Kunitz-type serine protease inhibitor BmKTT-2

Overview


Name	Kunitz-type serine protease inhibitor BmKTT-2
Smed ID	SMED30026393
Length (bp)	419

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Kunitz-type serine protease inhibitor BmKTT-2 (SMED30026393) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Kunitz-type serine protease inhibitor BmKTT-2 (SMED30026393) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30026393

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
prepharyngeal region	SMED30026393	SmedASXL_018636	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
pigment cell	SMED30026393	SmedASXL_018636	SmedAsxl_ww_GCZZ01	PMID:29158443 He et al., 2017
gut	SMED30026393	dd_Smed_v4_71_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
tail region	SMED30026393	dd_Smed_v6_71_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
body wall musculature	SMED30026393	dd_Smed_v4_71_0_1	dd_Smed_v4	PMID:30471994 Scimone et al., 2018
goblet cell	SMED30026393	dd_Smed_v6_71_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Human
Match: WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30916])

HSP 1 Score: 69.707 bits (169), Expect = 2.623e-14
Identity = 27/51 (52.94%), Postives = 35/51 (68.63%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+ P   G C AY PR+ +N Q+G C+SF+YGGC+ NGNNF + E CE  C
Sbjct:  293 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 343

HSP 2 Score: 46.9802 bits (110), Expect = 2.271e-6
Identity = 20/55 (36.36%), Postives = 30/55 (54.55%), Query Frame = 3

Query:  159 APECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            A EC +P  +  C     R++F+ Q+ NC +F +G C  N N+F T E C   C+
Sbjct:  232 AAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACM 286

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Human
Match: WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30916])

HSP 1 Score: 69.707 bits (169), Expect = 3.632e-14
Identity = 27/51 (52.94%), Postives = 35/51 (68.63%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+ P   G C AY PR+ +N Q+G C+SF+YGGC+ NGNNF + E CE  C
Sbjct:  386 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436

HSP 2 Score: 46.595 bits (109), Expect = 3.032e-6
Identity = 20/55 (36.36%), Postives = 30/55 (54.55%), Query Frame = 3

Query:  159 APECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            A EC +P  +  C     R++F+ Q+ NC +F +G C  N N+F T E C   C+
Sbjct:  325 AAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACM 379

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Human
Match: APLP2 (amyloid beta precursor like protein 2 [Source:HGNC Symbol;Acc:HGNC:598])

HSP 1 Score: 61.2326 bits (147), Expect = 3.235e-11
Identity = 24/51 (47.06%), Postives = 31/51 (60.78%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C++   TG C A  PR+YF++  G C  FIYGGC  N NNF + + C A C
Sbjct:  310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Human
Match: APLP2 (amyloid beta precursor like protein 2 [Source:HGNC Symbol;Acc:HGNC:598])

HSP 1 Score: 61.2326 bits (147), Expect = 3.240e-11
Identity = 24/51 (47.06%), Postives = 31/51 (60.78%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C++   TG C A  PR+YF++  G C  FIYGGC  N NNF + + C A C
Sbjct:  320 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 370

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Human
Match: APLP2 (amyloid beta precursor like protein 2 [Source:HGNC Symbol;Acc:HGNC:598])

HSP 1 Score: 61.2326 bits (147), Expect = 3.241e-11
Identity = 24/51 (47.06%), Postives = 31/51 (60.78%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C++   TG C A  PR+YF++  G C  FIYGGC  N NNF + + C A C
Sbjct:  310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 65.0846 bits (157), Expect = 6.346e-13
Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 3

Query:  153 SRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +RA  C+ PK+ G C  Y  RFYFN     C+ F +GGC+ N NNF  +E+CE+ C
Sbjct:  534 ARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 2 Score: 61.2326 bits (147), Expect = 1.151e-11
Identity = 24/52 (46.15%), Postives = 30/52 (57.69%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C  P   G+C  Y PR++FN Q+G CE F YG C  N NNF     CE +C+
Sbjct: 2177 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKCM 2228

HSP 3 Score: 60.077 bits (144), Expect = 3.560e-11
Identity = 24/51 (47.06%), Postives = 32/51 (62.75%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C  P+ +G C   F R++F+ +  NC+ F Y GCQ NGNNF + EEC A C
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 787

HSP 4 Score: 58.151 bits (139), Expect = 1.285e-10
Identity = 24/63 (38.10%), Postives = 34/63 (53.97%), Query Frame = 3

Query:  135 IFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            + ++ +S    C    + G CA  F RF F+     C SF YGGC  N NNF T++EC  +C+
Sbjct:  855 VMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCV 917

HSP 5 Score: 57.7658 bits (138), Expect = 2.184e-10
Identity = 23/52 (44.23%), Postives = 31/52 (59.62%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +C +P + G C  +  R+YFN+  G C  F YGGC  N N+F T +ECE  C
Sbjct: 1082 KCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1133

HSP 6 Score: 55.4546 bits (132), Expect = 1.338e-9
Identity = 26/64 (40.62%), Postives = 33/64 (51.56%), Query Frame = 3

Query:  138 FSLGESRA---PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +S+  SR     EC      G C   F R+++N  S  CE F Y GC  NGNN+ + E CE RC
Sbjct:  410 YSIQSSRTVNTKECVGVSLPGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 7 Score: 51.6026 bits (122), Expect = 3.089e-8
Identity = 21/65 (32.31%), Postives = 36/65 (55.38%), Query Frame = 3

Query:  162 PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQTFEISKI 356
            P C +P   G C     R+Y++  + +C  F Y GC  N NNF ++E+C+  C+  +Q+ +  K+
Sbjct: 2740 PLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCVLNIQSIKNGKV 2804

HSP 8 Score: 45.4394 bits (106), Expect = 3.553e-6
Identity = 19/51 (37.25%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+  K +G    Y  ++YFN+++  CE F++ G   N N F T+ ECE  C
Sbjct: 2241 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERIC 2291

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 64.6994 bits (156), Expect = 7.057e-13
Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 3

Query:  153 SRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +RA  C+ PK+ G C  Y  RFYFN     C+ F +GGC+ N NNF  +E+CE+ C
Sbjct:  534 ARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 2 Score: 61.2326 bits (147), Expect = 1.267e-11
Identity = 24/52 (46.15%), Postives = 30/52 (57.69%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C  P   G+C  Y PR++FN Q+G CE F YG C  N NNF     CE +C+
Sbjct: 2168 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKCM 2219

HSP 3 Score: 59.6918 bits (143), Expect = 3.920e-11
Identity = 24/51 (47.06%), Postives = 32/51 (62.75%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C  P+ +G C   F R++F+ +  NC+ F Y GCQ NGNNF + EEC A C
Sbjct:  728 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 778

HSP 4 Score: 58.151 bits (139), Expect = 1.388e-10
Identity = 24/63 (38.10%), Postives = 34/63 (53.97%), Query Frame = 3

Query:  135 IFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            + ++ +S    C    + G CA  F RF F+     C SF YGGC  N NNF T++EC  +C+
Sbjct:  846 VMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCV 908

HSP 5 Score: 57.3806 bits (137), Expect = 2.405e-10
Identity = 23/52 (44.23%), Postives = 31/52 (59.62%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +C +P + G C  +  R+YFN+  G C  F YGGC  N N+F T +ECE  C
Sbjct: 1073 KCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1124

HSP 6 Score: 55.0694 bits (131), Expect = 1.531e-9
Identity = 26/64 (40.62%), Postives = 33/64 (51.56%), Query Frame = 3

Query:  138 FSLGESRA---PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +S+  SR     EC      G C   F R+++N  S  CE F Y GC  NGNN+ + E CE RC
Sbjct:  410 YSIQSSRTVNTKECVGVSLPGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 7 Score: 51.2174 bits (121), Expect = 3.304e-8
Identity = 21/65 (32.31%), Postives = 36/65 (55.38%), Query Frame = 3

Query:  162 PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQTFEISKI 356
            P C +P   G C     R+Y++  + +C  F Y GC  N NNF ++E+C+  C+  +Q+ +  K+
Sbjct: 2731 PLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCVLNIQSIKNGKV 2795

HSP 8 Score: 45.4394 bits (106), Expect = 3.836e-6
Identity = 19/51 (37.25%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+  K +G    Y  ++YFN+++  CE F++ G   N N F T+ ECE  C
Sbjct: 2232 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERIC 2282

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 64.6994 bits (156), Expect = 7.328e-13
Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 3

Query:  153 SRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +RA  C+ PK+ G C  Y  RFYFN     C+ F +GGC+ N NNF  +E+CE+ C
Sbjct:  405 ARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 460

HSP 2 Score: 61.2326 bits (147), Expect = 1.316e-11
Identity = 24/52 (46.15%), Postives = 30/52 (57.69%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C  P   G+C  Y PR++FN Q+G CE F YG C  N NNF     CE +C+
Sbjct: 2048 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKCM 2099

HSP 3 Score: 59.6918 bits (143), Expect = 4.071e-11
Identity = 24/51 (47.06%), Postives = 32/51 (62.75%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C  P+ +G C   F R++F+ +  NC+ F Y GCQ NGNNF + EEC A C
Sbjct:  608 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 658

HSP 4 Score: 58.151 bits (139), Expect = 1.483e-10
Identity = 24/63 (38.10%), Postives = 34/63 (53.97%), Query Frame = 3

Query:  135 IFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            + ++ +S    C    + G CA  F RF F+     C SF YGGC  N NNF T++EC  +C+
Sbjct:  726 VMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCV 788

HSP 5 Score: 57.3806 bits (137), Expect = 2.521e-10
Identity = 23/52 (44.23%), Postives = 31/52 (59.62%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +C +P + G C  +  R+YFN+  G C  F YGGC  N N+F T +ECE  C
Sbjct:  953 KCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1004

HSP 6 Score: 55.0694 bits (131), Expect = 1.544e-9
Identity = 26/64 (40.62%), Postives = 33/64 (51.56%), Query Frame = 3

Query:  138 FSLGESRA---PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +S+  SR     EC      G C   F R+++N  S  CE F Y GC  NGNN+ + E CE RC
Sbjct:  281 YSIQSSRTVNTKECVGVSLPGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 344

HSP 7 Score: 51.2174 bits (121), Expect = 3.397e-8
Identity = 21/65 (32.31%), Postives = 36/65 (55.38%), Query Frame = 3

Query:  162 PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQTFEISKI 356
            P C +P   G C     R+Y++  + +C  F Y GC  N NNF ++E+C+  C+  +Q+ +  K+
Sbjct: 2611 PLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCVLNIQSIKNGKV 2675

HSP 8 Score: 45.4394 bits (106), Expect = 3.906e-6
Identity = 19/51 (37.25%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+  K +G    Y  ++YFN+++  CE F++ G   N N F T+ ECE  C
Sbjct: 2112 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERIC 2162

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3h.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 64.3142 bits (155), Expect = 1.073e-12
Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 3

Query:  153 SRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +RA  C+ PK+ G C  Y  RFYFN     C+ F +GGC+ N NNF  +E+CE+ C
Sbjct:  313 ARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 368

HSP 2 Score: 60.8474 bits (146), Expect = 1.853e-11
Identity = 24/52 (46.15%), Postives = 30/52 (57.69%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C  P   G+C  Y PR++FN Q+G CE F YG C  N NNF     CE +C+
Sbjct: 1575 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKCM 1626

HSP 3 Score: 59.3066 bits (142), Expect = 5.569e-11
Identity = 24/51 (47.06%), Postives = 32/51 (62.75%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C  P+ +G C   F R++F+ +  NC+ F Y GCQ NGNNF + EEC A C
Sbjct:  516 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 566

HSP 4 Score: 57.7658 bits (138), Expect = 2.068e-10
Identity = 24/63 (38.10%), Postives = 34/63 (53.97%), Query Frame = 3

Query:  135 IFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            + ++ +S    C    + G CA  F RF F+     C SF YGGC  N NNF T++EC  +C+
Sbjct:  634 VMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCV 696

HSP 5 Score: 56.9954 bits (136), Expect = 3.515e-10
Identity = 23/52 (44.23%), Postives = 31/52 (59.62%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +C +P + G C  +  R+YFN+  G C  F YGGC  N N+F T +ECE  C
Sbjct:  861 KCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 912

HSP 6 Score: 54.6842 bits (130), Expect = 2.216e-9
Identity = 26/64 (40.62%), Postives = 33/64 (51.56%), Query Frame = 3

Query:  138 FSLGESRA---PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +S+  SR     EC      G C   F R+++N  S  CE F Y GC  NGNN+ + E CE RC
Sbjct:  189 YSIQSSRTVNTKECVGVSLPGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 252

HSP 7 Score: 50.8322 bits (120), Expect = 4.734e-8
Identity = 21/65 (32.31%), Postives = 36/65 (55.38%), Query Frame = 3

Query:  162 PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQTFEISKI 356
            P C +P   G C     R+Y++  + +C  F Y GC  N NNF ++E+C+  C+  +Q+ +  K+
Sbjct: 2138 PLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCVLNIQSIKNGKV 2202

HSP 8 Score: 45.0542 bits (105), Expect = 5.134e-6
Identity = 19/51 (37.25%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+  K +G    Y  ++YFN+++  CE F++ G   N N F T+ ECE  C
Sbjct: 1639 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERIC 1689

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 63.929 bits (154), Expect = 1.242e-12
Identity = 26/56 (46.43%), Postives = 35/56 (62.50%), Query Frame = 3

Query:  153 SRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +RA  C+ PK+ G C  Y  RFYFN     C+ F +GGC+ N NNF  +E+CE+ C
Sbjct:  534 ARATRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 2 Score: 60.4622 bits (145), Expect = 2.023e-11
Identity = 24/52 (46.15%), Postives = 30/52 (57.69%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C  P   G+C  Y PR++FN Q+G CE F YG C  N NNF     CE +C+
Sbjct: 1651 CAMPPDAGVCTNYTPRWFFNSQTGQCEQFAYGSCGGNENNFFDRNTCERKCM 1702

HSP 3 Score: 59.3066 bits (142), Expect = 6.198e-11
Identity = 24/51 (47.06%), Postives = 32/51 (62.75%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C  P+ +G C   F R++F+ +  NC+ F Y GCQ NGNNF + EEC A C
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 787

HSP 4 Score: 57.7658 bits (138), Expect = 2.194e-10
Identity = 24/63 (38.10%), Postives = 34/63 (53.97%), Query Frame = 3

Query:  135 IFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            + ++ +S    C    + G CA  F RF F+     C SF YGGC  N NNF T++EC  +C+
Sbjct:  855 VMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCV 917

HSP 5 Score: 56.9954 bits (136), Expect = 3.875e-10
Identity = 23/52 (44.23%), Postives = 31/52 (59.62%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +C +P + G C  +  R+YFN+  G C  F YGGC  N N+F T +ECE  C
Sbjct: 1082 KCLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1133

HSP 6 Score: 54.6842 bits (130), Expect = 2.419e-9
Identity = 26/64 (40.62%), Postives = 33/64 (51.56%), Query Frame = 3

Query:  138 FSLGESRA---PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +S+  SR     EC      G C   F R+++N  S  CE F Y GC  NGNN+ + E CE RC
Sbjct:  410 YSIQSSRTVNTKECVGVSLPGPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 7 Score: 50.8322 bits (120), Expect = 5.167e-8
Identity = 21/65 (32.31%), Postives = 36/65 (55.38%), Query Frame = 3

Query:  162 PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQTFEISKI 356
            P C +P   G C     R+Y++  + +C  F Y GC  N NNF ++E+C+  C+  +Q+ +  K+
Sbjct: 2214 PLCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCVLNIQSIKNGKV 2278

HSP 8 Score: 45.0542 bits (105), Expect = 5.547e-6
Identity = 19/51 (37.25%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+  K +G    Y  ++YFN+++  CE F++ G   N N F T+ ECE  C
Sbjct: 1715 CSFDKDSGSGKGYNVKWYFNMKNLRCEQFVFEGLGGNTNQFETLSECERIC 1765

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0077545)

HSP 1 Score: 66.6254 bits (161), Expect = 8.937e-15
Identity = 26/53 (49.06%), Postives = 38/53 (71.70%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            +C++PK+TG C A F R+ +N+ + +CE F+YGGC  N NNF + E+CE  CL
Sbjct:   54 DCHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQACL 106

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Fly
Match: CG3604 (gene:FBgn0031562 transcript:FBtr0346581)

HSP 1 Score: 66.6254 bits (161), Expect = 8.937e-15
Identity = 26/53 (49.06%), Postives = 38/53 (71.70%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            +C++PK+TG C A F R+ +N+ + +CE F+YGGC  N NNF + E+CE  CL
Sbjct:   54 DCHQPKETGRCFALFYRYAYNVDTQSCEEFVYGGCAGNKNNFESKEQCEQACL 106

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Fly
Match: CG15418 (gene:FBgn0031554 transcript:FBtr0077556)

HSP 1 Score: 60.8474 bits (146), Expect = 6.869e-13
Identity = 26/56 (46.43%), Postives = 37/56 (66.07%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQ 335
            C +PK  G+C  +  R+ +N ++GNCESFIY GC +  NNF T EEC   C++ L+
Sbjct:   41 CRQPKAPGLCRGHQLRYAYNKKTGNCESFIYTGCASTENNFLTFEECRRDCMQRLR 96

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Fly
Match: CG15418 (gene:FBgn0031554 transcript:FBtr0446100)

HSP 1 Score: 60.8474 bits (146), Expect = 6.869e-13
Identity = 26/56 (46.43%), Postives = 37/56 (66.07%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQ 335
            C +PK  G+C  +  R+ +N ++GNCESFIY GC +  NNF T EEC   C++ L+
Sbjct:   41 CRQPKAPGLCRGHQLRYAYNKKTGNCESFIYTGCASTENNFLTFEECRRDCMQRLR 96

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Fly
Match: Ppn (gene:FBgn0003137 transcript:FBtr0301839)

HSP 1 Score: 59.6918 bits (143), Expect = 6.019e-11
Identity = 25/52 (48.08%), Postives = 31/52 (59.62%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            CNEP  TG C  +  ++YFN  S  CE F YGGC   GN F+ + EC+  CL
Sbjct: 2196 CNEPVTTGPCTDWQTKYYFNTASQACEPFTYGGCDGTGNRFSDLFECQTVCL 2247

HSP 2 Score: 54.6842 bits (130), Expect = 3.138e-9
Identity = 23/52 (44.23%), Postives = 30/52 (57.69%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +C++P   G C  +   + +N   G C+SF YGGC  N N F T EEC ARC
Sbjct: 1943 QCSQPADPGQCDKWALHWNYNETEGRCQSFYYGGCGGNDNRFATEEECSARC 1994

HSP 3 Score: 53.5286 bits (127), Expect = 6.400e-9
Identity = 21/53 (39.62%), Postives = 31/53 (58.49%), Query Frame = 3

Query:  162 PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            P C +P ++G CA  F R+Y++ ++  C  F YGGC+ N NN+ T   C   C
Sbjct: 1728 PTCEQPVESGPCAGNFERWYYDNETDICRPFTYGGCKGNKNNYPTEHACNYNC 1780

HSP 4 Score: 53.1434 bits (126), Expect = 1.087e-8
Identity = 22/51 (43.14%), Postives = 28/51 (54.90%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C  PK+TG C  Y  ++YF+   G C  F YGGC  N N F +  EC+  C
Sbjct: 1612 CGLPKETGTCNNYSVKYYFDTSYGGCARFWYGGCDGNDNRFESEAECKDTC 1662

HSP 5 Score: 52.7582 bits (125), Expect = 1.479e-8
Identity = 19/51 (37.25%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C  PK  G C  +  ++YF++    CE F YGGC    N F+++E+C+  C
Sbjct: 1671 CLLPKSAGPCTGFTKKWYFDVDRNRCEEFQYGGCYGTNNRFDSLEQCQGTC 1721

HSP 6 Score: 52.373 bits (124), Expect = 1.759e-8
Identity = 23/51 (45.10%), Postives = 27/51 (52.94%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C  P + G CA Y   +Y++ Q   C  F YGGC  N N F T E C ARC
Sbjct: 1792 CEIPAEVGECANYVTSWYYDTQDQACRQFYYGGCGGNENRFPTEESCLARC 1842

HSP 7 Score: 51.9878 bits (123), Expect = 2.281e-8
Identity = 22/57 (38.60%), Postives = 32/57 (56.14%), Query Frame = 3

Query:  153 SRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            SR   C+E    G C+ +  +++F+ + G C  F YG C  NGN F T  +C+ RCL
Sbjct: 1860 SRQDVCDEEPAPGECSTWVLKWHFDRKIGACRQFYYGNCGGNGNRFETENDCQQRCL 1916

HSP 8 Score: 50.447 bits (119), Expect = 9.940e-8
Identity = 23/54 (42.59%), Postives = 32/54 (59.26%), Query Frame = 3

Query:  168 CNEPKKTGMC---AAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C  P  TG C   + +  R+Y++ ++GNC SFIY GC  N NNF + E C  +C
Sbjct: 2261 CLLPVATGRCNGPSVHERRWYYDDEAGNCVSFIYAGCSGNQNNFRSFEACTNQC 2314

HSP 9 Score: 48.9062 bits (115), Expect = 2.945e-7
Identity = 25/72 (34.72%), Postives = 38/72 (52.78%), Query Frame = 3

Query:  120 LIFCVIFSLGESRAPE---CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            L FC+   + E  AP    C EP + G C      ++++ ++  C +F Y GC  NGN F T ++CE +C E
Sbjct: 2118 LNFCIGEPVVEPSAPTYSVCAEPPEAGECDNRTTAWFYDSENMACTAFTYTGCGGNGNRFETRDQCERQCGE 2189

HSP 10 Score: 45.4394 bits (106), Expect = 5.193e-6
Identity = 20/57 (35.09%), Postives = 29/57 (50.88%), Query Frame = 3

Query:  150 ESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            E    +C    + G C     R+++N   G C+ F+Y GC  N NN+ T EEC+  C
Sbjct: 2008 EHDTSKCFLAFEPGNCYNNVTRWFYNSAEGLCDEFVYTGCGGNANNYATEEECQNEC 2064

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Zebrafish
Match: tfpia (tissue factor pathway inhibitor a [Source:ZFIN;Acc:ZDB-GENE-030711-1])

HSP 1 Score: 63.5438 bits (153), Expect = 1.633e-12
Identity = 28/52 (53.85%), Postives = 33/52 (63.46%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C   K  G C A   RFYF+I +G CE F YGGCQ N NNF T+++CE  CL
Sbjct:   42 CALKKDEGPCKAMKDRFYFDIDTGRCEPFEYGGCQGNANNFETLQDCEEMCL 93

HSP 2 Score: 54.6842 bits (130), Expect = 2.472e-9
Identity = 24/57 (42.11%), Postives = 36/57 (63.16%), Query Frame = 3

Query:  150 ESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            E+++P C+   + G C    PR++F+ +S  C+ F YGGC  N NNF TI+ C+ RC
Sbjct:   96 ENKSP-CHLEDEPGPCRGLVPRYFFDQKSQECKQFFYGGCFGNANNFKTIKACQQRC 151

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Zebrafish
Match: tfpia (tissue factor pathway inhibitor a [Source:ZFIN;Acc:ZDB-GENE-030711-1])

HSP 1 Score: 63.5438 bits (153), Expect = 1.829e-12
Identity = 28/52 (53.85%), Postives = 33/52 (63.46%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C   K  G C A   RFYF+I +G CE F YGGCQ N NNF T+++CE  CL
Sbjct:   41 CALKKDEGPCKAMKDRFYFDIDTGRCEPFEYGGCQGNANNFETLQDCEEMCL 92

HSP 2 Score: 54.6842 bits (130), Expect = 2.637e-9
Identity = 24/57 (42.11%), Postives = 36/57 (63.16%), Query Frame = 3

Query:  150 ESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            E+++P C+   + G C    PR++F+ +S  C+ F YGGC  N NNF TI+ C+ RC
Sbjct:   95 ENKSP-CHLEDEPGPCRGLVPRYFFDQKSQECKQFFYGGCFGNANNFKTIKACQQRC 150

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Zebrafish
Match: spint2 (serine peptidase inhibitor, Kunitz type, 2 [Source:ZFIN;Acc:ZDB-GENE-061013-323])

HSP 1 Score: 61.6178 bits (148), Expect = 1.323e-11
Identity = 28/53 (52.83%), Postives = 33/53 (62.26%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
             C  P   G C A FPRF+++I    C+SFIYGGC  N NNF +  ECEA CL
Sbjct:  132 HCRFPSAVGNCRAAFPRFFYDITDQTCKSFIYGGCGGNENNFYSQAECEASCL 184

HSP 2 Score: 48.521 bits (114), Expect = 5.051e-7
Identity = 23/52 (44.23%), Postives = 30/52 (57.69%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +C  P  TG C A   RFY+N  +G C+ FIYGGC  N NN+ + + C   C
Sbjct:  227 KCQSPAVTGNCRASIKRFYYN--NGVCQQFIYGGCGGNKNNYESEDSCMTAC 276

HSP 3 Score: 48.1358 bits (113), Expect = 5.403e-7
Identity = 33/100 (33.00%), Postives = 47/100 (47.00%), Query Frame = 3

Query:   21 NNYKIFDYKLTIKYNSIQIFIIKPKMNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            NNY+  D  +T    +  + II  +    VI       I     S   +C  P  +G C A F  F+F   S +C+ FIYGGC+ N N + + EEC + C
Sbjct:  264 NNYESEDSCMT----ACTVKIIPKEQEGPVIP-----AIPKSAHSFEEKCVVPSDSGPCRASFRMFFFEASSQSCQPFIYGGCRGNLNRYGSEEECMSVC 354

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Zebrafish
Match: spint2 (serine peptidase inhibitor, Kunitz type, 2 [Source:ZFIN;Acc:ZDB-GENE-061013-323])

HSP 1 Score: 61.6178 bits (148), Expect = 1.361e-11
Identity = 28/53 (52.83%), Postives = 33/53 (62.26%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
             C  P   G C A FPRF+++I    C+SFIYGGC  N NNF +  ECEA CL
Sbjct:  132 HCRFPSAVGNCRAAFPRFFYDITDQTCKSFIYGGCGGNENNFYSQAECEASCL 184

HSP 2 Score: 48.521 bits (114), Expect = 5.149e-7
Identity = 23/52 (44.23%), Postives = 30/52 (57.69%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +C  P  TG C A   RFY+N  +G C+ FIYGGC  N NN+ + + C   C
Sbjct:  227 KCQSPAVTGNCRASIKRFYYN--NGVCQQFIYGGCGGNKNNYESEDSCMTAC 276

HSP 3 Score: 48.1358 bits (113), Expect = 5.455e-7
Identity = 33/100 (33.00%), Postives = 47/100 (47.00%), Query Frame = 3

Query:   21 NNYKIFDYKLTIKYNSIQIFIIKPKMNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            NNY+  D  +T    +  + II  +    VI       I     S   +C  P  +G C A F  F+F   S +C+ FIYGGC+ N N + + EEC + C
Sbjct:  264 NNYESEDSCMT----ACTVKIIPKEQEGPVIP-----AIPKSAHSFEEKCVVPSDSGPCRASFRMFFFEASSQSCQPFIYGGCRGNLNRYGSEEECMSVC 354

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Zebrafish
Match: appb (amyloid beta (A4) precursor protein b [Source:ZFIN;Acc:ZDB-GENE-020220-1])

HSP 1 Score: 60.077 bits (144), Expect = 5.085e-11
Identity = 24/51 (47.06%), Postives = 30/51 (58.82%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C  P ++G C A  PR+YF  + G C SF +GGC  N NNF + E C A C
Sbjct:  306 CWAPARSGPCHAKLPRWYFVAEKGRCASFTFGGCGGNRNNFESEEYCMAVC 356

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Xenopus
Match: WFIKKN2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:NCBI gene;Acc:100486381])

HSP 1 Score: 63.5438 bits (153), Expect = 4.197e-12
Identity = 29/51 (56.86%), Postives = 32/51 (62.75%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            CN P   GMC AY PR+ +N Q   C+SFIYGGC  N NNF T E CE  C
Sbjct:  370 CNFPALQGMCKAYKPRWAYNKQLKQCQSFIYGGCGGNDNNFETKETCEDMC 420

HSP 2 Score: 46.2098 bits (108), Expect = 4.380e-6
Identity = 21/53 (39.62%), Postives = 30/53 (56.60%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            EC +P  +  C     R+YF+ +  NC  FIYG C +N N+F+T E C   C+
Sbjct:  311 ECLKPPDSDDCGEEQTRWYFDAKKNNCFIFIYGNCNSNYNHFDTYESCMLTCM 363

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Xenopus
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:NCBI gene;Acc:548483])

HSP 1 Score: 59.3066 bits (142), Expect = 4.908e-11
Identity = 29/65 (44.62%), Postives = 38/65 (58.46%), Query Frame = 3

Query:  129 CVIFSLGESRAPE-CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+ F      AP  C  PK  G C+A   R+YFNI+S  CE F+Y GC  N NNF  +E+C++ C
Sbjct:  135 CMDFCSPRRDAPSFCYSPKDEGSCSASVTRYYFNIESKACEEFVYTGCGGNSNNFVKMEDCDSVC 199

HSP 2 Score: 52.373 bits (124), Expect = 1.645e-8
Identity = 23/77 (29.87%), Postives = 40/77 (51.95%), Query Frame = 3

Query:   96 MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            + +++  +L+  V  S  +     C  P   G C A  P +Y++  +  C+ F+YGGC  N N F ++E+CE  C +
Sbjct:    5 LQALMAASLLIQVFGSPMQGNTTVCLLPPDEGPCKALIPHYYYDRYTQTCQEFLYGGCDGNSNKFLSMEDCEKFCWK 81

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Xenopus
Match: spint2 (serine peptidase inhibitor, Kunitz type, 2 [Source:NCBI gene;Acc:733874])

HSP 1 Score: 57.7658 bits (138), Expect = 3.856e-10
Identity = 25/54 (46.30%), Postives = 32/54 (59.26%), Query Frame = 3

Query:  162 PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            P C      G C A FPR+YF+ +S NC SF YGGC    NN  +++EC  RC+
Sbjct:  194 PACTGKGVIGNCRASFPRWYFDAESQNCISFTYGGCGGTENNHKSVQECADRCI 247

HSP 2 Score: 53.1434 bits (126), Expect = 1.413e-8
Identity = 23/62 (37.10%), Postives = 34/62 (54.84%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQTFEISK 353
            C  P  TG C A F R+Y+++ +  C +F YGGC+ N NN+ ++E+C   C   L     S 
Sbjct:  268 CAAPSLTGPCRASFRRWYYDVTTATCVAFTYGGCRGNKNNYLSVEDCVKNCAGRLDDDHTSD 329

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Xenopus
Match: ENSXETT00000011536.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV462126.1:486:923:1 gene:ENSXETG00000005815.1 transcript:ENSXETT00000011536.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.299 bits (129), Expect = 4.699e-10
Identity = 23/47 (48.94%), Postives = 29/47 (61.70%), Query Frame = 3

Query:  183 KTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            K+G C A  P++Y+N + G C SF+Y GCQ NGN F   E C   CL
Sbjct:    9 KSGPCLALIPQWYYNKERGACHSFLYSGCQGNGNRFENKENCTTLCL 55

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Xenopus
Match: APLP2 (amyloid beta (A4) precursor-like protein 2 [Source:NCBI gene;Acc:100380132])

HSP 1 Score: 57.3806 bits (137), Expect = 4.908e-10
Identity = 23/51 (45.10%), Postives = 30/51 (58.82%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C++   TG C A  PR+YF++    C  FIYGGC  N NNF + + C A C
Sbjct:  297 CSQEAMTGPCRAMMPRWYFDLGQKKCVRFIYGGCGGNRNNFESEDYCMAVC 347

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Mouse
Match: Wfikkn2 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:MGI Symbol;Acc:MGI:2669209])

HSP 1 Score: 68.5514 bits (166), Expect = 4.760e-14
Identity = 27/51 (52.94%), Postives = 35/51 (68.63%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+ P   G C AY PR+ +N Q+G C+SF+YGGC+ NGNNF + E CE  C
Sbjct:  381 CSLPALQGPCKAYVPRWAYNSQTGLCQSFVYGGCEGNGNNFESREACEESC 431

HSP 2 Score: 46.595 bits (109), Expect = 2.424e-6
Identity = 20/55 (36.36%), Postives = 30/55 (54.55%), Query Frame = 3

Query:  159 APECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            A EC +P  +  C     R++F+ Q+ NC +F +G C  N N+F T E C   C+
Sbjct:  320 ATECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHHNLNHFETYEACMLACM 374

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Mouse
Match: Spint5 (serine protease inhibitor, Kunitz type 5 [Source:MGI Symbol;Acc:MGI:3651687])

HSP 1 Score: 60.077 bits (144), Expect = 2.390e-12
Identity = 28/53 (52.83%), Postives = 34/53 (64.15%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            CN+P K G C+  F R+YFN +S  CESFI+ GC  N NNF T   CE RC+ 
Sbjct:   49 CNQPVKKGFCSFTFYRYYFNPESALCESFIFTGCGGNRNNFKTKYLCEVRCIH 101

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Mouse
Match: Spint5 (serine protease inhibitor, Kunitz type 5 [Source:MGI Symbol;Acc:MGI:3651687])

HSP 1 Score: 60.077 bits (144), Expect = 2.776e-12
Identity = 28/53 (52.83%), Postives = 34/53 (64.15%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            CN+P K G C+  F R+YFN +S  CESFI+ GC  N NNF T   CE RC+ 
Sbjct:   49 CNQPVKKGFCSFTFYRYYFNPESALCESFIFTGCGGNRNNFKTKYLCEVRCIH 101

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Mouse
Match: Spint2 (serine protease inhibitor, Kunitz type 2 [Source:MGI Symbol;Acc:MGI:1338031])

HSP 1 Score: 62.7734 bits (151), Expect = 2.842e-12
Identity = 24/51 (47.06%), Postives = 34/51 (66.67%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C   K  G C A  PR+++NI  G+C+ F+YGGC+ NGNN+ + EEC  +C
Sbjct:   38 CGVSKVVGKCRASIPRWWYNITDGSCQPFVYGGCEGNGNNYQSKEECLDKC 88

HSP 2 Score: 51.2174 bits (121), Expect = 4.740e-8
Identity = 21/45 (46.67%), Postives = 30/45 (66.67%), Query Frame = 3

Query:  186 TGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            TG C A FPR+Y++ +  +C SFIYGGC+ N N++ + E C   C
Sbjct:  139 TGPCRAAFPRWYYDTEKNSCISFIYGGCRGNKNSYLSQEACMQHC 183

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Mouse
Match: Spint3 (serine peptidase inhibitor, Kunitz type, 3 [Source:MGI Symbol;Acc:MGI:3651470])

HSP 1 Score: 58.9214 bits (141), Expect = 4.599e-12
Identity = 27/57 (47.37%), Postives = 36/57 (63.16%), Query Frame = 3

Query:  150 ESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +S  P C  PK  G C A F R+Y+N ++G CE F YGGC+ N NNF +  +C+A C
Sbjct:   29 KSLPPMCILPKDIGGCRAVFVRWYYNSKTGKCEWFRYGGCKGNENNFPSRSQCQAVC 85

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. UniProt/SwissProt
Match: sp|P0DMJ5|VKT_HETCR (PI-stichotoxin-Hcr2e OS=Heteractis crispa OX=175771 PE=1 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 3.663e-18
Identity = 37/76 (48.68%), Postives = 45/76 (59.21%), Query Frame = 3

Query:   96 MNSIVIFTLIFCVIFSLGESRAPE-CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            M    +  LI    FS   ++A   C EPK  G C AYFPRFYF+ ++G C  FIYGGC+ NGNNF T+  C A C
Sbjct:    1 MKGTFLICLILIAGFSFKSTQAGSICLEPKVVGPCTAYFPRFYFDSETGKCTPFIYGGCEGNGNNFETLHACRAIC 76

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. UniProt/SwissProt
Match: sp|P83606|BMTI6_RHIMP (Kunitz-type serine protease inhibitor 6 (Fragment) OS=Rhipicephalus microplus OX=6941 PE=1 SV=2)

HSP 1 Score: 80.1073 bits (196), Expect = 1.030e-17
Identity = 36/58 (62.07%), Postives = 43/58 (74.14%), Query Frame = 3

Query:  162 PECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQ 335
            P CNEPK   +C  YFPR+Y+N +S  C+ FIYGGCQ+NGNNF T+EECE  CL  LQ
Sbjct:  233 PVCNEPKYPELCKGYFPRYYYNSRSKTCKKFIYGGCQSNGNNFLTLEECENTCLVDLQ 290

HSP 2 Score: 70.8626 bits (172), Expect = 2.773e-14
Identity = 29/52 (55.77%), Postives = 36/52 (69.23%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C     +G C  YFPR++FN+++G CE FIYGGCQ N NN  T +ECE RCL
Sbjct:    7 CKPTYDSGPCKGYFPRWWFNVKTGQCEEFIYGGCQGNKNNHVTRKECETRCL 58

HSP 3 Score: 65.855 bits (159), Expect = 1.987e-12
Identity = 27/52 (51.92%), Postives = 33/52 (63.46%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C      G C AY PR++FN+++G CE FIYGGCQ N NN+ T   CE  CL
Sbjct:  139 CKPTHDRGPCKAYIPRWWFNVKTGQCEQFIYGGCQGNKNNYETKSICETNCL 190

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. UniProt/SwissProt
Match: sp|B2G331|VKT1_HETCR (TauPI-stichotoxin-Hcr2b OS=Heteractis crispa OX=175771 PE=1 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 1.177e-16
Identity = 36/76 (47.37%), Postives = 44/76 (57.89%), Query Frame = 3

Query:   96 MNSIVIFTLIFCVIFSLGESRAPE-CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            M    +  LI    FS   ++A   C EPK  G C AYF RFYF+ ++G C  FIYGGC+ NGNNF T+  C A C
Sbjct:    1 MKGTFLICLILIAGFSFKSTQAGSICLEPKVVGPCTAYFRRFYFDSETGKCTVFIYGGCEGNGNNFETLRACRAIC 76

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. UniProt/SwissProt
Match: sp|C0HK74|VKT3_HETMG (Kunitz-type serine protease inhibitor HMGS2 OS=Heteractis magnifica OX=38281 PE=1 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 1.352e-16
Identity = 31/51 (60.78%), Postives = 36/51 (70.59%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C EPK  G C AYFPRFYF+ ++G C  FIYGGC+ NGNNF T+  C A C
Sbjct:    4 CLEPKVVGPCTAYFPRFYFDSETGKCTPFIYGGCEGNGNNFETLHACRAIC 54

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. UniProt/SwissProt
Match: sp|P0DN09|VKT5_ANEVI (U-actitoxin-Avd3h OS=Anemonia viridis OX=51769 PE=3 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 1.828e-16
Identity = 33/71 (46.48%), Postives = 44/71 (61.97%), Query Frame = 3

Query:  108 VIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            ++F L F ++  +      +C  PK  G C A FPR+Y+N  S  CE FIYGGC+ N NNF+T+EECE  C
Sbjct:    1 MVFLLCFFLVADVSYGINGDCELPKVVGPCRARFPRYYYNSSSKRCEKFIYGGCRGNANNFHTLEECEKVC 71

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. TrEMBL
Match: C1IBY4 (Tabserpin OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 85.8853 bits (211), Expect = 2.337e-19
Identity = 37/75 (49.33%), Postives = 50/75 (66.67%), Query Frame = 3

Query:   96 MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            M  + +  ++F V+     ++ P C++PK  G C A FP+FYFN  SG CE+FIYGGC  N NNFNT+EEC A+C
Sbjct:    1 MKVLSLIFVLFSVLVLFASAKDPVCDQPKAVGRCFAAFPKFYFNSSSGQCEAFIYGGCGGNENNFNTLEECNAKC 75

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. TrEMBL
Match: C8YJ95 (Serine protease inhibitor 3 OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 5.643e-19
Identity = 37/75 (49.33%), Postives = 50/75 (66.67%), Query Frame = 3

Query:   96 MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            M  + +  +IF V+     ++ P C++PK  G C A FP+FYFN  SG CE+FIYGGC  N NNF+T+EEC A+C
Sbjct:    1 MKVLSLIFVIFSVLVLFASAKDPVCDQPKAVGRCFAAFPKFYFNSSSGQCEAFIYGGCGGNENNFSTLEECNAKC 75

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. TrEMBL
Match: C8YJ94 (Serine protease inhibitor 2 OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 8.532e-19
Identity = 36/75 (48.00%), Postives = 50/75 (66.67%), Query Frame = 3

Query:   96 MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            M  + +  +IF V+     ++ P C++PK  G C A FP+FY+N  SG C++FIYGGC  N NNFNT+EEC A+C
Sbjct:    1 MKVLSLIFVIFSVLVLFASAKDPVCDQPKAVGRCFAAFPKFYYNSSSGQCQAFIYGGCGGNENNFNTLEECNAKC 75

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. TrEMBL
Match: C8YJ97 (Serine protease inhibitor 5 OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 3.547e-18
Identity = 37/75 (49.33%), Postives = 48/75 (64.00%), Query Frame = 3

Query:   96 MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            M  + +  +IF V+     ++ P C++PK    C A FP+FYFN  SG CE FIYGGC  N NNFNT+EEC A+C
Sbjct:    1 MKVLSLIFVIFSVLVLFASAKDPVCDQPKAVRRCFAAFPKFYFNSSSGQCEGFIYGGCGGNENNFNTLEECNAKC 75

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. TrEMBL
Match: C8YJ96 (Serine protease inhibitor 4 OS=Tabanus yao OX=485572 PE=2 SV=1)

HSP 1 Score: 78.9518 bits (193), Expect = 1.031e-16
Identity = 35/75 (46.67%), Postives = 47/75 (62.67%), Query Frame = 3

Query:   96 MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            M  + +  +IF V+     ++ P C++PK  G C A FP+FYFN  S   E+F YGGC  N NNFNT+EEC A+C
Sbjct:    1 MKVLSLIFVIFSVLVLFASAKDPVCDQPKAVGRCFAAFPKFYFNSSSAQGEAFFYGGCGGNENNFNTLEECNAKC 75

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Cavefish
Match: ENSAMXT00000015806.2 (tissue factor pathway inhibitor-like [Source:NCBI gene;Acc:103025270])

HSP 1 Score: 64.6994 bits (156), Expect = 6.005e-13
Identity = 28/48 (58.33%), Postives = 33/48 (68.75%), Query Frame = 3

Query:  180 KKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            K  G C A   RFYF+I SG CESF YGGCQ N NNF T+++CE  C+
Sbjct:   40 KDEGPCKAVKDRFYFDIDSGRCESFEYGGCQGNANNFQTLDQCEEMCV 87

HSP 2 Score: 52.7582 bits (125), Expect = 9.849e-9
Identity = 25/65 (38.46%), Postives = 37/65 (56.92%), Query Frame = 3

Query:  126 FCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
             CV+    E+++P C+   + G C    PR++F+ +   C  F YGGC  N NNF T++EC  RC
Sbjct:   85 MCVV---KENKSP-CHLEDEPGPCRGLVPRYFFDSRKQECRRFFYGGCFGNANNFKTLKECRDRC 145

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Cavefish
Match: paplnb (papilin-like [Source:NCBI gene;Acc:103035042])

HSP 1 Score: 64.3142 bits (155), Expect = 1.265e-12
Identity = 28/56 (50.00%), Postives = 33/56 (58.93%), Query Frame = 3

Query:  159 APECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            A  C+ P+  G C  Y  RFYF+  +  C  F YGGCQ NGNNF T+EEC   C E
Sbjct:  465 AEVCSLPRDVGSCYEYKSRFYFDSSARTCTQFWYGGCQGNGNNFATVEECRRMCGE 520

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Cavefish
Match: paplnb (papilin-like [Source:NCBI gene;Acc:103035042])

HSP 1 Score: 63.929 bits (154), Expect = 1.772e-12
Identity = 28/56 (50.00%), Postives = 33/56 (58.93%), Query Frame = 3

Query:  159 APECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            A  C+ P+  G C  Y  RFYF+  +  C  F YGGCQ NGNNF T+EEC   C E
Sbjct:  494 AEVCSLPRDVGSCYEYKSRFYFDSSARTCTQFWYGGCQGNGNNFATVEECRRMCGE 549

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Cavefish
Match: wfikkn2b (WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 [Source:NCBI gene;Acc:103024700])

HSP 1 Score: 63.929 bits (154), Expect = 1.924e-12
Identity = 30/64 (46.88%), Postives = 38/64 (59.38%), Query Frame = 3

Query:  129 CVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C++   GE   P C+ P   G C AY PR+ ++I  G C+ FIYGGC+ N NNF T E CE  C
Sbjct:  362 CLLSCQGELAVP-CSLPSLQGPCKAYEPRWAYSITLGQCQPFIYGGCEGNENNFETRETCEDSC 424

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Cavefish
Match: lrp11 (LDL receptor related protein 11 [Source:NCBI gene;Acc:103032685])

HSP 1 Score: 60.8474 bits (146), Expect = 2.207e-11
Identity = 22/53 (41.51%), Postives = 32/53 (60.38%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            C EP   G C   FPR+Y++  +G C+ F+YGGC+ N NNF    +C   C++
Sbjct:  417 CMEPPVVGPCRGTFPRWYYDAAAGECKHFLYGGCKGNRNNFLQQTDCVNECIQ 469

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Sea Lamprey
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:ZFIN;Acc:ZDB-GENE-060503-38])

HSP 1 Score: 68.9366 bits (167), Expect = 1.887e-15
Identity = 32/62 (51.61%), Postives = 41/62 (66.13%), Query Frame = 3

Query:  135 IFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            +F+L + R   C  P K G C A FPR++FN  +  CESFIYGGC +N NNF T++EC A C
Sbjct:   17 VFTLEDQRV-TCTLPAKPGDCRAAFPRYFFNRSTLRCESFIYGGCHSNENNFETMQECRAAC 77

HSP 2 Score: 50.447 bits (119), Expect = 1.124e-8
Identity = 21/53 (39.62%), Postives = 30/53 (56.60%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            C    +TG C A+  R+++N+  G C  F+YGGC  N N F  +E C   C+E
Sbjct:   87 CRPDAETGRCRAHITRYFYNMTLGMCMPFVYGGCGGNNNRFEDMESCVFSCIE 139

HSP 3 Score: 48.9062 bits (115), Expect = 4.226e-8
Identity = 27/66 (40.91%), Postives = 34/66 (51.52%), Query Frame = 3

Query:  129 CVIFSLGESRAP-ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            CV   + +   P EC     TG C   F RFY+NIQ  +C  F Y GC  N NNF + + C + CL
Sbjct:  133 CVFSCIEKPNTPRECLSRHDTGNCQGNFRRFYYNIQKRSCLPFSYSGCGGNNNNFISAKTCLSTCL 198

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005038.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005038.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.299 bits (129), Expect = 4.608e-10
Identity = 23/44 (52.27%), Postives = 29/44 (65.91%), Query Frame = 3

Query:  189 GMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            G C AY PR ++N  +  CE F YGGC  NGNNF ++ EC A+C
Sbjct:   10 GPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKC 53

HSP 2 Score: 52.7582 bits (125), Expect = 1.495e-9
Identity = 27/66 (40.91%), Postives = 36/66 (54.55%), Query Frame = 3

Query:  159 APE-CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQTFEISK 353
            AP+ C    + G+C A   R++FN+ SG+CE F YGGCQ N NNF     C   C+      +I K
Sbjct:   71 APKACRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHCVHRAVPLKIKK 136

HSP 3 Score: 51.6026 bits (122), Expect = 3.834e-9
Identity = 22/44 (50.00%), Postives = 29/44 (65.91%), Query Frame = 3

Query:  189 GMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            G C A  PRF++N ++ NCESF YGGC  N NNF++   C + C
Sbjct:  174 GECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVC 217

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005043.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005043.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.9138 bits (128), Expect = 5.262e-10
Identity = 23/44 (52.27%), Postives = 29/44 (65.91%), Query Frame = 3

Query:  189 GMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            G C AY PR ++N  +  CE F YGGC  NGNNF ++ EC A+C
Sbjct:   10 GPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKC 53

HSP 2 Score: 52.7582 bits (125), Expect = 1.813e-9
Identity = 27/66 (40.91%), Postives = 36/66 (54.55%), Query Frame = 3

Query:  159 APE-CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE*LQTFEISK 353
            AP+ C    + G+C A   R++FN+ SG+CE F YGGCQ N NNF     C   C+      +I K
Sbjct:   70 APKACRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHCVHRAVPLKIKK 135

HSP 3 Score: 51.6026 bits (122), Expect = 4.292e-9
Identity = 22/44 (50.00%), Postives = 29/44 (65.91%), Query Frame = 3

Query:  189 GMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            G C A  PRF++N ++ NCESF YGGC  N NNF++   C + C
Sbjct:  173 GECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVC 216

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Sea Lamprey
Match: WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30912])

HSP 1 Score: 52.7582 bits (125), Expect = 2.658e-9
Identity = 21/60 (35.00%), Postives = 35/60 (58.33%), Query Frame = 3

Query:  141 SLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            ++ E  A EC+EP     C +   ++Y++     C++F+YGGC +N N F+T E C+  C
Sbjct:  332 AIAEFPASECHEPPDVTHCGSARTKWYYDSGLNACDTFVYGGCDSNRNRFDTYEGCKRWC 391

HSP 2 Score: 43.1282 bits (100), Expect = 6.076e-6
Identity = 18/51 (35.29%), Postives = 26/51 (50.98%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+ P   G C  +   + +N     C+  +YGGC+ N NNF + E CE  C
Sbjct:  399 CHLPPVQGPCRDWERHWAYNPLIKQCQLLVYGGCEGNENNFESREACEDNC 449

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008261.1 (pep scaffold:Pmarinus_7.0:GL478901:735:1448:1 gene:ENSPMAG00000007479.1 transcript:ENSPMAT00000008261.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.521 bits (114), Expect = 5.316e-8
Identity = 20/51 (39.22%), Postives = 29/51 (56.86%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C+ P   G C A+  R+ +N     C +F+YGGC+ NGN+F +   CE  C
Sbjct:   21 CSLPPVQGPCKAWETRWSYNPLGKRCATFLYGGCEGNGNSFASRSACERAC 71

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Nematostella
Match: EDO29819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2J6])

HSP 1 Score: 72.0182 bits (175), Expect = 6.504e-18
Identity = 31/52 (59.62%), Postives = 36/52 (69.23%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C  PKK G C A  PR +FN QSG CE FIYGGC  N NNF+T+EEC+  C+
Sbjct:   14 CTLPKKVGDCRAAMPRVFFNSQSGKCEDFIYGGCGGNANNFHTMEECKKACM 65

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Nematostella
Match: EDO41696 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 64.6994 bits (156), Expect = 3.617e-15
Identity = 28/52 (53.85%), Postives = 36/52 (69.23%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            EC +PK TG C AYF R+++N  S  C+ F+YGGCQ N NNF +  ECE +C
Sbjct:    1 ECLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Nematostella
Match: EDO26263 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3T1])

HSP 1 Score: 64.6994 bits (156), Expect = 3.617e-15
Identity = 28/52 (53.85%), Postives = 36/52 (69.23%), Query Frame = 3

Query:  165 ECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            EC +PK TG C AYF R+++N  S  C+ F+YGGCQ N NNF +  ECE +C
Sbjct:    1 ECLQPKLTGPCRAYFERWFYNQTSRKCKQFVYGGCQGNSNNFESKAECEKKC 52

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Nematostella
Match: EDO38284 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SDB9])

HSP 1 Score: 63.1586 bits (152), Expect = 1.925e-14
Identity = 27/52 (51.92%), Postives = 35/52 (67.31%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C  PK  G C A   RFY+N + G C+SF++GGC  NGNNF T + CEA+C+
Sbjct:   13 CKLPKFAGPCMASIERFYYNAKIGKCQSFVFGGCLPNGNNFKTRKACEAKCM 64

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Nematostella
Match: EDO41922 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S322])

HSP 1 Score: 59.6918 bits (143), Expect = 3.827e-13
Identity = 26/60 (43.33%), Postives = 37/60 (61.67%), Query Frame = 3

Query:  144 LGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            +G  +   C+ P  TG C AY P FY++++   C+ FIYGGC  N N F+T E+CE  C+
Sbjct:    1 MGGEQPSFCSLPAVTGRCMAYIPSFYYDMKEEKCKEFIYGGCNGNLNRFDTQEKCEEACM 60

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Medaka
Match: ENSORLT00000012975.2 (pep primary_assembly:ASM223467v1:12:15740273:15760140:1 gene:ENSORLG00000010354.2 transcript:ENSORLT00000012975.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.8474 bits (146), Expect = 5.266e-12
Identity = 26/52 (50.00%), Postives = 34/52 (65.38%), Query Frame = 3

Query:  168 CNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCL 323
            C +   +G+C  YF R+++N + G CE FIYGGC  N NNF T +EC  RCL
Sbjct:  125 CAQAPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQRCL 176

HSP 2 Score: 57.3806 bits (137), Expect = 1.015e-10
Identity = 26/61 (42.62%), Postives = 36/61 (59.02%), Query Frame = 3

Query:  135 IFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEAR 317
            + SL  +    C +   +G+C  YF R+++N + G CE FIYGGC  N NNF T +EC  R
Sbjct:   62 LVSLPSASTGVCAQAPDSGLCFGYFERYFYNFRKGRCEIFIYGGCLGNQNNFLTEKECLQR 122

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Medaka
Match: spint1a (kunitz-type protease inhibitor 1 [Source:NCBI gene;Acc:101175207])

HSP 1 Score: 62.003 bits (149), Expect = 7.367e-12
Identity = 33/82 (40.24%), Postives = 42/82 (51.22%), Query Frame = 3

Query:   93 KMNSIVIFTL------IFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            K N  VI T+      +  V+    E     C  PKK G C   FPR+Y+N  S  CE+F +GGC+ N NN+ T EEC   C
Sbjct:  203 KFNLTVIDTIGQSDSTVVTVLVLTPEQSMDHCLVPKKVGPCRGSFPRWYYNAASEKCETFFFGGCRQNKNNYLTEEECAMAC 284

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Medaka
Match: spint1a (serine peptidase inhibitor, Kunitz type 1 [Source:NCBI gene;Acc:101173105])

HSP 1 Score: 59.3066 bits (142), Expect = 6.786e-11
Identity = 28/68 (41.18%), Postives = 40/68 (58.82%), Query Frame = 3

Query:  117 TLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            T++  ++ +  ES    C  PKK G C   FPR+++N  S  CE FI+GGC+ N NN+   EEC+  C
Sbjct:  223 TVLTVLVLTPQESEH-HCMAPKKVGPCRGSFPRWHYNAASQKCEQFIFGGCRENRNNYLLEEECKFAC 289

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Medaka
Match: spint1a (serine peptidase inhibitor, Kunitz type 1 [Source:NCBI gene;Acc:101173105])

HSP 1 Score: 59.3066 bits (142), Expect = 7.365e-11
Identity = 28/68 (41.18%), Postives = 40/68 (58.82%), Query Frame = 3

Query:  117 TLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            T++  ++ +  ES    C  PKK G C   FPR+++N  S  CE FI+GGC+ N NN+   EEC+  C
Sbjct:  223 TVLTVLVLTPQESEH-HCMAPKKVGPCRGSFPRWHYNAASQKCEQFIFGGCRENRNNYLLEEECKFAC 289

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Medaka
Match: wfikkn2a (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [Source:NCBI gene;Acc:101168544])

HSP 1 Score: 58.5362 bits (140), Expect = 1.245e-10
Identity = 28/64 (43.75%), Postives = 37/64 (57.81%), Query Frame = 3

Query:  129 CVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            C++   GE  AP C+ P   G C AY PR+ ++     C+SF+YGGC  N NNF + E CE  C
Sbjct:  376 CMLACGGELAAP-CSLPSLQGPCKAYEPRWAYSSTLKKCQSFVYGGCGGNENNFESKEACEQMC 438

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Planmine SMEST
Match: SMESG000037994.1 (SMESG000037994.1)

HSP 1 Score: 159.458 bits (402), Expect = 6.557e-52
Identity = 77/77 (100.00%), Postives = 77/77 (100.00%), Query Frame = 3

Query:   96 MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE
Sbjct:    1 MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 77

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Planmine SMEST
Match: SMESG000037995.1 (SMESG000037995.1)

HSP 1 Score: 97.0561 bits (240), Expect = 2.833e-27
Identity = 45/72 (62.50%), Postives = 54/72 (75.00%), Query Frame = 3

Query:  120 LIFCVIFSLG---ESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            L+  V+FSL    ESR  ECNEPK++GMC AYF RFYFN ++G CE+FIYGGC  NGNNF T +ECE  C+E
Sbjct:    8 LVLVVLFSLSQLLESRLKECNEPKQSGMCMAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELCIE 79

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Planmine SMEST
Match: SMESG000037999.1 (SMESG000037999.1)

HSP 1 Score: 97.0561 bits (240), Expect = 3.194e-27
Identity = 45/72 (62.50%), Postives = 54/72 (75.00%), Query Frame = 3

Query:  120 LIFCVIFSLG---ESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            L+  V+FSL    ESR  ECNEPK++GMC AYF RFYFN ++G CE+FIYGGC  NGNNF T +ECE  C+E
Sbjct:    8 LVLVVLFSLSQLLESRLKECNEPKQSGMCEAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELCIE 79

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Planmine SMEST
Match: SMESG000037999.1 (SMESG000037999.1)

HSP 1 Score: 96.6709 bits (239), Expect = 3.298e-27
Identity = 45/72 (62.50%), Postives = 54/72 (75.00%), Query Frame = 3

Query:  120 LIFCVIFSLG---ESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARCLE 326
            L+  V+FSL    ESR  ECNEPK++GMC AYF RFYFN ++G CE+FIYGGC  NGNNF T +ECE  C+E
Sbjct:    6 LVLVVLFSLSQLLESRLKECNEPKQSGMCEAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELCIE 77

[Close]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Planmine SMEST
Match: SMESG000038052.1 (SMESG000038052.1)

HSP 1 Score: 96.6709 bits (239), Expect = 3.483e-27
Identity = 41/75 (54.67%), Postives = 55/75 (73.33%), Query Frame = 3

Query:   96 MNSIVIFTLIFCVIFSLGESRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIEECEARC 320
            MNS+VIF+ IF  +  L ES++PECN P +TG+C AYF R+ F+++ G C +F+YGGC  N NNF+T  ECE RC
Sbjct:    1 MNSLVIFSCIFVAVLQLTESKSPECNLPLETGLCEAYFVRYGFDVKLGKCRTFVYGGCHVNDNNFHTRAECEERC 75

The following BLAST results are available for this feature:

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Human
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Celegans
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Fly
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Zebrafish
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Xenopus
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Mouse
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. UniProt/SwissProt
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. TrEMBL
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Cavefish
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Sea Lamprey
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Yeast
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Nematostella
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Medaka
BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Planmine SMEST

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
WFIKKN2	2.623e-14	52.94	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
WFIKKN2	3.632e-14	52.94	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
APLP2	3.235e-11	47.06	amyloid beta precursor like protein 2 [Source:HGNC...	[more]
APLP2	3.240e-11	47.06	amyloid beta precursor like protein 2 [Source:HGNC...	[more]
APLP2	3.241e-11	47.06	amyloid beta precursor like protein 2 [Source:HGNC...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mlt-11	6.346e-13	46.43	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	7.057e-13	46.43	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]
mlt-11	7.328e-13	46.43	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	1.073e-12	46.43	pep chromosome:WBcel235:V:20667209:20678513:1 gene...	[more]
mlt-11	1.242e-12	46.43	pep chromosome:WBcel235:V:20667211:20678513:1 gene...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG3604	8.937e-15	49.06	gene:FBgn0031562 transcript:FBtr0077545	[more]
CG3604	8.937e-15	49.06	gene:FBgn0031562 transcript:FBtr0346581	[more]
CG15418	6.869e-13	46.43	gene:FBgn0031554 transcript:FBtr0077556	[more]
CG15418	6.869e-13	46.43	gene:FBgn0031554 transcript:FBtr0446100	[more]
Ppn	6.019e-11	48.08	gene:FBgn0003137 transcript:FBtr0301839	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfpia	1.633e-12	53.85	tissue factor pathway inhibitor a [Source:ZFIN;Acc...	[more]
tfpia	1.829e-12	53.85	tissue factor pathway inhibitor a [Source:ZFIN;Acc...	[more]
spint2	1.323e-11	52.83	serine peptidase inhibitor, Kunitz type, 2 [Source...	[more]
spint2	1.361e-11	52.83	serine peptidase inhibitor, Kunitz type, 2 [Source...	[more]
appb	5.085e-11	47.06	amyloid beta (A4) precursor protein b [Source:ZFIN...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
WFIKKN2	4.197e-12	56.86	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
tfpi2	4.908e-11	44.62	tissue factor pathway inhibitor 2 [Source:NCBI gen...	[more]
spint2	3.856e-10	46.30	serine peptidase inhibitor, Kunitz type, 2 [Source...	[more]
ENSXETT00000011536.1	4.699e-10	48.94	pep primary_assembly:Xenopus_tropicalis_v9.1:KV462...	[more]
APLP2	4.908e-10	45.10	amyloid beta (A4) precursor-like protein 2 [Source...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Wfikkn2	4.760e-14	52.94	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
Spint5	2.390e-12	52.83	serine protease inhibitor, Kunitz type 5 [Source:M...	[more]
Spint5	2.776e-12	52.83	serine protease inhibitor, Kunitz type 5 [Source:M...	[more]
Spint2	2.842e-12	47.06	serine protease inhibitor, Kunitz type 2 [Source:M...	[more]
Spint3	4.599e-12	47.37	serine peptidase inhibitor, Kunitz type, 3 [Source...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P0DMJ5\|VKT_HETCR	3.663e-18	48.68	PI-stichotoxin-Hcr2e OS=Heteractis crispa OX=17577...	[more]
sp\|P83606\|BMTI6_RHIMP	1.030e-17	62.07	Kunitz-type serine protease inhibitor 6 (Fragment)...	[more]
sp\|B2G331\|VKT1_HETCR	1.177e-16	47.37	TauPI-stichotoxin-Hcr2b OS=Heteractis crispa OX=17...	[more]
sp\|C0HK74\|VKT3_HETMG	1.352e-16	60.78	Kunitz-type serine protease inhibitor HMGS2 OS=Het...	[more]
sp\|P0DN09\|VKT5_ANEVI	1.828e-16	46.48	U-actitoxin-Avd3h OS=Anemonia viridis OX=51769 PE=...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
C1IBY4	2.337e-19	49.33	Tabserpin OS=Tabanus yao OX=485572 PE=2 SV=1	[more]
C8YJ95	5.643e-19	49.33	Serine protease inhibitor 3 OS=Tabanus yao OX=4855...	[more]
C8YJ94	8.532e-19	48.00	Serine protease inhibitor 2 OS=Tabanus yao OX=4855...	[more]
C8YJ97	3.547e-18	49.33	Serine protease inhibitor 5 OS=Tabanus yao OX=4855...	[more]
C8YJ96	1.031e-16	46.67	Serine protease inhibitor 4 OS=Tabanus yao OX=4855...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000015806.2	6.005e-13	58.33	tissue factor pathway inhibitor-like [Source:NCBI ...	[more]
paplnb	1.265e-12	50.00	papilin-like [Source:NCBI gene;Acc:103035042]	[more]
paplnb	1.772e-12	50.00	papilin-like [Source:NCBI gene;Acc:103035042]	[more]
wfikkn2b	1.924e-12	46.88	WAP, Kazal, immunoglobulin, Kunitz and NTR domain-...	[more]
lrp11	2.207e-11	41.51	LDL receptor related protein 11 [Source:NCBI gene;...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tfpi2	1.887e-15	51.61	tissue factor pathway inhibitor 2 [Source:ZFIN;Acc...	[more]
ENSPMAT00000005038.1	4.608e-10	52.27	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
ENSPMAT00000005043.1	5.262e-10	52.27	pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g...	[more]
WFIKKN1	2.658e-9	35.00	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]
ENSPMAT00000008261.1	5.316e-8	39.22	pep scaffold:Pmarinus_7.0:GL478901:735:1448:1 gene...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO29819	6.504e-18	59.62	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41696	3.617e-15	53.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO26263	3.617e-15	53.85	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO38284	1.925e-14	51.92	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41922	3.827e-13	43.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000012975.2	5.266e-12	50.00	pep primary_assembly:ASM223467v1:12:15740273:15760...	[more]
spint1a	7.367e-12	40.24	kunitz-type protease inhibitor 1 [Source:NCBI gene...	[more]
spint1a	6.786e-11	41.18	serine peptidase inhibitor, Kunitz type 1 [Source:...	[more]
spint1a	7.365e-11	41.18	serine peptidase inhibitor, Kunitz type 1 [Source:...	[more]
wfikkn2a	1.245e-10	43.75	WAP, follistatin/kazal, immunoglobulin, kunitz and...	[more]

BLAST of Kunitz-type serine protease inhibitor BmKTT-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000037994.1	6.557e-52	100.00	SMESG000037994.1	[more]
SMESG000037995.1	2.833e-27	62.50	SMESG000037995.1	[more]
SMESG000037999.1	3.194e-27	62.50	SMESG000037999.1	[more]
SMESG000037999.1	3.298e-27	62.50	SMESG000037999.1	[more]
SMESG000038052.1	3.483e-27	54.67	SMESG000038052.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30026393 ID=SMED30026393|Name=Kunitz-type serine protease inhibitor BmKTT-2|organism=Schmidtea mediterranea sexual|type=transcript|length=419bp
AATCATCTGCGAGTTCACTTAATAATTATAAAATATTTGATTACAAATTA
ACTATAAAATATAATTCAATCCAAATTTTTATAATCAAACCAAAAATGAA
TTCAATTGTAATATTCACTTTGATTTTTTGTGTAATCTTTAGTTTGGGAG
AAAGTCGAGCACCCGAATGTAACGAACCAAAGAAGACAGGAATGTGCGCT
GCTTATTTTCCAAGATTTTATTTCAATATTCAATCGGGAAATTGTGAATC
ATTTATTTATGGTGGATGCCAAGCTAATGGAAACAATTTTAACACAATTG
AAGAGTGTGAAGCTCGTTGTTTGGAATAGTTACAAACTTTTGAAATTTCA
AAAATAAAATAATAAACAACTATGAGTTTATTTTATAAAAAGATATTTCA
AAATAAAGCGAAATTAATT

protein sequence of SMED30026393-orf-1

>SMED30026393-orf-1 ID=SMED30026393-orf-1|Name=SMED30026393-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=109bp
SSASSLNNYKIFDYKLTIKYNSIQIFIIKPKMNSIVIFTLIFCVIFSLGE
SRAPECNEPKKTGMCAAYFPRFYFNIQSGNCESFIYGGCQANGNNFNTIE
ECEARCLE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005576	extracellular region
GO:0033644	host cell membrane

Vocabulary: **biological process**
Term	Definition
GO:0010466	negative regulation of peptidase activity
GO:0044562	envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism
GO:0006508	proteolysis
GO:0010951	negative regulation of endopeptidase activity

Vocabulary: **molecular function**
Term	Definition
GO:0030414	peptidase inhibitor activity
GO:0090729	toxin activity
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0008233	peptidase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000067	goblet cell
PLANA:0000240	body wall musculature
PLANA:0000419	prepharyngeal region
PLANA:0000421	tail
PLANA:0002075	pigment cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036880	Kunitz_BPTI_sf
IPR002223	Kunitz_BPTI
IPR020901	Prtase_inh_Kunz-CS

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 108..108
None	No IPR available	PANTHER	PTHR10083	KUNITZ-TYPE PROTEASE INHIBITOR-RELATED	coord: 53..106
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PRINTS	PR00759	BASICPTASE	coord: 91..106 score: 45.48 coord: 53..67 score: 30.21 coord: 81..91 score: 55.77
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	SMART	SM00131	KU_2	coord: 54..107 e-value: 1.0E-21 score: 88.2
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PFAM	PF00014	Kunitz_BPTI	coord: 56..106 e-value: 9.4E-18 score: 64.2
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	PROSITE	PS50279	BPTI_KUNITZ_2	coord: 56..106 score: 15.129
IPR002223	Pancreatic trypsin inhibitor Kunitz domain	CDD	cd00109	KU	coord: 56..107 e-value: 1.53994E-21 score: 78.4458
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	GENE3D	G3DSA:4.10.410.10		coord: 52..108 e-value: 9.0E-22 score: 78.6
IPR036880	Pancreatic trypsin inhibitor Kunitz domain superfamily	SUPERFAMILY	SSF57362	BPTI-like	coord: 51..107
IPR020901	Proteinase inhibitor I2, Kunitz, conserved site	PROSITE	PS00280	BPTI_KUNITZ_1	coord: 84..102

Main menu

Kunitz-type serine protease inhibitor BmKTT-2

Zeng et. al., 2018

▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

blazegraph-runner