MATH domain-containing protein

Overview
NameMATH domain-containing protein
Smed IDSMED30026637
Length (bp)1865
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of MATH domain-containing protein (SMED30026637) t-SNE clustered cells

Violin plots show distribution of expression levels for MATH domain-containing protein (SMED30026637) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of MATH domain-containing protein (SMED30026637) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for MATH domain-containing protein (SMED30026637) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Homology
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 62.3882 bits (150), Expect = 1.309e-9
Identity = 45/172 (26.16%), Postives = 79/172 (45.93%), Query Frame = 3 
Query:  396 VKDVEVFPIELQRTAVISEIY-GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            V D+ +  ++L+   + +  Y G + W++   K +   A       ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q +         K + NS +   +++PT E N  S          VL N    ++D I+IK +++
Sbjct:  311 VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSS---FKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVD 478
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 62.003 bits (149), Expect = 1.898e-9
Identity = 45/172 (26.16%), Postives = 79/172 (45.93%), Query Frame = 3 
Query:  396 VKDVEVFPIELQRTAVISEIY-GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            V D+ +  ++L+   + +  Y G + W++   K +   A       ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q +         K + NS +   +++PT E N  S          VL N    ++D I+IK +++
Sbjct:  369 VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSS---FKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVD 536
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 62.003 bits (149), Expect = 1.898e-9
Identity = 45/172 (26.16%), Postives = 79/172 (45.93%), Query Frame = 3 
Query:  396 VKDVEVFPIELQRTAVISEIY-GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            V D+ +  ++L+   + +  Y G + W++   K +   A       ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q +         K + NS +   +++PT E N  S          VL N    ++D I+IK +++
Sbjct:  369 VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSS---FKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVD 536
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 62.003 bits (149), Expect = 2.441e-9
Identity = 45/172 (26.16%), Postives = 79/172 (45.93%), Query Frame = 3 
Query:  396 VKDVEVFPIELQRTAVISEIY-GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            V D+ +  ++L+   + +  Y G + W++   K +   A       ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q +         K + NS +   +++PT E N  S          VL N    ++D I+IK +++
Sbjct:  394 VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSS---FKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVD 561
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Human
Match: TRAF3 (TNF receptor associated factor 3 [Source:HGNC Symbol;Acc:HGNC:12033])

HSP 1 Score: 62.003 bits (149), Expect = 2.441e-9
Identity = 45/172 (26.16%), Postives = 79/172 (45.93%), Query Frame = 3 
Query:  396 VKDVEVFPIELQRTAVISEIY-GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            V D+ +  ++L+   + +  Y G + W++   K +   A       ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q +         K + NS +   +++PT E N  S          VL N    ++D I+IK +++
Sbjct:  394 VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSS---FKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVD 561
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80])

HSP 1 Score: 70.8626 bits (172), Expect = 1.130e-12
Identity = 46/162 (28.40%), Postives = 82/162 (50.62%), Query Frame = 3 
Query:  426 LQRTAVISEIYG-QIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAAC-FG-GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWE----RPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIK 890
            L      +E++G Q+ W++ K++++ N AK    + IFS PF SH+ GYK+   AC FG G   G  + +   L+  E++  L WPF   ++  L++Q N     +  + +  + R +   E    RP  E+N      +  +L  +L N    ++DKI+++
Sbjct:  251 LSAAETCTEMFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQ-NPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCSLA-ILQN--YVKDDKIYVQ 408
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586])

HSP 1 Score: 56.9954 bits (136), Expect = 1.801e-8
Identity = 42/139 (30.22%), Postives = 66/139 (47.48%), Query Frame = 3 
Query:  486 VKEKMNNAKKSMKSEIFSAPFYSHKNGYK-LCLAACFG-GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNET---SNMYALTNLIDVLNNDDLYQNDKIWI 887
            VK   N + +S    I+S PFYSH  GYK + +AA +G GL       V   LM  E++D L WPF  +V F +++   + +   KT+  N      +  ERP   +N T    N   L  + +   + D++   K+ +
Sbjct:  172 VKATKNKSHRS----IYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILSDDKKELLT-KTIYVNEMPEIQEFLERPEGLRNGTFGFQNFLPLAKVTEFAADGDIFIQIKVLL 305
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345])

HSP 1 Score: 64.6994 bits (156), Expect = 1.664e-10
Identity = 43/151 (28.48%), Postives = 68/151 (45.03%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQIN-ETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            G   W++ +   +  +A       +FS  FYS K GYK+CL       G  RG+ L + F +M  +Y+  L WPF   V   L++Q N E +        +S S     ++RP SE N  S       L  +       ++D I+IK +++
Sbjct:  383 GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRPDVSSTS-----FQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 528
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345])

HSP 1 Score: 64.6994 bits (156), Expect = 1.664e-10
Identity = 43/151 (28.48%), Postives = 68/151 (45.03%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQIN-ETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            G   W++ +   +  +A       +FS  FYS K GYK+CL       G  RG+ L + F +M  +Y+  L WPF   V   L++Q N E +        +S S     ++RP SE N  S       L  +       ++D I+IK +++
Sbjct:  383 GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRPDVSSTS-----FQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 528
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345])

HSP 1 Score: 64.6994 bits (156), Expect = 1.745e-10
Identity = 43/151 (28.48%), Postives = 68/151 (45.03%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQIN-ETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            G   W++ +   +  +A       +FS  FYS K GYK+CL       G  RG+ L + F +M  +Y+  L WPF   V   L++Q N E +        +S S     ++RP SE N  S       L  +       ++D I+IK +++
Sbjct:  396 GVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRPDVSSTS-----FQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 541
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Zebrafish
Match: unm_sa808 (un-named sa808 [Source:ZFIN;Acc:ZDB-GENE-120727-21])

HSP 1 Score: 62.7734 bits (151), Expect = 2.483e-10
Identity = 51/209 (24.40%), Postives = 93/209 (44.50%), Query Frame = 3 
Query:  288 NTFDAKADKYSMKVFELKSAEESVKTMEKDNTVNILVKDVEVFPIELQRTAVISEIYGQIF-WEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQIN-ETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
             T +A   ++ +   ++++    V+ +E+     + VKD+ V  +E +   + +  +  +F W +    +K  +A       +FS  FY+ K GYK+CL       G  RG  L + F +M    +  L WPF   V   L++Q N E +         S+S     ++RP SE N  S       L  +   +   ++D I+IK +++
Sbjct:   78 TTMEASNRQHRLDQDKIEALSNKVRQLER----QVGVKDLTVAEMEGRLREMSATTFDGVFIWRISDFTKKRQDAIAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGMSDALLKWPFNQKVTLMLLDQSNREHIIDAFRPDITSSS-----FQRPVSEMNIASGCPLFCPLAKLEGKNSYIRDDTIFIKAIVD 277
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Zebrafish
Match: traf5 (Tnf receptor-associated factor 5 [Source:ZFIN;Acc:ZDB-GENE-071120-3])

HSP 1 Score: 62.003 bits (149), Expect = 4.035e-10
Identity = 52/205 (25.37%), Postives = 97/205 (47.32%), Query Frame = 3 
Query:  300 AKADKYSMKVFELKSAEESVKTMEKDNTVNILVKDVEVFPIEL--QRTAVI--SEIYGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLN--NDDLYQNDKIWIK 890
            A  D    +V   +S  E +  +E+    +  + D+ V  ++   QR   +  S   G++ W   KV++  +  +K   + + S+PFY+ ++GYKL + A  G  G  RG+ + +  T+M  +++  L WPF  N+   L++Q         T   + NS   D + RPTS+ N  +      +  D+ N  N    +++ ++IK
Sbjct:   54 ASLDSLRQQVAVTESLREHLGALEQTCERHTRLLDIHVEQLQCNEQRLRQLESSSYDGKLIW---KVRDYWH--RKESGAALSSSPFYTSRSGYKLSVRAYLGGDGSGRGSHMSLYITIMRGDFDSFLPWPFRQNITLTLLDQSGTRNHMSHTFIPDVNS---DSFHRPTSDANVATGFTRFISHCDLENPRNAVFVRDETLFIK 250
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Xenopus
Match: sytl2 (synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-945155])

HSP 1 Score: 65.4698 bits (158), Expect = 1.419e-10
Identity = 42/131 (32.06%), Postives = 70/131 (53.44%), Query Frame = 3 
Query:  423 ELQRTAVISEIYGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACF--GGLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKK--TVKFNSNSRNVDKWERPTSEKN 803
            +++  +V SE  G + W++     K+  AK     E FS PFY+HK GYKL ++A     G   G+ L V   ++  EY++ L WPF + V F L++Q + ++   +  T  FN +  N   +++PT  +N
Sbjct:  298 QVEELSVSSE--GVLIWKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQSDPSLSKPQHITETFNPDP-NWKNFQKPTGSRN 425
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 61.6178 bits (148), Expect = 2.793e-9
Identity = 45/172 (26.16%), Postives = 78/172 (45.35%), Query Frame = 3 
Query:  396 VKDVEVFPIELQRTAVISEIY-GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            V D+ +  ++L+   + +  Y G + W++   K +   A       ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q           K + NS +   +++PT E N  S          VL N    ++D I+IK +++
Sbjct:  362 VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSS---FKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVD 529
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 61.2326 bits (147), Expect = 3.785e-9
Identity = 45/172 (26.16%), Postives = 78/172 (45.35%), Query Frame = 3 
Query:  396 VKDVEVFPIELQRTAVISEIY-GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            V D+ +  ++L+   + +  Y G + W++   K +   A       ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q           K + NS +   +++PT E N  S          VL N    ++D I+IK +++
Sbjct:  387 VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSS---FKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVD 554
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Xenopus
Match: hspb6 (heat shock protein family B (small) member 6 [Source:Xenbase;Acc:XB-GENE-876273])

HSP 1 Score: 56.6102 bits (135), Expect = 6.393e-8
Identity = 40/148 (27.03%), Postives = 71/148 (47.97%), Query Frame = 3 
Query:  384 VNILVKDVEVFPIELQRTAVISEIYGQIF-WEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQIN-ETVFAKKTVKFNSNSRNVDKWERPTSEKNETSN 815
              + +KD+ +  +E++   +    Y  +F W++  +  K ++A       ++S  FY+ K GYK+CL       G  +G  + + FT+M  EY+  L WPF   V F L++  N ++VF        S S     ++RP ++ N  S 
Sbjct:  204 CTLAMKDIVLNELEMRSACLEQTSYDGVFLWKISDLTNKSHDAVTGRAISLYSPAFYTAKYGYKVCLRIYLNGDGAGKGTHVSLFFTVMKGEYDALLPWPFKHKVTFVLVDHNNRDSVFDAFRPDVTSAS-----FQRPINDMNVASG 346
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925])

HSP 1 Score: 56.225 bits (134), Expect = 1.249e-7
Identity = 41/152 (26.97%), Postives = 71/152 (46.71%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLN--NDDLYQNDKIWIKGVLE 902
            G++ W++   + K   A +     IFS  FY+   GY+LC  A     G  +G+ L + F +M  E++  L WPF   V   L++Q  +        + + NS +   ++RP SE N  S      +   + N  N    ++D ++IK V++
Sbjct:  333 GKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRADPNSSS---FKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIKIVVD 481
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548])

HSP 1 Score: 65.855 bits (159), Expect = 1.529e-11
Identity = 41/147 (27.89%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLY-QNDKIWIK 890
            G++ W+V   + K   A +     +FS PFY+ + GY+LC  A     G  +G  L + F +M  E++  L WPF   V   L++Q  +     +T K + NS +   ++RP  E N  S      +   + N+ + Y ++D +++K
Sbjct:   96 GKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSS---FKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLK 239
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548])

HSP 1 Score: 65.855 bits (159), Expect = 1.529e-11
Identity = 41/147 (27.89%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLY-QNDKIWIK 890
            G++ W+V   + K   A +     +FS PFY+ + GY+LC  A     G  +G  L + F +M  E++  L WPF   V   L++Q  +     +T K + NS +   ++RP  E N  S      +   + N+ + Y ++D +++K
Sbjct:   96 GKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSS---FKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLK 239
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548])

HSP 1 Score: 64.3142 bits (155), Expect = 2.492e-10
Identity = 41/147 (27.89%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLY-QNDKIWIK 890
            G++ W+V   + K   A +     +FS PFY+ + GY+LC  A     G  +G  L + F +M  E++  L WPF   V   L++Q  +     +T K + NS +   ++RP  E N  S      +   + N+ + Y ++D +++K
Sbjct:  398 GKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSS---FKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLK 541
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548])

HSP 1 Score: 64.3142 bits (155), Expect = 2.492e-10
Identity = 41/147 (27.89%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLY-QNDKIWIK 890
            G++ W+V   + K   A +     +FS PFY+ + GY+LC  A     G  +G  L + F +M  E++  L WPF   V   L++Q  +     +T K + NS +   ++RP  E N  S      +   + N+ + Y ++D +++K
Sbjct:  398 GKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSS---FKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLK 541
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Mouse
Match: Traf3 (TNF receptor-associated factor 3 [Source:MGI Symbol;Acc:MGI:108041])

HSP 1 Score: 62.003 bits (149), Expect = 1.482e-9
Identity = 45/172 (26.16%), Postives = 79/172 (45.93%), Query Frame = 3 
Query:  396 VKDVEVFPIELQRTAVISEIY-GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            V D+ +  ++L+   + +  Y G + W++   K +   A       ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q +         K + NS +   +++PT E N  S          VL N    ++D I+IK +++
Sbjct:  368 VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSS---FKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVD 535
[Close]
BLAST of MATH domain-containing protein vs. UniProt/SwissProt
Match: sp|P70191|TRAF5_MOUSE (TNF receptor-associated factor 5 OS=Mus musculus OX=10090 GN=Traf5 PE=1 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 1.627e-9
Identity = 41/147 (27.89%), Postives = 72/147 (48.98%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLY-QNDKIWIK 890
            G++ W+V   + K   A +     +FS PFY+ + GY+LC  A     G  +G  L + F +M  E++  L WPF   V   L++Q  +     +T K + NS +   ++RP  E N  S      +   + N+ + Y ++D +++K
Sbjct:  404 GKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSS---FKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLK 547
[Close]
BLAST of MATH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q13114|TRAF3_HUMAN (TNF receptor-associated factor 3 OS=Homo sapiens OX=9606 GN=TRAF3 PE=1 SV=2)

HSP 1 Score: 62.003 bits (149), Expect = 1.172e-8
Identity = 45/172 (26.16%), Postives = 79/172 (45.93%), Query Frame = 3 
Query:  396 VKDVEVFPIELQRTAVISEIY-GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            V D+ +  ++L+   + +  Y G + W++   K +   A       ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q +         K + NS +   +++PT E N  S          VL N    ++D I+IK +++
Sbjct:  394 VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSS---FKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVD 561
[Close]
BLAST of MATH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q60803|TRAF3_MOUSE (TNF receptor-associated factor 3 OS=Mus musculus OX=10090 GN=Traf3 PE=1 SV=2)

HSP 1 Score: 61.6178 bits (148), Expect = 1.333e-8
Identity = 45/172 (26.16%), Postives = 79/172 (45.93%), Query Frame = 3 
Query:  396 VKDVEVFPIELQRTAVISEIY-GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            V D+ +  ++L+   + +  Y G + W++   K +   A       ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q +         K + NS +   +++PT E N  S          VL N    ++D I+IK +++
Sbjct:  393 VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSS---FKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVD 560
[Close]
BLAST of MATH domain-containing protein vs. UniProt/SwissProt
Match: sp|O00463|TRAF5_HUMAN (TNF receptor-associated factor 5 OS=Homo sapiens OX=9606 GN=TRAF5 PE=1 SV=2)

HSP 1 Score: 57.7658 bits (138), Expect = 1.898e-7
Identity = 39/122 (31.97%), Postives = 58/122 (47.54%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNM 818
            G++ W+V   K K   A       IFS  FY+ + GY+LC  A     G  RG+ L + F +M  E++  L WPF   V   L++Q  +     +T K + NS +   ++RP  E N  S  
Sbjct:  404 GKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIM-ETFKPDPNSSS---FKRPDGEMNIASGC 521
[Close]
BLAST of MATH domain-containing protein vs. UniProt/SwissProt
Match: sp|Q13077|TRAF1_HUMAN (TNF receptor-associated factor 1 OS=Homo sapiens OX=9606 GN=TRAF1 PE=1 SV=1)

HSP 1 Score: 56.225 bits (134), Expect = 5.768e-7
Identity = 43/152 (28.29%), Postives = 67/152 (44.08%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGGLMRG--NCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQIN-ETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLY-QNDKIWIKGVLE 902
            G   W++  V  + + +       +FS  FY+ K GYKLCL     G   G    L +   +M  EY+  L WPF   V F L++Q N E          +S S     ++RP SE N  S       L  + +    Y ++D +++K ++E
Sbjct:  267 GTFLWKITNVTRRCHESACGRTVSLFSPAFYTAKYGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAIDAFRPDLSSAS-----FQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVE 413
[Close]
BLAST of MATH domain-containing protein vs. TrEMBL
Match: A0A564YXW8 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS10639 PE=4 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 1.561e-13
Identity = 47/135 (34.81%), Postives = 74/135 (54.81%), Query Frame = 3 
Query:  420 IELQRTAVISEIYGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGG--LMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQ-INETVFAKK--TVKFNSNSRNVDKWERPTSEKNET 809
            ++LQR     E      W +   KEK + A++  K+ +FS+PFYSH++GY++CL+ C  G    RG  L V   +   EY+  LSWPF F +  +L++Q IN  +      T++ N    N    +RP+SE+N+ 
Sbjct:  318 MKLQRCEAFFE--PSFIWRIDGYKEKFDEAQQGRKTTLFSSPFYSHRHGYRVCLSICPNGEQRFRGKYLSVFLCICRGEYDALLSWPFSFPITLKLLDQNINPDLRQDHQVTIRPNPIPSNNAYLKRPSSERNQC 450
[Close]
BLAST of MATH domain-containing protein vs. TrEMBL
Match: A0A158RA51 (Uncharacterized protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS8464 PE=4 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 1.806e-13
Identity = 50/166 (30.12%), Postives = 86/166 (51.81%), Query Frame = 3 
Query:  420 IELQRTAVISEIYGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGG--LMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKK---TVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            ++LQR     E      W++   +EK   A++  K+ +FS PFYSH++GY++CL+ C  G    RG  L V   +   EY+  LSWPF + +  +L++Q  +    +    T++ N    N    +RP+SE+N+         L D L++ D   ++ I+IK + +
Sbjct:  325 MKLQRCETYFE--PSFVWKIDGYREKFEEAQQGRKTSLFSNPFYSHRHGYRVCLSICPNGEQRHRGKYLSVFVCICRGEYDALLSWPFSYPITLKLLDQNIDPGLRQDHVVTIRPNPIPSNNAYLKRPSSERNQCFGSPRFLEL-DQLHSHDFVVDNTIFIKAIFD 487
[Close]
BLAST of MATH domain-containing protein vs. TrEMBL
Match: A0A068Y4Q1 (TNF receptor associated factor 3 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000548900 PE=4 SV=1)

HSP 1 Score: 83.9593 bits (206), Expect = 2.410e-13
Identity = 49/166 (29.52%), Postives = 86/166 (51.81%), Query Frame = 3 
Query:  420 IELQRTAVISEIYGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGG--LMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKK---TVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            ++LQR     E      W++   +EK   A++  K+ +FS PFYSH++GY++CL+ C  G    RG  L V   +   EY+  LSWPF + +  +L++Q  +    +    T++ N    N    +RP+SE+N+         L D L++ D   ++ ++IK + +
Sbjct:  310 MKLQRCEAYFE--PSFVWKIDGYREKFEEAQQGRKTSLFSNPFYSHRHGYRVCLSICPNGEQRYRGRYLSVFICICRGEYDALLSWPFSYPITLKLLDQNIDPGMRQDHVVTIRPNPIPSNNAYLKRPSSERNQCFGSPRFLEL-DQLHSRDFVVDNTLYIKAIFD 472
[Close]
BLAST of MATH domain-containing protein vs. TrEMBL
Match: A0A1S3KE24 (TNF receptor-associated factor 4 OS=Lingula unguis OX=7574 GN=LOC106181010 PE=4 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 5.183e-13
Identity = 52/160 (32.50%), Postives = 84/160 (52.50%), Query Frame = 3 
Query:  429 QRTAVISEIYG-QIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAAC-FG-GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKK---TVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIK 890
            +R   + ++YG Q  W++   +EK++ AK   K  IFS PF + +NGYK+ L+AC FG G  RG  + +   +   E +  LSWPF   V F L++Q  +    +    TVK N+   N     RP+ ++N +        L +V++  D  ++D I+IK
Sbjct:  293 KRIEGLEKLYGAQFVWKIDSYQEKLDEAKAGTKRTIFSQPFLTSRNGYKMALSACLFGDGKARGKFMSLFACICKGESDALLSWPFSHRVTFTLMDQCEDPAARRNVTYTVKPNTCKDNKPFLGRPSGDRNASFGAQKFVEL-EVMSTLDYIRDDTIFIK 451
[Close]
BLAST of MATH domain-containing protein vs. TrEMBL
Match: A0A5K3EX78 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 5.333e-13
Identity = 48/149 (32.21%), Postives = 80/149 (53.69%), Query Frame = 3 
Query:  471 WEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGG--LMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKK---TVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            W +   +EK+  A++  K+ +FS+PFYSH++GY++CL+ C  G    RG  L V   L   EY+  LSWPF   +  +L++Q  +    K    T++ N  + N    +RPT+E+N+         L D LN+ +   ++ I+IK   +
Sbjct:  307 WRIDGYREKVEEAQQGRKTTLFSSPFYSHRHGYRVCLSLCPYGEQRYRGKYLSVFVCLCRGEYDALLSWPFSCPITLKLLDQTIDPTSRKDHVVTIRPNPVASNNAYLKRPTNERNQYFGSPRFIEL-DQLNSSNYIIDNTIFIKAYFD 454
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252])

HSP 1 Score: 66.2402 bits (160), Expect = 4.961e-11
Identity = 58/213 (27.23%), Postives = 100/213 (46.95%), Query Frame = 3 
Query:  333 ELKSAEESVKTMEKDNTVNI-LVKDVEVFPIELQRTAV-----ISEIY------------GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAA-CFG-GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELI--NQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLY-QNDKIWIKGVLE 902
            E++  + +V  +E+DN  N+ L++ +E    E Q+  +     IS +             G   W +  V +K+  A    KS  +S  FY+ + G+K+C+    +G G+ +G  + + F +M  +Y+  LSWPF   V F LI  NQ    V A     F  + R+   ++RP SE N  S       L  + +    Y ++D ++IK V++
Sbjct:  309 EVEKTQLTVVVLERDNHNNMNLIQHLEAVVAEQQQRLIRKDLQISSLQQSISAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQREHVVDA-----FRPDLRSA-SFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVVD 515
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Cavefish
Match: traf1 (TNF receptor-associated factor 1-like [Source:NCBI gene;Acc:103045252])

HSP 1 Score: 65.855 bits (159), Expect = 5.998e-11
Identity = 56/213 (26.29%), Postives = 99/213 (46.48%), Query Frame = 3 
Query:  333 ELKSAEESVKTMEKDNTVNI-LVKDVEVFPIELQRTAVISEIY-----------------GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAA-CFG-GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELI--NQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLY-QNDKIWIKGVLE 902
            E++  + +V  +E+DN  N+ L++ +E    E Q+  +  ++                  G   W +  V +K+  A    KS  +S  FY+ + G+K+C+    +G G+ +G  + + F +M  +Y+  LSWPF   V F LI  NQ    V A     F  + R+   ++RP SE N  S       L  + +    Y ++D ++IK V++
Sbjct:  332 EVEKTQLTVVVLERDNHNNMNLIQHLEAVVAEQQQRLIRKDLQISSLQQSISAQQDVSYDGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQREHVVDA-----FRPDLRSA-SFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVVD 538
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000035169.1 (pep primary_assembly:Astyanax_mexicanus-2.0:9:3354744:3362219:1 gene:ENSAMXG00000029095.1 transcript:ENSAMXT00000035169.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 1.704e-10
Identity = 44/146 (30.14%), Postives = 65/146 (44.52%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIK 890
            G + W++   K +   A  S    ++S PFY+   GYK+C        G+ +G  L + F +M  EY+  L WPF   V   L++Q           K + NS +   + RPT E N  S    L     VL N    ++D I+IK
Sbjct:    4 GTLIWKIRDYKRRKAEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPNSSS---FRRPTGEMNIASGC-PLFVAQTVLENGTYIKDDTIFIK 145
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261])

HSP 1 Score: 64.3142 bits (155), Expect = 2.156e-10
Identity = 43/151 (28.48%), Postives = 67/151 (44.37%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQIN-ETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            G   W++     +  +A       +FS  FYS K GYK+CL       G  RG+ L + F +M  +Y+  L WPF   V   L++Q N E +        +S S     ++RP SE N  S       L  +       ++D I+IK +++
Sbjct:  382 GVFVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRPDISSTS-----FQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVD 527
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Cavefish
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:103024022])

HSP 1 Score: 63.929 bits (154), Expect = 2.634e-10
Identity = 42/157 (26.75%), Postives = 81/157 (51.59%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACF--GGLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKK--TVKFNSNSRNVDKWERPTSEKN---ETSNMYALTNLI--DVLNNDDLYQNDKIWIKGVLE 902
            G + W++     K+  AK     E FS PFY+H+ GYKL ++A     G   G+ L +   ++  EY++ L WPF + V F +++Q + ++   +  T  FN +  N   +++P+S +N   E++  +     I  D +   +  +++ I++K  +E
Sbjct:  308 GVLIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQSDPSLSKPQHITETFNPDP-NWKNFQKPSSSRNSLDESTLGFGYPKFISHDEIRKRNYIRDNAIFLKASIE 463
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 65.4698 bits (158), Expect = 1.462e-11
Identity = 42/150 (28.00%), Postives = 69/150 (46.00%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            G++ W++     +  +A       ++S PFY+   GY++C  A     G+ RG  L + F +M  EY+  L WPF   V   L++Q         T K +  S     + RPTS+ N  S      + +  L +    Q+D I+IK V++
Sbjct:  325 GKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPDPAS---SSFRRPTSDMNIASGCPLFVSHV-ALESASYLQDDTIFIKVVVD 470
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 57.3806 bits (137), Expect = 4.556e-9
Identity = 44/188 (23.40%), Postives = 78/188 (41.49%), Query Frame = 3 
Query:  345 AEESVKTMEKDNTVNILVKDVEVFPIELQRTAVISEIYGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
             EE     E+  T++  + D     +++  TA  S   G++ W++     +   A       ++S PFY+   GYK+C  A     G+ RG  L + F +M  EY+  L WPF   V   L++Q         T   +  S     + RP  + N  S      + +  L       +D ++++ V++
Sbjct:  233 CEERCHMHEQRLTMHDGLLDTAERRLQVLETAGYS---GKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPDPAS---GSFRRPDGDMNVASGCPLFVSHV-ALEGSSYLVDDTVFVRVVVD 413
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Nematostella
Match: EDO35237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM27])

HSP 1 Score: 66.2402 bits (160), Expect = 1.665e-11
Identity = 39/113 (34.51%), Postives = 57/113 (50.44%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLC--LAACFGGLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQ-----INETVFAKK-TVKFNSNSRNVD 773
            G   W++ K  E+   AK    + I+S+PFY+H+ GYKLC  L     G  R N L +   LM  EY+  L WPF   +   LI+Q     I+ET      ++ F   +RN++
Sbjct:  380 GTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQDNGMNISETFDPDPCSISFQRPTRNIN 492
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Nematostella
Match: EDO32849 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV3])

HSP 1 Score: 60.8474 bits (146), Expect = 7.939e-10
Identity = 38/124 (30.65%), Postives = 60/124 (48.39%), Query Frame = 3 
Query:  456 YGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGGLMRGNC--LLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWE----RPTSEKNET 809
            + QI W +     K+  AK      +FS  F + K+GY+LC + C  G  +G    + V  +++   ++  L WPF + V F L+NQ +E    +K VKF+     +   E    RP  EKN +
Sbjct:  305 HSQIIWRIEDYTRKLKEAKAGNAETLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFVSVLKGAFDALLKWPFHYRVTFFLLNQ-HENPEERKHVKFSIKPNPIPDNEPFLGRPRLEKNAS 427
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Nematostella
Match: EDO32851 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STV5])

HSP 1 Score: 60.8474 bits (146), Expect = 9.208e-10
Identity = 36/124 (29.03%), Postives = 60/124 (48.39%), Query Frame = 3 
Query:  456 YGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGGLMRGNC--LLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKF----NSNSRNVDKWERPTSEKNET 809
            + Q+ W +     KM  AK      +FS  F + K+GY+LC + C  G  +G    + V  +++   ++  L WPF + V F L++Q N+    +K ++F    N  + N     RP  EKN +
Sbjct:  301 HSQLIWRIEDYTRKMKEAKAGNTDTLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFISVLKGAFDALLKWPFDYRVTFVLLDQ-NDDPAQRKHIRFSIKPNPCADNEPFLGRPRLEKNAS 423
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Nematostella
Match: EDO48773 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI91])

HSP 1 Score: 56.6102 bits (135), Expect = 1.754e-8
Identity = 51/216 (23.61%), Postives = 89/216 (41.20%), Query Frame = 3 
Query:  288 NTFDAKADKYSMKVFELKSAEESVKTMEKDNTVNILVK--DVEVFPIELQRTAVISEIYGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLA----ACFGGLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQ---------INETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIK 890
            +   ++ D+Y   +  L+   E VKT        +  K   +E   IEL+         G   W++   ++    +   + + I S PFY+   GYK+CL        GGL  G  + +   +M  +++  L WPF   +   +++Q         I+ET+ AK          N+  ++RPTS +N     Y     ID L      +N+ I ++
Sbjct:  277 DMLGSRGDEYRQFLAYLERKVEDVKTSSDRRIAELTHKLMRLETREIELEGRVC----NGTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGL--GEHVSLFIHMMQGDWDGILEWPFIGRITLSILDQSDQIDSRRPISETLVAKP---------NLLAFQRPTSPRNHKGYGYVEFCPIDQLTEGQYIKNNSILVR 477
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Nematostella
Match: EDO49545 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGK7])

HSP 1 Score: 55.4546 bits (132), Expect = 3.586e-8
Identity = 46/153 (30.07%), Postives = 75/153 (49.02%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKS-EIFSAPFYSHKNGYKLCLAACFGGLMRGNC--LLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVD-KWERPTSEKN-ETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            G   W++   K + + A  S +   IFS PFY+ + GYKL L A   G  RG    L +   +M  +Y+  L WPF   + F LI+Q  +       +  N +  N+   + RPT ++N    N   + N  +VL + +  ++D ++IK V+E
Sbjct:  253 GIFLWKISNYKHQYDQAVASPEELAIFSPPFYTSQYGYKLRLKAYLNGRDRGKGTHLSLYIIIMKGDYDALLEWPFKQKITFYLIDQSEKQNHRTHLLSPNRSLPNIKVVFNRPTVKENLGIGNPCFVPN--EVLESGEYVKDDVMFIKAVVE 403
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764])

HSP 1 Score: 66.6254 bits (161), Expect = 3.375e-11
Identity = 55/209 (26.32%), Postives = 93/209 (44.50%), Query Frame = 3 
Query:  291 TFDAKADKYSMKVFELKSAEESVKTMEKDNTV-NILVKDVEVFPIELQRTAVISEIYGQIF-WEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQIN-ETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            T +A + ++ +   ++++    ++ +E+  TV ++ + + E    ELQ        Y  IF W++     +   A       +FS  FYS K GYK+CL       G  RG  L + F +M S+Y+  L WPF   V   L++Q N E +         S S     ++RP SE N  S       L  +       ++D I+IK +++
Sbjct:  314 TLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCT-----YDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRPDITSTS-----FQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVD 512
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Medaka
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:101159764])

HSP 1 Score: 66.6254 bits (161), Expect = 3.574e-11
Identity = 55/209 (26.32%), Postives = 93/209 (44.50%), Query Frame = 3 
Query:  291 TFDAKADKYSMKVFELKSAEESVKTMEKDNTV-NILVKDVEVFPIELQRTAVISEIYGQIF-WEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFG--GLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQIN-ETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            T +A + ++ +   ++++    ++ +E+  TV ++ + + E    ELQ        Y  IF W++     +   A       +FS  FYS K GYK+CL       G  RG  L + F +M S+Y+  L WPF   V   L++Q N E +         S S     ++RP SE N  S       L  +       ++D I+IK +++
Sbjct:  321 TLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCT-----YDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQNNREHIIDAFRPDITSTS-----FQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVD 519
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428])

HSP 1 Score: 62.7734 bits (151), Expect = 5.145e-10
Identity = 43/157 (27.39%), Postives = 80/157 (50.96%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACF--GGLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKK--TVKFNSNSRNVDKWERPTSEKN---ETSNMYALTNLI--DVLNNDDLYQNDKIWIKGVLE 902
            G + W++     K+  AK     E FS PFY+H+ GYKL ++A     G   G+ L V   ++  EY++ L WPF + V F +++Q + ++   +  T  FN +  N   +++P S +N   E++  +     I  + +   +  +++ I+IK  +E
Sbjct:  308 GVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDP-NWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRNYIRDNCIFIKASIE 463
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428])

HSP 1 Score: 62.7734 bits (151), Expect = 5.852e-10
Identity = 37/119 (31.09%), Postives = 63/119 (52.94%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACF--GGLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKK--TVKFNSNSRNVDKWERPTSEKN 803
            G + W++     K+  AK     E FS PFY+H+ GYKL ++A     G   G+ L V   ++  EY++ L WPF + V F +++Q + ++   +  T  FN +  N   +++P S +N
Sbjct:  308 GVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDP-NWKNFQKPCSTRN 425
[Close]
BLAST of MATH domain-containing protein vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428])

HSP 1 Score: 62.3882 bits (150), Expect = 6.680e-10
Identity = 37/119 (31.09%), Postives = 63/119 (52.94%), Query Frame = 3 
Query:  459 GQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACF--GGLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKK--TVKFNSNSRNVDKWERPTSEKN 803
            G + W++     K+  AK     E FS PFY+H+ GYKL ++A     G   G+ L V   ++  EY++ L WPF + V F +++Q + ++   +  T  FN +  N   +++P S +N
Sbjct:  301 GVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDP-NWKNFQKPCSTRN 418
[Close]
BLAST of MATH domain-containing protein vs. Planmine SMEST
Match: SMESG000026628.1 (SMESG000026628.1)

HSP 1 Score: 99.3673 bits (246), Expect = 6.304e-22
Identity = 51/154 (33.12%), Postives = 85/154 (55.19%), Query Frame = 3 
Query:  456 YGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCL-----AACFGGLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE 902
            +G+  W V    +K+N A+KS+ +E +S  F++HKNGYK+CL        FG   +G+ L + F LM   +++ LSWP  F+V F LI+Q    V   +T +F+ +  N   W +PT+ K      +    + ++L N  ++Q D+I+IK  + 
Sbjct:  293 FGEFVWIVKDFSQKINEARKSINTEFYSDSFFTHKNGYKMCLRVDPIGISFG---KGSHLAIYFCLMQGPFDNILSWPMKFDVTFALIDQSTGYVHMCRTARFDDHPDNF-AWNKPTTNKKIGYGYHKFIEIEELLKNPSIFQEDRIFIKCTVH 442
[Close]
BLAST of MATH domain-containing protein vs. Planmine SMEST
Match: SMESG000001565.1 (SMESG000001565.1)

HSP 1 Score: 97.8265 bits (242), Expect = 1.775e-21
Identity = 58/151 (38.41%), Postives = 85/151 (56.29%), Query Frame = 3 
Query:  456 YGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGGLMR--GNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETS-NMYALTNLIDVLNNDDLYQNDKIWIKGVL 899
            YG+  W++   + K   AK  +  +I S PFYSHKNGYKL L     G+    G  + + F LM  EY+D LSWPF ++V   +INQ  +   A  TV FN      D +E+P +E N+    +Y L  L ++L N++L +ND+I+I  V+
Sbjct:  294 YGKFIWKINNFQLKCQYAKLQITPQITSEPFYSHKNGYKLYLRLYPNGMGEEIGRSVSIFFNLMKGEYDDILSWPFMYDVTLSIINQHTKKPHASHTVYFNEFLDKTD-FEKPINEMNKKGFGVYKLITLNEILQNENLKKNDQIFISCVV 443
[Close]
BLAST of MATH domain-containing protein vs. Planmine SMEST
Match: SMESG000014700.1 (SMESG000014700.1)

HSP 1 Score: 93.9745 bits (232), Expect = 3.601e-20
Identity = 78/301 (25.91%), Postives = 157/301 (52.16%), Query Frame = 3 
Query:   18 QILTDEIKKLQNSVKELKKMNTLIIQEFDLLHKAYLKLKAETQSLGRHFTRIESIRKSDQIIISNLQKIDKNSIHKNFPETQRTNQITGK-NTFDAKADKYSMKVFELKSAEESV-----KTMEKDNTVNILVKDVEV--FPIELQRTAVISEIYGQIF-WEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGGLMRGNCLL-VDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIK 890
            ++L + +  L+N ++ELK   +L+  E   L ++ L+ + +   L +   + E         + ++Q  D N+      + +R ++I+G+      K +K S  +  L+++ E V     K   K +T+   + D ++  F    +   + +++  +IF W++  + + +  AK+S  ++IFS P++  +NGY++CL     GL++      V F +M   Y+D LSWP   +V FELINQ N + F  ++ K+  NS++   +++PT+E+N +        L D+L  +++ + D+I+IK
Sbjct:  123 KLLVEYVNNLRNEIEELKTQMSLVKTENICLIES-LEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFAFAKRLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKS-GVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 421
[Close]
BLAST of MATH domain-containing protein vs. Planmine SMEST
Match: SMESG000014700.1 (SMESG000014700.1)

HSP 1 Score: 93.9745 bits (232), Expect = 4.225e-20
Identity = 78/301 (25.91%), Postives = 157/301 (52.16%), Query Frame = 3 
Query:   18 QILTDEIKKLQNSVKELKKMNTLIIQEFDLLHKAYLKLKAETQSLGRHFTRIESIRKSDQIIISNLQKIDKNSIHKNFPETQRTNQITGK-NTFDAKADKYSMKVFELKSAEESV-----KTMEKDNTVNILVKDVEV--FPIELQRTAVISEIYGQIF-WEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGGLMRGNCLL-VDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIK 890
            ++L + +  L+N ++ELK   +L+  E   L ++ L+ + +   L +   + E         + ++Q  D N+      + +R ++I+G+      K +K S  +  L+++ E V     K   K +T+   + D ++  F    +   + +++  +IF W++  + + +  AK+S  ++IFS P++  +NGY++CL     GL++      V F +M   Y+D LSWP   +V FELINQ N + F  ++ K+  NS++   +++PT+E+N +        L D+L  +++ + D+I+IK
Sbjct:  157 KLLVEYVNNLRNEIEELKTQMSLVKTENICLIES-LEKRGDKSGLEQSKLKEELSALVKDNAVKDIQIKDLNNKINTLIQDRRNDEISGQMKELQEKQEKVSENLDLLQNSNEVVSVRFHKISRKVSTLKESIDDFDMLKFAFAKRLIEITAQLNVKIFVWKIENLSKVIEGAKESNNTKIFSDPYFVSENGYQMCLCVIPNGLVKTKGFFGVYFNVMKGPYDDILSWPCKIDVTFELINQDNGSAFRSESEKYELNSKS-GVYKKPTTERNASFGFPYFIKLKDLLKQEEVIRKDQIFIK 455
[Close]
BLAST of MATH domain-containing protein vs. Planmine SMEST
Match: SMESG000025963.1 (SMESG000025963.1)

HSP 1 Score: 90.1225 bits (222), Expect = 2.362e-19
Identity = 53/147 (36.05%), Postives = 84/147 (57.14%), Query Frame = 3 
Query:  456 YGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLA--ACFGGLMRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFNSNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIK 890
            YG+  W++ K  +KM +AKK + ++I+S  F +HKNG+K+CL       G  +G  L V F LM  E++  L WPF  +V F LINQ        KTVK+ +N+ N +   +PT ++N         +  ++ +N DL +N++I+IK
Sbjct:  187 YGEFVWKLDKFTDKMADAKKGINTDIYSESFLTHKNGFKMCLRVDPDGNGGGKGTHLSVFFCLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSKTVKY-ANNPNSEALIQPT-DRNAGWGFPQFVSHEELSSNPDLMRNNQIFIK 331
The following BLAST results are available for this feature:
BLAST of MATH domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TRAF31.309e-926.16TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF31.898e-926.16TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF31.898e-926.16TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF32.441e-926.16TNF receptor associated factor 3 [Source:HGNC Symb... [more]
TRAF32.441e-926.16TNF receptor associated factor 3 [Source:HGNC Symb... [more]
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BLAST of MATH domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
trf-11.130e-1228.40TNF Receptor Associated Factor (TRAF) homolog; TRF... [more]
trf-21.801e-830.22TNF Receptor Associated Factor (TRAF) homolog [So... [more]
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BLAST of MATH domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MATH domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf2b1.664e-1028.48Tnf receptor-associated factor 2b [Source:ZFIN;Acc... [more]
traf2b1.664e-1028.48Tnf receptor-associated factor 2b [Source:ZFIN;Acc... [more]
traf2b1.745e-1028.48Tnf receptor-associated factor 2b [Source:ZFIN;Acc... [more]
unm_sa8082.483e-1024.40un-named sa808 [Source:ZFIN;Acc:ZDB-GENE-120727-21... [more]
traf54.035e-1025.37Tnf receptor-associated factor 5 [Source:ZFIN;Acc:... [more]
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BLAST of MATH domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sytl21.419e-1032.06synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-9... [more]
ssh22.793e-926.16slingshot protein phosphatase 2 [Source:Xenbase;Ac... [more]
ssh23.785e-926.16slingshot protein phosphatase 2 [Source:Xenbase;Ac... [more]
hspb66.393e-827.03heat shock protein family B (small) member 6 [Sour... [more]
slc12a11.249e-726.97solute carrier family 12 member 1 [Source:Xenbase;... [more]
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BLAST of MATH domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Traf51.529e-1127.89TNF receptor-associated factor 5 [Source:MGI Symbo... [more]
Traf51.529e-1127.89TNF receptor-associated factor 5 [Source:MGI Symbo... [more]
Traf52.492e-1027.89TNF receptor-associated factor 5 [Source:MGI Symbo... [more]
Traf52.492e-1027.89TNF receptor-associated factor 5 [Source:MGI Symbo... [more]
Traf31.482e-926.16TNF receptor-associated factor 3 [Source:MGI Symbo... [more]
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BLAST of MATH domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P70191|TRAF5_MOUSE1.627e-927.89TNF receptor-associated factor 5 OS=Mus musculus O... [more]
sp|Q13114|TRAF3_HUMAN1.172e-826.16TNF receptor-associated factor 3 OS=Homo sapiens O... [more]
sp|Q60803|TRAF3_MOUSE1.333e-826.16TNF receptor-associated factor 3 OS=Mus musculus O... [more]
sp|O00463|TRAF5_HUMAN1.898e-731.97TNF receptor-associated factor 5 OS=Homo sapiens O... [more]
sp|Q13077|TRAF1_HUMAN5.768e-728.29TNF receptor-associated factor 1 OS=Homo sapiens O... [more]
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BLAST of MATH domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A564YXW81.561e-1334.81Uncharacterized protein OS=Hymenolepis diminuta OX... [more]
A0A158RA511.806e-1330.12Uncharacterized protein OS=Taenia asiatica OX=6051... [more]
A0A068Y4Q12.410e-1329.52TNF receptor associated factor 3 OS=Echinococcus m... [more]
A0A1S3KE245.183e-1332.50TNF receptor-associated factor 4 OS=Lingula unguis... [more]
A0A5K3EX785.333e-1332.21Uncharacterized protein OS=Mesocestoides corti OX=... [more]
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BLAST of MATH domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf14.961e-1127.23TNF receptor-associated factor 1-like [Source:NCBI... [more]
traf15.998e-1126.29TNF receptor-associated factor 1-like [Source:NCBI... [more]
ENSAMXT00000035169.11.704e-1030.14pep primary_assembly:Astyanax_mexicanus-2.0:9:3354... [more]
traf2b2.156e-1028.48TNF receptor associated factor 2 [Source:NCBI gene... [more]
traf4a2.634e-1026.75TNF receptor associated factor 4 [Source:NCBI gene... [more]
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BLAST of MATH domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000000074.11.462e-1128.00pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-... [more]
ENSPMAT00000002130.14.556e-923.40pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 g... [more]
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BLAST of MATH domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MATH domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO352371.665e-1134.51Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO328497.939e-1030.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO328519.208e-1029.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO487731.754e-823.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO495453.586e-830.07Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of MATH domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
traf2b3.375e-1126.32TNF receptor associated factor 2 [Source:NCBI gene... [more]
traf2b3.574e-1126.32TNF receptor associated factor 2 [Source:NCBI gene... [more]
traf4a5.145e-1027.39TNF receptor associated factor 4 [Source:NCBI gene... [more]
traf4a5.852e-1031.09TNF receptor associated factor 4 [Source:NCBI gene... [more]
traf4a6.680e-1031.09TNF receptor associated factor 4 [Source:NCBI gene... [more]
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BLAST of MATH domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000026628.16.304e-2233.12SMESG000026628.1[more]
SMESG000001565.11.775e-2138.41SMESG000001565.1[more]
SMESG000014700.13.601e-2025.91SMESG000014700.1[more]
SMESG000014700.14.225e-2025.91SMESG000014700.1[more]
SMESG000025963.12.362e-1936.05SMESG000025963.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026637 ID=SMED30026637|Name=MATH domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1865bp
TAATGAAATCTCAAATCCAAATTTTAACAGATGAAATCAAAAAATTGCAA
AATTCAGTAAAAGAACTGAAAAAAATGAATACTTTAATAATTCAGGAATT
CGATTTATTACATAAAGCCTATTTAAAATTAAAGGCGGAAACCCAATCCT
TGGGTCGGCATTTTACGAGAATAGAAAGTATTCGAAAGTCTGACCAGATA
ATAATAAGTAATCTGCAAAAAATAGACAAAAATTCCATTCATAAAAACTT
TCCAGAAACTCAAAGGACCAATCAAATAACTGGAAAAAATACATTTGACG
CGAAAGCTGATAAATATTCTATGAAAGTTTTCGAATTGAAATCCGCTGAG
GAATCAGTGAAAACTATGGAAAAAGACAACACTGTAAATATCTTAGTCAA
AGATGTTGAAGTTTTCCCAATTGAACTCCAAAGAACAGCTGTTATTTCAG
AGATTTACGGACAGATATTTTGGGAAGTAATTAAGGTGAAAGAAAAAATG
AATAATGCTAAAAAGTCAATGAAAAGTGAAATTTTCAGTGCACCTTTTTA
TTCTCACAAAAATGGCTATAAACTCTGTTTGGCTGCATGTTTTGGAGGTT
TAATGAGAGGAAATTGTTTGTTAGTAGATTTCACTTTAATGAATTCTGAA
TATAACGATCAGTTGTCGTGGCCCTTTCCATTTAATGTGAGGTTTGAATT
GATAAATCAAATTAATGAAACTGTTTTCGCGAAAAAAACAGTAAAATTTA
ATTCAAACTCAAGAAATGTAGACAAATGGGAAAGACCAACTTCTGAAAAG
AATGAAACAAGTAATATGTATGCGTTGACGAATCTCATTGACGTGTTGAA
TAATGACGATCTTTATCAAAATGATAAAATTTGGATAAAAGGAGTTTTGG
AAGAACTCTAGATTATTTACTTATTTGAAAAGATCAGCAAATTTAGTCGA
CTTTTCCAAAGAAGTCGGGACAAATTTTTCTTAAATGTTTCACTTTTTAT
TAGAAAATACTTCCGATATACTAACAAATATCCTCAAATAGTATTGGCTA
TATTAACACGTTGACGGACAATTGCGGCTATAGCCGTCAAAGCGAAGTTC
ACAATGTGGCATGACTGCTATAGCCGTCCAAAACGAAACGGTCGTTTTTA
GACACTACGGCTATAGCAGCACAAATGTGCACTTACTGGCGTATACGTAG
AAGCATAGTGTCGTGTTTTGAAAACATCTTTTTAGGTTGAAGTTCATATT
TCACCTGTTATACGAGTTGCAGATTCAGTATGCACGTGGTTGTGAAGGGA
GTAGTGCGATCGTAGTGTCAATTTTCGAACTTCGCTTGTTCCTACTGTCC
GTCAACGTGTTAAATAAACTCATAACGTTAGAAAAATACTATATTTATCA
CTTGAAATAAAAATAATAAAATTTTCTTTCGGTTTTTGAGGAAAACCCAG
TTTTTGCGGTTATGTGAATTTTAACAAATTCCCGGTTTCGGTTTCCACCG
ATTGCAATCCATAATATCCAGAAAAATGTCTTTTAAATAAGCAGAAAGAA
TATTGAATAGGAAATGGAAATTATATATTTCTTTTAGACTTCTATAAATT
TTTAAATTCCACATGAATGATTGTAGTGATATTTTTATCCATATAAATGA
GATTTGCTATCTGATTTTTAAACTTTTACAGCTATTTGGAAAATTTTCTC
CGGGGCAGTCCACAAATGACGTCACCCGATTTTGGCATATTTTTACCCCT
TCCCCCTTCGTCACACGTCGTCGCGAAAAGTTAGCCACCCTCAAATATGA
CATCAAAAATCTTTGGTCCTCCTGAAAAGCCATATTACATATTTGAAAAT
GAATATGTTTCAAAT
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protein sequence of SMED30026637-orf-1

>SMED30026637-orf-1 ID=SMED30026637-orf-1|Name=SMED30026637-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=303bp
MKSQIQILTDEIKKLQNSVKELKKMNTLIIQEFDLLHKAYLKLKAETQSL
GRHFTRIESIRKSDQIIISNLQKIDKNSIHKNFPETQRTNQITGKNTFDA
KADKYSMKVFELKSAEESVKTMEKDNTVNILVKDVEVFPIELQRTAVISE
IYGQIFWEVIKVKEKMNNAKKSMKSEIFSAPFYSHKNGYKLCLAACFGGL
MRGNCLLVDFTLMNSEYNDQLSWPFPFNVRFELINQINETVFAKKTVKFN
SNSRNVDKWERPTSEKNETSNMYALTNLIDVLNNDDLYQNDKIWIKGVLE
EL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0042981regulation of apoptotic process
GO:0007165signal transduction
GO:0007250activation of NF-kappaB-inducing kinase activity
GO:0016567protein ubiquitination
GO:0046330positive regulation of JNK cascade
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
Vocabulary: INTERPRO
TermDefinition
IPR008974TRAF-like
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0004842ubiquitin-protein transferase activity
GO:0008270zinc ion binding
GO:0046872metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0005622intracellular