Short transient receptor potential channel 4

Overview


Name	Short transient receptor potential channel 4
Smed ID	SMED30026628
Length (bp)	3375

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Short transient receptor potential channel 4 (SMED30026628) t-SNE clustered cells

Violin plots show distribution of expression levels for Short transient receptor potential channel 4 (SMED30026628) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Short transient receptor potential channel 4 (SMED30026628) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30026628

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30026628	h1SMcG0010319	SmedASXL_014057	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
nervous system	SMED30026628	h1SMcG0010319	dd_Smed_v4_20495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30026628	h1SMcG0010319	dd_Smed_v4_20495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30026628	h1SMcG0010319	dd_Smed_v4_20495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30026628	h1SMcG0010319	dd_Smed_v4_20495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30026628	h1SMcG0010319	dd_Smed_v4_20495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30026628	h1SMcG0010319	dd_Smed_v4_20495_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30026628	h1SMcG0010319	dd_Smed_v6_20495_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
photoreceptor neuron	SMED30026628	h1SMcG0010319	SMED30026628	smed_20140614	PMID:22884275 Lapan et al., 2012
head region	SMED30026628	h1SMcG0010319	OX_Smed_1.0.22073	ox_Smed_v2	PMID:24238224 Kao et al., 2013

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Match: TRPC4 (transient receptor potential cation channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:12336])

HSP 1 Score: 669.463 bits (1726), Expect = 0.000e+0
Identity = 365/778 (46.92%), Postives = 506/778 (65.04%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFI-LILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARH---QIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKT 2669
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+     N++          E +    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +     +I   FP  S+ Y+++PKS LG  +++PFIKF+CH  SY+ FL  L + +  ++          L+ +GPPP+I EW I+ ++ G+IW EIKQ++  GL+ Y+ D WNL+DF  N+LY A   L+I A+         +  R+ W+ + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +   CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFN+IPSPKS  Y I  I  H    C +   R K +S   + ++  +   RH   Q VM++L+KRY+    + A   +G+TE++  E+K DISSFRFE++ + + + + T
Sbjct:   25 AESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDD--NSL---------IEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-------RSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKY----SALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH---LCKKKMRR-KPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Match: TRPC4 (transient receptor potential cation channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:12336])

HSP 1 Score: 668.307 bits (1723), Expect = 0.000e+0
Identity = 365/778 (46.92%), Postives = 506/778 (65.04%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFI-LILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARH---QIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKT 2669
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+     N++          E +    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +     +I   FP  S+ Y+++PKS LG  +++PFIKF+CH  SY+ FL  L + +  ++          L+ +GPPP+I EW I+ ++ G+IW EIKQ++  GL+ Y+ D WNL+DF  N+LY A   L+I A+         +  R+ W+ + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +   CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFN+IPSPKS  Y I  I  H    C +   R K +S   + ++  +   RH   Q VM++L+KRY+    + A   +G+TE++  E+K DISSFRFE++ + + + + T
Sbjct:   25 AESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDD--NSL---------IEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-------RSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKY----SALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH---LCKKKMRR-KPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Match: TRPC4 (transient receptor potential cation channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:12336])

HSP 1 Score: 667.152 bits (1720), Expect = 0.000e+0
Identity = 364/782 (46.55%), Postives = 504/782 (64.45%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFI-LILKHCLFCCSESHNRSKWK----SIRKLVKKVNEKEARH---QIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKT 2669
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+     N++          E +    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +     +I   FP  S+ Y+++PKS LG  +++PFIKF+CH  SY+ FL  L + +  ++          L+ +GPPP+I EW I+ ++ G+IW EIKQ++  GL+ Y+ D WNL+DF  N+LY A   L+I A+         +  R+ W+ + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +   CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFN+IPSPKS  Y I  I  H    C +   R         +R   ++  +   RH   Q VM++L+KRY+    + A   +G+TE++  E+K DISSFRFE++ + + + + T
Sbjct:   25 AESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDD--NSL---------IEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-------RSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKY----SALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH---LCKKKMRRKPESFGTIGVRTQHRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 766

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Match: TRPC5 (transient receptor potential cation channel subfamily C member 5 [Source:HGNC Symbol;Acc:HGNC:12337])

HSP 1 Score: 651.744 bits (1680), Expect = 0.000e+0
Identity = 351/783 (44.83%), Postives = 504/783 (64.37%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNH--DHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQ---RQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNE---KEARHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTP 2672
             E ELS +E+ +L +VE+GD   VK  L     Y  +NINC D LGR+AL IAIENE+ E++ELLL++++ + D+LL+AI +E + AVE+LL+      +K+    ++    + FT DITP++LAAH +NY IIK+L+ +  TIP+PH +RC C ECV S + DSLRHSRSR+N Y+ALASPSLI LSS+DPILTAF L WEL  L  +ENEFK +YE L++QC+ FA DLL Q R S EL  ILNH  DH             E  + ++   L++LK+AIKY QK FV  P+CQQLL++LWY+G PG RR  ++ +      I   FP +S+ Y++SP+S LG  +K+PFIKF+CH  SY+ FL  L + +  +           L  +GPPP++ EW I+ ++ G+IW EIK+++  G   Y+ D WNL+DF+ N+LY A   L+I AY     S      R+ WE + P LI+E LFA +NILS ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y  +       CKG+                C  +   FS +FE +QSL+W+ FGL++L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+F+EGGT P PFNIIPSPKS  Y      +      +   R + +++R   ++  +   +   +Q V+++L+KRY+    + +  ++G+TE++  E+K DISSFR+E++++  + N K P
Sbjct:   25 AETELSAEEKAFLNAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRRPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHS------------EELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHI-------VRTDLHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSRP----REEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGI---------------RCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRRNLRSFTERNADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTHEGLTEENFKELKQDISSFRYEVLDL--LGNRKHP 767

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Match: TRPC4 (transient receptor potential cation channel subfamily C member 4 [Source:HGNC Symbol;Acc:HGNC:12336])

HSP 1 Score: 639.802 bits (1649), Expect = 0.000e+0
Identity = 350/735 (47.62%), Postives = 479/735 (65.17%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFI-LILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARH---QIVMKDLIKRYL 2543
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+     N++          E +    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +     +I   FP  S+ Y+++PKS LG  +++PFIKF+CH  SY+ FL  L + +  ++          L+ +GPPP+I EW I+ ++ G+IW EIKQ++  GL+ Y+ D WNL+DF  N+LY A   L+I A+         +  R+ W+ + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +   CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFN+IPSPKS  Y I  I  H    C +   R K +S   + ++  +   RH   Q VM++L+KRY+
Sbjct:   25 AESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDD--NSL---------IEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-------RSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKY----SALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH---LCKKKMRR-KPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYV 718

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Match: trp-2 (TRP (Transient receptor potential) channel family; TRP homlogous cation channel protein [Source:UniProtKB/TrEMBL;Acc:G5EE02])

HSP 1 Score: 659.062 bits (1699), Expect = 0.000e+0
Identity = 352/757 (46.50%), Postives = 496/757 (65.52%), Query Frame = 3

Query:  330 EKSGISSNTEEELSDD----ERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPK---KKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMK---VEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDST--------DRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEAC---------KGVVFTYSITGQEL-ERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIR--KLVKKVNEKEARHQ 2510
            +   +S+N     SD+    E+++LLS ERGD   V+ +L   +    NINC D LGR AL IAIENE+ EM+ELLL +N+E  D++L+AI EEN+EAVEI++  +    K   ++  +++  +S  AFT DITP++LAAH+DNY  IK+ LD+  T+P PHD+RC+C EC  +++EDSLR SRSRINAYRAL SPSLICLS++DPIL AFELSWEL RL  +ENEF+TDYE L+++CQKF   +L Q RGS EL  +LNH     + ++       SA       L+RLKLAI+  QK FV HP+CQQLL  +WYEG+  +R   FI++     L   SFP  S+ Y+L+P S +G   K+PFIKFL H GSY+ FL+ L + + +   ++ IL  + V+R   RGPPP+I E AI +++ G IW EIKQL+  GL  Y  ++WN+LDF TN+LY     LR+ AY  ++            R + R+ W+A++P L+SEC FA ANI S +KLV +FT++P LGPL+ISLGRM+ DI+ FF +Y LVL A+A G++QLLW+Y+  RQ  C         K + + Y    +   ++Y+ C       S+I+   ++L+W  FGL+DLT+  L+ DH  +E+ GK + GSYC  SII+LLNM IAMM+ SYQ I++++D EWKFARS+L++ +F++  T P PFNI+PSPKS  Y +  L   L  C++    SK KS+R  K+++ VN++E  ++
Sbjct:   14 DDDDVSNNVTWTESDNSRLREKQFLLSCERGDIGSVRKLLAGISTETFNINCLDPLGRNALLIAIENENIEMIELLLDHNIETGDAILYAIGEENVEAVEIIVEHLEKMDKFDSERQGVEITEHS--AFTPDITPIVLAAHKDNYECIKLFLDKKGTVPHPHDVRCSCPECYVAREEDSLRLSRSRINAYRALTSPSLICLSARDPILYAFELSWELKRLSFIENEFRTDYEELSQKCQKFCVHMLDQVRGSKELEVVLNHTTNAWHDVT-------SANYGNPEKLARLKLAIQLSQKRFVAHPNCQQLLLDIWYEGVESVRCTNFIYKLIFYILGMLSFPLFSLVYLLAPHSSMGQFAKKPFIKFLSHSGSYIFFLILLIMASQRMNVIDNILRTDDVDRKETRGPPPTIIECAIFLWVLGLIWVEIKQLWECGLYNYCRNLWNILDFITNSLYLCTTALRVVAYVQVEQEALRANSVHIARHLPRRDWDAWDPTLLSECFFATANIFSSLKLVHIFTVSPHLGPLKISLGRMVIDIVKFFMVYALVLFAFACGLNQLLWYYASMRQNECNLYEQYKNEKSLSYKYEHLKESCDDKYKSC-------SSIYHTAETLFWALFGLVDLTHFRLKEDHFLSEWTGKTIFGSYCCCSIIVLLNMLIAMMSNSYQYISDQADIEWKFARSRLFLEYFDDTATLPPPFNIVPSPKSIYYCLHYLTKKLCNCTKLQQPSKQKSMRNQKILRSVNDRENNYR 754

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Match: trp-2 (TRP (Transient receptor potential) channel family; TRP homlogous cation channel protein [Source:UniProtKB/TrEMBL;Acc:G5EE02])

HSP 1 Score: 655.21 bits (1689), Expect = 0.000e+0
Identity = 348/741 (46.96%), Postives = 485/741 (65.45%), Query Frame = 3

Query:  330 EKSGISSNTEEELSDD----ERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPK---KKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMK---VEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDST--------DRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEAC---------KGVVFTYSITGQEL-ERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIR 2468
            +   +S+N     SD+    E+++LLS ERGD   V+ +L   +    NINC D LGR AL IAIENE+ EM+ELLL +N+E  D++L+AI EEN+EAVEI++  +    K   ++  +++  +S  AFT DITP++LAAH+DNY  IK+ LD+  T+P PHD+RC+C EC  +++EDSLR SRSRINAYRAL SPSLICLS++DPIL AFELSWEL RL  +ENEF+TDYE L+++CQKF   +L Q RGS EL  +LNH     + ++       SA       L+RLKLAI+  QK FV HP+CQQLL  +WYEG+  +R   FI++     L   SFP  S+ Y+L+P S +G   K+PFIKFL H GSY+ FL+ L + + +   ++ IL  + V+R   RGPPP+I E AI +++ G IW EIKQL+  GL  Y  ++WN+LDF TN+LY     LR+ AY  ++            R + R+ W+A++P L+SEC FA ANI S +KLV +FT++P LGPL+ISLGRM+ DI+ FF +Y LVL A+A G++QLLW+Y+  RQ  C         K + + Y    +   ++Y+ C       S+I+   ++L+W  FGL+DLT+  L+ DH  +E+ GK + GSYC  SII+LLNM IAMM+ SYQ I++++D EWKFARS+L++ +F++  T P PFNI+PSPKS  Y +  L   L  C++    SK KS+R
Sbjct:   14 DDDDVSNNVTWTESDNSRLREKQFLLSCERGDIGSVRKLLAGISTETFNINCLDPLGRNALLIAIENENIEMIELLLDHNIETGDAILYAIGEENVEAVEIIVEHLEKMDKFDSERQGVEITEHS--AFTPDITPIVLAAHKDNYECIKLFLDKKGTVPHPHDVRCSCPECYVAREEDSLRLSRSRINAYRALTSPSLICLSARDPILYAFELSWELKRLSFIENEFRTDYEELSQKCQKFCVHMLDQVRGSKELEVVLNHTTNAWHDVT-------SANYGNPEKLARLKLAIQLSQKRFVAHPNCQQLLLDIWYEGVESVRCTNFIYKLIFYILGMLSFPLFSLVYLLAPHSSMGQFAKKPFIKFLSHSGSYIFFLILLIMASQRMNVIDNILRTDDVDRKETRGPPPTIIECAIFLWVLGLIWVEIKQLWECGLYNYCRNLWNILDFITNSLYLCTTALRVVAYVQVEQEALRANSVHIARHLPRRDWDAWDPTLLSECFFATANIFSSLKLVHIFTVSPHLGPLKISLGRMVIDIVKFFMVYALVLFAFACGLNQLLWYYASMRQNECNLYEQYKNEKSLSYKYEHLKESCDDKYKSC-------SSIYHTAETLFWALFGLVDLTHFRLKEDHFLSEWTGKTIFGSYCCCSIIVLLNMLIAMMSNSYQYISDQADIEWKFARSRLFLEYFDDTATLPPPFNIVPSPKSIYYCLHYLTKKLCNCTKLQQPSKQKSMR 738

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Match: trp-1 (Transient-receptor-potential-like protein [Source:UniProtKB/Swiss-Prot;Acc:P34586])

HSP 1 Score: 519.235 bits (1336), Expect = 2.196e-166
Identity = 310/848 (36.56%), Postives = 480/848 (56.60%), Query Frame = 3

Query:  306 NFDIQTGLEKSGISSNTEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSY-NLEIADSLLHAISEENIEAVEILLT-AMATRPKKKD----LLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNY--VERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAY--FNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCC--------SESHNRSKWKSIRK--LVKKVNEKEAR------------HQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAY--TTLRNVTKLRHKGSKKGFNRIMR 2747
            N+ +      + +   T + +S +ER++L + E G+ P ++  LD      LN+NC DS+GRTAL IA++NE+ E++ELLL   ++ I ++LL AI E     VE+L+     TR    D     LD    +S  ++SDI+P+ILAA  + + I+++L+ +  +I KPH   C C  C + +  DSL++S  RIN +RALASP+ + L+S DPIL+AF+LSW+L RL   E+EFK  Y  L+EQC++++ DLL+Q R S E+  ILN D G VN  +I             ++LSRLKLAIKY+QK+FV HPHCQQLL+S+WYEG+P  +R        +   +   +P   + YIL PKS+LG +++ PF+KF  +  S+  FL  LT    +      G    + R SDRGPP +  E  +  ++ G +W EIKQL+  G + Y+   WN LDF    LY     +R++AY  F  ++   R   R YW + EP+L++E LFA  N+ S  +++++F  NP LGPLQISLG ML D+  F  ++VL++ +++ G+ QL W+Y         G                 C      FS+I +   +L W+ F +    + ++  +H+ T+++G+ M   Y   SII+LLNM IAMM+ S+QII + +D EWKF R++LW++ F+EG + P PFNII +PKS  Y +    +CLF          +   NR++  +IR+    +K NE E              +  ++  L+ R++ Q +K  +  GV EDDL+EIK DISS R+EL +  +   +++ ++     R++ +     S++ +   MR
Sbjct:   26 NYALANIPPPAAVHIRTNDMISPEERRFLEAAELGNKPTLQECLDYDGDRRLNVNCLDSMGRTALEIAVDNENMEVVELLLQQPDIRIGNALLCAIREGVYRLVEVLVNHPNITREMLGDGWSQALDPSEAASAEYSSDISPVILAAQLNQFEILQMLIRKDASIEKPHRHSCICETCDRERLNDSLQYSLKRINTFRALASPAWMSLTSPDPILSAFKLSWDLQRLAFEEHEFKETYLQLSEQCKQYSCDLLSQCRSSEEVIAILNKD-GNVNDDNIDVW-------ASKLSLSRLKLAIKYEQKAFVSHPHCQQLLTSIWYEGIPYRQRSGTWANFFLYAFLLFLWPIFCLMYILMPKSRLGRLVRSPFMKFFYYSVSFATFLGLLTWATFEDYRYEKGERGGMTRASDRGPPATWVESLVFTWVIGMLWSEIKQLWEEGFKRYMRQWWNWLDFLMICLYLCTISIRLSAYYIFTYREDPYRYTVRTYWTSEEPMLVAEALFAVGNVFSFARIIYLFQTNPYLGPLQISLGCMLVDVAKFCFIFVLIISSFSIGLAQLYWYYDPNTDVCLPGAT---------------CKHSSNVFSSIADSYLTLLWSLFSITKPEDTDVVENHKITQWVGQGMFIMYHCTSIIVLLNMLIAMMSHSFQIINDHADLEWKFHRTKLWMAHFDEGSSLPPPFNIIVTPKSLIYVM----NCLFNTVRWLLGKYTYQKNRNR-ATIRRPGYSRKRNEMEKSGGHDDDSLKPLTYADIITRLVARFIHQTKKDMKMDGVNEDDLHEIKQDISSLRYELRDDRRREIVRSSSHIDAVKRDIMRTMSTTSRRPYGGSMR 845

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Match: trp-1 (Transient-receptor-potential-like protein [Source:UniProtKB/Swiss-Prot;Acc:P34586])

HSP 1 Score: 512.301 bits (1318), Expect = 1.644e-163
Identity = 307/828 (37.08%), Postives = 472/828 (57.00%), Query Frame = 3

Query:  366 LSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSY-NLEIADSLLHAISEENIEAVEILLT-AMATRPKKKD----LLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNY--VERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAY--FNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCC--------SESHNRSKWKSIRK--LVKKVNEKEAR------------HQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAY--TTLRNVTKLRHKGSKKGFNRIMR 2747
            LS++  ++L + E G+ P ++  LD      LN+NC DS+GRTAL IA++NE+ E++ELLL   ++ I ++LL AI E     VE+L+     TR    D     LD    +S  ++SDI+P+ILAA  + + I+++L+ +  +I KPH   C C  C + +  DSL++S  RIN +RALASP+ + L+S DPIL+AF+LSW+L RL   E+EFK  Y  L+EQC++++ DLL+Q R S E+  ILN D G VN  +I             ++LSRLKLAIKY+QK+FV HPHCQQLL+S+WYEG+P  +R        +   +   +P   + YIL PKS+LG +++ PF+KF  +  S+  FL  LT    +      G    + R SDRGPP +  E  +  ++ G +W EIKQL+  G + Y+   WN LDF    LY     +R++AY  F  ++   R   R YW + EP+L++E LFA  N+ S  +++++F  NP LGPLQISLG ML D+  F  ++VL++ +++ G+ QL W+Y         G                 C      FS+I +   +L W+ F +    + ++  +H+ T+++G+ M   Y   SII+LLNM IAMM+ S+QII + +D EWKF R++LW++ F+EG + P PFNII +PKS  Y +    +CLF          +   NR++  +IR+    +K NE E              +  ++  L+ R++ Q +K  +  GV EDDL+EIK DISS R+EL +  +   +++ ++     R++ +     S++ +   MR
Sbjct:   66 LSNNLFRFLEAAELGNKPTLQECLDYDGDRRLNVNCLDSMGRTALEIAVDNENMEVVELLLQQPDIRIGNALLCAIREGVYRLVEVLVNHPNITREMLGDGWSQALDPSEAASAEYSSDISPVILAAQLNQFEILQMLIRKDASIEKPHRHSCICETCDRERLNDSLQYSLKRINTFRALASPAWMSLTSPDPILSAFKLSWDLQRLAFEEHEFKETYLQLSEQCKQYSCDLLSQCRSSEEVIAILNKD-GNVNDDNIDVW-------ASKLSLSRLKLAIKYEQKAFVSHPHCQQLLTSIWYEGIPYRQRSGTWANFFLYAFLLFLWPIFCLMYILMPKSRLGRLVRSPFMKFFYYSVSFATFLGLLTWATFEDYRYEKGERGGMTRASDRGPPATWVESLVFTWVIGMLWSEIKQLWEEGFKRYMRQWWNWLDFLMICLYLCTISIRLSAYYIFTYREDPYRYTVRTYWTSEEPMLVAEALFAVGNVFSFARIIYLFQTNPYLGPLQISLGCMLVDVAKFCFIFVLIISSFSIGLAQLYWYYDPNTDVCLPGAT---------------CKHSSNVFSSIADSYLTLLWSLFSITKPEDTDVVENHKITQWVGQGMFIMYHCTSIIVLLNMLIAMMSHSFQIINDHADLEWKFHRTKLWMAHFDEGSSLPPPFNIIVTPKSLIYVM----NCLFNTVRWLLGKYTYQKNRNR-ATIRRPGYSRKRNEMEKSGGHDDDSLKPLTYADIITRLVARFIHQTKKDMKMDGVNEDDLHEIKQDISSLRYELRDDRRREIVRSSSHIDAVKRDIMRTMSTTSRRPYGGSMR 865

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Match: spe-41 (TRP homologous cation channel protein; TRP-3 channel protein [Source:UniProtKB/TrEMBL;Acc:G5EF09])

HSP 1 Score: 113.235 bits (282), Expect = 3.502e-25
Identity = 132/629 (20.99%), Postives = 266/629 (42.29%), Query Frame = 3

Query:  576 LLHAISEENIEAVEILLTAMATRPKKKDLLDLL--------GNSSNA--FTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSR-INAYRALASPSLICLSSKDPILTAFELSWELNRLGILEN-EFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSL----WYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIW----QEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTD-RMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFG---------LIDLTNLNLE-YDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNII 2369
            L+   SEE+++   +L  A+ +RP  + +L L           S+N+  F   +TPL+LA   +N+ I++ L+ RG  I  PH + C C  C   ++E    HS +R ++  RAL+S + + L++ D       ++ +L +L   +  E+   Y  L    Q+F   +       S+ A  ++  +  V   +  P RM    S       RL++A+  + + F    + Q  + S+    WY      +R  +    A     C   P + M +   P    G+ +  P  +F+ H   Y++FL+   +      +  + + +E          ++  A+ I++  Y+     ++    Y  G   + A  W   D +          +  T  +  +++ D   ++R +W ++E  L+ E   A A +LS++K  +   +   +G   IS+G+ +     +  + V ++V+++ G++ ++  Y ++          T  I  Q+     Y  T   Y   I    ++L+W+ FG         ++  T  N++   H       +++   Y  I II +LN+  +++      + +  + E+KF R+ ++  F       P P N+I
Sbjct:   91 LMDTSSEESLKEALLLSIAVGSRPLVEFVLVLFVDAPYLERSGSANSPHFPPHMTPLMLACILNNFSIVQCLITRGHCIQIPHFITCECKTC---KRETVTTHSSTRLVDVMRALSSEAYLWLATDDVFAATCAVARDLQQLASDDQLEYVETYRDLEMNVQRFLCRI-------SDQAWRVDEFNMMVANRNYCPERMTEISS------PRLQMAMDSQMRQFTCSTNSQTTIKSVFRSDWYNYGIKPKRDAWRFLRA-----CILMPFLVMLHAFMPTK--GTTMCVPLARFIAHITMYLVFLIAAILRPTIGFYFAWTDSIE----------VTVQALEIFMYAYVMGLALEKGILFYRVGRDGFFAFWWRWFD-AALIFIFLFSLIFFTGKWGKREAFDPSSVDRMHWPSFEFSLLHEICLAIACVLSILKCFYYAQMMKSIGGSVISVGKCVGKTYTYILIMVAIIVSFSVGLNIIVDPYLNRS---------TMKIGDQD-----YTKTTDSY-ETIGTSSKNLFWSIFGYLGPSTFTTVVGNTGPNMDPVKHTLNSSTFEILAAVYHGILIITVLNLMTSILVKGADEVLDNEEMEFKFTRAAIYSEFLSWEMAAPPPLNLI 670

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Match: Trpgamma (gene:FBgn0032593 transcript:FBtr0335144)

HSP 1 Score: 767.689 bits (1981), Expect = 0.000e+0
Identity = 400/814 (49.14%), Postives = 545/814 (66.95%), Query Frame = 3

Query:  363 ELSDDERKYLLSVERGDAPYVKSILDN-KNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTA--MATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFG----------NYVERL-SDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMK-----DSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKT--PAYTTLRNVTKLRHKGSK--KGFN 2735
            +L+ +E+K+LL+VERGD    + +L   ++   +N+NC D LGRTAL +AI+NE+ EM+ELL++YN++  D+LLH+ISEE +EAVE+LL    +    +     +     ++ FT DITPLILAAHRDNY IIKILLDRG  +P PHD+RC C ECV+S++EDSLRHSRSRINAYRALASPSLI LSSKDPILTAFELSWEL RL  LE+EFK +Y+ L +QCQ FAT LL  TR S EL  +LNHD          P+     E  E M L+RLKLAIK +QK FV H + QQLL+S+WYEGLPG RR     Q+  I  I   FP  S+ YIL+P S +G  +++PFIKF+CH  SY  FL  L + + ++E  + G          N +E L + RG  P+  EW I+ +++G IW E+KQL+  GL+ YL DMWN++DF TN+LY A   LR+ ++F ++     +S    + R+ W+A++P+LISE LF+AANI S +KLV++F++NP LGPLQ+SL RM+ DI+ FF +YVLVL A+  G++QLLW+Y+   ++ C  V    ++               R FSN+FE  Q+L+W  FGLIDL +  L+    FT F G LM G+Y  I+I++LLN+ IAMMN SYQ+I+E++D EWKFARS+LWIS+FEEGGT P PFNIIP+PKS  Y I  ++      S +  R   K+IR+  ++ ++++ ++Q +M++L++RY+   Q+  E+QGVTEDD+NEIK DIS+FR EL+EI K + M T   A        K R K  +  KGFN
Sbjct:   77 QLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNHD-------PTGPVY----EHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMIYNSHATDLPRERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDPNACIVWRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQDISAFRCELVEILKNSGMDTNVTAGQGGGGGKKNRQKERRLMKGFN 879

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Match: Trpgamma (gene:FBgn0032593 transcript:FBtr0080945)

HSP 1 Score: 766.148 bits (1977), Expect = 0.000e+0
Identity = 399/822 (48.54%), Postives = 549/822 (66.79%), Query Frame = 3

Query:  363 ELSDDERKYLLSVERGDAPYVKSILDN-KNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTA--MATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFG----------NYVERL-SDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMK-----DSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIMRKTNL--PG 2765
            +L+ +E+K+LL+VERGD    + +L   ++   +N+NC D LGRTAL +AI+NE+ EM+ELL++YN++  D+LLH+ISEE +EAVE+LL    +    +     +     ++ FT DITPLILAAHRDNY IIKILLDRG  +P PHD+RC C ECV+S++EDSLRHSRSRINAYRALASPSLI LSSKDPILTAFELSWEL RL  LE+EFK +Y+ L +QCQ FAT LL  TR S EL  +LNHD          P+     E  E M L+RLKLAIK +QK FV H + QQLL+S+WYEGLPG RR     Q+  I  I   FP  S+ YIL+P S +G  +++PFIKF+CH  SY  FL  L + + ++E  + G          N +E L + RG  P+  EW I+ +++G IW E+KQL+  GL+ YL DMWN++DF TN+LY A   LR+ ++F ++     +S    + R+ W+A++P+LISE LF+AANI S +KLV++F++NP LGPLQ+SL RM+ DI+ FF +YVLVL A+  G++QLLW+Y+   ++ C  V    ++               R FSN+FE  Q+L+W  FGLIDL +  L+    FT F G LM G+Y  I+I++LLN+ IAMMN SYQ+I+E++D EWKFARS+LWIS+FEEGGT P PFNIIP+PKS  Y I  ++      S +  R   K+IR+  ++ ++++ ++Q +M++L++RY+   Q+  E+QGVTEDD+NEIK DIS+FR EL+EI K + M T    T         K +++   R+M+  N+  PG
Sbjct:   16 QLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNHD-------PTGPVY----EHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMIYNSHATDLPRERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDPNACIVWRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQDISAFRCELVEILKNSGMDT--NVTAGQGGGGGGKKNRQKERRLMKGFNIAPPG 824

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Match: Trpgamma (gene:FBgn0032593 transcript:FBtr0080946)

HSP 1 Score: 766.148 bits (1977), Expect = 0.000e+0
Identity = 399/822 (48.54%), Postives = 549/822 (66.79%), Query Frame = 3

Query:  363 ELSDDERKYLLSVERGDAPYVKSILDN-KNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTA--MATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFG----------NYVERL-SDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMK-----DSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIMRKTNL--PG 2765
            +L+ +E+K+LL+VERGD    + +L   ++   +N+NC D LGRTAL +AI+NE+ EM+ELL++YN++  D+LLH+ISEE +EAVE+LL    +    +     +     ++ FT DITPLILAAHRDNY IIKILLDRG  +P PHD+RC C ECV+S++EDSLRHSRSRINAYRALASPSLI LSSKDPILTAFELSWEL RL  LE+EFK +Y+ L +QCQ FAT LL  TR S EL  +LNHD          P+     E  E M L+RLKLAIK +QK FV H + QQLL+S+WYEGLPG RR     Q+  I  I   FP  S+ YIL+P S +G  +++PFIKF+CH  SY  FL  L + + ++E  + G          N +E L + RG  P+  EW I+ +++G IW E+KQL+  GL+ YL DMWN++DF TN+LY A   LR+ ++F ++     +S    + R+ W+A++P+LISE LF+AANI S +KLV++F++NP LGPLQ+SL RM+ DI+ FF +YVLVL A+  G++QLLW+Y+   ++ C  V    ++               R FSN+FE  Q+L+W  FGLIDL +  L+    FT F G LM G+Y  I+I++LLN+ IAMMN SYQ+I+E++D EWKFARS+LWIS+FEEGGT P PFNIIP+PKS  Y I  ++      S +  R   K+IR+  ++ ++++ ++Q +M++L++RY+   Q+  E+QGVTEDD+NEIK DIS+FR EL+EI K + M T    T         K +++   R+M+  N+  PG
Sbjct:   16 QLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNHD-------PTGPVY----EHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMIYNSHATDLPRERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDPNACIVWRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQDISAFRCELVEILKNSGMDT--NVTAGQGGGGGGKKNRQKERRLMKGFNIAPPG 824

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Match: trpl (gene:FBgn0005614 transcript:FBtr0088471)

HSP 1 Score: 632.869 bits (1631), Expect = 0.000e+0
Identity = 341/780 (43.72%), Postives = 495/780 (63.46%), Query Frame = 3

Query:  396 SVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMAT-----RPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKV--EFI-LFGNYV-------ERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNM-----KDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQY---CITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNM 2663
            +VERGD P V+ IL    ++  +NINC D LGR AL +AI+NE+ EM+ELL+   +E  D+LLHAI+ E +EAVE+LL           P     +D+   ++  F  DITPL+LAAH++N+ I++ILLDRG  +P PHD+RC C ECV+   EDSLRHS SR+N YRAL SPSLICL+S DPI+TAF+LSWEL  L + E E K++Y  L  QCQKFA DLL QTR S+ELA ILN+D            +M S E  + M+L+RL  AI YKQK FV H + QQLLSS+WY+GLPG RR   + +   I  +   FP   + Y+ +P  + G ++++PF+KFL H  SY+ FL  L + + +   +F+ +FG          + L  RG  PS  E  +++Y+ G++W+E++++++ G+++YL +MWN +DF  N+LY +   LR  AY        +D     I R+ W  ++P LI+E LFAAAN+ S +KLV +F+INP LGPLQISLGRM+ DI+ FF +Y LVL A+A G++QLLW+++   +  C      Y + G E +   +   C+ + R F N+FE  QSL+W +FG++ L +  L     +T F G LM GSY  I++I+LLN+ IAMM+ SY +I E SD EWKFAR++LW+S+FE+  T P PFN++P   S K+ I I +      S++ +R + K      +K  E+ + +  +M+ L+ RY+    +  EN  V+EDD+NE+K +I++ R+E++EIF+ + M
Sbjct:   48 AVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMGVETKDALLHAINAEFVEAVELLLEHEELIYKEGEPYSWQKVDI---NTAMFAPDITPLMLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPSLICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNYDP-----------QMSSYEPGDRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQVAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFGTTRMKKELAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATEIARDPQMAYIPREKWHDFDPQLIAEGLFAAANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEKSKC------YVLPGGEADWGSHGDSCM-KWRRFGNLFESSQSLFWASFGMVGLDDFELSGIKSYTRFWGLLMFGSYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYFEDSATLPPPFNVLP---SVKWVIRIFRK----SSKTIDRQRSKK-----RKEQEQFSEYDNIMRSLVWRYVAAMHRKFENNPVSEDDINEVKSEINTMRYEMLEIFENSGM 794

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Match: trpl (gene:FBgn0005614 transcript:FBtr0301662)

HSP 1 Score: 632.869 bits (1631), Expect = 0.000e+0
Identity = 341/780 (43.72%), Postives = 495/780 (63.46%), Query Frame = 3

Query:  396 SVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMAT-----RPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKV--EFI-LFGNYV-------ERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNM-----KDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQY---CITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNM 2663
            +VERGD P V+ IL    ++  +NINC D LGR AL +AI+NE+ EM+ELL+   +E  D+LLHAI+ E +EAVE+LL           P     +D+   ++  F  DITPL+LAAH++N+ I++ILLDRG  +P PHD+RC C ECV+   EDSLRHS SR+N YRAL SPSLICL+S DPI+TAF+LSWEL  L + E E K++Y  L  QCQKFA DLL QTR S+ELA ILN+D            +M S E  + M+L+RL  AI YKQK FV H + QQLLSS+WY+GLPG RR   + +   I  +   FP   + Y+ +P  + G ++++PF+KFL H  SY+ FL  L + + +   +F+ +FG          + L  RG  PS  E  +++Y+ G++W+E++++++ G+++YL +MWN +DF  N+LY +   LR  AY        +D     I R+ W  ++P LI+E LFAAAN+ S +KLV +F+INP LGPLQISLGRM+ DI+ FF +Y LVL A+A G++QLLW+++   +  C      Y + G E +   +   C+ + R F N+FE  QSL+W +FG++ L +  L     +T F G LM GSY  I++I+LLN+ IAMM+ SY +I E SD EWKFAR++LW+S+FE+  T P PFN++P   S K+ I I +      S++ +R + K      +K  E+ + +  +M+ L+ RY+    +  EN  V+EDD+NE+K +I++ R+E++EIF+ + M
Sbjct:   48 AVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMGVETKDALLHAINAEFVEAVELLLEHEELIYKEGEPYSWQKVDI---NTAMFAPDITPLMLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPSLICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNYDP-----------QMSSYEPGDRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQVAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFGTTRMKKELAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATEIARDPQMAYIPREKWHDFDPQLIAEGLFAAANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEKSKC------YVLPGGEADWGSHGDSCM-KWRRFGNLFESSQSLFWASFGMVGLDDFELSGIKSYTRFWGLLMFGSYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYFEDSATLPPPFNVLP---SVKWVIRIFRK----SSKTIDRQRSKK-----RKEQEQFSEYDNIMRSLVWRYVAAMHRKFENNPVSEDDINEVKSEINTMRYEMLEIFENSGM 794

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Match: trpc4b (transient receptor potential cation channel, subfamily C, member 4b [Source:ZFIN;Acc:ZDB-GENE-120329-1])

HSP 1 Score: 663.3 bits (1710), Expect = 0.000e+0
Identity = 367/792 (46.34%), Postives = 499/792 (63.01%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEAR----HQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRH 2711
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK +YE L+ QC+ FA DLL QTR S EL  ILN               M   + E    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +      I   FP +S+ Y+++PKS+ G  +++PFIKF+CH  SY+ FL  L + +  +      N  +R   +GP P+  EW I+ ++ G+IW EIKQ++  G + Y+ D WNL+DF  N+LY A   L+I AY            R  WE + P L++E +FA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y +     CKG+                C  +   FS +FE +QSL+W+ FGLI L   N++ DH+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ IA+ +D EWKFAR++LW+S+FEEGGT P PFNIIPSPKS  Y I  +K  +F       RSK K     + +   +  R    +Q V+++L+KRY+    + A   +G+TE++  E+K DISSFR+E+I + K N   T A  +  + + + H
Sbjct:   25 AESELSTQEKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFAKDLLDQTRSSRELELILNFRDD-----------MNLLQDEANNELARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHI----VSNNPDR---QGPKPTTVEWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSGCK----PRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGI---------------RCERQNNAFSTLFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSICYLITWIKVHVF-----KRRSKRKETFGTLGRRAAENVRLNHQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVIGMMKGNRKSTRANKSDTSASDVSH 774

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Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEAR----HQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRH 2711
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK +YE L+ QC+ FA DLL QTR S EL  ILN               M   + E    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +      I   FP +S+ Y+++PKS+ G  +++PFIKF+CH  SY+ FL  L + +  +      N  +R   +GP P+  EW I+ ++ G+IW EIKQ++  G + Y+ D WNL+DF  N+LY A   L+I AY            R  WE + P L++E +FA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y +     CKG+                C  +   FS +FE +QSL+W+ FGLI L   N++ DH+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ IA+ +D EWKFAR++LW+S+FEEGGT P PFNIIPSPKS  Y I  +K  +F       RSK K     + +   +  R    +Q V+++L+KRY+    + A   +G+TE++  E+K DISSFR+E+I + K N   T A  +  + + + H
Sbjct:   25 AESELSTQEKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFAKDLLDQTRSSRELELILNFRDD-----------MNLLQDEANNELARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHI----VSNNPDR---QGPKPTTVEWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSGCK----PRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGI---------------RCERQNNAFSTLFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSICYLITWIKVHVF-----KRRSKRKETFGTLGRRAAENVRLNHQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVIGMMKGNRKSTRANKSDTSASDVSH 774

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Match: trpc5a (transient receptor potential cation channel, subfamily C, member 5a [Source:ZFIN;Acc:ZDB-GENE-040812-1])

HSP 1 Score: 656.366 bits (1692), Expect = 0.000e+0
Identity = 367/813 (45.14%), Postives = 513/813 (63.10%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEA---CKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSES----HNRSKWKSIRKLVKKVNEKEA-------RHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPA--YTTLRNVTKLRHKGSKKGFNR 2738
             E ELS +ER +L +VE+GD   V+  L     Y  ++ NC D LGR+AL IAIENE+ E++ELLL + +   D+LL+AI +E + AVE+LL+      +K+    ++    + FT DITP++LAAH +NY IIK+L+ R  TIP+PH +RC C ECV S + DSLRHSRSR+N Y+ALASPSLI LSS+DPILTAF L WEL  L  +ENEF+ +YE L++QC+ FA DLL Q R S EL TILNH   Q           E  +  E   L++LKLAIKY QK FV  P+CQQLL++LWY+G PG RR  +  +  +  +I   FP  S+ Y+L+PKS LG  +K+PFIKF+CH  SY+ FL  L + +  +           L  +GPPP++ EW I+ ++ G+IW EIK+++  G   Y+ D WNL+DF+ N+LY A   L+I AY     S      R+ WE + P LI+E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y  +  +    CKG+                C  +   FS +FE +QSL+W+ FGL++L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+F+EGGT P PFNIIPSPKS  Y    + H   C SE+     +  K +++++   K  EK A        +Q V++ L+KRY+    + A  ++G+TE++  E+K DISSFR+E++++  + N K P   Y++    T LR + S  G  R
Sbjct:   28 AEVELSPEERAFLSAVEKGDYAGVQHALREAEVYYNIDTNCVDPLGRSALLIAIENENLEVMELLLDHGVNTGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPSLMMDAQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKLFAKDLLDQARSSRELETILNHRDDQ----------SEELDPRECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWAVKLVMCFIIGLLFPVFSLVYLLAPKSTLGLFIKKPFIKFICHTASYLTFLFLLLLASQHIART-------NLHMQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVKYNSSR----PREEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETEAADEPNHCKGI---------------RCERQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFWYLCRWV-HGRLCGSETAPPEEDTHKHENLKEFTVKKAEKHADRLIQNQHYQEVIRSLVKRYVASMIRSAKTSEGLTEENFKELKQDISSFRYEVLDL--LGNRKPPRRNYSSSSEAT-LRDEVSDDGEAR 800

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Match: trpc5a (transient receptor potential cation channel, subfamily C, member 5a [Source:ZFIN;Acc:ZDB-GENE-040812-1])

HSP 1 Score: 655.21 bits (1689), Expect = 0.000e+0
Identity = 366/809 (45.24%), Postives = 510/809 (63.04%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEA---CKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEA-------RHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPA--YTTLRNVTKLRHKGSKKGFNR 2738
             E ELS +ER +L +VE+GD   V+  L     Y  ++ NC D LGR+AL IAIENE+ E++ELLL + +   D+LL+AI +E + AVE+LL+      +K+    ++    + FT DITP++LAAH +NY IIK+L+ R  TIP+PH +RC C ECV S + DSLRHSRSR+N Y+ALASPSLI LSS+DPILTAF L WEL  L  +ENEF+ +YE L++QC+ FA DLL Q R S EL TILNH   Q           E  +  E   L++LKLAIKY QK FV  P+CQQLL++LWY+G PG RR  +  +  +  +I   FP  S+ Y+L+PKS LG  +K+PFIKF+CH  SY+ FL  L + +  +           L  +GPPP++ EW I+ ++ G+IW EIK+++  G   Y+ D WNL+DF+ N+LY A   L+I AY     S      R+ WE + P LI+E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y  +  +    CKG+                C  +   FS +FE +QSL+W+ FGL++L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+F+EGGT P PFNIIPSPKS  Y    + H   C SE+    +     + +K+  EK A        +Q V++ L+KRY+    + A  ++G+TE++  E+K DISSFR+E++++  + N K P   Y++    T LR + S  G  R
Sbjct:   25 AEVELSPEERAFLSAVEKGDYAGVQHALREAEVYYNIDTNCVDPLGRSALLIAIENENLEVMELLLDHGVNTGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPSLMMDAQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKLFAKDLLDQARSSRELETILNHRDDQ----------SEELDPRECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWAVKLVMCFIIGLLFPVFSLVYLLAPKSTLGLFIKKPFIKFICHTASYLTFLFLLLLASQHIART-------NLHMQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVKYNSSR----PREEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETEAADEPNHCKGI---------------RCERQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFWYLCRWV-HGRLCGSETAPPEEDTHKHENLKEFTEKHADRLIQNQHYQEVIRSLVKRYVASMIRSAKTSEGLTEENFKELKQDISSFRYEVLDL--LGNRKPPRRNYSSSSEAT-LRDEVSDDGEAR 793

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Match: trpc5a (transient receptor potential cation channel, subfamily C, member 5a [Source:ZFIN;Acc:ZDB-GENE-040812-1])

HSP 1 Score: 655.21 bits (1689), Expect = 0.000e+0
Identity = 366/809 (45.24%), Postives = 510/809 (63.04%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEA---CKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEA-------RHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPA--YTTLRNVTKLRHKGSKKGFNR 2738
             E ELS +ER +L +VE+GD   V+  L     Y  ++ NC D LGR+AL IAIENE+ E++ELLL + +   D+LL+AI +E + AVE+LL+      +K+    ++    + FT DITP++LAAH +NY IIK+L+ R  TIP+PH +RC C ECV S + DSLRHSRSR+N Y+ALASPSLI LSS+DPILTAF L WEL  L  +ENEF+ +YE L++QC+ FA DLL Q R S EL TILNH   Q           E  +  E   L++LKLAIKY QK FV  P+CQQLL++LWY+G PG RR  +  +  +  +I   FP  S+ Y+L+PKS LG  +K+PFIKF+CH  SY+ FL  L + +  +           L  +GPPP++ EW I+ ++ G+IW EIK+++  G   Y+ D WNL+DF+ N+LY A   L+I AY     S      R+ WE + P LI+E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y  +  +    CKG+                C  +   FS +FE +QSL+W+ FGL++L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+F+EGGT P PFNIIPSPKS  Y    + H   C SE+    +     + +K+  EK A        +Q V++ L+KRY+    + A  ++G+TE++  E+K DISSFR+E++++  + N K P   Y++    T LR + S  G  R
Sbjct:   50 AEVELSPEERAFLSAVEKGDYAGVQHALREAEVYYNIDTNCVDPLGRSALLIAIENENLEVMELLLDHGVNTGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPSLMMDAQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKLFAKDLLDQARSSRELETILNHRDDQ----------SEELDPRECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWAVKLVMCFIIGLLFPVFSLVYLLAPKSTLGLFIKKPFIKFICHTASYLTFLFLLLLASQHIART-------NLHMQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVKYNSSR----PREEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETEAADEPNHCKGI---------------RCERQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFWYLCRWV-HGRLCGSETAPPEEDTHKHENLKEFTEKHADRLIQNQHYQEVIRSLVKRYVASMIRSAKTSEGLTEENFKELKQDISSFRYEVLDL--LGNRKPPRRNYSSSSEAT-LRDEVSDDGEAR 818

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Match: hint1 (histidine triad nucleotide binding protein 1 [Source:Xenbase;Acc:XB-GENE-1014427])

HSP 1 Score: 667.152 bits (1720), Expect = 0.000e+0
Identity = 366/775 (47.23%), Postives = 500/775 (64.52%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNH-DHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFY-SHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARH---QIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMN 2657
            +E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLSYN+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK L+ +G ++P+PH++RC C ECV     DSLRHSRSR+N YRAL+SPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+ D G +             +      L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  ++ +     ++   FPA S  Y+++PKS  G  +++PFIKF+CH  SY+ FL  L + +  +      N  E L  +GP P+I EW I+ ++ G+IW EIKQ++  G + Y+ D WNL+DF  N+LY A   L+I AY            R  WE + P L++E +FA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y +  +   CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFNIIPSPKS  Y I  ++  +  C +   R K +S   + ++  +   RH   Q VMK+L+KRY+    + A   +G+TE++  E+K DISSFRFE++ + K N
Sbjct:   25 SESELSPSEKAYLSAVEKGDYASVKQALEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSYNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKHLVQKGVSVPRPHEVRCNCVECVSGSDVDSLRHSRSRLNIYRALSSPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSSQCKQFAKDLLDQTRSSRELEIILNYRDDGGL------------LDDSNGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWVVKMVTCVIVGLLFPAFSCCYLIAPKSTFGLFIRKPFIKFICHTASYLTFLFLLLLASQNI------NKTESL--QGPAPTIVEWMILPWVLGFIWGEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKRN--------RAEWEMFHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEADAKSSDCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVDPKHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNIIPSPKSLWYLIKWIRKQI--CKKKMKR-KPESFGAIGRRAADNLRRHNHYQEVMKNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLKGN 753

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Match: TRPC5 (transient receptor potential cation channel, subfamily C, member 5 [Source:NCBI gene;Acc:100493720])

HSP 1 Score: 662.144 bits (1707), Expect = 0.000e+0
Identity = 359/799 (44.93%), Postives = 512/799 (64.08%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEA---CKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEA-------RHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHK 2714
             E ELS +E+ YL++VE+GD   VK  L+    Y  +NINC D LGR+AL IAIENE+ E++ELLLS+N+ + D+LL+AI +E + AVE+LL+      +K+    ++    + FT DITP++LAAH +NY IIK+L+ R  TIP+PH +RC C ECV S + DSLRHSRSR+N Y+ALASPSLI LSS+DPILTAF L WEL  L  +ENEFK +YE L++QC+KFA DLL Q R S EL  ILNH   Q           E  + ++   L++LK+AIKY QK FV  P+CQQLL++LWY+G PG RR  +  +      I   FP +S+ Y+++PKS+LG  +K+PFIKF+CH  SY+ FL  L + +  +           L  +GPPP++ EW I+ ++ G+IW EIK+++  G   Y+ D WNL+DF+ N+LY A   L+I AY     S      R+ W+ + P LI+E  FA +NILS ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y     E    CKG+                C  +   FS +FE +QSL+W+ FGL++L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+F+EG T P PFNII SPKS  YF   +++ L  C   ++    +   + +K   E+ A        +Q V+++L+KRY+    + +  N+G+TE++  E+K DISSFR+E++++  + N K P  +   + T++  K
Sbjct:   25 AEAELSQEEKAYLIAVEKGDYASVKHALEEAEIYYNININCMDPLGRSALLIAIENENLEIMELLLSHNIYVGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQRRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKKFAKDLLDQARSSRELEIILNHRDDQ----------SEELDPQKCHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWAVKLVTCITIGLLFPVLSVAYLIAPKSRLGLFIKKPFIKFICHTASYLTFLFLLLLASQHI-------VRTELHMQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFNEYVHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSKP----REEWDMWHPTLIAEAFFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETSASEEPNNCKGI---------------RCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGATMPPPFNIIASPKSIWYFCKWVRYKL--CPGKNSEEDIQKQHENLKTFTERHADNLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDL--LGNRKPPRRSYSTSSTEVSQK 783

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Match: TRPC1 (transient receptor potential cation channel, subfamily C, member 1 [Source:NCBI gene;Acc:100497011])

HSP 1 Score: 511.531 bits (1316), Expect = 6.484e-166
Identity = 303/791 (38.31%), Postives = 463/791 (58.53%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMA---TRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLL-WFYSHQRQEACKGVVFTYSITGQELERYQYCITRGR-YFSNIFEIIQSLYWTAFGL--IDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKS-CKYFILILKHCLFCCSESHNRSK-------WKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQ-RQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAY 2678
             +EE + DER +LL+ E+GD   VK +L+  +   LNIN  D LGR A+ I+IENE+ ++L+LLL+Y  +  D+LL AI  E + AV+ILL       TRP    L++ + N   + T D+ P+ILAAHR+NY I+ +LL +  ++PKPH + C C  C    K+DSLRHSR R++ YR LASP+LI L+ +DPIL AFELS +L  L ++E EF+ DYE LA++C+ FA DLLAQ R S EL  ILNH        S  P+  +    EE M LSRLKLAIKY QK FV   +CQQ L+++W+  + G RR     +  ++  +   +P +S+ Y+L+PKS++G I+  PF+KF+ H  SY  FLL      + +  +++    ++ +  GP     ++ +I++L G +W ++K+L+ +GL  +L +  N L F  N+LY A F L++ A+    +    + ERK W+A+ P L++E LFA  N+LS ++L FM+T +  LGPLQIS+G+ML+D   F  M++LVL ++  G+ QL    Y+   Q+ C G+               +C  +    F +      +L+W  F L  + L      +  +   F+G L++G+Y  + +I+L  + +AM++ S+Q+IA   DKEWKFAR++LW+S+F++  T P PFNI+PSPK+ C  F  I K    C   +  R K       WKS+R+      +++  +Q VM  L+ RYL   RQK       T ++LNE++ D+S FR E+ ++      K   +
Sbjct:   38 VKEETTLDERLFLLACEKGDYYMVKKLLEENSSEELNINSVDVLGRNAITISIENENLDILQLLLNYGCQSTDALLVAIDSEVVGAVDILLNHQPKWRTRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCTAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELAQKCKTFAKDLLAQARNSRELEVILNHQS------SDEPVD-KRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMAGYRRKHTCKKILIVLTVGIFWPVLSVCYLLAPKSQVGRIIHTPFMKFIIHGASYFTFLL-----LLNLYSLVYNE--DKKNTMGPALERIDFLLIMWLIGMVWSDVKRLWYDGLEDFLEESRNQLSFVMNSLYLATFALKVVAH----NKFHSIAERKDWDAFHPTLVAEGLFAFGNVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTTNEQKDCVGI---------------FCEQQSNDAFHSFTGTCYALFWYIFSLAHVALFVTRFSFSEELQSFVGALIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIVPSPKTICYLFNSISK--WICSHTTTGRVKRQNSLKEWKSLRQ------KRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEMRDLLGFRTSKYAMF 787

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Match: TRPC1 (transient receptor potential cation channel, subfamily C, member 1 [Source:NCBI gene;Acc:100497011])

HSP 1 Score: 511.146 bits (1315), Expect = 1.530e-165
Identity = 303/787 (38.50%), Postives = 462/787 (58.70%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMA---TRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLL-WFYSHQRQEACKGVVFTYSITGQELERYQYCITRGR-YFSNIFEIIQSLYWTAFGL--IDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKS-CKYFILILKHCLFCCSESHNRSK-------WKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQ-RQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMK 2666
             +EE + DER +LL+ E+GD   VK +L+  +   LNIN  D LGR A+ I+IENE+ ++L+LLL+Y  +  D+LL AI  E + AV+ILL       TRP    L++ + N   + T D+ P+ILAAHR+NY I+ +LL +  ++PKPH + C C  C    K+DSLRHSR R++ YR LASP+LI L+ +DPIL AFELS +L  L ++E EF+ DYE LA++C+ FA DLLAQ R S EL  ILNH        S  P+  +    EE M LSRLKLAIKY QK FV   +CQQ L+++W+  + G RR     +  ++  +   +P +S+ Y+L+PKS++G I+  PF+KF+ H  SY  FLL      + +  +++    ++ +  GP     ++ +I++L G +W ++K+L+ +GL  +L +  N L F  N+LY A F L++ A+    +    + ERK W+A+ P L++E LFA  N+LS ++L FM+T +  LGPLQIS+G+ML+D   F  M++LVL ++  G+ QL    Y+   Q+ C G+               +C  +    F +      +L+W  F L  + L      +  +   F+G L++G+Y  + +I+L  + +AM++ S+Q+IA   DKEWKFAR++LW+S+F++  T P PFNI+PSPK+ C  F  I K    C   +  R K       WKS+R+      +++  +Q VM  L+ RYL   RQK       T ++LNE++ D+S FR E+ ++      K
Sbjct:   58 VKEETTLDERLFLLACEKGDYYMVKKLLEENSSEELNINSVDVLGRNAITISIENENLDILQLLLNYGCQSTDALLVAIDSEVVGAVDILLNHQPKWRTRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCTAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELAQKCKTFAKDLLAQARNSRELEVILNHQS------SDEPVD-KRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMAGYRRKHTCKKILIVLTVGIFWPVLSVCYLLAPKSQVGRIIHTPFMKFIIHGASYFTFLL-----LLNLYSLVYNE--DKKNTMGPALERIDFLLIMWLIGMVWSDVKRLWYDGLEDFLEESRNQLSFVMNSLYLATFALKVVAH----NKFHSIAERKDWDAFHPTLVAEGLFAFGNVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTTNEQKDCVGI---------------FCEQQSNDAFHSFTGTCYALFWYIFSLAHVALFVTRFSFSEELQSFVGALIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIVPSPKTICYLFNSISK--WICSHTTTGRVKRQNSLKEWKSLRQ------KRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEMRDLLGFRTSK 803

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Match: TRPC1 (transient receptor potential cation channel, subfamily C, member 1 [Source:NCBI gene;Acc:100497011])

HSP 1 Score: 511.916 bits (1317), Expect = 7.425e-165
Identity = 303/787 (38.50%), Postives = 462/787 (58.70%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMA---TRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLL-WFYSHQRQEACKGVVFTYSITGQELERYQYCITRGR-YFSNIFEIIQSLYWTAFGL--IDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKS-CKYFILILKHCLFCCSESHNRSK-------WKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQ-RQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMK 2666
             +EE + DER +LL+ E+GD   VK +L+  +   LNIN  D LGR A+ I+IENE+ ++L+LLL+Y  +  D+LL AI  E + AV+ILL       TRP    L++ + N   + T D+ P+ILAAHR+NY I+ +LL +  ++PKPH + C C  C    K+DSLRHSR R++ YR LASP+LI L+ +DPIL AFELS +L  L ++E EF+ DYE LA++C+ FA DLLAQ R S EL  ILNH        S  P+  +    EE M LSRLKLAIKY QK FV   +CQQ L+++W+  + G RR     +  ++  +   +P +S+ Y+L+PKS++G I+  PF+KF+ H  SY  FLL      + +  +++    ++ +  GP     ++ +I++L G +W ++K+L+ +GL  +L +  N L F  N+LY A F L++ A+    +    + ERK W+A+ P L++E LFA  N+LS ++L FM+T +  LGPLQIS+G+ML+D   F  M++LVL ++  G+ QL    Y+   Q+ C G+               +C  +    F +      +L+W  F L  + L      +  +   F+G L++G+Y  + +I+L  + +AM++ S+Q+IA   DKEWKFAR++LW+S+F++  T P PFNI+PSPK+ C  F  I K    C   +  R K       WKS+R+      +++  +Q VM  L+ RYL   RQK       T ++LNE++ D+S FR E+ ++      K
Sbjct:  143 VKEETTLDERLFLLACEKGDYYMVKKLLEENSSEELNINSVDVLGRNAITISIENENLDILQLLLNYGCQSTDALLVAIDSEVVGAVDILLNHQPKWRTRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCTAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELAQKCKTFAKDLLAQARNSRELEVILNHQS------SDEPVD-KRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMAGYRRKHTCKKILIVLTVGIFWPVLSVCYLLAPKSQVGRIIHTPFMKFIIHGASYFTFLL-----LLNLYSLVYNE--DKKNTMGPALERIDFLLIMWLIGMVWSDVKRLWYDGLEDFLEESRNQLSFVMNSLYLATFALKVVAH----NKFHSIAERKDWDAFHPTLVAEGLFAFGNVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTTNEQKDCVGI---------------FCEQQSNDAFHSFTGTCYALFWYIFSLAHVALFVTRFSFSEELQSFVGALIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIVPSPKTICYLFNSISK--WICSHTTTGRVKRQNSLKEWKSLRQ------KRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEMRDLLGFRTSK 888

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Match: Trpc4 (transient receptor potential cation channel, subfamily C, member 4 [Source:MGI Symbol;Acc:MGI:109525])

HSP 1 Score: 671.389 bits (1731), Expect = 0.000e+0
Identity = 368/805 (45.71%), Postives = 516/805 (64.10%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFI-LILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARH---QIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIMRK 2750
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+     N++          E +    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +     +I   FP  S+ Y+++PKS LG  +++PFIKF+CH  SY+ FL  L + +  ++          L+ +GPPP+I EW I+ ++ G+IW EIKQ++  GL+ Y+ D WNL+DF  N+LY A   L+I A+         +  R+ W+ + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +  +CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFN+IPSPKS  Y +  I  H    C +   R K +S   + ++  +   RH   Q VM++L+KRY+    ++A   +G+TE+++ E+K DISSFRFE++ + + + + T       +      K   +G  +  RK
Sbjct:   25 AESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDD--NSL---------IEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-------RSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKY----SALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTH---LCKKKMRR-KPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLSTIQSANAASSADSDEKSQSEGNGKDKRK 788

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Match: Trpc4 (transient receptor potential cation channel, subfamily C, member 4 [Source:MGI Symbol;Acc:MGI:109525])

HSP 1 Score: 668.692 bits (1724), Expect = 0.000e+0
Identity = 364/778 (46.79%), Postives = 509/778 (65.42%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFI-LILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARH---QIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKT 2669
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+     N++          E +    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +     +I   FP  S+ Y+++PKS LG  +++PFIKF+CH  SY+ FL  L + +  ++          L+ +GPPP+I EW I+ ++ G+IW EIKQ++  GL+ Y+ D WNL+DF  N+LY A   L+I A+         +  R+ W+ + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +  +CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFN+IPSPKS  Y +  I  H    C +   R K +S   + ++  +   RH   Q VM++L+KRY+    ++A   +G+TE+++ E+K DISSFRFE++ + + + + T
Sbjct:   25 AESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDD--NSL---------IEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-------RSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKY----SALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTH---LCKKKMRR-KPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLST 761

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Match: Trpc5 (transient receptor potential cation channel, subfamily C, member 5 [Source:MGI Symbol;Acc:MGI:109524])

HSP 1 Score: 657.907 bits (1696), Expect = 0.000e+0
Identity = 352/783 (44.96%), Postives = 503/783 (64.24%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNH--DHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQ---RQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNE---KEARHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTP 2672
             E ELS +E+ +L +VE+GD   VK  L     Y  +NINC D LGR+AL IAIENE+ E++ELLL++++ + D+LL+AI +E + AVE+LL+      +K+    ++    + FT DITP++LAAH +NY IIK+L+ +  TIP+PH +RC C ECV S + DSLRHSRSR+N Y+ALASPSLI LSS+DPILTAF L WEL  L  +ENEFK +YE L++QC+ FA DLL Q R S EL  ILNH  DH             E  + ++   L++LK+AIKY QK FV  P+CQQLL++LWY+G PG RR  ++ +      I   FP +S+ Y++SP+S LG  +K+PFIKF+CH  SY+ FL  L + +  +           L  +GPPP++ EW I+ ++ G+IW EIK+++  G   Y+ D WNL+DF+ N+LY A   L+I AY     S      R+ WE + P LI+E LFA +NILS ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y  +       CKG+                C  +   FS +FE +QSL+W+ FGL++L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+F+EGGT P PFNIIPSPKS  Y      +      +   R +  ++R   ++  +   +   +Q V+++L+KRY+    + +  N+G+TE++  E+K DISSFR+E++++  + N K P
Sbjct:   25 AETELSAEEKAFLSAVEKGDYATVKQALQEAEIYYNVNINCMDPLGRSALLIAIENENLEIMELLLNHSVYVGDALLYAIRKEVVGAVELLLSYRKPSGEKQVPTLMMDTQFSEFTPDITPIMLAAHTNNYEIIKLLVQKRVTIPRPHQIRCNCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFKAEYEELSQQCKLFAKDLLDQARSSRELEIILNHRDDHS------------EELDPQKYHDLAKLKVAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRKHWVVKLLTCMTIGFLFPMLSIAYLISPRSNLGLFIKKPFIKFICHTASYLTFLFMLLLASQHI-------VRTDLHVQGPPPTVVEWMILPWVLGFIWGEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNGSR----PREEWEMWHPTLIAEALFAISNILSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETRAIDEPNNCKGI---------------RCEKQNNAFSTLFETLQSLFWSVFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSFLYLGNWFNNTFCPKRDPDGRRRRHNLRSFTERHADSLIQNQHYQEVIRNLVKRYVAAMIRNSKTNEGLTEENFKELKQDISSFRYEVLDL--LGNRKHP 767

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Match: Trpc1 (transient receptor potential cation channel, subfamily C, member 1 [Source:MGI Symbol;Acc:MGI:109528])

HSP 1 Score: 517.309 bits (1331), Expect = 4.189e-168
Identity = 306/784 (39.03%), Postives = 460/784 (58.67%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLT---AMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLL-WFYSHQRQEACKGVVFTYSITGQELERYQYCITRGR-YFSNIFEIIQSLYWTAFGL--IDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEK-EARHQIVMKDLIKRYLIQ-RQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAY 2678
             +EE + +E+ +LL+ ++GD   VK IL+  +   LNINC D LGR A+ I IENE  ++L+LLL Y  + AD+LL AI  E + AV+ILL      ++RP    L++ + N   + T D+ P+ILAAHR+NY I+ +LL +  ++PKPH + C C  C    K+DSLRHSR R++ YR LASP+LI L+ +DPIL AFELS +L  L ++E EF+ DYE LA QC+ FA DLLAQ R S EL  ILNH      T S  PL  +    EE M LSRLKLAIKY QK FV   +CQQ L+++W+  + G RR P   +   +  +   +P +S+ Y+++PKS+ G I+  PF+KF+ H  SY  FLL L + ++           ++ +  GP     ++ +I+++ G IW +IK+L+  GL  +L +  N L F  N+LY A F L++ A+    D  D    RK W+A+ P L++E LFA AN+LS ++L FM+T +  LGPLQIS+G+ML+D   F  M++LVL ++  G+ QL    Y+ + Q+ C G+               +C  +    F +      +L+W  F L  + +      Y  +   F+G +++G+Y  + +I+L  + +AM++ S+Q+IA   DKEWKFAR++LW+S+F++  T P PFNIIPSPK+  Y I  L   + C   S  + K ++  K  + + +K +  +Q VM  L+ RYL   RQK       T ++LNE++ D+S FR E+ ++      K   +
Sbjct:   56 VKEENTLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENESLDILQLLLDYGCQSADALLVAIDSEVVGAVDILLNHRPKRSSRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNH------TSSDEPLD-KRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYN-------EDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFAD----RKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGI---------------FCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWI-CSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMF 805

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Match: Trpc1 (transient receptor potential cation channel, subfamily C, member 1 [Source:MGI Symbol;Acc:MGI:109528])

HSP 1 Score: 488.804 bits (1257), Expect = 1.138e-157
Identity = 287/781 (36.75%), Postives = 439/781 (56.21%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLL-WFYSHQRQEACKGVVFTYSITGQELERYQYCITRGR-YFSNIFEIIQSLYWTAFGL--IDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEK-EARHQIVMKDLIKRYLIQ-RQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAY 2678
             +EE + +E+ +LL+ ++GD   VK IL+  +   LNINC D LGR A+ I I                            E+++ +++LL     +     L++ + N   + T D+ P+ILAAHR+NY I+ +LL +  ++PKPH + C C  C    K+DSLRHSR R++ YR LASP+LI L+ +DPIL AFELS +L  L ++E EF+ DYE LA QC+ FA DLLAQ R S EL  ILNH      T S  PL  +    EE M LSRLKLAIKY QK FV   +CQQ L+++W+  + G RR P   +   +  +   +P +S+ Y+++PKS+ G I+  PF+KF+ H  SY  FLL L + ++           ++ +  GP     ++ +I+++ G IW +IK+L+  GL  +L +  N L F  N+LY A F L++ A+    D  D    RK W+A+ P L++E LFA AN+LS ++L FM+T +  LGPLQIS+G+ML+D   F  M++LVL ++  G+ QL    Y+ + Q+ C G+               +C  +    F +      +L+W  F L  + +      Y  +   F+G +++G+Y  + +I+L  + +AM++ S+Q+IA   DKEWKFAR++LW+S+F++  T P PFNIIPSPK+  Y I  L   + C   S  + K ++  K  + + +K +  +Q VM  L+ RYL   RQK       T ++LNE++ D+S FR E+ ++      K   +
Sbjct:   56 VKEENTLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITI--------------------------ENESLDILQLLLDYGCQK-----LMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNH------TSSDEPLD-KRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYN-------EDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFAD----RKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGI---------------FCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWI-CSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMF 771

[Close]

BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Match: sp|Q9VJJ7|TRPG_DROME (Transient receptor potential-gamma protein OS=Drosophila melanogaster OX=7227 GN=Trpgamma PE=1 SV=2)

HSP 1 Score: 766.148 bits (1977), Expect = 0.000e+0
Identity = 399/822 (48.54%), Postives = 549/822 (66.79%), Query Frame = 3

Query:  363 ELSDDERKYLLSVERGDAPYVKSILDN-KNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTA--MATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFG----------NYVERL-SDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMK-----DSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIMRKTNL--PG 2765
            +L+ +E+K+LL+VERGD    + +L   ++   +N+NC D LGRTAL +AI+NE+ EM+ELL++YN++  D+LLH+ISEE +EAVE+LL    +    +     +     ++ FT DITPLILAAHRDNY IIKILLDRG  +P PHD+RC C ECV+S++EDSLRHSRSRINAYRALASPSLI LSSKDPILTAFELSWEL RL  LE+EFK +Y+ L +QCQ FAT LL  TR S EL  +LNHD          P+     E  E M L+RLKLAIK +QK FV H + QQLL+S+WYEGLPG RR     Q+  I  I   FP  S+ YIL+P S +G  +++PFIKF+CH  SY  FL  L + + ++E  + G          N +E L + RG  P+  EW I+ +++G IW E+KQL+  GL+ YL DMWN++DF TN+LY A   LR+ ++F ++     +S    + R+ W+A++P+LISE LF+AANI S +KLV++F++NP LGPLQ+SL RM+ DI+ FF +YVLVL A+  G++QLLW+Y+   ++ C  V    ++               R FSN+FE  Q+L+W  FGLIDL +  L+    FT F G LM G+Y  I+I++LLN+ IAMMN SYQ+I+E++D EWKFARS+LWIS+FEEGGT P PFNIIP+PKS  Y I  ++      S +  R   K+IR+  ++ ++++ ++Q +M++L++RY+   Q+  E+QGVTEDD+NEIK DIS+FR EL+EI K + M T    T         K +++   R+M+  N+  PG
Sbjct:   16 QLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNHD-------PTGPVY----EHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMIYNSHATDLPRERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDPNACIVWRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQDISAFRCELVEILKNSGMDT--NVTAGQGGGGGGKKNRQKERRLMKGFNIAPPG 824

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BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Match: sp|Q9QUQ5|TRPC4_MOUSE (Short transient receptor potential channel 4 OS=Mus musculus OX=10090 GN=Trpc4 PE=1 SV=1)

HSP 1 Score: 671.389 bits (1731), Expect = 0.000e+0
Identity = 368/805 (45.71%), Postives = 516/805 (64.10%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFI-LILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARH---QIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIMRK 2750
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+     N++          E +    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +     +I   FP  S+ Y+++PKS LG  +++PFIKF+CH  SY+ FL  L + +  ++          L+ +GPPP+I EW I+ ++ G+IW EIKQ++  GL+ Y+ D WNL+DF  N+LY A   L+I A+         +  R+ W+ + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +  +CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFN+IPSPKS  Y +  I  H    C +   R K +S   + ++  +   RH   Q VM++L+KRY+    ++A   +G+TE+++ E+K DISSFRFE++ + + + + T       +      K   +G  +  RK
Sbjct:   25 AESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDD--NSL---------IEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-------RSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKY----SALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTH---LCKKKMRR-KPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLSTIQSANAASSADSDEKSQSEGNGKDKRK 788

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BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Match: sp|P79100|TRPC4_BOVIN (Short transient receptor potential channel 4 OS=Bos taurus OX=9913 GN=TRPC4 PE=2 SV=2)

HSP 1 Score: 669.848 bits (1727), Expect = 0.000e+0
Identity = 364/778 (46.79%), Postives = 507/778 (65.17%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFI-LILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARH---QIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKT 2669
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+     N++          E +    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +     ++   FP  S+ Y+++PKS LG  +++PFIKF+CH  SY+ FL  L + +  ++          L+ +GPPP+I EW I+ ++ G+IW EIKQ++  GL+ Y+ D WNL+DF  N+LY A   L+I A+         +  R+ W+ + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +  +CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFN+IPSPKS  Y I  I  H    C +   R K +S   + ++  +   RH   Q VM++L+KRY+    + A   +G+TE++  E+K DISSFRFE++ + + + + T
Sbjct:   25 AESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDD--NSL---------LEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIVGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-------RSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKY----SALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH---LCKKKMRR-KPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761

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BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Match: sp|Q9UBN4|TRPC4_HUMAN (Short transient receptor potential channel 4 OS=Homo sapiens OX=9606 GN=TRPC4 PE=1 SV=1)

HSP 1 Score: 669.463 bits (1726), Expect = 0.000e+0
Identity = 365/778 (46.92%), Postives = 506/778 (65.04%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFI-LILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARH---QIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKT 2669
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+     N++          E +    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +     +I   FP  S+ Y+++PKS LG  +++PFIKF+CH  SY+ FL  L + +  ++          L+ +GPPP+I EW I+ ++ G+IW EIKQ++  GL+ Y+ D WNL+DF  N+LY A   L+I A+         +  R+ W+ + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +   CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFN+IPSPKS  Y I  I  H    C +   R K +S   + ++  +   RH   Q VM++L+KRY+    + A   +G+TE++  E+K DISSFRFE++ + + + + T
Sbjct:   25 AESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDD--NSL---------IEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-------RSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKY----SALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTH---LCKKKMRR-KPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLST 761

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BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Match: sp|O35119|TRPC4_RAT (Short transient receptor potential channel 4 OS=Rattus norvegicus OX=10116 GN=Trpc4 PE=1 SV=2)

HSP 1 Score: 668.307 bits (1723), Expect = 0.000e+0
Identity = 363/778 (46.66%), Postives = 509/778 (65.42%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFI-LILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARH---QIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKT 2669
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+ QC++FA DLL QTR S EL  ILN+     N++          E +    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +     +I   FP  S+ Y+++PKS LG  +++PFIKF+CH  SY+ FL  L + +  ++          L+ +GPPP+I EW I+ ++ G+IW EIKQ++  GL+ Y+ D WNL+DF  N+LY A   L+I A+         +  R+ W+ + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +  +CKG+                C  +   FS +FE +QSL+W+ FGLI+L   N++  H+FT+F+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+FEEGGT P PFN+IPSPKS  Y +  I  H    C +   R K +S   + ++  +   RH   Q VM++L+KRY+    ++A   +G+TE+++ E+K DISSFRFE++ + + + + T
Sbjct:   25 AESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNYRDD--NSL---------IEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHID-------RSDLNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKY----SALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTDFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTH---LCKKKMRR-KPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLST 761

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BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Match: A0A267FS73 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029366g3 PE=3 SV=1)

HSP 1 Score: 993.801 bits (2568), Expect = 0.000e+0
Identity = 479/790 (60.63%), Postives = 616/790 (77.97%), Query Frame = 3

Query:  363 ELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNS-SNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTD-RMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKK 2726
            +L+ +ER+YL +VE GD   V+  +++ +   +NINC DSLGR+ALH+AIE EH E+LE+LL+YNLE+ D+LLHAI EENI AVE+LL++   R KKKDL  LLG + S++FT D+TP+ILAA  DNY IIK+LLDRGD +PKPH+LRCAC +CV++ KEDSL+HS+SRINAY+ALASPSLI LSSKDPILTAFELSWE++RLG LE+EF+ +YE L+  CQKFAT LL QTR S ELA +LN D GQ N    + L  ++    E M L+RLK+AIKYKQK FV HPHCQQLL++LWYEGLPG RR     Q  +IG     FP +SM Y+++P+S+LG  +++PFIKF+CH  SYMLFL FL + A++VE ++     E++ +RG  PSI EW I+IY+ G++WQEIKQL+  G++AY+ DMWNLLDF TNALY A   LR  +Y+ +  +++ R + RKYW+AY+P LISECLFA ANI S++KLV +FTINP LGPLQISLGRML DIL F  + VLV+ ++A G +QL WFY++QR + C+   F + ITG +L++Y YC+TRGR FSN+FEI QSLYW+A+GLIDL+N +LEY+H FTEFIGKLM G++  I+ I+LLNM IAMMN S++ I  ++D EWKFAR +LWIS+F+EGGT P PFNIIPSPKS  Y +  LK  +  CS+ H RSKW+SIRK+VKKVNEKEAR+Q VM+DLIKRYL+ RQK+ + QGVTEDDLNEIKGDIS+FRFEL+EIF+ N M+TPA+   R+ TKLR +GSK+
Sbjct:   83 DLNMNERRYLQAVELGDLATVRRSIESASSLGININCRDSLGRSALHVAIEYEHIELLEVLLAYNLELGDALLHAIQEENIIAVEMLLSSQTERQKKKDLSGLLGTTPSSSFTPDVTPIILAAQIDNYEIIKLLLDRGDRVPKPHELRCACVDCVRAHKEDSLQHSKSRINAYKALASPSLIALSSKDPILTAFELSWEMHRLGRLEHEFREEYENLSADCQKFATALLEQTRSSEELAIVLNQDAGQGN----AKLNDKTLTEGERMNLARLKMAIKYKQKKFVAHPHCQQLLAALWYEGLPGFRRKHMFFQMGMIGTFAGIFPLLSMVYMVAPRSELGQKMRKPFIKFICHSASYMLFLGFLVLAAIRVEDLIMDTLEEKMQERGGAPSIVEWIIVIYILGFVWQEIKQLWGEGIKAYVTDMWNLLDFITNALYVATITLRGVSYYRVHQNSELRSLHRKYWDAYDPTLISECLFAIANIFSMLKLVNIFTINPHLGPLQISLGRMLNDILKFLFVVVLVICSFACGFNQLYWFYAYQRNKYCQDNKFYFGITGTDLDKYSYCVTRGRTFSNLFEITQSLYWSAYGLIDLSNTDLEYEHSFTEFIGKLMYGAFSAITFIVLLNMLIAMMNCSFEEIVAQADTEWKFARGKLWISYFDEGGTLPTPFNIIPSPKSFLYAMAWLKDKVCSCSKRHQRSKWQSIRKVVKKVNEKEARYQSVMRDLIKRYLMVRQKSDDKQGVTEDDLNEIKGDISAFRFELLEIFRTNGMRTPAHMQQRS-TKLRRRGSKR 867

[Close]

BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Match: A0A267DGY4 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig029366g2 PE=3 SV=1)

HSP 1 Score: 993.801 bits (2568), Expect = 0.000e+0
Identity = 479/790 (60.63%), Postives = 616/790 (77.97%), Query Frame = 3

Query:  363 ELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNS-SNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTD-RMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKK 2726
            +L+ +ER+YL +VE GD   V+  +++ +   +NINC DSLGR+ALH+AIE EH E+LE+LL+YNLE+ D+LLHAI EENI AVE+LL++   R KKKDL  LLG + S++FT D+TP+ILAA  DNY IIK+LLDRGD +PKPH+LRCAC +CV++ KEDSL+HS+SRINAY+ALASPSLI LSSKDPILTAFELSWE++RLG LE+EF+ +YE L+  CQKFAT LL QTR S ELA +LN D GQ N    + L  ++    E M L+RLK+AIKYKQK FV HPHCQQLL++LWYEGLPG RR     Q  +IG     FP +SM Y+++P+S+LG  +++PFIKF+CH  SYMLFL FL + A++VE ++     E++ +RG  PSI EW I+IY+ G++WQEIKQL+  G++AY+ DMWNLLDF TNALY A   LR  +Y+ +  +++ R + RKYW+AY+P LISECLFA ANI S++KLV +FTINP LGPLQISLGRML DIL F  + VLV+ ++A G +QL WFY++QR + C+   F + ITG +L++Y YC+TRGR FSN+FEI QSLYW+A+GLIDL+N +LEY+H FTEFIGKLM G++  I+ I+LLNM IAMMN S++ I  ++D EWKFAR +LWIS+F+EGGT P PFNIIPSPKS  Y +  LK  +  CS+ H RSKW+SIRK+VKKVNEKEAR+Q VM+DLIKRYL+ RQK+ + QGVTEDDLNEIKGDIS+FRFEL+EIF+ N M+TPA+   R+ TKLR +GSK+
Sbjct:   83 DLNMNERRYLQAVELGDLATVRRSIESASSLGININCRDSLGRSALHVAIEYEHIELLEVLLAYNLELGDALLHAIQEENIIAVEMLLSSQTERQKKKDLSGLLGTTPSSSFTPDVTPIILAAQIDNYEIIKLLLDRGDRVPKPHELRCACVDCVRAHKEDSLQHSKSRINAYKALASPSLIALSSKDPILTAFELSWEMHRLGRLEHEFREEYENLSADCQKFATALLEQTRSSEELAIVLNQDAGQGN----AKLNDKTLTEGERMNLARLKMAIKYKQKKFVAHPHCQQLLAALWYEGLPGFRRKHMFFQMGMIGTFAGIFPLLSMVYLVAPRSELGQKMRKPFIKFICHSASYMLFLGFLVLAAIRVEDLIMDTLEEKMQERGGAPSIVEWIIVIYILGFVWQEIKQLWGEGIKAYVTDMWNLLDFITNALYVATITLRGVSYYRVHQNSELRSLHRKYWDAYDPTLISECLFAIANIFSMLKLVNIFTINPHLGPLQISLGRMLNDILKFLFVVVLVICSFACGFNQLYWFYAYQRNKYCQDNKFYFGITGTDLDKYSYCVTRGRTFSNLFEITQSLYWSAYGLIDLSNTDLEYEHSFTEFIGKLMYGAFSAITFIVLLNMLIAMMNCSFEEIVAQADTEWKFARGKLWISYFDEGGTLPTPFNIIPSPKSFLYAMAWLKDKVCSCSKRHQRSKWQSIRKVVKKVNEKEARYQSVMRDLIKRYLMVRQKSDDKQGVTEDDLNEIKGDISAFRFELLEIFRTNGMRTPAHMQQRS-TKLRRRGSKR 867

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BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Match: A0A267F969 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013797g1 PE=3 SV=1)

HSP 1 Score: 984.171 bits (2543), Expect = 0.000e+0
Identity = 479/792 (60.48%), Postives = 610/792 (77.02%), Query Frame = 3

Query:  363 ELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYN-LEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLD--LLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMK-DSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKK 2726
            +L+ +ER+YLLSVE GD   V+  ++N     +N+NC DSLGR+A+ IAIE EH E+LE+LLS+  LE+ D+LLHAI EEN+ AVE+LL A A + +KK      +    S++FT DITP+ILAAH DNY I+KILLDRGD +PKPH+LRCAC ECV +QKEDSLRHS+SRINAY+ALASPSLICLSSKDPILTAFELSWE+ RLG LENEFK++YE LA +CQ++A+ LL QTR S+ELA +LN D GQ +   ++   +E  + EE MTLSRLKLAIKYKQK FV HPHCQQLL++LWY+GLPG RR   I Q  +I      FPA++  Y+L+P S++G  +++PFIKF+CH  SY+LFL FL + A++VE +LF     ++ +RG  PS  E  I+ Y+ G++WQEIKQL++ G +AY+ DMWNLLDF+TNALY A   LR  A++ ++ D     I R+YW+AY+P LISECLFA ANI S++KLV++FT+NP LGPLQISLGRML DIL F  + VLVL ++A G +QL WFY+++R + CK V   + ITG +LE+YQYC+TRGR FSN+FEI Q+LYW+ +GLIDL+N +LEY+H FTEF+GKLM G +  I+ ++LLNM IAMMN SY+ IA ++D EWKFARS+LWIS+FEEGGT PVPFNIIPSPKS  Y     K  L  CS+ H RSKW+SIRK+VK+VNE+EAR+Q VM+DL+KRYL+ RQ+  E QGVTEDDLNEIKGDIS+FRFEL+EI + N MKTPAYT  R  TKLR +GSK+
Sbjct:   68 DLNSNERRYLLSVEMGDMTSVRQYVENAETLSVNVNCVDSLGRSAVLIAIEFEHIELLEMLLSFGFLELGDALLHAIQEENVVAVEMLLHAQAEKQQKKPQAPGPMGAVPSSSFTPDITPIILAAHIDNYEILKILLDRGDRVPKPHELRCACDECVLAQKEDSLRHSKSRINAYKALASPSLICLSSKDPILTAFELSWEMKRLGRLENEFKSEYEQLAAKCQEYASALLEQTRSSAELAIVLNQDIGQ-SGHKVNEKALEETD-EERMTLSRLKLAIKYKQKKFVAHPHCQQLLAALWYDGLPGFRRKHLILQMGMIATFAGIFPALAFMYLLAPHSEMGQKMRKPFIKFICHSASYLLFLGFLVLAAIRVEDLLFDTMELKMKERGAGPSAVELIIVTYVMGFVWQEIKQLWNEGAKAYVTDMWNLLDFATNALYIATITLRGVAWYRVRQDGNLANIHRQYWDAYDPTLISECLFATANIFSMLKLVYIFTVNPHLGPLQISLGRMLSDILKFLFVVVLVLSSFACGFNQLYWFYAYERNKYCKDVKLGFGITGSDLEKYQYCVTRGRTFSNLFEITQTLYWSTYGLIDLSNTDLEYEHSFTEFVGKLMYGVFSAITFVVLLNMLIAMMNCSYESIATQADTEWKFARSKLWISYFEEGGTLPVPFNIIPSPKSFLYIATWTKERLCSCSKQHQRSKWQSIRKVVKRVNEREARYQTVMRDLVKRYLMVRQRLDERQGVTEDDLNEIKGDISAFRFELLEILRTNGMKTPAYTQHR-ATKLRRRGSKR 856

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BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Match: A0A267DBT5 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003128g1 PE=3 SV=1)

HSP 1 Score: 920.613 bits (2378), Expect = 0.000e+0
Identity = 444/739 (60.08%), Postives = 573/739 (77.54%), Query Frame = 3

Query:  363 ELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNS-SNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTD-RMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQ 2573
            +L+ +ER+YL +VE GD   V+  +++ +   +NINC DSLGR+ALH+AIE EH E+LE+LL+YNLE+ D+LLHAI EENI AVE+LL++   R KKKDL  LLG + S++FT D+TP+ILAA  DNY IIK+LLDRGD +PKPH+LRCAC +CV++ KEDSL+HS+SRINAY+ALASPSLI LSSKDPILTAFELSWE++RLG LE+EF+ +YE L+  CQKFAT LL QTR S ELA +LN D GQ N    + L  ++    E M LSRLK+AIKYKQK FV HPHCQQLL++LWYEGLPG RR     Q  +IG     FP +SM Y+++P+S+LG  +++PFIKF+CH  SYMLFL FL + A++VE ++     E++ +RG  PSI EW I+IY+ G++WQEIKQL+  G++AY+ DMWNLLDF TNALY A   LR  +Y+ +  +++ R + RKYW+AY+P LISECLFA ANI S++KLV +FTINP LGPLQISLGRML DIL F  + VLV+ ++A G +QL WFY++QR + C+   F + ITG +L++Y YC+TRGR FSN+FEI QSLYW+A+GLIDL+N +LEY+H FTEFIGKLM G++  I+ I+LLNM IAMMN S++ I  ++D EWKFAR +LWIS+F+EGGT P PFNIIPSPKS  Y +  LK  +  CS+ H RSKW+SIRK+VKKVNEKEAR+Q VM+DLIKRYL+ RQK+ +N+
Sbjct:   83 DLNMNERRYLQAVELGDLATVRRSIESASSLGININCRDSLGRSALHVAIEYEHIELLEVLLAYNLELGDALLHAIQEENIIAVEMLLSSQTERQKKKDLSGLLGTTPSSSFTPDVTPIILAAQIDNYEIIKLLLDRGDRVPKPHELRCACVDCVRAHKEDSLQHSKSRINAYKALASPSLIALSSKDPILTAFELSWEMHRLGRLEHEFREEYENLSADCQKFATALLEQTRSSEELAIVLNQDAGQGN----AKLNDKTLTEGERMNLSRLKMAIKYKQKKFVAHPHCQQLLAALWYEGLPGFRRKHMFFQMGMIGTFAGIFPLLSMVYLVAPRSELGQKMRKPFIKFICHSASYMLFLGFLVLAAIRVEDLIMDTLEEKMQERGGAPSIVEWIIVIYILGFVWQEIKQLWGEGIKAYVTDMWNLLDFITNALYVATITLRGVSYYRVHQNSELRSLHRKYWDAYDPTLISECLFAIANIFSMLKLVNIFTINPHLGPLQISLGRMLNDILKFLFVVVLVICSFACGFNQLYWFYAYQRNKYCQDNKFYFGITGTDLDKYSYCVTRGRTFSNLFEITQSLYWSAYGLIDLSNTDLEYEHSFTEFIGKLMYGAFSAITFIVLLNMLIAMMNCSFEEIVAQADTEWKFARGKLWISYFDEGGTLPTPFNIIPSPKSFLYAMAWLKDKVCSCSKRHQRSKWQSIRKVVKKVNEKEARYQSVMRDLIKRYLMVRQKSDDNE 817

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BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Match: A0A4Z2DCP6 (Transient receptor potential-gamma protein OS=Schistosoma japonicum OX=6182 GN=EWB00_002257 PE=4 SV=1)

HSP 1 Score: 902.123 bits (2330), Expect = 0.000e+0
Identity = 449/794 (56.55%), Postives = 591/794 (74.43%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSY-NLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGN-SSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHG-QVNTMSISPLRMESAESE---ETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTD-RMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLF--CCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLR 2708
            T  +L+D ER +L + E+GD   +K + D  N+  LN+NC D+LGR  L IAIENEH E+L+ L++  NL++ D +LHAI+E+N+ AVEI+L A   R  KKDL  LLG   S++FT DI  +ILAAHRDNY I+K+LLDRG+ I KPHDLRCAC+ C ++++E+ L+HS+ RIN YRAL SPS I L+S DPILTAFELSWEL +LG LENEF+TDY  L  +CQKFATD+LAQTR S EL+ ILNHD G  V+    S    + + SE   E M LSRLKLAI+Y+QK FV HPHCQQLL+++WYEGLPG R+ P   Q   IG++C+ FP ++ FY+L+P SK+GS++K+PFIKFLCH  SY+ FL  LT+ A +VEF+L  +  +R+ DRGP PS++E A++IY+ G++WQ++K+LY+ GLRAYL DMWNL+DF  NALY A   LR  A+  +    + R I R  W++++PVL+SECLFAAANI+S +KLV++FT++P+LGPLQISLGRML DI  FF +Y LVLVA+AFG +QL WFY+  R   CK V FT    GQ+ + Y YCITRG YF+N+FEI+QSLYW+A+GLIDLT+ NLEY H FTEF+GKL  G+Y YI+ I+LLNM IAMMN+SY+ I  + D EWKFARS+LWISFF EG T PVPFNIIP+PK+  Y +   +  LF  C  +  +R+ W+++R  +K+V E EAR+Q VM++L KRY++Q+ ++ EN  V+ DDL+EIKGDIS+FR EL++I K N MK PAY   + V+KLR
Sbjct:   12 TVGDLNDIERLFLYAAEQGDLATIKQLTDQANELKLNLNCTDTLGRDVLRIAIENEHMELLQFLVALPNLDLKDCILHAINEDNVIAVEIILHAQNERDVKKDLQGLLGRFQSSSFTPDINGIILAAHRDNYVILKLLLDRGERIYKPHDLRCACNICTQARRENGLQHSKLRINTYRALTSPSFIILTSNDPILTAFELSWELKKLGELENEFRTDYAELEAKCQKFATDMLAQTRSSVELSIILNHDTGADVSNCHFSGPNHQPSFSEDISERMQLSRLKLAIRYEQKQFVAHPHCQQLLATIWYEGLPGFRQKPVFAQLTTIGVLCSLFPLMATFYMLAPNSKMGSMMKKPFIKFLCHSSSYLSFLALLTLAATRVEFLLTNSLDQRMHDRGPTPSLTESALVIYVIGFVWQQMKKLYTCGLRAYLMDMWNLVDFVMNALYVATISLRTVAWARIVFYDEPRYINRGQWDSFDPVLVSECLFAAANIVSTLKLVYVFTVSPQLGPLQISLGRMLYDIFRFFCVYFLVLVAFAFGFNQLYWFYAKNRARNCKNVHFTLE-EGQK-DVYDYCITRGTYFTNLFEIVQSLYWSAYGLIDLTSFNLEYPHVFTEFVGKLTFGTYSYIAFIVLLNMLIAMMNSSYEQIVGQVDVEWKFARSKLWISFFGEGCTVPVPFNIIPTPKAFMYMLTSFQE-LFSNCYKKKLHRNDWEAVRLRIKQVKECEARYQSVMRELTKRYIMQKLRSSENDTVSADDLSEIKGDISAFRHELLDILKSNGMKIPAYH--KTVSKLR 800

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Match: trpc4b (short transient receptor potential channel 4-like [Source:NCBI gene;Acc:103045092])

HSP 1 Score: 668.307 bits (1723), Expect = 0.000e+0
Identity = 367/781 (46.99%), Postives = 504/781 (64.53%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNN--MKTPAYTT 2684
            +E ELS  E+ YL +VERGD   VK  LD    Y  +NINC D LGRTAL IAIENE+ E++ELLLSYN+ + D+LLHAI +E + AVE+LL       +K+    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N YRAL+SPSLI LSS+DP LTAF+LSWEL  L  +ENEFKT+YE L+ QC++FA DLL QTR S EL  ILN          +S L+ + + +E    L+RLKLAIKY+QK FV  P+CQQLL+S WY+  PG RR  +  +      I   FP +S+ Y+++PKS+ G  +++PFIKF+CH  SY+ FL  L + +  +          + + +GP P+  EW I+ ++ G+IW EIKQ++  G + Y+ D WNL+DF  N+LY A   L+I AY           +R  WE + P L++E +FA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y  +    CKG+                C  +   FS +FE +QSL+W+ FGLI L   N++ DH+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ IA+ +D EWKFAR++LW+S+FEEGGT P PFNIIPSPKS  Y I  +K  +F        +     R+  +KV     ++Q V+++L+KRY+    + A   +G+TE++  E+K DISSFR+E++ + K N   + TP  +T
Sbjct:   25 SEAELSCQEKAYLSAVERGDYGSVKRALDEAEIYFKININCVDPLGRTALLIAIENENLELIELLLSYNVHVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKLLVQKGVSVPQPHEVRCNCMECVSSSDVDSLRHSRSRLNIYRALSSPSLIALSSEDPFLTAFQLSWELQELSKVENEFKTEYEELSHQCKRFAKDLLDQTRSSRELELILNFRD------DLSLLQDQESNNE----LARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKFITCVFIGLLFPTLSICYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHI-------VSTKPNLQGPAPTTVEWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYSGYK----QRDKWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYDTKDDRVCKGI---------------RCEHQNNAFSTLFETLQSLFWSIFGLIGLYVTNVQADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPTPFNIIPSPKSIWYLITWIKIHVFRRKSKRTETFGVLGRRAAEKVRLNN-QYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVLGMMKGNRTCLPTPKLST 768

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Match: trpc5a (short transient receptor potential channel 5-like [Source:NCBI gene;Acc:103044006])

HSP 1 Score: 664.84 bits (1714), Expect = 0.000e+0
Identity = 362/802 (45.14%), Postives = 513/802 (63.97%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEA---CKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEK---EARHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTP--AYTTLRNVTKLRHKGSKKG 2729
             E ELS +ER +LL+VE+GD   VK  L     Y  +++NC D LGR+AL IAIENE+ E++ELLL + +   D+LL+AI +E + AVE+LL+      +K+    ++    + FT DITP++LAAH +NY IIK+L+    TIP+PH +RC C ECV S + DSLRHSRSR+N Y+ALASPSLI LSS+DPILTAF L WEL  L  +ENEF+ +YE L++QC++FA DLL Q R S EL TILNH   Q           E  +  E   L++LKLAIKY QK FV  P+CQQLL++LWY+G PG RR  +  +  +  +I   FP  S+ Y+L+P+S LG  +K+PFIKF+CH  SY+ FL  L + +  +           L  +GPPP++ EW I+ ++ G+IW EIK+++  G   Y+ D WNL+DF+ N+LY A   L++ AY     S      R+ WE + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y  Q  +    CKG+                C  +   FS +FE +QSL+W+ FGL++L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+F+EGGT P PFNI+PSPKS  Y    L   L    ++ +  K ++++ L +K  ++      +Q V++ L+KRY+    + A  N+G+TE++  E+K DISSFR+E++++  + N K P   Y++    T LR +GS  G
Sbjct:   28 AEVELSQEERAFLLAVEKGDYAGVKHALQEAEVYYNIDVNCVDPLGRSALLIAIENENLEVMELLLDHGVNTGDALLYAIRKEVVGAVELLLSHRRPSGEKQVPSLMMDAQFSEFTPDITPIMLAAHTNNYEIIKLLVQHKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKRFAKDLLDQARSSRELETILNHRDDQS----------EELDPRECRDLAKLKLAIKYHQKEFVSQPNCQQLLATLWYDGFPGWRRRHWAVKLVMCIIIGLLFPVFSIIYLLAPRSSLGFFIKKPFIKFICHTASYLTFLFLLLLASQHIART-------NLHMQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFTEYVHDWWNLMDFAMNSLYLATISLKMVAYVKYNSSR----PREEWEMWHPTLMAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETQAADEPNHCKGI---------------RCEKQNNAFSTLFETLQSLFWSIFGLLNLYVTNVKARHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIVPSPKSAWYLCCWLHRWLCWRGDAPHSEKHENLKDLTEKHADRIIQNKHYQEVIRSLVKRYVAAMIRSAKTNEGLTEENFKELKQDISSFRYEVMDL--LGNRKPPRRTYSSSSEAT-LRDEGSDDG 790

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Match: trpc4a (short transient receptor potential channel 4-like [Source:NCBI gene;Acc:103035222])

HSP 1 Score: 657.907 bits (1696), Expect = 0.000e+0
Identity = 359/773 (46.44%), Postives = 497/773 (64.29%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFY---SHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMN 2657
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC D LGRTAL IAIENE+ E++ELLLS+N+ + D+LLHAI +E + AVE+LL     R   +    LL    + FT DITP+ILAAH +NY IIK+L+ +G ++P+PH++RC C ECV S   DSLRHSRSR+N YRAL+SPSLI LSS+DP LTAF LSWEL  L  +ENEFK +YE L++QC++FA +LL QTR S EL  ILN+         I+PL     E E    L+RLKLA++Y QK FV  P+CQQLL+S WY+  PG RR  +  +      I   FP  S+FY+++PKS  G  +++PFIKF+CH  SY+ FL  L + +  +          +   +GPPP+  EW I+ ++ G+IW EIKQ++  G + Y+ D WNL+DF  N+LY A   L++ AY     S      R+ W+ + P L++E +FA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   +    + CKG+                C  +   F+ +FE +QSL+W+ FGLIDL   N+  DH+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ IA+ +D EWKFAR++LW+S+FEEGGT P PFNIIPSPKS  YF+  +K  +F  + +   +     R+  + V     ++Q V+++L+KRY+    + A   +G+TE++  E+K DISSFR+E++ + K N
Sbjct:   25 AESELSPLEKAYLNAVEKGDYASVKQSLEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHKKQRGGMQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKLLVQKGVSMPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYRALSSPSLIALSSEDPFLTAFRLSWELEELSKVENEFKYEYEELSQQCKQFAKNLLDQTRSSRELELILNYRD------DINPL-----EDEGVNDLARLKLAVRYHQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKFITCIFIGLLFPLFSIFYLVAPKSHYGLFIRKPFIKFICHTASYLTFLFLLLLASQHIT-------GSKALSQGPPPNTVEWMILPWVLGFIWAEIKQMWDGGFQDYVHDWWNLMDFVMNSLYLATISLKVVAYLKYSGSN----ARESWDMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETDASNSTKWCKGI---------------RCEHQNNAFTTLFETLQSLFWSIFGLIDLHVTNVGPDHRFTEFVGATMFGTYNIISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSVWYFVRWIKRNVFRVAATKTETFGTISRRAAENVRINH-QYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVMGMMKGN 759

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Match: trpc5b (transient receptor potential cation channel, subfamily C, member 5b [Source:ZFIN;Acc:ZDB-GENE-091112-24])

HSP 1 Score: 577.015 bits (1486), Expect = 0.000e+0
Identity = 347/787 (44.09%), Postives = 476/787 (60.48%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNH--DHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEA---CKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEA--RHQIVMKDLIKRY---LIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYT 2681
             E ELS +ER YL +VE+GD   VK  L     Y  +NINC D LGR+AL IAIENE+ E++ELLLS+ +++ D+LL+AI +E + AVE+LL+      +K+    ++ +  + FT DITP++LAAH +NY IIK+L+ R  TIP+PH +RC C ECV S + DSLRHSRSR+N Y+ LASPSLI LSS+DPILTAF L WEL  L  +ENEF+ +YE L++QC+ FA DLL Q R S EL TILNH  DH             E  +  E   L++LKLAIKY QK FV  P+CQQLL++LWY+G PG RR  ++ +      I   FP  S+ Y+L+PKS LG  +K+PFIKF+CH  SY+ FL  L + +  +           L  +GPPP+I EW I+ ++ G+IW EIK+++  G   Y+ D WNL+DF+ N+LY A   L++ AY     S      R+ WE + P LI+E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y  +  +    CKG+                C  +   FS  F II  L  T F L  L +        F +    L        SI M +  FIAM     Q   + +D EWKFAR++LW+S+F+EGGT P PFNIIPSPKS  Y  + L   L  C     R + +   + +K+   K    R++++ ++L+KRY   +I+R K  E  G+TE++  E+K DISSFR+E++++  + N K P  T
Sbjct:   25 AEAELSAEERAYLTAVEKGDYAGVKMALQEAEIYYNININCLDPLGRSALLIAIENENLEVMELLLSHGVQVGDALLYAIRKEVVGAVELLLSHRKPSGEKQVPALMMDSQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKTLASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKLFAKDLLDQARSSRELETILNHRDDHS------------EELDPRECRDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRRHWVVKLVTCFTIGLLFPVFSIIYLLAPKSALGFFIKKPFIKFICHTASYLTFLFLLLLASQHI-------VRTDLHVQGPPPTIVEWMILPWVLGFIWAEIKEMWDGGFTEYVHDWWNLMDFAMNSLYLATISLKMVAYLKYNSSRP----REEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETEAADEPNHCKGI---------------RCEKQNNAFST-FIIITFL--TVFALTALED-------TFKDLKIPL--------SIAMFITRFIAMFPLPPQ---DHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSVWYLCVWLHSRL--CGRGQPRQEEEHKHENLKEFTVKTVLLRNEVI-RNLVKRYVAAMIRRTKTDE--GLTEENFKELKQDISSFRYEVLDL--LGNRKPPRRT 745

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Match: trpc1 (transient receptor potential cation channel subfamily C member 1 [Source:NCBI gene;Acc:103046331])

HSP 1 Score: 487.649 bits (1254), Expect = 5.156e-157
Identity = 287/777 (36.94%), Postives = 456/777 (58.69%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLT---AMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGL--IDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQ-RQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMK 2666
             +E+ + DE+ +LL+ E+GD   VK +L+ K    LN+NC D LGR A+ IAIENE+ ++L+LLL +  +  D+LL AI  E + AV+ILL      +++P    L+  + N   + T D+ P+ILAAHR+NY I+ +LL +  ++P+PH + C C  C    K+DSLRHSR R++ YR LASPSLI L+ +DPIL AFELS +L  L ++E EF+ DYE LA+QC+ FA DLLAQ R S EL  ILNH   + +      L       EE M LSRLKLAIKY QK FV   +CQQ L+++W+  +   RR     +   +  +   +P +S+ Y+L P+S++G I+  PF+KF+ H  SY  FLL      + +  +++    ++ +  GP   + ++ +I+++ G +W ++K+L+  GL  +L +  N L F  N+LY A F L++ A+   K+  +   ERK W+A  P+L++E LFA AN+LS ++L FM+T +  LGPLQIS+G+ML++   F  +++LVL ++  G+ QL   Y   +++   G   T     +E E     +     F +      +L+W  F L  + L    + Y  +   F+G +++G+Y  + +I+L  + +AM++ S++ IA   DKEWKFAR++LW+S+F++  T P PFNI+PSPK+  Y +  L   +   + +    +  S+R+      + +  +Q +M  L+ RYL   RQK       T ++LN+++ D+S FR E+ ++      K
Sbjct:   38 VKEDTTLDEKLFLLACEKGDYYMVKKLLEEKRHGELNLNCVDVLGRDAVTIAIENENLDILQLLLEHGCQSTDALLVAIDSEVVGAVDILLNHRPRRSSKPSIAKLMQRIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDISLPRPHAVGCECTLCNAKNKKDSLRHSRFRLDIYRCLASPSLIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELAKQCKMFAKDLLAQARNSRELEVILNHTSSEDHVDKRGLL-------EERMNLSRLKLAIKYNQKEFVAQSNCQQFLNTVWFGEMASYRRKHTGLKMGTVLSVALLWPLLSVCYLLGPRSRVGQIIHTPFVKFIIHSASYFTFLL-----LLNLYSLVYNE--DKKNTMGPALEMIDYLLILWIIGMVWSDVKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHSKFKNVDE--TERKNWDASNPILVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQEFGKFLGLFLLVLFSFTIGLTQL---YGKDKKDTTTGKNGT-----EECEGINCPLQSNDTFHSFMGTCYALFWYIFSLAHVALYVTRITYTDELRSFVGAMIVGTYNIVVVIVLTKLLVAMLHKSFRQIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNILPSPKTLCYLVTSLSKWICSHTSTGKVKRQNSLREWRNLKQKHDENYQKIMCCLVHRYLTSTRQKMQSTDQATVENLNDLRQDLSKFRNEMRDLLGFRTSK 790

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Match: trpc4b (transient receptor potential cation channel, subfamily C, member 4b [Source:ZFIN;Acc:ZDB-GENE-120329-1])

HSP 1 Score: 452.21 bits (1162), Expect = 2.735e-147
Identity = 247/589 (41.94%), Postives = 351/589 (59.59%), Query Frame = 3

Query:  675 GNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICAS----FPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFY---SHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCL 2420
            G+SS  FT D+TP+ILAAH +NY +IK+LL RG ++P+PH +RCAC +C    + D LRHSRSR+  YRALASP L+ L+S+DP LTAF LS EL  L  +ENEFK +YE L++QC++FA +LL QTR + EL  +LN+                + E+ +   L RLKLAIKY QK FV  P+CQQLL+SLWY+G PG RR       AV  + CA+    FP  S+ Y+L+P+S++   L++PFIKF+CH  SY+ FL  L + + ++            + +GP P++ EW I+ ++   IW EIKQ++  G   Y+ D WNL+DF  N+LY A   L++ AY     S      R+ WE + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   + Q  + CKG+                C  +   FS +   ++ L+ +    + L        H FT       L  Y  I + +  ++ I   N +++   + +D EWKFAR++LW+S+FEEG T P PFNI+PSPKS  Y    ++ C+
Sbjct:    9 GHSSE-FTPDMTPIILAAHTNNYELIKLLLTRGVSVPRPHAVRCACLQCAAGSEADGLRHSRSRLAVYRALASPCLVALASEDPFLTAFTLSCELCELSRVENEFKAEYEELSQQCKQFAKELLDQTRSTRELEIVLNYKEESDG----------APEAPDAFNLERLKLAIKYHQKEFVAQPNCQQLLASLWYDGFPGWRR----RHWAVKLVTCATLGLLFPLFSVCYLLAPRSRMAFFLRKPFIKFICHTASYLTFLFLLLLASQQIA-------RTDPNMQGPSPTLVEWMILPWICRLIWAEIKQMWDGGFSEYVHDWWNLMDFVMNSLYLATISLKLVAYLKYSGSK----AREQWEMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETSAGQGNDTCKGI---------------RCEKQNNAFSTLCNCLKHLFPSVSICVHLCPSGSICFHLFTSVSICFHLFPYVSICVHLFPSVSITSCN-AFKNTVDHADIEWKFARTKLWMSYFEEGATLPPPFNIVPSPKSAWYLCRYVRACI 555

[Close]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Match: trpc4b (transient receptor potential cation channel, subfamily C, member 4b [Source:ZFIN;Acc:ZDB-GENE-120329-1])

HSP 1 Score: 439.884 bits (1130), Expect = 9.405e-143
Identity = 241/591 (40.78%), Postives = 341/591 (57.70%), Query Frame = 3

Query:  696 TSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICAS----FPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFY---SHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLE---------YDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCL 2420
            T D+TP+ILAAH +NY +IK+LL RG ++P+PH +RCAC +C    + D LRHSRSR+  YRALASP L+ L+S+DP LTAF LS EL  L  +ENEFK +YE L++QC++FA +LL QTR + EL  +LN+                + E+ +   L RLKLAIKY QK FV  P+CQQLL+SLWY+G PG RR       AV  + CA+    FP  S+ Y+L+P+S++   L++PFIKF+CH  SY+ FL  L + + ++            + +GP P++ EW I+ ++   IW EIKQ++  G   Y+ D WNL+DF  N+LY A   L++ AY     S      R+ WE + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y   + Q  + CKG+                C  +   FS  F  +       F L    ++ +          Y  +    +    L    + S I+     I    +    + + +D EWKFAR++LW+S+FEEG T P PFNI+PSPKS  Y    ++ C+
Sbjct:    1 TPDMTPIILAAHTNNYELIKLLLTRGVSVPRPHAVRCACLQCAAGSEADGLRHSRSRLAVYRALASPCLVALASEDPFLTAFTLSCELCELSRVENEFKAEYEELSQQCKQFAKELLDQTRSTRELEIVLNYKEESDG----------APEAPDAFNLERLKLAIKYHQKEFVAQPNCQQLLASLWYDGFPGWRR----RHWAVKLVTCATLGLLFPLFSVCYLLAPRSRMAFFLRKPFIKFICHTASYLTFLFLLLLASQQIA-------RTDPNMQGPSPTLVEWMILPWICRLIWAEIKQMWDGGFSEYVHDWWNLMDFVMNSLYLATISLKLVAYLKYSGSK----AREQWEMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETSAGQGNDTCKGI---------------RCEKQNNAFSTWFTSVS----ICFHLFPYVSICVHLFPSVSIFFYTDKRKNMLNAAYLREMHFSSAIVACQTIIRASASDPNHVEDHADIEWKFARTKLWMSYFEEGATLPPPFNIVPSPKSAWYLCRYVRACI 547

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Match: trpc3 (transient receptor potential cation channel, subfamily C, member 3 [Source:ZFIN;Acc:ZDB-GENE-140129-1])

HSP 1 Score: 405.216 bits (1040), Expect = 2.177e-126
Identity = 273/827 (33.01%), Postives = 418/827 (50.54%), Query Frame = 3

Query:  366 LSDDERKYLLSVERGDAPYVKSIL-DNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNL--EIADSLLHAISEENIEAVEILLTAMATRPKKKDLL----------DLLGNSSNA--FTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAM-KVEFI-LFGNYVER------LSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIE----------------------RKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKS---------------CKY----FILILKHCLFCCSESHNRSKWKSIR----KLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIE 2642
            L+ +E ++L + E G+ P V+ +L D      LN+NC D +G+ A+ +A+ NEH E+ ELLL  +    + D+L+ AIS+  +  VE +L   A   +K+ +L          D      +   F+ DITP+ILAAH   Y I+ ILL RG  I +PHD  C C EC + Q+ D+  HSRSRINAYR LASP+ + LSS+DP+LTA ELS EL  L  +E EFK DY+ L+ QC+ F   LL   R + E+  ILN D        ++P     A   +   L RLKLAIKY+ K                                  IG +  S                      PF+KF+ H  S+ +FL  L + A  + E + L  N  E          +    + +E  I+ ++ G IW E K+L++ GL+ YL  +WN+LDF   +++ A+F  R+ A+    ++  R ++                      R +W   +P +ISE L++ A +LS  ++ ++   N   GPLQISLG+ ++DI  F  ++++V +A+  G+  L   YS+ R                            R F  + E  ++L+W+ FGL ++ ++ + Y+H+F E IG ++ G Y    +++LLNM IAM+N+SYQ I + SD EWKFAR++LWIS+FE+G T PVPFN++PSPKS               C++      L ++  +       N    +++R    + +  + +   R+Q +MK LIKRY+++ Q   EN  V E +L +IK DISS R+EL+E
Sbjct:   37 LTAEEERFLDAAEYGNIPVVRRMLEDGGAGRSLNVNCVDYMGQNAMQLAVGNEHLEVAELLLKRDKLSRVGDALMLAISKGYVRIVEAILAHPAFAGEKRLILSPREQETQDDDFYAYDEDGTRFSPDITPIILAAHCQEYEIVHILLRRGARIERPHDYFCKCGECTEKQRHDAFSHSRSRINAYRGLASPAYLSLSSEDPVLTALELSNELAMLANIEKEFKNDYKKLSVQCKDFVVGLLDLCRDTEEVEAILNGD------AELNP----PACDRQRAALIRLKLAIKYEVKK---------------------------------IGKVLRS----------------------PFMKFVAHAASFTIFLALLVLNASDRFEGVKLLPNETETDHPQQLFRIKTTSFTWTELLIVAWIIGMIWAECKELWAEGLKEYLFQLWNVLDFGMLSIFVASFTARLFAFLKASEA-QRFVDSEGFPNVSNATLPEHIRYFNLARSHWLPSDPQIISEGLYSIAIVLSFSRIAYILPANESFGPLQISLGQTVKDIFKFMVIFIMVFLAFMIGMFNL---YSYYRGAKV-----------------------NRAFVTVEESFKTLFWSIFGLSEVASVVINYNHKFIENIGYILYGVYNVTMVVVLLNMLIAMINSSYQEIEDDSDVEWKFARAKLWISYFEQGRTLPVPFNLVPSPKSAVQLLLAAARALGRLCRWRKHKGKLDVEMDMLDAKAKPNTLTQRALRSNMNRSMNSIGQHPTRYQQIMKRLIKRYVLKAQFDKENDEVNEGELKDIKQDISSLRYELLE 771

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007332.1 (pep scaffold:Pmarinus_7.0:GL483392:1130:9476:1 gene:ENSPMAG00000006613.1 transcript:ENSPMAT00000007332.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 82.4185 bits (202), Expect = 2.825e-16
Identity = 141/609 (23.15%), Postives = 230/609 (37.77%), Query Frame = 3

Query:  636 ATRPKKKDLLDLLGNSSNAFTSD---ITPLILAAHRDNYPIIKILLDRGDT-IPKPHDLRCACHECVKSQKEDSL----RHSRSRINAYRALASPSLIC-------------LSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGL------PGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGS--YMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMW-NLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNL-NLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNII 2369
            AT    + L  LLG  ++   +D    TPL +AA     P ++ LL+ G     +  D R A            L    RHS              ++C             L +  P+  A +L+       + E E   D ++ A  CQ  ATDLL+   GS                 S     +  A  E  ++L  L + I+  Q++   HP  Q  LS +W  GL      P +  L F        L+C   P + + + L    +   I   P IKFLCH  S  ++L L  LT+    +  I  G+ +         PS +EW ++ +L G +  E++Q    G R  LA  W  LL    + L   A    ++A      S   +         E +     L A A     ++L+   + +   GP  I +  +++D+  F  +  +  VA+   +  L           C+ V       G                    ++   L+++ FG+ D  +L ++         +     G Y  +++I+L+N+ IAMM+ +YQ I  +SD +WKF R  L +       T P P N++
Sbjct:   81 ATAGHVETLRLLLGQGADINATDKSGCTPLHVAARAGRLPAVRALLESGAVGSAECRDGRTALEHAAGGGHRHVLALLLRHSTLTAQRLIHFVYDLMVCGRQCEFRVIDEFVLLAPAPLEAAVKLTRAFGAAALREKERSVDLDLAARHCQALATDLLSLAVGSQ----------------SAGAAALLQAVDERGLSL--LDVLIECHQRAVAAHPAVQHHLSDVWRGGLRWPSWCPALLLLGF--------LVC---PPLWVAFSLPLGHRFTRI---PIIKFLCHLASHLFLLSLFVLTVVWPPITPIAEGHLL---------PSWNEWLLLTWLLGLLLAELRQ---GGSRFGLA--WIRLLVLGLSGL---ALLCHLSALAFPAGSHALL---------ECLCARNVLLAKALAFCCVQLLDFLSFHHLFGPWAIIISDLMKDLARFGMVLGIFHVAFTLHLTAL-----------CQPVYPQGDPVGNS-STAAAAWDPSTAAQTTLDVTVLLFFSLFGMGDQNSLPDVSRSPSIVSTLVNATFGVYLIVTLIVLINLLIAMMSDTYQRIQAQSDTQWKFGRVVL-VREATRRTTPPAPLNVV 618

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007334.1 (pep scaffold:Pmarinus_7.0:GL483392:1130:8888:1 gene:ENSPMAG00000006613.1 transcript:ENSPMAT00000007334.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 82.4185 bits (202), Expect = 3.400e-16
Identity = 141/609 (23.15%), Postives = 230/609 (37.77%), Query Frame = 3

Query:  636 ATRPKKKDLLDLLGNSSNAFTSD---ITPLILAAHRDNYPIIKILLDRGDT-IPKPHDLRCACHECVKSQKEDSL----RHSRSRINAYRALASPSLIC-------------LSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGL------PGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGS--YMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMW-NLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNL-NLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNII 2369
            AT    + L  LLG  ++   +D    TPL +AA     P ++ LL+ G     +  D R A            L    RHS              ++C             L +  P+  A +L+       + E E   D ++ A  CQ  ATDLL+   GS                 S     +  A  E  ++L  L + I+  Q++   HP  Q  LS +W  GL      P +  L F        L+C   P + + + L    +   I   P IKFLCH  S  ++L L  LT+    +  I  G+ +         PS +EW ++ +L G +  E++Q    G R  LA  W  LL    + L   A    ++A      S   +         E +     L A A     ++L+   + +   GP  I +  +++D+  F  +  +  VA+   +  L           C+ V       G                    ++   L+++ FG+ D  +L ++         +     G Y  +++I+L+N+ IAMM+ +YQ I  +SD +WKF R  L +       T P P N++
Sbjct:   81 ATAGHVETLRLLLGQGADINATDKSGCTPLHVAARAGRLPAVRALLESGAVGSAECRDGRTALEHAAGGGHRHVLALLLRHSTLTAQRLIHFVYDLMVCGRQCEFRVIDEFVLLAPAPLEAAVKLTRAFGAAALREKERSVDLDLAARHCQALATDLLSLAVGSQ----------------SAGAAALLQAVDERGLSL--LDVLIECHQRAVAAHPAVQHHLSDVWRGGLRWPSWCPALLLLGF--------LVC---PPLWVAFSLPLGHRFTRI---PIIKFLCHLASHLFLLSLFVLTVVWPPITPIAEGHLL---------PSWNEWLLLTWLLGLLLAELRQ---GGSRFGLA--WIRLLVLGLSGL---ALLCHLSALAFPAGSHALL---------ECLCARNVLLAKALAFCCVQLLDFLSFHHLFGPWAIIISDLMKDLARFGMVLGIFHVAFTLHLTAL-----------CQPVYPQGDPVGNS-STAAAAWDPSTAAQTTLDVTVLLFFSLFGMGDQNSLPDVSRSPSIVSTLVNATFGVYLIVTLIVLINLLIAMMSDTYQRIQAQSDTQWKFGRVVL-VREATRRTTPPAPLNVV 618

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Match: EDO45311 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RSZ7])

HSP 1 Score: 260.381 bits (664), Expect = 5.030e-76
Identity = 167/546 (30.59%), Postives = 273/546 (50.00%), Query Frame = 3

Query:  711 PLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVL-ISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLW--FYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEG 2339
            PL++AA   NY ++ +L+ +G  + KPH++ C C EC    + D+ R S+ R++ YR LA+P  I ++S DP LTAFELS EL  +   E+E++ DY  L++QC +F   LL + R S E   ILN+           P    S E     +L  +  AI Y QK FV HP CQ L+    +  + G R   F+++ A +      FP +++ Y   P  ++G  +K+PF+KF+ H  S+++FL+ L + +     I F             PS  EW I  ++ G  W E KQ++  G R Y +  WN +D     L   AF L    +    DS  ++       A++ +L  ++ ++A   + S  +L+++  I+  LG LQ+SL RM+R I  F  +  +VL +++  +  L    F ++Q     K V  T  I           + +G  + N+   + +L W +  ++ L  LN+       +F    +   Y   S+++LLNM IAMM+ SYQ + +  + E+KFAR+QLW  +  + 
Sbjct:    1 PLVVAAQLGNYEVLNMLVSKGFQLVKPHNVLCRCEEC----QADNFRESQRRLDIYRGLANPVFISMTSNDPFLTAFELSSELEVIARREDEYEKDYLQLSQQCSQFTIGLLDECRTSREQRCILNY-----------PGENGSVEDYAENSLGLVNSAISYNQKEFVAHPFCQHLVMQHIFGDITGWRTNHFLYRIAYVLTQVIIFPVLAVIYFFMPFLEVGRKIKRPFVKFINHTSSFVVFLILLAVSSHHQFEIRFRKM----------PSGLEWLIFSWILGVAWSECKQVWHEGARRYFSSGWNWMDIGMVFLLLGAFVLWTIIFIVDFDSNAKL-------AHDVLLSTADGMYAFGVVASFFRLIYLCQISRYLGLLQLSLSRMVRVIFQFAFISCVVLWSFSVAMTMLYMSSFEAYQLPRPVKNV--TSDIDA--------ILDKG--YDNLLSTMVTLMWASLDMVGLDTLNVFKKQSLIQFWTAALFTLYHAASMVVLLNMLIAMMSNSYQQVEDNIETEYKFARTQLWTDYIGDA 502

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Match: EDO48346 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJX1])

HSP 1 Score: 232.261 bits (591), Expect = 1.686e-65
Identity = 187/621 (30.11%), Postives = 314/621 (50.56%), Query Frame = 3

Query:  561 EIADSLLHAISEENIEAVEILLT------AMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASP---SLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEE-TMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQ-YCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLE--YDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKS 2384
            ++  +LL A+S++N+  V+ LL         + R      L    N SN +   +TPLILA+H ++Y I+K+LL +G TI + HD  C C  C   Q    +  S  R+  YRALASP   SL  LS KDP+  AFEL+ EL  L  +E EF++DY  L++QC++FA  LL Q R  SE+  +          MS+    M+ A ++  + +L  L  AI  K   FV HP+CQ +L+S+ Y       ++    +     L     P  ++ Y  +P S L   L  P +KF+ H G++ LFLL L + +++  FI    ++ +        + S+  I I++ G I QE+K ++  G   YL+  WNL+  +   L+  + G+   A   +  S +  +     E+Y  +L++   F    +L+ +       +N  LGPLQ+SL +M++DIL F  ++ L+ +A+   + ++   YS Q   A K        T   +  Y  +C  +G         ++ ++W  F   +L   N +  +  + T+  G+++   +   SI++ +NM IAMM+ S+Q +A+  D  WKF+R+++W+ +  +G   P PF+++PS  S
Sbjct:   13 DVGAALLQAVSKDNVLYVKALLAYENNNDRFSRRSSSCVNLSKNTNDSNRY---MTPLILASHNNSYDIVKLLLSKGHTIDRVHDRGCLCPWC---QSLGRIGTSLHRLYTYRALASPVYMSLTFLSCKDPVRQAFELNKELVELADIEYEFRSDYLQLSQQCEEFAVALLDQCRDMSEIEQM----------MSVPD--MDGALTKNGSKSLGVLDYAINNKNGRFVAHPYCQMMLNSVIYGDFHTWEKMGVTLKILFALLFTIFIPVWAIVYFFTPTSCLSQKLATPILKFIMHTGAFGLFLLLLILSSIQ-RFISSNTFLLKF-----LFNFSDILITIWIFGLIVQELKDMWRQGKERYLSQWWNLVTLAMLGLFIIS-GILWVAGSALSVSKEGSLA----ESYRFILLANAFFTIGVLLAFLHFSNAVQVNSTLGPLQLSLVKMVKDILKFLLLFFLIYLAFVVALRRV---YS-QYVWAGK--------TPHTISLYSVFCSVQGS--------MRLVFWAIFDKTELEEFNTDPSFPTKITQSTGEVLFALFNIASILVAINMLIAMMSNSFQKVADSEDFLWKFSRTRMWMEYIIKGSVLPAPFSVLPSIAS 584

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Match: EDO49302 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH68])

HSP 1 Score: 166.007 bits (419), Expect = 3.591e-43
Identity = 133/528 (25.19%), Postives = 245/528 (46.40%), Query Frame = 3

Query:  369 SDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRS------RINAYRALASPSLICL------SSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFI--HQSAVIGLI-----CASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDIL 1895
            S DE+     V   D   V+S  D +  ++      D + R  L   I+    ++L++ L     I  +L +A+ + + + V+ +L  +++  K+ D+    G       + ++PL+LA H + + II++ L +G  + +PHD      +  +  + +      S      R+NAYRALASP  I         +  PI    EL+ +L      + EF  DY+ +++ CQ+FA DLL Q R + E   +L+  + ++  +     +           LS L LAI+      V HP  Q  L  + Y GL   +R P +  ++S   G +         P +++FYI++P  ++ ++LK P +KF  H G+++LF + L + + +  F          +D    P + +W  ++++ G   QE+K LY  G   Y+   WN++      L+  ++ LR+TAY + + S   + +     + +  L++   FA A + S + L     ++   GPLQ+SL  +  D++
Sbjct:   18 SADEQLLFDLVLNEDVEGVRSFFDLRPDFLFR--TRDFVTRALLSDTIDLNRGDILKIFLDEQARIGGALFNAVRKGSKDCVQTMLPYISS--KRGDI----GPEDVKPGAFVSPLMLAVHLEKFDIIELFLSKGYRVLEPHDDDDEDDDDEQLNRTNVGLELSSELSFNLRVNAYRALASPLYISYFFIMNPDALHPIFHVLELNKKLKNQMYRDFEFNNDYKQISKDCQRFAVDLLEQCRTTDETNVLLD-VYPEIQRVYEKDKKHIEGSHTAFKELSMLNLAIRNDMNELVAHPQSQLRLDKILYHGLYMFKREPRVWRYRSWYTGKLFWLRHTLLLPFLALFYIIAPDCRISNVLKTPMVKFYSHTGAFVLFAIALAVSSFEDHF----------TDYTLIPVLIDWGTLLFVLGLFLQEVKDLYFQGAFRYIRQWWNIISLLMVVLFLISYSLRLTAYLSPQTSPPHL-KNLAVRSSQLSLLANSFFAFAMVFSFIHLTNFLQVSDVFGPLQLSLYMLFADLI 525

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Match: EDO31100 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SYW3])

HSP 1 Score: 88.5817 bits (218), Expect = 1.091e-17
Identity = 68/284 (23.94%), Postives = 131/284 (46.13%), Query Frame = 3

Query: 1527 PSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSP 2378
            P+  E+ I+++  G I  E++Q   +  + Y  DMWN LD +    Y     +RI            M +    +    +     ++    +  ++++  +  +N   GPLQ++L RML D+      +V+V++A++F I ++   Y  QR  A        + +G       +C   G   + + +  +SL W+ FGL DL ++    +++    +   +   +  I ++MLLN  +A++N +Y+ I   SD EWK+ R+ ++   +      P P N+I  P
Sbjct:  484 PTAVEYVILVFFLGRILAEVQQYQRSRSKIYFRDMWNYLDITIILCYITIVIVRIVT----------MAKSGPVQGNNLLAGVMYMYGINTLFLILRVSSVLELNRTTGPLQLALMRMLVDLWVIIVQFVVVILAFSFAITKV---YFAQRSLAMGQTETNATYSG-------FCPLDGG--NCLRKTTESLVWSLFGLTDLDSIAT--NNRAASTLAYYLYAIFLVICVVMLLNTLVALLNNTYEDIKSNSDTEWKYVRA-MYADQYNRCHPFPPPVNLITVP 742

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Match: EDO38427 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SD04])

HSP 1 Score: 79.7221 bits (195), Expect = 5.575e-15
Identity = 72/332 (21.69%), Postives = 144/332 (43.37%), Query Frame = 3

Query: 1530 SISEWAIIIYLAGYIWQEIKQLYS----------------------------NGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFN-MKDSTDRMIERKYWEAYEPVLISECLFA-AANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSE 2435
            ++ EW I+++  G +  E  QL S                            + LR YL+D WN+LD  T   Y     LR+  + +  K S +R++            ++  L+   A +L++     M       G +QI+L +++  ++  F  ++   VA++  I ++              V  +Y+ T      + +C   G   +  +  ++ L W+  GL D ++L  +    F+E + K++ G +  + ++ML+NM IA+++ +YQ + + S  EW + ++ + I  +      PVPFNI+        F+L++ +    C +
Sbjct:  595 TVVEWLILVFFVGRLLNEAHQLISTKPGENNETSPNEDDSPKPDSRKKNERVDTLRKYLSDRWNILDLLTLLSYVIILILRVITWASRAKVSQNRLLA-----------VAGYLYGLNAMLLTLRVFGHMMESKKSTGAIQIALFQIIGAVVAIFGQFLAATVAFSLAITKIYM------------VEVSYA-TPSSNASHGFCSKPG--LNCWWGAVRHLSWSLLGLADTSSL--DSSDGFSEGLAKVLYGLFLIMGVVMLMNMMIALLSNTYQQVEDNSFYEWSYKKA-ITIRTYSGYHPVPVPFNIV------SLFVLLVGYLWKSCRQ 891

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Match: trpc5a (short transient receptor potential channel 5 [Source:NCBI gene;Acc:101169488])

HSP 1 Score: 661.759 bits (1706), Expect = 0.000e+0
Identity = 362/799 (45.31%), Postives = 511/799 (63.95%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEA---CKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFC------CSESHNRSKWKSIRKLVKKVNE---KEARHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPA--YTTLRNVTK 2702
             E ELS +ER YL +VE+GD   VK  L     Y  +++NC D LGR+ L IAIENE+ E++ELLL + +   D+LL+AI +E + AVE+LL+      +K+    ++ +  + FT DITP++LAAH +NY IIK+L+ R  TIP+PH +RC C ECV S + DSLRHSRSR+N Y+ALASPSLI LSS+DPILTAF L WEL  L  +ENEF+ +YE L++QC++FA DLL Q R S EL TILNH             + E  +  +   L++LKLAIKY QK FV  P+CQQLL++LWY+G PG RR  +  +     +I   FP  SM Y+L+PKS LG  +K+PFIKF+CH  SY+ FL  L + +  +           L  +GPPP++ EW I+ ++ G+IW EIK+++  G   Y+ D WNL+DF+ N+LY A   L+I AY     S      R+ WE + P LI+E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y  +  E    CKG+                C  +   FS +FE +QSL+W+ FGL++L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+F+EGGT P PFNIIPSPKS  Y ++ L H   C        ESH   K +++R+  ++  +   +   +Q V+++L+KRY+    + A  ++G+TE++  E+K DISSFR+E++++  + N + P   Y++    TK
Sbjct:   28 AEVELSAEERAYLTAVEKGDYAGVKHALREAEVYYNMDVNCLDPLGRSGLLIAIENENLEIMELLLDHGIHTGDALLYAIRKEVVGAVELLLSHRRPSGEKQVPSLMMDSQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKRFAKDLLDQARSSRELETILNHRDSD---------QSEELDPRQCHDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRHHWAVKLVTCFIIGLLFPVFSMIYLLAPKSALGRFIKKPFIKFICHTASYLTFLFLLLLASQHIART-------NLHMQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNSSR----PREEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETKASEEPNNCKGI---------------RCERQNNAFSTLFETLQSLFWSIFGLLNLYVTNVKARHEFTEFVGATMFGTYNIISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSVWYLLMWL-HNRLCRRGQPPGEESH---KCENLREFTERHADSLIQNQHYQEVIRNLVKRYVAAMIRSAKTDEGLTEENFKELKQDISSFRYEVLDL--LGNRRPPRRNYSSSSETTK 785

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Match: trpc4b (short transient receptor potential channel 4 [Source:NCBI gene;Acc:101154885])

HSP 1 Score: 660.988 bits (1704), Expect = 0.000e+0
Identity = 370/776 (47.68%), Postives = 501/776 (64.56%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKS-CKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEK-------EARHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFK 2651
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC DSLGRTAL IAIENE+ E++ELLLSYN+ + D+LLHAI +E + AVE+LL     R +K+    LL    + FT DITP+ILAAH +NY +IK+LL RG +IP+PH +RC+C EC+ S   D LR+SRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+  C++FA DLL QTR S EL  ILN+         I+P+  ES     T  L+RLKLAIKY QK FV  P+CQQLL+S WY+  PG RR  +  +      I   FP +S+FY++ PKS+ G ++++PF+KF+CH  SY+ FLL L + +  ++    G        +GPPP+  EW I+ ++ G+IW EIKQ++ NGL  Y  D WN++DF  N+LY A   L+I AY  MK           WE + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++Q L+FY    +++C G+                C+ +   FS +FE +QSL+W+ FGL+ L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ IA+ +D EWKFAR++LW+S+FEEGGT P PFNIIPSPKS C  F  I K   FC      R   K IR+  + +  +          +Q V+K+L+KRY+    + A   +G+TE++  E+K DISSFR+E++ + K
Sbjct:   25 AEAELSPMEKAYLGAVEKGDYGSVKQALEEAEIYFRININCIDSLGRTALLIAIENENLEIIELLLSYNVHVGDALLHAIRKEVVGAVELLLNHKKPRGEKQVPGILLDKQFSDFTPDITPIILAAHTNNYEVIKLLLQRGVSIPQPHAVRCSCVECMSSTDVDCLRYSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELKELSRVENEFKSEYEELSHTCKQFAKDLLDQTRSSKELEIILNYRD------DINPILDES-----TNDLARLKLAIKYCQKEFVAQPNCQQLLASRWYDKFPGWRRRHWAGKLITCFFIGLLFPLLSIFYLIFPKSRYGLLIRKPFVKFICHTASYLTFLLLLFLASQHIDST--GPNSLSHDVQGPPPTTVEWMILPWIIGFIWTEIKQMWDNGLEDYADDWWNIMDFIMNSLYLATIALKIVAYVKMKVLYVGCRPLDDWEVWHPTLLAESLFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ-LYFYYATEEKSCYGI---------------RCLQQNNAFSTLFETVQSLFWSVFGLVSLYVTNVKPPHEFTEFVGTTMFGTYNIISLVVLLNMLIAMMNNSYQHIADHADMEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSVCYLFGWIRKR--FC------RKPAKRIRQTFETLGVRYFQSYLLNHEYQEVLKNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVLGMMK 763

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Match: trpc4b (short transient receptor potential channel 4 [Source:NCBI gene;Acc:101154885])

HSP 1 Score: 660.218 bits (1702), Expect = 0.000e+0
Identity = 370/777 (47.62%), Postives = 502/777 (64.61%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKS-CKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQI--------VMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFK 2651
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC DSLGRTAL IAIENE+ E++ELLLSYN+ + D+LLHAI +E + AVE+LL     R +K+    LL    + FT DITP+ILAAH +NY +IK+LL RG +IP+PH +RC+C EC+ S   D LR+SRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+  C++FA DLL QTR S EL  ILN+         I+P+  ES     T  L+RLKLAIKY QK FV  P+CQQLL+S WY+  PG RR  +  +      I   FP +S+FY++ PKS+ G ++++PF+KF+CH  SY+ FLL L + +  ++    G        +GPPP+  EW I+ ++ G+IW EIKQ++ NGL  Y  D WN++DF  N+LY A   L+I AY  MK   D       WE + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++Q L+FY    +++C G+                C+ +   FS +FE +QSL+W+ FGL+ L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ IA+ +D EWKFAR++LW+S+FEEGGT P PFNIIPSPKS C  F  I K   FC      R   K IR+  + +  +  +  +        V+K+L+KRY+    + A   +G+TE++  E+K DISSFR+E++ + K
Sbjct:   25 AEAELSPMEKAYLGAVEKGDYGSVKQALEEAEIYFRININCIDSLGRTALLIAIENENLEIIELLLSYNVHVGDALLHAIRKEVVGAVELLLNHKKPRGEKQVPGILLDKQFSDFTPDITPIILAAHTNNYEVIKLLLQRGVSIPQPHAVRCSCVECMSSTDVDCLRYSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELKELSRVENEFKSEYEELSHTCKQFAKDLLDQTRSSKELEIILNYRD------DINPILDES-----TNDLARLKLAIKYCQKEFVAQPNCQQLLASRWYDKFPGWRRRHWAGKLITCFFIGLLFPLLSIFYLIFPKSRYGLLIRKPFVKFICHTASYLTFLLLLFLASQHIDST--GPNSLSHDVQGPPPTTVEWMILPWIIGFIWTEIKQMWDNGLEDYADDWWNIMDFIMNSLYLATIALKIVAYVKMKVLDD-------WEVWHPTLLAESLFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ-LYFYYATEEKSCYGI---------------RCLQQNNAFSTLFETVQSLFWSVFGLVSLYVTNVKPPHEFTEFVGTTMFGTYNIISLVVLLNMLIAMMNNSYQHIADHADMEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSVCYLFGWIRKR--FC------RKPAKRIRQTFETLGVRYFQSYLLNIYFFSEVLKNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVLGMMK 757

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Match: trpc4b (short transient receptor potential channel 4 [Source:NCBI gene;Acc:101154885])

HSP 1 Score: 657.907 bits (1696), Expect = 0.000e+0
Identity = 369/777 (47.49%), Postives = 502/777 (64.61%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKS-CKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQI--------VMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFK 2651
             E ELS  E+ YL +VE+GD   VK  L+    Y  +NINC DSLGRTAL IAIENE+ E++ELLLSYN+ + D+LLHAI +E + AVE+LL     R +K+    LL    + FT DITP+ILAAH +NY +IK+LL RG +IP+PH +RC+C EC+ S   D LR+SRSR+N Y+ALASPSLI LSS+DP LTAF+LSWEL  L  +ENEFK++YE L+  C++FA DLL QTR S EL  ILN+         I+P+  ES     T  L+RLKLAIKY QK FV  P+CQQLL+S WY+  PG RR  +  +      I   FP +S+FY++ PKS+ G ++++PF+KF+CH  SY+ FLL L + +  ++    G        +GPPP+  EW I+ ++ G+IW EIKQ++ NGL  Y  D WN++DF  N+LY A   L+I AY  MK+          WE + P L++E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++Q L+FY    +++C G+                C+ +   FS +FE +QSL+W+ FGL+ L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ IA+ +D EWKFAR++LW+S+FEEGGT P PFNIIPSPKS C  F  I K   FC      R   K IR+  + +  +  +  +        V+K+L+KRY+    + A   +G+TE++  E+K DISSFR+E++ + K
Sbjct:   25 AEAELSPMEKAYLGAVEKGDYGSVKQALEEAEIYFRININCIDSLGRTALLIAIENENLEIIELLLSYNVHVGDALLHAIRKEVVGAVELLLNHKKPRGEKQVPGILLDKQFSDFTPDITPIILAAHTNNYEVIKLLLQRGVSIPQPHAVRCSCVECMSSTDVDCLRYSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELKELSRVENEFKSEYEELSHTCKQFAKDLLDQTRSSKELEIILNYRD------DINPILDES-----TNDLARLKLAIKYCQKEFVAQPNCQQLLASRWYDKFPGWRRRHWAGKLITCFFIGLLFPLLSIFYLIFPKSRYGLLIRKPFVKFICHTASYLTFLLLLFLASQHIDST--GPNSLSHDVQGPPPTTVEWMILPWIIGFIWTEIKQMWDNGLEDYADDWWNIMDFIMNSLYLATIALKIVAYVKMKNHC-----MDDWEVWHPTLLAESLFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQ-LYFYYATEEKSCYGI---------------RCLQQNNAFSTLFETVQSLFWSVFGLVSLYVTNVKPPHEFTEFVGTTMFGTYNIISLVVLLNMLIAMMNNSYQHIADHADMEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSVCYLFGWIRKR--FC------RKPAKRIRQTFETLGVRYFQSYLLNIYFFSEVLKNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVLGMMK 759

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BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Match: trpc5a (short transient receptor potential channel 5 [Source:NCBI gene;Acc:101169488])

HSP 1 Score: 657.136 bits (1694), Expect = 0.000e+0
Identity = 361/796 (45.35%), Postives = 506/796 (63.57%), Query Frame = 3

Query:  354 TEEELSDDERKYLLSVERGDAPYVKSILDNKNKYV-LNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEA---CKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFC------CSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQR-QKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPA--YTTLRNVTK 2702
             E ELS +ER YL +VE+GD   VK  L     Y  +++NC D LGR+ L IAIENE+ E++ELLL + +   D+LL+AI +E + AVE+LL+      +K+    ++ +  + FT DITP++LAAH +NY IIK+L+ R  TIP+PH +RC C ECV S + DSLRHSRSR+N Y+ALASPSLI LSS+DPILTAF L WEL  L  +ENEF+ +YE L++QC++FA DLL Q R S EL TILNH             + E  +  +   L++LKLAIKY QK FV  P+CQQLL++LWY+G PG RR  +  +     +I   FP  SM Y+L+PKS LG  +K+PFIKF+CH  SY+ FL  L + +  +           L  +GPPP++ EW I+ ++ G+IW EIK+++  G   Y+ D WNL+DF+ N+LY A   L+I AY     S      R+ WE + P LI+E LFA ANI S ++L+ +FT N  LGPLQISLGRML DIL F  +Y LVL+A+A G++QL ++Y  +  E    CKG+                C  +   FS +FE +QSL+W+ FGL++L   N++  H+FTEF+G  M G+Y  IS+++LLNM IAMMN SYQ+IA+ +D EWKFAR++LW+S+F+EGGT P PFNIIPSPKS  Y ++ L H   C        ESH   K +++R+  +           V+++L+KRY+    + A  ++G+TE++  E+K DISSFR+E++++  + N + P   Y++    TK
Sbjct:   25 AEVELSAEERAYLTAVEKGDYAGVKHALREAEVYYNMDVNCLDPLGRSGLLIAIENENLEIMELLLDHGIHTGDALLYAIRKEVVGAVELLLSHRRPSGEKQVPSLMMDSQFSEFTPDITPIMLAAHTNNYEIIKLLVQRKVTIPRPHQIRCDCVECVSSSEVDSLRHSRSRLNIYKALASPSLIALSSEDPILTAFRLGWELKELSKVENEFRQEYEELSQQCKRFAKDLLDQARSSRELETILNHRDSD---------QSEELDPRQCHDLAKLKLAIKYHQKEFVAQPNCQQLLATLWYDGFPGWRRHHWAVKLVTCFIIGLLFPVFSMIYLLAPKSALGRFIKKPFIKFICHTASYLTFLFLLLLASQHIART-------NLHMQGPPPTVVEWMILPWVLGFIWAEIKEMWDGGFTEYIHDWWNLMDFAMNSLYLATISLKIVAYVKYNSSR----PREEWEMWHPTLIAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYETKASEEPNNCKGI---------------RCERQNNAFSTLFETLQSLFWSIFGLLNLYVTNVKARHEFTEFVGATMFGTYNIISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFDEGGTLPPPFNIIPSPKSVWYLLMWL-HNRLCRRGQPPGEESH---KCENLREFTE-----------VIRNLVKRYVAAMIRSAKTDEGLTEENFKELKQDISSFRYEVLDL--LGNRRPPRRNYSSSSETTK 768

[Close]

BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Match: SMESG000078533.1 (SMESG000078533.1)

HSP 1 Score: 1983.38 bits (5137), Expect = 0.000e+0
Identity = 988/991 (99.70%), Postives = 989/991 (99.80%), Query Frame = 3

Query:  246 QPPPGEIELRKKLSKMIDDLNFDIQTGLEKSGISSNTEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIMRKTNLPGXXXXXXXXXXXXXXXXXLDNMIDKVSKFPNRSEIESTAKKKFPVAFDNEGFQSSESDLQLPTPLTQIIITEEDDTNMRKMSTNFNDASQQPLNVSRFLQDSNIYKRKPSFPSSGSKNDMKHAASADNVQNQTSQSPIGTKPLSEHRRVDMV 3218
            QPPPGEIELRKKLSKMIDDLNFDIQTGLEKSGISSNTEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIENEHNEMLELLLSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAII+YL GYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIMRKTNLPGNSNNVNNNIINNNNNNNLDNMIDKVSKFPNRSEIESTAKKKFPVAFDNEGFQSSESDLQLPTPLTQIIITEEDDTNMRKMSTNFNDASQQPLNVSRFLQDSNIYKRKPSFPSSGSKNDMKHAASADNVQN TSQSPIGTKPLSEHRRVDMV
Sbjct:   18 QPPPGEIELRKKLSKMIDDLNFDIQTGLEKSGISSNTEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIENEHNEMLELLLSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIVYLTGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIMRKTNLPGNSNNVNNNIINNNNNNNLDNMIDKVSKFPNRSEIESTAKKKFPVAFDNEGFQSSESDLQLPTPLTQIIITEEDDTNMRKMSTNFNDASQQPLNVSRFLQDSNIYKRKPSFPSSGSKNDMKHAASADNVQNPTSQSPIGTKPLSEHRRVDMV 1008

[Close]

BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Match: SMESG000039904.1 (SMESG000039904.1)

HSP 1 Score: 928.702 bits (2399), Expect = 0.000e+0
Identity = 465/795 (58.49%), Postives = 598/795 (75.22%), Query Frame = 3

Query:  378 ERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEAC---KGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILK-HCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIMRK 2750
            ER++LL+VER D   +K  LD+  K   NINC D LGR A+ IAIE EH E+LELLL Y+L++ D+LLHAI+EEN EAVEI++ A      +K   D   N S++FT DITP+ILA+HRDNY IIK+LLDRGD IPKPHDLRCAC  CV+SQK+DSLRHS+SRINAY+ALASPSLI LSSKDPILTAFELSWEL RLG LENEFK +YE+L+ +C+ FA  LL QTRGS ELA +LNH +G  +  +++    +S    +T  L+RLKLAIKY QKSFV HPHCQQLL+SLWYEGLPG RR PF+++  +I  I A FP ++  Y++ P+S    ++K+PFIKF+CH  SYMLFLL L + A+++E+    N++E    RG  P++ EW +IIY+AG+IWQE+K+L+ NG++ Y+ DMWNLLDF+TN+LY A   LR  AY+   +     + R  W++Y+P LISECLFAAANI S +KLV++FT+NP LGPLQISLGRML DI+ FF +Y+LVLVA+A G++QLLWFY+ +R E C   K   F  +    + E Y YC TRG+YF+++FEI+QSLYW+ +GL+DL+NLNLEY HQFTEF+GKLM G+Y +I++I+LLNM IAMMNTSYQ+IAE++D EWKFARS+LWIS+FE+G T PVPFNII SPK+  Y     K +CL  C     +S+W SI+K+V KVNE E R+Q VM +LI RYL+ RQKA +N+GVTEDDLNEIKGDIS+FRFEL++I K N M     +     +KLR KGSKK  +R+ ++
Sbjct:   58 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNAILIAIEYEHIELLELLLKYDLDLGDALLHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQALASPSLIALSSKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSL--IDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMLFLLLLILAALRIEY----NHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIISMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCL--CKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNVSSDRGLRSKLRRKGSKKSMSRLNQR 844

[Close]

BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Match: SMESG000039904.1 (SMESG000039904.1)

HSP 1 Score: 927.546 bits (2396), Expect = 0.000e+0
Identity = 465/795 (58.49%), Postives = 598/795 (75.22%), Query Frame = 3

Query:  378 ERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEAC---KGVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILK-HCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIMRK 2750
            ER++LL+VER D   +K  LD+  K   NINC D LGR A+ IAIE EH E+LELLL Y+L++ D+LLHAI+EEN EAVEI++ A      +K   D   N S++FT DITP+ILA+HRDNY IIK+LLDRGD IPKPHDLRCAC  CV+SQK+DSLRHS+SRINAY+ALASPSLI LSSKDPILTAFELSWEL RLG LENEFK +YE+L+ +C+ FA  LL QTRGS ELA +LNH +G  +  +++    +S    +T  L+RLKLAIKY QKSFV HPHCQQLL+SLWYEGLPG RR PF+++  +I  I A FP ++  Y++ P+S    ++K+PFIKF+CH  SYMLFLL L + A+++E+    N++E    RG  P++ EW +IIY+AG+IWQE+K+L+ NG++ Y+ DMWNLLDF+TN+LY A   LR  AY+   +     + R  W++Y+P LISECLFAAANI S +KLV++FT+NP LGPLQISLGRML DI+ FF +Y+LVLVA+A G++QLLWFY+ +R E C   K   F  +    + E Y YC TRG+YF+++FEI+QSLYW+ +GL+DL+NLNLEY HQFTEF+GKLM G+Y +I++I+LLNM IAMMNTSYQ+IAE++D EWKFARS+LWIS+FE+G T PVPFNII SPK+  Y     K +CL  C     +S+W SI+K+V KVNE E R+Q VM +LI RYL+ RQKA +N+GVTEDDLNEIKGDIS+FRFEL++I K N M     +     +KLR KGSKK  +R+ ++
Sbjct:   55 ERQFLLAVERSDIASIKRFLDSSQKTGFNINCRDPLGRNAILIAIEYEHIELLELLLKYDLDLGDALLHAINEENFEAVEIIINAQIEVHDQKPSTDYTSNLSSSFTPDITPIILASHRDNYEIIKLLLDRGDRIPKPHDLRCACDICVESQKQDSLRHSKSRINAYQALASPSLIALSSKDPILTAFELSWELKRLGRLENEFKAEYEILSTKCEDFARALLEQTRGSEELAILLNHSNGSFSNRTLNERNADSL--IDTHGLARLKLAIKYNQKSFVAHPHCQQLLASLWYEGLPGFRRRPFLYKVGMIFGISAMFPMLATIYLIYPRSTFAGLMKKPFIKFICHSSSYMLFLLLLILAALRIEY----NHLENDDYRGNTPTVIEWILIIYIAGFIWQEVKELWENGVKGYIMDMWNLLDFATNSLYVATISLRAVAYYKSSNENIISMGRPKWDSYDPTLISECLFAAANIFSTLKLVYIFTVNPNLGPLQISLGRMLNDIMKFFLIYMLVLVAFACGLNQLLWFYAKKRVETCSDDKNKYFLPTNNYSQNELYNYCATRGKYFTSLFEIVQSLYWSTYGLVDLSNLNLEYPHQFTEFVGKLMFGTYSFITLIVLLNMLIAMMNTSYQLIAEQADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKTIYYLFFWFKMNCL--CKSKGKKSRWHSIKKIVSKVNEMEQRYQKVMNNLIMRYLLHRQKAEDNEGVTEDDLNEIKGDISAFRFELLDILKNNGMTVNVSSDRGLRSKLRRKGSKKSMSRLNQR 841

[Close]

BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Match: SMESG000077497.1 (SMESG000077497.1)

HSP 1 Score: 867.07 bits (2239), Expect = 0.000e+0
Identity = 431/769 (56.05%), Postives = 578/769 (75.16%), Query Frame = 3

Query:  378 ERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIE-RKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGV---VFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTP 2672
            ER +L++VER D   VKS LDN      NINC DSLGR A+ IAI+NEH ++L+LLL Y ++++D+LL AI EE++E+VE+++ A +T+ + K++ +   +  ++FT DITP+ILAAH+DNY IIK+LLDRGD IPKPHDLRC+C  CV++QK DSL HS SRINAY+ALASP LI LSSKDP+LTAFELSWEL+RL  LENEF ++YE L+++C++FAT LL QTR SSELA +LNH     N+ S+    +   +S +T +L+RLKLAIKY QKSFV +PHCQQLL+S WYEGLPG RR PFI++  +I  +   FP + + Y++ P+SK+G ++++PFIKF+CH  SY++FL  L + A+++EF       E +  R  PP+  E  +++Y+ G+IWQEIK+L+  G++ Y+ DMWNLLDF+TNALY A   LR  AY+   +  + + E R  W++Y+P+LISECLF+AANI S +KLV +FT+NP LGPLQISLGRML DIL FF +Y+LVL+A+A G++QLLWFY+ +R++ C       F  S      + Y YC TRG+YF+N+FEI+QSLYW+ +GL+DLT LNLEY H+FTEF+GKLM G Y  I++++LLNM IAMMNTSYQII EK+D EWKFARS+LWIS+FE+G T PVPFNII SPK+  YF+  +    FC S+   +SKW+SI+K+V KVNE E R+Q VM++L+ RYL+ RQK  + Q VTEDD+NEIKGDIS+FR+EL++I K N M  P
Sbjct:   24 ERLFLMAVERSDISTVKSYLDNAAVLNFNINCRDSLGRNAVLIAIDNEHTDLLQLLLQYEMDLSDALLRAIDEEHLESVELIIAAQSTKTEDKNIDESRSSLISSFTPDITPIILAAHKDNYEIIKVLLDRGDRIPKPHDLRCSCQICVEAQKIDSLHHSMSRINAYKALASPCLIALSSKDPVLTAFELSWELSRLSRLENEFASEYEKLSKKCEEFATALLEQTRESSELAVLLNH-----NSTSVGVNDINYGDSFQTHSLTRLKLAIKYNQKSFVANPHCQQLLASFWYEGLPGFRRKPFIYKLTIISALGFMFPGLGVVYLVFPRSKIGRLMRKPFIKFICHSASYIIFLALLILAALRIEF----TNSEVMESRQNPPTAIECLLVVYICGFIWQEIKELWIAGVKCYIMDMWNLLDFATNALYVATISLRAVAYYKFNNVENLLQEQRPKWDSYDPILISECLFSAANIFSTLKLVSIFTMNPHLGPLQISLGRMLNDILKFFCVYMLVLIAFACGLNQLLWFYAKKRRDICAKSSHRFFQPSEKEPVSDLYNYCATRGKYFTNLFEIVQSLYWSTYGLVDLTYLNLEYPHEFTEFVGKLMFGVYSVITLVVLLNMLIAMMNTSYQIIVEKADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKAIYYFLRWIHLNWFCKSKGR-KSKWQSIKKIVTKVNEMEQRYQKVMENLVMRYLMLRQKKEDKQEVTEDDINEIKGDISAFRYELLDILKSNGMDIP 782

[Close]

BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Match: SMESG000077497.1 (SMESG000077497.1)

HSP 1 Score: 865.914 bits (2236), Expect = 0.000e+0
Identity = 431/769 (56.05%), Postives = 578/769 (75.16%), Query Frame = 3

Query:  378 ERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRTALHIAIXXXXXXXXXXXXSYNLEIADSLLHAISEENIEAVEILLTAMATRPKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPHDLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFELSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHDHGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLSSLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQPFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEWAIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRITAYFNMKDSTDRMIE-RKYWEAYEPVLISECLFAAANILSVMKLVFMFTINPRLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACKGV---VFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLNLEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEWKFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHNRSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDLNEIKGDISSFRFELIEIFKMNNMKTP 2672
            ER +L++VER D   VKS LDN      NINC DSLGR A+ IAI+NEH ++L+LLL Y ++++D+LL AI EE++E+VE+++ A +T+ + K++ +   +  ++FT DITP+ILAAH+DNY IIK+LLDRGD IPKPHDLRC+C  CV++QK DSL HS SRINAY+ALASP LI LSSKDP+LTAFELSWEL+RL  LENEF ++YE L+++C++FAT LL QTR SSELA +LNH     N+ S+    +   +S +T +L+RLKLAIKY QKSFV +PHCQQLL+S WYEGLPG RR PFI++  +I  +   FP + + Y++ P+SK+G ++++PFIKF+CH  SY++FL  L + A+++EF       E +  R  PP+  E  +++Y+ G+IWQEIK+L+  G++ Y+ DMWNLLDF+TNALY A   LR  AY+   +  + + E R  W++Y+P+LISECLF+AANI S +KLV +FT+NP LGPLQISLGRML DIL FF +Y+LVL+A+A G++QLLWFY+ +R++ C       F  S      + Y YC TRG+YF+N+FEI+QSLYW+ +GL+DLT LNLEY H+FTEF+GKLM G Y  I++++LLNM IAMMNTSYQII EK+D EWKFARS+LWIS+FE+G T PVPFNII SPK+  YF+  +    FC S+   +SKW+SI+K+V KVNE E R+Q VM++L+ RYL+ RQK  + Q VTEDD+NEIKGDIS+FR+EL++I K N M  P
Sbjct:   11 ERLFLMAVERSDISTVKSYLDNAAVLNFNINCRDSLGRNAVLIAIDNEHTDLLQLLLQYEMDLSDALLRAIDEEHLESVELIIAAQSTKTEDKNIDESRSSLISSFTPDITPIILAAHKDNYEIIKVLLDRGDRIPKPHDLRCSCQICVEAQKIDSLHHSMSRINAYKALASPCLIALSSKDPVLTAFELSWELSRLSRLENEFASEYEKLSKKCEEFATALLEQTRESSELAVLLNH-----NSTSVGVNDINYGDSFQTHSLTRLKLAIKYNQKSFVANPHCQQLLASFWYEGLPGFRRKPFIYKLTIISALGFMFPGLGVVYLVFPRSKIGRLMRKPFIKFICHSASYIIFLALLILAALRIEF----TNSEVMESRQNPPTAIECLLVVYICGFIWQEIKELWIAGVKCYIMDMWNLLDFATNALYVATISLRAVAYYKFNNVENLLQEQRPKWDSYDPILISECLFSAANIFSTLKLVSIFTMNPHLGPLQISLGRMLNDILKFFCVYMLVLIAFACGLNQLLWFYAKKRRDICAKSSHRFFQPSEKEPVSDLYNYCATRGKYFTNLFEIVQSLYWSTYGLVDLTYLNLEYPHEFTEFVGKLMFGVYSVITLVVLLNMLIAMMNTSYQIIVEKADIEWKFARSKLWISYFEDGNTLPVPFNIIISPKAIYYFLRWIHLNWFCKSKGR-KSKWQSIKKIVTKVNEMEQRYQKVMENLVMRYLMLRQKKEDKQEVTEDDINEIKGDISAFRYELLDILKSNGMDIP 769

The following BLAST results are available for this feature:

BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
BLAST of Short transient receptor potential channel 4 vs. TrEMBL
BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
BLAST of Short transient receptor potential channel 4 vs. Ensembl Yeast
BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST

BLAST of Short transient receptor potential channel 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TRPC4	0.000e+0	46.92	transient receptor potential cation channel subfam...	[more]
TRPC4	0.000e+0	46.92	transient receptor potential cation channel subfam...	[more]
TRPC4	0.000e+0	46.55	transient receptor potential cation channel subfam...	[more]
TRPC5	0.000e+0	44.83	transient receptor potential cation channel subfam...	[more]
TRPC4	0.000e+0	47.62	transient receptor potential cation channel subfam...	[more]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trp-2	0.000e+0	46.50	TRP (Transient receptor potential) channel family;...	[more]
trp-2	0.000e+0	46.96	TRP (Transient receptor potential) channel family;...	[more]
trp-1	2.196e-166	36.56	Transient-receptor-potential-like protein [Source...	[more]
trp-1	1.644e-163	37.08	Transient-receptor-potential-like protein [Source...	[more]
spe-41	3.502e-25	20.99	TRP homologous cation channel protein; TRP-3 chann...	[more]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Trpgamma	0.000e+0	49.14	gene:FBgn0032593 transcript:FBtr0335144	[more]
Trpgamma	0.000e+0	48.54	gene:FBgn0032593 transcript:FBtr0080945	[more]
Trpgamma	0.000e+0	48.54	gene:FBgn0032593 transcript:FBtr0080946	[more]
trpl	0.000e+0	43.72	gene:FBgn0005614 transcript:FBtr0088471	[more]
trpl	0.000e+0	43.72	gene:FBgn0005614 transcript:FBtr0301662	[more]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trpc4b	0.000e+0	46.34	transient receptor potential cation channel, subfa...	[more]
trpc4b	0.000e+0	46.34	transient receptor potential cation channel, subfa...	[more]
trpc5a	0.000e+0	45.14	transient receptor potential cation channel, subfa...	[more]
trpc5a	0.000e+0	45.24	transient receptor potential cation channel, subfa...	[more]
trpc5a	0.000e+0	45.24	transient receptor potential cation channel, subfa...	[more]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hint1	0.000e+0	47.23	histidine triad nucleotide binding protein 1 [Sour...	[more]
TRPC5	0.000e+0	44.93	transient receptor potential cation channel, subfa...	[more]
TRPC1	6.484e-166	38.31	transient receptor potential cation channel, subfa...	[more]
TRPC1	1.530e-165	38.50	transient receptor potential cation channel, subfa...	[more]
TRPC1	7.425e-165	38.50	transient receptor potential cation channel, subfa...	[more]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Trpc4	0.000e+0	45.71	transient receptor potential cation channel, subfa...	[more]
Trpc4	0.000e+0	46.79	transient receptor potential cation channel, subfa...	[more]
Trpc5	0.000e+0	44.96	transient receptor potential cation channel, subfa...	[more]
Trpc1	4.189e-168	39.03	transient receptor potential cation channel, subfa...	[more]
Trpc1	1.138e-157	36.75	transient receptor potential cation channel, subfa...	[more]

BLAST of Short transient receptor potential channel 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9VJJ7\|TRPG_DROME	0.000e+0	48.54	Transient receptor potential-gamma protein OS=Dros...	[more]
sp\|Q9QUQ5\|TRPC4_MOUSE	0.000e+0	45.71	Short transient receptor potential channel 4 OS=Mu...	[more]
sp\|P79100\|TRPC4_BOVIN	0.000e+0	46.79	Short transient receptor potential channel 4 OS=Bo...	[more]
sp\|Q9UBN4\|TRPC4_HUMAN	0.000e+0	46.92	Short transient receptor potential channel 4 OS=Ho...	[more]
sp\|O35119\|TRPC4_RAT	0.000e+0	46.66	Short transient receptor potential channel 4 OS=Ra...	[more]

BLAST of Short transient receptor potential channel 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267FS73	0.000e+0	60.63	ANK_REP_REGION domain-containing protein OS=Macros...	[more]
A0A267DGY4	0.000e+0	60.63	ANK_REP_REGION domain-containing protein OS=Macros...	[more]
A0A267F969	0.000e+0	60.48	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267DBT5	0.000e+0	60.08	ANK_REP_REGION domain-containing protein OS=Macros...	[more]
A0A4Z2DCP6	0.000e+0	56.55	Transient receptor potential-gamma protein OS=Schi...	[more]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trpc4b	0.000e+0	46.99	short transient receptor potential channel 4-like ...	[more]
trpc5a	0.000e+0	45.14	short transient receptor potential channel 5-like ...	[more]
trpc4a	0.000e+0	46.44	short transient receptor potential channel 4-like ...	[more]
trpc5b	0.000e+0	44.09	transient receptor potential cation channel, subfa...	[more]
trpc1	5.156e-157	36.94	transient receptor potential cation channel subfam...	[more]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trpc4b	2.735e-147	41.94	transient receptor potential cation channel, subfa...	[more]
trpc4b	9.405e-143	40.78	transient receptor potential cation channel, subfa...	[more]
trpc3	2.177e-126	33.01	transient receptor potential cation channel, subfa...	[more]
ENSPMAT00000007332.1	2.825e-16	23.15	pep scaffold:Pmarinus_7.0:GL483392:1130:9476:1 gen...	[more]
ENSPMAT00000007334.1	3.400e-16	23.15	pep scaffold:Pmarinus_7.0:GL483392:1130:8888:1 gen...	[more]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Short transient receptor potential channel 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO45311	5.030e-76	30.59	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48346	1.686e-65	30.11	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49302	3.591e-43	25.19	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO31100	1.091e-17	23.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38427	5.575e-15	21.69	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Short transient receptor potential channel 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
trpc5a	0.000e+0	45.31	short transient receptor potential channel 5 [Sour...	[more]
trpc4b	0.000e+0	47.68	short transient receptor potential channel 4 [Sour...	[more]
trpc4b	0.000e+0	47.62	short transient receptor potential channel 4 [Sour...	[more]
trpc4b	0.000e+0	47.49	short transient receptor potential channel 4 [Sour...	[more]
trpc5a	0.000e+0	45.35	short transient receptor potential channel 5 [Sour...	[more]

BLAST of Short transient receptor potential channel 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000078533.1	0.000e+0	99.70	SMESG000078533.1	[more]
SMESG000039904.1	0.000e+0	58.49	SMESG000039904.1	[more]
SMESG000039904.1	0.000e+0	58.49	SMESG000039904.1	[more]
SMESG000077497.1	0.000e+0	56.05	SMESG000077497.1	[more]
SMESG000077497.1	0.000e+0	56.05	SMESG000077497.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30026628 ID=SMED30026628|Name=Short transient receptor potential channel 4|organism=Schmidtea mediterranea sexual|type=transcript|length=3375bp
TAATATTTTGAGAGATTTTATTCGTTGTTTTCCACAAGAGAAAGAGATAT
CTCTCGATGCATTCTCAATTCTCTACATATACTCAGCACATGAGATTATT
GGCTAGGGCGGTTACCCATTTATGCAATAGCTTTCTCAATTACTAAATTT
CCAATTAACACTTCCGATTCCCAGATTGAACAATTCAAAAACAAATGAGT
GATTCCAATAACAGTAATGATAATGGTAATAATTTGAATGACTTGCAACC
ACCCCCCGGTGAAATTGAATTGAGAAAAAAATTATCAAAAATGATTGATG
ATTTGAATTTTGATATTCAAACCGGTCTGGAAAAGTCAGGAATCTCATCG
AACACAGAGGAAGAATTGTCAGATGACGAGAGGAAATATTTACTATCTGT
CGAAAGAGGTGACGCTCCGTATGTGAAATCGATACTTGACAACAAAAATA
AATATGTTTTGAATATCAACTGTGCCGATTCGTTGGGAAGAACTGCCTTG
CACATTGCCATCGAGAATGAACACAACGAAATGCTGGAGCTTTTATTGTC
ATACAATTTAGAAATCGCCGATTCTCTACTACATGCCATTTCAGAAGAAA
ATATCGAAGCAGTGGAAATTCTTCTAACAGCAATGGCCACCAGACCTAAA
AAGAAAGATTTACTTGATTTATTGGGGAATTCTTCTAACGCATTTACATC
TGATATTACTCCTTTAATTCTCGCGGCTCATAGAGACAATTATCCCATTA
TTAAAATTCTTCTCGATCGCGGTGACACAATTCCTAAACCCCATGACCTT
CGATGCGCTTGTCATGAATGCGTAAAATCTCAAAAAGAGGACAGCTTGAG
ACATTCTCGATCACGTATTAACGCATACAGAGCTCTAGCAAGTCCATCAC
TTATTTGCTTGTCTAGTAAGGATCCTATATTAACTGCATTCGAGCTTAGC
TGGGAGTTGAATAGACTGGGGATTTTAGAAAACGAATTTAAAACTGACTA
CGAAATGCTTGCAGAGCAATGCCAAAAGTTTGCAACAGACCTATTAGCCC
AAACTCGTGGATCGTCAGAGCTAGCGACAATACTCAATCATGACCATGGG
CAAGTGAATACGATGTCAATTAGTCCTTTGAGAATGGAATCAGCTGAATC
CGAAGAAACGATGACTTTATCCCGACTGAAGTTAGCGATTAAATACAAAC
AAAAAAGTTTTGTGGTACATCCTCATTGCCAACAACTGCTCTCGTCTCTT
TGGTATGAGGGTCTCCCAGGTATTCGCCGTTTACCTTTCATCCATCAGAG
TGCCGTTATTGGGTTGATATGTGCCTCTTTTCCCGCAATTTCTATGTTTT
ATATTTTATCTCCGAAGAGCAAATTAGGATCAATATTGAAACAGCCCTTC
ATTAAGTTTCTTTGCCATCAAGGCAGCTACATGCTATTTCTATTATTTCT
TACAATATGCGCAATGAAAGTGGAGTTCATTCTTTTCGGGAACTACGTAG
AGCGACTAAGTGATCGCGGTCCCCCTCCAAGCATTTCCGAGTGGGCCATT
ATTATATATCTGGCGGGATATATTTGGCAAGAAATAAAACAGCTATATTC
AAATGGACTACGAGCCTACCTAGCTGACATGTGGAATTTGTTGGATTTCT
CCACTAATGCTCTATATAGTGCCGCATTTGGATTGAGAATAACAGCTTAT
TTTAATATGAAAGACAGTACGGATCGAATGATTGAGAGAAAGTACTGGGA
AGCATACGAGCCTGTGCTTATTTCCGAATGTCTGTTTGCTGCTGCCAATA
TTTTGAGTGTTATGAAGCTAGTATTTATGTTTACAATCAACCCAAGACTT
GGACCATTACAGATTTCACTGGGAAGGATGCTCAGAGACATTTTAAATTT
TTTCTCCATGTATGTACTAGTATTGGTTGCATACGCCTTTGGAATTCATC
AATTGTTATGGTTTTATTCACACCAGAGGCAAGAGGCTTGTAAAGGTGTT
GTATTTACTTATTCAATTACTGGCCAAGAACTTGAAAGATATCAGTATTG
CATAACAAGAGGTCGTTATTTTTCAAATATTTTTGAGATAATCCAATCTC
TCTATTGGACTGCATTCGGACTGATAGATTTGACGAATCTCAATTTGGAG
TATGACCACCAATTTACTGAATTCATAGGCAAACTTATGTTGGGATCATA
CTGCTATATATCAATTATAATGCTGCTAAATATGTTTATTGCCATGATGA
ATACTTCTTATCAAATTATAGCCGAAAAATCAGACAAAGAATGGAAATTT
GCAAGATCCCAGCTGTGGATAAGTTTCTTTGAAGAAGGAGGAACTACTCC
AGTTCCATTTAACATTATCCCTTCACCAAAATCTTGCAAATACTTCATTC
TTATACTAAAACATTGTCTGTTCTGTTGCAGTGAGAGTCACAATAGGAGT
AAATGGAAAAGTATCAGGAAATTGGTCAAAAAAGTCAATGAAAAAGAAGC
CAGGCATCAAATCGTTATGAAAGACTTAATCAAGAGATATCTTATTCAAA
GACAGAAAGCAGGAGAAAATCAAGGAGTTACAGAAGATGATCTCAATGAA
ATTAAAGGAGATATTAGTTCATTTCGGTTTGAGCTCATTGAAATATTTAA
AATGAACAACATGAAAACTCCAGCATATACAACATTGAGAAATGTGACCA
AATTAAGGCACAAAGGAAGTAAAAAAGGATTTAATCGAATAATGCGCAAA
ACAAATCTGCCCGGGAATTCCAACAATGTGAATAATAATATTATTAATAA
CAATAACAATAACAATCTTGACAATATGATTGATAAAGTATCAAAATTCC
CAAATAGAAGTGAAATTGAATCGACCGCCAAAAAGAAATTTCCTGTGGCT
TTTGACAATGAAGGATTTCAAAGTTCCGAATCAGATTTGCAACTACCGAC
TCCATTAACTCAGATTATAATTACGGAAGAAGATGATACCAATATGAGAA
AAATGAGCACAAACTTTAACGATGCAAGCCAGCAACCACTGAATGTATCA
AGGTTTCTTCAAGATTCCAATATTTATAAGAGAAAGCCTAGCTTTCCCTC
TTCTGGTAGTAAAAATGACATGAAACATGCAGCGAGTGCCGATAATGTCC
AGAATCAAACTTCACAATCACCCATTGGCACTAAACCCTTATCAGAACAT
CGTCGAGTTGATATGGTTTAAATTCAACATTATGTTTGGCCTATGCCACT
TGGACTTGCCTTATGAAACCTATTGGATATTCTTTCTGCACACAGCTTTA
AAAAAGGCATGGAACCAATTCCAATGAATATTTTCACATCGTTCTATCTA
TAAACACTAAATAAAATGTCTCAGC

protein sequence of SMED30026628-orf-1

>SMED30026628-orf-1 ID=SMED30026628-orf-1|Name=SMED30026628-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1009bp
MSDSNNSNDNGNNLNDLQPPPGEIELRKKLSKMIDDLNFDIQTGLEKSGI
SSNTEEELSDDERKYLLSVERGDAPYVKSILDNKNKYVLNINCADSLGRT
ALHIAIENEHNEMLELLLSYNLEIADSLLHAISEENIEAVEILLTAMATR
PKKKDLLDLLGNSSNAFTSDITPLILAAHRDNYPIIKILLDRGDTIPKPH
DLRCACHECVKSQKEDSLRHSRSRINAYRALASPSLICLSSKDPILTAFE
LSWELNRLGILENEFKTDYEMLAEQCQKFATDLLAQTRGSSELATILNHD
HGQVNTMSISPLRMESAESEETMTLSRLKLAIKYKQKSFVVHPHCQQLLS
SLWYEGLPGIRRLPFIHQSAVIGLICASFPAISMFYILSPKSKLGSILKQ
PFIKFLCHQGSYMLFLLFLTICAMKVEFILFGNYVERLSDRGPPPSISEW
AIIIYLAGYIWQEIKQLYSNGLRAYLADMWNLLDFSTNALYSAAFGLRIT
AYFNMKDSTDRMIERKYWEAYEPVLISECLFAAANILSVMKLVFMFTINP
RLGPLQISLGRMLRDILNFFSMYVLVLVAYAFGIHQLLWFYSHQRQEACK
GVVFTYSITGQELERYQYCITRGRYFSNIFEIIQSLYWTAFGLIDLTNLN
LEYDHQFTEFIGKLMLGSYCYISIIMLLNMFIAMMNTSYQIIAEKSDKEW
KFARSQLWISFFEEGGTTPVPFNIIPSPKSCKYFILILKHCLFCCSESHN
RSKWKSIRKLVKKVNEKEARHQIVMKDLIKRYLIQRQKAGENQGVTEDDL
NEIKGDISSFRFELIEIFKMNNMKTPAYTTLRNVTKLRHKGSKKGFNRIM
RKTNLPGNSNNVNNNIINNNNNNNLDNMIDKVSKFPNRSEIESTAKKKFP
VAFDNEGFQSSESDLQLPTPLTQIIITEEDDTNMRKMSTNFNDASQQPLN
VSRFLQDSNIYKRKPSFPSSGSKNDMKHAASADNVQNQTSQSPIGTKPLS
EHRRVDMV*

Aliases

The feature 'Short transient receptor potential channel 4' has the following synonyms


Synonym
trpc-2

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000017	photoreceptor neuron
PLANA:0000026	gut
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036770	Ankyrin_rpt-contain_sf
IPR002153	TRPC_channel
IPR002110	Ankyrin_rpt
IPR020683	Ankyrin_rpt-contain_dom
IPR005821	Ion_trans_dom
IPR013555	TRP_dom

Vocabulary: **biological process**
Term	Definition
GO:0070588	calcium ion transmembrane transport
GO:0006811	ion transport
GO:0055085	transmembrane transport
GO:0006810	transport
GO:0006816	calcium ion transport
GO:0006828	manganese ion transport
GO:0014051	gamma-aminobutyric acid secretion
GO:0048709	oligodendrocyte differentiation
GO:0051480	regulation of cytosolic calcium ion concentration
GO:0070509	calcium ion import

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0005901	caveola
GO:0005911	cell-cell junction
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0030863	cortical cytoskeleton
GO:0034704	calcium channel complex
GO:0043234	protein complex
GO:0045121	membrane raft

Vocabulary: **molecular function**
Term	Definition
GO:0005262	calcium channel activity
GO:0005515	protein binding
GO:0005216	ion channel activity
GO:0008013	beta-catenin binding
GO:0015279	store-operated calcium channel activity
GO:0045296	cadherin binding
GO:0070679	inositol 1,4,5 trisphosphate binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002153	Transient receptor potential channel, canonical	PRINTS	PR01097	TRNSRECEPTRP	coord: 689..702 score: 62.18 coord: 717..730 score: 73.53 coord: 667..688 score: 52.41
IPR002153	Transient receptor potential channel, canonical	PANTHER	PTHR10117	TRANSIENT RECEPTOR POTENTIAL CHANNEL	coord: 51..883
IPR002110	Ankyrin repeat	SMART	SM00248	ANK_2a	coord: 169..198 e-value: 0.084 score: 22.0 coord: 97..126 e-value: 5.1E-4 score: 29.3
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 97..124 score: 9.671
IPR005821	Ion transport domain	PFAM	PF00520	Ion_trans	coord: 413..696 e-value: 5.8E-24 score: 84.7
IPR020683	Ankyrin repeat-containing domain	PFAM	PF12796	Ank_2	coord: 71..146 e-value: 1.7E-6 score: 28.5
IPR020683	Ankyrin repeat-containing domain	PROSITE	PS50297	ANK_REP_REGION	coord: 90..201 score: 11.771
IPR036770	Ankyrin repeat-containing domain superfamily	GENE3D	G3DSA:1.25.40.20		coord: 40..311 e-value: 1.2E-18 score: 69.3
IPR036770	Ankyrin repeat-containing domain superfamily	SUPERFAMILY	SSF48403	Ankyrin repeat	coord: 69..193
IPR013555	Transient receptor ion channel domain	PFAM	PF08344	TRP_2	coord: 204..266 e-value: 3.1E-29 score: 101.0
None	No IPR available	TIGRFAM	TIGR00870	TIGR00870	coord: 51..813 e-value: 2.8E-215 score: 714.6
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..22
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..17
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 955..1008
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 955..997
None	No IPR available	PANTHER	PTHR10117:SF51	TRANSIENT RECEPTOR POTENTIAL PROTEIN	coord: 51..883
None	No IPR available	TMHMM	TMhelix		coord: 367..389
None	No IPR available	TMHMM	TMhelix		coord: 524..546
None	No IPR available	TMHMM	TMhelix		coord: 664..683
None	No IPR available	TMHMM	TMhelix		coord: 410..432
None	No IPR available	TMHMM	TMhelix		coord: 569..591
None	No IPR available	TMHMM	TMhelix		coord: 625..644
None	No IPR available	TMHMM	TMhelix		coord: 482..504

Main menu

Short transient receptor potential channel 4

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 10

Owlery

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