Sorting nexin-27

Overview
NameSorting nexin-27
Smed IDSMED30026112
Length (bp)1771
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Sorting nexin-27 (SMED30026112) t-SNE clustered cells

Violin plots show distribution of expression levels for Sorting nexin-27 (SMED30026112) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Sorting nexin-27 (SMED30026112) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Sorting nexin-27 (SMED30026112) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30026112

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 13

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30026112h1SMcG0021891 Contig362GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Smed sexual biotypeSMED30026112h1SMcG0021892 Contig29848newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026112h1SMcG0021892 Contig29848uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026112h1SMcG0021891 Contig29848newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30026112h1SMcG0021891 Contig29848uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30026112h1SMcG0021891 dd_Smed_v4_2513_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30026112h1SMcG0021891 dd_Smed_v4_2513_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30026112h1SMcG0021891 dd_Smed_v4_2513_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30026112h1SMcG0021891 dd_Smed_v4_2513_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30026112h1SMcG0021891 dd_Smed_v4_2513_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30026112h1SMcG0021891 dd_Smed_v4_2513_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30026112h1SMcG0021891 dd_Smed_v4_2513_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30026112h1SMcG0021891 dd_Smed_v4_2513_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Sorting nexin-27 vs. Ensembl Human
Match: SNX27 (sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:20073])

HSP 1 Score: 336.265 bits (861), Expect = 3.512e-108
Identity = 195/485 (40.21%), Postives = 289/485 (59.59%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVN VNVEGATHKQVVDLI++G + LILTV+S    + +N+DPS DS   S  D+ E++ +PIS+P Y  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    E+ L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   41 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNHVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPRYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEI-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 516          
BLAST of Sorting nexin-27 vs. Ensembl Human
Match: SNX27 (sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:20073])

HSP 1 Score: 336.65 bits (862), Expect = 3.599e-108
Identity = 195/485 (40.21%), Postives = 289/485 (59.59%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVN VNVEGATHKQVVDLI++G + LILTV+S    + +N+DPS DS   S  D+ E++ +PIS+P Y  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    E+ L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   41 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNHVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPRYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEI-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 516          
BLAST of Sorting nexin-27 vs. Ensembl Human
Match: SNX27 (sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:20073])

HSP 1 Score: 192.586 bits (488), Expect = 5.866e-55
Identity = 110/355 (30.99%), Postives = 188/355 (52.96%), Query Frame = 2
Query:  416 FLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKI 1456
            + E++ +PIS+P Y  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    E+ L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI
Sbjct:   23 YTEKQAVPISVPRYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEI-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKI 368          
BLAST of Sorting nexin-27 vs. Ensembl Human
Match: SNX27 (sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:20073])

HSP 1 Score: 179.874 bits (455), Expect = 3.903e-50
Identity = 105/344 (30.52%), Postives = 178/344 (51.74%), Query Frame = 2
Query:  488 VYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            VYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    E+ L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   61 VYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEI-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 395          
BLAST of Sorting nexin-27 vs. Ensembl Human
Match: SNX27 (sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:20073])

HSP 1 Score: 104.375 bits (259), Expect = 7.821e-26
Identity = 51/64 (79.69%), Postives = 57/64 (89.06%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEV 268
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEV
Sbjct:   41 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEV 104          
BLAST of Sorting nexin-27 vs. Ensembl Celegans
Match: snx-27 (Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:Q93566])

HSP 1 Score: 259.61 bits (662), Expect = 1.373e-78
Identity = 175/495 (35.35%), Postives = 268/495 (54.14%), Query Frame = 2
Query:   74 KPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQHENIXX---XXXXXXXXXXXFLERRNLPISIPTYSMINEP-ESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRGNFYEKLPNDALS------ESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNY---LQLYRSLDVYAEIVFPACNSTAKKSGK-VIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLV---------TQDGKAKTRDVKITSISNKFLVEC 1489
            +P VV + KS++GFGFNV+GQV EGGQL+S+NG+LYAPLQ VSAVL  GAA++AGL K DRILEVNG+NVEG+TH++VVDLIK+GG+ L + VIS +  ++D      +SS     D+ E R+LP++IP+Y+ + +  E Y V+NIH++ + + SRRY E  + H  LK  F D+  P  P KWPF L+EQQL++RRR LEQYL  +C+ R IAES+LVQ  L +       D    +++++ LP+     ++  R+   S   +     +  + E       F    N +E+  +++ S       +++   S+ L LR++ F+   E  L K+     +  +V A  ++   K     K+     + R I +E N    L++ R L+ Y ++ FP      +K  + VI    F +L L+   D    E       WS I   R+ D      AF    +          Q    KT+ V++ +   +++ EC
Sbjct:   46 RPHVVKVVKSETGFGFNVKGQVSEGGQLRSLNGQLYAPLQHVSAVLRRGAADQAGLRKGDRILEVNGLNVEGSTHRKVVDLIKNGGDELTMIVISVEDPDMDRFDYGEESSMAYGHDYSENRSLPVTIPSYNTVQDSLERYTVFNIHMAGRQLGSRRYSEFVELHLALKKHFYDYCFPQLPGKWPFKLSEQQLDSRRRGLEQYLEKICTIRVIAESELVQKFLME------CDPMCEVEIRLMLPDGSPITIRTRRSITSSLFFTSAQRRLKMSREGAAACSIFELLDNSFERKVSESESVHELYTHNYSSASSSCLLLRKFIFDIDRERALCKRDMVFKQFCFVQAIADLHSGKVVTSRKSY----QLRAIQNEENMDELLEMARELEGYNQVTFPPSVCILRKRRQTVIMVVRFANLLLKCPEDGNSME-----IDWSRIKDFRVCDE---ATAFSFEYIRDEVGDSEQEQTEPRKTKYVRLETGFAEYMAEC 522          
BLAST of Sorting nexin-27 vs. Ensembl Celegans
Match: lin-7 (pep chromosome:WBcel235:II:14346877:14348792:-1 gene:WBGene00002996.1 transcript:Y54G11A.10a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-7)

HSP 1 Score: 63.1586 bits (152), Expect = 4.439e-11
Identity = 36/96 (37.50%), Postives = 55/96 (57.29%), Query Frame = 2
Query:   68 YKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKY-DRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 352
            +  PR+V +PK+  G GFNV G        K  N  +Y     +S ++P G A++ G LK  D+++ VNGVNVE   H++ VDL+KS   ++ L +
Sbjct:   87 HAHPRIVELPKTDQGLGFNVMGG-------KEQNSPIY-----ISRIIPGGVADRHGGLKRGDQLIAVNGVNVEAECHEKAVDLLKSAVGSVKLVI 170          
BLAST of Sorting nexin-27 vs. Ensembl Celegans
Match: lin-7 (pep chromosome:WBcel235:II:14347162:14348792:-1 gene:WBGene00002996.1 transcript:Y54G11A.10b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-7)

HSP 1 Score: 56.9954 bits (136), Expect = 5.241e-9
Identity = 35/96 (36.46%), Postives = 54/96 (56.25%), Query Frame = 2
Query:   68 YKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKY-DRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 352
            +  PR+V +PK+  G GFNV G        K  N  +Y     +S ++P G A++ G LK  D+++ VNG NVE   H++ VDL+KS   ++ L +
Sbjct:   87 HAHPRIVELPKTDQGLGFNVMGG-------KEQNSPIY-----ISRIIPGGVADRHGGLKRGDQLIAVNG-NVEAECHEKAVDLLKSAVGSVKLVI 169          
BLAST of Sorting nexin-27 vs. Ensembl Celegans
Match: shn-1 (pep chromosome:WBcel235:II:11384594:11390862:-1 gene:WBGene00006444.1 transcript:C33B4.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:shn-1)

HSP 1 Score: 57.3806 bits (137), Expect = 2.805e-8
Identity = 32/93 (34.41%), Postives = 51/93 (54.84%), Query Frame = 2
Query:   80 RVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS 358
            R+++IP+   GFGF +RG       L          LQ    V  +G A +AGL   D +LE++G++V   +H +VV+ I+  G+T+ L VI+
Sbjct:  435 RILVIPRGVKGFGFILRGAKHVAMPLNFEPTAQVPALQFFEGVDMSGMAVRAGLRPGDYLLEIDGIDVRRCSHDEVVEFIQQAGDTITLKVIT 527          
BLAST of Sorting nexin-27 vs. Ensembl Celegans
Match: shn-1 (pep chromosome:WBcel235:II:11384594:11390862:-1 gene:WBGene00006444.1 transcript:C33B4.3a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:shn-1)

HSP 1 Score: 57.3806 bits (137), Expect = 3.062e-8
Identity = 32/93 (34.41%), Postives = 51/93 (54.84%), Query Frame = 2
Query:   80 RVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS 358
            R+++IP+   GFGF +RG       L          LQ    V  +G A +AGL   D +LE++G++V   +H +VV+ I+  G+T+ L VI+
Sbjct:  435 RILVIPRGVKGFGFILRGAKHVAMPLNFEPTAQVPALQFFEGVDMSGMAVRAGLRPGDYLLEIDGIDVRRCSHDEVVEFIQQAGDTITLKVIT 527          
BLAST of Sorting nexin-27 vs. Ensembl Fly
Match: Snx27 (gene:FBgn0052758 transcript:FBtr0070843)

HSP 1 Score: 361.303 bits (926), Expect = 4.468e-118
Identity = 209/488 (42.83%), Postives = 287/488 (58.81%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQHENIXXXXXXXXXXXXXFL---ERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEE 1510
            PRVV I K+++GFGFNVRGQV EGGQL+SINGELYAPLQ VSAVL NGAAEKAG+ K DRILEVNGV+VEGATHKQVVDLIKSGG+ L LTVIS   +  D      D S   ++   ++R+LPISIP Y ++N   E Y+V+NIH++ + +CSRRYRE  + H+ L+  F  FN P  P KWPF L+EQQL+ RRR LEQYL  VC+ R IAESD VQ+ L D+       SA  +D+K+ LP++E+  + + ++ N   +        +       YF  F I   NF  KL     P+    ++++   ST L +RRW F+ A E+ L         +FY  A +E+     R D + L  L   ++     +YL L R+L  Y ++VFP C+  ++K G V+P    KS +L A  ++G  E  ++   W  I++    ++D   ++F       D  A  R VK+ +  + FL +C  R  EE
Sbjct:   46 PRVVTIYKTETGFGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLENGAAEKAGIKKGDRILEVNGVSVEGATHKQVVDLIKSGGDCLTLTVISVTQQEADRLEPQEDQSGYSYIDYSDKRSLPISIPDYGIVNRNGERYIVFNIHMAGRQLCSRRYREFANLHSLLRKEFSGFNFPKLPGKWPFQLSEQQLDTRRRGLEQYLEKVCAVRVIAESDAVQDFLTDTEDDI---SASPVDIKVMLPDHEVSTVSVKKSSNAQVVWEILVQRANLTAYTQQYFYLFEIVEYNFERKLQPHEIPHQLYVQNYSTASSTCLCVRRWLFSVAKELTLPDGEQAGRFIFY-QAVDEVNRGNIRADGR-LYELKALQDAKKAGDYLALARTLPGYGDVVFPHCSCDSRKEGHVVPAVGMKSFRLHACREDGSLEAQMVELTWDSITR---SESDEESMSFCFQYNRPDKPA--RWVKVYTPYHAFLADCFDRIMEE 523          
BLAST of Sorting nexin-27 vs. Ensembl Fly
Match: Snx27 (gene:FBgn0052758 transcript:FBtr0339525)

HSP 1 Score: 259.996 bits (663), Expect = 3.239e-80
Identity = 161/445 (36.18%), Postives = 240/445 (53.93%), Query Frame = 2
Query:  206 VLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQHENIXXXXXXXXXXXXXFLE---RRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEE 1510
            +LP  + + A L+  ++    NGV+VEGATHKQVVDLIKSGG+ L LTVIS   +  D      D S   +++   +R+LPISIP Y ++N   E Y+V+NIH++ + +CSRRYRE  + H+ L+  F  FN P  P KWPF L+EQQL+ RRR LEQYL  VC+ R IAESD VQ+ L D+       SA  +D+K+ LP++E+  + + ++ N   +        +       YF  F I   NF  KL     P+    ++++   ST L +RRW F+ A E+ L         +FY  A +E+     R D + L  L   ++     +YL L R+L  Y ++VFP C+  ++K G V+P    KS +L A  ++G  E  ++   W  I++    ++D   ++F       D  A  R VK+ +  + FL +C  R  EE
Sbjct:    1 MLPFHSVQYAQLMALEKRCLRNGVSVEGATHKQVVDLIKSGGDCLTLTVISVTQQEADRLEPQEDQSGYSYIDYSDKRSLPISIPDYGIVNRNGERYIVFNIHMAGRQLCSRRYREFANLHSLLRKEFSGFNFPKLPGKWPFQLSEQQLDTRRRGLEQYLEKVCAVRVIAESDAVQDFLTDTEDDI---SASPVDIKVMLPDHEVSTVSVKKSSNAQVVWEILVQRANLTAYTQQYFYLFEIVEYNFERKLQPHEIPHQLYVQNYSTASSTCLCVRRWLFSVAKELTLPDGEQAGRFIFY-QAVDEVNRGNIRADGR-LYELKALQDAKKAGDYLALARTLPGYGDVVFPHCSCDSRKEGHVVPAVGMKSFRLHACREDGSLEAQMVELTWDSITR---SESDEESMSFCFQYNRPDKPA--RWVKVYTPYHAFLADCFDRIMEE 435          
BLAST of Sorting nexin-27 vs. Ensembl Fly
Match: Snx27 (gene:FBgn0052758 transcript:FBtr0340670)

HSP 1 Score: 256.144 bits (653), Expect = 6.899e-79
Identity = 157/424 (37.03%), Postives = 230/424 (54.25%), Query Frame = 2
Query:  269 NGVNVEGATHKQVVDLIKSGGETLILTVISSQHENIXXXXXXXXXXXXXFLE---RRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEE 1510
            NGV+VEGATHKQVVDLIKSGG+ L LTVIS   +  D      D S   +++   +R+LPISIP Y ++N   E Y+V+NIH++ + +CSRRYRE  + H+ L+  F  FN P  P KWPF L+EQQL+ RRR LEQYL  VC+ R IAESD VQ+ L D+       SA  +D+K+ LP++E+  + + ++ N   +        +       YF  F I   NF  KL     P+    ++++   ST L +RRW F+ A E+ L         +FY  A +E+     R D + L  L   ++     +YL L R+L  Y ++VFP C+  ++K G V+P    KS +L A  ++G  E  ++   W  I++    ++D   ++F       D  A  R VK+ +  + FL +C  R  EE
Sbjct:    9 NGVSVEGATHKQVVDLIKSGGDCLTLTVISVTQQEADRLEPQEDQSGYSYIDYSDKRSLPISIPDYGIVNRNGERYIVFNIHMAGRQLCSRRYREFANLHSLLRKEFSGFNFPKLPGKWPFQLSEQQLDTRRRGLEQYLEKVCAVRVIAESDAVQDFLTDTEDDI---SASPVDIKVMLPDHEVSTVSVKKSSNAQVVWEILVQRANLTAYTQQYFYLFEIVEYNFERKLQPHEIPHQLYVQNYSTASSTCLCVRRWLFSVAKELTLPDGEQAGRFIFY-QAVDEVNRGNIRADGR-LYELKALQDAKKAGDYLALARTLPGYGDVVFPHCSCDSRKEGHVVPAVGMKSFRLHACREDGSLEAQMVELTWDSITR---SESDEESMSFCFQYNRPDKPA--RWVKVYTPYHAFLADCFDRIMEE 422          
BLAST of Sorting nexin-27 vs. Ensembl Fly
Match: Prosap (gene:FBgn0040752 transcript:FBtr0339763)

HSP 1 Score: 73.559 bits (179), Expect = 3.263e-13
Identity = 38/99 (38.38%), Postives = 59/99 (59.60%), Query Frame = 2
Query:   68 YKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQ 364
            Y  PR V++ +++ GFGF +RG       ++    E +  LQ +  V P G A+ AGL   D +L +NG +V  A+H+QVV++I+S G  + LTV+S Q
Sbjct:  557 YNAPRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVSPQ 655          
BLAST of Sorting nexin-27 vs. Ensembl Fly
Match: Prosap (gene:FBgn0040752 transcript:FBtr0087601)

HSP 1 Score: 73.9442 bits (180), Expect = 3.286e-13
Identity = 38/99 (38.38%), Postives = 59/99 (59.60%), Query Frame = 2
Query:   68 YKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQ 364
            Y  PR V++ +++ GFGF +RG       ++    E +  LQ +  V P G A+ AGL   D +L +NG +V  A+H+QVV++I+S G  + LTV+S Q
Sbjct:  703 YNAPRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVSPQ 801          
BLAST of Sorting nexin-27 vs. Ensembl Zebrafish
Match: snx27a (sorting nexin 27a [Source:ZFIN;Acc:ZDB-GENE-060503-371])

HSP 1 Score: 337.806 bits (865), Expect = 2.092e-108
Identity = 193/486 (39.71%), Postives = 287/486 (59.05%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRID-EKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG++K DRILEVNGV+VEGATHKQVVDLI++G   L+LTV+S    + + +D S + +     D+ +++ +PIS+PTY  + +  E +VVYN+++S + +CS+RYRE    H  LK  F ++  P  P KWPFSL+EQQL+ARRR LE+Y+  VCS R I ESD++Q  L +S +    +   +++L+I+LP+     +++ +N     +     + +  +  +  YF  F +   +F  KL     P+    +++   V  T L +R+W F+   E +L++   N   + Y   Q + + +K  I  E     L K  E      YL L RS + Y E+ FP C   +++ G VI   + K  +L A  ++G  E+ ++ F WS++ +    DTD   +AF    V   G+ K R VKI +    ++ EC  R
Sbjct:   44 PRVVRIIKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGIVKGDRILEVNGVSVEGATHKQVVDLIRAGERELVLTVLSIPAQEADGLDTSEEGAVQPNYDYSDKQAVPISVPTYKHVEQHSEKFVVYNVYMSGRQLCSKRYREFAILHQNLKREFSNYTFPKLPGKWPFSLSEQQLDARRRGLEEYMERVCSVRIIGESDIMQEFLSESNENH--NGITDVELRIALPDKTTASVRVQKNSTTDQVYQALVVKVGMDSMMASYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTMRKWLFSTQ-EEDLLR--DNPLALHYCFHQAQDDVKKGFIKAEDKAYQLQKLAEQRKMTTYLSLLRSCEGYNEVTFPHCPCDSRRKGHVITAVSMKHFKLHACTEDGTLENQVIMFEWSEMQRW---DTDEEGMAFCFEYVR--GEKKPRWVKIFTPYFNYMHECFER 519          
BLAST of Sorting nexin-27 vs. Ensembl Zebrafish
Match: snx27b (sorting nexin 27b [Source:ZFIN;Acc:ZDB-GENE-040426-1529])

HSP 1 Score: 329.717 bits (844), Expect = 2.682e-105
Identity = 192/485 (39.59%), Postives = 285/485 (58.76%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINEP-ESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PR+V I KS SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G + L+L V+S    + +++DP  D S  S  D+ +++ +PIS+PTY  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+I++P+     +++ +N     +       I  +     YF  F +    F  KL     P+    +++   V  T L LR+W F    E+ L      +   F+  A ++++    ++ EK+   L K  E      YL + R+ + Y EI FP C+  +++ G VI   + +  +L A  ++G  E+ +++F WS++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   46 PRLVRIVKSDSGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGISKGDRILEVNGVNVEGATHKQVVDLIRAGEKELVLAVLSVPQPETDSLDPGDDGSSQSCYDYSDKQAVPISVPTYKHVEQSGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFAFPKLPGKWPFSLSEQQLDARRRGLEEYLEKVCSVRVIGESDIMQEFLSESDEN--YNGVSDVELRIAMPDKTTVTVRVRKNCTTDQVYQAVVTKIGMDSITASYFALFEVINHTFARKLAPNEFPHKLYVQNYTSAVPGTCLTLRKWLFTTEEEILLNDNELAINYCFH-QALDDVKKGFIKVGEKS-YQLQKLTEQRKMTMYLSILRTCEGYNEITFPHCSCDSRRKGHVITAISIRHFKLHACTEDGTLENQVIAFDWSEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 521          
BLAST of Sorting nexin-27 vs. Ensembl Zebrafish
Match: snx17 (sorting nexin 17 [Source:NCBI gene;Acc:568263])

HSP 1 Score: 78.5666 bits (192), Expect = 6.155e-15
Identity = 59/260 (22.69%), Postives = 119/260 (45.77%), Query Frame = 2
Query:  479 SYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPR------GNFYEKLPNDALSESFACGVSTS---LFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPAC 1231
            SYV YNIH++  L C  RY +L   H Q+K  + +   P+FP K  F+L   +++ RR  LE+Y+  V     +  S++  + L  + + T     + + L+I L N +   + I  +    ++L   A  +   +E++ YF  F+ +        +  KL    L       + +S   + LR+ +++ A + +++     L  + Y    ++I+     ++++    L   +E   +  +++L ++L  Y  I F  C
Sbjct:   18 SYVAYNIHVNGVLHCRVRYSQLLGLHEQIKKEYGNNVVPAFPPKKIFTLTPAEVDQRREQLEKYMQAVRQDPILGSSEMFNSFLRKAQQETQQIPTEEVQLEIYLSNGQKVKVNILTSDQTEDVLEAVASKLDLPDELVGYFSLFLVQERADGSCTYVRKLQEFELPYVSITSLHSSDYRIILRKSYWDTAYDSDVMDDRVGLN-LLYAQTVSDIDRGWILVNKEQHRQLKSLQEKGSKKEFIRLAQTLKYYGYIKFDPC 276          
BLAST of Sorting nexin-27 vs. Ensembl Zebrafish
Match: snx17 (sorting nexin 17 [Source:NCBI gene;Acc:568263])

HSP 1 Score: 78.1814 bits (191), Expect = 7.584e-15
Identity = 59/260 (22.69%), Postives = 119/260 (45.77%), Query Frame = 2
Query:  479 SYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPR------GNFYEKLPNDALSESFACGVSTS---LFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPAC 1231
            SYV YNIH++  L C  RY +L   H Q+K  + +   P+FP K  F+L   +++ RR  LE+Y+  V     +  S++  + L  + + T     + + L+I L N +   + I  +    ++L   A  +   +E++ YF  F+ +        +  KL    L       + +S   + LR+ +++ A + +++     L  + Y    ++I+     ++++    L   +E   +  +++L ++L  Y  I F  C
Sbjct:   18 SYVAYNIHVNGVLHCRVRYSQLLGLHEQIKKEYGNNVVPAFPPKKIFTLTPAEVDQRREQLEKYMQAVRQDPILGSSEMFNSFLRKAQQETQQIPTEEVQLEIYLSNGQKVKVNILTSDQTEDVLEAVASKLDLPDELVGYFSLFLVQERADGSCTYVRKLQEFELPYVSITSLHSSDYRIILRKSYWDTAYDSDVMDDRVGLN-LLYAQTVSDIDRGWILVNKEQHRQLKSLQEKGSKKEFIRLAQTLKYYGYIKFDPC 276          
BLAST of Sorting nexin-27 vs. Ensembl Zebrafish
Match: slc9a3r1b (SLC9A3 regulator 1b [Source:ZFIN;Acc:ZDB-GENE-170530-6])

HSP 1 Score: 68.1662 bits (165), Expect = 7.516e-12
Identity = 42/111 (37.84%), Postives = 60/111 (54.05%), Query Frame = 2
Query:   26 SLDNLNNINAT-LDYYKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVI 355
             +DN+ ++    L    +PR+  I K  +GFGFN             ++ E   P Q + AV  +  AE++GL   DRI++VNGV+VEG  H QVV  IK+GGE   L V+
Sbjct:  144 GVDNIFSVGEKDLKLELRPRLCFIMKGSNGFGFN-------------LHSEKSRPGQFIRAVDEDSPAERSGLRPKDRIVQVNGVSVEGKQHAQVVSAIKAGGEETSLLVV 241          

HSP 2 Score: 56.9954 bits (136), Expect = 3.123e-8
Identity = 31/94 (32.98%), Postives = 51/94 (54.26%), Query Frame = 2
Query:   74 KPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVI 355
            +PR+ ++ K  +G+GF++ G+ G+ GQ              +  V P+  AE +GL   DR++ VNG  VE  +H+QVV  I+    +L L V+
Sbjct:    7 RPRLCVLEKGDTGYGFHLHGEKGKTGQF-------------IRLVEPDSPAEVSGLRAGDRLVFVNGARVEAESHQQVVARIRESTGSLELIVV 87          
BLAST of Sorting nexin-27 vs. Ensembl Xenopus
Match: SNX27 (sorting nexin family member 27 [Source:NCBI gene;Acc:100170579])

HSP 1 Score: 287.345 bits (734), Expect = 5.001e-91
Identity = 159/332 (47.89%), Postives = 218/332 (65.66%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVEL 1039
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G + L+LTV+S    + EN+DPS DSS  S  D+ E++ +PISIPTY  + +  E +VVYN++++ + +CS+RYRE    +  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+I+LP+     +++ +N     +       I  +    +YF  F +   +F  KL     P+    +++   V  T L +R+W F  + E  L
Sbjct:   26 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGIRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELVLTVLSVPPHEAENLDPSDDSSGQSFYDYTEKQAVPISIPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILNQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRIALPDKSTVTVRVKKNSTTDQVYQALTAKIGMDGITANYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTVRKWLFTTSEEALL 355          
BLAST of Sorting nexin-27 vs. Ensembl Xenopus
Match: chrnb3 (cholinergic receptor, nicotinic beta 3 [Source:Xenbase;Acc:XB-GENE-5793509])

HSP 1 Score: 68.1662 bits (165), Expect = 7.385e-12
Identity = 41/100 (41.00%), Postives = 55/100 (55.00%), Query Frame = 2
Query:   74 KPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQHEN 373
            +PR+  I K  SGFGFN             ++ +   P Q V AV P+  AE AGLL  DRI+EVNG+NV G  H  VV  IK+GG+   L V+  + ++
Sbjct:  115 RPRLCTIKKGPSGFGFN-------------LHSDKVHPGQFVRAVDPDSPAELAGLLPKDRIVEVNGLNVIGKQHGDVVAAIKAGGDETSLLVLDPEADS 201          

HSP 2 Score: 54.6842 bits (130), Expect = 1.891e-7
Identity = 35/97 (36.08%), Postives = 48/97 (49.48%), Query Frame = 2
Query:   80 RVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQHE 370
            RV ++ K  SG+GF+             ++ E   P Q V  V P  AAEKAGL   DR++ V G +V    H+QVV  I++  E L L V   + E
Sbjct:    5 RVCVLEKGDSGYGFH-------------LHSEKTRPGQYVRLVEPGSAAEKAGLRAGDRLIRVCGEDVRELGHQQVVSKIRAATEKLTLEVQGVEEE 88          
BLAST of Sorting nexin-27 vs. Ensembl Xenopus
Match: lin7a (lin-7 homolog A [Source:NCBI gene;Acc:100144984])

HSP 1 Score: 65.855 bits (159), Expect = 2.262e-11
Identity = 38/96 (39.58%), Postives = 57/96 (59.38%), Query Frame = 2
Query:   68 YKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKY-DRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 352
            +  PRVV +PK+  G GFNV G        K  N  +Y     +S ++P G AE+ G LK  D++L VNGV+VEG  H++ V+L+K+  +++ L V
Sbjct:  123 HSHPRVVELPKTDEGLGFNVMGG-------KEQNSPIY-----ISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVV 206          
BLAST of Sorting nexin-27 vs. Ensembl Xenopus
Match: lin7a (lin-7 homolog A [Source:NCBI gene;Acc:100144984])

HSP 1 Score: 66.2402 bits (160), Expect = 2.264e-11
Identity = 38/96 (39.58%), Postives = 57/96 (59.38%), Query Frame = 2
Query:   68 YKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKY-DRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 352
            +  PRVV +PK+  G GFNV G        K  N  +Y     +S ++P G AE+ G LK  D++L VNGV+VEG  H++ V+L+K+  +++ L V
Sbjct:  149 HSHPRVVELPKTDEGLGFNVMGG-------KEQNSPIY-----ISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVV 232          
BLAST of Sorting nexin-27 vs. Ensembl Xenopus
Match: ENSXETT00000028683.1 (lin-7 homolog B [Source:NCBI gene;Acc:100491827])

HSP 1 Score: 63.929 bits (154), Expect = 5.577e-11
Identity = 37/96 (38.54%), Postives = 56/96 (58.33%), Query Frame = 2
Query:   68 YKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKY-DRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 352
            +  PRVV +PK+  G GFN+ G        K  N  +Y     +S ++P G A++ G LK  D++L VNGV+VEG  H++ V+L+K+   T+ L V
Sbjct:   88 HAHPRVVELPKTDEGLGFNIMGG-------KEQNSPIY-----ISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGTVKLVV 171          
BLAST of Sorting nexin-27 vs. Ensembl Mouse
Match: Snx27 (sorting nexin family member 27 [Source:MGI Symbol;Acc:MGI:1923992])

HSP 1 Score: 343.969 bits (881), Expect = 3.008e-111
Identity = 198/485 (40.82%), Postives = 291/485 (60.00%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G + LILTV+S    + +N+DPS DS   S  D+ E++ +PIS+PTY  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    EV L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   39 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEV-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLHEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 514          
BLAST of Sorting nexin-27 vs. Ensembl Mouse
Match: Snx27 (sorting nexin family member 27 [Source:MGI Symbol;Acc:MGI:1923992])

HSP 1 Score: 343.969 bits (881), Expect = 3.835e-111
Identity = 198/485 (40.82%), Postives = 291/485 (60.00%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G + LILTV+S    + +N+DPS DS   S  D+ E++ +PIS+PTY  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    EV L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   39 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEV-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLHEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 514          
BLAST of Sorting nexin-27 vs. Ensembl Mouse
Match: Snx27 (sorting nexin family member 27 [Source:MGI Symbol;Acc:MGI:1923992])

HSP 1 Score: 240.35 bits (612), Expect = 1.333e-72
Identity = 147/421 (34.92%), Postives = 234/421 (55.58%), Query Frame = 2
Query:  269 NGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            NGVNVEGATHKQVVDLI++G + LILTV+S    + +N+DPS DS   S  D+ E++ +PIS+PTY  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    EV L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   12 NGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEV-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLHEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 423          
BLAST of Sorting nexin-27 vs. Ensembl Mouse
Match: Snx27 (sorting nexin family member 27 [Source:MGI Symbol;Acc:MGI:1923992])

HSP 1 Score: 106.301 bits (264), Expect = 6.510e-27
Identity = 49/94 (52.13%), Postives = 65/94 (69.15%), Query Frame = 2
Query:  476 ESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPV 757
            E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S + T V
Sbjct:    6 EKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDELTRV 99          
BLAST of Sorting nexin-27 vs. Ensembl Mouse
Match: Snx17 (sorting nexin 17 [Source:MGI Symbol;Acc:MGI:2387801])

HSP 1 Score: 83.5741 bits (205), Expect = 1.425e-16
Identity = 62/260 (23.85%), Postives = 120/260 (46.15%), Query Frame = 2
Query:  479 SYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRG------NFYEKLPNDALSESFACGVSTS---LFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPAC 1231
            +YV YNIH++  L C  RY +L   H QL+  +     P+FP K  FSL   ++E RR  LE+Y+  V     +  S+   + L  + + T     + + L++ L N +  L+ +  +    ++L   A  +   ++++ YF  F+ R       +F  KL    L       + +    + LR+ +++ A + ++++    L  + Y    ++IEH    + ++    L   +E   +  +L+L ++L  Y  + F AC
Sbjct:   19 AYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVVPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVTVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQEFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLN-LLYAQTVSDIEHGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDAC 277          
BLAST of Sorting nexin-27 vs. UniProt/SwissProt
Match: sp|Q3UHD6|SNX27_MOUSE (Sorting nexin-27 OS=Mus musculus OX=10090 GN=Snx27 PE=1 SV=2)

HSP 1 Score: 343.969 bits (881), Expect = 2.683e-110
Identity = 198/485 (40.82%), Postives = 291/485 (60.00%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G + LILTV+S    + +N+DPS DS   S  D+ E++ +PIS+PTY  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    EV L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   39 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEV-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLHEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 514          
BLAST of Sorting nexin-27 vs. UniProt/SwissProt
Match: sp|Q8K4V4|SNX27_RAT (Sorting nexin-27 OS=Rattus norvegicus OX=10116 GN=Snx27 PE=1 SV=2)

HSP 1 Score: 343.199 bits (879), Expect = 4.839e-110
Identity = 198/485 (40.82%), Postives = 291/485 (60.00%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G + LILTV+S    + +N+DPS DS   S  D+ E++ +PIS+PTY  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    EV L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   39 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGATVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEV-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 514          
BLAST of Sorting nexin-27 vs. UniProt/SwissProt
Match: sp|A5PKA5|SNX27_BOVIN (Sorting nexin-27 OS=Bos taurus OX=9913 GN=SNX27 PE=2 SV=1)

HSP 1 Score: 342.813 bits (878), Expect = 8.402e-110
Identity = 197/485 (40.62%), Postives = 291/485 (60.00%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G + LILTV+S    + +N+DPS DS   S  D+ E++ +PIS+PTY  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    E+ L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   41 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTIRKWLFTTEEEI-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 516          
BLAST of Sorting nexin-27 vs. UniProt/SwissProt
Match: sp|Q96L92|SNX27_HUMAN (Sorting nexin-27 OS=Homo sapiens OX=9606 GN=SNX27 PE=1 SV=2)

HSP 1 Score: 336.65 bits (862), Expect = 1.728e-107
Identity = 195/485 (40.21%), Postives = 289/485 (59.59%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PRVV I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVN VNVEGATHKQVVDLI++G + LILTV+S    + +N+DPS DS   S  D+ E++ +PIS+P Y  + +  E +VVYN++++ + +CS+RYRE    H  LK  F +F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+++LP+     +++ +N     +    A  +  +   ++YF  F +   +F  KL     P+    +++   V  T L +R+W F    E+ L+         F+  A ++++    + +EK+   L K  E      YL + R+ + Y EI+FP C   +++ G VI   +    +L A  +EG+ E+ +++F W ++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   41 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGVRKGDRILEVNHVNVEGATHKQVVDLIRAGEKELILTVLSVPPHEADNLDPSDDSLGQSFYDYTEKQAVPISVPRYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGKWPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDEN--YNGVSDVELRVALPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVISHSFVRKLAPNEFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEI-LLNDNDLAVTYFFHQAVDDVKKGYIKAEEKS-YQLQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLHACTEEGQLENQVIAFEWDEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 516          
BLAST of Sorting nexin-27 vs. UniProt/SwissProt
Match: sp|Q8BVL3|SNX17_MOUSE (Sorting nexin-17 OS=Mus musculus OX=10090 GN=Snx17 PE=1 SV=2)

HSP 1 Score: 83.5741 bits (205), Expect = 9.971e-16
Identity = 62/260 (23.85%), Postives = 120/260 (46.15%), Query Frame = 2
Query:  479 SYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRG------NFYEKLPNDALSESFACGVSTS---LFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPAC 1231
            +YV YNIH++  L C  RY +L   H QL+  +     P+FP K  FSL   ++E RR  LE+Y+  V     +  S+   + L  + + T     + + L++ L N +  L+ +  +    ++L   A  +   ++++ YF  F+ R       +F  KL    L       + +    + LR+ +++ A + ++++    L  + Y    ++IEH    + ++    L   +E   +  +L+L ++L  Y  + F AC
Sbjct:   19 AYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVVPAFPPKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLEVLLSNGQKVLVTVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQEFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLN-LLYAQTVSDIEHGWILVTKEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDAC 277          
BLAST of Sorting nexin-27 vs. TrEMBL
Match: A0A4Y2J9K8 (Sorting nexin-27 OS=Araneus ventricosus OX=182803 GN=Snx27 PE=4 SV=1)

HSP 1 Score: 382.104 bits (980), Expect = 7.440e-123
Identity = 222/488 (45.49%), Postives = 297/488 (60.86%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINEPESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKN-LLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEE 1510
            PRVV I K+++GFGFNVRGQV EGG LKSINGELYAPLQ VSAVL  GAAEKAG+ K DRILEVNG+NVEGATHKQVVDLIKSGG+ L LT+IS    + E ++PS DSS +S  D+ E+R+LPISIP Y+ + + E YVV+NI+++ + +CSRRYRE  + H  LK  FPDFN P  P KWPF+L++QQL+ARRR LEQYL  VC+ R IAE+D++Q  L D        SA  +DLKI LP++   ++ + +N     +       I  ++E+  YF  F I    F  KL     P++   ++++   ST L +RRW F  + E+EL +   N+   F+   Q   +  K +I   N L  L   ++   +  YL+L R LD Y EI FP CN  A+K G V+      +L+LQA  D+G  E  I+ F W  + +  +DD     ++F       D   K R VKI +    FL +C  R +EE
Sbjct:   35 PRVVTIYKTETGFGFNVRGQVSEGGPLKSINGELYAPLQHVSAVLKEGAAEKAGIRKGDRILEVNGINVEGATHKQVVDLIKSGGDKLTLTIISVTAQEAERLEPSDDSSGYSYIDYSEKRSLPISIPDYNWVEKGEKYVVFNIYMAGRHLCSRRYREFSNLHLNLKKEFPDFNFPKLPGKWPFTLSDQQLDARRRGLEQYLEKVCAVRVIAENDIMQEFLTDMDDENGGSSA-AVDLKILLPDHSTVIVNVRKNSTTDEVYQAVIEKIGLSKEVSKYFALFEIVEYGFERKLQSNEYPHNLYIQNYSTATSTCLLIRRWLFTLSKEIELTE--DNMAATFF-FWQAIDDVNKGQIKPGNKLYELKALQDSSRKLEYLKLARQLDGYGEISFPHCNCDARKEGHVVTTVGLTNLKLQACKDDGTLESQIIDFNWDTVKEWEVDDEG---MSFSFKYAPPD--KKPRYVKIFTPYYVFLYDCFERIQEE 513          
BLAST of Sorting nexin-27 vs. TrEMBL
Match: A0A2P6KRG2 (Snx27 OS=Nephila clavipes OX=2585209 GN=NCL1_31074 PE=4 SV=1)

HSP 1 Score: 377.867 bits (969), Expect = 3.835e-121
Identity = 219/488 (44.88%), Postives = 298/488 (61.07%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINEPESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKN-LLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEE 1510
            PRVV I K+++GFGFNVRGQV EGG LKSINGELYAPLQ VSAVL  GAAEKAG+ K DRILEVNG+NVEGATHKQVVDLIKSGG+ L LT+IS    + E ++PS DSS +S  D+ E+R+LPISIP Y+ + + + YVV+NI+++ + +CSRRYRE  + H  LK  FPDFN P  P KWPF+L++QQL+ARRR LEQYL  VC+ R IAE+D++Q  L D        SA  +DLKI LP++   ++ + +N     +       I  ++++  +F  F I    F  KL     P++   ++++   ST L +RRW F  + E+EL +   N+   F+   Q   +  K +I   N L  L   ++   +  YL+L R LD Y EI FP C+  A+K G V+      +L+LQA  D+G  E  I+ F W  I +  +DD     ++F       D   K R VKI +    FL +C +R +EE
Sbjct:   37 PRVVTIYKTETGFGFNVRGQVSEGGPLKSINGELYAPLQHVSAVLKEGAAEKAGIRKGDRILEVNGINVEGATHKQVVDLIKSGGDKLTLTIISVTAQEAERLEPSDDSSGYSYIDYSEKRSLPISIPDYNWVEKGDKYVVFNIYMAGRHLCSRRYREFSNLHLNLKKEFPDFNFPKLPGKWPFTLSDQQLDARRRGLEQYLEKVCAVRVIAENDIMQEFLTDMDDENGGSSA-AVDLKILLPDHSTIVVNVRKNSTTEEVYQAVIEKIGMSKDVSKFFALFEIVEYGFERKLQLNEYPHNLYIQNYSTATSTCLLIRRWLFTLSKEIELTE--DNMAATFF-FWQAIDDVNKGQIKPGNKLYELKALQDSSRKLEYLKLARQLDGYGEISFPHCSCDARKEGHVVTTVGLTNLKLQACKDDGTLESQIIDFNWETIKEWELDDEG---MSFSFKYAPPD--KKPRYVKILTPYYVFLYDCFVRIQEE 515          
BLAST of Sorting nexin-27 vs. TrEMBL
Match: A0A087UA66 (Sorting nexin-27 (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_19858 PE=4 SV=1)

HSP 1 Score: 374.785 bits (961), Expect = 4.005e-120
Identity = 222/509 (43.61%), Postives = 304/509 (59.72%), Query Frame = 2
Query:   29 LDNLNNINATLDYYKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINEPESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKN-LLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEESSRPM 1525
            +DN +NI    ++   PRVV I K+++GFGFNVRGQV EGG LKSINGELYAPLQ VSAVL  GAAEKAG+ K DRILEVNG+NVEGATHKQVVDLIKSGG+ L LT+IS    + E ++PS DSS +S  D+ E+R+LPISIP Y+ + + E +VV+NI+++ + +CSRRYRE  + H  LK  FPDFN P  P KWPF+L++QQL+ARRR LEQYL  VC+ R IAE+D++Q  L D        SA  +DLKI LP++    + + +N     +       I  ++E+  +F  F I    F  KL     P++   ++++   ST L +R+W F  + E+EL +   N+   F+   Q   +  K +I   N L  L   ++   +  YL+L R LD Y EI FP C   A+K G V+      + +LQA  D+G  E  I+ F W  + +  +DD     ++F       D   K R VKI +    FL +C +R +EE    M
Sbjct:   17 VDN-SNICDDNNFTTGPRVVTIYKTETGFGFNVRGQVSEGGPLKSINGELYAPLQHVSAVLKEGAAEKAGIRKGDRILEVNGINVEGATHKQVVDLIKSGGDKLTLTIISVTPQEAERLEPSDDSSGYSYIDYSEKRSLPISIPDYNWVEKGEKFVVFNIYMAGRHLCSRRYREFANLHMNLKKEFPDFNFPKLPGKWPFTLSDQQLDARRRGLEQYLEKVCAVRVIAENDIMQEFLTDMDDENGGSSA-AVDLKILLPDHSTVTVNVRKNSTTEEVYQAVIEKIGMSKEVSKFFALFEIVEYGFERKLQLNEYPHNLYIQNYSTATSTCLLIRKWLFTLSKEIELTE--DNMAATFF-FWQAIDDVNKGQIKPGNKLYELKALQDSSRKLEYLKLARQLDGYGEISFPHCACDARKEGHVVATVGLTNFKLQACKDDGTLESQIIDFNWETVKEWELDDEG---MSFSFKYAPPD--KKPRYVKIYTPYYVFLYDCFVRIQEERKWNM 515          
BLAST of Sorting nexin-27 vs. TrEMBL
Match: A0A4Y7NJ63 (EOG090X05ZS OS=Megafenestra aurita OX=2291010 GN=EOG090X05ZS PE=2 SV=1)

HSP 1 Score: 371.703 bits (953), Expect = 1.798e-118
Identity = 211/501 (42.12%), Postives = 308/501 (61.48%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVI---SSQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINEP-ESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLL--CDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEESSRPMPKICYN 1543
            PRVV I KS++GFGFNVRGQV EGGQL+SING+LYAPLQ VSAVL  GAA+KAG+LK DRILEVN ++VEG+THKQVVDLIKSGG+ L+LTVI   S + E ++P  +++ +S  D+ E+R+LPISIP Y + ++  + YVV++I+++ + + SRRY E  D HN LK  F  FN P  P KWPF+L+EQQL+ARRR LEQYL  VC+ R IAESD+VQ  L  CD  +    +    +DLK+ LP +E+  + + +     ++ +     I  +++ + YF  F I   NF  KL     P++  +++++   +T L LRRW F+P +E+ L+ +   ++   +    +E+ ++ H I  +NL  L   ++I+    YL L R    Y E+VFP C   A+K G VIP   F + +LQA  ++G  ++ ++ FGW  I    +DD     +AF L     D     R V+I +    ++ +C  R +EE +R   K  +N
Sbjct:   29 PRVVKIVKSETGFGFNVRGQVSEGGQLRSINGQLYAPLQHVSAVLKGGAADKAGILKGDRILEVNSISVEGSTHKQVVDLIKSGGDVLLLTVISVSSKEAERLEPHEETAGYSYIDYSEKRSLPISIPDYRLADKKNDKYVVFDIYMAGRHLTSRRYSEFVDLHNNLKKEFIGFNFPKLPGKWPFALSEQQLDARRRGLEQYLEKVCAVRVIAESDIVQEFLTDCDDDQ----NGLQKVDLKVLLPTHEVVSVTVCKTSTTLDVYNATVEKICLDKQSVQYFALFEIVEYNFERKLQVHEVPHNIYTQNYSTASATCLALRRWLFSPQVEL-LLARDELISAYLFWQTVDEV-NRGHVIAGENLYQLKAMQDINRRTEYLALARQSPGYGEVVFPHCGCDARKEGHVIPSLGFNAFRLQACKEDGSIQNQVIEFGWETILAWEVDDEG---MAFCLQYHRPD--KSPRWVRIFTPYFVYMCDCFDRVQEERNRSGKKTYFN 518          
BLAST of Sorting nexin-27 vs. TrEMBL
Match: A0A182NR24 (Uncharacterized protein OS=Anopheles dirus OX=7168 PE=4 SV=1)

HSP 1 Score: 370.933 bits (951), Expect = 2.253e-118
Identity = 219/492 (44.51%), Postives = 295/492 (59.96%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINEP-ESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEK--NLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEESS 1516
            PRVV I K+++GFGFNVRGQV EGGQL+SINGELYAPLQ VSAVL NGAAE+AG+ K DRILEVN VNVEGATHKQVVDLIKSGG+TL LTVIS    + E ++P+ D   +S  D+ E+R+LPISIP Y++I+   E YVV+NIH++ + +CSRRYRE  + H QLK  F  FN P  P KWPF LNEQQL+ARRR LEQYL  VC+ R IAESD VQ  L D++      +A  +D+KI LP++ +  + + ++ N   +  +     +       YF  F I   NF  KL     P+    ++++   ST L +RRW F+   E+ L         +FY  A +E+     R D +   L +L   ++ D+   YL L R+L  Y +IVFP C+  ++K G V+P    KS +L A  ++G  E   +   W+ IS+    ++D   +AF       D     R VK+ +  + FL +C  R  EE S
Sbjct:   45 PRVVTIYKTETGFGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLDNGAAEQAGIKKGDRILEVNHVNVEGATHKQVVDLIKSGGDTLTLTVISVTQQEAERLEPTEDPGGYSYIDYSEKRSLPISIPDYNIIHRGNERYVVFNIHMAGRQLCSRRYREFSNLHQQLKKEFSGFNFPKMPGKWPFQLNEQQLDARRRGLEQYLEKVCAVRVIAESDAVQEFLTDTVDDL---AASPVDIKIMLPDHAVVTVSVRKSANAQLVWEQLVQRANLTSYTQQYFYLFEIVEYNFERKLQPHEIPHQLYVQNYSTASSTCLCVRRWLFSVEREMSLPAGEQAAKFIFY-QAVDEVNRSNIRADGRLYELKALQDSKKADE---YLSLARTLPGYGDIVFPHCSCDSRKEGHVVPAVGMKSFRLHACREDGALEAQTVELQWATISRW---ESDEESMAFCFQYSRSD--KPPRWVKVFTPYHAFLADCFDRIMEERS 524          
BLAST of Sorting nexin-27 vs. Ensembl Cavefish
Match: snx27b (sorting nexin 27 [Source:NCBI gene;Acc:103032389])

HSP 1 Score: 330.102 bits (845), Expect = 1.897e-105
Identity = 193/487 (39.63%), Postives = 288/487 (59.14%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKN--LLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PR+V I KS SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G   L+L V+S    + +++DP  D S  S  D+ +++ +PIS+PTY  + +  E +VVYN++++ + +CS+RYRE    H  LK  F  F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+I++P+     +++ +N     +     + +  +     YF  F +   +F  KL     P+    +++   V  T L LR+W F    E+ L      +   F+  A ++++    + +EK+  L  LS+ R+I     YL + RS + Y EI+FP C   +++ G V+   +    +L A  +EG  E+ +++F W+++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   54 PRLVRIVKSDSGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGISKGDRILEVNGVNVEGATHKQVVDLIRAGERELVLAVLSVPQPETDSLDPGDDGSAQSCYDYSDKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFATFTFPKLPGKWPFSLSEQQLDARRRGLEEYLERVCSVRVIGESDIMQEFLSESDEN--YNGVSDVELRIAMPDKTTVTVRVRKNCTTDQVYQAVVMKVGMDSITASYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTLRKWLFTTEEEILLNDNELAINYCFH-QALDDVKRGFIKAEEKSYQLQKLSEQRKIS---MYLSMVRSCEGYNEIIFPHCACDSRRKGHVVTAISIHHFKLHACTEEGTLENQVIAFEWAEMQRW---DTDEEGMAFCFEYTR--GEKKPRWVKIFTPYFNYMHECFER 529          
BLAST of Sorting nexin-27 vs. Ensembl Cavefish
Match: snx27a (sorting nexin-27 [Source:NCBI gene;Acc:103026625])

HSP 1 Score: 325.865 bits (834), Expect = 4.747e-104
Identity = 188/485 (38.76%), Postives = 287/485 (59.18%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PR+V I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGV+VEGATHKQVVDLI++G + L+L V+S    + + +DP  D S     D+ +++ +PIS+PTY  + +  E +VVYNI++S + +CS+RYRE    +  LK  F  +  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+I+LP+     +++ +N     +     + +  +  +  YF  F +   +F  KL     P+    +++   V  T L LR+W F+   E +L++         +  AQ++++    ++++K+   L K  E      YL L R+ + Y E+ FP C+  +++ G VI        +L A  ++G  E+ +++F W+++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   37 PRIVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGISKGDRILEVNGVSVEGATHKQVVDLIRAGEKELVLAVLSVPPQEVDGLDPGEDGSATPNYDYSDKQAVPISVPTYKHVEQHGERFVVYNIYMSGRQLCSKRYREFAILNQNLKREFGTYTFPKLPGKWPFSLSEQQLDARRRGLEEYLERVCSVRVIGESDIMQEFLSESDEN--YNGVTDVELRIALPDKTTISVRVRKNSTTDQVYQALVMKVGMDSIMASYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLALRKWLFSTQ-EHDLLRDNPLALHYCFHQAQDDVKKGFIKVEDKS-YQLQKLAEQRKMATYLSLLRTCEGYNEVTFPHCSCDSRRKGHVISAIGIHHFKLHACTEDGTLENQVIAFEWAEMLRW---DTDEEGMAFCFEYTR--GEKKPRWVKIFTPYFNYMHECFER 512          
BLAST of Sorting nexin-27 vs. Ensembl Cavefish
Match: snx27b (sorting nexin 27 [Source:NCBI gene;Acc:103032389])

HSP 1 Score: 320.857 bits (821), Expect = 6.814e-103
Identity = 191/485 (39.38%), Postives = 275/485 (56.70%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PR+V I KS SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G   L+L V+S    + +++DP  D S  S  D+ +++ +PIS+PTY  + +  E +VVYN++++ + +CS+RYRE    H  LK  F  F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+I++P+     +++ +N     +     + +  +     YF  F +   +F  KL     P+    +++   V  T L LR+W F    E+ L     N  E    LA N   HQ                       YL + RS + Y EI+FP C   +++ G V+   +    +L A  +EG  E+ +++F W+++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   24 PRLVRIVKSDSGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGISKGDRILEVNGVNVEGATHKQVVDLIRAGERELVLAVLSVPQPETDSLDPGDDGSAQSCYDYSDKQAVPISVPTYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFATFTFPKLPGKWPFSLSEQQLDARRRGLEEYLERVCSVRVIGESDIMQEFLSESDEN--YNGVSDVELRIAMPDKTTVTVRVRKNCTTDQVYQAVVMKVGMDSITASYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLTLRKWLFTTEEEILL-----NDNE----LAINYCFHQ-----------------------YLSMVRSCEGYNEIIFPHCACDSRRKGHVVTAISIHHFKLHACTEEGTLENQVIAFEWAEMQRW---DTDEEGMAFCFEYTR--GEKKPRWVKIFTPYFNYMHECFER 469          
BLAST of Sorting nexin-27 vs. Ensembl Cavefish
Match: snx27a (sorting nexin-27 [Source:NCBI gene;Acc:103026625])

HSP 1 Score: 316.62 bits (810), Expect = 7.143e-101
Identity = 187/479 (39.04%), Postives = 285/479 (59.50%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRGNFYEKLPNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PR+V I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGV+VEGATHKQVVDLI++G + L+L V+S    + + +DP  D S     D+ +++ +PIS+PTY  + +  E +VVYNI++S + +CS+RYRE    +  LK  F  +  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+I+LP+     +++ +N     +   + ++      IL  F F +   N   + P+    +++   V  T L LR+W F+   E +L++         +  AQ++++    ++++K+   L K  E      YL L R+ + Y E+ FP C+  +++ G VI        +L A  ++G  E+ +++F W+++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   37 PRIVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGISKGDRILEVNGVSVEGATHKQVVDLIRAGEKELVLAVLSVPPQEVDGLDPGEDGSATPNYDYSDKQAVPISVPTYKHVEQHGERFVVYNIYMSGRQLCSKRYREFAILNQNLKREFGTYTFPKLPGKWPFSLSEQQLDARRRGLEEYLERVCSVRVIGESDIMQEFLSESDEN--YNGVTDVELRIALPDKTTISVRVRKNSTTDQV---YQVHFY----ILHIFMFILLAPN---EFPHKLYVQNYTSAVPGTCLALRKWLFSTQ-EHDLLRDNPLALHYCFHQAQDDVKKGFIKVEDKS-YQLQKLAEQRKMATYLSLLRTCEGYNEVTFPHCSCDSRRKGHVISAIGIHHFKLHACTEDGTLENQVIAFEWAEMLRW---DTDEEGMAFCFEYTR--GEKKPRWVKIFTPYFNYMHECFER 496          
BLAST of Sorting nexin-27 vs. Ensembl Cavefish
Match: snx17 (sorting nexin 17 [Source:NCBI gene;Acc:103029430])

HSP 1 Score: 77.7962 bits (190), Expect = 7.673e-15
Identity = 60/260 (23.08%), Postives = 118/260 (45.38%), Query Frame = 2
Query:  479 SYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFG-FFIPRG-----NFYEKLPNDALSESFACGVST---SLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPAC 1231
            +YV YNIH++  L C  RY +L   H Q+K  + +   P+FP K  F+L   ++E RR  LE+Y+  V     +  S++  + L  + + T     +++ L+I L N +   + I  +    ++L   A  +   ++++ YF  F I  G      F  KL    L       +      + LR+ +++ A + ++++    L  + Y    ++IE     +++     L   +E   +  +++L ++L  +  I F  C
Sbjct:   18 TYVAYNIHVNGVLHCRVRYSQLLGLHEQIKKEYGNNVVPTFPPKKIFTLTPAEVEQRREQLEKYMQAVRQDPLLGASEMFNSFLRKAQQETQQIPTEDVQLEIHLSNGQKVKVNILTSDQTEDVLEAVATKLDLPDDLVGYFSLFLIQEGVEGSCTFVRKLQEFELPYVSVTSLRNPDYHIVLRKSYWDSAYDRDVMENRVGLN-LLYAQTVSDIERGWILVNKDQHRQLKSLQEKGSKKEFIRLAQTLKYFGYIKFDPC 276          
BLAST of Sorting nexin-27 vs. Ensembl Sea Lamprey
Match: snx17 (sorting nexin 17 [Source:NCBI gene;Acc:568263])

HSP 1 Score: 86.2705 bits (212), Expect = 1.834e-18
Identity = 71/309 (22.98%), Postives = 135/309 (43.69%), Query Frame = 2
Query:  434 LPISIP-TYSMINEPESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRG------NFYEKLPNDAL---SESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSG-KVIPRCNFKSLQLQAANDEGEAED 1327
            +  SIP T     E   +V YNIH++  L C  RY ++   H QLK          FP K    L+  Q+E RR  LE+Y+  V     +  S++  + L  + + T    +  + L++ L N ++  + +   +   +IL   A  +   EE++ YF  F+ R       +F  +L    L   S +    +   + LR+ +++ A + ++++    L  + Y+ A +++E       ++ L  L   ++   +  Y+Q  ++L  Y  + F  C +   + G KVI     K L  +      +A++
Sbjct:    1 MHFSIPDTEEWAGEAARFVTYNIHVNGALHCRVRYSQMHGLHEQLKRCSGGGVGQMFPPKRLLPLSSAQVEQRRELLERYIQAVSQDPVLGTSEVFHSFLRKAQQDTQQVPSQAVQLQVLLANGQMVSVHVESTHQTDDILEAVAAKLELPEELVHYFALFLVRDRGGGAFSFIRRLQEFELPYISVTSLQSLDYKIVLRKSYWDTAYDDDIMESIVGLN-LLYIQAVSDVERGWIVASKEQLQQLKSLQDKGSKKEYIQFSQTLKYYGYLQFDPCITDFPEKGCKVIVAVGNKELNFRVLLSSDQAKE 308          
BLAST of Sorting nexin-27 vs. Ensembl Sea Lamprey
Match: lin7a (lin-7 homolog A (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-1665])

HSP 1 Score: 62.7734 bits (151), Expect = 1.186e-11
Identity = 37/98 (37.76%), Postives = 56/98 (57.14%), Query Frame = 2
Query:   62 DYYKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKY-DRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 352
            + +  PRVV +PK+  G GFN+ G        K  N  +Y     +S ++P G A++ G LK  D++L VNGV+VEG  H++ V+L+K    T+ L V
Sbjct:   73 EGHAHPRVVELPKTDEGLGFNIMGG-------KEQNSPIY-----ISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHEKAVELLKQAQGTVKLVV 158          
BLAST of Sorting nexin-27 vs. Ensembl Sea Lamprey
Match: LIN7B (lin-7 homolog B, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17788])

HSP 1 Score: 57.3806 bits (137), Expect = 5.757e-10
Identity = 37/98 (37.76%), Postives = 55/98 (56.12%), Query Frame = 2
Query:   62 DYYKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKY-DRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 352
            D +  PRV + PK+  G GFNV G        K  N  +Y     +S ++P G A++ G LK  D++L VNGV+VEG  H++ V+L+K    ++ L V
Sbjct:   64 DGHAHPRVEL-PKTDEGLGFNVMGG-------KEQNSPIY-----ISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHERAVELLKQAQGSVKLVV 148          
BLAST of Sorting nexin-27 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005276.1 (pep scaffold:Pmarinus_7.0:GL477718:53:8870:1 gene:ENSPMAG00000004775.1 transcript:ENSPMAT00000005276.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 1.777e-8
Identity = 52/258 (20.16%), Postives = 105/258 (40.70%), Query Frame = 2
Query:  593 PSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRGNFYEKLPNDALSESFACGV---------STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPAC--------NSTAKKSGKVIPRCNFKSLQLQAANDEG 1315
            P FP K  F+L++ Q E RRR +EQYL  +     +++S+LV + L  + + T       +++ + LP+ E   + I       ++L    + +   +++L  FG F+       +L      + F              + LFLR  + +  ++  ++     L ++ Y  A  +I+     +D      L++  +      +L++ +SL  Y  +    C        +  A ++G  +  C       Q   +EG
Sbjct:   31 PPFPPKRLFALSDAQTEERRRQIEQYLQCISQDEEMSKSELVTSFLRKAQQDTWEVHEAQVEVHVVLPSGETSPVVIPNTSPTHSVLQAVGVAVGIPDDLLPNFGLFLGHAEGERQLTLVRRLQEFELPFVSVISSPIKGSCLFLRTSYLDRELDKFVMADAVGL-KLLYQQAVADIKRGWCEVDAAQKQKLAELHKHGTFEEFLRVAQSLPQYGCVRLDKCECDWPEPDSRAAVRAGGGVLACRSTRPGGQGTTEEG 287          
BLAST of Sorting nexin-27 vs. Ensembl Sea Lamprey
Match: ARHGEF11 (Rho guanine nucleotide exchange factor 11 [Source:HGNC Symbol;Acc:HGNC:14580])

HSP 1 Score: 48.1358 bits (113), Expect = 6.356e-6
Identity = 31/83 (37.35%), Postives = 45/83 (54.22%), Query Frame = 2
Query:   80 RVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSG 328
            R VI+ K + GFG  V G           +  ++     V +V  +GAA +AG+ + DRI++VNG  V  + H +VV LIKSG
Sbjct:    6 RCVIVQKDEFGFGLTVSG-----------DNPVF-----VQSVRKDGAAMRAGVQQGDRIIKVNGTLVTQSNHLEVVKLIKSG 72          
BLAST of Sorting nexin-27 vs. Ensembl Nematostella
Match: EDO47744 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLS4])

HSP 1 Score: 244.973 bits (624), Expect = 4.694e-75
Identity = 161/435 (37.01%), Postives = 228/435 (52.41%), Query Frame = 2
Query:   80 RVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILT---VISSQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINEPESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRGNFYEKLPNDALSESFACGVSTSLFLRR-WFFNP---AIEVELIKKYSNLTEMFYV------LAQNEIEHQK-HRIDEKNLLSLSKYREIDDEYN------YLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAE 1324
            R++ + K  +GFGFNVRGQV EGGQL+SINGELYAPLQ VSAVL NG A + G++  DRILEVN  NV G+  KQ  + + +G   +  T     S +H  ++     +     ++L    + ISIP  +         VYNI+ S K +CS+RY+E  + H+QLK  F DF  P FP KWPF+L+E QLEARR+ LE YL  VCS   I +S L+Q+ L D  K    D+   I+L+I LP+N + ++ + + Y    +       I  ++E   YF  F            +  +  FA  +ST    RR W +N    AI   LI + S       V      +A N + HQ    I  + L   +K +++ D  N      YL + R+LD Y  +VFP C   A+++G VI     KS Q++A  ++G  E
Sbjct:    2 RLIELKKGPNGFGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLENGPAHRGGVIVGDRILEVNPGNVPGSAKKQFKNYLIAGFVFIKCTERHQASRKHIQLNQQQHKAKKQFKNYLIAGFVFISIPFVT---------VYNIYYSGKQICSKRYKEFSNLHSQLKKEFRDFQFPKFPGKWPFTLSEHQLEARRKGLESYLQQVCSVFVIGDSVLMQDFLDDDDKME--DTEMEIELRILLPDNSVEIVVVEKRYKTREVYKALVSKIGLDQESALYFALF------------EVTASGFATALSTDFITRRAWPYNAGLSAIFSLLILRNSGKRSFDEVELNSDEVALNLLYHQALEDIKSRKLTPGTKLQQLKDLKNSSKKREYLDVARTLDHYNTVVFPHCPCDARRNGHVITTICLKSFQMKACTEDGVLE 413          
BLAST of Sorting nexin-27 vs. Ensembl Nematostella
Match: EDO37172 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGL2])

HSP 1 Score: 78.5666 bits (192), Expect = 1.459e-15
Identity = 74/307 (24.10%), Postives = 135/307 (43.97%), Query Frame = 2
Query:  479 SYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFG-FFIPRGNFYEKLPNDALSESFACGV--------STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPAC-NSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIR 1369
            +++ YNIH++  L  + R+ +L  F+ QLK  + +     FP +   SL   Q+E RR  LE+YL  +C    +A S    + L +  K T    ++ + L + L N     LK+    +  ++L      I  +EE+  YF  F I R    E      L E F C          +  + +R+ F++  +E  +I+    +  + YV A ++IE       ++    L + +E   +  YL+L R +  Y  I F  C  +    + +V+  C  + L  +      + ED+ +  G   ++++R
Sbjct:   18 TFLAYNIHINGALHSAVRFSDLYQFNEQLKKEYGNRITARFPPRKILSLTAVQVEERRDQLEKYLQGICQDPDVANSSTFTDFLRNCQKETLQALSETVTLDVYLMNGSKVSLKVLSTDSTDDVLEAAMREIKLSEELFHYFALFLIKREEDGEATIQRKLQE-FECPYLSVKNLKGTHRIAVRKNFWDSKLEDRIIEDKIGMN-LLYVQAISDIERGWVVGPKEAYSRLEELKETGSKKEYLRLARMMKYYGFIQFKPCFTNYPTDNTRVLISCGDRELNFRL-----QTEDNKIQEGSFKVTRMR 317          
BLAST of Sorting nexin-27 vs. Ensembl Nematostella
Match: EDO47722 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLN6])

HSP 1 Score: 63.1586 bits (152), Expect = 1.808e-11
Identity = 37/98 (37.76%), Postives = 56/98 (57.14%), Query Frame = 2
Query:   62 DYYKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKY-DRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 352
            + +  PRVV +PK+  G GFNV G        +  N  +Y     +S ++P G A++ G LK  D++L VNGV+VEG  H++ VDL+K    ++ L V
Sbjct:   85 EGHAHPRVVELPKTDEGLGFNVMGG-------REQNSPIY-----ISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGENHEKAVDLLKEAQGSVRLVV 170          
BLAST of Sorting nexin-27 vs. Ensembl Nematostella
Match: EDO42418 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1S4])

HSP 1 Score: 53.1434 bits (126), Expect = 4.818e-9
Identity = 33/87 (37.93%), Postives = 43/87 (49.43%), Query Frame = 2
Query:   92 IPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 352
            + K   G+GFN             ++G+   P Q +SAV  +  AE  GL + DR++EVNGVNVE  TH  VV  IK       L V
Sbjct:    1 LKKGSQGYGFN-------------LHGDKTHPGQTISAVDKDSPAEIGGLREGDRVIEVNGVNVEDMTHGDVVKRIKENPNEATLLV 74          
BLAST of Sorting nexin-27 vs. Ensembl Nematostella
Match: EDO33432 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SS78])

HSP 1 Score: 55.0694 bits (131), Expect = 6.556e-8
Identity = 41/134 (30.60%), Postives = 64/134 (47.76%), Query Frame = 2
Query:   92 IPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKY-DRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINEPESYVV 490
            I +   G G N+ G  G+G      N E       +S +  NG A + G+L   D+IL+VNGV++  ATH Q VD++KS G+ + L V+  + E                +E+R +P +    S+  EP+   V
Sbjct:  571 IHRDTKGLGINIAG--GKGSTPYKENDEGIF----ISRISENGPAGRDGILHVGDKILKVNGVDISNATHHQAVDVLKSTGKDITLYVVREKQE----------------IEKRTVPKTAKDESVKEEPKKTGV 682          
BLAST of Sorting nexin-27 vs. Ensembl Medaka
Match: ENSORLT00000000704.2 (sorting nexin-27 [Source:NCBI gene;Acc:101156506])

HSP 1 Score: 332.028 bits (850), Expect = 2.171e-106
Identity = 192/484 (39.67%), Postives = 279/484 (57.64%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS-SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINE-PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRID-EKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PR+V I KS+SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG++K DRILEVNGV+VEGATHKQVVDLI++G + L+L V+S    E              D+ +++ +PISIPTY  + +  E +VVYN+++S + +CS+RYRE    H  LK  F +FN P FP KWPF+L+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+I LP+     +++ +N     +     + +  +  +  YF  F +   +F  KL     P+    +++   V  T L LR+W F+   E E ++   N   + Y   Q   + +K  I  E     L K  E      YL L R+ + Y E+VFP C   +++ G VI        +L A  ++G  E+ +++F W+++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   42 PRMVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGIVKGDRILEVNGVSVEGATHKQVVDLIRAGEKELVLAVLSVPPQEAEGLEGGEDIQPNYDYSDKQAVPISIPTYKHVEQHSERFVVYNVYMSGRQLCSKRYREFAILHQNLKREFSNFNFPKFPGKWPFTLSEQQLDARRRGLEEYLERVCSVRVIGESDVMQEFLSESDEN--YNGVTDVELRILLPDKTTISVRVRKNSTTDQVYQALTLKVGMDSVMASYFALFEVINHSFVRKLAPNEFPHKLYVQNYTSAVPGTCLALRKWLFS-VQEEEFLR--DNPLALHYCFHQALDDVKKGFIKTEDKSYQLQKLAEQHKMATYLSLLRTCEGYNEVVFPHCACDSRRKGHVITAIGIHHFKLHACTEDGALENQVIAFEWAEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 515          
BLAST of Sorting nexin-27 vs. Ensembl Medaka
Match: SNX27 (sorting nexin-27-like [Source:NCBI gene;Acc:101155380])

HSP 1 Score: 327.405 bits (838), Expect = 3.633e-104
Identity = 193/486 (39.71%), Postives = 281/486 (57.82%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMIN-EPESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRID-EKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLR 1498
            PR V I KS SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G   L+LTV+S    + + +D   D S  S  D+ +++ +PISIP+Y   +   E +VVY+++++ + +CS+RYRE    H  LK  F  F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+I++P+     +++ +N     +     + +  +     YF  F +    F  KL     P+    +++   +  T L LR+W F    EV L +   NL  + Y   Q   + +K  +  E+    L K  E      YL L RS + Y EI+FP C+  +++ G VI   + +  +L A  ++G  E+ +++F W+++ +    DTD   +AF        G+ K R VKI +    ++ EC  R
Sbjct:   50 PRPVRIVKSDSGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGISKGDRILEVNGVNVEGATHKQVVDLIRAGERELVLTVLSVPPQEADCLDLGDDGSAQSCYDYSDKQAVPISIPSYKHTDLNSEKFVVYHVYMAGRQLCSKRYREFVILHQNLKREFGSFAFPKLPGKWPFSLSEQQLDARRRGLEEYLEKVCSVRVIGESDIMQEFLSESDEN--YNGVSDVELRIAMPDKTTLTVRVRKNSTTDQVYQAVVMKLGMDSVTASYFALFEVINHTFVRKLAPNEFPHKLYVQNYTSAIPGTCLTLRKWLFTTKEEVLLNE---NLLAVSYFFHQAVDDLKKGFVKAEQKSYQLQKLAEQKKMATYLSLLRSCEGYNEIIFPHCSCDSRRKGHVITAISIQHFKLHACTEDGTLENQVIAFDWAEMQRW---DTDEEGMAFCFEYAR--GEKKPRWVKIFTPYFNYMHECFER 525          
BLAST of Sorting nexin-27 vs. Ensembl Medaka
Match: SNX27 (sorting nexin-27-like [Source:NCBI gene;Acc:101155380])

HSP 1 Score: 306.99 bits (785), Expect = 2.386e-97
Identity = 177/428 (41.36%), Postives = 252/428 (58.88%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS---SQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMIN-EPESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFF-IPRGNFYEKL-----PNDALSESFACGV-STSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRID-EKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAE 1324
            PR V I KS SG+GFNVRGQV EGGQL+SINGELYAPLQ VSAVLP GAA++AG+ K DRILEVNGVNVEGATHKQVVDLI++G   L+LTV+S    + + +D   D S  S  D+ +++ +PISIP+Y   +   E +VVY+++++ + +CS+RYRE    H  LK  F  F  P  P KWPFSL+EQQL+ARRR LE+YL  VCS R I ESD++Q  L +S +    +   +++L+I++P+     +++ +N     +     + +  +     YF  F +    F  KL     P+    +++   +  T L LR+W F    EV L +   NL  + Y   Q   + +K  +  E+    L K  E      YL L RS + Y EI+FP C+  +++ G VI   + +  +L A  ++G  E
Sbjct:   49 PRPVRIVKSDSGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAGISKGDRILEVNGVNVEGATHKQVVDLIRAGERELVLTVLSVPPQEADCLDLGDDGSAQSCYDYSDKQAVPISIPSYKHTDLNSEKFVVYHVYMAGRQLCSKRYREFVILHQNLKREFGSFAFPKLPGKWPFSLSEQQLDARRRGLEEYLEKVCSVRVIGESDIMQEFLSESDEN--YNGVSDVELRIAMPDKTTLTVRVRKNSTTDQVYQAVVMKLGMDSVTASYFALFEVINHTFVRKLAPNEFPHKLYVQNYTSAIPGTCLTLRKWLFTTKEEVLLNE---NLLAVSYFFHQAVDDLKKGFVKAEQKSYQLQKLAEQKKMATYLSLLRSCEGYNEIIFPHCSCDSRRKGHVITAISIQHFKLHACTEDGTLE 471          
BLAST of Sorting nexin-27 vs. Ensembl Medaka
Match: snx17 (sorting nexin 17 [Source:NCBI gene;Acc:101168261])

HSP 1 Score: 77.411 bits (189), Expect = 1.024e-14
Identity = 61/260 (23.46%), Postives = 112/260 (43.08%), Query Frame = 2
Query:  479 SYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRG------NFYEKLPNDALSESFACGVSTSLF---LRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPAC 1231
            +YV YNIH++  L C  RY +L   H Q+K  +     P+FP K  F+L   ++E RR  LE+Y+  V  +  +  SDL  + L  + + T     +   L I L +     + I  +    ++L      +   ++++ YF  F+          F  KL    L       + +S F   LR+ +++ A + +++     L  + Y    ++IE     +++     L   +E   +  ++ L ++L  Y  I F  C
Sbjct:   18 TYVAYNIHVNGVLHCRVRYSQLLGLHEQIKKEYGSNVVPNFPPKKIFTLTPAEVEQRREQLEKYMQAVRQHPLLGASDLFNSFLRKAQQETQQIPTEEAALDICLCSGPKLTVHILTSDQTEDVLEAVGTKLDLPDDLVGYFSLFLVHEGVDGSLTFVRKLQEFELPYVSITSLQSSEFHIVLRKSYWDMAYDQDVMDNRVGLN-LLYAQTVSDIERGWILVNKDQQRQLKSLQEKGSKKEFIHLAQTLKYYGYIKFDPC 276          
BLAST of Sorting nexin-27 vs. Ensembl Medaka
Match: snx17 (sorting nexin 17 [Source:NCBI gene;Acc:101168261])

HSP 1 Score: 77.411 bits (189), Expect = 1.152e-14
Identity = 61/260 (23.46%), Postives = 112/260 (43.08%), Query Frame = 2
Query:  479 SYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRG------NFYEKLPNDALSESFACGVSTSLF---LRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPAC 1231
            +YV YNIH++  L C  RY +L   H Q+K  +     P+FP K  F+L   ++E RR  LE+Y+  V  +  +  SDL  + L  + + T     +   L I L +     + I  +    ++L      +   ++++ YF  F+          F  KL    L       + +S F   LR+ +++ A + +++     L  + Y    ++IE     +++     L   +E   +  ++ L ++L  Y  I F  C
Sbjct:   18 TYVAYNIHVNGVLHCRVRYSQLLGLHEQIKKEYGSNVVPNFPPKKIFTLTPAEVEQRREQLEKYMQAVRQHPLLGASDLFNSFLRKAQQETQQIPTEEAALDICLCSGPKLTVHILTSDQTEDVLEAVGTKLDLPDDLVGYFSLFLVHEGVDGSLTFVRKLQEFELPYVSITSLQSSEFHIVLRKSYWDMAYDQDVMDNRVGLN-LLYAQTVSDIERGWILVNKDQQRQLKSLQEKGSKKEFIHLAQTLKYYGYIKFDPC 276          
BLAST of Sorting nexin-27 vs. Planmine SMEST
Match: SMESG000081127.1 (SMESG000081127.1)

HSP 1 Score: 1014.22 bits (2621), Expect = 0.000e+0
Identity = 508/508 (100.00%), Postives = 508/508 (100.00%), Query Frame = 2
Query:   23 MSLDNLNNINATLDYYKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQHENIXXXXXXXXXXXXXFLERRNLPISIPTYSMINEPESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRGNFYEKLPNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEESSRPMPKICYNY 1546
            MSLDNLNNINATLDYYKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQHENIDPSSDSSDHSPSDFLERRNLPISIPTYSMINEPESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRGNFYEKLPNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEESSRPMPKICYNY
Sbjct:    1 MSLDNLNNINATLDYYKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVISSQHENIDPSSDSSDHSPSDFLERRNLPISIPTYSMINEPESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRGNFYEKLPNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRIDDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEESSRPMPKICYNY 508          
BLAST of Sorting nexin-27 vs. Planmine SMEST
Match: SMESG000057909.1 (SMESG000057909.1)

HSP 1 Score: 63.929 bits (154), Expect = 1.781e-11
Identity = 37/96 (38.54%), Postives = 56/96 (58.33%), Query Frame = 2
Query:   68 YKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEK-AGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 352
            +  PRVV IPK++ G GFNV G        K  N  +Y     +S ++P G A++  GL + D++L VNG++VE   H++ VDL+K+   T+ L V
Sbjct:   85 HAHPRVVEIPKTEEGLGFNVMGG-------KEQNSPIY-----ISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVV 168          
BLAST of Sorting nexin-27 vs. Planmine SMEST
Match: SMESG000014775.1 (SMESG000014775.1)

HSP 1 Score: 61.2326 bits (147), Expect = 1.595e-9
Identity = 38/100 (38.00%), Postives = 56/100 (56.00%), Query Frame = 2
Query:   77 PRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAP------LQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTVIS 358
            PRVV++ K+  GFGF +RG       LK+ +   + P      LQ    V  N  A +AGL K D ILE+N ++V  A+H+  V LIK+ G+ L + V++
Sbjct:  556 PRVVVLQKNSQGFGFVIRG-------LKASSTINFRPTLKNPALQYFEEVEVNSVAARAGLKKGDFILEINNLSVVSASHEDTVRLIKASGDILAMKVVT 648          
BLAST of Sorting nexin-27 vs. Planmine SMEST
Match: SMESG000010501.1 (SMESG000010501.1)

HSP 1 Score: 60.8474 bits (146), Expect = 1.670e-9
Identity = 75/327 (22.94%), Postives = 132/327 (40.37%), Query Frame = 2
Query:  488 VYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRGNFYEKLP---------------NDALSESFACGVSTS-----LFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEI---------EHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPA---CNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRI 1372
            ++ I+++    CS R+  L   +  LKL F     P FP K    LN+ QLE RR +LE +L  V S  T   S      L    K T     +++ + + L + + + + I    N   +   FA  IS   +I   FG +    +  +K                 N+ L+E      ++S     + +R+  +N  +E ++   Y  L E+ +     EI         E +++RI  +NL+     +E       LQL R+LD Y  +       CN  A+ S  ++   NF+ +    ++  G     + ++  + I   +I
Sbjct:   21 IFKIYINGAHHCSARFSVLHKLNEDLKLRFQVTELPYFPPKKFLKLNDAQLEERRESLEYFLQKVSS-STRFNSHEFHEFLKTCQKETKKIVNESVSISVYLMDGQEYQMDIQNTDNTQAVFDAFADAISLPRQISSKFGLYFMEMHPADKFSIIRKIQDFEYPYISLNEILTERRNRNRNSSDNNCRIVVRKSQWNSELETDIDSSYPAL-EILFAQVAAEIHNGWISIPDESRRNRI--QNLIQRKARKEA------LQLARTLDFYGYVQLHGRSICNRPAQNSHVIVSAGNFQLVLRDGSDGNGNRGAVLFTYCLTRIKAWKI 337          
BLAST of Sorting nexin-27 vs. Planmine SMEST
Match: SMESG000010501.1 (SMESG000010501.1)

HSP 1 Score: 60.8474 bits (146), Expect = 1.674e-9
Identity = 75/327 (22.94%), Postives = 132/327 (40.37%), Query Frame = 2
Query:  488 VYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFSLNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADNIDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPRGNFYEKLP---------------NDALSESFACGVSTS-----LFLRRWFFNPAIEVELIKKYSNLTEMFYVLAQNEI---------EHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVFPA---CNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRI 1372
            ++ I+++    CS R+  L   +  LKL F     P FP K    LN+ QLE RR +LE +L  V S  T   S      L    K T     +++ + + L + + + + I    N   +   FA  IS   +I   FG +    +  +K                 N+ L+E      ++S     + +R+  +N  +E ++   Y  L E+ +     EI         E +++RI  +NL+     +E       LQL R+LD Y  +       CN  A+ S  ++   NF+ +    ++  G     + ++  + I   +I
Sbjct:   21 IFKIYINGAHHCSARFSVLHKLNEDLKLRFQVTELPYFPPKKFLKLNDAQLEERRESLEYFLQKVSS-STRFNSHEFHEFLKTCQKETKKIVNESVSISVYLMDGQEYQMDIQNTDNTQAVFDAFADAISLPRQISSKFGLYFMEMHPADKFSIIRKIQDFEYPYISLNEILTERRNRNRNSSDNNCRIVVRKSQWNSELETDIDSSYPAL-EILFAQVAAEIHNGWISIPDESRRNRI--QNLIQRKARKEA------LQLARTLDFYGYVQLHGRSICNRPAQNSHVIVSAGNFQLVLRDGSDGNGNRGAVLFTYCLTRIKAWKI 337          
The following BLAST results are available for this feature:
BLAST of Sorting nexin-27 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SNX273.512e-10840.21sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:2007... [more]
SNX273.599e-10840.21sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:2007... [more]
SNX275.866e-5530.99sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:2007... [more]
SNX273.903e-5030.52sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:2007... [more]
SNX277.821e-2679.69sorting nexin 27 [Source:HGNC Symbol;Acc:HGNC:2007... [more]
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BLAST of Sorting nexin-27 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snx-271.373e-7835.35Sorting NeXin [Source:UniProtKB/TrEMBL;Acc:Q93566... [more]
lin-74.439e-1137.50pep chromosome:WBcel235:II:14346877:14348792:-1 ge... [more]
lin-75.241e-936.46pep chromosome:WBcel235:II:14347162:14348792:-1 ge... [more]
shn-12.805e-834.41pep chromosome:WBcel235:II:11384594:11390862:-1 ge... [more]
shn-13.062e-834.41pep chromosome:WBcel235:II:11384594:11390862:-1 ge... [more]
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BLAST of Sorting nexin-27 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Snx274.468e-11842.83gene:FBgn0052758 transcript:FBtr0070843[more]
Snx273.239e-8036.18gene:FBgn0052758 transcript:FBtr0339525[more]
Snx276.899e-7937.03gene:FBgn0052758 transcript:FBtr0340670[more]
Prosap3.263e-1338.38gene:FBgn0040752 transcript:FBtr0339763[more]
Prosap3.286e-1338.38gene:FBgn0040752 transcript:FBtr0087601[more]
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BLAST of Sorting nexin-27 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snx27a2.092e-10839.71sorting nexin 27a [Source:ZFIN;Acc:ZDB-GENE-060503... [more]
snx27b2.682e-10539.59sorting nexin 27b [Source:ZFIN;Acc:ZDB-GENE-040426... [more]
snx176.155e-1522.69sorting nexin 17 [Source:NCBI gene;Acc:568263][more]
snx177.584e-1522.69sorting nexin 17 [Source:NCBI gene;Acc:568263][more]
slc9a3r1b7.516e-1237.84SLC9A3 regulator 1b [Source:ZFIN;Acc:ZDB-GENE-1705... [more]
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BLAST of Sorting nexin-27 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SNX275.001e-9147.89sorting nexin family member 27 [Source:NCBI gene;A... [more]
chrnb37.385e-1241.00cholinergic receptor, nicotinic beta 3 [Source:Xen... [more]
lin7a2.262e-1139.58lin-7 homolog A [Source:NCBI gene;Acc:100144984][more]
lin7a2.264e-1139.58lin-7 homolog A [Source:NCBI gene;Acc:100144984][more]
ENSXETT00000028683.15.577e-1138.54lin-7 homolog B [Source:NCBI gene;Acc:100491827][more]
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BLAST of Sorting nexin-27 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Snx273.008e-11140.82sorting nexin family member 27 [Source:MGI Symbol;... [more]
Snx273.835e-11140.82sorting nexin family member 27 [Source:MGI Symbol;... [more]
Snx271.333e-7234.92sorting nexin family member 27 [Source:MGI Symbol;... [more]
Snx276.510e-2752.13sorting nexin family member 27 [Source:MGI Symbol;... [more]
Snx171.425e-1623.85sorting nexin 17 [Source:MGI Symbol;Acc:MGI:238780... [more]
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BLAST of Sorting nexin-27 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q3UHD6|SNX27_MOUSE2.683e-11040.82Sorting nexin-27 OS=Mus musculus OX=10090 GN=Snx27... [more]
sp|Q8K4V4|SNX27_RAT4.839e-11040.82Sorting nexin-27 OS=Rattus norvegicus OX=10116 GN=... [more]
sp|A5PKA5|SNX27_BOVIN8.402e-11040.62Sorting nexin-27 OS=Bos taurus OX=9913 GN=SNX27 PE... [more]
sp|Q96L92|SNX27_HUMAN1.728e-10740.21Sorting nexin-27 OS=Homo sapiens OX=9606 GN=SNX27 ... [more]
sp|Q8BVL3|SNX17_MOUSE9.971e-1623.85Sorting nexin-17 OS=Mus musculus OX=10090 GN=Snx17... [more]
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BLAST of Sorting nexin-27 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4Y2J9K87.440e-12345.49Sorting nexin-27 OS=Araneus ventricosus OX=182803 ... [more]
A0A2P6KRG23.835e-12144.88Snx27 OS=Nephila clavipes OX=2585209 GN=NCL1_31074... [more]
A0A087UA664.005e-12043.61Sorting nexin-27 (Fragment) OS=Stegodyphus mimosar... [more]
A0A4Y7NJ631.798e-11842.12EOG090X05ZS OS=Megafenestra aurita OX=2291010 GN=E... [more]
A0A182NR242.253e-11844.51Uncharacterized protein OS=Anopheles dirus OX=7168... [more]
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BLAST of Sorting nexin-27 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snx27b1.897e-10539.63sorting nexin 27 [Source:NCBI gene;Acc:103032389][more]
snx27a4.747e-10438.76sorting nexin-27 [Source:NCBI gene;Acc:103026625][more]
snx27b6.814e-10339.38sorting nexin 27 [Source:NCBI gene;Acc:103032389][more]
snx27a7.143e-10139.04sorting nexin-27 [Source:NCBI gene;Acc:103026625][more]
snx177.673e-1523.08sorting nexin 17 [Source:NCBI gene;Acc:103029430][more]
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BLAST of Sorting nexin-27 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snx171.834e-1822.98sorting nexin 17 [Source:NCBI gene;Acc:568263][more]
lin7a1.186e-1137.76lin-7 homolog A (C. elegans) [Source:ZFIN;Acc:ZDB-... [more]
LIN7B5.757e-1037.76lin-7 homolog B, crumbs cell polarity complex comp... [more]
ENSPMAT00000005276.11.777e-820.16pep scaffold:Pmarinus_7.0:GL477718:53:8870:1 gene:... [more]
ARHGEF116.356e-637.35Rho guanine nucleotide exchange factor 11 [Source:... [more]
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BLAST of Sorting nexin-27 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Sorting nexin-27 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO477444.694e-7537.01Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371721.459e-1524.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO477221.808e-1137.76Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO424184.818e-937.93Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO334326.556e-830.60Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Sorting nexin-27 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000000704.22.171e-10639.67sorting nexin-27 [Source:NCBI gene;Acc:101156506][more]
SNX273.633e-10439.71sorting nexin-27-like [Source:NCBI gene;Acc:101155... [more]
SNX272.386e-9741.36sorting nexin-27-like [Source:NCBI gene;Acc:101155... [more]
snx171.024e-1423.46sorting nexin 17 [Source:NCBI gene;Acc:101168261][more]
snx171.152e-1423.46sorting nexin 17 [Source:NCBI gene;Acc:101168261][more]
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BLAST of Sorting nexin-27 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000081127.10.000e+0100.00SMESG000081127.1[more]
SMESG000057909.11.781e-1138.54SMESG000057909.1[more]
SMESG000014775.11.595e-938.00SMESG000014775.1[more]
SMESG000010501.11.670e-922.94SMESG000010501.1[more]
SMESG000010501.11.674e-922.94SMESG000010501.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30026112 ID=SMED30026112|Name=Sorting nexin-27|organism=Schmidtea mediterranea sexual|type=transcript|length=1771bp
ACTTTTTTGAAAATAACATTCAATGTCATTGGACAATTTAAATAATATAA
ATGCAACTTTAGACTATTATAAAAAACCTAGAGTAGTAATAATTCCTAAA
TCACAAAGTGGTTTTGGATTTAATGTTAGAGGTCAGGTAGGTGAAGGAGG
TCAATTGAAAAGTATTAATGGAGAATTGTATGCTCCTCTACAACAAGTTA
GTGCCGTTTTGCCTAACGGCGCTGCTGAAAAGGCTGGCTTATTAAAGTAT
GACAGGATCCTAGAAGTCAATGGTGTTAACGTGGAAGGTGCAACTCATAA
ACAAGTTGTTGATTTAATTAAATCAGGAGGTGAAACGTTAATATTAACAG
TTATTTCATCTCAACATGAAAATATAGATCCAAGCAGTGATTCTAGTGAT
CATTCACCATCAGATTTTTTGGAAAGACGTAATTTACCTATTTCTATTCC
TACGTATTCTATGATTAACGAACCAGAATCATATGTGGTTTACAACATTC
ATTTATCGAATAAGTTAGTTTGCTCAAGGCGTTATAGAGAACTGGATGAT
TTTCATAATCAATTGAAACTAGCATTCCCAGATTTCAATCGGCCGTCATT
CCCAAGAAAATGGCCATTTTCATTAAACGAACAACAACTTGAAGCCAGAC
GACGAGCACTAGAACAATACCTAGCAATAGTTTGTTCATATCGAACGATT
GCAGAGAGTGATTTGGTTCAGAATCTTTTGTGTGATTCAATAAAAAGGAC
GCCTGTGGATTCTGCAGATAATATTGATTTGAAAATTTCCTTGCCAAACA
ATGAAATATTTCTCCTGAAGATTTCCCGCAATTATAATGTGTCTAATATA
CTCTCAAAATTCGCGATAAATATTTCCTGGAATGAAGAAATATTAGACTA
CTTTGGCTTCTTTATTCCACGTGGAAACTTTTATGAAAAATTACCCAATG
ATGCATTATCCGAATCTTTCGCCTGTGGCGTTTCAACTAGTCTATTTTTA
CGGAGATGGTTTTTTAATCCAGCAATTGAGGTTGAACTTATTAAAAAGTA
TTCCAATCTAACTGAAATGTTTTACGTTCTAGCACAGAATGAAATTGAAC
ATCAAAAACATAGGATAGACGAAAAAAATCTTTTATCTCTATCAAAATAT
CGCGAAATAGACGATGAATATAATTATCTTCAACTTTATAGAAGCCTTGA
CGTTTATGCAGAAATTGTCTTTCCAGCATGTAATAGCACTGCTAAAAAAT
CTGGTAAAGTTATTCCTCGTTGCAATTTCAAATCCCTTCAACTGCAAGCT
GCAAATGATGAAGGAGAAGCAGAGGATCACATCCTATCATTTGGCTGGTC
AGATATTTCCAAAATTCGAATCGACGACACAGACAATCCTTGTGTAGCAT
TTGAATTAACTCTTGTGACTCAAGATGGCAAAGCCAAAACCCGAGACGTT
AAAATTACTAGTATTTCAAATAAGTTCCTAGTTGAATGTATGCTCAGAGC
AAAGGAGGAGTCCAGTAGGCCAATGCCTAAAATATGCTATAACTATTAGA
CCAATGAAAGATTTCCTCTATATATTCACGTGTAAATTTAGAATAGATCT
ATTATGATTATTTATTGATTGCCATTGAATTTATTATATTGATATTGTTG
ATTTTCACTAATAAACATTTCGATATTTCCTGAATTTATTCGATTTTTCA
TTGACTCGCTTTCAAGATTTTCCAAATTAATAAATCAATTATTTTATAAA
ATTTTATTCGAATAAAGTATG
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protein sequence of SMED30026112-orf-1

>SMED30026112-orf-1 ID=SMED30026112-orf-1|Name=SMED30026112-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=509bp
MSLDNLNNINATLDYYKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSING
ELYAPLQQVSAVLPNGAAEKAGLLKYDRILEVNGVNVEGATHKQVVDLIK
SGGETLILTVISSQHENIDPSSDSSDHSPSDFLERRNLPISIPTYSMINE
PESYVVYNIHLSNKLVCSRRYRELDDFHNQLKLAFPDFNRPSFPRKWPFS
LNEQQLEARRRALEQYLAIVCSYRTIAESDLVQNLLCDSIKRTPVDSADN
IDLKISLPNNEIFLLKISRNYNVSNILSKFAINISWNEEILDYFGFFIPR
GNFYEKLPNDALSESFACGVSTSLFLRRWFFNPAIEVELIKKYSNLTEMF
YVLAQNEIEHQKHRIDEKNLLSLSKYREIDDEYNYLQLYRSLDVYAEIVF
PACNSTAKKSGKVIPRCNFKSLQLQAANDEGEAEDHILSFGWSDISKIRI
DDTDNPCVAFELTLVTQDGKAKTRDVKITSISNKFLVECMLRAKEESSRP
MPKICYNY*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006886intracellular protein transport
GO:0007165signal transduction
Vocabulary: molecular function
TermDefinition
GO:0032266phosphatidylinositol-3-phosphate binding
GO:0005515protein binding
GO:0035091phosphatidylinositol binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036034PDZ_sf
IPR036871PX_dom_sf
IPR037831SNX17/27/31
IPR001478PDZ
IPR001683Phox
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001478PDZ domainSMARTSM00228pdz_newcoord: 29..114
e-value: 5.5E-19
score: 79.1
IPR001478PDZ domainPFAMPF00595PDZcoord: 22..110
e-value: 5.8E-14
score: 52.2
IPR001478PDZ domainPROSITEPS50106PDZcoord: 21..114
score: 15.903
IPR001683Phox homologous domainSMARTSM00312PX_2coord: 136..239
e-value: 5.0E-12
score: 56.0
IPR001683Phox homologous domainPFAMPF00787PXcoord: 149..236
e-value: 2.4E-15
score: 56.5
IPR001683Phox homologous domainPROSITEPS50195PXcoord: 135..243
score: 12.494
IPR036034PDZ superfamilyGENE3DG3DSA:2.30.42.10coord: 10..118
e-value: 1.3E-30
score: 107.4
IPR036034PDZ superfamilySUPERFAMILYSSF50156PDZ domain-likecoord: 8..115
IPR036871PX domain superfamilyGENE3DG3DSA:3.30.1520.10coord: 136..242
e-value: 5.1E-23
score: 83.1
IPR036871PX domain superfamilySUPERFAMILYSSF64268PX domaincoord: 126..238
NoneNo IPR availablePANTHERPTHR12431:SF19SORTING NEXIN-27coord: 12..497
NoneNo IPR availableCDDcd00992PDZ_signalingcoord: 19..111
e-value: 4.97794E-24
score: 93.7854
NoneNo IPR availableCDDcd01777FERM_F1_SNX27coord: 251..334
e-value: 8.31867E-10
score: 53.4579
IPR037831SNX17/27/31PANTHERPTHR12431SORTING NEXIN 17 AND 27coord: 12..497