DDHD domain-containing protein

Overview
NameDDHD domain-containing protein
Smed IDSMED30026215
Length (bp)2895
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DDHD domain-containing protein (SMED30026215) t-SNE clustered cells

Violin plots show distribution of expression levels for DDHD domain-containing protein (SMED30026215) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DDHD domain-containing protein (SMED30026215) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DDHD domain-containing protein (SMED30026215) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30026215

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30026215h1SMcG0022547 SmedASXL_016413SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30026215h1SMcG0022547 dd_Smed_v4_13571_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30026215h1SMcG0022547 dd_Smed_v4_13571_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30026215h1SMcG0022547 dd_Smed_v4_13571_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30026215h1SMcG0022547 dd_Smed_v4_13001_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30026215h1SMcG0022547 dd_Smed_v6_13001_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of DDHD domain-containing protein vs. Ensembl Human
Match: DDHD1 (DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714])

HSP 1 Score: 381.333 bits (978), Expect = 2.796e-118
Identity = 197/467 (42.18%), Postives = 285/467 (61.03%), Query Frame = 2
Query:  473 GDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLN--VKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            G LYEVDV     +P+YWN  D      P++RG WF   +WQPL+ E+ +N IE+EHL  +      +  + F  ++S+ +     V S  +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK    TH+VFV+HGIGQKM  G I    + +R   RK+ ++ F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE L   + +  D+   S+E R  L  +L + K ++  +E  +        T      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:  132 GGLYEVDVTQGECYPVYWNQAD----KIPVMRGQWFIDGTWQPLEEEE-SNLIEQEHLNCF---RGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLKEIEERLHGLKASSMTQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 567          
BLAST of DDHD domain-containing protein vs. Ensembl Human
Match: DDHD1 (DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714])

HSP 1 Score: 383.645 bits (984), Expect = 4.960e-118
Identity = 198/468 (42.31%), Postives = 286/468 (61.11%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLN--VKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVDV     +P+YWN  D      P++RG WF   +WQPL+ E+ +N IE+EHL  +      +  + F  ++S+ +     V S  +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK    TH+VFV+HGIGQKM  G I    + +R   RK+ ++ F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE L   + +  D+   S+E R  L  +L + K ++  +E  +        T      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:  260 RGGLYEVDVTQGECYPVYWNQAD----KIPVMRGQWFIDGTWQPLEEEE-SNLIEQEHLNCF---RGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLKEIEERLHGLKASSMTQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 696          

HSP 2 Score: 53.1434 bits (126), Expect = 2.743e-6
Identity = 23/39 (58.97%), Postives = 29/39 (74.36%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFREL 418
            ++  L PE++RWFYKE+K  W PF GYDSLR+E  FR L
Sbjct:  159 VVTELGPEEVRWFYKEDKKTWKPFIGYDSLRIELAFRTL 197          
BLAST of DDHD domain-containing protein vs. Ensembl Human
Match: DDHD1 (DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714])

HSP 1 Score: 383.645 bits (984), Expect = 9.797e-118
Identity = 198/468 (42.31%), Postives = 286/468 (61.11%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLN--VKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVDV     +P+YWN  D      P++RG WF   +WQPL+ E+ +N IE+EHL  +      +  + F  ++S+ +     V S  +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK    TH+VFV+HGIGQKM  G I    + +R   RK+ ++ F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE L   + +  D+   S+E R  L  +L + K ++  +E  +        T      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:  260 RGGLYEVDVTQGECYPVYWNQAD----KIPVMRGQWFIDGTWQPLEEEE-SNLIEQEHLNCF---RGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLKEIEERLHGLKASSMTQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 696          

HSP 2 Score: 53.1434 bits (126), Expect = 2.866e-6
Identity = 23/39 (58.97%), Postives = 29/39 (74.36%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFREL 418
            ++  L PE++RWFYKE+K  W PF GYDSLR+E  FR L
Sbjct:  159 VVTELGPEEVRWFYKEDKKTWKPFIGYDSLRIELAFRTL 197          
BLAST of DDHD domain-containing protein vs. Ensembl Human
Match: DDHD1 (DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714])

HSP 1 Score: 376.326 bits (965), Expect = 1.614e-117
Identity = 201/503 (39.96%), Postives = 286/503 (56.86%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETAD-------------------------------------GFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVDV     +P+YWN  D      P++RG WF   +WQPL+ E+ +N IE+EHL  +      E  D                                     G  ++ SQ +H    S  +   H+DW+  D V++Y+D+ +      +  +LG +K    G++L+RGY  EA +EDK    TH+VFV+HGIGQKM  G I    + +R   RK+ ++ F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE L   + +  D+   S+E R  L  +L + K ++  +E  +        T      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:   29 RGGLYEVDVTQGECYPVYWNQAD----KIPVMRGQWFIDGTWQPLEEEE-SNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDVVYHLPPFSLPSLFKWRRYKESTDATGLKRKHSQAVH----SFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLKEIEERLHGLKASSMTQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 499          
BLAST of DDHD domain-containing protein vs. Ensembl Human
Match: DDHD1 (DDHD domain containing 1 [Source:HGNC Symbol;Acc:HGNC:19714])

HSP 1 Score: 381.719 bits (979), Expect = 2.989e-117
Identity = 198/475 (41.68%), Postives = 287/475 (60.42%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKL---------HLNVKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVDV     +P+YWN  D      P++RG WF   +WQPL+ E+ +N IE+EHL  +      +  + F  ++S+ +         +  V S  +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK    TH+VFV+HGIGQKM  G I    + +R   RK+ ++ F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE L   + +  D+   S+E R  L  +L + K ++  +E  +        T      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:  260 RGGLYEVDVTQGECYPVYWNQAD----KIPVMRGQWFIDGTWQPLEEEE-SNLIEQEHLNCF---RGQQMQENFDIEVSKSIDGKDGSGINYSAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLKEIEERLHGLKASSMTQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 703          

HSP 2 Score: 53.1434 bits (126), Expect = 2.569e-6
Identity = 23/39 (58.97%), Postives = 29/39 (74.36%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFREL 418
            ++  L PE++RWFYKE+K  W PF GYDSLR+E  FR L
Sbjct:  159 VVTELGPEEVRWFYKEDKKTWKPFIGYDSLRIELAFRTL 197          
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Match: ipla-1 (Intracelllar PhosphoLipase A family [Source:UniProtKB/TrEMBL;Acc:G4SGU1])

HSP 1 Score: 230.72 bits (587), Expect = 9.096e-64
Identity = 173/534 (32.40%), Postives = 259/534 (48.50%), Query Frame = 2
Query:  329 KIRWFYKENK--LWIPFCGYDSLRLETKFR------------------------------ELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQ-QISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLP--------KLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIY 1807
            ++RWF++E K  LW PF G DS+ LE K+R                              E+ N ++   +     +V+ G  Y+V+  N    PIYW   DD +E   I RG+WF    +QPL+   ++++IEK HL+ + +    E    F++ + S K  L    L V GY I W     + ++    +  +R+   L    + L RGY+ EA   D   +I+HL+ V+HGIGQK     I    +++R       +K +P   E   R  FLPVEWR +L LD    D IT  +   +R  +NSTA+D++YY SP++R E++  +  +LNR Y +F A +P F    G VS   HSLG+V+ YD+L  +SP  +++   T   D   K           D N ++E    LE + L + EQ   N               + G + K+L         K++ LF VGSPL VFL +RG +     + D +      +RVFNIFHP DPV YRLEP     Y +I P++++
Sbjct:   63 EVRWFFQEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQ-YKVNKDNSKIDPIYWK--DDSKE---IRRGSWFS-PDYQPLEM-PLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVL--AELHVDGYDIRWSSVIDISLH-QKGNAILRY---LWAKSTPLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYP---EEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQF---NGHVSVFGHSLGSVICYDVLTQYSPLMLFDKYVTKSIDEYLKRD---------DTNASEEARKALEAMKLAR-EQLRDN---------------LEGGIHKLLVTKEEQLEFKVKYLFAVGSPLGVFLTMRGGE-----STDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRPIKLF 546          
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Match: ipla-1 (Intracelllar PhosphoLipase A family [Source:UniProtKB/TrEMBL;Acc:G4SGU1])

HSP 1 Score: 230.335 bits (586), Expect = 1.386e-63
Identity = 170/535 (31.78%), Postives = 259/535 (48.41%), Query Frame = 2
Query:  329 KIRWFYKENK--LWIPFCGYDSLRLETKFR------------------------------ELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQ-QISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDN----KDKTSHENRMQLFSDLNVAKEKVHH-----LELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIY 1807
            ++RWF++E K  LW PF G DS+ LE K+R                              E+ N ++   +     +V+ G  Y+V+  N    PIYW   DD +E   I RG+WF    +QPL+   ++++IEK HL+ + +    E    F++ + S K  L    L V GY I W     + ++    +  +R+   L    + L RGY+ EA   D   +I+HL+ V+HGIGQK     I    +++R       +K +P   E   R  FLPVEWR +L LD    D IT  +   +R  +NSTA+D++YY SP++R E++  +  +LNR Y +F A +P F    G VS   HSLG+V+ YD+L  +SP  +++   T   D      D  + E   +    + +A+E++       +  L++TK EQ         F                   K++ LF VGSPL VFL +RG +     + D +      +RVFNIFHP DPV YRLEP     Y +I P++++
Sbjct:   89 EVRWFFQEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQ-YKVNKDNSKIDPIYWK--DDSKE---IRRGSWFS-PDYQPLEM-PLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVL--AELHVDGYDIRWSSVIDISLH-QKGNAILRY---LWAKSTPLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYP---EEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQF---NGHVSVFGHSLGSVICYDVLTQYSPLMLFDKYVTKSIDEYLKRDDTNASEEARKALEAMKLAREQLRDNLEGGIHKLLVTKEEQ-------LEF-------------------KVKYLFAVGSPLGVFLTMRGGE-----STDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRPIKLF 572          
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Match: ipla-1 (Intracelllar PhosphoLipase A family [Source:UniProtKB/TrEMBL;Acc:G4SGU1])

HSP 1 Score: 230.335 bits (586), Expect = 1.696e-63
Identity = 173/534 (32.40%), Postives = 259/534 (48.50%), Query Frame = 2
Query:  329 KIRWFYKENK--LWIPFCGYDSLRLETKFR------------------------------ELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQ-QISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLP--------KLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIY 1807
            ++RWF++E K  LW PF G DS+ LE K+R                              E+ N ++   +     +V+ G  Y+V+  N    PIYW   DD +E   I RG+WF    +QPL+   ++++IEK HL+ + +    E    F++ + S K  L    L V GY I W     + ++    +  +R+   L    + L RGY+ EA   D   +I+HL+ V+HGIGQK     I    +++R       +K +P   E   R  FLPVEWR +L LD    D IT  +   +R  +NSTA+D++YY SP++R E++  +  +LNR Y +F A +P F    G VS   HSLG+V+ YD+L  +SP  +++   T   D   K           D N ++E    LE + L + EQ   N               + G + K+L         K++ LF VGSPL VFL +RG +     + D +      +RVFNIFHP DPV YRLEP     Y +I P++++
Sbjct:   87 EVRWFFQEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQ-YKVNKDNSKIDPIYWK--DDSKE---IRRGSWFS-PDYQPLEM-PLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVL--AELHVDGYDIRWSSVIDISLH-QKGNAILRY---LWAKSTPLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYP---EEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQF---NGHVSVFGHSLGSVICYDVLTQYSPLMLFDKYVTKSIDEYLKRD---------DTNASEEARKALEAMKLAR-EQLRDN---------------LEGGIHKLLVTKEEQLEFKVKYLFAVGSPLGVFLTMRGGE-----STDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRPIKLF 570          
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Match: ipla-1 (Intracelllar PhosphoLipase A family [Source:UniProtKB/TrEMBL;Acc:G4SGU1])

HSP 1 Score: 229.95 bits (585), Expect = 1.920e-63
Identity = 173/534 (32.40%), Postives = 259/534 (48.50%), Query Frame = 2
Query:  329 KIRWFYKENK--LWIPFCGYDSLRLETKFR------------------------------ELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQ-QISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLP--------KLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIY 1807
            ++RWF++E K  LW PF G DS+ LE K+R                              E+ N ++   +     +V+ G  Y+V+  N    PIYW   DD +E   I RG+WF    +QPL+   ++++IEK HL+ + +    E    F++ + S K  L    L V GY I W     + ++    +  +R+   L    + L RGY+ EA   D   +I+HL+ V+HGIGQK     I    +++R       +K +P   E   R  FLPVEWR +L LD    D IT  +   +R  +NSTA+D++YY SP++R E++  +  +LNR Y +F A +P F    G VS   HSLG+V+ YD+L  +SP  +++   T   D   K           D N ++E    LE + L + EQ   N               + G + K+L         K++ LF VGSPL VFL +RG +     + D +      +RVFNIFHP DPV YRLEP     Y +I P++++
Sbjct:   75 EVRWFFQEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQ-YKVNKDNSKIDPIYWK--DDSKE---IRRGSWFS-PDYQPLEM-PLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVL--AELHVDGYDIRWSSVIDISLH-QKGNAILRY---LWAKSTPLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYP---EEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQF---NGHVSVFGHSLGSVICYDVLTQYSPLMLFDKYVTKSIDEYLKRD---------DTNASEEARKALEAMKLAR-EQLRDN---------------LEGGIHKLLVTKEEQLEFKVKYLFAVGSPLGVFLTMRGGE-----STDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRPIKLF 558          
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Match: ipla-1 (Intracelllar PhosphoLipase A family [Source:UniProtKB/TrEMBL;Acc:G4SGU1])

HSP 1 Score: 229.95 bits (585), Expect = 1.920e-63
Identity = 173/534 (32.40%), Postives = 259/534 (48.50%), Query Frame = 2
Query:  329 KIRWFYKENK--LWIPFCGYDSLRLETKFR------------------------------ELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQ-QISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLP--------KLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIY 1807
            ++RWF++E K  LW PF G DS+ LE K+R                              E+ N ++   +     +V+ G  Y+V+  N    PIYW   DD +E   I RG+WF    +QPL+   ++++IEK HL+ + +    E    F++ + S K  L    L V GY I W     + ++    +  +R+   L    + L RGY+ EA   D   +I+HL+ V+HGIGQK     I    +++R       +K +P   E   R  FLPVEWR +L LD    D IT  +   +R  +NSTA+D++YY SP++R E++  +  +LNR Y +F A +P F    G VS   HSLG+V+ YD+L  +SP  +++   T   D   K           D N ++E    LE + L + EQ   N               + G + K+L         K++ LF VGSPL VFL +RG +     + D +      +RVFNIFHP DPV YRLEP     Y +I P++++
Sbjct:   75 EVRWFFQEPKGTLWNPFNGRDSIMLEIKYRKEKGIELDEAMQEIYDESLTHYKMEMKDEPEIENGNIGMEQEKPMVVVMNGQ-YKVNKDNSKIDPIYWK--DDSKE---IRRGSWFS-PDYQPLEM-PLSDQIEKNHLQCFRNQMIPEGTTVFSKSETSNKPVL--AELHVDGYDIRWSSVIDISLH-QKGNAILRY---LWAKSTPLRRGYEKEADWNDAAAEISHLILVVHGIGQKGYENLIAQNANQVRDGVVSAMEKVYP---EEKSRPMFLPVEWRSALKLDNGLTDNITIPKMSSMRASLNSTAMDVMYYQSPLFRTEIVRGVVSQLNRTYKLFKANNPQF---NGHVSVFGHSLGSVICYDVLTQYSPLMLFDKYVTKSIDEYLKRD---------DTNASEEARKALEAMKLAR-EQLRDN---------------LEGGIHKLLVTKEEQLEFKVKYLFAVGSPLGVFLTMRGGE-----STDLLSKATNVERVFNIFHPYDPVAYRLEPFFAPEYRHIRPIKLF 558          
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Match: PAPLA1 (gene:FBgn0031990 transcript:FBtr0344863)

HSP 1 Score: 134.035 bits (336), Expect = 6.135e-32
Identity = 134/516 (25.97%), Postives = 218/516 (42.25%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK----LWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHL-NVKSLVVGG--YHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQK--MKGGDITYQVSKIRAVCRKVTKKFFPLLEEAN--QRVEFLPVEWRKSLVLDGNTVD----LITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANF-PSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRI 1804
            + +P  P    WFYK +     +W PF  YDS  LET             +     I V G  Y+V++  R   P+YW       ++  + R +WF    ++ +DS+ +    +   L       S+ET      +  QK+ L N + +V  G    + +  Q +   +  S    +R R+        + R        + +   + HL+F++HGIG    +K   +   V   R + +++ +  +    +     RVE LP+ W   L  +   +D     IT      LRN  N T LD+L+Y+SP Y  +++ ++   LN +Y  +  R P F    G VS   HSLG+++L+D+L +  P K  E     + D   +     ++QL +   + K+        V      E T +    + +  F P  F               F +GSP+ +F+ +RG+    L   D  LP   C   +NIFHP DPV YR+E L+N     I PV I
Sbjct:   16 VAIPYSPVVAHWFYKRSVDTKFIWTPFSHYDSALLETSLN---------LDDSTLIIPVEGGRYDVNIKERTKTPVYWEG-----KAIEVRRCSWF----YKGVDSKYVPYTEDTAALLEAEYKRSAETG-----EWHQKIMLANGEQVVFHGPTVIVHFLPQQNADTWGASTQGSMRPRV--------VKRDLDDFTIEQGESQRVDHLLFMVHGIGSACDLKMRSVEEVVDDFRVIAQQLVQSHYKNSTDMGLVGRVEVLPISWHGHLHSEELGIDEKLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEF---NGGVSLAGHSLGSLILFDLLCHQEPLKESEEENKENPDQLPQKQSSQKVQLPTSDPLPKQ--------VSYAMGPEGTGQPVITYTQLIFHPKKF---------------FALGSPIGMFVTIRGIDKLGL---DFHLPT--CPGFYNIFHPFDPVAYRIEALVNPDMNGIRPVLI 469          
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Match: PAPLA1 (gene:FBgn0031990 transcript:FBtr0302595)

HSP 1 Score: 134.035 bits (336), Expect = 6.135e-32
Identity = 134/516 (25.97%), Postives = 218/516 (42.25%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK----LWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHL-NVKSLVVGG--YHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQK--MKGGDITYQVSKIRAVCRKVTKKFFPLLEEAN--QRVEFLPVEWRKSLVLDGNTVD----LITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANF-PSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRI 1804
            + +P  P    WFYK +     +W PF  YDS  LET             +     I V G  Y+V++  R   P+YW       ++  + R +WF    ++ +DS+ +    +   L       S+ET      +  QK+ L N + +V  G    + +  Q +   +  S    +R R+        + R        + +   + HL+F++HGIG    +K   +   V   R + +++ +  +    +     RVE LP+ W   L  +   +D     IT      LRN  N T LD+L+Y+SP Y  +++ ++   LN +Y  +  R P F    G VS   HSLG+++L+D+L +  P K  E     + D   +     ++QL +   + K+        V      E T +    + +  F P  F               F +GSP+ +F+ +RG+    L   D  LP   C   +NIFHP DPV YR+E L+N     I PV I
Sbjct:   16 VAIPYSPVVAHWFYKRSVDTKFIWTPFSHYDSALLETSLN---------LDDSTLIIPVEGGRYDVNIKERTKTPVYWEG-----KAIEVRRCSWF----YKGVDSKYVPYTEDTAALLEAEYKRSAETG-----EWHQKIMLANGEQVVFHGPTVIVHFLPQQNADTWGASTQGSMRPRV--------VKRDLDDFTIEQGESQRVDHLLFMVHGIGSACDLKMRSVEEVVDDFRVIAQQLVQSHYKNSTDMGLVGRVEVLPISWHGHLHSEELGIDEKLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEF---NGGVSLAGHSLGSLILFDLLCHQEPLKESEEENKENPDQLPQKQSSQKVQLPTSDPLPKQ--------VSYAMGPEGTGQPVITYTQLIFHPKKF---------------FALGSPIGMFVTIRGIDKLGL---DFHLPT--CPGFYNIFHPFDPVAYRIEALVNPDMNGIRPVLI 469          
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Match: PAPLA1 (gene:FBgn0031990 transcript:FBtr0339673)

HSP 1 Score: 129.798 bits (325), Expect = 5.392e-30
Identity = 137/522 (26.25%), Postives = 225/522 (43.10%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK----LWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDS------EKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHL-NVKSLVVGGYHI--DWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQK--MKGGDITYQVSKIRAVCRKVTKKFFPLLEEAN--QRVEFLPVEWRKSLVLDGNTVD----LITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANF-PSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRI 1804
            + +P  P    WFYK +     +W PF  YDS  LET             +     I V G  Y+V++  R   P+YW       ++  + R +WF    ++ +DS      E  A  +E E+ +      S+ET +       QK+ L N + +V  G  +   +  Q +   +  S    +R R+        + R        + +   + HL+F++HGIG    +K   +   V   R + +++ +  +    +     RVE LP+ W   L  +   +D     IT      LRN  N T LD+L+Y+SP Y  +++ ++   LN +Y  +  R P F    G VS   HSLG+++L+D+L +  P K  E  E  + D   +     ++QL +   + K+  + +          E T +    + +  F P  F               F +GSP+ +F+ +RG+  + L  +D  LP   C   +NIFHP DPV YR+E L+N     I PV I
Sbjct: 1369 VAIPYSPVVAHWFYKRSVDTKFIWTPFSHYDSALLETSLN---------LDDSTLIIPVEGGRYDVNIKERTKTPVYWEG-----KAIEVRRCSWF----YKGVDSKYVPYTEDTAALLEAEYKR------SAETGE-----WHQKIMLANGEQVVFHGPTVIVHFLPQQNADTWGASTQGSMRPRV--------VKRDLDDFTIEQGESQRVDHLLFMVHGIGSACDLKMRSVEEVVDDFRVIAQQLVQSHYKNSTDMGLVGRVEVLPISWHGHLHSEELGIDEKLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEFN---GGVSLAGHSLGSLILFDLLCHQEPLKESEE-ENKNPDQLPQKQSSQKVQLPTSDPLPKQVSYAM--------GPEGTGQPVITYTQLIFHPKKF---------------FALGSPIGMFVTIRGI--DKLG-LDFHLP--TCPGFYNIFHPFDPVAYRIEALVNPDMNGIRPVLI 1821          
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Match: PAPLA1 (gene:FBgn0031990 transcript:FBtr0079641)

HSP 1 Score: 128.642 bits (322), Expect = 1.299e-29
Identity = 136/522 (26.05%), Postives = 224/522 (42.91%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK----LWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDS------EKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHL-NVKSLVVGGYHI--DWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQK--MKGGDITYQVSKIRAVCRKVTKKFFPLLEEAN--QRVEFLPVEWRKSLVLDGNTVD----LITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANF-PSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRI 1804
            + +P  P    WFYK +     +W PF  YDS  LET             +     I V G  Y+V++  R   P+YW       ++  + R +WF    ++ +DS      E  A  +E E+ +      S+ET +       QK+ L N + +V  G  +   +  Q +   +  S    +R R+        + R        + +   + HL+F++HGIG    +K   +   V   R + +++ +  +    +     RVE LP+ W   L  +   +D     IT      LRN  N T LD+L+Y+SP Y  +++ ++   LN +Y  +  R P F    G VS   HSLG+++L+D+L +  P K  E     + D   +     ++QL +   + K+  + +          E T +    + +  F P  F               F +GSP+ +F+ +RG+  + L  +D  LP   C   +NIFHP DPV YR+E L+N     I PV I
Sbjct: 1369 VAIPYSPVVAHWFYKRSVDTKFIWTPFSHYDSALLETSLN---------LDDSTLIIPVEGGRYDVNIKERTKTPVYWEG-----KAIEVRRCSWF----YKGVDSKYVPYTEDTAALLEAEYKR------SAETGE-----WHQKIMLANGEQVVFHGPTVIVHFLPQQNADTWGASTQGSMRPRV--------VKRDLDDFTIEQGESQRVDHLLFMVHGIGSACDLKMRSVEEVVDDFRVIAQQLVQSHYKNSTDMGLVGRVEVLPISWHGHLHSEELGIDEKLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEFN---GGVSLAGHSLGSLILFDLLCHQEPLKESEEENKENPDQLPQKQSSQKVQLPTSDPLPKQVSYAMG--------PEGTGQPVITYTQLIFHPKKF---------------FALGSPIGMFVTIRGI--DKLG-LDFHLP--TCPGFYNIFHPFDPVAYRIEALVNPDMNGIRPVLI 1822          
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Match: rdgB (gene:FBgn0003218 transcript:FBtr0301535)

HSP 1 Score: 59.3066 bits (142), Expect = 1.638e-8
Identity = 30/76 (39.47%), Postives = 43/76 (56.58%), Query Frame = 2
Query: 1601 NLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRI-----YPL 1813
            + F  GSPL+V LA R L     +     LP   C +V+N+FHP DP+  RLEPL++  ++ + PV +     YPL
Sbjct:  749 DFFMFGSPLSVVLAARKLHDAKAA-----LPRPNCHQVYNLFHPTDPIASRLEPLLSARFSILAPVNVPRYAKYPL 819          
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Match: ddhd1a (DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-111020-16])

HSP 1 Score: 414.461 bits (1064), Expect = 3.942e-131
Identity = 217/543 (39.96%), Postives = 328/543 (60.41%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTN-------------------QXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSET--ADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAK--IYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            ++  L PE++RWFYKE+K  W PF G+DSL +E  +R  T                    +   S ++  E + VRG LYEVDV ++  +P+YWN     QE  P++RG WF  A+W P++ ++ +  IEKEHL  +      +    D  A+ + +K    + S+ +   H+DWY  D V++Y+D+ +      +  +LG +K    G++L+RGY  EA ++DK P+ TH+VFVIHGIGQKM    I      +R   RK+ +K +   E+  + VEFLPVEWR  L LDG+TV+ ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLYS+FC+R+P FE  GGKVS I+HSLG V+ +DI+  W P +  + E+ + L+ ++   +S+E R  L  ++ + ++++H L              R Q +  + + P++F          K+EN FC+G PLAVFLALRG++P N    DHI+P+ +C+R+FNIFHP DPV YRLEPL+ + Y+ I PV+I+  +  N  PYD
Sbjct:   81 VVTELGPEEVRWFYKEDKKTWKPFMGHDSLNIEIMYRRFTQLNPGGSVNQERFGEDGAPLERRESVDAGVEAVCVRGGLYEVDVRSKECYPVYWNQ----QERIPVMRGQWFTDATWAPVEEDE-SELIEKEHLTCFRGQQIQDNFDTDALAKTVDRKD--AIHSVQLSRSHVDWYSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLDDKPPNTTHIVFVIHGIGQKMDKDRIIKNTGMLREAVRKMEEKHYS--EQTEEHVEFLPVEWRSKLALDGDTVESITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYSLFCSRNPQFEGDGGKVSIISHSLGCVITFDIMTGWDPVRFCLQEHHDQLEAEDSQWSSYEER-HLLEEVQLTRQRLHEL--------------RDQLHGLKESKPASFPTLKF-----KVENFFCMGCPLAVFLALRGIRPGNTGHQDHIMPKSICRRLFNIFHPTDPVAYRLEPLVLKHYSKIAPVQIHWCNTINPTPYD 594          
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Match: ddhd1a (DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-111020-16])

HSP 1 Score: 414.075 bits (1063), Expect = 1.448e-130
Identity = 217/543 (39.96%), Postives = 328/543 (60.41%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTN-------------------QXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSET--ADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAK--IYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            ++  L PE++RWFYKE+K  W PF G+DSL +E  +R  T                    +   S ++  E + VRG LYEVDV ++  +P+YWN     QE  P++RG WF  A+W P++ ++ +  IEKEHL  +      +    D  A+ + +K    + S+ +   H+DWY  D V++Y+D+ +      +  +LG +K    G++L+RGY  EA ++DK P+ TH+VFVIHGIGQKM    I      +R   RK+ +K +   E+  + VEFLPVEWR  L LDG+TV+ ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLYS+FC+R+P FE  GGKVS I+HSLG V+ +DI+  W P +  + E+ + L+ ++   +S+E R  L  ++ + ++++H L              R Q +  + + P++F          K+EN FC+G PLAVFLALRG++P N    DHI+P+ +C+R+FNIFHP DPV YRLEPL+ + Y+ I PV+I+  +  N  PYD
Sbjct:  116 VVTELGPEEVRWFYKEDKKTWKPFMGHDSLNIEIMYRRFTQLNPGGSVNQERFGEDGAPLERRESVDAGVEAVCVRGGLYEVDVRSKECYPVYWNQ----QERIPVMRGQWFTDATWAPVEEDE-SELIEKEHLTCFRGQQIQDNFDTDALAKTVDRKD--AIHSVQLSRSHVDWYSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLDDKPPNTTHIVFVIHGIGQKMDKDRIIKNTGMLREAVRKMEEKHYS--EQTEEHVEFLPVEWRSKLALDGDTVESITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYSLFCSRNPQFEGDGGKVSIISHSLGCVITFDIMTGWDPVRFCLQEHHDQLEAEDSQWSSYEER-HLLEEVQLTRQRLHEL--------------RDQLHGLKESKPASFPTLKF-----KVENFFCMGCPLAVFLALRGIRPGNTGHQDHIMPKSICRRLFNIFHPTDPVAYRLEPLVLKHYSKIAPVQIHWCNTINPTPYD 629          
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Match: ddhd1a (DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-111020-16])

HSP 1 Score: 403.675 bits (1036), Expect = 2.824e-126
Identity = 218/573 (38.05%), Postives = 330/573 (57.59%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTN-------------------QXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSET--ADGFAQQISQKLHLN------------------------------VKSLVVGGYHIDWYDQDSVFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAK--IYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            ++  L PE++RWFYKE+K  W PF G+DSL +E  +R  T                    +   S ++  E + VRG LYEVDV ++  +P+YWN     QE  P++RG WF  A+W P++ ++ +  IEKEHL  +      +    D  A+ + +K  L+                              + S+ +   H+DWY  D V++Y+D+ +      +  +LG +K    G++L+RGY  EA ++DK P+ TH+VFVIHGIGQKM    I      +R   RK+ +K +   E+  + VEFLPVEWR  L LDG+TV+ ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLYS+FC+R+P FE  GGKVS I+HSLG V+ +DI+  W P +  + E+ + L+ ++   +S+E R  L  ++ + ++++H L              R Q +  + + P++F          K+EN FC+G PLAVFLALRG++P N    DHI+P+ +C+R+FNIFHP DPV YRLEPL+ + Y+ I PV+I+  +  N  PYD
Sbjct:  116 VVTELGPEEVRWFYKEDKKTWKPFMGHDSLNIEIMYRRFTQLNPGGSVNQERFGEDGAPLERRESVDAGVEAVCVRGGLYEVDVRSKECYPVYWNQ----QERIPVMRGQWFTDATWAPVEEDE-SELIEKEHLTCFRGQQIQDNFDTDALAKTVDRKDVLSHFPPFYLPFLFKWSGYQTGAKSHKRKRCQAIHSVQLSRSHVDWYSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLDDKPPNTTHIVFVIHGIGQKMDKDRIIKNTGMLREAVRKMEEKHYS--EQTEEHVEFLPVEWRSKLALDGDTVESITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYSLFCSRNPQFEGDGGKVSIISHSLGCVITFDIMTGWDPVRFCLQEHHDQLEAEDSQWSSYEER-HLLEEVQLTRQRLHEL--------------RDQLHGLKESKPASFPTLKF-----KVENFFCMGCPLAVFLALRGIRPGNTGHQDHIMPKSICRRLFNIFHPTDPVAYRLEPLVLKHYSKIAPVQIHWCNTINPTPYD 661          
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Match: ddhd1a (DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-111020-16])

HSP 1 Score: 403.675 bits (1036), Expect = 2.824e-126
Identity = 218/573 (38.05%), Postives = 330/573 (57.59%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTN-------------------QXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSET--ADGFAQQISQKLHLN------------------------------VKSLVVGGYHIDWYDQDSVFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAK--IYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            ++  L PE++RWFYKE+K  W PF G+DSL +E  +R  T                    +   S ++  E + VRG LYEVDV ++  +P+YWN     QE  P++RG WF  A+W P++ ++ +  IEKEHL  +      +    D  A+ + +K  L+                              + S+ +   H+DWY  D V++Y+D+ +      +  +LG +K    G++L+RGY  EA ++DK P+ TH+VFVIHGIGQKM    I      +R   RK+ +K +   E+  + VEFLPVEWR  L LDG+TV+ ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLYS+FC+R+P FE  GGKVS I+HSLG V+ +DI+  W P +  + E+ + L+ ++   +S+E R  L  ++ + ++++H L              R Q +  + + P++F          K+EN FC+G PLAVFLALRG++P N    DHI+P+ +C+R+FNIFHP DPV YRLEPL+ + Y+ I PV+I+  +  N  PYD
Sbjct:  116 VVTELGPEEVRWFYKEDKKTWKPFMGHDSLNIEIMYRRFTQLNPGGSVNQERFGEDGAPLERRESVDAGVEAVCVRGGLYEVDVRSKECYPVYWNQ----QERIPVMRGQWFTDATWAPVEEDE-SELIEKEHLTCFRGQQIQDNFDTDALAKTVDRKDVLSHFPPFYLPFLFKWSGYQTGAKSHKRKRCQAIHSVQLSRSHVDWYSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLDDKPPNTTHIVFVIHGIGQKMDKDRIIKNTGMLREAVRKMEEKHYS--EQTEEHVEFLPVEWRSKLALDGDTVESITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYSLFCSRNPQFEGDGGKVSIISHSLGCVITFDIMTGWDPVRFCLQEHHDQLEAEDSQWSSYEER-HLLEEVQLTRQRLHEL--------------RDQLHGLKESKPASFPTLKF-----KVENFFCMGCPLAVFLALRGIRPGNTGHQDHIMPKSICRRLFNIFHPTDPVAYRLEPLVLKHYSKIAPVQIHWCNTINPTPYD 661          
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Match: ddhd1b (DDHD domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-040724-18])

HSP 1 Score: 370.163 bits (949), Expect = 2.596e-113
Identity = 195/464 (42.03%), Postives = 279/464 (60.13%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVD+  +  +P+YWN     Q+  P++RG WF   +W PL+ E  ++ IE EHL  +      +T D  A   +      + SL +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +ED  P+ TH+VFV+HGIGQKM  G I    S +R   RK+ +K F   +  N+ VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLY +FC R+P F  KG KVS ++HSLG V+ +DI+  W P + + + +  D    D +  E   QL  +L +   ++  LE         +     QT+  R +    F          K+EN FC+GSPLAVFLALRG++P +  T DHILP  +C+R+FNIFHP DPV YRLEPLI + Y+NI PV+I+  +  +  PYD
Sbjct:  234 RGGLYEVDIKGKSCYPVYWNQ----QDHIPVMRGQWFTDGTWLPLEEED-SDLIELEHLACFRGQQMKDTFDTEAVATTVDSKDAIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEAALEDTPPETTHIVFVVHGIGQKMDQGRIIRNTSMMRDAARKMEEKHFS--DRINEHVEFLPVEWRSKLALDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDEITRGLTKELNRLYMLFCERNPEFAEKG-KVSIVSHSLGCVITFDIMTGWDPVR-FVHEDVPDVMEADVSRQER--QLLEELRLTYLRIRDLE---------DRLQNFQTSSSRPSPALKF----------KVENFFCMGSPLAVFLALRGVRPGSGGTQDHILPTSICQRLFNIFHPTDPVAYRLEPLILKHYSNITPVQIHWYNTTSPTPYD 667          
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Match: DDHD1 (DDHD domain containing 1 [Source:NCBI gene;Acc:100493824])

HSP 1 Score: 425.246 bits (1092), Expect = 1.980e-134
Identity = 224/538 (41.64%), Postives = 323/538 (60.04%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXX-----------------RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLN--VKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPY 1837
            ++  L PE++RWFYKE+K  W PF GYDSLR+E  +R+L   +  +++    +                    R  LYEVDV     +P+YWN  D      P++RG WF   +WQPLD E+ +N IE++HL  +      +  D    +I++ +       SL +   H+DW++ D V++Y+D+     +  +  +LG +K    G++L+RGY  EA  EDK  DITH+VFV+HGIGQKM  G I    + +R   R++ +K FP        VEFLPVEWR  L LDG+TVD ITP++ +G+R+++NS+A+DI+YY+SP+YR E++  L+ ELNRLY++FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE  E  D D +  +  E    L  +L + K+++  LE+                  R     ++  N    K   K+EN FC+GSPLAVFLALRG++P N  T DHILP+ +C R+FNIFHPADPV YRLEPLI + Y NI PV+I+  +  N +PY
Sbjct:  137 VVTELSPEEVRWFYKEDKKTWKPFIGYDSLRIELAYRKLWELTAAAAKDQSGEEEELDVVTIGDFVKVEPVCVRSGLYEVDVNEGECYPVYWNQTD----KIPVMRGQWFIDGTWQPLDEEE-SNLIEQDHLTCF---RGQQMQDNLDTEITKPVDDKDASHSLKLSRSHVDWHNVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASYEDKPVDITHIVFVVHGIGQKMDQGRIIKNTATMRDTARRIEEKHFPHF--VTDHVEFLPVEWRSKLTLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYTLFCSRNPEFEEKGGKVSIVSHSLGCVITYDIMTGWNPGQLYEQQEDDDADVQGISYEEE--HLLRELYLTKQRLKELEV------------------RLHEVRASLSNAPALKF--KVENFFCMGSPLAVFLALRGIRPGNRGTQDHILPKAICNRLFNIFHPADPVAYRLEPLILKHYNNISPVQIHSSNTTNPLPY 642          
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Match: DDHD1 (DDHD domain containing 1 [Source:NCBI gene;Acc:100493824])

HSP 1 Score: 371.318 bits (952), Expect = 9.024e-117
Identity = 189/434 (43.55%), Postives = 272/434 (62.67%), Query Frame = 2
Query:  563 IRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLN--VKSLVVGGYHIDWYDQDSVFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPY 1837
            +RG WF   +WQPLD E+ +N IE++HL  +      +  D    +I++ +       SL +   H+DW++ D V++Y+D+ +      +  +LG +K    G++L+RGY  EA  EDK  DITH+VFV+HGIGQKM  G I    + +R   R++ +K FP        VEFLPVEWR  L LDG+TVD ITP++ +G+R+++NS+A+DI+YY+SP+YR E++  L+ ELNRLY++FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE  E  D D +  +  E    L  +L + K+++  LE+                  R     ++  N    K   K+EN FC+GSPLAVFLALRG++P N  T DHILP+ +C R+FNIFHPADPV YRLEPLI + Y NI PV+I+  +  N +PY
Sbjct:    1 MRGQWFIDGTWQPLDEEE-SNLIEQDHLTCF---RGQQMQDNLDTEITKPVDDKDASHSLKLSRSHVDWHNVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASYEDKPVDITHIVFVVHGIGQKMDQGRIIKNTATMRDTARRIEEKHFPHF--VTDHVEFLPVEWRSKLTLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYTLFCSRNPEFEEKGGKVSIVSHSLGCVITYDIMTGWNPGQLYEQQEDDDADVQGISYEEE--HLLRELYLTKQRLKELEV------------------RLHEVRASLSNAPALKF--KVENFFCMGSPLAVFLALRGIRPGNRGTQDHILPKAICNRLFNIFHPADPVAYRLEPLILKHYNNISPVQIHSSNTTNPLPY 406          
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Match: DDHD1 (DDHD domain containing 1 [Source:NCBI gene;Acc:100493824])

HSP 1 Score: 317.005 bits (811), Expect = 1.693e-95
Identity = 162/388 (41.75%), Postives = 238/388 (61.34%), Query Frame = 2
Query:  314 PLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXX-----------------RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLN--VKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDN 1396
            P  PE++RWFYKE+K  W PF GYDSLR+E  +R+L   +  +++    +                    R  LYEVDV     +P+YWN  D      P++RG WF   +WQPLD E+ +N IE++HL  +      +  D    +I++ +       SL +   H+DW++ D V++Y+D+     +  +  +LG +K    G++L+RGY  EA  EDK  DITH+VFV+HGIGQKM  G I    + +R   R++ +K FP        VEFLPVEWR  L LDG+TVD ITP++ +G+R+++NS+A+DI+YY+SP+YR E++  L+ ELNRLY++FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE  E  D +N
Sbjct:   22 PGGPEEVRWFYKEDKKTWKPFIGYDSLRIELAYRKLWELTAAAAKDQSGEEEELDVVTIGDFVKVEPVCVRSGLYEVDVNEGECYPVYWNQTD----KIPVMRGQWFIDGTWQPLDEEE-SNLIEQDHLTCF---RGQQMQDNLDTEITKPVDDKDASHSLKLSRSHVDWHNVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASYEDKPVDITHIVFVVHGIGQKMDQGRIIKNTATMRDTARRIEEKHFPHF--VTDHVEFLPVEWRSKLTLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYTLFCSRNPEFEEKGGKVSIVSHSLGCVITYDIMTGWNPGQLYEQQEDDDVEN 399          

HSP 2 Score: 120.168 bits (300), Expect = 2.384e-27
Identity = 52/81 (64.20%), Postives = 64/81 (79.01%), Query Frame = 2
Query: 1595 LENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPY 1837
            +EN FC+GSPLAVFLALRG++P N  T DHILP+ +C R+FNIFHPADPV YRLEPLI + Y NI PV+I+  +  N +PY
Sbjct:  397 VENFFCMGSPLAVFLALRGIRPGNRGTQDHILPKAICNRLFNIFHPADPVAYRLEPLILKHYNNISPVQIHSSNTTNPLPY 477          
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Match: DDHD1 (DDHD domain containing 1 [Source:NCBI gene;Acc:100493824])

HSP 1 Score: 317.775 bits (813), Expect = 1.675e-94
Identity = 162/398 (40.70%), Postives = 241/398 (60.55%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXX-----------------RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKL---------HLNVKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDN 1396
            ++  L PE++RWFYKE+K  W PF GYDSLR+E  +R+L   +  +++    +                    R  LYEVDV     +P+YWN  D      P++RG WF   +WQPLD E+ +N IE++HL  +      +  D    +I++ +           +  SL +   H+DW++ D V++Y+D+     +  +  +LG +K    G++L+RGY  EA  EDK  DITH+VFV+HGIGQKM  G I    + +R   R++ +K FP        VEFLPVEWR  L LDG+TVD ITP++ +G+R+++NS+A+DI+YY+SP+YR E++  L+ ELNRLY++FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE  E  D +N
Sbjct:  137 VVTELSPEEVRWFYKEDKKTWKPFIGYDSLRIELAYRKLWELTAAAAKDQSGEEEELDVVTIGDFVKVEPVCVRSGLYEVDVNEGECYPVYWNQTD----KIPVMRGQWFIDGTWQPLDEEE-SNLIEQDHLTCF---RGQQMQDNLDTEITKPVDDKDGEINSQASSHSLKLSRSHVDWHNVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASYEDKPVDITHIVFVVHGIGQKMDQGRIIKNTATMRDTARRIEEKHFPHF--VTDHVEFLPVEWRSKLTLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYTLFCSRNPEFEEKGGKVSIVSHSLGCVITYDIMTGWNPGQLYEQQEDDDVEN 524          

HSP 2 Score: 120.168 bits (300), Expect = 3.578e-27
Identity = 52/81 (64.20%), Postives = 64/81 (79.01%), Query Frame = 2
Query: 1595 LENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPY 1837
            +EN FC+GSPLAVFLALRG++P N  T DHILP+ +C R+FNIFHPADPV YRLEPLI + Y NI PV+I+  +  N +PY
Sbjct:  522 VENFFCMGSPLAVFLALRGIRPGNRGTQDHILPKAICNRLFNIFHPADPVAYRLEPLILKHYNNISPVQIHSSNTTNPLPY 602          
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Match: DDHD1 (DDHD domain containing 1 [Source:NCBI gene;Acc:100493824])

HSP 1 Score: 306.605 bits (784), Expect = 1.290e-90
Identity = 166/425 (39.06%), Postives = 244/425 (57.41%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXX-----------------RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKL-------HL----------------NVK-------------SLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDN 1396
            ++  L PE++RWFYKE+K  W PF GYDSLR+E  +R+L   +  +++    +                    R  LYEVDV     +P+YWN  D      P++RG WF   +WQPLD E+ +N IE++HL  +      +  D    +I++ +       HL                N K             SL +   H+DW++ D V++Y+D+     +  +  +LG +K    G++L+RGY  EA  EDK  DITH+VFV+HGIGQKM  G I    + +R   R++ +K FP        VEFLPVEWR  L LDG+TVD ITP++ +G+R+++NS+A+DI+YY+SP+YR E++  L+ ELNRLY++FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE  E  D +N
Sbjct:  137 VVTELSPEEVRWFYKEDKKTWKPFIGYDSLRIELAYRKLWELTAAAAKDQSGEEEELDVVTIGDFVKVEPVCVRSGLYEVDVNEGECYPVYWNQTD----KIPVMRGQWFIDGTWQPLDEEE-SNLIEQDHLTCF---RGQQMQDNLDTEITKPVDDKDVISHLPPFSLPFLFKWSGYKENTKAPCAKRKRCEASHSLKLSRSHVDWHNVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASYEDKPVDITHIVFVVHGIGQKMDQGRIIKNTATMRDTARRIEEKHFPHF--VTDHVEFLPVEWRSKLTLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYTLFCSRNPEFEEKGGKVSIVSHSLGCVITYDIMTGWNPGQLYEQQEDDDVEN 551          

HSP 2 Score: 119.013 bits (297), Expect = 8.577e-27
Identity = 52/81 (64.20%), Postives = 64/81 (79.01%), Query Frame = 2
Query: 1595 LENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPY 1837
            +EN FC+GSPLAVFLALRG++P N  T DHILP+ +C R+FNIFHPADPV YRLEPLI + Y NI PV+I+  +  N +PY
Sbjct:  549 VENFFCMGSPLAVFLALRGIRPGNRGTQDHILPKAICNRLFNIFHPADPVAYRLEPLILKHYNNISPVQIHSSNTTNPLPY 629          
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Match: Ddhd1 (DDHD domain containing 1 [Source:MGI Symbol;Acc:MGI:2150302])

HSP 1 Score: 383.645 bits (984), Expect = 2.213e-118
Identity = 198/468 (42.31%), Postives = 286/468 (61.11%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLN--VKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVDV     +P+YWN  D      P++RG WF   +WQPL+ E+ +N IE+EHL  +      +  + F  ++S+ L     V S  +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK    +H+VFV+HGIGQKM  G I    + +R   RK+ +K F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI++ W+P  +YE L   + +  D+   S+E R  L  +L + K ++  +E  +        +      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:  244 RGGLYEVDVTQGECYPVYWNQAD----KIPVMRGQWFIDGTWQPLEEEE-SNLIEQEHLSCF---RGQQMQENFDIEVSKSLDGKDAVHSFKLSRNHVDWHSMDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPGGLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLREIEDRLHGLKAPSISQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 680          
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Match: Ddhd1 (DDHD domain containing 1 [Source:MGI Symbol;Acc:MGI:2150302])

HSP 1 Score: 383.259 bits (983), Expect = 5.607e-118
Identity = 198/468 (42.31%), Postives = 286/468 (61.11%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLN--VKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVDV     +P+YWN  D      P++RG WF   +WQPL+ E+ +N IE+EHL  +      +  + F  ++S+ L     V S  +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK    +H+VFV+HGIGQKM  G I    + +R   RK+ +K F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI++ W+P  +YE L   + +  D+   S+E R  L  +L + K ++  +E  +        +      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:  244 RGGLYEVDVTQGECYPVYWNQAD----KIPVMRGQWFIDGTWQPLEEEE-SNLIEQEHLSCF---RGQQMQENFDIEVSKSLDGKDAVHSFKLSRNHVDWHSMDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPGGLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLREIEDRLHGLKAPSISQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 680          
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Match: Ddhd1 (DDHD domain containing 1 [Source:MGI Symbol;Acc:MGI:2150302])

HSP 1 Score: 374.015 bits (959), Expect = 4.054e-114
Identity = 200/499 (40.08%), Postives = 286/499 (57.31%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETAD----------------------------GF-----AQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVDV     +P+YWN  D      P++RG WF   +WQPL+ E+ +N IE+EHL  +      E  D                            G+     A  + +K    V S  +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK    +H+VFV+HGIGQKM  G I    + +R   RK+ +K F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI++ W+P  +YE L   + +  D+   S+E R  L  +L + K ++  +E  +        +      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:  244 RGGLYEVDVTQGECYPVYWNQAD----KIPVMRGQWFIDGTWQPLEEEE-SNLIEQEHLSCFRGQQMQENFDIEVSKSLDGKDVVYHLPPFSLPSLFKWRGYKESTDATGLKRKRSQAVHSFKLSRNHVDWHSMDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPGGLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLREIEDRLHGLKAPSISQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 714          

HSP 2 Score: 53.1434 bits (126), Expect = 1.946e-6
Identity = 23/39 (58.97%), Postives = 29/39 (74.36%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFREL 418
            ++  L PE++RWFYKE+K  W PF GYDSLR+E  FR L
Sbjct:  146 VVTELGPEEVRWFYKEDKKTWKPFIGYDSLRIELAFRTL 184          
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Match: Ddhd1 (DDHD domain containing 1 [Source:MGI Symbol;Acc:MGI:2150302])

HSP 1 Score: 139.813 bits (351), Expect = 9.305e-38
Identity = 68/150 (45.33%), Postives = 100/150 (66.67%), Query Frame = 2
Query:  779 VFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMI 1207
            V++Y+D+ +      +  +LG +K    G++L+RGY  EA +EDK    +H+VFV+HGIGQKM  G I    + +R   RK+ +K F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E +
Sbjct:    2 VYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDETL 148          
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Match: Ddhd2 (DDHD domain containing 2 [Source:MGI Symbol;Acc:MGI:1919358])

HSP 1 Score: 139.428 bits (350), Expect = 1.668e-33
Identity = 146/550 (26.55%), Postives = 235/550 (42.73%), Query Frame = 2
Query:  323 PEKIRWFY----KENKLWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGS-KLNRGY-KSEARIEDKLP---------DITHLVFVIHGIGQK--MKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQ--RVEFLPVEWRKSLVLDGNTVDL---ITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENR------------MQLFSDLNV-AKEKVHHLELLVLTKAEQE----------------NTNRGQTNFRRANFPSNFIN-------------GTLWKVLPKL----ENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLI 1768
            P    WFY       +LWIPF   DS +LE  +    +         +  +   G  Y+V +  R+ + +YW+ +        + R TWF                      K   DN     ++ F+Q +     L V +L      I+  +++ + ++        +   G ++ GS    +G  +S  R  + +P          I HLVFV+HGIG    ++   I   V+  R+V   + +  F   +E  Q  RVEFLPV W   L   G  +DL     P+ N+ LR+  N T LD+ +Y+SP Y   ++ ++  E+NR+Y++F  R+P F  KGG VS   HSLG+++L+DIL N   +     +  +D++    +S E+R            +QL   + V  KEKV    L + T  + +                +  +   +  R    ++ +N             G +    P+L    E  F  GSP+ +FL +RGL+      ID       CK  FNI+HP DPV YR+EP++
Sbjct:   39 PVSPHWFYCKVLDSKELWIPFNSEDSQQLEDAYGSGKD-------CNERIVPTDGGRYDVHLGERMRYAVYWDELPS-----EVRRCTWF---------------------YKGDKDNKYVPYSESFSQVLEDTYMLAV-TLDEWKKKIESPNREIIVLHNPKLMVHYQPIAGSDEWGSTSTEQGRPRSVKRGVENIPVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAQENEQIGRVEFLPVNWHSPLHSTGVDIDLQRITLPSINR-LRHFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDF--KGG-VSIAGHSLGSLILFDILTNQKNS-----IGDIDSEKGSLSSAEDRGDASTLEEDLKKLQLSEFVTVFEKEKVDREALALCTDRDLQEMGIPLGPRKKILNHFSARKNSVSINRPAMSASEVNISKENGDYLDVGIGQVSVKYPRLNYKPEIFFAFGSPIGMFLTVRGLR-----RIDPNYKFPTCKGFFNIYHPFDPVAYRIEPMV 540          
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Match: sp|O46606|DDHD1_BOVIN (Phospholipase DDHD1 OS=Bos taurus OX=9913 GN=DDHD1 PE=1 SV=1)

HSP 1 Score: 382.874 bits (982), Expect = 4.623e-117
Identity = 198/468 (42.31%), Postives = 286/468 (61.11%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLN--VKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVDV     +P+YWN  D      P++RG WF   +WQPL+ E+ +N IE+EHL  +      E+   F  ++S+ +     + S  +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK    TH+VFV+HGIGQKM  G I    + +R   RK+ ++ F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE L   + +  D+   S+E R  L  +L + K ++  +E  +        T      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:  263 RGGLYEVDVTQGECYPVYWNQSD----KIPVMRGQWFIDGTWQPLEEEE-SNLIEQEHLSRFRGQQMQES---FDIEVSKPIDGKDAIHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPNFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLREIEERLHGLKASSMTQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 699          
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8NEL9|DDHD1_HUMAN (Phospholipase DDHD1 OS=Homo sapiens OX=9606 GN=DDHD1 PE=1 SV=2)

HSP 1 Score: 382.489 bits (981), Expect = 1.068e-116
Identity = 198/468 (42.31%), Postives = 286/468 (61.11%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLN--VKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVDV     +P+YWN  D      P++RG WF   +WQPL+ E+ +N IE+EHL  +      +  + F  ++S+ +     V S  +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK    TH+VFV+HGIGQKM  G I    + +R   RK+ ++ F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI+  W+P ++YE L   + +  D+   S+E R  L  +L + K ++  +E  +        T      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:  260 RGGLYEVDVTQGECYPVYWNQAD----KIPVMRGQWFIDGTWQPLEEEE-SNLIEQEHLNCF---RGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLKEIEERLHGLKASSMTQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 696          
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q80YA3|DDHD1_MOUSE (Phospholipase DDHD1 OS=Mus musculus OX=10090 GN=Ddhd1 PE=1 SV=1)

HSP 1 Score: 318.546 bits (815), Expect = 1.444e-96
Identity = 161/365 (44.11%), Postives = 231/365 (63.29%), Query Frame = 2
Query:  773 DSVFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDK--TSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            D V++Y+D+ +      +  +LG +K    G++L+RGY  EA +EDK    +H+VFV+HGIGQKM  G I    + +R   RK+ +K F         VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E++  L+ ELNRLYS+FC+R+P FE KGGKVS ++HSLG V+ YDI++ W+P  +YE L   + +  D+   S+E R  L  +L + K ++  +E  +        +      F                   K+EN FC+GSPLAVFLALRG++P N  + DHILP ++C R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  N +PY+
Sbjct:    2 DEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHF---SNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPGGLYEQLLQKEEELPDERWMSYEER-HLLDELYITKRRLREIEDRLHGLKAPSISQTPALKF-------------------KVENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE 343          
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q80Y98|DDHD2_MOUSE (Phospholipase DDHD2 OS=Mus musculus OX=10090 GN=Ddhd2 PE=1 SV=3)

HSP 1 Score: 139.428 bits (350), Expect = 1.167e-32
Identity = 146/550 (26.55%), Postives = 235/550 (42.73%), Query Frame = 2
Query:  323 PEKIRWFY----KENKLWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGS-KLNRGY-KSEARIEDKLP---------DITHLVFVIHGIGQK--MKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQ--RVEFLPVEWRKSLVLDGNTVDL---ITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENR------------MQLFSDLNV-AKEKVHHLELLVLTKAEQE----------------NTNRGQTNFRRANFPSNFIN-------------GTLWKVLPKL----ENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLI 1768
            P    WFY       +LWIPF   DS +LE  +    +         +  +   G  Y+V +  R+ + +YW+ +        + R TWF                      K   DN     ++ F+Q +     L V +L      I+  +++ + ++        +   G ++ GS    +G  +S  R  + +P          I HLVFV+HGIG    ++   I   V+  R+V   + +  F   +E  Q  RVEFLPV W   L   G  +DL     P+ N+ LR+  N T LD+ +Y+SP Y   ++ ++  E+NR+Y++F  R+P F  KGG VS   HSLG+++L+DIL N   +     +  +D++    +S E+R            +QL   + V  KEKV    L + T  + +                +  +   +  R    ++ +N             G +    P+L    E  F  GSP+ +FL +RGL+      ID       CK  FNI+HP DPV YR+EP++
Sbjct:   39 PVSPHWFYCKVLDSKELWIPFNSEDSQQLEDAYGSGKD-------CNERIVPTDGGRYDVHLGERMRYAVYWDELPS-----EVRRCTWF---------------------YKGDKDNKYVPYSESFSQVLEDTYMLAV-TLDEWKKKIESPNREIIVLHNPKLMVHYQPIAGSDEWGSTSTEQGRPRSVKRGVENIPVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAQENEQIGRVEFLPVNWHSPLHSTGVDIDLQRITLPSINR-LRHFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDF--KGG-VSIAGHSLGSLILFDILTNQKNS-----IGDIDSEKGSLSSAEDRGDASTLEEDLKKLQLSEFVTVFEKEKVDREALALCTDRDLQEMGIPLGPRKKILNHFSARKNSVSINRPAMSASEVNISKENGDYLDVGIGQVSVKYPRLNYKPEIFFAFGSPIGMFLTVRGLR-----RIDPNYKFPTCKGFFNIYHPFDPVAYRIEPMV 540          
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Match: sp|O94830|DDHD2_HUMAN (Phospholipase DDHD2 OS=Homo sapiens OX=9606 GN=DDHD2 PE=1 SV=2)

HSP 1 Score: 138.658 bits (348), Expect = 2.512e-32
Identity = 154/556 (27.70%), Postives = 235/556 (42.27%), Query Frame = 2
Query:  323 PEKIRWFY----KENKLWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSK---------LNRGYKS-EARIEDKLP-DITHLVFVIHGIGQK--MKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQ--RVEFLPVEWRKSLVLDGNTVDL---ITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINW--SPAKIYEYLETLD--TDNKDKTSHEN---RMQLFSDLNV-AKEKVHHLELLVLTKAEQE----------------NTNRGQTNFRR--------ANFP--------SNFINGTLWKV--------LPKL----ENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLI 1768
            P    WFY       + WIPF   DS +LE  +                 +   G  Y+V +  R+ + +YW+ +     +  + R TWF                      K   DN     ++ F+Q + +   L V +L      ++  +++ + ++        +   G +  GS          + RG ++    I    P  I HLVFV+HGIG    ++   I   V+  R+V   + +  F   +E  Q  RVEFLPV W   L   G  VDL     P+ N+ LR+  N T LD+ +Y+SP Y   ++ ++  E+NR+Y++F  R+P F  KGG VS   HSLG+++L+DIL N   S   I    ++L+   D  D  + E    ++QL    ++  KEKV    L + T  + +                +T +     +R        AN P        SN  NG    V         P+L    E  F  GSP+ +FL +RGLK      ID       CK  FNI+HP DPV YR+EP++
Sbjct:   39 PVSPHWFYCKIIDSKETWIPFNSEDSQQLEEAY-------SSGKGCNGRVVPTDGGRYDVHLGERMRYAVYWDEL-----ASEVRRCTWF---------------------YKGDKDNKYVPYSESFSQVLEETYMLAV-TLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSDDWGSTPTEQGRPRTVKRGVENISVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVNDFRSVSLNLLQTHFKKAQENQQIGRVEFLPVNWHSPLHSTGVDVDLQRITLPSINR-LRHFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDF--KGG-VSIAGHSLGSLILFDILTNQKDSLGDIDSEKDSLNIVMDQGDTPTLEEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGIPLGPRKKILNYFSTRKNSMGIKRPAPQPASGANIPKESEFCSSSNTRNGDYLDVGIGQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRGLK-----RIDPNYRFPTCKGFFNIYHPFDPVAYRIEPMV 551          
BLAST of DDHD domain-containing protein vs. TrEMBL
Match: A0A1S3JQ63 (phospholipase DDHD1 OS=Lingula unguis OX=7574 GN=LOC106175188 PE=4 SV=1)

HSP 1 Score: 461.84 bits (1187), Expect = 9.828e-146
Identity = 243/527 (46.11%), Postives = 336/527 (63.76%), Query Frame = 2
Query:  302 NILLPLYPEKIRWFYKE--NKLWIPFCGYDSLRLETKFRELTN------QXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSAS----HFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEE-ANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYDS 1843
             I+  L P ++RWFY+E  +K W PF GYDSLR+E K+R L +      + V       + I VRG LYEVDV ++  +PIYW       E   I+RGTWF  +SWQPL+ E  A++IE EHL  +   + ++++  F     +K+   V ++    +H+DWY    V++Y+++ S      +R +LG+ K+GSKL+RGY  EA   DK PDITHLVFVIHGIGQKM  G I    +++R V  K+  ++FP +EE   QR EFLPVEWR SL LDG+ V+ ITP++ KGLR ++NS+A+DILYY+SP+YR E+   L+ ELNRLYSMF  R PYFE+ GGK+S +AHSLG V++YDI+  W+P ++Y+   T   + K   ++     L S L  A++KV+ LEL +++   ++N       FR                   LEN FCVGSPLAVFLALRG++P+   T DH+LP  LCKRVFN+FHPADP+ YRLEPLI + YA I P+R++  D PNK+PY++
Sbjct:   64 TIVTDLDPGEVRWFYREKGDKKWTPFTGYDSLRIEYKYRALLDNLHKPKRKVTEDGINVDLISVRGALYEVDVASKECYPIYWTG-----EPAEILRGTWFHESSWQPLE-EGYADQIETEHLAKFKSQSLAQSS--FYNPKGEKM--VVHNIKFKEFHMDWYSPLEVYLYSEATSSRFYRSVREKLGMQKIGSKLHRGYFDEAEGTDKPPDITHLVFVIHGIGQKMDTGSIVKCCAELREVAGKLKTRWFPHIEEDRQQRAEFLPVEWRSSLKLDGDIVESITPHKIKGLRTILNSSAMDILYYTSPLYRSEITQGLQTELNRLYSMFTDRHPYFESTGGKISIVAHSLGCVIMYDIITGWNPIQLYDQYVTNVIEEKSMEAN-GASPLISQLEEARKKVNSLELQLISLQSKQNVQTPTLKFR-------------------LENFFCVGSPLAVFLALRGMRPQENGTQDHLLPRSLCKRVFNLFHPADPIAYRLEPLILKHYATILPLRVHKHDAPNKVPYEN 560          
BLAST of DDHD domain-containing protein vs. TrEMBL
Match: A0A267G2H6 (DDHD domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026674g1 PE=4 SV=1)

HSP 1 Score: 458.373 bits (1178), Expect = 5.919e-143
Identity = 251/541 (46.40%), Postives = 340/541 (62.85%), Query Frame = 2
Query:  296 TSNILLPLYPEKIRWFYKEN--KLWIPFCGYDSLRLETKFREL----------TNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFP----IIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSET---------ADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYL--ETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPY 1837
             ++ +  L PE+IRWFY+E   K W+PF GYDSLRLE K REL             +  S +S  EKI+VRG L+E D+  R   PIYW+ +   + S      + RGTWFR   WQPL  E +A +IE EHL  +      E+           G     S K    + SL +   H++WYD   V +Y DS S FI  +LG+ + G++L RGYK EA++E+KL DITHLVFVIHGIGQKM+ G I      +R  C ++ KKFFP L+ ANQRVEFLPVEWR +L LDG+TVD ITP   +GLR ++NS+A+D+LYY+SP+YR E+   L+ EL+RLYSMFCAR PYFE  GGKVS I HSLG V+ YDI++ W+P ++Y+      L+  + D+   E   Q+  +L+ A++KV  LE  +L+ AE+++        + AN  +NF          +LENLFC+GSPLAVFLALRG++P+   T + I+P+ +  R++NI+HPADPV YRLEPLI + Y+ I+PV I+ +D  NK PY
Sbjct:   83 ANDCVAELRPEEIRWFYQEEGEKKWLPFNGYDSLRLECKHRELLCTAAGAAAAAPATGGSGDSHTEKILVRGGLFEADIAARSCRPIYWSEMRVNKMSVKQTAVLTRGTWFRENGWQPL-PEDLAAQIEAEHLAKFEGLRYEESPVCREGGSSGGGGGASGSSKSKEAIHSLRLTDCHVNWYDLRQVHLYQDSTSRFILQKLGVQRTGARLVRGYKDEAKVEEKLADITHLVFVIHGIGQKMRTGAIVKCAFDLRQTCERIKKKFFPDLDSANQRVEFLPVEWRSALTLDGDTVDSITPPNIRGLRTLLNSSAMDVLYYTSPLYRAEITHGLQTELSRLYSMFCARHPYFEPAGGKVSVIGHSLGCVITYDIVMGWNPMQLYDQFVHSYLNDKSNDR---EECQQVLKELDEARKKVTELEYSLLSMAEKQH--------KSANSCTNF----------RLENLFCLGSPLAVFLALRGIRPKGNGTQEDIVPKSIVNRIYNIYHPADPVAYRLEPLILKHYSTIQPVHIHRVDAMNKPPY 601          

HSP 2 Score: 70.4774 bits (171), Expect = 1.724e-8
Identity = 30/55 (54.55%), Postives = 43/55 (78.18%), Query Frame = 2
Query: 2537 TRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFMLTHIFGHLGEIGNPR 2701
            T L+ R+DY+L E RYESSY+SVLTSHT+YWS  ++ +F+++H+F   G IG P+
Sbjct:  841 TELEHRLDYQLREGRYESSYVSVLTSHTAYWSHEDIALFIMSHLFPDYGPIGIPK 895          
BLAST of DDHD domain-containing protein vs. TrEMBL
Match: A0A267DGF8 (DDHD domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000894g3 PE=4 SV=1)

HSP 1 Score: 442.965 bits (1138), Expect = 5.278e-141
Identity = 240/502 (47.81%), Postives = 323/502 (64.34%), Query Frame = 2
Query:  296 TSNILLPLYPEKIRWFYKEN--KLWIPFCGYDSLRLETKFREL----------TNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFP----IIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSET---------ADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAE-QENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNI 1723
             ++ +  L PE+IRWFY+E   K W+PF GYDSLRLE K REL             +  S +S  EKI+VRG L+E D+  R   PIYW+ +   + S      + RGTWFR   WQPL  E +A +IE EHL  +      E+           G +   S K    + SL +   H++WYD   V +Y DS S FI  +LG+ + G++L RGYK EA++E+KL DITHLVFVIHGIGQKM+ G I      +R  C ++ KKFFP L+ ANQRVEFLPVEWR +L LDG+TVD ITP   +GLR ++NS+A+D+LYY+SP+YR E+   L+ EL+RLYSMFCAR PYFE  GGKVS I HSLG V+ YDI++ W+P ++Y+       ++K     E + Q+  +L+ A++KV  LE  +L+ AE Q  +    TNFR+ANFPSNF +G LW+ LP+LENLFC+GSPLAVFLALRG++P+   T + I+P+ +  R++NI
Sbjct:   83 ANDCVAELRPEEIRWFYQEEGEKKWLPFNGYDSLRLECKHRELLCTAAGAAAEAPATGGSGDSHTEKILVRGGLFEADIAARSCRPIYWSEMRVNKMSVKQTAVLSRGTWFRENGWQPL-PEDLAAQIEAEHLAKFEGLRYEESPVCREGGSSVGGGSASGSSKSKEAIHSLRLTDCHVNWYDLRQVHLYQDSTSRFILQKLGVQRTGARLVRGYKDEAKVEEKLADITHLVFVIHGIGQKMRTGAIVKCAFDLRQTCERIKKKFFPDLDSANQRVEFLPVEWRSALTLDGDTVDSITPPNIRGLRTLLNSSAMDVLYYTSPLYRAEITHGLQTELSRLYSMFCARHPYFEPAGGKVSVIGHSLGCVITYDIVMGWNPMQLYDQFVHSYLNDKSNDREECQ-QVLKELDEARKKVTELEYSLLSMAEKQHKSANSCTNFRQANFPSNFKSGPLWRGLPQLENLFCLGSPLAVFLALRGIRPKGNGTQEDIVPKSIVNRIYNI 582          
BLAST of DDHD domain-containing protein vs. TrEMBL
Match: V3YZE1 (DDHD domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_133288 PE=4 SV=1)

HSP 1 Score: 430.254 bits (1105), Expect = 3.966e-136
Identity = 248/536 (46.27%), Postives = 337/536 (62.87%), Query Frame = 2
Query:  317 LYPEKIRWFYKE--NKLWIPFCGYDSLRLETKFRELT--NQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGG------------YHIDWYDQDSVFIYTDSAS-HFIR---HRLGLNKV--------GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYL-ETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPY 1837
            L PE+I WF+K+  +K W PF GYDSLR+E ++R L    Q+V     VKE+I+VRG LYEVDV ++  FPIYW+      +   I+RGTWF  ++WQPL+ E  AN++E EHL               A  I Q+L  +   ++V G            +HIDW     ++++++SAS  F+R   H LG  K         G++L+RGY  EA ++DK PDITHLVFVIHGIGQKM+ G I   V   +AV   +  K FP  + +NQR EFLPVEWR SL LDG+TVD ITPN+ KG+RN++NS+A+DILYY+SP YR E+  SL  ELNRLYS+FC R PYFE   GKVS +AHSLG+V+ YDI+  W P K+Y+ L  ++  D +++ S     +L  +L+ A+++V+ LE L+ +  E++N+           F  NF           +ENLFC+GSPLAVFLALRGL+P+   T++HILP   CKR+FNI+HP+DPV YRLEPL+ + YA I P+ I+  D  +K PY
Sbjct:   43 LRPEEINWFFKQEGDKKWTPFIGYDSLRIECRYRALAFGPQAVGEDIDVKERILVRGGLYEVDVDSKQCFPIYWSG-----DVSTILRGTWFHDSTWQPLE-EDYANQLETEHL---------------ANFIGQRLE-DAPPIIVKGPRPVIHNIRFHEFHIDWNSASEIYLFSESASSKFMRKVSHSLGWQKCDLVFIFSAGNRLHRGYCYEAVMDDKPPDITHLVFVIHGIGQKMETGSI---VRCCKAV-NHLKCKLFPKFDSSNQRAEFLPVEWRSSLKLDGDTVDNITPNKMKGVRNILNSSAMDILYYTSPAYRTEITNSLEHELNRLYSLFCQRHPYFEANNGKVSILAHSLGSVITYDIITGWKPMKMYDQLVNSVINDEREQAS--GSKELLGELDKARKRVNELEELLTSVQERQNS----------TFKLNF----------NIENLFCIGSPLAVFLALRGLRPQGTGTLEHILPTDSCKRLFNIYHPSDPVAYRLEPLVLKHYATIMPLPIHHYDSRHKTPY 530          
BLAST of DDHD domain-containing protein vs. TrEMBL
Match: A0A0L8GHQ7 (DDHD domain-containing protein (Fragment) OS=Octopus bimaculoides OX=37653 GN=OCBIM_22033258mg PE=4 SV=1)

HSP 1 Score: 425.631 bits (1093), Expect = 1.542e-132
Identity = 244/588 (41.50%), Postives = 362/588 (61.56%), Query Frame = 2
Query:  299 SNILLPLYPEKIRWFYKE--NKLWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHL-KLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSA-SHFIR---HRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTID-----HILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPY-DSSGFDETSVVDIVITRDSLRPDKPVIDEFSQKST-SEGITYSLPKSSHHTLAGKLVKLFYK 2020
            S I+  L+PE++RW Y+    K W PF GYDSLR+E ++REL+  S +S + +K+ IVVRG LYEVDV+ R  +P++W       ++  ++RG WF   +WQPL+ E  + +IE +HL K  G     + ++    ++++++   +  +     H++W +   V++++DS  S  +R     LG  K G+KL RGY +EAR++DK PDITHLVFV+HGIGQKM  G+I  + +++R    ++ KK FP L+++NQRVEFLPVEWR SL LDG+TV+LITP+  KGLR ++NS+A+DILYY+SP+YR E+   L+ E+NRLYS+FC R+PYF + GGK+S  AHSLGAV+ YDI+ +W+P K+Y+       D K +   ++   L +D++ A+ +V  +E  + +  E++        FR                   +ENLFC+GSPLAVFL LRG+    L   D     +++P  LC R+FNI+HPADP+ YR+EPLI + YA+I PV I   D P K PY + SG   TS  D ++   S    +  I    + ST +E  + SLPK+  ++L    + L  K
Sbjct:  132 SEIIEELHPEEVRWMYRHAGKKKWTPFIGYDSLRIEFRYRELS-VSSLSEDKLKDMIVVRGGLYEVDVVARKCYPLFWTG-----DTADVLRGIWFYDDTWQPLE-EDTSIRIESDHLGKFLGKKYPCDFSETVNLKVARQV---IHHIAFSDCHVEWRNATEVYMFSDSTPSKIVRSVSQTLGFQKSGTKLCRGYCNEARMDDKPPDITHLVFVVHGIGQKMDTGNIIKRCNELRESIERLKKKNFPNLDQSNQRVEFLPVEWRSSLQLDGDTVELITPHSVKGLRTILNSSAMDILYYTSPLYRSEITHGLQSEINRLYSVFCLRNPYFISAGGKISIAAHSLGAVITYDIITSWNPIKLYDQFVASLIDEK-REQLQDSTHLLTDMDSARARVSEIESQLSSLQEKQQKGSQALKFR-------------------VENLFCLGSPLAVFLTLRGVP---LHGCDNNGQPNVIPSHLCHRLFNIYHPADPIAYRIEPLIYKHYASILPVDIQRFDAPLKRPYSECSGRGSTS--DTLVDSSS----EHSIASIPESSTETEVESSSLPKTIGYSLGNMFLTLIKK 680          
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Match: ddhd1b (DDHD domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-040724-18])

HSP 1 Score: 379.793 bits (974), Expect = 7.555e-118
Identity = 214/570 (37.54%), Postives = 315/570 (55.26%), Query Frame = 2
Query:  299 SNILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTN-------------------------QXXXXXXXXXXXXXXRGDLYEVDVLN----------RIG-----------FPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIY--EYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
              ++  L PE++RWFYKE+K  W PF G+DSL++E  +R+L                           +             V G   E+DV +          R G           +P+YWN     QE  P++RG WF   +W PL+ E  ++ IE EHL  +  +   +T +  A   +      + SL +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA  ED  P  TH+VFV+HGIGQKM  G I    S +R   RK+ +K F   +   + VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLY++FC+R+P FE K GKVS ++HSLG V+ +DI+  W P + +  E  + ++T+ + +   E R  L  +L++ + ++  LE         +     + +  R + P  F          K+EN FC+GSPLAVFLALRG++P N  T DHILP  +C+R+ NIFHP DPV YRLEPLI + Y+NI PV+I+  +  +  PYD
Sbjct:   83 GEVVTELGPEEVRWFYKEDKRTWKPFVGHDSLQIELTYRKLCELNPGKASEQDEWEELGGSGGDSEGVEGQKGQTEASVSKEVAGPAEEIDVDSIDIGVEAVCVRGGLYEVDVKEKESYPVYWNQ----QERIPVMRGQWFTDGTWLPLEEED-SDLIELEHLSCFRGHQMKDTFETEAVTTAVDSKDAIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEAAPEDTPPAATHIVFVVHGIGQKMDQGRIIRNTSMMRDAARKMEEKHFS--DRTTEHVEFLPVEWRSKLSLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDEITRGLTKELNRLYTLFCSRNPEFEEK-GKVSIVSHSLGCVITFDIMTGWDPVRFHHQEAPDAMETEQRRRGCEEQR--LLEELHLTRMRLRDLE---------DQFQGLKMSSSRTSPPLKF----------KVENFFCMGSPLAVFLALRGIRPGNNGTQDHILPRSICQRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSSPTPYD 623          
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Match: ddhd1a (phospholipase DDHD1 [Source:NCBI gene;Acc:103023862])

HSP 1 Score: 370.548 bits (950), Expect = 1.136e-113
Identity = 197/470 (41.91%), Postives = 285/470 (60.64%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKL---HLNVKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKA---EQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LY+VDV     +P+YWN     Q+  P++RG WF   +W P++ ++ ++ IE+EHL  +      +  D F   +  K       + SL +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK P  TH+VFV+HGIGQKM    I      +R   RK+ +K F   +   + VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLY++FC+R+P FE KGGKVS I+HSLG V+ YDI+  W P + +  LE  + D       E  M+  S      E+ H LE + LT+    E E+  +G    +    P+         +  K+EN FC+GSPLAVFLALRG++P +    DHI+P+ +CKR+FNIFHP DPV YRLEPL+ + Y+NI PV+I+  +  +  PYD
Sbjct:  253 RGGLYQVDVREMECYPVYWNQ----QDRIPVMRGQWFIDGTWMPMEEDE-SDLIEREHLTSF---RGQQMQDSFENDVVVKTVDTKDAIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLEDKPPLTTHIVFVVHGIGQKMDKDRIIKNTGMLREAVRKMEEKHF--ADHTEEHVEFLPVEWRSKLALDGDTVDSITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYALFCSRNPEFEEKGGKVSIISHSLGCVIAYDIMTGWDPVR-FCLLEQQEPD-------EEEMRWMS-----YEERHLLEQVHLTRQRLRELEDKLQGLEASKPLQLPA---------LKFKVENYFCMGSPLAVFLALRGIRPGSTGYQDHIMPKSICKRLFNIFHPTDPVAYRLEPLVLKHYSNIAPVQIHWCNTTSPTPYD 690          
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Match: ddhd1a (phospholipase DDHD1 [Source:NCBI gene;Acc:103023862])

HSP 1 Score: 363.614 bits (932), Expect = 1.130e-110
Identity = 200/499 (40.08%), Postives = 289/499 (57.92%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNN------------SSETADGFAQ---------------QISQKLHLN-----VKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKA---EQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LY+VDV     +P+YWN     Q+  P++RG WF   +W P++ ++ ++ IE+EHL  +                + +T D  +                Q S K H       + SL +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK P  TH+VFV+HGIGQKM    I      +R   RK+ +K F   +   + VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLY++FC+R+P FE KGGKVS I+HSLG V+ YDI+  W P + +  LE  + D       E  M+  S      E+ H LE + LT+    E E+  +G    +    P+         +  K+EN FC+GSPLAVFLALRG++P +    DHI+P+ +CKR+FNIFHP DPV YRLEPL+ + Y+NI PV+I+  +  +  PYD
Sbjct:  253 RGGLYQVDVREMECYPVYWNQ----QDRIPVMRGQWFIDGTWMPMEEDE-SDLIEREHLTSFRGQQMQDSFENDVVVKTVDTKDALSHFPPFYLPFLFKWSGYQTSAKSHKRKRCQAIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLEDKPPLTTHIVFVVHGIGQKMDKDRIIKNTGMLREAVRKMEEKHF--ADHTEEHVEFLPVEWRSKLALDGDTVDSITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYALFCSRNPEFEEKGGKVSIISHSLGCVIAYDIMTGWDPVR-FCLLEQQEPD-------EEEMRWMS-----YEERHLLEQVHLTRQRLRELEDKLQGLEASKPLQLPA---------LKFKVENYFCMGSPLAVFLALRGIRPGSTGYQDHIMPKSICKRLFNIFHPTDPVAYRLEPLVLKHYSNIAPVQIHWCNTTSPTPYD 722          
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Match: ddhd1a (phospholipase DDHD1 [Source:NCBI gene;Acc:103023862])

HSP 1 Score: 344.354 bits (882), Expect = 2.132e-104
Identity = 200/540 (37.04%), Postives = 298/540 (55.19%), Query Frame = 2
Query:  305 ILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELT-----------NQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHL------NVKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKA---EQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            ++  L  E++RWFYKE+K  W PF G+DSL +E  +R+             N+     +      +     +  +V++R+G          G  +  +  G    V + +      +   I  E + + G         G  Q   +++         + SL +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA +EDK P  TH+VFV+HGIGQKM    I      +R   RK+ +K F   +   + VEFLPVEWR  L LDG+TVD ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLY++FC+R+P FE KGGKVS I+HSLG V+ YDI+  W P + +  LE  + D       E  M+  S      E+ H LE + LT+    E E+  +G    +    P+         +  K+EN FC+GSPLAVFLALRG++P +    DHI+P+ +CKR+FNIFHP DPV YRLEPL+ + Y+NI PV+I+  +  +  PYD
Sbjct:  133 VVTELGAEELRWFYKEDKKTWKPFAGHDSLNIELMYRKFCELNPVELDQDHNEDQHQDQEGASAALSEEGKHAAEVMDRVG------TCGPGSAAGQVEEGA--SVEAPESAGESDVDVSISVEAVCVRG---------GLYQVDVREMECYPVYWNPIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASLEDKPPLTTHIVFVVHGIGQKMDKDRIIKNTGMLREAVRKMEEKHF--ADHTEEHVEFLPVEWRSKLALDGDTVDSITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYALFCSRNPEFEEKGGKVSIISHSLGCVIAYDIMTGWDPVR-FCLLEQQEPD-------EEEMRWMS-----YEERHLLEQVHLTRQRLRELEDKLQGLEASKPLQLPA---------LKFKVENYFCMGSPLAVFLALRGIRPGSTGYQDHIMPKSICKRLFNIFHPTDPVAYRLEPLVLKHYSNIAPVQIHWCNTTSPTPYD 631          
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Match: sec23ip (SEC23 interacting protein [Source:NCBI gene;Acc:103028985])

HSP 1 Score: 121.709 bits (304), Expect = 1.246e-27
Identity = 104/370 (28.11%), Postives = 164/370 (44.32%), Query Frame = 2
Query:  302 NILLPLYPEKIRWFY----KENKLWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVAS----WQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKS------EARIEDKLPDITHLVFVIHGIGQ--KMKGGDITYQVSKIRAVCRKVTKKFFPLLEEAN--QRVEFLPVEWRKSLVLDGNTVDL----ITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILIN 1345
            N+  P+ P    WFY    +  K+W+PF   DSLRLE  F  +                  G  Y+V + +R    +YW      +E   + R TWF        + P  SE+ ++K+E E+ K    N           Q  ++L          G  I  ++   +  +  SA   +    G  + G    R  K       +   + ++P + HLVF++HGIG    ++   +   V   R V  K+ +  F   ++     RVEFLPV W  +L  D   VD     IT      LR+  N T LD+L+Y+SP Y   ++ ++  E+NRL+++F  R+P F+   G VS   HSLG+++L+D+L N
Sbjct:  245 NVYEPVQP---HWFYCKQVEAKKVWLPFSILDSLRLEETFNSIQPDPENVIICTD------GGRYDVQLYDRTRTSVYWE-----EEPTEVRRCTWFYKGDADSRFIPY-SEEFSDKLEAEYKKAVSTN-----------QWHRRLEFP------SGETIVMHNPKVIVQFQPSA---MPDEWGTTQDGQTRPRVVKRGVDDDHDEVPDGEMPQVDHLVFMVHGIGPVCDLRFRSMVECVDDFRTVSLKLLQSHFKKAQDERIISRVEFLPVHWHTALHGDATGVDRRIKKITLPSTGRLRHFTNETLLDVLFYNSPTYCQTIMDTVASEINRLHALFMQRNPDFK---GAVSVAGHSLGSLILFDLLSN 576          

HSP 2 Score: 56.225 bits (134), Expect = 1.565e-7
Identity = 27/56 (48.21%), Postives = 38/56 (67.86%), Query Frame = 2
Query: 1601 NLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLI 1768
            N F +GSP+ +FL +RG+  E +   ++ LP   CK  FNI+HP DPV YR+EP+I
Sbjct:  756 NFFALGSPIGMFLTVRGV--ERIEE-NYRLP--TCKGFFNIYHPLDPVAYRIEPMI 806          
BLAST of DDHD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010367.1 (pep scaffold:Pmarinus_7.0:GL490372:1378:4627:-1 gene:ENSPMAG00000009389.1 transcript:ENSPMAT00000010367.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 110.923 bits (276), Expect = 5.102e-28
Identity = 50/91 (54.95%), Postives = 67/91 (73.63%), Query Frame = 2
Query: 1571 TLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYDS 1843
            T W    K+EN FC+GSPLAVFLALRG++P +  +  HILP+ +C+R+FNIFHP DPV YRLEPLI + Y+ I+PV+I+     ++  YDS
Sbjct:    2 TSWMSGVKVENFFCMGSPLAVFLALRGVRPGSSGSPHHILPKSVCRRLFNIFHPTDPVAYRLEPLILRHYSAIQPVQIHWSSAVSRPRYDS 92          
BLAST of DDHD domain-containing protein vs. Ensembl Yeast
Match: DDL1 (DDHD domain-containing phospholipase A1; mitochondrial matrix enzyme with sn-1-specific activity, hydrolyzing cardiolipin, PE, PC, PG and PA; implicated in remodeling of mitochondrial phospholipids; antagonistically regulated by Aft1p and Aft2p; in humans, mutations in DDHD1 and DDHD2 genes cause specific types of hereditary spastic paraplegia, while DDL1-defective yeast share similar phenotypes such as mitochondrial dysfunction and defects in lipid metabolism [Source:SGD;Acc:S000005548])

HSP 1 Score: 74.3294 bits (181), Expect = 4.432e-14
Identity = 59/203 (29.06%), Postives = 96/203 (47.29%), Query Frame = 2
Query:  839 VGSKLNRGYKSEA---RIEDKLPDITHLVFVIHGIGQ----KMKGGDITYQVSKIRAVCRKVTKKFFPLLE-------EANQRVEFLPVEWRKSLVL------------DGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYE 1369
              SK+  G  S A   +I     D+ +L+  +HGIGQ    K +  +  + V+ +R+  +K+      L         ++N  V+ LP+ WR S+              D  T+  +T N    LR ++    LDIL Y  P Y+  ++  +  +LN+ Y +F   +P F+   GKV  + HSLG+++L+DIL   S  K YE
Sbjct:  322 ASSKIEDGKNSGASDRQIRSNRRDVDNLILCVHGIGQTLGKKYEYVNFAHTVNLLRSNMKKIYNNSEKLQSLNTAPDYKSNCNVQVLPITWRHSISFQTDAKEENIENPDLPTLSQVTVNGVLPLRKLLADGLLDILLYVEPYYQDMILQQVTSQLNKTYRIFKEFNPEFD---GKVHLVGHSLGSMILFDIL---SKQKKYE 518          

HSP 2 Score: 52.373 bits (124), Expect = 3.382e-7
Identity = 24/73 (32.88%), Postives = 46/73 (63.01%), Query Frame = 2
Query: 1592 KLENLFCVGSPLAVFLALR----GLKPENLSTIDHILPEQ--LCKRVFNIFHPADPVVYRLEPLINQTYANIE 1792
            +++NLF +GSP+ +   ++    G +PE  + ++  L  Q   CK ++N++H  DP+ YR+EPL+++  A+ E
Sbjct:  522 QVDNLFFIGSPIGLLKLIQRTKIGDRPEFPNDLERKLTVQRPQCKDIYNVYHVCDPISYRMEPLVSKEMAHYE 594          
BLAST of DDHD domain-containing protein vs. Ensembl Nematostella
Match: EDO40974 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5H0])

HSP 1 Score: 288.5 bits (737), Expect = 2.392e-87
Identity = 157/365 (43.01%), Postives = 223/365 (61.10%), Query Frame = 2
Query:  734 LVVGGYHIDWYDQDSVFIYTDS-ASHFIRH---RLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLD 1816
            L + GY+++W D   V++Y D   S  IR    ++GL   G +++RGY ++A  ED  P+I+HLVFVIHGIGQ +   +I    +  R+   KV +K  P      QRVEF PVEWR SL LD   +D ITP    GLR V+N T +DI+YY+SP YR E+I  LR ELNRLYS+FC R+P F+ K GKVS IAHSLG+V++YDIL  W            DT+ +  +  E     F  L  +   + +LE  + ++ E +   RG+         S   +   + +  K+ENLF VGSPLAVFL LRGL+P++    DH+LP+ +CK++ NI+HPADPV YR+EPLI++ Y+++ P++++  D
Sbjct:    4 LQLKGYYVEWKDVTDVWLYWDDIKSRIIRGVGTKIGLGSQGVQIHRGYHTDAVPEDCPPEISHLVFVIHGIGQLLHMSNIVKSATDFRSSAEKVHEKNIPGFPRG-QRVEFFPVEWRSSLKLDDGAIDAITPASVSGLRKVLNITMMDIMYYTSPFYRYEIISGLREELNRLYSLFCERNPSFQAKQGKVSIIAHSLGSVIMYDILSLW------------DTEIRHLSDQEKAGTGF--LTESFSFLRNLEAKLKSQIEFDQNRRGENG-------STAEDVCQYALKFKVENLFSVGSPLAVFLTLRGLRPQD-DVEDHVLPKSVCKKMLNIYHPADPVAYRMEPLISEEYSSVPPIQLHRFD 345          
BLAST of DDHD domain-containing protein vs. Ensembl Nematostella
Match: EDO37134 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGQ9])

HSP 1 Score: 109.383 bits (272), Expect = 1.872e-24
Identity = 102/364 (28.02%), Postives = 169/364 (46.43%), Query Frame = 2
Query:  323 PEKIRWFY-KENKLWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIR-GTWF-------RVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVV---GGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPD-----ITHLVFVIHGIG--QKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQ--RVEFLPVEWRKSLVLDGNTVD----LITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDIL 1339
            P +  WFY KEN++W+PF   DS  LE +F + T +      +        G  Y+V+V  R+   +YW      +E   ++R  TWF       ++  ++    E++A  +E E    Y     ++         S+ + L+  +++V        DW  +DS +          R ++        + RG    A IE+ + D     I HLVFVIHGIG    ++  +I   +  +R V   +  +    L +     R+E+LPV+W   L  D N VD     I+      LR+  NST LDIL+Y+SP Y   ++ ++  E+  L ++F  R+P F+   G++S   HSLG+ +++DIL
Sbjct:   19 PVRPHWFYMKENRVWMPFSHIDSEALEHEFSKPTTKEDRIVPTD-------GGRYDVNVDERVRRAVYW------EEDVSVVRRCTWFFKGDGGVKLVPYK----EEMAATLEAE---FYSAVRQNQWPRKIVISDSEYILLHNTNVMVHFQTCGPTDWSGEDSGW----------RPKV--------VRRGV---ADIEEDIEDGEGHQIDHLVFVIHGIGPIADLRFRNIIECIDDLRMVTLSMLNEHHQELAKGRTIGRIEYLPVQWHDKLHNDSNGVDERLHSISLKSISKLRDFTNSTLLDILFYTSPTYCQTIVDTVGSEMTNLLALFRKRNPSFK---GQISVCGHSLGSSIMFDIL 338          

HSP 2 Score: 65.4698 bits (158), Expect = 7.427e-11
Identity = 30/70 (42.86%), Postives = 45/70 (64.29%), Query Frame = 2
Query: 1604 LFCVGSPLAVFLALRGLKPENLSTIDHILPE---QLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRI 1804
            LF +GSP+ +F+ +RG        +D + P+     C++VFNIFHP DPV YRLEPL++ T+   +P+ I
Sbjct:  514 LFALGSPIGMFMTVRG--------VDQVGPDFKLPTCQKVFNIFHPFDPVAYRLEPLVDSTFVK-DPIMI 574          
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Match: ddhd1b (phospholipase DDHD1 [Source:NCBI gene;Acc:101171796])

HSP 1 Score: 376.326 bits (965), Expect = 9.027e-117
Identity = 219/538 (40.71%), Postives = 306/538 (56.88%), Query Frame = 2
Query:  278 SYSESKTSNILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTNQ--------------------XXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTD-NKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRI 1804
            S S      I+  L PE+IRWFYKE+K  W PF G DSL++E  +R  T Q                        S+   E + VRG LYEV +  +   P+YWN     QES P++RG WF   +W PL+ E  +N IE EHL  +      + ++      +      V SL +   H+DW+  D V++Y+D+ +      +  +LG +K    G++L RGY  EA  E+   + TH+VFV+HGIGQKM  G I    S +R   RK+ ++ FP  +   + VEFLPVEWR  L LDG+TVD ITP++ +G+R+++NS+A+DI+YY+SP+YR E+   L  ELNRLYS+FC+R+P FE K GKVS +AHSLG V+ +DI+  W P + + + + LD +  K +   E   QL             L +L L   + E+  RG         P+         +  K+EN FC+GSPLAVFLALRG++P N +  DHIL   +CKR+FN+FHP DPV YRLEPLI + Y+NI PV+I
Sbjct:   97 SNSSRHRGEIVTELGPEEIRWFYKEDKRTWKPFAGTDSLKIERLYRRRTEQLDPGSDPAGGDGEQNPVPEEVKSPSDVKAEAVCVRGGLYEVHIREKECCPVYWNQ----QESIPVMRGQWFVDGTWLPLEEED-SNPIEMEHLSHFRGQQMRDVSEVETAPSTVDSKDAVYSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLRRGYFEEAVPEETPSETTHIVFVVHGIGQKMDQGRIIRNTSMMRDAARKMEERHFP--DRTTEHVEFLPVEWRSKLYLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDEITRGLTQELNRLYSLFCSRNPDFE-KNGKVSIVAHSLGCVITFDIMTGWDPVR-FHHQQMLDPEKTKIRWPSEEERQL----------QEQLRVLRLRLRDLEDQFRGLQTSSSVAVPA---------LKFKVENFFCMGSPLAVFLALRGIRPGNNTMQDHILSTSICKRLFNLFHPTDPVAYRLEPLILKHYSNIAPVQI 606          
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Match: ddhd1b (phospholipase DDHD1 [Source:NCBI gene;Acc:101171796])

HSP 1 Score: 375.941 bits (964), Expect = 1.828e-116
Identity = 219/538 (40.71%), Postives = 306/538 (56.88%), Query Frame = 2
Query:  278 SYSESKTSNILLPLYPEKIRWFYKENK-LWIPFCGYDSLRLETKFRELTNQ--------------------XXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTD-NKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRI 1804
            S S      I+  L PE+IRWFYKE+K  W PF G DSL++E  +R  T Q                        S+   E + VRG LYEV +  +   P+YWN     QES P++RG WF   +W PL+ E  +N IE EHL  +      + ++      +      V SL +   H+DW+  D V++Y+D+ +      +  +LG +K    G++L RGY  EA  E+   + TH+VFV+HGIGQKM  G I    S +R   RK+ ++ FP  +   + VEFLPVEWR  L LDG+TVD ITP++ +G+R+++NS+A+DI+YY+SP+YR E+   L  ELNRLYS+FC+R+P FE K GKVS +AHSLG V+ +DI+  W P + + + + LD +  K +   E   QL             L +L L   + E+  RG         P+         +  K+EN FC+GSPLAVFLALRG++P N +  DHIL   +CKR+FN+FHP DPV YRLEPLI + Y+NI PV+I
Sbjct:   97 SNSSRHRGEIVTELGPEEIRWFYKEDKRTWKPFAGTDSLKIERLYRRRTEQLDPGSDPAGGDGEQNPVPEEVKSPSDVKAEAVCVRGGLYEVHIREKECCPVYWNQ----QESIPVMRGQWFVDGTWLPLEEED-SNPIEMEHLSHFRGQQMRDVSEVETAPSTVDSKDAVYSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLRRGYFEEAVPEETPSETTHIVFVVHGIGQKMDQGRIIRNTSMMRDAARKMEERHFP--DRTTEHVEFLPVEWRSKLYLDGDTVDSITPDKVRGIRDMLNSSAMDIMYYTSPLYRDEITRGLTQELNRLYSLFCSRNPDFE-KNGKVSIVAHSLGCVITFDIMTGWDPVR-FHHQQMLDPEKTKIRWPSEEERQL----------QEQLRVLRLRLRDLEDQFRGLQTSSSVAVPA---------LKFKVENFFCMGSPLAVFLALRGIRPGNNTMQDHILSTSICKRLFNLFHPTDPVAYRLEPLILKHYSNIAPVQI 606          
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Match: ddhd1a (phospholipase DDHD1 [Source:NCBI gene;Acc:101163939])

HSP 1 Score: 349.362 bits (895), Expect = 8.392e-106
Identity = 197/469 (42.00%), Postives = 279/469 (59.49%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSET--ADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSA----SHFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAK--IYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLE-LLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVD+  +  FP+YW      Q+  P++RG WF   +W PL  E+ ++ IE+EHL  +      +T   D   + +  K  ++  SL +   H+DW+  D V++Y+D+     +  +  +LG +K    G++L+RGY  EA  ED+ P  TH+VFV+HGIGQKM  G I      +R   RK+  K F   +  ++ VEFLPVEWR  L LDG+TV+ ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLYS+FC+R+P FE KGGKVS +AHSLG V+ YDI+  W P +  + E+    +  +    S+E + QL   L   + ++  LE  LV  +A             R + P             K+EN FC+GSPLAVFLALRG++P      DHILP  +C R+FN+FHP DPV YRLEPLI + Y+NI PV+I+     N  PYD
Sbjct:  234 RGGLYEVDIKEKECFPVYWKQ----QDHIPVMRGQWFIDGTWLPL-EEEESDLIEEEHLNHFRGQQMQDTIETDLVVKTVDSKDAIH--SLKLSRTHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASPEDRPPHTTHIVFVVHGIGQKMDQGRIIKNTGMLREGVRKMEDKHFS--KHKDEHVEFLPVEWRSKLTLDGDTVESITPDKVRGLRDLLNSSAMDIMYYNSPLYRDEITKGLTQELNRLYSLFCSRNPEFEEKGGKVSIVAHSLGCVITYDIITGWDPVRFCLQEHRAVEEETDLRWMSYEEK-QLLQQLKNTRSRLLDLENQLVALEAS------------RPSVPPALKF--------KVENFFCMGSPLAVFLALRGIRPGISCHQDHILPTSICSRLFNVFHPTDPVAYRLEPLILKHYSNIAPVQIHWSSATNPTPYD 672          

HSP 2 Score: 53.9138 bits (128), Expect = 8.447e-7
Identity = 33/90 (36.67%), Postives = 47/90 (52.22%), Query Frame = 2
Query: 2429 DETASSAESVMAYPAVENTIKNLADDISPGVSNSVETRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFMLTHIFGHLGEIGNP 2698
            +E  S  ES  AY      +  +   +SP    S+E  L+ RID++L E   ES Y S +TSHT YW S ++ +F+LT I+     I  P
Sbjct:  757 EEEQSRTESQSAY-----GLSTMIRPMSPTADTSLE--LERRIDFELREGLVESRYWSTVTSHTGYWCSHDIALFLLTFIYKQKSTISAP 839          
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Match: ddhd1a (phospholipase DDHD1 [Source:NCBI gene;Acc:101163939])

HSP 1 Score: 340.887 bits (873), Expect = 2.867e-102
Identity = 197/501 (39.32%), Postives = 279/501 (55.69%), Query Frame = 2
Query:  470 RGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETAD-----------------------------GFAQQISQKLHLN-----VKSLVVGGYHIDWYDQDSVFIYTDSAS----HFIRHRLGLNKV---GSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAK--IYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLE-LLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYD 1840
            RG LYEVD+  +  FP+YW      Q+  P++RG WF   +W PL  E+ ++ IE+EHL  +      +T +                             G+      + H       + SL +   H+DW+  D V++Y+D+ +      +  +LG +K    G++L+RGY  EA  ED+ P  TH+VFV+HGIGQKM  G I      +R   RK+  K F   +  ++ VEFLPVEWR  L LDG+TV+ ITP++ +GLR+++NS+A+DI+YY+SP+YR E+   L  ELNRLYS+FC+R+P FE KGGKVS +AHSLG V+ YDI+  W P +  + E+    +  +    S+E + QL   L   + ++  LE  LV  +A             R + P             K+EN FC+GSPLAVFLALRG++P      DHILP  +C R+FN+FHP DPV YRLEPLI + Y+NI PV+I+     N  PYD
Sbjct:  234 RGGLYEVDIKEKECFPVYWKQ----QDHIPVMRGQWFIDGTWLPL-EEEESDLIEEEHLNHFRGQQMQDTIETDLVVKTVDSKDVLFHLPPFYLPFLFKWSGYQTSAKTRCHKRKRCQAIHSLKLSRTHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASPEDRPPHTTHIVFVVHGIGQKMDQGRIIKNTGMLREGVRKMEDKHFS--KHKDEHVEFLPVEWRSKLTLDGDTVESITPDKVRGLRDLLNSSAMDIMYYNSPLYRDEITKGLTQELNRLYSLFCSRNPEFEEKGGKVSIVAHSLGCVITYDIITGWDPVRFCLQEHRAVEEETDLRWMSYEEK-QLLQQLKNTRSRLLDLENQLVALEAS------------RPSVPPALKF--------KVENFFCMGSPLAVFLALRGIRPGISCHQDHILPTSICSRLFNVFHPTDPVAYRLEPLILKHYSNIAPVQIHWSSATNPTPYD 706          

HSP 2 Score: 53.9138 bits (128), Expect = 8.410e-7
Identity = 33/90 (36.67%), Postives = 47/90 (52.22%), Query Frame = 2
Query: 2429 DETASSAESVMAYPAVENTIKNLADDISPGVSNSVETRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFMLTHIFGHLGEIGNP 2698
            +E  S  ES  AY      +  +   +SP    S+E  L+ RID++L E   ES Y S +TSHT YW S ++ +F+LT I+     I  P
Sbjct:  791 EEEQSRTESQSAY-----GLSTMIRPMSPTADTSLE--LERRIDFELREGLVESRYWSTVTSHTGYWCSHDIALFLLTFIYKQKSTISAP 873          
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Match: ddhd2 (DDHD domain containing 2 [Source:NCBI gene;Acc:101160488])

HSP 1 Score: 124.405 bits (311), Expect = 6.725e-29
Identity = 148/578 (25.61%), Postives = 240/578 (41.52%), Query Frame = 2
Query:  338 WFY----KENKLWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWF-------RVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQI----SQKLHLNVKSLVVG----GYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKS-EARIEDKLPD-ITHLVFVIHGIGQK--MKGGDITYQVSKIRAVCRKVTKKFFPLLEEAN--QRVEFLPVEWRKSLVLDGNTVD----LITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILIN-----------------------WSPAKIYEYLETLDTDNKDKTS-----HENRMQLFSDLNVAKEKVHHLELLVLTKA--------------------EQENTNRGQTNFRRANFPSNFINGTLWKV--------LPKL----ENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRI 1804
            W++     ++  W+PF   DS +LE       N     ++  +  I V G+ Y+V V  R  + +YW      Q    + R TWF       R   + P D  K+  +  KE +          T+D + ++I     + + ++   L++     G   DW           S S   R R         + RG  S    I D  PD + HLVF++HGIG    ++   I   V+  R+    +    +   ++     RVEFLPV W  +L  D   VD     IT      LR+  N T LD+ +Y+SP Y   ++ ++  E+NRLY++F  R P F      VS + HSLG+++L+D+L N                        +   + +YL+ L ++N D  S       +   L   L   K+ +++++   L +                     E    +  Q+ F RA   ++ ++   + V         P+L    +  F  GSP+ +FL +RGLK      ID       CK  +NI+HP DPV YR+EP+I  +  ++EP+ I
Sbjct:   18 WYFCCRADDSTSWLPFSREDSDKLE-------NTYTTGNQDEEVVIAVDGERYDVHVKERKRYAVYWE-----QAPTEVRRCTWFYKGDKDTRFMPY-PEDFSKMLEEAFKEAV----------TSDQWKKKIDFPTGETVIIHNPKLIMQYQPIGLQDDW---------ISSPSEQTRPR--------TVKRGVDSIPIDIPDGEPDKVDHLVFMVHGIGPACDLRFRSIIQCVNDFRSASLSLLASHYKRAQQDGLVGRVEFLPVNWHSALHGDATGVDEDIQRITLPSISRLRHFTNDTLLDLFFYNSPTYCQTIVDTVASEINRLYALFKQRHPDFNR---AVSLVGHSLGSLILFDLLTNQKTESKVPSGDPSSLSSNTLEQILTKLDLKQYLDILKSENLDLESLSLCKDSDLKDLGIPLGPRKKILNYIKRRWLPEECKAAATLQMQDPQIPGHDADELAGLSSEQSRFYRAQAVTSAVDYEYFDVGIGQVSIDYPQLAFQPQAFFAFGSPIGMFLTVRGLK-----RIDPNYTFPTCKSFYNIYHPYDPVAYRIEPMI-VSEVDLEPMLI 546          
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Match: SMESG000016266.1 (SMESG000016266.1)

HSP 1 Score: 1630.15 bits (4220), Expect = 0.000e+0
Identity = 858/864 (99.31%), Postives = 860/864 (99.54%), Query Frame = 2
Query:  110 MSRIWSDLENKSDNSLLDTLCLPDNDQAYXXXXXXXXXXXXXXXXXXXXXRLESQNSYSESKTSNILLPLYPEKIRWFYKENKLWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYDSSGFDETSVVDIVITRDSLRPDKPVIDEFSQKSTSEGITYSLPKSSHHTLAGKLVKLFYKFKQSAQNKLANSVVNQVVSNHEVDLLEGSSEXXXXXXXXXXXXXXXXXVSRSIHNNNQATKAKFQSQPRLSLSKCSSFRRSNRPVWMEGSPFTXXXXXXXXXEIEVAKDMEMILNTSNVKFRPKTIRYSATRELSGDETASSAESVMAYPAVENTIKNLADDISPGVSNSVETRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFMLTHIFGHLGEIGNPR 2701
            MSRIWSDLENKSDNSLLDTLCLPDNDQAYDSDISVNDNASNVSSVFNNSVRLESQNSYSESKTSNILLPLYPEKIRWFYKENKLWIPFCGYDSLRLETKFRELTNQSVVSSESVKEKIVVRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYDSSGFDETSVVDIVITRDSLRPDKPVIDEFSQKSTSEGITYSLPKSSHHTLAGKLVKLFYKFKQSAQNKLANSVVNQ+VSNHEVDLLEGSSENNLLKIKKKRKRNKTNLVSRSIHNNNQATKAKFQSQPRLSLSKCSSFRRSNRPV MEGSPFTRRSSLRRLSEIEVAKDMEMILNTSNVKFRPKTIRYSATRELSGDET SSAESVMAYPAVENTIKNLADDI  GVSNSVETRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFMLT+IFGHLGEIGNPR
Sbjct:    1 MSRIWSDLENKSDNSLLDTLCLPDNDQAYDSDISVNDNASNVSSVFNNSVRLESQNSYSESKTSNILLPLYPEKIRWFYKENKLWIPFCGYDSLRLETKFRELTNQSVVSSESVKEKIVVRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYDSSGFDETSVVDIVITRDSLRPDKPVIDEFSQKSTSEGITYSLPKSSHHTLAGKLVKLFYKFKQSAQNKLANSVVNQMVSNHEVDLLEGSSENNLLKIKKKRKRNKTNLVSRSIHNNNQATKAKFQSQPRLSLSKCSSFRRSNRPVLMEGSPFTRRSSLRRLSEIEVAKDMEMILNTSNVKFRPKTIRYSATRELSGDETGSSAESVMAYPAVENTIKNLADDIFAGVSNSVETRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFMLTNIFGHLGEIGNPR 864          
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Match: SMESG000016266.1 (SMESG000016266.1)

HSP 1 Score: 1579.3 bits (4088), Expect = 0.000e+0
Identity = 839/864 (97.11%), Postives = 841/864 (97.34%), Query Frame = 2
Query:  110 MSRIWSDLENKSDNSLLDTLCLPDNDQAYXXXXXXXXXXXXXXXXXXXXXRLESQNSYSESKTSNILLPLYPEKIRWFYKENKLWIPFCGYDSLRLETKFRELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYDSSGFDETSVVDIVITRDSLRPDKPVIDEFSQKSTSEGITYSLPKSSHHTLAGKLVKLFYKFKQSAQNKLANSVVNQVVSNHEVDLLEGSSEXXXXXXXXXXXXXXXXXVSRSIHNNNQATKAKFQSQPRLSLSKCSSFRRSNRPVWMEGSPFTXXXXXXXXXEIEVAKDMEMILNTSNVKFRPKTIRYSATRELSGDETASSAESVMAYPAVENTIKNLADDISPGVSNSVETRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFMLTHIFGHLGEIGNPR 2701
            MSRIWSDLENKSDNSLLDTLCLPDNDQAYDSDISVNDNASNVSSVFNNSVRLESQNSYSESKTSNILLPLYPEKIRWFYKENKLWIPFCGYDSLRLETKFRELTNQSVVSSESVKEKIVVRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFR                   LENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYDSSGFDETSVVDIVITRDSLRPDKPVIDEFSQKSTSEGITYSLPKSSHHTLAGKLVKLFYKFKQSAQNKLANSVVNQ+VSNHEVDLLEGSSENNLLKIKKKRKRNKTNLVSRSIHNNNQATKAKFQSQPRLSLSKCSSFRRSNRPV MEGSPFTRRSSLRRLSEIEVAKDMEMILNTSNVKFRPKTIRYSATRELSGDET SSAESVMAYPAVENTIKNLADDI  GVSNSVETRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFMLT+IFGHLGEIGNPR
Sbjct:    1 MSRIWSDLENKSDNSLLDTLCLPDNDQAYDSDISVNDNASNVSSVFNNSVRLESQNSYSESKTSNILLPLYPEKIRWFYKENKLWIPFCGYDSLRLETKFRELTNQSVVSSESVKEKIVVRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFR-------------------LENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKIPYDSSGFDETSVVDIVITRDSLRPDKPVIDEFSQKSTSEGITYSLPKSSHHTLAGKLVKLFYKFKQSAQNKLANSVVNQMVSNHEVDLLEGSSENNLLKIKKKRKRNKTNLVSRSIHNNNQATKAKFQSQPRLSLSKCSSFRRSNRPVLMEGSPFTRRSSLRRLSEIEVAKDMEMILNTSNVKFRPKTIRYSATRELSGDETGSSAESVMAYPAVENTIKNLADDIFAGVSNSVETRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFMLTNIFGHLGEIGNPR 845          
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Match: SMESG000014209.1 (SMESG000014209.1)

HSP 1 Score: 377.096 bits (967), Expect = 9.557e-118
Identity = 214/516 (41.47%), Postives = 314/516 (60.85%), Query Frame = 2
Query:  317 LYPEKIRWFYK-----ENKLWIPFCGYDSLRLETKFRELT-NQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLN---KVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQ--LFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKI 1831
            L+PE+ RWFYK     E  ++  F GYDSLRLETKFREL+  +   + ES  EKI+V+ DL+E DV+ RI  PIYW    D  ++F I RGTWF   +++PL  E +A+ IE + +     N  S         +SQK    + ++    Y I+WY+    ++Y  ++  +   +L ++   K G K+ RGYK +  ++DK  DI+HL FV+HGIGQ++  G I  Q  K++   + V KK++     +  R+EFLP+EWR +L LDG  +D ITP   KGLR + N+T +DILYYSS +Y+ E+   ++ E NR+YSMFC+R+PYFE KGGKVS IAHSLG+V+ YDI+ +W    I     +L  D + K+S E  ++    +DL   +  + + E  ++   +  +T       ++ NFPSNF  G LWK +  ++N F +GSPL VFL LRGL P+N+   + ILP+ +C+R+FNI+H +DPV YRLEPL+ + Y  I+PV I  L   ++I
Sbjct:   52 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWT---DSNDNFDIYRGTWFIADTFEPL-IENLADAIESQFMM----NFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNI-NLNNSLSFDYQFKSSDELLLKNRKLTDL---QNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEI 554          
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Match: SMESG000014209.1 (SMESG000014209.1)

HSP 1 Score: 376.711 bits (966), Expect = 2.209e-117
Identity = 214/516 (41.47%), Postives = 314/516 (60.85%), Query Frame = 2
Query:  317 LYPEKIRWFYK-----ENKLWIPFCGYDSLRLETKFRELT-NQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYWNAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLN---KVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQ--LFSDLNVAKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRIYPLDHPNKI 1831
            L+PE+ RWFYK     E  ++  F GYDSLRLETKFREL+  +   + ES  EKI+V+ DL+E DV+ RI  PIYW    D  ++F I RGTWF   +++PL  E +A+ IE + +     N  S         +SQK    + ++    Y I+WY+    ++Y  ++  +   +L ++   K G K+ RGYK +  ++DK  DI+HL FV+HGIGQ++  G I  Q  K++   + V KK++     +  R+EFLP+EWR +L LDG  +D ITP   KGLR + N+T +DILYYSS +Y+ E+   ++ E NR+YSMFC+R+PYFE KGGKVS IAHSLG+V+ YDI+ +W    I     +L  D + K+S E  ++    +DL   +  + + E  ++   +  +T       ++ NFPSNF  G LWK +  ++N F +GSPL VFL LRGL P+N+   + ILP+ +C+R+FNI+H +DPV YRLEPL+ + Y  I+PV I  L   ++I
Sbjct:   71 LHPEETRWFYKSVEKSEKNIFKCFSGYDSLRLETKFRELSIFKGKSNLESSTEKIIVKSDLFEADVVKRICVPIYWT---DSNDNFDIYRGTWFIADTFEPL-IENLADAIESQFMM----NFLSLQYSCLDSNVSQKNRKVIHAMKYSNYLIEWYNLQEAYLYDMNSMAYRMKKLKMSNHSKFGQKIVRGYKEKTSLDDKQSDISHLCFVVHGIGQRL-AGHINRQCYKLKQSYKSVLKKYYAPHVTSKFRIEFLPIEWRTNLNLDGGMIDSITPKDFKGLRTIFNNTVMDILYYSSSLYQIEISHGVQSEFNRMYSMFCSRNPYFECKGGKVSIIAHSLGSVICYDIIRSWGNPNI-NLNNSLSFDYQFKSSDELLLKNRKLTDL---QNNISNCEEDIIDTFKHSHTKSTLKREKQPNFPSNFKTGNLWKEVKNVDNFFMLGSPLPVFLVLRGLNPKNVVDQNDILPKHVCQRIFNIYHSSDPVAYRLEPLLIKEYLQIDPVHIKLLTSEDEI 573          
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Match: SMESG000068161.1 (SMESG000068161.1)

HSP 1 Score: 353.214 bits (905), Expect = 1.443e-108
Identity = 196/502 (39.04%), Postives = 296/502 (58.96%), Query Frame = 2
Query:  332 IRWFYKENKLWIPFCGYDSLRLETKFR---ELTNQXXXXXXXXXXXXXXRGDLYEVDVLNRIGFPIYW-NAIDDGQESFPIIRGTWFRVASWQPLDSEKIANKIEKEHLKLYG--DNNSSETADGF----AQQISQKLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNRGYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTKKFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTALDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHSLGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNV-AKEKVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLFCVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLEPLINQTYANIEPVRI 1804
            +RWFY+E  +W  F GYDSL+LE   R   E+   +        + I+VRG++Y V++L R  F I++  + DD +E   IIRGTWF   S  PL++E ++N IE +HLKL+G  D+   +    F    A ++S++L L V S+ V  YHI+W   + VFI   S   ++  ++GL +VG+K+ RGY   A + DKLP+I HL FVI GIG+      I  +VS +  V  K+          + Q++ F+PV+W+KSL  + +  + I+P+ N GLR +VNS++ DILYY++P++  ++I SL+ ELNR+YS+FC  + YF    GKVSAIAHSLG+V+L+DIL NWSP + Y   +  + ++  K    +   +F+  +   K  V   +L +  + + EN     T F+                  ++ENLF +GSPLA+FLA RG+K       + ++   +CKR +NIFHP DP+VYR+EPLIN+ Y+ I+PV I
Sbjct:   22 VRWFYREKSVWTAFTGYDSLQLEENHRSINEMDVTNTNFQRLKDDYILVRGNMYMVNLLRRKMFSIFYIESDDDNEEPLTIIRGTWFHNDSHLPLETELLSNAIEDQHLKLFGACDDKKKKKETNFVGKVAHKLSKQLKLKVFSMDVNDYHIEWGGMNDVFINKPSTKQYVLDKMGLGRVGNKICRGYHETALMNDKLPNIDHLCFVIEGIGKTYGNNTIYEKVSDLMKVTDKIISD---TSSYSKQKIAFIPVDWQKSLAFNYDIFENISPDNNPGLRMIVNSSSQDILYYTNPLFYSDIIESLKSELNRVYSIFCRHNDYFVKNNGKVSAIAHSLGSVILFDILSNWSPQQQYNNWKEFEINSGAKAESSS---IFNGKSYETKNNVQKFQLHLFQQNDSENRLPIHTIFQF-----------------QIENLFFIGSPLAIFLAFRGIKLHPNGLQEDLIKPHICKRFYNIFHPNDPLVYRIEPLINEYYSKIKPVLI 500          

HSP 2 Score: 62.3882 bits (150), Expect = 1.339e-9
Identity = 40/134 (29.85%), Postives = 61/134 (45.52%), Query Frame = 2
Query: 2279 MEGSPFTXXXXXXXXXEIEVAKDMEMILNTSNVKFRPKTIRYSATRELS----GDETASSAESVMAYPAVENTIKNLADDISPGVSNSVETRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFMLTHI 2668
            M G P T     + ++ IE   D  ++     V     T R S   E S    GD       + M +       K +  +I P     +   LK R+D+KLP++ YE+SY S ++SH SYW+  +L  F+L+ I
Sbjct:  584 MRGKPATNFYYQKNMNIIERRNDSNVVYTIKAVSLHDSTSRGSNYNENSLTNTGDRNKLQGLNNMNFSKNSVPSKTIKSEIEPQSDLEIHKTLKWRLDFKLPQNHYENSYFSAISSHESYWTDEDLSFFILSQI 717          
The following BLAST results are available for this feature:
BLAST of DDHD domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DDHD12.796e-11842.18DDHD domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
DDHD14.960e-11842.31DDHD domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
DDHD19.797e-11842.31DDHD domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
DDHD11.614e-11739.96DDHD domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
DDHD12.989e-11741.68DDHD domain containing 1 [Source:HGNC Symbol;Acc:H... [more]
back to top
BLAST of DDHD domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ipla-19.096e-6432.40Intracelllar PhosphoLipase A family [Source:UniPr... [more]
ipla-11.386e-6331.78Intracelllar PhosphoLipase A family [Source:UniPr... [more]
ipla-11.696e-6332.40Intracelllar PhosphoLipase A family [Source:UniPr... [more]
ipla-11.920e-6332.40Intracelllar PhosphoLipase A family [Source:UniPr... [more]
ipla-11.920e-6332.40Intracelllar PhosphoLipase A family [Source:UniPr... [more]
back to top
BLAST of DDHD domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PAPLA16.135e-3225.97gene:FBgn0031990 transcript:FBtr0344863[more]
PAPLA16.135e-3225.97gene:FBgn0031990 transcript:FBtr0302595[more]
PAPLA15.392e-3026.25gene:FBgn0031990 transcript:FBtr0339673[more]
PAPLA11.299e-2926.05gene:FBgn0031990 transcript:FBtr0079641[more]
rdgB1.638e-839.47gene:FBgn0003218 transcript:FBtr0301535[more]
back to top
BLAST of DDHD domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ddhd1a3.942e-13139.96DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GEN... [more]
ddhd1a1.448e-13039.96DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GEN... [more]
ddhd1a2.824e-12638.05DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GEN... [more]
ddhd1a2.824e-12638.05DDHD domain containing 1a [Source:ZFIN;Acc:ZDB-GEN... [more]
ddhd1b2.596e-11342.03DDHD domain containing 1b [Source:ZFIN;Acc:ZDB-GEN... [more]
back to top
BLAST of DDHD domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
DDHD11.980e-13441.64DDHD domain containing 1 [Source:NCBI gene;Acc:100... [more]
DDHD19.024e-11743.55DDHD domain containing 1 [Source:NCBI gene;Acc:100... [more]
DDHD11.693e-9541.75DDHD domain containing 1 [Source:NCBI gene;Acc:100... [more]
DDHD11.675e-9440.70DDHD domain containing 1 [Source:NCBI gene;Acc:100... [more]
DDHD11.290e-9039.06DDHD domain containing 1 [Source:NCBI gene;Acc:100... [more]
back to top
BLAST of DDHD domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ddhd12.213e-11842.31DDHD domain containing 1 [Source:MGI Symbol;Acc:MG... [more]
Ddhd15.607e-11842.31DDHD domain containing 1 [Source:MGI Symbol;Acc:MG... [more]
Ddhd14.054e-11440.08DDHD domain containing 1 [Source:MGI Symbol;Acc:MG... [more]
Ddhd19.305e-3845.33DDHD domain containing 1 [Source:MGI Symbol;Acc:MG... [more]
Ddhd21.668e-3326.55DDHD domain containing 2 [Source:MGI Symbol;Acc:MG... [more]
back to top
BLAST of DDHD domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O46606|DDHD1_BOVIN4.623e-11742.31Phospholipase DDHD1 OS=Bos taurus OX=9913 GN=DDHD1... [more]
sp|Q8NEL9|DDHD1_HUMAN1.068e-11642.31Phospholipase DDHD1 OS=Homo sapiens OX=9606 GN=DDH... [more]
sp|Q80YA3|DDHD1_MOUSE1.444e-9644.11Phospholipase DDHD1 OS=Mus musculus OX=10090 GN=Dd... [more]
sp|Q80Y98|DDHD2_MOUSE1.167e-3226.55Phospholipase DDHD2 OS=Mus musculus OX=10090 GN=Dd... [more]
sp|O94830|DDHD2_HUMAN2.512e-3227.70Phospholipase DDHD2 OS=Homo sapiens OX=9606 GN=DDH... [more]
back to top
BLAST of DDHD domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3JQ639.828e-14646.11phospholipase DDHD1 OS=Lingula unguis OX=7574 GN=L... [more]
A0A267G2H65.919e-14346.40DDHD domain-containing protein OS=Macrostomum lign... [more]
A0A267DGF85.278e-14147.81DDHD domain-containing protein (Fragment) OS=Macro... [more]
V3YZE13.966e-13646.27DDHD domain-containing protein OS=Lottia gigantea ... [more]
A0A0L8GHQ71.542e-13241.50DDHD domain-containing protein (Fragment) OS=Octop... [more]
back to top
BLAST of DDHD domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ddhd1b7.555e-11837.54DDHD domain containing 1b [Source:ZFIN;Acc:ZDB-GEN... [more]
ddhd1a1.136e-11341.91phospholipase DDHD1 [Source:NCBI gene;Acc:10302386... [more]
ddhd1a1.130e-11040.08phospholipase DDHD1 [Source:NCBI gene;Acc:10302386... [more]
ddhd1a2.132e-10437.04phospholipase DDHD1 [Source:NCBI gene;Acc:10302386... [more]
sec23ip1.246e-2728.11SEC23 interacting protein [Source:NCBI gene;Acc:10... [more]
back to top
BLAST of DDHD domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000010367.15.102e-2854.95pep scaffold:Pmarinus_7.0:GL490372:1378:4627:-1 ge... [more]
back to top
BLAST of DDHD domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
DDL14.432e-1429.06DDHD domain-containing phospholipase A1; mitochond... [more]
back to top
BLAST of DDHD domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO409742.392e-8743.01Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371341.872e-2428.02Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of DDHD domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ddhd1b9.027e-11740.71phospholipase DDHD1 [Source:NCBI gene;Acc:10117179... [more]
ddhd1b1.828e-11640.71phospholipase DDHD1 [Source:NCBI gene;Acc:10117179... [more]
ddhd1a8.392e-10642.00phospholipase DDHD1 [Source:NCBI gene;Acc:10116393... [more]
ddhd1a2.867e-10239.32phospholipase DDHD1 [Source:NCBI gene;Acc:10116393... [more]
ddhd26.725e-2925.61DDHD domain containing 2 [Source:NCBI gene;Acc:101... [more]
back to top
BLAST of DDHD domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000016266.10.000e+099.31SMESG000016266.1[more]
SMESG000016266.10.000e+097.11SMESG000016266.1[more]
SMESG000014209.19.557e-11841.47SMESG000014209.1[more]
SMESG000014209.12.209e-11741.47SMESG000014209.1[more]
SMESG000068161.11.443e-10839.04SMESG000068161.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026215 ID=SMED30026215|Name=DDHD domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2895bp
CTGAAATATTGATGAGTAGTTAATTTTAATGATTATAATTTTCGTAAAAA
TAACAAAGATTATATCCAAGAATTTTTATTTACGCTATTGATATTTCAAG
CAAAAATTAATGAGCAGAATATGGTCGGATTTAGAAAATAAATCTGATAA
TTCACTATTAGATACTTTATGTTTACCGGATAATGACCAAGCATATGATA
GTGATATTTCAGTGAATGATAATGCTTCCAATGTTTCATCGGTGTTTAAT
AATTCAGTTCGACTTGAATCCCAGAACAGTTACTCTGAATCCAAAACTTC
AAACATTCTACTTCCATTATATCCGGAAAAAATCAGATGGTTTTATAAGG
AAAATAAATTATGGATTCCATTTTGTGGTTATGATTCGTTGAGACTGGAG
ACCAAATTTCGCGAATTGACCAATCAGAGTGTAGTGAGTTCTGAAAGTGT
TAAGGAAAAAATCGTCGTTCGAGGAGATCTATATGAAGTAGATGTTTTGA
ATCGAATCGGATTTCCAATCTACTGGAATGCAATCGATGATGGACAGGAA
TCGTTTCCCATAATAAGGGGCACTTGGTTTCGGGTGGCATCTTGGCAGCC
GCTAGACAGTGAGAAAATAGCGAATAAGATCGAAAAAGAACATTTGAAAC
TGTATGGGGACAATAATTCTAGTGAAACTGCCGACGGATTTGCTCAACAG
ATTTCACAGAAATTGCATTTAAATGTGAAATCCTTGGTGGTCGGTGGTTA
CCATATCGATTGGTACGACCAGGACAGCGTTTTCATTTACACGGACTCGG
CCTCTCATTTCATTCGACATCGGCTAGGATTGAATAAAGTCGGGAGTAAG
CTAAACCGGGGATACAAATCCGAGGCCCGCATCGAAGACAAATTGCCCGA
CATAACCCACTTAGTGTTTGTAATTCACGGCATTGGCCAAAAAATGAAAG
GCGGAGATATCACTTATCAAGTTTCAAAAATTAGAGCTGTGTGTCGAAAA
GTGACAAAAAAGTTTTTCCCTCTATTAGAAGAAGCAAATCAGAGAGTTGA
ATTTCTTCCGGTAGAATGGAGGAAATCTCTAGTTCTCGATGGGAATACTG
TAGATTTGATAACCCCTAATAGGAATAAAGGATTAAGAAATGTTGTAAAC
AGTACAGCATTGGACATTCTCTATTATTCAAGTCCAATATATCGTCCGGA
AATGATTGGCTCGTTAAGGTGCGAATTGAATAGGTTATACAGTATGTTCT
GTGCAAGAAGTCCTTATTTCGAAACCAAAGGTGGAAAAGTTTCTGCAATT
GCCCATTCATTAGGAGCTGTTTTGCTTTATGATATTCTAATCAATTGGTC
CCCAGCAAAGATATACGAGTACCTGGAGACCTTAGACACAGATAATAAAG
ACAAAACAAGCCATGAAAATCGAATGCAACTATTTTCCGATCTCAATGTT
GCCAAAGAAAAAGTGCATCACCTTGAACTTCTTGTTTTAACGAAAGCTGA
ACAGGAAAACACCAATAGAGGACAGACAAATTTTCGGAGAGCTAATTTCC
CAAGTAATTTTATTAACGGAACTCTGTGGAAAGTTTTACCAAAACTGGAA
AATTTGTTTTGCGTTGGCTCGCCGTTGGCAGTATTTCTCGCATTGCGTGG
ACTGAAACCGGAAAACCTTTCGACAATTGACCACATATTACCGGAACAAT
TATGCAAAAGAGTGTTCAATATTTTCCATCCCGCAGACCCTGTCGTTTAT
CGACTTGAGCCTCTCATAAATCAAACCTATGCCAATATTGAACCGGTACG
CATTTACCCATTAGACCACCCCAATAAAATACCCTACGACAGTTCCGGTT
TTGATGAGACATCCGTCGTTGACATAGTAATAACCAGAGATTCTTTGCGA
CCGGATAAGCCGGTAATTGATGAGTTCTCACAAAAATCAACATCTGAAGG
AATCACTTATTCGTTACCAAAGTCGTCTCATCACACTTTAGCAGGAAAAC
TAGTCAAGCTATTCTATAAATTCAAACAATCCGCTCAAAATAAATTAGCC
AATTCCGTAGTTAACCAGGTGGTATCAAATCATGAGGTTGATCTCCTTGA
AGGATCATCAGAAAATAACCTTCTCAAAATCAAGAAAAAAAGAAAACGAA
ACAAAACTAATTTGGTTTCGAGAAGTATTCATAATAATAATCAAGCTACT
AAAGCTAAATTTCAAAGCCAACCGAGATTGAGTCTTTCGAAATGTTCATC
GTTTCGAAGAAGTAATAGACCTGTCTGGATGGAGGGATCTCCATTCACTC
GAAGGAGTAGTTTGCGTCGGTTATCGGAAATAGAGGTCGCCAAAGATATG
GAGATGATTCTCAATACAAGTAACGTAAAGTTTCGGCCGAAAACCATTCG
GTATTCAGCAACGAGAGAGTTGAGTGGTGATGAAACTGCCAGCAGTGCTG
AGTCTGTAATGGCGTATCCAGCAGTTGAAAACACAATCAAAAACCTTGCT
GATGATATTTCCCCTGGTGTGTCCAATTCTGTGGAAACTCGGTTGAAAGT
GCGAATCGATTACAAATTGCCCGAGAGCCGTTATGAGAGCTCCTATTTGT
CTGTGTTGACGTCTCACACGAGCTATTGGAGCAGTCCCGAGCTCTGCATG
TTTATGTTGACGCATATTTTCGGGCATCTCGGAGAAATTGGAAATCCACG
ATAATCTCTTATATTTTATATAGATCTATTTTATTTTCTGATCCGATCTT
ATTTTCAATTGCAATATTTTTTAACTTGGTTTATATATCAAAACAAGAAA
CTAACTAAAATTGTAGTAAAAAATTCTTTGAATGAGAAGGGATATTTTAT
TTGTATTTTTAGTGCCGATATGAATCAGGCCCCCAGATCGGAAGA
back to top

protein sequence of SMED30026215-orf-1

>SMED30026215-orf-1 ID=SMED30026215-orf-1|Name=SMED30026215-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=865bp
MSRIWSDLENKSDNSLLDTLCLPDNDQAYDSDISVNDNASNVSSVFNNSV
RLESQNSYSESKTSNILLPLYPEKIRWFYKENKLWIPFCGYDSLRLETKF
RELTNQSVVSSESVKEKIVVRGDLYEVDVLNRIGFPIYWNAIDDGQESFP
IIRGTWFRVASWQPLDSEKIANKIEKEHLKLYGDNNSSETADGFAQQISQ
KLHLNVKSLVVGGYHIDWYDQDSVFIYTDSASHFIRHRLGLNKVGSKLNR
GYKSEARIEDKLPDITHLVFVIHGIGQKMKGGDITYQVSKIRAVCRKVTK
KFFPLLEEANQRVEFLPVEWRKSLVLDGNTVDLITPNRNKGLRNVVNSTA
LDILYYSSPIYRPEMIGSLRCELNRLYSMFCARSPYFETKGGKVSAIAHS
LGAVLLYDILINWSPAKIYEYLETLDTDNKDKTSHENRMQLFSDLNVAKE
KVHHLELLVLTKAEQENTNRGQTNFRRANFPSNFINGTLWKVLPKLENLF
CVGSPLAVFLALRGLKPENLSTIDHILPEQLCKRVFNIFHPADPVVYRLE
PLINQTYANIEPVRIYPLDHPNKIPYDSSGFDETSVVDIVITRDSLRPDK
PVIDEFSQKSTSEGITYSLPKSSHHTLAGKLVKLFYKFKQSAQNKLANSV
VNQVVSNHEVDLLEGSSENNLLKIKKKRKRNKTNLVSRSIHNNNQATKAK
FQSQPRLSLSKCSSFRRSNRPVWMEGSPFTRRSSLRRLSEIEVAKDMEMI
LNTSNVKFRPKTIRYSATRELSGDETASSAESVMAYPAVENTIKNLADDI
SPGVSNSVETRLKVRIDYKLPESRYESSYLSVLTSHTSYWSSPELCMFML
THIFGHLGEIGNPR*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000420parapharyngeal region
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR004177DDHD_dom
Vocabulary: molecular function
TermDefinition
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR004177DDHD domainSMARTSM01127DDHD_2acoord: 495..855
e-value: 4.6E-29
score: 112.6
IPR004177DDHD domainPFAMPF02862DDHDcoord: 496..853
e-value: 1.0E-40
score: 140.3
IPR004177DDHD domainPROSITEPS51043DDHDcoord: 492..855
score: 29.638
NoneNo IPR availablePANTHERPTHR23509:SF32PHOSPHOLIPASE DDHD1coord: 780..856
NoneNo IPR availablePANTHERPTHR23509:SF32PHOSPHOLIPASE DDHD1coord: 33..579
NoneNo IPR availablePANTHERPTHR23509FAMILY NOT NAMEDcoord: 33..579
NoneNo IPR availablePANTHERPTHR23509FAMILY NOT NAMEDcoord: 780..856