Ig-like domain-containing protein

Overview
NameIg-like domain-containing protein
Smed IDSMED30026372
Length (bp)1393
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ig-like domain-containing protein (SMED30026372) t-SNE clustered cells

Violin plots show distribution of expression levels for Ig-like domain-containing protein (SMED30026372) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ig-like domain-containing protein (SMED30026372) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ig-like domain-containing protein (SMED30026372) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30026372

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30026372h1SMcG0001958 dd_Smed_v4_4231_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30026372h1SMcG0001958 dd_Smed_v4_4231_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30026372h1SMcG0001958 dd_Smed_v4_4231_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A068Y986 (Immunoglobulin OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000737500 PE=4 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 1.717e-28
Identity = 83/271 (30.63%), Postives = 133/271 (49.08%), Query Frame = 3 
Query:  156 IGESVKIKCIVQN----VKDLSVLFRHKEKNIAENGHSYNKEFIVKQYPDKQSTI------YTLEIKELRWAHNGEWDCVQGLSTRKLMISIIVPGTVEPIK-PELELPATDKRRS--------------QMELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSK-RIINATXXXXXXXXXXXAEDGYFTESVIL--IGCREFQMVGSNEVTCKINDYND---SQSVYVLCPGGHRPWTLTNGEIIGLSI 875
            IG+SV ++C V +      +LS++F       AEN  +YN E        + STI      Y   IK + W   G+W C+   S+  + + + VP  + PI    + LP++    S               ++L++H PQI  G G +TNP+DL     + L C+T C  P++   W  NN++ S+ R +  +   ++      AE    + S++   + C  F + G N++ C I D ND   S+ +Y+LCPGG  P TLT+GE+IGL +
Sbjct:   35 IGQSVALRCTVSSRFAHQTNLSIIFLQNGTMKAENCKAYNTERYEVTCEAEGSTINSSTQTYLFHIKSVSWMDRGKWTCLLSGSSSDIFLEVHVPPKMLPIHVSRITLPSSGGLSSTRNSDPQTNNAGGVSVDLASHPPQIY-GLGTRTNPYDLRSGVELHLICQTDCGYPRALPEWTVNNMSESQPRKLEPSRNVITQACDGKAETRNMSTSMVTLKVHCETFHLTGINKLRCAIGDSNDVAASKHIYILCPGGEIPMTLTSGEMIGLGV 304
[Close]
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: U6JJL2 (Immunoglobulin OS=Echinococcus granulosus OX=6210 GN=EGR_06328 PE=4 SV=1)

HSP 1 Score: 122.479 bits (306), Expect = 2.180e-27
Identity = 82/271 (30.26%), Postives = 132/271 (48.71%), Query Frame = 3 
Query:  156 IGESVKIKCIVQN----VKDLSVLFRHKEKNIAENGHSYNKEFIVKQYPDKQSTI------YTLEIKELRWAHNGEWDCVQGLSTRKLMISIIVPGTVEPIK-PELELPATDKRRSQ--------------MELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSK-RIINATXXXXXXXXXXXAEDGYFTESVIL--IGCREFQMVGSNEVTCKINDYND---SQSVYVLCPGGHRPWTLTNGEIIGLSI 875
            IG+SV ++C V +      +LS++F       AEN  +YN E        + STI      Y   IK + W   G+W C+   S+  + + + VP  + PI+   + LP++    S               ++L++H PQI  G G +TNP+DL     + L C+T C  P++   W  NN++ S+ R +      ++       E    + S++   + C  F + G N++ C I D ND   S+ +Y+LCPGG  P TLT+GE+IGL +
Sbjct:   35 IGQSVTLRCTVSSRFAHQTNLSIIFLQNGTMKAENCKAYNTERYEVTCEAEGSTINSSTQTYLFHIKSVSWMDRGKWTCLLSGSSSDIFLEVHVPPKMLPIQVSRITLPSSGGLSSTRSSDPQTNNAGGVGVDLASHPPQIY-GLGTRTNPYDLRSGVELHLICQTDCGYPRALPEWTVNNMSESQPRKLEPRRNVITQACDGKIETRNMSTSMVTLKVHCETFHLTGINKLRCAIGDSNDVAASKHIYILCPGGEIPMTLTSGEMIGLGV 304
[Close]
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A5K4EID0 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 4.646e-27
Identity = 81/279 (29.03%), Postives = 135/279 (48.39%), Query Frame = 3 
Query:  156 IGESVKIKCIVQNVK---DLSVLFRHKEKNIAENGHSYN--KEFIVKQYPDKQ-STIYTLEIKELRWAHNGEWDCVQGLSTRKLMISIIVPGTVEP--IKPELELPATDKRR-----------------------SQMELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSKRIINATXXXXXXXXXXXAE---DGYFTESVILIGCREFQMVGSNEVTCKIN--DYND---SQSVYVLCPGGHRPWTLTNGEIIGLSI 875
            IG+ V ++C +Q ++     +VLFRHKE  I+E    Y   K  ++ +  D Q +  Y L IK + WA  G+W C+   +  K  + +  P  +E   +     LP T+K                         S + +    P   +G G +TNP+DL     I+L C T C +P+++ +W+  N TM+K I+      +     S +    D   TES + + C +  ++G N+V C +N   Y D   +++VY+LC GG RP  LT+GE++G+++
Sbjct:   33 IGQKVILRCQIQGIRLSTKYAVLFRHKETVISEKCFVYQAQKFHLICEPNDWQIAETYELHIKSVSWADRGDWSCIYAANKTKQTLEVYAPAKLEKMGVSSLTSLPVTNKESMIKDSSSPSELSSSSSLATAGLDSALSIIGTPPSQYIGLGTRTNPYDLRSGLGIQLTCATTCGHPRANITWLVMNETMTKAIMPTNPNIIHENVCSNSPNTIDMTTTESNLHVHCSQLDIIGLNQVQCSVNGPQYKDTLLTRNVYILCAGGERPMHLTSGEVVGIAV 311
[Close]
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A4Z2DIS9 (Uncharacterized protein OS=Schistosoma japonicum OX=6182 GN=EWB00_000503 PE=4 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 9.157e-27
Identity = 82/278 (29.50%), Postives = 137/278 (49.28%), Query Frame = 3 
Query:  156 IGESVKIKCIVQNVK---DLSVLFRHKEKNIAENGHSY--NKEFIVKQYPD-KQSTIYTLEIKELRWAHNGEWDCVQGLSTRKLMISIIVPGTVEPIK-PELELPATDKRR-----------------------SQMELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSKRI---INATXXXXXXXXXXXAEDGYFTESVILIGCREFQMVGSNEVTCKIN--DYND---SQSVYVLCPGGHRPWTLTNGEIIGLSI 875
            IG+ V +KC VQ ++     +VLF+ K+K I+E  H Y   K  +V +  D +++  Y L IK + WA  G+W C+   +  +  + +  P  +E +    L LP T+K                         S + +    P   +G G +TNP+DL     I+  C+T C +P+++ +W+  N TM+K I   I+         +     +   T S + I C +  ++G N+V C +N   Y D   +++VYVLCPGG RP  LT+GE++G+++
Sbjct:   38 IGQKVILKCQVQGIRFPMQYAVLFKRKDKLISEKCHVYEGQKYHLVCEPNDWQRAETYELHIKSVSWADRGDWLCIYAANMTRQTLEVYAPAKLEKMGVSSLTLPMTNKESILKESGSFPGLSSTSSLAAAGMDSALSIIGTPPSQHIGLGTRTNPYDLRPGLGIQFTCETTCGHPRANITWLVINETMTKAIMPTISNKINYDYCNNSLNTINMTKTTSTLQIHCTQLDIIGLNQVQCSVNGPQYKDILLTRNVYVLCPGGERPVYLTSGEVVGIAV 315
[Close]
BLAST of Ig-like domain-containing protein vs. TrEMBL
Match: A0A0R3W900 (Ig-like domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS6885 PE=4 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 7.126e-26
Identity = 80/289 (27.68%), Postives = 136/289 (47.06%), Query Frame = 3 
Query:  111 TDLIINHPKEGSTYRIGESVKIKCIVQN----VKDLSVLFRHKEKNIAENGHSYNKEFIVKQYPDKQSTI------YTLEIKELRWAHNGEWDCVQGLSTRKLMISIIVPGTVEPIK-PELELPATDKRRSQ-----------------MELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSK-RIINATXXXXXXXXXXXAEDGYFTESVIL--IGCREFQMVGSNEVTCKINDYND---SQSVYVLCPGGHRPWTLTNGEIIGLSI 875
            +++ +      S   IG+SV ++C V +      +LS++F       AEN  +YN E          +TI      Y   IK + W   G+W C+   S+  + + + VP  + PI+   + LP++    S                   +L++H P+I  G G +TNP+DL     + L C+T C  P++   W  NN++ S+ R ++     ++       E    + S++   + C  F + G N++ C I D N+   S+ +Y+LCPGG  P TLT+GE+IGL +
Sbjct:   20 SEIALTSDSSDSPVLIGQSVTLRCTVSSRFAHQTNLSIIFLQNGTMKAENCKAYNTERYEVTCEAGGNTINSSTQTYLFHIKSISWTDRGKWTCLLSGSSSDIFLEVHVPPKMAPIQVSRIALPSSGGLSSARGTDPHTNNVGGGGSGGADLASHPPRIY-GLGTRTNPYDLRSGVELHLICRTDCGYPRALPEWTVNNMSESQPRKLDPKRNVVTQTCDGKIETRNMSTSMVTLKVHCEAFHLTGINKLRCAIADSNEPAASKHIYILCPGGEIPMTLTSGEMIGLGV 307
[Close]
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000003800.1 (SMESG000003800.1)

HSP 1 Score: 557.37 bits (1435), Expect = 0.000e+0
Identity = 296/297 (99.66%), Postives = 297/297 (100.00%), Query Frame = 3 
Query:   87 WKIVNAQVTDLIINHPKEGSTYRIGESVKIKCIVQNVKDLSVLFRHKEKNIAENGHSYNKEFIVKQYPDKQSTIYTLEIKELRWAHNGEWDCVQGLSTRKLMISIIVPGTVEPIKPELELPATDKRRSQMELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSKRIINATXXXXXXXXXXXAEDGYFTESVILIGCREFQMVGSNEVTCKINDYNDSQSVYVLCPGGHRPWTLTNGEIIGLSIXXXXXXXXXXXXXXSAKKIINSYRYGSVVGGIRV 977
            WKIVNAQVTDLIINHPKEGSTYRIGESVKIKCIVQNVKDLSVLFRHKEKNIAENGHSYNKEFIVKQYPDKQSTIYTLEIKELRWAHNGEWDCVQGLSTRKL+ISIIVPGTVEPIKPELELPATDKRRSQMELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSKRIINATSVSLSSCSLSLAEDGYFTESVILIGCREFQMVGSNEVTCKINDYNDSQSVYVLCPGGHRPWTLTNGEIIGLSIAFALAALMLVLFFMSAKKIINSYRYGSVVGGIRV
Sbjct:   13 WKIVNAQVTDLIINHPKEGSTYRIGESVKIKCIVQNVKDLSVLFRHKEKNIAENGHSYNKEFIVKQYPDKQSTIYTLEIKELRWAHNGEWDCVQGLSTRKLVISIIVPGTVEPIKPELELPATDKRRSQMELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSKRIINATSVSLSSCSLSLAEDGYFTESVILIGCREFQMVGSNEVTCKINDYNDSQSVYVLCPGGHRPWTLTNGEIIGLSIAFALAALMLVLFFMSAKKIINSYRYGSVVGGIRV 309
[Close]
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000078594.1 (SMESG000078594.1)

HSP 1 Score: 118.627 bits (296), Expect = 1.041e-29
Identity = 79/254 (31.10%), Postives = 123/254 (48.43%), Query Frame = 3 
Query:  150 YRIGESVKIKCIVQNVKDLSVLFRHKEKNIAENG------HSYNKEFIVKQYPDKQSTIYTLEIKELRWAHNGEWDCVQGLSTRKLMISIIVPGT-----VEPIKPELELPATDKRRSQMELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSKRIINATXXXXXXXXXXXAEDG-YFTESVILIGCREFQMVGSNEVTCKINDYNDSQSVYVLCPGGHRPWTLTNGEIIGLSI 875
            Y    +V + C +Q +    V    K+KN+   G        Y      K    K+   Y  +IK++ W  +GEW C      + + I I VP +     +EPIKPE  + + +       + +    I+ G+G +TNP++L     +K+ C + CS P+  HSW Y N++     I   +    +  +    +G Y  ES  +I C   +MVG+NE+ C+  +   S +VYVLCPGG R W LT GEIIGL++
Sbjct:   38 YEQNTTVILSCEIQELLSTFVTMFRKDKNMRSEGCRVFDTQKYEMVCSDKVIDGKKFIKYEFKIKKVEWLDHGEWYCFYSNYRKSVTIDIKVPASFEALNIEPIKPE-GIKSNNLGPDFSPIDSKGNIIVRGRGSRTNPYNLRTGIALKIKCYSSCSYPRIVHSWSYANMSHGPIDIEVKNQRERNICILPKTEGMYSIESEAVINCTALKMVGANEIVCRSAESKKS-NVYVLCPGGERAWELTTGEIIGLAV 289
[Close]
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000056440.1 (SMESG000056440.1)

HSP 1 Score: 103.219 bits (256), Expect = 3.434e-24
Identity = 71/254 (27.95%), Postives = 129/254 (50.79%), Query Frame = 3 
Query:  153 RIGESVKIKCIVQNVKDLSVLFRHKEKNIAENGHSYNKEFIVKQY--PDKQSTIYTLEIKELRWAHNGEWDCVQGLSTRKLMISIIVPG----TVEPIKPELELPATDKRRSQMELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSKRIINATXXXXXXXXXXXAEDGYFTESVILIGCREFQMVGSNEVTC-----KINDYNDSQ-SVYVLCPGGH-RPWTLTNGEIIGLSI 875
            ++  ++ + CI+QN+    +LF  K+  ++E    YNK     QY    K  T Y  EIK++ W   G+W C+ GL +  +M+ I VP     ++EPI  ++   +++     +  S+    IL G+G K NP+DL ++  + L CK+ CS P  +  +++ N +   + ++    +    +  + ++   T S +   C+ F++ G   +TC     K +  N SQ ++Y+LCP    + W +TNGE+I   I
Sbjct:   35 KLNGNIVLTCIIQNISKSPLLFSRKDDLVSEKCKVYNKS----QYGITCKNGTEYKFEIKKMSWIDKGKWKCMVGLYSTSIMLDIYVPSNVSISIEPISKKVF--SSNLGPESIPSSHENSIILKGRGQKLNPYDLRKNISVNLICKSDCSYPVVNQVYIFKNFSNFSKELSKKPDNTEINTCDIEQNKTSTISRLKFNCQAFKLTGLINLTCSTFIDKHSILNISQRTIYILCPTEPIQWWKMTNGEMINTVI 282
[Close]
BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Match: SMESG000056440.1 (SMESG000056440.1)

HSP 1 Score: 76.6406 bits (187), Expect = 1.191e-15
Identity = 52/193 (26.94%), Postives = 98/193 (50.78%), Query Frame = 3 
Query:  330 LRWAHNGEWDCVQGLSTRKLMISIIVPG----TVEPIKPELELPATDKRRSQMELSNHLPQILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSKRIINATXXXXXXXXXXXAEDGYFTESVILIGCREFQMVGSNEVTC-----KINDYNDSQ-SVYVLCPGGH-RPWTLTNGEIIGLSI 875
            + W   G+W C+ GL +  +M+ I VP     ++EPI  ++   +++     +  S+    IL G+G K NP+DL ++  + L CK+ CS P  +  +++ N +   + ++    +    +  + ++   T S +   C+ F++ G   +TC     K +  N SQ ++Y+LCP    + W +TNGE+I   I
Sbjct:    1 MSWIDKGKWKCMVGLYSTSIMLDIYVPSNVSISIEPISKKVF--SSNLGPESIPSSHENSIILKGRGQKLNPYDLRKNISVNLICKSDCSYPVVNQVYIFKNFSNFSKELSKKPDNTEINTCDIEQNKTSTISRLKFNCQAFKLTGLINLTCSTFIDKHSILNISQRTIYILCPTEPIQWWKMTNGEMINTVI 191
The following BLAST results are available for this feature:
BLAST of Ig-like domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A068Y9861.717e-2830.63Immunoglobulin OS=Echinococcus multilocularis OX=6... [more]
U6JJL22.180e-2730.26Immunoglobulin OS=Echinococcus granulosus OX=6210 ... [more]
A0A5K4EID04.646e-2729.03Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A4Z2DIS99.157e-2729.50Uncharacterized protein OS=Schistosoma japonicum O... [more]
A0A0R3W9007.126e-2627.68Ig-like domain-containing protein OS=Taenia asiati... [more]
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BLAST of Ig-like domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Ig-like domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000003800.10.000e+099.66SMESG000003800.1[more]
SMESG000078594.11.041e-2931.10SMESG000078594.1[more]
SMESG000056440.13.434e-2427.95SMESG000056440.1[more]
SMESG000056440.11.191e-1526.94SMESG000056440.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026372 ID=SMED30026372|Name=Ig-like domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1393bp
AGTAGTTTATTTCAATTTCAAATACTGGATTTCAAAGTTTTGATTTTTTA
ATGATTCATAAACTATTTCTGTTAATATTTTTCTTCTGGAAAATTGTCAA
TGCTCAGGTTACTGATTTAATAATCAATCATCCAAAAGAAGGTAGTACGT
ACAGGATAGGTGAAAGTGTTAAGATTAAATGCATAGTTCAAAATGTAAAG
GATCTGTCTGTGTTATTTCGTCACAAAGAAAAAAATATTGCTGAAAATGG
GCACAGTTATAACAAAGAATTTATTGTCAAACAATATCCAGATAAACAGT
CTACGATATATACTTTAGAAATTAAAGAATTACGTTGGGCACATAATGGT
GAATGGGATTGTGTACAGGGACTTTCGACGAGAAAACTAATGATATCAAT
TATAGTTCCTGGAACTGTTGAACCGATTAAGCCTGAGCTCGAATTGCCTG
CAACTGACAAACGTCGTTCGCAGATGGAACTGAGCAATCATTTGCCTCAG
ATTCTTCTAGGCAAAGGCATCAAAACCAATCCGTTTGATTTGACCCGGGA
CGCCCGAATAAAGCTGTATTGCAAGACCGGGTGCAGCAATCCACAGAGTC
ACCACAGTTGGATGTACAACAATATTACGATGTCGAAACGCATTATTAAT
GCCACTAGCGTATCTCTGTCGAGTTGCAGCCTCTCATTGGCTGAAGACGG
GTATTTCACAGAGTCGGTCATTCTGATTGGCTGCCGAGAATTCCAGATGG
TCGGATCGAATGAGGTCACGTGCAAGATAAATGATTACAATGATTCACAA
TCGGTCTACGTGCTGTGTCCAGGGGGGCACAGACCGTGGACTCTCACCAA
TGGGGAAATCATTGGACTATCCATTGCTTTTGCATTGGCAGCTCTCATGC
TGGTTCTGTTCTTTATGTCCGCTAAGAAGATCATCAACAGTTACCGCTAT
GGATCAGTAGTCGGAGGGATCCGTGTGTGATTTATTGATTTACTGATTGT
GTGTGTGTGTTTCGCGGGAATTTTACCTATGCATTTCATATTTATATATA
TTCCTACTACTCTGAACTGGCAATATTGACATCTCTGCACTACTTATCGG
GTTGCTATTACTATTGATATTGATTTCAGCTTCAGTCCTTGTTTGTGTGC
AATCAGTTCTATTTTTATGTTGTTATTGTTGTCACAGTAAATGCCACAAC
CAATCTGGAGGATCTTCAACCATTTTGTTTCATATTTTGTTGAATTATTT
TATTCGTGATTAAAATTGGAATCAGTGCTTTTTGCAATTAATTTTCTTTT
CTTTTAGGAATTATCAGTATTTAATGTACTTTACTTTAATGTCTATAATA
TTATGCCCATAATCATAATATAAATAAATTGATTATAATAATG
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protein sequence of SMED30026372-orf-1

>SMED30026372-orf-1 ID=SMED30026372-orf-1|Name=SMED30026372-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=310bp
MIHKLFLLIFFFWKIVNAQVTDLIINHPKEGSTYRIGESVKIKCIVQNVK
DLSVLFRHKEKNIAENGHSYNKEFIVKQYPDKQSTIYTLEIKELRWAHNG
EWDCVQGLSTRKLMISIIVPGTVEPIKPELELPATDKRRSQMELSNHLPQ
ILLGKGIKTNPFDLTRDARIKLYCKTGCSNPQSHHSWMYNNITMSKRIIN
ATSVSLSSCSLSLAEDGYFTESVILIGCREFQMVGSNEVTCKINDYNDSQ
SVYVLCPGGHRPWTLTNGEIIGLSIAFALAALMLVLFFMSAKKIINSYRY
GSVVGGIRV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000101muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR036179Ig-like_dom_sf
IPR013783Ig-like_fold
IPR007110Ig-like_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013783Immunoglobulin-like foldGENE3DG3DSA:2.60.40.10coord: 23..112
e-value: 9.4E-6
score: 27.7
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..18
score: 0.926
NoneNo IPR availableTMHMMTMhelixcoord: 270..289
IPR036179Immunoglobulin-like domain superfamilySUPERFAMILYSSF48726Immunoglobulincoord: 29..119