ER membrane protein complex subunit 10

Overview
NameER membrane protein complex subunit 10
Smed IDSMED30026188
Length (bp)847
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of ER membrane protein complex subunit 10 (SMED30026188) t-SNE clustered cells

Violin plots show distribution of expression levels for ER membrane protein complex subunit 10 (SMED30026188) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ER membrane protein complex subunit 10 (SMED30026188) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ER membrane protein complex subunit 10 (SMED30026188) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30026188

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30026188h1SMcG0018628 dd_Smed_v4_2594_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30026188h1SMcG0018628 dd_Smed_v4_2594_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30026188h1SMcG0018628 dd_Smed_v4_2594_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30026188h1SMcG0018628 dd_Smed_v4_2594_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30026188h1SMcG0018628 dd_Smed_v4_2594_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30026188h1SMcG0018628 dd_Smed_v4_2594_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Human
Match: EMC10 (ER membrane protein complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:27609])

HSP 1 Score: 95.5153 bits (236), Expect = 1.240e-22
Identity = 54/194 (27.84%), Postives = 99/194 (51.03%), Query Frame = 3 
Query:  189 IEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSE--------FIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMP 734
            +EHSF  ++   +  + +L + +    ++ LS +  L+  E+  ++     NG Y++RI              ++ + +  C L+ S+    L + VD  GNVVG+ + T    C     ED D+E      T+  LQ P     P  + +++RLE+++ +K K+ Q + KSF +KYW Y++P+V+ L+M+  P
Sbjct:   56 LEHSFEIDDSANFRKRGSL-LWNQQDGTLSLS-QRQLSEEERGRLRDVAALNGLYRVRIPRRPGALDGLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLEL---FNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWMYIIPVVLFLMMSGAP 243
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Human
Match: EMC10 (ER membrane protein complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:27609])

HSP 1 Score: 93.9745 bits (232), Expect = 2.244e-21
Identity = 54/194 (27.84%), Postives = 99/194 (51.03%), Query Frame = 3 
Query:  189 IEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSE--------FIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMP 734
            +EHSF  ++   +  + +L + +    ++ LS +  L+  E+  ++     NG Y++RI              ++ + +  C L+ S+    L + VD  GNVVG+ + T    C     ED D+E      T+  LQ P     P  + +++RLE+++ +K K+ Q + KSF +KYW Y++P+V+ L+M+  P
Sbjct:   56 LEHSFEIDDSANFRKRGSL-LWNQQDGTLSLS-QRQLSEEERGRLRDVAALNGLYRVRIPRRPGALDGLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLE---LFNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWMYIIPVVLFLMMSGAP 243
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Human
Match: EMC10 (ER membrane protein complex subunit 10 [Source:HGNC Symbol;Acc:HGNC:27609])

HSP 1 Score: 78.9518 bits (193), Expect = 1.322e-16
Identity = 50/188 (26.60%), Postives = 92/188 (48.94%), Query Frame = 3 
Query:  189 IEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSE--------FIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIML 716
            +EHSF  ++   +  + +L + +    ++ LS +  L+  E+  ++     NG Y++RI              ++ + +  C L+ S+    L + VD  GNVVG+ + T    C     ED D+E      T+  LQ P     P  + +++RLE+++ +K K+ Q + KSF +KYW  +L   ++L
Sbjct:   56 LEHSFEIDDSANFRKRGSL-LWNQQDGTLSLS-QRQLSEEERGRLRDVAALNGLYRVRIPRRPGALDGLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLEL---FNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWHIILGGAVLL 237
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Celegans
Match: Y43F8C.7 (pep chromosome:WBcel235:V:19641296:19644030:-1 gene:WBGene00012829.1 transcript:Y43F8C.7.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y43F8C.7)

HSP 1 Score: 52.373 bits (124), Expect = 7.067e-8
Identity = 18/61 (29.51%), Postives = 39/61 (63.93%), Query Frame = 3 
Query:  546 KTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTS 728
            K   H+    +  +P+ + +++++E ++R K      DN+SFL+KYW Y++P+V+  +++S
Sbjct:  163 KGVCHVVGESVLPTPDTAAFVQKMEREKRAKQHGADADNRSFLAKYWMYIVPVVLFAVISS 223
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Celegans
Match: Y43F8C.7 (pep chromosome:WBcel235:V:19641292:19644083:-1 gene:WBGene00012829.1 transcript:Y43F8C.7.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y43F8C.7)

HSP 1 Score: 52.373 bits (124), Expect = 7.067e-8
Identity = 18/61 (29.51%), Postives = 39/61 (63.93%), Query Frame = 3 
Query:  546 KTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTS 728
            K   H+    +  +P+ + +++++E ++R K      DN+SFL+KYW Y++P+V+  +++S
Sbjct:  163 KGVCHVVGESVLPTPDTAAFVQKMEREKRAKQHGADADNRSFLAKYWMYIVPVVLFAVISS 223
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Fly
Match: CG32441 (gene:FBgn0052441 transcript:FBtr0300058)

HSP 1 Score: 58.9214 bits (141), Expect = 4.379e-10
Identity = 48/202 (23.76%), Postives = 103/202 (50.99%), Query Frame = 3 
Query:  180 SMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSN--ENSLTNNEKENIQKSLKSNGFYKIRIA-----GTNSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKS-----QNCHEDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMP-QDAA 746
            ++ ++HS   N E  ++ +  + I S+NS    L+N  +  L+  + + ++K    N FY+++       G  ++FI TS K C+L+ +     L VS++  G V G+ +S  +     +   ED +     +  T   ++   +   P+ + +++++E +   + + E  DN+ F +KYW Y++P+V+++ ++    QD A
Sbjct:   17 TVELQHSLAANSE-SFSFRGNVTIPSLNSG---LANVEQPDLSTADLDLLKKLALGNEFYRLKATVVYSNGAKAQFI-TSNKACRLLQAQLNDVLWVSLEPSGYVTGITVSQDTAPATIECTQEDVNKLLETQFSTDVLIRHAELAPVPDTAGFIQKVEREREARERGEVRDNRGFFAKYWMYIVPVVLLVFISGATNQDGA 213
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Fly
Match: CG32441 (gene:FBgn0052441 transcript:FBtr0300057)

HSP 1 Score: 58.5362 bits (140), Expect = 5.844e-10
Identity = 48/202 (23.76%), Postives = 103/202 (50.99%), Query Frame = 3 
Query:  180 SMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSN--ENSLTNNEKENIQKSLKSNGFYKIRIA-----GTNSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKS-----QNCHEDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMP-QDAA 746
            ++ ++HS   N E  ++ +  + I S+NS    L+N  +  L+  + + ++K    N FY+++       G  ++FI TS K C+L+ +     L VS++  G V G+ +S  +     +   ED +     +  T   ++   +   P+ + +++++E +   + + E  DN+ F +KYW Y++P+V+++ ++    QD A
Sbjct:   30 TVELQHSLAANSE-SFSFRGNVTIPSLNSG---LANVEQPDLSTADLDLLKKLALGNEFYRLKATVVYSNGAKAQFI-TSNKACRLLQAQLNDVLWVSLEPSGYVTGITVSQDTAPATIECTQEDVNKLLETQFSTDVLIRHAELAPVPDTAGFIQKVEREREARERGEVRDNRGFFAKYWMYIVPVVLLVFISGATNQDGA 226
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Zebrafish
Match: emc10 (ER membrane protein complex subunit 10 [Source:NCBI gene;Acc:565829])

HSP 1 Score: 91.6633 bits (226), Expect = 1.729e-21
Identity = 52/199 (26.13%), Postives = 105/199 (52.76%), Query Frame = 3 
Query:  180 SMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSE-----------FIETSLKTCQLISSNF--IVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSVEIK---TTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTS 728
            S+ +EHSF  ++   +  +  L  R    NS+ LS +N L+  ++  ++     +G Y+IR+   + +           ++   ++ C L+ S+   ++ L   V G+  V+G+ + T   +C    +VE  V+++   TT  + +PV    P  + Y++R+E++  +K K+ Q + KSF +KYW Y++P+V+ L+M+ 
Sbjct:   45 SVPLEHSFEVDDVPRFRLRGALQFRGGRENSVYLS-QNQLSEKDRNTLKDVAAVDGLYRIRVPRVSLQVDRQTERQYEGYLTAFVRACALVESHLSDVITLHTDVSGY--VIGISIVTIPGSCR-GIEVEDEVDLEVFNTTISVMAPVTAPVPETAPYIERMEMEMEKKGKNPQ-EQKSFFAKYWMYIVPLVLFLMMSG 238
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Zebrafish
Match: emc10 (ER membrane protein complex subunit 10 [Source:NCBI gene;Acc:565829])

HSP 1 Score: 84.7297 bits (208), Expect = 6.655e-19
Identity = 52/202 (25.74%), Postives = 103/202 (50.99%), Query Frame = 3 
Query:  180 SMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSE-----------FIETSLKTCQLISSNF--IVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSVEIK---TTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQ 737
            S+ +EHSF  ++   +  +  L  R    NS+ LS +N L+  ++  ++     +G Y+IR+   + +           ++   ++ C L+ S+   ++ L   V G+  V+G+ + T   +C    +VE  V+++   TT  + +PV    P  + Y++R+E++  +K K+ Q + KSF +KYW+ +L   + L+ TS  Q
Sbjct:   45 SVPLEHSFEVDDVPRFRLRGALQFRGGRENSVYLS-QNQLSEKDRNTLKDVAAVDGLYRIRVPRVSLQVDRQTERQYEGYLTAFVRACALVESHLSDVITLHTDVSGY--VIGISIVTIPGSCR-GIEVEDEVDLEVFNTTISVMAPVTAPVPETAPYIERMEMEMEKKGKNPQ-EQKSFFAKYWYLILGGAVFLMATSSAQ 241
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Xenopus
Match: emc10 (ER membrane protein complex subunit 10 [Source:NCBI gene;Acc:394497])

HSP 1 Score: 97.8265 bits (242), Expect = 1.622e-23
Identity = 53/194 (27.32%), Postives = 106/194 (54.64%), Query Frame = 3 
Query:  177 SSMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGT------NSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTS 728
            +++ +EHSF  ++ + +  + +L        SI +  +  LT +E+  ++     NG Y+IR+          +E++ + ++ C ++ S+    + V  D  GNVVG+ + T   +C+    ED D+E      TT ++Q P+    P  + +++RLE+++ +K K+ Q + KSF +KYW Y++P+V+ L+M+ 
Sbjct:   54 TNLELEHSFELDDSIHFKKRGSLIWSGTAEQSISIL-QKQLTEDERNKLRDIANLNGLYRIRVPRKLGITEEANEYVTSFVRACSMVESHLSDQISVHTDISGNVVGISIVTFPGSCNGAEVEDVDLEM---FNTTVYIQQPIAAAVPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWMYIIPVVLFLMMSG 242
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Xenopus
Match: emc10 (ER membrane protein complex subunit 10 [Source:NCBI gene;Acc:394497])

HSP 1 Score: 87.0409 bits (214), Expect = 1.234e-19
Identity = 51/193 (26.42%), Postives = 103/193 (53.37%), Query Frame = 3 
Query:  177 SSMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGT------NSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMT 725
            +++ +EHSF  ++ + +  + +L        SI +  +  LT +E+  ++     NG Y+IR+          +E++ + ++ C ++ S+    + V  D  GNVVG+ + T   +C+    ED D+E      TT ++Q P+    P  + +++RLE+++ +K K+ Q + KSF +KYW  +L   ++L++T
Sbjct:   54 TNLELEHSFELDDSIHFKKRGSLIWSGTAEQSISIL-QKQLTEDERNKLRDIANLNGLYRIRVPRKLGITEEANEYVTSFVRACSMVESHLSDQISVHTDISGNVVGISIVTFPGSCNGAEVEDVDLEM---FNTTVYIQQPIAAAVPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWHIILGGAMLLMLT 241
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Mouse
Match: Emc10 (ER membrane protein complex subunit 10 [Source:MGI Symbol;Acc:MGI:1916933])

HSP 1 Score: 92.4337 bits (228), Expect = 1.060e-21
Identity = 62/217 (28.57%), Postives = 105/217 (48.39%), Query Frame = 3 
Query:  144 ALGYEGENLDISSMNIEHSFTTNEE--------LVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIA---GT--NSE---FIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMP 734
            A G E E     ++ +EHSF   +         L+W  +      ++++   QLS E      E+  ++     NG Y++R+    GT   SE    + + +  C L+ S+    L + VD  GNVVGL +      C     ED D+E      T+  L+ P     P  + +++RLE+++ +K K+ Q + KSF +KYW Y++P+V+ L+M+  P
Sbjct:   41 ADGREAEGCGTVALLLEHSFELGDGANFQKRGLLLWNQQDG----TLSATQRQLSEE------ERGRLRDVAAVNGLYRVRVPRRPGTLDGSEAGGHVSSFVPACSLVESHLSDQLTLHVDVAGNVVGLSVVVYPGGCRGSEVEDEDLEL---FNTSVQLRPPSTAPGPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWMYIIPVVLFLMMSGAP 243
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Mouse
Match: Emc10 (ER membrane protein complex subunit 10 [Source:MGI Symbol;Acc:MGI:1916933])

HSP 1 Score: 92.4337 bits (228), Expect = 1.215e-21
Identity = 62/217 (28.57%), Postives = 105/217 (48.39%), Query Frame = 3 
Query:  144 ALGYEGENLDISSMNIEHSFTTNEE--------LVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIA---GT--NSE---FIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMP 734
            A G E E     ++ +EHSF   +         L+W  +      ++++   QLS E      E+  ++     NG Y++R+    GT   SE    + + +  C L+ S+    L + VD  GNVVGL +      C     ED D+E      T+  L+ P     P  + +++RLE+++ +K K+ Q + KSF +KYW Y++P+V+ L+M+  P
Sbjct:   51 ADGREAEGCGTVALLLEHSFELGDGANFQKRGLLLWNQQDG----TLSATQRQLSEE------ERGRLRDVAAVNGLYRVRVPRRPGTLDGSEAGGHVSSFVPACSLVESHLSDQLTLHVDVAGNVVGLSVVVYPGGCRGSEVEDEDLEL---FNTSVQLRPPSTAPGPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWMYIIPVVLFLMMSGAP 253
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Mouse
Match: Emc10 (ER membrane protein complex subunit 10 [Source:MGI Symbol;Acc:MGI:1916933])

HSP 1 Score: 76.2554 bits (186), Expect = 8.649e-16
Identity = 58/211 (27.49%), Postives = 98/211 (46.45%), Query Frame = 3 
Query:  144 ALGYEGENLDISSMNIEHSFTTNEE--------LVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIA---GT--NSE---FIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIML 716
            A G E E     ++ +EHSF   +         L+W  +      ++++   QLS E      E+  ++     NG Y++R+    GT   SE    + + +  C L+ S+    L + VD  GNVVGL +      C     ED D+E      T+  L+ P     P  + +++RLE+++ +K K+ Q + KSF +KYW  +L   ++L
Sbjct:   41 ADGREAEGCGTVALLLEHSFELGDGANFQKRGLLLWNQQDG----TLSATQRQLSEE------ERGRLRDVAAVNGLYRVRVPRRPGTLDGSEAGGHVSSFVPACSLVESHLSDQLTLHVDVAGNVVGLSVVVYPGGCRGSEVEDEDLEL---FNTSVQLRPPSTAPGPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWHLILGGAVLL 237
[Close]
BLAST of ER membrane protein complex subunit 10 vs. UniProt/SwissProt
Match: sp|A1A4M2|EMC10_BOVIN (ER membrane protein complex subunit 10 OS=Bos taurus OX=9913 GN=EMC10 PE=2 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 1.901e-24
Identity = 60/207 (28.99%), Postives = 106/207 (51.21%), Query Frame = 3 
Query:  150 GYEGENLDISSMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRI-----AGTNSE---FIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMP 734
            G EGE      + +EHSF  ++   +  + +L + +    ++ LS +  L   E+  ++     NG Y++R+     A    E   ++ + +  C L+ S+    L + VD  GNVVG+ + T    C     ED D+E      T+  LQ PV    P  + +++RLE+++ +K K+ Q + KSF +KYW Y++P+V+ L+M+  P
Sbjct:   43 GREGEGCGTVGLLLEHSFEIDDSAHFRKRGSL-LWNQQDGTLSLS-QRQLNEEERGRLRDVAALNGLYRVRVPRRPGAPDGPEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTYPGGCRGHEVEDVDLEL---FNTSVQLQPPVTAPGPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWMYIVPVVLFLMMSGAP 243
[Close]
BLAST of ER membrane protein complex subunit 10 vs. UniProt/SwissProt
Match: sp|A5D8P8|EMC10_XENLA (ER membrane protein complex subunit 10 OS=Xenopus laevis OX=8355 GN=emc10 PE=2 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.353e-23
Identity = 58/203 (28.57%), Postives = 112/203 (55.17%), Query Frame = 3 
Query:  150 GYEGENLDISSMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIA---GTN---SEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTS 728
            G E E+   +++ +EHSF  ++ + +  + +L        SI +  +  LT +E+  ++     NG Y+IRI    G +   +E++ + ++ C ++ S+    + V  D  GNV+G+ + T   +C+    ED D+E      TT H+Q P+    P  + +++RLE+++ +K K+ Q + KSF +KYW Y++P+V+ L+M+ 
Sbjct:   50 GRESESCG-TNLELEHSFELDDSIDFKKRGSLFWSGTAEQSISIL-QKQLTEDERNKLRDIANLNGLYRIRIPRKLGISEEVNEYVTSFVRACSMVESHLSDEITVHTDISGNVIGVSIVTFPGSCNGAEVEDVDLEM---FNTTVHIQQPIAAAVPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWMYIIPVVLFLMMSG 246
[Close]
BLAST of ER membrane protein complex subunit 10 vs. UniProt/SwissProt
Match: sp|Q6P7K5|EMC10_XENTR (ER membrane protein complex subunit 10 OS=Xenopus tropicalis OX=8364 GN=emc10 PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 8.594e-23
Identity = 53/194 (27.32%), Postives = 106/194 (54.64%), Query Frame = 3 
Query:  177 SSMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGT------NSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTS 728
            +++ +EHSF  ++ + +  + +L        SI +  +  LT +E+  ++     NG Y+IR+          +E++ + ++ C ++ S+    + V  D  GNVVG+ + T   +C+    ED D+E      TT ++Q P+    P  + +++RLE+++ +K K+ Q + KSF +KYW Y++P+V+ L+M+ 
Sbjct:   54 TNLELEHSFELDDSIHFKKRGSLIWSGTAEQSISIL-QKQLTEDERNKLRDIANLNGLYRIRVPRKLGITEEANEYVTSFVRACSMVESHLSDQISVHTDISGNVVGISIVTFPGSCNGAEVEDVDLEM---FNTTVYIQQPIAAAVPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWMYIIPVVLFLMMSG 242
[Close]
BLAST of ER membrane protein complex subunit 10 vs. UniProt/SwissProt
Match: sp|Q6AYH6|EMC10_RAT (ER membrane protein complex subunit 10 OS=Rattus norvegicus OX=10116 GN=Emc10 PE=1 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 1.435e-22
Identity = 63/217 (29.03%), Postives = 107/217 (49.31%), Query Frame = 3 
Query:  144 ALGYEGENLDISSMNIEHSFTTNE--------ELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIA---GT--NSE---FIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMP 734
            A G+E E     ++ +EHSF   +         L+W  +      ++++   QLS E      E+  ++     NG Y++R+    GT   SE    + + +  C L+ S+    L + VD  GNVVGL +      C     ED D+E      T+ HL+ P     P  + +++RLE+++ +K K+ Q + KSF +KYW Y++P+V+ L+M+  P
Sbjct:   41 ADGHEAEGCGTVALLLEHSFEIGDGANFQKRGSLLWNQQDG----TLSATQRQLSEE------ERGRLRDVAAVNGLYRVRVPRRPGTLDGSEAGGHVSSFVPACSLVESHLSDQLTLHVDVAGNVVGLSVVVYPGGCRGSEVEDEDLEL---FNTSVHLRPPGTAPGPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWMYIIPVVLFLMMSGAP 243
[Close]
BLAST of ER membrane protein complex subunit 10 vs. UniProt/SwissProt
Match: sp|Q5UCC4|EMC10_HUMAN (ER membrane protein complex subunit 10 OS=Homo sapiens OX=9606 GN=EMC10 PE=1 SV=1)

HSP 1 Score: 95.5153 bits (236), Expect = 5.956e-22
Identity = 54/194 (27.84%), Postives = 99/194 (51.03%), Query Frame = 3 
Query:  189 IEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSE--------FIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMP 734
            +EHSF  ++   +  + +L + +    ++ LS +  L+  E+  ++     NG Y++RI              ++ + +  C L+ S+    L + VD  GNVVG+ + T    C     ED D+E      T+  LQ P     P  + +++RLE+++ +K K+ Q + KSF +KYW Y++P+V+ L+M+  P
Sbjct:   56 LEHSFEIDDSANFRKRGSL-LWNQQDGTLSLS-QRQLSEEERGRLRDVAALNGLYRVRIPRRPGALDGLEAGGYVSSFVPACSLVESHLSDQLTLHVDVAGNVVGVSVVTHPGGCRGHEVEDVDLEL---FNTSVQLQPPTTAPGPETAAFIERLEMEQAQKAKNPQ-EQKSFFAKYWMYIIPVVLFLMMSGAP 243
[Close]
BLAST of ER membrane protein complex subunit 10 vs. TrEMBL
Match: C1LFS2 (ER membrane protein complex subunit 10 isoform 1 OS=Schistosoma japonicum OX=6182 GN=EWB00_006255 PE=2 SV=1)

HSP 1 Score: 129.028 bits (323), Expect = 1.306e-32
Identity = 74/225 (32.89%), Postives = 129/225 (57.33%), Query Frame = 3 
Query:   84 MFIYHSIIMKIILSFLIFNFALGYEGENLDISSMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQL-SNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSV----EIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQDA 743
            MF+   +++ ++LS +            LD+S    EHSF   ++ V+T    + ++ I+S  + L S+ +  T+NEK+++ +S K++  Y +RI   N E+IE S+++CQ+I+S   V   VSV+  G+ + + +ST   NC   +D+ ++     ++  T  LQ P +G SP  + YL++LE Q  E  ++EQ DN+SF SKYW Y++P V + ++ S  QD 
Sbjct:    1 MFMVFHVLVSLVLSSI----------SALDVSDYKPEHSF---KDGVFTKMDGIVLK-ISSGELNLVSSSHVFTDNEKQSLLESAKASNMYSVRIPVRNDEYIEASIQSCQIIASRMRVKFTVSVNDLGDPIAIHMSTPKYNC--PYDISTNYLNLPDLSITLELQKPKLGSSPETAKYLEKLEKQREEMARAEQSDNRSFFSKYWTYIIPAVFLFILFSSMQDP 209
[Close]
BLAST of ER membrane protein complex subunit 10 vs. TrEMBL
Match: Q5DDX7 (SJCHGC09026 protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 127.487 bits (319), Expect = 4.790e-32
Identity = 72/225 (32.00%), Postives = 129/225 (57.33%), Query Frame = 3 
Query:   84 MFIYHSIIMKIILSFLIFNFALGYEGENLDISSMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQL-SNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSV----EIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQDA 743
            MF+   +++ ++LS +            LD+S    EHSF   ++ ++T    + ++ I+S  + L S+ +  T++EK+++ +S K++  Y +RI   N E+IE S+++CQ+I+S   V   VSV+  G+ + + +ST   NC   +D+ ++     ++  T  LQ P +G SP  + YL++LE Q  E  ++EQ DN+SF SKYW Y++P V + ++ S  QD 
Sbjct:    1 MFVVFHVLVSLVLSSI----------SALDVSDYKPEHSF---KDGIFTKMDGIVLK-ISSGELNLVSSSHVFTDDEKQSLLESAKASNMYSVRIPVRNDEYIEASIQSCQIIASRMRVKFTVSVNDLGDPIAIHMSTPKYNC--PYDISTNYLNLPDLSITLELQKPKLGSSPETAKYLEKLEKQREEMARAEQSDNRSFFSKYWTYIIPAVFLFILFSSMQDP 209
[Close]
BLAST of ER membrane protein complex subunit 10 vs. TrEMBL
Match: A0A3Q0KIG7 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 4.312e-31
Identity = 67/219 (30.59%), Postives = 122/219 (55.71%), Query Frame = 3 
Query:  105 IMKIILSFLIFNFALGYEGENLDISSMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSV----EIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQDAAA 749
            ++ ++LS L+   +       LD+S    EH F  N   +++    ++I+S +     +S  +  + +EK+ +Q+S ++   Y +R+   N E+IE S+++CQ+ISS   + L VSV+  G+ V + +ST   +C   +D+  S     ++  +  +Q P +G SP  + YL++LE Q  E  ++EQ DN+SF +KYW Y++P V + ++ S  QD  A
Sbjct:    1 MLPLVLSILLSPVS------TLDVSGYTPEHRFRENG--IFSQMDGISIKSSSGVLTLVSGGHVFSTDEKQQLQESARAGYMYSVRMPVKNEEYIEASIRSCQIISSRMRLKLTVSVNDAGDPVAIHMSTPKYDC--SYDISESFLDLPDLSISLTVQKPKLGPSPETAKYLEKLEKQREEMARAEQSDNRSFFAKYWTYIIPAVFLFILFSSMQDPNA 209
[Close]
BLAST of ER membrane protein complex subunit 10 vs. TrEMBL
Match: D3TRN5 (Hypothetical conserved protein OS=Glossina morsitans morsitans OX=37546 PE=2 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 4.312e-31
Identity = 67/219 (30.59%), Postives = 122/219 (55.71%), Query Frame = 3 
Query:  105 IMKIILSFLIFNFALGYEGENLDISSMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSV----EIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQDAAA 749
            ++ ++LS L+   +       LD+S    EH F  N   +++    ++I+S +     +S  +  + +EK+ +Q+S ++   Y +R+   N E+IE S+++CQ+ISS   + L VSV+  G+ V + +ST   +C   +D+  S     ++  +  +Q P +G SP  + YL++LE Q  E  ++EQ DN+SF +KYW Y++P V + ++ S  QD  A
Sbjct:    1 MLPLVLSILLSPVS------TLDVSGYTPEHRFRENG--IFSQMDGISIKSSSGVLTLVSGGHVFSTDEKQQLQESARAGYMYSVRMPVKNEEYIEASIRSCQIISSRMRLKLTVSVNDAGDPVAIHMSTPKYDC--SYDISESFLDLPDLSISLTVQKPKLGPSPETAKYLEKLEKQREEMARAEQSDNRSFFAKYWTYIIPAVFLFILFSSMQDPNA 209
[Close]
BLAST of ER membrane protein complex subunit 10 vs. TrEMBL
Match: G4LVW9 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 GN=Smp_083970 PE=4 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 8.503e-28
Identity = 55/161 (34.16%), Postives = 96/161 (59.63%), Query Frame = 3 
Query:  279 LSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSV----EIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQDAAA 749
            +S  +  + +EK+ +Q+S ++   Y +R+   N E+IE S+++CQ+ISS   + L VSV+  G+ V + +ST   +C   +D+  S     ++  +  +Q P +G SP  + YL++LE Q  E  ++EQ DN+SF +KYW Y++P V + ++ S  QD  A
Sbjct:   16 VSGGHVFSTDEKQQLQESARAGYMYSVRMPVKNEEYIEASIRSCQIISSRMRLKLTVSVNDAGDPVAIHMSTPKYDCS--YDISESFLDLPDLSISLTVQKPKLGPSPETAKYLEKLEKQREEMARAEQSDNRSFFAKYWTYIIPAVFLFILFSSMQDPNA 174
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Cavefish
Match: emc10 (ER membrane protein complex subunit 10 [Source:NCBI gene;Acc:103028842])

HSP 1 Score: 77.7962 bits (190), Expect = 1.609e-16
Identity = 50/199 (25.13%), Postives = 105/199 (52.76%), Query Frame = 3 
Query:  180 SMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSE-----------FIETSLKTCQLISSNF--IVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSVEIK---TTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTS 728
            S+ +EHSF  ++   +  +  + +++   N++ LS +  L+  ++  ++     +G Y+IRI   + +           ++   ++ C L+ S+   ++ L   V GF  V+G+ + T    C    +VE  V+++   TT  + +PV   +P  + +++R+E QE +K K +  + KSF +KYW Y++P+V+ L+M+ 
Sbjct:   44 SVPLEHSFEVDDVPRFWVRGNIQLKAGRENNVFLS-QAMLSEKDRSVLKDVAAVDGLYRIRIPRVSLQADRQTDRQLEGYLTAFVRACSLVESHLSDVITLHTDVSGF--VIGVSIVTMPGACR-GAEVEDEVDLEVFNTTISVMAPVNAPAPETALFIERME-QEMDK-KGKPQEQKSFFAKYWMYIVPLVLFLMMSG 236
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Cavefish
Match: emc10 (ER membrane protein complex subunit 10 [Source:NCBI gene;Acc:103028842])

HSP 1 Score: 72.0182 bits (175), Expect = 1.602e-14
Identity = 51/206 (24.76%), Postives = 104/206 (50.49%), Query Frame = 3 
Query:  180 SMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSE-----------FIETSLKTCQLISSNF--IVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSVEIK---TTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQDAAA 749
            S+ +EHSF  ++   +  +  + +++   N++ LS +  L+  ++  ++     +G Y+IRI   + +           ++   ++ C L+ S+   ++ L   V GF  V+G+ + T    C    +VE  V+++   TT  + +PV   +P  + +++R+E QE +K K +  + KSF +KYW+ +L   + L+ TS  Q  A 
Sbjct:   44 SVPLEHSFEVDDVPRFWVRGNIQLKAGRENNVFLS-QAMLSEKDRSVLKDVAAVDGLYRIRIPRVSLQADRQTDRQLEGYLTAFVRACSLVESHLSDVITLHTDVSGF--VIGVSIVTMPGACR-GAEVEDEVDLEVFNTTISVMAPVNAPAPETALFIERME-QEMDK-KGKPQEQKSFFAKYWYLILGGAVFLMATSSAQPPAG 243
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Sea Lamprey
Match: emc10 (ER membrane protein complex subunit 10 [Source:NCBI gene;Acc:565829])

HSP 1 Score: 95.1301 bits (235), Expect = 6.464e-24
Identity = 55/209 (26.32%), Postives = 110/209 (52.63%), Query Frame = 3 
Query:  150 GYEGENLDISSMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIA------GTNSEFIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCH----EDFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQDAA 746
            G E EN  + S+ +EHSF  +  + +  + T+  R    +++ +S +   T++E+  +++  + +G Y+IR+       G+++E++ T ++ C L+ +     L + +D  G + G+ L      CH    ED D+E+     T          + P  + Y++RLE ++ ++ K+ Q + KSF +KYW Y++P+V+ L+M+   QD  
Sbjct:    5 GIEVEN-GVVSLPLEHSFEVDGSVQFRRRGTVIWRPQREHAVSIS-QPPFTDDERNKLREVAEVDGLYRIRLPIPMGGDGSSTEYVFTFVRACALLEAQLSDLLTLHLDAVGAIAGISLEVVPGGCHGYEVEDVDLETFNTTLTVTTPVV---LLGPETASYIQRLEQEQAQRTKNPQ-EQKSFFAKYWMYIIPVVLFLIMSGA-QDPG 206
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Nematostella
Match: EDO36370 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIV5])

HSP 1 Score: 70.0922 bits (170), Expect = 3.521e-15
Identity = 40/119 (33.61%), Postives = 62/119 (52.10%), Query Frame = 3 
Query:  399 LKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCHE-----DFDVESSVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQD 740
            +K C L  SN    + +SVD  G V G+ L      C +      FD  +     TT  +     G  P+   Y++R+E ++R++   +  DN+SFL+KYW Y++PIVI +LM+S   D
Sbjct:    2 VKACSLYESNLTELITLSVDHLGYVYGVGLRPLVAGCSDKAYKPGFDGVTPF-FNTTVQILYQSNGPLPDTQTYVQRMEKEKRDQAGGKGKDNRSFLAKYWMYIVPIVIFMLMSSQQPD 119
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Medaka
Match: emc10 (ER membrane protein complex subunit 10 [Source:NCBI gene;Acc:101169536])

HSP 1 Score: 80.4925 bits (197), Expect = 1.898e-17
Identity = 50/199 (25.13%), Postives = 105/199 (52.76%), Query Frame = 3 
Query:  180 SMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRI------AGTNSEF-----IETSLKTCQLISSNF--IVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSVEIK---TTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTS 728
            S+ +EHSF  ++   +  + +L +++    S+ L N+N L+  ++  +++    +G Y+IR+      A   +E+     +   ++ C ++ S+   ++ L   V G+  ++G+ + T    C    +VE  V+++   TT  + +PV    P  + +++R+E QE EK      + KSF +KYW Y++P+V+ L+M+ 
Sbjct:   44 SVPLEHSFELDDVAKFQLRGSLMLKTGREPSVSL-NQNQLSEEDRTKLKEVAAVDGLYRIRVPRVFLQADKQTEWQSEGHLTAFVRACAMVESHLSDVITLHTDVSGY--LIGVSIVTLPGACR-GIEVEDEVDLEVFNTTLSIMAPVNAPGPETALFIQRME-QEFEKKGKNPQEQKSFFAKYWMYIVPLVLFLMMSG 237
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Medaka
Match: emc10 (ER membrane protein complex subunit 10 [Source:NCBI gene;Acc:101169536])

HSP 1 Score: 73.559 bits (179), Expect = 3.955e-15
Identity = 50/206 (24.27%), Postives = 105/206 (50.97%), Query Frame = 3 
Query:  180 SMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRI------AGTNSEF-----IETSLKTCQLISSNF--IVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSVEIK---TTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQDAAA 749
            S+ +EHSF  ++   +  + +L +++    S+ L N+N L+  ++  +++    +G Y+IR+      A   +E+     +   ++ C ++ S+   ++ L   V G+  ++G+ + T    C    +VE  V+++   TT  + +PV    P  + +++R+E QE EK      + KSF +KYW+ +L   I L++++  Q  A 
Sbjct:   23 SVPLEHSFELDDVAKFQLRGSLMLKTGREPSVSL-NQNQLSEEDRTKLKEVAAVDGLYRIRVPRVFLQADKQTEWQSEGHLTAFVRACAMVESHLSDVITLHTDVSGY--LIGVSIVTLPGACR-GIEVEDEVDLEVFNTTLSIMAPVNAPGPETALFIQRME-QEFEKKGKNPQEQKSFFAKYWYLILGGAIFLMVSNSAQPPAG 223
[Close]
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Medaka
Match: emc10 (ER membrane protein complex subunit 10 [Source:NCBI gene;Acc:101169536])

HSP 1 Score: 73.1738 bits (178), Expect = 7.248e-15
Identity = 50/206 (24.27%), Postives = 105/206 (50.97%), Query Frame = 3 
Query:  180 SMNIEHSFTTNEELVWTHKSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRI------AGTNSEF-----IETSLKTCQLISSNF--IVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVESSVEIK---TTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKYWFYLLPIVIMLLMTSMPQDAAA 749
            S+ +EHSF  ++   +  + +L +++    S+ L N+N L+  ++  +++    +G Y+IR+      A   +E+     +   ++ C ++ S+   ++ L   V G+  ++G+ + T    C    +VE  V+++   TT  + +PV    P  + +++R+E QE EK      + KSF +KYW+ +L   I L++++  Q  A 
Sbjct:   44 SVPLEHSFELDDVAKFQLRGSLMLKTGREPSVSL-NQNQLSEEDRTKLKEVAAVDGLYRIRVPRVFLQADKQTEWQSEGHLTAFVRACAMVESHLSDVITLHTDVSGY--LIGVSIVTLPGACR-GIEVEDEVDLEVFNTTLSIMAPVNAPGPETALFIQRME-QEFEKKGKNPQEQKSFFAKYWYLILGGAIFLMVSNSAQPPAG 244
The following BLAST results are available for this feature:
BLAST of ER membrane protein complex subunit 10 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
EMC101.240e-2227.84ER membrane protein complex subunit 10 [Source:HGN... [more]
EMC102.244e-2127.84ER membrane protein complex subunit 10 [Source:HGN... [more]
EMC101.322e-1626.60ER membrane protein complex subunit 10 [Source:HGN... [more]
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BLAST of ER membrane protein complex subunit 10 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Y43F8C.77.067e-829.51pep chromosome:WBcel235:V:19641296:19644030:-1 gen... [more]
Y43F8C.77.067e-829.51pep chromosome:WBcel235:V:19641292:19644083:-1 gen... [more]
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BLAST of ER membrane protein complex subunit 10 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
CG324414.379e-1023.76gene:FBgn0052441 transcript:FBtr0300058[more]
CG324415.844e-1023.76gene:FBgn0052441 transcript:FBtr0300057[more]
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BLAST of ER membrane protein complex subunit 10 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
emc101.729e-2126.13ER membrane protein complex subunit 10 [Source:NCB... [more]
emc106.655e-1925.74ER membrane protein complex subunit 10 [Source:NCB... [more]
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BLAST of ER membrane protein complex subunit 10 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2
Match NameE-valueIdentityDescription
emc101.622e-2327.32ER membrane protein complex subunit 10 [Source:NCB... [more]
emc101.234e-1926.42ER membrane protein complex subunit 10 [Source:NCB... [more]
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BLAST of ER membrane protein complex subunit 10 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Emc101.060e-2128.57ER membrane protein complex subunit 10 [Source:MGI... [more]
Emc101.215e-2128.57ER membrane protein complex subunit 10 [Source:MGI... [more]
Emc108.649e-1627.49ER membrane protein complex subunit 10 [Source:MGI... [more]
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BLAST of ER membrane protein complex subunit 10 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|A1A4M2|EMC10_BOVIN1.901e-2428.99ER membrane protein complex subunit 10 OS=Bos taur... [more]
sp|A5D8P8|EMC10_XENLA2.353e-2328.57ER membrane protein complex subunit 10 OS=Xenopus ... [more]
sp|Q6P7K5|EMC10_XENTR8.594e-2327.32ER membrane protein complex subunit 10 OS=Xenopus ... [more]
sp|Q6AYH6|EMC10_RAT1.435e-2229.03ER membrane protein complex subunit 10 OS=Rattus n... [more]
sp|Q5UCC4|EMC10_HUMAN5.956e-2227.84ER membrane protein complex subunit 10 OS=Homo sap... [more]
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BLAST of ER membrane protein complex subunit 10 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
C1LFS21.306e-3232.89ER membrane protein complex subunit 10 isoform 1 O... [more]
Q5DDX74.790e-3232.00SJCHGC09026 protein OS=Schistosoma japonicum OX=61... [more]
A0A3Q0KIG74.312e-3130.59Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
D3TRN54.312e-3130.59Hypothetical conserved protein OS=Glossina morsita... [more]
G4LVW98.503e-2834.16Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
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BLAST of ER membrane protein complex subunit 10 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
emc101.609e-1625.13ER membrane protein complex subunit 10 [Source:NCB... [more]
emc101.602e-1424.76ER membrane protein complex subunit 10 [Source:NCB... [more]
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BLAST of ER membrane protein complex subunit 10 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
emc106.464e-2426.32ER membrane protein complex subunit 10 [Source:NCB... [more]
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BLAST of ER membrane protein complex subunit 10 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of ER membrane protein complex subunit 10 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO363703.521e-1533.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of ER membrane protein complex subunit 10 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
emc101.898e-1725.13ER membrane protein complex subunit 10 [Source:NCB... [more]
emc103.955e-1524.27ER membrane protein complex subunit 10 [Source:NCB... [more]
emc107.248e-1524.27ER membrane protein complex subunit 10 [Source:NCB... [more]
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BLAST of ER membrane protein complex subunit 10 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 0
Match NameE-valueIdentityDescription
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026188 ID=SMED30026188|Name=ER membrane protein complex subunit 10|organism=Schmidtea mediterranea sexual|type=transcript|length=847bp
ATTTCTTTCAAATATAAGATTAATTCATTTGAAATTATATTTTTACTTTT
TAATTATATATTTATTACTCTCAATTACAATTAATGTTTATTTATCATTC
CATTATTATGAAAATCATTTTATCATTTTTAATTTTTAATTTTGCGTTAG
GTTATGAAGGCGAAAATCTAGATATATCATCTATGAATATTGAACATTCA
TTTACGACAAATGAAGAATTAGTTTGGACTCATAAATCTACGCTTAATAT
TAGATCAATAAACTCTAATTCAATTCAATTATCAAACGAAAACAGTCTCA
CCAATAATGAAAAGGAAAATATTCAAAAATCATTAAAATCAAATGGATTT
TATAAAATAAGAATTGCAGGAACTAACTCTGAATTTATCGAAACATCACT
TAAAACATGTCAATTGATTTCATCAAACTTTATCGTAAATTTGCAAGTTA
GCGTTGATGGGTTTGGTAATGTCGTTGGTTTATTTTTGAGCACTAAATCA
CAAAATTGCCATGAAGATTTTGATGTTGAAAGCTCAGTTGAAATTAAAAC
TACTGCTCACTTGCAAAGTCCAGTAATTGGTGTCAGTCCAAATATTTCTG
ACTATTTGAAAAGATTGGAAATTCAAGAACGCGAGAAAATGAAATCGGAA
CAAGGGGACAATAAATCTTTCTTGAGTAAATATTGGTTTTATTTGCTGCC
TATCGTGATTATGCTGTTGATGACTTCGATGCCGCAAGATGCAGCTGCAA
GATAATTGCGTTCGTTTTGTTCTATTCAAGTTTTTTTGTTAATATGTTAA
TTACGTTATGTATTTGTTGATAGAATAAATTTTGGGGCAGAAAAAAA
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protein sequence of SMED30026188-orf-1

>SMED30026188-orf-1 ID=SMED30026188-orf-1|Name=SMED30026188-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=224bp
MFIYHSIIMKIILSFLIFNFALGYEGENLDISSMNIEHSFTTNEELVWTH
KSTLNIRSINSNSIQLSNENSLTNNEKENIQKSLKSNGFYKIRIAGTNSE
FIETSLKTCQLISSNFIVNLQVSVDGFGNVVGLFLSTKSQNCHEDFDVES
SVEIKTTAHLQSPVIGVSPNISDYLKRLEIQEREKMKSEQGDNKSFLSKY
WFYLLPIVIMLLMTSMPQDAAAR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
GO:0072546ER membrane protein complex