DnaJ homolog subfamily C member 5

Overview
NameDnaJ homolog subfamily C member 5
Smed IDSMED30026529
Length (bp)1055
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DnaJ homolog subfamily C member 5 (SMED30026529) t-SNE clustered cells

Violin plots show distribution of expression levels for DnaJ homolog subfamily C member 5 (SMED30026529) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DnaJ homolog subfamily C member 5 (SMED30026529) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DnaJ homolog subfamily C member 5 (SMED30026529) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30026529

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30026529h1SMcG0009978 Contig2341GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
nervous systemSMED30026529h1SMcG0009978 dd_Smed_v4_2840_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30026529h1SMcG0009978 dd_Smed_v4_2840_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30026529h1SMcG0009978 dd_Smed_v4_2840_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Human
Match: DNAJC5B (DnaJ heat shock protein family (Hsp40) member C5 beta [Source:HGNC Symbol;Acc:HGNC:24138])

HSP 1 Score: 98.2117 bits (243), Expect = 1.186e-23
Identity = 47/89 (52.81%), Postives = 59/89 (66.29%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            +IKK+YR+LALK HPDKN +D  ATEKF+ +N A+++L D  KR+ YDKYGSLGL    Q G+EN       +    KAL V   LLTG
Sbjct:   34 EIKKTYRKLALKHHPDKNPDDPAATEKFKEINNAHAILTDISKRSIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKALFVIVGLLTG 122
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Human
Match: DNAJC5 (DnaJ heat shock protein family (Hsp40) member C5 [Source:HGNC Symbol;Acc:HGNC:16235])

HSP 1 Score: 92.4337 bits (228), Expect = 1.389e-21
Identity = 43/82 (52.44%), Postives = 55/82 (67.07%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLV 381
            DIKKSYR+LALK+HPDKN ++ +A +KF+ +N A+++L D  KR  YDKYGSLGL    Q GEEN       +    KAL V
Sbjct:   30 DIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFV 111
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Human
Match: DNAJC5 (DnaJ heat shock protein family (Hsp40) member C5 [Source:HGNC Symbol;Acc:HGNC:16235])

HSP 1 Score: 91.6633 bits (226), Expect = 1.420e-21
Identity = 43/82 (52.44%), Postives = 55/82 (67.07%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLV 381
            DIKKSYR+LALK+HPDKN ++ +A +KF+ +N A+++L D  KR  YDKYGSLGL    Q GEEN       +    KAL V
Sbjct:   30 DIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFV 111
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Human
Match: DNAJC5B (DnaJ heat shock protein family (Hsp40) member C5 beta [Source:HGNC Symbol;Acc:HGNC:24138])

HSP 1 Score: 82.0333 bits (201), Expect = 5.979e-19
Identity = 37/63 (58.73%), Postives = 48/63 (76.19%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGE 324
            +IKK+YR+LALK HPDKN +D  ATEKF+ +N A+++L D  KR+ YDKYGSLGL    Q G+
Sbjct:   34 EIKKTYRKLALKHHPDKNPDDPAATEKFKEINNAHAILTDISKRSIYDKYGSLGLYVAEQFGD 96
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Human
Match: DNAJC5G (DnaJ heat shock protein family (Hsp40) member C5 gamma [Source:HGNC Symbol;Acc:HGNC:24844])

HSP 1 Score: 78.1814 bits (191), Expect = 1.103e-16
Identity = 35/82 (42.68%), Postives = 51/82 (62.20%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLV 381
            D KKSYR+LAL++HPDKN  +  A E F+ +N A+++L D KKR  YD++GSLG+      GEE  ++         K L++
Sbjct:   32 DFKKSYRKLALRYHPDKNPGNAQAAEIFKEINAAHAILSDSKKRKIYDQHGSLGIYLYDHFGEEGVRYYFILNSCWFKTLVI 113
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Celegans
Match: dnj-14 (DNaJ domain (Prokaryotic heat shock protein) [Source:UniProtKB/TrEMBL;Acc:E5QCE7])

HSP 1 Score: 73.9442 bits (180), Expect = 3.933e-15
Identity = 40/91 (43.96%), Postives = 56/91 (61.54%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKN-SNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENA--QFLLKSAHPCVKALLVATCLLT 399
            +IKK+YR+LAL++HPDKN   D + TE F+ +N A +VL +  KR  YD+ G  GL+ + Q GE+    Q++LK   P  K    A  LLT
Sbjct:   53 EIKKAYRKLALRYHPDKNLDGDPEKTEMFKEINYANAVLSNPNKRRVYDEMGETGLKLMEQFGEDEKILQWMLK---PWFKWTFFAFGLLT 140
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Celegans
Match: dnj-14 (DNaJ domain (Prokaryotic heat shock protein) [Source:UniProtKB/TrEMBL;Acc:E5QCE7])

HSP 1 Score: 73.559 bits (179), Expect = 4.193e-15
Identity = 40/91 (43.96%), Postives = 56/91 (61.54%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKN-SNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENA--QFLLKSAHPCVKALLVATCLLT 399
            +IKK+YR+LAL++HPDKN   D + TE F+ +N A +VL +  KR  YD+ G  GL+ + Q GE+    Q++LK   P  K    A  LLT
Sbjct:   53 EIKKAYRKLALRYHPDKNLDGDPEKTEMFKEINYANAVLSNPNKRRVYDEMGETGLKLMEQFGEDEKILQWMLK---PWFKWTFFAFGLLT 140
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Celegans
Match: dnj-20 (DnaJ homolog dnj-20 [Source:UniProtKB/Swiss-Prot;Acc:Q8MPX3])

HSP 1 Score: 67.3958 bits (163), Expect = 2.802e-12
Identity = 30/59 (50.85%), Postives = 44/59 (74.58%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGL 300
             N   IKK+YR+LA + HPD+N +D+ A EKF++++ AY VL DK+KRA YD++G  G+
Sbjct:   35 ANANQIKKAYRKLAKELHPDRNQDDEMANEKFQDLSSAYEVLSDKEKRAMYDRHGEEGV 93
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Celegans
Match: dnj-16 (DNaJ domain (Prokaryotic heat shock protein) [Source:UniProtKB/TrEMBL;Acc:Q22028])

HSP 1 Score: 66.2402 bits (160), Expect = 8.220e-12
Identity = 31/55 (56.36%), Postives = 40/55 (72.73%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYG 288
             +EA+IK +YR+LALK+HPD+N ND  A E+F+ V+ AYSVL D  KR  YD  G
Sbjct:   45 ASEAEIKSAYRKLALKYHPDRNPNDAHAQEEFKKVSIAYSVLSDPNKRRQYDVSG 99
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Celegans
Match: dnj-16 (DNaJ domain (Prokaryotic heat shock protein) [Source:UniProtKB/TrEMBL;Acc:Q22028])

HSP 1 Score: 65.855 bits (159), Expect = 8.635e-12
Identity = 31/55 (56.36%), Postives = 40/55 (72.73%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYG 288
             +EA+IK +YR+LALK+HPD+N ND  A E+F+ V+ AYSVL D  KR  YD  G
Sbjct:   28 ASEAEIKSAYRKLALKYHPDRNPNDAHAQEEFKKVSIAYSVLSDPNKRRQYDVSG 82
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Fly
Match: Csp (gene:FBgn0004179 transcript:FBtr0078493)

HSP 1 Score: 103.605 bits (257), Expect = 8.797e-26
Identity = 46/89 (51.69%), Postives = 62/89 (69.66%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK+YR+LALK+HPDKN ++ DA +KF+ VN+A+S+L D+ KR  YD YGSLGL    Q GEEN         P VKA+++   ++TG
Sbjct:   32 DIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITG 120
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Fly
Match: Csp (gene:FBgn0004179 transcript:FBtr0078495)

HSP 1 Score: 103.605 bits (257), Expect = 1.059e-25
Identity = 46/89 (51.69%), Postives = 62/89 (69.66%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK+YR+LALK+HPDKN ++ DA +KF+ VN+A+S+L D+ KR  YD YGSLGL    Q GEEN         P VKA+++   ++TG
Sbjct:   32 DIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITG 120
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Fly
Match: Csp (gene:FBgn0004179 transcript:FBtr0334747)

HSP 1 Score: 103.605 bits (257), Expect = 1.255e-25
Identity = 46/89 (51.69%), Postives = 62/89 (69.66%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK+YR+LALK+HPDKN ++ DA +KF+ VN+A+S+L D+ KR  YD YGSLGL    Q GEEN         P VKA+++   ++TG
Sbjct:   32 DIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITG 120
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Fly
Match: Csp (gene:FBgn0004179 transcript:FBtr0334746)

HSP 1 Score: 103.605 bits (257), Expect = 1.255e-25
Identity = 46/89 (51.69%), Postives = 62/89 (69.66%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK+YR+LALK+HPDKN ++ DA +KF+ VN+A+S+L D+ KR  YD YGSLGL    Q GEEN         P VKA+++   ++TG
Sbjct:   32 DIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITG 120
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Fly
Match: Csp (gene:FBgn0004179 transcript:FBtr0344983)

HSP 1 Score: 103.605 bits (257), Expect = 1.485e-25
Identity = 46/89 (51.69%), Postives = 62/89 (69.66%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK+YR+LALK+HPDKN ++ DA +KF+ VN+A+S+L D+ KR  YD YGSLGL    Q GEEN         P VKA+++   ++TG
Sbjct:   32 DIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITG 120
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Zebrafish
Match: dnajc5ab (DnaJ (Hsp40) homolog, subfamily C, member 5ab [Source:ZFIN;Acc:ZDB-GENE-081021-2])

HSP 1 Score: 96.6709 bits (239), Expect = 2.550e-23
Identity = 46/91 (50.55%), Postives = 59/91 (64.84%), Query Frame = 1 
Query:  130 EADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            + DIKKSYR+LALKFHPDKN N+ +A +KF+ +N A+++L D  KR  YDKYGSLGL    Q GEEN       +    KAL +   + TG
Sbjct:   29 QEDIKKSYRKLALKFHPDKNPNNPEAADKFKEINNAHAILSDPTKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFIFCGVATG 119
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Zebrafish
Match: dnajc5ab (DnaJ (Hsp40) homolog, subfamily C, member 5ab [Source:ZFIN;Acc:ZDB-GENE-081021-2])

HSP 1 Score: 96.6709 bits (239), Expect = 2.550e-23
Identity = 46/91 (50.55%), Postives = 59/91 (64.84%), Query Frame = 1 
Query:  130 EADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            + DIKKSYR+LALKFHPDKN N+ +A +KF+ +N A+++L D  KR  YDKYGSLGL    Q GEEN       +    KAL +   + TG
Sbjct:   29 QEDIKKSYRKLALKFHPDKNPNNPEAADKFKEINNAHAILSDPTKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFIFCGVATG 119
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Zebrafish
Match: dnajc5b (DnaJ (Hsp40) homolog, subfamily C, member 5 beta [Source:ZFIN;Acc:ZDB-GENE-050413-1])

HSP 1 Score: 95.5153 bits (236), Expect = 5.496e-23
Identity = 47/92 (51.09%), Postives = 57/92 (61.96%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLT 399
            C   DIK+SYR+LALK+HPDKN  + DAT+KF+ +N A++VL D  KR  YDKYGSLGL    Q GEEN       +    K L     LLT
Sbjct:   26 CTHDDIKRSYRKLALKYHPDKNPENPDATDKFKELNNAHAVLSDVTKRNIYDKYGSLGLYVSQQFGEENVNTYFMLSSWWAKGLFAICGLLT 117
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Zebrafish
Match: dnajc5b (DnaJ (Hsp40) homolog, subfamily C, member 5 beta [Source:ZFIN;Acc:ZDB-GENE-050413-1])

HSP 1 Score: 95.5153 bits (236), Expect = 5.496e-23
Identity = 47/92 (51.09%), Postives = 57/92 (61.96%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLT 399
            C   DIK+SYR+LALK+HPDKN  + DAT+KF+ +N A++VL D  KR  YDKYGSLGL    Q GEEN       +    K L     LLT
Sbjct:   26 CTHDDIKRSYRKLALKYHPDKNPENPDATDKFKELNNAHAVLSDVTKRNIYDKYGSLGLYVSQQFGEENVNTYFMLSSWWAKGLFAICGLLT 117
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Zebrafish
Match: dnajc5aa (DnaJ (Hsp40) homolog, subfamily C, member 5aa [Source:ZFIN;Acc:ZDB-GENE-031113-20])

HSP 1 Score: 93.2041 bits (230), Expect = 4.897e-22
Identity = 45/89 (50.56%), Postives = 58/89 (65.17%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKKSYR+LALK+HPDKN ++ +A +KF+ +N A+++L D  KR  YDKYGSLGL    Q GEEN       +    KAL +   L TG
Sbjct:   31 DIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILNDPTKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFIFCGLATG 119
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Xenopus
Match: diras1 (DIRAS family GTP binding RAS like 1 [Source:Xenbase;Acc:XB-GENE-489505])

HSP 1 Score: 88.5817 bits (218), Expect = 2.304e-20
Identity = 52/116 (44.83%), Postives = 74/116 (63.79%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTGXXXXXXXXXXXXXXXXXGKCAPDEQDD 483
            +IKK+YR+LAL++HPDKN ++ +A EKF+ +N A+S L D+ KR  YD+YGS+GL    Q G+E+ ++    +    KALLV     +       C C CC  FCCG+C P E+DD
Sbjct:   32 EIKKAYRKLALRYHPDKNPDNPEAAEKFKEINNAHSTLSDENKRKMYDEYGSMGLYVAEQFGDESVKYYFLMSKCWFKALLVCCFFSS------CCCCCCCCLFCCGRCKPPEEDD 141
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Xenopus
Match: diras1 (DIRAS family GTP binding RAS like 1 [Source:Xenbase;Acc:XB-GENE-489505])

HSP 1 Score: 88.1965 bits (217), Expect = 8.244e-20
Identity = 52/116 (44.83%), Postives = 74/116 (63.79%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTGXXXXXXXXXXXXXXXXXGKCAPDEQDD 483
            +IKK+YR+LAL++HPDKN ++ +A EKF+ +N A+S L D+ KR  YD+YGS+GL    Q G+E+ ++    +    KALLV         +   C C CC  FCCG+C P E+DD
Sbjct:   32 EIKKAYRKLALRYHPDKNPDNPEAAEKFKEINNAHSTLSDENKRKMYDEYGSMGLYVAEQFGDESVKYYFLMSKCWFKALLVCC------FFSSCCCCCCCCLFCCGRCKPPEEDD 141
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Xenopus
Match: DNAJC5B (DnaJ heat shock protein family (Hsp40) member C5 beta [Source:NCBI gene;Acc:100379708])

HSP 1 Score: 85.8853 bits (211), Expect = 2.563e-19
Identity = 46/90 (51.11%), Postives = 57/90 (63.33%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEE--NAQFLLKSAHPCVKALLVATCLLT 399
            +IKKSYR+LALK HPDKN ++  A + F+ +N A+++L D  KR  YDKYGSLGL    Q GEE  NA F+L S     K L     LLT
Sbjct:   30 EIKKSYRKLALKHHPDKNPDNPQAADTFKEINNAHAILSDVSKRNIYDKYGSLGLYVAEQFGEENVNAYFMLSSW--WAKGLFALCGLLT 117
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Xenopus
Match: chd9 (chromodomain helicase DNA binding protein 9 [Source:Xenbase;Acc:XB-GENE-1217623])

HSP 1 Score: 70.0922 bits (170), Expect = 9.085e-13
Identity = 34/60 (56.67%), Postives = 46/60 (76.67%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQ 303
             NE +IKK+YR++ALK+HPDKN  D +A +KF+ + +AY VL D KKRA YD+YG  GL+
Sbjct:   74 ANEDEIKKAYRKMALKYHPDKN-KDANAEDKFKEIAEAYDVLSDPKKRAVYDQYGEEGLK 132
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Xenopus
Match: dnajb11 (DnaJ heat shock protein family (Hsp40) member B11 [Source:NCBI gene;Acc:394787])

HSP 1 Score: 66.6254 bits (161), Expect = 7.835e-12
Identity = 30/56 (53.57%), Postives = 43/56 (76.79%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQ 303
            +IKK+YR+LAL+ HPD+N +D +A EKF+++  AY VL D++KR  YD YG  GL+
Sbjct:    2 EIKKAYRKLALQLHPDRNPDDPNAQEKFQDLGAAYEVLSDEEKRKQYDTYGEEGLK 57
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Mouse
Match: Dnajc5b (DnaJ heat shock protein family (Hsp40) member C5 beta [Source:MGI Symbol;Acc:MGI:1913576])

HSP 1 Score: 93.2041 bits (230), Expect = 5.749e-22
Identity = 43/89 (48.31%), Postives = 56/89 (62.92%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            +IKK+YR+LAL+ HPDKN +D  A EKF+ +N A+++L D  KR  YDKYGSLGL    Q G+EN       +    K L +   LLTG
Sbjct:   34 EIKKTYRKLALRHHPDKNPDDPSAAEKFKEINNAHTILTDTSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTG 122
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Mouse
Match: Dnajc5b (DnaJ heat shock protein family (Hsp40) member C5 beta [Source:MGI Symbol;Acc:MGI:1913576])

HSP 1 Score: 93.2041 bits (230), Expect = 5.749e-22
Identity = 43/89 (48.31%), Postives = 56/89 (62.92%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            +IKK+YR+LAL+ HPDKN +D  A EKF+ +N A+++L D  KR  YDKYGSLGL    Q G+EN       +    K L +   LLTG
Sbjct:   34 EIKKTYRKLALRHHPDKNPDDPSAAEKFKEINNAHTILTDTSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTG 122
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Mouse
Match: Dnajc5b (DnaJ heat shock protein family (Hsp40) member C5 beta [Source:MGI Symbol;Acc:MGI:1913576])

HSP 1 Score: 93.2041 bits (230), Expect = 5.749e-22
Identity = 43/89 (48.31%), Postives = 56/89 (62.92%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            +IKK+YR+LAL+ HPDKN +D  A EKF+ +N A+++L D  KR  YDKYGSLGL    Q G+EN       +    K L +   LLTG
Sbjct:   34 EIKKTYRKLALRHHPDKNPDDPSAAEKFKEINNAHTILTDTSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTG 122
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Mouse
Match: Dnajc5b (DnaJ heat shock protein family (Hsp40) member C5 beta [Source:MGI Symbol;Acc:MGI:1913576])

HSP 1 Score: 93.2041 bits (230), Expect = 5.749e-22
Identity = 43/89 (48.31%), Postives = 56/89 (62.92%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            +IKK+YR+LAL+ HPDKN +D  A EKF+ +N A+++L D  KR  YDKYGSLGL    Q G+EN       +    K L +   LLTG
Sbjct:   34 EIKKTYRKLALRHHPDKNPDDPSAAEKFKEINNAHTILTDTSKRNIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKTLFIIIGLLTG 122
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Mouse
Match: Dnajc5 (DnaJ heat shock protein family (Hsp40) member C5 [Source:MGI Symbol;Acc:MGI:892995])

HSP 1 Score: 91.2781 bits (225), Expect = 6.928e-22
Identity = 43/83 (51.81%), Postives = 55/83 (66.27%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVA 384
            DIKKSYR+LALK+HPDKN ++ +A +KF+ +N A+++L D  KR  YDKYGSLGL    Q GEEN       +    KAL V 
Sbjct:   30 DIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVV 112
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. UniProt/SwissProt
Match: sp|Q03751|DNJC5_DROME (DnaJ homolog subfamily C member 5 homolog OS=Drosophila melanogaster OX=7227 GN=Csp PE=1 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 6.152e-24
Identity = 45/89 (50.56%), Postives = 62/89 (69.66%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK+YR+LALK+HPDKN ++ DA +KF+ VN+A+S+L ++ KR  YD YGSLGL    Q GEEN         P VKA+++   ++TG
Sbjct:   32 DIKKTYRKLALKYHPDKNPDNVDAADKFKEVNRAHSILSNQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKAVVICCAVITG 120
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. UniProt/SwissProt
Match: sp|P56101|DNJC5_TETCF (DnaJ homolog subfamily C member 5 OS=Tetronarce californica OX=7787 GN=dnajc5 PE=1 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 3.365e-23
Identity = 46/89 (51.69%), Postives = 60/89 (67.42%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKKSYR+LALK+HPDKN ++ +A+EKF+ +N A+++L D  KR  YDKYGSLGL    Q GEEN       +    KAL V   ++TG
Sbjct:   30 DIKKSYRKLALKYHPDKNPDNPEASEKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGVITG 118
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. UniProt/SwissProt
Match: sp|Q9UF47|DNJ5B_HUMAN (DnaJ homolog subfamily C member 5B OS=Homo sapiens OX=9606 GN=DNAJC5B PE=1 SV=2)

HSP 1 Score: 98.2117 bits (243), Expect = 5.695e-23
Identity = 47/89 (52.81%), Postives = 59/89 (66.29%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            +IKK+YR+LALK HPDKN +D  ATEKF+ +N A+++L D  KR+ YDKYGSLGL    Q G+EN       +    KAL V   LLTG
Sbjct:   34 EIKKTYRKLALKHHPDKNPDDPAATEKFKEINNAHAILTDISKRSIYDKYGSLGLYVAEQFGDENVNTYFMLSSWWAKALFVIVGLLTG 122
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. UniProt/SwissProt
Match: sp|F1RTY8|DNJ5B_PIG (DnaJ homolog subfamily C member 5B OS=Sus scrofa OX=9823 GN=DNAJC5B PE=3 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 3.779e-22
Identity = 46/89 (51.69%), Postives = 56/89 (62.92%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            +IKK+YR+LALK HPDKN +D  A EKF+ +N A+++L D  KR  YDKYGSLGL    Q GEEN       +    K L V   LLTG
Sbjct:   34 EIKKTYRKLALKHHPDKNPDDPGAAEKFKEINNAHTILTDMSKRNIYDKYGSLGLYVAEQFGEENVNTYFMLSSWWAKTLFVIIGLLTG 122
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. UniProt/SwissProt
Match: sp|O42196|DNJC5_XENLA (DnaJ homolog subfamily C member 5 OS=Xenopus laevis OX=8355 GN=dnajc5 PE=2 SV=1)

HSP 1 Score: 94.7449 bits (234), Expect = 8.676e-22
Identity = 45/89 (50.56%), Postives = 58/89 (65.17%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK YR+LALK+HPDKN ++ +A+EKF+ +N A+ +L D  KR  YDKYGSLGL    Q GEEN       +    KAL +   L+TG
Sbjct:   30 DIKKCYRKLALKYHPDKNPDNPEASEKFKEINNAHGILADSTKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFMFCGLITG 118
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. TrEMBL
Match: A0A034UZ50 (Cysteine string protein (Fragment) OS=Bactrocera dorsalis OX=27457 GN=CSP PE=4 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 3.873e-25
Identity = 50/89 (56.18%), Postives = 62/89 (69.66%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK+YR+LALK+HPDKN N+ DA EKF+ VN+A+S+L D+ KR  YD YGSLGL    Q GEEN         P VKAL++   +LTG
Sbjct:   33 DIKKTYRKLALKYHPDKNPNNTDAAEKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKALVICCTILTG 121
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. TrEMBL
Match: A0A0X3PW34 (J domain-containing protein OS=Schistocephalus solidus OX=70667 GN=TR114016 PE=4 SV=1)

HSP 1 Score: 110.538 bits (275), Expect = 7.413e-25
Identity = 49/89 (55.06%), Postives = 68/89 (76.40%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            D++K+YR+LAL+ HPDKN +D +A EKF  +N+A+++L D+ KRAFYDKYGS GL    QMGEENA+  L+  +PC++ LLV   +LTG
Sbjct:   43 DVRKAYRKLALRCHPDKNPDDPNAGEKFAEINRAHAILSDESKRAFYDKYGSFGLFMADQMGEENAELYLRLNNPCLRCLLVTCFILTG 131
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. TrEMBL
Match: A0A5E4NN48 (J domain-containing protein OS=Cinara cedri OX=506608 GN=CINCED_3A019328 PE=4 SV=1)

HSP 1 Score: 109.768 bits (273), Expect = 9.027e-25
Identity = 66/147 (44.90%), Postives = 88/147 (59.86%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTGXXXXXXXXXXXXXXXXXGKCAPDEQDDLGDPLTERMDLETGDPPENVIITQPCDANAS 576
            +IK++YR+LALK+HPDKN+ + +A EKF+ +NKAY +L D +KR  YD YGSLGL    Q GEEN            KAL++ +CL+TG   CC   C CC NFC GK  P E +D     T   +    D  ++V++ QP   NAS
Sbjct:   27 EIKRTYRKLALKYHPDKNTGNPEAEEKFKEINKAYRILTDPRKRNIYDNYGSLGLYIAEQFGEENVNTYFFVTSKWCKALIIGSCLITG--CCCCFCCCCCCNFCFGKFKPKEPEDQQANYTNLHE----DSEDDVVVNQPSSTNAS 167
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. TrEMBL
Match: A0A0K8VC57 (Cysteine string protein OS=Bactrocera latifrons OX=174628 GN=Csp_2 PE=4 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 9.969e-25
Identity = 50/89 (56.18%), Postives = 62/89 (69.66%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK+YR+LALK+HPDKN N+ DA EKF+ VN+A+S+L D+ KR  YD YGSLGL    Q GEEN         P VKAL++   +LTG
Sbjct:   33 DIKKTYRKLALKYHPDKNPNNTDAAEKFKEVNRAHSILSDQTKRNIYDNYGSLGLYIAEQFGEENVNAYFVVTSPAVKALVICCTILTG 121
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. TrEMBL
Match: A0A0X3PDG7 (Cysteine string protein OS=Schistocephalus solidus OX=70667 GN=CSP PE=4 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 1.081e-24
Identity = 49/89 (55.06%), Postives = 68/89 (76.40%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            D++K+YR+LAL+ HPDKN +D +A EKF  +N+A+++L D+ KRAFYDKYGS GL    QMGEENA+  L+  +PC++ LLV   +LTG
Sbjct:   43 DVRKAYRKLALRCHPDKNPDDPNAGEKFAEINRAHAILSDESKRAFYDKYGSFGLFMADQMGEENAELYLRLNNPCLRCLLVTCFILTG 131
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Cavefish
Match: dnajc5b (DnaJ heat shock protein family (Hsp40) member C5 beta [Source:NCBI gene;Acc:103044825])

HSP 1 Score: 95.5153 bits (236), Expect = 4.706e-23
Identity = 48/92 (52.17%), Postives = 56/92 (60.87%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLT 399
            C   DIKKSYR+LALK+HPDKN  + +A EKF+ +N A+SVL D  KR  YDKYGSLGL    Q GEEN       +    K L     LLT
Sbjct:   26 CTHDDIKKSYRKLALKYHPDKNPENPEAAEKFKELNNAHSVLSDVTKRNIYDKYGSLGLYVSQQFGEENVNTYFMLSSWWAKGLFAICGLLT 117
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Cavefish
Match: dnajc5ab (dnaJ homolog subfamily C member 5-like [Source:NCBI gene;Acc:103028766])

HSP 1 Score: 95.1301 bits (235), Expect = 7.647e-23
Identity = 45/89 (50.56%), Postives = 58/89 (65.17%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK YR+LALKFHPDKN ++ +A EKF+ +N A+++LID  KR  YD+YGSLGL    Q GEEN       +    KAL +   + TG
Sbjct:   31 DIKKCYRKLALKFHPDKNPDNPEAAEKFKEINNAHAILIDPTKRNIYDQYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFIFCGVATG 119
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Cavefish
Match: dnajc5b (DnaJ heat shock protein family (Hsp40) member C5 beta [Source:NCBI gene;Acc:103044825])

HSP 1 Score: 95.1301 bits (235), Expect = 9.291e-23
Identity = 48/92 (52.17%), Postives = 56/92 (60.87%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLT 399
            C   DIKKSYR+LALK+HPDKN  + +A EKF+ +N A+SVL D  KR  YDKYGSLGL    Q GEEN       +    K L     LLT
Sbjct:   26 CTHDDIKKSYRKLALKYHPDKNPENPEAAEKFKELNNAHSVLSDVTKRNIYDKYGSLGLYVSQQFGEENVNTYFMLSSWWAKGLFAICGLLT 117
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Cavefish
Match: dnajc5aa (dnaJ homolog subfamily C member 5 [Source:NCBI gene;Acc:103036084])

HSP 1 Score: 94.3597 bits (233), Expect = 1.691e-22
Identity = 46/89 (51.69%), Postives = 58/89 (65.17%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKKSYR+LALK+HPDKN ++ +A +KF+ +N A+++L D  KR  YDKYGSLGL    Q GEEN       +    KAL V   L TG
Sbjct:   31 DIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILNDPTKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLATG 119
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Cavefish
Match: dnajc5gb (dnaJ homolog subfamily C member 5-like [Source:NCBI gene;Acc:103030357])

HSP 1 Score: 86.2705 bits (212), Expect = 2.667e-19
Identity = 58/149 (38.93%), Postives = 88/149 (59.06%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTGXXXXXXXXXXXXXXXXXGKCAPDEQDDLG-DP--LTERMDLETGDPPENVIITQPCDANA 573
            +IKKSYR+LAL++HPDKN ++ +A ++F+ +N A ++L D+ KR  YD+YGS+GL    Q G+++ ++    +    K L+V   + T       C CFCC  FCCGKC   E+++   DP  L  +M  E     E  II QP  ++A
Sbjct:   32 EIKKSYRKLALRYHPDKNPDNPEAADRFKEINNANTILNDEHKRQIYDEYGSMGLYIADQFGDDSVKYYFLMSKCWFKTLVVCGMIFT------CCCCFCCCCFCCGKCGTKEEEEFYIDPEQLEAQMFEEQNTANEPAIIGQPIPSSA 174
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Sea Lamprey
Match: dnajc5aa (DnaJ (Hsp40) homolog, subfamily C, member 5aa [Source:ZFIN;Acc:ZDB-GENE-031113-20])

HSP 1 Score: 86.2705 bits (212), Expect = 1.616e-20
Identity = 41/88 (46.59%), Postives = 56/88 (63.64%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLT 399
            +IKKSYR+LALK+HPDKN ++ +A EKF+ +N A  +L D KKR  YD+YGSLGL    Q GE+N       +    K+L +    +T
Sbjct:   31 EIKKSYRKLALKYHPDKNPDNPEAVEKFKEINNANGILSDLKKRNIYDQYGSLGLYVAEQFGEDNVHTYFMFSSWWAKSLFLFCGAIT 118
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Sea Lamprey
Match: dnajc10 (DnaJ (Hsp40) homolog, subfamily C, member 10 [Source:ZFIN;Acc:ZDB-GENE-070327-1])

HSP 1 Score: 67.0106 bits (162), Expect = 2.204e-12
Identity = 31/55 (56.36%), Postives = 41/55 (74.55%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGL 300
            DI+K++++LAL  HPDKN +D DA EKF  +N+AY VL D++ R  YDKYG  GL
Sbjct:   51 DIRKAFKKLALTLHPDKNQDDPDAHEKFLKINRAYEVLKDEELRKKYDKYGEKGL 105
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001704.1 (pep scaffold:Pmarinus_7.0:GL487204:33:3976:-1 gene:ENSPMAG00000001540.1 transcript:ENSPMAT00000001704.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 1.905e-11
Identity = 31/68 (45.59%), Postives = 47/68 (69.12%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNS-NDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGE 324
             ++ ++KK+YRRLAL++HPDKN+ N ++ATE F+ +  AY VL D ++RA+YD +    LQ     GE
Sbjct:   14 ASDEELKKAYRRLALQWHPDKNADNVEEATETFKLIQAAYDVLSDAQERAWYDAHREAILQGAMSGGE 81
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Sea Lamprey
Match: dnaja3b (DnaJ heat shock protein family (Hsp40) member A3b [Source:ZFIN;Acc:ZDB-GENE-040115-3])

HSP 1 Score: 61.6178 bits (148), Expect = 6.379e-11
Identity = 31/57 (54.39%), Postives = 37/57 (64.91%), Query Frame = 1 
Query:  130 EADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGL 300
            + DIKKSY +LA K+HPD N +D  A EKF  + +AY VL D  KR  YD YGS G 
Sbjct:   26 QKDIKKSYYQLAKKYHPDTNKDDPKAKEKFAELAEAYEVLSDDAKRKQYDTYGSAGF 82
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Sea Lamprey
Match: DNAJA4 (DnaJ heat shock protein family (Hsp40) member A4 [Source:HGNC Symbol;Acc:HGNC:14885])

HSP 1 Score: 61.6178 bits (148), Expect = 6.963e-11
Identity = 29/56 (51.79%), Postives = 41/56 (73.21%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQ 303
            ++KK+YR+LALK+HPDKN N+    EKF+ +++AY VL+D KKR  YD  G   L+
Sbjct:   21 ELKKAYRKLALKYHPDKNPNE---GEKFKQISQAYEVLLDPKKRELYDMGGEQALK 73
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Yeast
Match: HLJ1 (Co-chaperone for Hsp40p; anchored in the ER membrane; with its homolog Ydj1p promotes ER-associated protein degradation (ERAD) of integral membrane substrates; similar to E. coli DnaJ [Source:SGD;Acc:S000004771])

HSP 1 Score: 60.8474 bits (146), Expect = 2.805e-11
Identity = 27/55 (49.09%), Postives = 43/55 (78.18%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYG 288
              +++IKK+YR+LA+K HPDKNS+ K A E F+ +N+A+ VL +++KR+ YD+ G
Sbjct:   32 ATDSEIKKAYRKLAIKLHPDKNSHPK-AGEAFKVINRAFEVLSNEEKRSIYDRIG 85
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Yeast
Match: SIS1 (Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; shuttles between cytosol and nucleus; mediates delivery of misfolded proteins into the nucleus for degradation; involved in proteasomal degradation of misfolded cytosolic proteins; protein abundance increases in response to DNA replication stress; polyQ aggregates sequester Sis1p and interfere with clearance of misfolded proteins; similar to bacterial DnaJ proteins and mammalian DnaJB1 [Source:SGD;Acc:S000004952])

HSP 1 Score: 61.2326 bits (147), Expect = 5.066e-11
Identity = 27/55 (49.09%), Postives = 40/55 (72.73%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYG 288
             NE ++KK YR+ ALK+HPDK + D   TEKF+ +++A+ +L D +KR  YD+YG
Sbjct:   17 ANEQELKKGYRKAALKYHPDKPTGD---TEKFKEISEAFEILNDPQKREIYDQYG 68
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Yeast
Match: YDJ1 (Type I HSP40 co-chaperone; involved in regulation of HSP90 and HSP70 functions; acts as an adaptor that helps Rsp5p recognize cytosolic misfolded proteins for ubiquitination after heat shock; critical for determining cell size at Start as a function of growth rate; involved in protein translocation across membranes; member of the DnaJ family; chimeric protein in which human p58IPK J domain replaces yeast Ydj1p J domain can complement yeast ydj1 mutant [Source:SGD;Acc:S000005008])

HSP 1 Score: 61.2326 bits (147), Expect = 5.603e-11
Identity = 28/58 (48.28%), Postives = 42/58 (72.41%), Query Frame = 1 
Query:  127 NEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGL 300
             + +IKK+YR+ ALK+HPDKN ++ +A EKF+  + AY +L D +KR  YD++G  GL
Sbjct:   18 TDVEIKKAYRKCALKYHPDKNPSE-EAAEKFKEASAAYEILSDPEKRDIYDQFGEDGL 74
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Yeast
Match: DJP1 (Cytosolic J-domain-containing protein; required for peroxisomal protein import and involved in peroxisome assembly; facilitates import of Mim1p and Mim2p into the mitochondrial outer membrane; homologous to E. coli DnaJ [Source:SGD;Acc:S000001443])

HSP 1 Score: 61.2326 bits (147), Expect = 6.820e-11
Identity = 28/51 (54.90%), Postives = 39/51 (76.47%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYG 288
            +IKK+YR+ +++ HPDKN ND  ATE+F+ +++AY VL D   RA YDKYG
Sbjct:   21 EIKKAYRKKSIQEHPDKNPNDPTATERFQAISEAYQVLGDDDLRAKYDKYG 71
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Yeast
Match: APJ1 (Chaperone with a role in SUMO-mediated protein degradation; member of the DnaJ-like family; conserved across eukaryotes; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; forms nuclear foci upon DNA replication stress [Source:SGD;Acc:S000005021])

HSP 1 Score: 61.2326 bits (147), Expect = 8.070e-11
Identity = 25/53 (47.17%), Postives = 41/53 (77.36%), Query Frame = 1 
Query:  133 ADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGS 291
            ++IKK+YR  ALK+HPDKN++ +++  KF+ + +AY +L D + RA YD+YG+
Sbjct:   20 SEIKKAYRNAALKYHPDKNNHTEESKRKFQEICQAYEILKDNRLRALYDQYGT 72
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Nematostella
Match: EDO37841 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEM8])

HSP 1 Score: 82.4185 bits (202), Expect = 7.908e-20
Identity = 36/64 (56.25%), Postives = 49/64 (76.56%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEE 327
            +IKK+YR++ALK HPDKN ++ +ATEKF+ +N A+S+L D  KR  YDKYG++GL    Q GEE
Sbjct:   18 EIKKAYRKMALKHHPDKNRDNPEATEKFKEINHAHSILSDPSKREIYDKYGNMGLYIAEQFGEE 81
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Nematostella
Match: EDO39725 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9B0])

HSP 1 Score: 71.2478 bits (173), Expect = 7.997e-16
Identity = 34/60 (56.67%), Postives = 46/60 (76.67%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKN-SNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGL 300
             +E D+KK+YRR AL++HPDKN +N + A EKF+ +++AY VL DK+KR  YDKYG  GL
Sbjct:   15 ASEEDVKKAYRRQALRWHPDKNPTNREHAEEKFKKLSEAYEVLSDKEKRDIYDKYGKEGL 74
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Nematostella
Match: EDO35736 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKN4])

HSP 1 Score: 70.0922 bits (170), Expect = 5.460e-14
Identity = 34/60 (56.67%), Postives = 45/60 (75.00%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATE-KFRNVNKAYSVLIDKKKRAFYDKYGSLGL 300
             +E DIKKSYR+LALK+HPDKN  +K+  E KF+ +++AY VL D K+R  YD+YG  GL
Sbjct:   14 ASEQDIKKSYRKLALKWHPDKNPQNKEEAERKFKEISEAYEVLSDSKRRDVYDRYGKDGL 73
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Nematostella
Match: EDO40501 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S6W8])

HSP 1 Score: 63.1586 bits (152), Expect = 9.546e-12
Identity = 31/55 (56.36%), Postives = 42/55 (76.36%), Query Frame = 1 
Query:  139 IKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQ 303
            IKK++R++A+K+HPDKN   KDA EKFR V +AY VL D+ KR  YD++G  GL+
Sbjct:   42 IKKAFRKMAVKYHPDKNKG-KDAEEKFREVAEAYEVLSDENKRRQYDQFGEEGLK 95
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Nematostella
Match: EDO38685 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC61])

HSP 1 Score: 64.3142 bits (155), Expect = 1.075e-11
Identity = 32/60 (53.33%), Postives = 42/60 (70.00%), Query Frame = 1 
Query:  124 CNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQ 303
              +ADIKK YR+L+LK+HPDKN  +  A  KFR   +AY VL D KKRA Y+++G  GL+
Sbjct:   15 ATDADIKKEYRKLSLKYHPDKNQ-EPSAEVKFRQAAEAYDVLSDPKKRAIYNQFGEEGLK 73
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Medaka
Match: dnajc5ab (dnaJ homolog subfamily C member 5 [Source:NCBI gene;Acc:101168851])

HSP 1 Score: 100.908 bits (250), Expect = 5.809e-25
Identity = 48/89 (53.93%), Postives = 58/89 (65.17%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIKK YR+LALKFHPDKN ++ DA EKF+ +N A+S+L+D  K+  YDKYGSLGL    Q GEEN       +    KAL    CL TG
Sbjct:   30 DIKKCYRKLALKFHPDKNPDNPDAAEKFKEINNAHSILVDPTKKNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFAFCCLATG 118
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Medaka
Match: dnajc5aa (dnaJ homolog subfamily C member 5 [Source:NCBI gene;Acc:101169856])

HSP 1 Score: 93.5893 bits (231), Expect = 3.110e-22
Identity = 45/89 (50.56%), Postives = 57/89 (64.04%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTG 402
            DIK+SYR+LALKFHPDKN  + +A +KF+ +N A+++L D  KR  YDKYGSLGL    Q GEEN       +    KAL +   L TG
Sbjct:   31 DIKRSYRKLALKFHPDKNPENPEAADKFKEINNAHAILNDPTKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFIFCGLATG 119
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Medaka
Match: dnajc5ga (DnaJ heat shock protein family (Hsp40) member C5 gamma [Source:NCBI gene;Acc:101166765])

HSP 1 Score: 85.8853 bits (211), Expect = 1.159e-19
Identity = 51/113 (45.13%), Postives = 76/113 (67.26%), Query Frame = 1 
Query:   43 EDNSKASNRKXXXXXXXXXXXXXXXXXCNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLV 381
            E NS    RK+STSG ++Y+ L L K  +  DIKK+YR+LAL++HPDKN ++ +A EKF+ +N A S+L D+ KR  YD+YGS+GL    Q GEE+ ++    +    K+L++
Sbjct:    3 EQNSARPQRKMSTSGESIYKVLGLEKGASAEDIKKAYRKLALRYHPDKNPDNPEAAEKFKEINNANSILNDENKRRVYDEYGSMGLYVSEQFGEESVKYYFLMSKWWFKSLVL 115
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Medaka
Match: DNAJC5B (dnaJ homolog subfamily C member 5 [Source:NCBI gene;Acc:101170215])

HSP 1 Score: 85.8853 bits (211), Expect = 1.695e-19
Identity = 41/88 (46.59%), Postives = 55/88 (62.50%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLT 399
            +IKKSYR+LAL++HPDKN  + +A +KF+ +N A+SVL D  KR  YD YGSLGL    Q GE+N       +    K L +   +LT
Sbjct:   30 EIKKSYRKLALRYHPDKNPENPEAADKFKELNNAHSVLTDLTKRNIYDSYGSLGLYVAQQFGEDNVNTYFMLSTWWAKGLFLLCGILT 117
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Medaka
Match: zgc:122979 (dnaJ homolog subfamily B member 5 [Source:NCBI gene;Acc:101168635])

HSP 1 Score: 73.9442 bits (180), Expect = 3.218e-14
Identity = 35/59 (59.32%), Postives = 47/59 (79.66%), Query Frame = 1 
Query:  127 NEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQ 303
            NE +IKK+YR+LALKFHPDKNS D DA +KF+ + +AY VL D +KR+ YD++G  GL+
Sbjct:   68 NEDEIKKAYRKLALKFHPDKNS-DPDAEDKFKEIAEAYEVLTDPQKRSVYDQFGEEGLK 125
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Planmine SMEST
Match: SMESG000064231.1 (SMESG000064231.1)

HSP 1 Score: 312.383 bits (799), Expect = 2.351e-107
Identity = 190/190 (100.00%), Postives = 190/190 (100.00%), Query Frame = 1 
Query:   31 MSNIEDNSKASNRKXXXXXXXXXXXXXXXXXCNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTGXXXXXXXXXXXXXXXXXGKCAPDEQDDLGDPLTERMDLETGDPPENVIITQPCDANASKASYGTIE 600
            MSNIEDNSKASNRKLSTSGLTLYETLELTKTCNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTGCCYCCFCYCFCCYNFCCGKCAPDEQDDLGDPLTERMDLETGDPPENVIITQPCDANASKASYGTIE
Sbjct:    1 MSNIEDNSKASNRKLSTSGLTLYETLELTKTCNEADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTGCCYCCFCYCFCCYNFCCGKCAPDEQDDLGDPLTERMDLETGDPPENVIITQPCDANASKASYGTIE 190
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Planmine SMEST
Match: SMESG000036889.1 (SMESG000036889.1)

HSP 1 Score: 111.694 bits (278), Expect = 2.275e-29
Identity = 68/131 (51.91%), Postives = 90/131 (68.70%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTGXXXXXXXXXXXXXXXXXGKCAPDEQDDLGDPLTERMDLETGD 528
            +IKK+Y +LAL+FHPDKN  D ++ EKF ++N AY+VL D +KR FYD YGS+GL   + +GE  A+ +LK  +P ++ALLV   L+TGCC+C  CYC CCYNFCCG C P+ Q D     TE +    GD
Sbjct:   33 EIKKAYYKLALQFHPDKNIGDSNSKEKFHSINHAYNVLTDPQKRKFYDSYGSIGLDLFNHVGEHRAEVILKMKNPFIRALLVFGVLITGCCFCYCCYCLCCYNFCCGFCVPNSQIDTVSSETEILKKNDGD 163
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Planmine SMEST
Match: SMESG000054663.1 (SMESG000054663.1)

HSP 1 Score: 111.309 bits (277), Expect = 5.621e-29
Identity = 79/152 (51.97%), Postives = 103/152 (67.76%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQFLLKSAHPCVKALLVATCLLTGXXXXXXXXXXXXXXXXXGKCAPDEQD-DLGDPLTERMDLETGDPPENVIITQPCDANASKASY 588
            +IKK+YR+LALK HPDKN  + +A+EKF+ +N+A SVL+D +KR  YDKYGS GL   +Q+G++ A+F LK  +PCVKALLV  CL +GCCYCC CYCFC   FCCGKCAP + D D+     +  D E  +    V  T+P D  +S   Y
Sbjct:   38 EIKKAYRKLALKCHPDKNPENPNASEKFKEINRANSVLMDSRKRRIYDKYGSFGLNVANQVGDDKAEFFLKFENPCVKALLVLLCLFSGCCYCCCCYCFCFCKFCCGKCAPKDDDVDVEAGFDDIEDNENNENGTTVTNTEPTDKVSSIPDY 189
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Planmine SMEST
Match: SMESG000007139.1 (SMESG000007139.1)

HSP 1 Score: 90.1225 bits (222), Expect = 4.990e-21
Identity = 45/92 (48.91%), Postives = 61/92 (66.30%), Query Frame = 1 
Query:  130 EADIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEENAQ-FLLKSAHPCVKALLVATCLLTG 402
            E D+KK+YR+LALK+HPDKN  + +A+E F+ +NKA  +L D  KR  YDKYGSLGL    Q GE+N   + + S+  C K L +   L+TG
Sbjct:   31 EEDVKKAYRKLALKYHPDKNPGNTNASELFKEINKANRILSDPIKRNIYDKYGSLGLYVAEQFGEDNVHTYFILSSKWC-KGLFIFCGLITG 121
[Close]
BLAST of DnaJ homolog subfamily C member 5 vs. Planmine SMEST
Match: SMESG000017290.1 (SMESG000017290.1)

HSP 1 Score: 67.781 bits (164), Expect = 2.561e-12
Identity = 35/73 (47.95%), Postives = 47/73 (64.38%), Query Frame = 1 
Query:  136 DIKKSYRRLALKFHPDKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQ--FLSQMGEENAQFLLK 348
            +IK +Y +LA K+HPD N N+KDA EKF++ ++AY VL D  K+A YD YGS G Q  F S      A+ L +
Sbjct:   45 EIKSAYYQLAKKYHPDTNKNNKDAEEKFKDASEAYEVLSDTNKKAEYDTYGSAGAQSGFSSNFSRTTAEELFR 117
The following BLAST results are available for this feature:
BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DNAJC5B1.186e-2352.81DnaJ heat shock protein family (Hsp40) member C5 b... [more]
DNAJC51.389e-2152.44DnaJ heat shock protein family (Hsp40) member C5 [... [more]
DNAJC51.420e-2152.44DnaJ heat shock protein family (Hsp40) member C5 [... [more]
DNAJC5B5.979e-1958.73DnaJ heat shock protein family (Hsp40) member C5 b... [more]
DNAJC5G1.103e-1642.68DnaJ heat shock protein family (Hsp40) member C5 g... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnj-143.933e-1543.96DNaJ domain (Prokaryotic heat shock protein) [Sou... [more]
dnj-144.193e-1543.96DNaJ domain (Prokaryotic heat shock protein) [Sou... [more]
dnj-202.802e-1250.85DnaJ homolog dnj-20 [Source:UniProtKB/Swiss-Prot;... [more]
dnj-168.220e-1256.36DNaJ domain (Prokaryotic heat shock protein) [Sou... [more]
dnj-168.635e-1256.36DNaJ domain (Prokaryotic heat shock protein) [Sou... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Csp8.797e-2651.69gene:FBgn0004179 transcript:FBtr0078493[more]
Csp1.059e-2551.69gene:FBgn0004179 transcript:FBtr0078495[more]
Csp1.255e-2551.69gene:FBgn0004179 transcript:FBtr0334747[more]
Csp1.255e-2551.69gene:FBgn0004179 transcript:FBtr0334746[more]
Csp1.485e-2551.69gene:FBgn0004179 transcript:FBtr0344983[more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnajc5ab2.550e-2350.55DnaJ (Hsp40) homolog, subfamily C, member 5ab [Sou... [more]
dnajc5ab2.550e-2350.55DnaJ (Hsp40) homolog, subfamily C, member 5ab [Sou... [more]
dnajc5b5.496e-2351.09DnaJ (Hsp40) homolog, subfamily C, member 5 beta [... [more]
dnajc5b5.496e-2351.09DnaJ (Hsp40) homolog, subfamily C, member 5 beta [... [more]
dnajc5aa4.897e-2250.56DnaJ (Hsp40) homolog, subfamily C, member 5aa [Sou... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
diras12.304e-2044.83DIRAS family GTP binding RAS like 1 [Source:Xenbas... [more]
diras18.244e-2044.83DIRAS family GTP binding RAS like 1 [Source:Xenbas... [more]
DNAJC5B2.563e-1951.11DnaJ heat shock protein family (Hsp40) member C5 b... [more]
chd99.085e-1356.67chromodomain helicase DNA binding protein 9 [Sourc... [more]
dnajb117.835e-1253.57DnaJ heat shock protein family (Hsp40) member B11 ... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dnajc5b5.749e-2248.31DnaJ heat shock protein family (Hsp40) member C5 b... [more]
Dnajc5b5.749e-2248.31DnaJ heat shock protein family (Hsp40) member C5 b... [more]
Dnajc5b5.749e-2248.31DnaJ heat shock protein family (Hsp40) member C5 b... [more]
Dnajc5b5.749e-2248.31DnaJ heat shock protein family (Hsp40) member C5 b... [more]
Dnajc56.928e-2251.81DnaJ heat shock protein family (Hsp40) member C5 [... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q03751|DNJC5_DROME6.152e-2450.56DnaJ homolog subfamily C member 5 homolog OS=Droso... [more]
sp|P56101|DNJC5_TETCF3.365e-2351.69DnaJ homolog subfamily C member 5 OS=Tetronarce ca... [more]
sp|Q9UF47|DNJ5B_HUMAN5.695e-2352.81DnaJ homolog subfamily C member 5B OS=Homo sapiens... [more]
sp|F1RTY8|DNJ5B_PIG3.779e-2251.69DnaJ homolog subfamily C member 5B OS=Sus scrofa O... [more]
sp|O42196|DNJC5_XENLA8.676e-2250.56DnaJ homolog subfamily C member 5 OS=Xenopus laevi... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A034UZ503.873e-2556.18Cysteine string protein (Fragment) OS=Bactrocera d... [more]
A0A0X3PW347.413e-2555.06J domain-containing protein OS=Schistocephalus sol... [more]
A0A5E4NN489.027e-2544.90J domain-containing protein OS=Cinara cedri OX=506... [more]
A0A0K8VC579.969e-2556.18Cysteine string protein OS=Bactrocera latifrons OX... [more]
A0A0X3PDG71.081e-2455.06Cysteine string protein OS=Schistocephalus solidus... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnajc5b4.706e-2352.17DnaJ heat shock protein family (Hsp40) member C5 b... [more]
dnajc5ab7.647e-2350.56dnaJ homolog subfamily C member 5-like [Source:NCB... [more]
dnajc5b9.291e-2352.17DnaJ heat shock protein family (Hsp40) member C5 b... [more]
dnajc5aa1.691e-2251.69dnaJ homolog subfamily C member 5 [Source:NCBI gen... [more]
dnajc5gb2.667e-1938.93dnaJ homolog subfamily C member 5-like [Source:NCB... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnajc5aa1.616e-2046.59DnaJ (Hsp40) homolog, subfamily C, member 5aa [Sou... [more]
dnajc102.204e-1256.36DnaJ (Hsp40) homolog, subfamily C, member 10 [Sour... [more]
ENSPMAT00000001704.11.905e-1145.59pep scaffold:Pmarinus_7.0:GL487204:33:3976:-1 gene... [more]
dnaja3b6.379e-1154.39DnaJ heat shock protein family (Hsp40) member A3b ... [more]
DNAJA46.963e-1151.79DnaJ heat shock protein family (Hsp40) member A4 [... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
HLJ12.805e-1149.09Co-chaperone for Hsp40p; anchored in the ER membra... [more]
SIS15.066e-1149.09Type II HSP40 co-chaperone that interacts with the... [more]
YDJ15.603e-1148.28Type I HSP40 co-chaperone; involved in regulation ... [more]
DJP16.820e-1154.90Cytosolic J-domain-containing protein; required fo... [more]
APJ18.070e-1147.17Chaperone with a role in SUMO-mediated protein deg... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO378417.908e-2056.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO397257.997e-1656.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO357365.460e-1456.67Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO405019.546e-1256.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO386851.075e-1153.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnajc5ab5.809e-2553.93dnaJ homolog subfamily C member 5 [Source:NCBI gen... [more]
dnajc5aa3.110e-2250.56dnaJ homolog subfamily C member 5 [Source:NCBI gen... [more]
dnajc5ga1.159e-1945.13DnaJ heat shock protein family (Hsp40) member C5 g... [more]
DNAJC5B1.695e-1946.59dnaJ homolog subfamily C member 5 [Source:NCBI gen... [more]
zgc:1229793.218e-1459.32dnaJ homolog subfamily B member 5 [Source:NCBI gen... [more]
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BLAST of DnaJ homolog subfamily C member 5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000064231.12.351e-107100.00SMESG000064231.1[more]
SMESG000036889.12.275e-2951.91SMESG000036889.1[more]
SMESG000054663.15.621e-2951.97SMESG000054663.1[more]
SMESG000007139.14.990e-2148.91SMESG000007139.1[more]
SMESG000017290.12.561e-1247.95SMESG000017290.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026529 ID=SMED30026529|Name=DnaJ homolog subfamily C member 5|organism=Schmidtea mediterranea sexual|type=transcript|length=1055bp
ATTTGACCTACACTTTCAAATTTGGTTAAAATGTCAAATATAGAAGATAA
TTCCAAAGCTTCTAATAGGAAATTATCAACAAGTGGATTAACTTTATACG
AAACTTTAGAATTAACTAAAACATGTAACGAAGCAGATATTAAAAAATCT
TATAGACGACTTGCCTTAAAATTTCATCCAGATAAAAATTCAAATGATAA
AGATGCTACAGAGAAATTTCGAAATGTAAATAAAGCTTATTCAGTTTTAA
TTGACAAGAAAAAACGAGCTTTTTATGATAAATATGGATCATTAGGATTG
CAATTTCTATCACAAATGGGTGAAGAAAATGCCCAATTCCTTTTGAAATC
AGCACATCCATGTGTCAAAGCTTTACTTGTTGCAACATGCTTGCTAACCG
GATGTTGTTACTGCTGCTTTTGCTATTGCTTTTGTTGTTACAATTTCTGT
TGTGGAAAATGTGCTCCAGATGAACAGGATGATCTCGGAGATCCTTTAAC
CGAGAGAATGGATCTTGAAACTGGAGATCCCCCTGAAAACGTAATCATTA
CACAACCTTGTGATGCCAATGCATCCAAAGCTTCCTATGGAACAATAGAA
TAATAATAAAAATAATAATAACAATAATCGTTTCCCAATTTAAGGTATTT
GTGTAAAAATTCGCTGTGATAAAATTTACTTATTGATAAAATTTGCCTTA
CACTAAACATGCAATTTATTTTAATTGGTCTGATTTTTTTAAAGGGATTC
TTTAATGTCTTCCCATGTCTATTTAAATTGGTATTATAACTCTCTTTTCT
CTATGTTGTTGGTCTTTGCGATTTATATATTTGGTTACATGTTAAGCAGC
GTTACTACATGGATATATATATGGTAAGCATTGCCGTTATTTTAATAAAT
TGTCTACGGATTTGTACAATTTTTCTAGTTTATCGTGCTCATTGTTCTAT
TTTAATTATCTATTTAAAAAGTAAATCTAAAAAGTAACCTTCTCTGATAA
CCGTGGCAGATTTAGGCTGCATTTTGTGGATTTTATATGCATTAAAGCTT
TCAAA
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protein sequence of SMED30026529-orf-1

>SMED30026529-orf-1 ID=SMED30026529-orf-1|Name=SMED30026529-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=191bp
MSNIEDNSKASNRKLSTSGLTLYETLELTKTCNEADIKKSYRRLALKFHP
DKNSNDKDATEKFRNVNKAYSVLIDKKKRAFYDKYGSLGLQFLSQMGEEN
AQFLLKSAHPCVKALLVATCLLTGCCYCCFCYCFCCYNFCCGKCAPDEQD
DLGDPLTERMDLETGDPPENVIITQPCDANASKASYGTIE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0005829cytosol
GO:0031225anchored component of membrane
GO:0005886plasma membrane
GO:0008021synaptic vesicle
GO:0016020membrane
GO:0043195terminal bouton
GO:0061176type Ib terminal bouton
GO:0061177type Is terminal bouton
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR036869J_dom_sf
IPR001623DnaJ_domain
IPR018253DnaJ_domain_CS
Vocabulary: biological process
TermDefinition
GO:0001964startle response
GO:0006457protein folding
GO:0006887exocytosis
GO:0007269neurotransmitter secretion
GO:0016079synaptic vesicle exocytosis
GO:0016191synaptic vesicle uncoating
GO:0016192vesicle-mediated transport
GO:0031987locomotion involved in locomotory behavior
GO:0048854brain morphogenesis
GO:0070050neuron cellular homeostasis
GO:1900073regulation of neuromuscular synaptic transmission
GO:1903035negative regulation of response to wounding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001623DnaJ domainPRINTSPR00625JDOMAINcoord: 58..78
score: 44.09
coord: 78..97
score: 35.13
coord: 23..41
score: 38.95
coord: 41..56
score: 57.38
IPR001623DnaJ domainSMARTSM00271dnaj_3coord: 20..78
e-value: 1.7E-24
score: 97.4
IPR001623DnaJ domainPFAMPF00226DnaJcoord: 22..83
e-value: 8.9E-24
score: 83.4
IPR001623DnaJ domainPROSITEPS50076DNAJ_2coord: 21..86
score: 21.514
IPR001623DnaJ domainCDDcd06257DnaJcoord: 21..75
e-value: 6.62888E-22
score: 82.2081
IPR036869Chaperone J-domain superfamilyGENE3DG3DSA:1.10.287.110coord: 5..111
e-value: 4.9E-29
score: 102.4
IPR036869Chaperone J-domain superfamilySUPERFAMILYSSF46565Chaperone J-domaincoord: 20..100
NoneNo IPR availablePANTHERPTHR44027FAMILY NOT NAMEDcoord: 9..182
IPR018253DnaJ domain, conserved sitePROSITEPS00636DNAJ_1coord: 63..82