Parathyroid hormone/parathyroid hormone peptide receptor

Overview
NameParathyroid hormone/parathyroid hormone peptide receptor
Smed IDSMED30026220
Length (bp)1397
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Parathyroid hormone/parathyroid hormone peptide receptor (SMED30026220) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Parathyroid hormone/parathyroid hormone peptide receptor (SMED30026220) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30026220

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30026220h1SMcG0007441 SmedASXL_014163SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30026220h1SMcG0007441 dd_Smed_v4_16180_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30026220h1SMcG0007441 dd_Smed_v4_16180_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30026220h1SMcG0007441 dd_Smed_v4_16180_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30026220h1SMcG0007441 dd_Smed_v4_16180_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30026220h1SMcG0007441 dd_Smed_v4_16180_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30026220h1SMcG0007441 dd_Smed_v6_16180_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30026220h1SMcG0007441 Contig41486newmark_estsPMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30026220h1SMcG0007441 Contig41486uc_Smed_v2PMID:28434803
Rouhana et al., 2017
whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Human
Match: PTH1R (parathyroid hormone 1 receptor [Source:HGNC Symbol;Acc:HGNC:9608])

HSP 1 Score: 146.362 bits (368), Expect = 6.817e-38
Identity = 113/415 (27.23%), Postives = 194/415 (46.75%), Query Frame = 1
Query:   64 VTISQEEQHESVYGKL-------QECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWL------------------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
             + S + + +   GKL       +E    SRY       C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F       S   L                              CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  +  GW +P +   VW +++    N  CW +     K   W+  +  + + ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +          S +   VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   72 ASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRP---CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTV-FGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK---WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEV---SGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 476          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Human
Match: PTH1R (parathyroid hormone 1 receptor [Source:HGNC Symbol;Acc:HGNC:9608])

HSP 1 Score: 144.821 bits (364), Expect = 4.371e-37
Identity = 113/415 (27.23%), Postives = 194/415 (46.75%), Query Frame = 1
Query:   64 VTISQEEQHESVYGKL-------QECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWL------------------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
             + S + + +   GKL       +E    SRY       C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F       S   L                              CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  +  GW +P +   VW +++    N  CW +     K   W+  +  + + ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +          S +   VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   72 ASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRP---CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTV-FGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK---WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTE---VSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 476          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Human
Match: PTH1R (parathyroid hormone 1 receptor [Source:HGNC Symbol;Acc:HGNC:9608])

HSP 1 Score: 144.821 bits (364), Expect = 4.371e-37
Identity = 113/415 (27.23%), Postives = 194/415 (46.75%), Query Frame = 1
Query:   64 VTISQEEQHESVYGKL-------QECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWL------------------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
             + S + + +   GKL       +E    SRY       C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F       S   L                              CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  +  GW +P +   VW +++    N  CW +     K   W+  +  + + ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +          S +   VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   72 ASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRP---CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTV-FGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK---WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTE---VSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 476          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Human
Match: PTH1R (parathyroid hormone 1 receptor [Source:HGNC Symbol;Acc:HGNC:9608])

HSP 1 Score: 144.821 bits (364), Expect = 4.371e-37
Identity = 113/415 (27.23%), Postives = 194/415 (46.75%), Query Frame = 1
Query:   64 VTISQEEQHESVYGKL-------QECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWL------------------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
             + S + + +   GKL       +E    SRY       C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F       S   L                              CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  +  GW +P +   VW +++    N  CW +     K   W+  +  + + ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +          S +   VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   72 ASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRP---CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTV-FGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK---WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTE---VSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 476          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Human
Match: PTH1R (parathyroid hormone 1 receptor [Source:HGNC Symbol;Acc:HGNC:9608])

HSP 1 Score: 144.821 bits (364), Expect = 4.371e-37
Identity = 113/415 (27.23%), Postives = 194/415 (46.75%), Query Frame = 1
Query:   64 VTISQEEQHESVYGKL-------QECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWL------------------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
             + S + + +   GKL       +E    SRY       C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F       S   L                              CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  +  GW +P +   VW +++    N  CW +     K   W+  +  + + ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +          S +   VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   72 ASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRP---CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTV-FGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK---WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTE---VSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 476          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Celegans
Match: seb-3 (SEcretin/class B GPCR; Secretin receptor-like protein SEB-3 [Source:UniProtKB/TrEMBL;Acc:G5EBF7])

HSP 1 Score: 86.6557 bits (213), Expect = 4.509e-18
Identity = 105/453 (23.18%), Postives = 189/453 (41.72%), Query Frame = 1
Query:   97 VYGKLQECLNLSRYMSSSSD--FCPYDFDKVMCWPPTRPGEIAIQPCPLYI-------NGLRIRGKTTRQCMESGYWRNYTNYENCIS--------------------KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLR-ALTHFFNLIPPSSIV---------------WLCRLFAAIDYLSI---TASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKE----CWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKR--------YYRQRN---DRRTCLNEHSNPLSMIFPER---KSQNIRSNKRAAT 1257
            +  +   C  L +  +SS +   C  DFDK +CW     G+   + CP            ++ R   +R C   G W++ +NY  CI                     + L++  S+  L  V    S+I L  ++++ + F  + C R +IH ++  AF+ R A+   + ++  +++                W+C+   AI +  I    AS  W+ IE  FL++   +  MR +     +Y++ GW +P ++   WA +     +++    CW  Y        W+         ++NL   + I+ +L  K    ++      +R + KAT +LV + GI +   IPL    E  +S     V +     +   QG F+A+L+CF+NSE+   +KR        +++ RN     RT + E  N      P     K++NI S +   +
Sbjct:    5 IRAEYAACQELKKLENSSYNPGGCSVDFDKSLCWASAHIGQQMTRDCPFTFCTAIPGCEEIKDRYMVSRNCNSMGVWQD-SNYTMCIKVVEEYAQCLQGFCRVCPDVLRDLVISVSLT-LSFV----SVILLVAAIVLFSIFDSIQCRRLSIHKNLATAFVFRFAVLAIWTIVQTTNVFQDCTRLTPLPLWDYEWICK---AILWFVIYFNVASVMWMLIEGAFLYSRFTVFAMRHSDAPWSLYLACGWGVPFVVVTAWALVHQYISSQQTNSFCWLPYAQGLH--LWILAGTMGSALIMNLIFLLMIVVILVQKLRTENSAESKKIWRTI-KATLLLVPLLGISN---IPLFYEPEHPSS-----VYMLGSAILQHSQGIFIAVLYCFLNSEIQGALKRQLSKVPFEFFKTRNRFETERTYVPEARNATKNGVPMEEMNKTKNIESGENTES 437          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Celegans
Match: pdfr-1 (Calcitonin receptor-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09460])

HSP 1 Score: 78.1814 bits (191), Expect = 3.160e-15
Identity = 111/444 (25.00%), Postives = 197/444 (44.37%), Query Frame = 1
Query:  157 FCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW--RN----------YTNYENCISKKLI-VIASMNH---------------LGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRA---LTHFFNLI---------------PPSSIVWLCR-LFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVW---ATLKYLYGNKECW-QIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVI-LIPLVLLSEQINSESFEIVQLYYEHTMTSC---QGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNKRA------ATCLTNNNGSNH*KLSVY 1305
            +C   +D V+CWPPT         CP ++ GL      T+ C  SG W  RN          +TN+  C + ++I ++ ++N+               L  VG GLSL+ L +++ + + F++L   RN +HLH+  A L+     L  + +LI                 +++  +C  +F  ++Y   T +  W+F+E ++L+N ++       P  L  +I+ G+ IP +  ++W     +K  +  + C    Y +P    +W+     +   +INL    N+IRVL+ K  + SN       +K  KA  +L+ + G+ +++  IP     + I      +V   + +T +     QG  VA ++CF N EV   +K +Y     R   L++  N L      R S+++ S+  A      A+    NN     KLS +
Sbjct:   73 WCNATYDTVLCWPPTPANSSVTLQCP-HMKGLDPNKNITKDCHVSGVWSGRNAGEMGPTLPGWTNFTMCYTDEVIYIMQNLNNESLTIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFK-TVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIA-GYGIPLVHTMLWLLVVLIKKDFKVERCLGSYYLEPE---FWILDGPRMAELVINLFFICNVIRVLYSKVRE-SNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNI------MVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYA----RYRLLHKSQNEL-----RRGSRSVASHYAAKNGTANASAPQTNNADEFGKLSPF 494          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Celegans
Match: pdfr-1 (Calcitonin receptor-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09460])

HSP 1 Score: 78.1814 bits (191), Expect = 3.160e-15
Identity = 111/444 (25.00%), Postives = 197/444 (44.37%), Query Frame = 1
Query:  157 FCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW--RN----------YTNYENCISKKLI-VIASMNH---------------LGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRA---LTHFFNLI---------------PPSSIVWLCR-LFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVW---ATLKYLYGNKECW-QIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVI-LIPLVLLSEQINSESFEIVQLYYEHTMTSC---QGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNKRA------ATCLTNNNGSNH*KLSVY 1305
            +C   +D V+CWPPT         CP ++ GL      T+ C  SG W  RN          +TN+  C + ++I ++ ++N+               L  VG GLSL+ L +++ + + F++L   RN +HLH+  A L+     L  + +LI                 +++  +C  +F  ++Y   T +  W+F+E ++L+N ++       P  L  +I+ G+ IP +  ++W     +K  +  + C    Y +P    +W+     +   +INL    N+IRVL+ K  + SN       +K  KA  +L+ + G+ +++  IP     + I      +V   + +T +     QG  VA ++CF N EV   +K +Y     R   L++  N L      R S+++ S+  A      A+    NN     KLS +
Sbjct:   73 WCNATYDTVLCWPPTPANSSVTLQCP-HMKGLDPNKNITKDCHVSGVWSGRNAGEMGPTLPGWTNFTMCYTDEVIYIMQNLNNESLTIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFK-TVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIA-GYGIPLVHTMLWLLVVLIKKDFKVERCLGSYYLEPE---FWILDGPRMAELVINLFFICNVIRVLYSKVRE-SNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNI------MVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYA----RYRLLHKSQNEL-----RRGSRSVASHYAAKNGTANASAPQTNNADEFGKLSPF 494          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Celegans
Match: pdfr-1 (Calcitonin receptor-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09460])

HSP 1 Score: 78.1814 bits (191), Expect = 3.583e-15
Identity = 111/444 (25.00%), Postives = 197/444 (44.37%), Query Frame = 1
Query:  157 FCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW--RN----------YTNYENCISKKLI-VIASMNH---------------LGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRA---LTHFFNLI---------------PPSSIVWLCR-LFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVW---ATLKYLYGNKEC-WQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVI-LIPLVLLSEQINSESFEIVQLYYEHTMTSC---QGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNKRA------ATCLTNNNGSNH*KLSVY 1305
            +C   +D V+CWPPT         CP ++ GL      T+ C  SG W  RN          +TN+  C + ++I ++ ++N+               L  VG GLSL+ L +++ + + F++L   RN +HLH+  A L+     L  + +LI                 +++  +C  +F  ++Y   T +  W+F+E ++L+N ++       P  L  +I+ G+ IP +  ++W     +K  +  + C    Y +P    +W+     +   +INL    N+IRVL+ K  + SN       +K  KA  +L+ + G+ +++  IP     + I      +V   + +T +     QG  VA ++CF N EV   +K +Y     R   L++  N L      R S+++ S+  A      A+    NN     KLS +
Sbjct:   73 WCNATYDTVLCWPPTPANSSVTLQCP-HMKGLDPNKNITKDCHVSGVWSGRNAGEMGPTLPGWTNFTMCYTDEVIYIMQNLNNESLTIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFK-TVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIA-GYGIPLVHTMLWLLVVLIKKDFKVERCLGSYYLEPE---FWILDGPRMAELVINLFFICNVIRVLYSKVRE-SNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNI------MVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYA----RYRLLHKSQNEL-----RRGSRSVASHYAAKNGTANASAPQTNNADEFGKLSPF 494          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Celegans
Match: pdfr-1 (Calcitonin receptor-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09460])

HSP 1 Score: 78.1814 bits (191), Expect = 3.583e-15
Identity = 111/444 (25.00%), Postives = 197/444 (44.37%), Query Frame = 1
Query:  157 FCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW--RN----------YTNYENCISKKLI-VIASMNH---------------LGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRA---LTHFFNLI---------------PPSSIVWLCR-LFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVW---ATLKYLYGNKEC-WQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVI-LIPLVLLSEQINSESFEIVQLYYEHTMTSC---QGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNKRA------ATCLTNNNGSNH*KLSVY 1305
            +C   +D V+CWPPT         CP ++ GL      T+ C  SG W  RN          +TN+  C + ++I ++ ++N+               L  VG GLSL+ L +++ + + F++L   RN +HLH+  A L+     L  + +LI                 +++  +C  +F  ++Y   T +  W+F+E ++L+N ++       P  L  +I+ G+ IP +  ++W     +K  +  + C    Y +P    +W+     +   +INL    N+IRVL+ K  + SN       +K  KA  +L+ + G+ +++  IP     + I      +V   + +T +     QG  VA ++CF N EV   +K +Y     R   L++  N L      R S+++ S+  A      A+    NN     KLS +
Sbjct:   73 WCNATYDTVLCWPPTPANSSVTLQCP-HMKGLDPNKNITKDCHVSGVWSGRNAGEMGPTLPGWTNFTMCYTDEVIYIMQNLNNESLTIAQEVARNARKLEFVGLGLSLVSLILAISIFSYFRRLRVFRNLLHLHLMIAMLMVVILRLVLYIDLIFTGENGPHTNSAEGKTINTMPIVCEGMFFFLEYFK-TVTFCWMFLEGIYLNNQIVFGFFNSEPKLLPYFIA-GYGIPLVHTMLWLLVVLIKKDFKVERCLGSYYLEPE---FWILDGPRMAELVINLFFICNVIRVLYSKVRE-SNNTSEAGLKKSVKAAMMLLPLLGVPNIMQTIPFAPTRDNI------MVFAVWTYTASFTYMYQGLMVASIYCFTNKEVNHVLKTFYA----RYRLLHKSQNEL-----RRGSRSVASHYAAKNGTANASAPQTNNADEFGKLSPF 494          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Fly
Match: Dh44-R2 (gene:FBgn0033744 transcript:FBtr0113075)

HSP 1 Score: 111.694 bits (278), Expect = 2.546e-26
Identity = 104/366 (28.42%), Postives = 171/366 (46.72%), Query Frame = 1
Query:  160 CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLR--IRGKTTRQCMESGYWRNYTNYENCISKKLIVIASMNHLGHV---------GYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRA----LTHFFNLIPPSSIVWLC-RLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQI----YDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATD--RSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSN 1191
            CP  FD V+CWP T  G +A+ PC     G+        TR C  +G W +Y++Y+ C      +    +   +V         GY LS   L +++I+   FK L C RNTIH ++F  ++  A    LT F  +I   S    C  L     Y  +T +  W+F+E L+L+  ++     D   +  IY  IGW  P +  +VW+  K    + E         D    R   ++ ++ +  +L  L   + +IR++++  T    ++ L   +Y K  KA  +L+ +FGI    L+ L    + I+   FE ++ +    + S QGFFVAL +CF+NSEV + ++  + +  + R   N H N
Sbjct:   84 CPSSFDSVLCWPRTNAGSLAVLPCFEEFKGVHYDTTDNATRFCFPNGTWDHYSDYDRCHQNSGSIPVVPDFSPNVELPAIIYAGGYFLSFATLVVALIIFLSFKDLRCLRNTIHANLFLTYITSALLWILTLFLQVITTESSQAGCITLVIMFQYFYLT-NFFWMFVEGLYLYTLVVQTFSSDN-ISFIIYALIGWGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAWMRESHIDWIFKVPASLALLVNLVFLIRIMWVLITKLRSAHTLETRQYYKASKALLVLIPLFGI--TYLLVLTGPEQGISRNLFEAIRAF----LISTQGFFVALFYCFLNSEVRQTLRHGFTRWRESR---NIHRN 438          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Fly
Match: Dh44-R2 (gene:FBgn0033744 transcript:FBtr0087936)

HSP 1 Score: 111.694 bits (278), Expect = 2.723e-26
Identity = 104/366 (28.42%), Postives = 171/366 (46.72%), Query Frame = 1
Query:  160 CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLR--IRGKTTRQCMESGYWRNYTNYENCISKKLIVIASMNHLGHV---------GYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRA----LTHFFNLIPPSSIVWLC-RLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQI----YDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATD--RSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSN 1191
            CP  FD V+CWP T  G +A+ PC     G+        TR C  +G W +Y++Y+ C      +    +   +V         GY LS   L +++I+   FK L C RNTIH ++F  ++  A    LT F  +I   S    C  L     Y  +T +  W+F+E L+L+  ++     D   +  IY  IGW  P +  +VW+  K    + E         D    R   ++ ++ +  +L  L   + +IR++++  T    ++ L   +Y K  KA  +L+ +FGI    L+ L    + I+   FE ++ +    + S QGFFVAL +CF+NSEV + ++  + +  + R   N H N
Sbjct:   84 CPSSFDSVLCWPRTNAGSLAVLPCFEEFKGVHYDTTDNATRFCFPNGTWDHYSDYDRCHQNSGSIPVVPDFSPNVELPAIIYAGGYFLSFATLVVALIIFLSFKDLRCLRNTIHANLFLTYITSALLWILTLFLQVITTESSQAGCITLVIMFQYFYLT-NFFWMFVEGLYLYTLVVQTFSSDN-ISFIIYALIGWGCPAVCILVWSIAKAFAPHLENEHFNGLEIDCAWMRESHIDWIFKVPASLALLVNLVFLIRIMWVLITKLRSAHTLETRQYYKASKALLVLIPLFGI--TYLLVLTGPEQGISRNLFEAIRAF----LISTQGFFVALFYCFLNSEVRQTLRHGFTRWRESR---NIHRN 438          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Fly
Match: Dh44-R1 (gene:FBgn0033932 transcript:FBtr0087485)

HSP 1 Score: 109.768 bits (273), Expect = 1.604e-25
Identity = 107/373 (28.69%), Postives = 178/373 (47.72%), Query Frame = 1
Query:  109 LQECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRG--KTTRQCMESGYWRNYTNYENC--------ISKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNL---IPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYL---YGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATD-RSNGLVNNR-YRKLFKATAILVIVFGIYDVILIPLVLLSEQ-INSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRT 1170
            +QE +  S Y  + S  C   FD ++CWP T  G +A+  C   + G+        TR C  +G W  YTNY+ C        + +  +++     + ++GY LSL+ L +++IV   FK+L C RNTIH ++F+ +++ AL     L   I   S V  C     + +     +  W+ +E L+L+  ++     D      IY SIGW  P +  + WA  K L   Y   E ++I + P  +   ++ +Y      + +     ++R++++  T  RS   V  R YRK  KA  +L+ +FGI    L+ L   SE  +    F +++      + S QGF V+L +CF+NSEV   ++ +     D RT
Sbjct:   37 VQEHIEASTY-GNDSGHCLTQFDSILCWPRTARGTLAVLQCMDELQGIHYDSSKNATRFCHANGTWEKYTNYDACAHLPAPESVPEFEVIVELPTIIYYIGYTLSLVSLSLALIVFAYFKELRCLRNTIHANLFFTYIMSALFWILLLSVQISIRSGVGSCIALITLFHFFTLTNFFWMLVEGLYLYMLVVKTFSGDN-LRFNIYASIGWGGPALFVVTWAVAKSLTVTYSTPEKYEI-NCPWMQETHVDWIYQGPVCAVLIINLTFLLRIMWVLITKLRSANTVETRQYRKAAKALLVLIPLFGI--TYLVVLAGPSESGLMGHMFAVLRA----VLLSTQGFSVSLFYCFLNSEVRNALRHHISTWRDTRT 400          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Fly
Match: Pdfr (gene:FBgn0260753 transcript:FBtr0070436)

HSP 1 Score: 96.2857 bits (238), Expect = 7.197e-21
Identity = 103/374 (27.54%), Postives = 170/374 (45.45%), Query Frame = 1
Query:  157 FCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYWRN-----------YTNYENCISKKLIVIASMNHLGH------------------VGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRA---LTHFFN--------------LIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNK---EC-WQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVI--LIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEV 1122
            +C + +D ++CWPPT  G +A   CP   +G+  R    R+C   G W +           +T+Y  C   ++I +  M  +G                   VG  LSL  L +S+++   F+ L   R  IH ++F A +L+    LT + +              L    +  +LC     +   + TA   W+FIE L+LHN + + + + + + L  +  +GW +P ++  VWA    +Y +    EC W     P+   YW+     +   L+N    +NIIRVL MK   +S      + RK  +A  +L+ + GI +++  L PL        + +   V  Y  H +TS QGFF+AL++CF+N EV
Sbjct:  146 YCNWTWDTLLCWPPTPAGVLARMNCPGGFHGVDTRKFAIRKCELDGRWGSRPNATEVNPPGWTDYGPCYKPEIIRL--MQQMGSKDFDAYIDIARRTRTLEIVGLCLSLFALIVSLLIFCTFRSLRNNRTKIHKNLFVAMVLQVIIRLTLYLDQFRRGNKEAATNTSLSVIENTPYLCEASYVLLEYARTAMFMWMFIEGLYLHNMVTVAVFQGS-FPLKFFSRLGWCVPILMTTVWARCTVMYMDTSLGECLWNYNLTPY---YWILEGPRLAVILLNFCFLVNIIRVLVMK-LRQSQASDIEQTRKAVRAAIVLLPLLGITNLLHQLAPL-------KTATNFAVWSYGTHFLTSFQGFFIALIYCFLNGEV 505          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Fly
Match: hec (gene:FBgn0030437 transcript:FBtr0343652)

HSP 1 Score: 95.1301 bits (235), Expect = 9.264e-21
Identity = 101/345 (29.28%), Postives = 166/345 (48.12%), Query Frame = 1
Query:  157 FCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCIS-KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLR--ALTHFFNLIPPSS------IVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYG--NKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVK 1137
            FCP +FD  +CWP T  G +  Q CP ++ G   +    + C+E+G W       + ++NY NC+  + L     +N L   GY LSL+ L IS+I+   FK L C R  IH+H+F +      A   ++ L+   S       +W   L   + Y  +  ++ W+F E L LH  L++  ++DT   +  +I I W  P  + IV+   ++     NK CW I D  +    W+  +   L+ L +    IN++RV+  K   +S        RK  +AT ILV +FG+   +L        Q++   ++++ +     + S QGF V+ LFCF N +V   ++
Sbjct:  119 FCPLNFDGYLCWPRTPAGTVLSQYCPDFVEGFNRKFLAHKTCLENGSWYRHPVSNQTWSNYTNCVDYEDLEFRQFINELYVKGYALSLLALLISIIIFLGFKSLRCTRIRIHVHLFASLACTCVAWILWYRLVVERSETIAENPLWCIGLHLVVHYFML-VNYFWMFCEGLHLHLVLVVVFVKDT-IVMRWFIVISWFSPIPIAIVYGLARHFSSPDNKHCW-ITDSLY---LWIFSVPITLSLLASFIFLINVLRVIVRKLHPQSAQPAPLAIRKAVRATIILVPLFGLQHFLLPYRPDAGTQLD-HFYQMLSV----VLVSLQGFVVSFLFCFANHDVTFAIR 452          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Zebrafish
Match: pth1r (parathyroid hormone 1 receptor [Source:ZFIN;Acc:ZDB-GENE-991123-8])

HSP 1 Score: 146.362 bits (368), Expect = 4.263e-38
Identity = 108/408 (26.47%), Postives = 205/408 (50.25%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNL--SRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI--------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLI-------------------------PPSSIVWL--CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQR 1155
            +++EEQ   ++   ++C     S++ +S     P ++D ++CWP   PG++    CP YI     +G   R+C  +G W       + + NY  C         +++  V   +  +  VGY +SL  L ++ +++  F++L C RN IH+H+F +F+LRA++ F   +                         PP++      C++   +    +  ++ W+ +E L+LH+ + +    D  Y  G  + IGW +P +   +WA+++    + ECW   D     + W+  +  +   ++N  LF+NIIRVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ + +     +++   ++I Q++YE    S QGFFVA+++CF N EV  E+K+ + +R
Sbjct:    7 LTKEEQIYLLFNAKRKCERAIKSKHKTSEGSCLP-EWDGILCWPEGVPGKMVSTSCPEYIYDFNHKGHAYRRCDLNGTWELASHNNKTWANYSECAKFFPHYNQNQEREVFDRLYLIYTVGYSISLGSLMVATVILGYFRRLHCTRNYIHMHLFLSFMLRAISIFVKDVVLYSGSALQEMERITVEDLKSITEAPPANKTQFIGCKVAVTLFLYFLATNYYWILVEGLYLHSLIFMTFFSDRKYLWGFTL-IGWGVPAMFVTIWASVRATLADTECW---DLSAGNLKWIVQIPILTAIVVNFLLFLNIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAMPY--TEVSGVLWQI-QMHYEMLFNSVQGFFVAIIYCFCNGEVQAEIKKAWNRR 406          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Zebrafish
Match: pth1r (parathyroid hormone 1 receptor [Source:ZFIN;Acc:ZDB-GENE-991123-8])

HSP 1 Score: 146.362 bits (368), Expect = 4.474e-38
Identity = 108/408 (26.47%), Postives = 205/408 (50.25%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNL--SRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI--------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLI-------------------------PPSSIVWL--CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQR 1155
            +++EEQ   ++   ++C     S++ +S     P ++D ++CWP   PG++    CP YI     +G   R+C  +G W       + + NY  C         +++  V   +  +  VGY +SL  L ++ +++  F++L C RN IH+H+F +F+LRA++ F   +                         PP++      C++   +    +  ++ W+ +E L+LH+ + +    D  Y  G  + IGW +P +   +WA+++    + ECW   D     + W+  +  +   ++N  LF+NIIRVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ + +     +++   ++I Q++YE    S QGFFVA+++CF N EV  E+K+ + +R
Sbjct:   32 LTKEEQIYLLFNAKRKCERAIKSKHKTSEGSCLP-EWDGILCWPEGVPGKMVSTSCPEYIYDFNHKGHAYRRCDLNGTWELASHNNKTWANYSECAKFFPHYNQNQEREVFDRLYLIYTVGYSISLGSLMVATVILGYFRRLHCTRNYIHMHLFLSFMLRAISIFVKDVVLYSGSALQEMERITVEDLKSITEAPPANKTQFIGCKVAVTLFLYFLATNYYWILVEGLYLHSLIFMTFFSDRKYLWGFTL-IGWGVPAMFVTIWASVRATLADTECW---DLSAGNLKWIVQIPILTAIVVNFLLFLNIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAMPY--TEVSGVLWQI-QMHYEMLFNSVQGFFVAIIYCFCNGEVQAEIKKAWNRR 431          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Zebrafish
Match: pth2rb (parathyroid hormone 2 receptor b [Source:ZFIN;Acc:ZDB-GENE-050208-334])

HSP 1 Score: 145.976 bits (367), Expect = 1.542e-37
Identity = 117/456 (25.66%), Postives = 211/456 (46.27%), Query Frame = 1
Query:   64 VTISQEEQHESVYGKLQECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-----RNYTNYENCI--------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF-------------------FNLIPPSSIVWL-------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNKRAATCLTNNNGSNH*KLSVYT 1308
            V ++ +EQ   +Y    +CL      + + + C   +D ++CWP   PG +   PCP Y+      G   RQC  +G W     R + NY +C+          K      ++ +  VGY +S   L +++ ++  F++L C RN IH+H+F +F+LRA++ F                    + I   SI  L       C++        +  ++ W+ +E L+LH+ + +    D+ Y  G  + IGW +P +    WA ++    +  CW++       + W+  +  +    +N  LF+NI+RVL  K  + + G  + R  YRKL K+T +LV+VFG++ ++ + +      +  E    +++Y E    S QGFFV++++CF N EV  E+++ +     R T   +   P+           + +N R  + L N+  SN  +L+  T
Sbjct:   27 VGLTAQEQVLLLYDIKLQCLQNISEHNPADEVCSPGWDGLVCWPQGSPGTVTKVPCPSYVYDFNHNGFAYRQCSSNGSWVSVENRTWVNYSDCLRFLAPGIEKGKRDFFERLHIMYTVGYAVSFSSLLVAIFIIGYFRRLHCTRNYIHMHLFVSFMLRAISIFVKDRVVYANGVLQEYDTMLMDNISTVSISPLDKTQYFGCKITVLFFIYFLATNYYWILVEGLYLHSLIFMAFFSDSKYLWGFTL-IGWGVPALFVSTWAVVRATLADARCWEL---SAGNIKWIYQVPILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGVHYIVFVGMPHTFTGLGWE----LRMYCELFFNSFQGFFVSIIYCFCNGEVQAEIRKTWL----RWTLAFDWKGPV-----------VLANYRYGSVLNNSGASNQSQLTSVT 459          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Zebrafish
Match: pth2rb (parathyroid hormone 2 receptor b [Source:ZFIN;Acc:ZDB-GENE-050208-334])

HSP 1 Score: 144.05 bits (362), Expect = 2.430e-37
Identity = 116/453 (25.61%), Postives = 209/453 (46.14%), Query Frame = 1
Query:   73 SQEEQHESVYGKLQECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-----RNYTNYENCI--------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF-------------------FNLIPPSSIVWL-------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNKRAATCLTNNNGSNH*KLSVYT 1308
            + +EQ   +Y    +CL      + + + C   +D ++CWP   PG +   PCP Y+      G   RQC  +G W     R + NY +C+          K      ++ +  VGY +S   L +++ ++  F++L C RN IH+H+F +F+LRA++ F                    + I   SI  L       C++        +  ++ W+ +E L+LH+ + +    D+ Y  G  + IGW +P +    WA ++    +  CW++       + W+  +  +    +N  LF+NI+RVL  K  + + G  + R  YRKL K+T +LV+VFG++ ++ + +      +  E    +++Y E    S QGFFV++++CF N EV  E+++ +     R T   +   P+           + +N R  + L N+  SN  +L+  T
Sbjct:    2 TAQEQVLLLYDIKLQCLQNISEHNPADEVCSPGWDGLVCWPQGSPGTVTKVPCPSYVYDFNHNGFAYRQCSSNGSWVSVENRTWVNYSDCLRFLAPGIEKGKRDFFERLHIMYTVGYAVSFSSLLVAIFIIGYFRRLHCTRNYIHMHLFVSFMLRAISIFVKDRVVYANGVLQEYDTMLMDNISTVSISPLDKTQYFGCKITVLFFIYFLATNYYWILVEGLYLHSLIFMAFFSDSKYLWGFTL-IGWGVPALFVSTWAVVRATLADARCWEL---SAGNIKWIYQVPILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGVHYIVFVGMPHTFTGLGWE----LRMYCELFFNSFQGFFVSIIYCFCNGEVQAEIRKTWL----RWTLAFDWKGPV-----------VLANYRYGSVLNNSGASNQSQLTSVT 431          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Zebrafish
Match: pth3r (parathyroid hormone 3 receptor [Source:ZFIN;Acc:ZDB-GENE-991123-12])

HSP 1 Score: 141.354 bits (355), Expect = 3.210e-36
Identity = 113/397 (28.46%), Postives = 192/397 (48.36%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNLSRYMSS--SSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI-------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFF----------------NLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRN 1158
            I+++EQ   + G    C    R  S     + C  ++D ++CWP  +P ++    CP YI     RG   R C  SG W       R + NY  C        S +  V   +  +  +GY +SL  L ++V ++  FK+L C RN IH+H+F +F+ RA++ F                   +    +V  C+    +    +  +H W+ +E L+LH+ + +  + D      + I IGW IP +   +W + +    + +CW I     K   W+  +  +   ++N  LF+NIIRVL  K  + + G ++ R  YRKL K+T +L+ +FG++ ++ + L      +    ++I Q++YE    S QGFFVA ++CF N EV  EVK+ + +R+
Sbjct:   29 ITRDEQIFLLIGARSRCERTIRAQSDVVRENNCAPEWDGIICWPTGKPNQMVAVLCPEYIYDFNHRGYAYRHCDASGNWEQVSIINRTWANYTECTTYLHTNHSDQEEVFERLYLMYTIGYSISLAALLVAVSILCYFKRLHCTRNYIHIHLFTSFICRAISIFVKDAVLYAVTNDGELEDGAVEQRPMVG-CKAAVTLFLYLLATNHYWILVEGLYLHSLIFMAFLSDKNCLWALTI-IGWGIPAVFVSIWVSARVSLADTQCWDISAGNLK---WIYQVPILAAIVVNFFLFLNIIRVLASKLWETNTGKLDPRQQYRKLLKSTMVLMPLFGVHYMLFMALPY--TDVTGLLWQI-QMHYEMLFNSSQGFFVAFIYCFCNGEVQAEVKKAWLRRS 417          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Xenopus
Match: ccdc22 (coiled-coil domain containing 22 [Source:Xenbase;Acc:XB-GENE-979496])

HSP 1 Score: 143.28 bits (360), Expect = 9.450e-37
Identity = 113/403 (28.04%), Postives = 195/403 (48.39%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALT-------------------------HFFNLIPPSSIVWL--CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            I++EEQ   ++     C  L     SS+  C  ++D V+CWP   PG      CP YI     +G   R+C  +G W       R + NY  C       +K+  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA +                          F   IPP+  +    C++        +  ++ W+ +E L+LH+ + +  + D  Y  G  +  GW +P I  ++WA  +    +  CW   D     + W+  +  +   ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +       +++   ++ VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   44 ITKEEQILLLWNAKALCEKLL----SSNGLCLPEWDGVVCWPEGLPGNTVSISCPEYIQDFNHKGHAYRRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQFVGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFMAFISDKKYLWGFTL-FGWGVPAIFVLIWARERATVADTGCW---DLSAGYLKWIVQVPILAAIMVNFGLFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAFPY--TEVSGILWQ-VQMHYELLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 435          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Xenopus
Match: ccdc22 (coiled-coil domain containing 22 [Source:Xenbase;Acc:XB-GENE-979496])

HSP 1 Score: 142.124 bits (357), Expect = 2.251e-36
Identity = 114/405 (28.15%), Postives = 196/405 (48.40%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNL-SRYMSSSSD-FCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALT-------------------------HFFNLIPPSSIVWL--CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            I++EEQ   ++     C  L S   S + D  C  ++D V+CWP   PG      CP YI     +G   R+C  +G W       R + NY  C       +K+  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA +                          F   IPP+  +    C++        +  ++ W+ +E L+LH+ + +  + D  Y  G  +  GW +P I  ++WA  +    +  CW   D     + W+  +  +   ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +       +++   ++ VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   33 ITKEEQILLLWNAKALCEKLLSSSASKAHDGLCLPEWDGVVCWPEGLPGNTVSISCPEYIQDFNHKGHAYRRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQFVGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFMAFISDKKYLWGFTL-FGWGVPAIFVLIWARERATVADTGCW---DLSAGYLKWIVQVPILAAIMVNFGLFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAFPY--TEVSGILWQ-VQMHYELLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 430          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Xenopus
Match: ccdc22 (coiled-coil domain containing 22 [Source:Xenbase;Acc:XB-GENE-979496])

HSP 1 Score: 139.813 bits (351), Expect = 1.881e-35
Identity = 105/377 (27.85%), Postives = 183/377 (48.54%), Query Frame = 1
Query:  148 SSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALT-------------------------HFFNLIPPSSIVWL--CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            +   C  ++D V+CWP   PG      CP YI     +G   R+C  +G W       R + NY  C       +K+  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA +                          F   IPP+  +    C++        +  ++ W+ +E L+LH+ + +  + D  Y  G  +  GW +P I  ++WA  +    +  CW   D     + W+  +  +   ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +       +++   ++ VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   70 ADGLCLPEWDGVVCWPEGLPGNTVSISCPEYIQDFNHKGHAYRRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQFVGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFMAFISDKKYLWGFTL-FGWGVPAIFVLIWARERATVADTGCW---DLSAGYLKWIVQVPILAAIMVNFGLFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMAFPY--TEVSGILWQ-VQMHYELLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 439          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Xenopus
Match: ccdc22 (coiled-coil domain containing 22 [Source:Xenbase;Acc:XB-GENE-979496])

HSP 1 Score: 139.428 bits (350), Expect = 1.980e-35
Identity = 105/377 (27.85%), Postives = 183/377 (48.54%), Query Frame = 1
Query:  148 SSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALT-------------------------HFFNLIPPSSIVWL--CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            +   C  ++D V+CWP   PG      CP YI     +G   R+C  +G W       R + NY  C       +K+  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA +                          F   IPP+  +    C++        +  ++ W+ +E L+LH+ + +  + D  Y  G  +  GW +P I  ++WA  +    +  CW   D     + W+  +  +   ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++   +     +++   ++ VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   43 ADGLCLPEWDGVVCWPEGLPGNTVSISCPEYIQDFNHKGHAYRRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQFVGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFMAFISDKKYLWGFTL-FGWGVPAIFVLIWARERATVADTGCW---DLSAGYLKWIVQVPILAAIMVNFGLFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVF--MAFPYTEVSGILWQ-VQMHYELLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 412          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Xenopus
Match: ccdc22 (coiled-coil domain containing 22 [Source:Xenbase;Acc:XB-GENE-979496])

HSP 1 Score: 139.043 bits (349), Expect = 2.002e-35
Identity = 105/377 (27.85%), Postives = 183/377 (48.54%), Query Frame = 1
Query:  148 SSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALT-------------------------HFFNLIPPSSIVWL--CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            +   C  ++D V+CWP   PG      CP YI     +G   R+C  +G W       R + NY  C       +K+  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA +                          F   IPP+  +    C++        +  ++ W+ +E L+LH+ + +  + D  Y  G  +  GW +P I  ++WA  +    +  CW   D     + W+  +  +   ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++   +     +++   ++ VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   33 ADGLCLPEWDGVVCWPEGLPGNTVSISCPEYIQDFNHKGHAYRRCDMNGSWELVPGNNRTWANYTECAKYLFNETKEREVFDRLYLIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFISFMLRAGSIFVKDAVLYSGSALEETELISEEDLKFITEIPPADKMQFVGCKVVVTFFLYFLATNYYWILVEGLYLHSLIFMAFISDKKYLWGFTL-FGWGVPAIFVLIWARERATVADTGCW---DLSAGYLKWIVQVPILAAIMVNFGLFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVF--MAFPYTEVSGILWQ-VQMHYELLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 402          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Mouse
Match: Pth1r (parathyroid hormone 1 receptor [Source:MGI Symbol;Acc:MGI:97801])

HSP 1 Score: 144.05 bits (362), Expect = 7.435e-37
Identity = 107/376 (28.46%), Postives = 185/376 (49.20%), Query Frame = 1
Query:  160 CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF---------FNLIPPSSIVWL---------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA + F         F L     +                        CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  I  GW +P +   VW  ++    N  CW +    HK+  W+  +  + + ++N  LFINIIRVL  K  + + G  + R  YRKL ++T +LV +FG++  +   + L   +++   ++I Q++YE    S QGFFVA+++CF N EV  E+++ + +
Sbjct:  108 CLPEWDNIVCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTI-FGWGLPAVFVAVWVGVRATLANTGCWDL-SSGHKK--WIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVF--MALPYTEVSGTLWQI-QMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSWSR 476          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Mouse
Match: Pth1r (parathyroid hormone 1 receptor [Source:MGI Symbol;Acc:MGI:97801])

HSP 1 Score: 144.05 bits (362), Expect = 7.435e-37
Identity = 107/376 (28.46%), Postives = 185/376 (49.20%), Query Frame = 1
Query:  160 CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF---------FNLIPPSSIVWL---------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA + F         F L     +                        CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  I  GW +P +   VW  ++    N  CW +    HK+  W+  +  + + ++N  LFINIIRVL  K  + + G  + R  YRKL ++T +LV +FG++  +   + L   +++   ++I Q++YE    S QGFFVA+++CF N EV  E+++ + +
Sbjct:  108 CLPEWDNIVCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTI-FGWGLPAVFVAVWVGVRATLANTGCWDL-SSGHKK--WIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVF--MALPYTEVSGTLWQI-QMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSWSR 476          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Mouse
Match: Pth1r (parathyroid hormone 1 receptor [Source:MGI Symbol;Acc:MGI:97801])

HSP 1 Score: 144.05 bits (362), Expect = 7.435e-37
Identity = 107/376 (28.46%), Postives = 185/376 (49.20%), Query Frame = 1
Query:  160 CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF---------FNLIPPSSIVWL---------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA + F         F L     +                        CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  I  GW +P +   VW  ++    N  CW +    HK+  W+  +  + + ++N  LFINIIRVL  K  + + G  + R  YRKL ++T +LV +FG++  +   + L   +++   ++I Q++YE    S QGFFVA+++CF N EV  E+++ + +
Sbjct:  108 CLPEWDNIVCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWEVVPGHNRTWANYSECLKFMTNETREREVFDRLGMIYTVGYSMSLASLTVAVLILAYFRRLHCTRNYIHMHMFLSFMLRAASIFVKDAVLYSGFTLDEAERLTEEELHIIAQVPPPPAAAAVGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTI-FGWGLPAVFVAVWVGVRATLANTGCWDL-SSGHKK--WIIQVPILASVVLNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLRSTLVLVPLFGVHYTVF--MALPYTEVSGTLWQI-QMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIRKSWSR 476          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Mouse
Match: Pth2r (parathyroid hormone 2 receptor [Source:MGI Symbol;Acc:MGI:2180917])

HSP 1 Score: 133.265 bits (334), Expect = 2.819e-33
Identity = 114/408 (27.94%), Postives = 195/408 (47.79%), Query Frame = 1
Query:   67 TISQEEQHESVYGKLQEC-LNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCISKKLIVIA------SMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFF------------------------NLIPPSSI----VWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMK--ATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRN 1158
            TI+ EEQ   V     +C LN++  +      C  ++D ++CWP    G+++  PCP Y+     +G   R C  +G W       + + NY +C  +  I I       S+  L  VGY +S   L ++++++  F++L C RN IHLH+F +F+LRA++ F                         N I   S+       C++   +    +  ++ W+ +E L+LHN + +    DT Y  G +ISIGW  P +  + WA  +    +  CW++         W+     +    +N  LF+N +RVL  K   T+     +  +YRKL K+T +LV+VFG++ ++    V      +   +EI +++ E    S QGFFV++++C+ N EV  EVK+ + + N
Sbjct:   31 TITIEEQIVLVMKAKMQCELNITAQLQEGEGNCFPEWDGIICWPRGTVGKMSAVPCPPYVYDFNHKGVAFRHCTPNGTWDSIHGSNKTWANYSDCFLQPDINIGKQEFFESLYILYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHLHLFVSFMLRAMSIFVKDRVAQAHLGVEALQSLVMQGDLQNFIGGPSVDKSQYVGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVSFFSDTKYLWG-FISIGWGFPAVFVVAWAVARATLADTRCWELSAGDR----WIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDMRKQYRKLAKSTLVLVLVFGVHYIV---FVCQPHSFSGLWWEI-RMHCELFFNSFQGFFVSIVYCYCNGEVQAEVKKMWTRWN 429          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Mouse
Match: Sctr (secretin receptor [Source:MGI Symbol;Acc:MGI:2441720])

HSP 1 Score: 126.716 bits (317), Expect = 2.106e-31
Identity = 101/353 (28.61%), Postives = 174/353 (49.29%), Query Frame = 1
Query:  160 CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIR-GKTTRQCMESGYWRNYTNYENCISKKLIVIASMNHLGH-----------VGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFN---LIPPSSIVWL------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMK-ATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            C   +D + CWP +   +    PCP ++     R G   R C + G+   +   +  ++  + +  S N   H           VGY  SL  L +++ ++  F++L C RN IH+H+F +F+LRAL++F     L P   + +       C+L        I A++ W+ +E L+LH  L +    +    L  ++  GW  P I   +WA  ++   +  CW I  + +  ++W+     IL+ +IN   FINI+R+L  K  T  + G   + Y++L K+T +L+ +FGI+ ++           + E    VQL++E  + S QG  VA+L+CF+N EV  EV++ +RQ
Sbjct:   80 CERFWDNMSCWPSSALAQTVEVPCPKFLRMFSGRNGSLFRNCTKDGWSETFPRPD--LACGVNMNGSFNERRHAYLLKLKVMYTVGYSSSLAMLLVALSILCSFRRLHCTRNYIHMHLFVSFILRALSNFIKDAVLFPADDVTYCDAHRAGCKLVMIFFQYCIMANYAWLLVEGLYLHTLLAISFFSERK-CLQAFVLFGWGSPAIFVALWAVTRHFLEDFGCWDI--NSNASIWWVIRGPVILSIVINFIFFINILRILMRKLRTQETRGNETHHYKRLAKSTLLLIPLFGIHYIVF--------AFSPEGAMEVQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWRQ 419          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. UniProt/SwissProt
Match: sp|P25107|PTH1R_DIDVI (Parathyroid hormone/parathyroid hormone-related peptide receptor OS=Didelphis virginiana OX=9267 GN=PTH1R PE=1 SV=2)

HSP 1 Score: 164.851 bits (416), Expect = 1.473e-43
Identity = 116/403 (28.78%), Postives = 200/403 (49.63%), Query Frame = 1
Query:   76 QEEQHESVYGKLQECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF-------------------------FNLIPPSSIVWL--CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILI--PLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            +E+  E +Y + +E   +S        FC  ++D ++CWP   PG++   PCP YI     +G+  R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F                         F   PP+       CR+   +    +T ++ W+ +E L+LH+ + +    +  Y  G  +  GW +P +   VW T++    N ECW +     K   W+  +  +   ++N  LFINIIRVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +  P   +S  +       VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   77 KEKPAEKLYSQAEESREVSDRSRLQDGFCLPEWDNIVCWPAGVPGKVVAVPCPDYIYDFNHKGRAYRRCDSNGSWELVPGNNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSISLGSLTVAVLILGYFRRLHCTRNYIHMHLFVSFMLRAVSIFIKDAVLYSGVSTDEIERITEEELRAFTEPPPADKAGFVGCRVAVTVFLYFLTTNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTL-FGWGLPAVFVAVWVTVRATLANTECWDLSSGNKK---WIIQVPILAAIVVNFILFINIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGILWQ-----VQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 470          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. UniProt/SwissProt
Match: sp|P50133|PTH1R_PIG (Parathyroid hormone/parathyroid hormone-related peptide receptor OS=Sus scrofa OX=9823 GN=PTH1R PE=1 SV=1)

HSP 1 Score: 149.058 bits (375), Expect = 8.018e-38
Identity = 111/404 (27.48%), Postives = 192/404 (47.52%), Query Frame = 1
Query:   73 SQEEQHESVYGKLQECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFN----------------------------LIPPSSIVWL-CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            S + + E   GKL                C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F                              L P ++  ++ CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  +  GW +P I   VW +++    N  CW +     K   W+  +  + + ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +          S +   VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   75 SGKPRKEKASGKLYPESGEDTGSRHQGRPCLPEWDHILCWPLGAPGEVVAMPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPLPPVAATSYVGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTV-FGWGLPAIFVAVWVSVRATLANTGCWDLSSGNKK---WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEV---SGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 471          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. UniProt/SwissProt
Match: sp|Q9TU31|PTH1R_CANLF (Parathyroid hormone/parathyroid hormone-related peptide receptor OS=Canis lupus familiaris OX=9615 GN=PTH1R PE=1 SV=1)

HSP 1 Score: 145.591 bits (366), Expect = 1.352e-36
Identity = 111/411 (27.01%), Postives = 193/411 (46.96%), Query Frame = 1
Query:   64 VTISQEEQHESVYGKLQECLNLSRYMSSSSDF----CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWL-----------------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
             + S + + E   GKL       + + + S      C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F       S   L                             CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  +  GW +P +   VW +++    N  CW +     K   W+  +  + + ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +          S +   VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   72 ASTSGKPKKEKASGKLYPESEEDKEVPTGSRHRGRPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPTAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTV-FGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK---WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEV---SGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 475          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. UniProt/SwissProt
Match: sp|Q1LZF7|PTH1R_BOVIN (Parathyroid hormone/parathyroid hormone-related peptide receptor OS=Bos taurus OX=9913 GN=PTH1R PE=2 SV=1)

HSP 1 Score: 145.206 bits (365), Expect = 1.481e-36
Identity = 112/411 (27.25%), Postives = 193/411 (46.96%), Query Frame = 1
Query:   64 VTISQEEQHESVYGKLQECLNLSRYMSSSSDF----CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWL-----------------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
             + S + + E   GKL       + + + S      C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F       S   L                             CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  +  GW +P I   VW +++    N  CW +     K   W+  +  + + ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +          S +   VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   72 ASTSGKPKKEKPSGKLHPESEEDKEVPTGSRPRGRPCLPEWDHILCWPLGAPGEVVAMPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGTALDEAERLTEEELRAIAQAPPPPAAAAGYVGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTV-FGWGLPAIFVAVWVSVRATLANTGCWDLSSGNKK---WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTE---VSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 475          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. UniProt/SwissProt
Match: sp|Q03431|PTH1R_HUMAN (Parathyroid hormone/parathyroid hormone-related peptide receptor OS=Homo sapiens OX=9606 GN=PTH1R PE=1 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 2.099e-36
Identity = 113/415 (27.23%), Postives = 194/415 (46.75%), Query Frame = 1
Query:   64 VTISQEEQHESVYGKL-------QECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWL------------------------------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
             + S + + +   GKL       +E    SRY       C  ++D ++CWP   PGE+   PCP YI     +G   R+C  +G W       R + NY  C+      +++  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F       S   L                              CR+        +  ++ W+ +E L+LH+ + +    +  Y  G  +  GW +P +   VW +++    N  CW +     K   W+  +  + + ++N  LFINI+RVL  K  + + G  + R  YRKL K+T +L+ +FG++ ++ +          S +   VQ++YE    S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   72 ASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRP---CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTV-FGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK---WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTE---VSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSR 476          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. TrEMBL
Match: A0A504YH66 (Parathyroid hormone/parathyroid hormone peptide receptor OS=Fasciola gigantica OX=46835 GN=FGIG_02463 PE=3 SV=1)

HSP 1 Score: 218.394 bits (555), Expect = 1.722e-61
Identity = 138/389 (35.48%), Postives = 221/389 (56.81%), Query Frame = 1
Query:   82 EQHESVYGKLQ-EC-----LNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQC-----------MESGYWR-NYTNYENCIS-KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLK-YLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLL---SEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLN 1179
            E+ +++  +LQ EC     +++     + S  C  +FD +MCWP T   E    PCP YI G+ + GK  R C              G W  + TNY  C+   + + +  +N +GH+GY  S++ L +++ +M RF++L C RN +H+++F A +LR + HF  ++   +  WLC+    ++  +I A+++WVF+EALFLHNT+L+H+M D+  +L +YISIGW+ P ++  VW  L+ Y+    ECW +          L ++YP +  L+N   F++I+RV+F+K   +      NR R + ++T +LVI+FGIY +I IPL L+         +  E  QLYY   M S QGF V+LL CF+N EV  E+KR YR+ + R   ++
Sbjct:   49 EETQAILKRLQVECAQNRSMDIHDARFAGSPHCFAEFDTIMCWPTTPANETVHLPCPSYIGGVSVTGKAWRSCEYIPPGTHNYSSRIGQWLFDATNYSECVEIDRDLHLEFLNIIGHIGYTTSVLSLTVAIGIMLRFRRLRCTRNRVHINLFSAIILRGVCHFLQIVNFET-AWLCKAVTVLNTYTIEATYSWVFVEALFLHNTVLVHVMNDSSISLAVYISIGWVTPLLVTFVWVLLRIYVTPGPECWILDVGAVSSSRLLLIIYPSVMILLNGAFFVSILRVIFVKMQSQPTSEA-NRLRTILRSTLVLVIIFGIYHMIFIPLDLMHSPQSTFQPKIMEFAQLYYRQVMESFQGFLVSLLLCFLNKEVTSEIKRIYRRTHPRSMSID 435          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. TrEMBL
Match: A0A4E0RXW4 (Parathyroid hormone/parathyroid hormone peptide receptor OS=Fasciola hepatica OX=6192 GN=D915_000825 PE=3 SV=1)

HSP 1 Score: 217.238 bits (552), Expect = 3.706e-61
Identity = 137/389 (35.22%), Postives = 221/389 (56.81%), Query Frame = 1
Query:   82 EQHESVYGKLQ-EC-----LNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCM-----------ESGYWR-NYTNYENCIS-KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLK-YLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLL---SEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLN 1179
            E+ +++  +LQ EC     +++     + S  C  +FD +MCWP T   E    PCP YI G+ + GK  R C              G W  + TNY  C+   + + +  +N +GH+GY  S++ L +++ +M RF++L C RN +H+++F A +LR + HF  ++   +  W+C+    ++  +I A+++WVF+EALFLHNT+L+H+M D+  +L +YISIGW+ P ++  VW  L+ Y+    ECW +          L ++YP +  L+N   F++I+RV+F+K   +      NR R + ++T +LVI+FGIY +I IPL L+         +  E  QLYY   M S QGF V+LL CF+N EV  E+KR YR+ + R   ++
Sbjct:   49 EETQAILKRLQVECAQNRSMDVHDARFAGSPHCFAEFDSIMCWPTTPANETVHLPCPSYIGGVSVTGKAWRSCEYIPPGTHNYSNRIGQWLFDATNYSECVEIDRDLHLEFLNIIGHIGYTTSVLSLTVAIGIMLRFRRLRCTRNRVHINLFSAIILRGVCHFLQIVNFET-AWICKAVTVLNTYTIEATYSWVFVEALFLHNTVLVHVMNDSSISLAVYISIGWVTPLLVTFVWVLLRIYVTPGPECWILDVGAVSSSRLLLIIYPSVMILLNGAFFVSILRVIFVKMQSQPTSEA-NRLRTILRSTLVLVIIFGIYHMIFIPLDLMHSPQSTFQPKIMEFAQLYYRQVMESFQGFLVSLLLCFLNKEVTSEIKRIYRRTHPRSMSID 435          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. TrEMBL
Match: A0A0A0P3Y4 (Family B1 G-protein coupled receptor OS=Fasciola gigantica OX=46835 GN=PTHRL PE=2 SV=1)

HSP 1 Score: 213.772 bits (543), Expect = 7.612e-60
Identity = 136/389 (34.96%), Postives = 220/389 (56.56%), Query Frame = 1
Query:   82 EQHESVYGKLQ-EC-----LNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQC-----------MESGYWR-NYTNYENCIS-KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLK-YLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLL---SEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLN 1179
            E+ +++  ++Q EC     +++     + S  C   FD +MCWP T   E    PCP YI G+ + GK  R C              G W  + TNY  C+   + + +  +N +GH+GY  S++ L +++ +M RF++L C RN +H+++F A +LR + HF  ++   +  WLC+    ++  +I A+++WVF+EALFLHNT+L+H+M ++  +L +YISIGW+ P ++  VW  L+ Y+    ECW +          L ++YP +  L+N   F++I+RV+F+K   +      NR R + ++T +LVI+FGIY +I IPL L+         +  E  QLYY   M S QGF V+LL CF+N EV  E+KR YR+ + R   ++
Sbjct:   49 EETQAILKRVQVECAQNRSMDIHDARFAGSPHCFAKFDTIMCWPTTPANETVHLPCPSYIGGVSVTGKAWRSCEYIPPGTHNYSSRIGQWLFDATNYSECVEIDRDLHLEFLNIIGHIGYTTSVLSLTVAIGIMLRFRRLRCTRNRVHINLFSAIILRGVCHFLQIVNFET-AWLCKAVTVLNTYTIEATYSWVFVEALFLHNTVLVHVMNESSISLAVYISIGWVTPLLVTFVWVLLRIYVTPGPECWILDVGAVSSSRLLLIIYPSVMILLNGAFFVSILRVIFVKMQSQPTSEA-NRLRTILRSTLVLVIIFGIYHMIFIPLDLMHSPQSTFQPKIMEFAQLYYRQVMESFQGFLVSLLLCFLNKEVTSEIKRIYRRTHPRSMSID 435          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. TrEMBL
Match: A0A4S2LH17 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007228 PE=3 SV=1)

HSP 1 Score: 208.764 bits (530), Expect = 2.783e-57
Identity = 141/398 (35.43%), Postives = 219/398 (55.03%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECL-NLS---RYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCM-----------ESGYWR-NYTNYENCISKKLIVIASMNH------LGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKY-LYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQ---INSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEH 1185
            IS+EE   ++     ECL N S   + M  + DFC  +F   +CWP T        PCP Y+ G+R  G+ +R+C             +G+W+ +   + +C++   +V +S  H      +G  GY +S + L  ++ +M RF++L C RNTIH+++F A LLR L HF      ++I W CRL   +  L++TA+H+WVF+EAL+LHNT+L+H+   T  ++  YI  GW+ P IL  VW  L+  +     CW + + PH     L  L P++  L NL   IN+ R++ +K   +++G   +R + L K+ +IL+++FGIY ++ +PL L+  Q      E  EI++LY  H M   QGF  AL+ CF+N EV  E+KR Y Q   R   L+ H
Sbjct:  102 ISEEESLRAIEVTRAECLRNRSIDEQAMRGNQDFCLAEFASAVCWPTTPGNHTVTMPCPHYVPGVRKHGQVSRRCFWSHNVDEETNGSAGHWQFSDVEFRDCLA---VVESSSGHVKILIHIGTAGYAISTLSLVFAITIMVRFRRLRCTRNTIHVNLFSAILLRCLVHFMQKTLDTNIQWFCRLLTTLTTLTVTATHSWVFVEALYLHNTVLIHIFHSTVSSIVGYIITGWVTPIILTAVWVVLRLTITTGTTCWILDNTPHSPSRLLLSLSPVVMLLFNLAFSINVFRLVLVKMKSQTSG-ETSRVKTLLKSISILILIFGIYHLVFLPLDLMESQHAHYGIEQLEIIKLYCRHVMEGLQGFCAALILCFMNKEVTAELKRRYHQSRMRGAVLDTH 495          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. TrEMBL
Match: A0A3Q0KSN3 (Putative g-protein coupled receptor OS=Schistosoma mansoni OX=6183 PE=3 SV=1)

HSP 1 Score: 199.134 bits (505), Expect = 1.587e-54
Identity = 138/395 (34.94%), Postives = 224/395 (56.71%), Query Frame = 1
Query:   64 VTISQEEQHESVYGKLQECLNLSRYMS------SSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQC-----------MESGYWR-NYTNYENCISKKLIVIASMNHLGHV------GYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLK-YLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSES-----FEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRN 1158
            +TI   ++ E +  K++    L+R +       S +++C  +FD V CWPPT+ G IA  PCP ++ G++I G   R C            ++  W+ + +NY +C+  + I+     HL  +      GY +S++ L I+  ++ RF++L C RN +HL++F A LLR + HF         V +C++F  +   +I A+++WV +EAL+LHN++L+H+M ++  +  +Y SIGW +P ++  VW  L+ ++    +CW +          L ++YP +  L NL  F+N++RV+F K   +       R R L K+T++LVIVFG+Y + LIPL L+  QIN+        EI++LYYE  M + QG FVA+L CFIN EVI E KR YR++ 
Sbjct:   10 ITILSPKEAEVLREKVKNECELNRTLDEKSQSYSQTEYCLTEFDSVSCWPPTKGGTIAKIPCPSHVPGVKITGTVYRPCNLTIETQDLNGRKTIVWKFDRSNYSDCVHHEDIM---ATHLPIIQTSVFYGYAISMVLLLIATGILLRFRRLRCTRNNLHLNLFSAILLRCVLHFIKHAADGQGV-ICKIFTTLHVFTIEATYSWVLMEALYLHNSVLVHVMHESRTSFILYASIGWSLPILVITVWVLLRIFVTTGDQCWDLDIGSGSPSRILLIVYPAIIMLFNLAFFVNLLRVIFNKTQSQPMSDAK-RLRTLLKSTSVLVIVFGLYHLFLIPLNLM--QINTHINGPGLLEIIKLYYEQIMEAFQGSFVAILLCFINKEVISEFKRVYRRKQ 397          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Cavefish
Match: pth2ra (parathyroid hormone 2 receptor [Source:NCBI gene;Acc:103034973])

HSP 1 Score: 156.377 bits (394), Expect = 1.341e-41
Identity = 109/405 (26.91%), Postives = 200/405 (49.38%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCIS------KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFF--------------------------NLIPPSSIVWL-CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRN 1158
            I+ EEQ + +     +CL        + D CP ++D ++CWP   PG +A  PCP YI      G   R+C  +  W       + + NY  CI       ++ +    ++ +  VGY +S   L ++++++  F++L C RN IH+H+F +F+LRA++ F                           ++ P  +  ++ C++   +    +  ++ W+ +E L+LH+ + +  + DT Y  G  + IGW +P +    WA ++    +  CW++       + W+  +  +    +N  LF+NI+RVL  K  + + G  + R  YRKL K+T +LV+VFG++ ++ + +    E +  E    V++Y E    S QGFFV++++CF N EV  E+K+ + + N
Sbjct:   29 ITAEEQVQMLLDARLQCLQTVSSHDLAVDECPAEWDGLICWPRGYPGTLAKVPCPRYIYDFNHAGHAYRRCDSNSSWLLGESLNKTWANYTECIKSPGPNRERQVFFERLHIMYTVGYAVSFGSLLVAILIIGYFRRLHCTRNYIHMHLFVSFMLRAVSIFVKDRVVHTSAGLQEFDAVLMNNFTNAVDVAPVDTSQYMGCKVTVLLFIYFLATNYYWILVEGLYLHSLIFMAFLSDTKYLWGFTL-IGWGVPAVFVATWAIVRATVADSRCWEL---SAGNIKWIYQVPILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGVHYIVFVGMPHTIEGLGWE----VRMYCELFFNSFQGFFVSIIYCFCNGEVQTEIKKTWTRWN 425          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Cavefish
Match: pth2ra (parathyroid hormone 2 receptor [Source:NCBI gene;Acc:103034973])

HSP 1 Score: 155.992 bits (393), Expect = 1.564e-41
Identity = 109/405 (26.91%), Postives = 200/405 (49.38%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCIS------KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFF--------------------------NLIPPSSIVWL-CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRN 1158
            I+ EEQ + +     +CL        + D CP ++D ++CWP   PG +A  PCP YI      G   R+C  +  W       + + NY  CI       ++ +    ++ +  VGY +S   L ++++++  F++L C RN IH+H+F +F+LRA++ F                           ++ P  +  ++ C++   +    +  ++ W+ +E L+LH+ + +  + DT Y  G  + IGW +P +    WA ++    +  CW++       + W+  +  +    +N  LF+NI+RVL  K  + + G  + R  YRKL K+T +LV+VFG++ ++ + +    E +  E    V++Y E    S QGFFV++++CF N EV  E+K+ + + N
Sbjct:   19 ITAEEQVQMLLDARLQCLQTVSSHDLAVDECPAEWDGLICWPRGYPGTLAKVPCPRYIYDFNHAGHAYRRCDSNSSWLLGESLNKTWANYTECIKSPGPNRERQVFFERLHIMYTVGYAVSFGSLLVAILIIGYFRRLHCTRNYIHMHLFVSFMLRAVSIFVKDRVVHTSAGLQEFDAVLMNNFTNAVDVAPVDTSQYMGCKVTVLLFIYFLATNYYWILVEGLYLHSLIFMAFLSDTKYLWGFTL-IGWGVPAVFVATWAIVRATVADSRCWEL---SAGNIKWIYQVPILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGVHYIVFVGMPHTIEGLGWE----VRMYCELFFNSFQGFFVSIIYCFCNGEVQTEIKKTWTRWN 415          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Cavefish
Match: pth3r (parathyroid hormone/parathyroid hormone-related peptide receptor-like [Source:NCBI gene;Acc:103044101])

HSP 1 Score: 150.599 bits (379), Expect = 1.464e-39
Identity = 117/432 (27.08%), Postives = 209/432 (48.38%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNLSRYMSSS--SDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCIS--------KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF----------------FNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNKRAATC 1260
            I+++EQ   + G   +C    R    S   + C  ++D ++CWP  +PG++    CP YI     +G   R C  SG W       R ++NY  C +        ++  V   ++ +   GY +SL  L ++V ++  FK+L C RN IH H+F +F+ RA++ F                + ++ P   +  C+L        +  +H W+ +E L+LH+ + +  + D  Y   + I IGW +P +   +W +++    + +CW I     K   W+  +  +   ++N  LF+NIIRVL  K  + + G ++ R  YRKL K+T +L+ +FG++ ++   + L   ++    ++ VQ++YE    S QGFFVA ++CF N EV  EVK+ + +R              S++   ++   I S+    +C
Sbjct:   29 ITRDEQIFLLIGARTKCERSIRSQQGSIRENDCVPEWDGIICWPRGKPGQLVAVLCPEYIYDFNHQGNAYRNCDVSGNWEQVPIINRTWSNYTECTTYLHSNHAGQQEAVFRRLHLMYTTGYSISLASLLVAVFILCFFKRLHCTRNYIHTHLFTSFICRAVSIFVKDAVLYTFAEEVETDYVVVDPRPPMVGCKLAVTFFLYFLATNHYWILVEGLYLHSLIFMAFLSDKNYLWALTI-IGWGVPALFVSIWVSVRASLADTQCWDISAGNLK---WIYQVPILAAIVVNFFLFLNIIRVLASKLWETNTGKLDPRQQYRKLLKSTLVLMPLFGVHYMVF--MALPYTEVTGLLWQ-VQMHYEMFFNSLQGFFVAFIYCFCNGEVQAEVKKAWLRR--------------SLVLDLKQKARITSSAGGGSC 439          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Cavefish
Match: pth3r (parathyroid hormone/parathyroid hormone-related peptide receptor-like [Source:NCBI gene;Acc:103044101])

HSP 1 Score: 148.288 bits (373), Expect = 1.257e-38
Identity = 118/434 (27.19%), Postives = 210/434 (48.39%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNLSRYMSSS--SDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCIS---------KKLIVIASMNHLGHV-GYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF----------------FNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNKRAATC 1260
            I+++EQ   + G   +C    R    S   + C  ++D ++CWP  +PG++    CP YI     +G   R C  SG W       R ++NY  C +         +++  +    HL +  GY +SL  L ++V ++  FK+L C RN IH H+F +F+ RA++ F                + ++ P   +  C+L        +  +H W+ +E L+LH+ + +  + D  Y   + I IGW +P +   +W +++    + +CW I     K   W+  +  +   ++N  LF+NIIRVL  K  + + G ++ R  YRKL K+T +L+ +FG++ ++   + L   ++    ++ VQ++YE    S QGFFVA ++CF N EV  EVK+ + +R              S++   ++   I S+    +C
Sbjct:   28 ITRDEQIFLLIGARTKCERSIRSQQGSIRENDCVPEWDGIICWPRGKPGQLVAVLCPEYIYDFNHQGNAYRNCDVSGNWEQVPIINRTWSNYTECTTYLHSNHAGQQEVKAVFRRLHLMYTTGYSISLASLLVAVFILCFFKRLHCTRNYIHTHLFTSFICRAVSIFVKDAVLYTFAEEVETDYVVVDPRPPMVGCKLAVTFFLYFLATNHYWILVEGLYLHSLIFMAFLSDKNYLWALTI-IGWGVPALFVSIWVSVRASLADTQCWDISAGNLK---WIYQVPILAAIVVNFFLFLNIIRVLASKLWETNTGKLDPRQQYRKLLKSTLVLMPLFGVHYMVF--MALPYTEVTGLLWQ-VQMHYEMFFNSLQGFFVAFIYCFCNGEVQAEVKKAWLRR--------------SLVLDLKQKARITSSAGGGSC 440          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Cavefish
Match: pth1r (parathyroid hormone 1 receptor [Source:ZFIN;Acc:ZDB-GENE-991123-8])

HSP 1 Score: 147.517 bits (371), Expect = 1.543e-38
Identity = 110/411 (26.76%), Postives = 204/411 (49.64%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNLSRYMSSS----SDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCI--------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLI-------------------------PPSSIVWL--CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRN 1158
            +++EEQ   ++   ++C    R + S       FC  ++D ++CWP   PG      CP YI     +G   R+C  +G W       + + NY  C         +++  V   +  +  +GY +SL  L ++V+++  F++L C RN IH+H+F +F+LRA++ F   +                         PP++      C++   +    +  ++ W+ +E L+LH+ + +    D  Y  G  + IGW +P +   VWA+++    + ECW   D     + W+  +  +   ++N  LF+NIIRVL  K  + + G  ++R  YRKL K+T +L+ +FG++ ++ + +     +++   ++I Q++YE    S QGFFVA+++CF N EV  E+K+ + +R 
Sbjct:   35 LTKEEQIYLLFNAKRKC---ERAIKSRHRLPEGFCMPEWDGILCWPEGAPGRTVSTACPEYIYDFNHKGHAYRRCDLNGSWELATSNNKTWANYSECAKFLHYNHQNQEREVFDRLYLIYTIGYSISLGSLMVAVVILGYFRRLHCTRNYIHMHLFVSFMLRAISIFVKDVVLYSGAVLEETERVTVEDLKSITEAPPANKTQFVGCKIAVTLFLYFLATNYYWILVEGLYLHSLIFMTFFSDRKYLWGFTL-IGWGVPAMFVTVWASVRATLADTECW---DLSAGNLKWIVQIPILTAIVVNFLLFLNIIRVLATKLRESNAGRCDSRQQYRKLLKSTLVLMPLFGVHYIVFMAMPY--TEVSGIPWQI-QMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRRT 435          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Sea Lamprey
Match: pth1r (parathyroid hormone 1 receptor [Source:ZFIN;Acc:ZDB-GENE-991123-8])

HSP 1 Score: 148.288 bits (373), Expect = 3.285e-40
Identity = 119/403 (29.53%), Postives = 190/403 (47.15%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNL--SRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW------RNYTNYENCI--------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFF----------------NLIPPSS---IVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMK--ATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPL-----VLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            I++EEQ   +      C     S   SS+   C  ++D ++CWP   PG +  + CP YI      G   R+C  +G W      R + NY  C         +K+   I  ++ L  +GY +SL  L I++ ++T F++L C RN IH+H+F +F+LRA + F                    PP+    I   CR+   +    +  S+ WV +E L+L++ + L         L  +  IGW  P +   VWA  +    N +CW +     K   W+     +    +N  LF+NI+RVL  K   T+ +      +YRKL K+T +L+ +FG++ V+   +     + L+ QI        Q+YYE T  S QGFFVA+++CF N EV  E+K+ + +
Sbjct:   16 ITKEEQMFMLTEAKTHCEKTIHSTNASSADTHCTAEWDGLICWPWGLPGSMVREKCPSYIYDFNAHGHAYRKCESNGTWKMSTANRLWANYSECTEFLNPHVQAKEKESIHRLSILYTIGYSVSLASLAIALCILTVFRRLHCTRNYIHMHLFVSFMLRAASIFVKDGVLYSDNELRLATPGPSPPAEAPHIFAGCRVVVTLFLYCLATSYFWVLVEGLYLYSLIFLTF--SASGRLWTFALIGWGFPVVFVFVWAAARATLANSQCWDLSAGWLK---WIYQAPILAAVAVNFVLFVNIVRVLATKLRETNAARQESRQQYRKLLKSTLVLMPLFGVHYVLFAAMPYTDVIGLAWQI--------QMYYEMTFNSFQGFFVAIIYCFCNGEVRGEMKKLWSR 405          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000542.1 (pep scaffold:Pmarinus_7.0:GL476735:164228:192153:1 gene:ENSPMAG00000000476.1 transcript:ENSPMAT00000000542.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 114.005 bits (284), Expect = 5.741e-28
Identity = 103/367 (28.07%), Postives = 182/367 (49.59%), Query Frame = 1
Query:  142 SSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENC---ISKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNL--------IPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLF--MKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFE-IVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYY----RQRNDRR 1167
            S S   C   +D  +CW  T  G++A+Q CP Y     ++ K T+ C   G W       R ++NY  C    + KL +  ++ +L   G+G+S++ L +S+ +   FK LSC R T+H ++F +++L ++     L        +  S  VW C++        +  ++ W+  E ++LH  +++ +  +  +    Y+ +GW  P +  ++ A  + +Y +  CW I    H  + ++     +   L+NL   +NI+RVL   +K T R+     + Y K  +AT ILV + GI   +L+P     E+   E ++ I+Q++  H +   QGF VA +FCF N EV   +KRY+    R  ++RR
Sbjct:   35 SVSRKHCNRTWDGWLCWGDTMAGDVAVQHCPDYFPDFDLQEKVTKICNTDGQWFRHPDSNRTWSNYTLCNAFTADKLKMAVNLFYLAVTGHGVSILVLLVSLTIFFYFKSLSCQRITLHKNLFMSYILNSIITIIQLTAVANNQELVASKPVW-CKVLQFFHQYMMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLFWYYL-LGWGFPIVPALMHAVARTIYYDDNCW-ISSATH--LLYIIHGPVVAALLVNLFFLLNIVRVLVTKLKVTHRAE---TSMYMKAVRATLILVPLLGI-QFVLVPWK--PERFVGEIYDYIMQIFPTHLI---QGFLVATIFCFCNGEVQAALKRYWILYLRMGHERR 387          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004899.1 (pep scaffold:Pmarinus_7.0:GL476767:721819:758871:-1 gene:ENSPMAG00000004402.1 transcript:ENSPMAT00000004899.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 102.834 bits (255), Expect = 3.719e-24
Identity = 100/344 (29.07%), Postives = 161/344 (46.80%), Query Frame = 1
Query:  187 CWPPTRPGEIAIQPCPLYINGLRIRGKTT--RQCMESGYWRNYTNYENCISKKLIVIASMNHLGHVGYGLSLIFLG--ISVIVM-TRF------KKLSCPRNTIHLHVFYAFLLR----ALTHFFNLIPPSSIVWLCRLFAAI-DYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEV-KRYYRQRNDRR 1167
            CWP +  G     PCP   NG+R     +  R+C+ +G W   +NY  C   K I+ A   +  H    L + +LG  IS+  + T F      + + C RN IH H+   F+LR     L    +L         CR+   + +Y  +T +  W+F+E  +LH  +++    D      I++ IGW IP  + IVWA +K  Y +++CW       K + ++     IL  L+N     NI+R+L  K    +        RK  KAT +L+ + GI    ++  V   E   S   +++ +Y    + S QGFFV++ +CF+N EV   + KR+ R  ++ R
Sbjct:   52 CWPESEAGRTVATPCPERFNGVRYDSSKSVIRECLANGTWAQRSNYSLC---KPIIDAKKPNSQHYKIALIVNYLGHCISLAALITAFGFFWWLRSIRCLRNAIHWHLVTTFILRNAAWLLLQIIDLSTQERNEPWCRVVITVFNYFQVT-NFFWMFVEGCYLHTAIVMTYSTD-KLRKSIFVCIGWCIPAPIIIVWAMVKLFYEDEKCW-FGKTEGKYIDYIYQGPIILVLLVNFIFLFNIVRILMTKLRASTTSETIQYSRKAVKATLVLLPLLGI--TYMLFFVNPGEDPVS---QVIFIYVNSFLMSFQGFFVSVFYCFLNGEVRSALRKRWNRWMDNHR 384          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009958.1 (pep scaffold:Pmarinus_7.0:GL477206:37870:64312:-1 gene:ENSPMAG00000008983.1 transcript:ENSPMAT00000009958.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.5893 bits (231), Expect = 3.872e-21
Identity = 105/361 (29.09%), Postives = 174/361 (48.20%), Query Frame = 1
Query:  124 NLSRYMSSSSDFCPYDFDKV-MCWPPTRPGEIAIQPCPLYINGLRIRGKTT--RQCMESGYWRNYTNYENCI--------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFF-NLIPPSSIV----WLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMK--ATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEV-KRYYR 1149
            +LS  +  +  FC    D++  CWP +    + I+PCP   NG++     +  R+CM    W   +NY  C         S+   V   +N+LGH    +SL+ L  +  +    + + C RN IH ++   F+LR  T F   LI  S+      W C +    +Y  +T +  W+F+E  +LH  +++    D      I+I IGW+IP  + I+WA +K  + +++CW     P K + ++     IL  LIN     NI+ +L  K  A+  S  +   +YRK  KAT +L+ + GI       ++        E  +++ LY    + S QGFFV++ +CF+N EV   + KR++R
Sbjct:    1 HLSPTVLHAGPFCNATRDEIGTCWPSSEASRVVIRPCPDRFNGVQYDTSKSVYRECMADATWARRSNYSLCEAIILSKRNSQHYKVALVVNYLGHC---VSLLALMTAFTIFWCLRSIRCLRNAIHWNLMTTFILRNATWFLLQLIDLSTQERNEPWCCIIITIFNYFQVT-NFFWMFVEGCYLHTAIVMTYSTD-KLRKWIFICIGWVIPAPIIIIWAMVKLHFEDEKCW-FGKTPGKYIDYIYQGPIILVLLINFIFLFNIVTILMTKLRASTTSETI---QYRKAVKATLVLLPLLGI-----TYMLFFVNPGEDEISQVIFLYVNSFLMSFQGFFVSVFYCFLNGEVRSAIRKRWHR 347          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004243.1 (pep scaffold:Pmarinus_7.0:GL484465:15708:23345:-1 gene:ENSPMAG00000003877.1 transcript:ENSPMAT00000004243.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.1149 bits (209), Expect = 1.646e-18
Identity = 69/257 (26.85%), Postives = 114/257 (44.36%), Query Frame = 1
Query:  148 SSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGL-RIRGKTT-RQCMESGYWRNYTNY-------------ENCIS---KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLR---------ALTHFFNLIPPSSIVWL----------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWL 807
            S  +C   FD   CWP + P      PCP Y+  + ++ G    R C   G W    N              EN IS   K++ ++ ++  +   GY +SL  L +++ ++  F++L C RN IH+++F +F+LR         ALTH +   P ++  WL          CR         I A++ W+ +E  +LH  L + +       +  Y+ +GW  P +  I W   K +Y N+ CW I  +    ++WL
Sbjct:   29 SGVYCNRTFDHYACWPDSLPDTKVAIPCPSYLPWIDKVEGGYVYRYCTRDGTWLTQDNVTAAWRDHSECLDDENNISTEGKEMYLLHALRLVYTTGYSVSLASLVVAMGILIMFRRLHCTRNYIHMNLFASFILRAISVLLKDAALTHNYTKRPQNASDWLGYFGYEGYTGCRATHVFMQYCIGANYFWLLVEGSYLHTLLTMCVFTKKK-LIAFYVLLGWGTPIMFIIPWMVSKLIYENQGCWGI--NTWMGIWWL 282          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Medaka
Match: pth2ra (parathyroid hormone 2 receptor [Source:NCBI gene;Acc:101167084])

HSP 1 Score: 154.836 bits (390), Expect = 5.154e-41
Identity = 115/409 (28.12%), Postives = 206/409 (50.37%), Query Frame = 1
Query:   70 ISQEEQHESVYG-KLQECLNLSRYMSSSSD-FCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW-------RNYTNYENCIS---------KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF-------------------FNLIPPSSIVWL-------CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRN 1158
            +S +EQ   +Y  K+Q   NLS    +++D  CP D+D ++CWP   PG++   PCP YI     +G   R+C  +G W       + +TNY  C+S          +      +  +   GY +S   L ++++++  F++L C RN IH+H+F +F+LRA++ F                    + +   SI  +       C++   +    +  ++ W+ +E L+LH+ + +    D+ Y  G +I IGW +P +   +WA ++    +  CW++       V W+  +  +    +N  LF+NI+RVL  K  + + G  + R  YRKL K+T +LV+VFGI+ +I +    +       S+E+ ++Y+E    S QGFFV++++C+ N EV  E+K+ + + N
Sbjct:   42 LSAQEQMLILYEVKIQCYQNLSSMEPTTTDEVCPPDWDGLICWPHGSPGQVTEVPCPSYIYDFNHKGHAYRKCDVNGSWVFVEQWNKTWTNYSECLSFLQPFKDEEARQDFFERLYVMYTTGYAVSFSSLLVAIMIIGYFRRLHCTRNYIHMHLFVSFMLRAVSIFVKDKVVYSSAGLQDFDSALLDNLKTVSIASVDKSHYIGCKMTVVLFIYFLATNYYWILVEGLYLHSLIFMAFRSDSKYLWG-FIFIGWGVPAVFVAIWAIVRATLADARCWEL---SAGNVKWIYQVPILTAIGLNFILFVNIVRVLATKIRETNAGRYDTRKQYRKLAKSTLVLVLVFGIHYIIFVG---MPHTFQGPSWEM-RMYFELFFNSFQGFFVSIIYCYCNGEVQTEIKKTWTRWN 442          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Medaka
Match: pth3r (parathyroid hormone/parathyroid hormone-related peptide receptor [Source:NCBI gene;Acc:101173747])

HSP 1 Score: 148.288 bits (373), Expect = 1.075e-38
Identity = 118/397 (29.72%), Postives = 202/397 (50.88%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQEC---LNLSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYWR-------NYTNYENCI--------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF------FNLIP------PSSIVWLCRLFAAIDYLS--ITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRN 1158
            I+++EQ   + G    C   +     +    D  P ++D ++CWP +R G++   PCP YI     RG+  RQC  +G W         + NY  C         S +  V   ++ +  VGY +SL  L ++V ++  FK+L C RN IH+H+F +F+ RA++ F      +++        P+   +     AA+ +    +  +H W+  E L+LH+ + + L+ D  Y L +   +GW IP +   VW + +    + +CW I     K   W+  +  +    +N  LFINIIRVL  K  + + G +N R  YRKL ++T +L+ +FG++ ++ + +     ++N   ++ VQ++YE    S QGFFVA ++CF N EV  EVK+ + +R+
Sbjct:   29 ITRDEQIYVLTGAQARCERSIQTQTAIIKEGDCVP-EWDGIICWPQSRAGQLVSVPCPEYIYDFNHRGRAYRQCDVTGNWELVTSNNHTWANYTECTRYLTSNHRSLQEKVFKRLHLMYTVGYSISLSSLLVAVSILCYFKRLHCTRNYIHIHLFTSFICRAVSIFVKDSVLYSITDDSKAEFPAERQYTAGCKAAVTFFLYFLATNHYWILAEGLYLHSLIFMALLSDKNY-LWVLTIMGWGIPAVFVSVWVSARASLADTQCWDISAGNLK---WIYQVPILAGIFVNFLLFINIIRVLASKLWETNTGKLNPRQQYRKLLRSTLVLMPLFGVHYIVFMAIPY--TEVNGLLWQ-VQMHYEMFFNSSQGFFVAFIYCFCNGEVQAEVKKAWLRRS 417          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Medaka
Match: pth1r (parathyroid hormone 1 receptor [Source:NCBI gene;Acc:101155466])

HSP 1 Score: 147.517 bits (371), Expect = 1.429e-38
Identity = 109/406 (26.85%), Postives = 201/406 (49.51%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLN-LSRYMSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYW------RNYTNYENCI--------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHF-------------------------FNLIPPSSIVWL--CRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNR--YRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQR 1155
            +++EEQ   +      C N ++      + FC  ++D ++CWP   PG++    CP YI     +G   R+C  +G W      + + NY  C         S +  V   +  +  VGY +SL  L ++V+++  F++L C RN IH+H+F +++LRA++ F                           + PP +      C++   +    +  ++ W+ +E L+LH+ + +    D  Y  G  + IGW +P +   +WAT++  + + ECW   D     + W+  +  ++  ++N  LF+NIIRVL  K  + + G  + R  YRKL K+T +L+ +FG++ +I   +     +++   + ++Q++YE    S QGF VA+++CF N EV  E+K+ + +R
Sbjct:   30 LTKEEQITQLVIAKHTCENNIASRSKIPNGFCSAEWDGIVCWPEGPPGKLVSTACPEYIYDFNHKGLAYRRCDNNGTWEQASANKTWANYNECAKFLYHYNHSHEKEVFHRLYLIYTVGYSVSLGSLMVAVVILGYFRRLHCTRNYIHMHLFVSYMLRAISIFVKDVVLYSESPLENMERVTLDDLKSITIAPPVNKTQFIACKVVVTLFMYFLATNYYWILVEGLYLHSLIFMTFFSDRKYLWGFTL-IGWGVPAVFVSIWATVRATFADTECW---DLSAGNLKWIYQVPILMAVVVNFILFLNIIRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIIFNAMPY--TEVSGIPW-LIQMHYEMLFNSFQGFLVAIIYCFCNGEVQAEIKKSWNRR 428          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Medaka
Match: ENSORLT00000023741.2 (vasoactive intestinal polypeptide receptor 2 [Source:NCBI gene;Acc:101170814])

HSP 1 Score: 130.954 bits (328), Expect = 4.145e-33
Identity = 117/399 (29.32%), Postives = 201/399 (50.38%), Query Frame = 1
Query:  139 MSSSSDFCPYDFDKVMCWPPTRPGEIAIQPCPL-YINGLRIRGKTTRQCMESGYWRNYTNYEN-CIS------KKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRAL------THFFNLIPPS------SIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDD--PHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMK-ATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYY-------RQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNK 1245
            + +++  CP +++ V CWP    GE+   PCP  ++     +G  +R C E G+   Y +  + C S      K+L+    +  L  VG+ LSLI L  S  ++  F++L C RN IH+++F +F+LRA+      T  F+    +      S+V         +Y  + A+  W+ +E L+LH  LL+     T   L IY+ IGW IP +  + W   +    +  CW+I D+  P + + W      + + +IN  LFI+IIRVL  K       G   ++YR+L K+T +L+ +FG++ V+   L+   +QI  +    ++++++  + S QG  VA+L+CF+NSEV  E++R         R+   +   LN + +  S  FP    +N+R+  
Sbjct:   47 LQTAAAGCPGEWNNVSCWPNAAVGEVLTLPCPSPFLLFFEKKGNLSRNCTEKGWSSVYPDIRSACYSEITDQPKQLVFYKVVRVLSTVGHSLSLIALLTSTTLICLFRRLHCTRNYIHVNLFVSFMLRAVAVLAKDTLLFSEDEATDCSTQPSLVGCKATLVFFNYF-VMANFFWLLVEGLYLHTLLLVIHTYST--RLSIYMFIGWGIPFVFVVAWIISRVNLEDTSCWEINDNPVPDRLINW----PIMASIIINFILFISIIRVLVQKLRCSEVGGNDQSQYRRLAKSTLLLIPLFGVHYVVFFYLMEPDDQILKQ----IKIFFDLGLGSFQGLIVAVLYCFLNSEVQSELRRSLSLKRCVGREEKLQAVTLNRNGSQRSPTFP----RNVRAQS 430          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Medaka
Match: ENSORLT00000005607.2 (vasoactive intestinal polypeptide receptor [Source:NCBI gene;Acc:101169670])

HSP 1 Score: 129.413 bits (324), Expect = 1.421e-32
Identity = 101/354 (28.53%), Postives = 175/354 (49.44%), Query Frame = 1
Query:  160 CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYWRNYTNYEN-CI-----------SKKLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFF--------NLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMK---ATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            C   +D + CWP    GE   + CP + +     GK  R C  +G+   +  YE+ C+               +  +S+  +  VGY LSLI L I++ ++  F+KL C RN IH+ +F +F+L+A+  F         N    +S    C+         I A+++W+ +E  FL   +         + +  YI + W +P I+ + W+  +Y Y ++ CW+     H+ + W+  +  +L+   NL  F+ I+RVL  K      R N    ++Y+KL K+T  LV VFG++ ++ + L + +    S S   ++++ E  ++S QG  VA L+CF+N EV +E KR +R+
Sbjct:   55 CSGMWDNLTCWPAAPLGETVSKLCPEFFHS---EGKVQRNCTANGWTELFIPYEDACVFNVTLHFLNESPDTHLYFSSVRTVYTVGYALSLISLAIAIAILCLFRKLHCTRNYIHIQLFISFILKAIFIFARDTLLFSENTYHCNSYPVGCKFVPIFSNYCILANYSWLLVEGHFLFTLVSRSFFSLKKHLIW-YIVLSWGLPLIVIVAWSCARYFYEDEGCWE--TGSHEWILWILRVPVLLSICTNLIFFLGILRVLVSKLRMPDARRNEF--SQYKKLIKSTFFLVAVFGLHYMVFVFLRVEA----SSSMSKIKMFAELVLSSTQGLMVATLYCFMNGEVQQEFKRRWRR 396          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Planmine SMEST
Match: SMESG000071460.1 (SMESG000071460.1)

HSP 1 Score: 394.43 bits (1012), Expect = 1.443e-137
Identity = 211/212 (99.53%), Postives = 212/212 (100.00%), Query Frame = 1
Query:  652 MRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNKRAATCLTNNNGSNH 1287
            MRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLELLYPILTTLINLTLFINIIRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERK+QNIRSNKRAATCLTNNNGSNH
Sbjct:    1 MRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLELLYPILTTLINLTLFINIIRVLFMKATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKTQNIRSNKRAATCLTNNNGSNH 212          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Planmine SMEST
Match: SMESG000081404.1 (SMESG000081404.1)

HSP 1 Score: 201.445 bits (511), Expect = 7.705e-60
Identity = 142/377 (37.67%), Postives = 210/377 (55.70%), Query Frame = 1
Query:  184 MCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYWRNYTNYENCISKKLIVIAS----MNH------LGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPP--SSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKAT-----DRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLLSEQINSESFEI---VQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQRN--------DRRTCLNEHSNPLSMIFPERKSQN 1230
            MCW   +     I+ CP Y NG +  GK ++ C   G W   T+Y  C+  ++    S    MN       LG +GYG+S+  L +++ +M +F+KL C RNTIH+H+F +FLLR   HFF          +W C+L AA+    I AS+TWVFIEAL+LHNT+ +H++ ++   L  YI +GW +P ++  +    +YL+ +  CW I +    R  W+ + YP +T ++N+  F+NI R +F+K       DR      +RYR+L K+T ILV+VFG+Y ++ IP+ L +    S S+ +   +QLYY H   + QGF VA LFCF N EVIKEVKR +   N        D R   N  S   + +FP RK+ +
Sbjct:    1 MCWKAAQRNSTIIKTCPDYYNGFKKDGKVSKSCNNIGKWSK-TDYSGCVPSEMWSYLSNYETMNKIRLVETLGSIGYGISVFCLVVAIGIMLKFRKLRCNRNTIHIHLFISFLLRGCIHFFEKAYGIRELTLWACKLMAAVANFLIEASYTWVFIEALYLHNTIFVHVLSESKAWLWFYIGLGWGLPFLVICILTGARYLFDDTGCWIIDNLNISR--WILICYPTITIVLNVFFFVNITREIFIKIRQEPIHDR------HRYRRLTKSTFILVLVFGLYHLLFIPVELNNTGKKSTSYSVLYMIQLYYTHLFVTFQGFIVAFLFCFFNGEVIKEVKRIFFHSNNGNMLRSVDCRYTKNTLSGEQNRLFPPRKNNS 368          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Planmine SMEST
Match: SMESG000047057.1 (SMESG000047057.1)

HSP 1 Score: 195.667 bits (496), Expect = 2.536e-57
Identity = 125/384 (32.55%), Postives = 214/384 (55.73%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNLSRYMSSSSDF------CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYWR-----NYTNYENCISK----KLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMK-----ATDRSNGLVNNRYRKLFKATAILVIVFGIYDVILIPLVLL---SEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            I Q++Q ES+  +  +CL    +++ S D       CP  +D +MCWP T  G++    CP Y++  +I G  T++C  +G W       +TNY +C SK           +  +G VGY +S++ L I++I++  F++L C RN IHL++F+AF  RA+ H+      +  ++ CR    I      AS   +F EA+++HN +  H    +     +YI + W++P  +  +W+ L+Y + N  CW + +D H R +W    Y IL TL+N  +FI +   L  K     +T+R       +++KL ++  ILVIVFG+Y+V+ +P+ ++   ++   ++  E+++LY+ H   SCQGF V+LL CF+NSEV +E+KR+ ++
Sbjct:   14 IPQDKQMESIIEEHIKCLGRMSFLNYSLDIVTINSKCPVSWDGIMCWPETEAGKLVSSRCPNYVDSFQINGTVTKKCTNNGTWYLKDNVTWTNYSDCKSKIDSLAFKQFEKIEKIGQVGYAISILSLVIAIIILCSFRRLRCNRNYIHLNLFFAFFFRAIFHYLTSFLQTEKIY-CRALRVIYNYFTQASFQSIFTEAIYMHNMIFYHTFDSSKINTPVYIVLCWVVPGFVIGIWSLLRYKFNNVYCWDLSNDKHNRDFWFLNAYVILLTLVNSVIFIILTCSLCSKMNSHISTERE------KFKKLARSICILVIVFGVYNVVFVPVEIICAIADNATAKKTELIKLYFHHIFNSCQGFLVSLLLCFVNSEVHREIKRFIQK 390          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Planmine SMEST
Match: SMESG000047057.1 (SMESG000047057.1)

HSP 1 Score: 196.052 bits (497), Expect = 2.606e-57
Identity = 118/386 (30.57%), Postives = 209/386 (54.15%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNLSRYMSSSSDF------CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYWR-----NYTNYENCISK----KLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKAT----DRSNGLVNN---RYRKLFKATAILVIVFGIYDVILIPLVLL---SEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            I Q++Q ES+  +  +CL    +++ S D       CP  +D +MCWP T  G++    CP Y++  +I G  T++C  +G W       +TNY +C SK           +  +G VGY +S++ L I++I++  F++L C RN IHL++F+AF  RA+ H+      +  ++ CR    I      AS   +F EA+++HN +  H    +     +YI + W++P  +  +W+ L+Y + N  CW + +D H R +W             + L   +  V+F+  T     + N  ++    +++KL ++  ILVIVFG+Y+V+ +P+ ++   ++   ++  E+++LY+ H   SCQGF V+LL CF+NSEV +E+KR+ ++
Sbjct:   24 IPQDKQMESIIEEHIKCLGRMSFLNYSLDIVTINSKCPVSWDGIMCWPETEAGKLVSSRCPNYVDSFQINGTVTKKCTNNGTWYLKDNVTWTNYSDCKSKIDSLAFKQFEKIEKIGQVGYAISILSLVIAIIILCSFRRLRCNRNYIHLNLFFAFFFRAIFHYLTSFLQTEKIY-CRALRVIYNYFTQASFQSIFTEAIYMHNMIFYHTFDSSKINTPVYIVLCWVVPGFVIGIWSLLRYKFNNVYCWDLSNDKHNRDFWF--------LNAYVILLTLVNSVIFIILTCSLCSKMNSHISTEREKFKKLARSICILVIVFGVYNVVFVPVEIICAIADNATAKKTELIKLYFHHIFNSCQGFLVSLLLCFVNSEVHREIKRFIQK 400          
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Planmine SMEST
Match: SMESG000047057.1 (SMESG000047057.1)

HSP 1 Score: 196.052 bits (497), Expect = 2.607e-57
Identity = 118/386 (30.57%), Postives = 209/386 (54.15%), Query Frame = 1
Query:   70 ISQEEQHESVYGKLQECLNLSRYMSSSSDF------CPYDFDKVMCWPPTRPGEIAIQPCPLYINGLRIRGKTTRQCMESGYWR-----NYTNYENCISK----KLIVIASMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRALTHFFNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEAXXXXXXXXXXXMRDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYWLEXXXXXXXXXXXXXXXXXXXRVLFMKAT----DRSNGLVNN---RYRKLFKATAILVIVFGIYDVILIPLVLL---SEQINSESFEIVQLYYEHTMTSCQGFFVALLFCFINSEVIKEVKRYYRQ 1152
            I Q++Q ES+  +  +CL    +++ S D       CP  +D +MCWP T  G++    CP Y++  +I G  T++C  +G W       +TNY +C SK           +  +G VGY +S++ L I++I++  F++L C RN IHL++F+AF  RA+ H+      +  ++ CR    I      AS   +F EA+++HN +  H    +     +YI + W++P  +  +W+ L+Y + N  CW + +D H R +W             + L   +  V+F+  T     + N  ++    +++KL ++  ILVIVFG+Y+V+ +P+ ++   ++   ++  E+++LY+ H   SCQGF V+LL CF+NSEV +E+KR+ ++
Sbjct:   33 IPQDKQMESIIEEHIKCLGRMSFLNYSLDIVTINSKCPVSWDGIMCWPETEAGKLVSSRCPNYVDSFQINGTVTKKCTNNGTWYLKDNVTWTNYSDCKSKIDSLAFKQFEKIEKIGQVGYAISILSLVIAIIILCSFRRLRCNRNYIHLNLFFAFFFRAIFHYLTSFLQTEKIY-CRALRVIYNYFTQASFQSIFTEAIYMHNMIFYHTFDSSKINTPVYIVLCWVVPGFVIGIWSLLRYKFNNVYCWDLSNDKHNRDFWF--------LNAYVILLTLVNSVIFIILTCSLCSKMNSHISTEREKFKKLARSICILVIVFGVYNVVFVPVEIICAIADNATAKKTELIKLYFHHIFNSCQGFLVSLLLCFVNSEVHREIKRFIQK 409          
The following BLAST results are available for this feature:
BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PTH1R6.817e-3827.23parathyroid hormone 1 receptor [Source:HGNC Symbol... [more]
PTH1R4.371e-3727.23parathyroid hormone 1 receptor [Source:HGNC Symbol... [more]
PTH1R4.371e-3727.23parathyroid hormone 1 receptor [Source:HGNC Symbol... [more]
PTH1R4.371e-3727.23parathyroid hormone 1 receptor [Source:HGNC Symbol... [more]
PTH1R4.371e-3727.23parathyroid hormone 1 receptor [Source:HGNC Symbol... [more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
seb-34.509e-1823.18SEcretin/class B GPCR; Secretin receptor-like prot... [more]
pdfr-13.160e-1525.00Calcitonin receptor-like protein 1 [Source:UniPro... [more]
pdfr-13.160e-1525.00Calcitonin receptor-like protein 1 [Source:UniPro... [more]
pdfr-13.583e-1525.00Calcitonin receptor-like protein 1 [Source:UniPro... [more]
pdfr-13.583e-1525.00Calcitonin receptor-like protein 1 [Source:UniPro... [more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Dh44-R22.546e-2628.42gene:FBgn0033744 transcript:FBtr0113075[more]
Dh44-R22.723e-2628.42gene:FBgn0033744 transcript:FBtr0087936[more]
Dh44-R11.604e-2528.69gene:FBgn0033932 transcript:FBtr0087485[more]
Pdfr7.197e-2127.54gene:FBgn0260753 transcript:FBtr0070436[more]
hec9.264e-2129.28gene:FBgn0030437 transcript:FBtr0343652[more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pth1r4.263e-3826.47parathyroid hormone 1 receptor [Source:ZFIN;Acc:ZD... [more]
pth1r4.474e-3826.47parathyroid hormone 1 receptor [Source:ZFIN;Acc:ZD... [more]
pth2rb1.542e-3725.66parathyroid hormone 2 receptor b [Source:ZFIN;Acc:... [more]
pth2rb2.430e-3725.61parathyroid hormone 2 receptor b [Source:ZFIN;Acc:... [more]
pth3r3.210e-3628.46parathyroid hormone 3 receptor [Source:ZFIN;Acc:ZD... [more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ccdc229.450e-3728.04coiled-coil domain containing 22 [Source:Xenbase;A... [more]
ccdc222.251e-3628.15coiled-coil domain containing 22 [Source:Xenbase;A... [more]
ccdc221.881e-3527.85coiled-coil domain containing 22 [Source:Xenbase;A... [more]
ccdc221.980e-3527.85coiled-coil domain containing 22 [Source:Xenbase;A... [more]
ccdc222.002e-3527.85coiled-coil domain containing 22 [Source:Xenbase;A... [more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pth1r7.435e-3728.46parathyroid hormone 1 receptor [Source:MGI Symbol;... [more]
Pth1r7.435e-3728.46parathyroid hormone 1 receptor [Source:MGI Symbol;... [more]
Pth1r7.435e-3728.46parathyroid hormone 1 receptor [Source:MGI Symbol;... [more]
Pth2r2.819e-3327.94parathyroid hormone 2 receptor [Source:MGI Symbol;... [more]
Sctr2.106e-3128.61secretin receptor [Source:MGI Symbol;Acc:MGI:24417... [more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P25107|PTH1R_DIDVI1.473e-4328.78Parathyroid hormone/parathyroid hormone-related pe... [more]
sp|P50133|PTH1R_PIG8.018e-3827.48Parathyroid hormone/parathyroid hormone-related pe... [more]
sp|Q9TU31|PTH1R_CANLF1.352e-3627.01Parathyroid hormone/parathyroid hormone-related pe... [more]
sp|Q1LZF7|PTH1R_BOVIN1.481e-3627.25Parathyroid hormone/parathyroid hormone-related pe... [more]
sp|Q03431|PTH1R_HUMAN2.099e-3627.23Parathyroid hormone/parathyroid hormone-related pe... [more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A504YH661.722e-6135.48Parathyroid hormone/parathyroid hormone peptide re... [more]
A0A4E0RXW43.706e-6135.22Parathyroid hormone/parathyroid hormone peptide re... [more]
A0A0A0P3Y47.612e-6034.96Family B1 G-protein coupled receptor OS=Fasciola g... [more]
A0A4S2LH172.783e-5735.43Uncharacterized protein OS=Opisthorchis felineus O... [more]
A0A3Q0KSN31.587e-5434.94Putative g-protein coupled receptor OS=Schistosoma... [more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pth2ra1.341e-4126.91parathyroid hormone 2 receptor [Source:NCBI gene;A... [more]
pth2ra1.564e-4126.91parathyroid hormone 2 receptor [Source:NCBI gene;A... [more]
pth3r1.464e-3927.08parathyroid hormone/parathyroid hormone-related pe... [more]
pth3r1.257e-3827.19parathyroid hormone/parathyroid hormone-related pe... [more]
pth1r1.543e-3826.76parathyroid hormone 1 receptor [Source:ZFIN;Acc:ZD... [more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pth1r3.285e-4029.53parathyroid hormone 1 receptor [Source:ZFIN;Acc:ZD... [more]
ENSPMAT00000000542.15.741e-2828.07pep scaffold:Pmarinus_7.0:GL476735:164228:192153:1... [more]
ENSPMAT00000004899.13.719e-2429.07pep scaffold:Pmarinus_7.0:GL476767:721819:758871:-... [more]
ENSPMAT00000009958.13.872e-2129.09pep scaffold:Pmarinus_7.0:GL477206:37870:64312:-1 ... [more]
ENSPMAT00000004243.11.646e-1826.85pep scaffold:Pmarinus_7.0:GL484465:15708:23345:-1 ... [more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pth2ra5.154e-4128.12parathyroid hormone 2 receptor [Source:NCBI gene;A... [more]
pth3r1.075e-3829.72parathyroid hormone/parathyroid hormone-related pe... [more]
pth1r1.429e-3826.85parathyroid hormone 1 receptor [Source:NCBI gene;A... [more]
ENSORLT00000023741.24.145e-3329.32vasoactive intestinal polypeptide receptor 2 [Sour... [more]
ENSORLT00000005607.21.421e-3228.53vasoactive intestinal polypeptide receptor [Source... [more]
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BLAST of Parathyroid hormone/parathyroid hormone peptide receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000071460.11.443e-13799.53SMESG000071460.1[more]
SMESG000081404.17.705e-6037.67SMESG000081404.1[more]
SMESG000047057.12.536e-5732.55SMESG000047057.1[more]
SMESG000047057.12.606e-5730.57SMESG000047057.1[more]
SMESG000047057.12.607e-5730.57SMESG000047057.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026220 ID=SMED30026220|Name=Parathyroid hormone/parathyroid hormone peptide receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=1397bp
TTTACGGAGTTTTCATAGAAATTATAATTAATAAGAATTTTGCCAGAAAA
ATAAATGCACTTTGTTACAATTTCTCAGGAAGAACAACACGAATCTGTAT
ACGGAAAATTGCAAGAATGTCTCAATTTATCCAGATACATGTCATCAAGT
TCGGATTTTTGTCCTTATGATTTTGATAAAGTTATGTGCTGGCCACCAAC
CAGGCCTGGGGAAATTGCCATTCAACCTTGCCCTCTATATATCAACGGGC
TGAGGATCAGAGGGAAAACGACTCGACAATGCATGGAATCCGGTTACTGG
CGCAATTATACAAATTATGAAAACTGTATCAGCAAAAAGCTTATTGTCAT
TGCTTCAATGAATCATTTGGGCCATGTGGGATACGGTCTGTCATTAATAT
TTCTGGGAATAAGTGTTATTGTAATGACAAGATTCAAAAAATTGAGCTGT
CCAAGAAACACCATCCATTTACATGTGTTTTACGCATTCTTGTTGAGAGC
CCTCACACATTTTTTCAATCTGATTCCTCCATCATCGATCGTATGGCTTT
GTCGACTGTTCGCAGCTATAGACTATCTCTCCATCACCGCCAGCCATACA
TGGGTCTTTATTGAAGCTCTATTTCTACACAACACCTTGCTGTTGCATCT
CATGCGTGACACTCCTTACACTTTGGGAATTTATATCAGTATCGGATGGA
TCATTCCATGCATTCTTGGGATAGTATGGGCAACTCTGAAATATCTTTAC
GGGAACAAGGAATGTTGGCAGATATACGATGACCCTCATAAACGAGTTTA
TTGGTTAGAATTATTATATCCGATTCTTACAACATTAATCAACCTCACCC
TGTTTATAAACATCATTCGGGTTTTGTTTATGAAGGCTACTGATCGCAGC
AATGGACTGGTGAATAACAGATATAGGAAATTATTCAAAGCCACTGCCAT
TTTGGTAATTGTGTTTGGGATATATGACGTCATTTTAATTCCACTTGTTT
TACTGAGTGAGCAAATAAATTCAGAGTCATTTGAAATTGTCCAACTCTAT
TATGAACATACAATGACTTCATGTCAGGGATTTTTCGTGGCATTACTCTT
TTGCTTCATAAATTCTGAAGTTATAAAAGAAGTCAAGCGATATTACAGAC
AACGAAATGACCGAAGAACATGCTTAAACGAGCATTCAAATCCGTTATCA
ATGATATTTCCTGAGAGGAAATCTCAAAATATCCGATCCAACAAGAGAGC
GGCGACATGTCTAACGAACAATAATGGTTCAAACCACTGAAAATTATCTG
TGTACACATTTCACGATTTTATTTCAAACAAAAATTATTGTTGATTTTAA
TAATCCATGTTTATTTTATTAAAAAAATTTCAATAAATCTTTGACGC
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protein sequence of SMED30026220-orf-1

>SMED30026220-orf-1 ID=SMED30026220-orf-1|Name=SMED30026220-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=412bp
MHFVTISQEEQHESVYGKLQECLNLSRYMSSSSDFCPYDFDKVMCWPPTR
PGEIAIQPCPLYINGLRIRGKTTRQCMESGYWRNYTNYENCISKKLIVIA
SMNHLGHVGYGLSLIFLGISVIVMTRFKKLSCPRNTIHLHVFYAFLLRAL
THFFNLIPPSSIVWLCRLFAAIDYLSITASHTWVFIEALFLHNTLLLHLM
RDTPYTLGIYISIGWIIPCILGIVWATLKYLYGNKECWQIYDDPHKRVYW
LELLYPILTTLINLTLFINIIRVLFMKATDRSNGLVNNRYRKLFKATAIL
VIVFGIYDVILIPLVLLSEQINSESFEIVQLYYEHTMTSCQGFFVALLFC
FINSEVIKEVKRYYRQRNDRRTCLNEHSNPLSMIFPERKSQNIRSNKRAA
TCLTNNNGSNH*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0002032epidermal cell
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR000832GPCR_2_secretin-like
IPR001879GPCR_2_extracellular_dom
IPR017983GPCR_2_secretin-like_CS
IPR017981GPCR_2-like
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0004888transmembrane signaling receptor activity
GO:0004871signal transducer activity
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
GO:0005886plasma membrane
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007166cell surface receptor signaling pathway
GO:0007165signal transduction