Actin-related protein 2/3 complex subunit 5

Overview


Name	Actin-related protein 2/3 complex subunit 5
Smed ID	SMED30026316
Length (bp)	693

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Actin-related protein 2/3 complex subunit 5 (SMED30026316) t-SNE clustered cells

Violin plots show distribution of expression levels for Actin-related protein 2/3 complex subunit 5 (SMED30026316) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Actin-related protein 2/3 complex subunit 5 (SMED30026316) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Actin-related protein 2/3 complex subunit 5 (SMED30026316) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30026316

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
protonephridia	SMED30026316	SMESG000023170.1	dd_Smed_v4_781_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30026316	SMESG000023170.1	dd_Smed_v4_781_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30026316	SMESG000023170.1	dd_Smed_v4_781_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30026316	SMESG000023170.1	dd_Smed_v4_781_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Human
Match: ARPC5L (actin related protein 2/3 complex subunit 5 like [Source:HGNC Symbol;Acc:HGNC:23366])

HSP 1 Score: 113.62 bits (283), Expect = 2.903e-31
Identity = 57/153 (37.25%), Postives = 91/153 (59.48%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEIS----DSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FR+VD+D F +N F D+Q E  +       +  EV  L+     L A    L  +P  + NQA+K++A  ++ +++ +FKS++I+  V+ L+   +D+L+KY+YK FE P ENS+ +LL WH+        G ++RVLT RK V
Sbjct:    1 MARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGVDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV 153

[Close]

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEIS----DSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FR+VD+D F +N F D+Q E  +       +  EV  L+     L A    L  +P  + NQA+K++A  ++ +++ +FKS++I+  V+ L+   +D+L+KY+YK FE P ENS+ +LL WH+        G ++RVLT RK V
Sbjct:    1 MARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGVDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV 153

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Human
Match: ARPC5 (actin related protein 2/3 complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:708])

HSP 1 Score: 110.538 bits (275), Expect = 4.680e-30
Identity = 53/142 (37.32%), Postives = 87/142 (61.27%), Query Frame = 3

Query:  138 KFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            +FRKVDVD + +N F D++   +     +E EV + +       AL+  L   P  + +QA+KD+A  I+ ++++SFK+N I+  V+ L++  +D+L+KY+YK FE P +NS+ +LL WH+        G ++RVLT RK V
Sbjct:   10 RFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAMLLQWHEKALAAGGVGSIVRVLTARKTV 151

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Human
Match: ARPC5 (actin related protein 2/3 complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:708])

HSP 1 Score: 108.612 bits (270), Expect = 2.832e-29
Identity = 54/145 (37.24%), Postives = 92/145 (63.45%), Query Frame = 3

Query:  138 KFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLV--ALSKNL-EALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            +FRKVDVD + +N F D++   +     +E EV + +  +++ N+  AL+  L   P  + +QA+KD+A  I+ ++++SFK+N I+  V+ L++  +D+L+KY+YK FE P +NS+ +LL WH+        G ++RVLT RK V
Sbjct:   10 RFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRHSITGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAMLLQWHEKALAAGGVGSIVRVLTARKTV 154

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Human
Match: ARPC5 (actin related protein 2/3 complex subunit 5 [Source:HGNC Symbol;Acc:HGNC:708])

HSP 1 Score: 97.0561 bits (240), Expect = 4.673e-25
Identity = 45/123 (36.59%), Postives = 78/123 (63.41%), Query Frame = 3

Query:  138 KFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCI 503
            +FRKVDVD + +N F D++   +     +E EV + +       AL+  L   P  + +QA+KD+A  I+ ++++SFK+N I+  V+ L++  +D+L+KY+YK FE P +NS+ +LL WH+ +
Sbjct:   10 RFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAMLLQWHEKV 132

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BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Celegans
Match: arx-7 (Actin-related protein 2/3 complex subunit 5 [Source:UniProtKB/TrEMBL;Acc:O61861])

HSP 1 Score: 84.7297 bits (208), Expect = 1.503e-20
Identity = 48/154 (31.17%), Postives = 92/154 (59.74%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEISDSIN----EQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVL-LLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            M+ N ++  +RK+DVD F    +  D+++E  D+      E+ V   ++ ++  +AL   L   P  + +Q +KD+A +++++++ SFK+ +I+ TV++L+  E DIL+KYVYK+ E   + +    LL WH  +  +  +G +MRV + R+R+
Sbjct:    1 MSKNMQNTSYRKLDVDSFDPEQY--DENDETVDTPGLGPDERAVQGFLSSNRLEDALHAALLSPPLKTKDQNVKDRATQLVTKVLQSFKNAEIEATVQKLSIEESDILMKYVYKSMEIGADAAVCQSLLAWHAQLVAKFGHGAIMRVFSGRQRL 152

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BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Celegans
Match: C46H11.3 (Probable actin-related protein 2/3 complex subunit 5 [Source:UniProtKB/Swiss-Prot;Acc:P91167])

HSP 1 Score: 83.1889 bits (204), Expect = 6.043e-20
Identity = 46/141 (32.62%), Postives = 82/141 (58.16%), Query Frame = 3

Query:  141 FRKVDVDLFSDNNFKDDQSEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVL-LLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            ++K +VD+F   +F+D Q E      N QEV   +  ++   AL+ VL   P   S Q LK++A  +++ +I +F+   I+ +V +L+    DIL+KY+YKA +   +++  L LL WH  +  +   G ++RVL++R+R+
Sbjct:    6 YKKYNVDIFHPAHFEDIQEESADCGPNVQEVRQFLESNRLEYALQSVLLNPPFGHSEQELKNRAVLLVAEVIHAFRQTDIEESVHKLSNENGDILMKYIYKAMQLCSDSATCLSLLLWHSQLVSKFGQGSIVRVLSNRQRL 146

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BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Fly
Match: Arpc5 (gene:FBgn0031437 transcript:FBtr0335170)

HSP 1 Score: 123.635 bits (309), Expect = 1.897e-35
Identity = 60/151 (39.74%), Postives = 94/151 (62.25%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFK-DDQSEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETEL-DILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  N FRK+DVD ++++NF+ DD  E  +   +E E++ L+   K++EAL   L  AP    NQ +KD A  I  R+++S KS Q+   ++ L++ +L D+L+KY+Y+ FE P E S+  LL WH+  + +   GC++RVL+D  R 
Sbjct:    1 MAKNTSSNAFRKIDVDQYNEDNFREDDGVESAAAGPDESEITTLLTQGKSVEALLSALQNAPLRCKNQNVKDHALNITLRVLLSIKSTQMDQAIDTLDQNDLIDVLMKYIYRGFEIPSEGSSGHLLQWHEKAFAKGGVGCIVRVLSDTNRA 151

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Fly
Match: Arpc5 (gene:FBgn0031437 transcript:FBtr0077694)

HSP 1 Score: 123.635 bits (309), Expect = 1.897e-35
Identity = 60/151 (39.74%), Postives = 94/151 (62.25%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFK-DDQSEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETEL-DILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  N FRK+DVD ++++NF+ DD  E  +   +E E++ L+   K++EAL   L  AP    NQ +KD A  I  R+++S KS Q+   ++ L++ +L D+L+KY+Y+ FE P E S+  LL WH+  + +   GC++RVL+D  R 
Sbjct:    1 MAKNTSSNAFRKIDVDQYNEDNFREDDGVESAAAGPDESEITTLLTQGKSVEALLSALQNAPLRCKNQNVKDHALNITLRVLLSIKSTQMDQAIDTLDQNDLIDVLMKYIYRGFEIPSEGSSGHLLQWHEKAFAKGGVGCIVRVLSDTNRA 151

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BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Zebrafish
Match: arpc5lb (actin related protein 2/3 complex, subunit 5-like, b [Source:ZFIN;Acc:ZDB-GENE-060531-161])

HSP 1 Score: 126.716 bits (317), Expect = 1.510e-36
Identity = 60/150 (40.00%), Postives = 93/150 (62.00%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEI-SDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FRKVD+D F +N F DD  E       +  EV NL+     + AL + L   P  S N A+K++A  ++ R++ SFKS+ I+  V+ L++  +D+L+KY+YK FE P +NS+ +LL WH+ ++     GC++RV+T RK V
Sbjct:    1 MAKNTLSSRFRKVDIDEFDENKFVDDHDEAADQQGPDALEVDNLLRQGDTMSALHIALRNPPIHSKNPAIKERAQTVVFRVLTSFKSSDIEPAVKSLDKNGVDLLMKYIYKGFERPTDNSSAILLQWHEKVFAAGGLGCIVRVMTARKSV 150

[Close]

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEI-SDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FRKVD+D F +N F DD  E       +  EV NL+     + AL + L   P  S N A+K++A  ++ R++ SFKS+ I+  V+ L++  +D+L+KY+YK FE P +NS+ +LL WH+ ++     GC++RV+T RK V
Sbjct:    1 MAKNTLSSRFRKVDIDEFDENKFVDDHDEAADQQGPDALEVDNLLRQGDTMSALHIALRNPPIHSKNPAIKERAQTVVFRVLTSFKSSDIEPAVKSLDKNGVDLLMKYIYKGFERPTDNSSAILLQWHEKVFAAGGLGCIVRVMTARKSV 150

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Zebrafish
Match: arpc5b (actin related protein 2/3 complex, subunit 5B [Source:ZFIN;Acc:ZDB-GENE-040120-7])

HSP 1 Score: 118.627 bits (296), Expect = 1.846e-33
Identity = 60/150 (40.00%), Postives = 93/150 (62.00%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            M+ NT  ++FRKVDVD + +N F D++   E     +E EV +L+     + AL+ VL   P  + NQ +KD+A  ++ +++ SFKS  I+  V+ L++  +D+L+KY+YK FE P ENS+ +LL WH+        GC++RVLT RK V
Sbjct:    1 MSKNTVSDRFRKVDVDEYDENKFVDEEEGGENQLGPDEAEVDSLIRQGNLMGALQAVLKNPPINTKNQNVKDRAEGLVLKVLSSFKSTDIEKGVQSLDKNGVDLLMKYIYKGFERPSENSSAVLLQWHEKALSAGGVGCIVRVLTARKTV 150

[Close]

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            M+ NT  ++FRKVDVD + +N F D++   E     +E EV +L+     + AL+ VL   P  + NQ +KD+A  ++ +++ SFKS  I+  V+ L++  +D+L+KY+YK FE P ENS+ +LL WH+        GC++RVLT RK V
Sbjct:    1 MSKNTVSDRFRKVDVDEYDENKFVDEEEGGENQLGPDEAEVDSLIRQGNLMGALQAVLKNPPINTKNQNVKDRAEGLVLKVLSSFKSTDIEKGVQSLDKNGVDLLMKYIYKGFERPSENSSAVLLQWHEKALSAGGVGCIVRVLTARKTV 150

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BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Zebrafish
Match: arpc5a (actin related protein 2/3 complex, subunit 5A [Source:ZFIN;Acc:ZDB-GENE-030131-8448])

HSP 1 Score: 115.546 bits (288), Expect = 3.379e-32
Identity = 58/150 (38.67%), Postives = 94/150 (62.67%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            M+ NT  ++FRKVDVD + +N F D++   E     +E EV +L+     + AL+ VL   P  + NQ +KD+A  ++ +++ SFK++ I+  V+ L++T +D+L+KY+YK FE P +NS+ +LL WH+        G ++RVLT RK V
Sbjct:    1 MSKNTVSDRFRKVDVDEYDENKFVDEEDGGENQLGPDEAEVDSLIRSGNLMGALQAVLKNPPIHTKNQNVKDRAEGLVLKVLSSFKASDIEKAVQSLDKTGVDLLMKYIYKGFERPSDNSSAILLQWHEKALSAGGVGSIVRVLTARKTV 150

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Xenopus
Match: arpc5 (actin related protein 2/3 complex subunit 5 [Source:NCBI gene;Acc:549996])

HSP 1 Score: 117.087 bits (292), Expect = 1.079e-32
Identity = 57/150 (38.00%), Postives = 93/150 (62.00%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT   +FRKVDVD + +N F D++ + E     +E EV + +     + AL+  L   P  + NQ+ KD+A  ++ ++++SFK+N I+  V+ L++  +D+L+KY+YK FE P +NS+ +LL WH+     +  G ++RVLT RK V
Sbjct:    1 MAKNTVSARFRKVDVDEYDENKFVDEEEAGEGQQGPDEGEVDSAIRGGNMMGALQAALKNPPINTKNQSAKDRAEHLVLKVLISFKANDIEKAVQSLDKNNMDLLMKYIYKGFESPSDNSSAVLLQWHEKALAVAGVGSIVRVLTARKTV 150

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Xenopus
Match: mknk1 (MAP kinase interacting serine/threonine kinase 1 [Source:Xenbase;Acc:XB-GENE-979969])

HSP 1 Score: 117.087 bits (292), Expect = 1.272e-32
Identity = 61/152 (40.13%), Postives = 90/152 (59.21%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEIS---DSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FRKVD+D + +N F DDQ +E        +E EV +L+     L A +  L  +P  S NQ +K++   I+ +++ SFKSN I+  V  L+   +D+L+KY+YK FE P ENS+ +LL WH+        G ++RVLT RK V
Sbjct:    1 MAKNTLSSRFRKVDIDEYDENKFVDDQLQEEPAEPQGPDEAEVDSLIRQGDLLRAFQSALRNSPVNSKNQVVKERTQAIVLKVLTSFKSNDIEKAVNTLDPNGIDLLMKYIYKGFEKPTENSSAILLQWHEKALVIGGLGSIVRVLTSRKTV 152

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Mouse
Match: Arpc5l (actin related protein 2/3 complex, subunit 5-like [Source:MGI Symbol;Acc:MGI:1921442])

HSP 1 Score: 110.538 bits (275), Expect = 3.948e-30
Identity = 56/153 (36.60%), Postives = 90/153 (58.82%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEISDSINEQ----EVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FR+VD+D F +N F D+  E  + +        EV  L+     L A    L  +P  + NQA+K++A  ++ +++ +FKS++I+  V+ L+   +D+L+KY+YK FE P ENS+ +LL WH+        G ++RVLT RK V
Sbjct:    1 MARNTLSSRFRRVDIDEFDENKFVDEHEEAAAAAGEPGPDPCEVDGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV 153

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Mouse
Match: Arpc5 (actin related protein 2/3 complex, subunit 5 [Source:MGI Symbol;Acc:MGI:1915021])

HSP 1 Score: 109.768 bits (273), Expect = 5.495e-30
Identity = 53/142 (37.32%), Postives = 87/142 (61.27%), Query Frame = 3

Query:  138 KFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            +FRKVDVD + +N F D++   +     +E EV + +       AL+  L   P  + +QA+KD+A  I+ ++++SFK+N I+  V+ L++  +D+L+KY+YK FE P +NS+ +LL WH+        G ++RVLT RK V
Sbjct:   10 RFRKVDVDEYDENKFVDEEDGGDGQAGPDEGEVDSCLRQGNMTAALQAALKNPPINTKSQAVKDRAGSIVLKVLISFKANDIEKAVQSLDKNGVDLLMKYIYKGFESPSDNSSAVLLQWHEKALAAGGVGSIVRVLTARKTV 151

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. UniProt/SwissProt
Match: sp|Q641B9|APC5C_XENLA (Actin-related protein 2/3 complex subunit 5-C OS=Xenopus laevis OX=8355 GN=arpc5-c PE=2 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 6.250e-34
Identity = 59/150 (39.33%), Postives = 95/150 (63.33%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT   +FRKVDVD + +N F D++ + E     +E EV + +     + AL+ VL   P  + NQ+ KDQA  ++ ++++SFK+N+I+  V+ L++  +D+L+KY+YK FE P +NS+ +LL WH+     +  G ++RVLT RK V
Sbjct:    1 MAKNTVSARFRKVDVDEYDENKFVDEEEAGEGQQGPDEGEVDSAIRGGNMMGALQAVLKNPPINTKNQSAKDQAEHLVLKVLISFKANEIEKAVQSLDKNSMDLLMKYIYKGFESPSDNSSAVLLQWHEKALAVAGVGSIVRVLTARKTV 150

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. UniProt/SwissProt
Match: sp|Q6DE18|APC5B_XENLA (Actin-related protein 2/3 complex subunit 5-B OS=Xenopus laevis OX=8355 GN=arpc5-b PE=1 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 5.247e-33
Identity = 62/152 (40.79%), Postives = 94/152 (61.84%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQ-SEEISD--SINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FRKVD+D + +N F DDQ  EE ++    +E EV +L+   + L A +  L  +P  S NQ  K++   I+ +++ SFKSN+I+  V  L+   +D+L+KY+YK FE P ENS+ +LL WH+  +     G ++RVLT RK V
Sbjct:    1 MAKNTLSSRFRKVDIDEYDENKFVDDQLQEEPAEPQGPDEAEVDSLIRQGELLRAFQSALRNSPVNSKNQVAKERTQAIVLKVLTSFKSNEIEKAVNTLDPNGIDLLMKYIYKGFEKPTENSSAILLQWHEKAFVIGGLGSIVRVLTSRKTV 152

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. UniProt/SwissProt
Match: sp|Q68FI4|APC5A_XENLA (Actin-related protein 2/3 complex subunit 5-A OS=Xenopus laevis OX=8355 GN=arpc5-a PE=2 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 6.715e-32
Identity = 57/150 (38.00%), Postives = 93/150 (62.00%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT   +FRKVDVD + +N F D++ + E     +E EV + +     + AL+  L   P  + NQ+ KD+A  ++ ++++SFK+N+I+  V+ L++   D+L+KY+YK FE P +NS+ +LL WH+     +  G ++RVLT RK V
Sbjct:    1 MAKNTVSARFRKVDVDEYDENKFVDEEEAGEGQQGPDEGEVDSAIRGGNMMGALQAALKNPPINTKNQSAKDRAENLVLKVLISFKANEIEKAVQSLDKNSTDLLMKYIYKGFESPSDNSSAVLLQWHEKALAVAGVGSIVRVLTARKTV 150

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. UniProt/SwissProt
Match: sp|A1L108|ARP5L_RAT (Actin-related protein 2/3 complex subunit 5-like protein OS=Rattus norvegicus OX=10116 GN=Arpc5l PE=1 SV=2)

HSP 1 Score: 115.931 bits (289), Expect = 2.033e-31
Identity = 58/153 (37.91%), Postives = 90/153 (58.82%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEISDSINEQ----EVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FR+VD+D F +N F D+  E  + S        EV  L+     L A    L  +P  + NQA+K++A  I+ +++ +FKS++I+  V+ L+   +D+L+KY+YK FE P ENS+ +LL WH+        G ++RVLT RK V
Sbjct:    1 MARNTLSSRFRRVDIDEFDENKFVDEHEEAAAASGEPGPDPCEVDGLLRQGDMLRAFHAALRNSPINTKNQAVKERAQGIVLKVLTNFKSSEIEQAVQSLDRNGIDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV 153

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. UniProt/SwissProt
Match: sp|Q5R4M1|ARP5L_PONAB (Actin-related protein 2/3 complex subunit 5-like protein OS=Pongo abelii OX=9601 GN=ARPC5L PE=2 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.394e-30
Identity = 57/153 (37.25%), Postives = 91/153 (59.48%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEIS----DSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FR+VD+D F +N F D+Q E  +       +  EV  L+     L A    L  +P  + NQA+K++A  ++ +++ +FKS++I+  V+ L+   +D+L+KY+YK FE P ENS+ +LL WH+        G ++RVLT RK V
Sbjct:    1 MARNTLSSRFRRVDIDEFDENKFVDEQEEAAAAAAEPGPDPSEVDGLLRQGDMLRAFHAALRNSPVNTKNQAVKERAQGVVLKVLTNFKSSEIEQAVQSLDRNGVDLLMKYIYKGFEKPTENSSAVLLQWHEKALAVGGLGSIIRVLTARKTV 153

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. TrEMBL
Match: A0A1S3HX18 (Actin-related protein 2/3 complex subunit 5 OS=Lingula unguis OX=7574 GN=LOC106158245 PE=3 SV=1)

HSP 1 Score: 155.992 bits (393), Expect = 1.234e-44
Identity = 71/150 (47.33%), Postives = 108/150 (72.00%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEISD-SINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            M+ NT DNKFRK+DVD ++++N++D+ +++  D   NEQEVS+ ++  KNLEAL+ VLS  P  + NQA KD+A +++ R+++SFK   I   V  L+   LD+L+KY+Y+ FE+P E S+  LLTWH+ +++   YGC+MRVLT RK+V
Sbjct:    1 MSKNTADNKFRKIDVDQYNEDNYQDEVADDGQDMGPNEQEVSSFLSQGKNLEALQAVLSNPPVETKNQAAKDRALQLVMRVLLSFKVADIDKGVNALDSQTLDVLMKYIYRGFENPSEGSSAQLLTWHEKVFEIGGYGCIMRVLTQRKKV 150

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. TrEMBL
Match: A0A1S3HUB2 (Actin-related protein 2/3 complex subunit 5 OS=Lingula unguis OX=7574 GN=LOC106158245 PE=3 SV=1)

HSP 1 Score: 151.754 bits (382), Expect = 6.366e-43
Identity = 70/150 (46.67%), Postives = 107/150 (71.33%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEISD-SINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            M+ NT DNKFRK+DVD ++++N++D+ +++  D   NEQEVS+ ++  KNLEAL+ VLS  P  + NQA KD+A +++ R+++SFK   I   V  L+   LD+L+KY+Y+ FE+P E S+  LLTWH+  +++   GC++RVLTDRK V
Sbjct:    1 MSKNTADNKFRKIDVDQYNEDNYQDEVADDGQDMGPNEQEVSSFLSQGKNLEALQAVLSNPPVETKNQAAKDRALQLVMRVLLSFKVADIDKGVNALDSQTLDVLMKYIYRGFENPSEGSSAQLLTWHEKSFKKGGLGCIVRVLTDRKMV 150

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. TrEMBL
Match: A0A183IXT8 (Actin-related protein 2/3 complex subunit 5 OS=Soboliphyme baturini OX=241478 GN=SBAD_LOCUS8436 PE=3 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 5.563e-41
Identity = 63/151 (41.72%), Postives = 110/151 (72.85%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEISDSI--NEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NTR   FRK+DVD ++++ +KD+  E+ + ++  +E+EV+ L+ +++N+EALK+ L   P  + NQALKD+A +++ R++ SF+   I++ V+ L++ ++D+++KY+YK FE P + S+ +LL WHD +YQ    GC++RVLTDR+R+
Sbjct:    1 MAKNTRSTAFRKIDVDAYNEDQYKDEDQEQDATTVGPDEEEVTKLLQMNRNVEALKMALKNPPLKTRNQALKDRATQLVVRVLCSFRQADIESAVQSLDKDQIDLIMKYIYKGFEFPQDGSSSVLLAWHDKVYQVGGNGCIVRVLTDRRRL 151

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. TrEMBL
Match: A0A0P6EM95 (Actin-related protein 2/3 complex subunit 5 OS=Daphnia magna OX=35525 PE=3 SV=1)

HSP 1 Score: 141.354 bits (355), Expect = 6.278e-39
Identity = 66/152 (43.42%), Postives = 104/152 (68.42%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDD---QSEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  + FRK+DVD ++++N+K+D   +S+      +E+E++N +   KN+EALK VL  AP +S NQ +KD A  ++ ++++S KS+QI+  V  L+   LDIL+KY+Y+ FE P E S+  LL WH+ ++  +  GC++RVLTD+KRV
Sbjct:    1 MAKNTSSSAFRKIDVDQYNEDNYKEDDCGESQSPPVGPDEKEITNFINQGKNIEALKTVLRNAPISSRNQMIKDAALNVVMQVLLSVKSSQIEEAVNALDRDHLDILMKYIYRGFETPSEGSSGQLLAWHEKVHAVAGVGCIVRVLTDKKRV 152

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. TrEMBL
Match: A0A4S2KHS1 (Actin-related protein 2/3 complex subunit 5 OS=Opisthorchis felineus OX=147828 GN=CRM22_010941 PE=3 SV=1)

HSP 1 Score: 140.969 bits (354), Expect = 8.523e-39
Identity = 68/151 (45.03%), Postives = 106/151 (70.20%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEISDS-INEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPEN-SNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT D KFRKVDVD ++++ F+D+Q+++ S + +NE +V  L+  +K  EAL LVL  AP  S +QALKD A++ + R++   K+  I   V  L+E ++D+L+KY+Y+ FE  P++ +N  LLTWH+ ++ R K GC++RVLTDR+R+
Sbjct:    1 MAKNTGDTKFRKVDVDQYTESAFQDEQADDSSATKLNEFDVRGLLEKAKFDEALALVLQNAPINSKDQALKDTAFRYVMRLLSQIKAQNIDEFVAGLDEPKIDLLMKYIYRGFEQQPQDTTNATLLTWHEKVHARGKSGCIIRVLTDRRRI 151

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Cavefish
Match: arpc5b (actin related protein 2/3 complex subunit 5 [Source:NCBI gene;Acc:103045524])

HSP 1 Score: 120.553 bits (301), Expect = 3.813e-34
Identity = 60/150 (40.00%), Postives = 95/150 (63.33%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            M+ NT  ++FRKVDVD + +N F D++   E     +E EV +L+     +EAL+ VL   P  + NQ +KD+A  ++ +++ SFK++ I+  V+ L++  +D+L+KY+YK FE P ENS+ +LL WH+        GC++RVLT RK V
Sbjct:    1 MSKNTVSDRFRKVDVDEYDENKFVDEEDGGENQLGPDEAEVDSLIRQGNLMEALQAVLKNPPINTKNQNVKDRAEGLVLKVLSSFKASDIEKGVQSLDKNGVDLLMKYIYKGFERPSENSSAILLQWHEKALSAGGVGCIVRVLTARKTV 150

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Cavefish
Match: arpc5la (actin-related protein 2/3 complex subunit 5-like protein [Source:NCBI gene;Acc:103043418])

HSP 1 Score: 111.309 bits (277), Expect = 1.182e-30
Identity = 54/150 (36.00%), Postives = 89/150 (59.33%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEI-SDSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FR +D+D + +N F D+Q E       +  EV  L+   + + A  + L   P  S N A+K++A  ++ R++ SFKS+ I+  V+ L+   +D+L+KY+Y+ FE P +NS+ +LL WH+  +     G ++RVLT RK V
Sbjct:    1 MARNTLPSRFRGLDIDEYDENRFVDEQDEAAEQQGPDGAEVDALLRRGEMITAFHIALRNPPINSKNPAVKERAQAVVLRVLTSFKSSDIEPAVKSLDRNGVDLLMKYIYRGFEKPSDNSSAILLQWHEKAFAVGGLGSIVRVLTARKSV 150

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Cavefish
Match: arpc5a (actin related protein 2/3 complex, subunit 5A [Source:ZFIN;Acc:ZDB-GENE-030131-8448])

HSP 1 Score: 104.375 bits (259), Expect = 6.130e-28
Identity = 58/152 (38.16%), Postives = 92/152 (60.53%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLEALK--LVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            M+ NT  ++FRKVDVD + +N F D++   E     +E EV +L+        LK   VL   P  + NQ +KD+A  ++ +++ +FKS+ I+  V+ L++ ++D+L+KY+YK FE P ENS+ +LL WH+        G ++RVLT RK V
Sbjct:    1 MSKNTVSDRFRKVDVDEYDENKFVDEEDGGENQLGPDEAEVDSLI----RQYPLKHSAVLKNPPINTKNQNVKDRAEGLVLKVLTAFKSSDIEKAVQSLDKNKVDLLMKYIYKGFERPSENSSAVLLQWHEKALSAGGVGSIVRVLTARKTV 148

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Cavefish
Match: arpc5lb (actin related protein 2/3 complex, subunit 5-like, b [Source:ZFIN;Acc:ZDB-GENE-060531-161])

HSP 1 Score: 99.3673 bits (246), Expect = 5.650e-26
Identity = 53/158 (33.54%), Postives = 90/158 (56.96%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNN-FKDDQSEEIS-DSINEQEVSNLV-------ALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  ++FR+V+VD   +++ F ++Q E       +  EV +L+            + A  + L   P  S N A+K++A  ++ R++ SFKS+ I+  V+ ++   +D+L+KY+YK FE P ENS+ +LL WH+  +     G ++RV+T RK V
Sbjct:    1 MARNTLGSRFRRVEVDGLEESSRFVEEQDEAAELQGPDTAEVDSLLRQYPAAAVCGDMMSAFHVALRNPPINSKNPAIKEKAQAVVLRVLTSFKSSDIEPAVKSIDRNGIDLLMKYIYKGFEKPCENSSAILLQWHEKAFAVGGLGSIVRVMTSRKTV 158

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Sea Lamprey
Match: arpc5la (actin related protein 2/3 complex, subunit 5-like, a [Source:ZFIN;Acc:ZDB-GENE-040426-1453])

HSP 1 Score: 111.309 bits (277), Expect = 3.018e-31
Identity = 58/155 (37.42%), Postives = 90/155 (58.06%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEISDSINEQEVSNLVALSKN------LEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            MA NT  N+FRKVDVD + +N F D + EE ++     E     AL         + ALK  L   P  S +Q++K++A   + +++ +FK+  ++  V  L++  +D+L++YVYK FE P ENS+ +LL WH+ +      GC++RVLT RK V
Sbjct:    1 MAKNTMSNRFRKVDVDEYDENKFVD-EPEEAAEQQGPDEAEVDAALRTRASTGDMIAALKAALKNPPLNSKSQSVKERAEGTVLKVLTAFKAADMERGVRSLDQGSVDLLMQYVYKGFERPSENSSAVLLQWHEKVLAVGGLGCVVRVLTARKMV 154

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Yeast
Match: ARC15 (Subunit of the ARP2/3 complex; ARP2/3 is required for the motility and integrity of cortical actin patches; has mRNA binding activity [Source:SGD;Acc:S000001324])

HSP 1 Score: 52.7582 bits (125), Expect = 2.336e-9
Identity = 36/151 (23.84%), Postives = 74/151 (49.01%), Query Frame = 3

Query:  141 FRKVDVDLFSDNNFK---DDQSEEISDSINEQEVS-------NLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDP-PENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            +R++D+D F   + +    D       ++  QE+        +L     +L A++L L+  P  S++   K+Q +K +   +   +   I N ++ L++++ D+L+KY+YK    P  +    +LL W + I Q S    ++  ++DR+ V
Sbjct:    5 WRRIDIDAFDPESGRLTAADLVPPYETTVTLQELQPRMNQLRSLATSGDSLGAVQL-LTTDPPYSADAPTKEQYFKSVLEALTQVRQADIGNVIKNLSDSQRDVLVKYLYKGMSVPQGQKQGGVLLAWLERITQVSGVTPIVHYISDRRTV 154

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Nematostella
Match: EDO44235 (Actin-related protein 2/3 complex subunit 5 [Source:UniProtKB/TrEMBL;Acc:A7RWB9])

HSP 1 Score: 126.331 bits (316), Expect = 6.389e-37
Identity = 59/150 (39.33%), Postives = 100/150 (66.67%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEIS-DSINEQEVSNLVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            M+ +++  +FRKVD+D   +N F D+Q +E      +E EV++L+   KN EALK VL+  P  S NQA+KD+A++++ +++ + +SN+I N ++ L ++E+DIL+KY+Y+ F  P ENS  +LL WH+ +      G ++R LT+RK +
Sbjct:    1 MSKSSQSTQFRKVDIDELDENRFDDEQVDEGGMTGPDEGEVNSLLMSKKNGEALKAVLANPPVLSKNQAVKDKAFQLVLKVLTTTRSNEIDNALKGLTKSEVDILMKYIYRGFAQPNENSCGILLNWHEKVLAAGGLGSIIRGLTERKSI 150

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Medaka
Match: arpc5b (actin related protein 2/3 complex subunit 5 [Source:NCBI gene;Acc:101173455])

HSP 1 Score: 105.145 bits (261), Expect = 3.697e-28
Identity = 57/154 (37.01%), Postives = 93/154 (60.39%), Query Frame = 3

Query:  114 MAVNTRDNKFRKVDVDLFSDNNFKDDQ-SEEISDSINEQEVSNLVALSKNLE----ALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            M+ NT   +FR+VDVD + +N F D++   E     +E EV +L+    + +    AL+ VL   P  + NQ +KD+A  ++ +++ +FKS+ I+  V+ L++  +D+L+KY+YK FE P ENS+ +LL WH+        G ++RVLT RK V
Sbjct:    1 MSKNTVSARFRRVDVDEYDENKFVDEEDGGENQIGPDEAEVDSLIRQYPSDDMLAYALQAVLKNPPINTKNQNVKDRAEGLVLKVLSAFKSSDIEKGVQSLDKNGVDLLMKYIYKGFERPSENSSAVLLQWHEKALAAGGVGSIVRVLTARKTV 154

[Close]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Planmine SMEST
Match: SMESG000023170.1 (SMESG000023170.1)

HSP 1 Score: 214.927 bits (546), Expect = 6.299e-72
Identity = 103/107 (96.26%), Postives = 105/107 (98.13%), Query Frame = 3

Query:  240 LVALSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 560
            ++  SKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV
Sbjct:    1 MIVSSKNLEALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETELDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV 107

The following BLAST results are available for this feature:

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Human
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Celegans
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Fly
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Zebrafish
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Xenopus
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Mouse
BLAST of Actin-related protein 2/3 complex subunit 5 vs. UniProt/SwissProt
BLAST of Actin-related protein 2/3 complex subunit 5 vs. TrEMBL
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Cavefish
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Sea Lamprey
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Yeast
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Nematostella
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Medaka
BLAST of Actin-related protein 2/3 complex subunit 5 vs. Planmine SMEST

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ARPC5L	2.903e-31	37.25	actin related protein 2/3 complex subunit 5 like [...	[more]
ARPC5L	2.903e-31	37.25	actin related protein 2/3 complex subunit 5 like [...	[more]
ARPC5	4.680e-30	37.32	actin related protein 2/3 complex subunit 5 [Sourc...	[more]
ARPC5	2.832e-29	37.24	actin related protein 2/3 complex subunit 5 [Sourc...	[more]
ARPC5	4.673e-25	36.59	actin related protein 2/3 complex subunit 5 [Sourc...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
arx-7	1.503e-20	31.17	Actin-related protein 2/3 complex subunit 5 [Sour...	[more]
C46H11.3	6.043e-20	32.62	Probable actin-related protein 2/3 complex subunit...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Arpc5	1.897e-35	39.74	gene:FBgn0031437 transcript:FBtr0335170	[more]
Arpc5	1.897e-35	39.74	gene:FBgn0031437 transcript:FBtr0077694	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arpc5lb	1.510e-36	40.00	actin related protein 2/3 complex, subunit 5-like,...	[more]
arpc5lb	1.510e-36	40.00	actin related protein 2/3 complex, subunit 5-like,...	[more]
arpc5b	1.846e-33	40.00	actin related protein 2/3 complex, subunit 5B [Sou...	[more]
arpc5b	1.846e-33	40.00	actin related protein 2/3 complex, subunit 5B [Sou...	[more]
arpc5a	3.379e-32	38.67	actin related protein 2/3 complex, subunit 5A [Sou...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
arpc5	1.079e-32	38.00	actin related protein 2/3 complex subunit 5 [Sourc...	[more]
mknk1	1.272e-32	40.13	MAP kinase interacting serine/threonine kinase 1 [...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Arpc5l	3.948e-30	36.60	actin related protein 2/3 complex, subunit 5-like ...	[more]
Arpc5	5.495e-30	37.32	actin related protein 2/3 complex, subunit 5 [Sour...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q641B9\|APC5C_XENLA	6.250e-34	39.33	Actin-related protein 2/3 complex subunit 5-C OS=X...	[more]
sp\|Q6DE18\|APC5B_XENLA	5.247e-33	40.79	Actin-related protein 2/3 complex subunit 5-B OS=X...	[more]
sp\|Q68FI4\|APC5A_XENLA	6.715e-32	38.00	Actin-related protein 2/3 complex subunit 5-A OS=X...	[more]
sp\|A1L108\|ARP5L_RAT	2.033e-31	37.91	Actin-related protein 2/3 complex subunit 5-like p...	[more]
sp\|Q5R4M1\|ARP5L_PONAB	1.394e-30	37.25	Actin-related protein 2/3 complex subunit 5-like p...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S3HX18	1.234e-44	47.33	Actin-related protein 2/3 complex subunit 5 OS=Lin...	[more]
A0A1S3HUB2	6.366e-43	46.67	Actin-related protein 2/3 complex subunit 5 OS=Lin...	[more]
A0A183IXT8	5.563e-41	41.72	Actin-related protein 2/3 complex subunit 5 OS=Sob...	[more]
A0A0P6EM95	6.278e-39	43.42	Actin-related protein 2/3 complex subunit 5 OS=Dap...	[more]
A0A4S2KHS1	8.523e-39	45.03	Actin-related protein 2/3 complex subunit 5 OS=Opi...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
arpc5b	3.813e-34	40.00	actin related protein 2/3 complex subunit 5 [Sourc...	[more]
arpc5la	1.182e-30	36.00	actin-related protein 2/3 complex subunit 5-like p...	[more]
arpc5a	6.130e-28	38.16	actin related protein 2/3 complex, subunit 5A [Sou...	[more]
arpc5lb	5.650e-26	33.54	actin related protein 2/3 complex, subunit 5-like,...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
arpc5la	3.018e-31	37.42	actin related protein 2/3 complex, subunit 5-like,...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
ARC15	2.336e-9	23.84	Subunit of the ARP2/3 complex; ARP2/3 is required ...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO44235	6.389e-37	39.33	Actin-related protein 2/3 complex subunit 5 [Sour...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1


Match Name	E-value	Identity	Description
arpc5b	3.697e-28	37.01	actin related protein 2/3 complex subunit 5 [Sourc...	[more]

BLAST of Actin-related protein 2/3 complex subunit 5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000023170.1	6.299e-72	96.26	SMESG000023170.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30026316 ID=SMED30026316|Name=Actin-related protein 2/3 complex subunit 5|organism=Schmidtea mediterranea sexual|type=transcript|length=693bp
CTTTTTTGTTTTAAAGATTGATTGGTATTTATAAGATTTCAAATTACAGG
AAAATATTATTCAATAATTAAATTTAATTTGTAAATCTAAATCAATTGTT
CAGTAATTTTTCTATGGCAGTCAATACAAGAGACAATAAATTTCGAAAGG
TTGATGTTGATTTATTCAGTGACAACAATTTTAAAGATGATCAATCGGAA
GAGATTTCTGATTCCATTAATGAACAGGAAGTTTCAAATCTAGTTGCACT
TTCTAAAAATTTAGAAGCTCTGAAATTAGTTCTTTCAAAGGCCCCAACTG
CATCAAGTAATCAAGCCCTGAAGGATCAAGCATATAAAATTATATCTAGA
ATAATCGTTTCATTTAAGTCCAACCAAATTAAAAATACAGTTGAAGAGCT
TAATGAAACAGAATTAGATATTTTATTGAAATACGTTTACAAAGCATTTG
AAGATCCGCCAGAAAATAGCAATGTACTGTTATTGACTTGGCACGATTGC
ATCTACCAAAGAAGCAAATACGGTTGTATGATGAGAGTCTTGACCGATAG
GAAACGAGTTTAAAACGATTTGCAAATAGAAAAACGAATACAAATTATAA
TTTCGTGTGATTTATAAAAATTCTTCATGCTGAAATTCTTCAATATCGAA
ATAAATAAAATTTAATTATTTATTATGTAATTTTAATTCTGGC

protein sequence of SMED30026316-orf-1

>SMED30026316-orf-1 ID=SMED30026316-orf-1|Name=SMED30026316-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=150bp
MAVNTRDNKFRKVDVDLFSDNNFKDDQSEEISDSINEQEVSNLVALSKNL
EALKLVLSKAPTASSNQALKDQAYKIISRIIVSFKSNQIKNTVEELNETE
LDILLKYVYKAFEDPPENSNVLLLTWHDCIYQRSKYGCMMRVLTDRKRV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0002032	epidermal cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036743	ARPC5_sf
IPR030075	ARPC5L
IPR006789	ARPC5

Vocabulary: **cellular component**
Term	Definition
GO:0005885	Arp2/3 protein complex
GO:0015629	actin cytoskeleton
GO:0005856	cytoskeleton

Vocabulary: **biological process**
Term	Definition
GO:0034314	Arp2/3 complex-mediated actin nucleation
GO:0030833	regulation of actin filament polymerization

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR036743	Actin-related protein 2/3 complex subunit 5 superfamily	GENE3D	G3DSA:1.25.40.190		coord: 1..149 e-value: 3.6E-42 score: 146.0
IPR036743	Actin-related protein 2/3 complex subunit 5 superfamily	SUPERFAMILY	SSF69103	Arp2/3 complex 16 kDa subunit ARPC5	coord: 9..149
IPR006789	Actin-related protein 2/3 complex subunit 5	PFAM	PF04699	P16-Arc	coord: 9..149 e-value: 1.3E-37 score: 129.6
IPR006789	Actin-related protein 2/3 complex subunit 5	PANTHER	PTHR12644	ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC	coord: 1..149
IPR030075	Actin-related protein 2/3 complex subunit 5-like protein	PANTHER	PTHR12644:SF2	ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 5-LIKE PROTEIN	coord: 1..149