TNF receptor-associated factor

Query:   85 MSQSLSQIPTILELYEFNFPS------LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPS---KQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVE-HINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKLCSKKKLECPFHSLNC-----------NVDKMTKENL----------------MKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLT-----KELLDMNKKSSLS--VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            M+ +    P  LEL +  F        L  +  C  C+ +L+   Q  CG + C  C+ S L++GP+ C +   + I  E + +        DNA  +E+ SL   CP   C+ +  L+     H   C      C  C+  ++  +KE H +++C  R L C +C       D+K+ H      + C K+   C + C      +   ++H+K C K ++ C FH++ C           +  +  +E+L                  H   E +    +L  K    EN +  L  E+E   +       +  LD +K  +LS  V + + +I  LK  +     Q V        +  FIWK +DF  KR +A +GR  ++ S  FYTS +GYKMCLRIY  GDG G+GTHLS+FF +MKG  D LL WPF QKVTL ++DQ    +H  D F+PD  S+ +Q+PV++ NIASG P F  +S +   + Y ++D I++K  VD  G+
Sbjct:    1 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHH------EVCPKFPLTC-DGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSI-GLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN-NREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL 501          

Query:  145 SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKC--PFKLCSSEMPLRNMVEHI-NSCEFREISCNK--CQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKL----ECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSN------LISKIKDMENTIKNL--TDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            ++ D+ KC  C  +L + KQT CG + CE+C+ + L++    C +    C+  ++   + +  DN   +EI +L++ C    + C+ ++ L +++ H+ N C F E+ C +  C+ K+  KD   H +  C+ R+  C +C  ++    L+   L ++  +   K  +I      +H ++C  E +++  +K++    E     L   +D   ++  +K L++E      N      + S ++ ++N +  L   D+   Q      LL+    S LS      ++  ++        Q +E  S    N   IWK  D++ ++ +A  G+ +S+ S PFYT  FGYKMC R+Y  GDG+GKGTHLS+FF IM+GE+D LL WPFKQKVTL +MDQ +  +H  D FKPD  S+ ++KP  E NIASG P F+  + ++ N  Y K+DTI++K+ VDT  +  P
Sbjct:   46 TVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTA----CQESIV--KDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQVSLLQNESVE---KNKSIQ----SLHNQICSFE-IEIERQKEMLRNNESKILHLQRVIDSQAEK--LKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLE----SQLSRHDQMLSVHDIRLADMDLRFQVLETASY---NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTSDLPDP 485          

Query:  145 SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKC--PFKLCSSEMPLRNMVEHI-NSCEFREISCNK--CQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHT-----------------------------------KVCLKEHLKLCSKKKLECPFHSLNCNVD-KMTKENLMKHLNEEYVSHTSNLI----SKIKDMENTIK----------NLTDELENQKVLTKELLDMNK------------KSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            ++ D+ KC  C  +L + KQT CG + CE+C+ + L++    C +    C+  ++   + +  DN   +EI +L++ C    + C+ ++ L +++ H+ N C F E+ C +  C+ K+  KD   H +  C+ R+  C +C  ++    L+  H ++D    C      CP+ C V T                                   KV L ++  +   K ++   H+  C+ + ++ ++  M   NE  + H   +I     K+K+++  I+          ++   +E+ +    EL  ++K            +S LS      ++  ++        Q +E  S    N   IWK  D++ ++ +A  G+ +S+ S PFYT  FGYKMC R+Y  GDG+GKGTHLS+FF IM+GE+D LL WPFKQKVTL +MDQ +  +H  D FKPD  S+ ++KP  E NIASG P F+  + ++ N  Y K+DTI++K+ VDT  +  P
Sbjct:   46 TVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTA----CQESIV--KDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQK-HEDTD----CPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQ-SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASY---NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTSDLPDP 543          

Query:  145 SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKC--PFKLCSSEMPLRNMVEHI-NSCEFREISCNK--CQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHT-----------------------------------KVCLKEHLKLCSKKKLECPFHSLNCNVD-KMTKENLMKHLNEEYVSHTSNLI----SKIKDMENTIK----------NLTDELENQKVLTKELLDMNK------------KSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            ++ D+ KC  C  +L + KQT CG + CE+C+ + L++    C +    C+  ++   + +  DN   +EI +L++ C    + C+ ++ L +++ H+ N C F E+ C +  C+ K+  KD   H +  C+ R+  C +C  ++    L+  H ++D    C      CP+ C V T                                   KV L ++  +   K ++   H+  C+ + ++ ++  M   NE  + H   +I     K+K+++  I+          ++   +E+ +    EL  ++K            +S LS      ++  ++        Q +E  S    N   IWK  D++ ++ +A  G+ +S+ S PFYT  FGYKMC R+Y  GDG+GKGTHLS+FF IM+GE+D LL WPFKQKVTL +MDQ +  +H  D FKPD  S+ ++KP  E NIASG P F+  + ++ N  Y K+DTI++K+ VDT  +  P
Sbjct:   46 TVEDKYKCEKCHLVLCSPKQTECGHRFCESCMAALLSSSSPKCTA----CQESIV--KDKVFKDNCCKREILALQIYCRNESRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIALQK-HEDTD----CPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQ-SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASY---NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTSDLPDP 543          

Query:   88 SQSLSQIPTILELYEFNF-PSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKP-CPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCP-FKLCSSEMPLRNMVEHINSCEFREISCN--KCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYT--------------------AICP-------------------NNCDVHTKVCLKEHLKLCSKKKL----------------ECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNL---------ISKIKDMENTIKNLTDELENQK--------------VLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFR----NATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMN-NSLYCKNDTIYLKIAVD 1464
            S SL   P+I    E+ F   L +R KC  C  +L N  QT CG + C++CI S       P CP   +D E +     +++  DN   +E+ +L V C     C++++ L    +H+  C F+ + C+  KC+  +  KD + H    C+ RK KC YC      +D+  I+L +  E+ C +Y                     A+CP                    N   H    L+EH++L  +K +                E     L   + K+ KE   K   + +  + S L         I K   +E  +  L   +  Q+              V  K  L  N    L+VL+ +              +   E +  +      N   IWK TD++ K+ +A  G  VS+ S  FYTS  GY++C R Y  GDG G+G+HLS++F +M+GEFD LL WPF+Q+VTL ++DQ +G K+  +TFKPD  S+ +++P  E NIASG P+F+  S++ N  + Y K+DT++LK+AVD
Sbjct:   22 SISLDFEPSI----EYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICP---VDKEVIK---SQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCK-----KDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKE--FKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ-SGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVD 550          

Query:  166 CVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFK--LCSSEMPLRNMVEHINSCEFRE-ISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDF---CVKYTAICPNNCDV--HTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQ------EAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVD 1464
            C +C++ L++  + +C    C  C ++   N    C +    C+ ++    E    D A  K+I +L V C F+   C  +  L  + +H++ C F+  + C KC  +    D E H + KCE+ +  C +C    + RD       SDRE     C +    CP  C +    ++ ++ H   C      CPF    C      KE++ +HL++E V H   L  +I D++ T +          ++ +++   N + +  +L   ET     T+ F                   IWK    + +  +A+SG   ++ S PF +  FGYKM       GDG   G  +S++  ++KGEFD  L WPF + + +S++DQ           +  D  K  A      +P  E N A GS  F  L+++ N   Y K+D IY++I VD
Sbjct:   18 CPICEQALRDPIKLNCDHHYCRQCFEN--ENRTPGCAA----CQTII--QPELCQHDRAKQKQILALPVVCTFESSGCPWDGQLGTLHDHLSECTFKSSLKCEKCGRQFAKNDLEKH-RAKCELNRAVCSFC--NKTIRD-------SDRERHPKTCPQVIISCPFQCGLTDRPRLEIEAHCPSCPNVDNVCPFVPYGCTF-AGGKESIQQHLSDEPVRHLMYLCDEITDLKGTYE----------LMERDMGSFNDRQT-RILSAAETC----TEMF---------------GPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCSLAILQN---YVKDDKIYVQIDVD 412          

Query: 1093 SVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIM 1275
            S+ S PFY+  +GYKM     P GDG+    + SVF  +MKGE+DD+L WPF+  VT SI+
Sbjct:  182 SIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSIL 242          

Query:  370 VKCPFKLCSSEMPLRNMVEHIN-SCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVL-----KTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEA--GTKHHSDTFKPDARSACYQKPVDECN-IASGSPKFILLSLIMNNSLYCKNDTIYLKIAVD 1464
             +CP K C +++P   M +H+  +C  R   C  CQS+      E H+   C    + CE    +   R   ++H + D    C K    C +     +   L  H   C +  L CP     C+   + +  L  HL +E  S           +  + K      +  + + +  L+ N  + LS++     +  + I+ LK+        AV   S+ +   T +WK TD+ +K  +A     + + S PFYTS++GYK+   ++  G+G G+ TH+SV+  ++ GE+D LL WPF   +T ++ +Q A  G    +++F PD     +Q+P +E + +  G P+FI   L+ +   + K DT++L++ VD
Sbjct:  125 TQCPNK-CGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEHN-GSCGQEPVYCEAKCGQRILRGRMTLHKSKD----CAKRLRRCAHCQREFSADTLPLHAAQCPRAPLACP---QRCDAGPIPRGELEAHLRDECQSLA---------VSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMVALSSRQGQQIQMLKS--------AVSKLSINY-TGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRP-FIKGDTVFLRVKVD 470          

Query:  370 VKCPFKLCSSEMPLRNMVEHIN-SCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVL-----KTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEA--GTKHHSDTFKPDARSACYQKPVDECN-IASGSPKFILLSLIMNNSLYCKNDTIYLKIAVD 1464
             +CP K C +++P   M +H+  +C  R   C  CQS+      E H+   C    + CE    +   R   ++H + D    C K    C +     +   L  H   C +  L CP     C+   + +  L  HL +E  S           +  + K      +  + + +  L+ N  + LS++     +  + I+ LK+        AV   S+ +   T +WK TD+ +K  +A     + + S PFYTS++GYK+   ++  G+G G+ TH+SV+  ++ GE+D LL WPF   +T ++ +Q A  G    +++F PD     +Q+P +E + +  G P+FI   L+ +   + K DT++L++ VD
Sbjct:  134 TQCPNK-CGAQIPRIMMTDHLQYTCTMRRTRCEFCQSEFSGAGLEEHN-GSCGQEPVYCEAKCGQRILRGRMTLHKSKD----CAKRLRRCAHCQREFSADTLPLHAAQCPRAPLACP---QRCDAGPIPRGELEAHLRDECQSLA---------VSCSFKEAGCRFKGPRQMLEAHLESNAAAHLSLMVALSSRQGQQIQMLKS--------AVSKLSINY-TGTLLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRP-FIKGDTVFLRVKVD 479          

Query:  148 LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKL--CSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLR--IYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMN--NSLYCKNDTIYLKIAVDTL 1470
            L  R +C +C   L     TSCG + C +C+ +++    + CP      +N  L  + DI  DN T +EI  LK  CP     CS       +  H+ SC +R               ++   + KC   K+KC++     +                         N  + H K  +  H++L  +   +    +   +    +   +          H    +       N +     +   Q+++  E     +++ L  ++ Q  + + +    P            + N T +W+     +      +     V S   YTS  GYK C R  I P    V     LS+   +M+ E D  L WPFK ++ L ++     T    DT         + KP +   I++    F+  + I N     +C +D + +KI ++ +
Sbjct:   98 LDSRYECAICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQCCP-----MDNKRLSAEHDIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPYRR--------------QQEPQEEKCPFAKIKCDFVGRPET-------------------------NQLEEHLKADMPHHMQLMLQAFQQTAIATWQPHKPSTSGAAVEN-------GHGQQQLPPPPQYANGVDEQIVQTMYQRIVVLEQRTREQETRLENMQKQLRLARQQAPVDPR-----------YSNGTIVWRIEQLGALVARLRANANNQVYSHECYTSPHGYKFCARLNIQPRKPHV-----LSLHVHLMQSENDYHLDWPFKGRIKLCMVHPADATLSQHDTIMTKPEILAFHKPREA--ISTRGFGFLEYANISNIIQLGFCADDRLLIKIEINIV 475          

Query:  673 LKEHLKLCSKKKLECPFHSLNCNVDKMTKENLM---KHLNEEYVSHTSNLISKI-KDMENTIKN----------LTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTK-SFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAV 1461
            L E  KL ++   +  +H    N + +  E L+   + LN E        + +I +D++  + N          L  E++N K +  E  +   K   ++ +T + I  L+T+ +    I +V+N          IW+  D+ SK+++        + S  F    FGY + L IY  G G  KG ++     ++ GE+D LL+WP + +  + I DQ        D  K    +   +K  D+      +  F +   ++ +  Y +ND++++++ V
Sbjct:  185 LDEAQKLVNQLSADVTYHQNQLNDNILKLEELIFENERLNREKFFQIEEFLQQINEDIKTKLGNSDYVTSKQATLDYEVKNVKNIVCETEERCDKLDRALHQTMQNISDLETQMAMQQRIASVQNIR-----GHLIWRIKDY-SKKLEESKQYDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDYVK----TIFVRKKSDD--FIQSNQYFHIPHKVITSRNYLRNDSMFIEVRV 450          

Query:  673 LKEHLKLCSKKKLECPFHSLNCNVDKMTKENLM---KHLNEEYVSHTSNLISKI-KDMENTIKN----------LTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTK-SFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAV 1461
            L E  KL ++   +  +H    N + +  E L+   + LN E        + +I +D++  + N          L  E++N K +  E  +   K   ++ +T + I  L+T+ +    I +V+N          IW+  D+ SK+++        + S  F    FGY + L IY  G G  KG ++     ++ GE+D LL+WP + +  + I DQ        D  K    +   +K  D+      +  F +   ++ +  Y +ND++++++ V
Sbjct:  207 LDEAQKLVNQLSADVTYHQNQLNDNILKLEELIFENERLNREKFFQIEEFLQQINEDIKTKLGNSDYVTSKQATLDYEVKNVKNIVCETEERCDKLDRALHQTMQNISDLETQMAMQQRIASVQNIR-----GHLIWRIKDY-SKKLEESKQYDTILHSAMFSNKAFGYALRLDIYLNGKGTWKGRNMIACLNVLSGEYDPLLAWPCRLQAEIIIRDQCTNVADAEDYVK----TIFVRKKSDD--FIQSNQYFHIPHKVITSRNYLRNDSMFIEVRV 472          

Query:  145 SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDIN-----ADNATNKEIASLKVKCPFKLCSSEMPLRNMV-EHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKLCSKKKLECPFHSL-------NCNVDKMTKENLMKHLN-------------------EEYVS---------------------HTSNLISKIKDMENTIKNLTDELENQKVLTKEL-----LDMNKKSSLSVLKTQETIEKLKTK--SFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            S+  + +C  C+ IL+   Q  CG + C  C K   ++GP PC +     E +       +N      DNA  +EI SL  KCP + CS    L++   +H   C F  + C  CQ  +   +K+ H++ +CE R L C+YC    +F+++K+       ++ C K+   C  +C      +   +EH K C+K K  C F  +       NC   +  + ++M+HL                    +E V                          +  K+  +EN +  L  E+E   +  + +     LD  K  +LS  K ++    L T+        Q++        +  FIWK  +F  +R DA +GR  ++ S  FY+S++GYKMCLR+Y  GDG G+G+HLS+FF +MKG++D LL WPF QKVTL ++DQ    +H  D F+PD  S  +Q+P+ E NIASG P F  L+ +   S Y ++DTI++K  VD  G+
Sbjct:   38 SMEPKYQCQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPCEA--CRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQHEGRCAFERVKCEACQVLILLSEKDRHNERECEARTLNCKYCKVTFNFKEIKA------HDEICQKFPMQC-KDCGKKKIPREKFQEHTKSCAKSKSACQFREIGCRAVVDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIENLSN-KVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQN-NREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDLTGL 532          

Query:  145 SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDIN-----ADNATNKEIASLKVKCPFKLCSSEMPLRNMV-EHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKLCSKKKLECPFHSL-------NCNVDKMTKENLMKHLN-------------------EEYVS---------------------HTSNLISKIKDMENTIKNLTDELENQKVLTKEL-----LDMNKKSSLSVLKTQETIEKLKTK--SFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            S+  + +C  C+ IL+   Q  CG + C  C K   ++GP PC +     E +       +N      DNA  +EI SL  KCP + CS    L++   +H   C F  + C  CQ  +   +K+ H++ +CE R L C+YC    +F+++K+       ++ C K+   C  +C      +   +EH K C+K K  C F  +       NC   +  + ++M+HL                    +E V                          +  K+  +EN +  L  E+E   +  + +     LD  K  +LS  K ++    L T+        Q++        +  FIWK  +F  +R DA +GR  ++ S  FY+S++GYKMCLR+Y  GDG G+G+HLS+FF +MKG++D LL WPF QKVTL ++DQ    +H  D F+PD  S  +Q+P+ E NIASG P F  L+ +   S Y ++DTI++K  VD  G+
Sbjct:   38 SMEPKYQCQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPCEA--CRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQHEGRCAFERVKCEACQVLILLSEKDRHNERECEARTLNCKYCKVTFNFKEIKA------HDEICQKFPMQC-KDCGKKKIPREKFQEHTKSCAKSKSACQFREIGCRAVVDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIENLSN-KVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQN-NREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDLTGL 532          

Query:  145 SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDIN-----ADNATNKEIASLKVKCPFKLCSSEMPLRNMV-EHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKLCSKKKLECPFHSL-------NCNVDKMTKENLMKHLN-------------------EEYVS---------------------HTSNLISKIKDMENTIKNLTDELENQKVLTKEL-----LDMNKKSSLSVLKTQETIEKLKTK--SFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            S+  + +C  C+ IL+   Q  CG + C  C K   ++GP PC +     E +       +N      DNA  +EI SL  KCP + CS    L++   +H   C F  + C  CQ  +   +K+ H++ +CE R L C+YC    +F+++K+       ++ C K+   C  +C      +   +EH K C+K K  C F  +       NC   +  + ++M+HL                    +E V                          +  K+  +EN +  L  E+E   +  + +     LD  K  +LS  K ++    L T+        Q++        +  FIWK  +F  +R DA +GR  ++ S  FY+S++GYKMCLR+Y  GDG G+G+HLS+FF +MKG++D LL WPF QKVTL ++DQ    +H  D F+PD  S  +Q+P+ E NIASG P F  L+ +   S Y ++DTI++K  VD  G+
Sbjct:   51 SMEPKYQCQQCKDILRKPFQAQCGHRFCVFCFKQLTSSGPIPCEA--CRAEGIFEEETSVLNIAVAFPDNAARREIDSLPAKCPNEGCSWSGTLKDFENQHEGRCAFERVKCEACQVLILLSEKDRHNERECEARTLNCKYCKVTFNFKEIKA------HDEICQKFPMQC-KDCGKKKIPREKFQEHTKSCAKSKSACQFREIGCRAVVDNCKQQEHEQTSIMEHLRLMLALLSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVERSALTMEAISRQHRLDQEKIENLSN-KVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQN-NREHIIDAFRPDVSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDLTGL 545          

Query:  166 CVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKV------------------------------KCPFKLCSSEMPLRNMVEHINS-CEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCE-YCLEEMSFRDLKSIHLNSDREDFCVKYTAICP---NNCDV---------HTKVCLKEHLKLCSKK-----------------------KLECPFHSLNCNVDKMTKENLMKHLNEEYVS-------HTSNLIS---------KIKDMENTIKNLTDELENQKVLTKELLD--MNKKSSLSVLKTQE----------TIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            C  C+ +L N +QT CG + CE+CI   L+     CP+      +++   ++ I  D   N+EI +LKV                               CP   C  +M  ++M EH++  C+ RE++C  C  K+   + + H +  C    + C  +C    SF  +    L+S + D C K    C      C           H      EHL++ + +                        L      +    ++M ++N  + L ++ VS       H+  L+           ++ M   ++ L   +E+ + +   L    +N  S    L + E          ++  ++       +Q +E  S    N T IWK  D++ ++ +A   + +S+ S PFYT  FGYKMC R+Y  GDG+GKGTHLS+FF +M+GE+D LL WPFKQKVTL +MDQ    KH  D FKPD  S+ +++P  E NIASG P F+  + ++ N  Y K+DTI++K+ VDT  +  P
Sbjct:   56 CETCRLVLCNPRQTECGHRFCESCINELLSKPNPVCPA------DLLPLFEDKIFRDVCCNREIMALKVYCRSEKNGCKEQMCLQQVMEHLVICPYFEVPCPLGKCKEKMMRKDMPEHLSRKCKHREVTCEFCSLKMALTELQKHKETVCPAFPVACPNHC----SFSSILRSELSSHQHD-CPKAQVTCSFIRYGCSYKGLNQEMREHESSFASEHLRMMAVRNTTLEAKVEDVKSELMERYKVLPSLSSRLAEVERQYEEMREKN--RQLEQKLVSMQMLMSSHSEKLLEVEMELRELRPLRAMREEVETLRGSVESMRSMVSSLDSSCVNSASGSHTLASLEQQLTRHDDLMSVHDVRLAEMDLKLQVLETASF---NGTLIWKIRDYKRRKQEAVVSKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLQWPFKQKVTLMLMDQGPARKHLGDAFKPDPSSSSFRRPTGEMNIASGCPLFVAQT-VLENGTYIKDDTIFIKVTVDTSDLPDP 573          

Query: 1021 NATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            +  F+WK +DF  KR DA +GR  ++ S  FYTS++GYKMCLRIY  GDG G+GTHLS+FF +M+G  D LL WPF QKVTL ++DQ    +H  D F+PD  S+ +Q+PV + NIASG P F  LS + + + Y ++DTI++K  VD  G+
Sbjct:  125 DGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQN-NREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVDLTGL 275          

Query:  148 LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKC--PFKLCSSEMPLRNMVEHINS-CEFREISCNK--CQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHT--KVCLKEHL-------KLCSKKKLECPFHSLNCNVDKMTKENLMKHL---------------------------------------------------NEEYVSHTSNLIS----KIKDMENTIKNL---TDELENQKVLTKEL------LDMNKKSSLS----VLKTQ-------ETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            + ++ KC  C+ +L N +QT CG + CE C+ + L++    C    + CE+ +    + +  DN   +E+ +L++ C    + C   + L N++ H+ S C+F E+SC +  C+ K+  KD   H +  C+ R+  C++C  ++   +++  H + D    C      CP+ C V +  +  L  HL         CS K+  C F   N  +      + ++H+                                                   NE  +     +I     K+KD++  I+NL    DE +  K   + L      L++  K++ S    VL+TQ        ++  ++        Q +E  S    N   IWK  D++ ++ +A  G+ +S+ S PFYT  FGYKMC R+Y  GDG+GKGTHLS+FF IM+GE+D LL WPFKQKV+L +MDQ    +H  D FKPD  S+ ++KP  E NIASG P F+  + ++ N  Y K+DTI++K+ VDT  +  P
Sbjct:   42 VEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQC----MACEDNI--TKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQK-HEDVD----CPSVVISCPHMCSVKSLLRSELNAHLLECVNAPSTCSFKRYGCTFKGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRNNEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASY---NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTSDLPDP 561          

Query:  148 LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKC--PFKLCSSEMPLRNMVEHINS-CEFREISCNK--CQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDV---------------HTKVCLKEHLKL-------------------CSKKKLECPFHSLNCNVD---KMTKENLMKHLNEEYVSHTSNLIS----KIKDMENTIKNL---TDELENQKVLTKEL------LDMNKKSSLS----VLKTQ-------ETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            + ++ KC  C+ +L N +QT CG + CE C+ + L++    C    + CE+ +    + +  DN   +E+ +L++ C    + C   + L N++ H+ S C+F E+SC +  C+ K+  KD   H +  C+ R+  C++C  ++   +++  H + D    C      CP+ C V               H      +H+ L                     K K     H+  C+ +   +  KE L    NE  +     +I     K+KD++  I+NL    DE +  K   + L      L++  K++ S    VL+TQ        ++  ++        Q +E  S    N   IWK  D++ ++ +A  G+ +S+ S PFYT  FGYKMC R+Y  GDG+GKGTHLS+FF IM+GE+D LL WPFKQKV+L +MDQ    +H  D FKPD  S+ ++KP  E NIASG P F+  + ++ N  Y K+DTI++K+ VDT  +  P
Sbjct:   42 VEEKYKCEKCRLVLCNPRQTECGHRFCETCMNAILSSTSPQC----MACEDNI--TKDKVFKDNCCRREVLALQMFCRNETRGCKELITLGNLLIHLKSDCQFEELSCPRADCKEKVIRKDLSDHIEKTCKYRETPCKFCRNQVPLVEMQK-HEDVD----CPSVVISCPHMCSVKSLLRSEGTNQQIKAHEASSAVQHVNLMKEWSNYLEAKVSMLQNESSEKNKSIQILHNQMCSFEIEIERHKEQLRN--NEARIIQLQRVIEGQADKLKDLDKEIRNLRQTGDEADGMKSNYESLQNRLSQLEVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASY---NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMDQGPSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTSDLPDP 536          

Query:   82 SMSQSLSQIPTILELYEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKP-CPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFK-LCSSEMPLRNMVEHINSCEFREISC--NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCV----KYTAICPN----------NCDV---------HTKVCLKEHL--KLCSKKKLECPFHSLNCNVDKMTKENLMKHLNE-------------EYVSHTSNLISKIKDMENTI-KNLTDELENQKVLTKELLDMNKKSSLSVLKTQE----TIE-----------------------KLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMN--NSLYCKNDTIYLKIAVD 1464
            S + SL  +P    L+      L DR KC  C  +L N  QT CG + CE CI + +     P CP   ID EN+  H   +I  DN   +E+ +L V C     C  ++ L    EH+  C +    C  + C  ++  K+ + H +++C++R+  C YC + MSF      H N+ ++ F      K+   CP            C+V         H    L++H+   L    KLE    S+  N+D   KE+ ++ L++             ++     N +S  K + + I K++  E +  ++++KE   ++ +  L  L++ +    T+E                       K++  S     + VE  S    N   IWK TD+E K+ +A  GR VS+ S  FYTS  GY++C R Y  GDG GKG+ LS++F +MKGEFD +L WPFKQKVTL ++DQ     H +D F+ D  S+ +++P  E NIASG P+F   + + N  N  Y K+DT+++KI VD
Sbjct:   19 SAAVSLDFVPKQEYLF---VEQLQDRYKCASCHLVLHNPHQTGCGHRFCEKCISNLIELSETPQCP---IDMENIKSH---EIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMSFN-----HENNYKKIFFSFQLDKHLCECPEAELQCTFSNYGCNVMVKRGKVKEHEDTFLRDHMLYVLNRNMKLEEQVLSVLQNLD--LKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTSY---NGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRADPNSSSFKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIKIVVD 532          

Query:  148 LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKP-CPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFK-LCSSEMPLRNMVEHINSCEFREISC--NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCD-VHTKVCLKEHLKLCSKKKLECPFHSLNC------------------------------NVDKMTKENLMKHLNE-------------EYVSHTSNLISKIKDMENTI-KNLTDELENQKVLTKELLDMNKKSSLSVLKTQE----TIE-----------------------KLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMN--NSLYCKNDTIYLKIAVD 1464
            L DR KC  C  +L N  QT CG + CE CI + +     P CP   ID EN+  H   +I  DN   +E+ +L V C     C  ++ L    EH+  C +    C  + C  ++  K+ + H +++C++R+  C YC + MS                C+ Y   C NN   +     L +HL  C + +L+C F +  C                              N+D   KE+ ++ L++             ++     N +S  K + + I K++  E +  ++++KE   ++ +  L  L++ +    T+E                       K++  S     + VE  S    N   IWK TD+E K+ +A  GR VS+ S  FYTS  GY++C R Y  GDG GKG+ LS++F +MKGEFD +L WPFKQKVTL ++DQ     H +D F+ D  S+ +++P  E NIASG P+F   + + N  N  Y K+DT+++KI VD
Sbjct:   38 LQDRYKCASCHLVLHNPHQTGCGHRFCEKCISNLIELSETPQCP---IDMENIKSH---EIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMSLCLA------------CLDYMFSCRNNYKKIFFSFQLDKHLCECPEAELQCTFSNYGCNVMVLYHSLSVHFLYLCTFTSVSQVLGLQQNLD--LKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSMWLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHKMQMTSNEERFRLVEGTSY---NGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRADPNSSSFKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIKIVVD 531          

Query:  166 CVLCQRILKNAKQTSCGCKACENC---IKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSN------------LISKIKDM--------------ENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            C  C+ +L+   Q  CG + C +C   I  ++A      P     CE             + T   I+                    V H   C +    C  C++ ++A +++ H + +C  RKL C YC     F D+K+       ++ C K+   C   C        K  L +C    + C + ++ C  + +  +  ++H N+    H +               +K+ +M              EN +  L  E+E      +EL    + +   + +T    E L      T +Q  E  +    +  FIWK ++F  KR DA +GR  ++ S PFYT+++GYKMCLRIY  GDG G+ THLS+FF +MKG  D LL WPF QKVTL ++DQ    +H  D F+PD  S+ +Q+P+ E NIASG P F  +S +   + Y ++DTI++K+ VD  G+
Sbjct:   37 CSDCKNLLRRPLQAQCGHRYCSHCLNKIIRWVARNWGGVPECPAVCER-----------SDWTGALIS--------------------VGHEGKCPYLLAPCPACKTIIRAANRDLHSERECPERKLNCRYCKLSFYFPDIKA------HDEICPKFPMTC-EGCGRKKIPREKVRLFVC----MPCRYAAVGC-TEMVENDKCLEHENKSLAEHLAKGSPAPPANAPPNNSAKVAEMLLKFDTLDKKNTTFENIVSVLNREVERSSHAAEELARQLRAADTRLERTLGQKE-LIVAELETRMQESELSTY---DGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQN-NREHVIDAFRPDVSSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIVDLTGL 454          

Query:   85 MSQSLSQIPTILELYEFNFPS--LSDRLK----CVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPS---KQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVE-HINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLIS----------------------------KIKDMENTIKNLTDELENQKVLT-----KELLDMNKKSSLS--VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            M+ +    P  LEL +  F    L  RL+    C  C+ IL+   Q  CG + C  C+ S L++GP+ C +   + +  E + +        DNA  +E+ SL   CP   C+ +  L+     H   C F    C  C+  ++  +KE H + +C  R L C++C    S  DL+ +H      + C K+   C + C      +   ++H++ CSK ++ C FH++ C+ + +  ENL  H  +    H + L+S                            KI   EN +  L  E+E   V       +  LD +K  +LS  V + + +I  LK  +     Q V    V   +  FIWK +DF  KR +A +GR  ++ S  FYTS +GYKMCLR+Y  GDG G+GTHLS+FF +MKG  D LL WPF QKVTL ++D     +H  D F+PD  S+ +Q+PV + NIASG P F  +S +   + Y ++D I++K  VD  G+
Sbjct:    1 MAAASVTSPGSLELLQPGFSKTLLGTRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLE-VHY-----EVCPKFPLTC-DGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCS-EMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSI-GLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHN-NREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL 501          

Query:  127 YEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKP-CPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCP-FKLCSSEMPLRNMVEHINSCEFREISC--NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHT--KVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKH------------LNEEY-------------------------VSHTSNLISKIKDM-----ENTIKNLTDELENQKVLTKELLDM--NKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNAT--------------------------------FIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNN-SLYCKNDTIYLKIAVD 1464
            Y+F    L +R KC  C  +L N  QT CG + C+ CI+S       P CP   +D E +     +++  DN   +E+ +L V C     C++ + L    +H+  C F+ + C    C+  +  KD + H    C  R+ KC YC      RD+   +L    E+ C  Y   CPN C V T  +  + EHL +C + + +CPF    C V K  + NL++H            L + Y                         + H +N +S+ +D+        + + TD+    +   ++LL +   + S L +    + ++ +K +   T ++A + + V+    T                                 IWK TD+  K+ +A  G  VSV S PFYTS  GY++C R Y  GDG GKGTHLS++F +M+GEFD LL WPF+Q+VTL ++DQ     H  +TFK D  S+ +++P  E NIASG P+F+  S + N+ + Y K+DT++LK+AVD
Sbjct:   33 YQF-VEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICP---VDKEVIK---PQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCK-----RDIVVTNLQDHEENSCPAYPVSCPNRC-VQTIPRARVNEHLTVCPEAEQDCPFKHYGCTV-KGKRGNLLEHERAALQDHMLLVLEKNYQLEQRVNALLSSLERKKKMAAADSAIQHATNPMSRFQDIFSFLYRKALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRI--TQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVD 545          

Query:  127 YEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKP-CPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCP-FKLCSSEMPLRNMVEHINSCEFREISC--NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHT--KVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKH------------LNEEY-------------------------VSHTSNLISKIKDM-----ENTIKNLTDELENQKVLTKELLDM--NKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNAT--------------------------------FIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNN-SLYCKNDTIYLKIAVD 1464
            Y+F    L +R KC  C  +L N  QT CG + C+ CI+S       P CP   +D E +     +++  DN   +E+ +L V C     C++ + L    +H+  C F+ + C    C+  +  KD + H    C  R+ KC YC      RD+   +L    E+ C  Y   CPN C V T  +  + EHL +C + + +CPF    C V K  + NL++H            L + Y                         + H +N +S+ +D+        + + TD+    +   ++LL +   + S L +    + ++ +K +   T ++A + + V+    T                                 IWK TD+  K+ +A  G  VSV S PFYTS  GY++C R Y  GDG GKGTHLS++F +M+GEFD LL WPF+Q+VTL ++DQ     H  +TFK D  S+ +++P  E NIASG P+F+  S + N+ + Y K+DT++LK+AVD
Sbjct:   33 YQF-VEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICP---VDKEVIK---PQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCK-----RDIVVTNLQDHEENSCPAYPVSCPNRC-VQTIPRARVNEHLTVCPEAEQDCPFKHYGCTV-KGKRGNLLEHERAALQDHMLLVLEKNYQLEQRVNALLSSLERKKKMAAADSAIQHATNPMSRFQDIFSFLYRKALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRI--TQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVD 545          

Query:   85 MSQSLSQIPTILELYEFNFPS--LSDRLK----CVLCQRILKNAKQTSCGCKACENCIKSYL-------ANGPKPCPS---KQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVE-HINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLIS----------------------------KIKDMENTIKNLTDELENQKVLT-----KELLDMNKKSSLS--VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            M+ +    P  LEL +  F    L  RL+    C  C+ IL+   Q  CG + C  C+ S L       ++GP+ C +   + +  E + +        DNA  +E+ SL   CP   C+ +  L+     H   C F    C  C+  ++  +KE H + +C  R L C++C    S  DL+ +H      + C K+   C + C      +   ++H++ CSK ++ C FH++ C+ + +  ENL  H  +    H + L+S                            KI   EN +  L  E+E   V       +  LD +K  +LS  V + + +I  LK  +     Q V    V   +  FIWK +DF  KR +A +GR  ++ S  FYTS +GYKMCLR+Y  GDG G+GTHLS+FF +MKG  D LL WPF QKVTL ++D     +H  D F+PD  S+ +Q+PV + NIASG P F  +S +   + Y ++D I++K  VD  G+
Sbjct:    1 MAAASVTSPGSLELLQPGFSKTLLGTRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILRCASILSSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLE-VHY-----EVCPKFPLTC-DGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCS-EMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSI-GLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHN-NREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL 508          

Query:  145 SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKC--PFKLCSSEMPLRNMVEHI-NSCEFREISCNK--CQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHT-----------------------------------KVCLKEHLKLCSKKKLECPFHSLNCNVD-KMTKENLMKHLNEEYVSHTSNLI----SKIKDMENTIK----------NLTDELENQKVLTKELLDMNK------------KSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            ++ D+ KC  C+ +L N KQT CG + CE+C+ + L++    C +    C+  ++   + +  DN   +EI +L+V C    + C+ ++ L +++ H+ N C+F E+ C +  C+ K+  KD   H +  C+ R+  C +C  ++    L+  H ++D    C      CP+ C V T                                   KV L ++  +   K ++   H+  C+ + ++ ++  M   NE  + H   +I     K+K+++  I+          ++   +E+ +    EL  ++K            +S LS      ++  ++        Q +E  S    N   IWK  D++ ++ +A  G+ +S+ S PFYT  FGYKMC R+Y  GDG+GKGTHLS+FF IM+GE+D LL WPFKQKVTL +MDQ +  +H  D FKPD  S+ ++KP  E NIASG P F+  + ++ N  Y K+DTI++K+ VDT  +  P
Sbjct:   45 TVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTA----CQESII--KDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQK-HEDTD----CPCVVVSCPHKCSVQTLLRSEGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQ-SLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASY---NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTSDLPDP 542          

Query:   85 MSQSLSQIPTILELYEFNFPS--LSDRLK----CVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPS---KQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVE-HINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLIS----------------------------KIKDMENTIKNLTDELENQKVLT-----KELLDMNKKSSLS--VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            M+ +    P  LEL +  F    L  RL+    C  C+ IL+   Q  CG + C  C+ S L++GP+ C +   + +  E + +        DNA  +E+ SL   CP   C+ +  L+     H   C F    C  C+  ++  +KE H + +C  R L C++C    S  DL+ +H      + C K+   C + C      +   ++H++ CSK ++ C FH++ C+ + +  ENL  H  +    H + L+S                            KI   EN +  L  E+E   V       +  LD +K  +LS  V + + +I  LK  +     Q V    V   +  FIWK +DF  KR +A +GR  ++ S  FYTS +GYKMCLR+Y  GDG G+GTHLS+FF +MKG  D LL WPF QKVTL ++D     +H  D F+PD  S+ +Q+PV + NIASG P F  +S +   + Y ++D I++K  VD  G+
Sbjct:    1 MAAASVTSPGSLELLQPGFSKTLLGTRLEAKYLCSACKNILRRPFQAQCGHRYCSFCLTSILSSGPQNCAACVYEGLYEEGISILESSSAFPDNAARREVESLPAVCPNDGCTWKGTLKEYESCHEGLCPFLLTECPACKGLVRLSEKEHHTEQECPKRSLSCQHCRAPCSHVDLE-VHY-----EVCPKFPLTC-DGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCS-EMVETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQKIATFENIVCVLNREVERVAVTAEACSRQHRLDQDKIEALSNKVQQLERSI-GLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDHN-NREHVIDAFRPDVTSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL 501          

Query:  127 YEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKP-CPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCP-FKLCSSEMPLRNMVEHINSCEFREISC--NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHT--KVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSH--------------TSNLI-------SKIKDMENTIKNLTDELE--------------NQKVLTKE-----LLDMNKKSSLSVLKTQETIEKLKT--------KSFPTPIQAVENKSVIFRNAT--------------------------------FIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNN-SLYCKNDTIYLKIAVD 1464
            Y+F    L +R KC  C  +L N  QT CG + C+ CI+S       P CP   +D E +     +++  DN   +E+ +L V C     C++ + L    +H+  C F+ + C    C+  +  KD + H    C  R+ KC YC      RD+   +L    E+ C  Y   CPN C V T  +  + EHL +C + + +CPF    C V K  + NL++H       H               S+L        SKI+ +  T+K    EL+              N + LT        L+   +  L ++  Q +   L++        K   T ++A + + V+    T                                 IWK TD+  K+ +A  G  VSV S PFYTS  GY++C R Y  GDG GKGTHLS++F +M+GEFD LL WPF+Q+VTL ++DQ     H  +TFK D  S+ +++P  E NIASG P+F+  S + N+ + Y K+DT++LK+AVD
Sbjct:   33 YQF-VEQLEERYKCAFCHSVLHNPHQTGCGHRFCQQCIRSLRELNSVPICP---VDKEVIK---PQEVFKDNCCKREVLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNESCREAMLRKDVKEHLSAYCRFREEKCLYCK-----RDIVVTNLQDHEENSCPAYPVSCPNRC-VQTIPRARVNEHLTVCPEAEQDCPFKHYGCTV-KGKRGNLLEHERAALQDHMLLVLEKNYQLEQRISDLYQSLEQKESKIQQLAETVKKFEKELKQFTQMFGRNGTFLSNVQALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVD 551          

Query:   85 MSQSLSQIPTILELYEFNFPS------LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPS---KQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVE-HINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKLCSKKKLECPFHSLNC-----------NVDKMTKENL----------------MKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLT-----KELLDMNKKSSLS--VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            M+ +    P  LEL +  F        L  +  C  C+ +L+   Q  CG + C  C+ S L++GP+ C +   + I  E + +        DNA  +E+ SL   CP   C+ +  L+     H   C      C  C+  ++  +KE H +++C  R L C +C       D+K+ H      + C K+   C + C      +   ++H+K C K ++ C FH++ C           +  +  +E+L                  H   E +    +L  K    EN +  L  E+E   +       +  LD +K  +LS  V + + +I  LK  +     Q V        +  FIWK +DF  KR +A +GR  ++ S  FYTS +GYKMCLRIY  GDG G+GTHLS+FF +MKG  D LL WPF QKVTL ++DQ    +H  D F+PD  S+ +Q+PV++ NIASG P F  +S +   + Y ++D I++K  VD  G+
Sbjct:    1 MAAASVTPPGSLELLQPGFSKTLLGTKLEAKYLCSACRNVLRRPFQAQCGHRYCSFCLASILSSGPQNCAACVHEGIYEEGISILESSSAFPDNAARREVESLPAVCPSDGCTWKGTLKEYESCHEGRCPLMLTECPACKGLVRLGEKERHLEHECPERSLSCRHCRAPCCGADVKAHH------EVCPKFPLTC-DGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLETVEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKTATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSI-GLKDLAMADLEQKVLEMEASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN-NREHVIDAFRPDVTSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL 501          

Query:  145 SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKC--PFKLCSSEMPLRNMVEHIN------------------------------SCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEY-CLEEMSFRDLKSIHLNSDREDFCVKYTAICP------------NNCDVHTKVCLKEHLKL-------------------CSKKKLECPFHSLNCNVD-KMTKENLMKHLNEEYVSHTSNLI----SKIKDMENTIK----------NLTDELENQKVLTKELLDMNK------------KSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            ++ D+ KC  C+ +L N KQT CG + CE+C+ + L++    C +    C+  ++   + +  DN   +EI +L+V C    + C+ ++ L +++ H+                               +C++RE +C+ C+S++     + H+   C    + C + C  +   R   S HL+      CV   + C                  H      +H+ L                     K K     H+  C+ + ++ ++  M   NE  + H   +I     K+K+++  I+          ++   +E+ +    EL  ++K            +S LS      ++  ++        Q +E  S    N   IWK  D++ ++ +A  G+ +S+ S PFYT  FGYKMC R+Y  GDG+GKGTHLS+FF IM+GE+D LL WPFKQKVTL +MDQ +  +H  D FKPD  S+ ++KP  E NIASG P F+  + ++ N  Y K+DTI++K+ VDT  +  P
Sbjct:   45 TVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTA----CQESII--KDKVFKDNCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKDLRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSE-----CVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASY---NGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQT-VLENGTYIKDDTIFIKVIVDTSDLPDP 567          

Query:   88 SQSLSQIPTILELYEFNF-PSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKP-CPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCP-FKLCSSEMPLRNMVEHINSCEFREISCN--KCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYT--------------------AICP-------------------NNCDVHTKVCLKEHLKLCSKKKL----------------ECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNL---------ISKIKDMENTIKNLTDELENQK--------------VLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFR----NATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMN-NSLYCKNDTIYLKIAVD 1464
            S SL   P+I    E+ F   L +R KC  C  +L N  QT CG + C++CI S       P CP   +D E +     +++  DN   +E+ +L V C     C++++ L    +H+  C F+ + C+  KC+  +  KD + H    C+ RK KC YC      +D+  I+L +  E+ C +Y                     A+CP                    N   H    L+EH++L  +K +                E     L   + K+ KE   K   + +  + S L         I K   +E  +  L   +  Q+              V  K  L  N    L+VL+ +              +   E +  +      N   IWK TD++ K+ +A  G  VS+ S  FYTS  GY++C R Y  GDG G+G+HLS++F +M+GEFD LL WPF+Q+VTL ++DQ +G K+  +TFKPD  S+ +++P  E NIASG P+F+  S++ N  + Y K+DT++LK+AVD
Sbjct:   22 SISLDFEPSI----EYQFVERLEERYKCAFCHSVLHNPHQTGCGHRFCQHCILSLRELNTVPICP---VDKEVIK---SQEVFKDNCCKREVLNLYVYCSNAPGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCK-----KDVVVINLQNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKE--FKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ-SGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVD 550          

Query:  418 MVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            MVEHI SC+ REI+C KC  K  AK+K +HDK+KCEMR + C+YC   M  +DL  IHLN DR++ C KY  IC NNC+   KV LK+HLK+C  KKLECPFH  +C +DKMTKE LMKHL+EEY +HTS+LI+K+KD+E+ I +L  EL NQ ++TKEL +MNKKSS S LK ++TIE+LK K+  T IQ ++NK+VIFRNA+FIWKFTDFE +R+DAESG +VSVTSD FYTSEFGYKMCLR+YPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSI+DQE+G+K HSDTFKPDARSACYQKP DECNIASG PKFILLSLIMNNS+YCKNDTI+LKIAVDT+GI KP
Sbjct:    1 MVEHIESCDLREITCEKCGIKFGAKEKANHDKDKCEMRMVNCDYCGITMKSKDLNIIHLNPDRDELCSKYVGICSNNCNETRKVNLKDHLKICPNKKLECPFHQFDCKIDKMTKEKLMKHLDEEYFNHTSSLINKVKDLESKIIDLESELHNQILITKELFEMNKKSSESRLKIEKTIEELKKKAPATSIQTIDNKNVIFRNASFIWKFTDFEVRRVDAESGGRVSVTSDAFYTSEFGYKMCLRVYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSILDQESGSKPHSDTFKPDARSACYQKPTDECNIASGFPKFILLSLIMNNSIYCKNDTIFLKIAVDTMGIFKP 356          

Query:   85 MSQSLSQIPTILELY-EFNFP-SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKL--KTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAV 1461
            MS   S +PT ++ Y + +FP ++SD LKC++C ++L  A QT CGC+ C+ C+K Y A G   C +    C ++      +I  DNA N+EI  L VKC F  C     L+++ +H++SC  + I+C  C  +L   + + H + KC MR + C +C EEM + +L  +HLN   E  C K    CP  CD   +V L +H K CSKK + C F  + CN   MTKE+L+KH NEE + H+  L+ +I  M+N I  L  +     +L  E      K    +L   +++EK+   T    + +++ E K+V +RN  FIWK   F   + +AE G ++S+TSD FYT EFGYKM ++IYPAGDGVGKGTHLSVFF +M+GEFDDLL WPFK KVTL+I+DQ+  T  HSDTFKPD RS CYQ+P D+ NIASGSPKFI  S +         D IYL   +
Sbjct:    1 MSLLNSNLPTNIKRYRKKHFPFNISDNLKCIICSQLLLEALQTDCGCRYCKECLKEYQAKGKTKCLTD--GCGDL-----GNIIPDNAVNREIGKLTVKCLFPGCEHSELLKDIGDHLDSCIHQTINCKSCNEELTKIELKEHTEKKCPMRLVSCTHCGEEMEYSNLTELHLNVHTEKLCAKLVGKCPYKCDNGKEVNLLDHRKSCSKKPVTCLFSEIGCN-RVMTKEDLIKHNNEESLQHSRLLMKEIITMKNDISELKMKTLEFNILKIEF----SKFQSEILDKIKSLEKIPRHTSPSTSSVRSSEEKTV-YRNGVFIWKIERFSELKSEAERGNRISITSDYFYTKEFGYKMSMKIYPAGDGVGKGTHLSVFFTLMRGEFDDLLQWPFKNKVTLTILDQKNKTNDHSDTFKPDVRSTCYQQPTDDYNIASGSPKFITFSQL---------DEIYLXXXI 441          

Query:  112 TILELYEFN--FPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAV 1461
            T L+LY+ N    +++D LKCV+CQ IL +A QT CGC+ C+ CI +YL NG K C ++  DC +V+         D ATNKEI+ LKVKC ++ C  E  L+++  H++ CE+R   C+ C  +   K++ +H  N+C +R++ C+YC   ++F++    HL  +  D C KY AICP  C   +KV L  H K C  K LECP H  +C    + K+ + +HLN     HT  ++++++ +E   K++ + + N  +   +LL    K++L V+K  +  +   + S  T ++   NK+ IFRN  ++WK   F   R +A  G+  ++ S+ FYTS+FGYKMC++IYP GDGVGKGTHLS+FF IMKG++DD+L WPFK KV ++I D  + + + SDTFKPD +S CYQ+P +E NIASGSPKFI  S + N   + K DT+Y++I V
Sbjct:   11 TALKLYKDNKWRFTINDNLKCVMCQDILLDAIQTDCGCRYCKECIDNYLENGEKECVAEYEDCRSVI----TSYIYDRATNKEISLLKVKCLYEGCVFEDTLKSIKGHLDFCEYRNEMCSLCGMEYIIKEESNHLANECLLREVLCQYCRTLLTFKEYNESHLCFESRDLCGKYEAICPYGCTGESKVNLLHHRKSCENKPLECPLHVFDCK-QLIPKDQMTEHLNTSSYEHTLTIVTELRKLEKQNKHMEERM-NILIEENQLL----KATLEVMKL-DLPKNSGSISRDTSLKRA-NKT-IFRNGKYMWKIKSFSKLRENAMRGKNPTILSEAFYTSDFGYKMCMKIYPCGDGVGKGTHLSIFFVIMKGDYDDILPWPFKNKVIITIFDDFSKSTNLSDTFKPDPKSICYQRPEEEYNIASGSPKFISFSELKN---FLKKDTLYIQINV 446          

Query:  145 SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDC----ENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNM-VEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEE--YVSHTSNLIS-KIKDMENTIKNLTDELENQKVLTKEL-----LDMNKKSSLSV-LKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            S+  + +C  C+ +L+   Q  CG + C  C K   ++GP PC + + +     +  ML++ E    DNA  +EI SL  KCP + CS    L++   +H   CEF  ++C  CQ  +   D++ H++ +CE R L C+YC    +F+D+K+       ++ C K+   C  +C      +   +EH K C+K K  C F  + C   +   +N  +H +E+     H   +++ K+  +EN    L  E+E   +  + L     LD  K  SLS  ++  E    ++        Q++        +  FIWK +DF  +R DA +GR  ++ S  FY+S++GYKMCLR+Y  GDG G+ THLS+FF +M+G++D LL WPF QKVTL ++DQ    +H  D F+PD  S  +Q+P+ E NIASG P F  L+ +   S Y ++DTI++K  VD  G+
Sbjct:   35 SMEPKYQCQQCKEVLRKPFQAQCGHRFCVFCFKELTSSGPIPCEACRAEGIFEEQLSMLNITEAF-PDNAARREIDSLPAKCPNEGCSWTGTLKDYEGQHEGRCEFERVTCEACQVLILLSDRDRHNERECEARTLNCKYCKVSFNFKDIKA------HDEICQKFPMQC-KDCGKKKIPREKFQEHSKSCAKSKSACQFREIGC---RAVVDNGKQHEHEQASITEHLRLMLADKMTALENIACVLNREVERTALTLEALTRQHRLDQEKIESLSTKVRQLERTLTMRDLKLAESEQSLRELQFCTYDGMFIWKISDFSHRRQDALAGRSPALFSPAFYSSKYGYKMCLRLYMNGDGTGRNTHLSLFFVVMRGKYDALLKWPFGQKVTLMLLDQN-NREHIIDAFRPDTSSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDLTGL 482          

Query:   82 SMSQSLSQIP-TILELYEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPS---KQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNM-VEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKE----HLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKEL-----LDMNKKSSLS-VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            S+  SL  IP ++L +      S+  + +C  C ++L+   Q  CG + C +C+K   ++GPKPC +   ++I  E   +    +   DNA  +EIASL  KC  + CS    ++    +H   CE+  + C  CQ  +   +KE H++ +CE R L C+YC    +F+++K+       ++ C K+   C    D   K   +E    H K C+K K  CPF  + C V     + +  +    ++   S ++ +++ +EN +  L  E+E   +  +       LD +K  +LS  ++  E    ++        Q +        +  F+WK  DF  +R DA +GR  ++ S  FY+S++GYKMCLR+Y  GDG G+GTHLS+FF +M+G+ D LL WPF QKVTL ++DQ    +H  D F+PD  S  +Q+P+ E NIASG P F  L+ +   S Y ++DTI++K  VD  G+
Sbjct:    8 SLESSLPGIPQSVLAV------SMETKYQCQQCHQVLRKPVQAQCGHRFCVHCLKLLTSSGPKPCEACRQEEIYEEPQSILNSNEAFPDNAAGREIASLPAKCISEGCSWTGCIKEYEAQHEGKCEYERVPCETCQVLILRSEKERHNERECEARTLNCKYCKVSFNFKEIKA------HDEICQKFPMQCK---DCGKKKIPREKFLDHSKSCAKSKTACPFSEVGCKVVVDVADAVTHNEGLVFIVF-SVVVLQVRALENIVCVLNREVERSSLTLEAFSRQHRLDQDKIENLSNKVRQLERTLTMRDLQLAETDQTLRELQFCTFDGVFVWKIADFSRRRQDAVAGRTPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRGKCDALLKWPFSQKVTLMLLDQN-NREHIIDAFRPDVTSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDLTGL 470          

Query:  145 SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQ----IDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNM-VEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEE--YVSHTSNLIS--------------------------------------------------KIKDMENTIKNLTDELEN-----QKVLTKELLDMNKKSSLS--VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            S+  + +C  C+ +L+   Q  CG + C  C K   ++GP PC + +     + E+ ML + E    DNA  +EI  L  KCP   CS    L+   V+H   CEF  + C  CQ  +   DK+ H++ +CE R L C+YC    SF+D+K+       ++ C K+   C  +C      +    EH K C+K K  C F  + C   +   +N  +H +E+   + H   +++                                                  K+  +EN +  L  E+E      + +  ++ LD  K  +LS  V + + T+  ++        QA+        +  F+WK +DF  +R DA +GR  ++ S  FY+S++GYKMCLR+Y  GDG G+G+HLS+FF +M+G++D LL WPF QKVTL ++DQ    +H  D F+PD  S  +Q+P+ E NIASG P F  L+ +   S Y ++DTI++K  VD  G+
Sbjct:   35 SMEPKYQCQQCKGVLRKPFQAQCGHRFCVFCFKQLTSSGPIPCEACRAEGIFEMEHSMLSITEAF-PDNAARREIDGLPAKCPNDGCSWNGTLKEYEVQHEGRCEFERVKCEACQMMILLSDKDRHNERECEARTLNCKYCKVTFSFKDIKA------HDEICQKFPMQC-KDCGKKKIPREKFAEHSKSCAKSKSACQFSEIGC---RAVVDNGKQHEHEQSSIIEHLRLMLAVLSTVRVRSDGPGEWQEDSGLGLYRGPEDAAPPGAHAAAHNAAGGPGVQQKMTALENIVCVLNREVERTVLRLEALTRQQQLDQEKIENLSNKVRQLERTL-TMRDLQLAESEQALRELQFCTYDGVFVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQN-NREHIIDAFRPDISSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDLTGL 531          

Query:   85 MSQSLSQIPTILELYEFNFPS------LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNM-VEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLK---EHLKLCSKKKLECPFHSLNCN--VDKMTKENLMKHLNEEYVSHTSNLIS---------------KIKDMENTIKNLTDELENQKVLT-----KELLDMNKKSSLS--VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            M+      P+ LE  +  FP       L D+  C +CQ+IL+   Q  CG +                 P+                  DNA  +E+ +L+  C  + CS    ++     H   C+F  I C  C+  L+A + E H++ +C  R L C+YC E   F+++K+       ++ C KY  IC   C    K+  +   +H+KLC+K +  C FH + C+  V K     ++   +  Y S T  L                 K+   EN +  L  E+E           +  LD +K   L+  V + + T+  L+  S       +   S    +  F+WK +DF  KR DA +GR  ++ S  FYTS++GYKMCLRIY  GDG G+GTHLS+FF +M+G  D LL WPF QKVTL ++DQ    +H  D F+PD  S+ +Q+PV + NIASG P F  LS + + + Y ++DTI++K  VD  G+
Sbjct:    1 MAAQEPSPPSSLEGNKPGFPRKILANKLEDKHLCNICQKILRRPFQAQCGHRFS---------------PASAF--------------PDNAAKREVEALEAVCINEGCSWTGTIKEYEATHEGQCDFMIIPCPSCKELLRANELERHNERECPERTLNCKYCKEPFHFKNIKA------HDEICPKYPMIC-EGC-AKKKIPREKYVDHIKLCTKFRTPCRFHVVGCDMSVSKPQWNLILTPRDLLYTSFTVPLSQTKVAELSRRCQELELKVGTFENIVCVLNREMERSATTMEAYNRQHRLDQDKIEILNNKVRQLERTV-GLRDLSIVEMEGKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQN-NREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDDTIFIKAIVDLTGL 459          

Query:  166 CVLCQRILKNAKQTSCGCKACENCIKSYLANGP-------KPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCN-KCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNS-----------DREDFCVKYTAIC-----PNNCDVHTKVCLKEHLKLC--------------SKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVS------------HTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETI----------EKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMN-NSLYCKNDTIYLKIAVD 1464
            C  C  +L  A QT CG + C  C+   L N         K  P  + D  ++ML +D    +DNA NKEI  L+V C  + C     L++  +H + CE+  I CN  C   +  K   +H +  C   K  C+ C   ++  +L+S+   S            R++ CV     C     P+    H       HL L                ++ ++ P   L  N  ++  ++     N++ +S                L  +++ MEN I  L  E+E  + LT  +L+ +  +++++++  E +          + L+  S    I A ++ S    + TF+W+  D   K  +A +G+K S  S  FYTS +G+K+C+R+Y  GDGVGKGTH+S+FF IMKG++D LLSWPFKQKVT  ++DQ    +H  D F+PD RSA +Q+PV E N+ASG P F  LS + +    Y K+DT+++K  VD
Sbjct:   29 CSSCNNVLNEAHQTQCGHRYCRACVMWLLRNNKDLICTKCKEDPGSESD-SSMMLTLDH-FFSDNAINKEIQELRVHCVNQGCGWRSTLKDFEDHQSQCEYALIPCNIGCGLMVLRKTLATHLEKGCPNNKTTCQVCCSALTPAELQSVTYFSLFLKDSKQESPKRKETCVFSEIGCTFKGNPDKVREHEVSSTSAHLHLLVEVVRNVQMSVPPPPERTVQYPALDLTLNGGELETDSGDTGANDKALSLHDDQAELEVGQQLHALQQRLQIMENIITALNREVEKTQ-LTVVVLERDNHNNMNLIQHLEAVVAEQQQRLIRKDLQISSLQQSISAQQDVSY---DGTFLWRICDVSQKLKEAATGQKSSQYSPAFYTSRYGFKVCMRLYMYGDGVGKGTHISLFFVIMKGDYDPLLSWPFKQKVTFFLIDQNQ-REHVVDAFRPDLRSASFQRPVSEMNVASGCPLFFPLSKLRSPKHAYVKDDTLFIKCVVD 515          

Query: 1021 NATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            N T IWK  D++ ++ +A + + +S+ S PFYT  FGYKMC R+Y  GDG+GKGTHLS+FF +M+GE+D LL WPFKQKVTL +MDQ    KH  D FKPD  S+ +++P  E NIASG P F+  + ++ N  Y K+DTI++K+ VDT  +  P
Sbjct:    3 NGTLIWKIRDYKRRKAEAVASKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPARKHLGDAFKPDPNSSSFRRPTGEMNIASGCPLFVAQT-VLENGTYIKDDTIFIKVTVDTSDLPDP 156          

Query:  148 LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKP-CPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCP-FKLCSSEMPLRNMVEHINSCEFREISC--NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHT--KVCLKEHLKLCSKKKLECPFHSLNCNVD------KMTKENLMKH------------------LNEEYVSH----------TSNLISKIKDMENTIKNLTDELENQKVLT----KELLDMNK--------------KSSLSVLK-----TQETIEKL---------KTKSFPTPIQAVENKSVIFR-------NATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIM--NNSLYCKNDTIYLKIAVDTLGI 1476
            L D+  C  C  ++ N  QT CG   C  CI+  L N     CP   I      L   E++  DN   +E+ +L+V C     CS  +PL N+ +H+ SC++  + C  + C   L  K+   H ++ C  R   C YC +      L      S     C +    CPN C +H   +  LK+H   C +++ +C +    C V       K+ ++    H                  L +++ +            SNL  ++   + T+  +   +E Q+ L     +EL D+                ++SL  L+     TQ   E L          T+     +Q ++     F+       +   IWK  D+  K+   E+G   ++ S PFYTS  GYK+  R+Y  G+G  +GTHLS++  +M+G+FD LL WPF+Q VTL+++DQ     H S +F PD  S  +++P  E N A G P+FI  + +    N+ Y ++DT+++K+ VDT G+
Sbjct:   41 LDDQFVCPACGGVVFNPHQTGCGHIFCSPCIRVILENNETSKCPFDGI------LIKPEEVFQDNCCKRELLNLEVFCTNSPACSQTIPLCNLQDHLKSCQYEALQCPNSSCTDILLRKNLPDHQRSHCSYRTELCRYCQKPYPVSQLTDHEKTS-----CPEAEVQCPNKC-IHLVKRHKLKDHADECPEQETDCIYKKYGCTVRNKRGQVKVHEQTEFNHHVLLLLESNSKLIKQVDQLQQDFAAQQGELKERNLLVSNLKREVSKCDTTVSAMQRSVEEQRELVSSVKRELKDLRDVLEADLTKEELVSLRASLDSLREQVAMTQSLREHLGALGQTCQSHTRLLDIHVQQLQCSEQRFQQLESTSYDGKLIWKVHDYHRKK---EAG--TALNSPPFYTSHSGYKLSARVYLGGEGTARGTHLSLYVMLMRGDFDSLLPWPFRQNVTLAVLDQSGNRNHVSLSFTPDLASNNFRRPTSETNAALGFPRFITHADLEAPRNAAYVRDDTLFIKVKVDTTGL 547          

Query:  367 KVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSF-RDLKSIHLNSDREDFCVKYTAIC-------------PNNCDVHTKVCLKEHLKLC----SKKKLECPFHSLNCNVDKMT--KENLMKHLN--EEYVSHTSNLI-SKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSF------PTP------------------IQAVENKSVIFRNATF----IWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            +V C F  C + +    +  H  SC  R   C  C + +     E H K +C    L C    EE    R   S H+++     C   T +C               +   H +  ++ H  L     S+ +L+C    L C+++  T   E L + +   E+ +SH S L  S    + +T++ LT   E  + L        + +  + L+      + + ++       P P                  +   E +  +   A +    +WK  D+  ++ +A SGR +S+ S PFYTS FGYKMC R Y  GDGVG+GTHLS+FF +M+GE+D LL WPF+++VTLS++DQ A  +H SDTF PD  S  +++P  + N+ASG P F+   + +  S Y  +DT+++++ VD  G S P
Sbjct:    5 RVLCDFPRCGTSVQRTRLAAHRASCPHRAEFCKYCSAAVTCSLLERHHKEECAQYPLPCPNNCEEHGIPRAELSQHMSA-----CAMSTKLCGFHMLGCTFKQGTSESVREHEESAVRSHFTLVISRNSELELQCA--RLQCSIEDHTNMSEMLTQRVAQLEQDLSHWSTLTGSNNTRLGSTLEMLTQHNEQLQSLHVAQRAPQRDADTAALRRDMATLRERLRALEAALGNPGPCEERCHMHEQRLTMHDGLLDTAERRLQVLETAGYSGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPDPASGSFRRPDGDMNVASGCPLFV-SHVALEGSSYLVDDTVFVRVVVDPGGASDP 420          

Query:  439 CEFREISCN--KCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHT--KVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKEL 897
            C    + C+  +C + +Q     +H +  C  R   C+YC   ++   L+  H     ++ C +Y   CPNNC+ H   +  L +H+  C+     C FH L C   + T E++ +H      SH + +IS+  ++E     L   +E+   +++ L
Sbjct:    1 CPHERVLCDFPRCGTSVQRTRLAAH-RASCPHRAEFCKYCSAAVTCSLLERHH-----KEECAQYPLPCPNNCEEHGIPRAELSQHMSACAMSTKLCGFHMLGCTFKQGTSESVREHEESAVRSHFTLVISRNSELELQCARLQCSIEDHTNMSEML 151          

Query:  916 SSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            S+LS   TQ      +        Q +E  S    N   +WK  D+  ++ DA SGR +S+ S PFYTS FGY+MC R Y  GDGVG+GTHLS+FF +M+GE+D LL WPF+Q+VTL+++DQ A  +  SDTFKPD  S+ +++P  + NIASG P F+   + + ++ Y ++DTI++K+ VDT  +  P
Sbjct:  292 SALSRHDTQLFAHDTRLAEMDLRFQVLETASY---NGKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPDPASSSFRRPTSDMNIASGCPLFV-SHVALESASYLQDDTIFIKVVVDTGELGDP 477          

Query:  370 VKCPFKLCSSEMPLRNMVEHIN-SCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHT--KVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQ-----------KVLTKELLDMNKKSS 921
            V CP   C+  +    +V H+   C FR  SC  C  ++   +K  H + +C                                 +Y   CPN C+  +  +  L  HL +C  K+ EC F    C   K T + L +H +     H S + ++  ++E  +  L  +L  +           + L KEL+ + + +S
Sbjct:   47 VNCPHAGCTERLLRGELVNHVALGCHFRTESCRYCNQQVPLAEKRKHYETRCP--------------------------------RYPIPCPNKCEEQSIAREELVSHLGICPYKQAECFFSQFGCKY-KGTLQGLKEHESGATQQHLSLVTARSANLELKVSMLQSQLAERANSADLLGTRVRELEKELISVGQTAS 211          

Query:  127 YEFNF-PSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLA---NGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQ---------------------------SKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH-TKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIK--------------------NLTDELENQKVLTKEL-----LDMNKKSSLSV-LKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKF------------TDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRI-------YPAGDG------VGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQ-EAGTKHHSDTFKPDARSACYQKPVDECNIAS-GSPKFILLSLIMNNSLYCKNDTIYLKIAVDT 1467
            YE +F P L  + +C +C   L+   QT CG + C  CI   +     GPK CP      +N +LH +  +  DN   +EI SL V+CP K C     LR + EH   CE+ ++ C +C+                            K+  KD ++H++  C +  + C++C +E+  R+    HL  D +   V  T   P  C+    +  L  H+   ++  +      L  N  K+ +  + +       + +S   + +  + +T                      +   EL+  + +T+ L     L +++   LS     Q+ +    T+   +    V           F W+             + F S  +  ++     + S  FYT   GY++CLR+        PAG         G+  HL++F  +++G++D  L WPFK ++ +S++DQ E  + H ++    D + + +Q+P    N    G   F+ ++ + + S Y ++D + ++  V T
Sbjct:   51 YEADFEPPLESKYECPICLMALREPVQTPCGHRFCRACILHSMRLRDAGPK-CP-----VDNAVLH-EGQLFPDNFAKREILSLTVRCPNKPCGHRGELRALQEHQLRCEYAQVPCVRCEMPVCRRDLAKHEEQECMRRIVTCLHCCEKMAYKDSKNHEQ-MCPLVVVNCKHCQQEL-IREQLGPHLEVDCQQAQVPCT-FSPLGCEAQMVRSLLAAHMHEHTQVHMR-----LLANGLKILRIQVGQGAQPSSAAGSSAPPNSLSWLSSTSGGDVQTAGASRSQGSRDRAACDCAQELDRLREITRTLEERVVLQLHQIRELSAKTDNQQGLLAEATRLVRSLEARVAESESRLCAGIFTWRVERFSRLLPGGLASGFASDGMHPDA--PAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAGRQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCERDSVHVTEMMDADPQLSAFQRPSVHRNPKGFGYMNFMDINTLHHRS-YLRDDCLVVRCEVVT 564          

Query:  157 RLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNM-VEHINSCEFREISCNKCQSKLQAKDKE--SHDKNKCEMRKLKCEYCLEEMSFRDLK--SIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKI-KDMENTIKNLTDELEN---QKVLTKE--LLDMNKKSSLSVLKT------------QETIEKLKTKSFPTPIQAVEN------KSVI------------FRNATFIWKFTDFESKRIDAESG--RKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQK 1257
            R  C  CQ +L++A QT CG + C+ CI   + +  + C    ++  N +++       D A  +E+  L V+C  + C     L    V H+  C++  + C      L     E   H   +C +R + C  C + + +R L+   +H  S R   C     +C        K    E  + C K +  CP+  L C + +   E+L  H       H + +     K  E  IK   D +++    +++  E  L  M+++      +             Q  I++ +T      +  VE+      +S++              N  F+WK     ++  +A +G  R   + S  F+T+ +GY++ LR+  +G+      H+S +  +  G +D  L+WP++ K
Sbjct:    2 RFACGSCQGLLRDAVQTHCGHRFCKPCIARLITSVHRSCNDTLMN-SNFLVYSPTQFFPDAALRREMGVLPVRCVSEGCEWRGRLLEYDVAHVERCDWVLVPCLLAGCALLLPRAELHRHVAQECSVRPVPCAACAQLLPYRQLQKHQLHCRSRRTREC----KLCGQKSIPEDKWQHHEE-RRCMKNRDTCPYSPLGC-LYRGHGESLHNHDKNSVEVHLAIVYDAFKKTFEQLIKGHADNIKHPPSARLVAAEAQLATMDRRVEEVAKRVERDVRVSEASTRQGNIDRDETARLQNKMARVEHSDQETERSILGLTRRLAELENTAYNGMFLWKIKHVINRLREAGNGAERPPQIDSPAFFTTRYGYRLRLRLCRSGE------HVSAYAMLGPGPYDATLAWPYQLK 398          

Query:  166 CVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKC---PFKLCSSEMPLRNMVEHINSCEFREISC--NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPN------NCDVH----TKVCLKEHLKLCSK------------KKLECPFHSLNCNVDKMTK--ENLMKHLNEEYVSHTSNLISKIKDME-------NTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATF----IWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVD 1464
            C  C+ I+K+A QT+CG + C  CI   L+ GP  C      C + +     +   D   ++EI  L V C   P   C  E  LR+   H   CEF  ISC   +C  KL       H +N+C+ R+  C YC + +    +K  H     E  C  Y   CP         +VH    T+    E  + C              KKLE     +  N  +  +  EN+      + +   +N+ +K  D E       + +  L  E+    V  +E  D+ ++     L+ Q  +    T      I  +E +    +  TF    +WK T+  +KR +A SGR  S  S  F+T   GYKMC RIY  GDG+G+  H+S+FF IM+GEFD LL WPF+QKVTL ++DQ+   +H  D F+PD  S+ +Q+P  E NIASG P F     +  ++ Y ++DT++LKI VD
Sbjct:   24 CAKCRLIVKDAVQTACGHRYCSPCISPLLSRGPIQCDV----CGSTI--TKPETFRDKFADREILELHVHCVNQPHG-CPWEGELRHRQNHHTKCEFNPISCVHPECGKKLSVAKLPEHLQNECQYREETCSYCEQPVVVARMKEHH-----EKTCPSYPVNCPKCSKELIRVEVHSTPFTREPRLEKGRGCENTLEVLEDHESRIKKLEQRGGGIGVNGLQSMRISENIDNEAIGDVLRRVANVEAKGADHEVLVVEAHSAVDELRREVGRLNVKLQESDDIIRR-----LERQLELHDQGTGLRNLAIADLEERLNTLQGTTFDSVLLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQD-NVEHVIDAFRPDPSSSSFQRPRAEMNIASGCPLFCSHEQLTQHA-YIRDDTMFLKIIVD 477          

Query:  148 LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCP-----------------------------SKQIDCENVM-LHMDEDINA---------------DNATNKEIASLKVKCPFK-----LCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKE-SHDKNKCEMRKLKCEYCLE-----------EMSFRDLKSIHLN----------SDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKT----QETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            L  + +C +C   LK+  QT CG + CE C++  L  GP  CP                             ++Q+ CE +  L   E+  A               +    +++ +   +C FK      C   +P  +M +H+ +CE   + C  C ++   +D+   H  N CE  +L C +              E  FRD  S+H+N            R +   K + +         ++  +      + + L      LN  +++   E   +    +       + + I++ +  +  + +E       +     M    +L   +     Q  +  ++       +Q +E  S    + T+IWK  ++  +  +  SG+  S+ S PFY   +GYK C R+YP GDG+GKG+HLS+FF +M+GEFD LL WPF+QKVT  ++DQ+       DTF+PD  S+ +++P    NIASG P FI  + +   + Y ++DT+++KIAVDT G+
Sbjct:   15 LDPKYRCPVCGNALKHPVQTPCGHRFCEGCLEPIL-RGPSKCPVDGEELKIDGVFKDVCCRREILCLACYCPNRQLGCEWMKDLQYLEEHRANCEYKGVQCHNPGCQEKVAKRDLEAHLERCEFKPSDCQYCLQRIPAASMEDHLQTCEKHPVVCPHCGAEGICRDELLHHQTNICEQAELPCSFAKHGCHFKGTREALETHFRDQASVHVNLLLTATQNEEKARSEMAAKLSQMEKERAKQQEQMYEQREALAVANQNLRTYQGKLNV-IERSVAEQRRELAELKERIQLQEVEAAIREQDRRLGMIENEASRGAAPSSGPGSMGGTMALERRQDRNEHQLALHDIQLAEHDLKLQMLEATSY---DGTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQDR-VHDIGDTFRPDPTSSSFKRPTSNMNIASGCPLFISHTNLQTRA-YVRDDTMFIKIAVDTTGL 526          

Query:  133 FNFPSLSDRLK-CVLCQRILKNAKQT-SCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDI-NADNATNKEIASLKVKCPFK--LCSSEMPLRNMVEHINSCEFREISC-NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVC---LKEHL-KLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGT---KHHSDTFKPDA---RSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            F  P   +R   C +C+ I  +  Q   CG + C++C K+   +    CP    D       +D+ I + D A   ++  L  +C      C  E+P   M+ H   CE+ +I C N C +K Q + K+ H    C  + + C YC ++   R+ K  HL       C+     CPN CD    +    L EH+ K C + KL C F SL C   + ++E + KH+  E + H   +   + + +  + N   + E  + + K++      S +  L      EK+                    ++  IW+  D+  K  +A++G   ++ S  F TS+ GY++C  +   GDG GKGTH+SVF +++KG FD LL WPF  +VT  +++Q       KH   + KP+          +P  E N + G  KFI    I + + + K+DT++LK++VD  G+S+P
Sbjct:   43 FKKPPFEERKHLCPVCEDIFVSPVQIKECGHRLCQHCYKTIWRSPEPKCPKCSGD-------LDDKIPDVDQAFENDMNELPCRCINHEWGCKVEVPFTQMITHKGECEYSDILCDNDCGAKFQRRFKQKHLDKDCPKKIISCPYC-DDRHLRENKKEHLED-----CLLIPLPCPNKCDKTLTIPRGQLDEHIEKECPRAKLMCEFESLGCQ-HRCSREKMAKHMKSEIIGHVKMIFGVVLEQKEKLDNHAQKFEEHETIMKQV-----DSRVGDL------EKIA-------------------HSQIIWRIEDYTRKLKEAKAGNAETLFSPTFTTSKHGYRLCASVCLNGDGKGKGTHMSVFVSVLKGAFDALLKWPFHYRVTFFLLNQHENPEERKHVKFSIKPNPIPDNEPFLGRPRLEKNASFGGAKFIKHEEIESGN-FIKDDTVFLKVSVDCDGLSEP 464          

Query:  127 YEFNFPSLSDR-LKCVLCQRILKNAKQ-TSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKL--CSSEMPLRNMVEHI-NSCEFREISCNK-CQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVH--TKVCLKEHL-KLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKV-SVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSD---TFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAV 1461
            YE  F    D+  +C +C   L++  Q T CG + C+ CIK  + N    CP      +N+ L++ + I  DNA +++I S+ + CP     C  +  + ++ +H+   C   E+ C K C + ++    E H   +C  R + C +C +E+ F D+ ++HL S     C  +   CP  C     TK  L  HL + C    + C F    C   K  ++ +  H+ E   SH + L            +L  E + Q    KE L + K          E I+          +Q VE +S    N  FIWK   F  K +DA++GR    + S+ FYTS  GYKMC  ++  G G G+G ++SV   +  GEFD +L WP   + T +++DQ   TK   D   TF+P + S    +P  +  +  G+ +F+L   +   + YCK++TI++K +V
Sbjct:    4 YEVRFVVPLDKSFECPVCLMALRDPVQVTPCGHRVCQTCIKPIIRNRRPRCPL-----DNLTLNVGK-IFPDNACHRQILSMDILCPHHGDGCEWQGTISDLEKHLERGCNLSEVRCPKDCGASVERGKLEGH-YPECSRRLVNCTHCNKEVVFADM-NVHLQS-----CASFPISCPLTCGAKDLTKEALAVHLNQECPLLVIPCRFAEAGCTF-KAKRQKMAAHVQESLTSHVAMLC-----------DLVCEQKLQISAQKERLLLQK----------EHIQ----------LQIVECRSRC-ANGEFIWKIQCFSRKLMDAKTGRASEPMISEAFYTSPHGYKMCAGVWLNGIGTGRGRYISVGLQVQSGEFDSILKWPLYPRYTFTLLDQSEDTKTKRDVVATFEPQSIS----RPSADRQLGKGARRFVLQDEVCGTT-YCKDNTIFIKFSV 410          

Query:  133 FNFPSLSDRLKCVLCQRILKNAKQTS-CGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPF--KLCSSEMPLRNMVEHINSCEFREISC-NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKV----------CL------------------KEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLIS---------KIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEA---GTKHHSDTFKPDARSACYQKPV-DECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVD 1464
            F  P++ + L C +C   ++NA Q S CG + C++C+   L      CP      +N  +   + + AD+ TN+ I SL V C +    C  +  LR +  H+  C+F    C N C +++Q +    H    C  R++ C  C  EMS+  L+ + L    E   V     CP NC    +V          CL                  + H + C    L CP    NC V ++ +  +  HL+ +     SN++          K     +  +++ + ++    L  EL           ++ Q+ I  LK          +      + ++  +W+  DF     + +      + S  FYTS +GYK  + ++P G+G G+GTHLS++  ++ GE+D LL WPF+ ++TL+++DQ       +H S +F PD     +Q+P  +  ++  G P+F+     + +  Y ++D ++LK+ +D
Sbjct:    7 FFVPAVRENLLCRICHLPVRNAVQVSVCGHRFCDSCLNHALGETRLRCP-----VDNTAIDYSQ-VYADDVTNQMIMSLTVICDYYQAGCKWKGQLRKLQGHLAECKFVSADCSNSCGARIQKRRMSEHTSKDCPKRRVCCARCKAEMSYEQLR-VSLRYRNEGALVSDHVTCPRNCGERMRVQDKARHMREDCLNRWVFCQYCNTEIVFRDRQTHHQSCPSFPLSCPN---NCGVAQIPRGEVELHLSRDC---RSNIMQCPFRHVGCHKQFPQRSLQRHIEESVQQHLELVSEL----------AIQQQKEINSLK---------EIVRHCKPYHDSKLLWRIDDFWEAFDEGKRKPGTELHSPVFYTSNYGYKFKVVLFPYGNGSGEGTHLSLYIRLLPGEYDSLLPWPFEGQITLTLLDQSTDKRAKRHISQSFSPDPNWKSFQRPSKNSTSLGFGYPQFV-SHRGLESIGYVRDDVLFLKVTID 462          

Query:   94 SLSQIPTILELYEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPS---KQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNM-VEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKE----HLKLCSKKKLECPFHSLNCN--------------------------VDKMTKENLMKHLNEEYVSHTS--------------------NLISKIKDMENTIKNLTDELENQKVLTKEL-----LDMNKKSSLS-VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            SLS +P I  L   + P + D+ KC  C ++L+   Q  CG + C +C +   ++GPKPC +   ++I  E + +    +   DNA  +EIASL  +C  + C     ++    +H   CEF +I C  CQ+ +  KDK+ H+  +CE R L C+YC    +F+D+K+       ++ C K+   C    D   K   +E    H K C+K K  CPF  + C                           V  MT+  L    + E+   +                     +L  K+  +EN +  L  E+E   +  +       LD  K  +LS  ++  E    +K        Q V        +  F+WK TDF  +R +A SGR  ++ S  FY+S++GYKMCLR+Y  GDG G+GTHLS+FF +M+ ++D LL WPF QKVTL ++DQ    +H  D F+PD  S  +Q+PV E NIASG P F  L+ +   S Y ++DTI++K  VD  G+
Sbjct:   15 SLSSLPGI-PLSVLSVP-MEDKYKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSGPKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKDIKA------HDEICQKFPLQCK---DCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNREVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQN-NREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVDLSGL 523          

Query:   94 SLSQIPTILELYEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPS---KQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNM-VEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKE----HLKLCSKKKLECPFHSLNCN--------------------------VDKMTKENLMKHLNEEYVSHTS--------------------NLISKIKDMENTIKNLTDELENQKVLTKEL-----LDMNKKSSLS-VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            SLS +P I  L   + P + D+ KC  C ++L+   Q  CG + C +C +   ++GPKPC +   ++I  E + +    +   DNA  +EIASL  +C  + C     ++    +H   CEF +I C  CQ+ +  KDK+ H+  +CE R L C+YC    +F+D+K+       ++ C K+   C    D   K   +E    H K C+K K  CPF  + C                           V  MT+  L    + E+   +                     +L  K+  +EN +  L  E+E   +  +       LD  K  +LS  ++  E    +K        Q V        +  F+WK TDF  +R +A SGR  ++ S  FY+S++GYKMCLR+Y  GDG G+GTHLS+FF +M+ ++D LL WPF QKVTL ++DQ    +H  D F+PD  S  +Q+PV E NIASG P F  L+ +   S Y ++DTI++K  VD  G+
Sbjct:    8 SLSSLPGI-PLSVLSVP-MEDKYKCQQCLQVLRKPVQAQCGHRFCVHCFRQLTSSGPKPCQACRKEEIYEEPMSILNSSEAFPDNAAGREIASLPARCLNQGCDWTGSIKEYEAKHEGRCEFEQIQCEACQALVLRKDKDRHNDRECEERTLNCKYCKVTFNFKDIKA------HDEICQKFPLQCK---DCGKKKIPREKFNDHAKSCAKSKSACPFSEVGCKSVVENGKISEHEHSSTMEHLRLLLPMVLSMTRTRLDTSPSGEWQEDSGLGLYRAPDDGCGAAASVPSVDLDKKVSALENIVCVLNREVERSSLTLEAFSHQHRLDQEKIENLSNKIRQLERSLTVKDLQLSEAEQMVRELQYCTYDGIFVWKITDFSHRRQEAVSGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGTHLSLFFVVMRSKYDALLKWPFSQKVTLMLLDQN-NREHIIDAFRPDITSTSFQRPVSEMNIASGCPLFCPLAKLAGKSPYLRDDTIFIKAIVDLSGL 516          

Query:  166 CVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKL--CSSEMPLRNMVEHINSCEFREISC--NKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            C  C+ +L   +QT CG + C +CI   L+     CP+   D E +     + I  D   ++EI +LKV C  +   C  +M L+ + +H+N C F E+ C   KC+ ++  K+   H   KC+ R+  CE+C  +M   +L+       +E  C  +   CPN+C   T   L    KL S        H+      ++   +L + L +E  S    L        +T++     LE     + E   +N+   +       ++ +++        Q +E  S    N T IWK  D++ ++ DA +G+ +S+ S PFYT  FGYKMC R+Y  GDG+GKGTHLS+FF +M+GE+D LL WPFKQKVTL +MDQ    KH  D FKPD  S+ +++PV E NIASG P F+  S ++ +  Y K+DTI++K+ VDT  + +P
Sbjct:   48 CEACRLVLCQPRQTECGHRFCYSCINDILSCPNPVCPA---DMEPLF---KDKIFRDVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVCPFFEVPCPLGKCKERMMRKEIPEHLAWKCKYRESTCEFCKNKMPLTELQK-----HKETVCPAFPVSCPNHC---TSSSLPRSEKLMSS-------HTEKLLELELELRSL-RQLRDEMESLRGTL--------DTVRTRLSALEQGGRASLET-QLNRHDDML------SVHEIRLADMDLRFQVLETASY---NGTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFKPDPSSSSFRRPVAEMNIASGCPLFVSQS-VLESGTYIKDDTIFIKVTVDTSDLPEP 450          

Query:  820 KIKDMENTIKNLTDELEN-----QKVLTKELLDMNKKSSLS--VLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            K+   EN +  L  ELE      +    +  LD +K   LS  V + + T+  L+  S       +++ S    +  FIWK +DF  KR DA +GR  ++ S  FYTS++GYKMCLRIY  GDG G+GTHLS+FF +M+G  D LL WPF QKVTL ++DQ    +H  D F+PD  S+ +Q+PV + NIASG P F  LS + + + Y +++TI++K  VD  G+
Sbjct:  346 KVSTFENIVCILNRELERSCATMEAYNRQHRLDQDKIEILSNKVRQLERTV-SLRDLSIVEMEGKMKDMSAATYDGIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQN-NREHIIDAFRPDISSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDETIFIKAIVDLSGL 569          

Query:  109 PTILELYEFNFPS------LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPS---KQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNM-VEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLK---------EHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTD---ELENQKV--LTKELLDMNKKSS 921
            P+ LE  +  FP       L D+  C  C++IL+   Q  CG + C  C    +++GP+ C +   + +  E   +        DNA  +E+ +L   CP + C+    ++     H  SC+F  I C  C+  ++A ++E H++ +C  R L C+YC E    +++K+       ++ C KY  +C          C K         +H+K CSK K  C FH + C+   + KE +  H  +    H + L+  I  ++ ++++L     E+ +QK+  L + L D+  + S
Sbjct:   10 PSSLEGSKPGFPRKILANCLEDKHLCNSCEKILRRPLQAQCGHRFCCFCFNRTVSSGPQKCSACIKEDLFEEPTSILKQGGAFHDNAARREVEALAAVCPNEGCTWTGTVKEYEASHEGSCDFTIIMCPSCKELMRANEQERHNERECPERTLNCKYCKEPFLLKNIKA------HDEICPKYPMMCEG--------CAKKKIPREKYVDHIKFCSKFKAPCRFHVVGCDTS-VEKEKIHDHERQCSYEHLNLLLHFIMGIKVSLESLQPQRLEVASQKLHELHQSLRDLELRMS 289          

Query: 1021 NATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGI 1476
            +  FIW+ +DF  KR DA +GR  ++ S  FYTS++GYKMCLRIY  GDG G+GTHLS+FF +M+G  D LL WPF QKVTL ++DQ +  +H  D F+PD  S+ +Q+PV E NIASG P F  LS +   + Y ++DTI++K  VD  G+
Sbjct:  446 DGVFIWRISDFAKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGLSDALLKWPFNQKVTLMLLDQ-SNREHIIDAFRPDVTSSSFQRPVSEMNIASGCPLFCPLSKLDAKNSYIRDDTIFIKAIVDLTGL 596          

Query:  109 PTILELYEFNFPS------LSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPS---KQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNM-VEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLK---EHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQ 990
            P+ +E  +  FP       L D+  C  C  IL+   Q  CG + C  C    ++NGP+ C +   ++I  E   +        DNA  +E+  L   C  + C  +  ++   ++H   CEF  I C  C+ +++  ++E H + +C  R L C+YC E   F+++K+       ++ C KY  IC   C    K+  +   +H+K CSK +  C FH + C++  + KE +  H       H + L+  I  M+ +++ L  + +  +    +L+++ K    S+   +  + +L T S   P+Q
Sbjct:    9 PSSMESNKPGFPKKILGNKLEDKHLCNCCHNILRRPIQAQCGHRFCSYCFNRTVSNGPQKCNACIKEEIFEEPTSILKQGCAFPDNAVRREVEGLSADCINENCPWKGTIKEYELDHEGKCEFMIIPCPSCKERIRFSEQERHSERECPERTLNCKYCKEPFHFKNIKA------HDEICPKYPMIC-EGC-AKKKIPREKYVDHIKFCSKFRTPCRFHVVGCDMS-VEKEKIHDHERAFAYEHLNLLLHYIMGMKVSMEGL--QPQGLETAGHKLVELQK----SLRDLEARVSQLSTTSSGPPVQ 300          

Query:   85 MSQSLSQIPTILELYEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            MSQSLSQIPTILELYEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP
Sbjct:    1 MSQSLSQIPTILELYEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 467          

Query:   97 LSQIPTILEL---YEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKT-KSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            +++I + +EL   Y  + P+LS  LKC++C  +LKNAKQT CGCK CENCI  YL+ GPK CP+K+  C N +L +D+DI  DNATNKEI +LK+ CPFK C+    +  + +H+ SCE+R+++C+ CQ ++ AK+K+ H   +CEMR  KCE+C + M+ + L  +HLN+ + + C +Y   CPNNC    ++ LK HL+ C           LN   D     N   H+ E   +  SNL+ +I  +  T K+L  +LENQ V+ +E+       +   +K  + I  L+  +S P  I A  N    FRN +FIWK  D +S+  +AE   ++S+TSDPFYTSEFGYK+CLR+YP+GDG+GKGTHLSVFFA+MKGE+DDLL WPF+QK+TLS++DQE  TKH+SDTFKPD +S C+Q+P+ + NIASGSPKF  +S +  NS+Y KNDTIY+KI VD  GI +P
Sbjct:    1 MNKINSAVELLTNYSLDIPNLSSSLKCIICSSLLKNAKQTKCGCKVCENCINEYLSKGPKDCPNKE--CLNELLSIDKDIYNDNATNKEILNLKIACPFKGCAQLETVFKISQHVKSCEYRDVTCDPCQKRILAKEKQKHIDGECEMRITKCEFCHKTMTIKYLNEMHLNTTKNELCSEYVGHCPNNCGETKELNLKLHLETC-----------LNRKSDDQNDTNY--HIQEFSNTQLSNLLKQIALLNQTSKDLLTKLENQDVIIREMSTKYIALTEDNIKLTKKINALEAERSNPVKIIAKTND---FRNGSFIWKIKDLKSQIQNAERSERLSITSDPFYTSEFGYKLCLRVYPSGDGLGKGTHLSVFFALMKGEYDDLLPWPFRQKLTLSLLDQENFTKHYSDTFKPDPKSPCFQRPILDSNIASGSPKFYSISHLSFNSIYYKNDTIYIKITVDLSGIHRP 449          

Query:   97 LSQIPTILEL---YEFNFPSLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKT-KSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAVDTLGISKP 1485
            +++I + +EL   Y  + P+LS  LKC++C  +LKNAKQT CGCK CENCI  YL+ GPK CP+K+  C N +L +D+DI  DNATNKEI +LK+ CPFK C+    +  + +H+ SCE+R+++C+ CQ ++ AK+K+ H   +CEMR  KCE+C + M+ + L  +HLN+ + + C +Y   CPNNC    ++ LK HL+ C           LN   D     N   H+ E   +  SNL+ +I  +  T K+L  +LENQ V+ +E+       +   +K  + I  L+  +S P  I A  N    FRN +FIWK  D +S+  +AE   ++S+TSDPFYTS              DG+GKGTHLSVFFA+MKGE+DDLL WPF+QK+TLS++DQE  TKH+SDTFKPD +S C+Q+P+ + NIASGSPKF  +S +  NS+Y KNDTIY+KI VD  GI +P
Sbjct:    1 MNKINSAVELLTNYSLDIPNLSSSLKCIICSSLLKNAKQTKCGCKVCENCINEYLSKGPKDCPNKE--CLNELLSIDKDIYNDNATNKEILNLKIACPFKGCAQLETVFKISQHVKSCEYRDVTCDPCQKRILAKEKQKHIDGECEMRITKCEFCHKTMTIKYLNEMHLNTTKNELCSEYVGHCPNNCGETKELNLKLHLETC-----------LNRKSDDQNDTNY--HIQEFSNTQLSNLLKQIALLNQTSKDLLTKLENQDVIIREMSTKYIALTEDNIKLTKKINALEAERSNPVKIIAKTND---FRNGSFIWKIKDLKSQIQNAERSERLSITSDPFYTS--------------DGLGKGTHLSVFFALMKGEYDDLLPWPFRQKLTLSLLDQENFTKHYSDTFKPDPKSPCFQRPILDSNIASGSPKFYSISHLSFNSIYYKNDTIYIKITVDLSGIHRP 435          

Query:   85 MSQSLSQIPTILELY-EFNFP-SLSDRLKCVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNL-TDELENQKVLTKELLDMNKKSSLSVLKTQETIEKLKTKSFPTP------------IQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAV 1461
            MS   + +P  ++ Y +  FP +L+D LKCV+C  +L NA QT CGC+ C+ CI+ +L N  + C +K   C  ++  M      DNA NKEI  L VKC +  C+ E  L+++ +H+NSCE+  + C KC+ ++  K   +H    C  R +KC  C   M +  L   HL+   ++ C K    CP  CD+   V L  H K C KK + CPF  L C+   +T + L  H+  E+ +H   L+ +   M+  I +L T  +E+ K +  EL +   + S  +    +      +    +             I    ++ + +RN  FIWK   F   + +AE G ++SVTS+PFYT EFGYKM ++IYPAGDGVGK THLSVFF +MKG+FDDLL WPFK KVTL+I+DQ+  T  +SDTFKPD RS CYQ+P +E NIASGSPKFI  S       Y KNDTI+LKI V
Sbjct:    1 MSSLSNNLPDNIKRYRKRRFPFNLTDNLKCVICSELLLNAMQTDCGCRYCQKCIEDHLVNS-RQCSTK--GCSTIISTM-----PDNAINKEIGKLMVKCLYDGCNHEEMLKDIGDHLNSCEYLTVVCEKCKLEMPGKMLPNHLLKDCVKRVVKCLNCESRMEYEILMKFHLDLYADNICPKLVDKCPYGCDIVGAVNLLAHRKECVKKPVRCPFVELGCS-KVLTNQQLSDHMKTEFPAHIRTLVEEFIKMKKEITSLETKLIESSKTIKLELSNFQNEISTKISNIDQMSNSSLSLQSSSSLTLQSSASSMANILKSNDEKINYRNGVFIWKVEHFPELKANAERGNRISVTSEPFYTKEFGYKMSMKIYPAGDGVGKSTHLSVFFTLMKGDFDDLLVWPFKNKVTLTILDQKNKTSDYSDTFKPDPRSTCYQQPTEEYNIASGSPKFI--SFTQLQEYYMKNDTIFLKIVV 463          

Query:  166 CVLCQRILKNAKQTSCGCKACENCIKSYLANGPKPCPSKQIDCENVMLHMDEDINADNATNKEIASLKVKCPFKLCSSEMPLRNMVEHINSCEFREISCNKCQSKLQAKDKESHDKNKCEMRKLKCEYCLEEMSFRDLKSIHLNSDREDFCVKYTAICPNNCDVHTKVCLKEHLKLCSKKKLECPFHSLNCNVDKMTKENLMKHLNEEYVSHTSNLISKIKDMENTIKNLTDELENQKVLTKELL--DMNKKSSLSVLKTQETIEKLKTKSFPTPIQAVENKSVIFRNATFIWKFTDFESKRIDAESGRKVSVTSDPFYTSEFGYKMCLRIYPAGDGVGKGTHLSVFFAIMKGEFDDLLSWPFKQKVTLSIMDQEAGTKHHSDTFKPDARSACYQKPVDECNIASGSPKFILLSLIMNNSLYCKNDTIYLKIAV 1461
            CV+C+ +L +  QTSCGC+ C +CI  +L+     C   + DC N +L ++ +I  D A ++ I +LKVKC  K C     L N+  H N C F  + C++C  K       +H K +CE RK  C++C        L  IH N    D CVKY ++CP  C +  ++ L EH K+C  K   CP+  + C+    T + L KH+    ++H S LI ++  ME+ +  L  +   +    K+L+  D +K  S  + + Q  + + K +S    +        +F+N  +IW   +F   + +A++ R  S+ SDPFYT EFGYK+C++IYP GDG+GK THLSVFF IM+GE+D +L WPF+ KVTLSI+DQ +   H+S+TF PD +  C+ KP  + N+ASGSPKFI  S + N   Y  N+  +LKI+V
Sbjct:   54 CVICKNVLTDPVQTSCGCRYCRSCIVKHLSFSSYCCNDSE-DCRNELLELETNIRTDAAASRFIKALKVKCTTKDCEYITTLENINSHRNECLFVIVECDQCSKKFTRNYLLTHKKIECEKRKEICQFCGISFPLEILPLIHNNIHHRDLCVKYLSLCPYKCGMKEEISLVEHRKICFSKPFLCPYIEVGCDYLFFTVD-LNKHMELNSINHFSCLIDRLYLMESCLGELQSQAHRETDSLKKLITFDFDKDYSRHLSQLQ-ILSETKNQSVKCTLD-----DTVFKNGNYIWHIKEFSVLKEEAKADRIASICSDPFYTGEFGYKLCMKIYPNGDGLGKQTHLSVFFTIMRGEYDPILVWPFRNKVTLSILDQISKKNHYSETFLPDIKLICFHKPTADFNVASGSPKFITFSNLEN---YIVNNGFFLKISV 476