Leucine carboxyl methyltransferase 2

Overview


Name	Leucine carboxyl methyltransferase 2
Smed ID	SMED30026423
Length (bp)	2417

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Leucine carboxyl methyltransferase 2 (SMED30026423) t-SNE clustered cells

Violin plots show distribution of expression levels for Leucine carboxyl methyltransferase 2 (SMED30026423) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Leucine carboxyl methyltransferase 2 (SMED30026423) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Leucine carboxyl methyltransferase 2 (SMED30026423) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30026423

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X2 cell	SMED30026423	SMESG000049235.1	SmedASXL_009155	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30026423	SMESG000049235.1	SmedASXL_009154	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
epidermis	SMED30026423	SMESG000049235.1	dd_Smed_v4_3702_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Human
Match: LCMT2 (leucine carboxyl methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:17558])

HSP 1 Score: 259.225 bits (661), Expect = 4.502e-75
Identity = 223/773 (28.85%), Postives = 349/773 (45.15%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAI---QIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSP---EHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRPGPILIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLIQYHSANQQQQTEEPQFKFGGIKTHYVKADLIAGNGTGNRRQYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMRHIEPARSQLLA--------NSLCGSMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXXXXXXCSGSVVSIG-TDSFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGV-SHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            +Q TND+S LSK S+   GY  D F   ++   +RRAPLI+RGYY+RA+A+ H +  F+E      A    QI SLGAGFD+ +FRL   G+L      E+D+ DVA+RKA  + +  +L   L+ P     P S      +   +++Y ++G+D+ +L  ++  + A+G+    PTL L+E V+TY+  + +A+L+ + A+ F    FV+YEQ+ P D+FG+FM  HF+QL S L G++ +   E Q  R L AGW +  + DM EFY+  + +EE+ R+E++E FDE+EEW LKC HY +L A RG         L+            A  S                    + ++    + + P  K  G  + ++  D+I            L + G+G+      HCR++   +L    +     E   SQ+ +          L  +MTR+S +  ++ GGR SP+ P      LQLH+    +    +                                   A  + D     WRH        ++ YL +YGGRS     LSD +       +W              G V     + S C+        G          S   L P       CG    W  +       PR+SHT+H++            +  VGG+  H +   GVT+I++    +S    +  +DT      +M+HNH S    + +Q+ ++GGGGNCFSFGT  N +  ++DLS++
Sbjct:   13 VQNTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWEVDFPDVARRKAERIGETPELC-ALTGPFERGEPASA-----LCFESADYCILGLDLRQLQRVEEALGAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRGDTL---SHTLVFPSSEAFPRVNPASPSGV------------------FPASVVSSEGQVPNLKRYGHASVFLSPDVI------------LSAGGFGEQ--EGRHCRVSQFHLLSRDCDS----EWKGSQIGSCGTGVQWDGRLYHTMTRLSESRVLVLGGRLSPVSPA--LGVLQLHFFKSEDNNTEDLKVTITK----------------------------AGRKDDSTLCCWRHSTTEVSCQNQEYLFVYGGRSVVEPVLSDWHFLHVGTMAW--------VRIPVEGEVPEARHSHSACTWQGGALIAGGLGASEEPLNSVLFLRPIS-----CGF--LWESVDIQPPITPRYSHTAHVL---------NGKLLLVGGIWIHSSSFPGVTVINLTTGLSS----EYQIDTTYVPWPLMLHNHTSILLPEEQQLLLLGGGGNCFSFGTYFNPHTVTLDLSSL 682

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Human
Match: LCMT1 (leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557])

HSP 1 Score: 166.777 bits (421), Expect = 3.852e-45
Identity = 105/310 (33.87%), Postives = 174/310 (56.13%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLP-FMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYI-----VINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYE--EWLLKCNHYMVLVACRG 1015
            ++GT +++ L K   +  GY++D ++  F+     R+AP INRGY+ R   +  ++  F+   +     QI +LGAG DT+F+RL  +  L +  + E+D+  +  RK        K    LSSP   + LH ++ +     ++++  Y +IG D+  L  L+  ++   ++  LPTL ++ECV+ Y++ ++SA+LLK+ A SF    F+ YEQ+   D FG+ M  + ++    L G++T K+ E Q ERLL  GW++A++ DM E  YN +   E SRIE LE  DE E  E L++  HY +  A +G
Sbjct:   26 VRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKERKAPEINRGYFARVHGVSQLIKAFLRKTEC--HCQIVNLGAGMDTTFWRLKDEDLLPS-KYFEVDFPMIVTRKL----HSIKCKPPLSSP--ILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEEKLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMEL-YNRLPRAEVSRIESLEFLDEMELLEQLMR--HYCLCWATKG 323

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Human
Match: LCMT1 (leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557])

HSP 1 Score: 105.531 bits (262), Expect = 2.139e-24
Identity = 59/139 (42.45%), Postives = 86/139 (61.87%), Query Frame = 2

Query:  605 SYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYE--EWLLKCNHYMVLVACRG 1015
            S  LPTL ++ECV+ Y++ ++SA+LLK+ A SF    F+ YEQ+   D FG+ M  + ++    L G++T K+ E Q ERLL  GW++A++ DM E  YN +   E SRIE LE  DE E  E L++  HY +  A +G
Sbjct:  133 SIKLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQCDLAGVETCKSLESQKERLLSNGWETASAVDMMEL-YNRLPRAEVSRIESLEFLDEMELLEQLMR--HYCLCWATKG 268

HSP 2 Score: 60.4622 bits (145), Expect = 3.051e-9
Identity = 34/108 (31.48%), Postives = 61/108 (56.48%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLP-FMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRK 430
            ++GT +++ L K   +  GY++D ++  F+     R+AP INRGY+ R   +  ++  F+   +     QI +LGAG DT+F+RL  +  L +  + E+D+  +  RK
Sbjct:   26 VRGTCEDASLCKRFAVSIGYWHDPYIQHFVRLSKERKAPEINRGYFARVHGVSQLIKAFLRKTEC--HCQIVNLGAGMDTTFWRLKDEDLLPS-KYFEVDFPMIVTRK 130

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Human
Match: LCMT1 (leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557])

HSP 1 Score: 80.1073 bits (196), Expect = 7.709e-17
Identity = 47/153 (30.72%), Postives = 84/153 (54.90%), Query Frame = 2

Query:  392 FIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYI-----VINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQ 835
            + E+D+  +  RK        K    LSSP   + LH ++ +     ++++  Y +IG D+  L  L+  ++   ++  LPTL ++ECV+ Y++ ++SA+LLK+ A SF    F+ YEQ+   D FG+ M  + ++    L G++T K+ E Q
Sbjct:    8 YFEVDFPMIVTRKL----HSIKCKPPLSSP--ILELHSEDTLQMDGHILDSKRYAVIGADLRDLSELEEKLKKCNMNTQLPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQCDLAGVETCKSLESQ 154

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Human
Match: LCMT1 (leucine carboxyl methyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:17557])

HSP 1 Score: 66.6254 bits (161), Expect = 6.940e-13
Identity = 30/75 (40.00%), Postives = 49/75 (65.33%), Query Frame = 2

Query:  614 LPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQM 838
            LPTL ++ECV+ Y++ ++SA+LLK+ A SF    F+ YEQ+   D FG+ M  + ++    L G++T K+ E Q+
Sbjct:    2 LPTLLIAECVLVYMTPEQSANLLKWAANSFERAMFINYEQVNMGDRFGQIMIENLRRRQCDLAGVETCKSLESQV 76

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Celegans
Match: lcmt-1 (Leucine carboxyl methyltransferase 1 [Source:UniProtKB/Swiss-Prot;Acc:P46554])

HSP 1 Score: 155.606 bits (392), Expect = 1.543e-41
Identity = 106/316 (33.54%), Postives = 160/316 (50.63%), Query Frame = 2

Query:   92 ISNVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFS-----RRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQG-KLDNCTFIELDYFDVAQRK-----AVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVA 1006
            +S+   +Q TND++   K    + GY+ DEF+       S     RR P I+ GY+ R  AIE  +  F+  N+     Q+ SLG GFDT F+RL   G KL    ++E+D+  V  +K       +      L K   S +  VS H D    ++A NY LIG D+ + + LD  +    +S+D+PT+F++ECV+ Y+S   S +LLK I   F +  FV YEQ    D+F + M  +    G  L G++  ++ E Q ER  +AG+      DM + + N +  +E SRI  +E+ DE E       HY V+ A
Sbjct:   25 VSDDYSVQRTNDDATQCKYFATQKGYWKDEFISRFANSSSNVSEARRFPEISMGYWARTAAIEKYVRDFL--NEFDGNAQVVSLGCGFDTLFWRLVSSGAKL--VKYVEVDFSSVTSKKIRHILKPIGPNSVDLKKSFES-DAVVSHHAD----LHAGNYHLIGADLRQANELDQKLATCQLSHDIPTIFIAECVLVYMSADSSTALLKQIVSQFKQPAFVNYEQFRTSDAFTKVMEQNLGDRGIQLHGLEMCESAEKQEERFRNAGFKEVKVMDMNQIFNNFLDQKEVSRIREIEMLDEMELLQQLFAHYCVVSA 331

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Query:   92 ISNVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFS-----RRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQG-KLDNCTFIELDYFDVAQRK-----AVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVA 1006
            +S+   +Q TND++   K    + GY+ DEF+       S     RR P I+ GY+ R  AIE  +  F+  N+     Q+ SLG GFDT F+RL   G KL    ++E+D+  V  +K       +      L K   S +  VS H D    ++A NY LIG D+ + + LD  +    +S+D+PT+F++ECV+ Y+S   S +LLK I   F +  FV YEQ    D+F + M  +    G  L G++  ++ E Q ER  +AG+      DM + + N +  +E SRI  +E+ DE E       HY V+ A
Sbjct:   25 VSDDYSVQRTNDDATQCKYFATQKGYWKDEFISRFANSSSNVSEARRFPEISMGYWARTAAIEKYVRDFL--NEFDGNAQVVSLGCGFDTLFWRLVSSGAKL--VKYVEVDFSSVTSKKIRHILKPIGPNSVDLKKSFES-DAVVSHHAD----LHAGNYHLIGADLRQANELDQKLATCQLSHDIPTIFIAECVLVYMSADSSTALLKQIVSQFKQPAFVNYEQFRTSDAFTKVMEQNLGDRGIQLHGLEMCESAEKQEERFRNAGFKEVKVMDMNQIFNNFLDQKEVSRIREIEMLDEMELLQQLFAHYCVVSA 331

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Fly
Match: CG3793 (gene:FBgn0028507 transcript:FBtr0080761)

HSP 1 Score: 190.66 bits (483), Expect = 5.791e-54
Identity = 107/303 (35.31%), Postives = 172/303 (56.77%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQG-KLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRG 1015
            +  TND++   K   ++ GY+ D+++ + +    R+AP INRGY+ R K +E  +  F++  K     QI +LG GFDT +FRL     ++ N  FIELD+  V  RK   +++   L   +   +  V L   +   ++  +Y L+G+D+  LD +D+ ++ + V Y LPT+FL+ECV+ YI  +   +LLK+IA+ F    FV YEQ+  +D FG  M ++ +  G SL G+++  + + Q  R   +GW  A +WDM + Y +I S+ E+ RIE LE+ DE E  L    HY ++VA  G
Sbjct:   23 VIATNDDASDCKRCAVRLGYWKDDYIGYFVRNQERKAPEINRGYFARVKGVEMCVEKFLK--KTSGNCQIINLGCGFDTLYFRLRDTAHQVKN--FIELDFPTVTARKCYTIKRNKALLARIHDEDGEVRLSPTD---LHGPSYHLMGVDLRNLDEVDSKLQQAEVDYSLPTIFLAECVLVYIEAQNCRNLLKWIAQKFQAAVFVNYEQVNMNDRFGDVMLNNLRGRGCSLAGVESCLSLDTQRNRFKDSGWTGARAWDMVQVYESI-SAAERQRIERLEMLDEGELLLQLFQHYCLVVAWLG 317

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Fly
Match: CG3793 (gene:FBgn0028507 transcript:FBtr0305560)

HSP 1 Score: 190.66 bits (483), Expect = 6.385e-54
Identity = 107/303 (35.31%), Postives = 172/303 (56.77%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQG-KLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRG 1015
            +  TND++   K   ++ GY+ D+++ + +    R+AP INRGY+ R K +E  +  F++  K     QI +LG GFDT +FRL     ++ N  FIELD+  V  RK   +++   L   +   +  V L   +   ++  +Y L+G+D+  LD +D+ ++ + V Y LPT+FL+ECV+ YI  +   +LLK+IA+ F    FV YEQ+  +D FG  M ++ +  G SL G+++  + + Q  R   +GW  A +WDM + Y +I S+ E+ RIE LE+ DE E  L    HY ++VA  G
Sbjct:   23 VIATNDDASDCKRCAVRLGYWKDDYIGYFVRNQERKAPEINRGYFARVKGVEMCVEKFLK--KTSGNCQIINLGCGFDTLYFRLRDTAHQVKN--FIELDFPTVTARKCYTIKRNKALLARIHDEDGEVRLSPTD---LHGPSYHLMGVDLRNLDEVDSKLQQAEVDYSLPTIFLAECVLVYIEAQNCRNLLKWIAQKFQAAVFVNYEQVNMNDRFGDVMLNNLRGRGCSLAGVESCLSLDTQRNRFKDSGWTGARAWDMVQVYESI-SAAERQRIERLEMLDEGELLLQLFQHYCLVVAWLG 317

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Zebrafish
Match: lcmt2 (leucine carboxyl methyltransferase 2 [Source:ZFIN;Acc:ZDB-GENE-110714-2])

HSP 1 Score: 278.1 bits (710), Expect = 2.302e-82
Identity = 136/305 (44.59%), Postives = 199/305 (65.25%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKD-NYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            +QGTND+S++SK S    GYF+D+FL   + K SRRAPLINRGYY+R KA++H +  F+   K     QI SLGAGFD+ FFRL  +G L   T  E+D+ +VA+RKA L+   + L   L  P+    L+K  N + I++ +Y LIG D+ K   ++A + A+G+ +D PTL LSE V+TY+ T+ S +++ + A+   ++ FV+YEQI+PDD FGR M SHF +L S +  +Q Y     Q +R +  GW+     DM +FY++++  +E+ RIE+LE FDE+EEW  KC+HY +L A +GSV
Sbjct:   15 VQGTNDSSVVSKVSAAAQGYFHDDFLKHFVCKMSRRAPLINRGYYVRWKAVDHCVKQFLHATKSCSRRQILSLGAGFDSLFFRLRAEGALGGVTVFEVDFPEVARRKAALINSNACLKDLL--PDWETVLNKQTNAVFISSGHYNLIGADVRKEQEVEASLSAAGLQWDNPTLILSEVVLTYMETQWSDAVIGWAARLLPQSMFVMYEQIHPDDPFGRVMQSHFLKLNSKIHSLQQYPDNVAQTQRFIQEGWEKCHCLDMNQFYFDLLPEDERQRIENLEPFDEFEEWHQKCSHYFILTASKGSV 317

HSP 2 Score: 77.0258 bits (188), Expect = 4.717e-14
Identity = 78/337 (23.15%), Postives = 129/337 (38.28%), Query Frame = 2

Query: 1415 SLCGSMTRISGNCFIIFGGRSSPLKPN--------DLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXXXXXXCSGSVVSIGTD-----SFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSC-GVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAF-SSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            SL  ++T + G   ++FGGRSSPL P+        DLA  +QL +                                              V     P  RWRH +     +DK +L ++GGRS     L D +        W ++            +VV  G +     S C         G              L P+ + + W  +      +       PR+SH++H++            +  VGGV  +     GV+++++    N+  C+++ +DT S    +M+H+  S     +  ++ ++GGGGNCFSFGT LN +  ++DL  I
Sbjct:  409 SLYQTLTSVPGGGVVLFGGRSSPLSPSGSVVLVTADLADEVQLSFTNI-------------------------------------------VCTGTGPKPRWRHTSTLICYNDKTFLFVFGGRSEKDPILGDAHFLCLEDKHWTEI------------TVVGAGPEARHSHSACPYGGGLVIFGGLGEGGKPLGDALYLRPTSSGFCWEMKDLHPPPV-------PRYSHSAHVINEK---------LVVVGGVWLQADGVPGVSIVNL----NTGSCVEIQLDTLSVPWPLMLHSFCSELLDCEGSELVLIGGGGNCFSFGTHLNLHPVTVDLKPI 670

[Close]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Zebrafish
Match: lcmt2 (leucine carboxyl methyltransferase 2 [Source:ZFIN;Acc:ZDB-GENE-110714-2])

HSP 1 Score: 257.299 bits (656), Expect = 1.186e-74
Identity = 128/292 (43.84%), Postives = 189/292 (64.73%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKD-NYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKC 982
            +QGTND+S++SK S    GYF+D+FL   + K SRRAPLINRGYY+R KAI+H +  F+   K     QI SLGAGFD+ FFRL  +G L   T  E+D+ +VA+RKA L+   + L   L  P+    L+K  N + I++ +Y LIG+D+ K   ++A + A+G+ +D PTL LSE V+TY+ T+ S +++ + A+   ++ F++YEQI PDD FGR M SHF +L S +  +Q Y     Q +R +  GW+     DM +FY++++S +E+ RIE+LE FDE+E+   KC
Sbjct:   15 VQGTNDSSVVSKVSAAAQGYFHDDFLKHFVCKMSRRAPLINRGYYVRWKAIDHCVKQFLHATKSCSRRQILSLGAGFDSLFFRLRAEGALGGVTVFEVDFPEVARRKAALINSNACLKDLL--PDWETVLNKQTNAVFISSGHYNLIGVDVRKEQEVEASLSAAGLQWDNPTLILSEVVLTYMETQWSDAVIGWAARLLPQSMFMMYEQIRPDDPFGRVMQSHFLKLNSKIHSLQQYPDTVAQTQRFIQEGWEKCHCMDMNQFYFDLLSEDERERIENLEPFDEFEKQQQKC 304

HSP 2 Score: 78.5666 bits (192), Expect = 1.843e-14
Identity = 78/336 (23.21%), Postives = 130/336 (38.69%), Query Frame = 2

Query: 1415 SLCGSMTRISGNCFIIFGGRSSPLKPN--------DLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXXXXXXCSGSVVSIGTD-----SFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAF-SSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            SL  ++T + G   ++FGGRSSPL+P+        DLA  +QL +                                              V     P  RWRH +     +DK +L ++GGRS     L D +        W ++            +VV  G +     S C         G              L P+ + + W  +      +       PR+SH++H++      N   V +  V   +   P  GV+++++    N+  C+++ +DT S    +M+H+  S     +  ++ ++GGGGNCFSFGT LN +  ++DL  I
Sbjct:  403 SLYQTLTSVPGGGVVLFGGRSSPLRPSGSVVLVTADLADEVQLSFTNI-------------------------------------------VCTGTGPKPRWRHTSTLICYNDKTFLFVFGGRSEKDPILGDAHFLCLEDKHWTEI------------TVVGAGPEARHSHSACPYGGGLVIFGGLGEGGKPLGDALYLRPTSSGFCWEMKDLHPPPV-------PRYSHSAHVI------NEKLVVVGGVWLQADGVP--GVSIVNL----NTGSCVEIQLDTLSVPWPLMLHSFCSELLDCEGSELVLIGGGGNCFSFGTHLNLHPVTVDLKPI 664

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Zebrafish
Match: lcmt1 (leucine carboxyl methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-040912-75])

HSP 1 Score: 155.606 bits (392), Expect = 1.648e-41
Identity = 95/305 (31.15%), Postives = 167/305 (54.75%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKF-SRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            ++ T D++ + K      GY+ D ++ + + +   R+AP INRGYY R K +  +L  F++  K     Q+ +LGAG DT+F+RL  +  +    F E+D+  +  RK   ++ +  L K L       SL  D +  +++  Y +IG D+  +  L+  ++   ++ +LPTLFLSECV+ Y+S ++S+ L+ +IA++F    F+ YEQ+  +D FG  M  + ++   +L G+   ++ + Q ER L +GW+S  + DM    Y+++  E+ +RIE LE  DE E       HY +  A +  +
Sbjct:   17 VRATCDDASICKRFATSKGYWTDLYVQYFVRQIGERKAPEINRGYYGRVKGMNLLLDDFLK--KTQCDCQVVNLGAGLDTTFWRLKDENIMPK-KFFEVDFPMIVARKIHNIKTKPPLSKPLIETHSTDSLLLDGH-SLDSDRYCIIGADLRDIPTLEDKLKKFQINPELPTLFLSECVLVYMSPEQSSRLVHWIAETFPTAMFINYEQVNMNDRFGHIMIENLQRRQCNLAGVDLCQSLDSQKERFLSSGWESVNALDMMTV-YSMLPQEDVARIERLEFLDEKELLQQLLQHYCICWAVKDKL 316

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Zebrafish
Match: lcmt1 (leucine carboxyl methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-040912-75])

HSP 1 Score: 154.451 bits (389), Expect = 5.028e-41
Identity = 94/305 (30.82%), Postives = 167/305 (54.75%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKF-SRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            ++ T D++ + K      GY+ D ++ + + +   R+AP INRGYY R K +  +L  F++  K     Q+ +LGAG DT+F+RL  +  +    F E+D+  +  RK   ++ +  L K L       SL  D +  +++  Y +IG D+  +  L+  ++   ++ +LPTLFLSECV+ Y+S ++S+ L+ +IA++F    F+ YEQ+  +D FG  M  + ++   +L G+   ++ + Q +R L +GW+S  + DM    Y+++  E+ +RIE LE  DE E       HY +  A +  +
Sbjct:   17 VRATCDDASICKRFATSKGYWTDLYVQYFVRQIGERKAPEINRGYYGRVKGMNLLLDDFLK--KTQCDCQVVNLGAGLDTTFWRLKDENIMPK-KFFEVDFPMIVARKIHNIKTKPPLSKPLIETHSTDSLLLDGH-SLDSDRYCIIGADLRDIPTLEDKLKKFQINPELPTLFLSECVLVYMSPEQSSRLVHWIAETFPTAMFINYEQVNMNDRFGHIMIENLQRRQCNLAGVDLCQSLDSQKDRFLSSGWESVNALDMMTV-YSMLPQEDVARIERLEFLDEKELLQQLLQHYCICWAVKDKL 316

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Zebrafish
Match: lcmt2 (leucine carboxyl methyltransferase 2 [Source:ZFIN;Acc:ZDB-GENE-110714-2])

HSP 1 Score: 124.79 bits (312), Expect = 1.199e-32
Identity = 59/117 (50.43%), Postives = 79/117 (67.52%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKL 460
            +QGTND+S++SK S    GYF+D+FL   + K SRRAPLINRGYY+R KA++H +  F+   K     QI SLGAGFD+ FFRL  +G L   T  E+D+ +VA+RKA L+   + L
Sbjct:   15 VQGTNDSSVVSKVSAAAQGYFHDDFLKHFVCKMSRRAPLINRGYYVRWKAVDHCVKQFLHATKSCSRRQILSLGAGFDSLFFRLRAEGALGGVTVFEVDFPEVARRKAALINSNACL 131

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Xenopus
Match: slco1b3 (solute carrier organic anion transporter family member 1B3 [Source:Xenbase;Acc:XB-GENE-5943217])

HSP 1 Score: 233.417 bits (594), Expect = 1.477e-67
Identity = 125/309 (40.45%), Postives = 184/309 (59.55%), Query Frame = 2

Query:  107 RIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRP 1033
            R+Q TND S LSK S    GYF DE+    + +  RR+PLI+RGY +R++A+ H +  FI + +  D  Q+ SLG GFD+ FFRL  Q +   C + E+D+  V +RK +L++Q   L   L S    V+   +  +V+ +  YKL+G+D+T++  LDA +  +G+S+D PTL L E  + Y+   +S +L+ + A+ F ++ FVLYEQ  P D FGR M SHF  L S L  +  +   + Q +R LH GW +  + DM EF  + V   E  RI +LE FDE+EE  LKC+HY +LVA +G +   P
Sbjct:    6 RVQSTNDCSTLSKVSAASLGYFEDEYQKNFVNRNCRRSPLIHRGYCVRSQAVTHCINEFIRDTQSCDHRQVVSLGCGFDSLFFRLRMQSESPLCVW-EVDFPSVVKRKCLLIEQSGDLRDLLGSY---VTPDDNGPLVLLSQGYKLLGVDLTEVSSLDAALNLAGLSWDCPTLVLGEVALCYMDPARSTALIGWAAERFRDSRFVLYEQSCPSDPFGRVMTSHFASLNSPLLSLSEFPHIQDQEQRFLHKGWKTCRALDMNEFCASCVPLPEVQRIHNLEPFDEFEELHLKCSHYFILVASQGFLAEHP 310

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Query:  107 RIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRP 1033
            R+Q TND S LSK S    GYF DE+    + +  RR+PLI+RGY +R++A+ H +  FI + +  D  Q+ SLG GFD+ FFRL  Q +   C + E+D+  V +RK +L++Q   L   L S    V+   +  +V+ +  YKL+G+D+T++  LDA +  +G+S+D PTL L E  + Y+   +S +L+ + A+ F ++ FVLYEQ  P D FGR M SHF  L S L  +  +   + Q +R LH GW +  + DM EF  + V   E  RI +LE FDE+EE  LKC+HY +LVA +G +   P
Sbjct:    6 RVQSTNDCSTLSKVSAASLGYFEDEYQKNFVNRNCRRSPLIHRGYCVRSQAVTHCINEFIRDTQSCDHRQVVSLGCGFDSLFFRLRMQSESPLCVW-EVDFPSVVKRKCLLIEQSGDLRDLLGSY---VTPDDNGPLVLLSQGYKLLGVDLTEVSSLDAALNLAGLSWDCPTLVLGEVALCYMDPARSTALIGWAAERFRDSRFVLYEQSCPSDPFGRVMTSHFASLNSPLLSLSEFPHIQDQEQRFLHKGWKTCRALDMNEFCASCVPLPEVQRIHNLEPFDEFEELHLKCSHYFILVASQGFLAEHP 310

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Xenopus
Match: slco1b3 (solute carrier organic anion transporter family member 1B3 [Source:Xenbase;Acc:XB-GENE-5943217])

HSP 1 Score: 234.187 bits (596), Expect = 2.297e-65
Identity = 124/308 (40.26%), Postives = 184/308 (59.74%), Query Frame = 2

Query:   92 ISNVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRG 1015
            +S  +++Q TND S LSK S    GYF DE+    + +  RR+PLI+RGY +R++A+ H +  FI + +  D  Q+ SLG GFD+ FFRL  Q +   C + E+D+  V +RK +L++Q   L   L S   P     +  +V+ +  YKL+G+D+T++  LDA +  +G+S+D PTL L E  + Y+   +S +L+ + A+ F ++ FVLYEQ  P D FGR M SHF  L S L  +  +   + Q +R LH GW +  + DM EF  + V   E  RI +LE FDE+EE  LKC+HY +LVA +G
Sbjct:  304 LSVSLQVQSTNDCSTLSKVSAASLGYFEDEYQKNFVNRNCRRSPLIHRGYCVRSQAVTHCINEFIRDTQSCDHRQVVSLGCGFDSLFFRLRMQSESPLCVW-EVDFPSVVKRKCLLIEQSGDLRDLLGSYVTP---DDNGPLVLLSQGYKLLGVDLTEVSSLDAALNLAGLSWDCPTLVLGEVALCYMDPARSTALIGWAAERFRDSRFVLYEQSCPSDPFGRVMTSHFASLNSPLLSLSEFPHIQDQEQRFLHKGWKTCRALDMNEFCASCVPLPEVQRIHNLEPFDEFEELHLKCSHYFILVASQG 607

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Xenopus
Match: lcmt1 (leucine carboxyl methyltransferase 1 [Source:NCBI gene;Acc:548787])

HSP 1 Score: 158.688 bits (400), Expect = 2.407e-42
Identity = 95/305 (31.15%), Postives = 167/305 (54.75%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKF-SRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            ++GT D++ + K   +  GY+ D ++ + + +   R+AP INRGYY R + +  +L  F+   +     QI +LGAG DT+F+RL  +  L    + E+D+  +  RK   ++ +  L K +       SL  D +  ++++ Y +IG D+     ++  ++   +   LPTL ++ECV+ Y++ ++SASLL++   +F+   F+ YEQ+   D FG+ M  + ++   +L G+   ++ E Q ERLL  GW+SA +W+M + Y N+   E+  RIE LE  DE E       HY +  A + S+
Sbjct:   18 VRGTCDDASICKRFAVSAGYWKDPYIQYFVRQAKERKAPEINRGYYARVQGVHLLLKAFLRKTEC--NCQIINLGAGLDTTFWRLKDENLLPK-KYFEVDFPAIVARKLYNIKSKPPLSKPIMETHSGESLLLDAH-SLDSARYSIIGADLRNPKDMEEKLKKMSLDPQLPTLLVTECVLVYMTPEQSASLLQWATNTFTTAMFINYEQVNMMDRFGQIMVENLQRRQCNLAGVDACQSLESQTERLLSTGWESADAWNMMKVYSNL-PQEDVMRIEKLEFLDEKELLEQLLLHYCISWATKDSL 317

[Close]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Xenopus
Match: lcmt1 (leucine carboxyl methyltransferase 1 [Source:NCBI gene;Acc:548787])

HSP 1 Score: 158.303 bits (399), Expect = 3.388e-42
Identity = 95/305 (31.15%), Postives = 167/305 (54.75%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKF-SRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            ++GT D++ + K   +  GY+ D ++ + + +   R+AP INRGYY R + +  +L  F+   +     QI +LGAG DT+F+RL  +  L    + E+D+  +  RK   ++ +  L K +       SL  D +  ++++ Y +IG D+     ++  ++   +   LPTL ++ECV+ Y++ ++SASLL++   +F+   F+ YEQ+   D FG+ M  + ++   +L G+   ++ E Q ERLL  GW+SA +W+M + Y N+   E+  RIE LE  DE E       HY +  A + S+
Sbjct:   18 VRGTCDDASICKRFAVSAGYWKDPYIQYFVRQAKERKAPEINRGYYARVQGVHLLLKAFLRKTEC--NCQIINLGAGLDTTFWRLKDENLLPK-KYFEVDFPAIVARKLYNIKSKPPLSKPIMETHSGESLLLDAH-SLDSARYSIIGADLRNPKDMEEKLKKMSLDPQLPTLLVTECVLVYMTPEQSASLLQWATNTFTTAMFINYEQVNMMDRFGQIMVENLQRRQCNLAGVDACQSLESQTERLLSTGWESADAWNMMKVYSNL-PQEDVMRIEKLEFLDEKELLEQLLLHYCISWATKDSL 317

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Mouse
Match: Lcmt2 (leucine carboxyl methyltransferase 2 [Source:MGI Symbol;Acc:MGI:1353659])

HSP 1 Score: 238.81 bits (608), Expect = 8.086e-68
Identity = 114/308 (37.01%), Postives = 186/308 (60.39%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDA---IQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKD-NYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            +Q TND+S LSK S+  +GY  D F   ++    RR PLI+RGYY+RA+A+ H +  F+E    + +    QI SLG+G D+ +FRL   G L      E+D+ DV++ KA  +++  +L     +   P  +    + +   +++Y+++G D+ +L  L   +  +G+    PTL L+E V+TY+    + +L+ + A+ F +  FV+YEQ+ P D+FG+ M  HF++L S L G++ +   + Q +R L AGW + ++ D+ EFY  ++S+EE+ R+E LE FDEYEEW LKC+HY +L A RG +
Sbjct:   13 VQSTNDSSSLSKRSLAAHGYVRDPFAALLVPGPVRRTPLIHRGYYVRARAVRHCVRAFLELTSALPSRTRAQILSLGSGSDSLYFRLKAAGLLARAAVWEVDFPDVSRLKAERIEETPEL----RAQTGPFKIGDSASSLCFESADYRILGADLRELQRLGEALDGAGLDATSPTLLLAEAVLTYLEPSSATALIAWAAQRFPDALFVIYEQMQPGDAFGQIMLQHFQRLHSPLHGLELFPVVKAQRQRFLQAGWTACSALDLNEFYRRLLSAEERQRVETLEPFDEYEEWHLKCSHYFILAASRGDI 316

HSP 2 Score: 75.8702 bits (185), Expect = 1.312e-13
Identity = 88/321 (27.41%), Postives = 129/321 (40.19%), Query Frame = 2

Query: 1427 SMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXXXXXXCSGSVVSIGTDSFCSNDSPDRXXXXXXXXXXXXXXXXDLVP--SGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGV-SHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            +MTR+S    ++ GGR SP+ P   A +L L+ + D  +   N     A                             A+ E    S  WRH     +  ++ YL +YGGRS     LSD         +W ++  Q         S     + S CS        G          S   L P  SG +W           I    S  PR+SHT+H+             +  VGGV  H +   GVT+I +    +S    +  +DT S    +M+HNH SA   + +Q+ ++GGGGNCFSFGT  N +  ++DLS++
Sbjct:  421 TMTRLSDTRVLVLGGRLSPVSPASGALQLDLYKSKDNCSEGQNVTVTKA-----------------------------ALEEGSVLSC-WRHSTTEVYYQNQRYLFVYGGRSVAEPVLSDCRFLHVETMAWVRIPVQ-------GASPEGRHSHSACSWQGGALIAGGLGASEELLSSVLFLKPVSSGFLWE---------SIDIQPSITPRYSHTAHVF---------NGKLLLVGGVWIHSSSVPGVTVICLTTGLSS----EYQIDTASVPWPLMLHNHSSALLPEEQQLLLIGGGGNCFSFGTYFNPHTVALDLSSL 682

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Mouse
Match: Lcmt1 (leucine carboxyl methyltransferase 1 [Source:MGI Symbol;Acc:MGI:1353593])

HSP 1 Score: 175.637 bits (444), Expect = 2.049e-48
Identity = 100/305 (32.79%), Postives = 179/305 (58.69%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKF-SRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYE--EWLLKCNHYMVLVACRG 1015
            ++GT +++ L K   +  GY++D ++  ++ +   R+AP INRGY+ R   +  ++  F+   +     QI +LGAG DT+F++L  +G L N  + E+D+  +  RK + ++ +  L++ +       +L  D+++ +++  Y +IG D+  L  L+  ++   ++  LPTL ++ECV+ Y++ ++SA+LLK+ A SF    F+ YEQ+  DD FG+ M  + ++    L G++T K+ E Q ERLL  GW++A++ +M E Y  +  + E +RIE LE  DE E  E L++  HY +  A RG
Sbjct:   24 VRGTCEDASLCKRFAVSIGYWHDPYIEHLVRQSKERKAPEINRGYFARVHGVSQLIKAFLRKTEC--HCQILNLGAGMDTTFWKLKDEGLLPN-KYFEVDFPMIVTRKLLTIKSKPLLFRPIMELHPEDTLQMDSHM-LDSKRYAIIGADLRDLSELEEKLKKCNMNTQLPTLLITECVLVYMTPEQSANLLKWAASSFETAMFINYEQVNMDDRFGQIMIENLRRRSCDLAGVETCKSLESQKERLLLNGWETASAVNMMELYSGLPRA-EVNRIESLEFLDEMELLEQLMR--HYCLCWATRG 321

[Close]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Mouse
Match: Lcmt1 (leucine carboxyl methyltransferase 1 [Source:MGI Symbol;Acc:MGI:1353593])

HSP 1 Score: 174.866 bits (442), Expect = 4.382e-48
Identity = 100/305 (32.79%), Postives = 178/305 (58.36%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKF-SRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYE--EWLLKCNHYMVLVACRG 1015
            ++GT +++ L K   +  GY++D ++  ++ +   R+AP INRGY+ R   +  ++  F+   +     QI +LGAG DT+F++L  +G L N  + E+D+  +  RK + ++ +  L++ +       +L   N++ +++  Y +IG D+  L  L+  ++   ++  LPTL ++ECV+ Y++ ++SA+LLK+ A SF    F+ YEQ+  DD FG+ M  + ++    L G++T K+ E Q ERLL  GW++A++ +M E Y  +  + E +RIE LE  DE E  E L++  HY +  A RG
Sbjct:   24 VRGTCEDASLCKRFAVSIGYWHDPYIEHLVRQSKERKAPEINRGYFARVHGVSQLIKAFLRKTEC--HCQILNLGAGMDTTFWKLKDEGLLPN-KYFEVDFPMIVTRKLLTIKSKPLLFRPIMELHPEDTLQMGNHM-LDSKRYAIIGADLRDLSELEEKLKKCNMNTQLPTLLITECVLVYMTPEQSANLLKWAASSFETAMFINYEQVNMDDRFGQIMIENLRRRSCDLAGVETCKSLESQKERLLLNGWETASAVNMMELYSGLPRA-EVNRIESLEFLDEMELLEQLMR--HYCLCWATRG 321

[Close]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Mouse
Match: Lcmt2 (leucine carboxyl methyltransferase 2 [Source:MGI Symbol;Acc:MGI:1353659])

HSP 1 Score: 106.686 bits (265), Expect = 6.956e-24
Identity = 44/96 (45.83%), Postives = 66/96 (68.75%), Query Frame = 2

Query:  734 IYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            + P D+FG+ M  HF++L S L G++ +   + Q +R L AGW + ++ D+ EFY  ++S+EE+ R+E LE FDEYEEW LKC+HY +L A RG +
Sbjct:    1 MQPGDAFGQIMLQHFQRLHSPLHGLELFPVVKAQRQRFLQAGWTACSALDLNEFYRRLLSAEERQRVETLEPFDEYEEWHLKCSHYFILAASRGDI 96

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BLAST of Leucine carboxyl methyltransferase 2 vs. UniProt/SwissProt
Match: sp|O60294|TYW4_HUMAN (tRNA wybutosine-synthesizing protein 4 OS=Homo sapiens OX=9606 GN=LCMT2 PE=1 SV=3)

HSP 1 Score: 259.225 bits (661), Expect = 2.162e-74
Identity = 223/773 (28.85%), Postives = 349/773 (45.15%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAI---QIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSP---EHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRPGPILIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLIQYHSANQQQQTEEPQFKFGGIKTHYVKADLIAGNGTGNRRQYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMRHIEPARSQLLA--------NSLCGSMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXXXXXXCSGSVVSIG-TDSFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGV-SHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            +Q TND+S LSK S+   GY  D F   ++   +RRAPLI+RGYY+RA+A+ H +  F+E      A    QI SLGAGFD+ +FRL   G+L      E+D+ DVA+RKA  + +  +L   L+ P     P S      +   +++Y ++G+D+ +L  ++  + A+G+    PTL L+E V+TY+  + +A+L+ + A+ F    FV+YEQ+ P D+FG+FM  HF+QL S L G++ +   E Q  R L AGW +  + DM EFY+  + +EE+ R+E++E FDE+EEW LKC HY +L A RG         L+            A  S                    + ++    + + P  K  G  + ++  D+I            L + G+G+      HCR++   +L    +     E   SQ+ +          L  +MTR+S +  ++ GGR SP+ P      LQLH+    +    +                                   A  + D     WRH        ++ YL +YGGRS     LSD +       +W              G V     + S C+        G          S   L P       CG    W  +       PR+SHT+H++            +  VGG+  H +   GVT+I++    +S    +  +DT      +M+HNH S    + +Q+ ++GGGGNCFSFGT  N +  ++DLS++
Sbjct:   13 VQNTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWEVDFPDVARRKAERIGETPELC-ALTGPFERGEPASA-----LCFESADYCILGLDLRQLQRVEEALGAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRGDTL---SHTLVFPSSEAFPRVNPASPSGV------------------FPASVVSSEGQVPNLKRYGHASVFLSPDVI------------LSAGGFGEQ--EGRHCRVSQFHLLSRDCDS----EWKGSQIGSCGTGVQWDGRLYHTMTRLSESRVLVLGGRLSPVSPA--LGVLQLHFFKSEDNNTEDLKVTITK----------------------------AGRKDDSTLCCWRHSTTEVSCQNQEYLFVYGGRSVVEPVLSDWHFLHVGTMAW--------VRIPVEGEVPEARHSHSACTWQGGALIAGGLGASEEPLNSVLFLRPIS-----CGF--LWESVDIQPPITPRYSHTAHVL---------NGKLLLVGGIWIHSSSFPGVTVINLTTGLSS----EYQIDTTYVPWPLMLHNHTSILLPEEQQLLLLGGGGNCFSFGTYFNPHTVTLDLSSL 682

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BLAST of Leucine carboxyl methyltransferase 2 vs. UniProt/SwissProt
Match: sp|Q5XIA3|TYW4_RAT (tRNA wybutosine-synthesizing protein 4 OS=Rattus norvegicus OX=10116 GN=Lcmt2 PE=2 SV=1)

HSP 1 Score: 243.817 bits (621), Expect = 9.719e-69
Identity = 114/307 (37.13%), Postives = 189/307 (61.56%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDA---IQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            +Q TND+S LSK S+   GY +D F P ++    RR PLI+RGYY+RA+A+ H +  F++    + +    QI SLG+G D+ +FRL   G L      E+D+ DV++ KA  +++  +L  C  +    +     + +   +S+Y+++G D+ +L  L   + ++G+    PTL L+E V+TY+   ++A+L+ ++A+ F    FV+YEQ+ P D+FG+ M  HF++L S L G++ +   E Q +R L AGW + ++ D+ EFY  ++ ++E+ R+E LE FDE+EEW LKC+HY +L A RG +
Sbjct:   13 VQSTNDSSSLSKRSLAAQGYVSDAFAPLLVPGIVRRTPLIHRGYYVRARAVRHCVRAFLDLTGAIRSPTRAQILSLGSGSDSLYFRLKAAGLLTRTAVWEVDFPDVSRLKAKRIEETPEL--CAQTGPFKIG-DSASTLCFESSDYRILGADLRELQRLGEALDSAGLDATSPTLILAEAVLTYLEPSRAAALIAWVAQRFPNALFVIYEQMKPGDAFGQIMLQHFRRLNSPLHGLELFPDVEAQRQRFLQAGWTTCSALDLNEFYRRLIPADERRRVETLEPFDEFEEWHLKCSHYFILAASRGDI 316

HSP 2 Score: 75.0998 bits (183), Expect = 1.424e-12
Identity = 87/321 (27.10%), Postives = 127/321 (39.56%), Query Frame = 2

Query: 1427 SMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXXXXXXCSGSVVSIGTDSFCSNDSPDRXXXXXXXXXXXXXXXXDLVP--SGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGV-SHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            +MTR+S    ++ GGR SP+ P   A +L ++ + D                                  Q       A+ E    S  WRH     +  ++ YL +YGGRS     LSD         +W ++  Q         S     + S CS        G          S   L P  SG +W           I    S  PR+SHT+H+             +  VGGV  H +   GVT+IS+    +S    +  +DT S    +M+HNH SA   + +Q+ ++GGGGNCFSFGT  N +   +DLS++
Sbjct:  421 TMTRLSDTRVLVLGGRLSPVNPASGALQLDIYKSEDNCPEG-----------------------------QNVVVTKAALEEGSMLSC-WRHSTTEVYYQNQRYLFVYGGRSVTDPVLSDCRFLHVETMAWVRIPVQ-------GSSPEGRHSHSACSWQGGALIAGGLGASEEPLSSVFFLRPVSSGFLWE---------SIHIQPSITPRYSHTAHVF---------NGKLLLVGGVWIHSSSVPGVTVISLTTGLSS----EYQIDTASVPWPLMLHNHSSALLPEEQQLLLIGGGGNCFSFGTYFNPHTVGLDLSSL 682

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BLAST of Leucine carboxyl methyltransferase 2 vs. UniProt/SwissProt
Match: sp|Q8BYR1|TYW4_MOUSE (tRNA wybutosine-synthesizing protein 4 OS=Mus musculus OX=10090 GN=Lcmt2 PE=2 SV=4)

HSP 1 Score: 238.81 bits (608), Expect = 5.656e-67
Identity = 114/308 (37.01%), Postives = 186/308 (60.39%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDA---IQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKD-NYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            +Q TND+S LSK S+  +GY  D F   ++    RR PLI+RGYY+RA+A+ H +  F+E    + +    QI SLG+G D+ +FRL   G L      E+D+ DV++ KA  +++  +L     +   P  +    + +   +++Y+++G D+ +L  L   +  +G+    PTL L+E V+TY+    + +L+ + A+ F +  FV+YEQ+ P D+FG+ M  HF++L S L G++ +   + Q +R L AGW + ++ D+ EFY  ++S+EE+ R+E LE FDEYEEW LKC+HY +L A RG +
Sbjct:   13 VQSTNDSSSLSKRSLAAHGYVRDPFAALLVPGPVRRTPLIHRGYYVRARAVRHCVRAFLELTSALPSRTRAQILSLGSGSDSLYFRLKAAGLLARAAVWEVDFPDVSRLKAERIEETPEL----RAQTGPFKIGDSASSLCFESADYRILGADLRELQRLGEALDGAGLDATSPTLLLAEAVLTYLEPSSATALIAWAAQRFPDALFVIYEQMQPGDAFGQIMLQHFQRLHSPLHGLELFPVVKAQRQRFLQAGWTACSALDLNEFYRRLLSAEERQRVETLEPFDEYEEWHLKCSHYFILAASRGDI 316

HSP 2 Score: 75.8702 bits (185), Expect = 9.178e-13
Identity = 88/321 (27.41%), Postives = 129/321 (40.19%), Query Frame = 2

Query: 1427 SMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXXXXXXCSGSVVSIGTDSFCSNDSPDRXXXXXXXXXXXXXXXXDLVP--SGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGV-SHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            +MTR+S    ++ GGR SP+ P   A +L L+ + D  +   N     A                             A+ E    S  WRH     +  ++ YL +YGGRS     LSD         +W ++  Q         S     + S CS        G          S   L P  SG +W           I    S  PR+SHT+H+             +  VGGV  H +   GVT+I +    +S    +  +DT S    +M+HNH SA   + +Q+ ++GGGGNCFSFGT  N +  ++DLS++
Sbjct:  421 TMTRLSDTRVLVLGGRLSPVSPASGALQLDLYKSKDNCSEGQNVTVTKA-----------------------------ALEEGSVLSC-WRHSTTEVYYQNQRYLFVYGGRSVAEPVLSDCRFLHVETMAWVRIPVQ-------GASPEGRHSHSACSWQGGALIAGGLGASEELLSSVLFLKPVSSGFLWE---------SIDIQPSITPRYSHTAHVF---------NGKLLLVGGVWIHSSSVPGVTVICLTTGLSS----EYQIDTASVPWPLMLHNHSSALLPEEQQLLLIGGGGNCFSFGTYFNPHTVALDLSSL 682

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BLAST of Leucine carboxyl methyltransferase 2 vs. UniProt/SwissProt
Match: sp|Q8VY08|LCMT1_ARATH (Leucine carboxyl methyltransferase 1 homolog OS=Arabidopsis thaliana OX=3702 GN=LCMT1 PE=1 SV=1)

HSP 1 Score: 201.445 bits (511), Expect = 6.383e-57
Identity = 110/309 (35.60%), Postives = 175/309 (56.63%), Query Frame = 2

Query:   95 SNVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            SN   +Q TND++  SK S +K GY  D+++   + +  RR+P+INRGY+ R  A   ++  F+ +       QI SLGAGFDT++F+L  +G   N  ++ELD+ +V  +KA ++Q  S+L   L +     S+  D   V+ + +YKL+ +D+  +  L   I  + +   LPT  ++ECV+ Y+    S +++ + +K+FS   F LYEQI+PDD+FG  M  + +  G +L  I    T   +    L  GW  A +WDM + Y + V ++EK RIE LE+FDE+EEW +   HY V  A   ++
Sbjct:    6 SNRAAVQATNDDASASKLSCVKKGYMKDDYVHLFVKRPVRRSPIINRGYFSRWAAFRKLMSQFLLSGTSSKK-QILSLGAGFDTTYFQLLDEGNGPNL-YVELDFKEVTSKKAAVIQNSSQLRDKLGAN---ASISIDEGQVL-SDHYKLLPVDLRDIPKLRDVISFADMDLSLPTFIIAECVLIYLDPDSSRAIVNWSSKTFSTAVFFLYEQIHPDDAFGHQMIRNLESRGCALLSIDASPTLLAKERLFLDNGWQRAVAWDMLKVYGSFVDTQEKRRIERLELFDEFEEWHMMQEHYCVTYAVNDAM 308

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BLAST of Leucine carboxyl methyltransferase 2 vs. UniProt/SwissProt
Match: sp|Q6P4Z6|LCMT1_RAT (Leucine carboxyl methyltransferase 1 OS=Rattus norvegicus OX=10116 GN=Lcmt1 PE=2 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 2.245e-46
Identity = 99/305 (32.46%), Postives = 179/305 (58.69%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKF-SRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYE--EWLLKCNHYMVLVACRG 1015
            ++GT +++ L K   +  G+++D ++  ++ +   R+AP INRGY+ R   +  ++  F+   +     QI +LGAG DT+F++L  +G L N  + E+D+  +  RK   ++ +  L++ +       +L  D+++ +++  Y +IG D+  L  L+  ++   ++  LPTL ++ECV+ Y++ ++SA+LLK+ A+SF    F+ YEQ+  DD FG+ M  + ++    L G++T K+ E Q ERLL  GW++A++ +M E Y  +  + E +RIE LE  DE E  E L++  HY +  A RG
Sbjct:   24 VRGTCEDASLCKRFAVSIGHWHDPYIEHLVRQSKERKAPEINRGYFARVHGVSQLIKAFLRKTEC--RCQILNLGAGMDTTFWKLKDEGLLPN-KYFEVDFPMIVTRKLHTIKNKPLLFRPIMELHPEDTLQIDSHM-LDSKRYAIIGADLRDLSELEEKLKKCNMNTQLPTLLITECVLVYMTPEQSANLLKWAARSFETAMFINYEQVNMDDRFGQIMIENLRRRQCDLAGVETCKSLESQKERLLLNGWETASAVNMMELYSGLPRA-EVNRIESLEFLDEMELLEQLMR--HYCLCWATRG 321

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BLAST of Leucine carboxyl methyltransferase 2 vs. TrEMBL
Match: H2ZX29 (Leucine carboxyl methyltransferase 2 OS=Latimeria chalumnae OX=7897 GN=LCMT2 PE=4 SV=1)

HSP 1 Score: 359.762 bits (922), Expect = 1.474e-109
Identity = 247/781 (31.63%), Postives = 377/781 (48.27%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFI-ENNKHMDA---IQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRPGPILIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLIQYHSANQQQQTEEPQFKFGGIKTHYVKADLIAGNGTGNRRQYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMRH----IEPARSQLLANSLCGSMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEA----DKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIF---DFS-----LNSWXXXXXXXXXXXXCSGSVVSIGTDSFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQ--QWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGV-SHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNID 2383
            +QGTND+SI+SKCSM+K  YF D+FL + + K SRRAPLINRGYYIRAKA++H    F+ +   H      IQI SLGAGFD+S+FRL   G L N    E+D+ DV  RKA L+  E +L + + S    +   +   + ++ ++Y+L+G+D+++L+ LD  +  +G++   PTL LSE V+TY+   +S++++++ ++ F+   FV+YEQI P D FG+ M  HFKQL S+L  +  Y  +E Q +R L  GW+ +T  DM EFY+  +  EE+ R+E LE FDE+EEW LKC+HY +L A +G +                             +             + + S        E   K  G++ +  ++ LI  N        ++ + G+G+   +  H RL  L +   +  +  H    +E    QL    +  SMT IS +  +I GGR SPL P+     L+    +D +                                   CS  ++V E        S RWRH A      D+ YL IYGG S     L+D Y     DFS     +  +           L +G+VV  G         P+                   +P G+I+          W E+ ++ S +PR+SHT+HIV            +  VGGV  H     GVT+I +     + +C+D  ++T      +M+HNH S    + KQ++++GGGGNCFSFGT LN++   + L+++D
Sbjct:   11 VQGTNDSSIVSKCSMVKLDYFKDDFLKYFVKKSSRRAPLINRGYYIRAKAVDHCFKQFLMQTGGHPQIGIFIQILSLGAGFDSSYFRLKAGGLLKNVIMYEVDFPDVVSRKAALITNEKELAELVGSAGE-IRPAESGIVCLSGTDYRLLGVDLSELEKLDEGLIGAGLNLTCPTLILSEVVLTYMDNARSSAVIQWASEHFASAVFVIYEQIRPADPFGQVMQKHFKQLNSTLHALVEYPDREAQKKRFLDLGWEESTCVDMNEFYFGFIPKEERKRLETLEPFDEFEEWHLKCSHYFILTAFKGEL--------------------------KICSMLNAPTGSLLTKSVPFSSKTISASPCEVDSKVSGLRRYGHRSCLIKSN-------VVITTGGFGEQ--AGQHGRLKDLQLSVKSGAIWEHGPVTVEDTE-QLWDARIFHSMTPISDDQCVIVGGRLSPLNPSTNILCLKCRQKSDFD----------------------------------SCSVNVSVQEVCVDMKSLSPRWRHSATGMKYKDQSYLFIYGGCSPTDKVLNDWYFLNLEDFSRTEILVEGFVPEGRHSHSACLWNGAVVIAG------GLGPEE------------------MPLGSIYLLIPTTTGFTWQEVEASPSVIPRYSHTAHIVDDK---------LLLVGGVLIHSDTIPGVTVIDL----KTGQCVDYQINTAHLEWPLMLHNHSSVLMEEEKQLFVIGGGGNCFSFGTHLNQHPVLLSLASVD 683

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BLAST of Leucine carboxyl methyltransferase 2 vs. TrEMBL
Match: H2ZX30 (Leucine carboxyl methyltransferase 2 OS=Latimeria chalumnae OX=7897 GN=LCMT2 PE=4 SV=1)

HSP 1 Score: 359.762 bits (922), Expect = 1.665e-109
Identity = 245/784 (31.25%), Postives = 375/784 (47.83%), Query Frame = 2

Query:   86 KEISNVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRPGPILIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLIQYHSANQQQQTEEPQFKFGGIKTHYVKADLIAGNGTGNRRQYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMRH----IEPARSQLLANSLCGSMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEA----DKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIF---DFS-----LNSWXXXXXXXXXXXXCSGSVVSIGTDSFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQ--QWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGV-SHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            K +     +QGTND+SI+SKCSM+K  YF D+FL + + K SRRAPLINRGYYIRAKA++H    F+         QI SLGAGFD+S+FRL   G L N    E+D+ DV  RKA L+  E +L + + S    +   +   + ++ ++Y+L+G+D+++L+ LD  +  +G++   PTL LSE V+TY+   +S++++++ ++ F+   FV+YEQI P D FG+ M  HFKQL S+L  +  Y  +E Q +R L  GW+ +T  DM EFY+  +  EE+ R+E LE FDE+EEW LKC+HY +L A +G +                             +             + + S        E   K  G++ +  ++ LI  N        ++ + G+G+   +  H RL  L +   +  +  H    +E    QL    +  SMT IS +  +I GGR SPL P+     L+    +D +                                   CS  ++V E        S RWRH A      D+ YL IYGG S     L+D Y     DFS     +  +           L +G+VV  G         P+                   +P G+I+          W E+ ++ S +PR+SHT+HIV            +  VGGV  H     GVT+I +     + +C+D  ++T      +M+HNH S    + KQ++++GGGGNCFSFGT LN++   + L+++
Sbjct:   13 KRVGKDSAVQGTNDSSIVSKCSMVKLDYFKDDFLKYFVKKSSRRAPLINRGYYIRAKAVDHCFKQFLMQTGGHPQRQILSLGAGFDSSYFRLKAGGLLKNVIMYEVDFPDVVSRKAALITNEKELAELVGSAGE-IRPAESGIVCLSGTDYRLLGVDLSELEKLDEGLIGAGLNLTCPTLILSEVVLTYMDNARSSAVIQWASEHFASAVFVIYEQIRPADPFGQVMQKHFKQLNSTLHALVEYPDREAQKKRFLDLGWEESTCVDMNEFYFGFIPKEERKRLETLEPFDEFEEWHLKCSHYFILTAFKGEL--------------------------KICSMLNAPTGSLLTKSVPFSSKTISASPCEVDSKVSGLRRYGHRSCLIKSN-------VVITTGGFGEQ--AGQHGRLKDLQLSVKSGAIWEHGPVTVEDTE-QLWDARIFHSMTPISDDQCVIVGGRLSPLNPSTNILCLKCRQKSDFD----------------------------------SCSVNVSVQEVCVDMKSLSPRWRHSATGMKYKDQSYLFIYGGCSPTDKVLNDWYFLNLEDFSRTEILVEGFVPEGRHSHSACLWNGAVVIAG------GLGPEE------------------MPLGSIYLLIPTTTGFTWQEVEASPSVIPRYSHTAHIVDDK---------LLLVGGVLIHSDTIPGVTVIDL----KTGQCVDYQINTAHLEWPLMLHNHSSVLMEEEKQLFVIGGGGNCFSFGTHLNQHPVLLSLASV 688

[Close]

BLAST of Leucine carboxyl methyltransferase 2 vs. TrEMBL
Match: A0A401PCW1 (Uncharacterized protein OS=Scyliorhinus torazame OX=75743 GN=scyTo_0008734 PE=4 SV=1)

HSP 1 Score: 311.612 bits (797), Expect = 3.208e-91
Identity = 242/780 (31.03%), Postives = 363/780 (46.54%), Query Frame = 2

Query:   86 KEISNVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINR-----GYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEH--PVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVC---WRPGPILIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLIQYHSANQQQQTEEPQF-KFGGIKTHYVKADLIAGNGTGNRRQYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMR---HIEPARSQLLANSLCGSMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXXXXXXCSGSVVSIGTDSFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSCG-VTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            K+    + +QGTND+SI+SKCSM+  GYFND FL   + K +RRAPLINR       Y+        L   I  +     +QI SLGAGFD+ +FRL   G+L N    E+D+ +V QRKA L++ + +  + +   +   P  + +   + +++ +YKL+G+D+T++  LD  +  +G++   PTL LSE V+TY+  + S++++ + A  F    FV+YEQI PDD FG+ M  HF QL S+L  +  +  KE Q +R L+ GW+     DM EFY   +  +EK RIE LE FDEYEEW LKC+HY++L A +G +      P P                              ++  LN ++   +  + +TE P   +F    +H     ++   G G+R          GQ      H RL  +S++     V +     +     LL   +  SMT +     IIFGGR+SPLKP  + + L L+                       D +       G ++ + ECS        D P  RWRH A         YL IYGGRS     L+D +  +    SW  +            +  S  + S CS        G          S   L P+     W G    W  I +  SF+PR+SHT+HI+            +  +GGV+ ++ S   VTLI +     + +  D  +D+   +  +M+HNH S    + +Q+ ++GGGGNCFSFGT LN     + L  I
Sbjct:   22 KQTGKDVAVQGTNDSSIVSKCSMVNLGYFNDVFLKGFVNKTTRRAPLINRIILVLNIYVLTANENSPLKCNIAASYAFSFLQILSLGAGFDSLYFRLKASGELKNVVVYEVDFPNVVQRKATLIKNKQEFVELIGCIDEIRPTQMGR---LYLSSMDYKLLGMDLTEIVELDHLLMQTGLNPACPTLILSEVVLTYMKGESSSAVIHWAADRFPSAIFVVYEQIRPDDPFGQVMQRHFTQLNSTLYALTQFPGKEAQRKRFLNEGWEECHCIDMNEFYVGFIPEQEKQRIELLEPFDEYEEWHLKCSHYLILSASKGFLTCLFLHPPP-------------------------DFHFKKIDTLNPLRITVSLCETETENPLLRRFAHCSSHIAPNIILISGGFGSRD---------GQ------HGRLKDVSLMFKNGPVWKCSSFGDQGSIHLLTERMFHSMTALCDKRCIIFGGRTSPLKP--VTSLLCLN----------------------CDMSDGAISSIGLSVKEIECS-------GDVPLPRWRHSATEVIYKGLKYLFIYGGRSPRELVLNDWHFLNLEDYSWADIPVN-------GPTPESRHSHSACSWKGGVLIAGGLGAARIPLASIFHLRPT-----WSGF--IWDRIETVSSFIPRYSHTAHIIGDK---------LLLLGGVTIQSDSIPEVTLIDL----KTGQSFDQCIDSNLVTWPLMLHNHSSVLVKE-RQVLVIGGGGNCFSFGTHLNHQPILLKLPEI 699

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BLAST of Leucine carboxyl methyltransferase 2 vs. TrEMBL
Match: A0A2G8JUX9 (Putative tRNA wybutosine-synthesizing protein 4 OS=Stichopus japonicus OX=307972 GN=BSL78_23597 PE=4 SV=1)

HSP 1 Score: 291.967 bits (746), Expect = 2.599e-84
Identity = 180/475 (37.89%), Postives = 262/475 (55.16%), Query Frame = 2

Query:   98 NVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSP----EHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRPGPILIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLIQYHSANQQQQTEEPQFKFGGIKTHYVKADLIAGNGTGNRR---QYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMRHIEPAR-SQLLANSLCGSMTRISGN--CFIIFGGRSSPLKP 1492
            N   +QGTND+SI+SKC++   GYF+D++L   + + +RRAPLINRGYY+RAKAI+  L  F+++ +   A QI SLGAGFD++FFRL     L    F E+D+ +VA RKA ++Q    L   L  P    ++PV + KD  ++I++S+Y+L+GI++  L  L   +  SG   + PTL LSECV+TY+  ++S +L++F A +FS   F+ YEQIYP DSFGR M +HFK+LGS L+ I+ Y T     ER L  GW SA   DM EFY   +  EE+ RI+ LE FDE+EEW LKCNHY+++ AC+GS                              A   D  R    +   Y    Q  Q  E Q      + ++      +G G  + R     +L   G+G       H RL+ +  +++ T     +EP   S ++   +  ++T ++ N    +IFGGR+SP KP
Sbjct:    9 NETAVQGTNDSSIVSKCAITMQGYFHDDYLRHFVARQTRRAPLINRGYYVRAKAIDGALRHFLKSFQ-GQANQIVSLGAGFDSAFFRLESARLLSETCFYEIDFAEVACRKAAIIQSNDILCALLKEPVFHHKNPV-VQKDGGVIISSSSYQLLGINLNDLSSLHRFLLHSGCDLNKPTLLLSECVLTYMEVQRSDALIEFCANTFSNAAFICYEQIYPSDSFGRVMMNHFKKLGSPLQAIRMYSTPSDHQERYLRLGWTSAKVIDMNEFYL-CLHEEERDRIKKLEPFDEFEEWHLKCNHYILVTACKGSC---------------------------ITAFQDDIHRSNSGSFRMYQQKPQLDQLLEAQLPDSITEANF------SGFGHSSERISSTTVLVHGGFGDK--GGRHQRLSEMVAMNIHTGNSFTVEPEEGSDVIGPRMFHTITALNHNKSSLLIFGGRTSPTKP 445

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BLAST of Leucine carboxyl methyltransferase 2 vs. TrEMBL
Match: A0A2G8JEX5 (Putative tRNA wybutosine-synthesizing protein 4 OS=Stichopus japonicus OX=307972 GN=BSL78_28880 PE=4 SV=1)

HSP 1 Score: 290.812 bits (743), Expect = 8.648e-84
Identity = 176/472 (37.29%), Postives = 258/472 (54.66%), Query Frame = 2

Query:   98 NVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSP----EHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRPGPILIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLIQYHSANQQQQTEEPQFKFGGIKTHYVKADLIAGNGTGNRRQYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMRHIEPAR-SQLLANSLCGSMTRISGN--CFIIFGGRSSPLKP 1492
            N   +QGTND+SI+SKC++   GYF+D++L   + + +RRAPLINRGYY+RAKAI+  L  F+++ +   A QI SLGAGFD++FFRL     L    F E+D+ +VA RKA ++Q    L   L  P    ++PV + KD  ++I++S+Y+L+GI++  L  L   +  SG   + PTL LSECV+TY+  ++S +L++F A +FS   F+ YEQIYP DSFGR M +HFK+LGS L+ I+ Y T     ER L  GW SA   DM EFY   +  +E+ RI+ LE FDE+EEW LKCNHY+++ AC+GS                     A           +  +      L Q   A       E  F   G  +  + +  +  +G            G+G       H RL+ L  +++ T     +EP   S ++   +  ++T ++ N    +IFGGR+SP KP
Sbjct:    9 NETAVQGTNDSSIVSKCAISMQGYFHDDYLRHFVARQTRRAPLINRGYYVRAKAIDGALRHFLKSFQ-GQANQIVSLGAGFDSAFFRLESARLLSETCFYEIDFAEVANRKAAIIQSNDILCALLKEPVFHHKNPV-VQKDGGVIISSSSYRLLGINLNDLSSLHRFLLHSGCDLNKPTLLLSECVLTYMEVQRSDALIEFCASTFSNVAFICYEQIYPSDSFGRVMMNHFKKLGSPLQAIRMYSTPSDHQERYLRLGWTSAKVIDMNEFYL-CLGEDERDRIKKLEPFDEFEEWHLKCNHYILVTACKGSC------------------ITAFQDDIHRSNSGSFRMYQQKPRLDQLLEAQLPDSITEANFSGFGHSSERISSTTVLVHG------------GFGDK--GGRHQRLSELVAMNVHTGNSFTVEPEEGSDVIGPRMFHTITALNHNKSSLLIFGGRTSPTKP 445

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Cavefish
Match: lcmt2 (leucine carboxyl methyltransferase 2 [Source:NCBI gene;Acc:103040183])

HSP 1 Score: 275.018 bits (702), Expect = 4.092e-81
Identity = 128/304 (42.11%), Postives = 196/304 (64.47%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            +QGTND+S++SK S    GYF D+ L   + K SRRAPLINRGYY+R +A++H +  F+   ++    QI SLGAGFD+ +FRLH +G L+     E+D+ DV +RKA L++   +L   L    H   L     + ++++ YKL+G+D+     ++  +R +G+ +D PTL LSE V+TY+ TK S +++ + A+S S+  FV+YEQI PDD FGR M +HF +L S +  +  Y     Q +R L  GW+  T  DM +FY++++S +E+ R+E++E FDE+EEW  KC+HY +L A +GS+
Sbjct:   24 VQGTNDSSVVSKVSAAAQGYFQDDLLQHFVCKVSRRAPLINRGYYVRWQAVDHCVKGFLRVTENCAGRQILSLGAGFDSLYFRLHAEGALERVVVFEVDFPDVTRRKAALIKGNDRLKDALPDWNH---LEPTGPVCVSSAQYKLLGVDVRTEREVEEGLRVAGLQWDRPTLVLSEVVLTYMETKWSDAVIGWAARSLSQALFVMYEQIRPDDPFGRVMQNHFLKLNSKIHALCQYPDTSAQTKRFLQQGWEKCTCLDMNQFYFSLLSQDEQERVENMEPFDEFEEWHQKCSHYFILSASKGSL 324

HSP 2 Score: 77.7962 bits (190), Expect = 2.641e-14
Identity = 77/339 (22.71%), Postives = 129/339 (38.05%), Query Frame = 2

Query: 1427 SMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXX--------XXXXCS--GSVVSIGT---------DSFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSC-GVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAF-SSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            ++T + G   ++ GGR+SPL P D   ++  H +   ++                                     ++   +A KP  RWRH A       K YL ++GGR+     L D +        W                    C+  G VV  G          D    NDSP                      +G +W+         ++    + +PR+SH++H++  +         +  VGGV  +     GV +I++   +N    I++ +DT S    +M+H+  S    SD  ++ ++GGGGNCFSFGT LN +  ++DL  +
Sbjct:  419 TLTSVPGWGAVVTGGRTSPLNPIDSVLKVTHHLSDQPDSRTVLL----------------------------SVEKMVCTGQAPKP--RWRHTATLLNHKGKNYLFVFGGRTEKEPVLGDAHFLCLEDQHWTDARVPLEGCFPEPRHSHSACAYRGGVVIFGGLGRGGVPLGDVMWLNDSP----------------------TGFVWK---------KVQLRPALVPRYSHSAHVIGEN---------LVVVGGVWLQADGVPGVAVINLTTGSN----IEVTIDTSSVPWPLMLHSFCSELLDSDRTEVVLIGGGGNCFSFGTHLNIHPVTLDLRPV 683

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Cavefish
Match: lcmt2 (leucine carboxyl methyltransferase 2 [Source:NCBI gene;Acc:103040183])

HSP 1 Score: 275.018 bits (702), Expect = 4.149e-81
Identity = 128/304 (42.11%), Postives = 196/304 (64.47%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            +QGTND+S++SK S    GYF D+ L   + K SRRAPLINRGYY+R +A++H +  F+   ++    QI SLGAGFD+ +FRLH +G L+     E+D+ DV +RKA L++   +L   L    H   L     + ++++ YKL+G+D+     ++  +R +G+ +D PTL LSE V+TY+ TK S +++ + A+S S+  FV+YEQI PDD FGR M +HF +L S +  +  Y     Q +R L  GW+  T  DM +FY++++S +E+ R+E++E FDE+EEW  KC+HY +L A +GS+
Sbjct:   28 VQGTNDSSVVSKVSAAAQGYFQDDLLQHFVCKVSRRAPLINRGYYVRWQAVDHCVKGFLRVTENCAGRQILSLGAGFDSLYFRLHAEGALERVVVFEVDFPDVTRRKAALIKGNDRLKDALPDWNH---LEPTGPVCVSSAQYKLLGVDVRTEREVEEGLRVAGLQWDRPTLVLSEVVLTYMETKWSDAVIGWAARSLSQALFVMYEQIRPDDPFGRVMQNHFLKLNSKIHALCQYPDTSAQTKRFLQQGWEKCTCLDMNQFYFSLLSQDEQERVENMEPFDEFEEWHQKCSHYFILSASKGSL 328

HSP 2 Score: 77.7962 bits (190), Expect = 2.499e-14
Identity = 77/339 (22.71%), Postives = 129/339 (38.05%), Query Frame = 2

Query: 1427 SMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXX--------XXXXCS--GSVVSIGT---------DSFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSC-GVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAF-SSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNI 2380
            ++T + G   ++ GGR+SPL P D   ++  H +   ++                                     ++   +A KP  RWRH A       K YL ++GGR+     L D +        W                    C+  G VV  G          D    NDSP                      +G +W+         ++    + +PR+SH++H++  +         +  VGGV  +     GV +I++   +N    I++ +DT S    +M+H+  S    SD  ++ ++GGGGNCFSFGT LN +  ++DL  +
Sbjct:  423 TLTSVPGWGAVVTGGRTSPLNPIDSVLKVTHHLSDQPDSRTVLL----------------------------SVEKMVCTGQAPKP--RWRHTATLLNHKGKNYLFVFGGRTEKEPVLGDAHFLCLEDQHWTDARVPLEGCFPEPRHSHSACAYRGGVVIFGGLGRGGVPLGDVMWLNDSP----------------------TGFVWK---------KVQLRPALVPRYSHSAHVIGEN---------LVVVGGVWLQADGVPGVAVINLTTGSN----IEVTIDTSSVPWPLMLHSFCSELLDSDRTEVVLIGGGGNCFSFGTHLNIHPVTLDLRPV 687

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Sea Lamprey
Match: lcmt1 (leucine carboxyl methyltransferase 1 [Source:ZFIN;Acc:ZDB-GENE-040912-75])

HSP 1 Score: 103.219 bits (256), Expect = 4.650e-25
Identity = 56/209 (26.79%), Postives = 110/209 (52.63%), Query Frame = 2

Query:  392 FIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGS 1018
            + ELD+  +  RK  +++ ++ L K +       SL  D    +N+  + ++G+D+  L  +   +R +G+   LPT+ ++ECV+ Y++ + S+ L+++ A +F    F+ YEQ+  +D FG+ M  + +    SL G+   ++ + QM R    GW+ A + +M    YN +   ++ R+E +E  DE E       HY ++ A + +
Sbjct:   18 YFELDFPAITSRKIHIIKTKAPLSKAVLETHSSDSLALDGA-NLNSDRFAILGVDLRDLATVQQKLRDTGLDPQLPTVLVAECVLVYMTLEHSSRLVRWAADTFPTALFINYEQVNMEDRFGQVMIENLQHRQCSLAGVTACRSLQTQMARFSDNGWEKADALNMMTV-YNCLPHTDRRRMEKIEFLDEGELLQQLLQHYGLIWAVKDA 224

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001847.1 (pep scaffold:Pmarinus_7.0:GL480510:776:12411:1 gene:ENSPMAG00000001681.1 transcript:ENSPMAT00000001847.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.1738 bits (178), Expect = 3.836e-14
Identity = 72/263 (27.38%), Postives = 105/263 (39.92%), Query Frame = 2

Query: 1646 CSPLIAVNEAD----KPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXXX-XXXCSGSVVSIGTDSFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQQ----WTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDS------------KQIYIVGGGGNCFSFGTQLNENVYSIDL 2371
             +P +A++E       PS RWRH A       + +L +YGGR +    LSD +  D    +W QL    S      S +    G  +  +                    G+ LVP G +       Q     W ++       PR+SHT+H++          V +  VG  S   P+  +    IDL+  S +  +  VDT      V++H H +    DS            + I+IVGGGGNCFSFGT LN     + L
Sbjct:   98 AAPSLALSEVPCIGAAPSPRWRHAACVVSCRGRRFLFVYGGRDTQHLVLSDWHFLDLEAFTWTQLPVSGSRPEGRHSHAACGFGEGAVVAGG-----------------LGAALVPLGCVHLLSPAAQHEGFTWRQLPLRHPITPRYSHTAHVIEERR-----LVLVGGVGIHSAYPPALAI----IDLLTGSTQ--EYNVDTCGVEGPVLLHGHSAVERWDSGGGCGGDGKDHERHIFIVGGGGNCFSFGTHLNPRPLILRL 332

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Yeast
Match: PPM2 (AdoMet-dependent tRNA methyltransferase; also involved in methoxycarbonylation; required for the synthesis of wybutosine (yW), a modified guanosine found at the 3'-position adjacent to the anticodon of phe-tRNA; similarity to Ppm1p [Source:SGD;Acc:S000005501])

HSP 1 Score: 112.464 bits (280), Expect = 5.009e-26
Identity = 95/327 (29.05%), Postives = 158/327 (48.32%), Query Frame = 2

Query:  104 IRIQGTNDNSILSKCS-----MIKYGYFND----------EFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRL------HKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYD--LPTLFLSECVITYISTKKSASLLKFIAKSFSENC-FVLYEQIYPDDSFGRF---MCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEV--FDEYEEWLLKCNHYMV 997
            + IQGTN++SI SK S     + K    N+          E+  F + K  +R+P INRGY++R  AI   L + IE       I + +LG G+D   F+L        Q   D  +FI++DY D+ + K  L++   +L K +   E    +   N   +    Y     D+    +    +    + YD  +  +F++E  + Y+  ++S S+++  A S  EN  F++ EQ+ P   F  F   M +HFK+  S L+ +  Y T E Q++R    G+      DM + +    S++E ++ E L+V  FDE EE+ L C+HY++
Sbjct:   25 LAIQGTNNSSIASKRSVELLYLPKLSSANNFQMDKNNKLLEYFKFFVPKKIKRSPCINRGYWLRLFAIRSRLNSIIEQTPQDKKIVVVNLGCGYDPLPFQLLDTNNIQSQQYHDRVSFIDIDYSDLLKIKIELIKTIPELSKIIGLSEDKDYVDDSNVDFLTTPKYLARPCDLNDSKMFSTLLNECQL-YDPNVVKVFVAEVSLAYMKPERSDSIIE--ATSKMENSHFIILEQLIPKGPFEPFSKQMLAHFKRNDSPLQSVLKYNTIESQVQRFNKLGFAYVNVGDMFQLWE---SADEATKKELLKVEPFDELEEFHLFCHHYVL 345

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Yeast
Match: PPM1 (Carboxyl methyltransferase; methylates the C terminus of the protein phosphatase 2A catalytic subunit (Pph21p or Pph22p), which is important for complex formation with regulatory subunits; required for methionine to inhibit autophagy and promote growth [Source:SGD;Acc:S000002843])

HSP 1 Score: 94.7449 bits (234), Expect = 1.664e-21
Identity = 77/306 (25.16%), Postives = 142/306 (46.41%), Query Frame = 2

Query:  158 KYGYFNDEFLPFMIGKFSRRA------------PLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLD----ILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQI---YPDDSFGRFMCSHFKQLGS-SLRGIQTYKTKEMQMERLLHAGWDSATSW---DMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVA 1006
            KY  ++  +L   + KFSRRA            P++N G Y+R   I+  +L F+  N   + +Q+ +LG G D     L +     +  ++++DY +  + K  ++++   L   L   +   +    +  +I+   YKL   D+  +     +LD C +      ++PT+ +SEC++ Y+   +S  L+  I   FS   ++ Y+ I    P+D FG  M S+ K+  +  +  + TY +KE    R     W +A +    DM E +   +   E+ R+  L+  DE EE  +   HY+++ A
Sbjct:   40 KYTEWHRSYL-ITLKKFSRRAFGKVDKAMRSSFPVMNYGTYLRTVGIDAAILEFLVAN---EKVQVVNLGCGSDLRMLPLLQM--FPHLAYVDIDYNESVELKNSILRESEILRISLGLSKEDTA---KSPFLIDQGRYKLAACDLNDITETTRLLDVCTKR-----EIPTIVISECLLCYMHNNESQLLINTIMSKFSHGLWISYDPIGGSQPNDRFGAIMQSNLKESRNLEMPTLMTYNSKEKYASR-----WSAAPNVIVNDMWEIFNAQIPESERKRLRSLQFLDELEELKVMQTHYILMKA 326

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BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Nematostella
Match: EDO42453 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1F7])

HSP 1 Score: 256.144 bits (653), Expect = 8.105e-75
Identity = 130/305 (42.62%), Postives = 190/305 (62.30%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNK--HMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGS 1018
            +Q TND+SILSK SM++ GYF DEFL F + K ++R+PLINRGYYIR KA+  +L  F+E++   +   +QI SLGAGFDTSFFR   +G+L N  F E+D+ +V + K   ++Q + L+      E P   H ++Y         L+G D+  L  L+  +   G+    PTL LSE V++Y+    S++++ + AK F    FV YEQ+YP+D FG  M +HF +LGS LR I +Y + + Q++R +  GW  A   DM  F+ N+   EEK R+E +E FDE+EEW LKC+HY+++   +GS
Sbjct:    1 VQSTNDSSILSKFSMVRAGYFKDEFLKFFVTKDAKRSPLINRGYYIRIKAVSQVLSLFLESSFKCYSHYLQILSLGAGFDTSFFRFASEGRLTNTRFFEVDFPEVVKHKIKFIKQ-NNLFNIPHENELPSGFHSEDY--------SLLGCDLKNLQGLEQKLLGCGIDTSCPTLLLSEVVLSYLDPISSSAVICWAAKRFDSAVFVSYEQVYPEDPFGVVMINHFNRLGSPLRSITSYPSPQAQVQRYIEKGWTKAQYQDMNSFFNNL-PVEEKQRVEAIEPFDEFEEWHLKCSHYILICGLKGS 295

HSP 2 Score: 65.855 bits (159), Expect = 4.018e-11
Identity = 42/121 (34.71%), Postives = 66/121 (54.55%), Query Frame = 2

Query: 2006 RRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSID 2368
            ++ +  +I  N    PR+SHT+H+  RS        ++  +GGVS KT  C    + ++LV+ + + +   V   S    VM+HNH S       +I ++GGGGNCFSFGT LN+N   ++
Sbjct:  543 QKFEVQDIDINPPLPPRYSHTAHL--RSE-------SLILIGGVSQKTTGCPSATV-LNLVSMTWKLLAFPVSPSSSP--VMLHNHCSV-DIGFDRIMVLGGGGNCFSFGTHLNQNALVLN 650

[Close]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Nematostella
Match: EDO32727 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SU99])

HSP 1 Score: 139.813 bits (351), Expect = 2.255e-37
Identity = 77/222 (34.68%), Postives = 125/222 (56.31%), Query Frame = 2

Query:  116 GTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFK 781
             TND++   K S ++ GY+ D F+ + + +  RR P INRGYY R K +  ++  F+E      + QI SLGAGFDT F++L  +GK D   F+E+D+  V  RK   ++   +L K + + E  +++  +    +++ +Y LI  D+  L  LD      G+  DLPTLFL ECV  Y+  + SA+L+ +  ++F+   F+ +EQ+   D FG+ M  + K
Sbjct:   11 ATNDDASSCKRSAVQKGYWEDNFIQYFVKQAERRTPEINRGYYARVKGMHTLVEQFVELTDR--SCQIISLGAGFDTLFWQLKHKGK-DPAVFVEVDFSSVTSRKCHSIKMRKQL-KEVFTAEDNLTIDPNE---VHSKSYHLIAADLRDLSALDTKFTEIGLDRDLPTLFLVECVFVYMKPEHSAALIDWTGRNFNTAIFINFEQVNMQDRFGQVMIENLK 225

[Close]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Medaka
Match: lcmt1 (leucine carboxyl methyltransferase 1 [Source:NCBI gene;Acc:101171444])

HSP 1 Score: 153.68 bits (387), Expect = 6.940e-41
Identity = 92/305 (30.16%), Postives = 166/305 (54.43%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKF-SRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            ++ T D++ + K      GY+ D ++ + +     R+AP INRGYY R + +  +L  F++  K     QI +LGAG DT+F+RL K   L    F E+D+  +  RK   ++ +  L K +       SL  D +  +++  Y +IG D+  +  ++  ++   ++ +LPTL L+ECV+ Y++  +S+ L++++A++F    F+ YEQ    D FG+ M  + ++    L G++T ++ ++Q ER L +GW+ A++ DM    Y+++  E+  RIE LE  DE E       HY +  A +  +
Sbjct:   17 VRATCDDATVCKRFATSKGYWKDPYIQYFVRSVGERKAPEINRGYYARVQGVNFLLDAFLK--KTQCNCQIINLGAGLDTTFWRL-KDNNLMPRKFFEVDFPTIVSRKIHYIKTKPPLSKPIIETHSTDSLLLDAH-SLDSDRYCIIGADLRNISDMEEKLKKFQLNTELPTLVLTECVLVYMTPSQSSGLIRWVAETFHSAMFINYEQANMCDRFGQVMIENLQRRQCMLAGVETCQSLDLQKERFLRSGWEHASALDMITV-YSMLPQEDVGRIERLEFLDEGELLQQLLQHYSISWATKDKL 316

[Close]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Medaka
Match: lcmt1 (leucine carboxyl methyltransferase 1 [Source:NCBI gene;Acc:101171444])

HSP 1 Score: 153.295 bits (386), Expect = 1.319e-40
Identity = 92/305 (30.16%), Postives = 166/305 (54.43%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKF-SRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSV 1021
            ++ T D++ + K      GY+ D ++ + +     R+AP INRGYY R + +  +L  F++  K     QI +LGAG DT+F+RL K   L    F E+D+  +  RK   ++ +  L K +       SL  D +  +++  Y +IG D+  +  ++  ++   ++ +LPTL L+ECV+ Y++  +S+ L++++A++F    F+ YEQ    D FG+ M  + ++    L G++T ++ ++Q ER L +GW+ A++ DM    Y+++  E+  RIE LE  DE E       HY +  A +  +
Sbjct:   17 VRATCDDATVCKRFATSKGYWKDPYIQYFVRSVGERKAPEINRGYYARVQGVNFLLDAFLK--KTQCNCQIINLGAGLDTTFWRL-KDNNLMPRKFFEVDFPTIVSRKIHYIKTKPPLSKPIIETHSTDSLLLDAH-SLDSDRYCIIGADLRNISDMEEKLKKFQLNTELPTLVLTECVLVYMTPSQSSGLIRWVAETFHSAMFINYEQANMCDRFGQVMIENLQRRQCMLAGVETCQSLDLQKERFLRSGWEHASALDMITV-YSMLPQEDVGRIERLEFLDEGELLQQLLQHYSISWATKDKL 316

[Close]

BLAST of Leucine carboxyl methyltransferase 2 vs. Planmine SMEST
Match: SMESG000049235.1 (SMESG000049235.1)

HSP 1 Score: 1372.84 bits (3552), Expect = 0.000e+0
Identity = 776/776 (100.00%), Postives = 776/776 (100.00%), Query Frame = 2

Query:   65 MXXXXXXKEISNVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRPGPILIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNLIQYHSANQQQQTEEPQFKFGGIKTHYVKADLIAGNGTGNRRQYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMRHIEPARSQLLANSLCGSMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWXXXXXXXXXXXXCSGSVVSIGTDSFCSNDSPDRXXXXXXXXXXXXXXXXDLVPSGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNIDFYK 2392
            MNSNNNNKEISNVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRPGPILIDVPVTLAAAAAAAPVSPADPADPADTLRLPPLNLIQYHSANQQQQTEEPQFKFGGIKTHYVKADLIAGNGTGNRRQYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMRHIEPARSQLLANSLCGSMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYNADANAADGNAADGNAADGNAADANADNGGGGGGNLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWQQLLGQQSPGPLCSGSVVSIGTDSFCSNDSPDRCCGCCCLLLTGGLSGSDLVPSGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNIDFYK
Sbjct:    1 MNSNNNNKEISNVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGSVCWRPGPILIDVPVTLAAAAAAAPVSPADPADPADTLRLPPLNLIQYHSANQQQQTEEPQFKFGGIKTHYVKADLIAGNGTGNRRQYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMRHIEPARSQLLANSLCGSMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYNADANAADGNAADGNAADGNAADANADNGGGGGGNLWQAECSPLIAVNEADKPSARWRHMAGCYWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWQQLLGQQSPGPLCSGSVVSIGTDSFCSNDSPDRCCGCCCLLLTGGLSGSDLVPSGNIWRWCGRRQQWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSCGVTLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGGGNCFSFGTQLNENVYSIDLSNIDFYK 776

[Close]

BLAST of Leucine carboxyl methyltransferase 2 vs. Planmine SMEST
Match: SMESG000027726.1 (SMESG000027726.1)

HSP 1 Score: 130.954 bits (328), Expect = 3.643e-33
Identity = 92/304 (30.26%), Postives = 155/304 (50.99%), Query Frame = 2

Query:  110 IQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSRRAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLHKQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNYIVINASNYKLIGIDM-TKLDILDACIRASGVSYDLPTLFLSECVITYISTKKSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQTYKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYEEWLLKCNHYMVLVACRGS 1018
            IQ T+++++ +K S +K GY+ D ++ F I +   +AP INRGY+ R ++IE I   FI +N   ++ QI ++G+G DT + RL  Q  L    F+E+D  +   +K     Q  K++K   +      L +  Y       Y L   D+ +  + L   ++   +++  PTLF++ECV+ YI+++     L  +A  F  + F+ Y+ I   DSFG+ M S+ K     L GI    +KE  + R   A +     W ++E Y +  S +   RIE +E+ D+ E      +HY ++VA   S
Sbjct:    9 IQDTDNDAVEAKASAVKLGYWKDPYIKFFINEPKNKAPEINRGYFARTQSIEAITKEFIMSN---NSSQIINVGSGSDTLYLRLLDQDVLP-FKFVEIDLTENIMKKVSQFHQR-KIFKEKFNLNQQSKLSESIY----NHPYYLFSFDIRSDPNELIEILKKVEINFANPTLFITECVLVYINSESVDKFLSSMANHFQLSVFLSYDPINMLDSFGKVMVSNLKMRHIELNGISACMSKETHIHRFNKAYYSDVKVWLISEVYKSF-SKQTTKRIESIEMLDDPEMMKQLFDHYCLIVAMTKS 302

The following BLAST results are available for this feature:

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Human
BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Celegans
BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Fly
BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Zebrafish
BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Xenopus
BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Mouse
BLAST of Leucine carboxyl methyltransferase 2 vs. UniProt/SwissProt
BLAST of Leucine carboxyl methyltransferase 2 vs. TrEMBL
BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Cavefish
BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Sea Lamprey
BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Yeast
BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Nematostella
BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Medaka
BLAST of Leucine carboxyl methyltransferase 2 vs. Planmine SMEST

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
LCMT2	4.502e-75	28.85	leucine carboxyl methyltransferase 2 [Source:HGNC ...	[more]
LCMT1	3.852e-45	33.87	leucine carboxyl methyltransferase 1 [Source:HGNC ...	[more]
LCMT1	2.139e-24	42.45	leucine carboxyl methyltransferase 1 [Source:HGNC ...	[more]
LCMT1	7.709e-17	30.72	leucine carboxyl methyltransferase 1 [Source:HGNC ...	[more]
LCMT1	6.940e-13	40.00	leucine carboxyl methyltransferase 1 [Source:HGNC ...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
lcmt-1	1.543e-41	33.54	Leucine carboxyl methyltransferase 1 [Source:UniP...	[more]
lcmt-1	1.543e-41	33.54	Leucine carboxyl methyltransferase 1 [Source:UniP...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2


Match Name	E-value	Identity	Description
CG3793	5.791e-54	35.31	gene:FBgn0028507 transcript:FBtr0080761	[more]
CG3793	6.385e-54	35.31	gene:FBgn0028507 transcript:FBtr0305560	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lcmt2	2.302e-82	44.59	leucine carboxyl methyltransferase 2 [Source:ZFIN;...	[more]
lcmt2	1.186e-74	43.84	leucine carboxyl methyltransferase 2 [Source:ZFIN;...	[more]
lcmt1	1.648e-41	31.15	leucine carboxyl methyltransferase 1 [Source:ZFIN;...	[more]
lcmt1	5.028e-41	30.82	leucine carboxyl methyltransferase 1 [Source:ZFIN;...	[more]
lcmt2	1.199e-32	50.43	leucine carboxyl methyltransferase 2 [Source:ZFIN;...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
slco1b3	1.477e-67	40.45	solute carrier organic anion transporter family me...	[more]
slco1b3	1.477e-67	40.45	solute carrier organic anion transporter family me...	[more]
slco1b3	2.297e-65	40.26	solute carrier organic anion transporter family me...	[more]
lcmt1	2.407e-42	31.15	leucine carboxyl methyltransferase 1 [Source:NCBI ...	[more]
lcmt1	3.388e-42	31.15	leucine carboxyl methyltransferase 1 [Source:NCBI ...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Lcmt2	8.086e-68	37.01	leucine carboxyl methyltransferase 2 [Source:MGI S...	[more]
Lcmt1	2.049e-48	32.79	leucine carboxyl methyltransferase 1 [Source:MGI S...	[more]
Lcmt1	4.382e-48	32.79	leucine carboxyl methyltransferase 1 [Source:MGI S...	[more]
Lcmt2	6.956e-24	45.83	leucine carboxyl methyltransferase 2 [Source:MGI S...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O60294\|TYW4_HUMAN	2.162e-74	28.85	tRNA wybutosine-synthesizing protein 4 OS=Homo sap...	[more]
sp\|Q5XIA3\|TYW4_RAT	9.719e-69	37.13	tRNA wybutosine-synthesizing protein 4 OS=Rattus n...	[more]
sp\|Q8BYR1\|TYW4_MOUSE	5.656e-67	37.01	tRNA wybutosine-synthesizing protein 4 OS=Mus musc...	[more]
sp\|Q8VY08\|LCMT1_ARATH	6.383e-57	35.60	Leucine carboxyl methyltransferase 1 homolog OS=Ar...	[more]
sp\|Q6P4Z6\|LCMT1_RAT	2.245e-46	32.46	Leucine carboxyl methyltransferase 1 OS=Rattus nor...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
H2ZX29	1.474e-109	31.63	Leucine carboxyl methyltransferase 2 OS=Latimeria ...	[more]
H2ZX30	1.665e-109	31.25	Leucine carboxyl methyltransferase 2 OS=Latimeria ...	[more]
A0A401PCW1	3.208e-91	31.03	Uncharacterized protein OS=Scyliorhinus torazame O...	[more]
A0A2G8JUX9	2.599e-84	37.89	Putative tRNA wybutosine-synthesizing protein 4 OS...	[more]
A0A2G8JEX5	8.648e-84	37.29	Putative tRNA wybutosine-synthesizing protein 4 OS...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
lcmt2	4.092e-81	42.11	leucine carboxyl methyltransferase 2 [Source:NCBI ...	[more]
lcmt2	4.149e-81	42.11	leucine carboxyl methyltransferase 2 [Source:NCBI ...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
lcmt1	4.650e-25	26.79	leucine carboxyl methyltransferase 1 [Source:ZFIN;...	[more]
ENSPMAT00000001847.1	3.836e-14	27.38	pep scaffold:Pmarinus_7.0:GL480510:776:12411:1 gen...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
PPM2	5.009e-26	29.05	AdoMet-dependent tRNA methyltransferase; also invo...	[more]
PPM1	1.664e-21	25.16	Carboxyl methyltransferase; methylates the C termi...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO42453	8.105e-75	42.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32727	2.255e-37	34.68	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
lcmt1	6.940e-41	30.16	leucine carboxyl methyltransferase 1 [Source:NCBI ...	[more]
lcmt1	1.319e-40	30.16	leucine carboxyl methyltransferase 1 [Source:NCBI ...	[more]

BLAST of Leucine carboxyl methyltransferase 2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000049235.1	0.000e+0	100.00	SMESG000049235.1	[more]
SMESG000027726.1	3.643e-33	30.26	SMESG000027726.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30026423 ID=SMED30026423|Name=Leucine carboxyl methyltransferase 2|organism=Schmidtea mediterranea sexual|type=transcript|length=2417bp
GTCTCTACATTTACAATTAATTAATTATATTAAGCTATTAGATTTTTAGG
GGTTATATCTAATAATGAATAGCAACAATAATAATAAAGAAATTTCTAAT
GTTATAAGAATTCAAGGTACCAATGATAATAGTATTCTTAGTAAGTGCTC
TATGATAAAATATGGATACTTTAATGATGAATTTTTACCATTCATGATTG
GTAAATTTTCTAGACGAGCTCCACTTATTAATAGAGGATATTATATTCGT
GCCAAAGCTATTGAACACATTCTATTGACCTTTATTGAAAATAATAAGCA
CATGGATGCTATTCAAATATTCTCACTAGGCGCCGGATTCGATACATCAT
TTTTTCGTTTACATAAACAAGGAAAATTGGACAATTGTACATTTATAGAG
TTAGATTATTTCGATGTAGCTCAACGTAAAGCGGTATTAATGCAACAGGA
ATCGAAGCTCTGGAAATGCCTATCAAGCCCTGAACATCCAGTTTCATTGC
ATAAGGATAATTACATTGTGATAAATGCTTCTAATTATAAGCTAATCGGA
ATCGACATGACGAAACTGGATATATTGGACGCGTGCATCCGTGCCTCAGG
CGTGTCATACGACCTGCCGACCCTCTTCCTCTCGGAATGCGTCATAACAT
ACATCAGCACCAAGAAATCGGCAAGTTTGCTGAAATTTATTGCCAAATCA
TTTAGTGAGAATTGCTTCGTGTTGTATGAGCAGATCTATCCGGACGACAG
CTTTGGCAGATTCATGTGCTCCCATTTCAAGCAGTTGGGCTCGTCCCTGA
GAGGAATACAGACCTATAAAACAAAGGAGATGCAGATGGAGAGGTTGCTG
CACGCGGGCTGGGATTCCGCGACCAGCTGGGACATGGCAGAATTCTACTA
CAACATCGTCAGTTCCGAGGAGAAATCTCGCATCGAGCATCTGGAGGTGT
TTGATGAGTACGAGGAGTGGCTGCTGAAATGCAATCATTACATGGTGCTG
GTTGCGTGCAGAGGCAGTGTGTGTTGGAGGCCCGGCCCAATCCTGATTGA
TGTCCCGGTCACCCTTGCTGCTGCTGCTGCTGCTGCCCCTGTTAGCCCCG
CTGATCCCGCTGATCCCGCTGACACCCTGCGGTTACCCCCACTGAATCTC
ATCCAATATCATTCCGCCAATCAGCAGCAGCAGACAGAGGAACCCCAGTT
CAAATTCGGCGGCATCAAAACCCATTATGTGAAGGCTGATCTGATCGCTG
GCAACGGAACCGGGAACCGGCGGCAGTACCTGTTGCGGAGCTCTGGATAC
GGACAGAACCCGTTCAGTGCCGGCCATTGTCGATTGACTTGTCTCAGTAT
TCTCGATCTCACCACGAATGTCATGAGGCACATCGAGCCGGCCCGGTCGC
AGCTGCTCGCCAACTCTCTGTGCGGCAGCATGACGCGGATCTCGGGCAAC
TGCTTCATCATATTCGGTGGCAGATCATCACCGTTGAAACCGAATGATCT
GGCTACGAGATTGCAGTTGCATTACAATGCTGATGCCAATGCCGCTGATG
GCAATGCCGCTGATGGCAATGCCGCTGATGGCAATGCCGCTGATGCCAAT
GCTGATAATGGCGGCGGCGGCGGCGGCAATTTATGGCAGGCAGAATGCTC
ACCATTAATTGCCGTTAATGAAGCCGATAAACCATCTGCCCGATGGCGTC
ACATGGCCGGTTGCTATTGGTTACATGACAAACCATATCTGCTTATTTAC
GGCGGCAGAAGCAGTGATCCAAATCCGTTATCGGATAATTATATATTTGA
CTTTTCTCTGAATTCCTGGCAACAGTTGCTAGGGCAACAAAGTCCTGGTC
CGTTATGCAGTGGCTCCGTGGTTTCTATAGGCACTGATTCGTTCTGTAGC
AACGATTCACCTGACCGGTGCTGCGGTTGCTGTTGCCTGTTGCTAACTGG
CGGTCTCTCCGGTAGCGATTTGGTGCCCTCGGGTAACATCTGGCGCTGGT
GTGGCCGGCGGCAACAGTGGACCGAGATTGCTAGCAACCGATCCTTTCTG
CCGAGGTTCTCACATACGTCCCACATTGTCTATCGGTCCAATCATTGCAA
TCCCACAACGGTTACCATGGCATCTGTTGGAGGCGTTTCTCACAAGACCC
CGAGTTGCGGTGTGACCTTGATCTCAATCGATCTGGTTGCCAACAGCGCT
CGGTGCATTGATATGGCTGTGGATACGGGCAGCCAATCAGAATGCGTTAT
GATACACAATCACGGTAGCGCGTTTTCATCGGATTCCAAGCAAATATATA
TAGTCGGAGGCGGTGGAAACTGTTTCAGCTTTGGTACCCAGCTGAATGAG
AATGTTTACTCTATTGATTTGTCAAACATTGATTTTTATAAATAAATTTT
TGATTTTTCTAAAAAAA

protein sequence of SMED30026423-orf-1

>SMED30026423-orf-1 ID=SMED30026423-orf-1|Name=SMED30026423-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=777bp
MNSNNNNKEISNVIRIQGTNDNSILSKCSMIKYGYFNDEFLPFMIGKFSR
RAPLINRGYYIRAKAIEHILLTFIENNKHMDAIQIFSLGAGFDTSFFRLH
KQGKLDNCTFIELDYFDVAQRKAVLMQQESKLWKCLSSPEHPVSLHKDNY
IVINASNYKLIGIDMTKLDILDACIRASGVSYDLPTLFLSECVITYISTK
KSASLLKFIAKSFSENCFVLYEQIYPDDSFGRFMCSHFKQLGSSLRGIQT
YKTKEMQMERLLHAGWDSATSWDMAEFYYNIVSSEEKSRIEHLEVFDEYE
EWLLKCNHYMVLVACRGSVCWRPGPILIDVPVTLAAAAAAAPVSPADPAD
PADTLRLPPLNLIQYHSANQQQQTEEPQFKFGGIKTHYVKADLIAGNGTG
NRRQYLLRSSGYGQNPFSAGHCRLTCLSILDLTTNVMRHIEPARSQLLAN
SLCGSMTRISGNCFIIFGGRSSPLKPNDLATRLQLHYNADANAADGNAAD
GNAADGNAADANADNGGGGGGNLWQAECSPLIAVNEADKPSARWRHMAGC
YWLHDKPYLLIYGGRSSDPNPLSDNYIFDFSLNSWQQLLGQQSPGPLCSG
SVVSIGTDSFCSNDSPDRCCGCCCLLLTGGLSGSDLVPSGNIWRWCGRRQ
QWTEIASNRSFLPRFSHTSHIVYRSNHCNPTTVTMASVGGVSHKTPSCGV
TLISIDLVANSARCIDMAVDTGSQSECVMIHNHGSAFSSDSKQIYIVGGG
GNCFSFGTQLNENVYSIDLSNIDFYK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR007213	Ppm1/Ppm2/Tcmp
IPR029063	SAM-dependent_MTases
IPR015915	Kelch-typ_b-propeller

Vocabulary: **molecular function**
Term	Definition
GO:0008168	methyltransferase activity
GO:0005515	protein binding

Vocabulary: **biological process**
Term	Definition
GO:0032259	methylation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	GENE3D	G3DSA:3.40.50.150		coord: 1..321 e-value: 5.5E-101 score: 340.1
None	No IPR available	PFAM	PF13418	Kelch_4	coord: 543..594 e-value: 2.7E-5 score: 24.1
None	No IPR available	PANTHER	PTHR46529	FAMILY NOT NAMED	coord: 4..771
IPR007213	Methyltransferase Ppm1/Ppm2/Tcmp	PFAM	PF04072	LCM	coord: 49..210 e-value: 1.5E-21 score: 77.2
IPR015915	Kelch-type beta propeller	GENE3D	G3DSA:2.120.10.80		coord: 624..771 e-value: 3.3E-11 score: 44.8
IPR015915	Kelch-type beta propeller	SUPERFAMILY	SSF117281	Kelch motif	coord: 424..766
IPR029063	S-adenosyl-L-methionine-dependent methyltransferase	SUPERFAMILY	SSF53335	S-adenosyl-L-methionine-dependent methyltransferases	coord: 16..316