulary: molecular function
TermDefinition
GO:0003735structural constituent of ribosome
Vocabulary: cellular component
TermDefinition
GO:0005840ribosome
Vocabulary: biological process
TermDefinition
GO:0006412translation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001266Ribosomal protein S19eSMARTSM01413Ribosomal_S19e_2coord: 11..145
e-value: 1.3E-63
score: 227.3
IPR001266Ribosomal protein S19ePFAMPF01090Ribosomal_S19ecoord: 11..143
e-value: 1.7E-47
score: 160.5
IPR001266Ribosomal protein S19ePANTHERPTHR1171040S RIBOSOMAL PROTEIN S19coord: 9..142
IPR038111Ribosomal protein S19e domain superfamilyGENE3DG3DSA:1.10.10.2700coord: 4..148
e-value: 2.2E-50
score: 172.2
NoneNo IPR availablePANTHERPTHR11710:SF040S RIBOSOMAL PROTEIN S19coord: 9..142
NoneNo IPR availablePRODOMPD003854coord: 11..121
e-value: 5.0E-29
score: 314.0
IPR036390Winged helix DNA-binding domain superfamilySUPERFAMILYSSF46785"Winged helix" DNA-binding domaincoord: 10..145