Phospholipase A2

Overview
NamePhospholipase A2
Smed IDSMED30026339
Length (bp)893
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Phospholipase A2 (SMED30026339) t-SNE clustered cells

Violin plots show distribution of expression levels for Phospholipase A2 (SMED30026339) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Phospholipase A2 (SMED30026339) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Phospholipase A2 (SMED30026339) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30026339

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 17

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30026339h1SMcG0017625 dd_Smed_v4_3851_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30026339h1SMcG0017625 dd_Smed_v4_3851_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30026339h1SMcG0017625 dd_Smed_v4_3851_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026339h1SMcG0017625 Contig51228uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026339h1SMcG0017625 Contig51228newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30026339h1SMcG0017625 dd_Smed_v6_3851_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
epidermisSMED30026339h1SMcG0017625 DN297710smed_ncbi_20240424PMID:30399335
Ross et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30026339h1SMcG0017625 Contig51228uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30026339h1SMcG0017625 Contig51228newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30026339h1SMcG0017625 Contig51228uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30026339h1SMcG0017625 Contig51228newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30026339h1SMcG0017625 Contig51228uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
parenchymaSMED30026339h1SMcG0017625 Contig51228newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
pigment cellSMED30026339h1SMcG0017624 dd_Smed_v6_3851_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
pigment cellSMED30026339h1SMcG0017625 dd_Smed_v6_3851_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
reproductive organSMED30026339h1SMcG0017625 Contig51228uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30026339h1SMcG0017625 Contig51228newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Phospholipase A2 vs. Ensembl Human
Match: PLA2G3 (phospholipase A2 group III [Source:HGNC Symbol;Acc:HGNC:17934])

HSP 1 Score: 98.2117 bits (243), Expect = 2.243e-22
Identity = 53/139 (38.13%), Postives = 71/139 (51.08%), Query Frame = 3 
Query:  333 ERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKY 749
            +R   Q+       +R+KR       PGT WCG G+ A N S+ G     D CC EHD+C   I   +  +  +N   HT+  C CD  F  CL+   + +SD VG  FFNVL++ CF  E  + CV+WY  G  CR Y
Sbjct:  131 KRAAGQSGVPGGGHQREKRGW---TMPGTLWCGVGDSAGNSSELGVFQGPDLCCREHDRCPQNISPLQYNYGIRNYRFHTISHCDCDTRFQQCLQNQHDSISDIVGVAFFNVLEIPCFVLEEQEACVAWYWWGG-CRMY 265
[Close]
BLAST of Phospholipase A2 vs. Ensembl Fly
Match: CG3009 (gene:FBgn0029720 transcript:FBtr0332316)

HSP 1 Score: 97.8265 bits (242), Expect = 6.191e-24
Identity = 42/101 (41.58%), Postives = 56/101 (55.45%), Query Frame = 3 
Query:  387 RSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQ 689
            R  L  IYPGTKWCGPG  A +  D G     D+CC EHD C   +  GE +    N+ + T   C CD  F  CL+  +   ++ +G +F+NV+QV CFQ
Sbjct:   97 RGGLGFIYPGTKWCGPGTAATSYDDLGAHAREDRCCREHDMCPDVLNVGECRRGLCNRGTFTRSHCDCDARFRRCLQAANTETANTLGAIFYNVVQVTCFQ 197
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BLAST of Phospholipase A2 vs. Ensembl Fly
Match: CG42237 (gene:FBgn0250862 transcript:FBtr0340302)

HSP 1 Score: 97.0561 bits (240), Expect = 4.761e-23
Identity = 44/103 (42.72%), Postives = 61/103 (59.22%), Query Frame = 3 
Query:  378 RKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCF 686
            R   S+L  I PGTKWCG G+IAE  SD G E+  D+CC +HD C + I A + K+   N   +T   C CDD  + CLK  +   S  +G+++FN++QV C 
Sbjct:  191 RSPFSLLSGIIPGTKWCGTGDIAETYSDLGSEMAMDRCCRQHDLCPIKIRAYQNKYELMNDSLYTKSHCICDDMLFSCLKMTNTSASQLMGSIYFNLVQVPCL 293
[Close]
BLAST of Phospholipase A2 vs. Ensembl Fly
Match: CG3009 (gene:FBgn0029720 transcript:FBtr0070688)

HSP 1 Score: 97.4413 bits (241), Expect = 5.175e-23
Identity = 42/101 (41.58%), Postives = 56/101 (55.45%), Query Frame = 3 
Query:  387 RSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQ 689
            R  L  IYPGTKWCGPG  A +  D G     D+CC EHD C   +  GE +    N+ + T   C CD  F  CL+  +   ++ +G +F+NV+QV CFQ
Sbjct:   97 RGGLGFIYPGTKWCGPGTAATSYDDLGAHAREDRCCREHDMCPDVLNVGECRRGLCNRGTFTRSHCDCDARFRRCLQAANTETANTLGAIFYNVVQVTCFQ 197
[Close]
BLAST of Phospholipase A2 vs. Ensembl Fly
Match: CG3009 (gene:FBgn0029720 transcript:FBtr0300468)

HSP 1 Score: 97.4413 bits (241), Expect = 5.175e-23
Identity = 42/101 (41.58%), Postives = 56/101 (55.45%), Query Frame = 3 
Query:  387 RSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQ 689
            R  L  IYPGTKWCGPG  A +  D G     D+CC EHD C   +  GE +    N+ + T   C CD  F  CL+  +   ++ +G +F+NV+QV CFQ
Sbjct:   97 RGGLGFIYPGTKWCGPGTAATSYDDLGAHAREDRCCREHDMCPDVLNVGECRRGLCNRGTFTRSHCDCDARFRRCLQAANTETANTLGAIFYNVVQVTCFQ 197
[Close]
BLAST of Phospholipase A2 vs. Ensembl Fly
Match: CG42237 (gene:FBgn0250862 transcript:FBtr0073722)

HSP 1 Score: 96.6709 bits (239), Expect = 1.204e-22
Identity = 44/103 (42.72%), Postives = 61/103 (59.22%), Query Frame = 3 
Query:  378 RKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCF 686
            R   S+L  I PGTKWCG G+IAE  SD G E+  D+CC +HD C + I A + K+   N   +T   C CDD  + CLK  +   S  +G+++FN++QV C 
Sbjct:  245 RSPFSLLSGIIPGTKWCGTGDIAETYSDLGSEMAMDRCCRQHDLCPIKIRAYQNKYELMNDSLYTKSHCICDDMLFSCLKMTNTSASQLMGSIYFNLVQVPCL 347
[Close]
BLAST of Phospholipase A2 vs. Ensembl Zebrafish
Match: proca1 (protein interacting with cyclin A1 [Source:ZFIN;Acc:ZDB-GENE-110418-1])

HSP 1 Score: 103.605 bits (257), Expect = 3.046e-24
Identity = 54/135 (40.00%), Postives = 75/135 (55.56%), Query Frame = 3 
Query:  351 TDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQR 755
            T  + E S +K R+     YPGT WCG GNIA++    GE  ETD+CC  HD C   I A    + + N   H+L  C CD+    CL+ V++  S  VG  FFNV++V CF+    + CV  +  G+ C+KY+R
Sbjct:  135 TKQVKEASNKKTRTKRGFTYPGTLWCGAGNIADHYEQLGEFEETDRCCRVHDHCPYVIHAFSSNYGYTNFKWHSLSHCDCDNALKECLRLVNDTSSRVVGQAFFNVIEVPCFEFSFEEQCVERHWYGV-CKKYER 268
[Close]
BLAST of Phospholipase A2 vs. Ensembl Zebrafish
Match: pla2g3 (phospholipase A2 group III [Source:ZFIN;Acc:ZDB-GENE-051113-96])

HSP 1 Score: 87.0409 bits (214), Expect = 8.497e-19
Identity = 49/127 (38.58%), Postives = 66/127 (51.97%), Query Frame = 3 
Query:  309 GQKLNTITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQ 689
             + L ++      + D+   + K  +RS    + PGT WCG GN A   +D G   ETDKCC EHD CK  I +        N    TL  C CD+ F  CL  V+N +S+ VG  FFNVL++ CF+
Sbjct:  127 ARDLMSVEPDGFVEQDSDVSSIKTLQRSKRAWMIPGTLWCGSGNKATGWTDLGVFEETDKCCREHDHCKHTIPSFSYDHGVFNTNLFTLSHCDCDNRFRRCLLGVNNSMSNLVGYGFFNVLKMSCFE 253
[Close]
BLAST of Phospholipase A2 vs. Ensembl Zebrafish
Match: CU459012.1 (group 3 secretory phospholipase A2-like [Source:NCBI gene;Acc:101885160])

HSP 1 Score: 80.8777 bits (198), Expect = 1.134e-16
Identity = 45/137 (32.85%), Postives = 68/137 (49.64%), Query Frame = 3 
Query:  324 TITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGI 734
            T+ E   KQ   +   S+ K RS    + PGT WCG G  A +    G     D+CC EHD C+  I +  + +   N    T+  C CD  F  CL   ++ +S+ VG  FFNVL+++CF+    + C  +  +G+
Sbjct:  129 TLREENAKQNQQM--DSRVKIRSKRAWVLPGTLWCGRGTNANDYEQLGMFEHADRCCREHDHCEHIIRSFSVNFGVFNPTFFTVSHCDCDHRFKQCLLGGNDTISNMVGYSFFNVLKIRCFEFIQRRQCTQYNWLGL 263
[Close]
BLAST of Phospholipase A2 vs. Ensembl Xenopus
Match: uri1 (URI1 prefoldin-like chaperone [Source:Xenbase;Acc:XB-GENE-960711])

HSP 1 Score: 103.99 bits (258), Expect = 1.406e-24
Identity = 53/137 (38.69%), Postives = 69/137 (50.36%), Query Frame = 3 
Query:  348 QTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQRQ 758
            QT       +R KR      YPGT WCG GN AE   D GE   TD CC  HD C   I     ++ ++N   HT+  C CD +F  CL+ V++  S  VG  F+NV++V CF+      CV  Y  G WC+ Y  +
Sbjct:  111 QTTPAEPELRRVKRGF---TYPGTLWCGAGNNAETFEDLGEHTATDACCRTHDHCAHVIHPFSYRYGYRNYLWHTISHCQCDTQFKDCLRRVNDTASRVVGQAFYNVIKVPCFEFMYKSQCVERYWYG-WCKTYNNE 243
[Close]
BLAST of Phospholipase A2 vs. Ensembl Xenopus
Match: ENSXETT00000036327.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:1:131649089:131653788:-1 gene:ENSXETG00000016424.1 transcript:ENSXETT00000036327.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.3445 bits (207), Expect = 4.686e-20
Identity = 41/107 (38.32%), Postives = 61/107 (57.01%), Query Frame = 3 
Query:  411 PGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIG 731
            PGT WCG G+ A+N ++ GE+I       EHD C   I A + ++  +N   HT+  C CD  F LCL   ++ +S  VG +FFN+L++ CF  +  + CV W+  G
Sbjct:    2 PGTLWCGAGSSADNFTNLGEKIHPQ----EHDHCSHQIEAFQFQYGMRNYRLHTVSHCDCDQRFRLCLNAFNDTISTLVGIMFFNILEMPCFSLKEEEQCVEWFWWG 104
[Close]
BLAST of Phospholipase A2 vs. Ensembl Mouse
Match: Pla2g3 (phospholipase A2, group III [Source:MGI Symbol;Acc:MGI:2444945])

HSP 1 Score: 95.5153 bits (236), Expect = 9.789e-22
Identity = 53/141 (37.59%), Postives = 70/141 (49.65%), Query Frame = 3 
Query:  369 TSKRKKRSILQK--------------IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKY 749
            T  R+KR+I Q                 PGT WCG GN AEN S+ G     D CC EHD+C   I   +  +  +N   HT+  C CD  F  CL+   + +SD +G  FFNVL++ CF  +  + CV+W   G  CR Y
Sbjct:  122 TGAREKRAIEQSGAPDREHRRRRRGWTIPGTLWCGVGNSAENASELGVFHGPDLCCREHDQCPQTISPLQYNYGIRNFRFHTISHCDCDARFQQCLRSQGDSISDIMGVAFFNVLEIPCFVLKEQEACVAWNWWG-GCRAY 261
[Close]
BLAST of Phospholipase A2 vs. Ensembl Mouse
Match: Pla2g3 (phospholipase A2, group III [Source:MGI Symbol;Acc:MGI:2444945])

HSP 1 Score: 95.5153 bits (236), Expect = 1.366e-21
Identity = 53/141 (37.59%), Postives = 70/141 (49.65%), Query Frame = 3 
Query:  369 TSKRKKRSILQK--------------IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKY 749
            T  R+KR+I Q                 PGT WCG GN AEN S+ G     D CC EHD+C   I   +  +  +N   HT+  C CD  F  CL+   + +SD +G  FFNVL++ CF  +  + CV+W   G  CR Y
Sbjct:  122 TGAREKRAIEQSGAPDREHRRRRRGWTIPGTLWCGVGNSAENASELGVFHGPDLCCREHDQCPQTISPLQYNYGIRNFRFHTISHCDCDARFQQCLRSQGDSISDIMGVAFFNVLEIPCFVLKEQEACVAWNWWGG-CRAY 261
[Close]
BLAST of Phospholipase A2 vs. UniProt/SwissProt
Match: sp|P16354|PA23_HELSU (Phospholipase A2 isozymes PA3A/PA3B/PA5 OS=Heloderma suspectum OX=8554 PE=1 SV=3)

HSP 1 Score: 100.138 bits (248), Expect = 7.973e-25
Identity = 45/105 (42.86%), Postives = 64/105 (60.95%), Query Frame = 3 
Query:  405 IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSW 719
            I PGT WCG GN A + S  G E +TD CC +HD C+ +I A E K   +N +  T+  C CD++F  CL ++ +  +D VG  +FNVL++ CF+ E  + CV W
Sbjct:    4 IMPGTLWCGAGNAASDYSQLGTEKDTDMCCRDHDHCENWISALEYKHGMRNYYPSTISHCDCDNQFRSCLMKLKDGTADYVGQTYFNVLKIPCFELEEGEGCVDW 108
[Close]
BLAST of Phospholipase A2 vs. UniProt/SwissProt
Match: sp|Q7M4I5|PA2_APIDO (Phospholipase A2 OS=Apis dorsata OX=7462 PE=1 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 4.359e-24
Identity = 45/98 (45.92%), Postives = 59/98 (60.20%), Query Frame = 3 
Query:  405 IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDK-VGNLFFNVLQVKCFQRE 695
            IYPGT WCG GN++ +  + G    TD CC  HD C   + AGE K    N  SHT +SC CDD+FY CLK   + +S   VG ++FN+L  KC++ E
Sbjct:    2 IYPGTLWCGHGNVSSSPDELGRFKHTDSCCRSHDMCPDVMSAGESKHGLTNTASHTRLSCDCDDKFYDCLKNSSDTISSYFVGEMYFNILDTKCYKLE 99
[Close]
BLAST of Phospholipase A2 vs. UniProt/SwissProt
Match: sp|P80003|PA2A2_HELSU (Acidic phospholipase A2 PA4 OS=Heloderma suspectum OX=8554 PE=1 SV=2)

HSP 1 Score: 96.6709 bits (239), Expect = 1.633e-23
Identity = 45/103 (43.69%), Postives = 60/103 (58.25%), Query Frame = 3 
Query:  405 IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCV 713
            I PGT WCG GN A + S  G E +TD CC +HD C   + A E K   +N   HT+  C CD++F  CL  V +R +D VG  +F VL++ CF+ E  + CV
Sbjct:    4 IMPGTLWCGAGNAASDYSQLGTEKDTDMCCRDHDHCSDTMAALEYKHGMRNYRPHTVSHCDCDNQFRSCLMNVKDRTADLVGMTYFTVLKISCFELEEGEGCV 106
[Close]
BLAST of Phospholipase A2 vs. UniProt/SwissProt
Match: sp|Q9BMK4|PA2_APICC (Phospholipase A2 OS=Apis cerana cerana OX=94128 PE=2 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 2.518e-23
Identity = 44/98 (44.90%), Postives = 59/98 (60.20%), Query Frame = 3 
Query:  405 IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDK-VGNLFFNVLQVKCFQRE 695
            IYPGT WCG GN++   ++ G    TD CC  HD C   + AGE K    N  SHT +SC CDD FY CLK   +++S   VG ++FN++  KC++ E
Sbjct:    2 IYPGTLWCGHGNVSSGPNELGRFKHTDACCRTHDMCPDVMSAGESKHGLTNTASHTRLSCDCDDTFYDCLKNSGDKISSYFVGKMYFNLIDTKCYKLE 99
[Close]
BLAST of Phospholipase A2 vs. UniProt/SwissProt
Match: sp|I7GQA7|PA2_XYLAI (Phospholipase A(2) OS=Xylocopa appendiculata circumvolans OX=135722 GN=PLA2 PE=1 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 8.920e-22
Identity = 49/118 (41.53%), Postives = 63/118 (53.39%), Query Frame = 3 
Query:  405 IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCV--SWYVIGIWCRKYQ 752
            I+ GTKWCG GN+AE   D G   ETD CC EHD C   I AG+ K    N  S+T ++C CD++FY CLK      S  V   +F +L   C++ E    CV   W+     C KY+
Sbjct:   41 IFVGTKWCGNGNVAEGPEDLGSLKETDACCREHDMCPDLIEAGQSKHGLTNTASYTRLNCACDEKFYNCLKNSSETGSGAVRFTYFTLLGTMCYRNEHPLICVKKGWFS----CSKYE 154
[Close]
BLAST of Phospholipase A2 vs. TrEMBL
Match: A0A4Y2KMI8 (Phospholipase A2 OS=Araneus ventricosus OX=182803 GN=PA2_1 PE=3 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 1.650e-29
Identity = 59/146 (40.41%), Postives = 84/146 (57.53%), Query Frame = 3 
Query:  312 QKLNTITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKY 749
            +KL ++    +++  T    + +K    L  IYPGTKWCG GN+A ++ D G E ETDKCC  HDKC+ FI  GE K+   NK S+  +SC CD++FY CL+  +   S+ VG L+FN    KCF  +  K C  + +    C +Y
Sbjct:   79 RKLGSLVTDPVEELKTTASQATQKASGWL--IYPGTKWCGVGNVAASDDDLGPEEETDKCCRTHDKCRDFISGGETKYNLTNKSSYVSLSCECDNKFYECLRRANTISSNSVGFLYFNFFARKCFSLDYPKKCKKYTMFSKICSEY 222
[Close]
BLAST of Phospholipase A2 vs. TrEMBL
Match: A0A0C9S3A5 (TSA: Tityus bahiensis Tbah00274 mRNA sequence (Fragment) OS=Tityus bahiensis OX=50343 PE=2 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 4.578e-28
Identity = 63/176 (35.80%), Postives = 102/176 (57.95%), Query Frame = 3 
Query:  327 ITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQRE--VIKTCVSW--YVIGIWCRKYQRQ---------LGIKLYNSQNWN*FAKDLM 815
            + E   K   T Y+ +++  +S+L  I+PGTKWCG G++A++  D G  IETD CC  HD C   I   + K+  KNK  +T   C CD+EF+ CLK+ +  +SD VG+LFFN+LQ +CF+++  ++K    W   ++   C++Y++             K+Y  ++ + F KDL+
Sbjct:   33 VREGTFKIIKTPYDFARKIFKSVL--IFPGTKWCGAGDVADDYDDLGPAIETDMCCRTHDHCNNSIEGFKTKYDLKNKDFYTKSHCDCDNEFHQCLKDGETLISDAVGHLFFNILQTQCFKKDYPIVKCLKKWGIPIVRDVCQEYEQDENKPQKYQFFDGKMYQGKHESSFLKDLL 206
[Close]
BLAST of Phospholipase A2 vs. TrEMBL
Match: A0A2I9LPG1 (Phospholipase A2 OS=Centruroides hentzi OX=88313 PE=4 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 1.608e-26
Identity = 60/130 (46.15%), Postives = 79/130 (60.77%), Query Frame = 3 
Query:  372 SKRKKRSILQK--IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREV-IKTCVSWYVIGIWCRKYQ 752
            SKR    +L+K  I+PGT WCG GN++ N  D G   ++D CC  HD+C   I A E K+   N    TL  C CDDEFY CLKEV++  S  +GNLFFNVL++KCF+ +  IK C+    I   C +Y+
Sbjct:   86 SKRTINKLLRKLAIFPGTNWCGAGNVSNNARDLGAFEKSDDCCRSHDQCFDVINANETKYGLYNARLVTLSHCDCDDEFYECLKEVNSPASFSIGNLFFNVLKMKCFREDYPIKGCLKETGIIKVCEEYE 215
[Close]
BLAST of Phospholipase A2 vs. TrEMBL
Match: A0A087UYP2 (Phospholipase A2 (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_23721 PE=3 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 2.859e-26
Identity = 53/119 (44.54%), Postives = 77/119 (64.71%), Query Frame = 3 
Query:  405 IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQRE--VIKTCVSWYVIGIWCRKYQR 755
            ++PGTKWCG G+ A++  D G E ETDKCC  HD C   +  GE K    N    TL+SCGCD+EFY CL++V+   S+ +GNL+FN+L  KC++ +  V+K C+ +  +   C +Y+R
Sbjct:  144 VFPGTKWCGAGDKAQSYDDLGSEAETDKCCRAHDLCDDMLRTGEKKGDLINDSQFTLLSCGCDEEFYSCLEKVNTGTSNTIGNLYFNLLDRKCYKLDYPVVK-CLRYKFLSSTCAEYER 261
[Close]
BLAST of Phospholipase A2 vs. TrEMBL
Match: A0A218QXE2 (Putative phospholipase A2 (Fragment) OS=Tityus serrulatus OX=6887 PE=3 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 3.746e-26
Identity = 62/176 (35.23%), Postives = 100/176 (56.82%), Query Frame = 3 
Query:  327 ITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQRE--VIKTCVSW--YVIGIWCRKYQRQ---------LGIKLYNSQNWN*FAKDLM 815
            + E   K   T Y+ +++  +S+L  I+PGTKWCG G++A++  D G  IETD CC  HD C   I   + K   KNK  +T   C CD+EF+ CL + +  +SD VG+LFFN+LQ +CF+++  ++K    W   ++   C++Y++             K+Y  ++ + F KDL+
Sbjct:  111 VREGTFKIIKTPYDFARKIFKSVL--IFPGTKWCGAGDVADDYDDLGPAIETDMCCRTHDHCNSSIEGFKTKHDLKNKDFYTKSHCDCDNEFHQCLIDGETLISDAVGHLFFNILQTQCFKKDYPIVKCLKKWGIPIVRDVCQEYEQDETKPQKYQFFDGKMYQGKHESSFLKDLL 284
[Close]
BLAST of Phospholipase A2 vs. Ensembl Cavefish
Match: proca1 (uncharacterized LOC103023370 [Source:NCBI gene;Acc:103023370])

HSP 1 Score: 102.449 bits (254), Expect = 5.603e-24
Identity = 53/127 (41.73%), Postives = 70/127 (55.12%), Query Frame = 3 
Query:  375 KRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQR 755
            +R KR      YPGT WCG GNIAEN    GE  ETDKCC  HD C   I A    + + N   H+L  C CD+    CL+ V++  S  VG  FFNV++V CF+    + CV  +  G+ C++Y +
Sbjct:  158 RRSKRGF---TYPGTLWCGAGNIAENYDQLGEFAETDKCCRTHDHCPHVIHAFSSNYGYTNFKWHSLSHCDCDNALKKCLRVVNDTSSRVVGQAFFNVIEVPCFEFAFEEQCVERHWYGV-CKRYDQ 280
[Close]
BLAST of Phospholipase A2 vs. Ensembl Cavefish
Match: proca1 (uncharacterized LOC103023370 [Source:NCBI gene;Acc:103023370])

HSP 1 Score: 98.2117 bits (243), Expect = 2.343e-23
Identity = 52/128 (40.62%), Postives = 72/128 (56.25%), Query Frame = 3 
Query:  372 SKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQR 755
            +++ +RS     YPGT WCG GNIAEN    GE  ETDKCC  HD C   I A    + + N   H+L  C CD+    CL+ V++  S  VG  FFNV++V CF+    + CV  +  G+ C++Y +
Sbjct:  144 AQKLRRSKRGFTYPGTLWCGAGNIAENYDQLGEFAETDKCCRTHDHCPHVIHAFSSNYGYTNFKWHSLSHCDCDN----CLRVVNDTSSRVVGQAFFNVIEVPCFEFAFEEQCVERHWYGV-CKRYDQ 266
[Close]
BLAST of Phospholipase A2 vs. Ensembl Cavefish
Match: ENSAMXT00000053537.1 (uncharacterized LOC103036138 [Source:NCBI gene;Acc:103036138])

HSP 1 Score: 75.8702 bits (185), Expect = 4.845e-15
Identity = 43/119 (36.13%), Postives = 63/119 (52.94%), Query Frame = 3 
Query:  378 RKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIK----TCVSWY 722
            R+KR+    I PGT WCG G+ A      G     D+CC EHD C   I    + +   N    T+  C CD  F  CL  V++ VS+ VG  FF++L+++CF  ++IK    T ++W+
Sbjct:  137 RRKRAW---ILPGTLWCGRGSSAGEYEQLGMFELADRCCREHDHCSHIIRPFTVNYGVFNPSFFTISHCDCDYRFKQCLLNVNDSVSNMVGYTFFHILKLRCF--DLIKKRRCTQLNWF 250
[Close]
BLAST of Phospholipase A2 vs. Ensembl Cavefish
Match: ENSAMXT00000057577.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:581752:584954:1 gene:ENSAMXG00000036121.1 transcript:ENSAMXT00000057577.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 53.1434 bits (126), Expect = 1.315e-8
Identity = 27/76 (35.53%), Postives = 42/76 (55.26%), Query Frame = 3 
Query:  489 CCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVS 716
            CC EHD CK  I +    +   N    TL  C CD +F  CL + ++ +++ VG  +FNVL+++CF+      CV+
Sbjct:    2 CCREHDHCKDSITSFGFNYGVLNTNIFTLSHCDCDKKFQQCLHKANDSMANVVGYGYFNVLKMRCFEFAERMECVN 77
[Close]
BLAST of Phospholipase A2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005482.1 (pep scaffold:Pmarinus_7.0:GL479025:28110:33430:-1 gene:ENSPMAG00000004987.1 transcript:ENSPMAT00000005482.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 91.2781 bits (225), Expect = 5.019e-23
Identity = 45/117 (38.46%), Postives = 63/117 (53.85%), Query Frame = 3 
Query:  408 YPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWY----VIGIWCRK 746
            YPGT WCGPG  A +  + G   +TD CC EHD C   IG  E K+ + N   HT+  C CD +F  C+KE ++  +  +G  +F+++ V CF     + CV W     + G WC K
Sbjct:    1 YPGTLWCGPGTNANSFDELGSYKKTDICCREHDHCPHAIGGFEHKYGYNNIGWHTISHCDCDTKFRKCMKESNDTAAWDIGRTYFSIVGVPCFTLREDEACVDWSWWAGIDGEWCLK 117
[Close]
BLAST of Phospholipase A2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008222.1 (pep scaffold:Pmarinus_7.0:GL489691:3482:6078:1 gene:ENSPMAG00000007437.1 transcript:ENSPMAT00000008222.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.1586 bits (152), Expect = 1.805e-13
Identity = 30/66 (45.45%), Postives = 37/66 (56.06%), Query Frame = 3 
Query:  408 YPGTKWCGPGNIAENESDFG----EEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCD 593
            YPGT WCG GN A+N    G    E  ETD+CC +HD C+  I A   K+  +N   HT+  C CD
Sbjct:    4 YPGTLWCGAGNSADNFDQLGAPTGEFEETDRCCRDHDHCEHVIDAFRYKYGHRNLRWHTISHCACD 69
[Close]
BLAST of Phospholipase A2 vs. Ensembl Nematostella
Match: EDO41374 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4S7])

HSP 1 Score: 91.2781 bits (225), Expect = 2.139e-23
Identity = 41/94 (43.62%), Postives = 55/94 (58.51%), Query Frame = 3 
Query:  411 PGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFK--NKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCF 686
            PGTKWCG GNIA++ SD G    TD CC  HD+C   I   ++  T+   N   +++  C CD  FY CL  V +  +  VG +FFN+L+V CF
Sbjct:    1 PGTKWCGAGNIADSHSDLGHHRMTDACCRTHDRCPHSIPPLQVSKTYNYFNFRPYSISHCKCDQAFYACLASVGSNAAKDVGKVFFNILKVPCF 94
[Close]
BLAST of Phospholipase A2 vs. Ensembl Nematostella
Match: EDO47530 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM30])

HSP 1 Score: 75.0998 bits (183), Expect = 1.912e-17
Identity = 39/90 (43.33%), Postives = 54/90 (60.00%), Query Frame = 3 
Query:  405 IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDN-RVSDKVGNLFFNVL 671
            I+PGT WCG GN A+N  D GE  +TD+CC EHD C  +I   E K+ F N    TL+ C C+   + CL  VD+ + +  VG ++FN +
Sbjct:    1 IFPGTNWCGSGNDAKNFDDLGEFNKTDQCCREHDYCPNWIPPFERKFDFFNFSPFTLLDCKCETRLFNCLWGVDDEQAAIFVGRMYFNYI 90
[Close]
BLAST of Phospholipase A2 vs. Ensembl Medaka
Match: pla2g3 (group 3 secretory phospholipase A2-like [Source:NCBI gene;Acc:105355175])

HSP 1 Score: 90.8929 bits (224), Expect = 3.509e-20
Identity = 49/119 (41.18%), Postives = 67/119 (56.30%), Query Frame = 3 
Query:  336 RKLKQTDTIYETSK--RKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCF 686
            R ++  D   E S   R KR     I PGT WCG GN A +  D G   +TD CC EHD+C+  I + + ++   N    T+  C CDD F+ CLKE ++ +SD VG  FFN+L++ CF
Sbjct:  131 RSVRGDDGGSEVSAHLRVKRGF---IVPGTLWCGSGNKAPSFEDLGVFSDTDSCCREHDQCQHTILSFQSEFGVFNSNIFTMSHCDCDDRFHGCLKEANDSISDVVGYTFFNLLKMHCF 246
[Close]
BLAST of Phospholipase A2 vs. Ensembl Medaka
Match: pla2g3 (group 3 secretory phospholipase A2-like [Source:NCBI gene;Acc:105355175])

HSP 1 Score: 90.8929 bits (224), Expect = 3.964e-20
Identity = 42/94 (44.68%), Postives = 58/94 (61.70%), Query Frame = 3 
Query:  405 IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCF 686
            I PGT WCG GN A +  D G   +TD CC EHD+C+  I + + ++   N    T+  C CDD F+ CLKE ++ +SD VG  FFN+L++ CF
Sbjct:  182 IVPGTLWCGSGNKAPSFEDLGVFSDTDSCCREHDQCQHTILSFQSEFGVFNSNIFTMSHCDCDDRFHGCLKEANDSISDVVGYTFFNLLKMHCF 275
[Close]
BLAST of Phospholipase A2 vs. Ensembl Medaka
Match: proca1 (protein interacting with cyclin A1 [Source:NCBI gene;Acc:101162698])

HSP 1 Score: 90.8929 bits (224), Expect = 4.601e-20
Identity = 48/140 (34.29%), Postives = 75/140 (53.57%), Query Frame = 3 
Query:  336 RKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQR 755
            R+   T    +++K  +RS     YPGT WCG GN+A++ +  GE  +TD CC  HD C+  I      + + N    ++  C CD+    CL++V++  S  VG  FFNVL V CF+    + CV  +  G+ C+ Y++
Sbjct:  122 REFSSTSRQNQSAKASRRSKRGFTYPGTLWCGAGNMADHYNQLGEFAQTDSCCRTHDHCQHVIHPFSSNFGYTNFKWLSISHCDCDETLKECLRKVNDTSSRVVGQAFFNVLTVPCFEFAYEEQCVERHWYGL-CKGYKK 260
[Close]
BLAST of Phospholipase A2 vs. Ensembl Medaka
Match: ENSORLT00000015007.2 (group 3 secretory phospholipase A2 [Source:NCBI gene;Acc:101173712])

HSP 1 Score: 86.2705 bits (212), Expect = 1.270e-18
Identity = 44/106 (41.51%), Postives = 56/106 (52.83%), Query Frame = 3 
Query:  378 RKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQRE 695
            R+KRS L   +PGT WCG G+ A      G     D CC EHD C+  I A  + +   N    T+  C CD  F  CLK +++ VS  +G  FF+VLQV CF  E
Sbjct:  135 RRKRSWL---FPGTLWCGTGSRARGYDQLGMFERADVCCREHDHCQHSIPALSVSYGVFNHHFFTVSHCNCDQRFRQCLKRMNDSVSSMIGYTFFSVLQVPCFDSE 237
[Close]
BLAST of Phospholipase A2 vs. Planmine SMEST
Match: SMESG000048503.1 (SMESG000048503.1)

HSP 1 Score: 474.937 bits (1221), Expect = 8.405e-172
Identity = 230/230 (100.00%), Postives = 230/230 (100.00%), Query Frame = 3 
Query:  105 MRSRRLPIPIMKLYHSLTVFCTIICLTKSIEYPRELDGISKNISKPERIFITNDETGNLLLKKLWLNPGQKLNTITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQRQLGIKLYNSQNWN 794
            MRSRRLPIPIMKLYHSLTVFCTIICLTKSIEYPRELDGISKNISKPERIFITNDETGNLLLKKLWLNPGQKLNTITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQRQLGIKLYNSQNWN
Sbjct:    1 MRSRRLPIPIMKLYHSLTVFCTIICLTKSIEYPRELDGISKNISKPERIFITNDETGNLLLKKLWLNPGQKLNTITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQRQLGIKLYNSQNWN 230
[Close]
BLAST of Phospholipase A2 vs. Planmine SMEST
Match: SMESG000048503.1 (SMESG000048503.1)

HSP 1 Score: 452.981 bits (1164), Expect = 3.058e-163
Identity = 220/220 (100.00%), Postives = 220/220 (100.00%), Query Frame = 3 
Query:  135 MKLYHSLTVFCTIICLTKSIEYPRELDGISKNISKPERIFITNDETGNLLLKKLWLNPGQKLNTITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQRQLGIKLYNSQNWN 794
            MKLYHSLTVFCTIICLTKSIEYPRELDGISKNISKPERIFITNDETGNLLLKKLWLNPGQKLNTITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQRQLGIKLYNSQNWN
Sbjct:    1 MKLYHSLTVFCTIICLTKSIEYPRELDGISKNISKPERIFITNDETGNLLLKKLWLNPGQKLNTITERKLKQTDTIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQRQLGIKLYNSQNWN 220
[Close]
BLAST of Phospholipase A2 vs. Planmine SMEST
Match: SMESG000048502.1 (SMESG000048502.1)

HSP 1 Score: 219.164 bits (557), Expect = 4.997e-71
Identity = 95/146 (65.07%), Postives = 118/146 (80.82%), Query Frame = 3 
Query:  357 TIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQRQLGIKLYNSQNWN 794
            TI  T KR KRSILQ+I+PGTKWCGPGNIA+NE+D+GEEIE DKCC  HD+C   I +G+ KW FKNK S+TLM CGCDDEFYLCLKE +   SDK+G LFFN ++++CFQ EVI TC+SWY+ G+WCR+  R+LG+KLY++  WN
Sbjct:   76 TINSTFKRTKRSILQRIFPGTKWCGPGNIAQNENDYGEEIEADKCCQVHDRCPNSIRSGDTKWNFKNKLSYTLMECGCDDEFYLCLKEANTEASDKIGKLFFNFVRMECFQTEVINTCLSWYIPGVWCRRKGRRLGVKLYHANPWN 221
[Close]
BLAST of Phospholipase A2 vs. Planmine SMEST
Match: SMESG000048502.1 (SMESG000048502.1)

HSP 1 Score: 219.55 bits (558), Expect = 7.743e-71
Identity = 95/146 (65.07%), Postives = 118/146 (80.82%), Query Frame = 3 
Query:  357 TIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQRQLGIKLYNSQNWN 794
            TI  T KR KRSILQ+I+PGTKWCGPGNIA+NE+D+GEEIE DKCC  HD+C   I +G+ KW FKNK S+TLM CGCDDEFYLCLKE +   SDK+G LFFN ++++CFQ EVI TC+SWY+ G+WCR+  R+LG+KLY++  WN
Sbjct:  102 TINSTFKRTKRSILQRIFPGTKWCGPGNIAQNENDYGEEIEADKCCQVHDRCPNSIRSGDTKWNFKNKLSYTLMECGCDDEFYLCLKEANTEASDKIGKLFFNFVRMECFQTEVINTCLSWYIPGVWCRRKGRRLGVKLYHANPWN 247
[Close]
BLAST of Phospholipase A2 vs. Planmine SMEST
Match: SMESG000048502.1 (SMESG000048502.1)

HSP 1 Score: 219.164 bits (557), Expect = 1.009e-70
Identity = 95/146 (65.07%), Postives = 118/146 (80.82%), Query Frame = 3 
Query:  357 TIYETSKRKKRSILQKIYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFKNKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIKTCVSWYVIGIWCRKYQRQLGIKLYNSQNWN 794
            TI  T KR KRSILQ+I+PGTKWCGPGNIA+NE+D+GEEIE DKCC  HD+C   I +G+ KW FKNK S+TLM CGCDDEFYLCLKE +   SDK+G LFFN ++++CFQ EVI TC+SWY+ G+WCR+  R+LG+KLY++  WN
Sbjct:   98 TINSTFKRTKRSILQRIFPGTKWCGPGNIAQNENDYGEEIEADKCCQVHDRCPNSIRSGDTKWNFKNKLSYTLMECGCDDEFYLCLKEANTEASDKIGKLFFNFVRMECFQTEVINTCLSWYIPGVWCRRKGRRLGVKLYHANPWN 243
The following BLAST results are available for this feature:
BLAST of Phospholipase A2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
PLA2G32.243e-2238.13phospholipase A2 group III [Source:HGNC Symbol;Acc... [more]
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BLAST of Phospholipase A2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Phospholipase A2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG30096.191e-2441.58gene:FBgn0029720 transcript:FBtr0332316[more]
CG422374.761e-2342.72gene:FBgn0250862 transcript:FBtr0340302[more]
CG30095.175e-2341.58gene:FBgn0029720 transcript:FBtr0070688[more]
CG30095.175e-2341.58gene:FBgn0029720 transcript:FBtr0300468[more]
CG422371.204e-2242.72gene:FBgn0250862 transcript:FBtr0073722[more]
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BLAST of Phospholipase A2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
proca13.046e-2440.00protein interacting with cyclin A1 [Source:ZFIN;Ac... [more]
pla2g38.497e-1938.58phospholipase A2 group III [Source:ZFIN;Acc:ZDB-GE... [more]
CU459012.11.134e-1632.85group 3 secretory phospholipase A2-like [Source:NC... [more]
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BLAST of Phospholipase A2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
uri11.406e-2438.69URI1 prefoldin-like chaperone [Source:Xenbase;Acc:... [more]
ENSXETT00000036327.14.686e-2038.32pep primary_assembly:Xenopus_tropicalis_v9.1:1:131... [more]
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BLAST of Phospholipase A2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Pla2g39.789e-2237.59phospholipase A2, group III [Source:MGI Symbol;Acc... [more]
Pla2g31.366e-2137.59phospholipase A2, group III [Source:MGI Symbol;Acc... [more]
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BLAST of Phospholipase A2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P16354|PA23_HELSU7.973e-2542.86Phospholipase A2 isozymes PA3A/PA3B/PA5 OS=Heloder... [more]
sp|Q7M4I5|PA2_APIDO4.359e-2445.92Phospholipase A2 OS=Apis dorsata OX=7462 PE=1 SV=1[more]
sp|P80003|PA2A2_HELSU1.633e-2343.69Acidic phospholipase A2 PA4 OS=Heloderma suspectum... [more]
sp|Q9BMK4|PA2_APICC2.518e-2344.90Phospholipase A2 OS=Apis cerana cerana OX=94128 PE... [more]
sp|I7GQA7|PA2_XYLAI8.920e-2241.53Phospholipase A(2) OS=Xylocopa appendiculata circu... [more]
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BLAST of Phospholipase A2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Y2KMI81.650e-2940.41Phospholipase A2 OS=Araneus ventricosus OX=182803 ... [more]
A0A0C9S3A54.578e-2835.80TSA: Tityus bahiensis Tbah00274 mRNA sequence (Fra... [more]
A0A2I9LPG11.608e-2646.15Phospholipase A2 OS=Centruroides hentzi OX=88313 P... [more]
A0A087UYP22.859e-2644.54Phospholipase A2 (Fragment) OS=Stegodyphus mimosar... [more]
A0A218QXE23.746e-2635.23Putative phospholipase A2 (Fragment) OS=Tityus ser... [more]
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BLAST of Phospholipase A2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
proca15.603e-2441.73uncharacterized LOC103023370 [Source:NCBI gene;Acc... [more]
proca12.343e-2340.63uncharacterized LOC103023370 [Source:NCBI gene;Acc... [more]
ENSAMXT00000053537.14.845e-1536.13uncharacterized LOC103036138 [Source:NCBI gene;Acc... [more]
ENSAMXT00000057577.11.315e-835.53pep primary_assembly:Astyanax_mexicanus-2.0:20:581... [more]
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BLAST of Phospholipase A2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000005482.15.019e-2338.46pep scaffold:Pmarinus_7.0:GL479025:28110:33430:-1 ... [more]
ENSPMAT00000008222.11.805e-1345.45pep scaffold:Pmarinus_7.0:GL489691:3482:6078:1 gen... [more]
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BLAST of Phospholipase A2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Phospholipase A2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO413742.139e-2343.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO475301.912e-1743.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Phospholipase A2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
pla2g33.509e-2041.18group 3 secretory phospholipase A2-like [Source:NC... [more]
pla2g33.964e-2044.68group 3 secretory phospholipase A2-like [Source:NC... [more]
proca14.601e-2034.29protein interacting with cyclin A1 [Source:NCBI ge... [more]
ENSORLT00000015007.21.270e-1841.51group 3 secretory phospholipase A2 [Source:NCBI ge... [more]
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BLAST of Phospholipase A2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000048503.18.405e-172100.00SMESG000048503.1[more]
SMESG000048503.13.058e-163100.00SMESG000048503.1[more]
SMESG000048502.14.997e-7165.07SMESG000048502.1[more]
SMESG000048502.17.743e-7165.07SMESG000048502.1[more]
SMESG000048502.11.009e-7065.07SMESG000048502.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026339 ID=SMED30026339|Name=Phospholipase A2|organism=Schmidtea mediterranea sexual|type=transcript|length=893bp
TGTTTATTATTTGTCATTTTAATAAGCATGAAAATGACAATAGACTTATG
ACACGTCATTATTTCGCCGTGTAATCCATTAACTTTCAATCAAAATATTC
TAAAATGCGATCGCGACGCTTGCCAATACCAATAATGAAGCTTTATCATT
CCTTAACCGTATTCTGTACAATTATTTGTCTAACCAAATCCATTGAATAC
CCCAGAGAATTGGATGGCATATCTAAAAATATATCTAAACCAGAGAGGAT
TTTTATTACAAACGATGAGACAGGAAATCTTTTATTGAAAAAATTGTGGT
TAAACCCAGGTCAAAAGCTCAATACAATTACAGAAAGAAAATTAAAACAA
ACAGACACAATTTACGAGACTTCAAAGAGAAAAAAGAGAAGCATTCTTCA
AAAGATATATCCTGGAACAAAATGGTGTGGTCCAGGAAACATTGCTGAAA
ACGAATCGGATTTTGGGGAAGAAATTGAGACCGACAAATGTTGCCACGAA
CATGATAAATGCAAAATGTTCATTGGAGCTGGAGAAATTAAATGGACTTT
TAAAAACAAATTCTCCCATACTTTGATGTCATGCGGATGTGATGATGAAT
TTTATCTTTGCTTAAAAGAAGTCGACAATCGAGTTTCCGACAAAGTCGGA
AATCTATTTTTCAATGTCCTTCAGGTGAAATGTTTCCAGAGAGAAGTGAT
AAAAACTTGTGTTTCTTGGTATGTAATTGGAATCTGGTGTCGGAAATATC
AGCGCCAATTAGGGATAAAACTATACAATTCACAAAATTGGAATTAGTTT
GCTAAAGATCTCATGATTTTCTAGGATAACTAAAATCTGATTTCTTTTTC
TAATATAATTTGATTTGTTTATATTTGCAGAAGCGCGAAGTTG
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protein sequence of SMED30026339-orf-1

>SMED30026339-orf-1 ID=SMED30026339-orf-1|Name=SMED30026339-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=231bp
MRSRRLPIPIMKLYHSLTVFCTIICLTKSIEYPRELDGISKNISKPERIF
ITNDETGNLLLKKLWLNPGQKLNTITERKLKQTDTIYETSKRKKRSILQK
IYPGTKWCGPGNIAENESDFGEEIETDKCCHEHDKCKMFIGAGEIKWTFK
NKFSHTLMSCGCDDEFYLCLKEVDNRVSDKVGNLFFNVLQVKCFQREVIK
TCVSWYVIGIWCRKYQRQLGIKLYNSQNWN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000418head
PLANA:0002075pigment cell
PLANA:0002089reproductive organ
PLANA:0002142parenchyma
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036444PLipase_A2_dom_sf
IPR016090PLipase_A2_dom
IPR033113PLipase_A2_His_AS
Vocabulary: molecular function
TermDefinition
GO:0004623phospholipase A2 activity
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
Vocabulary: biological process
TermDefinition
GO:0006644phospholipid metabolic process
GO:0050482arachidonic acid secretion
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR016090Phospholipase A2 domainPFAMPF05826Phospholip_A2_2coord: 101..196
e-value: 2.6E-34
score: 117.3
IPR036444Phospholipase A2 domain superfamilyGENE3DG3DSA:1.20.90.10coord: 100..228
e-value: 1.9E-37
score: 130.1
IPR036444Phospholipase A2 domain superfamilySUPERFAMILYSSF48619Phospholipase A2, PLA2coord: 101..215
NoneNo IPR availablePANTHERPTHR12253FAMILY NOT NAMEDcoord: 68..225
IPR033113Phospholipase A2, histidine active sitePROSITEPS00118PA2_HIScoord: 129..136