Phospholipid-transporting ATPase

Query:  178 SSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLF----------------------HITRDLE----LYDDK---------VDKRCQVRATNITED-----LGQIQYIFCDKTGTLTENLMEFKRATIGF-----IDFYDDATESALTSDSQPISVLAKMLKK------------------------CHRNIEI---DENL------DISIIEEFVLALAVCNTTMV-SENKNESKIVVEI----PVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS--------RQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET---VLDNI-------------EKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKS 3639
            + N+LKTTKY +L+F+P NLFEQF R AN+YF+ +  LNF P +++F    A  P+LF+L +TA +D  ED  R +SD ++NH+ CL+++ + + Y   +W++I  GDFV++  NE  PADIL+  SS+  G C+IETANLDGE NLK+RQ++    +      P++FT S I  E PN ++ +F G  +  DN K   L K NL+LRGC LRNT  V GIVIYAG+ETK+LLNN+   +KRSKLE+Q+N DV+WC+ +L+ + +  ++GH +W+  +    ++ +   S+ +  +        F T +I+ Q +IP+ LYV+IE+VK  Q++                      +IT DL     ++ DK         V +RC V     + D     L + Q    ++   +       +R +IG      +     +T+S   + S+  +  A ML K                        C +++ +    E+L      ++S + +F +AL +CNT +V S ++  +K+ V      PVK+   F      +   +  +   S   N S   +    P  P S             L  LE        ++ S G   Q  +  S+L +   ++ +           YE+ESPDE AL   A      L++R    V + +  H      + L    FDS RKRMSV++  P T  I +Y KGAD+V++ L+   +S        +++  K    + +Y+  GLRTL +AKR LS++++  W       E +L  SE  L      LE ++ LLGATGIEDRLQ+ VPE +  LR+AG+ IWVLTGDK ETA+NIAY+ KL + ++E+ TL   +QE    +LD               EK   K+S +  +    S    +     L+++G++++  L++++  K FL LA  C+SV+CCRSTP +K+ +V +V+  L+  TLAIGDGANDV+MIQ A VG+GI G+EGMQAVMASDFA+ KF+YL RLL++HGH CY +LA M LY FYK+++ V + FWFQ   GFS S MIDQ   I FNL  + LPPL+ G+ D+D  + VL  NPQ+YKSG +++ YRPR FW N+ D+ +QSLV F + YL Y  + + +  +G    T  L+    ++ +E++ W+  +W++C  S+L+ +F    + N+ C         NPY  +   +  P  YL   +    AL PR+  +S
Sbjct:   60 ADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFT-SVIECEKPNNDLSRFRG-CIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPRGGSVSQRGSIGSHQSVRVVHRTQSTKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTKVRVRFELKSPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSSHKLGSSFPSTPSSD----------GMLLRLEERLGQPTSAIASNGYSSQADNWASELAQEQESEREL---------RYEAESPDEAALVYAARAYNCVLVERLHDQVSV-ELPHLGRLTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDK-FLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLL-FFTVALIYNASCATCYP--PSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRS 1294          

Query:  178 SSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLF----------------------HITRDLE----LYDDK---------VDKRCQVRATNITED-----LGQIQYIFCDKTGTLTENLMEFKRATIGF-----IDFYDDATESALTSDSQPISVLAKMLKK------------------------CHRNIEI---DENL------DISIIEEFVLALAVCNTTMV-SENKNESKIVVEI----PVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS--------RQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET---VLDNI-------------EKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKS 3639
            + N+LKTTKY +L+F+P NLFEQF R AN+YF+ +  LNF P +++F    A  P+LF+L +TA +D  ED  R +SD ++NH+ CL+++ + + Y   +W++I  GDFV++  NE  PADIL+  SS+  G C+IETANLDGE NLK+RQ++    +      P++FT S I  E PN ++ +F G  +  DN K   L K NL+LRGC LRNT  V GIVIYAG+ETK+LLNN+   +KRSKLE+Q+N DV+WC+ +L+ + +  ++GH +W+  +    ++ +   S+ +  +        F T +I+ Q +IP+ LYV+IE+VK  Q++                      +IT DL     ++ DK         V +RC V     + D     L + Q    ++   +       +R +IG      +     +T+S   + S+  +  A ML K                        C +++ +    E+L      ++S + +F +AL +CNT +V S ++  +K+ V      PVK+   F      +   +  +   S   N S   +    P  P S             L  LE        ++ S G   Q  +  S+L +   ++ +           YE+ESPDE AL   A      L++R    V + +  H      + L    FDS RKRMSV++  P T  I +Y KGAD+V++ L+   +S        +++  K    + +Y+  GLRTL +AKR LS++++  W       E +L  SE  L      LE ++ LLGATGIEDRLQ+ VPE +  LR+AG+ IWVLTGDK ETA+NIAY+ KL + ++E+ TL   +QE    +LD               EK   K+S +  +    S    +     L+++G++++  L++++  K FL LA  C+SV+CCRSTP +K+ +V +V+  L+  TLAIGDGANDV+MIQ A VG+GI G+EGMQAVMASDFA+ KF+YL RLL++HGH CY +LA M LY FYK+++ V + FWFQ   GFS S MIDQ   I FNL  + LPPL+ G+ D+D  + VL  NPQ+YKSG +++ YRPR FW N+ D+ +QSLV F + YL Y  + + +  +G    T  L+    ++ +E++ W+  +W++C  S+L+ +F    + N+ C         NPY  +   +  P  YL   +    AL PR+  +S
Sbjct:   60 ADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFT-SVIECEKPNNDLSRFRG-CIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPRGGSVSQRGSIGSHQSVRVVHRTQSTKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTKVRVRFELKSPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSSHKLGSSFPSTPSSD----------GMLLRLEERLGQPTSAIASNGYSSQADNWASELAQEQESEREL---------RYEAESPDEAALVYAARAYNCVLVERLHDQVSV-ELPHLGRLTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDK-FLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLL-FFTVALIYNASCATCYP--PSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRS 1294          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS----------RQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET-------VLDNIEKFC------RKISKQQLANSDTSKYNNTLY-EYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLP----------WRQRK 3717
            YE+ESPDE AL   A      L+ R P  V + +           LC   FDS RKRMSV++  P TG I +Y KGAD+VI+ L+               R++  +  ++++LY+++GLRTL +AK+ +SE+ F  W +  R  E +L   +  L+   Q LE  + LLGATGIEDRLQE VP+ + TLR+AGI +WVLTGDK ETA+NIA+S +L N+   ++T+   NQET        L+ +++F       RK+   +L +   S  +  +  E GL+++GKT++ I  +  + K FL L  +C+SV+CCRSTP +K+ IV +V+  L+V TL+IGDGANDV+MIQ A +GIGI G+EGMQAVM+SDFAIT+FK+L++LLLVHGH CY +LARM +Y  YK+   V + FW+Q   GFS S MID    I FNL  T LPPL+ G+ DKD  +  L   P++YKSG + + Y    FW ++VD+ +QSL+ F++ YL Y+G+++ +  FG   NT  L     +  +E + W++FH +  +GS L+ +F    L N+ CV+   CN+  NPY V+   +  P  YLV  L   +AL PR    S   T   S++ +A +++  LP          WR R+
Sbjct:  689 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTV-RLPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIF-QGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLM-YFLVSLLYNATCVI---CNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKA-QKIDKLPPDKRNLEIQSWRSRQ 1325          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATI 1338
             N++KT+KY +L+F+P N+FEQ  RFAN+YF+ +  LNF P +++F  E + +PI  +L +TA+KD  EDLRR++SD+ +N+  CL+Y+   Q Y    W+D+  GDF+++  NE +PADIL+  SS+ +G C++ETA+LDGE NLKQR ++    ++E +  P  F  + I+ E PN  + KF G     D  ++      +L+LRGC +RNT+   GIVIYAG+ETK++LNN+   +KRSK+E+++N D+ +CIGILI++C+  ++GH IW   F           +   L + +L GF +F T +IL Q +IP+ LYV+IELVKL Q+F ++ DL+LYD++ D   Q RA NI EDLGQIQYIF DKTGTLTEN M F+R TI
Sbjct:   40 GNQIKTSKYTVLSFVPKNIFEQLHRFANLYFVGIAVLNFIPVVNAFQPEVSMIPICVILAVTAIKDAWEDLRRYKSDKVINNRECLIYSRKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNT-IVCEKPNNHLNKFKGYMEHPDQTRT-GFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPS-ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTI 422          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS----------RQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET-------VLDNIEKFC------RKISKQQLANSDTSKYNNTLY-EYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLP----------WRQRK 3717
            YE+ESPDE AL   A      L+ R P  V + +           LC   FDS RKRMSV++  P TG I +Y KGAD+VI+ L+               R++  +  ++++LY+++GLRTL +AK+ +SE+ F  W +  R  E +L   +  L+   Q LE  + LLGATGIEDRLQE VP+ + TLR+AGI +WVLTGDK ETA+NIA+S +L N+   ++T+   NQET        L+ +++F       RK+   +L +   S  +  +  E GL+++GKT++ I  +  + K FL L  +C+SV+CCRSTP +K+ IV +V+  L+V TL+IGDGANDV+MIQ A +GIGI G+EGMQAVM+SDFAIT+FK+L++LLLVHGH CY +LARM +Y  YK+   V + FW+Q   GFS S MID    I FNL  T LPPL+ G+ DKD  +  L   P++YKSG + + Y    FW ++VD+ +QSL+ F++ YL Y+G+++ +  FG   NT  L     +  +E + W++FH +  +GS L+ +F    L N+ CV+   CN+  NPY V+   +  P  YLV  L   +AL PR    S   T   S++ +A +++  LP          WR R+
Sbjct:  717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTV-RLPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIF-QGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLM-YFLVSLLYNATCVI---CNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKA-QKIDKLPPDKRNLEIQSWRSRQ 1353          

Query:  109 ESRTIYP--SVYH-DVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATI 1338
            + R ++P  S++H D + +S    +   N+  TTKY + TF+P NLFEQF R+AN+YF+ +V LN+ P +  F +E   LP+  VLF+  +KDG+ED +R + D+ +N     +Y    Q Y    W+D+  GDF+++  NE +PADIL+  SS+ +G C++ETA+LDGE NLKQR ++    ++E +  P  F  + I+ E PN  + KF G     D  ++      +L+LRGC +RNT+   GIVIYAG+ETK++LNN+   +KRSK+E+++N D+ +CIGILI++C+  ++GH IW   F           +   L + +L GF +F T +IL Q +IP+ LYV+IELVKL Q+F ++ DL+LYD++ D   Q RA NI EDLGQIQYIF DKTGTLTEN M F+R TI
Sbjct:   44 QQRVVFPNNSIFHQDWEEVSR---RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNT-IVCEKPNNHLNKFKGYMEHPDQTRT-GFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPS-ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTI 450          

Query: 1474 IEEFVLALAVCNTTMVSE-NKNESKI----VVEIPVKS---SASFFN--STHSTKTNTL-SNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCI-WKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS-------RQMI--DKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQE-------TVLDNIEKFCRKISKQQLANSDTSKY---NNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCN-TDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEA 3678
            I +F +ALA+CNT +VS  N+   KI    +  +P+KS     S F   S   + + +L S +  S+G   +      +   + P+    +E   +       E+ +  S+ +  +E                N      P +       YE+ESPDE AL   A      L  R P  V + +       F+L  L + PFDS RKRMSV++  P +  + +Y KGAD+VI+ L+S  +        +QMI  +K  ++++ Y+K GLRTL +AK+ +S+ ++ EW     + E ++   E  LL     LE  + LLGATGIEDRLQE VPE +E L KAGI IW+LTGDK ETA+NIAY+ KL   + ++F L   +++       T+L  ++K  + + +Q   + D  +     ++    GLI+ GKT+   L E +  K FL L S C++VVCCR+TP +K+ +V +V+ +LQV TLAIGDGANDV+MIQ A +GIG+ G+EGMQAVMASDFA+++FK+L +LLLVHGH CY +L+ M LY FYK+   V + FW+Q   GFSG+ M D    I FNL  T  PP+I G+ +KD  +  L + P++Y+SG   ++Y P  FW  ++D+ +QSLV F++ Y  YQG++  +  FG   NT+ L +   ++++ES+  +  H L  +GS+L ++F    +  ++CV    CN   NPY ++   M  P  YLV  L T+IAL PR + +    +  PS +  A
Sbjct:  584 IIDFFIALAICNTVVVSAPNQPRQKIRHPSLGGLPIKSLEEIKSLFQRWSVRRSSSPSLNSGKEPSSGVPNAFVSRLPLFSRMKPASPVEEEVSQV------CESPQCSSSSACCTE-----TEKQHGDAGLLNGKAESLPGQPLACNLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGPLTFQL--LHILPFDSVRKRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMSTILKELQKKTQALPEQVSLSEDLLQPPVPRDSGLRAGLIITGKTLEFALQESL-QKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQGSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSIL-SYFLFAIVFGAMCVT---CNPPSNPYWIMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQGSLFPSPILRA 1332          

Query:  115 RTIYPSVYHDVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPIS 1404
            R + P +    D    F     +N+++TTKY +L F+P NLFEQF R AN+YF+ +V LN+ P + +F KE   LP++ VL + A+KDG+ED R+++ D+++N++   +Y+   + Y    W+D+  GDF+++S NE IPAD+++  S++  G C+IET+ LDGE NLKQRQ++    +++  + P  F+ S I  ESPN ++ +F G ++   N + + L K NL+LRGC +RNT+ V GIV+YAG+ETK++LNN+   +KRSKLE++ N DV+WC+ +L+I+C+  ++GH IW+  +  +            +  + L GF +FWT +IL Q +IP+ LYV+IE+VKL Q++ I  D++ Y++K+D   Q RA NI EDLGQIQY+F DKTGTLTEN M F+R ++   D+  +     L S  + +S
Sbjct:   51 RIVVPHIQPFKDEYEKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFS-SRIECESPNNDLSRFRG-FLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMHFFNVPEPDGHIISPL-LAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRLESYQEAVS 477          

Query:  172 KQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTES----HIIVESPNREIYKFNGKWVFEDNAKSIT-----LKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXX-----------XXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIG--------FIDFYDDATE---SALTSDSQPISVLAKMLK-----------KCHRNIEIDENLDISIIE----------EFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTST---GFNLSVFGIQEINPPLP----PSQITIQ-------ETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQG------------------------KCPYKDDV---------------LFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGV--ITLYCKGADNVILPLISKNTS-----RQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVN-HTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPS 3663
            K   N++ TTKY++LTFIP NLFEQ  R AN+YFI +V LN    I +FGK  + LPI FVL +TA+KD  ED RR++SD+++NH  C +++   Q Y    WQ+I  GDFV +S +E IPADIL+ RSS+++G CY+ET NLDGE NLKQRQ I    K      P+ ++ +     I  E P  ++YKF G+    +    +      L K N++LRGC+++NT FVEGIV+YAG +TK++LNNN   +KRS LE+  N D++W +  L+ LC+  ++   +W++ FS              +    +  ++   + S + +  FW+ +I+ Q +IP+ LYV+IE +K+ Q++ +++D  +Y DKVDKR Q RA NITE+LGQIQY+  DKTGTLTEN M F+R ++          +D  D + E   S L SD QP     +M             +  R+  ++  L  S+++           F L +A+CNT +V+   +      E  +       NS  + +   +S RR S+   GF   +  ++E +P       P  IT +       E    P+ +K  ET  ++  +++ +E    +KS S  K N YN  +                         K P++  V               L  FY+SESPDE AL + A + GI+LL+R    V ++  +   + +   L   PFD++RKRMSVI+ +  +G+  I +  KGAD  ++P++S+  S      ++I K  E++  Y+K GLRTL ++ +  +E+++  W  +    E ++   ET L       E+D+ LLG T IEDRLQ+ VPEC+ +LR+AGI +WVLTGDK+ETA+NIAYS +LF+ + ++  +  N    V D + +  ++I++    ++D +        +GL+L   T+S  LD   + + F+ L   C+SV+CCR+TP +KA +V++ K +L+ + LAIGDGANDV+MIQ A VGIG+ G+EGMQAVM+SDFA+ +F++L  LLLVHGH  Y +LA+  LY FYK++++V V FW+Q+ NGFS  V ID +  +++NL  T +PPL+ G  D+D  + +L   P++Y+ G   K YR   FW N++D++WQSLV+F++ Y  Y+G+ + M  FG L  T L+IV   ++ L  ++W+   + S   S+L+ +   +     +       N  +P  +V+  +    + ++ + +   + L PR ++ + + T  PS
Sbjct:  102 KYCGNRISTTKYSVLTFIPKNLFEQLHRAANLYFIFIVILNMI--IGAFGKYISVLPIAFVLGITAIKDAFEDYRRYKSDQKINHSTCRVWDASQQRYRKLEWQNILVGDFVHLSHDEIIPADILLLRSSDVNGVCYVETCNLDGESNLKQRQAIRSMGKYHNANVPLEYSPAEFNYRIACEQPTTDVYKFEGRLEAIEGGPPLAREFTILAKENVLLRGCVVKNTDFVEGIVLYAGKDTKAMLNNNGPRYKRSSLEKMTNVDILWSVCTLLALCVIGAVLSGVWLRTFSTPYIVPFLVFIHPNSSYHNNNDSQYKYSPSYESWFSFWSYIIVLQVMIPISLYVSIEFIKIFQVWFMSQDRNMYYDKVDKRLQCRALNITEELGQIQYVMSDKTGTLTENQMVFRRCSVNGNDYGGRPVVDAVDSSLELVASTLRSD-QPTEKKLQMAALAEAAAKTRRLRPSRDPALESQLASSVLKLGADIDDPVFAFFLTMAICNTVVVNAKPH------EDLMDPDGDIVNSRFAPEE--VSPRRGSSLEDGFKY-LADVEEESPASTQASTPVMITEENDGFEEIELIEFPE-VKTDETQMTEKEETISAE-VAAKKSGSDEKDNNYNGERKEGKGFGILHRPSILSVPFAKLKGMKSPFRRSVDKRSSSSTETAVAPPLHSFYDSESPDELALVEAAREYGIRLLRRRFDDVIVYLRHSTSSVKYKVLHTLPFDADRKRMSVIIRE-SSGLKRIIVLTKGADATVIPVLSEAFSTSARGEEVIFKSQEHLTQYAKEGLRTLCLSMKIWTEEEYQGWKEKHEEAELDMMDKETMLAESTLRAEQDLELLGVTAIEDRLQDGVPECIHSLREAGIRVWVLTGDKIETAVNIAYSSRLFSPSMDLLNIGANGVRAVSDLLTEHLKRIARAYEVSADAAD------SFGLVLNASTMSYCLDPHNLER-FVKLLRGCRSVLCCRATPLQKAQLVNLAKNHLKGKVLAIGDGANDVSMIQGADVGIGLSGQEGMQAVMSSDFAMARFRFLSNLLLVHGHWNYYRLAQTILYFFYKNAMLVFVIFWYQIFNGFSAQVPIDPVYLMVYNLIFTSVPPLLFGCLDQDASAELLLDCPRLYEQGRLGKRYRWYSFWINMLDAVWQSLVVFFICYFTYRGSNVDMWTFGHLLVTQLIIVNTFHLALFVQYWTWPMFWSMFLSVLLFFICALLYNGFVTANWTWTNVKDPPSMVSLKSFSSLEFWMALIISVVLCLTPRYVLTTVVNTVSPS 1356          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLF-NENQEIFTLTGNNQETV----------------------------LDNIEKFCRKISK-----QQLANSDTSKYNNTLYEYG---LILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCY------QGTEL-SMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVV--IVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPS 3663
            Y+++SPDE ALT  A   G     R P  + I    +++  EL  L +  F+++RKRMSVI+  PD G I LYCKGAD +I+  I  +TS+ M      ++  ++  GLRTL +  + L    F +W++R +     +   E+ + ALY+E+E+D+IL+GAT IED+LQ+ VPE +  L +A I IWVLTGDK ETAINIAYS +L  +E +EI  + G     V                            ++ I +    IS      + +   D        +E G   L++ G +++  L   +  + FL +A  C +V+CCR TP +KA +V +VK N +  TL+IGDGANDV+MI+TAH+G+GI G+EGMQAV+ASD++I +FKYL RLLLVHG   Y ++A+   Y FYK+    L  FW+    G+S   + D +    +NL  T LP L +G  D+D +     R P++Y  G     +  R F  +++  ++ SLVIF++ Y  +       G +L   +       T+L++V    +  ++ +W+        GS LV +F   FLL     V  IV  ++   Y V   TM  P  +  + +V+ + L P ++ +   L + PS
Sbjct:  541 YQAQSPDEHALTSAARNFGYVFRARTPQSITIEVMGNEETHEL--LAILDFNNDRKRMSVIVKGPD-GKIRLYCKGADMMIMQRIHPSTSQIMRTSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEEIEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVVVDGQTDTEVEVQLKDTRNTFEQILALPSPLGGKPRIEIETIHEESEAISSARSMDRNIVTPDLKSAEMAEHESGGVALVINGDSLAFALGPRL-ERTFLEVACMCNAVICCRVTPLQKAQVVDLVKRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYIRMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDHYSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFTTFTALVVVVTGQIAFDTSYWTAISHFVIWGS-LVLYFLVCFLLYEWLPVSWIVKTSSSISYGVAFRTMVTPHFWFSILMVSVVLLLPVMLNRFFWLDTHPS 1172          

Query:  160 NFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXX------XXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRA--TNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFI---DFYDDATESALTSDSQPI------SVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNE 1539
            N   K + N +KT+KYNI+TFIP NLFEQF+R AN YF+ ++ L F P+ISS    +  +P++ VL  +A+KDG +D +R  SDR VN     +  N S   E   W ++  GD +++ +N+ + AD+L+  +SE  G C+IET  LDGE NLK R  I   ++    +  ++  +  II E PN ++ KFNGK ++ ++   +     N++LRGCIL+NT++  G+V++AG +TK ++N+ +  FKR+ L++ +N  ++  +  LI +C+ C+I   +W        T+      V  S      + I+L  F+ F++ +IL  T++P+ LYV++E+++      I  D ++Y +  +K    +A  T + E+LGQ+QY+F DKTGTLT N+M F + TI  I   D YD   E   T+D          S      K   +N+       +  I++F   LA+C+T M   +K +
Sbjct:   66 NAQFKYADNVIKTSKYNIITFIPQNLFEQFQRIANFYFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGRKSYVVRNGSLCEED--WSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMGDDLDGITRFDGEIICEPPNNKLDKFNGKLIWNNHEYGV--NNDNILLRGCILKNTRWCYGVVVFAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWEYQTGRYFTIYLPWDDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGEKSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISYGDIYDHKGEVIETNDKTKSLDFSWNSASEPTFKFFDKNLVDATKRQVPEIDQFWRLLALCHTVMPERDKGQ 538          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLF-NENQEIFTLTGNNQETV----------------------------LDNIEKFCRKISK-----QQLANSDTSKYNNTLYEYG---LILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCY------QGTEL-SMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVV--IVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPS 3663
            Y+++SPDE ALT  A   G     R P  + I    +++  EL  L +  F+++RKRMSVI+  PD G I LYCKGAD +I+  I  +TS+ M      ++  ++  GLRTL +  + L    F +W++R +     +   E+ + ALY+E+E+D+IL+GAT IED+LQ+ VPE +  L +A I IWVLTGDK ETAINIAYS +L  +E +EI  + G     V                            ++ I +    IS      + +   D        +E G   L++ G +++  L   +  + FL +A  C +V+CCR TP +KA +V +VK N +  TL+IGDGANDV+MI+TAH+G+GI G+EGMQAV+ASD++I +FKYL RLLLVHG   Y ++A+   Y FYK+    L  FW+    G+S   + D +    +NL  T LP L +G  D+D +     R P++Y  G     +  R F  +++  ++ SLVIF++ Y  +       G +L   +       T+L++V    +  ++ +W+        GS LV +F   FLL     V  IV  ++   Y V   TM  P  +  + +V+ + L P ++ +   L + PS
Sbjct:  506 YQAQSPDEHALTSAARNFGYVFRARTPQSITIEVMGNEETHEL--LAILDFNNDRKRMSVIVKGPD-GKIRLYCKGADMMIMQRIHPSTSQIMRTSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEEIEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVVVDGQTDTEVEVQLKDTRNTFEQILALPSPLGGKPRIEIETIHEESEAISSARSMDRNIVTPDLKSAEMAEHESGGVALVINGDSLAFALGPRL-ERTFLEVACMCNAVICCRVTPLQKAQVVDLVKRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYIRMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDHYSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFTTFTALVVVVTGQIAFDTSYWTAISHFVIWGS-LVLYFLVCFLLYEWLPVSWIVKTSSSISYGVAFRTMVTPHFWFSILMVSVVLLLPVMLNRFFWLDTHPS 1137          

Query:  160 NFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXX------XXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRA--TNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFI---DFYDDATESALTSDSQPI------SVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNE 1539
            N   K + N +KT+KYNI+TFIP NLFEQF+R AN YF+ ++ L F P+ISS    +  +P++ VL  +A+KDG +D +R  SDR VN     +  N S   E   W ++  GD +++ +N+ + AD+L+  +SE  G C+IET  LDGE NLK R  I   ++    +  ++  +  II E PN ++ KFNGK ++ ++   +     N++LRGCIL+NT++  G+V++AG +TK ++N+ +  FKR+ L++ +N  ++  +  LI +C+ C+I   +W        T+      V  S      + I+L  F+ F++ +IL  T++P+ LYV++E+++      I  D ++Y +  +K    +A  T + E+LGQ+QY+F DKTGTLT N+M F + TI  I   D YD   E   T+D          S      K   +N+       +  I++F   LA+C+T M   +K +
Sbjct:   31 NAQFKYADNVIKTSKYNIITFIPQNLFEQFQRIANFYFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGRKSYVVRNGSLCEED--WSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMGDDLDGITRFDGEIICEPPNNKLDKFNGKLIWNNHEYGV--NNDNILLRGCILKNTRWCYGVVVFAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWEYQTGRYFTIYLPWDDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGEKSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISYGDIYDHKGEVIETNDKTKSLDFSWNSASEPTFKFFDKNLVDATKRQVPEIDQFWRLLALCHTVMPERDKGQ 503          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLF-NENQEIFTLTGNNQETV----------------------------LDNIEKFCRKISK-----QQLANSDTSKYNNTLYEYG---LILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCY------QGTEL-SMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVV--IVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIV 3669
            Y+++SPDE ALT  A   G     R P  + I    +++  EL  L +  F+++RKRMSVI+  PD G I LYCKGAD +I+  I  +TS+ M      ++  ++  GLRTL +  + L    F +W++R +     +   E+ + ALY+E+E+D+IL+GAT IED+LQ+ VPE +  L +A I IWVLTGDK ETAINIAYS +L  +E +EI  + G     V                            ++ I +    IS      + +   D        +E G   L++ G +++  L   +  + FL +A  C +V+CCR TP +KA +V +VK N +  TL+IGDGANDV+MI+TAH+G+GI G+EGMQAV+ASD++I +FKYL RLLLVHG   Y ++A+   Y FYK+    L  FW+    G+S   + D +    +NL  T LP L +G  D+D +     R P++Y  G     +  R F  +++  ++ SLVIF++ Y  +       G +L   +       T+L++V    +  ++ +W+        GS LV +F   FLL     V  IV  ++   Y V   TM  P  +  + +V+ + L P ++ +   L + PS  
Sbjct:  541 YQAQSPDEHALTSAARNFGYVFRARTPQSITIEVMGNEETHEL--LAILDFNNDRKRMSVIVKGPD-GKIRLYCKGADMMIMQRIHPSTSQIMRTSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEEIEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVVVDGQTDTEVEVQLKDTRNTFEQILALPSPLGGKPRIEIETIHEESEAISSARSMDRNIVTPDLKSAEMAEHESGGVALVINGDSLAFALGPRL-ERTFLEVACMCNAVICCRVTPLQKAQVVDLVKRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYIRMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDHYSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFTTFTALVVVVTGQIAFDTSYWTAISHFVIWGS-LVLYFLVCFLLYEWLPVSWIVKTSSSISYGVAFRTMVTPHFWFSILMVSVVLLLPVMLNRFFWLDTHPSFA 1174          

Query:  160 NFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXX------XXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRA--TNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFI---DFYDDATESALTSDSQPI------SVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNE 1539
            N   K + N +KT+KYNI+TFIP NLFEQF+R AN YF+ ++ L F P+ISS    +  +P++ VL  +A+KDG +D +R  SDR VN     +  N S   E   W ++  GD +++ +N+ + AD+L+  +SE  G C+IET  LDGE NLK R  I   ++    +  ++  +  II E PN ++ KFNGK ++  N     +   N++LRGCIL+NT++  G+V++AG +TK ++N+ +  FKR+ L++ +N  ++  +  LI +C+ C+I   +W        T+      V  S      + I+L  F+ F++ +IL  T++P+ LYV++E+++      I  D ++Y +  +K    +A  T + E+LGQ+QY+F DKTGTLT N+M F + TI  I   D YD   E   T+D          S      K   +N+       +  I++F   LA+C+T M   +K +
Sbjct:   66 NAQFKYADNVIKTSKYNIITFIPQNLFEQFQRIANFYFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGRKSYVVRNGSLCEED--WSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMGDDLDGITRFDGEIICEPPNNKLDKFNGKLIW--NNHEYGVNNDNILLRGCILKNTRWCYGVVVFAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWEYQTGRYFTIYLPWDDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGEKSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISYGDIYDHKGEVIETNDKTKSLDFSWNSASEPTFKFFDKNLVDATKRQVPEIDQFWRLLALCHTVMPERDKGQ 538          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLF-NENQEIFTLTGNNQETV----------------------------LDNIEKFCRKISK-----QQLANSDTSKYNNTLYEYG---LILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCY------QGTEL-SMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVV--IVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPS 3663
            Y+++SPDE ALT  A   G     R P  + I    +++  EL  L +  F+++RKRMSVI+  PD G I LYCKGAD +I+  I  +TS+ M      ++  ++  GLRTL +  + L    F +W++R +     +   E+ + ALY+E+E+D+IL+GAT IED+LQ+ VPE +  L +A I IWVLTGDK ETAINIAYS +L  +E +EI  + G     V                            ++ I +    IS      + +   D        +E G   L++ G +++  L   +  + FL +A  C +V+CCR TP +KA +V +VK N +  TL+IGDGANDV+MI+TAH+G+GI G+EGMQAV+ASD++I +FKYL RLLLVHG   Y ++A+   Y FYK+    L  FW+    G+S   + D +    +NL  T LP L +G  D+D +     R P++Y  G     +  R F  +++  ++ SLVIF++ Y  +       G +L   +       T+L++V    +  ++ +W+        GS LV +F   FLL     V  IV  ++   Y V   TM  P  +  + +V+ + L P ++ +   L + PS
Sbjct:  506 YQAQSPDEHALTSAARNFGYVFRARTPQSITIEVMGNEETHEL--LAILDFNNDRKRMSVIVKGPD-GKIRLYCKGADMMIMQRIHPSTSQIMRTSTNTHLADFANIGLRTLCLGYKDLDPAYFSDWDSRVKKASAAMQDRESAVDALYEEIEKDLILIGATAIEDKLQDGVPEAIARLSEANIKIWVLTGDKTETAINIAYSCRLLTDETKEIVVVDGQTDTEVEVQLKDTRNTFEQILALPSPLGGKPRIEIETIHEESEAISSARSMDRNIVTPDLKSAEMAEHESGGVALVINGDSLAFALGPRL-ERTFLEVACMCNAVICCRVTPLQKAQVVDLVKRNKKAVTLSIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSIGQFKYLERLLLVHGRWSYIRMAKFLRYFFYKNFAFTLTNFWYSFFCGYSAQTVFDAVLIACYNLFFTALPVLAMGSLDQDVDDHYSLRYPKLYLPGQFNLFFNMRIFIYSVLHGMFSSLVIFFIPYGAFYNAAAASGKDLDDYSALAFTTFTALVVVVTGQIAFDTSYWTAISHFVIWGS-LVLYFLVCFLLYEWLPVSWIVKTSSSISYGVAFRTMVTPHFWFSILMVSVVLLLPVMLNRFFWLDTHPS 1137          

Query:  160 NFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXX------XXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRA--TNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFI---DFYDDATESALTSDSQPI------SVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNE 1539
            N   K + N +KT+KYNI+TFIP NLFEQF+R AN YF+ ++ L F P+ISS    +  +P++ VL  +A+KDG +D +R  SDR VN     +  N S   E   W ++  GD +++ +N+ + AD+L+  +SE  G C+IET  LDGE NLK R  I   ++    +  ++  +  II E PN ++ KFNGK ++ ++   +     N++LRGCIL+NT++  G+V++AG +TK ++N+ +  FKR+ L++ +N  ++  +  LI +C+ C+I   +W        T+      V  S      + I+L  F+ F++ +IL  T++P+ LYV++E+++      I  D ++Y +  +K    +A  T + E+LGQ+QY+F DKTGTLT N+M F + TI  I   D YD   E   T+D          S      K   +N+       +  I++F   LA+C+T M   +K +
Sbjct:   31 NAQFKYADNVIKTSKYNIITFIPQNLFEQFQRIANFYFLVLMILQFIPQISSISWYSTAVPLVIVLAFSAIKDGYDDAQRHISDRNVNGRKSYVVRNGSLCEED--WSNVKVGDVIRMMSNQFVAADLLLLSTSEPYGVCFIETMELDGETNLKNRAAIACTQEMGDDLDGITRFDGEIICEPPNNKLDKFNGKLIWNNHEYGV--NNDNILLRGCILKNTRWCYGVVVFAGKDTKLMMNSGKTKFKRTSLDRFLNILIVGIVLFLIAMCLICTILCAVWEYQTGRYFTIYLPWDDVVPSPEQRGGRQIALIAFLQFFSYIILLNTVVPISLYVSVEIIRFIHSLWINYDTQMYYENGEKSVPAKAHTTTLNEELGQVQYVFSDKTGTLTRNIMTFNKCTINGISYGDIYDHKGEVIETNDKTKSLDFSWNSASEPTFKFFDKNLVDATKRQVPEIDQFWRLLALCHTVMPERDKGQ 503          

Query: 1888 FYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLI---SKNTSRQMIDKIVENM-ELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLY--EYGLILEGKTISVILD-EDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDC-NTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLG 3732
             YE+ESPDE AL   A      LL R P  + +         E + L V PFDS+RK MS+++    +  I LY KGAD+ I+P++   S N+   ++ +  + + + Y++ GLR L++AKR L+   + +W  R + +E +L   E  L   + +LE ++ LLGATGIEDRLQ+ VPE + +L  AGI++WVLTGDK ETAINIAYS KLF +  E+  LT  +++     I  +   +   +   + T  Y  +L   +  L+++GKT++ ILD +  +   FL L+  C SV+CCRSTP +KA +V +VK  L +RTLAIGDGANDV+MIQ A VG+GI G+EGMQAVMA+DF + +F+YL RLLL HG+ CYD+L+RM LY FYK++  V + FW+Q+  GFSG VM+DQ+  +L+NL  T LPPL +G++DK     +L +NP +YK+G    +YRP DFW  ++D+++QSLVIF++    Y  +++ + EFG     S L     +  +E R W+V H LS V S L +++    + +S+C   ++C    + Y V+         +LV+ L T +A+ PR+++ +  ++  P    + +  LQ+   R R+   +G
Sbjct:  875 LYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDK--TTSTLGYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLS-LGSFYLFAIVYDSVC---MNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVI--LQSKRERSRESPIMG 1489          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATE-----SALTSDSQPI-------SVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVS 1524
             NK++TTKY +L+FIP NL EQF R AN+YFI +V LN+ PEIS+FGKE A +P+LFVL +TAVKD  ED RR  SD+R+N+  C +Y+ +++ Y+   WQ++  GD V +S NE +PADIL+ R+S+  G CYI+T +LDGE NLK+R+++   E+ +    P  F  S +  ++P  ++Y+F+G  +     + + +    L+LR   L+NT ++EGIV+YAG+ETKS+LNN+   +KRS++EQQ+N DVIWC+ IL+ILC+  +IG  +W+  F++                 +++   +FWT +++ Q +IPL LYVTIEL K+ Q+FHI  +++L+D + +K+ + RA NITE+LGQIQ+IF DKTGTLTEN M F+R  +   D+    +E     S   + + P+       S +A++ +  +             I+EF++ LA+CNT +V 
Sbjct:  252 GNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFV-SRVEADAPTTKLYRFHGALI-HPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLTA----NMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQR------IQEFLVVLAICNTVIVG 699          

Query: 1888 FYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLI---SKNTSRQMIDKIVENM-ELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLY--EYGLILEGKTISVILD-EDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDC-NTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLG 3732
             YE+ESPDE AL   A      LL R P  + +         E + L V PFDS+RK MS+++    +  I LY KGAD+ I+P++   S N+   ++ +  + + + Y++ GLR L++AKR L+   + +W  R + +E +L   E  L   + +LE ++ LLGATGIEDRLQ+ VPE + +L  AGI++WVLTGDK ETAINIAYS KLF +  E+  LT  +++     I  +   +   +   + T  Y  +L   +  L+++GKT++ ILD +  +   FL L+  C SV+CCRSTP +KA +V +VK  L +RTLAIGDGANDV+MIQ A VG+GI G+EGMQAVMA+DF + +F+YL RLLL HG+ CYD+L+RM LY FYK++  V + FW+Q+  GFSG VM+DQ+  +L+NL  T LPPL +G++DK     +L +NP +YK+G    +YRP DFW  ++D+++QSLVIF++    Y  +++ + EFG     S L     +  +E R W+V H LS V S L +++    + +S+C   ++C    + Y V+         +LV+ L T +A+ PR+++ +  ++  P    + +  LQ+   R R+   +G
Sbjct:  875 LYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDK--TTSTLGYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLS-LGSFYLFAIVYDSVC---MNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVI--LQSKRERSRESPIMG 1489          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATE-----SALTSDSQPI-------SVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVS 1524
             NK++TTKY +L+FIP NL EQF R AN+YFI +V LN+ PEIS+FGKE A +P+LFVL +TAVKD  ED RR  SD+R+N+  C +Y+ +++ Y+   WQ++  GD V +S NE +PADIL+ R+S+  G CYI+T +LDGE NLK+R+++   E+ +    P  F  S +  ++P  ++Y+F+G  +     + + +    L+LR   L+NT ++EGIV+YAG+ETKS+LNN+   +KRS++EQQ+N DVIWC+ IL+ILC+  +IG  +W+  F++                 +++   +FWT +++ Q +IPL LYVTIEL K+ Q+FHI  +++L+D + +K+ + RA NITE+LGQIQ+IF DKTGTLTEN M F+R  +   D+    +E     S   + + P+       S +A++ +  +             I+EF++ LA+CNT +V 
Sbjct:  252 GNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFV-SRVEADAPTTKLYRFHGALI-HPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLTA----NMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQR------IQEFLVVLAICNTVIVG 699          

Query: 1888 FYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLI---SKNTSRQMIDKIVENM-ELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLY--EYGLILEGKTISVILD-EDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDC-NTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLG 3732
             YE+ESPDE AL   A      LL R P  + +         E + L V PFDS+RK MS+++    +  I LY KGAD+ I+P++   S N+   ++ +  + + + Y++ GLR L++AKR L+   + +W  R + +E +L   E  L   + +LE ++ LLGATGIEDRLQ+ VPE + +L  AGI++WVLTGDK ETAINIAYS KLF +  E+  LT  +++     I  +   +   +   + T  Y  +L   +  L+++GKT++ ILD +  +   FL L+  C SV+CCRSTP +KA +V +VK  L +RTLAIGDGANDV+MIQ A VG+GI G+EGMQAVMA+DF + +F+YL RLLL HG+ CYD+L+RM LY FYK++  V + FW+Q+  GFSG VM+DQ+  +L+NL  T LPPL +G++DK     +L +NP +YK+G    +YRP DFW  ++D+++QSLVIF++    Y  +++ + EFG     S L     +  +E R W+V H LS V S L +++    + +S+C   ++C    + Y V+         +LV+ L T +A+ PR+++ +  ++  P    + +  LQ+   R R+   +G
Sbjct:  875 LYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDK--TTSTLGYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLS-LGSFYLFAIVYDSVC---MNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVI--LQSKRERSRESPIMG 1489          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATE-----SALTSDSQPI-------SVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVS 1524
             NK++TTKY +L+FIP NL EQF R AN+YFI +V LN+ PEIS+FGKE A +P+LFVL +TAVKD  ED RR  SD+R+N+  C +Y+ +++ Y+   WQ++  GD V +S NE +PADIL+ R+S+  G CYI+T +LDGE NLK+R+++   E+ +    P  F  S +  ++P  ++Y+F+G  +     + + +    L+LR   L+NT ++EGIV+YAG+ETKS+LNN+   +KRS++EQQ+N DVIWC+ IL+ILC+  +IG  +W+  F++                 +++   +FWT +++ Q +IPL LYVTIEL K+ Q+FHI  +++L+D + +K+ + RA NITE+LGQIQ+IF DKTGTLTEN M F+R  +   D+    +E     S   + + P+       S +A++ +  +             I+EF++ LA+CNT +V 
Sbjct:  252 GNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFV-SRVEADAPTTKLYRFHGALI-HPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLTA----NMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQR------IQEFLVVLAICNTVIVG 699          

Query: 1888 FYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLI---SKNTSRQMIDKIVENM-ELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLY--EYGLILEGKTISVILD-EDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDC-NTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRP 3660
             YE+ESPDE AL   A      LL R P  + +         E + L V PFDS+RK MS+++    +  I LY KGAD+ I+P++   S N+   ++ +  + + + Y++ GLR L++AKR L+   + +W  R + +E +L   E  L   + +LE ++ LLGATGIEDRLQ+ VPE + +L  AGI++WVLTGDK ETAINIAYS KLF +  E+  LT  +++     I  +   +   +   + T  Y  +L   +  L+++GKT++ ILD +  +   FL L+  C SV+CCRSTP +KA +V +VK  L +RTLAIGDGANDV+MIQ A VG+GI G+EGMQAVMA+DF + +F+YL RLLL HG+ CYD+L+RM LY FYK++  V + FW+Q+  GFSG VM+DQ+  +L+NL  T LPPL +G++DK     +L +NP +YK+G    +YRP DFW  ++D+++QSLVIF++    Y  +++ + EFG     S L     +  +E R W+V H LS V S L +++    + +S+C   ++C    + Y V+         +LV+ L T +A+ PR+++ +  ++  P
Sbjct:  875 LYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMENDK--TTSTLGYGQSLRKKQRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLS-LGSFYLFAIVYDSVC---MNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCP 1467          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATE-----SALTSDSQPI-------SVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVS 1524
             NK++TTKY +L+FIP NL EQF R AN+YFI +V LN+ PEIS+FGKE A +P+LFVL +TAVKD  ED RR  SD+R+N+  C +Y+ +++ Y+   WQ++  GD V +S NE +PADIL+ R+S+  G CYI+T +LDGE NLK+R+++   E+ +    P  F  S +  ++P  ++Y+F+G  +     + + +    L+LR   L+NT ++EGIV+YAG+ETKS+LNN+   +KRS++EQQ+N DVIWC+ IL+ILC+  +IG  +W+  F++                 +++   +FWT +++ Q +IPL LYVTIEL K+ Q+FHI  +++L+D + +K+ + RA NITE+LGQIQ+IF DKTGTLTEN M F+R  +   D+    +E     S   + + P+       S +A++ +  +             I+EF++ LA+CNT +V 
Sbjct:  252 GNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFV-SRVEADAPTTKLYRFHGALI-HPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFPVPYLPPNKLTA----NMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQR------IQEFLVVLAICNTVIVG 699          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCY-------QGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLL 3495
            Y + SPDE AL + A + G     R P +V I     +K +E+  L V  F S+RKRMS+I+  P+   I L+CKGAD VI   ++    +   ++ + ++E ++ +GLRTL +A   +    + EW+  F      L   E++L      +E ++ LLGAT IEDRLQ+ VPE + +L  AGI IWVLTGDK ETAINI YS +L + + +I  L   N+E++    E   R   + +   S ++K  N      L+++G T+   L  D+    F  L   C+ V+CCR +P +KA +V MV  +    TLAIGDGANDV MIQ A+VGIGI G EG+QA  ASD++I +F+YL+RLLLVHG   Y +++++ LY FYK+  + ++  WF V +G+SG ++ ++ +  L+N+  T +PP  +G+++K   +  + R P +YK+  + K +  + FW  I +++  S+ +FWL    Y        G        G L  T +++       L +  W+    L+  GS +V WF   FLL
Sbjct:  478 YHAASPDERALVEGAQKFGYIFDTRTPKYVEINALGVRKRYEV--LNVLEFTSSRKRMSLIVRTPENK-IKLFCKGADTVIYERLAPQ-GQAFREQTLRHLEEFASDGLRTLCLAVADIRPDVYQEWSQTFDKASVALQNRESKLEDAANLIENNLRLLGATAIEDRLQDGVPETIASLLDAGIYIWVLTGDKQETAINIGYSCRLISHSMDIIIL---NEESLDATREVIHRHYGEFK---SSSAKDANV----ALVIDGTTLKYALSCDL-RNDFQDLCILCRVVICCRVSPMQKAEVVEMVTQSTNAVTLAIGDGANDVAMIQKANVGIGISGVEGLQAACASDYSIAQFRYLQRLLLVHGAWNYARISKLILYSFYKNVCLYVIELWFAVYSGWSGQILFERWTIGLYNVLFTAMPPFAMGLFEKFCTAETMIRYPMLYKTSQNAKLFNVKVFWIWIFNALLHSVFLFWLPLAAYTKEVIWSDGKTSDYLLMGNLVYTYVIVTVCLKAGLITNSWTWLTHLAIWGS-IVLWFG--FLL 1001          

Query:  172 KQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITP-MSFTESHIIVESPNREIYKFNGKWVFEDNAK-SITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATI-GFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNESKI 1548
            K  +N++ T KY+ ++F+P  LFEQF+R++N +F+ +  L   PE+S  G+ T  +P++F+L ++A+K+ +ED++R ++D  +NH    +   DS ++    W ++  GD +K+  N   PAD+++  SSE    C+IETANLDGE NLK RQ +  P   E   T  +   E  I  E PNR +Y+FNG  V  +  K    L    ++ RG ILRNT +V GIV+Y+G ETK + N+     KRS +++  N  ++    ILI LCI   + ++ W ++     +   +     + K  SL G+ L  T  IL+  +IP+ L VT+ELV+  Q   I  D+E+Y ++ +     R +N+ E+LG ++YIF DKTGTLT+N+MEFK+ +I G++      T      +SQ +           +NI +  +   ++IEEF+  L+VC+T +    +N + I
Sbjct:   45 KYGNNRITTAKYSFISFLPAFLFEQFRRYSNCFFLLIAILQQIPEVSPTGRYTTLVPLMFILSVSAIKEIIEDIKRHRADNEINHRS--IERLDSGSWCTVRWSELTVGDIIKVGINTFFPADLILLSSSEPQAMCFIETANLDGETNLKIRQAL--PATAELLETKDLQRLEGRIECELPNRHLYEFNG--VLRETGKPPAALGNDQVLQRGAILRNTAWVFGIVVYSGQETKLMKNSTSAPLKRSTVDKLTNTQILMLFMILISLCIISGLCNLFWTRE----HSETDWYLGLTDFKTKSL-GYNLL-TFFILYNNLIPISLQVTLELVRFLQAIFINYDIEMYHEESNTPAMARTSNLNEELGMVKYIFSDKTGTLTQNVMEFKKCSIAGYV-----YTAERTPEESQLV-----------QNI-LGRHETSAVIEEFLELLSVCHTVIPERKENGNMI 477          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLE--------------------------LYDDK---------VDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFI----DFYDDATESALTSDSQPISV---LAKMLKKCHRNIEIDENLDISIIEE---------------------FVLALAVCNTTMVSENKNESKIVVE-----------------IPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLIS-----KNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSA---SETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQ-------ETVLDNIEKFCRKISKQQLANSDTSKYNNTLYE--YGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCN-TDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLP 3702
             N +KT KY + +F+P+NLFEQF R ANIYF+ +  LNF P +++F  E A +PI  +L LTAVKDG ED RR+Q+D+++N+MPC ++      +    W+D+  GDFVK+ +NE IPADIL+  +S+ +G C++ETANLDGE NLKQR+++           P +F +S ++ E+PN  +  F G ++   + +       +L+LRGC +RNT    GIV+YAG+ETKS+LNNN   +KRSK+E+++N DV++C+ +L  +C+  ++GH IW++ FS + + +    +   + + +L GF +F+T +IL Q +IP+ LYV+IELVK+ Q+F IT+D E                          ++ DK         V KRC +  T    +    +    +  G   E +  +++  +  +    +  DD T     +++Q  +     +K+      ++     L+  ++ +                     F LALA+CNT +VS    + + V                     + S   FF+S    +     NR T        F I E  P          +TF+I        ++     K + SEG                 ++      ++V    YE+ SPDE AL   A   G  +++R P +V + K  ++   + + L V  FDS R+RMS+I+  P T  I +Y KGAD+ ++  +      ++ ++++  +  +++++Y+++GLRTL  AK+ +SE++F  W   F   ++ LSA    E  L+    ++E ++ LLGATGIEDRLQE VPE ++ LR+AG+ +WVLTGDK ETA+NIAYS KL +    +FT T N +       E  L  + +    +          S +   L E   GL+++G T+++ L ED+V + F+ L  HC++V+CCR TP +K+++V +++  L+V TLA+GDGANDVNMIQ A VGIG+ G+EGMQAVMASDFAIT+FK+L+RLLLVHGH CY +LA M +Y FYK+   V + FW+Q   GFSG+ MID    I FNL  T  PP++ GI DK+     L   P++Y+ G H + YR   FW  I+D+ +QSLV F++ Y  Y  +++ +  FG   NT  L     ++ +E + W+V HW+  VGS+LV +F      +++C   + CN   +PY +++  M  P  YLV  L T +AL PR  ++    T  PS+   A R+L+ LP
Sbjct:   48 GNAIKTNKYRLWSFLPMNLFEQFHRLANIYFVGLAILNFIPVVNAFQPEVALIPICIILALTAVKDGWEDFRRYQTDQQLNNMPCFIFRRRLMCFVERRWKDVRVGDFVKVLSNEIIPADILLLHTSDPNGVCHMETANLDGETNLKQRKVVPGFSTLGEPFQPQTF-DSTVVCENPNNNLNLFKG-FIERPDKRRSGFGIDSLLLRGCTVRNTDDAAGIVVYAGHETKSMLNNNGPRYKRSKIERKMNTDVLFCVLLLFFMCLIGALGHAIWLETFSTMPSYIVPDSNGNYISS-ALAGFYMFFTMIILLQVMIPVSLYVSIELVKMGQIFFITQDAELYDQELDSRVQCRALNITEDLGQIQYVFSDKTGTLTENKMVFKRCTIMGTEYCHEENAARLAVINGGGNEEEEVTIYQKTKLPPLFPLEELQDDHTGHKNHANTQVAAASRRRSKVAAGAQSDMAFSSPLETVVVPDRKLMLEVDHQMASIQTGPYLDFFLALAICNTVVVSTLTAQRQRVKGRRNSSYSGSSSHNMGQWFKISSLQKFFSSMRFKR-----NRETMA----DPFAIDEDEP----------DTFHISS-----VSDSRPGQKVISSEGK----------------DKRSLSRSEEVC---YEAHSPDEAALIHAAKAYGFTMVERTPRYVTV-KLPNETLLKFEVLDVLTFDSTRRRMSIIVRHPHTNEIIMYTKGADSAVMEKLGNVFSVESAAKRIAVRTQKDLDMYARDGLRTLCFAKKVISEQEFKAW---FTSRQEALSAIDEKEERLMETANDIENNLTLLGATGIEDRLQENVPETIQALRRAGMQVWVLTGDKPETAVNIAYSCKLLDHEDLVFTFTTNKKSVCKMRLEDTLSEVRRTWGGLGLDPQFRGYNSTFTGPLMEPSIGLVIDGPTLNMALSEDLVEQ-FVELCKHCRAVLCCRVTPLQKSSVVKVIRQKLRVMTLAVGDGANDVNMIQAADVGIGVSGQEGMQAVMASDFAITRFKHLQRLLLVHGHWCYSRLANMVIYFFYKNVAYVNLLFWYQFFCGFSGTAMIDYWLMIFFNLFFTSAPPIMFGIMDKEVSDSTLLSLPELYRRGQHSEGYRRSTFWIAILDAFYQSLVCFFIPYWTYNDSDIGIFSFGTPMNTVSLFTIILHLAIEIKSWTVVHWVIMVGSVLV-YFILTLAYSAIC---ISCNPPSDPYWIMHKQMADPMFYLVCVLTTVVALLPRYTLRVLKGTLAPSLHLRA-RQLERLP 1263          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLE--------------------------LYDDK---------VDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFI----DFYDDATESALTSDSQPISV---LAKMLKKCHRNIEIDENLDISIIEE---------------------FVLALAVCNTTMVSENKNESKIVVE-----------------IPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLIS-----KNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSA---SETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQ-------ETVLDNIEKFCRKISKQQLANSDTSKYNNTLYE--YGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCN-TDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLP 3702
             N +KT KY + +F+P+NLFEQF R ANIYF+ +  LNF P +++F  E A +PI  +L LTAVKDG ED RR+Q+D+++N+MPC ++      +    W+D+  GDFVK+ +NE IPADIL+  +S+ +G C++ETANLDGE NLKQR+++           P +F +S ++ E+PN  +  F G ++   + +       +L+LRGC +RNT    GIV+YAG+ETKS+LNNN   +KRSK+E+++N DV++C+ +L  +C+  ++GH IW++ FS + + +    +   + + +L GF +F+T +IL Q +IP+ LYV+IELVK+ Q+F IT+D E                          ++ DK         V KRC +  T    +    +    +  G   E +  +++  +  +    +  DD T     +++Q  +     +K+      ++     L+  ++ +                     F LALA+CNT +VS    + + V                     + S   FF+S    +     NR T        F I E  P          +TF+I        ++     K + SEG                 ++      ++V    YE+ SPDE AL   A   G  +++R P +V + K  ++   + + L V  FDS R+RMS+I+  P T  I +Y KGAD+ ++  +      ++ ++++  +  +++++Y+++GLRTL  AK+ +SE++F  W   F   ++ LSA    E  L+    ++E ++ LLGATGIEDRLQE VPE ++ LR+AG+ +WVLTGDK ETA+NIAYS KL +    +FT T N +       E  L  + +    +          S +   L E   GL+++G T+++ L ED+V + F+ L  HC++V+CCR TP +K+++V +++  L+V TLA+GDGANDVNMIQ A VGIG+ G+EGMQAVMASDFAIT+FK+L+RLLLVHGH CY +LA M +Y FYK+   V + FW+Q   GFSG+ MID    I FNL  T  PP++ GI DK+     L   P++Y+ G H + YR   FW  I+D+ +QSLV F++ Y  Y  +++ +  FG   NT  L     ++ +E + W+V HW+  VGS+LV +F      +++C   + CN   +PY +++  M  P  YLV  L T +AL PR  ++    T  PS+   A R+L+ LP
Sbjct:   48 GNAIKTNKYRLWSFLPMNLFEQFHRLANIYFVGLAILNFIPVVNAFQPEVALIPICIILALTAVKDGWEDFRRYQTDQQLNNMPCFIFRRRLMCFVERRWKDVRVGDFVKVLSNEIIPADILLLHTSDPNGVCHMETANLDGETNLKQRKVVPGFSTLGEPFQPQTF-DSTVVCENPNNNLNLFKG-FIERPDKRRSGFGIDSLLLRGCTVRNTDDAAGIVVYAGHETKSMLNNNGPRYKRSKIERKMNTDVLFCVLLLFFMCLIGALGHAIWLETFSTMPSYIVPDSNGNYISS-ALAGFYMFFTMIILLQVMIPVSLYVSIELVKMGQIFFITQDAELYDQELDSRVQCRALNITEDLGQIQYVFSDKTGTLTENKMVFKRCTIMGTEYCHEENAARLAVINGGGNEEEEVTIYQKTKLPPLFPLEELQDDHTGHKNHANTQVAAASRRRSKVAAGAQSDMAFSSPLETVVVPDRKLMLEVDHQMASIQTGPYLDFFLALAICNTVVVSTLTAQRQRVKGRRNSSYSGSSSHNMGQWFKISSLQKFFSSMRFKR-----NRETMA----DPFAIDEDEP----------DTFHISS-----VSDSRPGQKVISSEGK----------------DKRSLSRSEEVC---YEAHSPDEAALIHAAKAYGFTMVERTPRYVTV-KLPNETLLKFEVLDVLTFDSTRRRMSIIVRHPHTNEIIMYTKGADSAVMEKLGNVFSVESAAKRIAVRTQKDLDMYARDGLRTLCFAKKVISEQEFKAW---FTSRQEALSAIDEKEERLMETANDIENNLTLLGATGIEDRLQENVPETIQALRRAGMQVWVLTGDKPETAVNIAYSCKLLDHEDLVFTFTTNKKSVCKMRLEDTLSEVRRTWGGLGLDPQFRGYNSTFTGPLMEPSIGLVIDGPTLNMALSEDLVEQ-FVELCKHCRAVLCCRVTPLQKSSVVKVIRQKLRVMTLAVGDGANDVNMIQAADVGIGVSGQEGMQAVMASDFAITRFKHLQRLLLVHGHWCYSRLANMVIYFFYKNVAYVNLLFWYQFFCGFSGTAMIDYWLMIFFNLFFTSAPPIMFGIMDKEVSDSTLLSLPELYRRGQHSEGYRRSTFWIAILDAFYQSLVCFFIPYWTYNDSDIGIFSFGTPMNTVSLFTIILHLAIEIKSWTVVHWVIMVGSVLV-YFILTLAYSAIC---ISCNPPSDPYWIMHKQMADPMFYLVCVLTTVVALLPRYTLRVLKGTLAPSLHLRA-RQLERLP 1263          

Query:  115 RTIYPSVYHDVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLF----------------------HITRDLE----LYDDKVD---------KRCQVRATNITE-----DLGQIQYIFC---DKTGTLTENL---------MEFKRATIGF--------------------IDFYDDATESALTSDSQ---PISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSA--------------SFFNSTHSTKTNT-----LSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESES-----PDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISK---NTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLV----AWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKRVDEESSNTIFDYLKFNAN-KSKEEC 3825
            R I PS   D + L       S NK++TTKY  L+FIP NLFEQ  RFAN+YF+ +  LNF P +++F  E + +PI+FV+ +TA+KD  ED RR +SD++VN+  C +Y+   Q Y    W ++C GD V++  NE IPAD+++  SS+ +G C+IETANLDGE NLKQRQ++ D  ++     P +F+ S I  E+PN ++ +F G ++       + L   NL+LR C +RNT+ V GIV+YAG+ETK++ NN+   +KRSKLE+++N DV+W + +L+++C   +IGH +W+ +  +   ++  +       + +L  F +FWT +I+ Q +IP+ LYV+IE+VKL Q++                      +IT DL     L+ DK           +RC V  T          L Q +   C   D++ TL             +   R+++                         +    E A+  D Q    +S L+  ++   R     +  +IS+I +F LAL VCNT +VS + ++ + VV++PV  +               S     HS  TNT     L+ +  + G + S F       P+ P +  ++           L    SD+  ++I+       +      ++           +       E        PDE AL + A   G  LL R P  V +          +  L V PF S RKRMSV++  P TG + +Y KGADNVI+ L  +   + SR++++    +++ Y++ GLRTL VAK+ L E+++  W  R    E ++   E  LL   + LE D+ LLGATGI DRLQEEVPE +E L++AGI +WVLTGDK ETAINIA++ KL      I     +++E     +++   ++  QQ+  +D  +  + + +  L+++G+T+   L +++   AFL L   C+SV+CCRSTP +K+ +V +V+  L+V TLAIGDGANDV+MIQ A VG+GI G+EGMQAVM+SDFAI++FK+LR+L+LVHGH CY +LA M LY FYK+ + V + FW+Q   GFSGS M +    I FNL  T +PPL+ G+ DKD  +  L + P +YKSG + ++Y P  FW NI+D+ +QSLV F++ Y  Y G+++ +  F    N S L++   + ++ESR  +  H      SLL+     ++A + L +  CV    CN+  NPY +    M +P  YLV  L T +AL PR++ ++   T  PS + +A ++++ L   Q   + L   + NK     SS  +   L  NA+  S  EC
Sbjct:   48 RVILPSWTED-EQLKELQQSYSKNKVRTTKYTFLSFIPKNLFEQLHRFANVYFVFLSALNFVPIVNAFQPEISIIPIIFVMSITAIKDLWEDQRRRKSDQQVNNRFCDVYDRKQQRYVERRWAEVCVGDLVRLCCNEIIPADMVLLHSSDSNGVCHIETANLDGETNLKQRQVVRDLTQQGAEFVPENFS-SRIECENPNNDLRRFRG-FMEHPGKVRVGLHSENLLLRSCTVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNLDVLWSVALLLLMCFIAAIGHGLWLSELEDPIFMIPDNT------HPALAAFYMFWTMIIVLQVLIPISLYVSIEIVKLGQIYFIQNDLDLYNPVLDTGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVAGTEYPHHENAVSLEQYEDQACGDVDRSLTLRSRTSKKSLSCKSLSCNRSSVSLNTLTAESDTHSVHDTLCRHTTGAFSSTMECAVVPDPQLHMKLSTLSSPMRSPLR----PDAAEISLILDFFLALTVCNTVVVS-SPSQPRHVVQMPVVRTPLRSLEEMKAMFQKLSLPRFPHSPNTNTDTPPSLTKKLFARGRSASYFPNSNPQTPVTPLESPVK-----------LSGTPSDTPPALITPALSSSGAWGEDAEDKKQAKDNAADESESDDEDEEEELLYEAESPDEAALVQAAKAYGCTLLGRSPEQVLVAVP-GTGPLSISLLHVLPFHSARKRMSVVVRHPLTGEVVVYTKGADNVIMELAKQAEDDFSREVMELTQRHLDQYAREGLRTLCVAKKVLGEQEYEAWMKRHEYAETSIENREELLLESAERLETDLTLLGATGIVDRLQEEVPETIEALQEAGIKVWVLTGDKQETAINIAFACKLLRPTDHILMANCDSKEACEARLQEL--QLEVQQVTKADEPE-GDCISDCVLVIDGRTLDYALQKEL-QGAFLDLTCCCRSVICCRSTPLQKSQVVRLVRDKLEVMTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMSSDFAISRFKFLRKLILVHGHWCYARLANMILYFFYKNVMYVNLLFWYQFFCGFSGSTMTNSWVLIFFNLLFTSVPPLVYGVLDKDVSAETLLKLPDLYKSGQNSQAYLPTTFWLNILDAFYQSLVCFFIPYFAYAGSDIGVFSFASPINGSALLIILLHQVIESRTLTWIH-----ASLLIFSGLFYYAFVLLFSITCVT---CNSPTNPYGIETKMMSEPLYYLVCVLTTVLALLPRMLSRAFSNTICPSDLVKA-QKIERLS-AQDYSSSLQKWKENKATQRVSSRPVPQNLSVNADIPSLTEC 1352          

Query:  184 NKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLF----------------------HITRDLE----LYDDKVD---------KRCQVRATNITE-----DLGQIQYIFC---DKTGTLTENL---------MEFKRATIGF--------------------IDFYDDATESALTSDSQ---PISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSA--------------SFFNSTHSTKTNT-----LSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESES-----PDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISK---NTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLV----AWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKRVDEESSNTIFDYLKFNAN-KSKEEC 3825
            N ++TTKY +++FIP+NLF+QF R AN+YF+ +V LN+ P + +F KE   +P+  VL + A KD +ED RR++ D+++N+    +Y+   Q Y    W ++C GD V++  NE IPAD+++  SS+ +G C+IETANLDGE NLKQRQ++ D  ++     P +F+ S I  E+PN ++ +F G ++       + L   NL+LR C +RNT+ V GIV+YAG+ETK++ NN+   +KRSKLE+++N DV+W + +L+++C   +IGH +W+ +  +   ++  +       + +L  F +FWT +I+ Q +IP+ LYV+IE+VKL Q++                      +IT DL     L+ DK           +RC V  T          L Q +   C   D++ TL             +   R+++                         +    E A+  D Q    +S L+  ++   R     +  +IS+I +F LAL VCNT +VS + ++ + VV++PV  +               S     HS  TNT     L+ +  + G + S F       P+ P +  ++           L    SD+  ++I+       +      ++           +       E        PDE AL + A   G  LL R P  V +          +  L V PF S RKRMSV++  P TG + +Y KGADNVI+ L  +   + SR++++    +++ Y++ GLRTL VAK+ L E+++  W  R    E ++   E  LL   + LE D+ LLGATGI DRLQEEVPE +E L++AGI +WVLTGDK ETAINIA++ KL      I     +++E     +++   ++  QQ+  +D  +  + + +  L+++G+T+   L +++   AFL L   C+SV+CCRSTP +K+ +V +V+  L+V TLAIGDGANDV+MIQ A VG+GI G+EGMQAVM+SDFAI++FK+LR+L+LVHGH CY +LA M LY FYK+ + V + FW+Q   GFSGS M +    I FNL  T +PPL+ G+ DKD  +  L + P +YKSG + ++Y P  FW NI+D+ +QSLV F++ Y  Y G+++ +  F    N S L++   + ++ESR  +  H      SLL+     ++A + L +  CV    CN+  NPY +    M +P  YLV  L T +AL PR++ ++   T  PS + +A ++++ L   Q   + L   + NK     SS  +   L  NA+  S  EC
Sbjct:   74 NSIRTTKYTLISFIPMNLFQQFHRAANLYFLFLVLLNWVPAVEAFQKEITMIPLAVVLTVIAFKDAMEDYRRYRYDKKINNTLTHVYSGKQQRYVERRWAEVCVGDLVRLCCNEIIPADMVLLHSSDSNGVCHIETANLDGETNLKQRQVVRDLTQQGAEFVPENFS-SRIECENPNNDLRRFRG-FMEHPGKVRVGLHSENLLLRSCTVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNLDVLWSVALLLLMCFIAAIGHGLWLSELEDPIFMIPDNT------HPALAAFYMFWTMIIVLQVLIPISLYVSIEIVKLGQIYFIQNDLDLYNPVLDTGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVAGTEYPHHENAVSLEQYEDQACGDVDRSLTLRSRTSKKSLSCKSLSCNRSSVSLNTLTAESDTHSVHDTLCRHTTGAFSSTMECAVVPDPQLHMKLSTLSSPMRSPLR----PDAAEISLILDFFLALTVCNTVVVS-SPSQPRHVVQMPVVRTPLRSLEEMKAMFQKLSLPRFPHSPNTNTDTPPSLTKKLFARGRSASYFPNSNPQTPVTPLESPVK-----------LSGTPSDTPPALITPALSSSGAWGEDAEDKKQAKDNAADESESDDEDEEEELLYEAESPDEAALVQAAKAYGCTLLGRSPEQVLVAVP-GTGPLSISLLHVLPFHSARKRMSVVVRHPLTGEVVVYTKGADNVIMELAKQAEDDFSREVMELTQRHLDQYAREGLRTLCVAKKVLGEQEYEAWMKRHEYAETSIENREELLLESAERLETDLTLLGATGIVDRLQEEVPETIEALQEAGIKVWVLTGDKQETAINIAFACKLLRPTDHILMANCDSKEACEARLQEL--QLEVQQVTKADEPE-GDCISDCVLVIDGRTLDYALQKEL-QGAFLDLTCCCRSVICCRSTPLQKSQVVRLVRDKLEVMTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMSSDFAISRFKFLRKLILVHGHWCYARLANMILYFFYKNVMYVNLLFWYQFFCGFSGSTMTNSWVLIFFNLLFTSVPPLVYGVLDKDVSAETLLKLPDLYKSGQNSQAYLPTTFWLNILDAFYQSLVCFFIPYFAYAGSDIGVFSFASPINGSALLIILLHQVIESRTLTWIH-----ASLLIFSGLFYYAFVLLFSITCVT---CNSPTNPYGIETKMMSEPLYYLVCVLTTVLALLPRMLSRAFSNTICPSDLVKA-QKIERLS-AQDYSSSLQKWKENKATQRVSSRPVPQNLSVNADIPSLTEC 1356          

Query:  112 SRTIYPSVYHD-VDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLF----------------------HITRDLE----LYDDK---------VDKRCQVRATNITED-----LGQIQYIFCDK------TGTL--------------------------TENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEI----DENL-----DISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNK---SVISEGXXXXXXXXXXXXNRY---NVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQK-AFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNT-------SRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIE--------KF-CRKISKQQLAN------------SDTSKYNNT---LYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRK 3717
            +RT++ ++ +D      N     ++NK+KTTKY +L+F+P NLFEQF RFAN+YF+ +  LNF P +++F  E A  P++F+L +TA+KD  ED RR +SD+ +NHM CL+Y    + Y   YW+++  GDF+++  NE +PAD+L+  +S+    C+IETA LDGE NLKQRQ++      +    P+ +  S I  E PN ++ +F G ++   + +   L K NL+LRGC +RNT+   GIVIYAG+ETK++LNNN   +KRSKLE+Q+N DV WC+ IL+++C+  +IGH +WM  + +   V           +  +    LF T +I+FQ +IP+ L+V+IE+VK+ Q++                      +IT DL     ++ DK         V +RC V     + D     +   Q +  ++       GTL                          T +  E KRA+I        A  S +  D  P   L   + +C   +E      ++L     D+  + +F +AL +CNT +VS      + V    +KS                            V  I++      PS++T         +   L TN+S S+K   S++S  S     + +++  R    N ++ K   +D+   +F E+ESPDE AL   A      L+ R P  V +   +  K +FEL  L    FDS RKRMSV++  P T  IT+Y KGAD+VI+ LI   T        R+++ K    + LY+ +GLRTL +AK+ LS++++  W  R    E  +   E  L      LE ++ LLGATGIEDRLQ+ VPE + +LRKAG+ IWVLTGDK ETAINIAY+ KL +  +EI TL  ++QE     +E        KF C   +  Q A             S TS  ++    ++  GL+++G+T++  LD+ +  K FL +A  C+SV+CCRSTP +K+ +V +V+  L+V TLAIGDGANDV+MIQ A VG+GI G+EGMQAVMASDFA+ +F+YL++LLLVHGH CY +LA M LY FYK+++ V + FW+Q   GFSGS M+DQ   I FNL  +  P LI G  DKD  +  L+  PQ+Y +G + + Y+P  FW N++D+ +QSL+ F++ Y  Y  +++ +  +G    T  L     ++ +E++ W+  +W+S +G  +  +F      N+ C      +  N Y  +   +  P  YL+  +    AL PR   ++C  T  P+ V+   R+L  LP   R+
Sbjct:   30 TRTVHANILYDHTKGGDNPNRHYANNKIKTTKYTLLSFLPKNLFEQFHRFANVYFVFIALLNFVPVVNAFQPELALAPVVFILSVTAIKDLWEDYRRHRSDKEINHMDCLVYCRSEKRYVEKYWKELRVGDFIRLRCNEILPADVLLLSTSDPDRLCHIETATLDGETNLKQRQVVRSFIDLDCEFDPLKYN-SVIECEKPNNDLNRFRG-YIIHRSGRRDGLYKDNLLLRGCTIRNTEEAVGIVIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFSAIGHGLWMFQYGDKRPVFDVLGPEGTELSPVVSAIYLFLTMIIVFQVLIPISLFVSIEIVKICQVYFIHQDLELYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYSHDANARRIAMYQEVESEEEDCTSHGGTLPRRDSVASHQSGKVVLRSQSTKSHRRTGSRAEAKRASILS---KHTAFSSPMEKDITPDPQLMDKVNECSSQMEFMRFHSQSLNQIPPDLCDVFDFFIALTICNTVVVSSPNQPRQKVRRFELKSP---------------------------VKTIEDFIKRFTPSRLTSGSNS---SSSSSLATNRSSSHKLGCSMLSSPSAENTLTKLNEEKRPVPPNFDKSKALAQDECELRF-EAESPDEAALVYAARAYKCALVGRLPDQVTVELPHLGKLSFEL--LHTLGFDSTRKRMSVVVKHPLTEQITVYTKGADSVIMDLIRPATDDCKGKRQRKILYKTQNYLNLYAADGLRTLCIAKKVLSKEEYASWLQRHLEAETAIQRREELLFESALRLETNLQLLGATGIEDRLQDGVPETIASLRKAGLQIWVLTGDKQETAINIAYACKLLDPEEEIITLNADSQEACARLLENSLHYIQAKFLCDPRAGPQAAGDYAGIHFSSPVCSPTSSGHSGPFLVHRLGLVIDGRTLAYALDKSLEDK-FLAVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFRYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMVDQWYLIFFNLMFSAFPQLITGTLDKDVSAETLQELPQLYMNGQNSEEYKPYMFWMNMIDAFYQSLICFFIPYFAYIDSDVDLFTWGTPITTLALFTILLHLGIETKTWTWMNWVS-IGFSMALFFTVALCYNASCPTCF--SPSNTYWTMQRLLGDPLFYLLCVVTPVAALLPRYCYRACQGTLFPNPVHMG-RQLDKLPVEMRR 1308          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF----------------YDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIE-------EFVLALAVCNTTMVSENKNESKIV------VEIP--VKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXN---RYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS---------RQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPR 3624
            +NK+KTTKY   TFIP NLFEQF RFAN+YF+AV  LNF P +++F    A +PI  +L +TA+KD  ED RR++SD+ +N+M CL+YN +S ++    W+D+C GDFVK+  NE IPADIL+   S+ +G C+IETANLDGE NLKQRQ++    K+     P SF  + I+ E PN  + KF G                +L+LRGC +RNT+ V GIV+YAG+ETK++LNN+   +KRSK+E+Q+N +V +C+GIL I+C+  ++G+ IW   F               L + +L GF +F T +IL Q +IP+ LYV+IELVKL Q++ I  DL+LYD+++D   Q RA NITEDLGQIQYIF DKTGTLTEN M F+R TI   +F                  +  E  +T D     +LAK+ +   +   +   +  S I        +F LALA+CNT +VS      + V      V IP  +KSS S        K   L  R     F+ S       + P  P+     +   +P   K   ++ S       S G      S  S  N              +DD     YE+ESPDE AL   A      L+ R P  V + +         D L    FDS RKRMSV++  P T  I +Y KGAD+VI+ L+   +          R+M  +   +++ Y+++GLRTL +AK+ LSE +F  W+N     E  +   E  L+   Q LE ++ LLGATGIEDRLQE VP+ + +LR+AGINIWVLTGDK ETA+NIAYS +L ++    F              EK  R + K+  A   + +      + GL+++G+T++VI    + TK FL L+ HC+SV+CCR+TP +K+ +V +V+  L+V TL+IGDGANDV+MIQ A +GIGI G+EGMQAVM+SDFAI++FK+L++LLLVHGH CY +LA M +Y FYK+   V + FW+Q+  GFSG+ MID    I FNL  T +PPL+ GI DKD  +  L   P +YKSG   KSY+   FW  IVD+ +QSLV F++ Y  YQGT++ +  FG   NT  L     ++ +E + W++ HW++ V S ++ +F      N++CV+   CN   NPY ++   M  P  Y+V  +   IAL PR
Sbjct:   60 TNKIKTTKYTFFTFIPKNLFEQFHRFANVYFVAVAALNFVPVVNAFQPAIAIIPICIILAITAIKDIWEDFRRFKSDKEINYMSCLVYNRNSNDFVEKCWKDVCVGDFVKLLCNEIIPADILLLFCSDQNGICHIETANLDGETNLKQRQVVKGFCKQGMAFDPESFRNT-IVCEKPNNNLNKFKG------------FGNESLLLRGCTVRNTEEVVGIVVYAGHETKAMLNNSGPRYKRSKIERQMNINVFFCVGILFIMCLIGALGYGIWTSKFVIPPLFDVPEADGSYL-SPALAGFYMFLTMIILLQILIPISLYVSIELVKLGQIYLIHSDLDLYDEEIDLSVQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGYEFSHQENGKWQCFSSVSELKNIGEKDVTPDHM---LLAKVREASVKFAAVSPLVSQSNIRAASSPYIDFFLALAICNTVVVSTATEPRQRVSPVMGSVTIPPLLKSSGSSLE-----KFQHLFQRLKLLSFSQSSSTSPSSSDPGTPTSSKNNKVSPVPSADKDNISSSSSGEAECQSSGKDDSSVSKNSADNCLEEMIATVSSLHIEDDFC---YEAESPDEAALVHAARAYSFTLMSRTPDQVTV-RLPQGTLLTFDLLYTLGFDSVRKRMSVVVRHPITREIIVYTKGADSVIMDLLDDPSKANISDEKKLRKMQARTQRHLDWYARDGLRTLCIAKKVLSEDEFERWSNFREEAEAAIENREELLMETAQHLETNLSLLGATGIEDRLQEGVPDTIASLREAGINIWVLTGDKQETAVNIAYSCQLLDQYDTFFP-------------EKKKRGLFKRSKAPV-SHELEAVRPQVGLVIDGRTLNVIFQGGLETK-FLELSRHCRSVLCCRATPLQKSMVVKLVRDKLKVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAISRFKHLKKLLLVHGHWCYTRLANMVIYFFYKNVAYVNLLFWYQLFCGFSGTTMIDYWQMIFFNLFFTSVPPLVFGILDKDISAETLMSLPHLYKSGQQCKSYKMSTFWIAIVDAFYQSLVCFFIPYFTYQGTDIDVLSFGTPINTIALFTILMHLAIEIKTWTILHWVTIVVS-IICYFVVSLAYNAICVL---CNEPANPYWIMEMQMSDPLFYIVCIITPVIALLPR 1206          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRF--ANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIH-----DPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDAT----------------------------ESALTSDSQPISVLAKMLKKCHRNIEIDEN--LDISIIEEFVLALAVCNTTMVS-ENKNESKI----VVEIPVKS----------------SASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVE-----NMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPR 3624
            +N+++TTKY +L FIP NLFEQF R+  AN+YF+ +V LN+ P + +F KE   LP++ VL + A+KDG+ED R+++ D+ +N++   +Y    + Y+ S W+D+  G F+++  +E IPAD+++  SS+  G C+IET++LDGE NLKQRQ++      DPEK   RI            E+P  +I  F G ++   N + I L K NL+LRGCI+RNT+ V GIV+YAG+ETK++LNN+   +KRS+LE+++N D++W + +LI +C+  +IGH +W+  F             ++  + +L GF +FWT +IL Q +IP+ LYV+IE+VKL Q++ I  D E Y +K D   + RA NI EDLGQ+QYIF DKTGTLTEN M F+R +I  +++  +A                             E  +  D + +S   ++  K     E  E+  L+ S I +F LALA+CNT +VS  N+   K+    +V  P+KS                SAS F S     +   SN     G  LS F   ++  P               K++  L+   S ++ + +    L Q +   +          +  Y+ +         SPDE AL   A      L  R P  V +   +         L + PFDS RKRMSVI+  P T  + +Y KGAD+ I+ LI+  TS  M+ K ++     +++ Y+K GLRTL +AK+ +++ ++ EW     + E ++   E  L      LE  + LLGATGIEDRLQE VP+ +E+LRKAGINIW+LTGDK ETA+NIAY+ +L   + ++F L        +D++ K     S QQ         + +   +GL+++G T+ + + E + +K FL L   C++V+CCR+TP +K+ +V +V+ NLQV  LAIGDGANDV+MIQ A +G+GI G+EGMQAVM+SDFA++ FK+LR+LLLVHGH CY +LA M LY FYK+ + V + FW+Q   GFSG+ M D    ILFNL  T +PP+I GI DKD  +  L   P++YKSG   ++YR   FW  I+D+ +QSL  F++ Y  Y G++L +  FG    TS L V   ++L+ES+  +  HW+  +G+ + A+FA      ++C   ++CN   NPY +V + ++ P  YLV  L   IAL PR
Sbjct:   63 NNRIQTTKYTLLNFIPRNLFEQFHRWVAANLYFLFLVFLNWVPLVEAFQKEITMLPLVAVLTIIAIKDGLEDYRKYKLDKVINNIVTQVYCRKEKKYKESCWKDVNVGHFIRLQCDEIIPADMVLLHSSDPDGICHIETSSLDGETNLKQRQVVKGYSMFDPEKFSGRIQ----------CENPTSDISSFKG-FLDHPNKEKIGLSKQNLLLRGCIVRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSRLERRLNTDILWSVLLLIAMCLFGAIGHGLWLAGFPESPIFSIPEPGGQH-TSPALAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQNDSEFYCEKSDSMIECRALNIAEDLGQVQYIFSDKTGTLTENKMVFRRCSIAGMEYSHEANGKVLVYRRCHVPHIQHMHSEWLYVFSCQEKDVVPDPRLLSKFDQINPKSLYMSEEAEDTALETSYIVDFFLALAICNTVVVSLPNQPRQKVRMPSMVRTPMKSLEEIKQMFQRFSVRKLSASSFTSGKDCPSENGSN----FGSKLSFFTRGKLASPTAELA---------DKSINDLQAAGSLNSTAELEPEVLEQSNFVTACDELDKAAACELCYEAE---------SPDEAALVHAARAYNCTLQSRTPDQVTVELGF-IGPLTFQVLHILPFDSVRKRMSVIIRHPLTNKVVVYTKGADSAIMDLIAM-TSEAMVKKNIQMLTQKHLDDYAKGGLRTLCIAKKVMTDSEYAEWLQSHFLAETSIDNREEMLYESAVRLETKLTLLGATGIEDRLQEGVPDTIESLRKAGINIWMLTGDKEETAVNIAYACRLLEHSDKLFNLNE------IDSLGKPNAFSSGQQ---------DKSGLHFGLVIDGGTLEIAMHESLQSK-FLQLTERCRAVICCRATPLQKSKVVKLVRNNLQVMALAIGDGANDVSMIQVADIGVGISGQEGMQAVMSSDFAVSHFKHLRKLLLVHGHWCYTRLANMILYFFYKNLMFVNLLFWYQFFCGFSGTAMTDFWMLILFNLLFTSVPPIIYGILDKDVSAETLTALPELYKSGQTSQAYRSSTFWVTILDAFYQSLACFFIPYFAYIGSDLGIYSFGNFLITSALFVVLLHLLIESKSLTWIHWI-VMGASIAAYFAFSLAFGAVC---INCNPPANPYWIVQNHVRDPAFYLVCLLSIFIALLPR 1218          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIH--------DPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDA---------TESALTSDSQPISVLAKMLKKCHRNIEIDEN--LDISIIEEFVLALAVCNTTMVS-ENKNESKI----VVEIPVKS----------------SASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPP---LPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVE-----NMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPR 3624
            +N+++TTKY +L FIP NLFEQF R AN+YF+ +V LN+ P + +F KE   LP++ VL + A+KDG+ED R+++ D+ +N++   +Y    + Y+ S W+D+  G F+++  +E IPAD+++  SS+  G C+IET++LDGE NLKQRQ++         DPEK   RI            E+P  +I  F G ++   N + I L K NL+LRGCI+RNT+ V GIV+YAG+ETK++LNN+   +KRS+LE+++N D++W + +LI +C+  +IGH +W+  F             ++  + +L GF +FWT +IL Q +IP+ LYV+IE+VKL Q++ I  D E Y +K D   + RA NI EDLGQ+QYIF DKTGTLTEN M F+R +I  +++  +A         TE  +  D + +S   ++  K     E  E+  L+ S I +F LALA+CNT +VS  N+   K+    +V  P+KS                SAS F S     +   SN     G  LS F   ++  P   L    I   +      +   LE    + +  V +   L + ++        + ++    +         +S +PD         Q+ ++L   GP                  L + PFDS RKRMSVI+  P T  + +Y KGAD+ I+ LI+ +    M+ K ++     +++ Y+K GLRTL +AK+ +++ ++ EW     + E ++   E  L      LE  + LLGATGIEDRLQE VP+ +E+LRKAGINIW+LTGDK ETA+NIAY+ +L   + ++F L        +D++ K     S QQ         + +   +GL+++G T+ + + E + +K FL L   C++V+CCR+TP +K+ +V +V+ NLQV  LAIGDGANDV+MIQ A +G+GI G+EGMQAVM+SDFA++ FK+LR+LLLVHGH CY +LA M LY FYK+ + V + FW+Q   GFSG+ M D    ILFNL  T +PP+I GI DKD  +  L   P++YKSG   ++YR   FW  I+D+ +QSL  F++ Y  Y G++L +  FG    TS L V   ++L+ES+  +  HW+  +G+ + A+FA      ++C   ++CN   NPY +V + ++ P  YLV  L   IAL PR
Sbjct:   45 NNRIQTTKYTLLNFIPRNLFEQFHRAANLYFLFLVFLNWVPLVEAFQKEITMLPLVAVLTIIAIKDGLEDYRKYKLDKVINNIVTQVYCRKEKKYKESCWKDVNVGHFIRLQCDEIIPADMVLLHSSDPDGICHIETSSLDGETNLKQRQVVKGYSMDDEFDPEKFSGRIQ----------CENPTSDISSFKG-FLDHPNKEKIGLSKQNLLLRGCIVRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSRLERRLNTDILWSVLLLIAMCLFGAIGHGLWLAGFPESPIFSIPEPGGQH-TSPALAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQNDSEFYCEKSDSMIECRALNIAEDLGQVQYIFSDKTGTLTENKMVFRRCSIAGMEYSHEANGKVLFTKYTEKDVVPDPRLLSKFDQINPKSLYMSEEAEDTALETSYIVDFFLALAICNTVVVSLPNQPRQKVRMPSMVRTPMKSLEEIKQMFQRFSVRKLSASSFTSGKDCPSENGSN----FGSKLSFFTRGKLASPTAELADKSINDLQAAGSLNSTAELEPEVLEQSNFVTACDELDKAAACELCYEAESPDEAALVHAARAYNCTLQSRTPD---------QVTVELGFIGP-------------LTFQVLHILPFDSVRKRMSVIIRHPLTNKVVVYTKGADSAIMDLIT-DAVITMVKKNIQMLTQKHLDDYAKGGLRTLCIAKKVMTDSEYAEWLQSHFLAETSIDNREEMLYESAVRLETKLTLLGATGIEDRLQEGVPDTIESLRKAGINIWMLTGDKEETAVNIAYACRLLEHSDKLFNLNE------IDSLGKPNAFSSGQQ---------DKSGLHFGLVIDGGTLEIAMHESLQSK-FLQLTERCRAVICCRATPLQKSKVVKLVRNNLQVMALAIGDGANDVSMIQVADIGVGISGQEGMQAVMSSDFAVSHFKHLRKLLLVHGHWCYTRLANMILYFFYKNLMFVNLLFWYQFFCGFSGTAMTDFWMLILFNLLFTSVPPIIYGILDKDVSAETLTALPELYKSGQTSQAYRSSTFWVTILDAFYQSLACFFIPYFAYIGSDLGIYSFGNFLITSALFVVLLHLLIESKSLTWIHWI-VMGASIAAYFAFSLAFGAVC---INCNPPANPYWIVQNHVRDPAFYLVCLLSIFIALLPR 1182          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRF--ANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIH--------DPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDAT----------------------------ESALTSDSQPISVLAKMLKKCHRNIEIDEN--LDISIIEEFVLALAVCNTTMVS-ENKNESKI----VVEIPVKS----------------SASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPP---LPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS-----RQMIDKIVENMEL--------YSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIM 3633
            +N+++TTKY +L FIP NLFEQF R+  AN+YF+ +V LN+ P + +F KE   LP++ VL + A+KDG+ED R+++ D+ +N++   +Y    + Y+ S W+D+  G F+++  +E IPAD+++  SS+  G C+IET++LDGE NLKQRQ++         DPEK   RI            E+P  +I  F G ++   N + I L K NL+LRGCI+RNT+ V GIV+YAG+ETK++LNN+   +KRS+LE+++N D++W + +LI +C+  +IGH +W+  F             ++  + +L GF +FWT +IL Q +IP+ LYV+IE+VKL Q++ I  D E Y +K D   + RA NI EDLGQ+QYIF DKTGTLTEN M F+R +I  +++  +A                             E  +  D + +S   ++  K     E  E+  L+ S I +F LALA+CNT +VS  N+   K+    +V  P+KS                SAS F S     +   SN     G  LS F   ++  P   L    I   +      +   LE    + +  V +   L + ++        + ++    +         +S +PD         Q+ ++L   GP                  L + PFDS RKRMSVI+  P T  + +Y KGAD+ I+ LIS   S     R +  K  +N+++        Y+K GLRTL +AK+ +++ ++ EW     + E ++   E  L      LE  + LLGATGIEDRLQE VP+ +E+LRKAGINIW+LTGDK ETA+NIAY+ +L   + ++F L                   SK +  N+  S  +     +GL+++G T+ + + E + +K FL L   C++V+CCR+TP +K+ +V +V+ NLQV  LAIGDGANDV+MIQ A +G+GI G+EGMQAVM+SDFA++ FK+LR+LLLVHGH CY +LA M LY FYK+ + V + FW+Q   GFSG+ M D    ILFNL  T +PP+I GI DKD  +  L   P++YKSG   ++YR   FW  I+D+ +QSL  F++ Y  Y G++L +  FG    TS L V   ++L+ES+  +  HW+  +G+ + A+FA      ++C   ++CN   NPY +V + ++ P  YLV  L   IAL PR ++
Sbjct:   75 NNRIQTTKYTLLNFIPRNLFEQFHRWVAANLYFLFLVFLNWVPLVEAFQKEITMLPLVAVLTIIAIKDGLEDYRKYKLDKVINNIVTQVYCRKEKKYKESCWKDVNVGHFIRLQCDEIIPADMVLLHSSDPDGICHIETSSLDGETNLKQRQVVKGYSMDDEFDPEKFSGRIQ----------CENPTSDISSFKG-FLDHPNKEKIGLSKQNLLLRGCIVRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSRLERRLNTDILWSVLLLIAMCLFGAIGHGLWLAGFPESPIFSIPEPGGQH-TSPALAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQNDSEFYCEKSDSMIECRALNIAEDLGQVQYIFSDKTGTLTENKMVFRRCSIAGMEYSHEANGKVLFTKYTAKYNMKYKRFAMNPNIRYFEKDVVPDPRLLSKFDQINPKSLYMSEEAEDTALETSYIVDFFLALAICNTVVVSLPNQPRQKVRMPSMVRTPMKSLEEIKQMFQRFSVRKLSASSFTSGKDCPSENGSN----FGSKLSFFTRGKLASPTAELADKSINDLQAAGSLNSTAELEPEVLEQSNFVTACDELDKAAACELCYEAESPDEAALVHAARAYNCTLQSRTPD---------QVTVELGFIGP-------------LTFQVLHILPFDSVRKRMSVIIRHPLTNKVVVYTKGADSAIMDLISPYPSCVPAPRPVQKKTDKNIQMLTQKHLDDYAKGGLRTLCIAKKVMTDSEYAEWLQSHFLAETSIDNREEMLYESAVRLETKLTLLGATGIEDRLQEGVPDTIESLRKAGINIWMLTGDKEETAVNIAYACRLLEHSDKLFNL-------------------SKHEKVNAKLSGLH-----FGLVIDGGTLEIAMHESLQSK-FLQLTERCRAVICCRATPLQKSKVVKLVRNNLQVMALAIGDGANDVSMIQVADIGVGISGQEGMQAVMSSDFAVSHFKHLRKLLLVHGHWCYTRLANMILYFFYKNLMFVNLLFWYQFFCGFSGTAMTDFWMLILFNLLFTSVPPIIYGILDKDVSAETLTALPELYKSGQTSQAYRSSTFWVTILDAFYQSLACFFIPYFAYIGSDLGIYSFGNFLITSALFVVLLHLLIESKSLTWIHWI-VMGASIAAYFAFSLAFGAVC---INCNPPANPYWIVQNHVRDPAFYLVCLLSIFIALLPRYVL 1236          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLF----------------------HITRDLE----LYDDK---------VDKRCQVRATNITE----------DLGQIQYIFCDKTGTLTENLM-----------EFKRATIGFIDFYDDATESALTSDSQPISVL-AKMLKKCHRNIEIDENLDISIIE-------EFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET-------VLDNIEKFCRKISKQQLANSDTSKYNNTLY----EYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPR 3624
            +NK+KTTKY   TFIP NLFEQF RFAN+YF+AV  LNF P +++F    A +PI  +L +TA+KD  ED RR++SD+ +N+M CL+YN +S ++    W+D+C GDFVK+  NE IPADIL+   S+ +G C+IETANLDGE NLKQRQ++    K+     P SF  + I+ E PN  + KF G ++  DN +       +L+LRGC +RNT+ V GIV+YAG+ETK++LNN+   +KRSK+E+Q+N +V +C+GIL I+C+  ++G+ IW   F               L + +L GF +F T +IL Q +IP+ LYV+IELVKL Q++                      +IT DL     ++ DK         V +RC +     +            + +++ I        T+ L             F++ + G  D    A  S +  D  P  +L AK+ +   +   +   +  S I        +F LALA+CNT +VS      + V   PV  S      T   K ++ S++R    +NLS       + P  P+           KN K   + K DS  SV    +       I+ ++  ++    C          YE+ESPDE AL   A      L+ R P  V + +         D L    FDS RKRMSV++  P T  I +Y KGAD+VI+ L+   +                                 +F  W+N     E  +   E  L+   Q LE ++ LLGATGIEDRLQE VP+ + +LR+AGINIWVLTGDK ETA+NIAYS +L ++   +FT+   ++ET        L++++KF  +  K+ L     +  ++ L     + GL+++G+T++VI    + TK FL L+ HC+SV+CCR+TP +K+ +V +V+  L+V TL+IGDGANDV+MIQ A +GIGI G+EGMQAVM+SDFAI++FK+L++LLLVHGH CY +LA M +Y FYK+   V + FW+Q+  GFSG+ MID    I FNL  T +PPL+ GI DKD  +  L   P +YKSG   KSY+   FW  IVD+ +QSLV F++ Y  YQGT++ +  FG   NT  L     ++ +E + W++ HW++ V S ++ +F      N++CV+   CN   NPY ++   M  P  Y+V  +   IAL PR
Sbjct:   41 TNKIKTTKYTFFTFIPKNLFEQFHRFANVYFVAVAALNFVPVVNAFQPAIAIIPICIILAITAIKDIWEDFRRFKSDKEINYMSCLVYNRNSNDFVEKCWKDVCVGDFVKLLCNEIIPADILLLFCSDQNGICHIETANLDGETNLKQRQVVKGFCKQGMAFDPESFRNT-IVCEKPNNNLNKFKG-YMQLDNGQRTGFGNESLLLRGCTVRNTEEVVGIVVYAGHETKAMLNNSGPRYKRSKIERQMNINVFFCVGILFIMCLIGALGYGIWTSKFVIPPLFDVPEADGSYL-SPALAGFYMFLTMIILLQILIPISLYVSIELVKLGQIYLIHSDLDLYDEEIDLSVQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGYEFSHQENGKWQCFSSVSELKNIGSTVRHKGTKALRRCHSARPNIQGHFRKKSEGRFDISQVAFSSPIEKDVTPDHMLLAKVREASVKFAAVSPLVSQSNIRAASSPYIDFFLALAICNTVVVSTATEPRQRVS--PVMGSVY---KTILLKQSSNSDKRID--WNLSSSTSPSSSDPGTPTS---------SKNNK--SSGKDDS--SVSKNSADNCLEEMIATVSSLHIEDDFC----------YEAESPDEAALVHAARAYSFTLMSRTPDQVTV-RLPQGTLLTFDLLYTLGFDSVRKRMSVVVRHPITREIIVYTKGADSVIMDLLDDPSK-------------------------GNHTCNDEFERWSNFREEAEAAIENREELLMETAQHLETNLSLLGATGIEDRLQEGVPDTIASLREAGINIWVLTGDKQETAVNIAYSCQLLDQYDTVFTINTESKETCESILDCTLEDVKKFFPEKKKRGLFKRSKAPVSHELEAVRPQVGLVIDGRTLNVIFQGGLETK-FLELSRHCRSVLCCRATPLQKSMVVKLVRDKLKVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAISRFKHLKKLLLVHGHWCYTRLANMVIYFFYKNVAYVNLLFWYQLFCGFSGTTMIDYWQMIFFNLFFTSVPPLVFGILDKDISAETLMSLPHLYKSGQQCKSYKMSTFWIAIVDAFYQSLVCFFIPYFTYQGTDIDVLSFGTPINTIALFTILMHLAIEIKTWTILHWVTIVVS-IICYFVVSLAYNAICVL---CNEPANPYWIMEMQMSDPLFYIVCIITPVIALLPR 1200          

Query:  178 SSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLE--------------------------LYDDK---------VDKRCQVRATNITEDLGQ---IQYIFCD--------KTGTL--------------------------TENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLD---------ISIIEEFVLALAVCNTTMV-SENKNESKIVVEIPVKSSAS--------FFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKF---YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLI---SKNTSRQMIDKIVEN-----MELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET---VLDNIEKFCR-KISKQQLANSDT-----------SKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKS 3639
            + N+LKTTKY +L+F+P NLFEQF R AN+YF+ +  LNF P +++F    A  P+LF+L +TA+KD  ED  R +SD  +NH+ CL+++ + + Y   YW++I  GDFV++  NE IPADIL+  SS+  G C+IETANLDGE NLK+RQ++    +      P++FT S I  E PN ++ +F G ++   N +   L K NL+LRGC +RNT+ V GIVIYAG+ETK+LLNN+   +KRS+LE+Q+N DV+WC+ +L+ + +  ++GH +W++ +     +     S+ +  + +      F+T +I+ Q +IP+ LYV+IE+VK+ Q++ I +D+E                          ++ DK         V +RC V     + D       +Y   D        K GT+                          T +  E KRA++        A  S +  D  P   L + + +C R + I  + +         +S + +F +AL +CNT +V S ++   K+ V   +KS           F  S  ++  +++ N  TS   + S          LP        + +    L  LE     +  S+ S G   Q     S  +    +Q KCP +     +    YE+ESPDE AL   A      L+ R    V + +  H      + L    FDS RKRMSV++  P T  I +Y KGAD+V++ L+   S + +R    K + +     + LY+  GLRTL +AKR LS++++  W       E ++ + E  L      LE ++ LLGATGIEDRLQE VPE +  LR+AG+ IWVLTGDK ETAINIAY+ KL +  +E+ TL  ++QE    +LD    + + +  +  L NS++           S   +      L+++G++++  L++ +  K FL LA  C+SV+CCRSTP +K+ +V +V+  L+  TLAIGDGANDV+MIQ A VG+GI G+EGMQAVMASDFA+ +F+YL RLL+VHGH CY +LA M LY FYK+++ V + FWFQ   GFS S MIDQ   I FNL  + LP L+ G+ DKD  + +L R PQ+YKSG +++ YRPR FW N+VD+ +QSLV F++ YL Y  +++ +  +G       L     ++ +E++ W+  +WL+C  S  + +F+   + N+ C         NPY  +   +  P  YL   +    AL PR+  K+
Sbjct:   64 ADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSREEKKYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFT-SVIECEKPNNDLSRFRG-YIMHSNGEKAGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLARYQEADSEEEEVVSKVGTISHRGSTGSHQSIWMTHKTQSIKSHRRTGSRAEAKRASM---LSKHTAFSSPMEKDITPDPKLLEKVSECDRFLAIARHQEHPLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRQKVRVRFELKSPVKTIEDFLRRFTPSRLASGCSSIGNLSTSKSSHKSGSAF------LP--------SLSQDSMLLGLEEKLGQTAPSIASNGYASQAGQEESWASECTTDQ-KCPGEQREQQEGELRYEAESPDEAALVYAARAYNCALVDRLHDQVSV-ELPHLGRLTFELLHTLGFDSIRKRMSVVIRHPLTDEINVYTKGADSVVMDLLLPCSSDDARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAEASVESREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSQEACAALLDQCLSYVQSRNPRSTLQNSESNLSVGFSFNPVSTSTDASPSPSLVIDGRSLAYALEKSLEDK-FLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVDVFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFL-FFSVALIYNTSCATCYP--PSNPYWTMQTLLGDPLFYLTCLIAPIAALLPRLFFKA 1308          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMID----------KIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET-------VLDNIEKF------CRKISKQQLANSDTSKYNNTLY-EYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKR 3753
            YE+ESPDE AL   A      L+ R P  V + +         D L    FDS RKRMSV++  P T  I +Y KGAD+VI+ L+        ID          +  ++++LY+++GLRTL +AK+ + E+ F  W +  R  E +L   E  L+   Q LE  + LLGATGIEDRLQE VP+ +  LR+AGI +WVLTGDK ETA+NIAYS KL ++   ++++   NQET        L++I++F       RK+   ++     S  +  +  E GL+++GKT++ I    +  K FL L  +C+SV+CCRSTP +K+ IV +V+  L V TL+IGDGANDV+MIQ A +GIGI G+EGMQAVM+SDFAI +F +L++LLLVHGH CY +LARM +Y FYK+   V + FW+Q   GFSGS MID    I FNL  T LPP+I G+ DKD  +  L   P++YKSG + + Y    FW ++ D+ +QSL+ F++ YL Y+G+++ +  FG   NT  L     +  +E + W+V H L  +GS L+ +F    + N+ CV    CN+  NPY V+   +  P  YL+  L   +AL PR  + S   T   S++ +A +++  LP  +R + ++ N  S +R
Sbjct:  687 YEAESPDEAALVHAARAYSFTLVSRTPEQVTV-RLPQGICLTFDLLFTLGFDSVRKRMSVVVRHPLTDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKRFHEPQQPARKLCGHRIPPKMPSVNSGAMAPEIGLVIDGKTLNAIFQGKLENK-FLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLM-YFVVSLIYNATCVT---CNSPTNPYWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKA-QKIDKLPIDKR-NLEIQNWRSKQR 1324          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATI 1338
             N++KT+KY +L+FIP NLFEQ  RFAN+YF+ +V LNF P +++F    + +P+  +L +TA+KD  ED RR++SD+ +N+   L+Y+   Q Y +  WQD+  GDFV++  NE +PADIL+  SS+ SG C++ETANLDGE NLKQR+++    + E +  P  F  S I+ E PN  + KF G     D  ++      +L+LRGC +RNT+   GIVIYAG+ETK++LNN+   +KRSK+E++IN D+ +CIG+L ++C+  ++GH +W   F               L +++L GF +F T +IL Q +IP+ LYV+IELVKL Q+F +  DL+LYD++ D   Q RA NITEDLGQIQYIF DKTGTLTEN M F+R TI
Sbjct:   40 GNQVKTSKYTVLSFIPKNLFEQLHRFANLYFVGIVILNFIPVVNAFQPGVSMVPVCAILTVTAIKDAWEDFRRYKSDKVINNRESLVYSRKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEHF-HSTIVCEKPNNHLSKFKGYMEHPDQTRT-GFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGTFKEHPPFDVPDADGNFL-SLALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTI 422          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMID----------KIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET-------VLDNIEKF------CRKISKQQLANSDTSKYNNTLY-EYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKR 3753
            YE+ESPDE AL   A      L+ R P  V + +         D L    FDS RKRMSV++  P T  I +Y KGAD+VI+ L+        ID          +  ++++LY+++GLRTL +AK+ + E+ F  W +  R  E +L   E  L+   Q LE  + LLGATGIEDRLQE VP+ +  LR+AGI +WVLTGDK ETA+NIAYS KL ++   ++++   NQET        L++I++F       RK+   ++     S  +  +  E GL+++GKT++ I    +  K FL L  +C+SV+CCRSTP +K+ IV +V+  L V TL+IGDGANDV+MIQ A +GIGI G+EGMQAVM+SDFAI +F +L++LLLVHGH CY +LARM +Y FYK+   V + FW+Q   GFSGS MID    I FNL  T LPP+I G+ DKD  +  L   P++YKSG + + Y    FW ++ D+ +QSL+ F++ YL Y+G+++ +  FG   NT  L     +  +E + W+V H L  +GS L+ +F    + N+ CV    CN+  NPY V+   +  P  YL+  L   +AL PR  + S   T   S++ +A +++  LP  +R + ++ N  S +R
Sbjct:  715 YEAESPDEAALVHAARAYSFTLVSRTPEQVTV-RLPQGICLTFDLLFTLGFDSVRKRMSVVVRHPLTDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKRFHEPQQPARKLCGHRIPPKMPSVNSGAMAPEIGLVIDGKTLNAIFQGKLENK-FLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLM-YFVVSLIYNATCVT---CNSPTNPYWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKA-QKIDKLPIDKR-NLEIQNWRSKQR 1352          

Query:  109 ESRTIYPSVYHDVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATI 1338
            E R +YP+             +   N + TTKY +LTF+P NLFEQF R+AN+YF+ +V LN+ P +  F +E    P+  VL +  VKDG+ED +R+  DR +N     +Y    Q Y +  WQD+  GDFV++  NE +PADIL+  SS+ SG C++ETANLDGE NLKQR+++    + E +  P  F  S I+ E PN  + KF G     D  ++      +L+LRGC +RNT+   GIVIYAG+ETK++LNN+   +KRSK+E++IN D+ +CIG+L ++C+  ++GH +W   F               L +++L GF +F T +IL Q +IP+ LYV+IELVKL Q+F +  DL+LYD++ D   Q RA NITEDLGQIQYIF DKTGTLTEN M F+R TI
Sbjct:   44 EQRVVYPNNSMCHQDWKKVCRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITIFPLATVLLIIMVKDGIEDFKRYCFDREMNSASIQIYERKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEHF-HSTIVCEKPNNHLSKFKGYMEHPDQTRT-GFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGTFKEHPPFDVPDADGNFL-SLALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTI 450          

Query: 1459 LDISIIEEFVLALAVCNTTMVSE-NKNESKIVVE----IPVKSSASFFN----------STHSTKTNTLSNRRTSTGF--NLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQ-KAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLIS------KNTSRQMI--DKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQE-------TVLDNIEKFCRKISKQQLANSDTSKYNNTLYE----YGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCN-TDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDA 3723
            L+   I +F +ALA+CNT +VS  N+   KI +     +P+KS     N          S+ S  +   S+  T   F   +S F   +++PP+      + E   IP+           SN +  +E     ++  +S  +   ++ G  P   ++    YE+ESPDE AL   A      L  R P  V +  D+    +     L + PFDS RKRMSV++  P +  + +Y KGAD+VI+ L+S       N  +QMI  ++   +++ Y+K GLRTL VAK+ +S+ ++ EW     + E ++   E  L+     LE  + LLGATGIEDRLQE VPE +E L +AGI IW+LTGDK ETA+NIAY+ KL   + ++F L   +Q+        +L+ ++K  R     +LA+S  +    +  +     GL++ GKT+   L E +  + FL L + C++V+CCR+TP +K+ +V +V+ +L V TLAIGDGANDV+MIQ A +GIG+ G+EGMQAVMASDFAI++F++L +LLLVHGH CY +L+ M LY FYK+   V + FW+Q   GFSG+ M D    I FNL  T +PP+I G+ +KD  +  L + P++Y+SG   + Y P  FW  ++D+ +QSLV F++ Y  YQG+++ +  FG   NT+ L +   ++++ES+  +  H L  VGS+L ++F       +LCV    CN   NPY ++   M  P  YLV  L T +AL PR + +    +  PS V  A +    LP  +R +A
Sbjct:  631 LETLYIMDFFIALAICNTVVVSAPNQPRQKIGLSSLGGMPIKSLEEIKNIFQKLSVRRSSSPSLASGKDSSSGTPCAFVSRISFFSRPKLSPPMEDESSQMDE---IPQA----------SNSACCTETEAQNRAVGLSVSSAEALS-GPPPSASNLC---YEAESPDEAALVYAARAYRCTLQSRTPEQVMV--DFAALGSLTF*LLHILPFDSVRKRMSVVVRHPLSKQVVVYTKGADSVIMELLSVAASDGTNPEQQMIIRERTQRHLDEYAKRGLRTLCVAKKVMSDTEYAEWLRNHFLAETSIDNREELLVESAMRLENKLTLLGATGIEDRLQEGVPESIEALHQAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSQDACGMLMSAILEELQK--RAQVSPELASSRKNFPQPSDAQGQGRAGLVITGKTLEFALQESL-QRQFLELTAWCQAVICCRATPLQKSEVVKLVRNHLHVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAISQFRHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSVPPIIYGVLEKDVSAETLLQLPELYRSGQRSEEYLPLTFWITLLDAFYQSLVCFFVPYFTYQGSDIDIFTFGNPLNTAALFIILLHLVIESKSLTWIHMLVTVGSIL-SYFFFALAFGALCVT---CNPPSNPYGIMRKHMLDPVFYLVCVLTTFVALLPRFLYRVLQGSVFPSPVLRA-KYFDRLPPEERAEA 1396          

Query:  106 EESRTIYPSVYHDV---------DVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPIS 1404
            + SRT  P+  H V         D    F     +N+++TTKY +L F+P NLFEQF R AN+YF+ +V LN+ P + +F KE   LP++ VL + A+KDG+ED R+++ D+++N++   +Y+   + Y    W+++  GDF+++S NE IPAD+++  S++  G C+IET+ LDGE NLKQRQ++    +++  + P  F+ S I  ESPN ++ +F G ++   N + + L K NL+LRGC +RNT+ V GIV+YAG+ETK++LNN+   +KRSKLE++ N DV+WC+ +LI++C+  ++GH IW+  + N+            +  + L GF +FWT +IL Q +IP+ LYV+IE+VKL Q++ I  D++ Y++K+D   Q RA NITEDLGQIQY+F DKTGTLTEN M F+R ++   D+  +     L S  + +S
Sbjct:   92 KSSRTPRPAGKHRVVIPHLQCFKDEYERFSGTYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDCCWKNVTVGDFIRLSCNEIIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYTEQDSEVDPEKFS-SRIECESPNNDLSRFRG-FLEHANKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGPRYKRSKLERRANTDVLWCVLLLIVMCLTGALGHGIWLSRYENMLFFNIPEPDGRVISPV-LTGFYVFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSTIQCRALNITEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENAKRLESYQEAVS 530          

Query: 1888 FYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQ-EIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLY-------------EYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDF-ESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCY------QGTELS-MAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSI 3666
            +Y+++SPDE AL   A   G     R P  + + +      ++L  L +  F++ RKRMSVI+ +P+ G I LYCKGAD ++L  +   T ++++    +++  Y+ +GLRTL++A + L E+ + EW  R         + E  L ++Y+E+E DM+LLGAT IED+LQ+ VPE +  L  A I IWVLTGDK ETA+NI YS K+  ++  E+F +TG+    V + + K  +K+     A  +   Y   L              EY L++ G +++  L+ D+  + FL  A  CK+V+CCR TP +KA +V +VK   +  TLAIGDGANDV+MI+TAH+G+GI G+EG+QAV+ASD++ ++FK+L+RLLLVHG   Y ++ +   Y FYK+    +V FWF    GFS   + DQ    L+N+  T LP L +G++D+D  E R +E  P++Y+ G     +  R+F+  I   I+ S+++F++ Y  +       GT+L+    F +   TSL+IV    + L++ +W+  +     GSL V +FA +F ++S  +  +  N         +T+ QP  +L + L TA+ + P V  +   L+ +P +
Sbjct:  488 YYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHELGTAITYQL--LAILDFNNIRKRMSVIVRNPE-GKIRLYCKGADTILLDRLHPPT-QELLSSTTDHLNEYAGDGLRTLVLAYKDLDEEYYEEWARRRLQASLAQDSREDRLASIYEEVESDMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFVVTGHTVLEVREELRKARKKMVDSSHAVGNGFTYQGNLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELE-FLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEY-PKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFAEATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAV-YFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIALTTAVCIMPVVAFRFLRLSLKPDL 1095          

Query:   85 CCKESQVEESRTIYPSVYHDVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYR-ITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATI---GFIDFYDDATESA-LTSDSQPISVLAKMLKKCHRNIEIDENLDISI------IEEFVLALAVCNTTMVSENKNESKI 1548
            C K+   EE R    +     D   N   + +SN +KT+KYNI+TF+P+NLFEQF+  AN YF+ ++ L   P+ISS    T  +P++ VL +TAVKD  +D  R +SD +VN+    +  N     E   W ++C GD +K+  N+ + AD+L+  SSE  G CYIETA LDGE N+K RQ I  P   E   ++ ++  +  +I E PN ++ KF+G   +++N     L   N++LRGC+LRNT++  G+VI+AG +TK + N+ +  FKR+ +++ +N  V+W  G L+ + +  +IG+ IW  +    +    +   +E + +    GF+ FW+ +I+  T++P+ LYV++E+++L   + I  D +++  K     + R T + E+LGQ++YIF DKTGTLT+N+M F + +I    + D +D     A L    +P+      L    + +  D +L  ++        EF   L++C+T M SE KNE ++
Sbjct:    4 CAKKRPPEEERRARAN-----DREYNEKFQYASNCIKTSKYNIVTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRHSQVLINGVLQQE--QWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAI--PVTSELGDVSQLARFDGEVICEPPNNKLDKFSGTLYWKEN--KFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIW--EHEVGTRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLAD-KKFLFWDSSLLEAVKMGDPHTHEFFRLLSLCHTVM-SEEKNEGEL 487          

Query:  178 SSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLE--------------------------LYDDK---------VDKRCQVRATNITEDLGQ---IQYIFCD--------KTGTL--------------------------TENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLD---------ISIIEEFVLALAVCNTTMV-SENKNESKIVVEIPVKSSAS--------FFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKF---YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLI---SKNTSRQMIDKIVEN-----MELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET---VLDNIEKFCR-KISKQQLANSDT-----------SKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKS 3639
            + N+LKTTKY +L+F+P NLFEQF R AN+YF+ +  LNF P +++F    A  P+LF+L +TA+KD  ED  R +SD  +NH+ CL+++ + + Y   YW++I  GDFV++  NE IPADIL+  SS+  G C+IETANLDGE NLK+RQ++    +      P++FT S I  E PN ++ +F G ++   N +   L K NL+LRGC +RNT+ V GIVIYAG+ETK+LLNN+   +KRS+LE+Q+N DV+WC+ +L+ + +  ++GH +W++ +     +     S+ +  + +      F+T +I+ Q +IP+ LYV+IE+VK+ Q++ I +D+E                          ++ DK         V +RC V     + D       +Y   D        K GT+                          T +  E KRA++        A  S +  D  P   L + + +C R + I  + +         +S + +F +AL +CNT +V S ++   K+ V   +KS           F  S  ++  +++ N  TS   + S          LP        + +    L  LE     +  S+ S G   Q     S  +    +Q KCP +     +    YE+ESPDE AL   A      L+ R    V + +  H      + L    FDS RKRMSV++  P T  I +Y KGAD+V++ L+   S + +R    K + +     + LY+  GLRTL +AKR LS++++  W       E ++ + E  L      LE ++ LLGATGIEDRLQE VPE +  LR+AG+ IWVLTGDK ETAINIAY+ KL +  +E+ TL  ++QE    +LD    + + +  +  L NS++           S   +      L+++G++++  L++ +  K FL LA  C+SV+CCRSTP +K+ +V +V+  L+  TLAIGDGANDV+MIQ A VG+GI G+EGMQAVMASDFA+ +F+YL RLL+VHGH CY +LA M LY FYK+++ V + FWFQ   GFS S MIDQ   I FNL  + LP L+ G+ DKD  + +L R PQ+YKSG +++ YRPR FW N+VD+ +QSLV F++ YL Y  +++ +  +G       L     ++ +E++ W+  +WL+C  S  + +F+   + N+ C         NPY  +   +  P  YL   +    AL PR+  K+
Sbjct:   64 ADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSREEKKYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFT-SVIECEKPNNDLSRFRG-YIMHSNGEKAGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLARYQEADSEEEEVVSKVGTISHRGSTGSHQSIWMTHKTQSIKSHRRTGSRAEAKRASM---LSKHTAFSSPMEKDITPDPKLLEKVSECDRFLAIARHQEHPLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRQKVRVRFELKSPVKTIEDFLRRFTPSRLASGCSSIGNLSTSKSSHKSGSAF------LP--------SLSQDSMLLGLEEKLGQTAPSIASNGYASQAGQEESWASECTTDQ-KCPGEQREQQEGELRYEAESPDEAALVYAARAYNCALVDRLHDQVSV-ELPHLGRLTFELLHTLGFDSIRKRMSVVIRHPLTDEINVYTKGADSVVMDLLLPCSSDDARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAEASVESREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSQEACAALLDQCLSYVQSRNPRSTLQNSESNLSVGFSFNPVSTSTDASPSPSLVIDGRSLAYALEKSLEDK-FLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVDVFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFL-FFSVALIYNTSCATCYP--PSNPYWTMQTLLGDPLFYLTCLIAPIAALLPRLFFKA 1308          

Query:  178 SSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLF----------------------HITRDLE----LYDDK---------VDKRCQVRATNITED-----LGQIQYIFCDKTGTLTENLMEFKRATIGF-----IDFYDDATESALTSDSQPISVLAKMLKK------------------------CHRNIEI---DENL------DISIIEEFVLALAVCNTTMV-SENKNESKIVVEI----PVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS--------RQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET---VLDNI-------------EKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKS 3639
            + N+LKTTKY +L+F+P NLFEQF R AN+YF+ +  LNF P +++F    A  P+LF+L +TA +D  ED  R +SD ++NH+ CL+++ + + Y   +W++I  GDFV++  NE  PADIL+  SS+  G C+IETANLDGE NLK+RQ++    +      P++FT S I  E PN ++ +F G  +  DN K   L K NL+LRGC LRNT  V GIVIYAG+ETK+LLNN+   +KRSKLE+Q+N DV+WC+ +L+ + +  ++GH +W+  +    ++ +   S+ +  +        F T +I+ Q +IP+ LYV+IE+VK  Q++                      +IT DL     ++ DK         V +RC V     + D     L + Q    ++   +       +R +IG      +     +T+S   + S+  +  A ML K                        C +++ +    E+L      ++S + +F +AL +CNT +V S ++  +K+ V      PVK+   F      +   +  +   S   N S   +    P  P S             L  LE        ++ S G   Q  +  S+L +   ++ +           YE+ESPDE AL   A      L++R    V + +  H      + L    FDS RKRMSV++  P T  I +Y KGAD+V++ L+   +S        +++  K    + +Y+  GLRTL +AKR LS++++  W       E +L  SE  L      LE ++ LLGATGIEDRLQ+ VPE +  LR+AG+ IWVLTGDK ETA+NIAY+ KL + ++E+ TL   +QE    +LD               EK   K+S +  +    S    +     L+++G++++  L++++  K FL LA  C+SV+CCRSTP +K+ +V +V+  L+  TLAIGDGANDV+MIQ A VG+GI G+EGMQAVMASDFA+ KF+YL RLL++HGH CY +LA M LY FYK+++ V + FWFQ   GFS S MIDQ   I FNL  + LPPL+ G+ D+D  + VL  NPQ+YKSG +++ YRPR FW N+ D+ +QSLV F + YL Y  + + +  +G    T  L+    ++ +E++ W+  +W++C  S+L+ +F    + N+ C         NPY  +   +  P  YL   +    AL PR+  +S
Sbjct:   60 ADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFT-SVIECEKPNNDLSRFRG-CIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPRGGSVSQRGSIGSHQSVRVVHRTQSTKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTKVRVRFELKSPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSSHKLGSSFPSTPSSD----------GMLLRLEERLGQPTSAIASNGYSSQADNWASELAQEQESEREL---------RYEAESPDEAALVYAARAYNCVLVERLHDQVSV-ELPHLGRLTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDK-FLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLL-FFTVALIYNASCATCYP--PSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRS 1294          

Query:  166 ILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXX--XXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELD--ALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQEL-ERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDT--SKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDF---WRNIV----DSIWQSLVIFWLTY-------LCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCV---GSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMK-QPKTYLVVTLVTAIALFP 3621
            +L+ +SN + TT+YN++TF+P  L+EQF R AN YF+    L+ FP +S F K +   P++FV+ L+  K+ +ED RR+  D +VN     ++  D  ++    W+ +  GD VK+  ++  PAD+L+  SS   G CY+ET NLDGE NLK ++ +      E   T  SF+ + I  E PN  +Y F G    E + +   L  S ++LR   LRNT +V G+V++ G++TK + N+ +   KRS++E++++  +     +L+++    S+G  +  K                  N +N      +   T ++L+  +IP+ LYV+IELVK+ Q   I +DL++YD +     Q R +N+ E+LGQ+  I  DKTGTLT N M+F + +I    +   A+E  L +        AK +      I++DE       EE          T +   +       ++P K+S+     T  T T+   ++  STG     F  Q +   +  + +    + +I   L++L    +      I E                + + GKC Y         E+ESPDE A    A + G +  +R    V I + +  +  E +   L V  F S RKRMSVI+ D + G I L CKGAD++I   +SKN  +  ++   +++  Y + GLRTL ++ R+L E ++  WN+ F   + ++ A   E+L    ++ E+++IL+GAT +ED+LQ+ VP+C++ L +AG+ IWVLTGDKMETAINI Y+  L  +  +   +   N+E    + E   R+    Q+ N+        +    + LI++GKT++  L++DI  + FL LA  C SV+CCR +P +KA +  + K      TLAIGDGANDV MIQ A +G+GI G EGMQAVMASDF+I +F++L RLL+VHGH CY ++A+M  Y FYK+    L  F+F+   GFSG  + +    +LFN+ +T LP + LG++++D  S V  + P +Y+ G       P++    W  I+    + ++ S+VIF L          C  G    M   G    T ++      + L     S F W+  V   GS +V W+  + L   L   +    + N + +++ T+   P  +L   LV A    P
Sbjct:   55 VLRYTSNYVSTTRYNLITFLPKCLYEQFHRVANFYFLVAAILSVFP-LSPFNKWSMIAPLIFVVGLSMGKEALEDWRRFMQDVKVNSRKATVHRGDG-DFGRRKWKKLRVGDVVKVEKDQFFPADLLLLSSSYEDGICYVETMNLDGETNLKVKRCLDVTLPLERDDTFQSFSGT-IKCEDPNPNLYTFVGN--LEYDGQVYPLDPSQILLRDSKLRNTSYVYGVVVFTGHDTKVMQNSTKSPSKRSRIEKRMDYIIYTLFALLVLVSFISSLGFAVMTKMHMGDWWYLRPDKPERLTNPRNPFHAWVVHLITAVLLYGYLIPISLYVSIELVKVLQATFINQDLQMYDSESGTPAQARTSNLNEELGQVDTILSDKTGTLTCNQMDFLKCSIAGTSYGVRASEVELAA--------AKQMA-----IDLDEEQG----EE---------VTHLPRTRGRMHGYAKMPSKTSSDIELETVITATDE-GDQTQSTGIKGFSFEDQRL---MGGNWLNEPNSDDILMFLRILAVCHT-----AIPE---------------VDEDTGKCTY---------EAESPDEVAFLVAAGEFGFEFTKRTQSSVFISERHSGQPVEREYKVLNVLDFTSKRKRMSVIVRD-EKGQILLLCKGADSIIFERLSKN-GKNYLEATSKHLNGYGEAGLRTLALSYRKLDETEYSIWNSEFHKAKTSVGADRDEMLEKVSDMMEKELILVGATAVEDKLQKGVPQCIDKLAQAGLKIWVLTGDKMETAINIGYACSLLRQGMKQIYIALRNEEGSSQDPEAAARENILMQIINASQMIKLEKDPHAAFALIIDGKTLTYALEDDIKYQ-FLALAVDCASVICCRVSPKQKALVTRLAKEGTGKTTLAIGDGANDVGMIQEADIGVGISGVEGMQAVMASDFSIAQFRFLERLLVVHGHWCYKRIAQMICYFFYKNITFGLTLFYFEAFTGFSGQAIYNDSYLLLFNVILTSLPVIALGVFEQDVSSEVCLQFPALYQQG-------PKNLFFDWYRIIGWMANGVYASVVIFSLNIGIFHVQSFCSGGQTADMDAMGTAMFTCIIWAVNVQIALT---MSHFTWIQHVLIWGS-IVTWYIFLALFGMLPPKV----SGNIFHMLSETLAPAPIFWLTSLLVIAATTLP 1149          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS----------RQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET-------VLDNIEKFC------RKISKQQLANSDTSKYNNTLY-EYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTD-NPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLP----------WRQRK 3717
            YE+ESPDE AL   A      L+ R P  V + +           LC   FDS RKRMSV++  P TG I +Y KGAD+VI+ L+               R++  +  ++++LY+++GLRTL +AK+ +SE+ F  W +  R  E +L   +  L+   Q LE  + LLGATGIEDRLQE VP+ + TLR+AGI +WVLTGDK ETA+NIA+S +L N+   ++T+   NQET        L+ +++F       RK+   +L +   S  +  +  E GL+++GKT++ I  +  + K FL L  +C+SV+CCRSTP +K+ IV +V+  L+V TL+IGDGANDV+MIQ A +GIGI G+EGMQAVM+SDFAIT+FK+L++LLLVHGH CY +LARM +Y  YK+   V + FW+Q   GFS S MID    I FNL  T LPPL+ G+ DKD  +  L   P++YKSG + + Y    FW ++VD+ +QSL+ F++ YL Y+G+++ +  FG   NT  L     +  +E + W++FH +  +GS L+ +F    L N+ CV+   CN+  NPY V+   +  P  YLV  L   +AL PR    S   T   S++ +A +++  LP          WR R+
Sbjct:  717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTV-RLPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIF-QGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLM-YFLVSLLYNATCVI---CNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKA-QKIDKLPPDKRNLEIQSWRSRQ 1353          

Query:  109 ESRTIYP--SVYH-DVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATI 1338
            + R ++P  S++H D + +S    +   N+  TTKY + TF+P NLFEQF R+AN+YF+ +V LN+ P +  F +E   LP+  VLF+  +KDG+ED +R + D+ +N     +Y    Q Y    W+D+  GDF+++  NE +PADIL+  SS+ +G C++ETA+LDGE NLKQR ++    ++E +  P  F  + I+ E PN  + KF G     D  ++      +L+LRGC +RNT+   GIVIYAG+ETK++LNN+   +KRSK+E+++N D+ +CIGILI++C+  ++GH IW   F           +   L + +L GF +F T +IL Q +IP+ LYV+IELVKL Q+F ++ DL+LYD++ D   Q RA NI EDLGQIQYIF DKTGTLTEN M F+R TI
Sbjct:   44 QQRVVFPNNSIFHQDWEEVSR---RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNT-IVCEKPNNHLNKFKGYMEHPDQTRT-GFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPS-ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTI 450          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKA-FELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS-------RQMI--DKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKY---NNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCN-TDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKS 3639
            YE+ESPDE AL   A      L  R P  V +  D+          L + PFDS RKRMSV++  P +  + +Y KGAD+VI+ L+S  +        +QMI  +K   +++ Y+K GLRTL +AK+ +S+ ++ EW     + E ++   E  LL     LE  + LLGATGIEDRLQE VPE +E L KAGI IW+LTGDK ETA+NIAY+  L +              T+L  ++K  + + +Q   + D  +     ++    GLI+ GKT+   L E +  K FL L S C++VVCCR+TP +K+ +V +V+ +LQV TLAIGDGANDV+MIQ A +GIG+ G+EGMQAVMASDFA+++FK+L +LLLVHGH CY +L+ M LY FYK+   V + FW+Q   GFSG+ M D    I FNL  T  PP+I G+ +KD  +  L + P++YKSG   ++Y P  FW  ++D+ +QSLV F++ Y  YQG+++ +  FG   NT+ L +   ++++ES+  +  H L   GS+L ++F    +  ++CV    CN   NPY ++   +  P  YLV  L T IAL PR + + 
Sbjct:    7 YEAESPDEAALVYAARAYQCTLQSRTPEQVMV--DFAASGPLTFQLLHILPFDSVRKRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGAGPEKQQMIIREKTQRHLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACMLMS--------------TILKELQKKTQALPEQVSLSVDLHQPPVPQDSGLRAGLIITGKTLEFALQESL-QKQFLELTSWCQTVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYKSGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQGSDIDIFAFGNPLNTAALFIILLHLIIESKSLTWIHMLVITGSIL-SYFLFAIVFGAMCVT---CNPPSNPYWIMQEHVLDPVFYLVCILTTCIALLPRFVYRG 582          

Query:  178 SSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF-----------YDDATESALTSDSQP-----ISVLAKMLKKCHRNIEIDENLD-----------ISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIP-KNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS---RQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISK--------------------------------------QQLANSDTSKYNNTLY---EYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKS 3639
            + N ++TTKY +L+F+P NLFEQF RFAN+YF+ +V LN+ P+I++FGKE A +P+LFVL +TA+KD  ED RR+ SD+RVN+  C +YN  S  Y  + W+ +  GD V +S NE IPADIL+ RSS+  G CYIETANLDGE NLKQRQ++    +      P+SFT S +  + PN +IY+F+G ++   N + + +   NL+LR C+L+N  FVEGIV+YAG ETK++LNNN   +KRSKLE+ +NRD++WCI IL++LC   +IG  +W++ + N   ++F  +  EN    +++GFI FWT +I+ Q +IPL LYV+IE++KL Q+FHI  D+EL+D++ ++R + RA NI E+LGQ+QYIF DKTGTLTEN M F+R TIG  D+            +D    + +  ++P     +  L   L++   N+E    +D              ++EF L +A CNT +VS+  ++  +       SS  + N+  +  T+    R                +PP+ P    +  +   P      + +  S+S  S  +    +         +         P     L   YE+ESPDE AL   A + G +LL+R P  V +     +   E   L + PFDS RKRMS+I+  P T    LYCKGAD+ ILPL++       RQ+I +  +++  YSK GLR L +AK+ L ++++ EW  + +  E ++  +E  L++  + +E ++ LLGATGIEDRLQE VPE +  LR AGI IWVLTGDK ETA+NIAYS +LF+ + E+ TL   +QE   + I  +  ++ +                                       ++ N    ++  +L    +  L+++G+T+S IL+     + FL LA  C  V+CCR+TP +KA +V+++K  L V TLAIGDGANDV+MIQ A +G+GI G+EGMQAVMASDFA+ +F+YL RLLLVHGH CYD+LAR  +Y FYK++  + + FW+Q+  GF+GSVMIDQ+  +L+N+  T LPPLILGI+D+D  + +L + P +Y  G   K+Y    FW N++D+++QS+++F++ +  Y  +++ + EFG    TS   V   ++ +E + W++ H +S V S  V +F    L NS+C      +  NPY V+ H M   + +  + L+  I+  PR ++++
Sbjct:   29 ADNAVRTTKYTLLSFVPRNLFEQFHRFANLYFLGIVLLNWVPQINAFGKEVAMIPVLFVLGVTAIKDAFEDHRRYVSDKRVNNSTCRVYNKQSGRYVKTLWKHVRVGDIVHLSCNEVIPADILLLRSSDEQGLCYIETANLDGETNLKQRQVVRGYAQHSDTFHPLSFT-STVECDPPNCKIYRFHG-FICHPNGEKVPITSDNLLLRDCVLKNADFVEGIVVYAGFETKAMLNNNGPRYKRSKLERFMNRDIVWCIVILLVLCSVGAIGCAMWLRSYENRREIIFIPYEQENRYIPAVEGFIAFWTYIIILQVMIPLSLYVSIEIIKLGQVFHIHEDIELFDERSNRRLECRALNIPEELGQVQYIFSDKTGTLTENHMVFRRCTIGGRDYNHHHPSVSEAEENDIKIRSYSCGTKPSKDDTVFTLNPQLQRELSNMEYQLRMDGGGQQLFLSPESQRVQEFFLLMATCNTVIVSKYPHKDLM------NSSGLYLNNGGAHPTSPDGYR----------------SPPIRPPASAVPSSLPSPVARSPAVASTPSESRASTPTRPHKLALPFLNFVSSPSRRTLTPSPTPSPQLQPIYEAESPDEIALVDAASRYGCRLLRRTPDSVTLMLP-GEGLIEYRVLHLLPFDSFRKRMSIILQHPITKAKVLYCKGADSAILPLLAPTKDQAMRQVIVRTQQHLNQYSKKGLRVLCMAKKVLEDEEYEEWLEQHKASELSVGDAEERLVSSARLMETNLELLGATGIEDRLQEGVPETIAALRAAGIVIWVLTGDKQETAVNIAYSCRLFSADMEVITLNARSQEATEETIRFYLEQVERCLTCFSADIDETQRRRSFSTLLSRLGNFLFGRRGPARNDEVGNDAQPRFGASLRHRKKRALVIDGRTLSYILERS-ADQLFLRLAQQCSVVLCCRATPLQKACVVNLIKDRLNVLTLAIGDGANDVSMIQAADIGVGISGQEGMQAVMASDFALARFRYLERLLLVHGHWCYDRLARAVVYFFYKNAAFIFILFWYQLYCGFTGSVMIDQLYLMLYNVLFTSLPPLILGIYDQDCPAHLLLKRPALYTPGRKSKTYTKYSFWVNMLDALYQSIIMFFVPFFVYYDSDVDIWEFGTTICTSCFCVQMLHVAIECKSWTLMHGMSIVASFFV-YFGFALLYNSVCY--DSPSLQNPYWVMQHAMASAQFWFCLLLIPVISCLPRFVVRA 1225          

Query:   91 KESQVEESRTIYPSVYHDVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIH--DPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF------YDDATES----ALTSDSQPI--------SVLAKMLKKCHRNI-EIDENL----------DISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNR---RTSTGFNLSVFGIQEINP---PLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTS-----RQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKY-NNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPS-IVYEALRRLQNLPWRQRKDADLGNLESNKRVDEESSNTIFDYLKFNANKSKEECQESTYFSFLKGNKILPSNVQDTNNS 3900
            K   V  + T+ PS+ H      N   +   N++KTTKY +LTF P N+FEQF RFAN+YFI VV LN+ P+I +FGKE A +P++FVL +T +KD  ED RR++SD+++NH  C LY +D + Y    W DI  GDFV +S NE IPADI++ +SS+  G C+IET NLDGE NLKQRQ ++  D  K  ++     FT   +  + PN EIYKF G  +  +    I+L K NL+LRGC +RNT +VEGIV+YAG++TK++LNN    +KRSKLE+ INRDV+WC+ +L+ LC  C+I   IW+  + +   V F  + ++   N   Q F++F+T +I++QT+IPL LYV++ELVKL Q++ IT D+ +Y + +DKR + RA NITEDLGQ++YIF DKTGTLTEN MEFK  TI   D+       DD +E+    +L S S  +         +  ++ K C R++  +D  L          +  II+EF L +A+CNT +VS + +E  +     V       +     K N    +     +    L+  G +   P    LPP    I  T +  +N ++     S S     SEGS+   S       R                  YE+ESPDE AL K +C  G  LL+R P  V +W     +  E + L V  FDS RKRMSVI+ +P +  I LY KGAD+ +L ++ K        + M+ +  +++  Y+  GLRTL +AK+ L    +  W  RF+  + +L   E +L+ +  E+E+D+ LLGATGIED+LQ++VP  +  LR+AGI +WVLTGDK ETAI IAY+ +LF+ N  I  L   ++ T  D +E+   +I++    N ++S+  N    EY L+++G T++  LD+++    FL L   CKSVVCCRSTP +K  +V +V+ +LQ  TLAIGDGANDV+MI  A +G+G+ G+EGMQAVMASDFAI +F +L+ LLLVHGH CY +LAR S  MFYK  I++ V +W+Q  + FSGS+  D +  +L ++  T LPP++  + DKD  +  L   P++YK G   K Y    F+  ++DS++QS+++++++YL Y    + + EFG    T+L++     + +++  W    WL+ + S LV WF   F + S  V     +  NPY V+ HTM +P   +VV L T +AL PR +++    T RP  IV   L         + K++D+   E++   +     T+ D L+ + + S+    + T   F  G    P +   TN+S
Sbjct:   14 KTRTVVPNHTLDPSIQHRAKNHPNKDFR--GNRIKTTKYTLLTFFPKNIFEQFHRFANLYFILVVALNWVPQIQAFGKEIAMVPVIFVLAVTCIKDAFEDFRRYKSDQKINHTQCRLYKSDEERYVKGEWHDIHVGDFVHLSCNEIIPADIVLVKSSDHQGICHIETCNLDGETNLKQRQAVYGIDYGKDGFKAKMFDFT---LECDLPNSEIYKFKGYII--NQGDKISLNKDNLLLRGCTVRNTDYVEGIVVYAGHDTKAMLNNRNPRYKRSKLERHINRDVVWCVILLLFLCFFCAIASGIWLGGYKDRHLVPFIPYESDEWYNPYFQAFVVFFTYIIIYQTVIPLALYVSVELVKLGQVYFITNDIRMYYEPMDKRVECRALNITEDLGQVEYIFSDKTGTLTENQMEFKSCTINGKDYPHAPESEDDMSETGSRFSLASRSSTVLENLNLEPDLQRELSKMCMRSLNSVDLTLPDPPPLTKSENTKIIQEFFLLMAICNTVVVSTHAHEDLMDESGIVHDPHQQKHDKEKQKLNDFYRKLPEPAAKKSQLAPLGQENSTPKSLALPP----ISGTADF-QNRELYNRFDSSSPALTPSEGSIAGSSFMSDMSQRTQ----------------YEAESPDELALVKASCTYGCCLLKRSPDKVTVWLPADGEV-EFETLDVLTFDSTRKRMSVIVRNPVSEEIILYTKGADSQVLSVLHKKYKQDPVLKDMVRRTEDHILDYAVRGLRTLCMAKKVLDLDYYKNWRVRFKEADASLENREEQLIDVACEIEQDLELLGATGIEDKLQDDVPATISKLRRAGIKVWVLTGDKQETAIQIAYASQLFDTNMHIMVLNATDKNTTRDLLEEHITQINR----NKESSQVENKPKKEYALVIDGHTLAYALDKEL-EATFLKLTVRCKSVVCCRSTPIQKGMVVKLVRDHLQKLTLAIGDGANDVSMIHVADIGVGVSGQEGMQAVMASDFAICRFHHLQDLLLVHGHWCYSRLARFSSIMFYKSLILIFVLYWYQFDSAFSGSLQFDSLFTMLKHVLFTALPPIVNAVMDKDVSAETLLSKPELYKVGPQDKLYTRMSFFMALLDSLYQSVILYYVSYLAYLYEPVGVWEFGTTSFTALILTCLLTIAIDTESWVWPQWLTTIFSFLVFWF---FAILSNAVWFTFDHPANPYWVMIHTMTKPIHTVVVLLSTVLALLPRFVIRILQRTIRPDEIVISQLEE----KLLEYKESDMEMQENDNMTNTTEITTVDDSLQGSTSTSR---NQDTGIKFRNGRLSKPRHSIPTNDS 1283          

Query:  172 KQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF-----YDDATESALTSDSQPISVLA--KMLKKCHRNIEIDENL------DISIIEEFVLALAVCNTTMVSENK-----NESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVN-------QGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCI-WKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLIS--KNTSRQ--MIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETV-------LDNIEKFCRKISK--QQLANSDTSKYNNTLYEYGLILEGKTISVILDEDI-VTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLV---AWFAEIFLLNSLCVVIVDC-NTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMK 3636
            K+ +NK++TTKY +L+F+P NL EQF R AN+YFI +V LN+FP I++FGKE A +P++FVL +TAVKD  ED RR  SD+R+N+  C +Y +++  Y+   W+++  GD + +S NE +PADIL+ RSS+ SG CYI+T +LDGE NLKQRQ+      ++    P  F  S + VE+P  +IY+F+G  +   + + + +   N++LR C+L+NT FVEGIV+YAG+ETK++LNN    +KRS LE+Q+N+DV+WC+ ILI+LC+  +IG  +W+  F+ + +      S         + F+ FWT +I+ Q +IPL LYVT+E+ K+ Q++HI  +++LYD  +DKR + RA NITE+LGQIQYIF DKTGTLTEN M F+R  I  +D+      D+     LTS    +SV+A  ++L   ++   + E +        + I+EF+L LAVCNT + S +      N S ++  +P    +SF   + S K   L   R+ T              P PP       T          E + S S+  V     L        + +  N+        +   P   D L   +E+ESPDE AL   A     KLL+R P  VC+ + D  +  +E+  L V PFDS RKRMSVI+  P +G I L+CKGAD+ I P ++  ++ S Q  +I+K   ++  YSK+GLR LL+AKR LS +++ EW+ + R +  +L   E ++   Y  +E ++ LLGATGIEDRLQE VPE L  L  AGI +WVLTGDK ETAINIAYS KLF+   E+  L   ++ET        L  IE     I       +  D ++         L+++GKT++ ILD    +TK FL L +HC SV+CCR+TP +KA IV +VK  L++RTLAIGDGANDV+MIQTA VGIGI G+EGMQAVMA+DFA+++FK+L RLLLVHGH  YD+L+RM LY FYK++  V + FW+Q+  GFSGSVMIDQ+  +L+NL  T LPPL +G++D+D    +L   P +Y+ G   K Y+   FW  + D+I+QSL IF++    Y  +++ M EFG    T+ + V   ++ +E R W++ H    VGS+++   A++   FL NSLC   V+C    + Y ++     +P  +LV  L   +AL PR + +
Sbjct:  194 KRPNNKIRTTKYTLLSFLPRNLLEQFHRVANLYFIFIVLLNWFPAINAFGKEIAMIPVMFVLGVTAVKDLFEDRRRHASDKRINNSTCRIYQSEAARYKKVLWKEVRVGDLIHLSNNEVVPADILLLRSSDPSGLCYIDTGHLDGETNLKQRQVARGFVSKQDVFEPSKF-RSKVEVEAPTTKIYRFHGA-IVHPSGERVPVGTDNILLRECLLKNTDFVEGIVVYAGHETKAMLNNGGPRYKRSSLERQMNQDVLWCVLILIVLCLIGAIGCKLWLNIFNRLESPFKAEHSE------GTEAFLAFWTYIIILQIMIPLSLYVTLEMCKIIQVYHIHHNVDLYDSIMDKRTECRALNITEELGQIQYIFSDKTGTLTENRMIFRRCAIAGVDYNHPKMEDEGKNGKLTS----LSVVANPRLLSDLNQVGAVTEQIYTTRQTHAAKIQEFLLLLAVCNTVVCSRHPHYDMMNASGLIEAVP----SSF---SQSDKYTRLEESRSVT--------------PSPPLNYLEGRT---------TELSCSSSDVEVKKPKLLSLPLLGRKQGSNTNLTDEQKAKLRSSTPSPHD-LKPIFEAESPDELALVDAAFNYNCKLLKRTPTSVCVEFFDEGRVTYEI--LDVLPFDSIRKRMSVIVKHPVSGEIILFCKGADSSIFPYLAPVEDDSEQKILINKTQNHVNNYSKDGLRILLMAKRVLSLQEYTEWSKKQRELNMSLDNFERKVQESYSRIECNLTLLGATGIEDRLQEGVPETLSALMSAGIVVWVLTGDKPETAINIAYSSKLFSPQMELLKLMTRSKETAESTIMFYLSEIENAASSIQTVLPTTSRRDLNRSGPKNRSKALVIDGKTLTFILDRRSNLTKPFLKLTAHCSSVLCCRATPLQKAYIVKVVKEELKMRTLAIGDGANDVSMIQTADVGIGISGQEGMQAVMAADFALSRFKFLERLLLVHGHWSYDRLSRMVLYFFYKNAAFVFLCFWYQLFCGFSGSVMIDQMYLMLYNLLFTSLPPLAIGVYDQDAPEELLRDRPYLYRQGRLGKVYKSYSFWLTMADAIYQSLCIFFICQGAYADSDIDMFEFGTTATTACMFVMLLHVSIEIRSWTIIH----VGSIVISIGAFYVYSFLYNSLC---VNCFGLPSTYWIIQKATSRPTYWLVTLLSCVVALLPRYVFR 1340          

Query:  175 QSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF--YDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISI------IEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLS-----NRRTSTGFNLSVFGIQEINPPLPPSQITIQ----ETFNIPKNLKMLETNKSDSNKSVISEGXXXXXX--------XXXXXXNRYNVNQGKCPYKDDVLFKF------------YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISK----NTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEW---NNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKIS---------KQQLANSDTS------KYNNTLYEYGLILEGKTISVILDEDI-VTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDC-NTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEAL 3681
            + +NK++TTKY +L+F+P NL EQF R AN+YFI +V LN+FP I++FGKE A +P+LFVL +TAVKD  ED RR  SD+RVN+  C +Y +++  Y+   W+++  GD + +S NE +PADIL+ R+S  +G CYI+T +LDGE NLKQR++     K++    P  F  SHI V++P  +IY+F+G  +    A+ + +   NL+LR C+L+NT +VEGIV+YAG+ETK++LNN    +KRS LE+Q+N+DV WC+ +L+ILC+  ++G  +W++ ++ +        S+E     S + F+ FWT +I+ Q +IPL LYVT+E+ K+ Q++HI  +++LYD + DKR + RA NITE+LGQ+QYIF DKTGTLTEN M F+R TI  +D+  ++   E      S  +SV+     K   + ++ E   I+       I+EF+L LAVCNT + S + +   +     +++ ++ F ++ S + N++       +  ST              P PP             ++P +L  + + +S  N   I++   I+ S        S     N+ N N   C   D+   K             +E+ESPDE AL   A     +LL+R PG V I     +   E + L V PFDS RKRMS+I+  P T  IT+YCKGAD+ ILP ++     +  +Q+I++  + +  Y+  GLR LL+AKR LS  ++ +W   +  ++++ +N    +++L   Y  LER + LLGATGIEDRLQE VPE L +L  +GI +WVLTGDK ETAINIA+S KLFN + EI  +   +++   D I+ +  +I          ++   +S TS      + N   Y   L+++GK+++ ILD+   +TK FL L + C SV+CCR+TP +KA IV +VK  L++RTLAIGDGANDV+MIQTA VGIGI G+EGMQAVMA+DFA++KFKYL R LLVHGH  YD+LARM LY FYK++  V + FW+Q+  GFSG+VMIDQ+  +L+NL  T LPPL +G++D+D    +L + P +Y+ G   K YR   FW  + D+++QSL IF++    Y  T + + EFG    T  + V   ++ +E + W++ H  S V S + A++    L NSLC   V+C    + Y V+ H +  P  +L   L   IAL PR++      T  P  V  AL
Sbjct:  195 RPNNKVRTTKYTLLSFLPRNLLEQFHRVANLYFIFIVLLNWFPAINAFGKEIAMIPVLFVLGVTAVKDLFEDRRRHASDKRVNNSTCRIYQSEAARYKKVLWKELRVGDLIHLSNNEVVPADILLLRTSAPNGVCYIDTGHLDGETNLKQREVPRTFLKKQEIFEPSKF-RSHIEVDAPTTKIYRFHGAMLHPSGAREV-VGTENLLLRECLLKNTDYVEGIVVYAGHETKAMLNNGGPRYKRSALERQMNQDVFWCVLVLVILCVIGAVGCKLWLQAYNQIKEPFKLEASSE-----STEAFLAFWTYIIILQIMIPLSLYVTLEMCKIIQVYHIHHNVDLYDTETDKRVECRALNITEELGQVQYIFSDKTGTLTENRMIFRRCTIAGVDYNHHNLENEGRGAKASAALSVIINPKLKEDLDSQLSEQSTIAQQRHAARIQEFLLLLAVCNTVVCSHHPHCDLMNASGVIEAVSNVFATSGSARLNSIDCTDRDGQMHSTNDKYERLKESRSVTPSPPLNSHTHNDSLRATHVP-SLTPINSVESSPNAEEIAQSCAIKSSFRPKLNISSLPFLGNKRNGNS--CNLTDEQKAKLNCSTTLFDSKPIFEAESPDELALVDAAYSYNCRLLKRNPGSV-IVDVPGEGILEYEILQVLPFDSYRKRMSIILRHPHTNEITVYCKGADSSILPNLAPIEDDSEQKQIINRTQQQLHTYASKGLRVLLMAKRILSFSEYTDWLAMHQEYQLLHEN---RDSKLRESYSMLERKLSLLGATGIEDRLQEGVPETLVSLVASGIVVWVLTGDKQETAINIAFSAKLFNSDMEILKIMARSKKAAEDTIKCYLTEIEECSESNGSDRRSQPSSSTSELLRRTRVNRKKYSRALVVDGKSLTYILDKRSNLTKHFLKLTTFCNSVLCCRATPLQKAYIVKVVKEELKMRTLAIGDGANDVSMIQTADVGIGISGQEGMQAVMAADFALSKFKYLERFLLVHGHWSYDRLARMVLYFFYKNAAFVFLIFWYQLYCGFSGAVMIDQMYLMLYNLLFTSLPPLAIGVYDQDSPEDLLRQKPYLYRKGRLGKVYRSFSFWLTLADALYQSLAIFFICVAVYMDTAIDIWEFGTTVTTICMFVMSCHVAIEIKSWTIIHVASIVIS-IGAFYVYSILYNSLC---VNCFGLPSTYWVIQHAIISPTYWLSTLLSIVIALLPRLVFLVIKNTISPDDVTRAL 1406          

Query:  175 QSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF--YDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISI------IEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLS-----NRRTSTGFNLSVFGIQEINPPLPPSQITIQ----ETFNIPKNLKMLETNKSDSNKSVISEGXXXXXX--------XXXXXXNRYNVNQGKCPYKDDVLFKF------------YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISK----NTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEW---NNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKIS---------KQQLANSDTS------KYNNTLYEYGLILEGKTISVILDE-DIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDC-NTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEAL 3681
            + +NK++TTKY +L+F+P NL EQF R AN+YFI +V LN+FP I++FGKE A +P+LFVL +TAVKD  ED RR  SD+RVN+  C +Y +++  Y+   W+++  GD + +S NE +PADIL+ R+S  +G CYI+T +LDGE NLKQR++     K++    P  F  SHI V++P  +IY+F+G  +    A+ + +   NL+LR C+L+NT +VEGIV+YAG+ETK++LNN    +KRS LE+Q+N+DV WC+ +L+ILC+  ++G  +W++ ++ +        S+E     S + F+ FWT +I+ Q +IPL LYVT+E+ K+ Q++HI  +++LYD + DKR + RA NITE+LGQ+QYIF DKTGTLTEN M F+R TI  +D+  ++   E      S  +SV+     K   + ++ E   I+       I+EF+L LAVCNT + S + +   +     +++ ++ F ++ S + N++       +  ST              P PP             ++P +L  + + +S  N   I++   I+ S        S     N+ N N   C   D+   K             +E+ESPDE AL   A     +LL+R PG V I     +   E + L V PFDS RKRMS+I+  P T  IT+YCKGAD+ ILP ++     +  +Q+I++  + +  Y+  GLR LL+AKR LS  ++ +W   +  ++++ +N    +++L   Y  LER + LLGATGIEDRLQE VPE L +L  +GI +WVLTGDK ETAINIA+S KLFN + EI  +   +++   D I+ +  +I          ++   +S TS      + N   Y   L+++GK+++ ILD+   +TK FL L + C SV+CCR+TP +KA IV +VK  L++RTLAIGDGANDV+MIQTA VGIGI G+EGMQAVMA+DFA++KFKYL R LLVHGH  YD+LARM LY FYK++  V + FW+Q+  GFSG+VMIDQ+  +L+NL  T LPPL +G++D+D    +L + P +Y+ G   K YR   FW  + D+++QSL IF++    Y  T + + EFG    T  + V   ++ +E + W++ H  S V S + A++    L NSLC   V+C    + Y V+ H +  P  +L   L   IAL PR++      T  P  V  AL
Sbjct:  195 RPNNKVRTTKYTLLSFLPRNLLEQFHRVANLYFIFIVLLNWFPAINAFGKEIAMIPVLFVLGVTAVKDLFEDRRRHASDKRVNNSTCRIYQSEAARYKKVLWKELRVGDLIHLSNNEVVPADILLLRTSAPNGVCYIDTGHLDGETNLKQREVPRTFLKKQEIFEPSKF-RSHIEVDAPTTKIYRFHGAMLHPSGAREV-VGTENLLLRECLLKNTDYVEGIVVYAGHETKAMLNNGGPRYKRSALERQMNQDVFWCVLVLVILCVIGAVGCKLWLQAYNQIKEPFKLEASSE-----STEAFLAFWTYIIILQIMIPLSLYVTLEMCKIIQVYHIHHNVDLYDTETDKRVECRALNITEELGQVQYIFSDKTGTLTENRMIFRRCTIAGVDYNHHNLENEGRGAKASAALSVIINPKLKEDLDSQLSEQSTIAQQRHAARIQEFLLLLAVCNTVVCSHHPHCDLMNASGVIEAVSNVFATSGSARLNSIDCTDRDGQMHSTNDKYERLKESRSVTPSPPLNSHTHNDSLRATHVP-SLTPINSVESSPNAEEIAQSCAIKSSFRPKLNISSLPFLGNKRNGNS--CNLTDEQKAKLNCSTTLFDSKPIFEAESPDELALVDAAYSYNCRLLKRNPGSV-IVDVPGEGILEYEILQVLPFDSYRKRMSIILRHPHTNEITVYCKGADSSILPNLAPIEDDSEQKQIINRTQQQLHTYASKGLRVLLMAKRILSFSEYTDWLAMHQEYQLLHEN---RDSKLRESYSMLERKLSLLGATGIEDRLQEGVPETLVSLVASGIVVWVLTGDKQETAINIAFSAKLFNSDMEILKIMARSKKAAEDTIKCYLTEIEECSESNGSDRRSQPSSSTSELLRRTRVNRKKYSRALVVDGKSLTYILDKRSNLTKHFLKLTTFCNSVLCCRATPLQKAYIVKVVKEELKMRTLAIGDGANDVSMIQTADVGIGISGQEGMQAVMAADFALSKFKYLERFLLVHGHWSYDRLARMVLYFFYKNAAFVFLIFWYQLYCGFSGAVMIDQMYLMLYNLLFTSLPPLAIGVYDQDSPEDLLRQKPYLYRKGRLGKVYRSFSFWLTLADALYQSLAIFFICVAVYMDTAIDIWEFGTTVTTICMFVMSCHVAIEIKSWTIIHVASIVIS-IGAFYVYSILYNSLC---VNCFGLPSTYWVIQHAIISPTYWLSTLLSIVIALLPRLVFLVIKNTISPDDVTRAL 1406          

Query:  109 ESRTIYPSVYHD-VDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLF----------------------HITRDLE----LYDDK---------VDKRCQVRATNITED-----LGQIQYIFCDKTGTLTENLMEFKRATI-----GFIDFYDDATESALTSDSQPISVLAKMLKK-------CHRNIEIDENL--------------------------DISIIEEFVLALAVCNTTMVSE-NKNESKIVV-----EIPVKSSASFFNSTHSTK--------------TNTLSNRRTSTGFNLSVFG---IQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQK-AFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNT--------SRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET---VLD------NIEKFCRKISKQQLANSDTSKYNNT--------------------LYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYML-LESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRK 3717
            ++RT++ ++ +D      N     ++NK+KTTKY +L+FIP NLFEQF RFAN+YF+ +  LNF P +++F  E A  P++F+L +TA+KD  ED RR +SD+ +NHM CL+Y+   + Y   YW++I  GDF+++  NE +PAD+L+  SS+    C+IETA LDGE NLKQRQ++      +    P+ +  S I  E PN ++ +F G ++   N +   L K NL+LRGC +RNT+   GIVIYAG+ETK++LNNN   +KRSKLE+Q+N DV WC+ IL+++C+  +IGH +WM  + +   V           +  +    LF T +I+FQ +IP+ L+V+IE+VK+ Q+F                      +IT DL     ++ DK         V +RC V     + D     +   Q +  ++   L+      +R ++     G +     +T+S   + S+  +  A +L K         +++  D  L                          D+  + +F +AL +CNT +VS  N+   K+ V     + PVK+   F      ++              TN  S++R  +    S      + +++    P+Q   Q    +P N                                 Y+ ++   P + ++    YE+ESPDE AL   A      L+ R P  V +   +  K  FEL  L    FDS RKRMSV++  P T  IT+Y KGAD+VI+ LI   T         R+++ K    + LY+ +GLRTL +AK+ LS++++  W  R    E  +   E  L      LE D+ LLGATGIEDRLQ+ VPE +  LR+             ETAINIAY+ KL +  +EI TL  ++QE    +LD        + FC   +    A +    Y                       ++  GL+++G+T++  LD+ +  K FL +A  C+SV+CCRSTP +K+ +V +V+  L+V TLAIGDGANDV+MIQ A VG+GI G+EGMQAVMASDFA+ +F+YL++LLLVHGH CY +LA M LY FYK+++ V + FW+Q   GFSGS MIDQ   I FNL  +  P LI G  DKD  +  L+  PQ+Y SG + + Y+P  FW N++D+ +QSLV F++ Y  +      +   G   +       +   L +E++ W+  +W S   S+ + +F      NS C      +  NPY  +   +  P  YL+  +    AL PR   + C  +  PS +    R+L  LP   R+
Sbjct:   31 KTRTVHSNILYDHAKGGDNPNRHYANNKIKTTKYTLLSFIPKNLFEQFHRFANVYFVFIALLNFVPVVNAFQPELALAPVVFILSVTAIKDLWEDYRRHRSDKEINHMDCLVYSRSERRYVEQYWKEIRVGDFIRLRCNEILPADVLLLSSSDPDRLCHIETATLDGETNLKQRQVVRSFIDLDTEFDPLKYN-SVIECEKPNNDLNRFRG-YITHRNGRRDGLYKDNLLLRGCTIRNTEEAVGIVIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFSAIGHGLWMYQYGDKRPVFDVLSPEGTDLSPVVSAIYLFLTMIIVFQVLIPISLFVSIEIVKICQVFFIHQDMELYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYSHDANARRIAMYQEMDSEEEECLSHGGTLPRRESLCSQHSGKVVLRSQSTKSHRRTGSRAEAKRASILSKHTAFSSPMEKDVTPDPQLLDKVNDCGSQMEFMRFHSQLLNQIPPDLCDVFDFFIALTICNTVVVSSPNQPRQKVRVRRFELKSPVKTIEDFIKRFTPSRLTSGSNSSSSSSLATNRSSSQRVCSSMLSSPSAESTLTKLDEERLPAQCLQQAFSPVPPN---------------------------------YDQDKASAPAECELR---YEAESPDEAALVYAARAYKCSLVGRLPDQVTVELPHLGKLTFEL--LHTLGFDSTRKRMSVVVRHPLTEQITVYTKGADSVIMDLIRPPTRDDSKGKRQRKVLYKTQNYLNLYAADGLRTLCIAKKVLSKEEYAGWLRRHLEAEAAIQGREELLFESALRLETDLHLLGATGIEDRLQDGVPETIAALRR-------------ETAINIAYACKLLDPEEEIITLNADSQEACAVLLDESLHYIQAKFFCSSSADPHAARAFQQDYTAVHFPAPPACSPASSGAPSTFLVHRLGLVIDGRTLAYALDKSLEDK-FLAVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFQYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMIDQWYLIFFNLMFSAFPQLITGTLDKDVSAETLQELPQLYMSGQNSEEYKPYMFWMNMIDAFYQSLVCFFIPYFMW------ICSPGAPPSLHSPSSPFCLHLGIETKTWTWMNWASIAFSIAL-FFTVALCYNSSCPTCY--SPSNPYWTIQRLLGDPLFYLLCIVTPIAALLPRYFYRICQGSLFPSPMLVG-RQLDKLPLEIRR 1310          

Query: 1888 FYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNT----SRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKIS---KQQLANSD--TSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPR 3624
             YE+ESPDE AL + A   G  LL R P  + +          +  L + PF S RKRMSV++  P TG + +Y KGADNVI+ L   +     SR++++K  ++++ Y++ GLRTL VAKR L E ++  W  R    E ++   E  LL   Q LE ++ LLGATGI DRLQEEVPE +E L++AGI +WVLTGDK ETA+NIA + KL     ++ T   +++E     + +  R IS   ++ L +    TS+    +  + L+++G+T+   L+ED+  K FL +  +C+SV+CCRSTP +K+ +V +V  +L V +LAIGDGANDV+MIQ A VG+GI G+EGMQAVM+SDFAI++FK+LR+LLLVHGH CY +LA M LY FYK+ + V + FWFQ   G+SGS M +    I FNL  T +PPL+ G+ DKD  +  L   PQ+YK+G + ++Y P  FW  ++D+ +QSLV F++ Y  Y  +++ +  FG   N S L++   + ++ESR  +  H +  +GS   A++    L+ SL  V  +  T NPY V    M  P  Y V  L T +AL PR
Sbjct:  691 LYEAESPDEAALVQAARAYGCTLLGRSPEQLLVALP-GTGPLSVPLLHLLPFHSARKRMSVVVRHPLTGQVVVYTKGADNVIMELAGTSAADGCSREIMEKTQQHLDNYAREGLRTLCVAKRALDEAEYEAWLKRHAFAETSIENREQLLLESAQRLETNLTLLGATGIVDRLQEEVPETIEALQRAGIKVWVLTGDKQETAVNIACACKLLRPTDQLLTANCDSKEACEARLYELQRDISTSIERGLPDRSAVTSEDQAAVSGFTLVIDGRTLDFALEEDL-QKLFLDVTGNCRSVICCRSTPLQKSQVVRLVGDSLGVMSLAIGDGANDVSMIQVADVGVGISGQEGMQAVMSSDFAISRFKHLRKLLLVHGHWCYTRLANMILYFFYKNVMYVNLLFWFQFFCGYSGSTMTNSWVLIFFNLLFTSVPPLLYGVLDKDVSANTLLSLPQLYKAGQNSQAYLPCTFWLTMLDAFYQSLVCFFIPYFAYADSDIGLFSFGSPINGSALLIILLHQVIESRTLTWIHAVVFLGS--AAFYYTFVLVFSLTCVTCNPPT-NPYGVETRAMSHPSYYFVCGLTTILALLPR 1273          

Query:   91 KESQVEESRTIYPSVYHDVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF 1353
            ++ Q ++ R + P   ++ +       K S NK++TTKY  L+FIP NLFEQ  RFAN+YFI +  LNF P +++F  E + +PI+ V+ +TAVKD  ED RR +SDR+VN++ C  Y+   + Y    W ++C GD V++  NE IPAD+++  SS+ +G C+IETANLDGE NLKQRQ++ +  ++    TP +F+ S I  E+PN ++ +F G ++   N   + L   NL+LR CI+RNT+ V GIV+YAG+ETK++ NN+   +KRSKLE+++N DV+W + IL+++C+  +IGH +W+  F +    +    +     + +L GF +FWT +I+ Q +IP+ LYV+IE+VKL Q++ I  DL+LY+ K+D   Q RA NITEDLGQIQY+F DKTGTLTEN M F+R T+   ++
Sbjct:   14 RDPQAKKRRVVVPEWVYNEEA-EGLQRKYSGNKIRTTKYTFLSFIPKNLFEQLHRFANVYFIFLAALNFVPIVNAFQPEISIIPIILVMSVTAVKDLWEDQRRRKSDRQVNNLLCDAYDRKQRRYVERRWAEVCVGDVVRLCCNEIIPADMVLLHSSDTNGVCHIETANLDGETNLKQRQVVRNLPQQGSEFTPENFS-SRIECENPNDDLRRFRG-YMEHPNKVKVGLHSENLLLRSCIVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNVDVLWSVVILLLMCLTAAIGHGLWLNSFEDHPVFLIPDDT-----HPALAGFYMFWTMIIVLQVLIPVSLYVSIEIVKLGQIYFIQNDLDLYNPKLDSGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVSGTEY 426          

Query: 1888 FYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNT----SRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKIS---KQQLANSD--TSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSC 3450
             YE+ESPDE AL + A   G  LL R P  + +          +  L + PF S RKRMSV++  P TG + +Y KGADNVI+ L   +     SR++++K  ++++ Y++ GLRTL VAKR L E ++  W  R    E ++   E  LL   Q LE ++ LLGATGI DRLQEEVPE +E L++AGI +WVLTGDK ETA+NIA + KL     ++ T   +++E     + +  R IS   ++ L +    TS+    +  + L+++G+T+   L+ED+  K FL +  +C+SV+CCRSTP +K+ +V +V  +L V +LAIGDGANDV+MIQ A VG+GI G+EGMQAVM+SDFAI++FK+LR+LLLVHGH CY +LA M LY FYK+ + V + FWFQ   G+SGS M +    I FNL  T +PPL+ G+ DKD  +  L   PQ+YK+G + ++Y P  FW  ++D+ +QSLV F++ Y  Y  +++ +  FG   N S L++   + ++ESR      ++SC
Sbjct:  721 LYEAESPDEAALVQAARAYGCTLLGRSPEQLLVALP-GTGPLSVPLLHLLPFHSARKRMSVVVRHPLTGQVVVYTKGADNVIMELAGTSAADGCSREIMEKTQQHLDNYAREGLRTLCVAKRALDEAEYEAWLKRHAFAETSIENREQLLLESAQRLETNLTLLGATGIVDRLQEEVPETIEALQRAGIKVWVLTGDKQETAVNIACACKLLRPTDQLLTANCDSKEACEARLYELQRDISTSIERGLPDRSAVTSEDQAAVSGFTLVIDGRTLDFALEEDL-QKLFLDVTGNCRSVICCRSTPLQKSQVVRLVGDSLGVMSLAIGDGANDVSMIQVADVGVGISGQEGMQAVMSSDFAISRFKHLRKLLLVHGHWCYTRLANMILYFFYKNVMYVNLLFWFQFFCGYSGSTMTNSWVLIFFNLLFTSVPPLLYGVLDKDVSANTLLSLPQLYKAGQNSQAYLPCTFWLTMLDAFYQSLVCFFIPYFAYADSDIGLFSFGSPINGSALLIILLHQVIESR---TLAFVSC 1245          

Query:  124 YPSVYHDVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF 1353
            Y + YH++            N ++TTKY +L+FIP+NLF+QF R AN+YF+ +V LN+ P + +F KE   +P+  VL + A KD +ED RR++ D+R+N+    +Y+   + Y    W ++C GD V++  NE IPAD+++  SS+ +G C+IETANLDGE NLKQRQ++ +  ++    TP +F+ S I  E+PN ++ +F G ++   N   + L   NL+LR CI+RNT+ V GIV+YAG+ETK++ NN+   +KRSKLE+++N DV+W + IL+++C+  +IGH +W+  F +    +    +     + +L GF +FWT +I+ Q +IP+ LYV+IE+VKL Q++ I  DL+LY+ K+D   Q RA NITEDLGQIQY+F DKTGTLTEN M F+R T+   ++
Sbjct:   60 YQAEYHNISK------GYQGNGIRTTKYTLLSFIPMNLFQQFHRAANLYFLFLVLLNWVPVVEAFQKEITMIPLAVVLIVIAFKDAMEDYRRYRYDQRINNTLTHVYSGKQRRYVERRWAEVCVGDVVRLCCNEIIPADMVLLHSSDTNGVCHIETANLDGETNLKQRQVVRNLPQQGSEFTPENFS-SRIECENPNDDLRRFRG-YMEHPNKVKVGLHSENLLLRSCIVRNTETVIGIVVYAGHETKAMQNNSGPRYKRSKLERRLNVDVLWSVVILLLMCLTAAIGHGLWLNSFEDHPVFLIPDDT-----HPALAGFYMFWTMIIVLQVLIPVSLYVSIEIVKLGQIYFIQNDLDLYNPKLDSGVQCRALNITEDLGQIQYLFSDKTGTLTENRMLFRRCTVSGTEY 456          

Query: 1831 NRYNVNQ----GKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKD-SIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCN-TDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQR 3714
            +R NVN+    G  P     L   YE+ESPDE AL   A   G  LL+R P  V + +  H K  +   L V  FD  R+RMS+I+  P T  I +Y KGAD+ I+                 ++++Y+++GLRTL  AK+ ++E+ +  W+ R +     +S  +  L+    ++E ++ LL ATGIEDRLQE VPE +  LR+AGI +WVLTGDK+ETA+NIAYS  L +    +FT           N E      SK++             +  GL+++G+T+S++LD+D+ T+ F+ L SHC+SV+CCR+TP +K+ +V++++  L+V TLAI DGANDVNMIQ A VG+GI G+EGMQAVMASDF+I++FK+L++LLLVHGH C  +LA M +Y FYK+    V + FW+Q+  GF+G+ MID    I FNL  T  PP++ GI D++  + +L + PQ+YK G     YR   FW  I+D+ +QS + F++ Y  Y+G+++ +   GI  NT  L     ++ +E + W+V HW+  VGS+LV +F      ++LC   + CN   +PY ++   M  P  YL+  L T +AL P   + +   T  PS   +A R++  LP  +R
Sbjct:  623 HRSNVNRRPRTGSSPAAP--LEVCYEAESPDEAALVHAAKAYGFTLLERTPDHVTV-RLPHGKELKFKVLDVLNFDPVRRRMSIIVRHPRTREIIMYTKGADSGIMEAAETQG----------DLDMYARDGLRTLCFAKKVVNEQTYSAWSIRRQEALAAISRKKELLMDTAADMENNLTLL-ATGIEDRLQENVPETIRALREAGIQVWVLTGDKLETAVNIAYSCMLLDHRDLVFTF----------NTE------SKRE-------------FSIGLVIDGRTLSLLLDDDLQTQ-FVELCSHCRSVLCCRATPLQKSRVVTLMRHRLKVMTLAI-DGANDVNMIQAADVGVGISGQEGMQAVMASDFSISRFKHLKKLLLVHGHWCSTRLANMIVYFFYKNVQAYVNLLFWYQLFCGFTGTAMIDYWFMIFFNLLFTSAPPIMFGIMDREISAFMLLQLPQLYKRGQQTGGYRRSTFWIGILDAFYQSFICFFIPYWAYEGSDVDIFTLGIPMNTVSLFTIILHLAIEIKSWTVVHWVIMVGSVLV-YFIVSLAFSALC---ISCNPPSDPYWLMQQQMADPIFYLICILTTVVALLP-YFLHALRGTLMPSDHLKA-RQIDQLPPHRR 1205          

Query:  178 SSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF--YDDATESAL 1380
            + N +KTTKY +  FIP NL EQF+R AN YF+++  LNF P +++F  + A +PI  +L LTA+KD  ED RR+QSDR++N  PCL+Y+   Q++    W+D+  GDFV++ +NE IPADIL+  +S+ +G C++ETANLDGE NLKQR+++           P +F  S ++ E PN  +  F+G   FE   K       +L+LRGC +RNT    GIV+YA +ETKS+LNNN+   KRSKLE+++N +V +   +L+I        HVIW++ FS +      +       + +L G  +F+T +IL Q IIP+ LY++IELVK+ Q++ IT+D++LYD++ D R Q RA NITEDLGQIQYIF DKTGTLTEN M F+R TI   ++   ++AT  AL
Sbjct:   42 AGNAIKTTKYTLWNFIPKNLIEQFRRVANAYFLSIAILNFVPSVNAFQPQVALIPICVILSLTAIKDAWEDFRRYQSDRKLNRRPCLIYSRSQQSFMERRWKDVKVGDFVRVLSNEIIPADILLLHTSDPNGVCHMETANLDGETNLKQRRVVPGFCDTNSTFEPQNFN-SIVVCEKPNDNLNHFSG---FEKGNKKTGFGIESLLLRGCTVRNTADASGIVVYA-HETKSMLNNNRPRNKRSKLERKMNIEV-FFCVLLLIFMCLIGAVHVIWLESFSTIPMYFIPNSDGTYTSS-ALSGVNMFFTMIILLQVIIPISLYLSIELVKMGQVYFITQDVDLYDEERDIRMQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGTEYPHSENATRLAL 437          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNEN-QEIFTLTG-----------NNQETVLD-NIEKFC--RKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCY------QGTELS-MAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQ 3711
            Y+++SPDE AL   A   G     R P  + +++      ++L  L +  F++ RKRMSVI+ +P+ G + LY KGAD +I  L+ + ++ +++    E++  ++  GLRTL +A + L E  F EW  +      +L+  E  L ALY+E+E  ++LLGAT IED+LQE VPE +  L  A I IWVLTGDK+ETA+NI YS  +  ++  E+F ++G           N +E ++  + ++F   + + K  +  SD+      + EY LI+ G +++  L+ D+  +  L +A  CK+V+CCR TP +KA +V +VK + +  TLAIGDGANDV+MI+TAH+G+GI G+EGMQAV+ASD++  +F+YL+RLLLVHG   Y ++     Y FYK+    LV FW+  L GFS   + DQ    LFN+  T LP L +G++D+D   +   R P +Y+ G     +  R F+   +  +  S V+F++ Y  +       G+ ++    F +   TSL+I     + L++ +W+  +     GSL V +FA +F +NS  +  +  +         +T+ Q   +LV+ L T +   P V M+       P+   + +R LQ    RQ
Sbjct:  452 YQAQSPDEGALVTAARNFGFVFRARTPETITLYEMGQFVTYQL--LAILDFNNVRKRMSVIVRNPE-GQLKLYSKGADTIIFDLLDQ-SNEELMYTTSEHLNEFAGEGLRTLALAYKDLDEDMFDEWMKKLLFASTSLNNREESLGALYEEIEEGLMLLGATAIEDKLQEGVPETISCLTLANIKIWVLTGDKLETAMNIGYSCNMLRDDMNEVFIISGHTLLEVQRELKNAKERIMGPSRDRFSSGQDVGKTDMYASDSVFEETIIAEYALIINGHSLAHALEADL-EQILLDVACLCKTVICCRVTPLQKAQVVELVKRHKRAVTLAIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSFAQFRYLQRLLLVHGRWSYHRMCNFLCYFFYKNFAFTLVHFWYGFLCGFSAQTVYDQWFITLFNIVYTSLPVLAMGLFDQDVNEQYSLRYPNLYRPGQLNLLFNKRKFFTCTLQGVCTSFVLFFIPYGAFLSAVRDDGSHITDHQSFAVTIATSLVIAVSVQIGLDTNYWTAVNHFFVWGSLAV-YFAILFAMNSDGIFRIFPSQFPFVGTARNTLNQKSVWLVILLTTVVCTMPVVAMRFLKTDLHPTQT-DKVRLLQQATRRQ 1073          

Query:  178 SSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVN-HMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQII 636
            + N +KT KY   TF+P+NLFEQF+RFAN YF+ ++ L   PEISS    T  +P++ VL +TAVKD  +D  R +SD++VN     +L     QN +   W ++  GD +K+  N+ + AD+L+  SSE  G CYIETA LDGE NLK RQ +
Sbjct:   45 ADNHIKTAKYTFYTFLPVNLFEQFQRFANAYFLVLLILQLIPEISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDQQVNTRQSQVLIKGKIQNEK---WMNVRVGDIIKLENNQFVAADVLLLSSSEPYGLCYIETAELDGETNLKVRQAL 195          

Query:  829 VEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIG---FIDFYDDATESALTSDSQP---ISVLAKMLKKCH-------RNIEIDENLDISIIEEFVLALAVCNTTMVSENKNESKIVVE 1557
            V  +  + G +TK + N  +  FKR+ +++ +N  V+W  G LI + I  SIG+ IW  +         +   ++ L +    GF+ FW+ +I+  T++P+ LYV++E+++L   + I  D ++Y  + D   + R T + E+LGQ+++IF DKTGTLT+N+M F + +I    + D YDD       ++  P    S    M +K H         I+++E L    ++EF   LA+C+T M  E ++E ++V +
Sbjct:  205 VSKLAEFNGLQTKLMQNCGRTKFKRTSIDRLMNTLVLWIFGFLICMGITLSIGNTIW--EQRVGRDFWAYLLWDKLLSSPVFSGFLTFWSYIIILNTVVPISLYVSVEVLRLGHSYFINWDRKMYYSRKDTPAEARTTTLNEELGQVEFIFSDKTGTLTQNIMVFSKCSINGKTYGDVYDDFGHKVDITEKTPCVDFSFNPLMDRKFHFHDSSLVEAIKLEEPL----VQEFFRLLALCHTVM-PEERSEGELVYQ 453          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMEL--------YSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLT------GNNQETVL------DNIEKFCRKISKQQLANSDT-------SKYNNTLY--EYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNT-DNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQ 3693
            YE+ESPDE AL   A      L+ + P  V I    H      D L V  FDS RKRMSV++  P T  + +Y KGADNVI+ ++   T     DK    M          Y+ +GLRTL +AKR L++ ++  W       E  +   E  L      LERDM LLGATGIEDRLQ+ VPE +  LR AG+ IWVLTGDK ETAINIA+S KL + + EI TL       G ++   L        + +    ++ +Q              +Y  T+     GL+++GKT+S  L++D+  + FL L   C+SV+CCRSTP +K+ +V +V+  L+V TLAIGDGANDV+MIQ A VG+GI G+EGMQAVM+SD+A+ +F++L +LLLVHGH CYD+LA M LY FYK++  V + FW+Q   GFSGS  IDQ   +LFNL    LPPL+ G+ DKD  +  L   P +Y++G +  +YRP  FW  ++D+++QS+V F+L YL Y+G+++ +  +G    T  L     ++ +E++ W+  HW S   SLL+ +F  +   N++C   ++C    NPY ++   M QP  YLV  +   +AL PR++ ++   +  PS   E LR  Q
Sbjct:  678 YEAESPDEAALVYAARAYNFTLVSKSPDQVII-DVPHVGRLTFDLLHVMAFDSTRKRMSVVVRHPLTDEMVVYTKGADNVIMDILKPCTGNSDKDKAKAKMHARTQADLNQYAMDGLRTLCIAKRELTDDEYATWAKSHLEAEAAIDCREEMLFESALRLERDMQLLGATGIEDRLQDGVPETIAALRDAGLQIWVLTGDKQETAINIAFSCKLLDASDEIITLNTESLSRGQHRHRTLCSLASTGGVRQAAEAVAPEQELERGGRGAVICDGRYRGTVVTTRRGLVIDGKTLSFALNKDL-EENFLKLTRDCRSVLCCRSTPLQKSMVVKLVREKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMSSDYAMPRFRHLHKLLLVHGHWCYDRLANMVLYFFYKNAAFVTLLFWYQFFCGFSGSSQIDQWYLMLFNLLFCSLPPLVTGVLDKDVSAETLLARPHLYQNGQNSLAYRPILFWVTMMDALYQSMVCFFLPYLAYRGSDVDIFTWGTPITTVSLFSILLHLAIETKTWTWIHWGSIALSLLL-YFLFVLAYNAIC---INCAAPSNPYMIMEILMTQPLFYLVCVVTPLVALLPRLVYRTLEGSCFPS---ENLRGRQ 1299          

Query:  151 VLSNFILKQS-------------SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTI-IPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF--YDDATESALTSDSQ 1395
            +LSN +L+++             SN +KTTKY + +F+P NLFEQF RFAN+YF+ +V LNF P +++F    A LP+ F+L +TAVKD  ED RR+ SDR +N+ PCL+Y    Q +    W+D+  GDF+K+  NE IPAD+L+  SS+  G C++ETANLDGE NLK RQ++      +    PM +T S +  E PN ++ KF G ++   N + + L K NL+LRGC +RNT++V GIV+Y G+ETK++LNNN   +KRSKLE+ +N D+IWC+ ILI++C+  +I H +WM  +         S    ++  + L GF +FWT +I+ Q + IP+ LYV+IE+VK+ Q++ I +D ELYD + D   Q RA NITEDLGQI+YIF DKTGTLTEN M F+R T+   ++   ++A   A   DS+
Sbjct:   26 ILSNILLEEAIDSGKENPNRAFASNAIKTTKYTVWSFLPKNLFEQFHRFANVYFVFIVLLNFVPVVNAFQPGLAVLPVAFILAVTAVKDLWEDYRRYHSDREINNAPCLVYCRAQQGFIERCWKDVRVGDFLKLRCNEIIPADVLLMASSDPDGLCHLETANLDGETNLKLRQLVKGFADLDCDFDPMKYT-SIVECERPNNDLNKFKG-FMLHSNERKVGLSKDNLLLRGCTVRNTEYVVGIVVYGGHETKAMLNNNGPRYKRSKLERNMNMDIIWCVIILIVMCLFIAIAHGLWMAGYEENPPFDVASKDGSHISPV-LSGFYMFWTMIIILQQVLIPISLYVSIEIVKIGQIYLIHQDEELYDPESDTPLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVAGKEYSHSNNAQRLAAYQDSE 453          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKN-TSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKY--------NNTLYEYGLILEG---------------------------KTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELS-------MAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLT 3651
            Y+++SPDE AL   A   G   L R    V I +   ++ +EL  L +  F+S+RKRMSVI+  P+ G + LYCKGAD VIL  + K+  +R+  +K   ++  ++   LRTL ++ + LSE+++L+W+ ++     +L+  E +   +Y+++E ++ LLGAT IED+LQ+ VPE +  L  A I IWVLTGDK ETA NI Y+  L  E+ +I    G+   T+L ++++ C+ I +    N +   +         N +   G  L G                           +    IL  + + K F++LA  C++V+CCR +P +KA +V MV  + Q  TLAIGDGANDVNMI+TAH+G+GI G+EGMQAV++SD++  +F++L RLLLVHG   Y ++ +   Y FYK+    LV FWF   NGFS   + D     L+N+  + LP L++G++D+D       + P++Y++G    ++  + F R ++  I  SL+IF++ Y  +  T  S          F ++  TSL ++    + L++ FW+  +  S  GS+ + +FA +F L+S  +  +  +        ++++KQP  +++      I +    +M   L+T
Sbjct:  514 YQAQSPDEGALVTAARNFGYVFLDRTLESVTIVELGTERVYEL--LNILDFNSDRKRMSVIVRSPE-GKLRLYCKGADTVILERLQKDDPNRESTEK---DLNTFAAESLRTLCLSYKDLSEEEYLDWSKKYEQASMSLTDREKKQGLVYEKIETNLKLLGATAIEDKLQDGVPEAIAKLAAAKIKIWVLTGDKQETAENIGYACHLLTEDMQI--CYGDEVSTMLSDVQE-CQTIKRDAKGNEEEVDFAKQFLKGKKNAIIITGGCLNGILTDNKQKRLDRLKLPRRRKPREQREEEKQREILKRERIEKRFVSLACACEAVICCRVSPRQKARVVRMVMKHKQAVTLAIGDGANDVNMIKTAHIGVGISGQEGMQAVLSSDYSFAQFRFLERLLLVHGRWSYLRMCKFLQYFFYKNFAFTLVHFWFSFFNGFSAQAVYDDWYITLYNMLYSALPVLVMGLFDQDVSDSKSFKFPELYETGQKNLNFNYKIFGRCLIQGIITSLIIFFIPYGAFLETMRSDGLAPDDYQSFAVVTATSLTLIVNLQIGLDTAFWTYLNTFSIFGSIAL-YFAIMFDLHSDGLHYIFPSNFKFTGTASNSLKQPYIFMLCIAHMVITILFLQVMHFGLIT 1133          

Query:  172 KQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQ---IIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIW--------MKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFY--DDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIE--------EFVLALAVCNTTMVSENKNE 1539
            +   N +KT KYNI+TF+P+NL EQF+R AN+YF+ ++ L   P ISS    T  +P++ VL +TA+KD V+D+ R +SD+++N+  C +  N S  ++   W +I  GD +++  N+ +PAD+L+  ++E +  CY+ETA LDGE NLK +Q   + H+    E ++      ++ I+ E+PN  + K+ G   ++D  K  +L    L+LRGC +RNT+   G+VI+AG +TK + N+ +  FKR+++++Q+N+ V    G+L+++    +IG+ IW         K  S ++        +   +     GF+ FW  +IL  T++P+ LYV++E+++L Q F I  DL +Y    D     R T + E+LGQI+YIF DKTGTLT+N+M FK+ +I  + F   +D   S       P+       ++  +N E  ++  ++++         EF   LA+C+T M  E + +
Sbjct:   44 RYKGNYIKTAKYNIVTFLPMNLLEQFQRVANVYFLFLLILQAIPIISSLAWYTTFVPLVIVLSITAIKDAVDDISRHRSDKQINNRKCEIMQNGS--FKEDKWMNIQVGDLLRLKKNDFVPADMLLLSTTEPNSLCYLETAELDGESNLKFKQALTVTHNNLTDEKQLAEF---DAIIMSEAPNNRLDKYLGTMQWKD--KMYSLDNDKLLLRGCRIRNTETCHGLVIFAGFDTKIMKNSGETKFKRTQIDKQMNKIVFMIFGMLLVMATGLAIGNTIWEVVHGQGFGKYCSGITGDPAVPSPDTVSEWAVWTGFLNFWGYIILLNTVVPISLYVSVEVIRLGQSFFINWDLRMYFKVNDTPSNARTTTLNEELGQIEYIFTDKTGTLTQNIMTFKKCSISGMAFGGCEDTWRSGHNVIDNPVD--WSWNERADKNFEFHDHSLVNLVRLKKDPTACEFFKLLALCHTVMAEEKEGD 511          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFN-ENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEY--------------GLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVN--MIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCY------QGTELS-MAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKRVDEESSNTIFDY 3789
            Y+++SPDE AL   A         R P  + + +    + ++L  L +  F++ RKRMSVI+ + + G + LYCKGAD+VI   +    ++Q+++   +++  ++  GLRTL +A R L E  F EW  R      +L   E  L A+Y E+E++M+LLGAT IED+LQE VPE +  L  A I IWVLTGDK        Y   L +   + +  +  ++  TVL  I     + S + L     S     L++               G +  G  ++V L   ++   FL   +   S V  R T   ++     V      + + + DG    N  +I+TAH+G+GI G+EGMQAV++SD++  +F++L+RLLLVHG   Y ++ +   Y FYK+    LV FWF    GFS   + DQ    LFN+  T LP L +G++D+D   +     P++Y+ G     +  R+F+  I   I+ S+V+F++ Y  +       GT LS      +  +TSL+IV    M L++ +W+  +     GS+ V +FA +F + S  +  +  +         +T+ QP  +LV+ L T + + P    +      RP++  +   R      R++K   L  L    R     S   F +
Sbjct:  461 YQAQSPDEGALVTAARNFDFVFRSRTPETITLHELGEPRTYQL--LAILDFNNFRKRMSVIVRNAE-GRLKLYCKGADSVIFERLHP-CNQQLVNITADHLSAFAGEGLRTLCLAYRDLDEASFEEWQERHHEANTSLQGREELLAAVYDEIEQNMMLLGATAIEDKLQEGVPETIAKLALANIKIWVLTGDKQAATRAAFYRSSLISIVRKNVHLILMSSLLTVLCFIHPINER-SVEPLHGVFISSTLGRLHKMAVVVMVVVIVADCAGRVCNGVNLAVRLGA-VLKDDFLAAVASNHSSVALRLTANSESENTRFVA----KQWIGLNDGRPSHNCIVIETAHIGVGISGQEGMQAVLSSDYSFAQFRFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGVFDQDINDQWSIDCPKLYEPGQLNLLFNKREFFICIGQGIYTSVVLFFVPYAAFVEAVRDDGTGLSDHQSLAVAVSTSLIIVVSLQMGLDTAYWTAINHFFIWGSVAV-YFAIMFAMYSAGLYSIFPSQFRFIGTARNTLNQPSVWLVIALTTIVCIMPIAAFRFLKTDLRPTLSDKTQERYMQRQRRKQKPQTL-RLHRVHRTGSRRSGYAFAH 1105          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLY-NNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXX-XXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIG---FIDFYD-DATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISI------IEEFVLALAVCNTTMVSENKNESKIVVE 1557
            +N++KT+KYN++TF+P+NLFEQF+R AN YF+ ++ L   P+ISS    T  +P++ VL +TAVKD  E+  R +SD +VN+    ++ N   QN +   W ++  GD +K+  N+ + AD+L+  SSE    CYIETA LDGE NLK RQ +    +    I  ++  +  +I E PN ++ +F G   +  N  S  L    ++LRGC+LRNT++  G+V++AG +TK + N+ +   KR+ +++ +N  V+W I   ++ +     +G+ IW  + +       +      + +    GF+ FW+ +I+  T++P+ LYV++E+++L   + I  D ++Y  K D   +VR T + E+LGQI+YIF DKTGTLT+N+M F + +I    +   YD    +  +   S P+     +L    R +  D+ +  +I      + EF   LA+C+T M  E K E ++  +
Sbjct:    1 TNRIKTSKYNVVTFLPVNLFEQFQRVANAYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDASEEYFRHRSDNQVNNRQSQVHINGKLQNEK---WMNVRVGDIIKMENNQFVAADLLLLSSSEPHSLCYIETAELDGETNLKVRQALPVTSQIADDIDKLAHFDGEVICEPPNNKLDRFTGTLYWRGNTYS--LDNDKMLLRGCVLRNTEWCYGLVVFAGPDTKLMQNSGRTKLKRTSIDRLMNTLVLWWIFGFLVCMGSILGLGNTIW--ESAIGYYFQPYLPWESAVDSAIFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYGKRDTPAEVRTTTLNEELGQIEYIFSDKTGTLTQNIMTFNKCSINGRVYGGAYDVTGHKVEINERSVPVDFSRNLLAD-RRFLFYDQTMLEAIRLGEWGVHEFFRLLALCHTVM-PEEKTEGELAYQ 462          

Query: 1888 FYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKIN-LQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQ 3213
             Y + SPDE AL       G     R      I  + + K+     L V  F S+RKRM++I+  P+  ++ L CKGAD+++   +S +   +++   V+++E Y+  GLRTLL+A++ LSE ++  +   +R+   ++   + ++  +   LE    ++G T IED+LQ++V + +  ++KAGI +WVLTGDK+ETAINI +S +L N+  E++ + G ++E                             L   G ++ G+++  I     +TK FL LA     ++ CR +P +KA IV ++  N   + TLAIGDGANDVNMI  AH+G+GI G EG QAV ASD+AI +FK+L+ LL VHG   Y + + +  Y FYK+ + V+  FWF   + FSG V  ++    +FN+  T  P +I  ++D+        +NP+
Sbjct:  368 LYNASSPDELALVNCGKYFGYFFKGRDDD-NNIEVEVNGKSVIYQLLGVIEFSSDRKRMTIIVRTPENKIMVL-CKGADSIVQARLSDS---KVLGATVQHLESYASGGLRTLLLAEKELSEAEYQNFKEEYRVAASSMIKRDEKMEEVADRLE----IVGTTAIEDKLQDDVDKAIFAMKKAGIKVWVLTGDKIETAINIGFSCQLLNDKMELYVIDGASKEG----------------------------LRTSGTVVSGESLFKIR----ITKQFLKLACSSSVLIACRMSPKQKADIVRLIIANNPSLITLAIGDGANDVNMINAAHIGVGISGVEGQQAVSASDYAIGQFKFLKNLLFVHGRESYRKNSYLVCYTFYKNVLFVMPQFWFGFYSAFSGQVFYEKWIYQIFNIIFTAFPIIIFALFDQQKSRHHFMQNPK 769          

Query:  319 GKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEK-REYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVI--WMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKN 1536
            G+ T  LP++FV+ ++AVKD  ED++R +SD   N    L  +  ++ + +  W+++  G  +++  ++  PAD+ + RS+  +G  Y+ET NLDGE NLK +  + D      +R T        +  E+PN     F G     DN  + +L  ++++LRG  LRNT++V GIVIY G+++K + N+++   K SK  +QI            IL  +  + H +   + +   ++T          L  IS      F T L+LF   +P+ L VT+E+VK         D E+YD   D    +   N+ E LGQ+ Y+F DKTGTLT NLME+K+ ++G   +  D  +     +       A M  K H N +         I+ F+  LA+C+ T+V+E K+
Sbjct:    1 GQPTILLPLMFVITVSAVKDIFEDMKRHKSDNVENTRKVLRLDKKTKTFVLDSWKNLRVGQIIQVRQDQYFPADLALLRSANNNGIAYVETKNLDGETNLKHKAAVVDASACTTFRGT--------LTCEAPN----DFEGTVKTADNV-TYSLDHNSILLRGTSLRNTEWVYGIVIYTGHDSKIMKNSSKSRTKFSKTNKQI------------ILSFSLLVLHSMNSGLSELVKLTTHTSTLLVRMTLTRIS-DSVTRFGTWLLLFANFVPISLIVTLEVVKF------LWDAEIYDVAKD----LNTKNLNEQLGQVDYVFSDKTGTLTCNLMEYKKHSVGKYSYGVDGAQITDGVEKDDEIFEAHMNDKNHPNYK--------NIQNFLTHLAICH-TVVAEAKD 364          

Query:  196 TTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPC--LLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFIL-FWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSV 1659
            T KYN LTF+P  L+EQF R AN++F+ +  L   PE+S  G+ T  +P++F+L + A+K+ +ED +R ++DR VN      +L N D   +    W+ +  GD ++I+  + +PAD+++  SSE    CYIETANLDGE NLK RQ +      +   + +S  +  I  E+PNR +Y F G    + +  ++ L    ++LRG  LRNTQ+V G+V+Y G++TK + N+ +   KRS +++  N  ++  +  L+++ +A +IG  IW           +        ++ +   F   F T +IL+  +IP+ L VT+E+VK  Q F I  D E+Y ++ +     R +N+ E+LGQ++YIF DKTGTLT N+MEFK+AT+  I  Y    E +      P      +L+  H N     +    +I EF++ ++VC+T               +P     S      S     L     S GF  +V
Sbjct:    2 TAKYNALTFLPRFLYEQFSRAANLFFLFIALLQQIPEVSPTGRYTTLMPLIFILVVAALKEIIEDYKRHRADREVNKKKTTQVLQNGD---WHTVSWEKVGVGDVLRITNGQNLPADLVMLSSSEPQAMCYIETANLDGETNLKIRQGLPLTAGLQTSDSLLSI-DGRIECEAPNRHLYDFTGNIQLQGHG-TVPLGPDQILLRGAQLRNTQWVFGVVVYTGHDTKLMQNSTRAPLKRSNVDRVTNLQILLLVVTLLLMALASAIGSSIWTS-------AHWKGDWYLGFRDNAPSNFGFNFLTFIILYNNLIPISLLVTLEVVKFIQAFFINWDSEMYHEESNTNAMARTSNLNEELGQVKYIFSDKTGTLTCNVMEFKKATVAGIA-YGHNEEPSEVGFQDP-----ALLQNLHSN-----HPSAGVIYEFLVMMSVCHTA--------------VPEAEDGSIVYQASSPDEGALVRAARSLGFTFTV 455          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNG 2214
            Y++ SPDE AL + A  +G     R P  V I     ++ FEL  L V  F S R+RMSVI+  P +G + LYCKGADN I   ++ N+  +  +  ++++EL++  G
Sbjct:  432 YQASSPDEGALVRAARSLGFTFTVRTPNMVVIDALGQEQNFEL--LHVLEFTSVRRRMSVIVRTP-SGKLRLYCKGADNAIYERLANNSLYK--EDTLQHLELFASEG 534          

Query: 1894 ESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDP-----DTGVITLYCKGADNVILPLISKNT---SRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKY----------NNTLYE-----------YGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQ--------GTELSMAEF-GILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLV--AW 3474
            +++SPDE AL  TA  +G   + +    + I     QK FE+  L +  F+S+RKRMS I+  P     D     L CKGAD++I   +S+ +   S  +++K   ++E Y+  GLRTL +A+R LS  ++ +WN ++ I   +L+  E EL  +   +ER++ILLG T IEDRLQ+ VP+C+E L +AGI +WVLTGDK+ETAINI +S  L N   E+  +     +T  D++++F  + S  ++ ++  SKY             ++E           Y ++++G  + + L  + + + FL L  +C++V+CCR +P++KAA+V +VK +L V TLAIGDG+NDV MIQ+A VGIGI G+EG QAVM SD+AI +F+YL RL+LVHG   Y +LA M    FYK+ I  L  FW+ + N F GS + +    + +NL  T LP + LGI D+D    +    PQ+Y+ GI  K +  R F   ++D ++QS++ F+  YL Y         G  L    F G+   T  +I    Y+LL    W  F  L    S LV  AW
Sbjct:  795 KAQSPDEAALVATARDVGFSFVGKTKKGLIIEMQGIQKEFEI--LNILEFNSSRKRMSCIVKIPGLNPGDEPRALLICKGADSIIYSRLSRQSGSNSEAILEKTALHLEQYATEGLRTLCIAQRELSWSEYEKWNEKYDIAAASLANREDELEVVADSIERELILLGGTAIEDRLQDGVPDCIELLAEAGIKLWVLTGDKVETAINIGFSCNLLNNEMELLVI-----KTTGDDVKEFGSEPS--EIVDALLSKYLKEYFNLTGSEEEIFEAKKDHEFPKGNYAIVIDGDALKLALYGEDIRRKFLLLCKNCRAVLCCRVSPSQKAAVVKLVKDSLDVMTLAIGDGSNDVAMIQSADVGIGIAGEEGRQAVMCSDYAIGQFRYLARLVLVHGRWSYKRLAEMIPEFFYKNMIFALALFWYGIYNDFDGSYLYEYTYMMFYNLAFTSLPVIFLGILDQDVNDTISLVVPQLYRVGILRKEWNQRKFLWYMLDGLYQSIICFFFPYLVYHKNMIVTSNGLGLDHRYFVGVYVTTIAVISCNTYVLLHQYRWDWFSGLFIALSCLVVFAW 1352          

Query:  472 SYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNG--KW--VFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATES-ALTSDSQPISVLAKMLKK-----CHRNIEIDENLDIS-------------------------------IIEEFVLALAVCNTTMVSENKNESK 1545
            +YW+ +  GD V+I  N+ IPADI++  +S+  G CY+ET NLDGE NLK RQ +            ++ T+  I  E P+  +Y + G  KW  + +   ++  +  +N++LRGC LRNT++  G+V++ G +TK +LN+     K+S++ +++N  V+    +L ILC    I + ++            F        + +  GF+ FW  +IL+Q+++P+ LY+++E++K  Q   I  D+ LY+ K+D  C  ++ NI++DLGQ++YIF DKTGTLT+N+MEFK+ TI  + +    TE+ A     Q I V  +  ++       R+  IDE   +S                                 E F+LALA+C++ +V  N +  K
Sbjct:  396 NYWKGVKVGDIVRIHNNDEIPADIILLSTSDTDGACYVETKNLDGETNLKVRQSLKCTNTIRTS-KDIARTKFWIESEGPHSNLYTYQGNMKWRNLADGEIRNEPITINNVLLRGCTLRNTKWAMGVVMFTGGDTKIMLNSGITPTKKSRISRELNFSVVINFVLLFILCFVSGIANGVYYDKKGRSRFSYEFGTIA---GSAATNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAAFIYGDVLLYNAKLDYPCTPKSWNISDDLGQVEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGIDVETEGRREKAEIAKDRDTMIDELRALSGNSQFYPEEVTFVSKEFVRDLKGASGEVQQRCCEHFMLALALCHSVLVEANPDNPK 790          

Query:   97 SQVEESRTIY---PSVYHDVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVN----HMPCLLYNNDSQNYEVSYWQ 483
            ++ +E RT+Y   P     +D   N I++   NK++TTKY  LTF+P N+  QF  FAN+YF+ ++ L  F          + +P++ ++ +TA+KD +ED RR   D  VN    H+   + N +     +S W+
Sbjct:  162 NRAQELRTVYYNMPLPKDMIDEEGNPIMQYPRNKIRTTKYTPLTFLPKNILFQFHNFANVYFLVLIILGAFQIFGVTNPGLSAVPLVVIVIITAIKDAIEDSRRTVLDLEVNNTKTHILEGVENENVSTDNISLWR 297          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQ-GTELSMA-------EFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQ 3693
            Y++ SPDE AL +    +G K + R P  V +  +   +  E   L +  F+S RKRMS I   PD G I L+CKGAD VIL  +  + + Q ++  + ++E Y+  GLRTL +A R +SE ++ EWN+ +      L     +L      +E+++IL+GAT IED+LQ+ VPE + TL++AGI IWVLTGD+ ETAINI  S +L +E+  +  +    ++    N+ +    +++ QL+  D     NTL    L+++GK++   L+ ++     LT+A  CK+V+CCR +P +KA +V MVK       LAIGDGANDV+MIQ AHVG+GI G EGMQA  ++D A+ +FK+L++LLLVHG   Y +++   LY FYK++ + +  FW+   N FSG  +++  +   +NL  T  PP ++G++D+   SR+LER PQ+YK G   + +    FW  I++  + S ++F  T L Y+ G  L+M         +G+   T+ +I+      L +  W+ F  ++  GSLL   F  IF      +      +   Y VV HT      +L + ++   AL    + K       P   Y  ++ +Q
Sbjct:  648 YQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLEETGEEKEYQLLNICEFNSTRKRMSAIFRFPD-GSIKLFCKGADTVILERLD-DEANQYVEATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIEKNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDMNLLIINEETRDDTERNLLEKINALNEHQLSTHDM----NTL---ALVIDGKSLGFALEPEL-EDYLLTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGISGMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYVFANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQFFSVYIFWGWIINGFFHSAIVFIGTILIYRYGFALNMHGELADHWSWGVTVYTTSVIIVLGKAALVTNQWTKFTLIAIPGSLL---FWLIFFPIYASIFPHANISREYYGVVKHTYGSGVFWLTLIVLPIFALVRDFLWKYYKRMYEPE-TYHVIQEMQ 1242          

Query:  127 PSVYHDVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTM 1518
            P V H  D L+N     S N + TTKYN  TF+P  LF++F ++AN++F+    +   P +S   + T    +L VL ++A+K+ +ED++R  SD+ +N+    +++    ++    W DI  GD +++ + E IPAD +I  SSE  G CYIETANLDGE NLK +Q   +  K    +  +      ++ E PN  +Y + G     D  + I L    +ILRG  LRNT ++ G+VI+ G+ETK L N      KR+ +E+ INR +I    +LI+L +  SIG+VI     ++   + +      N   +  + F+ FW   ILF  ++P+ L+VT+EL+K +Q F I  DL+LY +K D    VR +++ E+LGQI+YIF DKTGTLT N+MEFK  +I    + D   E    +    I V  +      + +    + D  II +F+  LA C+T +
Sbjct:  182 PRVIHINDSLANSSFGYSDNHISTTKYNFATFLPKFLFQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSDKELNNSTAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYIETANLDGETNLKIKQSRVETAKF-IDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLND--RQIPLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIALFTVLIVLILISSIGNVI--MSTADAKHLSYLYLEGTNKAGLFFKDFLTFW---ILFSNLVPISLFVTVELIKYYQAFMIGSDLDLYYEKTDTPTVVRTSSLVEELGQIEYIFSDKTGTLTRNIMEFKSCSIAGHCYIDKIPEDKTATVEDGIEVGYRKFDDLKKKLNDPSDEDSPIINDFLTLLATCHTVI 637          

Query: 1861 PYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDP-----DTGVITLYCKGADNVILPLISK-NTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQET---------VLDNI------EKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQ--------GTELSMAEF-GILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVV-------IVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPR 3624
            P KDD      +++SPDE+AL  TA Q+G   +      + +     QK F++  L V  F+S+RKRMS I+  P     D     L CKGAD+VI   + +      +++K   ++E Y+  GLRTL +A+R L+  ++  W   + +   +++  E EL  +   +ER++ILLG T IEDRLQ+ VP+ +  L +AGI +WVLTGDK+ETAINI +S  + N + E+  +  + ++          V++N+      EKF    S+++L  +   ++      + +I++G  + V L+ + + + FL L  +CK+V+CCR +P +KAA+V +VK  L V TLAIGDG+NDV MIQ+A VG+GI G+EG QAVM SD+AI +F+Y+ RL+LVHG  CY +LA M    FYK+ I  L  FW+ + N F GS + +      +NL  T +P ++L + D+D    V    PQ+Y+ GI  K +    F   ++D ++QS++ F+  YL Y         G  L    F G+      +     Y+ +E   W               WF  +F+  SL V            +++  YK       QP  + V+ +     L PR
Sbjct:  829 PNKDDPKKLDIKAQSPDESALVSTARQLGYSFVGSSKSGLIVEIQGVQKEFQV--LNVLEFNSSRKRMSCIIKIPGSTPKDEPKALLICKGADSVIYSRLDRTQNDATLLEKTALHLEEYATEGLRTLCLAQRELTWSEYERWVKTYDVAAASVTNREEELDKVTDVIERELILLGGTAIEDRLQDGVPDSIALLAEAGIKLWVLTGDKVETAINIGFSCNVLNNDMELLVVKASGEDVEEFGSDPIQVVNNLVTKYLREKFGMSGSEEELKEA-KREHGLPQGNFAVIIDGDALKVALNGEEMRRKFLLLCKNCKAVLCCRVSPAQKAAVVKLVKKTLDVMTLAIGDGSNDVAMIQSADVGVGIAGEEGRQAVMCSDYAIGQFRYVTRLVLVHGKWCYKRLAEMIPQFFYKNVIFTLSLFWYGIYNNFDGSYLFEYTYLTFYNLAFTSVPVILLAVLDQDVSDTVSMLVPQLYRVGILRKEWNQTKFLWYMLDGVYQSVICFFFPYLAYHKNMVVTENGLGLDHRYFVGVFVTAIAVTSCNFYVFMEQYRWD--------------WFCGLFICLSLAVFYGWTGIWTSSSSSNEFYKGAARVFAQPAYWAVLFVGVLFCLLPR 1436          

Query:  475 YWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPE--KREYRITPMSFTESHIIVESPNREIYKFNGKWVFED----NAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATES-ALTSDSQPISVLAKMLKK------------------------CHRNI-----EIDENLDIS-------IIEEFVLALAVCNTTMVSENKNESK 1545
            YW+++  GD V++  N+ IPAD+++  +S++ G CY+ET NLDGE NLK RQ +   +  K    IT   F    +  E P+  +Y + G + ++D    N ++  +  +NL+LRGC LRNT++  G+VI+ G++TK ++N      K+S++ +++N  VI    +L ILC    I + ++ K          F        + S  GF+ FW  +IL+Q+++P+ LY+++E++K  Q   I  D+ LY+ K+D  C  ++ NI++DLGQI+YIF DKTGTLT+N+MEFK+ TI  + +    TE+ A     Q + V ++  ++                        C  ++     EI E+L  S         E F+LALA+C++ +V  NK++ K
Sbjct:  442 YWKNVKVGDIVRVHNNDEIPADMILLSTSDVDGACYVETKNLDGETNLKVRQSLKCSKIIKSSRDITRTKF---WVESEGPHANLYSYQGNFKWQDTQNGNIRNEPVNINNLLLRGCTLRNTKWAMGMVIFTGDDTKIMINAGVTPTKKSRISRELNFSVILNFVLLFILCFTAGIVNGVYYKQKPRSRDYFEFGTIG---GSASTNGFVSFWVAVILYQSLVPISLYISVEIIKTAQAIFIYTDVLLYNAKLDYPCTPKSWNISDDLGQIEYIFSDKTGTLTQNVMEFKKCTINGVSYGRAYTEALAGLRKRQGVDVESEGRREKEEIAKDRETMIDELRSMSDNTQFCPEDLTFVSKEIVEDLKGSSGDHQQKCCEHFLLALALCHSVLVEPNKDDPK 835          

Query:   94 ESQVEESRTIYPSVYHDVDVLSNFILKQS---SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVN----HMPCLLYNNDSQNYEVSYWQ 483
            +++ +E RT+Y ++    D+L    L  +    NK++TTKY  LTF P N+  QF  FANIYF+ ++ L  F          A +P++ ++ +TA+KDG+ED RR   D  VN    H+   + N +     VS W+
Sbjct:  199 QNRSDELRTVYYNLPLPEDMLDEDGLPLAVYPRNKIRTTKYTPLTFFPKNILFQFHNFANIYFLILLILGAFQIFGVTNPGFASVPLIVIVIITAIKDGIEDSRRTVLDLEVNNTRTHILSGVKNENVAVDNVSLWR 335          

Query: 2038 PFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVK-INLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELS---MAEFGILCNT---SLLIVTYAYMLLESRFWSVFHW--LSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVV----NHTMKQPKTYLVVTLVTAIALFP 3621
            P D+   R   +  D DT +  L   G+D +IL          +I++ ++ ++ +S  GLRTL+ A + +   Q+  WN R+   + +L+  + ++     E+E  + LLG T IED+LQ+ V E +E +R+AGI +W+LTGDK ETAINI YS  L  +   +  LT  + E ++  +    +++    +A+              ++++G T+++          F+ L +   SV+CCR++P++KA +VS ++  +  + TLAIGDGAND+ MIQ+A +G+GI GKEG+QA   SD++I +F++L +LL VHG   Y + ++  L  FYK+         +Q    FSGS + +  S  +FN   T LP L +G+++KD +   L   P++Y  G   + +    F   ++ +   SL+I +L  + +  + LS   M   G++  T   +L+ V   ++ + +R W  F    LSC G L+  W   + +LN         NTD  Y V     NH  K   T+   +LV  +AL P
Sbjct:  985 PIDT---RKEGLQHDYDTEI--LEHIGSDELIL------NEEYVIERTLQAIDEFSTEGLRTLVYAYKWIDIGQYENWNKRYHQAKTSLTDRKIKVDEAGAEIEDGLNLLGVTAIEDKLQDGVSEAIEKIRRAGIKMWMLTGDKRETAINIGYSCMLIKDYSTVVILTTTD-ENIISKMNAVSQEVDSGNIAHC------------VVVIDGATMAMFEGNPTYMSVFVELCTKTDSVICCRASPSQKALMVSNIRNTDPNLVTLAIGDGANDIAMIQSADIGVGIAGKEGLQASRVSDYSIGQFRFLLKLLFVHGRYNYIRTSKFMLCTFYKEITFYFTQLIYQRYTMFSGSSLYEPWSLSMFNTLFTSLPVLCIGMFEKDLKPMTLLTVPELYSYGRLSQGFNWLIFMEWVILATTNSLIITFLNVVMWGMSSLSDNTMYPLGLINFTAIVALINVKSQFVEMHNRNWLAFTSVVLSCGGWLV--WCCALPILN---------NTDQIYDVAYGFYNHFGKDI-TFWCTSLV--LALLP 1487          

Query:  184 NKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTA-------------------------VKDGVEDLRR---------------WQSDRRVNHMPCLLYNNDSQ---------NYEV-----------SYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLK----KSNLILRGCILRNTQFVEGIVIYAGNETKSLLN--NNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATI 1338
            N++ +++Y   +F+P  L+ QF + AN YF  V  L   P  S+ G  T  +P+   + ++                          VKDG  D +                 +S    N+ P     N SQ         N+E+             W+ +  GDFV ++ ++ +PAD+L+      +  C++ET  LDGE NLK +Q   +  K     + ++   + + VE PN ++Y F G    +++     +K      N+I RG ILRNTQ V G+VI++G ETK  +N   N  T K  KL+++IN  +++ + ++  + +   +GHV+  K + + +   +   ++  +   ++  FI      I++ T+IPL LYVT+E++K+ Q   +  D+++Y  + +  C+ R   I E+LGQ+ YIF DKTGTLT+N M F++ ++
Sbjct:  141 NRITSSRYTFYSFLPRQLYAQFSKLANTYFFIVAVLQMIPGWSTTGTYTTIIPLCVFMGISMTREAWDDFRRHRLDKEENNKPVGVLVKDGNNDAQEVYTLPSSVVSSTAYLTKSAAAENNPPLNDDRNSSQGHFLDTHFNNFELLKNKYNVHIHQKKWEKLRVGDFVLLTQDDWVPADLLLLTCDGENSECFVETMALDGETNLKSKQPHPELNKLTKAASGLANINAQVTVEDPNIDLYNFEGNLELKNHRNDTIMKYPLGPDNVIYRGSILRNTQNVVGMVIFSGEETKIRMNALKNPRT-KAPKLQRKINMIIVFMVFVVATISLFSYLGHVLHKKKYIDQNKAWYLFQADAGVAP-TIMSFI------IMYNTVIPLSLYVTMEIIKVVQSKMMEWDIDMYHAETNTPCESRTATILEELGQVSYIFSDKTGTLTDNKMIFRKFSL 583          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWK-----DYHQKAFELDALCVFPFDSNRKRMSVIMMDPDT-GVITLYCKGADNVILPLISKN--TSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQ-EEVPECLETLRKA 2436
            Y+S SPDE AL   A  +G  +L R    + I       D   K    + L    F+S RKRMSV++  P+    + L CKGADNVI+  +      +++M D      E   K+    L++ +R+  E+   E       +  +LS+     L+L Q + + + +  +   +   Q + + + LET++K+
Sbjct:  758 YQSSSPDELALVTAARDLGYIVLNRNAQILTIKTFPDGFDGEAKLENYEILNYIDFNSQRKRMSVLVRMPNQPNQVLLICKGADNVIMERLHDRELAAKKMADICTSTKE--RKDAEAELVLQQRKSLERMVDEEAMARTSLRNSLSSVPRASLSL-QAVRKSLSMKNSRTRDPEKQIDSIDQFLETVKKS 945          

Query: 1864 YKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEK---QFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTG-NNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVI 3303
            ++DD L   Y++ SPDE A+ K    +G+ L +R    + +  ++  K    + L VFPF+S+ KRM +I+ D          KGAD V+  ++  N      D + E     ++ GLRTL++ +++L++K   QF +  N   +   N     ++++  Y  LE D+ LLG TG+ED+LQ++V   +E LR AGI IW+LTGDK+ETA  ++ S KL +  Q + T+T     E   + +E    KI++                   L+++G+++ + L      + F  +  H  +V+ CR TP +KA +  +++     R   IGDG NDV+MIQ A VG+GI GKEG QA +A+DF+IT+F +L  LLL HG   Y + A+++ ++ ++  II +    + + + F    +      + +    T  P   L + D D E  + +  P++YK     KS   + F+  ++ S++Q  VI
Sbjct:  583 FEDDELT--YQAASPDEIAIVKFTESVGLSLFKRDRHSISLLHEHSGKTLNYEILQVFPFNSDSKRMGIIVRDEQLDEYWFMQKGADTVMSKIVESN------DWLEEETGNMAREGLRTLVIGRKKLNKKIYEQFQKEYNDASLSMLNRDQQMSQVITKY--LEHDLELLGLTGVEDKLQKDVKSSIELLRNAGIKIWMLTGDKVETARCVSISAKLISRGQYVHTITKVTRPEGAFNQLEYL--KINRNAC----------------LLIDGESLGMFLKH--YEQEFFDVVVHLPTVIACRCTPQQKADVALVIRKMTGKRVCCIGDGGNDVSMIQCADVGVGIVGKEGKQASLAADFSITQFCHLTELLLWHGRNSYKRSAKLAQFVMHRGLIIAICQAVYSICSLFEPIALYQGWLMVGYATCYTMAPVFSLTL-DHDIEESLTKIYPELYKELTEGKSLSYKTFFVWVLLSLFQGSVI 1035          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYR----ITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVK---LHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFI-------DFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCN 1509
            SN+L   KYN +TF+P  L+EQFK F N+YF+ V      P +      +  +P+ FVL +T  K+ ++D++R + DR  N+    LY+  ++N  +   +D+  GD +K+   + IPAD+++ +SSE SG  +I+T  LDGE + K R  +  P  +       I  +S T S     +P + I+KF GK  ++D + S  L   N +    +L ++ F    V+Y G +T+  +N      K   LE +IN  +   +   +       +    +  D                        +I     LILF TIIP+ L V ++L K    HQ+ H         DK      VR + I EDLG+I+Y+  DKTGTLT+N M+ K+  +G +       D   D  +S ++S +  ++     L    +++          + + +L LA+C+
Sbjct:  172 SNELSNAKYNAVTFVPTLLYEQFKFFYNLYFLVVALSQAVPALRIGYLSSYIVPLAFVLTVTMAKEAIDDIQRRRRDRESNNE---LYHVITRNRSIPS-KDLKVGDLIKVHKGDRIPADLVLLQSSEPSGESFIKTDQLDGETDWKLR--VACPLTQNLSENDLINRISITAS-----APEKSIHKFLGKVTYKD-STSNPLSVDNTLWANTVLASSGFCIACVVYTGRDTRQAMNTTTAKVKTGLLELEIN-SISKILCACVFALSILLVAFAGFHND----------------------DWYIDILRYLILFSTIIPVSLRVNLDLAKSVYAHQIEH---------DKTIPETIVRTSTIPEDLGRIEYLLSDKTGTLTQNDMQLKKIHLGTVSYTSETLDIVSDYVQSLVSSKNDSLNNSKVALSTTRKDMSFR-------VRDMILTLAICH 577          

Query:  184 NKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATN------------------ITED--------LGQIQYI------FCDKTGTLTEN------------LMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEI----------DENLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFF----------------------NSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQE------TFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKF--YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILP----------LISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCR--KISKQQLANSDTSKYNNTLYE--------YGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPR 3624
            NK+KTTKY I +FIP NLFEQF RFANIYF+ +V LN+ P I++FGKE A LP++FVL +TAVKD  ED RR+ SD++VN+  C +Y++ S +Y  + W+D+  GD +K+S+NE IPADIL+  SS+ +  CY+ETANLDGE NLKQR++++   K + R +P +F    +  E+PN  IY+F+G  +  D++ ++ + K NL+LRGCI+RNT+ VEG+V+YAG++TK++LNN+    K SK+E+ +N DVI C+ IL  LC    +G  IW ++    +             +  ++GFI FWT +I+ Q +IP  LYV+ ELVKL Q+F I+ DL+LY ++ D+    RA N                  +TE+        +G + Y         D   + TE+            L + + A +GF+  +     S + S S  I    + + +   + ++          D    +S + EF + L++CNT +V+++          P ++++                         N +H+  T  +S  R     N+    +     P P   + ++       T N      +    +  SN SV S                 N++       D   ++   YE+ESPDE AL K AC  G +LL R P  V I+    +   +   L V  FDS RKRMSV++  P  G + +YCKGAD+ +L            +       ++++I  ++ +Y+++GLRTL +AKR LS+ ++ +W    +  E  L   E  L    Q+LE +M LLGATGIEDRLQ+ VPE +  LR+ G+ +WVLTGDK ETAIN+ Y+ KL + + +  TL   N++     I  +    KI     + S ++ Y    ++         GLI++G T+   L++ +  K FL LAS C+ V+CCR+TP +KA++V +V+  L+V TLAIGDGANDV+MIQ A VGIGI G+EGMQAVMASDFAI +F++L +LLLVHGH CYD++ +M LY FYK+++ VLV FW+Q+ NGFSGS  ID +S I FNL  T  PP++ GI DKD  + +L+ NPQ+YK+G   + Y  + FW  I+D+++QS+++F+  +L ++G        GI  + + +++   ++ L +  W+  H     GS+ +++   I       V  V   T   + V   TM   + + +  ++T  AL PR
Sbjct:   39 NKIKTTKYTIWSFIPKNLFEQFHRFANIYFLFIVGLNWVPAINAFGKEIAMLPLIFVLAVTAVKDLFEDRRRYNSDKKVNNTICQVYSSASASYIATKWKDVVVGDIIKLSSNEIIPADILLLNSSDENNICYVETANLDGETNLKQREVVNGLFKEDERFSPRNFN-FKLKCETPNNHIYRFHGA-IELDDSHTLAVGKENLLLRGCIVRNTKNVEGVVVYAGHDTKAMLNNSGPRSKHSKVERDLNLDVIACVVILFTLCFLGGLGCGIWTQNNDFFNAHFAPGGE----SSAPMEGFIRFWTFIIILQVLIPYSLYVSAELVKLGQVFLISSDLQLYHEETDQPVICRALNINEDLGQIKYVFSDKTGTLTENKMVFKKCTIGGVNYPHESAQDLPDAGPSDTEDEQYMQQVSSQVTLEKSRLAPLGFVALFGYHFPSPILSISCFIHCSLREMSELPYDADLAQVISGDSYKDNGSQLSFVREFFILLSICNTVVVNKHARPHPYQSGPPPRNTSEMHPSDKGINVRRQNYEERDLLSSPNVSHTPTTEEVSLGRGPLIVNVESGWVNNGLVPSPARPVQVERDPPNGFTGNSLSQSPVANRTRIPSNFSVDS-----------------NLDSSLLEIMDSKAWESISYEAESPDEAALVKMACSYGYRLLSRSPNSVTIFIP-GEGVVKFKVLHVLSFDSTRKRMSVVVRRPSDGAVLMYCKGADSAVLTRLTHASYADEAVEGGVKSTLVNQIDRHLTMYARDGLRTLCMAKRELSDSEYHDWLTEHKRAETALQHRERLLQESAQKLESNMELLGATGIEDRLQDGVPETIAKLREGGLKVWVLTGDKQETAINVGYASKLLDASMQKITLNAKNKDECSCQIYSWLNHLKIEPTVSSISGSTSYTTVSFDSRITADQPLGLIIDGPTLIYALEKPLNEK-FLHLASRCQVVLCCRATPMQKASVVELVRDGLKVMTLAIGDGANDVSMIQMADVGIGITGQEGMQAVMASDFAIARFRFLAQLLLVHGHWCYDRITKMILYFFYKNAMFVLVLFWYQLYNGFSGSNAIDDLSLIFFNLIFTAAPPIVCGILDKDLPATLLKDNPQLYKAGQEGQLYSRKLFWATILDALYQSVILFFACFLLFEGMPADDRMVGITMHQAAVVLASVHLGLMTAQWTWIHHFFLWGSVFLSFIWAI-------VFGVVQPTHKIHYVSLVTMATKEFWALCVMITVAALLPR 1257          

Query: 1456 NLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTG---FNLSV--FGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVR-TLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQ-------GTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLL 3495
            NLDI +        A+  T+ ++E   + K +          F + T +   N +  R+ + G   + LSV  F + + N  L  +     ++F+ P  L  L  +   +  SVI E   +          R   N  K           Y++ SPDE AL K A ++G     R P  V I     ++ +E+  L V  F+S RKRMSVI+  P+ G I LYCKGAD V+   + +N  +  ++  V+++E ++K GLRTL +A   L  +++ EW+  +     +L     ++    + +ER++ LLGAT IED+LQE VPE +  L  A I IWVLTGDK ETAINI Y+ +L     ++      N ET LD I ++  +  +    N    +     +   ++L+  T  + L+       FL LA  CK+V+CCR +P +K+ +V +VK +++   TLAIGDGANDV MIQ AHVG+GI G+EG+QA  ASD+AI +F+YL +LL VHG   Y +LA++ LY FYK+  + ++  WF + NGFSG ++ D+    ++N+  T +PPL +G++D+   S  + + P++YK+  + + Y  + FW  I+ S++ SL++F+L +   +       G  +     G +  T ++I       +E   W+    LS  GS + +WF  IFLL
Sbjct:  343 NLDIDMYYAPSDTPAMARTSNLNEELGQVKYI----------FSDKTGTLTRNVMEFRKVTIGGISYRLSVRPFFVLQNNDHLKNNSCGEGQSFSDPALLDNLREHHPTA--SVIREFLTLLSVCHTVVPERDTQNPDKI---------IYQAASPDEGALVKGAKKLGFSFNVRTPTSVIINAMGKEEVYEI--LNVLEFNSTRKRMSVIVRTPE-GKIKLYCKGADTVVFERMREN--QLYLETTVKHLEEFAKEGLRTLCIAMSELDPEEYSEWSKIYYQASTSLENRADKVDEAAELIERNLFLLGATAIEDKLQEGVPESIAALADADIKIWVLTGDKQETAINIGYACRLLTGEMKLLMC---NDET-LDGIREWLNEHLRMIGRNGIKCERMCCFFVDQVLLQALTDELKLN-------FLDLALCCKAVICCRVSPLQKSQVVRLVKHHVKDSITLAIGDGANDVGMIQAAHVGVGISGQEGLQAASASDYAIAQFRYLNKLLFVHGAWSYQRLAKLILYSFYKNVCLYVIELWFAMENGFSGQILFDKWCIGIYNVIFTSVPPLAIGLFDRTVSSESMLKYPKLYKTSQNAEIYNTKVFWLWIMTSVYHSLLLFYLPFGMLKHEVPYSNGLVVGQWHLGNVVYTLVVITVCLKAGMELDAWNWVCHLSIWGS-IASWF--IFLL 995          

Query:  181 SNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPC-LLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPE---KREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFIL-FWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFY-----------DDATESALTSDSQPIS--VLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVS-ENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEI 1677
            +NK+ T KYN LTF+P  L EQF R++N++F+ +  L     +S  G+ T  +P+L VL  +A+K+ +ED +R  +D  VN+    +L +N  Q+     W ++  GD VK+      PAD+++  SSE  G CY+ET+NLDGE NLK RQ+ +          +I+   + +  +  E PN  +Y F G  +     K + L    ++LRG  LRNTQ+V G+V Y G+++K + N+     KRS ++   N  +++  G+L+ L +  +IG  +W  +  +    + +       + +  Q + L F T +IL+  +IP+ L VT+E+VK  Q   I  D+++Y    D     R +N+ E+LGQ++YIF DKTGTLT N+MEF++ TIG I +            +D  ++    + Q  S   L   L++ H           S+I EF+  L+VC+T +   + +N  KI+ +       +      + K     N RT T   ++  G +E+
Sbjct:   15 NNKISTAKYNFLTFLPKFLLEQFSRYSNVFFLFIALLQQIDGVSPTGRYTTAVPLLLVLSCSAIKEIIEDYKRHAADGLVNNRRVKVLRDNTLQSL---LWIEVQVGDIVKVVNGHFFPADLILLSSSEPMGMCYVETSNLDGETNLKIRQMFNSLSLFIDCISKISGHCYLQGRVECEGPNNRLYDFVGN-IALTGKKPVPLSADQVLLRGAQLRNTQWVFGLVAYTGHDSKLMQNSTAAPIKRSNVDHTTNIQILFLFGLLMALALCSTIGFYVWAGEHEHAHWYLGY-------EELPPQNYGLTFLTFIILYNNLIPISLTVTLEVVKFIQAIFINLDIDMYYAPSDTPAMARTSNLNEELGQVKYIFSDKTGTLTRNVMEFRKVTIGGISYRLSVRPFFVLQNNDHLKNNSCGEGQSFSDPALLDNLREHHPT--------ASVIREFLTLLSVCHTVVPERDTQNPDKIIYQAASPDEGALVKG--AKKLGFSFNVRTPTSVIINAMGKEEV 511          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQ-EIFTLTGNNQETVLDNIEKFCRKI------------------SKQQLANSDTS-KYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKY----LRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCY 3327
            Y+++SPDE AL   A   G    +R P  + I     ++  EL  L +  F+++RKRMSVI+   D   I LYCKGAD++I   +  + +  ++DK  E++  ++  GLRTL++A + ++ + +  W +++      +   E ++ A+Y+E+E+++IL+GAT IED+LQ+ VP+ + TL  A I IWVLTGDK ETA+NI YS +L  ++  E+F + G++ + V ++I  +  K+                    ++ A SD+  K +     +GL++ GK++   L++ +  + FL LA  CK+V+CCR TP +KA +V +VK N +  TLAIGDGANDV+MI+ AH+G+GI G+EGMQA +ASD++  +F+Y    + RLLLVHG   Y ++ +   Y FYK+    L+  W+    G+S   + D      +N+  T  P + L I+D+D       R P++Y  G     +  R F  ++    + SL   WL +L Y
Sbjct:  481 YQAQSPDEAALVTAARNFGFVFKERSPTTLTIVAMGQEEQHEL--LAILDFNNDRKRMSVIVRQNDK--IKLYCKGADSIIYERLHPSCT-SLMDKTTEDLNKFAAEGLRTLVLAYKDITPQDYQAWKSKYDKACVAMDNREEQVQAVYEEIEKNLILIGATAIEDKLQDGVPDAIATLAAANIKIWVLTGDKPETAVNIGYSCQLLTDDMTEVFMINGDSMDAVRESINMYKSKVQAGLDDKAAHNNSVSFRKGSRETAKSDSGGKTDGGNAGFGLVITGKSLVFALNKQLELE-FLELACMCKAVICCRVTPLQKALVVQLVKDNKKAVTLAIGDGANDVSMIKAAHIGVGISGQEGMQATLASDYSFAQFRYPLHSIVRLLLVHGRWSYMRMCKFLNYFFYKNFAFTLIQLWYAFFTGYSAQTLYDAWFISFYNVLFTSGPVVFLAIFDQDVNHENCIRYPKLYVPGQQNIMFNKRVFAYSL---FYGSLTSLWLYFLAY 974          

Query:  184 NKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATI-------------------------------GFIDFYDDATESALTSDSQPISVLAKMLKKCH 1434
            N ++T+KY I+TF+P NLFEQF+R AN+YF+  V +   PEI++   E+  +P++FV+  TA+KD  +D+RR QSDR VN+        +S+  E   W  I  GD +KI  NE IPAD LI  +SE +G CYIETA LDGE NLK RQ + D  +       ++  +  +  E PN  + KFNGK  F++  +  +L   NLILRGC+LRNT +V G V+YAG ++K ++N+   TFKR+ L++ +N+ +I    +L  +CI  SIG  IW ++    +  VF  + N  + N+   G   + + +++  T+IP+ LY+++E++++ Q   I  D  +Y +K D   + R T +TE+LGQI+YIF DKTGTLT+N+M FK+ +I                               G   F+D A    + ++SQ    + ++L  CH
Sbjct:   26 NFIRTSKYTIITFLPKNLFEQFQRVANMYFLLQVIIMSIPEITALKPESTAVPLVFVIGFTAIKDAYDDIRRHQSDRDVNNRKSKALIGNSR--EEIKWMKIKCGDVLKIDNNEQIPADFLILSTSEENGLCYIETAELDGETNLKCRQPLPDTNEMGDDEALLAKFKGTVHCEPPNNILDKFNGKIAFDN--QEYSLDNDNLILRGCVLRNTDWVYGTVVYAGQDSKLMMNSGVSTFKRTNLDRLLNKLIIGIAVLLACICIVLSIGTTIW-EELVGQNFQVFLQWPNFYMNNVVFIGTCHWPSFIMVLNTLIPISLYISVEVIRMGQSIWINWDQYMYYEKKDTPARARTTTLTEELGQIEYIFSDKTGTLTQNVMTFKKCSIHGKMYGEHAPLLYCIVLQSPLVDFSSNPYYDGKFRFHDKALIDDIANNSQGCHEMMRLLALCH 468          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDN-IEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVR-TLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQG------------TELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCV---GSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKV 3549
            Y++ SPDE AL + A + GI  + RG     +       +     L V  FDS RKRMSVI+   + G   +  KGA+  IL  +         D   ++++ Y++ GLRTL VA+R  + +++ + + +     Q ++  E +L  +++E+E ++ LLGAT +ED+LQ  VPE +E +R+AGI +WVLTGDK +TA+NI++S   F    ++  +T  +  +  +  + +F +K+  Q           + L+  GLI++G ++  I +     + F+ +   C +V+CCR +P +KA +V +VK++ +   TLAIGDGAND  MIQ AHVGIG+ GKEG QAVM SD+AI++F++L R+LLVHGH  Y + A +  Y FYK+   +   F +   N FSG  +        +N+  T LP LI GI+++     +L+  P +Y+            F   +    W +LV F+  YL +QG              + +  FG       +IV+   + L + +W+   WL+ V   GS+L  +F    + NS      D  + + Y+V
Sbjct:  494 YQASSPDEKALVEAAVRFGI--VYRGKVGEDMEVQMQGTSHRYTLLHVLEFDSTRKRMSVIVKTAE-GQYLMLTKGAETAILDRLESGPK----DVTADHVDGYAEQGLRTLAVAQRVFTPEEYRDVDAKLTKAGQAINDREQQLAEVFEEVECNLHLLGATAVEDKLQAGVPETIEAMREAGIKVWVLTGDKEQTAVNISHSCGHFKHGMDLMFVTRRSSPSECEQELLQFKQKVQSQP----------DKLF--GLIVDGMSLVHIFNGH--KELFIEVCKFCMAVLCCRMSPLQKAQVVQLVKVSKEKPVTLAIGDGANDCGMIQEAHVGIGVMGKEGRQAVMTSDYAISRFRFLARVLLVHGHWYYIRSAILVQYFFYKNVCFITPQFIYAFFNAFSGQPLYHGFLLTCYNIFFTSLPILIFGIFNQHIGGDILQGRPSLYQDVAKNSRLSWVQFIYWVASGYWHALVFFFGGYLMFQGDLFDLLKPISILQNVGIWSFGTFVFAVCVIVSNLKLALVTHYWT---WLTHVVTWGSIL-TFFLFAIVFNSFQTTFGDQVSIDMYQV 1038          

Query:  106 EESRTIY-----PSVYHDVDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPC-LLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQII------HDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKS--ITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLD--------------ISIIEEFVLALAVCNTTMVSENKNESKI 1548
            EE RT+Y     PS   DV +      + + N + T+KY I  FIP NLFEQF+R AN YF+ +  +       S  K        +      V  G ED  R + D+ VN  PC ++++   ++ +    +DI  GD V++  NE  P D+++  S +  G C+I TANLDGE NLK R  +      H PEK       +S  ++ I  + P+ ++Y ++G+ +F  N ++   +L   NL+LRG  L+N+  V G+ +Y G ETK  LN  +   K S +E+ +N  +I  + +L++    C+     W +                + K + ++ F++F   LIL+  +IP+ LYVT+EL K         D+++Y+   D+      +++ E+LGQ++Y+F DKTGTLTEN M+FK  +I    + ++  E  +    QP S+L               +L               I  + +F LALA+C+T   S++ ++  I
Sbjct:    3 EEWRTVYVSNRYPSNDPDVAIKQK---RYADNMIVTSKYTIWNFIPKNLFEQFRRIANFYFLCIGTIQV--RGGSLIKSVVAGTDFY--HTKCVAKGYEDYLRHKVDKEVNSRPCGVVFDGIVKDIQS---KDIKVGDIVRVKDNEEFPCDLIVLASDDPEGKCHITTANLDGETNLKVRSAVSRTAFLHSPEK-------LSSLQATIECQHPHVDLYGYSGRIIFNANGENEITSLGPQNLLLRGARLKNSDHVFGVAVYTGKETKMALNQAEAPHKFSTVEKTMNTFLIVFLLVLVLQGAICTGLK-YWKESTVPGKAPYANDSGIASFKGV-IEDFLVF---LILYNYVIPISLYVTVELQKFIGALFFAWDVKMYNPDTDEPAIANTSDLNEELGQVEYVFTDKTGTLTENDMQFKECSINGKKYKENEMELCVDGPGQPASILMPSASVSLGQFNHVGHLQSTPFKTKMSILYNYIQDVLDFYLALALCHTVQASKSSDQESI 489          

Query: 2788 IVSMVKINLQVR-TLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQG-----TELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCV---GSLL 3465
            +V +VK++ +   TLAIGDGAND  MIQ AHVGIG+ GKEG QAVM SD+AI++F++L R+LLVHGH  Y + A +  Y FYK+   +   F +   N FSG  +        +N+  T LP LI GI+++     +L+  P +Y+            F   +    W +LV F+  YL +QG       + +  FG       +IV+   + L + +W+   WL+ V   GS+L
Sbjct:    7 VVQLVKVSKEKPVTLAIGDGANDCGMIQEAHVGIGVMGKEGRQAVMTSDYAISRFRFLARVLLVHGHWYYIRSAILVQYFFYKNVCFITPQFIYAFFNAFSGQPLYHGFLLTCYNIFFTSLPILIFGIFEQHIGGDILQGRPSLYQDVAKNSRLSWVQFIYWVASGYWHALVFFFGGYLMFQGDLFGSINVGIWSFGTFVFAVCVIVSNLKLALVTHYWT---WLTHVVTWGSIL 238          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVIL----PLISKNTSRQMIDKIV----ENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANS-----------------------DTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNT----DNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKD 3720
            YE+ESPDE AL   A      L+ R P  V + +  H      + L    FDS RKRMSV++  P T  IT+Y KGAD+VI+    P I+ N+  +   KI+      + LY+ +GLRTL +AK+ LS+ ++  W       E  +   E  L      LE ++ LLGATGIEDRLQ+ VPE + +LRKAG+ IWVLTGDK ETA+NIAY+ KL +  +E+ TL  ++QE     +E+    I  + L +S                        +   +++++  GL+++G+T++  LD  +    FLT+A  C+SV+CCRSTP +K+ +V +V+  L+V TLAIGDGANDV+MIQ A VG+GI G+EGMQAVMASDFA+ +F+YL++LLLVHGH CY +LA M LY FYK+++ V + FW+Q   GFSGS MIDQ   I FNL  +  P LI G  DKD  +  L++ PQ+Y SG + + Y+P  FW N++D+ +QSLV F++ Y  Y  +++ +  +G    T  L+    ++ +E++ W+   W++C   L +A+   +F   +LC     C T     NPY  +   ++ P  YL+ T+    AL PR   ++C  T  P+ V +  R+L  LP   R++
Sbjct:  681 YEAESPDEAALVYAARAYKCSLVGRLPDQVTV-ELPHLGKLNFELLHTLGFDSTRKRMSVVVRHPLTDQITVYTKGADSVIMELIRPPITGNSKGRRQKKILCRTQNYLNLYAADGLRTLCIAKKVLSKDEYARWLQHHLQAETAIQRREELLFESALRLETNLQLLGATGIEDRLQDGVPETIASLRKAGLQIWVLTGDKQETAVNIAYACKLLDPEEELLTLNADSQEACKLLLEESLHYIQAKFLCSSGDASAKDFHANVSSFEIYPSSPLSSHAASDSVHRLGLVIDGRTLAYALDASL-EDTFLTVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFRYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMIDQWYLIFFNLMFSSFPQLISGTLDKDVSAETLQQLPQLYTSGQNSEEYKPYMFWMNMIDAFYQSLVCFFIPYFAYTDSDVDLFTWGTPITTIALLTILLHLGIETKTWT---WMNC---LSIAFSVALFFTVALCYN-ASCPTCYPPSNPYWTIQRLLQDPVFYLLCTIAPVAALLPRYFYRACHSTLFPNPV-QVGRQLDKLPADTRRN 1315          

Query:   91 KESQVEES--RTIYPSVYHD-VDVLSNFILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDA 1365
            ++S+ +E+  RT++ +  HD      N   + ++N++KTTKY +L+F+P NLFEQF R AN+YF+ +  LNF P +++F  E A  P+LF+L +TA+KD  ED RR +SD  +NHM CL+Y+   + Y   YW+++  GDF+++  NE +PAD+L+  SS+    C+IETA LDGE NLKQRQ++      +    P+ +  S I  E PN ++ +F G ++   + K   L K NL+LRGC +RNT+   GIVIYAG+ETK++LNNN   +KRSKLE+Q+N DV WC+ IL+++C+  ++GH +WM  + +   V           +  +    LF T +I+FQ +IP+ L+V+IE+VK+ Q++ I +D +LYD++ D   Q RA NITEDLGQ+QYIF DKTGTLTEN M F+R T+  +++  DA
Sbjct:   21 RKSKAKETKTRTVHANTLHDFAKGEENPSRRYANNRIKTTKYTVLSFLPKNLFEQFHRLANVYFVFIALLNFVPVVNTFLPELALAPVLFILSVTAIKDIWEDYRRHRSDMEINHMDCLVYSRAEKGYVEKYWKEVRVGDFIRLRCNEILPADVLLLSSSDPDRLCHIETATLDGETNLKQRQVVRSFFDLDCDFDPLKYN-SVIECEKPNNDLNRFRG-YIIHQSGKKDALYKENLLLRGCTIRNTEEAVGIVIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFAALGHGLWMFQYGDKRPVFDVLSPEGTNLSPIMSAIYLFLTMIIVFQVLIPISLFVSIEIVKICQVYFIHQDADLYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYSHDA 446          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVE-NMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQE----TVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCN-TDNPYKVVNHTMKQPKTYLVVTLVTAIALFPR---VIMKSCLLTSRPSIVYEALRRLQ 3693
            YE+ESPDE AL   A   G  LL R P  V + +    +    + L    FDSNRKRMSV++  P TG   LY KGAD  I+ L+     ++ I    + +++ Y+K+GLRTL + K+ +S +++  W    +     +   E  ++A   +LE ++ LLGATGIEDRLQE VP+ +  LR+AGI +WVLTGDK ETA+NI Y+ +L  E   +  +T    +    ++LD   +  R+  +    N DT++      +  L+++G T+++ L  D+  + FL LA  C+SV+CCR TP +K+ +V +V+  L+V TLA+GDGANDVNMIQ A VGIGI G+EGMQAVMASDFAIT+FK+L++LLLVHGH C+ +LA M +Y FYK++  V + FW+Q   GFSG+ MID    I FNL  T  PP++ GI DKD  + +L   P++Y++G     Y  R FW +++D+ +QSLV F++ YL YQG+++ +  FG   NTS L +   ++ +E + W+V HW+  +GS+ + +F      +++CV    CN   NPY ++ + M  P  YL+  + T +AL PR    ++K+ +  S P I  + L R++
Sbjct:  621 YEAESPDEAALVYAAKTYGFTLLARTPNSVTV-RVPSGEELVFEVLDTLAFDSNRKRMSVLVRHPITGEYVLYTKGADYAIMELLGTPGQQKKIAADTQYHLDCYAKDGLRTLCITKKIVSSREYQSWLADRKRALAAIDGREELMMASAVQLETELTLLGATGIEDRLQESVPDTITALREAGIKVWVLTGDKPETALNIGYACRLMEEGDLVINMTSVVFQVTCVSILDCTLEEVRRYHEDP-RNVDTTQ------KISLMIDGDTLAIALSPDLQDR-FLDLAKRCRSVLCCRVTPLQKSRVVKLVRDKLKVMTLAVGDGANDVNMIQVADVGIGISGQEGMQAVMASDFAITRFKHLKKLLLVHGHWCHTRLANMIIYFFYKNAAYVNLLFWYQFYCGFSGTAMIDYWLMIFFNLFFTSTPPIMFGIMDKDVSAEMLMGVPELYRTGQGSGEYNFRTFWISMLDAFYQSLVCFFVPYLAYQGSDVDIFTFGTPLNTSSLFIILLHLGIEIKSWTVVHWIIMLGSVAL-YFIVTLAYSAICVT---CNPPSNPYWILQNQMADPMFYLICIISTVVALLPRYTFYVLKNSIAPS-PLIQAKHLDRME 1216          

Query:  184 NKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF 1353
            N +KT KY  L FIP+NL+EQF R AN+YF+ +  LNF P +++F  E A +PI  ++FLTA+KDG ED RR+QSD+++N+MPCL+Y+  +++Y    W+D+  GDFVK+  NE +PAD+L+  +S+ +  C+IET+NLDGE NLKQR  +           P SF  + ++ E PN  +  F   +V + + +       +L+LRGC +RNT+   G V+YAG+ETKS+LNNN   +KRSKLE+++N DV +C+ +L I+C+  S+GH +W+K+  +       S S  +L + SL  F +F+T +IL Q +IP+ LYV++ELVK+ Q+F I  D++LYD++ D + Q R+ NITEDLGQI+YIF DKTGTLTEN M F+R +I   D+
Sbjct:   49 NAIKTNKYTPLFFIPMNLYEQFHRLANVYFVGLAILNFIPVVNAFQPEVALIPICVIMFLTALKDGWEDFRRYQSDKKLNNMPCLIYSRTAKHYIERRWKDVRVGDFVKVVCNETVPADLLLLHTSDPNNVCHIETSNLDGETNLKQRNALPGLCTSNDVFEPESFNCT-VVCEKPNNNLNHFKC-FVEKPDKEKTGAGIESLLLRGCTVRNTEHAIGFVVYAGHETKSMLNNNGPRYKRSKLERRLNVDVFFCVLLLFIMCLIGSLGHYLWLKN-LSDVPSFLVSDSKGHLDSPSLSSFYMFFTMIILLQILIPISLYVSVELVKIGQIFFILTDVDLYDEETDSQVQCRSLNITEDLGQIEYIFSDKTGTLTENKMVFRRCSIMGKDY 435          

Query: 1456 NLDISIIEEFVLALAVCNTTMVSENKNESKIVVE--IPVKS-----------SASFFNSTHSTKTNTLSNRRTSTGF------NLSVFGIQEINPPLP-PSQITIQETFNIPKNLKMLETNKSD------SNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISK----NTSRQMIDKIVE----NMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLIL--EGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPS 3663
            NL+++ I +F LAL +CNT +VS       ++ E   P+KS           S S F +  + +  +     TS  F      +L+       +P  P P   + +ET ++   L M    + D       +K  + E  +       S  ++          +D++L   YE+ESPDE AL   A      L  R P  + + +     +  +  L V PFDSNRKRMSV++  P TG + +Y KGAD+VI+ L  +      ++++   I E    +++ Y++ GLRTL +AK+ L E+++  W  R  + E ++   E  LL   Q LE ++ LLG+TGI DRLQEEVPE +E L++AGI +WVLTGDK ETAINIA + KL   + ++ T   +N++     + +   ++   Q   S+  + + +    G IL  +G+T+   L ED+ + +FL L+  CK+V+CCRSTP +K+ +V +V+ +L+V TLA+GDGANDV+MIQ A VGIGI G+EGMQAVM+SDFAI +F  LR+LLLVHGH CY +LA M LY FYK+ + V + FW+Q   GFSGSVMI+    ILFNL  T +PPLI G+ D+D  +  LE +P++Y++    K Y P  FW  I+D+ +QS V F++ Y    G+++    FG   NTS L +   + ++ES   +  H L    S   ++FA + L ++ C+V    +  N   V    +  P  Y++  + T  AL PR++ +S   T  PS
Sbjct:  559 NLELTYITDFFLALTICNTVVVSSPGQPRHVMREARTPLKSLEELKVMFQRLSFSPFTTMSTPQMKSSPRGFTSRLFIRGKSGSLTFPTPTNNSPSCPNPGPESYEETSSLKVELNM-SAGRGDPIWADPDSKEALKEAQISSDRFKGSMEDQDEDGSSGEDSEDELL---YEAESPDEAALVHAARAYHCTLRARSPENLLV-ELPGIGSLPVRLLHVLPFDSNRKRMSVVVRHPLTGEVVVYTKGADSVIMDLAERPKGAEHAQELYSHIREQTQKHLDAYAREGLRTLCIAKKVLEEEEYDVWMKRQLLAESSIENREELLLESAQRLETNLTLLGSTGIVDRLQEEVPETIEALQRAGIKVWVLTGDKQETAINIANACKLLRSSDQLLTANCDNKDACAALLNELIVEVQCGQEGVSE-QREDPSSGSTGFILAIDGRTLDWALQEDLRS-SFLELSRKCKAVLCCRSTPLQKSKVVQLVRDHLRVMTLAVGDGANDVSMIQVADVGIGISGQEGMQAVMSSDFAIPRFHLLRKLLLVHGHWCYHRLANMILYFFYKNVMYVNLLFWYQFFCGFSGSVMINSWVLILFNLLFTSVPPLIYGVLDQDTAADALEEHPELYQTARSSKVYVPSIFWITILDAFYQSCVCFFIPYFALAGSDVESLSFGSPINTSALFIILLHQVIESHTLTWIHALVLFLS-AASYFAFVLLFSTFCIVC--SHPTNLLGVEPRQLSTPLFYVICAVTTVTALIPRILFRSLFNTVHPS 1320          

Query:  172 KQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF 1353
            K   N + TT+Y++LTFIP+NLF+QF RFAN+YF+ +  LN+ P + +F KE   +P+L VL +  +KD +ED RR+ SD++VN+    ++    ++Y    W+D+  GDFV++S NE IPAD+++  SS+  G CYIETANLDGE NLKQRQ++ D   ++ + +P +F  S I  E+PN ++ +F G ++   N   + L  SN++LR C +RNT+ V GIV+YAG+ETK+++NN+   +KRS LE+++NRD++WC+ +LI++C+  ++GH +W+K+  +    V          + +L  F +FWT +I+ Q +IP+ LYV+IE+VKL Q++ I  DL++Y+++ D R Q RA NITEDLGQIQY+F DKTGTLTEN M F+R +I  +++
Sbjct:   63 KYQGNAICTTQYSLLTFIPMNLFQQFHRFANLYFLFLALLNWVPVVEAFEKEITMIPLLVVLAVIGIKDALEDYRRYLSDKKVNNNMVEVFCGAQKDYVDCCWKDVRVGDFVRLSCNEIIPADMVLLYSSDPRGVCYIETANLDGETNLKQRQVVSDLPLQDSQFSPGNF-HSRIECENPNNDLNRFRG-FIEHANGVRVGLHSSNVLLRSCTIRNTETVIGIVVYAGHETKAMMNNSGPRYKRSLLERRLNRDILWCVALLIVMCLIAAVGHGLWLKNLKDPIFQVDGEM------SPALAAFYVFWTMIIVLQVLIPISLYVSIEIVKLGQIYFIHNDLDMYNEEQDSRIQCRALNITEDLGQIQYVFSDKTGTLTENKMVFRRCSIFGVEY 448          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVIL-----PLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLS-----ASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCN-TDNPYKVVNHTMKQPKTYLVVTLVTAIALFPR---VIMKSCLLTSRPSIVYEALRRLQ 3693
            YE+ESPDE AL   A   G  LL R P  V + +    +    + L    FDSNRKRMSV++  P TG   LY KGAD  I+     P       +++      +++ Y+K+GLRTL                      EQ++S       E  ++A   +LE ++ LLGATGIEDRLQE VP+ +  LR+AGI +WVLTGDK ETA+NI Y+ +L  E   +  ++      +LD   +  R+  +    N DT++      +  L+++G T+++ L  D+  + FL LA  C+SV+CCR TP +K+ +V +V+  L+V TLA+GDGANDVNMIQ A VGIGI G+EGMQAVMASDFAIT+FK+L++LLLVHGH C+ +LA M +Y FYK++  V + FW+Q   GFSG+ MID    I FNL  T  PP++ GI DKD  + +L   P++Y++G     Y  R FW +++D+ +QSLV F++ YL YQG+++ +  FG   NTS L +   ++ +E + W+V HW+  +GS+ + +F      +++CV    CN   NPY ++ + M  P  YL+  + T +AL PR    ++K+ +  S P I  + L R++
Sbjct:  605 YEAESPDEAALVYAAKTYGFTLLARTPNSVTV-RVPSGEELVFEVLDTLAFDSNRKRMSVLVRHPITGEYVLYTKGADYAIMELLGTPYAGDGQQKKIAADTQYHLDCYAKDGLRTL---------------------SEQHISFIWAYGREELMMASAVQLETELTLLGATGIEDRLQESVPDTITALREAGIKVWVLTGDKPETALNIGYACRLMEEGDLVTCVS------ILDCTLEEVRRYHEDP-RNVDTTQ------KISLMIDGDTLAIALSPDLQDR-FLDLAKRCRSVLCCRVTPLQKSRVVKLVRDKLKVMTLAVGDGANDVNMIQVADVGIGISGQEGMQAVMASDFAITRFKHLKKLLLVHGHWCHTRLANMIIYFFYKNAAYVNLLFWYQFYCGFSGTAMIDYWLMIFFNLFFTSTPPIMFGIMDKDVSAEMLMGVPELYRTGQGSGEYNFRTFWISMLDAFYQSLVCFFVPYLAYQGSDVDIFTFGTPLNTSSLFIILLHLGIEIKSWTVVHWIIMLGSVAL-YFIVTLAYSAICVT---CNPPSNPYWILQNQMADPMFYLICIISTVVALLPRYTFYVLKNSIAPS-PLIQAKHLDRME 1178          

Query:  184 NKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQ-IIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDF 1353
            N +KT KY  L FIP+NL+EQF R AN+YF+ +  LNF P +++F  E A +PI  ++FLTA+KDG ED RR+QSD+++N+MPCL+Y   +++Y    W+D+  GDFVK+  NE +PAD+L+  +S+ +  C+IET+NLDGE NLKQR   + +PE         SF  + ++ E PN  +  F   +V + + +       +L+LRGC +RNT+   G V+YAG+ETKS+LNNN   +KRSKLE+++N DV +C+ +L I+C+  S+GH +W+K+ S+V + +        L + SL  F +F+T +IL Q +IP+ LYV++ELVK+ Q+F I  D++LYD++ D + Q R+ NITEDLGQI+YIF DKTGTLTEN M F+R +I   D+
Sbjct:   61 NAIKTNKYTPLFFIPMNLYEQFHRLANVYFVGLAILNFIPVVNAFQPEVALIPICVIMFLTALKDGWEDFRRYQSDKKLNNMPCLIY---TKHYIERRWKDVRVGDFVKVVCNETVPADLLLLHTSDPNNVCHIETSNLDGETNLKQRNNDVFEPE---------SFNCT-VVCEKPNNNLNHFKC-FVEKPDKEKTGAGIESLLLRGCTVRNTEHAIGFVVYAGHETKSMLNNNGPRYKRSKLERRLNVDVFFCVLLLFIMCLIGSLGHYLWLKNLSDVPSFLVSDSKGH-LDSPSLSSFYMFFTMIILLQILIPISLYVSVELVKIGQIFFILTDVDLYDEETDSQVQCRSLNITEDLGQIEYIFSDKTGTLTENKMVFRRCSIMGKDY 436          

Query: 1891 YESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQ-EIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNN----------------TLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQ------GTELSMAE-FGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKD 3720
            Y+++SPDE AL   A   G     R P  + + +      ++L  L +  F++ RKRMSVI+ D   G + LYCKGAD +I  L+   +S  ++    E +  ++  GLRTL +A + L E+    W  +F  V   L   E +L ALY+E+ER M LLGAT IED+LQE VPE +  L  A I IWVLTGDK ETA+NI YS  +  ++  ++F ++G+     L  +++  R+  ++ L+ S  S   N                 + EY L++ G +++  L+  +    FL LA  CK+V+CCR TP +KA +V +V+ + +  TLA+GDGANDV+MI+T+H+G+GI G+EGMQAV+ASD++  +F+YL+RLLLVHG   Y +++    Y FYK+    LV FW+    GFS   + DQ    LFN+  T LP L +G++D+D   +   R+P +YKSG +   +  R F+   V  +  S ++F++ Y  +       G+  S  + F I   TSL+IV    + L++ +W+  + L   GSL + +FA +F + S  +  V  N  +      + + +   +LV+ L TA+ + P + ++S   +  P+   + +R+LQ     QR +
Sbjct:  487 YQAQSPDEAALVTAARNFGFAFWARTPESITVCEMGQVVTYQL--LAILDFNNTRKRMSVIVRDAQ-GRLRLYCKGADTIIFDLLDP-SSTDLMHTTSEQLNEFAGEGLRTLALAYKDLDEEYCDVWMKKFLFVSAVLENREDQLAALYEEIERGMKLLGATAIEDKLQEGVPETISKLNLANIKIWVLTGDKQETAVNIGYSCNMLRDDMTDVFVVSGHT----LTEVQQQLREAKERILSLSRVSDARNDEENDMFADDSVFEEAIITEYALVINGHSLAHALEPQLEI-VFLDLACLCKTVICCRVTPMQKAQVVELVRKHKRAVTLAVGDGANDVSMIKTSHIGVGISGQEGMQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMSNFLSYFFYKNFAFTLVHFWYGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGLFDQDVNDQNSLRHPSLYKSGQNNLFFNKRQFFLCTVHGMTTSFLLFFIPYGAFSVMVKEDGSHSSDQQTFSITIATSLVIVVSVQIGLDTHYWTAVNHLFVWGSLAM-YFAILFAMQSDGLFGVFSNIFSFVGAARNCLSEKSVWLVILLTTAVCIVPDLFVRSIRASLFPTQT-DKVRQLQQSCKSQRPE 1109          

Query:  178 SSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIG---FIDFYD------DATESALTSDSQPISVLAKMLKKCHRN--IEIDENLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHS 1602
            + N++KT+KYNI TF+P+NLFEQF+R AN YF+ ++ L   PEISS    T  +P++ VL +TAVKD  +D  R +SD++VN+    +    S   E   W ++  GD +K+  N+ + ADIL+  SSE  G CYIETA LDGE NLK RQ +            ++F +  +I E PN ++ KF G   +  N  S  L    ++LRGCILRNT++  G+VI+AG +TK + N  +  FKR+ +++ +N  V+W    LI + +  + G+ IW  +         F    +   +    GF+ FW+ +I+  T++P+ LYV++E+++L   F I  D+++++ + +     R T + E+LGQ+++IF DKTGTLT+N+M F + +I    + D YD      + TE     D    ++L+    K + N  +E  +  D + ++EF   LA+C+T M  E  +E K+V +      A+   +  +
Sbjct:   29 ADNRIKTSKYNIFTFLPVNLFEQFQRVANAYFVVLLILQLIPEISSLSWFTTIVPLVMVLVITAVKDATDDYFRHKSDQQVNNRKSQVLIRGSLQKE--KWMNVRVGDIIKLENNQFVAADILLLCSSEPYGLCYIETAELDGETNLKARQALSVTSDLGDVSKLLNF-DGKVICEPPNNKLDKFTGTLNWRGNKYS--LDNGKMLLRGCILRNTEWCFGMVIFAGLQTKLMQNCGKTKFKRTTIDKLMNTLVLWIFAFLICMGVILATGNTIW--ETWIGRGFEMFLPWTKFQISTVFSGFLTFWSYIIILNTVVPISLYVSVEVLRLGHSFFINWDVKMHNRQTNTAAVARTTTLNEELGQVEFIFSDKTGTLTQNIMVFSKCSINGTIYGDVYDEFGHRMEITEKTACVDF-SYNLLSDGAFKFYDNTLVEAVKQKDPA-VQEFFRLLALCHTVMSEE--SEGKLVYQAQSPDEAALVTAARN 503          

Query:  745 VFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKRVDEESSNTIFDYLKFNANKSKEECQESTYFSFLKGNKILPSNVQDTNNSAVIA 3912
            VFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVIWCIGILIILCIACSIGHVIWMKDFSNVSTVVFFSFSNENLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLD+SIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGSLIQKSSSISKLNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALC+FPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKRVDEESSNTIFDYL+FNANKSKEECQESTYFSFLKGNKILPSNVQDTNNSAVIA
Sbjct:   47 VFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVIWCIGILIILCIACSIGHVIWMKDFSNVSTVVFFSFSNENLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDMSIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGSLIQKSSSISKLNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCIFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKRVDEESSNTIFDYLRFNANKSKEECQESTYFSFLKGNKILPSNVQDTNNSAVIA 1102          

Query:  745 VFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKRVDEESSNTIFDYLKFNANKSKEECQESTYFSFLKGNKILPSNVQDTNNSAVIA 3912
            VFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVIWCIGILIILCIACSIGHVIWMKDFSNVSTVVFFSFSNENLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLD+SIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGSLIQKSSSISKLNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALC+FPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKRVDEESSNTIFDYL+FNANKSKEECQESTYFSFLKGNKILPSNVQDTNNSAVIA
Sbjct:   21 VFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVIWCIGILIILCIACSIGHVIWMKDFSNVSTVVFFSFSNENLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDMSIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPSQITIQETFNIPKNLKMLETNKSDSNKSVISEGSLIQKSSSISKLNRYNVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCIFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQRKDADLGNLESNKRVDEESSNTIFDYLRFNANKSKEECQESTYFSFLKGNKILPSNVQDTNNSAVIA 1076          

Query:   85 CCKESQV-EESRTIYPSVYHDVDVLSNFIL------KQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSIT-LKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPS-QITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYK---DDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSR--QMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISK-----QQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQ---------RKDAD----------LGNLESNKRVDEESSNTIFDYLKFNANKSKEECQESTY-FSFLK--GNKILPSNV 3882
            CCK S++ +E+  IYPS         NF +      K+ +N+++TTKY    FI LNLFEQFKR++N++FI  V LNF PE+ +F + TA +PILF+L +T +KDGVEDLRR+ SDR VN+ P L Y+     + V  W+DI  GD +K+S+ E IPAD+LI+ SS+ SG C+IET ++DGE  LKQR ++   +     +  + F   +  VE+ N++IYKFNGK       KS+  L  +NLILR  ILRNT  V GIVIYAGN+TK  +NN Q  FKRS LE Q+N D++ C+GILII+CI   IG   +++ F+ +  V+F + +   + ++ LQGFI FWT +I+FQ+IIP+ LY+T+ELVK HQ+ HIT DL LYD+ +DK+  V+A NITEDLGQI+ +FCDKTGTLT+N M F+ A+I   ++  +  +  L  D++              N E+  N  I    + +L  A+CNTT+++++    K +V +         +S  ++ TN      TSTG  +  F    ++ P+ P   I+I++T  IPK+L      K++S +SV S               + N+     P++   ++ L     SESPDE AL +     G  L QR    + IW  + +K    + L   PFDS RK MSVI+ D  TG I+L CKGAD+V+ P I  N+ +  ++I++   ++  Y+ NGLRTL++ KR L+E ++ +W      VE NL  +E+E+  LY  +E ++ L+GA G+ED+LQE VPE LE  ++AGINIW+LTGDK ETAI+IAYS +LF++N+ +  ++  ++  +++ + +    I K     ++  N  T K+     E+ L+++G ++SVIL  D + + FL +A  C  VVCCR TP +K  +V +VK   +VRTLAIGDGANDVNMIQTA +GIG+ GKEG QA +ASDFAITKFKYL+RL+LVHGH  YD+LARMSL MFYK+ II LV F++Q+L+GFS S  IDQ++Q++F+L  TGLPP+I G+WDKDF   +L  NPQIY +GI+ K YRPRDFWR I+DS+WQSLVIF +  LCY  TE+SM EFGI+  + ++I  ++++++ESR WSVFHW  C+G+L + ++ E+F+LNSLCVV++DCNTDNPYKV+++TM + KTYL++ L TAI+LFPR+++K  L+ SR S+ YEA RR+  L  R+         + D            LGNLE  K+            LK +  + +E   +  Y FSF K   N++LP N+
Sbjct:    4 CCKISKIHDENVNIYPS---------NFYIPLTDESKKLNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNLTNLEEV-FKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDNE--------------NEELHNNPHIL---QLLLLSAICNTTIIAKSNQREKKLVHV---------DSCSTSLTNV-----TSTGGKIQSFFDYGVSLPIEPILPISIEDTDPIPKDLIKAVFEKAESLQSVNS-------------YPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRILNENEYKKWEETLSKVEDNLINNESEIKELYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKEISCESESEIINVMSQIREDIEKSLFNSKRENNEKTCKHK----EFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGEVVYLVKKYYEVRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNLEEFKK------------LKCDKCQFRENFIDKQYPFSFAKYRKNQVLPLNL 1240          

Query:   85 CCKESQV-EESRTIYPSVYHDVDVLSNFIL------KQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSIT-LKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXXXXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFYDDATESALTSDSQPISVLAKMLKKCHRNIEIDENLDISIIEEFVLALAVCNTTMVSENKNESKIVVEIPVKSSASFFNSTHSTKTNTLSNRRTSTGFNLSVFGIQEINPPLPPS-QITIQETFNIPKNLKMLETNKSDSNKSVISEGXXXXXXXXXXXXNRYNVNQGKCPYK---DDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSR--QMIDKIVENMELYSKNGLRTLLVAKRR------------------------LSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISK-----QQLANSDTSKYNNTLYEYGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEALRRLQNLPWRQ---------RKDAD----------LGNLESNKRVDEESSNTIFDYLKFNANKSKEECQESTY-FSFLK--GNKILPSNV 3882
            CCK S++ +E+  IYPS         NF +      K+ +N+++TTKY    FI LNLFEQFKR++N++FI  V LNF PE+ +F + TA +PILF+L +T +KDGVEDLRR+ SDR VN+ P L Y+     + V  W+DI  GD +K+S+ E IPAD+LI+ SS+ SG C+IET ++DGE  LKQR ++   +     +  + F   +  VE+ N++IYKFNGK       KS+  L  +NLILR  ILRNT  V GIVIYAGN+TK  +NN Q  FKRS LE Q+N D++ C+GILII+CI   IG   +++ F+ +  V+F + +   + ++ LQGFI FWT +I+FQ+IIP+ LY+T+ELVK HQ+ HIT DL LYD+ +DK+  V+A NITEDLGQI+ +FCDKTGTLT+N M F+ A+I   ++  +  +  L  D++         ++ H N  I          + +L  A+CNTT+++++    K +V +         +S  ++ TN      TSTG  +  F    ++ P+ P   I+I++T  IPK+L      K++S +SV S               + N+     P++   ++ L     SESPDE AL +     G  L QR    + IW  + +K    + L   PFDS RK MSVI+ D  TG I+L CKGAD+V+ P I  N+ +  ++I++   ++  Y+ NGLRTL++ KR                         L+E ++ +W      VE NL  +E+E+  LY  +E ++ L+GA G+ED+LQE VPE LE  ++AGINIW+LTGDK ETAI+IAYS +LF++N+ +  ++  ++  +++ + +    I K     ++  N  T K+     E+ L+++G ++SVIL  D + + FL +A  C  VVCCR TP +K  +V +VK   +VRTLAIGDGANDVNMIQTA +GIG+ GKEG QA +ASDFAITKFKYL+RL+LVHGH  YD+LARMSL MFYK+ II LV F++Q+L+GFS S  IDQ++Q++F+L  TGLPP+I G+WDKDF   +L  NPQIY +GI+ K YRPRDFWR I+DS+WQSLVIF +  LCY  TE+SM EFGI+  + ++I  ++++++ESR WSVFHW  C+G+L + ++ E+F+LNSLCVV++DCNTDNPYKV+++TM + KTYL++ L TAI+LFPR+++K  L+ SR S+ YEA RR+  L  R+         + D            LGNLE  K+            LK +  + +E   +  Y FSF K   N++LP N+
Sbjct:    4 CCKISKIHDENVNIYPS---------NFYIPLTDESKKLNNRIRTTKYRFYNFIFLNLFEQFKRYSNLFFIFCVILNFIPEVGAFNQGTAIIPILFILIVTLIKDGVEDLRRYFSDRNVNNRPVLRYDKMLNEFCVCKWKDISVGDMIKLSSCERIPADLLIYYSSDPSGMCFIETMDIDGETTLKQRFVMKSLDNNLTNLEEV-FKNYYFEVEASNKQIYKFNGKIFDHRIGKSVQHLNCTNLILRDTILRNTNEVRGIVIYAGNQTKVFMNNKQARFKRSLLEDQLNVDMLMCLGILIIVCIMTGIGCSFYLRGFNKIQNVIFITSNFTVIYDVYLQGFIQFWTGIIVFQSIIPIALYITLELVKAHQILHITNDLALYDESMDKKIDVKAYNITEDLGQIKQMFCDKTGTLTDNEMIFRNASIFGKNYKTEENDLRLCCDNEN--------EELHNNPHI---------LQLLLLSAICNTTIIAKSNQREKKLVHV---------DSCSTSLTNV-----TSTGGKIQSFFDYGVSLPIEPILPISIEDTDPIPKDLIKAVFEKAESLQSVNS-------------YPKSNITADNFPHRHLTNEELSPLILSESPDEDALVRMVMYNGFALHQRTRDKLIIWNAFKRKWIVYEILKTLPFDSIRKCMSVIVKDNATGEISLNCKGADSVMFPKIIANSDKDFEIINQTKADIYAYASNGLRTLVMGKRVSNLHKINVFNAIIEGKSNNNIIWILNENEYKKWEETLSKVEDNLINNESEIKELYDLIESNLDLVGAIGLEDKLQEFVPEILECFKEAGINIWILTGDKKETAISIAYSTRLFSQNETVKEISCESESEIINVMSQIREDIEKSLFNSKRENNEKTCKHK----EFVLVIDGCSLSVILTSDELKEEFLHIAYFCNCVVCCRCTPIQKGEVVYLVKKYYEVRTLAIGDGANDVNMIQTADIGIGVSGKEGSQATLASDFAITKFKYLKRLVLVHGHCSYDKLARMSLIMFYKNMIISLVMFFYQILSGFSNSQAIDQVTQLIFHLIQTGLPPIIFGVWDKDFSDEILLANPQIYLTGINSKMYRPRDFWRTILDSLWQSLVIFAVPSLCYWNTEISMGEFGIISVSCVVIAMFSHIMIESRHWSVFHWAICIGTLGIGFYLELFILNSLCVVLLDCNTDNPYKVLHYTMSRGKTYLIIALSTAISLFPRLLIKGFLMESRDSVFYEAHRRINKLGIRKWTTNVSETIKHDPHIFDYKNSKFYLGNLEEFKK------------LKCDKCQFRENFIDKQYPFSFAKYRKNQVLPLNL 1264          

Query: 1840 NVNQGKCPYKDDVLFKFYESESPDETALTKTACQIGIKLLQRGPGFVCIWKDYHQKAFELDALCVFPFDSNRKRMSVIMMDPDTGVITLYCKGADNVILPLISKNTSRQMIDKIVENMELYSKNGLRTLLVAKRRLSEKQFLEWNNRFRIVEQNLSASETELLALYQELERDMILLGATGIEDRLQEEVPECLETLRKAGINIWVLTGDKMETAINIAYSGKLFNENQEIFTLTGNNQETVLDNIEKFCRKISKQQLANSDTSKYNNTLYE-------------YGLILEGKTISVILDEDIVTKAFLTLASHCKSVVCCRSTPTEKAAIVSMVKINLQVRTLAIGDGANDVNMIQTAHVGIGIGGKEGMQAVMASDFAITKFKYLRRLLLVHGHRCYDQLARMSLYMFYKDSIIVLVFFWFQVLNGFSGSVMIDQISQILFNLTMTGLPPLILGIWDKDFESRVLERNPQIYKSGIHLKSYRPRDFWRNIVDSIWQSLVIFWLTYLCYQGTELSMAEFGILCNTSLLIVTYAYMLLESRFWSVFHWLSCVGSLLVAWFAEIFLLNSLCVVIVDCNTDNPYKVVNHTMKQPKTYLVVTLVTAIALFPRVIMKSCLLTSRPSIVYEAL 3681
            N    KCP  D  L   YESESPDE AL KTAC  G KLLQRGP FV IW    ++      L V PFDSNRKRMS+I+  P T  I ++CKGAD+ +    SK+ S    +   + M+ Y++ GLR L++ +R +S+  F EW+ R++  EQ L  +E ELL+L  E+E DM+LLG +GIED LQ+ V + +E+LR+AGI +W+LTGDK ETAINIAYS KLF+ENQ +  L+ +++E   D I++F   I          S Y N + E               L ++G T++  + ED +   FL LA  C SVVC R+TP +KA IV +VK NL+++TLAIGDGANDV+MIQ A VGIGIGG EGMQAVMASDFA+TKFKYL+RLLLVHG  CY++LAR +LYMFYKD+I +L+ FWFQ  N FS S+MID ++Q+LFN+TMTGLPP+I GIWDKD  +  L RNP++Y++GI+ KSY+P  FW NI+D+IWQS VI+ + Y+ +  +++ + EFG +     LI    ++ +E+RFW+ FH L    S ++AW     +   +C  +V C +D+PY  +   M++   +L+  +    A+FPR+ + +   +  P+++Y+ L
Sbjct:  686 NDQDNKCPISDKDLLASYESESPDEMALVKTACIHGYKLLQRGPNFVTIWNPESERPMTYTVLQVLPFDSNRKRMSIIVKCPQTDNIIMFCKGADSAMFGNFSKDISEIDQENTKDYMDAYARMGLRILVMGQRVISKDYFSEWHKRYKEAEQKLGNNEKELLSLTSEIESDMMLLGVSGIEDCLQDGVADTIESLRRAGITVWILTGDKRETAINIAYSAKLFSENQRLIELSASSKEKTHDLIKEFLGNIK---------SNYPNEIMEIRQGKTRPLIRKDLALSVDGSTLTFAM-EDEIKMDFLHLAEQCCSVVCARTTPIQKAEIVQLVKENLRMQTLAIGDGANDVSMIQMADVGIGIGGNEGMQAVMASDFAMTKFKYLKRLLLVHGSWCYNKLARTALYMFYKDTIYILLMFWFQFCNAFSASMMIDPLTQVLFNITMTGLPPIIYGIWDKDLHADTLMRNPELYRNGINCKSYKPWHFWVNILDAIWQSSVIYVICYITFMSSDIGIWEFGQIITACALITCLVHLGIETRFWTWFHGLGIFISFILAWLVFTMIYTVICGKVV-CGSDDPYDFIFQNMQRWLFWLLCVVTPLAAIFPRLTINTIRNSLYPNLLYKGL 1301          

Query:   91 KESQVEESRTIYPSVYHDVDVLSNF-ILKQSSNKLKTTKYNILTFIPLNLFEQFKRFANIYFIAVVCLNFFPEISSFGKETAPLPILFVLFLTAVKDGVEDLRRWQSDRRVNHMPCLLYNNDSQNYEVSYWQDICPGDFVKISANEAIPADILIFRSSELSGNCYIETANLDGEINLKQRQIIHDPEKREYRITPMSFTESHIIVESPNREIYKFNGKWVFEDNAKSITLKKSNLILRGCILRNTQFVEGIVIYAGNETKSLLNNNQLTFKRSKLEQQINRDVXXXXXXXXXXXXXXXXXHVIWMKDXXXXXXXXXXX---XXXXXLKNISLQGFILFWTCLILFQTIIPLPLYVTIELVKLHQLFHITRDLELYDDKVDKRCQVRATNITEDLGQIQYIFCDKTGTLTENLMEFKRATIGFIDFY--DDATES----------------ALTSDSQPISVLAKMLKKCHRNIEI--DENLDISIIEEFVLALAVCNTTMVSENKNESKIVVE 1557
            K++  E+ R IYPS   +    SNF   K ++N+++T KYN +TFIP+NLFEQF RFANIYF+ ++ LNF PEI +FGKE AP+P++FVL +TA+KD VED RR+++D+RVNH  CL+Y+   + +    W     GDF+K+ ANE IPADI++  S+++SG C+IET+NLDGE NLKQR+++       ++  P   + S I VE+PN+EIYKFNG   F+  +  ITL+K+NL+LRGC LRNT+ V GIV+YAG ETK++LNNN   FKRSKLE+QIN+DVIWC+ +LIILC++CSIG+VIW         + ++         ++N ++Q F+ FWT +I +Q +IPLPLYVT E VK+HQ+FHI +DLE+YD++ +K  +VRA NI EDLGQIQY+FCDKTGTLTEN MEFKRA I   D+   DD T+                    +D     +L  ++   H +IEI  +E   +  +++F L + +CNTT+VS NKNE   V++
Sbjct:    7 KKNGEEQCRKIYPSTSTN----SNFEKYKYANNEVRTQKYNAITFIPINLFEQFHRFANIYFVFILILNFLPEIEAFGKEVAPIPVVFVLSVTAIKDAVEDYRRFKADQRVNHSKCLIYSPAKKQFVEQKWSSARCGDFIKLHANETIPADIVLLHSNDISGICHIETSNLDGESNLKQREVVMMENNNTFK--PEMLSNSFIEVENPNQEIYKFNGTIFFKSQSIGITLRKNNLLLRGCTLRNTEEVIGIVVYAGKETKAMLNNNDTRFKRSKLERQINKDVIWCVLLLIILCLSCSIGNVIWTVTSFTQDFIEYYKFPDSIPTVIRNPAMQAFLAFWTSVIYYQALIPLPLYVTFEFVKMHQVFHIRKDLEMYDNEAEKGLEVRAFNIPEDLGQIQYVFCDKTGTLTENRMEFKRAFIDGDDYAVKDDETDGQSDKVTMRSEFGDTDDKKMNDDHGKKLLKNLIPMLHGDIEIKEEEMSRMKNVKDFFLLMGICNTTVVSLNKNEKHPVIK 513