Protocadherin alpha-2
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30026029 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 241.891 bits (616), Expect = 6.061e-65 Identity = 233/813 (28.66%), Postives = 372/813 (45.76%), Query Frame = 2
Query: 215 MDILKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDI-------EGLGINLEFHGSLIYKLSGPNCCFSIDQKS-SVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-LYEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMIC--EHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITN 2569
MD+L ++F + C +G +E Y I+E P + ++G + D+ + L ++F L+YK +G I++ + + T ID E +C C E+ V + + ++ +V++R + D+NDN P F I + E S S L A D D+ Q Y L + F L + + + P L + +LD E + Y++K++ + ++ + + + V D NDN P F + V + EN P + + QL A D D + + F +N R+LF + +I I LD E +K+ V +DG L AR+++ V V D ND P + I NP + + EN I + VTDKD + NG++ C +HE + F L + + L + T D E + + ++ L+ +D N S + +++ D NDN P F QS + EN G + KV+A D D G N KI+Y L D F +D TG++TV +DRE ++ Y I A D+G PL S+V + +++ D NDNSP + F V ENL T+G + D D G N+ V S NDD + + G + DRE ++ + V+ D G R SS +V I V+DVNDNKP I P P+ + +PG V+ Q+IAVD+D N ++ Y I+ NT +F+ + TG ++L + +G + + V D G P + +F + I N
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQEK--NYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQF--KLVYK-TGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHC-----FYEVEVAILPD-EIFRLVKIRFLIEDINDNAPLFPATVINISIPENS-AINSKYTLPAAVDPDVGINGVQ-NYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKD-ADHNGRVTCFTDHE-----IPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLN----QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG-RVSRSSSAKVTINVVDVNDNKPVFIVP-----------PSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT--RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP----DSLFSVVIVN 769 HSP 2 Score: 125.946 bits (315), Expect = 1.527e-28 Identity = 111/381 (29.13%), Postives = 179/381 (46.98%), Query Frame = 2
Query: 1475 FDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-----LTPFEFSV--RENLAPAT-IGQLQYEDSDIGRNADVV-FS-KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
DRE+ + + DG +S+ + V + D NDN P F++++ + EN P+GT + +++A D D G N KIH+S + S LF +++TTG+IT++ P+DRE ++KL + A D G +P + V +N+T DVNDN P + + P +V EN+ T I + D D N V F+ P + + L LD E+ + +++ D G QS+ + I+V D NDN P + ++SI SPG +T++ A+D D N K+ Y +L P+ P FS + TG L++ K L Y + KD+G PPL ++ I ++
Sbjct: 207 LDREEKDTYVMKVKVEDGGFP----QRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAM-LFIKVKDENDNAPVFTQ--------------SFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-LLGPDAPPE--FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQ 563 HSP 3 Score: 100.523 bits (249), Expect = 1.257e-20 Identity = 107/350 (30.57%), Postives = 154/350 (44.00%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPA--TIGQLQYEDSDIGRNADV--VFSKTWPNDDTVMITVNGT---LYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDAT-NTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F + + EN I + A D D G+NG +Y L ++ F L I++ G + VQ +DRE K+ Y + + D G +S+ L ++V D NDN P T E S+ EN AP ++ QL D+DIG NA + FS N + +N T + I +PLDRE H L V D GL R V + V DVNDN P + +R I + + S +I P LI V D DA N ++T + +P ++ S L L + Y IK+ D+G PPL M ++ + ++
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPEN-APVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPAR---AMVLVNVTDVNDNVPSI----DIRYIVNPVNDTVVLSENI-----PLNTKIALITVTDKDADHNGRVT--CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE 459
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Match: PCDH9 (protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661]) HSP 1 Score: 240.736 bits (613), Expect = 9.681e-65 Identity = 224/791 (28.32%), Postives = 361/791 (45.64%), Query Frame = 2
Query: 224 LKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEF--HGSLIYKLSGPNCCFSIDQKSS----VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
L+ +L + C ++ I + ++ Y I+E P + +G I D+ IN SL+Y+L + + SS + T + ID E +C +S + EL V + N +++++I V D NDN P F I + E + S + +ATD D Q Y L F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F V + EN P + + QL A D D S + +R+ ++LF++ +I + LD E +KV V +DG AR+ + + V D ND P + I +P + + E I + V+DKD + NGK+IC E P F L + + + Y + T + D E + + S ++ SD S N + + V++ D NDNPP F Q V+EN G + ++A D D G N I Y L + S F +D TGV+T DRE +E + + A D+G+ PL S + +TV D NDNSP F+F V ENL +T+G + D+D G N V S ND+ V+ +G + DRE + + V+ D G R S+ +V I V+DVNDN P +I+P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + +G + + V++ D G P
Sbjct: 3 LRDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAG---ASYAEENECFFELEVVILPN-DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFPIPSATDPDTGFNGVQ-HYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKD-TDVNGKVICFIEREVP---FHLKAVYDNQ---YLLETSSLLDYEGTKEFSFKIVASDSGKPSLN----QTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGG-QPPRSSTAKVTINVMDVNDNSPVVISP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNN--KGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 241.891 bits (616), Expect = 1.847e-64 Identity = 233/813 (28.66%), Postives = 372/813 (45.76%), Query Frame = 2
Query: 215 MDILKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDI-------EGLGINLEFHGSLIYKLSGPNCCFSIDQKSS-VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-LYEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMIC--EHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITN 2569
MD+L ++F + C +G +E Y I+E P + ++G + D+ + L ++F L+YK +G I++ + + T ID E +C C E+ V + + ++ +V++R + D+NDN P F I + E S S L A D D+ Q Y L + F L + + + P L + +LD E + Y++K++ + ++ + + + V D NDN P F + V + EN P + + QL A D D + + F +N R+LF + +I I LD E +K+ V +DG L AR+++ V V D ND P + I NP + + EN I + VTDKD + NG++ C +HE + F L + + L + T D E + + ++ L+ +D N S + +++ D NDN P F QS + EN G + KV+A D D G N KI+Y L D F +D TG++TV +DRE ++ Y I A D+G PL S+V + +++ D NDNSP + F V ENL T+G + D D G N+ V S NDD + + G + DRE ++ + V+ D G R SS +V I V+DVNDNKP I P P+ + +PG V+ Q+IAVD+D N ++ Y I+ NT +F+ + TG ++L + +G + + V D G P + +F + I N
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQE--KNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQF--KLVYK-TGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHC-----FYEVEVAILPD-EIFRLVKIRFLIEDINDNAPLFPATVINISIPENS-AINSKYTLPAAVDPDVGINGVQ-NYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKD-ADHNGRVTCFTDHE-----IPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLN----QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG-RVSRSSSAKVTINVVDVNDNKPVFIVP-----------PSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT--RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP----DSLFSVVIVN 769 HSP 2 Score: 125.946 bits (315), Expect = 2.031e-28 Identity = 106/354 (29.94%), Postives = 171/354 (48.31%), Query Frame = 2
Query: 1556 TSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-----LTPFEFSV--RENLAPAT-IGQLQYEDSDIGRNADVV-FS-KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
+S+ + V + D NDN P F++++ + EN P+GT + +++A D D G N KIH+S + S LF +++TTG+IT++ P+DRE ++KL + A D G +P + V +N+T DVNDN P + + P +V EN+ T I + D D N V F+ P + + L LD E+ + +++ D G QS+ + I+V D NDN P + ++SI SPG +T++ A+D D N K+ Y +L P+ P FS + TG L++ K L Y + KD+G PPL ++ I ++
Sbjct: 230 SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSA-MLFIKVKDENDNAPVFTQ--------------SFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-LLGPDAPPE--FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQ 563 HSP 3 Score: 99.7525 bits (247), Expect = 1.958e-20 Identity = 104/349 (29.80%), Postives = 154/349 (44.13%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADV--VFSKTWPNDDTVMITVNGT---LYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDAT-NTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F + + EN I + A D D G+NG +Y L ++ F L I++ G + VQ +DRE K+ Y + + D G +S+ L ++V D NDN P T E S+ EN T + QL D+DIG NA + FS N + +N T + I +PLDRE H L V D GL R V + V DVNDN P + + ++D S++I ++ + LI V D DA N ++T + +P ++ S L L + Y IK+ D+G PPL M ++ + ++
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPAR---AMVLVNVTDVNDNVPSIDIRYIVNPVNDTV--VLSENIPLNTKIA-------LITVTDKDADHNGRVT--CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE 459
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Match: PCDH9 (protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661]) HSP 1 Score: 240.736 bits (613), Expect = 2.595e-64 Identity = 224/791 (28.32%), Postives = 361/791 (45.64%), Query Frame = 2
Query: 224 LKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEF--HGSLIYKLSGPNCCFSIDQKSS----VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
L+ +L + C ++ I + ++ Y I+E P + +G I D+ IN SL+Y+L + + SS + T + ID E +C +S + EL V + N +++++I V D NDN P F I + E + S + +ATD D Q Y L F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F V + EN P + + QL A D D S + +R+ ++LF++ +I + LD E +KV V +DG AR+ + + V D ND P + I +P + + E I + V+DKD + NGK+IC E P F L + + + L + T + D E + + S ++ SD S L + + V++ D NDNPP F Q V+EN G + ++A D D G N I Y L + S F +D TGV+T DRE +E + + A D+G+ PL S + +TV D NDNSP F+F V ENL +T+G + D+D G N V S ND+ V+ +G + DRE + + V+ D G R S+ +V I V+DVNDN P +I+P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + +G + + V++ D G P
Sbjct: 3 LRDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAG---ASYAEENECFFELEVVILPN-DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFPIPSATDPDTGFNGVQ-HYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKD-TDVNGKVICFIEREVP---FHLKAVYDNQYL---LETSSLLDYEGTKEFSFKIVASDSGKPS----LNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGG-QPPRSSTAKVTINVMDVNDNSPVVISP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNN--KGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Match: PCDH11X (protocadherin 11 X-linked [Source:HGNC Symbol;Acc:HGNC:8656]) HSP 1 Score: 241.121 bits (614), Expect = 2.796e-64 Identity = 233/813 (28.66%), Postives = 372/813 (45.76%), Query Frame = 2
Query: 215 MDILKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDI-------EGLGINLEFHGSLIYKLSGPNCCFSIDQKSS-VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-LYEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMIC--EHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITN 2569
MD+L ++F + C +G +E Y I+E P + ++G + D+ + L ++F L+YK +G I++ + + T ID E +C C E+ V + + ++ +V++R + D+NDN P F I + E S S L A D D+ Q Y L + F L + + + P L + +LD E + Y++K++ + ++ + + + V D NDN P F + V + EN P + + QL A D D + + F +N R+LF + +I I LD E +K+ V +DG L AR+++ V V D ND P + I NP + + EN I + VTDKD + NG++ C +HE + F L + + L + T D E + + ++ L+ +D N S + +++ D NDN P F QS + EN G + KV+A D D G N KI+Y L D F +D TG++TV +DRE ++ Y I A D+G PL S+V + +++ D NDNSP + F V ENL T+G + D D G N+ V S NDD + + G + DRE ++ + V+ D G R SS +V I V+DVNDNKP I P P+ + +PG V+ Q+IAVD+D N ++ Y I+ NT +F+ + TG ++L + +G + + V D G P + +F + I N
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQE--KNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQF--KLVYK-TGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHC-----FYEVEVAILPD-EIFRLVKIRFLIEDINDNAPLFPATVINISIPENS-AINSKYTLPAAVDPDVGINGVQ-NYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKD-ADHNGRVTCFTDHE-----IPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLN----QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG-RVSRSSSAKVTINVVDVNDNKPVFIVP-----------PSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT--RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP----DSLFSVVIVN 769 HSP 2 Score: 125.946 bits (315), Expect = 1.927e-28 Identity = 106/354 (29.94%), Postives = 171/354 (48.31%), Query Frame = 2
Query: 1556 TSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-----LTPFEFSV--RENLAPAT-IGQLQYEDSDIGRNADVV-FS-KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
+S+ + V + D NDN P F++++ + EN P+GT + +++A D D G N KIH+S + S LF +++TTG+IT++ P+DRE ++KL + A D G +P + V +N+T DVNDN P + + P +V EN+ T I + D D N V F+ P + + L LD E+ + +++ D G QS+ + I+V D NDN P + ++SI SPG +T++ A+D D N K+ Y +L P+ P FS + TG L++ K L Y + KD+G PPL ++ I ++
Sbjct: 230 SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSA-MLFIKVKDENDNAPVFTQ--------------SFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-LLGPDAPPE--FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQ 563 HSP 3 Score: 100.138 bits (248), Expect = 1.929e-20 Identity = 106/349 (30.37%), Postives = 152/349 (43.55%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADV--VFSKTWPNDDTVMITVNGT---LYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDAT-NTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F + + EN I + A D D G+NG +Y L ++ F L I++ G + VQ +DRE K+ Y + + D G +S+ L ++V D NDN P T E S+ EN T + QL D+DIG NA + FS N + +N T + I +PLDRE H L V D GL R V + V DVNDN P + +R I + + S +I P LI V D DA N ++T + +P ++ S L L + Y IK+ D+G PPL M ++ + ++
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPAR---AMVLVNVTDVNDNVPSI----DIRYIVNPVNDTVVLSENI-----PLNTKIALITVTDKDADHNGRVT--CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE 459
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 157.147 bits (396), Expect = 3.034e-38 Identity = 179/665 (26.92%), Postives = 303/665 (45.56%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYK--LSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQF-SKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKI--LTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITV------NGTLYI--TKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL 2230
I EN I ++ T+ E G N + H S+ + G +ID + +T+ + ID + N +++ + G + L + V + I+V+D+ND+ P + Q++ E + G + A D D P N I+Y + E + F + + + LD E Y +K+ A + + + + D NDN P F+ ++V + E P S I L A D D + + + + A+ E+ + + G ++ +S L + H + +V + TD G + R V+ V ++D N +P +P +++ E+S IG ++T K + G R+ +S+ S + +I + DI + DRE + SV++ SD A+ L +S I V + D NDN P+F S Y A ++E+ P+GT L+V+A D D G NG + Y L S LF++D T+G + V +DRE L I A D G+ L+++ + +T+ DVNDN+P ++ + EN +P +T+G + D+D G NAD+ F + + D + + NG + I D E K + +G+ S+ V I V DVNDNKP L
Sbjct: 384 ILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGG----LTIDYSTGEVTLRERIDAK----NSPITAVIRAKDG---------AQPALSSTVPLTINVIDINDHAPTLIAAQKM--ITLEENVAIGEEVGRVYAIDEDSGP-NGIIKYSM-EGSEDFII---DEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRI-EEADREVFSILDIGDQGAILSVSGELKRQDH-KVRVEISATDQGGLQGRCVVNVFIDDVNS-APYFNDHPFSVKIPEHSP----IGYPVITLKAEDHDRGD--------NARIVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASD----HASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAEN-SPVGSTVGTIVARDADEGDNADISF-RIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKAN---KFFFELQASSGQLSSTVPVRIHVSDVNDNKPAL 1000 HSP 2 Score: 136.732 bits (343), Expect = 5.009e-32 Identity = 106/379 (27.97%), Postives = 173/379 (45.65%), Query Frame = 2
Query: 1409 EFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLT-PFEFSVRENLA-PATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
E L+ ++++L I TA++R + +++S T+ V +LD DN P F + YF + E+ PIGT +L V A DLD G NG+I YSL + +L I++ +GVI P+DRE +L + A D G+ S+ + ITV DVNDN+P + + ++ EN+ PA I ++ D D G N V +S + + T +T + K+ V +G S+ + I VID+ND+ P LI AA + I++ + G + ++ A+D+D N + Y + S+ F + +G + K L Y +KV+ +D G+P L
Sbjct: 221 EIRLAKSMDREVLDKHILKVTAYER-------------------VDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGKNLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTLRERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLI--------------AAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSM-----EGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSL 561 HSP 3 Score: 135.961 bits (341), Expect = 9.379e-32 Identity = 187/727 (25.72%), Postives = 311/727 (42.78%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQ--LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVT----DGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD---IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHD----FSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIG----QLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPS-QIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
F++D S + +AK++D E + H+ L V + V + A V + VLDV DN P F K + E + G+ + A D D + EN +IEY L E + L ++ + + LD E + + + A + K+ + V++ V D NDN P F S ++V + EN ++I + A D D + + +++ + L G V L ER P+ DG A S L + D +P LI +I + EN G +G+V D +DS NG +++S+ G I+ D I+T DRE +++ S+ + D S N +S TI V + D NDN P F + +Y ++E P G+ I+ + A D D+ + KI Y +E FS+ I +++V G + R+ ++ I A D G L +N+ +DDVN PF + E+ + IG L+ ED D G NA +V+S D + ++ G + ++ LDRE + + V D+ + +S ++ + + D+NDN P+ ++S AA+ S I V G Q+ A+D D N + Y + ++ PS Q+F + T+G L + L + + +D G+P L
Sbjct: 213 FTLDTMSGEIRLAKSMDREVL-------------DKHI-LKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDA-PIGTTVLSVFARDLD-SGENGEIEYSLGEGNGKNLLAINA-KSGVIQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTL------RERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAID-EDSGPNGI-----------IKYSME-GSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLN----TSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE--DQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQ-DHKVRVEISATDQGG--LQGRCVVNVFIDDVNSAPYFNDHPFSVKIPEH---SPIGYPVITLKAEDHDRGDNARIVYSI----DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHA-SPPLNTSTQIEVILDDINDNSPQFT----------SSSYAATISEDIPV----GTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSL 872 HSP 4 Score: 124.405 bits (311), Expect = 3.108e-28 Identity = 172/723 (23.79%), Postives = 307/723 (42.46%), Query Frame = 2
Query: 302 IQENEPI------------DRMVGTIATDIEGLGINLEFHGSLIYKLSGPNC--CFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD---GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVF----SKTWPNDDTVMI-TVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHIL 2392
+Q+N PI D +GT + ++ +G + Y L N +I+ KS V+ A +D E++ + R L++I + + + V I+V+DVNDN P F+ + E + + I ATD D N ++ Y +A L +D + L +DA+N + IRA + + + + + V D ND+ P ++ + ++EN + ++ A D DS ++++ + E + F + ++ +I + LD E RY + V D + + V+++D ND +P + + + E +G I + D D+ Q K+ E + + L G IL+ K + ++ V + +D L +NV I D N + P F + + E+ PIG ++ + A D D G N +I YS++ F+ID ++G I+V +DRE + + + + A D S PLN+S + + +DD+NDNSP + + ++ E++ T Q+ D+DIG N V + S + P+ + +GTL ++ LDRE L + RD G +S E+ + + DVNDN P T S + I+ G + ++A D D+ N +++ I
Sbjct: 263 VQDNSPIFEKDSYFGEIREDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGKNLLAINAKSGVIQTAAPLDRETLSLIR------------LDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILE-NITIPAVIATVKATDEDFG-TNGKVHYSMASSSGIGGLTIDYSTGE-VTLRERIDAKNSPITAV-IRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSM------EGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ---KITYRIEEADREVFSILDIGDQGAILSVSGELK-----RQDHKVRVEISATDQGG------LQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS-QFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAAS-EITLTLSDVNDNAP--------------TFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIF 932 HSP 5 Score: 79.7221 bits (195), Expect = 1.497e-14 Identity = 78/276 (28.26%), Postives = 128/276 (46.38%), Query Frame = 2
Query: 1601 NPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-----EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFS-VRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMI--TVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQS---PGYVITQLIAVDDDDATNTKLTYHI 2389
N F+Q +Y + E+ PI T+I V A + ++YS+ +LF +D+ +G I + +DRE+ + + L + A + +++S + + V DV DNSP F +RE+ AP T+ + D D G N ++ +S N ++ +G + PLDRET L V D G +R+S+ V I V+DVNDN P AS S ++++ ++ P VI + A D+D TN K+ Y +
Sbjct: 161 NAVHFQQEKYVKELPEDTPIETIIASVKA---SHASSQPLYYSMVAPQDSRSQNLFTLDTMSGEIRLAKSMDREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIRED-APIGTTVLSVFARDLDSGENGEIEYSLGEGNGKNLLAINAKSGVIQTAAPLDRETLSLIRLDVIASDKG-TPKRESTAMVEITVVDVNDNAPVF----------------ASDSYNVTILENITIPA-VIATVKATDEDFGTNGKVHYSM 414 HSP 6 Score: 78.1814 bits (191), Expect = 3.755e-14 Identity = 81/350 (23.14%), Postives = 151/350 (43.14%), Query Frame = 2
Query: 824 NDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD---GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD----------IRTKTAFDRE-KSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYK 1825
+DLD E++ + + + A + +++ +DD NDN P+F SS ++ + E+ P + Q+ A D D ++ + L +++++ +LF + + + +SS LD E+ +P+F D A S + + + D ND +P Q + + ENS G +G ++ D D E + F + G + K+ + I T+ FD E K+++ L S G L+S+ + + + D NDN P + + +N + I + A+D D N + Y LE + L + + TG I V+ R + +K
Sbjct: 740 SDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDAD------------EGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSG-------QLSSTVPVRIHVSDVNDNKPALKDFVILMNRFDNVQMARQIGFIPAFDPDQ--NATLEYFLEEN-DLIEAEKYTGKILVKQEWKRNMDVSFK 1067
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 156.377 bits (394), Expect = 4.801e-38 Identity = 179/665 (26.92%), Postives = 303/665 (45.56%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYK--LSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQF-SKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKI--LTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITV------NGTLYI--TKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL 2230
I EN I ++ T+ E G N + H S+ + G +ID + +T+ + ID + N +++ + G + L + V + I+V+D+ND+ P + Q++ E + G + A D D P N I+Y + E + F + + + LD E Y +K+ A + + + + D NDN P F+ ++V + E P S I L A D D + + + + A+ E+ + + G ++ +S L + H + +V + TD G + R V+ V ++D N +P +P +++ E+S IG ++T K + G R+ +S+ S + +I + DI + DRE + SV++ SD A+ L +S I V + D NDN P+F S Y A ++E+ P+GT L+V+A D D G NG + Y L S LF++D T+G + V +DRE L I A D G+ L+++ + +T+ DVNDN+P ++ + EN +P +T+G + D+D G NAD+ F + + D + + NG + I D E K + +G+ S+ V I V DVNDNKP L
Sbjct: 25 ILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGG----LTIDYSTGEVTLRERIDAK----NSPITAVIRAKDG---------AQPALSSTVPLTINVIDINDHAPTLIAAQKM--ITLEENVAIGEEVGRVYAIDEDSGP-NGIIKYSM-EGSEDFII---DEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRI-EEADREVFSILDIGDQGAILSVSGELKRQDH-KVRVEISATDQGGLQGRCVVNVFIDDVNS-APYFNDHPFSVKIPEHSP----IGYPVITLKAEDHDRGD--------NARIVYSIDSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASD----HASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAEN-SPVGSTVGTIVARDADEGDNADISF-RIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKAN---KFFFELQASSGQLSSTVPVRIHVSDVNDNKPAL 641 HSP 2 Score: 116.316 bits (290), Expect = 9.114e-26 Identity = 151/613 (24.63%), Postives = 266/613 (43.39%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD---GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVF----SKTWPNDDTVMI-TVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHIL 2392
V I+V+DVNDN P F+ + E + + I ATD D N ++ Y +A L +D + L +DA+N + IRA + + + + + V D ND+ P ++ + ++EN + ++ A D DS ++++ + E + F + ++ +I + LD E RY + V D + + V+++D ND +P + + + E +G I + D D+ Q K+ E + + L G IL+ K + ++ V + +D L +NV I D N + P F + + E+ PIG ++ + A D D G N +I YS++ F+ID ++G I+V +DRE + + + + A D S PLN+S + + +DD+NDNSP + + ++ E++ T Q+ D+DIG N V + S + P+ + +GTL ++ LDRE L + RD G +S E+ + + DVNDN P T S + I+ G + ++A D D+ N +++ I
Sbjct: 2 VEITVVDVNDNAPVFASDSYNVTILE-NITIPAVIATVKATDEDFG-TNGKVHYSMASSSGIGGLTIDYSTGE-VTLRERIDAKNSPITAV-IRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSM------EGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQ---KITYRIEEADREVFSILDIGDQGAILSVSGELK-----RQDHKVRVEISATDQGG------LQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSS-QFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAAS-EITLTLSDVNDNAP--------------TFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIF 573 HSP 3 Score: 114.005 bits (284), Expect = 4.953e-25 Identity = 147/562 (26.16%), Postives = 243/562 (43.24%), Query Frame = 2
Query: 914 VDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVT----DGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD---IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHD----FSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIG----QLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPS-QIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
V++ V D NDN P F S ++V + EN ++I + A D D + + +++ + L G V L ER P+ DG A S L + D +P LI +I + EN G +G+V D +DS NG +++S+ G I+ D I+T DRE +++ S+ + D S N +S TI V + D NDN P F + +Y ++E P G+ I+ + A D D+ + KI Y +E FS+ I +++V G + R+ ++ I A D G L +N+ +DDVN PF + E+ + IG L+ ED D G NA +V+S D + ++ G + ++ LDRE + + V D+ + +S ++ + + D+NDN P+ ++S AA+ S I V G Q+ A+D D N + Y + ++ PS Q+F + T+G L + L + + +D G+P L
Sbjct: 2 VEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDYSTGEVTL------RERIDAKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAID-EDSGPNGI-----------IKYSME-GSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLN----TSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE--DQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQ-DHKVRVEISATDQGG--LQGRCVVNVFIDDVNSAPYFNDHPFSVKIPEH---SPIGYPVITLKAEDHDRGDNARIVYSI----DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHA-SPPLNTSTQIEVILDDINDNSPQFT----------SSSYAATISEDIPV----GTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSL 513 HSP 4 Score: 77.7962 bits (190), Expect = 4.380e-14 Identity = 81/350 (23.14%), Postives = 151/350 (43.14%), Query Frame = 2
Query: 824 NDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD---GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD----------IRTKTAFDRE-KSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYK 1825
+DLD E++ + + + A + +++ +DD NDN P+F SS ++ + E+ P + Q+ A D D ++ + L +++++ +LF + + + +SS LD E+ +P+F D A S + + + D ND +P Q + + ENS G +G ++ D D E + F + G + K+ + I T+ FD E K+++ L S G L+S+ + + + D NDN P + + +N + I + A+D D N + Y LE + L + + TG I V+ R + +K
Sbjct: 381 SDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDAD------------EGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSG-------QLSSTVPVRIHVSDVNDNKPALKDFVILMNRFDNVQMARQIGFIPAFDPDQ--NATLEYFLEEN-DLIEAEKYTGKILVKQEWKRNMDVSFK 708
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Match: cdh-4 (Cadherin-4 [Source:UniProtKB/TrEMBL;Acc:A0A1C3NSI5]) HSP 1 Score: 125.176 bits (313), Expect = 1.809e-28 Identity = 165/687 (24.02%), Postives = 286/687 (41.63%), Query Frame = 2
Query: 578 AVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWN-ELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILT------YDIRTKTAFDREKSSQISV-VLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIG----TVILKVNAYDLDDGLNGKIHYSLEHDFS-LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPATIG-QLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTL----PSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
A+ V + + DVNDN P F ER G+ + + +A D D +P + +I + L E + F L + +L + + LD E HY + RA D +N +L + V D ND+PP+F F++ + + P+ S I D D + + NE +F + N ++L + E +Y++ V DG++E + +++ ++ D + + + + ENS KG V+ + E P + F LS + ++ D EK+ Q+ L D + I V I + NDN PK + + EN P I ++ A D D +I + + DF LFQID GV+TV P+D E+ + L + A D + +TV D NDN+P + + V E+ +IG +L + + G + + P+D T + +N G L + KPLD ET L V +D+G+ ++ +V I V+D NDN P+ + + ++ + + G + + A+D D ++Y + + + P F+ NS G + + + + + I Y +KV KD G PPL E + + + ++
Sbjct: 2694 AITTVTVDIGDVNDNAPAFHGD-YERFTISEDAAVGTSVTIFSAMDRDDSP-SGRIRFSLVEENPYFDL---NENSGWLTVASQLDREKIDHYKLIARA---TDEGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDL--HLPSTSPILHFSIKDDDLSPNNVSQFFIPKGNE-EGVFWIDSNNDLLLKRPEI-VENKMQYQLKVTAFDGVFETSTKVKINLKSSKDSDIRCPEANKTVILAENSKKGTVV-----------------LGESSLLGPNVTFKLSDNDGNVFVVNFRNGIVKVKESDQIDYEKNQQLEFHRLTIQDNSEVCKEL-------ITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDAD---FDEIKFRMVDDFGGLFQIDDINGVVTVVKPLDSEILGFFNLTVVASDG---EFEDKATILVTVIDQNDNAPTFEKSTYSMKVMES---ESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPL-ETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKS--------------GEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSN-GDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDE 3319 HSP 2 Score: 117.087 bits (292), Expect = 6.649e-26 Identity = 120/472 (25.42%), Postives = 213/472 (45.13%), Query Frame = 2
Query: 830 LDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL---YEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQY--EDSDIGRNADVVFSKTWPNDDTVM-ITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPR 2227
L+ Y I + +A + ++ L L V D ND PP F +S + E+ + + A D D + + L + ++ FSV I ++ L+++ + + TD + A + +EV + E+ + P+ + + VME++ G VIG+V + + + ++ E ++ L FS+ K I+ K++ DRE+ +Q + + + + +H + T+ V I D NDN P F ++E+ +GT + +A D DD +G+I +SL + F ++ +G +TV +DRE +HYKL A D G N+ + I V DVND SP EF++ +L P+T L + +D D+ N F N++ V I N L + +P E K ++ L+V +G ++S +V I + D+ R
Sbjct: 2465 LNYHRDKRYQIPLVVEDATGRRAFSTLT--LSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDENDTIEYSLLDGSESQF---FSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIV------KSSLDRERKNQWKMTIRA----DAAGGVHAIT--TVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEENPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEGG--FNTDLPFTIVVSDVND-SPPQFEKEEFNIDLHL-PSTSPILHFSIKDDDLSPNNVSQFFIPKGNEEGVFWIDSNNDLLLKRPEIVENKMQYQLKV----TAFDGVFETSTKVKINLKSSKDSDIR 2911 HSP 3 Score: 115.546 bits (288), Expect = 1.656e-25 Identity = 189/766 (24.67%), Postives = 325/766 (42.43%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNC-CFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSW---LDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIE---------VMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD----IRTKTAFDREKSSQISVVLICSDG-WNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGK---IHYSLEHD--FSLFQIDSTTGVITVQG--PVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPF-EFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKD 2515
+ E+ PI +V + + E G N F +I+ ++G + ++D++S +T+A DL + + D ++ + S+V+ + ++ + DVN++ PQF + +SE + K G IF TA D D N +I++ L + + + + + LL LD E+Q + I A + + + N+ + V+D NDNPP+ + E+ P + + + A D D S L+F L N + F + + I I + LDY + + + + V D S L + + N IE V ENS G +VI+ + ++ K+ E+ LE+ + G + D +RT DRE S + + D + + + ++ILD ND+ P ++ Y A VAEN P VI+KV A D DD N + + +E S F+ID T+G IT G +DRE + ++L + D G L S+V + + V D NDNSP +SVR A + ++ D+D G NA + ++ T D I NG + ++ + + + + L V+ D+G G++ ++ V + + KPR + + + + I IS G + +L A DA +L + I + P +F TG L L K + G + +SV D
Sbjct: 617 VTEDAPIGTVVAKLQANDEDTGYN-GFIRYVIHDIAGSSHEVLTVDEQSGEITVAS--DLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTM-----KLRIKDVNNHSPQFDEVSYYLRISE-NEKPGKDIFKVTANDFD-GGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLL-----NSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELV----DIAHNHLAIEFDDVAKEASVYENSEIGT---EVIMIEAKETGDEQKVKAEN------LEYRIIGGDGWPHFSIDQKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQAIHHYSVRSKFA-GKLCRIFAVDADEGENARLTYNIT-EGDARFSIDNNGNIIASEAIHGD--ESYALTVQATDHGTPGQQFAATRVVL-TANSAGQKPR----KSKNSPPEISGKKSDYVIPISDADQVGLTVGKLEA---SDADGDELWWSISSGD--PDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTD 1340 HSP 4 Score: 102.449 bits (254), Expect = 1.699e-21 Identity = 121/444 (27.25%), Postives = 197/444 (44.37%), Query Frame = 2
Query: 884 QDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTP----ARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFS-LSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLE------HDFSL--FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSP----CLLTPFEFSVRENLAPATIGQ--LQYEDSDI-GRNADVVFSKTWPNDDTVMITVNGTLYI--TKPLDRETKDRHCLRVRLRD 2149
QDN + + + + +++ NDN P+ L V + EN P AR I +++A D D + +F + ++ LF + V+ + LD E + + V +DG +E ++ + V V D+ND +P ++ ++VME+ G + + D ++ET E L+ S ++S N T + D E S + + ++ D S L + + + ++D NDN PKF + +Y V EN G +L V A D+D G + Y LE D + F I+S V+ Q +D E + Y L + A D G PL S L I V+D ND++P C +T V+E A IG L++ SD+ G F+ D VN L + K L+ KD++ L V +D
Sbjct: 2987 QDNSEVCKELITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYITRIVAEDADFDEI-KFRMV----DDFGGLFQIDDINGVVTVVKPLDSEILGFFNLTVVASDGEFEDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGD----------QNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKD----SGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDVLISQS-IDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTAL---VQEGEA---IGHRLLKFSVSDLDGPKNGAPFTVEIQGDGAKSFKVNEKLELLTAKKLEYRKKDKYLLTVIAKD 3404 HSP 5 Score: 92.4337 bits (228), Expect = 1.674e-18 Identity = 79/270 (29.26%), Postives = 133/270 (49.26%), Query Frame = 2
Query: 1256 SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSF-TINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSV-GLNITVDDVNDNSP-CLLTPFEFSVRENLA-PATIGQLQYEDSDIGRNADVVF 2029
SP P ++EV E++ G V+ ++ D +D+ NG + R +G + ++LT D I + + ++ V+ + A + SS T+ ++I D N++ P+F + Y+ ++EN G I KV A D D G NGKI +SL + S+ ID+ TG++ + +DRE ++ + I A D G P+ SV L I+V+DVNDN P C++ + E+L A + + D DIG+N+ + F
Sbjct: 605 SPVFSSFPEIVEVTEDAPIGTVVAKLQAND-EDTGYNGFI---------RYVIHDIAGSSHEVLTVDEQSGEITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEG-FPMRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKF 863 HSP 6 Score: 84.3445 bits (207), Expect = 5.397e-16 Identity = 172/759 (22.66%), Postives = 303/759 (39.92%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLES-ICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARS--MIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDR----EKSSQISVVLICSDG---WNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVG---LNITVDDVNDNSPCLLTPF-EFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMI----TVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSF---NSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFIT----NKPA----KYDDKLQSNN 2608
FS+ + +T+AK ++ ++ + ++ + + S+ H A V +++ + +P+FS V E + G+ I +T+I I G +E SF ++ + + + LD E + + + IRA A + VD + D NDN P F+ + E+ + IF + D + +RF L E F + +N + ++S LD E+ YK+ TD G + ++V D ND PQ + I++ S ++ + D D S N +F + G + + D R E Q + + DG +T I+L SS +++ + N +AEN GTV+L ++ L + + L ++D ++F ++ G++ V+ + +++ +L H + +I NS V + + ++++NDN P ++ + S+ ENL P + QY + +AD K DD + +NG + + KPLD E L V D G + + + VID NDN P T ++ S+ + +S GY + A D N + Y++ PS + SF N+ TG L+L KPL + + V KDSG PPL E + + N P KY K++ N+
Sbjct: 2551 FSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHH-------------ATTTVEVNIASESVKVPRFSNSHYLFSVMEDA-DVGNVIGRVQQMETEIDEIRFTIVPG-SEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIRADAAGGVHAITTVTVD--IGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLV-----EENPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEGGFNTDLPFTIVVSDVNDSPPQFEKEEFNIDLHLPSTSPIL--HFSIKDDDLSPNNVS------------QFFIPKGNEEGVFWIDSNNDLLLKRPEIVENKMQYQLKVTAFDGVFETSTKVKINLKSSKDSDIRCPEANKT----------VILAENSKKGTVVLGESSL-----LGPNVTFKLSDNDGNVFVVNFRNGIVKVKESDQIDYEKNQQLEFHRL---TIQDNSEVCKELITVVIENLNDNRPKIIEKLLKVSIDENL-PTSEDARQYITRIVAEDADFDEIKFRMVDDFGGLFQIDDINGVVTVVKPLDSEILGFFNLTVVASD----GEFEDKATILVTVIDQNDNAP--------------TFEKSTYSMKVMESESIGYELAHFRASGGDQ--NETIEYYLK-----PSDVTSFVNLNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENS 3229 HSP 7 Score: 83.1889 bits (204), Expect = 1.143e-15 Identity = 151/687 (21.98%), Postives = 279/687 (40.61%), Query Frame = 2
Query: 569 QLLAVVRVRISVLD-VNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPY---LFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFD----LYQTANNELRKLFSVLQNGTVILISSWLDYE----RHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS--PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLS------SGKNKKILTYDIRTKTA---------FDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITV---NGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSG 2521
+++A +V I V + + P F K + E++ G + AT +D EN IEY L+ D + P + + LD E Y +K+ A + + +E + ++D ND P F S S + ++ I + A D D+T+ L + LY+ + + LF++ + ++ ++ + + + V VTDG++ A + L V + P+ Q+ V +EN+ +V ++T G + P L+FSL+ S +K+ I KT + R+K QI +V+ + G + T+ + ++D ND PP F Y ++E+ G ++ V+A D D+ N I YSL + F + G ITV ++ + L I A DS + P +++ + + + + P + + FSV E+ IG++Q +++I + + +D + +V G + + LDRE K++ + +R G + V + + DVNDN P + +IS + G +T A+D DD+ + ++ + ++ N F N +G+L++ L I HY + D G
Sbjct: 2164 KMIAKAQVEIIVKSGITTHAPVFEKLKYTASTPEST-SIGQRLLTIKATTSD---ENDTIEYSLSGSK-------DIEIHPETGDVTITGQLDYEKTQKYDLKLVA-TSSGKQVSSEAEFIVLIEDVNDEMPEFIRSDVSAKISDSAITGQFITIMSATDMDTTNSLDEESQKLLYKIVDGD-ETLFNISPATGELSLARPVEQDDLVNEDTKKVLNVSVTDGMFTAYAKLVVEILRSGSMQPPPRFEQSHYVANALENT---IVNKSALLT----VAVKGGV--------PPLQFSLAPTTSSNSSTSKEAWPVAIDRKTGRIHVSRVLNYHRDKRYQIPLVVEDATGRRAFS--------TLTLSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDDE--NDTIEYSLLDGSESQFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIRA---DAAGGVHAITTVTVDIGDVNDNAPAF--------------HGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEENPY----FDLNENSGWLTVASQLDREKIDHYKLIARATDEG 2791 HSP 8 Score: 83.1889 bits (204), Expect = 1.330e-15 Identity = 170/755 (22.52%), Postives = 308/755 (40.79%), Query Frame = 2
Query: 392 LIYKLS--GPNCCFSIDQKSSVLTIA--KNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGS--HIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTH----YLIKIRAWN-AQDNKQWNELNVDLYVDDF-------NDNPPRFNS--SLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGK-------MICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYK--LHIHAVDSGSIPLNSSVGLNI-TVDDVNDNSPCLLTPFEFSVRENLAPAT----IGQLQYEDSDIGRNADVVFSKTWPNDDTVMI-TVNGTLYITKPLD--RETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKP---RLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPP 2530
L++K+ P F ID S +T + + +D E + S C G+ QL + V V ++VLD NDN P F+ Q I H S S AG IF A D D ENA++ Y + E F + D ++ A H Y + ++A + +Q+ V L + ++PP + S + + + + + +L A+D D + + ++ + +F V Q+ +L++ ++ + ++ + VTDG S + + V + + P+ + +V E + +G I T K ++ G + E ++ SSG ++ D E + +I V+ AN+ ++F++N+ D NDN P F FA V E+ + V+ V A+D D G NG + YS+ ++ SLF+ID+ +G + + P+D EL +H + L I A+DS + L + L+I ++ + + ++ ++ ++ P T + L + V K PN + T++G +++ L + K C + G +Q +V ++I N + P R + +RE P S +S S+ V++ A+D+D +N + Y +L P Q+FS + +G + + Y V D G PP
Sbjct: 1084 LMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEP------------QLCSNVIVIVNVLDENDNSPTFT-QAI-HHYSVRSKFAGKLCRIF---AVDADEG-ENARLTYNITEGDARFSI--DNN--------GNIIASEAIHGDESYALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEISGKKSDYVIPISDADQVGLTVGKLEASDADGDELW----WSISSGDPDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQAWDHSTVIIQVSRQISQRPKFSASHYQTDVSER----VAVGTQIYTLKASGESLGTKPLVFNLFSVDDVAMEDKIRVEPSSG--------NVIVMEPLDYEAARRIRAVVQVQ-----QANMKSFATFSVNIN--DENDNSPYFVGHTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEVRLAKPLDPEL-QHVESILRIRAIDSAANSLKDEMSLHIRNSNEAPETAKFDRKVYQTTLYDSTRPGTPVLVLNALHH---------GTVSYKLEPNCTFFEVHTLSGAVHLATWLTKLKHRKSVECTAIVESTEG----QQDIAKVIAKIIRTNQHSPIFRRQVYRGTIRE----NMPTGSSVLSKSLLP---LVVS---AIDEDPGSNGLVGYRMLSPKD--EQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQPP 1761 HSP 9 Score: 70.8626 bits (172), Expect = 6.955e-12 Identity = 95/406 (23.40%), Postives = 170/406 (41.87%), Query Frame = 2
Query: 1406 LEFSLSSGKNKKI--LTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLD-----DGLNGKIHYSL-EHDFSLFQIDSTTGVITVQGPVDRE-------------------LKEHYKLHIHAVDSGSIP----LNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPP 2530
+E+SLS K+ +I T D+ D EK+ + + L+ TS+ ++S V I D ND P+F +S A ++++ G I ++A D+D D + K+ Y + + D +LF I TG +++ PV+++ + KL + + SGS+ S + +++ N LLT +V+ + P LQ+ + + + WP + G +++++ L+ R+ + + + D GRR S + + VID+ND P + P S SIS G + + A DDD+ N + Y +L + SQ FS + G +++ K L H + + DS +PP
Sbjct: 2219 IEYSLSGSKDIEIHPETGDVTITGQLDYEKTQKYDLKLVA-----TSSGKQVSSEAEFIVLIEDVNDEMPEFIRSDVSAKISDSAITGQFITIMSATDMDTTNSLDEESQKLLYKIVDGDETLFNISPATGELSLARPVEQDDLVNEDTKKVLNVSVTDGMFTAYAKLVVEILRSGSMQPPPRFEQSHYVANALENTIVNKSALLT---VAVKGGVPP-----LQFSLAPTTSSNSSTSKEAWP---VAIDRKTGRIHVSRVLNYHRDKRYQIPLVVED--ATGRRAFS-TLTLSVIDINDKPPFFVLP--------------FYSTSISESAKEGDTVMMVSATDDDE--NDTIEYSLL--DGSESQFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPP 2587 HSP 10 Score: 63.5438 bits (153), Expect = 1.127e-9 Identity = 84/315 (26.67%), Postives = 131/315 (41.59%), Query Frame = 2
Query: 275 IKECVLKYLIQENEPIDRMVGTIATDIEGLGINL-EFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDST--SVLRFDL---YQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG 1201
I E +LK I EN P T I + E ++ G F ID + V+T+ K +D E + G L V + S+ + + ++V+D NDN P F K V E S G + A+ D +N IEY L + + L+ Q L L LD E + + + A ++ E V++ V D NDN P+F + VKEN+ + + + A D DS + ++L +T + F++ NG V LIS +DYE+ ++Y + V DG
Sbjct: 3011 IIEKLLKVSIDENLPTSEDARQYITRIVAEDADFDEIKFRMVDDFGG---LFQIDDINGVVTVVKPLDSEIL--------------GFFNLTV-VASDGEFEDKATILVTVIDQNDNAPTFEKSTYSMKVME-SESIGYELAHFRASGGD---QNETIEYYLKPSDVTSFVNLNAQTG-ILTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETTTDTPVLPFAINSNGDV-LISQSIDYEKIKKYNLKVIAKDG 3301 HSP 11 Score: 57.7658 bits (138), Expect = 7.280e-8 Identity = 44/161 (27.33%), Postives = 70/161 (43.48%), Query Frame = 2
Query: 1469 TAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILK-------VNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVG--LNITVDDVNDNSP 1918
T KS + + ++ ++G A + +I+ N + P FR+ Y + EN P G+ +L V+A D D G NG + Y + D +F +D +G I Q D E + Y ++ A D G P S + + +TV D ND P
Sbjct: 1630 TKLKHRKSVECTAIVESTEGQQDIAKVI--------AKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRMLSPKDEQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPP 1782 HSP 12 Score: 53.9138 bits (128), Expect = 9.255e-7 Identity = 102/443 (23.02%), Postives = 185/443 (41.76%), Query Frame = 2
Query: 938 NDNPPRFNSSLFSVLVKENTPARS---------MIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEAR-----SXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENG--PIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQG-PVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITK--PLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVID 2206
N + P F ++ ++EN P S ++ I DP S ++ + + + ++ FSV Q I D+E+ + Y V D R S++ V V DENDE P+ N I ++ + G+ +G D D + I + + FS+ S K +L D + D K + V + +DG ++ S+ + + + ++ KF +++Y + EN P G++IL V + D L+ H+S+ + F I TGVI+ G +DRE +L + A P+ + + + ++++ND +P + TP++ ++ + IG + E I + V + + N V G + + K P E ++ +DNG R + V IRV+D
Sbjct: 1664 NQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRMLSPKDEQM---FSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPPRFPSNSLDISMILPTANGVSVGGQTAQDMDSVGSLRYFIKDQS-----VPFSVDS-KTGDVLVKD--SNGISDMTKLFDLEVFV--TDGKQSA-------SYVMKISTISTENSKFKFTRNEYHTSLIENTTLPPGSIILSVAT--IGDKLD---HFSIVNPHEAFFIHPGTGVISSSGIALDREKSAIIRLVVQAKSHEKNPVMARALVVVGIENINDETPIFMGTPYDITI----GHSDIGTVVLEPKVIDNDEGDVVTISSENMPEYFKIVGGKVVLGKKLPSIEEEDLEFNFKLIAKDNGSVHRVEEP--VKIRVVD 2075 HSP 13 Score: 51.2174 bits (121), Expect = 6.691e-6 Identity = 69/341 (20.23%), Postives = 138/341 (40.47%), Query Frame = 2
Query: 431 IDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPY-------LFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIAND---PDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARS-XXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKM---ICEHETTEPRLE 1411
++ ++ +LT+AK +D E++ + SG LE +V ISV+D NDN P+F K++ V E S K+G + A D D + + Y L + D P+ + + +D E Y +K+ A + +E ++++V+D ND+ P F+ + LV+E + + +D P + + ++ + + +L + L+Y + +Y + V D + L + + + +P + I ++N +IG++ +D+D+ NG + + E PR +
Sbjct: 3161 LNAQTGILTLAKPLDFETLSALKLTVVAKDSGVPPLE------------TEAQVEISVMDENDNAPKFEKEKYVGKVKENS-KSGEKVLTVKALDVD-SEHFGAVSYEL---EIVSETTTDTPVLPFAINSNGDVLISQSIDYEKIKKYNLKVIAKDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLDGPKNGAPFTVEIQGDGAKSFK-----VNEKLELLTAKKLEYRKKDKYLLTVIAKDVKGKTTDCPLTIFIRQTSRHAPTMKPMKIQINTLQNELPEGIIGRLKASDEDEEDQNGLLRFGLVEGSIQSPRAQ 3479
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Match: cdh-1 (CaDHerin family [Source:UniProtKB/TrEMBL;Acc:Q5F4W0]) HSP 1 Score: 116.316 bits (290), Expect = 8.415e-26 Identity = 163/665 (24.51%), Postives = 283/665 (42.56%), Query Frame = 2
Query: 596 ISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS-PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWN----TSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-----EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSS--VGLNITVDDVNDNSPCLLTPF-EFSVRENLA---PATIGQLQYEDSDIGRNADVVFS--KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPP 2530
+++ D+NDN PQ+ +I H+S + GS TA D D+ +N I Y + + +L + +F+ N +D + ++RA + +L V + D PP+F +L+ V + E+TP + + +++AN+ ++ +R+ L N+ L +GTV I D+E+ + Y+ V T+ E + L + + +++ P N + V E + V +D D S T G+ + H +E SS + +T ++ + R + +V+ DG SANIH+T ++D + P+F +S+Y E+ G I V A K+ YS+ +H+FS ID TG I V +D ++ + L+I A ++P S + I ++D NDN P + E S+RE+L P + +Q D D +N +V +S + P + G L LD E + LRV+ D G+ R S+ + I V+DVNDN P E+ + + P ++ +++A D D N ++ Y I T S+ F + G + + + I H I + +D G PP
Sbjct: 429 LTIGDINDNAPQWHSSQI--HISLNRTQGGSRTL--TAKDPDLG-QNGWIRYSVLDT----ELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSL----QNQDEHLTVDTMSGTV-CIQKTFDFEKQKSYQTTVIATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMD-SGTFGE-VSYHILSE-------SSSFSINPVTGEVFAQKPLAR---GRFHLVVSAKDGGGQSSENSANIHIT--------VIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAM-------SKVKYSIYSGDQDHNFS---IDEDTGKIYVTRYLDADVHDTVLLNIQA----TLPSGESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYV--VQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPR-SSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKT--------------IVGKVVARDKDSLENGQIVYRI----TNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPP 1024 HSP 2 Score: 105.531 bits (262), Expect = 1.599e-22 Identity = 162/664 (24.40%), Postives = 275/664 (41.42%), Query Frame = 2
Query: 584 VRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKS--FQLC---LDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQL----IQNPSVIEVMENSGKGLVIGQVIVT----DKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISV-VLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSG 2521
+ + + V D NDN P F+ Q ++ +SE + + G+ L T TD D P+ + + + + + F+L +++Q Q L + LD E + Y + I A + + +L + + D NDN P F+ S ++ V N S + + A D D S + +D+ +T+ F++ Q+G + +S L H V + +V+ + V SP L + + +MENS G ++ +V + D +C +T + + L G DRE +S+ + L+ DG + L + I D NDN P++ SQ H++ N G + A D D G NG I YS+ D L ID TG I V +D + K + A D GS L++ + + + D P ++ + E+ T + ++ +S G + + +S ++ + T++GT+ I K D E + + V + N S+ + IR+ DVNDN P + + P + P V++ A D D T +++YHIL S FS N TG + KPL+ G + + VS KD G
Sbjct: 106 IDILVEVDDENDNAPSFADQVVKLEISEFA-QLGTSFALPTVTDGD-GPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPS-NSNFAISQSGVITTTASLLPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENSTLGSIVARVSIAQQYRDTKLRLIGSSALCPQQTDQAHVYLLLLCG--------------ILDRETASEHHLKFLLEKDGQIIIEHPQL-------LTIGDINDNAPQWHSSQI--HISLNRTQGGS-RTLTAKDPDLGQNGWIRYSV-LDTELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQDEHLTVDTMSGTVCIQKTFDFEKQKSYQTTV-IATNA--NSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKP-----------EEPLLVVS---ASDMDSGTFGEVSYHIL----SESSSFSINPVTGEVFAQKPLAR---GRFHLVVSAKDGG 717 HSP 3 Score: 102.834 bits (255), Expect = 1.215e-21 Identity = 131/540 (24.26%), Postives = 236/540 (43.70%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEA-RSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSP-CL-LTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRV 2200
+ I + DVNDN P F V E K + + +A+D D + ++ Y + SF + +F L A + H ++ + Q ++ N N+ + V D + P+F+ S + + E+ ++ + + S +++ +Y + + FS+ ++ I ++ +LD + H + + T E+ ++ + + +ED ND PQ + I + E+ V +DKD + NG++ ++ P + T + T + D E + + + +D +S+ T+ + +LD NDN P+F +S Y V EN P T++ KV A D D NG+I Y + + F ID G + + +DRE+ H + I A D G P +S+ I+V DVNDN P CL +TP L+ A IG + D D G N V++ + ++ NG +Y+ + L+ + L V + D G+ R+ V +R+
Sbjct: 627 ISIRLKDVNDNWPIFYPNEYHLTVREGP-KPEEPLLVVSASDMD-SGTFGEVSYHILSESSSFSI---NPVTGEVFAQKPL-ARGRFHLVVSAKDGGGQSSE--NSANIHITVIDKDTKTPQFSRSKYEIRTTED-----ILPGIAIGSVGAMSKVKYSIY---SGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKK-NGEVRYSIISSHPGSSIEIDQ------FTGQLSTGSLLDYEATRNYKLRVKATDLGIPPR----SSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIVVPAGSPLSTA-IGTIVAMDPDKGLNGSVLY-RAQLQSSLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGVP-RKSVVCHVPVRI 1136 HSP 4 Score: 98.2117 bits (243), Expect = 3.087e-20 Identity = 161/658 (24.47%), Postives = 266/658 (40.43%), Query Frame = 2
Query: 584 VRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRT-KTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQIL--DFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPATI-GQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
++V +LD PQF K + + E + G+ + A ++ + +I Y L + L +D + + D E Q Y + A NA N + + + + + D NDN P F + + + V+E + + A+D DS + + + + FS+ + L R+ + V DG E + + + V D++ ++PQ ++ I E+ G+ IG V G M ++++S+ SG + D T K R + + ++ N A + S V I D NDNPP+F S + E+ + V A D D NG++ YS+ H S +ID TG ++ +D E +YKL + A D G P +S++ L I V DVNDN+P + V EN P TI G++ D D N +V+ T ++ + G +Y + +DRE + + D G+ R S+ I V+DVNDN P ++ I PA S + I ++A+D D N + Y L ++L F S G + L + L+ H + V V D G P
Sbjct: 524 LQVVADLLDTESKPPQFEKALWQVEIPEDT-PIGTCLVKVVANNSQCG-NSKRIRYSLQNQDE--HLTVDTMSG-TVCIQKTFDFEKQKSYQTTVIATNA--NSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSES---SSFSINPVTGEVFAQKPL---ARGRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSV-----------GAM--------SKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLL----NIQATLPSGESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPR-SSTASARISVLDVNDNPPSCLS------ITPIVVPAGSPLST---------AIGTIVAMDPDKGLNGSVLYRAQLQSSL----FVVKS-NGDVYLRRQLNASDERHQRLSVIVSDQGVP 1124 HSP 5 Score: 78.5666 bits (192), Expect = 3.203e-14 Identity = 173/697 (24.82%), Postives = 277/697 (39.74%), Query Frame = 2
Query: 503 LSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQF-SKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPP-------RFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQL-IQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDG-WNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHV--AENGPIGTVILKVNAYDLDDGLNGKIHYSL-EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDV--NDNSPCLLTPFEFSVRENLAPA-TIGQLQYEDSDIG--RNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSL----DKPLSHHYIGHYPIKVSVKDSGSP 2527
L D + Q HL LI+ L VR++V D NDN PQ + E ++E+S + G + A+D DI +N + + L E + + L L+ L + + IK+R + + E N+++ N NP F + + E P I +L P+ + Y + FSV G VI + LD E +RY + V T + + ++V V + ND P + P V EN G + V D D+ + + + F++ T I D E + ++ + +DG ++T N + + + D NDN P F + Y V A P G K+ A+DLD G + YSL + S+F++ +G + ++ V E Y + + A D+G ++SV +++ + + D F F V EN IG L E+S R D SK + D G L++ P+DRE + H +V + DN + ++ + + V+D NDN P TS A S+ S+ G I Q++A D D N +++Y IL N L I + N TG + L D L + I V +D G P
Sbjct: 1685 LPLDREASQEHL-LIIILTDGGSRNDSCTVRVTVADQNDNKPQLDASTPSELEIAESS-RVGDVLHRFRASDMDIG-QNGKFSFELLEDSSGSLDLVPETGDLVLRRLSSLQS-----WKIKLRVVDHGVPGLYVEKNLEIS----NRNPQTEAKAPLEFLKQTYLSTIDEGLPRGQFIAKL---QPELAGL----TYSIVEGNIDSAFSVDSEG-VIRTNLELDREILERYSLKVIGTGSGQQIGTRVDVRVNNLNDNVPSFPMSKPR--RVPENLRVGSYVATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNIDQ------FTGTIHLTAPLDFEVLPEHTLTIKATDGSFDTFTN--------LTIFVSDINDNAPTFSKPLYQTTVSPATFSP-GQPFAKIEAHDLD--ARGALTYSLGQGSSSIFRVAPESGALFMK--VLPPAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGLQIGNLSGEESREFHYRIQDPEASKIFSIDKF------GRLFVAGPIDREQRATHEFQVEI-DNEMMTSQKVQCKCHVIVLDENDNLPVF------------TSVAYYLSLKDSMAH--GQKIGQIMASDQDSGENGRVSYRILSGNDL--NIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHP 2317 HSP 6 Score: 73.1738 bits (178), Expect = 1.289e-12 Identity = 98/414 (23.67%), Postives = 180/414 (43.48%), Query Frame = 2
Query: 731 ENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSW----LDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS-----PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRT-----KTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGP-VDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL 1927
E+ + Y + + S +D+ + LF+ +D E + + ++ N Q + + V D NDN P F S + + +K++ I Q++A+D DS R + N+L + ++ + I ++ W LD + +++ V D + AR+ + + S P + + V+E++ G V+ ++ +++ + +G L +SL + K L D++T KT D E IS+ L SDG SA + L I V+ +D + P F +S Y + + P G + ++ A D D G++G + YS+ S +I+ TG+I +Q P V R ++ + A S + ++V L I DV + P LL
Sbjct: 2157 ESREFHYRIQDPEASKIFSIDKFGR--LFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDL-NIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDG------------LLYSLKEHQGK--LGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNGRSAVVPLK----IVVEPVD--EFAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSISDRQSTVKIEEHTGIIRLQKPLVSRRNLTIEQITVVAYSSPTKQSKTTVYLEIGPFDVQPSLPKLL 2547 HSP 7 Score: 70.8626 bits (172), Expect = 7.200e-12 Identity = 100/388 (25.77%), Postives = 160/388 (41.24%), Query Frame = 2
Query: 1412 FSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF----SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL--LTPFEFSVRENLAPATIGQL--------QYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
F L+S K + L D+ DRE + +++ DG + L S ++I+D NDN P F +S+Y A V+ N IG+ ++ V A D D G N +I Y ++ S F I S +GVIT + + + + A D GS L+SS + ITV +SP L + E + + +T+G + QY D+ + + V + L + LDRET H L+ L +G + + D+NDN P+ S I IS+ ++ G T L A D D N + Y + L +++ S + TG + + + + +V +D GSP L
Sbjct: 170 FKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCS----IEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFAI-SQSGVITTTASL--LPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENSTLGSIVARVSIAQQYRDTKLRLIGSSALCPQQTDQAHVYL-----LLLCGILDRETASEHHLKFLLEKDGQIIIEHPQ---LLTIGDINDNAPQW----------------HSSQIHISLNRTQGGSRT-LTAKDPDLGQNGWIRYSV-----LDTELVSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPAL 520 HSP 8 Score: 62.3882 bits (150), Expect = 2.483e-9 Identity = 132/619 (21.32%), Postives = 252/619 (40.71%), Query Frame = 2
Query: 302 IQENEPIDRMVGTI-ATDIEGLGINLEFHGSLIYKLSGPNCC-FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFN-DNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSV---IEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKT---------AFDREKSSQISVVLICSD-GWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLA-PA--TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPL 2101
+ EN + V T+ A D++ L F L+ SG F+IDQ + + + +D E + E + + G + NL I V D+NDN P FSK + VS A+ G A D D + Y L + S + ++ +L YL+ + A + + V + + + + P F + F V EN+ I L + R Y+ + E K+FS+ + G + ++ +D E+ ++ V + + + ++ V DE+ L SV + + ++ G IGQ++ +D+D + NG R+ + + SG + I+T + T + D ++ +++ D G A + +++++ ++ + P F Y HV E+ +GTV+ K+ A + N + YSL+ ID TG +T++ +D E + +++ D ++ V L I V+ V++ +P + T ++++ ++ PA ++GQ+Q D D G + V +S + + G + + KPL
Sbjct: 1935 VPENLRVGSYVATVGAKDVDNLAPLRYF---LVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLP---EHTLTIKATDGSFDTFTNL------------TIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLD---ARGALTYSLGQGSSSIFRVAPESGALFMKVL----PPAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGLQIGNLSGEES------REFHYRIQDPEASKIFSIDKFGR-LFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGE-NG-----------RVSYRILSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAV---GKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLKEHQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNG--RSAVVPLKIVVEPVDEFAP-VFTKSSYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSISDRQSTVKIEEHTGIIRLQKPL 2503 HSP 9 Score: 57.7658 bits (138), Expect = 6.819e-8 Identity = 81/310 (26.13%), Postives = 132/310 (42.58%), Query Frame = 2
Query: 1370 KMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFA-HVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-LFQIDSTTGVITVQGPVDRELK--EHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEF-------SVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVM-ITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPR--LINPRGLRE 2254
+++ T E R F ++ K T + DRE S + +++I +DG + + S T+ V + D NDN P+ S +AE+ +G V+ + A D+D G NGK + L D S + TG + + R L + +K+ + VD G L V N+ + + N + P EF ++ E L I +LQ E A + +S N D+ + G + LDRE +R+ L+V G +Q V +RV ++NDN P + PR + E
Sbjct: 1652 RILATGMTEESRFRFQGNAPKFSINSTTGSISVLPLDREASQEHLLIIILTDGGSRN------DSCTVRVTVADQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSLDLVPETGDLVL-----RRLSSLQSWKIKLRVVDHGVPGLY--VEKNLEISNRNPQTEA-KAPLEFLKQTYLSTIDEGLPRGQFIAKLQPE------LAGLTYSIVEGNIDSAFSVDSEGVIRTNLELDREILERYSLKVI----GTGSGQQIGTRVDVRVNNLNDNVPSFPMSKPRRVPE 1937
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 113.235 bits (282), Expect = 8.062e-25 Identity = 152/596 (25.50%), Postives = 244/596 (40.94%), Query Frame = 2
Query: 596 ISVLDVNDNIPQFS----KQRIERHVSEASH---KAGSHIFLETATDTDIAPENAQIEYGL-----AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWN-------AQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGK-GLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQIS----VVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAEN-GPI---GTVILKVNAYDLDDGL--NGKIHYSLEHDF-----SLFQIDSTTGVITVQGPVDREL--KEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPATIGQLQYEDSDIGRNA-DVVFSKTWPND-DTVMITVN--------GTLYITKPLDRE---TKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL 2230
+ V DVND +PQF+ I+ ++ H G I A DTD ++ Y + E K F++ + +F D E Y++ + A + + + + V + ++D NDN P F + VKE+ + + A+D D S LR+ L R F V + I + LD+E +Y + + +DG + A + + + +ED ND +PQ Q V+E V+ V TD D + + +++ E F + GK + I A DR+ + + VV D N L + V + D NDN P F + + F ++ EN PI G + V A D DD N I Y + + S+F+ID TG I +DRE+ + + + + A D G + I V D+NDN+P T +E SV E AP + + D A D VF+ + D +T + G L + +PLD E +D L +R+ D GR + V + ++D ND+ P +
Sbjct: 1199 VEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRI---DELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGG--RIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDGRHNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRI--GK----YSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNG-----LVGYADVQVNVRDINDNSPIFPE-RLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEET-APIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSD----GRHDAEAAVHVALVDRNDHAPHI 1772 HSP 2 Score: 102.834 bits (255), Expect = 1.236e-21 Identity = 141/546 (25.82%), Postives = 229/546 (41.94%), Query Frame = 2
Query: 857 LIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNG----TVILISSWLDYERHQRYKVPVFVTD-----GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKD-DSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAE--NGPIGT---VILKVNAYDLDDGLNGKIHYSLEHDFS----LFQIDSTTGVITVQGPV--DRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVR--ENLAPATIGQLQYEDSDIGRNADVVFS--------KTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHI 2389
L K++ +DN++ + +++ + +DD NDN P F L++ V+E+ P I ++ A D D+ R Y N+ FS+ NG V L + L+ ERH Y+ V D L + + ++ + L + V E++ G + Q+ D D D T M +T+ FS+ L + + + E ++V++ + TS T+ + I D N+N P+F ++ +A+ G T I+KV A D D NG I YSL + S F ID TGV+T V DRE + + + A D G PL ++ V D+NDNSP P +E SV E + + I + D+D NA++ +S + ND VN G + + KP+ +T+ + V DNG+ QSS +V + V+D P+ TSP I++ VI + AV D+ N+ + Y +
Sbjct: 610 LHKLKVTAREDNRE-SHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRI-TYSVDNHN----FSINSNGEISAKVRLDADQLN-ERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAF-DNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQ-KFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKW-----------QTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKL 1135 HSP 3 Score: 99.7525 bits (247), Expect = 9.546e-21 Identity = 185/770 (24.03%), Postives = 316/770 (41.04%), Query Frame = 2
Query: 389 SLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL------AEHHKS----FQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSS---LFSVLVKENTPARSMIFQLIA---NDPDSTSVLRFDLYQT------ANNELRKLFSVLQNG---TVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS--PQL---IQNPSVIEVM-------ENSGKGLVIGQVIVTDKDDSQ--TNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTS---ANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLA--PATIGQLQYEDSDIG-RNADVVFSKTWPNDDTV--MITVNGTLYITKPLDRETK---DRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQ-IFSFNSTTGYL----SLDKPLSHHYIGHYPIKVSVKDSGSP 2527
SL Y S F ID+++ VLT + ++ + RE + ++ +G LI + + V+D+NDN PQF + E VS G+ + A D D A NA+I Y L E H++ F+L +R + L+ + + Q I N + V L V D P++ +S + V EN +I + A D ++ V+ + L + A ++ R+ F+ +NG ++I LDYE+ Y + + TD S +VE + PQ + ++ E M + +GK +V + I TD D Q + +++ E E + F + LT +I FDREK + + SD ++ AN + + + I D NDN P F + +Y V E+ G ++ + A+DLD N + H + F + + +G I V+ P+D E + Y L + A D N++ + I ++DVNDN+P + +V E P + + D+D +++ +V+ D V + +GT+ + K LDR+ V+ D+ NG +V + V D+NDN P + R I++ P S + Q+ + DD N + Y I+ + + +F + TG + SLD+ +S + I+V D G P
Sbjct: 908 SLYYTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLI----------GFCQFSVEVVDINDNSPQFERPSYETSVSRF-EAVGTSVITVFAFDNDAA-HNAEITYSLEIDTTAGEEHQNDLDFFELV--NRRSGEITLIKPIPMKTQKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVI-YKLTASGGPGNKAESKFRQ-FNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATDMTSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETK-HFRIDE------LTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDGRH---NATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNG-LVGYADVQVNVRDINDNSP-IFPERLFGYIEENREPIHSDGVYFMDVQARDF--------DDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSER--EFIIEVRANDRGVP 1639 HSP 4 Score: 83.1889 bits (204), Expect = 1.317e-15 Identity = 64/230 (27.83%), Postives = 106/230 (46.09%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIH-YSLEHDFSLFQI-------DSTTGVITVQGPVDRE---LKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKP 2224
+ +++ D NDN P F +++Y V E PIG ++ +A+D D+ + Y L + F + S+ GV+ V+ P+D E ++ + L I D ++ +++ + D ND++P + E VRE++ T IG+ D D G A ++ I +GTL + LDRE + L + DN N RQ V + + DVNDN P
Sbjct: 1647 VTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRH---DAEAAVHVALVDRNDHAPHIHGATEHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQDGTLRVAHTLDREDIAVYNLIIEAYDNSNNIGRQM---VAVYLQDVNDNGP 1870 HSP 5 Score: 78.5666 bits (192), Expect = 3.251e-14 Identity = 168/772 (21.76%), Postives = 311/772 (40.28%), Query Frame = 2
Query: 386 GSLIYKLSG-----PNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELN----VDLYVDDFNDNPPRF-NSSLFSVLVKENTPARSMIFQLIANDPDSTSV-LRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVT-----DG---LYEARSXXXXXXXXXXXXS--------PQLIQNPSVIEVMENSGKG--LVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLE----------HDFSLFQ-IDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIP--LNSSVGLNITVDDVNDNSPCLLTPFE----FSVRENLA-PATIGQLQYEDSDIGRNADVVFSKT---WPNDDT------VMITVNGTLY----ITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVD-DDDATNTKLTYHIL-LPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKD 2515
G + Y L G F ID + ++ + + +D + + + ++ + + E V+L I + DVNDN+P F++ V E I TA D D +N++I Y + H+ F + + + + L D D N+ H++ + A+D+ + L+ + + ++ ND F +S ++ V E+ + + Q+ A D D V F + + LFS+ ++ ++ + + + P+ +T DG +Y +++ E P + + ++ME + K I +V TD DDS NG ++ T+ + + +LT FDRE + V + +D + L +V+++D NDN P+F + Y V+ +GT ++ V A+D D N +I YSLE +D F+ ++ +G IT+ P+ + ++ + ++ A D+G IP L SS + + V D +P T + +V EN+ I + + S RN+DV++ T P + NG + I + LD E + + L + D + R S+ + V DVND P+ ID+ +P + ++ G I + A+D D D ++ Y I+ N ++ F + TG + ++ I Y + V D
Sbjct: 567 GPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDL------------TIRIDDVNDNVPTFTRPLYTAQVRE-DIPLNQTILKVTAVDKDTG-DNSRITYSVDNHN--FSINSNGEISAKVRL--DADQLNERHFVYRFNV-TARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATD-DDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLTPS--PHVVFDRETRPREDVTVKATD----RGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQK-FIFNVIADDNG-IPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATD--MTSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNE------HLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASD 1302 HSP 6 Score: 74.7146 bits (182), Expect = 4.014e-13 Identity = 97/367 (26.43%), Postives = 155/367 (42.23%), Query Frame = 2
Query: 1559 SSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLE-HDFSLFQIDSTTGVITVQGPVDR-ELKEH---YKLHIHAVDSGS-IPLNSSVGLNITVDDVNDNSPCLLTPFEFS--VRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLR-----------DNGLNGR--RQSSGEVC--------------IRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYP-----IKVSVKDSGSPPLI 2536
S + ++I D NDN P F + Y A V E+ P+ ILKV A D D G N +I YS++ H+FS+ ++ G I+ + +D +L E Y+ ++ A D G + L+SS ++I ++ ND S L +++ V E+ T + Q+Q D+D +V +S + NG T+ ++ + D H V+LR +N +N Q G C I + DVN+NKP E D + I Y++ I ++ A DDD + N + Y + + + F + TG L+ P H + V D G PLI
Sbjct: 624 SHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHNFSI----NSNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDAD---RDEVTYS---------FMDKNGRS--TQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKP---------EFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKAFVIDRQTGVLT---PSPHVVFDRETRPREDVTVKATDRGDRPLI 960 HSP 7 Score: 71.2478 bits (173), Expect = 4.592e-12 Identity = 96/347 (27.67%), Postives = 152/347 (43.80%), Query Frame = 2
Query: 1556 TSSFTINVQILDF--NDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDL---DDGLN-GKIHYSLEHDF-----SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLA-PATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDR-ETKDRHCL---RVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQ---IFSFNSTTGYLSLDKPLSHHYIGHY--PIKVS--VKDSGS 2524
T+S V IL+ ++ PP+F + +Y V+E+ + ++ V A +DG + G I YSLE D F+ID +TG+I + +D + KLH V + S V L I +DDVNDN P P + VRE++ TI ++ D D G N+ + +S ++ I NG + LD + +RH + V RD+G SS + IR + ND + A SQ + + G T +I + DA ++TY + N +Q +FS + TG + L +S + PI ++ V+D GS
Sbjct: 509 TTSQLSEVAILEILADERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSV---DNHNFSINSNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTND--------------ESAVFLPTSQYTAFVAEDAQGG--TPVIQIQARDADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGS 836 HSP 8 Score: 70.0922 bits (170), Expect = 1.142e-11 Identity = 140/572 (24.48%), Postives = 231/572 (40.38%), Query Frame = 2
Query: 371 NLEFHGSLIYKL---SGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQT---HYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARS---MIFQLIANDPDSTSVLRFDL-YQTANNEL---RKLFSVLQNGTVILISSWLDYE--RHQRYKVPVFVTDGLYEAR---SXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDI-RTKTAFDREKSSQ---ISVVLICSDG-WNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVG---LNITVDDVNDNSPCLLT-PFEFSVRENLAPATIGQLQYEDSD 2002
+L+ H +L Y L G F + S + + + +D E+ S Q HL LI S+ + A V I + DVNDN PQF +Q+ V E +F ATD D ++++I Y L E + ++ + + L+ LD + + ++A + N +V + V D NDN P F LF + + P S + A D D + ++ Y N+L +F + QN I LD E + + + V D +R + + + V D ND +P + V E + G + D D+ + + ++ +E F +++ K+ K + + R K D E +Q + + SDG + A +H V ++D ND+ P + V E+ P GT I + A D D G + + + D F ID G + V +DRE Y L I A D+ ++++G + + + DVNDN P T P REN +G + +D
Sbjct: 1361 DLDKHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEA------------SDQYHLVLIA---SDGRHNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRL-EGQGADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDN--VFTYQLSEESDYFYVTTDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAAVH--------VALVDRNDHAPHIHGATEH-RVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQ-DGTLRVAHTLDREDIAVYNLIIEAYDN-----SNNIGRQMVAVYLQDVNDNGPEPYTVPRPCIFRENTPVNQLGTCEIRATD 1899
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0078045) HSP 1 Score: 186.037 bits (471), Expect = 5.066e-47 Identity = 204/785 (25.99%), Postives = 343/785 (43.69%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFH---GSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIE---RHVSEASHKAGSH-IFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLND-LDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDST--SVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRT-----KTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-------------EHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPATI-GQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQ-IFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMF 2551
+ ENEP+ R + ++ G+N + G L+ F + S + IA +D E + E V L +++ + DVNDN P F + + R +AS +A S I ATD D Q+ Y + +++ +D+ + D L Q +++ I A + + + + V L + D PP F + ++ VKE+ P +++ +IA D S +R+ +Y + + FS+ N I I+ LD+E + + + T G +Y + + + VED ND +P+ + I V E++ G + DKD S ++G++ +SL K + D R+ D E S + ++++ +DG S L+++ TI V + D NDNPP F + +Y +V+E+ I I++VNA DLD G N +I Y + D S F I +G I ++ P+DRE ++ Y+L + A D+G+ ++ + + V D NDN P + +EF + ENL ++ G + D D+G NA + +S N + V G + +PLDRE ++ + L V RD G R + V I V DVNDN P + +P+ +S+ Q PG + ++ AVD D N +TY I+ +FS + T+G + L H Y + V+ D G+PP +M
Sbjct: 620 VAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLT----EFEVRSASGEICIAGELDFER--------------RSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYG-NFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIY---SGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVY-GHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKD-SGSSGQVT-----------YSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPS----LSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQG-TPVRSARVPVRIHVSDVNDNAPEIADPQ-------------EDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRML 1351 HSP 2 Score: 162.155 bits (409), Expect = 1.333e-39 Identity = 213/783 (27.20%), Postives = 334/783 (42.66%), Query Frame = 2
Query: 419 CCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDL----------DAENQTHYLIKIRAWNAQDN---KQWNELNVDLYVDDFNDNPPRF---NSS---LFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWL----DYERHQRYKVPVFVTD-GLYEARSXXXXX---XXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLIC---------------------SDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQ-SQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHD--FSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNIT--VDDVNDNSPCL-LTPFEFSVRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGT---LYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKP 2575
F ID+ S L +A+ +D RE+ S+ + + + SN + + V+I V DVNDN P++ + I+ VSEA+ G+ I TATD D N ++Y L + QL Q++ LF ++ L D E YL+ ++A + N + + V L + D ND+ P F NSS S+ + + T ++ ++A D DS + T N + Q G + L+ S D E+ R+ + + D G E + L V+ ++ P+ +Q ++EN G + QV H L + + +G + D I T+ FDRE SQ S VL SD ++N TI + + D NDN P+FR S Y V EN G VI V A DLD+G N + YS+ + F IDS++G ++ + P+DRE Y L I A D G P + NIT V+D NDN+P L+ + SV+E+ AP ++ Q+ D+D+G NA +V+S N+ ++G + LDRE + + V D G R ++ V I V+D+NDN+P + ++ PA Q PG + ++ A+D D N ++ Y + N+ S F N +TG LS + L+ ++V +D G+PP + L I P
Sbjct: 1424 AAFDIDRHSGNLVVARLLD-------REVQSEF---RLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEAT-PVGTIIHNFTATDADTG-TNGDLQYRLIRYFP--QLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAK------------SLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRE--SQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG-VIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSAR-PLDREQHSRYTLQIQASDRGQ-PKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQED-APLGTSVVQISAVDADLGVNARLVYS--LANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQV-----PALIQ---------PGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAP 2158 HSP 3 Score: 160.614 bits (405), Expect = 4.091e-39 Identity = 163/581 (28.06%), Postives = 270/581 (46.47%), Query Frame = 2
Query: 551 NLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIA---PENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVME---NSGKGLVI-GQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD--------IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFE--FSVRENLAPAT-IGQLQYEDSDIGRNADVVFS--KTWPNDDTVMITVNGTLYITKP---LDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKP 2224
NL SN + V +S++D P F K R +V E + G+ + A D+A P I G + + S + R + LD E ++ L+ I+A + + V++ V+D NDN P F +S+ + V E+ + ++ A+D DS S + Y + LF++ +++S LDYE QR+ + V TDG + S ++ D D + NP V E E N + I Q+I + D T + + ++ +S + + + I + DRE + + ++ +D +A+ + + V++LD NDN PKF++S+Y + EN G+V+ V A DLD G N I YSL S FQ+ TG I+ + P+DREL+E Y L + A D G+ ++ V + I V DVNDN+P + P E SVRE P T + +++ D D G+NA + +S K +D + +++ T + + LD E + + L V D G N R++ + + V+D+NDN+P
Sbjct: 804 NLRSNADAV----VFLSIIDAMQRPPIFEKARYNYYVKEDIPR-GTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIR-----IAKPLDHEAKSQVLLNIQATLGEP-PVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQV-TYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVN----DNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAH----AKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGG-NPPRETVRMLRVEVLDLNDNRP 1363 HSP 4 Score: 159.844 bits (403), Expect = 5.945e-39 Identity = 182/682 (26.69%), Postives = 305/682 (44.72%), Query Frame = 2
Query: 584 VRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHH--KSFQLCLDQQRQPYLFL----LNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD---GLYEARSXXXXXXXXXXXXSPQL----IQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILT------YDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL----EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPF-EFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITV---NGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPR----GLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKP--LSHHYIGHYPIKVSVKDSG 2521
+RV ++V D NDN P F + + E + + L A D D+ P N Q Y + + +F+L ++R L+L LD E Y + I A + + V++ + D NDN P FN S + V EN + + Q+ A+D D+ ++ + + + +++ ++F + I I+ LD+E + +++ V D E + + + V D ND P + + + + ++ E++ G + ++ V D D +T + +L+ G LT Y + DRE S ++ ++ +D L +S +I ++I D NDNPP+F Q Y A+V E GT +L+V A+D D+GLN + YSL E FQID TG+IT + +D E + +L + A D G PL+S+ + +T+ DVNDN P F SV EN I ++ D D G NA V ++ V +G + I LD E + + V D G ++ + +++ DVNDN+P + PR LRE A+S A+S I ++A D D +++Y I+ N + IF + +TG + + +P LS + + +S D G
Sbjct: 158 IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLL-PARDLDLEPYNTQ-RYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDK-EQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDS-----------KTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPP----LHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATD---RGGLSTTAMIKMQLTDVNDNRP-VFYPREYKVSLRESPKASSQASSTP------------IVAVVATDPDYGNFGQVSYRIVAGNE--AGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGG 803 HSP 5 Score: 148.673 bits (374), Expect = 1.822e-35 Identity = 172/694 (24.78%), Postives = 301/694 (43.37%), Query Frame = 2
Query: 578 AVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQL----CLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVL-VKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS---PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKI-LTYDIRTKTA-------FDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-----------EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGS---IPLNSSVGLNITVDDVNDNSPCLLTPFEFSVREN---LAPAT-----IGQLQYEDSDIGRNADVVFSKTWPNDDT--VMITVNGTLYITKPLDRETKD-----RHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDS 2518
A RV + VLD NDN P+F K + E + E + + GS + + TA+D D+ ENA I Y L + SFQ+ R+P LD E + Y + + A + + + V ++V D NDN P V+ V+E P + + ++ A D D + + + + + +++ LFS+ VI LD+E Y++ V +DG R + +L + D + P + V V E++ G V+G + ++ + E + R+ ++L+ I +DI + DRE S+ + + D T++N +S+ T+ +++ D NDN P++ Q V+E P+GT+I A D D G NG + Y L E SLF++DS TG +++Q P+D E + Y L + A+D S L +SV + + + D ND++P ++P + ++ AT + + D D G N + + T N + + + G + + K L T+D R L + +D+G ++SS + + V ++N PR + A +I G + Q+ A A N L+Y I P + + +F + G ++ Y + V V+D+
Sbjct: 1135 AKTRVIVRVLDANDNDPKFQKSKYEFRIEE-NLRRGSVVGVVTASDLDLG-ENAAIRYSLLPINSSFQVHPVTGEISTREP-------LDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSV--EESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALD--TTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQ--------------AVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEI--PAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDA 1799 HSP 6 Score: 138.658 bits (348), Expect = 1.850e-32 Identity = 170/679 (25.04%), Postives = 285/679 (41.97%), Query Frame = 2
Query: 572 LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHK-SFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFN----SSLFSVLVKENTPARSMIFQLIANDPDS-TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG----LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF---SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQ--------LQYEDSDIGRNADVVFSKTWPNDDTV--MITVNGTLYITKP--LDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
L + V I++ DVNDN P F++ R V E + G+ + A+DTD A EN +EY + Q+ R +++ LD E + + + + A + + V + V D NDN P N S S + E+ + ++ +DPDS T ++ + L + + ++++ LD E Y + V TD L+ ++S+ + + ++ P+ Q+ VME + G + QV+ D+D+ + ET E ++ + I T R+ + E Q++VV DG L+S+ T+ V I D NDN P F QS Y VAEN P+G ILKV+A D D G+N ++Y++ F + F++ S +G I + G +D E + Y+ + A D G + + + + +T DVNDN P P E+ V +P Q + D D G V + N+ + + G +++ +P L T+ H L + D G N R + V + +ID P R + + G V+ +IA D A + + Y I + P FS + +G + + KPL H + + G PP+
Sbjct: 266 LRGFMTVNITIQDVNDNQPIFNQSRYFATVPENA-TVGTSVLQVYASDTD-ADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDN-PPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITT---RSHIDCETEPVPQLTVV--ARDGGVPP----LSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLT--DVNDNRPVFY-PREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGG-NLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDI--------------PRGTVVGSVIAASGDVAHRSPVRYSIYSGD--PDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQAT-LGEPPV 911 HSP 7 Score: 137.887 bits (346), Expect = 3.612e-32 Identity = 170/671 (25.34%), Postives = 282/671 (42.03%), Query Frame = 2
Query: 332 VGTIATDIEGLGINLEFHGSLIYKL-----------SGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNL--WSNV--QLLAVVRVRISVLDVNDNIPQF------SKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDL-----DAENQTHYLIKIRAWN-AQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG----------LYEARSXXXXXXXXXXXX----------------SPQLIQNPSV-IEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSD-GWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSS-VGLNITVDDVNDNSPCL-LTPFEFSVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDD-TVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNG 2155
VGTI + + +G L Y+L F +D + L++ +D E++ Q +L ++ L SNV +L V VR+ +LD ND+ P F + +S+A+ + G + A D D + +N Q+ Y + + + ++ Q + L+ L D E + + I A + Q + + LN+ L V ++NPPRF +++ + EN P+ S + Q+ A Y+ LF V +I D E Y +PV+V D + + RS + SP+ + V ENS G VI V+ +D D+ N +I +FS+ S + + DRE+ S+ ++ + SD G S H I + + D NDN P+F+ S+Y V E+ P+GT +++++A D D G+N ++ YSL ++ F ID +G+IT G +DREL+ Y + A D G + S+ V + I V D+NDN P P+ V + P T+ ++Q D+D+G NA++V+S N + +N G L ++ L E+ L V RD G
Sbjct: 1500 VGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAV-------------QEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDAT-RIGEVVAHIVAVDED-SGDNGQLTYEITGGNGEGRFRINSQTG-IIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLS-YEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG-VIHTVVASDLDEG-PNADLIYSITGGNLGNKFSIDSSSGEL-------SARPLDREQHSRYTLQIQASDRGQPKSRQGHCN----ITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKG 2140 HSP 8 Score: 116.316 bits (290), Expect = 1.304e-25 Identity = 122/409 (29.83%), Postives = 178/409 (43.52%), Query Frame = 2
Query: 1448 TYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-----EHDFSLFQIDSTTGVI----TVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFS-VRENLAPATIG----QLQYEDSDIGRNADVVFS-KTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSL-DKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFIT---NKPAKYDDKLQSNN 2608
T +IRTK DRE + S+V I G N + V + D NDN P F Q+ EN P + A DLD Y++ F L GV+ + G +DRE Y L I A+D G+ PL + +NIT+ DVNDN P F+ V EN AT+G Q+ D+D N V ++ +D M ++ G +YI K LD ETK+ H L V +D+G +++ V IRV DVNDN+P + + + D SP S+S PG + + I+V D D+ ++ L + + YL + PL + +Y + V D G+PPL K +L IT + P +++ L N
Sbjct: 129 TGEIRTKVKLDRETRASYSLVAIPLSGRN----------IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPEN---ATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHG-EQPLETTAFVSIRVTDVNDNQPTI----NVIFLSDDASPKISES------AQPGEFVAR-ISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHAN 512 HSP 9 Score: 115.931 bits (289), Expect = 1.624e-25 Identity = 161/580 (27.76%), Postives = 265/580 (45.69%), Query Frame = 2
Query: 572 LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDL--YQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQN---------PSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDI-RTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLN------ITVDDVNDNSPCL--LTPFEFSVRENLAPA--TIGQLQYEDSDIGR--NADVVFSKTWPNDDTVMIT--VNGTLYITKPLDRETKDR-HCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL 2230
L + + I + D NDN P+FS+++ VSE ++K G+ + A D+D A NA++ Y + + + ++ + LD E + Y +KI A + + + + + D NDN P F + V V E T ++I + AND D+ L + L T + E +F++ + +++ LDYE Q Y++ V +D +EAR+VL V V DEND +P + P++ E+ E+ + V TD D N K+I E + S+G +++ ++ R + A S V +I D + L SS + VQ D +F Q+QY A ++E P+G+V+L++ LD L I + E F L Q + I + P+DRE + YKL + PL SS+ + IT+ D NDN P +E + E LAP +I QLQ D+D N++VV+ T ND+ + V G L++ LD ++ + + L +R D+ S + + D NDN+P+
Sbjct: 2302 LASYAELVIELEDENDNSPKFSQKQFVATVSEGNNK-GTFVAQVHAFDSD-AGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNG----VVSVNMSRLQPAV--SSSGDYFVRIIAKDAGKPA----LKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSL-AIIAGNEESAFELLQ----SKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISE-LAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKF 2862 HSP 10 Score: 113.235 bits (282), Expect = 9.661e-25 Identity = 174/731 (23.80%), Postives = 302/731 (41.31%), Query Frame = 2
Query: 422 CFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQ----FSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN-DLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS---PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIG-----TVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGP--VDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPATI-GQLQYEDSDIGRNADVVFS--KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVR--LRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSP--GYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
F ID ++ + I K +D E+ +EL + H E ++ A V +R++ DVNDN P F +SE S + G + + D D E A + L F L + YL +++ LD E ++Y + + A + ++ L + D NDNPP F L+ V E + + Q++A+D D S L + L +T + F + +I S +D E ++ V DG S ++ +D + P Q+ + V EN G I +V +D D E + EF + S + + ++ F+R S + V+ G +T+A I +Q+ D NDN P F +Y + E+ T I+ V A D D G G++ Y + ++ +F+ID +TG I V P + + + L+I A D G++ N+ + +++ D P + + V+E++ T+ G + D+ + V +S P+ + T +G + I KPLD E K + L ++ L + + G Q V I V DVNDN P + + ISV +S G + A D D ++ ++TY ++ + +F+ ++ +G+L L + L + + + V+ D G P L
Sbjct: 335 MFRIDPRTGAIYINKALDFET----KELHELVVVAKDHGE------QPLETTAFVSIRVT--DVNDNQPTINVIFLSDDASPKISE-SAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTT-RDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHA-QWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELD----FERRSSYEFPVLATDRGGLSTTA--------MIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQ----VNIEVEDVNDNAPEF----------------EASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESG--KGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSL 1016 HSP 11 Score: 91.2781 bits (225), Expect = 4.631e-18 Identity = 138/628 (21.97%), Postives = 258/628 (41.08%), Query Frame = 2
Query: 371 NLEFHGSLIYKLSGPNCC-------FSIDQKSSVLTIAKNIDLESICINRELSSDC-SSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQR------IERHVSEASHKAGSHIFLET--ATDTDIAPENAQIEY-------GLAEHHKSFQLCLDQQR-QPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSV----------IEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAF-------DREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL------EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLT-PFEFSVRENLA-PA--TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPL 2101
+++ + +L Y+L + F++D+ S L + + +D E + +E D +S H + V+ VR++ D NDN P F Q+ I +SE S L T ATD D N+++ Y G + H + + ++ R QP + D Y ++I A +A + + + +D +F + + + E P S++ QL + D + L A NE F +LQ+ ++L+ LD ER+ YK+ + ++ + L N + E+ E + I Q+ D D T + + ++SG ++ + T D+ T F D S ++ C ++ L S +++ D NDN PKF ++Y +AEN P+G+ + + +A DLD G G+++YS+ E + +F++DS +G++T D E ++ Y + + A D G +SV + + ++ ++ +P + F + +A P +GQ+ DSD G + VV+ + P+ + +G + I + L
Sbjct: 2453 DVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYE---LQQEYELDVIASDAAH-----------EARTVLTVRVN--DENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGD--------YFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQS------LAIIAGNE-ESAFELLQSKAIVLVKP-LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVV----------YDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRAC----DSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGG--KKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSHFKVNRSSGAVLIKRKL 3032 HSP 12 Score: 90.1225 bits (222), Expect = 1.068e-17 Identity = 106/423 (25.06%), Postives = 179/423 (42.32%), Query Frame = 2
Query: 1424 SGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLA-PATIGQLQYEDSDIGRNADVVFSKTWP-------NDDTVMIT---------VNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLI--NPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYI---GHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGGS 2617
S ++++ LT + A + ++I VVL+ T+ L S + +++ D NDN PKF Q Q+ A V+E GT + +V+A+D D G N ++ Y + HD + + +G++ +DRE+++ YKL I A D G + + + + + DVNDN P +V E A I + D D T+P + TV I +G L + + LD E + + L V D R + +RV D NDN P + P I A S S+S+S+ + + + A D D N +I+ P + FS + + G +S++ + G Y +++ KD+G P L + ++Q+N+ GS
Sbjct: 2266 STRSQRALT---SSSFALTNSQPNEIRVVLVA----RTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVD-----------TYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTV----LTVRVNDENDNAPVFLAQQPPAYFAILPAIS-EISESLSVD------FDLLTVNATDADSEGNNSKVIYIIEPA---QEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLL-------------RVQANDNGS 2643 HSP 13 Score: 74.3294 bits (181), Expect = 7.289e-13 Identity = 175/685 (25.55%), Postives = 294/685 (42.92%), Query Frame = 2
Query: 536 LELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL-AEHHKSFQ----LCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNS----SLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNE--------LRKLFSV-LQNGTVILISSWLD--YERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSS--QISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKF-RQSQYFAHVAENGPIGTVILKVNAYDLD--DGLNGKIHYSLE--HDFSLFQIDSTTGVITVQGPVDREL-KEHYKLHIHAVDSG-SIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVREN-LAPATIGQLQYEDSDIGRNADVVFS-KTWPNDDTV--MITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRV-IDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPL 2467
L++I Q+ +R+ ++DVNDN P F + VSEA+ + G+ I +A D D P + Y L AE + LD+ L L LD E Q Y + + A +A + + + V+D NDN P F + + F++L PA S I + ++ D D +V D NN ++ FSV NG V + S L Y V + D ++ ++L V D Q +QN ++ E + G V+ Q+ +D + +I +E + F L K ++ DRE++ ++ +VL G ++++ +S ++ + ILD NDN P F R ++Y A ++E P+ I ++ A D D + N ++ Y + +D +F ID TGV+ V +D + + Y+L I A DS PL S + + D NDN P LT + + EN +++ + D D G + +S P+D++ M V+ G + D E + R+ + + D G G++ S V +RV I+ D R R + PAA V GYV+ Q+ A D D + ++ Y + P++ F N ++G + + + L
Sbjct: 2396 LKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVT-VSEAT-ELGAVITSISANDVDTYP---ALTYRLGAESTVDIENMSIFALDRYSG-KLVLKRRLDYELQQEYELDVIASDAAHEARTV---LTVRVNDENDNAPVFLAQQPPAYFAIL-----PAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQL---GQDALDQSLAIIAGNEESA----FELLQSKAIVLVK-------PLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMG--GKKAS---VAVRVEIESRDEFTPQFTERTYRFV----LPAA-------VALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSH----FKVNRSSGAVLIKRKL 3032
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Match: ds (gene:FBgn0284247 transcript:FBtr0343249) HSP 1 Score: 186.037 bits (471), Expect = 5.066e-47 Identity = 204/785 (25.99%), Postives = 343/785 (43.69%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFH---GSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIE---RHVSEASHKAGSH-IFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLND-LDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDST--SVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRT-----KTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-------------EHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPATI-GQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQ-IFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMF 2551
+ ENEP+ R + ++ G+N + G L+ F + S + IA +D E + E V L +++ + DVNDN P F + + R +AS +A S I ATD D Q+ Y + +++ +D+ + D L Q +++ I A + + + + V L + D PP F + ++ VKE+ P +++ +IA D S +R+ +Y + + FS+ N I I+ LD+E + + + T G +Y + + + VED ND +P+ + I V E++ G + DKD S ++G++ +SL K + D R+ D E S + ++++ +DG S L+++ TI V + D NDNPP F + +Y +V+E+ I I++VNA DLD G N +I Y + D S F I +G I ++ P+DRE ++ Y+L + A D+G+ ++ + + V D NDN P + +EF + ENL ++ G + D D+G NA + +S N + V G + +PLDRE ++ + L V RD G R + V I V DVNDN P + +P+ +S+ Q PG + ++ AVD D N +TY I+ +FS + T+G + L H Y + V+ D G+PP +M
Sbjct: 620 VAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLT----EFEVRSASGEICIAGELDFER--------------RSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYG-NFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIY---SGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVY-GHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKD-SGSSGQVT-----------YSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPS----LSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQG-TPVRSARVPVRIHVSDVNDNAPEIADPQ-------------EDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRML 1351 HSP 2 Score: 162.155 bits (409), Expect = 1.333e-39 Identity = 213/783 (27.20%), Postives = 334/783 (42.66%), Query Frame = 2
Query: 419 CCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDL----------DAENQTHYLIKIRAWNAQDN---KQWNELNVDLYVDDFNDNPPRF---NSS---LFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWL----DYERHQRYKVPVFVTD-GLYEARSXXXXX---XXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLIC---------------------SDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQ-SQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHD--FSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNIT--VDDVNDNSPCL-LTPFEFSVRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGT---LYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKP 2575
F ID+ S L +A+ +D RE+ S+ + + + SN + + V+I V DVNDN P++ + I+ VSEA+ G+ I TATD D N ++Y L + QL Q++ LF ++ L D E YL+ ++A + N + + V L + D ND+ P F NSS S+ + + T ++ ++A D DS + T N + Q G + L+ S D E+ R+ + + D G E + L V+ ++ P+ +Q ++EN G + QV H L + + +G + D I T+ FDRE SQ S VL SD ++N TI + + D NDN P+FR S Y V EN G VI V A DLD+G N + YS+ + F IDS++G ++ + P+DRE Y L I A D G P + NIT V+D NDN+P L+ + SV+E+ AP ++ Q+ D+D+G NA +V+S N+ ++G + LDRE + + V D G R ++ V I V+D+NDN+P + ++ PA Q PG + ++ A+D D N ++ Y + N+ S F N +TG LS + L+ ++V +D G+PP + L I P
Sbjct: 1424 AAFDIDRHSGNLVVARLLD-------REVQSEF---RLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEAT-PVGTIIHNFTATDADTG-TNGDLQYRLIRYFP--QLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAK------------SLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRE--SQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG-VIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSAR-PLDREQHSRYTLQIQASDRGQ-PKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQED-APLGTSVVQISAVDADLGVNARLVYS--LANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQV-----PALIQ---------PGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAP 2158 HSP 3 Score: 160.614 bits (405), Expect = 4.091e-39 Identity = 163/581 (28.06%), Postives = 270/581 (46.47%), Query Frame = 2
Query: 551 NLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIA---PENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVME---NSGKGLVI-GQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD--------IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFE--FSVRENLAPAT-IGQLQYEDSDIGRNADVVFS--KTWPNDDTVMITVNGTLYITKP---LDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKP 2224
NL SN + V +S++D P F K R +V E + G+ + A D+A P I G + + S + R + LD E ++ L+ I+A + + V++ V+D NDN P F +S+ + V E+ + ++ A+D DS S + Y + LF++ +++S LDYE QR+ + V TDG + S ++ D D + NP V E E N + I Q+I + D T + + ++ +S + + + I + DRE + + ++ +D +A+ + + V++LD NDN PKF++S+Y + EN G+V+ V A DLD G N I YSL S FQ+ TG I+ + P+DREL+E Y L + A D G+ ++ V + I V DVNDN+P + P E SVRE P T + +++ D D G+NA + +S K +D + +++ T + + LD E + + L V D G N R++ + + V+D+NDN+P
Sbjct: 804 NLRSNADAV----VFLSIIDAMQRPPIFEKARYNYYVKEDIPR-GTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIR-----IAKPLDHEAKSQVLLNIQATLGEP-PVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQV-TYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVN----DNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAH----AKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGG-NPPRETVRMLRVEVLDLNDNRP 1363 HSP 4 Score: 159.844 bits (403), Expect = 5.945e-39 Identity = 182/682 (26.69%), Postives = 305/682 (44.72%), Query Frame = 2
Query: 584 VRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHH--KSFQLCLDQQRQPYLFL----LNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD---GLYEARSXXXXXXXXXXXXSPQL----IQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILT------YDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL----EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPF-EFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITV---NGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPR----GLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKP--LSHHYIGHYPIKVSVKDSG 2521
+RV ++V D NDN P F + + E + + L A D D+ P N Q Y + + +F+L ++R L+L LD E Y + I A + + V++ + D NDN P FN S + V EN + + Q+ A+D D+ ++ + + + +++ ++F + I I+ LD+E + +++ V D E + + + V D ND P + + + + ++ E++ G + ++ V D D +T + +L+ G LT Y + DRE S ++ ++ +D L +S +I ++I D NDNPP+F Q Y A+V E GT +L+V A+D D+GLN + YSL E FQID TG+IT + +D E + +L + A D G PL+S+ + +T+ DVNDN P F SV EN I ++ D D G NA V ++ V +G + I LD E + + V D G ++ + +++ DVNDN+P + PR LRE A+S A+S I ++A D D +++Y I+ N + IF + +TG + + +P LS + + +S D G
Sbjct: 158 IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLL-PARDLDLEPYNTQ-RYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDK-EQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDS-----------KTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPP----LHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATD---RGGLSTTAMIKMQLTDVNDNRP-VFYPREYKVSLRESPKASSQASSTP------------IVAVVATDPDYGNFGQVSYRIVAGNE--AGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGG 803 HSP 5 Score: 148.673 bits (374), Expect = 1.822e-35 Identity = 172/694 (24.78%), Postives = 301/694 (43.37%), Query Frame = 2
Query: 578 AVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQL----CLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVL-VKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS---PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKI-LTYDIRTKTA-------FDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-----------EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGS---IPLNSSVGLNITVDDVNDNSPCLLTPFEFSVREN---LAPAT-----IGQLQYEDSDIGRNADVVFSKTWPNDDT--VMITVNGTLYITKPLDRETKD-----RHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDS 2518
A RV + VLD NDN P+F K + E + E + + GS + + TA+D D+ ENA I Y L + SFQ+ R+P LD E + Y + + A + + + V ++V D NDN P V+ V+E P + + ++ A D D + + + + + +++ LFS+ VI LD+E Y++ V +DG R + +L + D + P + V V E++ G V+G + ++ + E + R+ ++L+ I +DI + DRE S+ + + D T++N +S+ T+ +++ D NDN P++ Q V+E P+GT+I A D D G NG + Y L E SLF++DS TG +++Q P+D E + Y L + A+D S L +SV + + + D ND++P ++P + ++ AT + + D D G N + + T N + + + G + + K L T+D R L + +D+G ++SS + + V ++N PR + A +I G + Q+ A A N L+Y I P + + +F + G ++ Y + V V+D+
Sbjct: 1135 AKTRVIVRVLDANDNDPKFQKSKYEFRIEE-NLRRGSVVGVVTASDLDLG-ENAAIRYSLLPINSSFQVHPVTGEISTREP-------LDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSV--EESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALD--TTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQ--------------AVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEI--PAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDA 1799 HSP 6 Score: 138.658 bits (348), Expect = 1.850e-32 Identity = 170/679 (25.04%), Postives = 285/679 (41.97%), Query Frame = 2
Query: 572 LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHK-SFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFN----SSLFSVLVKENTPARSMIFQLIANDPDS-TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG----LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF---SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQ--------LQYEDSDIGRNADVVFSKTWPNDDTV--MITVNGTLYITKP--LDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
L + V I++ DVNDN P F++ R V E + G+ + A+DTD A EN +EY + Q+ R +++ LD E + + + + A + + V + V D NDN P N S S + E+ + ++ +DPDS T ++ + L + + ++++ LD E Y + V TD L+ ++S+ + + ++ P+ Q+ VME + G + QV+ D+D+ + ET E ++ + I T R+ + E Q++VV DG L+S+ T+ V I D NDN P F QS Y VAEN P+G ILKV+A D D G+N ++Y++ F + F++ S +G I + G +D E + Y+ + A D G + + + + +T DVNDN P P E+ V +P Q + D D G V + N+ + + G +++ +P L T+ H L + D G N R + V + +ID P R + + G V+ +IA D A + + Y I + P FS + +G + + KPL H + + G PP+
Sbjct: 266 LRGFMTVNITIQDVNDNQPIFNQSRYFATVPENA-TVGTSVLQVYASDTD-ADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDN-PPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITT---RSHIDCETEPVPQLTVV--ARDGGVPP----LSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLT--DVNDNRPVFY-PREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGG-NLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDI--------------PRGTVVGSVIAASGDVAHRSPVRYSIYSGD--PDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQAT-LGEPPV 911 HSP 7 Score: 137.887 bits (346), Expect = 3.612e-32 Identity = 170/671 (25.34%), Postives = 282/671 (42.03%), Query Frame = 2
Query: 332 VGTIATDIEGLGINLEFHGSLIYKL-----------SGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNL--WSNV--QLLAVVRVRISVLDVNDNIPQF------SKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDL-----DAENQTHYLIKIRAWN-AQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG----------LYEARSXXXXXXXXXXXX----------------SPQLIQNPSV-IEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSD-GWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSS-VGLNITVDDVNDNSPCL-LTPFEFSVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDD-TVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNG 2155
VGTI + + +G L Y+L F +D + L++ +D E++ Q +L ++ L SNV +L V VR+ +LD ND+ P F + +S+A+ + G + A D D + +N Q+ Y + + + ++ Q + L+ L D E + + I A + Q + + LN+ L V ++NPPRF +++ + EN P+ S + Q+ A Y+ LF V +I D E Y +PV+V D + + RS + SP+ + V ENS G VI V+ +D D+ N +I +FS+ S + + DRE+ S+ ++ + SD G S H I + + D NDN P+F+ S+Y V E+ P+GT +++++A D D G+N ++ YSL ++ F ID +G+IT G +DREL+ Y + A D G + S+ V + I V D+NDN P P+ V + P T+ ++Q D+D+G NA++V+S N + +N G L ++ L E+ L V RD G
Sbjct: 1500 VGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAV-------------QEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDAT-RIGEVVAHIVAVDED-SGDNGQLTYEITGGNGEGRFRINSQTG-IIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLS-YEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG-VIHTVVASDLDEG-PNADLIYSITGGNLGNKFSIDSSSGEL-------SARPLDREQHSRYTLQIQASDRGQPKSRQGHCN----ITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKG 2140 HSP 8 Score: 116.316 bits (290), Expect = 1.304e-25 Identity = 122/409 (29.83%), Postives = 178/409 (43.52%), Query Frame = 2
Query: 1448 TYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-----EHDFSLFQIDSTTGVI----TVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFS-VRENLAPATIG----QLQYEDSDIGRNADVVFS-KTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSL-DKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFIT---NKPAKYDDKLQSNN 2608
T +IRTK DRE + S+V I G N + V + D NDN P F Q+ EN P + A DLD Y++ F L GV+ + G +DRE Y L I A+D G+ PL + +NIT+ DVNDN P F+ V EN AT+G Q+ D+D N V ++ +D M ++ G +YI K LD ETK+ H L V +D+G +++ V IRV DVNDN+P + + + D SP S+S PG + + I+V D D+ ++ L + + YL + PL + +Y + V D G+PPL K +L IT + P +++ L N
Sbjct: 129 TGEIRTKVKLDRETRASYSLVAIPLSGRN----------IRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPEN---ATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHG-EQPLETTAFVSIRVTDVNDNQPTI----NVIFLSDDASPKISES------AQPGEFVAR-ISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHAN 512 HSP 9 Score: 115.931 bits (289), Expect = 1.624e-25 Identity = 161/580 (27.76%), Postives = 265/580 (45.69%), Query Frame = 2
Query: 572 LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDL--YQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQN---------PSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDI-RTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLN------ITVDDVNDNSPCL--LTPFEFSVRENLAPA--TIGQLQYEDSDIGR--NADVVFSKTWPNDDTVMIT--VNGTLYITKPLDRETKDR-HCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL 2230
L + + I + D NDN P+FS+++ VSE ++K G+ + A D+D A NA++ Y + + + ++ + LD E + Y +KI A + + + + + D NDN P F + V V E T ++I + AND D+ L + L T + E +F++ + +++ LDYE Q Y++ V +D +EAR+VL V V DEND +P + P++ E+ E+ + V TD D N K+I E + S+G +++ ++ R + A S V +I D + L SS + VQ D +F Q+QY A ++E P+G+V+L++ LD L I + E F L Q + I + P+DRE + YKL + PL SS+ + IT+ D NDN P +E + E LAP +I QLQ D+D N++VV+ T ND+ + V G L++ LD ++ + + L +R D+ S + + D NDN+P+
Sbjct: 2302 LASYAELVIELEDENDNSPKFSQKQFVATVSEGNNK-GTFVAQVHAFDSD-AGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNG----VVSVNMSRLQPAV--SSSGDYFVRIIAKDAGKPA----LKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSL-AIIAGNEESAFELLQ----SKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISE-LAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKF 2862 HSP 10 Score: 113.235 bits (282), Expect = 9.661e-25 Identity = 174/731 (23.80%), Postives = 302/731 (41.31%), Query Frame = 2
Query: 422 CFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQ----FSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN-DLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS---PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIG-----TVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGP--VDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPATI-GQLQYEDSDIGRNADVVFS--KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVR--LRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSP--GYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
F ID ++ + I K +D E+ +EL + H E ++ A V +R++ DVNDN P F +SE S + G + + D D E A + L F L + YL +++ LD E ++Y + + A + ++ L + D NDNPP F L+ V E + + Q++A+D D S L + L +T + F + +I S +D E ++ V DG S ++ +D + P Q+ + V EN G I +V +D D E + EF + S + + ++ F+R S + V+ G +T+A I +Q+ D NDN P F +Y + E+ T I+ V A D D G G++ Y + ++ +F+ID +TG I V P + + + L+I A D G++ N+ + +++ D P + + V+E++ T+ G + D+ + V +S P+ + T +G + I KPLD E K + L ++ L + + G Q V I V DVNDN P + + ISV +S G + A D D ++ ++TY ++ + +F+ ++ +G+L L + L + + + V+ D G P L
Sbjct: 335 MFRIDPRTGAIYINKALDFET----KELHELVVVAKDHGE------QPLETTAFVSIRVT--DVNDNQPTINVIFLSDDASPKISE-SAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTT-RDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHA-QWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELD----FERRSSYEFPVLATDRGGLSTTA--------MIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQ----VNIEVEDVNDNAPEF----------------EASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESG--KGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSL 1016 HSP 11 Score: 91.2781 bits (225), Expect = 4.631e-18 Identity = 138/628 (21.97%), Postives = 258/628 (41.08%), Query Frame = 2
Query: 371 NLEFHGSLIYKLSGPNCC-------FSIDQKSSVLTIAKNIDLESICINRELSSDC-SSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQR------IERHVSEASHKAGSHIFLET--ATDTDIAPENAQIEY-------GLAEHHKSFQLCLDQQR-QPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSV----------IEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAF-------DREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL------EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLT-PFEFSVRENLA-PA--TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPL 2101
+++ + +L Y+L + F++D+ S L + + +D E + +E D +S H + V+ VR++ D NDN P F Q+ I +SE S L T ATD D N+++ Y G + H + + ++ R QP + D Y ++I A +A + + + +D +F + + + E P S++ QL + D + L A NE F +LQ+ ++L+ LD ER+ YK+ + ++ + L N + E+ E + I Q+ D D T + + ++SG ++ + T D+ T F D S ++ C ++ L S +++ D NDN PKF ++Y +AEN P+G+ + + +A DLD G G+++YS+ E + +F++DS +G++T D E ++ Y + + A D G +SV + + ++ ++ +P + F + +A P +GQ+ DSD G + VV+ + P+ + +G + I + L
Sbjct: 2453 DVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYE---LQQEYELDVIASDAAH-----------EARTVLTVRVN--DENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGD--------YFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQS------LAIIAGNE-ESAFELLQSKAIVLVKP-LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVV----------YDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRAC----DSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGG--KKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSHFKVNRSSGAVLIKRKL 3032 HSP 12 Score: 90.1225 bits (222), Expect = 1.068e-17 Identity = 106/423 (25.06%), Postives = 179/423 (42.32%), Query Frame = 2
Query: 1424 SGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLA-PATIGQLQYEDSDIGRNADVVFSKTWP-------NDDTVMIT---------VNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLI--NPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYI---GHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGGS 2617
S ++++ LT + A + ++I VVL+ T+ L S + +++ D NDN PKF Q Q+ A V+E GT + +V+A+D D G N ++ Y + HD + + +G++ +DRE+++ YKL I A D G + + + + + DVNDN P +V E A I + D D T+P + TV I +G L + + LD E + + L V D R + +RV D NDN P + P I A S S+S+S+ + + + A D D N +I+ P + FS + + G +S++ + G Y +++ KD+G P L + ++Q+N+ GS
Sbjct: 2266 STRSQRALT---SSSFALTNSQPNEIRVVLVA----RTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVD-----------TYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTV----LTVRVNDENDNAPVFLAQQPPAYFAILPAIS-EISESLSVD------FDLLTVNATDADSEGNNSKVIYIIEPA---QEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLL-------------RVQANDNGS 2643 HSP 13 Score: 74.3294 bits (181), Expect = 7.289e-13 Identity = 175/685 (25.55%), Postives = 294/685 (42.92%), Query Frame = 2
Query: 536 LELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL-AEHHKSFQ----LCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNS----SLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNE--------LRKLFSV-LQNGTVILISSWLD--YERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSS--QISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKF-RQSQYFAHVAENGPIGTVILKVNAYDLD--DGLNGKIHYSLE--HDFSLFQIDSTTGVITVQGPVDREL-KEHYKLHIHAVDSG-SIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVREN-LAPATIGQLQYEDSDIGRNADVVFS-KTWPNDDTV--MITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRV-IDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPL 2467
L++I Q+ +R+ ++DVNDN P F + VSEA+ + G+ I +A D D P + Y L AE + LD+ L L LD E Q Y + + A +A + + + V+D NDN P F + + F++L PA S I + ++ D D +V D NN ++ FSV NG V + S L Y V + D ++ ++L V D Q +QN ++ E + G V+ Q+ +D + +I +E + F L K ++ DRE++ ++ +VL G ++++ +S ++ + ILD NDN P F R ++Y A ++E P+ I ++ A D D + N ++ Y + +D +F ID TGV+ V +D + + Y+L I A DS PL S + + D NDN P LT + + EN +++ + D D G + +S P+D++ M V+ G + D E + R+ + + D G G++ S V +RV I+ D R R + PAA V GYV+ Q+ A D D + ++ Y + P++ F N ++G + + + L
Sbjct: 2396 LKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVT-VSEAT-ELGAVITSISANDVDTYP---ALTYRLGAESTVDIENMSIFALDRYSG-KLVLKRRLDYELQQEYELDVIASDAAHEARTV---LTVRVNDENDNAPVFLAQQPPAYFAIL-----PAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQL---GQDALDQSLAIIAGNEESA----FELLQSKAIVLVK-------PLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMG--GKKAS---VAVRVEIESRDEFTPQFTERTYRFV----LPAA-------VALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSH----FKVNRSSGAVLIKRKL 3032
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Match: ft (gene:FBgn0001075 transcript:FBtr0077478) HSP 1 Score: 185.652 bits (470), Expect = 8.255e-47 Identity = 183/688 (26.60%), Postives = 301/688 (43.75%), Query Frame = 2
Query: 584 VRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQP-----YLFL--LNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYK---------VPVFVTD---GLYEARSXXXXXXXXXXXXSPQL-----IQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVR-------ENLAPATIGQLQYE-DSDIGRNADVVFS------KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSL--DKPLSHHYIGHYPIKVSVKDSG 2521
+ VRI VLDVNDN P+F + I SE S +G+ + L+ ATD D+ +Y + + + L P YL L +LD E++ Y + I A + ++ L V++ + D NDNPP F+ S ++V + E + + ++A+D D + Y E F+V VI + ++ + K VF D + R+ + V + D ND P + V V EN+ G V+ V V D D S NG+ + F L + I +R DRE+ + ++ ++ D T A T++ + + + D ND+ P F +S+Y A ++E P G+ + + A D D G+N ++HY + ++ F +D TG+I GP+DRE+++ +L I A D G P + L + + D ND +P +FS R E+ P TI L D D G N V F+ + +P + + G L +PLDRE ++ + V RD G + ++ V + V DVNDN P+ + + I + ++ + A D DD N + Y + + +F ++ +G +SL D P S H+ HY + VS +D+G
Sbjct: 140 IEVRIKVLDVNDNSPEFPEPSIAISFSE-SATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLA---ETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSD-SGLNGRTSVRIVSGNELGHFRLEEAADLHI----VRVNGVLDREEIGKYNLTVVAMD-QGTPAR---TTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAP------QFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPL-QFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSL-----ADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRL---ESGGEGLFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAG 799 HSP 2 Score: 158.688 bits (400), Expect = 1.627e-38 Identity = 195/762 (25.59%), Postives = 327/762 (42.91%), Query Frame = 2
Query: 380 FHGSLIYKLSGPNCC--FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELR----KLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX------SPQLI-QNPSVIEVMENSGKGLVIGQVIVTDKD-DSQTNGKMICEHETTEPRLEFSLSSGKNKKILTY--------DIR-------TKTAFDREK-SSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQ-SQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS---------LFQIDSTTGVITVQGPVDREL-KEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN-GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
+G + Y L+ N F++D + L++ + +D ES I+ + + H L SN + I VLD NDN P+F++ E V E S G+ + A+D D N+Q+ + ++ ++ +D L+L LD E+ T Y + I A + + ++ V D NDNPP F S+ +KE P ++ I + A+DPDS + Y + E + + F + VI +D E +++ V TD + L +P + N +++ ++ KG + V KD DS +NG ++ + P+ F L +N I+T+ ++R T A E+ SS++ + +I + +++ P+F Q S+ V EN PIGT IL V A+ + +I Y + + + LF ID+ G+++ +DRE E Y++ ++A+ G P S + +TV D ND+ P L TPF ++V E+L TI L+ D D V F +D ++ + G L + LDRETK ++ LR+R+ D G + + I+V D NDN P + S I GY + Q++A D D N +L+Y ++ + + +FS N TG L+L L + + HY + V +D+G P L
Sbjct: 1309 LNGDVYYSLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKH-----PLSSNAS------ITIVVLDENDNAPEFTQSSSEVSVLETS-PTGTELMRFRASDADQG-VNSQVVFSISAGNRRDTFHIDSITGS-LYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVS-YAISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNG-LVTYEIVSGPQELFKLQ--RNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSV-------------------PQFEQRSKLSGSVYENEPIGTSILTVTAH----LASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDT--LGSVTFLLMDGHDGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSD----GVQYTEAYATIQVSDTNDNPPLFED--------------TVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVV--SDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSL 2007 HSP 3 Score: 144.821 bits (364), Expect = 2.371e-34 Identity = 200/728 (27.47%), Postives = 296/728 (40.66%), Query Frame = 2
Query: 539 ELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWN---ELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL--YEARSXXXXXXXXXXXXSPQLIQN-------------------------------PSVIE-----VMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPR---------LEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-----EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSG-SIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPATIGQL----QYEDSDIGRNADVVFSKTWPNDDTVMITV-NGTLYITKPLDRETKDRHCLRVRLRDNG---LNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQ---SPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDS 2518
EL + + VQ I V D NDN P F + E + + G + A D D+ +NAQ+ YG+ + L+ Q L L LD E HY++ ++A QDN Q + + V V D NDN P F+ +S V EN P + + + A D DS + + Y ++ F + NGT I LD E Y + V D + + S LE SP+ Q P I +MEN V+ V D D+ + NG + ++ E R L FSL+ + +R A DRE S + + D ++ + ++ILD NDN P F QY A VAEN IG ++L+V+A D+D+G NG+I YS+ HDFS I TGV+ V ++ E Y L + A D P + L I + D+NDN P L +P+ V EN P G + Y+ N+ V + + D I +G + + KPLDRE + + L + D G L G +G V + V D+NDN P + E+ QS +V + S +V+T A D D+ N KL +++L + F +S TG +S L Y + + +DS
Sbjct: 1892 ELRIRVSDGVQYTEAY-ATIQVSDTNDNPPLFEDTVYSFDIPENAQR-GYQVGQIVARDADLG-QNAQLSYGVVSDWANDVFSLNPQTG-MLTLTARLDYEEVQHYILIVQA---QDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIE-YSITAGDVDSEFGIDSNGT-IRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIMENVAINTVVIAVKAVDNDEGR-NGYI--DYLMKEARDEDMGQSDPLPFSLNPTDGQ------LRVVDALDRELRSSYLLNITARDRGEPPQ----STESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHDFS---ISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTG----TGIVRVEVQDINDNDP-------VFEL---------QSYHATVRENLPSGTHVLTPR-ATDKDEGLNAKLRFNLLGEHM---HRFHIDSETGEISTATTLDREETSVYHLTLMAQDS 2570 HSP 4 Score: 142.124 bits (357), Expect = 1.887e-33 Identity = 152/513 (29.63%), Postives = 227/513 (44.25%), Query Frame = 2
Query: 569 QLLAVVRVRISVLDVNDNIPQF---SKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLND----------LDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXX----XXXSPQLIQNPSVIEVMENS--GKGLVIGQVIVTDKDDSQTNGKM-ICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSG-SIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFS 2032
+L + V+V I + DVND +P F ++ I +V+ + + A D D N I+Y + E Q P F LN LD E ++ YL+ I A + + Q E + + + D NDN P F+ +S V EN +M+ Q+ A D D + R Y + FS+ ++ V+ ++ L+YER RY + V D E + + ND P + +P + VMEN+ G + V D D N ++ E + SSG DI DRE+ S+ ++ L+ D + + LT + + V++ D NDN P F Y A V EN P GT +L A D D+GLN K+ ++L EH F IDS TG I+ +DRE Y L + A DS + P SSV L I+V DVNDN P T + +V E ++ + + D D G NA V ++
Sbjct: 2146 RLSSTVKVTILIKDVNDEVPVFISANETAIMENVA-----INTVVIAVKAVDNDEG-RNGYIDYLMKEARDEDM----GQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRI-RYSIVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSG--------DIALLKPLDREQQSEYTLTLVAMD----TGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEH-MHRFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYT 2634 HSP 5 Score: 140.969 bits (354), Expect = 3.561e-33 Identity = 187/754 (24.80%), Postives = 311/754 (41.25%), Query Frame = 2
Query: 332 VGTIATDIEGLGINLEFHGSLIYKLS-GPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQ----QRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXX---XXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSA---NIH-LTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTW-PNDDTVMITVN-GTLYITKPLDRETKDRHCLRVRLRDNG-LNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDAT-NTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPP 2530
+G+ + ++L + + Y S P F I+ +S +T+A ++D E Q ++ + S+ A + I++ D NDN P+F E ++ + + ATD D N+ I Y L + F + ++ F + + Y + + A + ++E V++ + D ++NPP+F + + + ++ I ++ AND D Y L +FSV ++ I + + + RY++ V TD +S +V EN ++P+ N + V EN G I V TD DD+ NG L +S+S G ++ + D RT ++ Q+ LI N + H L+S + + + D NDNPP F +Y ++ EN P+GT + + +A D D N IHY+ D F ++ + G I+ D E + Y L I A + S + S L + V VN+ P L P F F V E A T +G +Q D D G + V + ND I N G +Y+ + LDRET++R L V ++ G + G +V I + D ND P I I +A +P ++ +T + A+D D T N + +Y I+ N Q F + TG +S L Y + + D+G PP
Sbjct: 2927 IGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGNITVAGHLDRE---------------QQDEYILKVVASDGAWRAETPITITIQDQNDNAPEFEHSFYSFSFPEL-QQSIALVGQIIATDRDKQGPNSVISYSLQQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMD-YSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATD-DDTGPNGM-----------LRYSISGGNERQDFSVDERTGGIVIQQ---QLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDS-SMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKGFRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEA-APVGTK-------------VTTVKAIDKDVRTQNNQFSYSIINGNL--KQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPP 3630 HSP 6 Score: 135.576 bits (340), Expect = 1.578e-31 Identity = 209/787 (26.56%), Postives = 335/787 (42.57%), Query Frame = 2
Query: 302 IQENEPIDRMVGTI-ATDI-EGLGINLEFH--GSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAV-VRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN-DLDAENQTH----YLIKIRAWN--AQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISS-WLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSP---QLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPF-EFSVRE-NLAPATIGQLQYEDSDI-GRNADVVFSKTWPNDDTVMITVNGTLYITKPLD-------RETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
++EN P V T ATD EGL L F+ G +++ F ID ++ ++ A +D E + HL L+ S + A V + ISV DVNDNIP+F V E K G +F A D D ENA + Y ++ + + D + + +L + ++H Y I I A + Q EL V L + +S F++ E+ MI ++ A P V + Y A + V N ++ + LDYE Y++ + DG + +++ + V D ND +P QLI N EV+E +I V +D+D S NG +I RL+ G + + +I T+ DRE+ + V+ D H+T + ++ + +LD NDNPPKF + + +V EN IG+ +++V + DLD G N YS E+ F+I+ +G ITV G +DRE ++ Y L + A D + + IT+ D NDN+P F FS E + A +GQ+ D D G N+ + +S P+ + G ++ K + R ++ + L V DNG S V I ++D ++N P+ E + +P ++ G I ++ A D D ++ Y ++ N S IFS G+++L KP+ Y + V D G PP DE + +T +
Sbjct: 2500 VRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHR-------FHIDSETGEISTATTLDREETSVY------------HLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISK-GEFVFGARALDLDDG-ENAVVHYTISGRDQHY---FDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELFPTFAYMANSHFAM--SEDVRPGKMITKVSATSPKKGLVGKI-RYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYN---AEVLEEESPPQLIAVVKASDRD-SGDNGNVIY-------RLQNDFD-GTFEITESGEIYTRMRLDREEIGDYAFVVEAVD----QGVPHMTGTASVLLHLLDKNDNPPKFTR-LFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASDGA---WRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNG-KPPLYSECLVNINIVDAHNNPPKF-------EQAEYLAPLPQDAVR-------GQRIVRVHANDKQDLGTNEMDYSLMTFNL--SSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGE 3222 HSP 7 Score: 134.035 bits (336), Expect = 5.244e-31 Identity = 174/703 (24.75%), Postives = 291/703 (41.39%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL-AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQ-DNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYE----RHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPR------LEFSLSSGKNKKILTYDIRT------KTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF-SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIG----QLQYEDSDIGRNADVVFSKTW-PNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVD-DDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGH-------YPIKVSVKDSGSPPLIDEKMFYLFIT---NKPAKYD 2587
VR+ V D+NDN P F Q V E + +G+H+ ATD D NA++ + L EH F + + LD E + Y + + A ++ + + +N+ + V D NDN P+F+S+ ++V V E +F A D D +V+ + T + + F + N ++S+ L+ + H + ++ +S+ P+L M NS + + GKMI + T P+ + ++++ G L D + + D E + + + +DG S L S I + + D NDN P Q Y A V E +I V A D D G NG + Y L++DF F+I + +G I + +DRE Y + AVD G + + + + + D NDN P F +V EN A IG ++ D D+G NA+ +S + P + + +G + + LDRE +D + L+V D G ++ + I + D NDN P + + P QSI++ + Q+IA D D N+ ++Y + PS +FS + TG + K + + + Y + V D+G PPL E + + I N P K++
Sbjct: 2477 VRVEVQDINDNDPVFELQSYHATVRE-NLPSGTHVLTPRATDKDEG-LNAKLRFNLLGEHMHRFHI---DSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHY----TISGRDQHYFDI--NTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELF---PTFAYMANSHFAM----------SEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPS----LRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGTFEI-TESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRLFSLNVTEN---AEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASD----GAWRAETPITITIQDQNDNAPEFEH-----SFYSFSFPELQQSIAL---------VGQIIATDRDKQGPNSVISYSL----QQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFE 3125 HSP 8 Score: 131.339 bits (329), Expect = 3.794e-30 Identity = 150/562 (26.69%), Postives = 244/562 (43.42%), Query Frame = 2
Query: 587 RVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVT--DGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAF-----DREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLD-DGLNGKIHYSLEHD--FSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFS--VRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDN 2218
RV I V N + P+FS + V E + GS I ATD D P N + Y ++ ++ +D+ R + + LD + Y + I + + + + + + D NDNPP FN + + EN P + +FQ A D DS +++ + + + R F + Q+ I + DYE + Y + + D E+ + L V V N+ PQ +Q +V E S G +G V TDKD + + R+ + L N K D T + DRE +++ + ++ + + N + I++Q D ND PP+F + Y + ++E P+GT + V A D D N + YS+ + F+ID TG I+ +DRE Y L I A+D+G P S ++I ++DVNDN P TP + + EN T I L D D+ RN + ++V+ G + T DRE + + D+G +++S + I V+D NDN
Sbjct: 3214 RVVIVVTGENMDTPRFSVNSYQVIVPE-NEPVGSTILTVGATDDDTGP-NGMLRYSISGGNERQDFSVDE-RTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPD--RHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRVGAVQATDKDSGE------------DGRVYYLLVGSSNDKGFRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQ--DGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPT-FTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSG-KPKQKSQHLLTITVLDQNDN 3753 HSP 9 Score: 130.954 bits (328), Expect = 4.344e-30 Identity = 104/394 (26.40%), Postives = 169/394 (42.89%), Query Frame = 2
Query: 1466 KTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRE---------------------LKEHYKLHIHAVDSGSIP-LNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTV--MITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITN 2569
+ DRE+ ++ + C D S +S + + ++D NDN P+F S + + EN P T + K+ A D D G N ++ ++L F ID+ G I P DRE + +Y L V IP L V + + V DVNDN+P L P+ ++ E + T I + +D+D G N DV +S N+ + + G L + + LDRE+++ H L V +D L S+ + I V+D NDN P +S +S+ G + + A D D N+++ + I N F +S TG L L KPL + I Y + ++ D G+P L ++ + + +
Sbjct: 1108 RAPLDREERDYYALTVSCRDAGQPSR----SSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQ--------------SSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNR--RDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVD 1481 HSP 10 Score: 130.568 bits (327), Expect = 5.598e-30 Identity = 170/667 (25.49%), Postives = 273/667 (40.93%), Query Frame = 2
Query: 302 IQENEPIDRMVGTI-ATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLE-----SICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQF-SKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKS-FQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXS---PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPK-FRQSQYFAH----VAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF--SLFQIDSTTGVITV-QGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL--LTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL 2230
+ EN I MV + ATD++ G N S++ L N FSI + + V+ +AKN++ E S+ + E DC+ + N + L I++LD+NDN P F + R + G ++ A D D P N+Q+ Y L E F++ + LL LD E Q+ Y + + A + V + V D NDN P F + V+EN P+ + + A D D + LRF+L E F + I ++ LD E Y + + D + E R+ L +D + P+ + V E KG + D DD G+ H T R + +++ + KT ++V+ D S L+S + V + PP+ F Y A+ ++E+ G +I KV+A GL GKI Y++ ++D +G+++V Q +D EL Y++ I A D + L S + + V D NDN+P + L + E P I ++ D D G N +V++ D T IT +G +Y LDRE + V D G+ + V + ++D NDN P+
Sbjct: 2287 VAENASIGAMVLQVSATDVDE-GANGRIRYSIV--LGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAE---DCA--------LENPAGDTAELT-----INILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSGD---IALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLL----GEHMHRFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDD----GENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQS----LSSKAELTVIL-----RPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGTFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVP-HMTGTASVLLHLLDKNDNPPKF 2913 HSP 11 Score: 127.487 bits (319), Expect = 4.713e-29 Identity = 202/794 (25.44%), Postives = 329/794 (41.44%), Query Frame = 2
Query: 299 LIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNC-CFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIF-LETATDTDIAPENAQIEYGLA---EHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWN-AQDNKQWNELNVDLYVDDFNDNPPRFNSSLF---------SVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQR--YKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIE-VMENSGKGLVIGQVIVTDKDDSQTNG---KMICEHE---TTEPRLEFSL-----SSGKNKKILTYDI----------------RTKTA--FDREKSS--QISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKF---RQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVM-ITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQI--FSFNSTTGYLSLDKPLSHHYIGHYPIKVS 2506
++ E P V +I E G+N + H + LSG FS+D + ++ +D E I ELS G + + A ++++ +LD ND PQFS++ E++V+ I L TATD D N + + LA E Q LD L LD E + Y I + A + Q V L V D NDN P+F + + +K+ ++ + A+D D + + E LF + I + H + YK+ V D + RS Q +++E V+++ + L GQ +Q G +M+ +HE ++P E + ++GK + YDI R TA DRE+ + +++++ S + +A+ +N+ I+D NDN P F R+S+ + EN +G I D D G+N +I YSL ++ + F+I TGV+ +Q P+ E + + A D+GS PL+S + L++ + DVND++P T +E S+ E T L D D+G N + + N + + + +G L++ PLDRE +D + L V RD G R S V I VID NDN P+ N ++ + SI + +L AVD D N +L++ TL SQ F+ ++ G++ +P + +KVS
Sbjct: 502 VLSELAPTGSFVASITATDEDTGVNAQVHYDI---LSGNELKWFSMDPLTGLIVTTGPLDRE-IRDTVELSISARDGGPNPKF-----------AYTQLKVIILDENDEAPQFSQR--EQNVTLGEDAPPQTIVALMTATDHDQG-TNGSVTFALAPSVERLYPLQFALDALTG-QLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGGE--GLFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDA-GQRRS-----------------QQDAIVEIVLKSKLEMLECGQ--------AQAGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVFPDGYLFVRAPLDREERDYYALTVSCRDAG-QPSRSSVVPVVIHVIDENDNAPQFTN--------------STFTFSIPENAPADTFVGKLTAVDRDIGRNAELSF------TLSSQTQDFTIDTRNGFIKTLRPFDREAL----VKVS 1223 HSP 12 Score: 120.939 bits (302), Expect = 4.481e-27 Identity = 156/658 (23.71%), Postives = 278/658 (42.25%), Query Frame = 2
Query: 572 LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTK-TAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLE--HDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVREN-LAPATIGQLQYEDSDIGRNADVVFSKTWPND--DTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGS 2524
L +V + ++V D NDN P + V E I + A+D D + +N + Y L F + ++ LD E Y + A + +V L++ D NDNPP+F + LFS+ V EN S + ++ ++D D + Y + N K Q+G I ++ LD E+ Y + V +DG + A + + + ++D+ND +P+ + E ++GQ+I TD+D N + + +P FS+ + +R K + + R + ++ ++ +D L S +N+ I+D ++NPPKF Q++Y A + ++ G I++V+A D D ++ YSL + S+F + G IT+ P+ Y+L + A D G P + + I V N ++P + ++ V EN +TI + D D G N + +S + N+ D + G + I + LD + + L + ++D G + S + I + DVNDN P + N + P G + Q A D D N + ++ LP+ F N + G +S + Y +++ K+ S
Sbjct: 2790 LRSVTLITLNVTDANDNAPVMEQLIYNAEVLE-EESPPQLIAVVKASDRD-SGDNGNVIYRL---QNDFDGTFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKF-TRLFSLNVTENAEIGSFVIRVTSSDLDLGANANAS-YSFSENPGEKFRIEPQSGN-ITVAGHLDREQQDEYILKVVASDGAWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNS--VISYSLQQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPP----LYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYH-PLSSVAMLTIILTDVNDNPP-VFNHKEYHCYIPENKPV-------------GTFVFQAHAADKDSPKNA-IIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDS 3417 HSP 13 Score: 118.627 bits (296), Expect = 2.641e-26 Identity = 202/833 (24.25%), Postives = 340/833 (40.82%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSG--PNCC----FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSH--IFLETATDTDIAPENAQIEYGLAEHHKS-FQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWN--AQDNKQWNELNVDLYVDDFNDNP---PRFNS-SLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANN---ELRKLFSVLQNGTVILISSWLDYERH-QRYKVPVF---VTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDK-DDSQTNGKMICEHETTEPRLEFSLSSGKNKKIL----TYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS--LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFS--VRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVM-ITVNGTLYITKPLDRETKDRHCLRVRLRD-----------------------------------NGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTY--------HILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I+E P+ + T+ D G+N G + Y +S P F I+ ++ V+ + ID ESI R Q S QL V + V D+NDN P F + S GS + A D D + N + Y + + F+L Q+ + + + Y + +++ + Q ++ +E+ + + + P+F S S V EN P + I + A+ S + F TA ++ +LF + ++ ++ LD E + Y+V V+ + +R+ + V V D+ND PQ + P V V E+ L IG I T + D T G + F L G + K L T + DRE S+ + + SDG + T ++ +Q+ D NDNPP F + Y + EN G + ++ A D D G N ++ Y + D++ +F ++ TG++T+ +D E +HY L + A D+G L++++ + V D+NDN+P + P +S V EN+ AT + + +D D G N + +S T + D+ I NGT+ + LDRE + + L V RD + R S+ +V I + DVND P I+ A A ++++I+ V+ + AVD+D+ N + Y + + LP FS N T G L + L Y + ++ +D G PP E + I ++
Sbjct: 1498 IKEGIPLKTPIVTVTADDPDSGLN----GKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQ---------PSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDAD-SSSNGLVTYEIVSGPQELFKL---QRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHLA-SAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSED----LQIGHTISTLRAHDPDTLGSVT-----------FLLMDGHDGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSDG------VQYTEAYA-TIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAP-IFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFIS---------ANETAIMENVAINT------VVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLP---FSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDE 2271 HSP 14 Score: 109.768 bits (273), Expect = 1.320e-23 Identity = 189/791 (23.89%), Postives = 317/791 (40.08%), Query Frame = 2
Query: 290 LKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLES---ICINRELSSDCSSGQGH-------LELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQ-THYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXX--XXSPQLIQNPSVIEVMENSGKGLVIGQVIVT---DKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDN------------PPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMIT----------VN---------GTLYITKPLDRETKDRHCLRVRLRDNGLNGR-RQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKD 2515
+ I EN P D VG + +G N E L + LS F+ID ++ + + D E+ + N E S + S +G LE V+ +L V+V++ V DVNDN P+F + +SE + + G+HI D D N + Y LA+ +++ Q LD L L LD E+Q H+LI + A + + ++ + V D NDN P F S V V E +P + + + A+D D + +A N R F + + + LDYE Y + + +D + S + +++P + + +++ ++ +G+ + IVT D DS NGK+ EP+L G N + T I T DRE + ++ +D S L++ + V + D NDN PPKF S+ + T +++V+A D D NG + Y + LF++ TG+IT + + Y+L + + D S + IT+ P +F R L+ + YE+ IG + V + + +T V+ G L LDRE V + L G+ R S +V + V+D ND+ P+ ++ + + S+ + I G+ I+ L A D D T +T+ ++ + F +TG L L+ L Y +++ V D
Sbjct: 1158 FTFSIPENAPADTFVGKLTAVDRDIGRNAE----LSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASE-GTHITHVFTQDADEG-LNGDVYYSLAKGNEAGQFNLDSATG-QLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNR-RDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIK---EGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTE--TGVIHTLREIDRESIDTFRLTVVATDRAQPSER-QLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSS---------TAVMQVHAKDADSSSNGLVTYEIVSGPQELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVP-QFEQRSKLSGSV-----YENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEE-YEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNV--------SEDLQI------GHTISTLRAHDPD--TLGSVTFLLMDGH---DGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSD 1899 HSP 15 Score: 107.842 bits (268), Expect = 4.452e-23 Identity = 98/342 (28.65%), Postives = 150/342 (43.86%), Query Frame = 2
Query: 1571 INVQILDFNDNPPK-----FRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKI-----------HYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPNDDT--VMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNT---LPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
+ V +LD ND+ P F A V EN GTV+ V D D GLNG+ H+ LE L ++ V G +DRE Y L + A+D G+ ++ L I V+DVND+ P +V LAP + + + D D G NA V + N+ M + G + T PLDRE +D L + RD G N + + ++ + ++D ND P+ RE Q++++ P ++ + A D D TN +T+ L P+ P Q F+ ++ TG L+ +PL + Y I V +D G+P
Sbjct: 368 VTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLH-------IVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYT-QLKVIILDENDEAPQFSQ----RE----------QNVTLGEDAPPQTIVALMTATDHDQGTNGSVTF-ALAPSVERLYPLQ-FALDALTGQLTTRRPLDREKMSQYEISVIARDQGAP 685 HSP 16 Score: 103.219 bits (256), Expect = 1.335e-21 Identity = 174/714 (24.37%), Postives = 278/714 (38.94%), Query Frame = 2
Query: 596 ISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYG--LAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWN-AQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENT--PARSMIFQLIANDPDS---TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIE-------VMENSGKGLVIGQVIVTDKDD---SQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLE-HDFSLFQIDSTTGVITVQGPVDRELKEH----YKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPF------EFSVRENLAPAT--------------IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKP---RLI-NPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNST-TGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK---PAKY 2584
I +LD NDN P F ++ V+E + G+ + +ATD D N +I Y L + + F + D + + +L+ E + Y + +RA + A +N + + + + D NDN P F S + V ENT P + + A D D+ S +R+ L + ++ LF + + I + LD E+ Y + + D S E + N V E V EN G + TDKD+ ++ ++ EH R +G +I T T DRE++S + L+ D T SS + + + D NDN PKF + Y V E G + A DLDDG N +HY++ D F I++ TGV++ + + + K H Y + I A+D G L+S L + + P L F F++ E++ P +G+++Y + G D + + PN + + +G LD E + + + D R S + + V D NDN P +LI N L E +SP +I + A D D N + Y L N +F T +G + L IG Y V D G P + L + +K P K+
Sbjct: 2266 IRILDENDNSPVFDPKQYSASVAENA-SIGAMVLQVSATDVDEG-ANGRIRYSIVLGDQNHDFSISEDTG---VVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSD----LFRINASSGDIALLKPLDREQQSEYTLTLVAMD----TGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMH---RFHIDSETG--------EISTATTLDREETSVYHLTLMAQDSSITEPR---ASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVIL-----RPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAG-GIMGDSL--RVDPNSGLLSVGQDG-------LDYELTHLYEIWIEAADGDTPSLR-SVTLITLNVTDANDNAPVMEQLIYNAEVLEE------------------ESPPQLIAVVKASDRDSGDNGNVIYR--LQNDFDG---TFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKF 2913 HSP 17 Score: 89.7373 bits (221), Expect = 1.791e-17 Identity = 102/386 (26.42%), Postives = 151/386 (39.12%), Query Frame = 2
Query: 1457 IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYK---------LHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEF--------SVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPND----------DTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPP 2530
+ T DRE + + DG + +L +NV ILD NDNPP F S Y + E GT ++ V A D D G N KI Y L F ++ TGVI+ V+ + + K + A D GS + + + + D ND+ P + F F +V EN T + + +DSD G N N+ D ++ VNG LDRE ++ L V D G R ++ + I V DVND++P + S +S G + + A D+D N ++ Y IL N L + FS + TG + PL + +S +D G P
Sbjct: 222 LETTGNLDRESRGSYQLNISARDGGSPPRFGYLQ----VNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPII--SFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGV------LDREEIGKYNLTVVAMDQGTPA-RTTTAHLIIDVNDVNDHEPVF--------------EKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNEL--KWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNP 578 HSP 18 Score: 83.5741 bits (205), Expect = 1.104e-15 Identity = 101/439 (23.01%), Postives = 177/439 (40.32%), Query Frame = 2
Query: 1286 IEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGK------IHYSLEHDFSLFQIDSTTG-----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDR-----------ETKDRHCL-RVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
EV+E +G +G + K + N EP EF+L +T +++T DRE +++ S T + +++LD NDN P+F + +E+ GT +L A D D G NG + ++++ F L + +G + G +DRE + Y+L+I A D GS P + +N+T+ DVNDN P + + S+ E P T + + D+D+G N+ + + + + TVN + +R + C+ V RD+G + R+ V + ++D ND+ P + R D A +++ G V+ + D D N + + I+ N L + + ++ L IG Y + V D G+P
Sbjct: 71 FEVLEGQPRGTTVGFIPTKPKFSYRFN----------EPPREFTLDP------VTGEVKTNVVLDREGMRDHYDLVVLSS--------QPTYPIEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITY---YLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHG-SPRQDGRTYVTVNLLDTNDHDPII----SFRFFPDGGKVATVDENAVN-----GTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTP 472 HSP 19 Score: 65.4698 bits (158), Expect = 3.755e-10 Identity = 111/453 (24.50%), Postives = 184/453 (40.62%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSI-DQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL--AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWN--AQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSV-LQNGTVILISSWLDYERHQRYKVPVFVTD-GL--YEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFR 1618
I EN+P+ V + N H + + SGP+ F I +Q + ++ A + D E I L + +E NL+ + VL VN+ PQF + VSE S G+ + ATD D + E+ ++ Y L + + K F++ + +++ LD E Q ++ + A N + +E V + + D ND PP F ++ + E P + + + A D D + Y N L++ F + +Q G I +S LD E Y + + D GL + + + +ED ND P + EN G I +I +D D + G + L GK+K L+ D +R+ T+FDRE + + ++ D S S + + +LD NDNP R
Sbjct: 3343 IPENKPVGTFVFQAHAADKDSPKNAIIHYAFL--PSGPDRHFFIMNQSNGTISSAVSFDYEERRI-YTLQIKAKNPDSSMESYANLY------------VHVLGVNEFYPQFLQPVFHFDVSETS-AVGTRVGAVQATDKD-SGEDGRVYYLLVGSSNDKGFRIDTNTG---LIYVARHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGE-ISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFT-----------YQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVED----SGKPKQKSQHLLTITVLDQNDNPSTTR 3758
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0304899) HSP 1 Score: 181.03 bits (458), Expect = 1.845e-45 Identity = 208/723 (28.77%), Postives = 324/723 (44.81%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESI----CINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGT-VILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKD---DSQT----NGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEH---DFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLT-PFEFSVRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPNDDTV--MITVNGT----LYITKPLDRE-TKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKD 2515
FSID S +++ K +D ES+ + R S +L+VN V+D NDN P+F + + V E + G +I A D+D NA+I Y ++E +F L +D R ++ + LD E Q + ++ A + + +V + V D NDN P FN + V E+ P + + + A DPD S L +++ T N + QNG +I I+ LDY++ +R+ + V TD G + + + + D N+ +P P V E++ G + V TD D ++Q N + I + +P FS++ T I T DRE +S + + DG N S L+ + + + + D NDN P F+ Y A + E+ +GT +++V A D D GLNG+I Y L + F ID T+G I +DRE + L AVD GS PL+S+V + I ++DVND+ P + V EN +P + +G++ D D G NA V +S +D ++T G+ L LD E T+ R L VR L ++ + I V DVNDN P L R + I + P I ++ A D D + KL Y IL N + + NS++G L L L+ + ++VSV D
Sbjct: 632 FSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVN----------------VIDANDNAPRFYTSQFQESVLE-NVPVGYNIIRVQAYDSDEG-ANAEITYSISERDDNFPLAVDP-RTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEI--TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDP---FSINP------QTGAIVTNAPLDRETTSGYLLTVTAKDGGNPS----LSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPEN-SPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPL----RNDAHIEILVTDVNDNAPVL---RDFQVIFNNFRD-----------HFPSGEIGRIPAFDAD--VSDKLHYRILSGNN--ANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSD 1297 HSP 2 Score: 176.022 bits (445), Expect = 7.720e-44 Identity = 193/682 (28.30%), Postives = 298/682 (43.70%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESICINREL--SSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSE-----ASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS---PQLIQNPSVIE--VMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF-------SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVREN-LAPATIGQLQYEDSDIGRNADVVF---SKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQ-SP-GYVITQLIAVDDDDATNTKLTYHIL 2392
F ID +S V++ ++D E+ L ++D +S Q + A V++ VLD NDN PQFS++ V E +HI ATD D NA I Y + + Q +D + L+ LD E+ Y + IRA + + N + + V D NDN PRF +S F V EN P I ++ A D D + + ++ L + G V I LD E R+ V DG +S +V D + P NP E V E+ G + V TD D+ + ++ E T R F+++S + ++T I + +EK ++V S G + +A +H + I D N+ P F + Y A V E+ P+GT +L V+A D D G+N +I YSL + F I+ TG I P+DRE Y L + A D G+ L+ + + I V DVNDN+P +P ++ S+ E+ L ++ Q+ D D+G N + + + + V+ +GT+ K LDRE+ L D G + S+ EV IR+ DVND+ P AS I++ V + SP G V+ ++ A D D+ N + Y I+
Sbjct: 521 FRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSE-----------RRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHI---RATDADQG-NNAAIRYAIIGGNTQSQFSIDSMSGD-VSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKP-LDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAF--NPKYYEANVGEDQPPGTPVTTVTATDPDE---DSRLHYEITTGNTRGRFAITSQNGRGLIT--IAQSLDYKQEKRFLLTVAATDSGGRSDTATVH--------INITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKG-SPPLSSTVEVQIRLEDVNDSPPTF----------------ASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSII 1153 HSP 3 Score: 160.999 bits (406), Expect = 2.611e-39 Identity = 196/746 (26.27%), Postives = 325/746 (43.57%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQ--------RQPYLFLLNDLDAENQTHYLIKIRAWN---AQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARS---MIFQLIANDPD--STSVLRFDLYQTANNELRKLFSV-LQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTK-----TAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLE--HDFSLFQIDSTTG--VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPNDDTV-------MITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREI-DDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
F +D ++ V+T + ++D E + ++ + ++ S ++++VLD ND+ P F ++ E + E + GS + ATD DI +NA+IEYG+ L DQ+ R + + LD E Y + + A + AQ ++ +V + V D NDN P+F+ ++V V E+ + + + A D D + + +R Y + FS+ +G V L+ LDYE + Y++ + DG +RS L+ + D +P+ + V+EN G I +V D D E + +S+S + L D RT DRE+ + + ++ DG + +SS I VQ D NDN P F Y A+V E+ P GT + V A D D+ + ++HY + + F I S G +IT+ +D + ++ + L + A DSG ++V +NIT D N+ +P P+ SV E+ AP T+ + DSD+G NA + +S N++++ ++N G + PLDRET + L V +D G N + +V I V DVNDN P +P I +DA G + Q+ A D D N ++ Y +L + F + T+G + +K L + + + D GSPPL
Sbjct: 407 FKVDSRTGVVTTSASLDRELMDVH------------YFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGA-TVGSTVITLRATDQDIG-KNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIR---YAIIGGNTQSQFSIDSMSGDVSLVKP-LDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSD------------EGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSA--SSSVVITVQ--DVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINIT--DANNFAPIFENAPYSASVFED-APVGTTVLVVSATDSDVGVNAQITYSL---NEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGG-NPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALV---------------GTSVIQVAASDPDVGLNGRIKY-LLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPL 1093 HSP 4 Score: 128.257 bits (321), Expect = 2.708e-29 Identity = 153/584 (26.20%), Postives = 237/584 (40.58%), Query Frame = 2
Query: 926 VDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRF------DLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS-------PQLIQNPSVIEVMENSGKGL---VIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP--FEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYIT--KPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLP--NTLPS-QIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFIT----NKPA 2578
V D ND+ P F + F ++E S + L A D D + + + D A ++ +F + VI S LD E Y + V D L A+S + PQ + ++V E+ G + + TD D N + + +FS+ S ++ D+ D E +V+ DG + S +++ + V ++D NDN P+F SQ+ V EN P+G I++V AYD D+G N +I YS+ + +F L +D TG + P+DRE + + + A D G P ++S + ITV DVNDN P P +E +V E+ P T + + D D + + + NG IT + LD + + R L V D +G R + V I + D N+ P N A S S+ G + + A D D N ++TY + N L S FS N TG + + PL Y + V+ KD G+P L D + +T N PA
Sbjct: 454 VLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAAD-LASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGN-NAAIRYAIIGGNTQSQFSIDS------MSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSR----SNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPL-AVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPA-FNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATD---SGGRSDTATVHINITDANNFAPIFEN--------------APYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPA 1006
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0300578) HSP 1 Score: 181.03 bits (458), Expect = 1.845e-45 Identity = 208/723 (28.77%), Postives = 324/723 (44.81%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESI----CINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGT-VILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKD---DSQT----NGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEH---DFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLT-PFEFSVRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPNDDTV--MITVNGT----LYITKPLDRE-TKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKD 2515
FSID S +++ K +D ES+ + R S +L+VN V+D NDN P+F + + V E + G +I A D+D NA+I Y ++E +F L +D R ++ + LD E Q + ++ A + + +V + V D NDN P FN + V E+ P + + + A DPD S L +++ T N + QNG +I I+ LDY++ +R+ + V TD G + + + + D N+ +P P V E++ G + V TD D ++Q N + I + +P FS++ T I T DRE +S + + DG N S L+ + + + + D NDN P F+ Y A + E+ +GT +++V A D D GLNG+I Y L + F ID T+G I +DRE + L AVD GS PL+S+V + I ++DVND+ P + V EN +P + +G++ D D G NA V +S +D ++T G+ L LD E T+ R L VR L ++ + I V DVNDN P L R + I + P I ++ A D D + KL Y IL N + + NS++G L L L+ + ++VSV D
Sbjct: 632 FSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVN----------------VIDANDNAPRFYTSQFQESVLE-NVPVGYNIIRVQAYDSDEG-ANAEITYSISERDDNFPLAVDP-RTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEI--TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDP---FSINP------QTGAIVTNAPLDRETTSGYLLTVTAKDGGNPS----LSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPEN-SPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPL----RNDAHIEILVTDVNDNAPVL---RDFQVIFNNFRD-----------HFPSGEIGRIPAFDAD--VSDKLHYRILSGNN--ANLLRLNSSSGGLVLSPQLNTNVPKFATMEVSVSD 1297 HSP 2 Score: 176.022 bits (445), Expect = 7.720e-44 Identity = 193/682 (28.30%), Postives = 298/682 (43.70%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESICINREL--SSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSE-----ASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS---PQLIQNPSVIE--VMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF-------SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVREN-LAPATIGQLQYEDSDIGRNADVVF---SKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQ-SP-GYVITQLIAVDDDDATNTKLTYHIL 2392
F ID +S V++ ++D E+ L ++D +S Q + A V++ VLD NDN PQFS++ V E +HI ATD D NA I Y + + Q +D + L+ LD E+ Y + IRA + + N + + V D NDN PRF +S F V EN P I ++ A D D + + ++ L + G V I LD E R+ V DG +S +V D + P NP E V E+ G + V TD D+ + ++ E T R F+++S + ++T I + +EK ++V S G + +A +H + I D N+ P F + Y A V E+ P+GT +L V+A D D G+N +I YSL + F I+ TG I P+DRE Y L + A D G+ L+ + + I V DVNDN+P +P ++ S+ E+ L ++ Q+ D D+G N + + + + V+ +GT+ K LDRE+ L D G + S+ EV IR+ DVND+ P AS I++ V + SP G V+ ++ A D D+ N + Y I+
Sbjct: 521 FRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSE-----------RRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHI---RATDADQG-NNAAIRYAIIGGNTQSQFSIDSMSGD-VSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWVQTIKP-LDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAF--NPKYYEANVGEDQPPGTPVTTVTATDPDE---DSRLHYEITTGNTRGRFAITSQNGRGLIT--IAQSLDYKQEKRFLLTVAATDSGGRSDTATVH--------INITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKG-SPPLSSTVEVQIRLEDVNDSPPTF----------------ASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSII 1153 HSP 3 Score: 160.999 bits (406), Expect = 2.611e-39 Identity = 196/746 (26.27%), Postives = 325/746 (43.57%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQ--------RQPYLFLLNDLDAENQTHYLIKIRAWN---AQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARS---MIFQLIANDPD--STSVLRFDLYQTANNELRKLFSV-LQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTK-----TAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLE--HDFSLFQIDSTTG--VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPNDDTV-------MITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREI-DDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
F +D ++ V+T + ++D E + ++ + ++ S ++++VLD ND+ P F ++ E + E + GS + ATD DI +NA+IEYG+ L DQ+ R + + LD E Y + + A + AQ ++ +V + V D NDN P+F+ ++V V E+ + + + A D D + + +R Y + FS+ +G V L+ LDYE + Y++ + DG +RS L+ + D +P+ + V+EN G I +V D D E + +S+S + L D RT DRE+ + + ++ DG + +SS I VQ D NDN P F Y A+V E+ P GT + V A D D+ + ++HY + + F I S G +IT+ +D + ++ + L + A DSG ++V +NIT D N+ +P P+ SV E+ AP T+ + DSD+G NA + +S N++++ ++N G + PLDRET + L V +D G N + +V I V DVNDN P +P I +DA G + Q+ A D D N ++ Y +L + F + T+G + +K L + + + D GSPPL
Sbjct: 407 FKVDSRTGVVTTSASLDRELMDVH------------YFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGA-TVGSTVITLRATDQDIG-KNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIR---YAIIGGNTQSQFSIDSMSGDVSLVKP-LDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSD------------EGANAEITYSISERDDNFPLAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSA--SSSVVITVQ--DVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSDTATVHINIT--DANNFAPIFENAPYSASVFED-APVGTTVLVVSATDSDVGVNAQITYSL---NEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGG-NPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALV---------------GTSVIQVAASDPDVGLNGRIKY-LLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPL 1093 HSP 4 Score: 128.257 bits (321), Expect = 2.708e-29 Identity = 153/584 (26.20%), Postives = 237/584 (40.58%), Query Frame = 2
Query: 926 VDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRF------DLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS-------PQLIQNPSVIEVMENSGKGL---VIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP--FEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYIT--KPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLP--NTLPS-QIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFIT----NKPA 2578
V D ND+ P F + F ++E S + L A D D + + + D A ++ +F + VI S LD E Y + V D L A+S + PQ + ++V E+ G + + TD D N + + +FS+ S ++ D+ D E +V+ DG + S +++ + V ++D NDN P+F SQ+ V EN P+G I++V AYD D+G N +I YS+ + +F L +D TG + P+DRE + + + A D G P ++S + ITV DVNDN P P +E +V E+ P T + + D D + + + NG IT + LD + + R L V D +G R + V I + D N+ P N A S S+ G + + A D D N ++TY + N L S FS N TG + + PL Y + V+ KD G+P L D + +T N PA
Sbjct: 454 VLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAAD-LASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGN-NAAIRYAIIGGNTQSQFSIDS------MSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSR----SNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPL-AVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPA-FNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATD---SGGRSDTATVHINITDANNFAPIFEN--------------APYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPA 1006
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 233.032 bits (593), Expect = 1.942e-62 Identity = 224/793 (28.25%), Postives = 367/793 (46.28%), Query Frame = 2
Query: 224 LKTLFLFLTAVRC---SETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGS--LIYKL---SGPNCCFSI-DQKSSVLTIAKNIDLESICINRELS-SDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYE-ARSXXXXXXXXXXXXSPQL----IQNPSVIEVM--ENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
L+ FL T V C T +E + Y I+E + ++G I D+ +N + L+Y+L +G + + T + ID E +C S+CS E+ V + N +++++I V D NDN P F I + E + S + +ATD D P N+ +Y L +F L + + ++ P L + +LD E + Y++K++ + + ++ + + + V D NDN P F S V + EN+P + + QL A D D + + +++ + R+LF++ +I + LD E +K+ V +DG AR+ + + V D ND +P + I +P+ VM E I + V+DK D+ NGK+IC E P F L + + + Y + T D E + + ++ SD S N + + V++ D NDNPP F Q V EN + ++A D D G N +I Y L + S F +D TGV+T DRE +E + + A D+G+ L S + +T+ D NDNSP F+F V ENL +T+G + D+D G NA V S N++ ++ +G + DRE + + VR DNG + S+ +V I VIDVNDN P +I P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + IG + + V++ D G P
Sbjct: 3 LRDFFLLATLVACFWLDPTIAQELI--YPIREELQENVLIGNIPKDLNISHMNSATGATSNLVYRLVSKAGDTPLLRVMSNTGEIFTTSNRIDREKLCPGPSFEDSECS-----FEIEVVILPN-DYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFAIPSATDPDTGP-NSVHKYELLNGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKVKVEDGGNPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPENSPVGTSVVQLQATDADVGANAEIKYMFGAQVSPATRRLFALNTTTGLITVQRPLDREETAIHKLTVLASDGSSSPARATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDK-DTDVNGKVICFIEKDVP---FHLKAVYDNQ---YLLETSALLDYEGTKEYIFKIVASDSGKPSLN----QTALVRVRLEDENDNPPIFTQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVRLSILNDNENFILDPDSGVIKSNVSFDREQQSSYTFDVRAVDNG-SPPCSSAAKVTINVIDVNDNTPIVIYP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVSGNV--RSLFRIDPVTGNITLEEKPTIADIGLHRLVVNISDLGYP 760
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Match: CR847522.1 (pep chromosome:GRCz11:CHR_ALT_CTG6_1_1:4874141:4879379:1 gene:ENSDARG00000111493.1 transcript:ENSDART00000185190.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR847522.1) HSP 1 Score: 233.417 bits (594), Expect = 1.956e-62 Identity = 226/806 (28.04%), Postives = 373/806 (46.28%), Query Frame = 2
Query: 224 LKTLFLFLTAVRC---SETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGS--LIYKL---SGPNCCFSI-DQKSSVLTIAKNIDLESICINRELS-SDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYE-ARSXXXXXXXXXXXXSPQL----IQNPSVIEVM--ENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDE-KMFYLFI 2563
L+ FL T V C T +E + Y I+E + ++G I D+ +N + L+Y+L +G + + T + ID E +C S+CS E+ V + N +++++I V D NDN P F I + E + S + +ATD D P N+ +Y L +F L + + ++ P L + +LD E + Y++K++ + + ++ + + + V D NDN P F S V + EN+P + + QL A D D + + +++ + R+LF++ +I + LD E +K+ V +DG AR+ + + V D ND +P + I +P+ VM E I + V+DK D+ NGK+IC E P F L + + + Y + T D E + + ++ SD S N + + V++ D NDNPP F Q V EN + ++A D D G N +I Y L + S F +D TGV+T DRE +E + + A D+G+ L S + +T+ D NDNSP F+F V ENL +T+G + D+D G NA V S N++ ++ +G + DRE + + VR DNG + S+ +V I VIDVNDN P +I P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + IG + + V++ D G P + + +LF+
Sbjct: 3 LRDFFLLATLVACFWLDPTIAQELI--YPIREELQENVLIGNIPKDLNISHMNSATGATSNLVYRLVSKAGDTPLLRVMSNTGEIFTTSNRIDREKLCPGPSFEDSECS-----FEIEVVILPN-DYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFAIPSATDPDTGP-NSVHKYELLNGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKVKVEDGGNPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPENSPVGTSVVQLQATDADVGANAEIKYMFGAQVSPATRRLFALNTTTGLITVQRPLDREETAIHKLTVLASDGSSSPARATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDK-DTDVNGKVICFIEKDVP---FHLKAVYDNQ---YLLETSALLDYEGTKEYIFKIVASDSGKPSLN----QTALVRVRLEDENDNPPIFTQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVRLSILNDNENFILDPDSGVIKSNVSFDREQQSSYTFDVRAVDNG-SPPCSSAAKVTINVIDVNDNTPIVIYP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVSGNV--RSLFRIDPVTGNITLEEKPTIADIGLHRLVVNISDLGYPKSLHTLVLVFLFV 773
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 233.032 bits (593), Expect = 2.129e-62 Identity = 226/806 (28.04%), Postives = 373/806 (46.28%), Query Frame = 2
Query: 224 LKTLFLFLTAVRC---SETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGS--LIYKL---SGPNCCFSI-DQKSSVLTIAKNIDLESICINRELS-SDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYE-ARSXXXXXXXXXXXXSPQL----IQNPSVIEVM--ENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDE-KMFYLFI 2563
L+ FL T V C T +E + Y I+E + ++G I D+ +N + L+Y+L +G + + T + ID E +C S+CS E+ V + N +++++I V D NDN P F I + E + S + +ATD D P N+ +Y L +F L + + ++ P L + +LD E + Y++K++ + + ++ + + + V D NDN P F S V + EN+P + + QL A D D + + +++ + R+LF++ +I + LD E +K+ V +DG AR+ + + V D ND +P + I +P+ VM E I + V+DK D+ NGK+IC E P F L + + + Y + T D E + + ++ SD S N + + V++ D NDNPP F Q V EN + ++A D D G N +I Y L + S F +D TGV+T DRE +E + + A D+G+ L S + +T+ D NDNSP F+F V ENL +T+G + D+D G NA V S N++ ++ +G + DRE + + VR DNG + S+ +V I VIDVNDN P +I P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + IG + + V++ D G P + + +LF+
Sbjct: 3 LRDFFLLATLVACFWLDPTIAQELI--YPIREELQENVLIGNIPKDLNISHMNSATGATSNLVYRLVSKAGDTPLLRVMSNTGEIFTTSNRIDREKLCPGPSFEDSECS-----FEIEVVILPN-DYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFAIPSATDPDTGP-NSVHKYELLNGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKVKVEDGGNPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPENSPVGTSVVQLQATDADVGANAEIKYMFGAQVSPATRRLFALNTTTGLITVQRPLDREETAIHKLTVLASDGSSSPARATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDK-DTDVNGKVICFIEKDVP---FHLKAVYDNQ---YLLETSALLDYEGTKEYIFKIVASDSGKPSLN----QTALVRVRLEDENDNPPIFTQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVRLSILNDNENFILDPDSGVIKSNVSFDREQQSSYTFDVRAVDNG-SPPCSSAAKVTINVIDVNDNTPIVIYP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVSGNV--RSLFRIDPVTGNITLEEKPTIADIGLHRLVVNISDLGYPKSLHTLVLVFLFV 773
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 233.032 bits (593), Expect = 2.129e-62 Identity = 226/806 (28.04%), Postives = 373/806 (46.28%), Query Frame = 2
Query: 224 LKTLFLFLTAVRC---SETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGS--LIYKL---SGPNCCFSI-DQKSSVLTIAKNIDLESICINRELS-SDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYE-ARSXXXXXXXXXXXXSPQL----IQNPSVIEVM--ENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDE-KMFYLFI 2563
L+ FL T V C T +E + Y I+E + ++G I D+ +N + L+Y+L +G + + T + ID E +C S+CS E+ V + N +++++I V D NDN P F I + E + S + +ATD D P N+ +Y L +F L + + ++ P L + +LD E + Y++K++ + + ++ + + + V D NDN P F S V + EN+P + + QL A D D + + +++ + R+LF++ +I + LD E +K+ V +DG AR+ + + V D ND +P + I +P+ VM E I + V+DK D+ NGK+IC E P F L + + + Y + T D E + + ++ SD S N + + V++ D NDNPP F Q V EN + ++A D D G N +I Y L + S F +D TGV+T DRE +E + + A D+G+ L S + +T+ D NDNSP F+F V ENL +T+G + D+D G NA V S N++ ++ +G + DRE + + VR DNG + S+ +V I VIDVNDN P +I P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + IG + + V++ D G P + + +LF+
Sbjct: 3 LRDFFLLATLVACFWLDPTIAQELI--YPIREELQENVLIGNIPKDLNISHMNSATGATSNLVYRLVSKAGDTPLLRVMSNTGEIFTTSNRIDREKLCPGPSFEDSECS-----FEIEVVILPN-DYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFAIPSATDPDTGP-NSVHKYELLNGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKVKVEDGGNPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPENSPVGTSVVQLQATDADVGANAEIKYMFGAQVSPATRRLFALNTTTGLITVQRPLDREETAIHKLTVLASDGSSSPARATITINVTDVNDNAPNIDLRYIISPTNGTVMLSEKDPINTKIALITVSDK-DTDVNGKVICFIEKDVP---FHLKAVYDNQ---YLLETSALLDYEGTKEYIFKIVASDSGKPSLN----QTALVRVRLEDENDNPPIFTQPVIELAVMENNLRDMFLTTISATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFLFTVTARDNGTRALQSQAAVIVTILDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVRLSILNDNENFILDPDSGVIKSNVSFDREQQSSYTFDVRAVDNG-SPPCSSAAKVTINVIDVNDNTPIVIYP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVSGNV--RSLFRIDPVTGNITLEEKPTIADIGLHRLVVNISDLGYPKSLHTLVLVFLFV 773
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 226.868 bits (577), Expect = 1.664e-60 Identity = 219/779 (28.11%), Postives = 366/779 (46.98%), Query Frame = 2
Query: 296 YLIQENEPIDRMVGTIATDIE-GLGINLEFHGSLIYK---LSGPNCCFSIDQKSS-VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-LYEARSXXXXXXXXXXXXSPQL-------IQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDE-KMFYLFI 2563
Y ++E +P + +G + D+ L +++ +L +K +G ++ + +LT A ID E +C S + + + E+ V + + ++ +V++R + D+NDN P F I + E + S + +A D DI Q Y L + F L + + + P L + LD E + +++KI+ + + + + + + V D NDN P F S V V EN P + + L A D D S + + F + ++ F++ +I + LD E + +K+ V +DG +R+ + V V D ND P + + N +V+ + EN+ I + VTD+ DS NGK+ C T+ + F L N + L + T D E + + ++ ++ SD S L +S + ++I D NDN P F Q + + EN GT ++K++A D D G N I YSL D F IDS +G+++V +DRE +E Y + A D+G+ PL S+V + + V D NDNSP P + F V ENL T+G + D+D G NA V S D+ ++ G + DRE + + V+ D GL + S +V I V+DVNDN+P + P D S SPG V+T++ A+D+D N +L Y I+ + +F+ + TTG ++L + + G + + V VKD G P + + +LF+
Sbjct: 28 YTVKEEQPENVRIGNLRKDLNLNLDPDIKLSSALQFKPVYKTGDVPLVKVEASTGEILTTANRIDREKLC-----SGVFNEKRCYYEIEVAVLPD-EIFRLVKIRFLIEDINDNAPLFQSTVINISIPENT-AINSRYPVPSAFDPDIGINGIQ-HYELVKSVSEFGLDIIETPEGDKWPQLIVQQSLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTHLHATDADLGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNPVHKLIVLASDGSSTPSRATVIVNVTDINDNVPSIDTRYIMNLVNGTVL-LSENAPLNTKIALITVTDR-DSDLNGKVTC---YTDHDVPFRLKPVFNDQFL---LETAAPLDYETTREYAIRIVASD----SGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLIKISATDADSGSNALIIYSLGPDAPDGFNIDSRSGILSVVKRLDREKQEKYSFTVIARDNGTTPLQSNVTVKLIVQDQNDNSPAFTHPEYNFYVPENLPLYGTVGLITVTDADAGDNAVVTLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDAGL-MQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDLVPS-----------NTSPGSVVTRVFAIDNDTGMNAELQYSIIGGSL--RGLFTIDKTTGNITLQEKIVAADQGLHRLVVKVKDLGQPESLHAIALVHLFV 772 HSP 2 Score: 103.605 bits (257), Expect = 7.575e-22 Identity = 102/349 (29.23%), Postives = 156/349 (44.70%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQID---STTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFS---KTWPNDDT--VMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDA-TNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F+ + + EN I + +A+D D G+NG HY L S F +D + G + VQ +DRE K+ + + I D G+ P +S+ L +TV DVNDN P + E +V EN T + L D+D+G NA + FS + P+ + + G + + +PLDRE H L V D R + V + V D+NDN P I+ R + + + T + +P LI V D D+ N K+T + + +P ++ + L PL + Y I++ DSG PPL M + I ++
Sbjct: 125 IRFLIEDINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQSLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTHLHATDADLGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNPVHKLIVLASDGSSTPSRAT---VIVNVTDINDNVPS-IDTRYIMNLVNGTVLLSE--------NAPLNTKIALITVTDRDSDLNGKVTCYT--DHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIRIVASDSGKPPLNTSAMVLIKIKDE 459
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Match: vapa (VAMP associated protein A [Source:Xenbase;Acc:XB-GENE-990155]) HSP 1 Score: 236.884 bits (603), Expect = 1.598e-63 Identity = 224/804 (27.86%), Postives = 368/804 (45.77%), Query Frame = 2
Query: 224 LKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGS--LIYKL---SGPNCCFSIDQKSS-VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP-PLIDEKMFYLFI 2563
L+ +L + C ++ I + ++ Y I+E P + +G I D+ IN S L+Y+L +G + + + + T + ID E +C SS+ + EL V + N +++++I V D NDN P F I + E + S + +A D D Q Y L F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F S V + EN P + + QL A D D S + +++ + ++LF++ +I + LD E +K+ V TDG AR+ + + V D ND P + I +P + + E I + V+DKD + N K+IC E P F L + + + Y + T + D E + S ++ +D S N + + V++ D NDNPP F Q V+EN G + V+A D D G N I Y L + S F +D TGV+T DRE +E + + A D+G+ PL S + +TV D NDNSP F+F V ENL +T+G + DSD G N V S N++ V+ +G + DRE + + V+ D G R S+ +V I ++D NDN P +I+P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ S +G + + V++ D G P PL + +L++
Sbjct: 3 LRDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGSSTSLVYRLVSKAGDSPLVKVSSSTGEIFTTSTRIDREKLCAG---SSNSDENECFFELEVVILPN-DFFRLIKIKIIVKDTNDNAPMFPSTVINISIPENT-LINSRFPIPSAVDPDTGFNGVQ-HYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNKPVFKESQVEVHIPENAPIGTSVVQLHATDADIGSNAEIKYIFGAQVTSATKRLFALNNTTGLITVQRPLDREETAVHKLTVLATDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPINTKIALITVSDKD-TDVNSKVICFIEREVP---FHLKAVYDNQ---YLLETSSLLDYEGIKEFSFKIVAADTGKPSLN----QTALVRVELEDENDNPPIFSQPVIELSVSENNRRGLYLTTVSASDEDSGKNSDIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITATDSDAGENKAVTLSILNDNENFVLDPYSGLIKSNVSFDREQQSSYTFDVKAVDGG-QPPRSSTAKVTINIMDANDNSPVVISP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDTDTGMNAELKYTIVSGNN--KGLFRIDPVTGNITLEEKPSAADVGLHRLVVNISDLGYPKPLHTLVLVFLYV 774
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Match: ENSXETT00000047804.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 218.009 bits (554), Expect = 2.315e-57 Identity = 213/809 (26.33%), Postives = 368/809 (45.49%), Query Frame = 2
Query: 212 KMDILKTLFLFLTAVRC--SETGIKECVLKYLIQENEPIDRMVGTIATDIE-----GLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF-SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSL-DKPLSHHYIGHYPIKVSVKDSGSP-PLIDEKMFYLFI 2563
+MD+L +L + C E+G +E Y+++E P + ++G + D+ L L+F L+YK + + T + ID E +C S + + E+ V + + ++ +V++R + D+NDN P F I + E + S + +A D D+ Q Y L + F L + + + P L + LD E + Y++KI+ + + + + + + V D NDN P F V + E+ + + QL A D D S + + F N ++ F++ N +I + LD E +K+ V +DG +R+ + + + D ND P + I NP +++ E + I + VTDKD + NGK+ C T+ + F L + + L + T D E + + ++ ++ SD S L S + ++I D NDN P F EN P GT + K++A D D G N ++ Y L + ++F +D TG++T +DRE ++ Y + A D+G+ L ++ + ++V D NDNSP + F V ENL T+G + D+D G NA V S D+ ++ + G + DRE + + +V+ D G + ++ S+ +V I V DVNDNKP + P D + SPG V+ ++ A+D+D N L Y I+ N+ +F+ +G ++L +K L+ + Y + + V DSG P P +LF+
Sbjct: 20 EMDLLSGTYLLAVLIACIVFESGAQEK--NYIVREELPENVLIGNLLKDLNLTLDPDLSTPLQFK--LVYKTGDVPLIRVEENTGEIFTTSNRIDREKLC-----SGIFTENKCFYEVEVAVLPD-EVFRLVKIRFLIEDINDNSPLFPSTVINISIPENT-AVNSRYSVPSAIDPDVGVNGIQ-HYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESPYHKLTVLASDGSSTPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKD-ADLNGKVTC---FTDHDVPFRLKPVFDNQFL---LETAAPLDYESTREYAIKIVASD----SGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQDRYTFTVIAKDNGNPSLQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAVVTLSLVNARDNFIIDPLTGVIRPNITFDREQQGSYTFQVKALDKG-SPQKSSTVKVTIFVEDVNDNKPVFVIPSNNYSYD-----------LVQTSTSPGSVVARVYAIDNDTGINADLRYSIIGGNS--RGLFAIGERSGNITLKEKLLAGDHGVLYKLVIKVNDSGKPEPFHTIAFVHLFV 791 HSP 2 Score: 98.9821 bits (245), Expect = 2.791e-20 Identity = 103/354 (29.10%), Postives = 153/354 (43.22%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPAT-IGQLQYEDSDIGRNADV--VFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPR-----LINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDA-TNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F + + EN + + +A D D G+NG HY L ++ F L I++ G + VQ +DRE K+ Y + I D G+ +S+ L +TV DVNDN P E ++ E+ A T + QL D+D+G NA + F N ++ G + + +PLDRE H L V D R + V I + D+NDN P +INP + ++ +S ++P LI V D DA N K+T + +P ++ L PL + Y IK+ DSG PPL M + I ++
Sbjct: 143 IRFLIEDINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGVNGIQHYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESPYHKLTVLASDGSSTPSRAT---VTINITDINDNIPSIDTRYIINP-------------VNGTVQLS-EKAPLNTKIALITVTDKDADLNGKVT--CFTDHDVPFRLKPVFDNQFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDE 477
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Match: ENSXETT00000047801.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 217.624 bits (553), Expect = 2.686e-57 Identity = 213/809 (26.33%), Postives = 368/809 (45.49%), Query Frame = 2
Query: 212 KMDILKTLFLFLTAVRC--SETGIKECVLKYLIQENEPIDRMVGTIATDI-----EGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF-SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSL-DKPLSHHYIGHYPIKVSVKDSGSP-PLIDEKMFYLFI 2563
+MD+L +L + C E+G +E Y+++E P + ++G + D+ L L+F L+YK + + T + ID E +C S + + E+ V + + ++ +V++R + D+NDN P F I + E + S + +A D D+ Q Y L + F L + + + P L + LD E + Y++KI+ + + + + + + V D NDN P F V + E+ + + QL A D D S + + F N ++ F++ N +I + LD E +K+ V +DG +R+ + + + D ND P + I NP +++ E + I + VTDKD + NGK+ C T+ + F L + + L + T D E + + ++ ++ SD S L S + ++I D NDN P F EN P GT + K++A D D G N ++ Y L + ++F +D TG++T +DRE ++ Y + A D+G+ L ++ + ++V D NDNSP + F V ENL T+G + D+D G NA V S D+ ++ + G + DRE + + +V+ D G + ++ S+ +V I V DVNDNKP + P D + SPG V+ ++ A+D+D N L Y I+ N+ +F+ +G ++L +K L+ + Y + + V DSG P P +LF+
Sbjct: 20 EMDLLSGTYLLAVLIACIVFESGAQEK--NYIVREELPENVLIGNLLKDLNLTLDPDLSTPLQF--KLVYKTGDVPLIRVEENTGEIFTTSNRIDREKLC-----SGIFTENKCFYEVEVAVLPD-EVFRLVKIRFLIEDINDNSPLFPSTVINISIPENT-AVNSRYSVPSAIDPDVGVNGIQ-HYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESPYHKLTVLASDGSSTPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKD-ADLNGKVTC---FTDHDVPFRLKPVFDNQFL---LETAAPLDYESTREYAIKIVASD----SGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQDRYTFTVIAKDNGNPSLQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAVVTLSLVNARDNFIIDPLTGVIRPNITFDREQQGSYTFQVKALDKG-SPQKSSTVKVTIFVEDVNDNKPVFVIPSNNYSYD-----------LVQTSTSPGSVVARVYAIDNDTGINADLRYSIIGGNS--RGLFAIGERSGNITLKEKLLAGDHGVLYKLVIKVNDSGKPEPFHTIAFVHLFV 791 HSP 2 Score: 98.9821 bits (245), Expect = 3.032e-20 Identity = 103/354 (29.10%), Postives = 153/354 (43.22%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPAT-IGQLQYEDSDIGRNADV--VFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPR-----LINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDA-TNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F + + EN + + +A D D G+NG HY L ++ F L I++ G + VQ +DRE K+ Y + I D G+ +S+ L +TV DVNDN P E ++ E+ A T + QL D+D+G NA + F N ++ G + + +PLDRE H L V D R + V I + D+NDN P +INP + ++ +S ++P LI V D DA N K+T + +P ++ L PL + Y IK+ DSG PPL M + I ++
Sbjct: 143 IRFLIEDINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGVNGIQHYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESPYHKLTVLASDGSSTPSRAT---VTINITDINDNIPSIDTRYIINP-------------VNGTVQLS-EKAPLNTKIALITVTDKDADLNGKVT--CFTDHDVPFRLKPVFDNQFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDE 477
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Match: ENSXETT00000047798.1 (protocadherin 11 X-linked [Source:NCBI gene;Acc:100493938]) HSP 1 Score: 217.238 bits (552), Expect = 4.030e-57 Identity = 213/808 (26.36%), Postives = 367/808 (45.42%), Query Frame = 2
Query: 215 MDILKTLFLFLTAVRC--SETGIKECVLKYLIQENEPIDRMVGTIATDI-----EGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF-SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSL-DKPLSHHYIGHYPIKVSVKDSGSP-PLIDEKMFYLFI 2563
MD+L +L + C E+G +E Y+++E P + ++G + D+ L L+F L+YK + + T + ID E +C S + + E+ V + + ++ +V++R + D+NDN P F I + E + S + +A D D+ Q Y L + F L + + + P L + LD E + Y++KI+ + + + + + + V D NDN P F V + E+ + + QL A D D S + + F N ++ F++ N +I + LD E +K+ V +DG +R+ + + + D ND P + I NP +++ E + I + VTDKD + NGK+ C T+ + F L + + L + T D E + + ++ ++ SD S L S + ++I D NDN P F EN P GT + K++A D D G N ++ Y L + ++F +D TG++T +DRE ++ Y + A D+G+ L ++ + ++V D NDNSP + F V ENL T+G + D+D G NA V S D+ ++ + G + DRE + + +V+ D G + ++ S+ +V I V DVNDNKP + P D + SPG V+ ++ A+D+D N L Y I+ N+ +F+ +G ++L +K L+ + Y + + V DSG P P +LF+
Sbjct: 1 MDLLSGTYLLAVLIACIVFESGAQEK--NYIVREELPENVLIGNLLKDLNLTLDPDLSTPLQF--KLVYKTGDVPLIRVEENTGEIFTTSNRIDREKLC-----SGIFTENKCFYEVEVAVLPD-EVFRLVKIRFLIEDINDNSPLFPSTVINISIPENT-AVNSRYSVPSAIDPDVGVNGIQ-HYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESPYHKLTVLASDGSSTPSRATVTINITDINDNIPSIDTRYIINPVNGTVQLSEKAPLNTKIALITVTDKD-ADLNGKVTC---FTDHDVPFRLKPVFDNQFL---LETAAPLDYESTREYAIKIVASD----SGKPPLNQSAMLLIKIKDENDNAPVFTLPMIGLSFVENNPPGTELTKISATDADSGRNAELSYMLGPNAPTIFNLDRRTGILTAVRKLDREKQDRYTFTVIAKDNGNPSLQTNTTVTLSVLDQNDNSPSFTHNEYNFYVPENLPMYGTVGLITVTDADSGENAVVTLSLVNARDNFIIDPLTGVIRPNITFDREQQGSYTFQVKALDKG-SPQKSSTVKVTIFVEDVNDNKPVFVIPSNNYSYD-----------LVQTSTSPGSVVARVYAIDNDTGINADLRYSIIGGNS--RGLFAIGERSGNITLKEKLLAGDHGVLYKLVIKVNDSGKPEPFHTIAFVHLFV 771 HSP 2 Score: 98.9821 bits (245), Expect = 3.149e-20 Identity = 103/354 (29.10%), Postives = 153/354 (43.22%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPAT-IGQLQYEDSDIGRNADV--VFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPR-----LINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDA-TNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F + + EN + + +A D D G+NG HY L ++ F L I++ G + VQ +DRE K+ Y + I D G+ +S+ L +TV DVNDN P E ++ E+ A T + QL D+D+G NA + F N ++ G + + +PLDRE H L V D R + V I + D+NDN P +INP + ++ +S ++P LI V D DA N K+T + +P ++ L PL + Y IK+ DSG PPL M + I ++
Sbjct: 123 IRFLIEDINDNSPLFPSTVINISIPENTAVNSRYSVPSAIDPDVGVNGIQHYELLKGQNVFGLDVIETPEGDKWPQLIVQQSLDREQKDTYVMKIKVEDGGNPARSSTAILQVTVTDVNDNRPVFKEKDIEVNIPEDAAVGTSVTQLHATDADLGSNAKIHFYFGNQITNLAKRHFAIDNNTGLITVKEPLDREESPYHKLTVLASDGSSTPSRAT---VTINITDINDNIPSIDTRYIINP-------------VNGTVQLS-EKAPLNTKIALITVTDKDADLNGKVT--CFTDHDVPFRLKPVFDNQFLLETAAPLDYESTREYAIKIVASDSGKPPLNQSAMLLIKIKDE 457
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 216.083 bits (549), Expect = 9.110e-57 Identity = 218/802 (27.18%), Postives = 358/802 (44.64%), Query Frame = 2
Query: 290 LKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSS-VLTIAKNIDLESI--CINRELSSDCSSGQGHLEL---IVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTD------------IAPENAQIEYGLAEHHKSFQLCLDQ-QRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDL-YQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQ------------------VIVTDKDDSQTNGKMICEHETTEP-RLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS---LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSP-CLLTPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFI 2563
+ Y + E +P + ++G++A+D G H +YKL + +D K+ + T +ID ES+ C N E C LE + +L S V L + +I ++D+NDN P F+ I + E ++ G + ATD D + PE AQ +GL Q+ DQ ++QP L ++ LD E + Y + I+ + + + + + + D NDN P+F + + EN+P + Q+ AND D D + A++ +R+L + ++ +I + +D E K V D ++ + D + N VIE+ G GLV Q V V+D D+ N + C P +L+ +G + K Y ++T TA D E + ++ ++ D S N L+S+ ++ VQ+ D NDN P F QS EN I ++++V+A D D G N ++HYS+ D S +F I+ +G I V +DRE +EHY H+ AVD G L + + ITV D NDN P +L + FSV EN+ + +G + D+D G NA + S + + V+ GT+ + DRE + + R++ D G R G V I V+D NDN P ++ P + ++ PG + + A D D N +L Y I N P ++F + G ++L+K + + G + + V V D G P + + +I
Sbjct: 69 VAYRVPEEQPPNILIGSLASD---YGYPDSKH---LYKLELGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGEKC-----FLEFEVSMTDLMSPVPRL--LDGQIEIMDINDNTPNFNSPVITLSIPENTN-IGMLFPIPAATDRDSGVNGVSSYELIVGPE-AQDLFGL-------QVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTN----DNKPVIEI---RGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEG-VNAAVTCVVAGDVPFQLKQVSDTGSDSK-KKYFLQTTTALDYESVKEYTIEIVAVD----SGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVG-VTINVLDENDNAPVIVVPSNI------------SYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGN--PFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYI 820 HSP 2 Score: 104.375 bits (259), Expect = 7.316e-22 Identity = 136/577 (23.57%), Postives = 241/577 (41.77%), Query Frame = 2
Query: 176 SYNYKLIFQQSGKMDILKTLFLFLTAVRCSETGIKECVLKYLIQ--ENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAG-SHIFLETATDTDIA-PENAQIEYGL-------AEHHKSFQL------CLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GL--YEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRL-EFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKF--RQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLE--HDFSLFQIDSTTGVITVQGPVDRELKEHYKLH 1831
SY+ + Q G + L ++ + ++ K + Y + EN P+ V + + G+N E S +D+ + ++T+ ID E + G ++ A +V I++ D NDN P R +H+ G ++I + +T +A + + I+ G+ FQL D +++ +L LD E+ Y I+I A ++ + + ++ + V D NDN P F+ SL V+ EN ++ ++ A D DS + + R +FS+ + I +++ LD E+ + Y V D G+ + + + + V D ND P+ + N VMEN + +G V V D D G+ H + EP EF + +G T I + +FDRE S + L DG + +S + + +LD NDN P + + ++ GT + V A D+D G+N ++ YS+ + F LFQI G +T++ + +++HY LH
Sbjct: 253 SYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRLLHLDRSTGLITVQGPIDREDV------------GTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEI----RGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMENMPRLSPVGMVTVIDAD----KGENAHIHLSVEPESGEFVIQNG------TGTILSSISFDREHQSTYTFRLKAVDGGDPPR----SSYVGVTINVLDENDNAPVIVVPSNISYKYLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFELFQISHNNGEVTLEKAI---IRKHYGLH 796
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Match: Pcdh9 (protocadherin 9 [Source:MGI Symbol;Acc:MGI:1306801]) HSP 1 Score: 237.269 bits (604), Expect = 1.838e-64 Identity = 224/808 (27.72%), Postives = 364/808 (45.05%), Query Frame = 2
Query: 224 LKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEF--HGSLIYKLSGPNCCFSIDQKSS----VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPA 2578
L+ +L + C ++ I + ++ Y I+E P + +G I D+ IN SL+Y+L + + SS + T + ID E +C +S + EL V + N +++++I V D NDN P F I + E + S + +ATD D Q Y L F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F V + EN P + + QL A D D S + +R+ ++LF++ +I + LD E +KV V +DG AR+ + + V D ND P + I +P + + E I + V+DKD + NGK+IC E P F L + + + Y + T + D E + + S ++ SD S N + + V++ D NDNPP F Q V+EN G + ++A D D G N I Y L + S F +D TGV+T +RE +E + + A D+G+ PL S + +TV D NDNSP F+F V ENL +T+G + D D G N V S N++ V+ +G + DRE + + V+ D G R S+ +V I V+DVNDN P +I+P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + +G + + V++ D G P + + N A
Sbjct: 3 LRDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAG---ASYAEENECFFELEVVILPN-DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTL-INSRFPIPSATDPDTGFNGVQ-HYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKD-TDVNGKVICFIEREVP---FHLKAVYDNQ---YLLETSSLLDYEGTKEFSFKIVASDSGKPSLN----QTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGG-QPPRSSTAKVTINVMDVNDNSPVVISP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNN--KGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTA 778
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Match: Pcdh9 (protocadherin 9 [Source:MGI Symbol;Acc:MGI:1306801]) HSP 1 Score: 236.884 bits (603), Expect = 3.134e-63 Identity = 224/808 (27.72%), Postives = 364/808 (45.05%), Query Frame = 2
Query: 224 LKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEF--HGSLIYKLSGPNCCFSIDQKSS----VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPA 2578
L+ +L + C ++ I + ++ Y I+E P + +G I D+ IN SL+Y+L + + SS + T + ID E +C +S + EL V + N +++++I V D NDN P F I + E + S + +ATD D Q Y L F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F V + EN P + + QL A D D S + +R+ ++LF++ +I + LD E +KV V +DG AR+ + + V D ND P + I +P + + E I + V+DKD + NGK+IC E P F L + + + L + T + D E + + S ++ SD S L + + V++ D NDNPP F Q V+EN G + ++A D D G N I Y L + S F +D TGV+T +RE +E + + A D+G+ PL S + +TV D NDNSP F+F V ENL +T+G + D D G N V S N++ V+ +G + DRE + + V+ D G R S+ +V I V+DVNDN P +I+P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + +G + + V++ D G P + + N A
Sbjct: 3 LRDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAG---ASYAEENECFFELEVVILPN-DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFPIPSATDPDTGFNGVQ-HYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKD-TDVNGKVICFIEREVP---FHLKAVYDNQYL---LETSSLLDYEGTKEFSFKIVASDSGKPS----LNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGG-QPPRSSTAKVTINVMDVNDNSPVVISP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNN--KGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTA 778
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 235.728 bits (600), Expect = 3.329e-63 Identity = 220/785 (28.03%), Postives = 365/785 (46.50%), Query Frame = 2
Query: 296 YLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSS-VLTIAKNIDLESI--CINRELSSDCSSGQGHLELIVNLWSNVQLLA--VVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL-----AEHHKSFQLCLDQQ-RQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDL-YQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD---GLYEARSXXXXXXXXXXXXSPQL--------IQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEP-RLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS---LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSP-CLLTPFEFSVRENL-APATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFI 2563
Y + E +P + ++G++A D G+ H +YKL +D K+ + T +ID E + C N+ + C LE V++ VQ + ++ +I V D+NDN P F+ I + E ++ GS + ATD D P N Y L A+ Q+ DQ+ +QP L ++ +LD E Y + I+ + + + + + + V D NDN P+F + + EN+P + Q+ AND D + D + A +R+L + +N +I + +D E + V D AR+ + V V+D ND +P + + + E+ + + V V+D+D+ + N + C P +L + +G + K Y ++T T D EK ++ ++ D S N L+S+ ++ VQ++D NDN P F QS EN G V+ +V A D D G N ++ YSLE + + LF I G I V+ +DRE ++ Y+L + A D GS L + + + V D NDN P +L+ + FSV EN+ A + +G + D D G NA V S N D V+ GT+ + DRE + + +++ D G+ R G V I V+D NDN P + T+P+ + ++ G ++Q+ A D D N +LTY I N P +F S +G ++L+K + + G + + V V D G PP + +L++
Sbjct: 40 YKVPEEQPPNTLIGSLAAD---YGLPDVGH---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQIPGNPCI-----LEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTN-IGSLFPIPLATDRDAGP-NGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGE-NAAVTCVVAGDVPFQLRQASETGSDSK-KKYFLQTTTPLDYEKVKDYTIEIVAVD----SGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVG-VTINVLDENDNAPFI------------TAPSNTSHRLLTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGN--PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 790
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 235.728 bits (600), Expect = 3.329e-63 Identity = 220/785 (28.03%), Postives = 365/785 (46.50%), Query Frame = 2
Query: 296 YLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSS-VLTIAKNIDLESI--CINRELSSDCSSGQGHLELIVNLWSNVQLLA--VVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL-----AEHHKSFQLCLDQQ-RQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDL-YQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD---GLYEARSXXXXXXXXXXXXSPQL--------IQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEP-RLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS---LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSP-CLLTPFEFSVRENL-APATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFI 2563
Y + E +P + ++G++A D G+ H +YKL +D K+ + T +ID E + C N+ + C LE V++ VQ + ++ +I V D+NDN P F+ I + E ++ GS + ATD D P N Y L A+ Q+ DQ+ +QP L ++ +LD E Y + I+ + + + + + + V D NDN P+F + + EN+P + Q+ AND D + D + A +R+L + +N +I + +D E + V D AR+ + V V+D ND +P + + + E+ + + V V+D+D+ + N + C P +L + +G + K Y ++T T D EK ++ ++ D S N L+S+ ++ VQ++D NDN P F QS EN G V+ +V A D D G N ++ YSLE + + LF I G I V+ +DRE ++ Y+L + A D GS L + + + V D NDN P +L+ + FSV EN+ A + +G + D D G NA V S N D V+ GT+ + DRE + + +++ D G+ R G V I V+D NDN P + T+P+ + ++ G ++Q+ A D D N +LTY I N P +F S +G ++L+K + + G + + V V D G PP + +L++
Sbjct: 40 YKVPEEQPPNTLIGSLAAD---YGLPDVGH---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQIPGNPCI-----LEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTN-IGSLFPIPLATDRDAGP-NGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGE-NAAVTCVVAGDVPFQLRQASETGSDSK-KKYFLQTTTPLDYEKVKDYTIEIVAVD----SGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVG-VTINVLDENDNAPFI------------TAPSNTSHRLLTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGN--PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 790
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Match: Pcdh9 (protocadherin 9 [Source:MGI Symbol;Acc:MGI:1306801]) HSP 1 Score: 236.498 bits (602), Expect = 4.108e-63 Identity = 224/808 (27.72%), Postives = 364/808 (45.05%), Query Frame = 2
Query: 224 LKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEF--HGSLIYKLSGPNCCFSIDQKSS----VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPA 2578
L+ +L + C ++ I + ++ Y I+E P + +G I D+ IN SL+Y+L + + SS + T + ID E +C +S + EL V + N +++++I V D NDN P F I + E + S + +ATD D Q Y L F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F V + EN P + + QL A D D S + +R+ ++LF++ +I + LD E +KV V +DG AR+ + + V D ND P + I +P + + E I + V+DKD + NGK+IC E P F L + + + L + T + D E + + S ++ SD S L + + V++ D NDNPP F Q V+EN G + ++A D D G N I Y L + S F +D TGV+T +RE +E + + A D+G+ PL S + +TV D NDNSP F+F V ENL +T+G + D D G N V S N++ V+ +G + DRE + + V+ D G R S+ +V I V+DVNDN P +I+P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + +G + + V++ D G P + + N A
Sbjct: 3 LRDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAG---ASYAEENECFFELEVVILPN-DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFPIPSATDPDTGFNGVQ-HYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKD-TDVNGKVICFIEREVP---FHLKAVYDNQYL---LETSSLLDYEGTKEFSFKIVASDSGKPS----LNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFNREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDEDAGENKAVTLSILNDNENFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGG-QPPRSSTAKVTINVMDVNDNSPVVISP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDIDTGMNAELKYTIVSGNN--KGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKALHTLVLVFLYVNDTA 778
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Match: sp|Q9BZA7|PC11X_HUMAN (Protocadherin-11 X-linked OS=Homo sapiens OX=9606 GN=PCDH11X PE=2 SV=1) HSP 1 Score: 241.121 bits (614), Expect = 1.467e-63 Identity = 233/813 (28.66%), Postives = 372/813 (45.76%), Query Frame = 2
Query: 215 MDILKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDI-------EGLGINLEFHGSLIYKLSGPNCCFSIDQKSS-VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-LYEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMIC--EHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITN 2569
MD+L ++F + C +G +E Y I+E P + ++G + D+ + L ++F L+YK +G I++ + + T ID E +C C E+ V + + ++ +V++R + D+NDN P F I + E S S L A D D+ Q Y L + F L + + + P L + +LD E + Y++K++ + ++ + + + V D NDN P F + V + EN P + + QL A D D + + F +N R+LF + +I I LD E +K+ V +DG L AR+++ V V D ND P + I NP + + EN I + VTDKD + NG++ C +HE + F L + + L + T D E + + ++ L+ +D N S + +++ D NDN P F QS + EN G + KV+A D D G N KI+Y L D F +D TG++TV +DRE ++ Y I A D+G PL S+V + +++ D NDNSP + F V ENL T+G + D D G N+ V S NDD + + G + DRE ++ + V+ D G R SS +V I V+DVNDNKP I P P+ + +PG V+ Q+IAVD+D N ++ Y I+ NT +F+ + TG ++L + +G + + V D G P + +F + I N
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQE--KNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQF--KLVYK-TGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHC-----FYEVEVAILPD-EIFRLVKIRFLIEDINDNAPLFPATVINISIPENS-AINSKYTLPAAVDPDVGINGVQ-NYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKD-ADHNGRVTCFTDHE-----IPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLN----QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG-RVSRSSSAKVTINVVDVNDNKPVFIVP-----------PSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT--RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP----DSLFSVVIVN 769 HSP 2 Score: 125.946 bits (315), Expect = 9.535e-28 Identity = 106/354 (29.94%), Postives = 171/354 (48.31%), Query Frame = 2
Query: 1556 TSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-----LTPFEFSV--RENLAPAT-IGQLQYEDSDIGRNADVV-FS-KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
+S+ + V + D NDN P F++++ + EN P+GT + +++A D D G N KIH+S + S LF +++TTG+IT++ P+DRE ++KL + A D G +P + V +N+T DVNDN P + + P +V EN+ T I + D D N V F+ P + + L LD E+ + +++ D G QS+ + I+V D NDN P + ++SI SPG +T++ A+D D N K+ Y +L P+ P FS + TG L++ K L Y + KD+G PPL ++ I ++
Sbjct: 230 SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSA-MLFIKVKDENDNAPVFTQ--------------SFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINY-LLGPDAPPE--FSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQ 563 HSP 3 Score: 99.7525 bits (247), Expect = 9.449e-20 Identity = 106/354 (29.94%), Postives = 155/354 (43.79%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADV--VFSKTWPNDDTVMITVNGT---LYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPR-----LINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDAT-NTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F + + EN I + A D D G+NG +Y L ++ F L I++ G + VQ +DRE K+ Y + + D G +S+ L ++V D NDN P T E S+ EN T + QL D+DIG NA + FS N + +N T + I +PLDRE H L V D GL R V + V DVNDN P ++NP ++D S++I ++ LI V D DA N ++T + +P ++ S L L + Y IK+ D+G PPL M ++ + ++
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPAR---AMVLVNVTDVNDNVPSIDIRYIVNP-----VNDTV--VLSENIPLNTK-------IALITVTDKDADHNGRVT--CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE 459
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Match: sp|Q9HC56|PCDH9_HUMAN (Protocadherin-9 OS=Homo sapiens OX=9606 GN=PCDH9 PE=1 SV=2) HSP 1 Score: 239.965 bits (611), Expect = 2.525e-63 Identity = 224/791 (28.32%), Postives = 361/791 (45.64%), Query Frame = 2
Query: 224 LKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEF--HGSLIYKLSGPNCCFSIDQKSS----VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
L+ +L + C ++ I + ++ Y I+E P + +G I D+ IN SL+Y+L + + SS + T + ID E +C +S + EL V + N +++++I V D NDN P F I + E + S + +ATD D Q Y L F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F V + EN P + + QL A D D S + +R+ ++LF++ +I + LD E +KV V +DG AR+ + + V D ND P + I +P + + E I + V+DKD + NGK+IC E P F L + + + L + T + D E + + S ++ SD S L + + V++ D NDNPP F Q V+EN G + ++A D D G N I Y L + S F +D TGV+T DRE +E + + A D+G+ PL S + +TV D NDNSP F+F V ENL +T+G + D+D G N V S ND+ V+ +G + DRE + + V+ D G R S+ +V I V+DVNDN P +I+P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + +G + + V++ D G P
Sbjct: 3 LRDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAG---ASYAEENECFFELEVVILPN-DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFPIPSATDPDTGFNGVQ-HYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKD-TDVNGKVICFIEREVP---FHLKAVYDNQYL---LETSSLLDYEGTKEFSFKIVASDSGKPS----LNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGG-QPPRSSTAKVTINVMDVNDNSPVVISP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNN--KGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Match: sp|Q6X862|PC11X_GORGO (Protocadherin-11 X-linked OS=Gorilla gorilla gorilla OX=9595 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 239.195 bits (609), Expect = 7.038e-63 Identity = 232/813 (28.54%), Postives = 372/813 (45.76%), Query Frame = 2
Query: 215 MDILKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDI-------EGLGINLEFHGSLIYKLSGPNCCFSIDQKSS-VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-LYEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMIC--EHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITN 2569
MD+L ++F + C +G +E Y I+E P + ++G + D+ + L ++F L+YK +G I++ + + T ID E +C C E+ V + + ++ +V++R + D+NDN P F I + E S S L A D D+ Q Y L + F L + + + P L + +LD E + Y++K++ + ++ + + + V D NDN P F + V + EN P + + QL A D D + + F +N R+LF + +I I LD E +K+ V +DG L AR+++ V V D ND P + I NP + + EN I + VTDKD + NG++ C +HE + F L + + L + T D E + + ++ L+ +D N S + +++ D NDN P F QS + EN G + KV+A D D G N +I+Y L D F +D TG++TV +DRE ++ Y I A D+G PL S+V + +++ D NDNSP + F V ENL T+G + D D G N+ V S NDD + + G + DRE ++ + V+ D G R SS +V I V+DVNDNKP I P P+ + +PG V+ Q+IAVD+D N ++ Y I+ NT +F+ + TG ++L + +G + + V D G P + +F + I N
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQE--KNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQF--KLVYK-TGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHC-----FYEVEVAILPD-EIFRLVKIRFLIEDINDNAPLFPATVINISIPENS-AINSKYTLPAAVDPDVGINGVQ-NYELIKSQNMFGLDVIETPEGDKMPQLIVQKELDREKKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKD-ADHNGRVTCFTDHE-----IPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLN----QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG-RVSRSSSAKVTINVVDVNDNKPVFIVP-----------PSNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT--RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP----DSLFSVVIVN 769 HSP 2 Score: 125.946 bits (315), Expect = 1.150e-27 Identity = 165/588 (28.06%), Postives = 256/588 (43.54%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN----------DLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLF------SVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPAT-----IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDN--KPRLINPRGLREIDDATSP 2275
+++SV D NDN P F + IE + E + G+ + ATD DI ENA+I + + L + R+ LF LN LD E ++ + + A + V + V D NDN P + +V++ EN P + I + D D+ R + R L V N ++ +++LDYE + Y + + D ++L + V+DEND +P Q+ + + EN+ G+ + +V TD D S N ++ P EFSL + +LT + DREK + ++ D LTS+ T+ V I+D NDN P F ++Y +V EN P + + D D G N + S+ + F IDS TGVI DRE +E Y ++ A D G + +SS + I V DVNDN P + P E + P+T + Q+ D+D G NA+V +S N + T IT + D RV ++ N L G+ S V I + VN++ LIN + I+ +P
Sbjct: 235 LQVSVTDTNDNHPVFKETEIEVSIPENA-PVGTSVTQLHATDADIG-ENAKIHFSFS------NLVSNIARR--LFHLNATTGLITIKEPLDREETPNHKLLVLASDG--GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFR-LRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDAD-SGPNAEINYLLGPDAPP-EFSLD--RRTGMLTVVKK----LDREKEDKYLFTILAKDNGVPP----LTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDL-GQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTP 796 HSP 3 Score: 125.561 bits (314), Expect = 1.352e-27 Identity = 111/381 (29.13%), Postives = 178/381 (46.72%), Query Frame = 2
Query: 1475 FDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-----LTPFEFSV--RENLAPAT-IGQLQYEDSDIGRNADVV-FS-KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
DREK + + DG +S+ + V + D NDN P F++++ + EN P+GT + +++A D D G N KIH+S + S LF +++TTG+IT++ P+DRE ++KL + A D G +P + V +N+T DVNDN P + + P +V EN+ T I + D D N V F+ P + + L LD E+ + +++ D G QS+ + I+V D NDN P + ++SI SPG +T++ A D D N ++ Y +L P+ P FS + TG L++ K L Y + KD+G PPL ++ I ++
Sbjct: 207 LDREKKDTYVMKVKVEDGGFP----QRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSA-MLFIKVKDENDNAPVFTQ--------------SFVTVSIPENNSPGIQLTKVSATDADSGPNAEINY-LLGPDAPPE--FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQ 563 HSP 4 Score: 100.138 bits (248), Expect = 7.451e-20 Identity = 106/354 (29.94%), Postives = 155/354 (43.79%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADV--VFSKTWPNDDTVMITVNGT---LYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPR-----LINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDAT-NTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F + + EN I + A D D G+NG +Y L ++ F L I++ G + VQ +DRE K+ Y + + D G +S+ L ++V D NDN P T E S+ EN T + QL D+DIG NA + FS N + +N T + I +PLDRE H L V D GL R V + V DVNDN P ++NP ++D S++I ++ LI V D DA N ++T + +P ++ S L L + Y IK+ D+G PPL M ++ + ++
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNMFGLDVIETPEGDKMPQLIVQKELDREKKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPAR---AMVLVNVTDVNDNVPSIDIRYIVNP-----VNDTV--VLSENIPLNTK-------IALITVTDKDADHNGRVT--CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE 459
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Match: sp|Q6WXV7|PC11X_PONPY (Protocadherin-11 X-linked OS=Pongo pygmaeus OX=9600 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 238.424 bits (607), Expect = 9.920e-63 Identity = 230/812 (28.33%), Postives = 367/812 (45.20%), Query Frame = 2
Query: 215 MDILKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDI-------EGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-LYEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMIC--EHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITN 2569
MD+L ++F + C +G +E Y I+E P + ++G + D+ + L ++F L+YK + + T ID E +C C E+ V + + ++ +V++R + D+NDN P F I + E S S L A D D+ Q Y L + F L + + + P L + +LD E + Y++K++ + ++ + + + V D NDN P F + V + EN P + + QL A D D + + F +N R+LF + +I I LD E +K+ V +DG L AR+++ V V D ND P + I NP + + EN I + VTDKD + NG++ C +HE + F L + + L + T D E + + ++ L+ +D N S + +++ D NDN P F QS + EN G + KV+A D D G N +I+Y L D F +D TG++TV +DRE ++ Y I A D+G PL S+V + +++ D NDNSP + F V ENL T+G + D D G N+ V S NDD + + G + DRE ++ + V+ D G R SS +V I V+DVNDNKP I P P+ + +PG V+ Q+IAVD+D N ++ Y I+ NT +F+ + TG ++L + +G + + V D G P + +F + I N
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQE--KNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQF--KLVYKTGDVPLTRIEEDTGEIFTTGARIDREKLCAGIPRDEHC-----FYEVEVAILPD-EIFRLVKIRFLIEDINDNAPLFPATVINISIPENS-AINSKYTLPAAVDPDVGINGVQ-NYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPINDTVVLSENIPLNTKIALITVTDKD-ADHNGRVTCFTDHE-----IPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLN----QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG-RVSRSSSAKVTINVVDVNDNKPVFIVP-----------PSNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNT--RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP----DSLFSVVIVN 769 HSP 2 Score: 125.946 bits (315), Expect = 1.029e-27 Identity = 165/588 (28.06%), Postives = 256/588 (43.54%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN----------DLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLF------SVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPAT-----IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDN--KPRLINPRGLREIDDATSP 2275
+++SV D NDN P F + IE + E + G+ + ATD DI ENA+I + + L + R+ LF LN LD E ++ + + A + V + V D NDN P + +V++ EN P + I + D D+ R + R L V N ++ +++LDYE + Y + + D ++L + V+DEND +P Q+ + + EN+ G+ + +V TD D S N ++ P EFSL + +LT + DREK + ++ D LTS+ T+ V I+D NDN P F ++Y +V EN P + + D D G N + S+ + F IDS TGVI DRE +E Y ++ A D G + +SS + I V DVNDN P + P E + P+T + Q+ D+D G NA+V +S N + T IT + D RV ++ N L G+ S V I + VN++ LIN + I+ +P
Sbjct: 235 LQVSVTDTNDNHPVFKETEIEVSIPENA-PVGTSVTQLHATDADIG-ENAKIHFSFS------NLVSNIARR--LFHLNATTGLITIKEPLDREETPNHKLLVLASDG--GLMPARAMVLVNVTDVNDNVPSIDIRYIVNPINDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFR-LRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDAD-SGPNAEINYLLGPDAPP-EFSLD--RRTGMLTVVKK----LDREKEDKYLFTILAKDNGVPP----LTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDL-GQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTP 796 HSP 3 Score: 124.02 bits (310), Expect = 3.565e-27 Identity = 110/381 (28.87%), Postives = 178/381 (46.72%), Query Frame = 2
Query: 1475 FDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-----LTPFEFSV--RENLAPAT-IGQLQYEDSDIGRNADVV-FS-KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
DRE+ + + DG +S+ + V + D NDN P F++++ + EN P+GT + +++A D D G N KIH+S + S LF +++TTG+IT++ P+DRE ++KL + A D G +P + V +N+T DVNDN P + + P +V EN+ T I + D D N V F+ P + + L LD E+ + +++ D G QS+ + I+V D NDN P + ++SI SPG +T++ A D D N ++ Y +L P+ P FS + TG L++ K L Y + KD+G PPL ++ I ++
Sbjct: 207 LDREEKDTYVMKVKVEDGGFP----QRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVNPINDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSA-MLFIKVKDENDNAPVFTQ--------------SFVTVSIPENNSPGIQLTKVSATDADSGPNAEINY-LLGPDAPPE--FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQ 563 HSP 4 Score: 100.523 bits (249), Expect = 6.729e-20 Identity = 107/354 (30.23%), Postives = 155/354 (43.79%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADV--VFSKTWPNDDTVMITVNGT---LYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPR-----LINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDAT-NTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F + + EN I + A D D G+NG +Y L ++ F L I++ G + VQ +DRE K+ Y + + D G +S+ L ++V D NDN P T E S+ EN T + QL D+DIG NA + FS N + +N T + I +PLDRE H L V D GL R V + V DVNDN P ++NP I+D S++I ++ LI V D DA N ++T + +P ++ S L L + Y IK+ D+G PPL M ++ + ++
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPAR---AMVLVNVTDVNDNVPSIDIRYIVNP-----INDTV--VLSENIPLNTK-------IALITVTDKDADHNGRVT--CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE 459
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Match: sp|Q6WYY1|PC11X_PANPA (Protocadherin-11 X-linked OS=Pan paniscus OX=9597 GN=PCDH11X PE=3 SV=1) HSP 1 Score: 238.424 bits (607), Expect = 1.074e-62 Identity = 231/813 (28.41%), Postives = 372/813 (45.76%), Query Frame = 2
Query: 215 MDILKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDI-------EGLGINLEFHGSLIYKLSGPNCCFSIDQKSS-VLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMIC--EHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITN 2569
MD+L ++F + C +G +E Y I+E P + ++G + D+ + L ++F L+YK +G I++ + + T ID E +C C E+ V + + ++ +V++R + D+NDN P F I + E S S L A D D+ Q Y L + F L + + + P L + +LD E + Y++K++ + ++ + + + V D NDN P F + V + EN P + + QL A D D + + F +N R+LF + +I I LD E +K+ V +D GL AR+++ V V D ND P + I NP + + EN I + VTDK D+ NG++ C +HE + F L + + L + T D E + + ++ L+ +D N S + +++ D NDN P F QS + EN G + KV+A D D G N +I+Y L D F +D TG++TV +DRE ++ Y I A D+G PL S+V + +++ D NDNSP + F V ENL T+G + D D G N+ V S NDD + + G + DRE ++ + V+ D G R SS +V I V+DVNDNKP I P P+ + +PG V+ Q++AVD+D N ++ Y I+ NT +F+ + TG ++L + +G + + V D G P + +F + I N
Sbjct: 1 MDLLSGTYIFAVLLACVVFHSGAQE--KNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQF--KLVYK-TGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHC-----FYEVEVAILPD-EIFRLVKIRFLIEDINDNAPLFPATVINISIPENS-AINSKYTLPAAVDPDVGTNGVQ-NYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK-DADHNGRVTCFTDHE-----IPFRLRPVFSNQFL---LETAAYLDYESTKEYAIKLLAADAGKPPLN----QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG-RVSRSSSAKVTINVVDVNDNKPVFIVP-----------PSNYSYELVLPSTNPGTVVFQVMAVDNDTGMNAEVRYSIVGGNT--RDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP----DSLFSVVIVN 769 HSP 2 Score: 124.02 bits (310), Expect = 3.982e-27 Identity = 110/381 (28.87%), Postives = 178/381 (46.72%), Query Frame = 2
Query: 1475 FDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPC-----LLTPFEFSV--RENLAPAT-IGQLQYEDSDIGRNADVV-FS-KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
DRE+ + + DG +S+ + V + D NDN P F++++ + EN P+GT + +++A D D G N KIH+S + S LF +++TTG+IT++ P+DRE ++KL + A D G +P + V +N+T DVNDN P ++ P +V EN+ T I + D D N V F+ P + + L LD E+ + +++ D G QS+ + I+V D NDN P + ++SI SPG +T++ A D D N ++ Y +L P+ P FS + TG L++ K L Y + KD+G PPL ++ I ++
Sbjct: 207 LDREEKDTYVMKVKVEDGGFP----QRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSA-MLFIKVKDENDNAPVFTQ--------------SFVTVSIPENNSPGIQLTKVSATDADSGPNAEINY-LLGPDAPPE--FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQ 563
BLAST of Protocadherin alpha-2 vs. TrEMBL
Match: A0A4S2K5U7 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_011201 PE=4 SV=1) HSP 1 Score: 343.199 bits (879), Expect = 1.034e-94 Identity = 300/978 (30.67%), Postives = 458/978 (46.83%), Query Frame = 2
Query: 275 IKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGS-LIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQ-------GHL------------------------ELIVN-LWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKS----------FQLCLDQQRQPYLFLLNDLDAE-NQTHYLIKIR-----AWNAQDNKQW-----------------NELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPR---LEFSLSSGKNKKILTYDIRTKTAFDRE-----KSSQISVVLICSDGWN----TSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFE---------------------FSVRENLAPAT-IGQLQYEDSDIGRNADVVF--SKTWPNDDTVMITV--NGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREI--------DDA---------------------TSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNST---------TGYLSLDKPLSHHYIGHYPIKVSVKDSGSP-PLIDEKMFYLFITNKPA-------------------KYDDKLQSNNGGSWVDKNXXXXXXXXXXXXXXXXAMLVTAIICMLKPC 2722
I+E L++ I EN P+ +GT+ + I + G L Y+ P+ F++D+ S LT A ID ES+C +S Q GH+ L VN + S+ L AV R+ + V D+NDN P+FS+ R R + E ++ G + L A+D D+ E ++I+Y L S F+L + QP L L DLDAE N H + + WN + +W + L +++ V D NDN PRF+S + V + E+TP +MI++L+A+DPDST+ L + + +A + +++ V+ + S+L++E YKVP+ V DG + A+S L V V D NDE P+ NP + EN+ G +IG+V + D D NGK+ C R L F N YD+ T+ DRE + ++ V LICSDG + T++ T + + D ND+PP F QS Y V EN +G I++V A D D+G N KI YSL D + F++DS TG IT DRE ++ Y++ + A D G L+SSV LN+T+ DVND+ P LL P E F+++ENL+ T IG+L +D DIG NA + F +K P + NG+LY + LDRE K+ + L VR+ D S+G + I V+DVNDN P + P GL + DD+ TS ++ +SV + PGY+IT+L A D D N + Y + + + S + T +G + L + L+ +G + KV+ D G P PL D K+ + + + PA +++ +L G K++L ++ +L+ +S ++LVTAI+C+ PC
Sbjct: 45 IQERTLEFSIDENCPVGTELGTVV-----IPIAPHYMGPPLKYRFGSPSRLFAVDETSGQLTTAAPIDAESLCSKARQQEAGASSQSSDKQADGHMMRRHVPESEFTDQVTCSQSGAVSVHLDVNAIMSDSSLRAVHRISVRVQDLNDNGPKFSQVRWHRRLKEVLYRKGRRLDLPKASDADLLDEYSRIQYRLEPISNSTTKSSKLEIPFRLEVTPSGQPGLVLTEDLDAETNARHEFVLVAYSSAPVWNPSTSGKWSGLERGKMASQVPIPTEDRLYIEIEVADMNDNEPRFDSPSYKVSIAEDTPPGTMIYKLVAHDPDSTAQLVYSMGSSAEVAVMSATFNVESSGVVRLRSFLNFELRHTYKVPIRVNDGEFTAQSSLFVHVLDVNDEPPEFEVNPKRLVADENASVGKLIGRVRIQDPDSEAVNGKVECWEPEDLRRHQVLSFLPDPMSNPSASVYDLTTRVVLDREAFIGPQLGRLFVYLICSDGNGLPNENRPGVKHTATMTATLMVRDVNDHPPVFSQSVYHVAVRENNLLGEKIIQVKATDADEGDNAKISYSL-LDRANFKVDSLTGWITANVIFDRETRDSYQVTVVANDHGKERLSSSVLLNLTILDVNDHRPHLL-PCEGELPIIDRAHLQTGRIGDRNLFAIQENLSGNTFIGELLAKDDDIGLNAKLHFELAKETPLHYLTQFRLLHNGSLYTNRELDREEKEYYRLSVRVTDLSPTDPLSSTGTISIIVLDVNDNAPNFVQPSGLLRVGFDRPVVEDDSSPNILYDQPQLQNEVSSPVPLTSSNPKPTVLLSVREKPGYLITKLHAKDPDTGPNGHIRYTLAEFSDASTDFGSGSKTNPICRVTHDSGNVVLQRHLTVTDLGMHYFKVAAIDDGYPTPLKDTKILAVLVKDIPAVGSEPTNSLSSSYYSNNRTRFEFELWGFEG-----KSNLFIITVLASVSGLLASVLVTAIVCVSGPC 1010
BLAST of Protocadherin alpha-2 vs. TrEMBL
Match: A0A4S2KYT3 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_010451 PE=4 SV=1) HSP 1 Score: 336.265 bits (861), Expect = 1.231e-92 Identity = 279/939 (29.71%), Postives = 462/939 (49.20%), Query Frame = 2
Query: 290 LKYLIQENEPIDRMVGTIATDIEGLG----------INLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHV---SEASHKAGSHIFLETATDTDIAPENAQIEYGLAEH-----HK--SFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQ-------------WNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETT----EPRLEFS------------------LSSGKNKKILTYD---IRTKTAFDREK-SSQISVVLICSDGWN-------TSANIH-LTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF---SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLN---------------SSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFS-----KTWPNDD-----------TVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGL-REIDDATSPAASQ-----SISISVYQSPGYVITQLIAVDDDDATNTKLTYHI------LLPNTL---PSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYD-----------DKLQSNNGGSWVDKNXXXXXXXXXXXXXXXXAMLVTAIICMLKPC 2722
++Y I+EN+P + +G + D+ I +L Y+L P+ F + + +S L+ +IDLE++C R S+ Q L L V +W + +V+ V +++LDV+DN PQF +V E +KAG + L A D DI PENA+I+Y L H H +F L + L L DLD E Y + A + ++ ++L + + V + ND P F+ SL++V + E+T + + L A D D+ S + + L + +N+ LF V +G VIL ++ LD+E+ +Y +DG + A + L++ V D NDE P+ + NP +++V EN +GQ+++ D+D + NG++ C T +P L F + S N + Y + T+ FDRE S++ ++IC+DG + T+A I TS+ TI + + D NDN P F ++ Y A + EN P+GT +++V+A D D + K Y L + S F ++S TG I +DRE + Y+L + A+D G +P ++ + I + D NDN+P P +F+V EN AP+ IG LQ D D G N DV FS T +++ + +T NG+LY T+ LDRE + +C V ++D + S+ +C+RV+D+NDN P+ +N RG+ +++++ T A + ++S++ ++PGY A D D+ N L Y I + P ++ P F ++ +G L L + LS + IG YP+ + V+D G P L EK Y+ I + P + + + + +G + + +++LVVI LS +S A+L++AI+CM+KPC
Sbjct: 30 IRYAIKENQPENLRIGKLDEDLLQTPENENSELFSLIQSTKRSTLKYRLREPSNYFRLHESTSELSTKLSIDLEALC-PRFCREGLSAAQ--LNLFVAVWYEERPFSVIHVEVTILDVDDNSPQFPSTLSRPYVLQLKEVIYKAGKQVELPKAIDKDIQPENAEIQYRLQSHLDDSSHALDTFHLVTRNDSRVMLVLQKDLDYERVQQYRFYLVASSPVSEERRPFGYVLGPQSAFHDQLEIQVDVLNINDIEPVFSQSLYTVEIPEDTKIGTTVHVLQATDRDANSTIEYSL-ENSND----LFQVQADGKVIL-TNKLDFEKRNKYTFTARASDGEFYALTRLDITVTDVNDEPPEFVTNPPILKVEENQPSQTSVGQLLIVDRDSPEVNGRVTCHEPPTLAGRQPLLFFPETSSALPMPPGISLDGAIIDSSANPEHHVYQRFGLYTRMEFDRESDSNKHRSLIICTDGQDVLTSHTSTTAAIQPRTSTLTIMLTVTDQNDNAPFFEKTHYEAELQENCPVGTKVIQVHANDADSETHAKPQYHLLRNALFTSPFDVESETGWIITSADIDRETQALYQLTVLAID-GHLPRTNHRNGQTNFRGQQHTATTHVQIKILDDNDNAPEFRGPRQFAVEENQAPSKWIGDLQVLDRDEGINRDVEFSMANLQSTAASEEQNKTFRVRSIAPIKLTNNGSLYTTEVLDREVQAHYCFEVAVKDKSPSKPLSSTDTICVRVLDINDNTPKFVNIRGMSQDLNNRTDAKALEDLRDITVSLTFREAPGYCALIAEAEDSDEGRNALLRYTIKFDGDAMKPESVSHTPLDAFMMDTQSGRLMLTRTLSGNEIGAYPLTLVVEDGGIPSLKSEKDIYIIIEDGPPRGNWLFPESERSIASSVSAKDGNN--EAHTILVVIGLSGVSAFLAAVLISAILCMIKPC 956
BLAST of Protocadherin alpha-2 vs. TrEMBL
Match: A0A3R7CGZ3 (Protocadherin Fat 4 OS=Clonorchis sinensis OX=79923 GN=Fat4 PE=4 SV=1) HSP 1 Score: 333.183 bits (853), Expect = 1.273e-91 Identity = 280/940 (29.79%), Postives = 459/940 (48.83%), Query Frame = 2
Query: 290 LKYLIQENEPIDRMVGTIATDIEGLG----------INLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIER----HVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEH-----HK--SFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQ-------------WNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETT----EPRLEFS------------------LSSGKNKKILTYD---IRTKTAFDREK-SSQISVVLICSDGWN-----TSANIHL---TSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF---SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIP---------------LNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFS--------------KTWPNDDTVMI--TVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGL-REIDDATSPAASQ-----SISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLP-NTL--------PSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYD-----------DKLQSNNGGSWVDKNXXXXXXXXXXXXXXXXAMLVTAIICMLKPC 2722
++Y I+EN+P + +G + D+ I +L Y+L P+ F + + +S L+ +IDLE++C R S+ Q L L V +W + +V+ V +++LDV+DN PQF I R + E +KAG + L A D DI PENA+I+Y L H H +F L + L L DLD E Y + A + ++ ++L + + V + ND P F+ S+++V + E+ + + L A D D+ S + + L + + LF V +G VILI+ LD+E+ +Y +DG + A + L++ V D NDE P+ + NP +++V EN +GQ+++ D+D + NG++ C T +P L F + S N + Y + T+ FDRE S++ ++IC+DG + TS N+ + TS+ TI + + D NDN P F ++ Y A + EN P+GT +++V+A D D + K Y L + S F ++S TG I +DRE + Y+L + A+D G +P ++ + I + D NDN+P P +F+V EN AP+ IG LQ D D G N DV FS KT+ + I T NG+LY T+ LDRE + +C V ++D + S+ +C+RV+D+NDN P+ +N RG+ +++++ T A + ++S++ ++PGY A D D+ N L Y I +T+ P F ++ +G L L + LS + +G YP+ + V+D GSP L EK Y+ I + P + + + + G + + +++LVVI LS +S A+L++AI+CM+KPC
Sbjct: 30 IRYAIKENQPENLRIGKLDEDLLQTPENENSELFSLIQSTKRSTLKYRLREPSNYFRLHESTSELSTKVSIDLEALC-PRFCRDGLSAAQ--LNLFVAVWYEERPFSVIHVEVTILDVDDNSPQFPPT-ISRPYVLQLKEVIYKAGKQVELPKAIDKDIQPENAEIQYRLQSHLDDSSHALDTFHLVTRNDSRVMLVLQKDLDYERVQQYRFYLVASSPVSEERRPFGYVLDPQSAFHDQLEIQVDVLNINDIEPVFSQSIYNVEIPEDAKIGTTVHVLQATDRDANSTIEYSLENSND-----LFKVQADGKVILINK-LDFEKRNKYTFTARASDGEFYALTRLDITVTDVNDEPPEFVTNPPILKVEENQPSQTSVGQLLIVDRDSPEVNGRVTCHEPPTLAGRQPLLFFPETSNALPMPPGISLDGAIIDSSANPEHHVYQRFGLYTRVEFDRESDSNKHRSLIICTDGQDILTSHTSTNVAIQPRTSTLTILLTVTDQNDNAPFFEKTHYEAELQENCPVGTKVVQVHANDADSETHAKPQYHLLRNALFTSPFDVESETGWIITSADIDRETQALYQLTVLAID-GHLPGTNHRNGRSNFRGQQHTATTHVQIKILDDNDNAPEFRGPRQFAVEENQAPSKWIGDLQVLDRDEGINRDVEFSMANLPSTAASEEQNKTFRVRSVIPIKLTNNGSLYTTEVLDREIQAHYCFEVVVKDKSPSKPLSSTDTICVRVLDLNDNTPKFVNIRGMSQDLNNRTDAKAFEDLRDITVSLTFREAPGYCALIAEAEDSDEGRNALLRYTIKFDGDTMKTESVAHTPLDAFMMDAQSGRLMLTRTLSGNELGAYPLTLVVEDGGSPSLKSEKNIYIIIEDGPPRGNWLFPENERSIASSMSAKEGNN--EAHTILVVIGLSGVSAFLAAVLISAILCMIKPC 956
BLAST of Protocadherin alpha-2 vs. TrEMBL
Match: G4V8S4 (Putative cadherin OS=Schistosoma mansoni OX=6183 GN=Smp_129830 PE=4 SV=1) HSP 1 Score: 333.569 bits (854), Expect = 2.556e-91 Identity = 301/993 (30.31%), Postives = 456/993 (45.92%), Query Frame = 2
Query: 389 SLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESIC----------INRELSSDC------------------------SSGQGHLELIVN-LWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHH-----------KSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAW-----------NAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNE-LRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPR---LEFSLSSGKNKKILTYDIRTKTAFDREK-----SSQISVVLICSDG---------WNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFE---------------------FSVRENLAPAT-IGQLQYEDSDIGRNADVVF----SKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGL------------------------------------------REIDDATSP---------AASQSISISVYQSPGYVITQLIAVDDDDATNTKL------TYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL-IDEKMFYLFITNKPAKYDDKLQ--------SNNGGSWVDK------NXXXXXXXXXXXXXXXXAMLVTAIICMLKPCYQRNNNRYDKNWIKKISSGRTESMKN-----AGTIDSNSGAL 2833
+L YKL P+ FS+D++ +L +ID E++C IN SD SSG + VN + + L AV + + + D+NDN P+F + R + + EA ++AG I L A D DI E+++I Y L H F+L + QP L L DLDAE +T + + A+ N Q + + L +D+ V D NDN PRF+ +++++ V ENT ++I++L+A+DPDSTS L + + + + + F + +G V L SS LDYE Y +PV VTDG + AR+ L V V D NDE P NP + ENS G +IG+V + D D NG + C R L F N YD+ T+ DRE + + LICSDG N+ + I LTS+ T + I D ND+ P F S Y + EN PIG ++++ A+D D+G N +I YSL D + F++DS TG IT DRE ++ Y++ A+D+G L+SSV LNITV DVND+SP L + +E F VREN+ T +G + D D G NA + F + + + NG+LY LDRE KD + L V + D L+ ++G + I V+D+NDN+P+ ++P GL +E +SP A + +SVY+ P VI++L A D D N + Y + + P+ + TG L L + ++ +G++ KV+ D G P + ID+K+ L + +KPA SN G +D+ ++L++ LS +S A+L++A+ C+ KPC + NR+ + +GR ++N G DSN+G L
Sbjct: 88 ALNYKLGSPSTLFSVDERKGLLVTKADIDAEALCSYVTTLSPDHINNNDESDLMLEPGTSKNNRSKPIPVVDHIKCNSSGDLTVHFDVNAVQIDGSLRAVHHIVVRIHDLNDNGPKFDQIRWHKRLKEALYRAGRRIDLPKARDIDILAEHSRINYRLESWHNDGSSSIIPFKSPFKLEISNSGQPGLILTEDLDAEMETRHRFVLVAYSPNVIDSKNKLNGQAISRESRLEIDIEVADMNDNEPRFSFTVYNISVAENTSVGTVIYELVAHDPDSTSKLTYTMASSLEYQVMSSTFHIEADGHVRLHSS-LDYELRHIYSIPVEVTDGEFSARTTLNVQVLDVNDEPPAFELNPKQLIADENSPPGKLIGRVRIRDPDSPSVNGLVECSEPPGLVRRQALNFLPDPTVNPNAEVYDLTTRIMLDREDPENPIPGHLIIYLICSDGALSSGGMVSHNSDSKIRLTSTMTATLSIRDVNDHKPIFENSIYHMSIQENNPIGEKVVQIRAHDSDEGENARITYSLL-DRANFKVDSLTGWITPNVMFDRETRDSYQVTAIALDNGKPRLSSSVLLNITVLDVNDHSPVLAS-YEADESLLKTNDLPVGRFGLKNLFIVRENMPVNTYMGNILASDKDEGLNAQLRFMLFPDPVYRIHERFRLLPNGSLYTNVELDREEKDHYRLTVVVSDQSLDEPLTTTGTIGIIVLDLNDNQPQFLSPHGLLIPNNTQLSGYKRHMNRGIELYDQPSEDHNYNVAKGNQKRSDQEYQSESSPLTDTNTQSTAPEPVVRLSVYEKPDQVISKLYAEDPDAGDNGAVFYLLEEFYDLSVDKIRPNPLIRVQPETGELILIRHMAPIDLGYHFFKVTASDRGHPRMKIDQKILPLLVEDKPASGGLGQSSLSSSYYVSNITGLGLDEWGPSGGRNILIITALSIVSGILAAILISAVFCVTKPCSR---NRHGNRCV----NGRHNRLRNRPPTYPGGPDSNNGIL 1070
BLAST of Protocadherin alpha-2 vs. TrEMBL
Match: A0A3Q0KLK9 (Putative cadherin OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 333.569 bits (854), Expect = 2.805e-91 Identity = 301/993 (30.31%), Postives = 456/993 (45.92%), Query Frame = 2
Query: 389 SLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESIC----------INRELSSDC------------------------SSGQGHLELIVN-LWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHH-----------KSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAW-----------NAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNE-LRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPR---LEFSLSSGKNKKILTYDIRTKTAFDREK-----SSQISVVLICSDG---------WNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFE---------------------FSVRENLAPAT-IGQLQYEDSDIGRNADVVF----SKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGL------------------------------------------REIDDATSP---------AASQSISISVYQSPGYVITQLIAVDDDDATNTKL------TYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL-IDEKMFYLFITNKPAKYDDKLQ--------SNNGGSWVDK------NXXXXXXXXXXXXXXXXAMLVTAIICMLKPCYQRNNNRYDKNWIKKISSGRTESMKN-----AGTIDSNSGAL 2833
+L YKL P+ FS+D++ +L +ID E++C IN SD SSG + VN + + L AV + + + D+NDN P+F + R + + EA ++AG I L A D DI E+++I Y L H F+L + QP L L DLDAE +T + + A+ N Q + + L +D+ V D NDN PRF+ +++++ V ENT ++I++L+A+DPDSTS L + + + + + F + +G V L SS LDYE Y +PV VTDG + AR+ L V V D NDE P NP + ENS G +IG+V + D D NG + C R L F N YD+ T+ DRE + + LICSDG N+ + I LTS+ T + I D ND+ P F S Y + EN PIG ++++ A+D D+G N +I YSL D + F++DS TG IT DRE ++ Y++ A+D+G L+SSV LNITV DVND+SP L + +E F VREN+ T +G + D D G NA + F + + + NG+LY LDRE KD + L V + D L+ ++G + I V+D+NDN+P+ ++P GL +E +SP A + +SVY+ P VI++L A D D N + Y + + P+ + TG L L + ++ +G++ KV+ D G P + ID+K+ L + +KPA SN G +D+ ++L++ LS +S A+L++A+ C+ KPC + NR+ + +GR ++N G DSN+G L
Sbjct: 88 ALNYKLGSPSTLFSVDERKGLLVTKADIDAEALCSYVTTLSPDHINNNDESDLMLEPGTSKNNRSKPIPVVDHIKCNSSGDLTVHFDVNAVQIDGSLRAVHHIVVRIHDLNDNGPKFDQIRWHKRLKEALYRAGRRIDLPKARDIDILAEHSRINYRLESWHNDGSSSIIPFKSPFKLEISNSGQPGLILTEDLDAEMETRHRFVLVAYSPNVIDSKNKLNGQAISRESRLEIDIEVADMNDNEPRFSFTVYNISVAENTSVGTVIYELVAHDPDSTSKLTYTMASSLEYQVMSSTFHIEADGHVRLHSS-LDYELRHIYSIPVEVTDGEFSARTTLNVQVLDVNDEPPAFELNPKQLIADENSPPGKLIGRVRIRDPDSPSVNGLVECSEPPGLVRRQALNFLPDPTVNPNAEVYDLTTRIMLDREDPENPIPGHLIIYLICSDGVLSSGGMVSHNSDSKIRLTSTMTATLSIRDVNDHKPIFENSIYHMSIQENNPIGEKVVQIRAHDSDEGENARITYSLL-DRANFKVDSLTGWITPNVMFDRETRDSYQVTAIALDNGKPRLSSSVLLNITVLDVNDHSPVLAS-YEADESLLKTNDLPVGRFGLKNLFIVRENMPVNTYMGNILASDKDEGLNAQLRFMLFPDPVYRIHERFRLLPNGSLYTNVELDREEKDHYRLTVVVSDQSLDEPLTTTGTIGIIVLDLNDNQPQFLSPHGLLIPNNTQLSGYKRHMNRGIELYDQPSEDHNYNVAKGNQKRSDQEYQSESSPLTDTNTQSTAPEPVVRLSVYEKPDQVISKLYAEDPDAGDNGAVFYLLEEFYDLSVDKIRPNPLIRVQPETGELILIRHMAPIDLGYHFFKVTASDRGHPRMKIDQKILPLLVEDKPASGGLGQSSLSSSYYVSNITGLGLDEWGPSGGRNILIITALSIVSGILAAILISAVFCVTKPCSR---NRHGNRCV----NGRHNRLRNRPPTYPGGPDSNNGIL 1070
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 235.343 bits (599), Expect = 4.195e-63 Identity = 217/778 (27.89%), Postives = 364/778 (46.79%), Query Frame = 2
Query: 296 YLIQENEPIDRMVGTIATDIE-GLGINLEFHGSL----IYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-LYEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDE-KMFYLFI 2563
Y ++E +P + +G + TD++ L N++ +L +YK + T A ID E +C S + + E+ V + + ++ +V++R + D+NDN P F I + E + + + +A D D+ Q Y L + F L + + + P L + +LD E + +++KI+ + + + + + + V D NDN P F S V V EN P + + QL A D D S + + F + ++ F++ + +I + LD E + +K+ V +DG +R+ + V V D ND P + I NP + + EN+ I + VTD+ D+ NGK+ C T+ + F L N + L + T D E + + ++ ++ SD S L +S + ++I D NDN P F Q + + EN GT ++K+ A D D G N I YSL D F ID +G+++V +DRE +E Y + A D+GS PL S+V + + V D NDNSP + F V ENL T+G + D+D G NA V S D+ ++ G + DRE + + V+ D+GL + S +V I V+DVNDN+P + P D + +PG V+T++ A+D+D N +L Y I+ P +F+ + TTG ++L + +++ G + + V VKD G P + + +LF+
Sbjct: 68 YTVKEEQPENVRIGNLRTDLDLNLDPNIKLSSALQFKPVYKTGDVPLVRVEASTGEIFTTANRIDRERLC-----SGVFNEKRCFYEIEVAVLPD-EIFRLVKIRFLIEDINDNAPLFQSTVINISIPENT-AINNRYPVPSAFDPDVGINGIQ-HYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDR-DADLNGKVTC---YTDHDVPFRLKPVFNDQFL---LETAAPLDYETTREYAIKIVASD----SGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDADAGDNAIVTLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGL-IQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYD-----------LVPFTTNPGSVVTRVFAIDNDTGMNAELQYSII--GGSPRGLFAIDKTTGNITLQEKIANADQGLHRLVVKVKDLGQPESLHSIALVHLFV 812 HSP 2 Score: 105.916 bits (263), Expect = 1.348e-22 Identity = 102/349 (29.23%), Postives = 155/349 (44.41%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQID---STTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFS---KTWPNDDT--VMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDA-TNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F+ + + EN I +A+D D G+NG HY L S F +D + G + VQ +DRE K+ + + I D G+ P +S+ L +TV DVNDN P + E +V EN T + QL D+D+G NA + FS + P + + G + + +PLDRE+ H L V D R + V + V DVNDN P + + ++ + + ++ + LI V D DA N K+T + + +P ++ + L PL + Y IK+ DSG PPL M + I ++
Sbjct: 165 IRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRAT---VIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKI---------ALITVTDRDADLNGKVTCYT--DHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDE 499
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 233.417 bits (594), Expect = 1.249e-62 Identity = 223/807 (27.63%), Postives = 374/807 (46.34%), Query Frame = 2
Query: 224 LKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGS--LIYKL---SGPNCCFSI-DQKSSVLTIAKNIDLESICINRELS-SDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYE-ARSXXXXXXXXXXXXSPQL----IQNPS--VIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDE-KMFYLFITN 2569
LK +L T V C + I + ++ Y I+E + ++G I D+ +N S L+Y+L +G N + + T + ID E +C S+CS E+ V + N +++++I V D NDN P F I + E + S + +ATD D+ P N+ +Y L +F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F S V + E++P + + QL A D D + + +++ + R+LF++ +I + LD E +K+ V +DG AR+ + + V D ND +P + I +P+ + + E I + V+DKD + NGK+IC E P F L + + + Y + T D E + + ++ SD S N + + V++ D NDNPP F Q V+EN + + A D D G N +I Y L + S F +D TGV+T DRE +E + + A D+G+ L S + +T+ D NDNSP F+F V ENL +T+G + D+D G NA V S N++ ++ G + DRE + + VR D+G + S+ +V I VIDVNDN P +I P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + G + + V++ D G P + + +L++ N
Sbjct: 3 LKDFYLLATLVACLWLDPAIAQELI-YPIREELQENVLIGNIPKDLNISHMNTATGASNNLVYRLVSKAGDNPLLRVMSNTGEIFTTSNRIDREKLCPGPSYEDSECS-----FEIEVVILPN-DYFRLIKIKIVVKDTNDNAPMFPSPVINISIPENT-LINSRFAIPSATDPDMGP-NSVYKYELVNGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPESSPVGTSVVQLQATDADVGANAEIKYMFGTQVSPATRRLFALNSTTGLITVQRPLDREETANHKLSVLASDGSSSSARATVTINVTDVNDNAPNIDLRYIISPTNGTVLLSEKDPVNTKIALITVSDKD-TDVNGKVICFIEKDVP---FHLKAVYDNQ---YLLETSALLDYEGTKEYIFKIVASDSGKPSLN----QTALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREDQERFLFTVTARDNGTRALQSQAAVIVTILDQNDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVSLSILNDNENFILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSG-HPPCSSAAKVTINVIDVNDNPPIVIYP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVNGNN--KGLFRIDPVTGNITLEEKPTEADSGLHRLVVNISDLGYPKSLHTLVLVFLYVNN 775
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 234.958 bits (598), Expect = 1.289e-62 Identity = 217/778 (27.89%), Postives = 364/778 (46.79%), Query Frame = 2
Query: 296 YLIQENEPIDRMVGTIATDIE-GLGINLEFHGSL----IYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-LYEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDE-KMFYLFI 2563
Y ++E +P + +G + TD++ L N++ +L +YK + T A ID E +C S + + E+ V + + ++ +V++R + D+NDN P F I + E + + + +A D D+ Q Y L + F L + + + P L + +LD E + +++KI+ + + + + + + V D NDN P F S V V EN P + + QL A D D S + + F + ++ F++ + +I + LD E + +K+ V +DG +R+ + V V D ND P + I NP + + EN+ I + VTD+ D+ NGK+ C T+ + F L N + L + T D E + + ++ ++ SD S L +S + ++I D NDN P F Q + + EN GT ++K+ A D D G N I YSL D F ID +G+++V +DRE +E Y + A D+GS PL S+V + + V D NDNSP + F V ENL T+G + D+D G NA V S D+ ++ G + DRE + + V+ D+GL + S +V I V+DVNDN+P + P D + +PG V+T++ A+D+D N +L Y I+ P +F+ + TTG ++L + +++ G + + V VKD G P + + +LF+
Sbjct: 68 YTVKEEQPENVRIGNLRTDLDLNLDPNIKLSSALQFKPVYKTGDVPLVRVEASTGEIFTTANRIDRERLC-----SGVFNEKRCFYEIEVAVLPD-EIFRLVKIRFLIEDINDNAPLFQSTVINISIPENT-AINNRYPVPSAFDPDVGINGIQ-HYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDR-DADLNGKVTC---YTDHDVPFRLKPVFNDQFL---LETAAPLDYETTREYAIKIVASD----SGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDADAGDNAIVTLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGLI-QTTSYAKVTINVVDVNDNRPVFVIPSSNYSYD-----------LVPFTTNPGSVVTRVFAIDNDTGMNAELQYSII--GGSPRGLFAIDKTTGNITLQEKIANADQGLHRLVVKVKDLGQPESLHSIALVHLFV 812 HSP 2 Score: 105.916 bits (263), Expect = 1.402e-22 Identity = 102/349 (29.23%), Postives = 155/349 (44.41%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQID---STTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFS---KTWPNDDT--VMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDA-TNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F+ + + EN I +A+D D G+NG HY L S F +D + G + VQ +DRE K+ + + I D G+ P +S+ L +TV DVNDN P + E +V EN T + QL D+D+G NA + FS + P + + G + + +PLDRE+ H L V D R + V + V DVNDN P + + ++ + + ++ + LI V D DA N K+T + + +P ++ + L PL + Y IK+ DSG PPL M + I ++
Sbjct: 165 IRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRAT---VIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKI---------ALITVTDRDADLNGKVTCYT--DHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDE 499
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 234.187 bits (596), Expect = 2.145e-62 Identity = 215/778 (27.63%), Postives = 362/778 (46.53%), Query Frame = 2
Query: 296 YLIQENEPIDRMVGTIATDIE-GLGINLEFHGSL----IYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQ----IEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-LYEARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDE-KMFYLFI 2563
Y ++E +P + +G + TD++ L N++ +L +YK + T A ID E +C S + + E+ V + + ++ +V++R + D+NDN P F I + E + + + +A D D+ Q ++ G E + + P L + +LD E + +++KI+ + + + + + + V D NDN P F S V V EN P + + QL A D D S + + F + ++ F++ + +I + LD E + +K+ V +DG +R+ + V V D ND P + I NP + + EN+ I + VTD+ D+ NGK+ C T+ + F L N + L + T D E + + ++ ++ SD S L +S + ++I D NDN P F Q + + EN GT ++K+ A D D G N I YSL D F ID +G+++V +DRE +E Y + A D+GS PL S+V + + V D NDNSP + F V ENL T+G + D+D G NA V S D+ ++ G + DRE + + V+ D+GL + S +V I V+DVNDN+P + P D + +PG V+T++ A+D+D N +L Y I+ P +F+ + TTG ++L + +++ G + + V VKD G P + + +LF+
Sbjct: 28 YTVKEEQPENVRIGNLRTDLDLNLDPNIKLSSALQFKPVYKTGDVPLVRVEASTGEIFTTANRIDRERLC-----SGVFNEKRCFYEIEVAVLPD-EIFRLVKIRFLIEDINDNAPLFQSTVINISIPENT-AINNRYPVPSAFDPDVGINGIQHYELVKVGALEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDR-DADLNGKVTC---YTDHDVPFRLKPVFNDQFL---LETAAPLDYETTREYAIKIVASD----SGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPENLPLYGTVGLITVTDADAGDNAIVTLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSGLI-QTTSYAKVTINVVDVNDNRPVFVIPSSNYSYD-----------LVPFTTNPGSVVTRVFAIDNDTGMNAELQYSII--GGSPRGLFAIDKTTGNITLQEKIANADQGLHRLVVKVKDLGQPESLHSIALVHLFV 773 HSP 2 Score: 105.916 bits (263), Expect = 1.542e-22 Identity = 102/350 (29.14%), Postives = 156/350 (44.57%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEH----DFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFS---KTWPNDDT--VMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDA-TNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
I I D NDN P F+ + + EN I +A+D D G+NG HY L +F L I++ G + VQ +DRE K+ + + I D G+ P +S+ L +TV DVNDN P + E +V EN T + QL D+D+G NA + FS + P + + G + + +PLDRE+ H L V D R + V + V DVNDN P + + ++ + + ++ + LI V D DA N K+T + + +P ++ + L PL + Y IK+ DSG PPL M + I ++
Sbjct: 125 IRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKVGALEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRAT---VIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKI---------ALITVTDRDADLNGKVTCYT--DHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDE 460
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Match: pcdh9 (protocadherin 9 [Source:ZFIN;Acc:ZDB-GENE-091015-1]) HSP 1 Score: 233.032 bits (593), Expect = 2.222e-62 Identity = 223/807 (27.63%), Postives = 374/807 (46.34%), Query Frame = 2
Query: 224 LKTLFLFLTAVRCS--ETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGS--LIYKL---SGPNCCFSI-DQKSSVLTIAKNIDLESICINRELS-SDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYE-ARSXXXXXXXXXXXXSPQL----IQNPS--VIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDE-KMFYLFITN 2569
LK +L T V C + I + ++ Y I+E + ++G I D+ +N S L+Y+L +G N + + T + ID E +C S+CS E+ V + N +++++I V D NDN P F I + E + S + +ATD D+ P N+ +Y L +F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F S V + E++P + + QL A D D + + +++ + R+LF++ +I + LD E +K+ V +DG AR+ + + V D ND +P + I +P+ + + E I + V+DKD + NGK+IC E P F L + + + Y + T D E + + ++ SD S N + + V++ D NDNPP F Q V+EN + + A D D G N +I Y L + S F +D TGV+T DRE +E + + A D+G+ L S + +T+ D NDNSP F+F V ENL +T+G + D+D G NA V S N++ ++ G + DRE + + VR D+G + S+ +V I VIDVNDN P +I P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + G + + V++ D G P + + +L++ N
Sbjct: 3 LKDFYLLATLVACLWLDPAIAQELI-YPIREELQENVLIGNIPKDLNISHMNTATGASNNLVYRLVSKAGDNPLLRVMSNTGEIFTTSNRIDREKLCPGPSYEDSECS-----FEIEVVILPN-DYFRLIKIKIVVKDTNDNAPMFPSPVINISIPENT-LINSRFAIPSATDPDMGP-NSVYKYELVNGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNRPVFKESQIEVHIPESSPVGTSVVQLQATDADVGANAEIKYMFGTQVSPATRRLFALNSTTGLITVQRPLDREETANHKLSVLASDGSSSSARATVTINVTDVNDNAPNIDLRYIISPTNGTVLLSEKDPVNTKIALITVSDKD-TDVNGKVICFIEKDVP---FHLKAVYDNQ---YLLETSALLDYEGTKEYIFKIVASDSGKPSLN----QTALVRVRLEDENDNPPIFTQPVIELTVSENNKRDLYLTTITATDEDSGRNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREDQERFLFTVTARDNGTRALQSQAAVIVTILDQNDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENAVVSLSILNDNENFILDPYTGVIKSNVSFDREQQSSYTFDVRAVDSG-HPPCSSAAKVTINVIDVNDNPPIVIYP-----------PSNTSFKLVPLSAIPGSVVAEVFAVDGDTGMNAELKYTIVNGNN--KGLFRIDPVTGNITLEEKPTEADSGLHRLVVNISDLGYPKSLHTLVLVFLYVNN 775
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 216.853 bits (551), Expect = 4.158e-58 Identity = 219/792 (27.65%), Postives = 362/792 (45.71%), Query Frame = 2
Query: 278 KECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKL-------SGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQ---LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHH----KSFQLCLDQ----QRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTS----VLRF---DLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYE---ARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF-SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSG 2521
+E + Y + E +G + D+ NLE L YK+ + P + + + +D E++C ++ +C H+++ V + VQ ++ VRI+V D+NDN P F+ + V E + AG ++ A D D + N Y L +F+L + + ++ PYL + LD E + Y + +RA + + + V D NDN P F+ + +V + EN+P + + QL A+D D+ S V R + ++LF + QN ++ ++ L+ E Y++ + TD E A + + V V D ND SP + I P VI + E S L + + V+D D NG + C P + F L K LTY + T+ D E ++ V + +D TS L+ + ++ +++LD NDN P F + Y V EN IG ++ V+A D D N ++ Y L D ++F +D TG+I++ +DRE K +Y I A D G L + + + V DVNDN P L F+F V EN+ +T+G + DSD G N V S D+ + +++ G + DRE + + L V+ D G R S+ +V I V+D+NDN P ++ P P+ + + PG ++T++ AVD+D N +L YHI+ N P +F + G ++L +PL+ + G + + V V D G
Sbjct: 35 EEFKVSYRVAEELREGAFIGNPSVDLRLADYNLE----LTYKVMLSKAEDAAPPLVRVNPRTGELFAAGRKMDREALCGGQDPGDEC-----HVDVQVGVLP-VQPGPFFKLIEVRINVEDINDNAPAFAAPVLTVSVPENA-PAGKRFPIQPANDPD-SEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEASHVNLPVALITVSDPDIG-ANGAVTC--YIYNPEVPFQL------KKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATS----LSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPDAPTMFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENVPKHSTVGMVTVADSDEGENGRVRLS-ILGTDNRQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGG-EPVRSSTVKVVIHVMDINDNSPIVLMP-----------PSNTTYKFVVPRTLPGTIVTEVSAVDNDAEINAELRYHIVGGN--PHNLFHIDPVIGNITLMEPLTETHHGLHRLVVRVSDIG 786 HSP 2 Score: 106.686 bits (265), Expect = 1.363e-23 Identity = 142/604 (23.51%), Postives = 262/604 (43.38%), Query Frame = 2
Query: 833 DAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTS--VLRFDLYQTANNELRKL-FSVLQ--NGTVI---LISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGW--------NTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTG----VITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPATIGQ----LQYEDSDIGRNADVVFSKTWPNDDTV--MITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYL----SLDKPLSHHYIGHYPIKVSVKDSGSP 2527
D ++ H +++ Q + + V + V+D NDN P F + + +V V EN PA ANDPDS + V R++L + + SV + NG + ++ LD E Q Y++ + DG + +VL + V D ND SP Q +E+ ENS G + Q+ +D+D + +N +++ T+ + S K++ D + +RE+S ++++ +D + + + + ++I D +++E + + + D D G NG + + + FQ+ T ++ + +D E K Y + I A D+G+ L+ ++ + I + D NDN+P P ++ SV EN IG+ + D D+ +NA++V+ P+ T+ M G + +T+ LDRE K + + +D G+ + + V + V+DVNDN+PR L E D + + ++ + + D D+ N ++ IL T Q+FS + +G + D+ H+Y+ ++V D G P
Sbjct: 112 DPGDECHVDVQVGVLPVQPGPFFKLIEVRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRD-AGSNAEVVYRLGTST---GGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDI------VAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVPFQLKKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPEN---NVIGKHLITVSATDRDMDKNAEMVYF-LGPDAPTMFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIP-VLEGNATVIVNVLDVNDNRPRF----SLAEFDFYVNENVPKHSTVGM----------VTVADSDEGENGRVRLSIL--GTDNRQLFSIDPESGMIRSNVGFDREQRHYYV----LEVQATDGGEP 680 HSP 3 Score: 101.293 bits (251), Expect = 6.676e-22 Identity = 143/554 (25.81%), Postives = 232/554 (41.88%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLND----------LDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFN-----SSLFSVL-VKENTPARSMIFQLIANDPD---STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-----FEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTV--MITVNGTLYITKPLDRETKDRHCLRVRLRDNGL 2158
+RI+V D NDN P F + + + E S G+H+ A+D D A NA++ Y L +R LF L+ L+ E Y I I A + V + V D NDN P + + V+ + E + + + +DPD + +V + +L+KL N ++ LDYE Y V + D + S + D +P + + V EN+ G + V TD+D + N +M+ P + F + LT + DREK + S ++ D L + T+ V +LD NDN P+F +++ +V EN P + + V D D+G NG++ S+ + LF ID +G+I DRE + +Y L + A D G +S+V + I V D+NDNSP +L P ++F V L + ++ D+D NA++ + N + + V G + + +PL H L VR+ D G+
Sbjct: 253 LRINVTDTNDNSPVFDQAEVNVEIPENS-PVGTHVVQLHASDRD-AGSNAEVVYRLGTSTGGAGSGQGGKR---LFRLDQNSGLVTVNGLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVPFQLKKL--TYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDK-NAEMVYFLGPDAPTM-FHMDPETGIISLTEQL------DREKKANYSFTILAKD----QGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNENVPKHSTVGMVTVADSDEGENGRVRLSILGTDNRQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVRSSTVKVVIHVMDINDNSPIVLMPPSNTTYKFVVPRTLPGTIVTEVSAVDNDAEINAELRYHIVGGNPHNLFHIDPVIGNITLMEPLTETHHGLHRLVVRVSDIGI 787 HSP 4 Score: 97.8265 bits (242), Expect = 8.993e-21 Identity = 108/426 (25.35%), Postives = 187/426 (43.90%), Query Frame = 2
Query: 1352 DSQTNG----KMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS----------LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPAT--------------IGQLQYEDSDIGRNADV---VFSKTWPNDDTVMITVNGTLYITKP-LDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
DS+ NG +++ T E S++ N + + Y + + + DRE+ + L DG + + S + + + D NDN P F Q++ + EN P+GT +++++A D D G N ++ Y L LF++D +G++TV G ++RE Y++ I A D G P+ ++ + +TV DVNDNSP + +R+ +AP + + D DIG N V +++ P + N L T+ LD ETK+ + ++++ D G ++ V I+++D NDN P P + +S+ G + + A D D N ++ Y L P+ +F + TG +SL + L +Y + KD G P L
Sbjct: 181 DSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPY-LVVRKSLDREERQLYEMNLRAVDGGSPPH----SGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTI------EIRDIVAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVPFQLKKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTM-SVTIKLLDSNDNAPVFTEP--------------TYKVSVPENNVIGKHLITVSATDRDMDKNAEMVY-FLGPDA--PTMFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIPVL 577
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 183.726 bits (465), Expect = 4.724e-47 Identity = 179/629 (28.46%), Postives = 281/629 (44.67%), Query Frame = 2
Query: 587 RVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTP-----ARSMIFQLIANDPDSTSVLRFDLYQTANNE----LRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSV-IEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTY----DIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHD-----------FSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVF--SKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL-INPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTY 2383
+V ISV DVNDN P F+ +E V E + + G IF +ATD D +NA + Y + + +D L LD E + YL+ +R A D + + + V D NDN PRF+ +S V E+ R++I ++A D DS Y A +E F + + ++ LD E Y + TDG A + + + +++ +QN S+ EV E++ G + ++ TD D E LEFS+SSG + + A DRE+ S ++V+ SD L+S+ +++ + D NDN P F S A E+ P+G V+ V A D D G N + Y+L D F +++ TG + + +DRE ++ Y L + AVD G PL S+ L +TV D NDN+P +E ++ E+ P T + +L D D G N ++ + + P D + V GTL + +PLDRE + L VR RD G R + V + + DVND P ++P + ++ Q P +I Q++A DDD ++ ++TY
Sbjct: 1501 QVEISVEDVNDNPPVFAVPEMELEVEENTGE-GEVIFTLSATDADQG-QNALVTYSVLSGSEG-AFVVDAASG-VLRASRRLDREERASYLLTVR---ASDGTHATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEV-TYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGGLAATARLYVNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDD------------EGVNAELEFSISSGDPEGRFAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPP-ARLSSAVRVSLILTDVNDNAPAF-TSPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGG-GPARSDTASVRVTLSDVNDCSPAFQLSPYTVHARENT--------------QGPPVLILQVVARDDDLGSSGQVTY 2092 HSP 2 Score: 168.703 bits (426), Expect = 2.400e-42 Identity = 152/569 (26.71%), Postives = 251/569 (44.11%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENA-QIEYGLAEHHKSFQLCLDQQRQPYLFL----LNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSW--LDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSP--QLIQNPSVIE---VMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVV--FSKTWPNDDTVMI---TVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKP 2224
VR+ V DVNDN P F + + + G + L+TA D D+ P Y + ++ +L + FL LD E Y + ++A + +++ L V++ V D NDNPP F + V E++P + + L+ + R +V + ++S+ LD+E ++Y + + DG R+ + + D ND P + + P V E++ G V V VTD D NG++ R F L + + ++ + DRE+ ++ ++ SD A +++ ++ V + D ND+ P+F S Y A ++E P G+ + V A D D GLN K+ YS+ +D F +D +TG++T G VDRE+ L+I A D G+ P + L +T+ DVND P T + + EN P + + DSD+G N V F P M ++ G + K LDRE + + L V+ +D G + S+ +V + V D+NDN P
Sbjct: 9 VRVVVGDVNDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDSPVGAALRDLL-------------------HRGRGPLAVPFDPKTGMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRV--LKVASQLDRERIPMYNLTILASDNGKPVAR---SATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGWFSVDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRG-SPPLGSTAKVTVVVGDLNDNHP 552 HSP 3 Score: 164.851 bits (416), Expect = 3.397e-41 Identity = 196/775 (25.29%), Postives = 328/775 (42.32%), Query Frame = 2
Query: 332 VGTIATDIEGLGINLEFHGSLIYKLSGPN--CCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQ----LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLET--ATDTDIAPENAQIEYGL-----AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLY-EARSXX--XXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSL--SSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEH-----DFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP---FEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRH------CLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSP----GYVITQLIAV---DDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
G+ D+ + + + L Y + N FS+D+ + ++T +D RE++S +++N+ + Q A + +++LDVND P F++ + +V+ A + +F+ + A D+D+ EN + Y A++ + F+L + L LD E Y + ++A + + V + V D NDN P F + + EN P + + + A DPD + +R+ L TA + R + + +S LD E Y++ V DG + ARS + V D D P ++ V EN G ++G V + D + +I + R FS+ S G+ I T A DRE+ + + ++ + G + +++V + D N++ P F ++ Y +AE+ P+ + V A D D G NG++ Y + F +F G + V+ +DRE +E Y L + A+D+G PL+SSV +N+TV DVNDN P + F F + + + +G +Q D+D G N V +S P + + + G + + DRE R V D G Q V + V DVNDN P+ SVYQ+ +TQL+ V D D+ N L Y I N F+ +++TG ++L L Y + VS DSG+ PL
Sbjct: 356 AGSYVKDVTAMDADSGLNAKLRYSIVSGNDLGWFSVDESTGLVTTDGKVD-------REVAS---------SVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTK---YVATAVENSLPGLFVVSVSAADSDLG-ENGTVRYNFDPDMPAQYREMFRL---DSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQL--TAGDAARFQVNAVTGAVSTRVS--LDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNANVTYLIVSGDQ---RGSFSIEWSGGR--------IFTANAIDREEQAFYQLRVVANSGG-------VAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGIFP----DGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVG-SLVGAVQATDADAGSNGGVTYSFEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAK---------------------SVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINEGNE--GGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPL 1057 HSP 4 Score: 156.377 bits (394), Expect = 1.338e-38 Identity = 153/614 (24.92%), Postives = 262/614 (42.67%), Query Frame = 2
Query: 404 LSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAG----SHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN---DLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS-----PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKK--------------ILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL--FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENL--APATIGQLQYEDSDIGRNADVVFSKTWPNDDTVM-ITVNGTLYITKPLDRETKDRHCLRVRLRD 2149
LSG F +D S VL ++ +D E + L+ S G + R+ ++V D NDN P+FS+ V+E + G + I A D D P ++ Y LA S P LN LD E++ Y+++ RA + L V++ D NDN P + + V E+ P + + ++ A D D + + ++ + F+V +G + ++ LD ER Y + V V+D + L V + +P E+S G V+ V D D + + +E++L++ + +T ++R DRE ++ ++ D LTS+ T+ V + D NDN P+F + +Y A +AE+ P GT +L+++A+D D+G NG++ Y + F++D G + V P+DRE Y+L + A D G + + + +T+ DVND SP L+P+ REN P I Q+ D D+G + V ++ ND ++ +G +++ + LDRE + +H L + D
Sbjct: 1556 LSGSEGAFVVDAASGVLRASRRLDREERA-SYLLTVRASDGTHATD--------------ARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGP-FGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGGLAATARLYVNVL--DANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELE-FSISSGDPEGRFAVGNDGQ-LSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAPEDSPVGAVVATVQAVDPDSGRNS------------YVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVD----KGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGPARSDTASVRVTLSDVNDCSPAFQLSPYTVHARENTQGPPVLILQVVARDDDLGSSGQVTYAAAGGNDGGAFSVSPDGHVHLLRSLDREAQPQHVLIITATD 2133 HSP 5 Score: 155.221 bits (391), Expect = 2.780e-38 Identity = 158/571 (27.67%), Postives = 250/571 (43.78%), Query Frame = 2
Query: 914 VDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENS---GKG--LVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGK-NKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-----EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIP---LNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAP------ATIGQLQYEDSDIGRNADVVFSKTWPNDDT-----------VMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
V++ V+D NDNPP F + V+ENT +IF L A D D +++ + + + F V V+ S LD E Y + V +DG + + L V V D ND SP+ ++ +V E++ GK VIG V+ D D +G P + + G +T + DRE + + +DG +A L V +LD NDN P + A V E+ P GT +L+++A D D+G+N ++ +S+ E F++ G ++V +DRE + Y L + D P L+S+V +++ + DVNDN+P +P R LAP A + +Q D D GRN+ V ++ ++ + TV G + + + LDRE + + L V D G S+ + + V D NDN PR PR RE + A I+ + PG + +L A D D+ N +L Y I + P+ F + G L++ +PL Y + V +D G P
Sbjct: 1502 VEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGA----FVVDAASGVLRASRRLDREERASYLLTVRASDGTHATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDAD----SGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGGLAATARLY------VNVLDANDNAPSVQNDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAV----GNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSP-----RSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKG-RPPLTSTATLAVTVGDANDNAPRF--PR--REYEAA----------IAEDEPPGTEVLRLSAWDPDEGANGELRYDIASGD--PTGDFRLDPVLGTLAVARPLDRERTASYELAVRARDGGGP 2032 HSP 6 Score: 145.591 bits (366), Expect = 3.058e-35 Identity = 193/742 (26.01%), Postives = 301/742 (40.57%), Query Frame = 2
Query: 392 LIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEAS----HKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLL---NDLDAENQTHYLIKIRAW-NAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXX---XXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEP---RLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLT-PFEFSVRENLAPAT-IGQLQYEDSDIGRNADVV---------FSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
L+++ GP D K+ +++ + +D E+ R+ + + G N L I +LDVNDN P + AS G+ L T TD D N ++ + ++ L P L +L + LD E Y + I A N + + ++ +YV+D ND+ PRF S ++ + E PA S + + A D DS + LR+ + + N+L FSV ++ ++ +D E + + D + ++ L NDE P Q V +ENS GL + V D D + NG + + P R F L S LT + T + DRE+ + +V+ D + L S+ + V + D NDN P F QYFA + EN P GT + V A D D G NG + Y L D + FQ+++ TG ++ + +DRE + Y+L + A+D G + S + ITV D D P + F V EN+AP T +G + D+ N + FS W G ++ +DRE + + LRV G+ G V + V DVN++ P AS +SI+ + + A D D N ++ Y I N + F G L + L Y + VS D+G PL
Sbjct: 158 LLHRGRGP-LAVPFDPKTGMVSTRQPLDFEA---RRQYTLSLRAADG---------GNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSI--VSGNDL-GWFSVDESTGLVTTDGKVDREVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVVSVSAADSDLGE-NGTVRYNFDPDMPAQYREMFRLDS------LTGKVTTLKSLDREELEEYPLVVQAQD----RGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAARFQVNAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNANVTYLIVSGDQRGSFSIEW---------SGGRIFTANAIDREEQAFYQLRVVANSGGVAGE----ASVSVLVHDVNNHAPVFDR--------------ASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNG--GEKFGI-FPDGQLYVRYELDRETREEYSLTVSAMDTGVEPL 842 HSP 7 Score: 145.206 bits (365), Expect = 3.444e-35 Identity = 166/625 (26.56%), Postives = 279/625 (44.64%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHH--KSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTS----VLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG----LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKT-----AFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEF-SVRENLAPAT-IGQLQYEDSDIGRNADVVFS--KTWPNDDTVMI-TVNGTLYITKPLDRE-TKDRHCLRVRLRDNGL--NGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHI 2389
V + V DVN++ P F + E ++E S F ATD D +N +++Y + E + + F + D Q L++ +LD E + Y + + A + + + V++ V D NDN P FNSS + E S++ + A D D+ S F+ Q N EL + + V + + + V TDG + R+ ++V V+D ND PQ ++ V E++ + +V +D D+ NG L ++++ G T D T + DRE+++ ++V+ +D S L +S T+ VQ+LD NDNPP+F +S E+ +G +++ + A D D G +G + Y++ + + F ID +TG + + +D E + Y+L++ A D G P +S+ L + V D NDN P L F S+ EN+ T + + D D N ++ +S + +P I +G + +DRE T + VR D + + RR + V + V D NDN PR + P + + D AA G V+ L A D D+A N + Y +
Sbjct: 744 VSVLVHDVNNHAPVFDRASYEVSIAE-DEPVNSRFFSVRATDKDSG-KNGEVKYEIGEGNGGEKFGIFPDGQ----LYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQV-NFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEG-VNGA-----------LRYAINEGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATD----SGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAI--LVDGLRAAA------------GSVVGTLQASDPDEAENAAVRYAV 1331 HSP 8 Score: 140.198 bits (352), Expect = 1.218e-33 Identity = 149/543 (27.44%), Postives = 244/543 (44.94%), Query Frame = 2
Query: 572 LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLND---LDAENQTHYLIKIRAWNAQDNKQWNE-LNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPR--LEFSLSSGKNKKILTYDIRTKTAF-----DREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF---SLFQIDSTTGVITVQGPVDRELKEH-YKLHIHAVDSGSIPLNS--SVGLNIT--VDDVNDNSPCLLTPFEFSVR--ENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRET 2113
L + V V ++VLDVNDN P F+ H E + GS + ATD D A N + Y + +F+L + R L + + + + + A + K + V ++V D NDNPP+F S++ V E+ + + ++ A+D D LR+ + + NE K G + L+ S LD E Y + V TD A + V V DEND P+ ++ ++ +E++ +G++++T + E T P + +++ +G D T + F D E + + DG +S+ + V + DFNDNPP F FA + EN PIGT ++ V A D D +NG++HYS+ F + F ID +G I +DRE+ +++ + A D +IP+++ S N+T V D NDN+P +TP V A + +G LQ D D NA V ++ T D ++ ++ G + + LDRE+
Sbjct: 842 LSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCE-EQEVGSLVGAVQATDAD-AGSNGGVTYSFEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINE--GNEGGKFTVDASTGQITLLGS-LDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPRFTESLLSVDALEST----RVGELLIT----------LTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPP----RSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDK-AIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAILVDGLRAAAGSVVGTLQASDPDEAENAAVRYAVTG-GDAAILFRLDRRTGIIETSTELDRES 1359 HSP 9 Score: 139.813 bits (351), Expect = 1.506e-33 Identity = 156/581 (26.85%), Postives = 253/581 (43.55%), Query Frame = 2
Query: 830 LDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD--IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDREL------KEHYKLHIHAVDSGSI-PLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPP 2530
LD E + Y +++ A + + + V + V D D PP F +S +V EN +++ + A+ D + + Y + + R FS+ +G I ++ +D E Y++ V G + + VLV D N+ +P + + + E+ V TDKD S NG++ + E +G K + D + + DRE + S+ + D + L+SS T+NV +LD NDN P F S Y H E +G+++ V A D D G NG + YS E F++DS TG I DRE + + A D G PL + + V DVNDN P + ++ SV E+ + T + ++ D D G N + ++ N+ TV+ G + + LDRE + L V D+G + +S V ++V+D NDN PR L +D A +S + G ++ L A D+D + + Y I+ NT F+ + +TG + L + L Y + VS +D G PP
Sbjct: 616 LDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNANV---TYLIVSGDQRGSFSIEWSGGRIFTANAIDREEQAFYQLRVVANSGGVAGEASVSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKD-SGKNGEV---------KYEIGEGNGGEKFGIFPDGQLYVRYELDRETREEYSLTVSAMD----TGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVDEGVNGALRYAINEGNEGG-KFTVDASTGQITLLGSLDREETASYTLVVSATDSGTS-PLAASCTVAVQVLDENDNPPRFTE--SLLSVD------ALESTRV------GELLITLTASDEDTGPSGDVRYAIVAGNT--HATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPP 1161 HSP 10 Score: 116.701 bits (291), Expect = 1.763e-26 Identity = 100/340 (29.41%), Postives = 151/340 (44.41%), Query Frame = 2
Query: 1559 SSFT-INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYS-LEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLT-PFEFSVRENLAP------ATIGQLQYEDSDIGRNADVVFS------KTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREI-DDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPP 2530
SSF + + + D NDNPP F + V EN G VI ++A D D G N + YS L F +D+ +GV+ +DRE + Y L + A D + L++ V D NDNSP + F V E+ AP A IG + D+D G +V ++ W + + V G L +T+PLDRE++ + LR R D G ++ + + V+D NDN P + N E+ +DA PG + ++ A DDD+ N +L + I + P F+ + G LS+ + L Y + V V D P
Sbjct: 1497 SSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASRRLDREERASYLLTVRASDGTHA---TDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATD---GGGLAATARLYVNVLDANDNAPSVQNDSLAAEVPEDA---------------PPGTSLLRISATDDDEGVNAELEFSISSGD--PEGRFAVGN-DGQLSVARALDRERQSFYNLVVRVSDRARHP 1812 HSP 11 Score: 115.161 bits (287), Expect = 6.172e-26 Identity = 192/869 (22.09%), Postives = 345/869 (39.70%), Query Frame = 2
Query: 170 TVSYNYKLIFQQSGKMDILK---TLFLFLTAVRCSETGIKECVLKYLIQENEP-IDRMVGTIATDIEGLGINLEFHGSLIYKLSGPN--CCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELR--KLFSVLQNGTVILISSWLDYE-RHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPI----GTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQG---PVDRELKEHYKLHIHAV------------DSGS-----IPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMI-TVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQ-------IFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFIT----NKPAKYDDKLQS 2602
S+++ ++ G+ L+ T+ +F+ V + + V + + E+ + +++ A+D++ G+N G+L Y ++ N F++D + +T+ ++D E + S SG L A V + VLD NDN P+F++ + E S + G + TA+D D P + + Y + + +D+ +FL LD E Q Y + + A + + + + ++V DFNDNPP F + EN P + + + A DPD+ + +L+ + + F++ I ++ +D E ++V V TD ++ RS L+ + DE +P+ + +++ + G V+G + +D D+++ + ++++ G + D I T T DRE + + + +A + TI + FN P+F Q PI G I ++Y L + H E + L GV G P+D + + L + D+G+ P++S + I+V+DVNDN P P E V EN I L D+D G+NA V +S ++ ++ +G L ++ LDRE + + L VR D G + + + V D NDN PR R D A A + + VI ++A D D ++TY + PS+ F + TG L++ +PL Y ++ D G L Y+ + N P+ +D L +
Sbjct: 934 AASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLLRVTASDVD-EGVN----GALRYAINEGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTS------------PLAASCTVAVQVLDENDNPPRFTESLLSVDALE-STRVGELLITLTASDEDTGP-SGDVRYAIVAGNTHATFAIDRSTG-SVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDAD--VNGELHYSIARQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAILVDGLRAAAGSVVGTLQASDPDEAENAA------------VRYAVTGGDAAILFRLDRRTGIIETSTELDRESGHGAFTLEVVAVEAKAAAPRTQRAENTIIANSMTFNHPLPRFPQDY-------ESPINLLQGQTIPMPSSY-----LFLRHHLDWEPEGQLVFFTLLLGVTRGHGVINPLDAPWRVSFDLTARCMFIVFSSLLSSLRDNGAGSFIRPPMSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASRRLDREERASYLLTVRASD----GTHATDARLSVAVRDANDNSPRF--SRHAYSFDVAEDAAPDGKTTRA-------VIGTVLAGDADSGPFGEVTYAL-----APSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGGG--LAATARLYVNVLDANDNAPSVQNDSLAA 1736 HSP 12 Score: 79.7221 bits (195), Expect = 3.398e-15 Identity = 87/335 (25.97%), Postives = 132/335 (39.40%), Query Frame = 2
Query: 1571 INVQILDFNDNPPKFRQSQYF-AHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLE-----HDFSLFQIDSTTGV----ITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNG---LNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDAT-NTKLTYHILLPNTLPSQIFSFNSTTGY--LSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
+ V + D NDN P F + E+ +G +L A D D G NG H++ + + L T + GP+DRE Y L + A D GS + +N+TV D NDN P P + R ++A EDS +G + + G + +PLD E + ++ L +R D G L+GR I+++DVNDN P I P A++S S+ +PG V + D D T N +L+ I+ N + G L + L I Y + + D+G P
Sbjct: 9 VRVVVGDVNDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKP---AYRASVA---------EDSPVGAALRDLLHRGRGPLAVPFDPKTGMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGR----ATAVIQLLDVNDNDP---------AIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKP 318
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006996.1 (pep scaffold:Pmarinus_7.0:GL476780:2096:143714:1 gene:ENSPMAG00000006222.1 transcript:ENSPMAT00000006996.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 166.007 bits (419), Expect = 1.846e-41 Identity = 201/756 (26.59%), Postives = 326/756 (43.12%), Query Frame = 2
Query: 329 MVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESI------CINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGS--HIFLETATDTDIAPENAQIEYGL---AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIK--IRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD-STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG-----LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVV----LICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL--FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLA-PATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMIT--VNGTLYITKPLDRETKDRHCLRVRLRDNGLNG-RRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDK-PLSHHYIGHYPIKV 2503
+V +ATD++ G+ G + Y S + FS+D S ++++A +D E+ + R+ ++G RVRI++LDVNDN P F + + +V A S + ATD D +P N QI Y + + + F + + + L LD E I I A + + + + V D NDN P F+ + +S+ + EN A + + + A D D S + L + + F + I ++ LD E +Y + V DG + + + + D ND P P + ++EN+ G I V D D ++ NG ++ + P + +SGK + T DRE + IS ++ S S T+S T+ V + D NDN P F Y V E P + + +V A D D+G NG + YS+ FQ+D+ TG+IT +DRE Y+L + A D G+ L+S+ L++ V DVNDN+P S+ E++A + + L D+D G NA++ F T N D +G + LDRETK + L + DNG G RR + + + V+DVNDN+P + S +S+ + G +I Q+ A D D+ N ++ Y I+ N F N ++G +S PL + + ++V
Sbjct: 49 VVQVLATDLDA-GV----FGQVSYHFSDDSDKFSLDPASGLISVAAALDFEATPRFTVTVMARDGGGQETAG--------------------RVRINLLDVNDNTPVFQR---DSYVGTARENDNSLTPVVRVRATDED-SPPNNQITYSILPTSAYSSYFSITVSGGYG-VVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLEGSTQ--FRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNE-NGTLVYAIDPPNPFYRINAASGKIRT-------TGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPLFLE--------------GSYEVSVPENVTRGAIILQVQATDIDEGINGRVWYRIISGNQ--DGNFLVNVSSGLISRGATPLDRETVALHALQV 748 HSP 2 Score: 134.035 bits (336), Expect = 1.160e-31 Identity = 179/781 (22.92%), Postives = 331/781 (42.38%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSI---DQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENA-QIEYGLAE-HHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDL------------YQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---------LYEARSXXXXXXXXXXXXSPQL-IQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICE-HETTEPRL--EFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKF-RQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-LFQIDSTTGVITVQ--GPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFE-FSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPS---QIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
I EN P ++ + I + + +L Y L G + + + D+ + + + + +D E I G LEL + + + A VR+ ++VLDVNDN P F+ HV E S G+ + + A D D+ +A + Y +A + +F + + + + +D E + YL+ + A + + + + + D F+ + + + E +++ ++ A + L L ++ ++ +L + LQ I + LD E Y + V DG + + + V V DEND SP+ + +++EV E++ G ++ + TD+ D+ +NG + H T R+ ++ L + D+ K F + S I ++ DG + +++F ++V +LD NDN P F Y V E G GT++ V A D D G NG++ + +E I + G+I V +DRE + Y L + AVD G+ PL+ S + + VDDVND P L P + SV E+L+ + + ++ ++ G N + + + L + L ++ +R L D+G +G + + V+DVND++P + P + T ++ + + + I +++AVD D+ N + Y L + S + F N+T+G +S + L Y + + D G P
Sbjct: 1509 IPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNVSMALGQGLDREGIP------------GGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGNDTFGI---DESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVVVRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAELIAALQGE--ITTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDR-DAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDV-AKADFVEKTSQFILFRIVALDGGSPPR----STTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGGDKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNAFTVHATSGLVTSTRL-LKSYERFNLTAVATDHGRPPLWGQAG-LYVEVLDVNDHRPVFVLP------PNGTVVNITEVMPVVIR------IVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRESQAVYSLILLASDQGQP 2252 HSP 3 Score: 131.724 bits (330), Expect = 5.023e-31 Identity = 155/581 (26.68%), Postives = 252/581 (43.37%), Query Frame = 2
Query: 878 NAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREK--SSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLN-GKIH--YSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSS--VGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITK-PLDRET------KDRHCLRVRLRDNGLNGRRQ-SSGEVCIRVIDVNDNKPRLIN-PRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFI 2563
N + W V + + + NDN P F+ L++V V EN + + Q++A D D+ + + + +++ FS+ +I +++ LD+E R+ V V D G E + + + D ND +P ++ V EN + +V TD+D N T+ FS++ ++T A D EK IS+ ++ DG + N S+ T V++ D NDN P F ++ Y + EN G +L VNA D D G++ YSLE + F+I++ +G IT +DRE Y L + AVD G + +NIT+ DVNDN P P+ ++ EN T I + D D+ N +V++ PN + +G + T LDRE + V D G RR +S V + + DVNDN+P + P L+ ++ PA S + Q+ A D D+ N +TY + LP F ++ TG ++ L + Y +++ D G+P L L +
Sbjct: 4 NETSGEHWGSARVHITLINENDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLDAGVFGQVSYHFSDDSD---KFSLDPASGLISVAAALDFEATPRFTVTVMARDGGGQETAGRVRINLLDVNDNTPVFQRDSYVGTARENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGVVTL----ARALDYEKIPGGTISLTIMALDGGSPPLN----STVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLEGS-TQFRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAIDPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGL--PANS-------------TLFQVTATDPDEGANGNVTYS--MTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVV 555 HSP 4 Score: 117.857 bits (294), Expect = 8.989e-27 Identity = 133/513 (25.93%), Postives = 220/513 (42.88%), Query Frame = 2
Query: 389 SLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQL--CLDQQRQPYLFL----LNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQG-PVDRELKEHYKLHIHAVDSGSIPLNSSV 1876
SLIY L G + F I+ +S +T +D E++ + G G N Q + V I++LDVNDN P + + E + G+ IF +A D D+ EN + Y + + +++ + R L L LN + + ++ + + V + + D NDN P F +++ V E PA S +FQ+ A DPD + TA R F + +I LD E Y++ + TD A S L D +P S + +ME+ + V+ + TD D S N + L F ++ G + +RT + DRE + S+V+ D N A T + T++V +LD NDN P F + Y V EN G +IL+V A D+D+G+NG++ Y + + F ++ ++G+I+ P+DRE + L + A ++ S+ L+S +
Sbjct: 278 SLIYSLEG-STQFRINARSGDITSTTLLDREAVSQYILIVRAVDGGDG----------NDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENT-PGGTDIFTVSAADPDLN-ENGTLVYAIDPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALP-RPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDAD-SGLNAE-----------LSFFITGGNQDGQFSVGFRDGLVRTVVSLDRETKASYSLVIEAID--NGPAGSRRTGTTTLDVLVLDVNDNRPLFLEGSYEVSVPENVTRGAIILQVQATDIDEGINGRVWYRIISGNQDGNFLVNVSSGLISRGATPLDRETVALHALQVEAFNNDSVGLSSVI 762 HSP 5 Score: 99.7525 bits (247), Expect = 3.192e-21 Identity = 105/376 (27.93%), Postives = 169/376 (44.95%), Query Frame = 2
Query: 1304 SGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPV--DRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLT-PFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFS---KTWPNDDTVMI--TVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGR--RQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHIL 2392
S G+ + V +D D+ N +++ + F + +G +LT A D E S+ + ++++ + LTS+ T++V + D ND P F +S G G I A D D GLNG++ YS+ + F I G + V+ V DRE + Y L I A D G+ PLNS++ + + V DV+DN P L P S+ E A A + +++ D++ GRN + ++ N + + G +Y+ +PLDRE + L + +RDN N R+ S + + ++D NDN P EI + SP + ++V P Y A D D N L Y +L
Sbjct: 1186 STAGVAVANVTASDPDEGD-NARVVYAIVSGNTAATFGIDNGTG--VLT----AVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQPGPRIATFMASDQDSGLNGELEYSIIDGDPRNEFVISPADGDLRVRRYVELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPE-NSPNGT---VLTVLNGPIY------ASDADFGVNATLAYSLL 1544 HSP 6 Score: 93.5893 bits (231), Expect = 2.272e-19 Identity = 104/389 (26.74%), Postives = 175/389 (44.99%), Query Frame = 2
Query: 1409 EFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGP--IGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEH-YKLHIHAVDSGSIP---LNSSVGLNITVDDVNDNSPCLLTPFE--FSVRENLAPATIGQLQYEDSDIGRNADVVFS--KTWPNDDTVMITVNGTLYITK--PLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATN-TKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPP 2530
E +L+ + KI T R T ++++ S IC T+ T+S I +I D NDN P F + Y + E GP G + V A D D+G N ++ Y++ + + F ID+ TGV+T +D E+ Y L + A D P L S+ +++ V DVND +P L +E V E I D D G N ++ +S P ++ V+ +G L + + LDRET+ + L + +D G S+ V +RV+DV+DN P +N + +A + A +++++ A D ++ N L H + F +S TG + +++PL + Y + ++V+D+ P
Sbjct: 1110 EATLNKQASIKITTITQRLCTKVLVKRAASASTRGICL----TATPAQATTSVLI--RITDENDNAPAFGAATYEVLLTE-GPSTAGVAVANVTASDPDEGDNARVVYAIVSGNTAATFGIDNGTGVLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQPGPRIATFMASDQDSGLNGELEYSIIDGDPRNEFVISPADGDLRVRRYVELDRETQAFYNLTIMAKDMG-TPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLA--------------IVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNP 1476 HSP 7 Score: 93.2041 bits (230), Expect = 3.238e-19 Identity = 150/557 (26.93%), Postives = 239/557 (42.91%), Query Frame = 2
Query: 578 AVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAE-NQTHYLIKIRAWNAQDN---KQWNELNVDLYVDDFNDNPPRFNSSLFSVL-VKENTPARSMIFQLIANDPDSTSVLRFDL-YQTANNELRKLFSVLQNGTVILISSW--LDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXX--XSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAF-----DREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVN----AYDLDDGLNGKIHYSLEHDFSL-FQIDSTTGVITV---QGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPA---TIGQLQYEDSDIG--RNADVVFSKTWPNDDTVMITVNGTLYIT-KPLDRETKDRHCLRVRLRDNG 2155
A V I + D NDN P F E ++E AG + TA+D D +NA++ Y + + + +D L + LD E + YL+ + A + + + + V ++V D ND P F S + V E P I +A+D DS L +L Y + + R F + + + + LD E Y + + D G S L V V + P + P+ + E + ++ +V +D ++ + N + +H T S +G ++ D +T + DRE+ ++ + L D + + S I V ILD NDN P F Q Y A + EN P GTV+ +N A D D G+N + YSL S F ID G +++ QG +DRE +L + + N++V L +TV DVNDN+P +T V EN +PA ++ ++ D D+G V +S +DT I + L +T P+D ET+ + L V D
Sbjct: 1154 ATTSVLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEG-DNARVVYAIVSGNTAATFGIDNGTG-VLTAVKALDFEVSAGLYLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWFLRSYEGPIDVSEGQPG-PRIATFMASDQDSG--LNGELEYSIIDGDPRNEFVISPADGDLRVRRYVELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVSRVRASDANEGR-NCAALLQHSPT------SFCNG--ERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMI-VTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNVSMALGQG-LDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLEN-SPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGNDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQA 1693 HSP 8 Score: 81.2629 bits (199), Expect = 1.390e-15 Identity = 99/389 (25.45%), Postives = 167/389 (42.93%), Query Frame = 2
Query: 1286 IEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEH-DFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAV--DSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRE--NLAPATIG--QLQYEDSDIGRNADV---------VFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLI-AVDDDDATNTKLTYHILLPN 2401
+ V+E G ++ V TD D + NG++ E+ LS G + I+ + DRE + +++++ D N L+ S + V + D ND P F V E+ +G+ + V A + G N K Y + + F + +T+G++T R LK + + ++ AV D G PL GL + V DVND+ P + P +V + P I ++ D D G+N V V S+ W + + +G + + LDRE++ + L + D G +S+ + + + D++DN+P I + D +P QS SI + PG + + AVD D N + Y I N
Sbjct: 1961 VSVVELGAPGTLVASVWATDAD-AGPNGQVTFRIESGGGD---KLSIGPSDGIIR--VAPGANIDRETRAAYTLMVVAVD----RGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKNAFTVHATSGLVTST----RLLKSYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDW--ESFRINATSGIISTARALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFI------VLPDGGAP--YQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFIAAGN 2325 HSP 9 Score: 73.9442 bits (180), Expect = 2.491e-13 Identity = 182/815 (22.33%), Postives = 308/815 (37.79%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPY-------LFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVD---DFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVL------QNGTVILISSWLDYE--RHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKI----LTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDL--------------DDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGS----IPLNSSVG--LNITVDDVNDNSPCLLTPFE------FSVRENLAPAT-IGQLQYEDSDIGRNADVVF------SKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNG---RRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSL--DKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFI 2563
+ E +P R+ +A+D + G+N E S+I P F I L + + ++L+ RE + +L ++ L + + V + VLDV+DN P F +SEA+ L + + N H C + +R Y +++ LD E Y + + + DN + + D+ + D NDN P F+ + + EN+P +++ L N P S F + T L S + + + LD E R ++ + V D G A L V V D ND +P V+ENS +G ++ K + G +C+ T + +S++SG N T I T D E + ++++ +D A T+S + V + + D F + Y A ++E GTV+++V A + K H E D + I + G IT Q +DRE + Y L + + D G L + G + + V D NDNSP FE VRE+ AP T + L D D G N V P ++I + I + ++ + R L+G R ++ + + V+DVNDN P ++P G ++S+ +PG ++ + A D D N ++T+ I + S + G + + + Y + V D G+PPL + + +
Sbjct: 1292 VSEGQPGPRIATFMASDQDS-GLNGELEYSIID--GDPRNEFVISPADGDLRVRRYVELD-----RE-----TQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAA------AVLAIVSRVRASDANEGRNCAALLQHSPTSFC-NGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVL--NGPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPA---VGTSVIVVKAMDRDLG--VCDAGT----VRYSIASGGNDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATD----QAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVVVRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAEL-IAALQGEITTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSP----EFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGY-------------AVSVVELGAPGTLVASVWATDADAGPNGQVTFRI---ESGGGDKLSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLV 2050
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004043.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004043.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 158.688 bits (400), Expect = 3.379e-39 Identity = 154/553 (27.85%), Postives = 249/553 (45.03%), Query Frame = 2
Query: 596 ISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFV---TDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKI--LTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDT----VMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDN 2218
ISV + N P+F+ +E + E +H AGS + TATDTD A N I Y +A S + + L L+ +LD E + Y + + A + + V + V D NDNPP N+S + ++ EN P+ + + + A D DS S +Y + E LF + Q V+ +LDYE Q Y++ V D + + + + V + N+ P+ +Q V E++ G +G V TD+D + +G + + F S K + T +I + DRE+ + ++ +I + + +NV I D ND PP F + Y V+E +GT ++ V+A+D D + L + F I++ TG+I V P+DRE Y L + AVD G P + + + ++DVNDN P LLT A T+ L+ D D+ N + +D ++ +G L +P+DRE K L V + D G + S+ + + V+D NDN
Sbjct: 743 ISVTEENQYAPRFAHPPLELSLPE-NHPAGSSLARVTATDTD-AGVNGAIVYSIASGDGSGLFDISRASGDVL-LVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNA-VTMYSLDDGEA-DLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRD-AGIDGTVF--------YMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRG--FDVDEVLVNVAITDAND-PPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLLTSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAG-SPPLTSTVTLHLSVLDQNDN 1277 HSP 2 Score: 157.147 bits (396), Expect = 8.318e-39 Identity = 177/680 (26.03%), Postives = 288/680 (42.35%), Query Frame = 2
Query: 569 QLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL--AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQW-NELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS--PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKN-KKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPL---------SHHYIGHYPIKVSVKDSGSPPL 2533
+L V + V D NDN+P+F + V E + GS + L ATD D A NA I Y L + H S Q + LD E + Y++++ A + + + + V D ND+ PRF ++ + + PA + +F + A D D+ LRF L +A+ FSV VI + L R + V V+DG RS + + D P+ P E+ G I V S+ G + + L+SG N + D + A D E +V+ D S ++ + V +LD NDN P+F S+++A V EN P T+++ + A D D G+NG++ YS+ + ++F+++ +G I +DRE Y+L + A D GS + +V + I+V D NDNSP F VRE+ A + ++ D+D G NA + FS P+ + G + +++ L+RE + + ++VR D S +V I V DVNDN PR E + P+ +++ + ++ A D DD N ++ + + ++ F +G + +PL S + Y V+ D G PPL
Sbjct: 5 RLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDA-PIGSDVALVNATDAD-AGLNAIISYRLRGGDGHFSVNPSTGQ-----IITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSAS----AGFSVDPRRGVIHAARALQGPRDD-LTLTVRVSDGGAPPRSAVTTVTVRFRDAGEFPRFAPGPRSFSFREDQPPGTTI---TVVAARSSRRAGP-----------VSYHLASGGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARD----SGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVV-LTAVDKDSGINGQVDYSIIDGNIGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPSLPFSIHPSTGEITVSRRLNREDRSGYAVKVRASDPAWT----VSTDVTIVVDDVNDNAPRFGQTAYYIEFPE---PSEGEAL-----------VARVSASDADDGANGQVFFFM----RSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPL 631 HSP 3 Score: 142.124 bits (357), Expect = 3.997e-34 Identity = 169/687 (24.60%), Postives = 298/687 (43.38%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSN--VQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKS-SQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVREN-LAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTV--MITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLS 2452
F++D +S +++ + +D E Q H EL+V + A +++ + VLD+NDN P+FS R V E + I + TA D D N Q++Y + + + ++ + ++ LD EN Y + ++A + Q + V + V D NDN PRF + +FS V+E+ + ++ D D + + F L + FS+ + I +S L+ E Y V V +D + + + ++V+D ND +P+ Q IE E S ++ +V +D DD NG++ + SG+ + R + ++ S V+ D L+S T+ + I+ N N P+F + +Y VA GT IL ++A D D +NG+I YS+ + F +D+ G + ++ + + + + + A D G PL+S I+V + N +P P E S+ EN A +++ ++ D+D G N +V+S + + + +G + + LD ET+ + L V D G + + SG V I V DVNDN P ++N + +P+ G + + AVD D +N Y + + + +F N TG L+
Sbjct: 279 FAVDPQSGEVSVHRALDHEY--------------QHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPP--RTIVVLTAVDKDSG-INGQVDYSIIDGNIGNVFRVNPNSG-EIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRF-TQIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPS-----LPFSIHPSTGEITVSRRLNREDRSGYAVKVRASDPAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDG-ANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMD----RGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNASRRFDVDA-GGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSG-VSISVTDVNDNPP-MLNASDYYPVIPENAPS-------------GTTVLVMDAVDADSPSNAVTMYSL---DDGEADLFVLNQKTGVLT 917 HSP 4 Score: 127.487 bits (319), Expect = 1.068e-29 Identity = 166/675 (24.59%), Postives = 292/675 (43.26%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEAR---SXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPL--NSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPAT--IGQLQYE-DSDIGRNADVVFSKTWPNDDTVMITVN-GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGE--VCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNT-KLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
V I+++ N N P+F ++R V+ A+ +AG+ I +A D D N QI Y + + S + +D +L L L + + + + + A + + + V + N PRF + + EN PA S + ++ A D D+ V +Y A+ + LF + + +L+ LDYE + Y + V DG ++A+ S + + V D ND P L + + EN+ G + + D D S +N + + E L F L N+K + ++ +++ +++V +N H +++ ++VQI N+ P+F Q +Y V+E+ P+G + V A D D G++G + Y L E F ++ TG I V +DRE + L + A ++GSI V +N+ + D ND + V E + T +G ++ DS G ++ I + G + + PLDRE+ + L V D G ++G V + + DVNDN P L+ + S ++ Q G + L A D D N T+ +L + FS S++G L +P+ + + V++ D+GSPPL +L + ++
Sbjct: 637 VTINIVVPNANAPRFLRERYSTPVA-ATVRAGTRILDMSAVDPDRD-VNGQIAYSVVGGNASRRFDVDAGG--FLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTDA-GVNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDAD-SPSNAVTMYSLDDGEADL-FVL----NQKTGVLTTQGFLDYETKQTYELTV-----RAFNYPDTFHYSTA-QVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDANDPPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMG---EPPATGTTVVVVALEDVNDNGPFLL----------------TSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSL-SSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQ 1274 HSP 5 Score: 110.153 bits (274), Expect = 2.139e-24 Identity = 144/583 (24.70%), Postives = 225/583 (38.59%), Query Frame = 2
Query: 830 LDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSD-GWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKE---------HYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-----TPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVM-ITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSG 2521
LD E Q HY + + A ++ L +++ V D NDN P F+SS F V ENTP R+++ L A D DS + D Y + + +F V N I S LD E Y++ V TD + ++ DE SP+ Q S V E++ G + +V D D+ +P L FS+ T +I +RE S +V + SD W S ++ + + D NDN P+F Q+ Y+ E ++ +V+A D DDG NG++ + + F++ +G I P+ Y + A+D G PL+S + I + N N+P L TP +VR A I + D D N + +S N + G L++ L + + V RD G S I V + N PR +P +S+ G + ++ A D D N + Y I + S +F + +G + L L + Y + V D G
Sbjct: 294 LDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVV-LTAVDKDSGINGQVD-YSIIDGNIGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQIFSA-HVREDAAVGFPVLRVSTLDADEGP---NAAITFSLLDPSLPFSIHPS------TGEITVSRRLNREDRSGYAVKVRASDPAWTVSTDV--------TIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVR---AGTRILDMSAVDPDRDVNGQIAYSVVGGNASRRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRG-RPPLSSRATAIISVTEENQYAPRFAHP--------------PLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDG--SGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGG 836 HSP 6 Score: 80.4925 bits (197), Expect = 2.374e-15 Identity = 115/502 (22.91%), Postives = 212/502 (42.23%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLL--AVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQW--NELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXX----XSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEP--RLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQ----YFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNI 1888
F ++QK+ VLT +D E+ + EL V ++ + +V + + VN+ P+F ++ VSE S G+ + ATD D A + + Y L +S +++ + + + LD E + +++ A NA + + +E+ V++ + D ND PP F+S+L+ V E + + + A+D DS R + + + FS+ + +I+++S LD E Y + V D + E + +V + P L+ S +V EN G+ + + D D G + ++P R FSLSS + ++T DRE+ + + + +D + + LTS+ T+++ +LD NDNP + R + YF G IG V + D+ D N + F++F T + Q R + ++L + D P ++ +N
Sbjct: 907 FVLNQKTGVLTTQGFLDYET--------------KQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSE-SAPVGAPVGSVFATDRD-AGIDGTVFYMLFGESRSKGFSVNEHTG-EIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVD-MGEPPATGTTVVVVALEDVNDNGPFLLT--SSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSS-------SGLLKTARPIDREQKPEFHLPVAIAD----AGSPPLTSTVTLHLSVLDQNDNPSEARDVRVHVNYFGSPFPGGFIGDV--RPRDPDISDRFNCDL---TSGPFNVFSFQPNTCRLISQ---PRSAEGRFELSVRGSDGKHSPATTTARVNF 1368
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004042.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 158.303 bits (399), Expect = 3.596e-39 Identity = 154/553 (27.85%), Postives = 249/553 (45.03%), Query Frame = 2
Query: 596 ISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFV---TDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKI--LTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDT----VMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDN 2218
ISV + N P+F+ +E + E +H AGS + TATDTD A N I Y +A S + + L L+ +LD E + Y + + A + + V + V D NDNPP N+S + ++ EN P+ + + + A D DS S +Y + E LF + Q V+ +LDYE Q Y++ V D + + + + V + N+ P+ +Q V E++ G +G V TD+D + +G + + F S K + T +I + DRE+ + ++ +I + + +NV I D ND PP F + Y V+E +GT ++ V+A+D D + L + F I++ TG+I V P+DRE Y L + AVD G P + + + ++DVNDN P LLT A T+ L+ D D+ N + +D ++ +G L +P+DRE K L V + D G + S+ + + V+D NDN
Sbjct: 743 ISVTEENQYAPRFAHPPLELSLPE-NHPAGSSLARVTATDTD-AGVNGAIVYSIASGDGSGLFDISRASGDVL-LVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNA-VTMYSLDDGEA-DLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRD-AGIDGTVF--------YMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRG--FDVDEVLVNVAITDAND-PPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLLTSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSSSGLLKTARPIDREQKPEFHLPVAIADAG-SPPLTSTVTLHLSVLDQNDN 1277 HSP 2 Score: 157.147 bits (396), Expect = 9.637e-39 Identity = 177/680 (26.03%), Postives = 288/680 (42.35%), Query Frame = 2
Query: 569 QLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL--AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQW-NELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS--PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKN-KKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPL---------SHHYIGHYPIKVSVKDSGSPPL 2533
+L V + V D NDN+P+F + V E + GS + L ATD D A NA I Y L + H S Q + LD E + Y++++ A + + + + V D ND+ PRF ++ + + PA + +F + A D D+ LRF L +A+ FSV VI + L R + V V+DG RS + + D P+ P E+ G I V S+ G + + L+SG N + D + A D E +V+ D S ++ + V +LD NDN P+F S+++A V EN P T+++ + A D D G+NG++ YS+ + ++F+++ +G I +DRE Y+L + A D GS + +V + I+V D NDNSP F VRE+ A + ++ D+D G NA + FS P+ + G + +++ L+RE + + ++VR D S +V I V DVNDN PR E + P+ +++ + ++ A D DD N ++ + + ++ F +G + +PL S + Y V+ D G PPL
Sbjct: 5 RLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDA-PIGSDVALVNATDAD-AGLNAIISYRLRGGDGHFSVNPSTGQ-----IITTASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAVFAVTARDADAGPNGDLRFSLSGSAS----AGFSVDPRRGVIHAARALQGPRDD-LTLTVRVSDGGAPPRSAVTTVTVRFRDAGEFPRFAPGPRSFSFREDQPPGTTI---TVVAARSSRRAGP-----------VSYHLASGGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARD----SGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVV-LTAVDKDSGINGQVDYSIIDGNIGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPSLPFSIHPSTGEITVSRRLNREDRSGYAVKVRASDPAWT----VSTDVTIVVDDVNDNAPRFGQTAYYIEFPE---PSEGEAL-----------VARVSASDADDGANGQVFFFM----RSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPL 631 HSP 3 Score: 141.739 bits (356), Expect = 4.215e-34 Identity = 172/704 (24.43%), Postives = 303/704 (43.04%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSN--VQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKS-SQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVREN-LAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTV--MITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKV 2503
F++D +S +++ + +D E Q H EL+V + A +++ + VLD+NDN P+FS R V E + I + TA D D N Q++Y + + + ++ + ++ LD EN Y + ++A + Q + V + V D NDN PRF + +FS V+E+ + ++ D D + + F L + FS+ + I +S L+ E Y V V +D + + + ++V+D ND +P+ Q IE E S ++ +V +D DD NG++ + SG+ + R + ++ S V+ D L+S T+ + I+ N N P+F + +Y VA GT IL ++A D D +NG+I YS+ + F +D+ G + ++ + + + + + A D G PL+S I+V + N +P P E S+ EN A +++ ++ D+D G N +V+S + + + +G + + LD ET+ + L V D G + + SG V I V DVNDN P ++N + +P+ G + + AVD D +N Y + + + +F N TG L+ L + Y + V
Sbjct: 279 FAVDPQSGEVSVHRALDHEY--------------QHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPP--RTIVVLTAVDKDSG-INGQVDYSIIDGNIGNVFRVNPNSG-EIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRF-TQIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPS-----LPFSIHPSTGEITVSRRLNREDRSGYAVKVRASDPAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDG-ANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMD----RGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNASRRFDVDA-GGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSG-VSISVTDVNDNPP-MLNASDYYPVIPENAPS-------------GTTVLVMDAVDADSPSNAVTMYSL---DDGEADLFVLNQKTGVLTTQGFLDYETKQTYELTV 934 HSP 4 Score: 127.102 bits (318), Expect = 1.257e-29 Identity = 166/675 (24.59%), Postives = 292/675 (43.26%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEAR---SXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPL--NSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPAT--IGQLQYE-DSDIGRNADVVFSKTWPNDDTVMITVN-GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGE--VCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNT-KLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
V I+++ N N P+F ++R V+ A+ +AG+ I +A D D N QI Y + + S + +D +L L L + + + + + A + + + V + N PRF + + EN PA S + ++ A D D+ V +Y A+ + LF + + +L+ LDYE + Y + V DG ++A+ S + + V D ND P L + + EN+ G + + D D S +N + + E L F L N+K + ++ +++ +++V +N H +++ ++VQI N+ P+F Q +Y V+E+ P+G + V A D D G++G + Y L E F ++ TG I V +DRE + L + A ++GSI V +N+ + D ND + V E + T +G ++ DS G ++ I + G + + PLDRE+ + L V D G ++G V + + DVNDN P L+ + S ++ Q G + L A D D N T+ +L + FS S++G L +P+ + + V++ D+GSPPL +L + ++
Sbjct: 637 VTINIVVPNANAPRFLRERYSTPVA-ATVRAGTRILDMSAVDPDRD-VNGQIAYSVVGGNASRRFDVDAGG--FLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTDA-GVNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDAD-SPSNAVTMYSLDDGEADL-FVL----NQKTGVLTTQGFLDYETKQTYELTV-----RAFNYPDTFHYSTA-QVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDANDPPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMG---EPPATGTTVVVVALEDVNDNGPFLL----------------TSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSL-SSSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLDQ 1274 HSP 5 Score: 109.768 bits (273), Expect = 2.352e-24 Identity = 144/583 (24.70%), Postives = 225/583 (38.59%), Query Frame = 2
Query: 830 LDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSD-GWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKE---------HYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-----TPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVM-ITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSG 2521
LD E Q HY + + A ++ L +++ V D NDN P F+SS F V ENTP R+++ L A D DS + D Y + + +F V N I S LD E Y++ V TD + ++ DE SP+ Q S V E++ G + +V D D+ +P L FS+ T +I +RE S +V + SD W S ++ + + D NDN P+F Q+ Y+ E ++ +V+A D DDG NG++ + + F++ +G I P+ Y + A+D G PL+S + I + N N+P L TP +VR A I + D D N + +S N + G L++ L + + V RD G S I V + N PR +P +S+ G + ++ A D D N + Y I + S +F + +G + L L + Y + V D G
Sbjct: 294 LDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVV-LTAVDKDSGINGQVD-YSIIDGNIGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQIFSA-HVREDAAVGFPVLRVSTLDADEGP---NAAITFSLLDPSLPFSIHPS------TGEITVSRRLNREDRSGYAVKVRASDPAWTVSTDV--------TIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFMRSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVR---AGTRILDMSAVDPDRDVNGQIAYSVVGGNASRRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRG-RPPLSSRATAIISVTEENQYAPRFAHP--------------PLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDG--SGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGG 836 HSP 6 Score: 80.1073 bits (196), Expect = 2.721e-15 Identity = 115/502 (22.91%), Postives = 212/502 (42.23%), Query Frame = 2
Query: 425 FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLL--AVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQW--NELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXX----XSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEP--RLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQ----YFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNI 1888
F ++QK+ VLT +D E+ + EL V ++ + +V + + VN+ P+F ++ VSE S G+ + ATD D A + + Y L +S +++ + + + LD E + +++ A NA + + +E+ V++ + D ND PP F+S+L+ V E + + + A+D DS R + + + FS+ + +I+++S LD E Y + V D + E + +V + P L+ S +V EN G+ + + D D G + ++P R FSLSS + ++T DRE+ + + + +D + + LTS+ T+++ +LD NDNP + R + YF G IG V + D+ D N + F++F T + Q R + ++L + D P ++ +N
Sbjct: 907 FVLNQKTGVLTTQGFLDYET--------------KQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSE-SAPVGAPVGSVFATDRD-AGIDGTVFYMLFGESRSKGFSVNEHTG-EIIVSSQLDREREASATLRVIAKNAGSIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVD-MGEPPATGTTVVVVALEDVNDNGPFLLT--SSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRGYFSLSS-------SGLLKTARPIDREQKPEFHLPVAIAD----AGSPPLTSTVTLHLSVLDQNDNPSEARDVRVHVNYFGSPFPGGFIGDV--RPRDPDISDRFNCDL---TSGPFNVFSFQPNTCRLISQ---PRSAEGRFELSVRGSDGKHSPATTTARVNF 1368
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 206.068 bits (523), Expect = 1.044e-53 Identity = 187/631 (29.64%), Postives = 300/631 (47.54%), Query Frame = 2
Query: 383 HGSLIYKLSGPN--CCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKS-FQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL 2230
+G + Y + N F ID + +T+ +D E++ S SG V W + +A I+V D NDN P F+ + E GS + + TATD D NAQ+ Y + S F + L + +++ E Y + IRA + ++ + + V+D NDNPP FNS + V+EN+ + + + A+D D + +VLR+ + + N+E R F + VI+ ++ LD+E +Y + V TD Y A++ + + V + ND +P Q V ENS + +V +D+D + L +S+ GK+ + D I T DRE S ++ + +D + N L++ + ++ILD NDN PKF S Y + + EN + K+ A D D+G N +I Y+L + F I +++GVIT+ P+DRE K Y L I A D G+ P SS+ + +TV D+ND+ P + + SVREN T + ++ D+D G NA++ FS N+ + T++ G + PLDRE + + LR+ + D G N S +V I VID +DN PR
Sbjct: 1235 NGRVTYSIISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSG-------VPPWVSTAFVA-----ITVADENDNSPIFASNETSYGIDEGV-SIGSRVAVVTATDRDEG-SNAQVFYSIVRGDTSAFAI---NAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSII-SGNDEKR--FKINSTSGVIMTTTPLDFEEKSQYGLEVTATDSKYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFGS--------------LSYSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTD----AGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSRN-DAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFS-LLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKG-NPSLSSVADVIIDVIDEDDNCPRF 1824 HSP 2 Score: 202.601 bits (514), Expect = 1.361e-52 Identity = 207/758 (27.31%), Postives = 339/758 (44.72%), Query Frame = 2
Query: 317 PIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNC--CFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRT-----KTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEF-SVRENLAPAT-IGQLQYEDSD--------IGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
P ++G+ + ++ G L Y+L N F+ID S + ++ +D RE + S L++ + + RV I++ D+NDN P F + R VSE+S G I ATD D + N + Y L+++ F + + L LD E +T Y++ + A + + + V + VDD NDNPP+F SL++ V EN A + + A D DS + + + NE F++ + I LD E Y + + DG + A + + + + DEND P PS + E+S G +GQ+ TD+D NG + +++ SG D R+ ++ DRE ++V+ SD + +I + +I+V +LD NDN P+F +S + + E+ + + +L+V D D+G NG I SL + S F IDS TG + + P+D E Y+L + A D GS +++ + IT+ +VNDN P ++P + S+ E++A T + +L DSD + NA F + +G + + K LDRET + L VR + G G + IRV+DVNDN P + NP S + S+ G + ++ A D D+ N K+TY + + +T F N TG ++ +PL Y ++V+ D G P
Sbjct: 488 PESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELD-------RETTPSYS-----LQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFR-VSESSSP-GHQIGQVAATDADDS-SNGDVRYALSDNTDVFSI---NTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNE-NMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFT-GPSRFNISEDSPTGTRVGQLTATDRDIGP-NGAVT-----------YAIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSI----TASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSDNFTIDS-TGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTPLTFDIVEGNAGSSFK---------IDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYN-NATIRVLDVNDNAP-VFNP-------------GSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDT---SKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKP 1181 HSP 3 Score: 192.2 bits (487), Expect = 1.913e-49 Identity = 216/762 (28.35%), Postives = 324/762 (42.52%), Query Frame = 2
Query: 293 KYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNC--CFSIDQKSSVLTIAKNIDLESICINREL--SSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSH-IFLETATDTDIAPENAQIEYGLA-EHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSX---XXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKI----LTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLT-PFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMI-TVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQL-IAVDDDD-ATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDS 2518
++ I E+ P VG + +G N G++ Y + N F +D +S +L++ +D E+I + +SD S Q + + +SVLDVNDN P+F K + E A H L+ + N I L+ E +F + ++ LD E Y + + A + + V + + + NDN P F S + E+ + + +L A D D T L FD+ + F + Q+ +I ++ LD E Y + V T+ + SV + V D ND +P + EN G + +V TD+D+ + N K+ E LS G K T + TK DRE + S+ + D S + + TIN D NDN P+F QS+Y V EN G+ IL+V A D D G NG++ YS+ + + F+IDSTTG ITV G VDRE Y L I A DSG P S+ + ITV D NDNSP + + + E ++ + + + D D G NA V +S + I +NG L + K ++RET + L +R D G + S E+ + V DVNDN P SQS SV ++ + L +A DD D N L Y I+ N + F NST+G + PL Y ++V+ DS
Sbjct: 795 RFNISEDSPTGTRVGQLTATDRDIGPN----GAVTYAIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSI--------------TASIHVSVLDVNDNAPRFEKSLFSGEIRE---DASVHSTVLQVKVEDKDEGSNGAITLSLSGEGSDNFTI----DSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTP-LTFDIVE---GNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGE-NAKVTYE-----------LSVGDTSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTIN----DLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRG-SPMMTSDKELTVVVNDVNDNPPVF----------------NSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGN--DEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS 1492 HSP 4 Score: 186.037 bits (471), Expect = 1.654e-47 Identity = 205/750 (27.33%), Postives = 325/750 (43.33%), Query Frame = 2
Query: 323 DRMVGTIATDIEGLGINLEFHGSLIYKL-SGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTS--VLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEAR---SXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDDT--VMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
D VG+I + + +++ + L Y L SG F++D + + T +RE + + L + V I +LDVNDN P FS + V E G+ + TA+D D NA + Y + + LD + + LD E ++ Y + + + + ++ + V+D NDNPP F+ S + VKENTPA + Q+ A D DS++ L F + + N++ +F++ + +I I+ DYE RY + V D + + + + +ED ND SP + ++ E++ G + V TD D RLE+ L SG K D IR + DRE + S+ + D + +SS + + + D NDN P F Q Y V+E+ G I +V A D DD NG + Y+L + +F I+++TG+IT++ +D E K Y + + A D G+ +S + + VDDVNDN P + +V ENLA + + D+D G N + +S N++ M G + PLDRET + L + D L R ++ V I + D NDN+P P +D SP ++ + QL A D D N +TY I+ N S F + +G LS+ L I Y + V D+GSP
Sbjct: 180 DVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDSQGVIRTKG--------AFDRETKASY-----QVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDE-DVAIGAAMVTVTASDKDNG-NNADLRYSFTSGNTNHAFTLDAVTG-VVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QVSATDRDSSTNGALVFGIIK-GNDD--GVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGP------------RGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARD----GGSTSRSSSTRVTIALQDINDNSPIF-QGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLV-RFMAATTVNISIADENDNQPTFTGPSRFNISED--SPTGTR-------------VGQLTATDRDIGPNGAVTYAIISGNQGNS--FQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSP 872 HSP 5 Score: 182.57 bits (462), Expect = 1.899e-46 Identity = 215/830 (25.90%), Postives = 364/830 (43.86%), Query Frame = 2
Query: 194 IFQQSGKMDILKTLFLFLTA-----VRCSETGIK------ECVLKYL-----------------IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLS-GPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQ--LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL--AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTS-------VLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVI-EVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPATIG-QLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
I Q SG + + K L TA VR +ETG + ++ L + EN PI + V + G N + + Y+LS G F ++ + ++T + +D E Q L V + + AV + +++ D+NDN PQFS+ + V+E + GS+I A+D D A N ++ Y + H +F++ R + ++ +D E Y + I A ++ + V + V D NDN P F S+ S + E S + + A D D S ++R D A N + + +V + + ++ R P+ +D +V ++ +++P + + S I V ENS + V+ DDS + L +S+ SG ++K + I T T D E+ SQ + + +D T+ + +++++ ND P F Q Y A V EN P T ++KV+A D D G + YS+ D F ID +G+I+ +DREL Y + + D+G+ PL++ + I + D NDNSP + + S+ EN AP++ +L D+D G NA + ++ + ND ++ +G + + +PLDRE K + L ++ RD+G + SS + + VID+ND++P LIN LR S+ Q + +++A D D N +LT+ LL N S +F+ ++TTG +S PL Y +++ V D G+P L
Sbjct: 1044 IDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAK----VTYELSVGDTSKFEVNPATGLVTTKRPLDRED--------------QASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTAN-GSNILRVLASDPD-AGANGRVTYSIISGNHGNAFRIDSTTGR---ITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSD-------KELTVVVNDVNDNPPVFNSQSYIGSVRENSAQST---SVLTVAADDSDVGANAV---------LRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS-------KYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSF--GSLSYSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLSR-NDAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHG-TPPQASSITIRVTVIDINDHRP-LINSSSLRG-------------SVRENQPKETHVMRILASDADTGLNAELTFS-LLSNEHKS-VFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSL 1804 HSP 6 Score: 172.555 bits (436), Expect = 2.217e-43 Identity = 192/662 (29.00%), Postives = 290/662 (43.81%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS---PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLN-SSVGLNITVDDVNDNSPCLLTPFEFSVR---ENLAPATIGQLQYEDSDIGRNADVVFSKTWPN-DDTVMITVN-GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
V I V D NDN P+F ++ E + A + + TATD D + NA I Y L F + + + + LD E + Y ++I A+ D K + + + VDD NDN P F S++ V E+ S++ QL A D D R + + F+V G VI D E Y+V + DG +RS + + D + P V E+ G + V +DKD NG L +S +SG T D + + D E+ S ++ L +D S + TS INV D NDNPP F S Y + V EN P GT +V+A D D NG + + + +D +F ID +TG+I++ D E K Y L + A D G +P+ + + I ++DVND+SP + +P +S + + +T+ + D D G + + N I N G++ ++ LDRET + L+V RD + R SS V I + D+NDN P P R +S SPG+ I Q+ A D DD++N + Y L NT +FS N++TG ++L L + Y + V+ KD G+P
Sbjct: 56 VVIDVKDENDNAPEFPLNSYVFNIRENTPAA--QVAIVTATDRD-SGTNAAITYSLFSGENKFMM---NSKTGEIRTVTPLDHETKDSYTMRISAF---DGKHTTFVPL-ITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDT--SYFTVDSQG-VIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKD----NGN--------NADLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRG--SPPLTDTSHLLINVN--DINDNPPVFSPSAYQSRVKENTPAGT---QVSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRG-VPVKYDTAQVTIFIEDVNDHSP-VFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDG-GSTSRSSSTRVTIALQDINDNSPIFQGPYVFR---------------VSESSSPGHQIGQVAATDADDSSNGDVRYA-LSDNT---DVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTP 663 HSP 7 Score: 172.17 bits (435), Expect = 3.015e-43 Identity = 179/654 (27.37%), Postives = 290/654 (44.34%), Query Frame = 2
Query: 596 ISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXSPQLIQNPSVIE--VMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSD-GWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKD 2515
I+V DVNDN P F+ + V E GS + TA D D+ NA++ Y L S+ +D Q + D E + Y + +RA + + + V++ + D NDN P F+S+ ++ V E+ + + + A+D D+ + LR+ N L +V V+ +S LD+E+ Y + + VTD G +L+ + + +PS + V EN+ G QV TD+D S TNG ++ F + G + + T D I + D E ++ + + D G + T+ TI ++ D ND+ P F S Y + E+ IG+ ++ V A DLD G G++ Y L + F ID+ +G I V +DRE Y L + A D GS +SS + I + D+NDNSP P+ F V E+ +P IGQ+ D+D N DV ++ + D + T G + + LD E K ++ + V +D G R S V + V DVNDN P+ + + ++ + G + + A D D N K++Y IL N + F+ + TG ++ PL I Y + ++ D
Sbjct: 156 ITVDDVNDNAPFFALSVYKTGVYE-DVAVGSIVRQLTAVDLDVGI-NARLSYSLVSGDTSY-FTVDSQG--VIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTG---VVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QVSATDRD-SSTNGALV-----------FGIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVK---YDTAQVTIFIE--DVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGG-TPSRSSLTVVKVMVDDVNDNPPQFAK--------------SLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGN--ENMAFAMDRFTGEITTRVPLDRETIASYSLTINADD 764 HSP 8 Score: 166.392 bits (420), Expect = 1.958e-41 Identity = 168/603 (27.86%), Postives = 267/603 (44.28%), Query Frame = 2
Query: 749 YGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRF--NSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS--LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGT---LYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKD 2515
Y + + + +D D E+++ Y + + A +A + V + V D NDN P F NS +F+ ++ENTPA + + + A D DS + + + L+ N K + G + ++ LD+E Y + + DG + V + V+D ND +P + V E+ G ++ Q+ D D RL +SL SG + T D IRTK AFDRE + V L DG + S + T+ ++ILD NDN P F +QY A V E+ IG ++ V A D D+G N + YS + F +D+ TGV+TV +D E + Y L + D GS PL + L I V+D+NDN P + ++ V+EN T Q+ D D N +VF NDD V T++G+ + I K D E K R+ L V+ RD G+ + + +V I + DVND+ P ++I ++T G + + A D D +L Y ++ N F+ ++ +G + + L Y ++V +D
Sbjct: 1 YSIMDGNDQGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFN--IRENTPA-AQVAIVTATDRDSGTNAAITYSLFSGEN----KFMMNSKTGEIRTVTP-LDHETKDSYTMRISAFDGKHTTF-VPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVG------------INARLSYSLVSG-DTSYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPS----RSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT--QVSATDRDSSTNGALVFGIIKGNDDGVF-TIDGSTGIISIAKSPDYENKTRYDLTVQARDRGV-PVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPEST--------------VIGSTVVTVTATDLDSGPRGRLEYRLISGNV--KGAFNIDANSGSIRVSSELDRETTPSYSLQVEARD 557 HSP 9 Score: 162.925 bits (411), Expect = 2.423e-40 Identity = 191/753 (25.37%), Postives = 329/753 (43.69%), Query Frame = 2
Query: 383 HGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQ------QRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNS-SLFSVLVKENTPARSMIFQLIANDPD---STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXX---XXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEF--SVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
+G + Y LS FSI+ + ++T+ +D E Q + + ++ V++ V DVNDN PQF+K V E + AG + TATD D + N +I Y + +++ +D+ R P LD E Y + I A + + V++ + D NDN P F S F++ E++P + + QL A D D + +V Y + F + ++ + S LD E Y + V +D +S+ V D ND +P+ ++ E+ E++ + QV V DKD+ +NG + SLS G+ T D + +KT D E ++ + + DG + S +++ + + I++ NDN P F + E+ I T ++K+NA D DG + S F+ID ++G+I+V +DRE +Y L + A ++GS + I V DVNDN+P + P + S+ ENL T+ ++ D D G NA V + + DT VN G + +PLDRE + + LRV D+G + + + + + D+NDN P+ + +++++ + G I +++A D D N ++TY I+ N F +STTG +++ + + Y + +S KDSG PP + + + ++
Sbjct: 614 NGDVRYALSDNTDVFSINTSTGLITLKTQLDYEKKT------------QYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGE-NLAAGVAVCYVTATDAD-SGANGKISYSILSGNENMAFAMDRFTGEITTRVP-------LDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTFTGPSRFNI--SEDSPTGTRVGQLTATDRDIGPNGAVT----YAIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEG-SNGA-----------ITLSLS-GEGSDNFTIDSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSK----SATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATD-SDGTPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAP-VFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSV--GDTSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHG-KPSQSAVAAITLTINDLNDNSPQFSQSK--------------YTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNH--GNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADE 1301 HSP 10 Score: 155.606 bits (392), Expect = 3.952e-38 Identity = 146/493 (29.61%), Postives = 229/493 (46.45%), Query Frame = 2
Query: 1121 GTVILISSWLDYERHQRYKVPVFVTDGL---YEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKD-DSQTNGKMICEHETTEPRLEFSLSSGKNKKIL---TYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLA-PATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMI--TVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFI 2563
G++ D E RY++ V D ++ R+V+ + V+DEND +P+ N V + EN+ V IVT D DS TN + +SL SG+NK ++ T +IRT T D E ++ + DG +T+ F + + D NDN P F S Y V E+ +G+++ ++ A DLD G+N ++ YSL D S F +DS GVI +G DRE K Y++ + A D GS + + I + DVNDN P + + SV E++A A + + D D G NAD+ +S T N + V G + +++ LD E + + L + + D G +S + I V D+NDN P + +P + +PA TQ+ A D D +TN L + I+ N +F+ + +TG +S+ K + Y + V +D G P D +FI
Sbjct: 19 GSITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQV---AIVTATDRDSGTNAA-----------ITYSLFSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDGKHTT--------FVPLITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTS-HLLINVNDINDNPP-VFSPSAYQSRVKENTPAG----------------TQVSATDRDSSTNGALVFGIIKGN--DDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFI 468 HSP 11 Score: 97.4413 bits (241), Expect = 2.649e-20 Identity = 123/475 (25.89%), Postives = 212/475 (44.63%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPN-CCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLY--EARSXXXXXXXXXXXXSPQLIQNPSVI-EVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLD 1699
++EN V T+A D +G N S+I SG + F I+ S V+ +D E Q LE+ ++ + A V I V+++ND P F++Q V E S + S + + +A+D D + Y + S + +DQ R + + LD E + Y I++R +A + N V + + D NDN P+F+SS +S + EN+ S F+L A D D + R Y + N+ F + + VI ++ LD E Y + + D +A S+ + + ++ LI + S+ V EN K + +++ +D D L FSL S ++K + T D I TK DRE+ + ++ + +D N S L+S + + ++D +DN P+F+ ++Y ++E+ P G I++V A D+D
Sbjct: 1421 VRENSAQSTSVLTVAADDSDVGANAVLRYSII---SGNDEKRFKINSTSGVIMTTTPLDFEE------------KSQYGLEVTA---TDSKYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKV-SASDRD---SFGSLSYSIVGGKDSDKFSIDQ-RSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARI-TYNLSRNDA---FMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTG------------LNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPS----LSSVADVIIDVIDEDDNCPRFQPTEYNVTISESLPRGASIVQVTARDID 1852 HSP 12 Score: 91.2781 bits (225), Expect = 2.084e-18 Identity = 77/273 (28.21%), Postives = 121/273 (44.32%), Query Frame = 2
Query: 1736 HDFSLFQIDSTTGVITVQG-PVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSP-------GYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
+D +F IDS+TG IT G DRE + Y+L + A D+ + + I V D NDN+P L + F++REN A + + D D G NA + +S + +M + G + PLD ETKD + +R+ D + ++ I V DVNDN P ++SVY++ G ++ QL AVD D N +L+Y ++ +T F+ +S G + Y + + +D GSP
Sbjct: 7 NDQGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQVAIVTATDRDSGTNAAITYSLFSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDG-----KHTTFVPLITVDDVNDNAPFF---------------------ALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDT---SYFTVDS-QGVIRTKGAFDRETKASYQVALRAQDGGSP 249
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Match: EDO40470 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S751]) HSP 1 Score: 202.216 bits (513), Expect = 2.053e-52 Identity = 205/722 (28.39%), Postives = 314/722 (43.49%), Query Frame = 2
Query: 422 CFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQR-YKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENL--APATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFIT 2566
FS+D S ++T+AK +D E+ N L+ G G + + V I+VLDVND P FSK + E S +A S I A D NA++ Y +++ + + ++ L+L +++D E + ++A + + NV + V D NDN P+FNSS V + E+TP + + D DS + R +N LF++ N + ++ +DY R Y +PV DG RS +L D SP V+E + I +V+ TD D + NG++ ++ +F L +G I K+ DRE + ++ +I D +SS + V + D NDN P F+Q+ Y V EN P+ T + V+A D D+G NG + Y + + F +D TG IT +DRE K Y I A D GS P + + V DVND SP + +V E+L + + + +D G N+D+ + + V G L + PLDRE RH L V D G N ++ + I V+DVNDN P IN + + + + I G V+ ++AVD D N K+ Y I+ NT F N TTG +S + L Y ++VS D G +K Y +T
Sbjct: 646 VFSVD-GSGLITLAKLLDRET-QDNYLLTVKAVDGGGQDSVNKAI-----------VNITVLDVNDEPPIFSKAEYNFTIQEHS-QALSVIGHVHAISRDKG-TNAEVVYSISKGNTDNIVLINSTGT--LYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPG--TLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGE-NGRISYAFDSKVDTSKFGLRNGGK-------IFIKSKLDREDIEEYNLKVIAID----HGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKAFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTV--------PEKLPI------GSVVAAVLAVDSDQGDNGKVRYKIVNGNT--DGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKK---QQKTSYQLVT 1317 HSP 2 Score: 174.096 bits (440), Expect = 9.832e-44 Identity = 209/764 (27.36%), Postives = 334/764 (43.72%), Query Frame = 2
Query: 275 IKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELN-VDLYVDDFNDNPPRF-NSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXS---PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL-EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP--FEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFS-KTWPNDDTVMITVNGTLYITKP-LDRETKDRHCLRVRLRDNGLN-GRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
++ + ++ENEP+ +G ++ G N G + Y+ F +D+++ +T ++ +D E+ + S ++ G + Q+ +VR DVND P+FSK + V+E GS + ATD D N+ I Y + K+F L Q L L++ LD E +++ + A + N+ + +++ V D NDN P F N + F V E P S++ ++A D D + Y+ N F + + VI LD+E RY + V TD G + ++ +++ D + P +NP + + EN + + D DDS N ++ ++ PR F ++S T I+T DRE+ S+ S+ + +D T + L ++ T+ + I D NDN PKF S+ +V E+ P + + A D D G G + Y + D F +D TGV+ + G +D E Y LHI A D GS PL +S L V +++P T F +V EN T + ++ D D G NA++ +S + D I + L +T LDRE KD + L V G++ R SS V I V+D NDN P+ I+P ++ + SP +I L D D NTK+ Y I+ NT F+ +TG LS L Y + V KD P
Sbjct: 1016 FQQASYAFFVKENEPVATYLGAVSASDSDEGSN----GHVTYRFDTQVAQFIVDKQTGKITTSQVLDREAKA--SYVFSIVATDGGSSPRV----DKTQVTVIVR------DVNDCSPKFSKNKYSVTVNE-DLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKAFSL---NQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKT-VPEKLPIGSVVAAVLAVDSDQGDNGKV-RYKIVNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHD-DDSGLNSRIWYTIDSQSPRAHFKINSE------TGLIQTTHPIDREEISEYSLKVRATDQAFTEQD-RLYNTATLKIIIQDLNDNAPKF-VSRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPL-TSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTVHA--TGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPE---------------NSPARLIYTLTVQDLDYGNNTKVLYSIMSGNT--DGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPP 1728 HSP 3 Score: 161.77 bits (408), Expect = 5.958e-40 Identity = 185/680 (27.21%), Postives = 284/680 (41.76%), Query Frame = 2
Query: 539 ELIVNLWSNVQ--------LLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTH-YLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLD-DGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVD-SGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAP--ATIGQLQYEDSDIGRNADVVFSKTWPN-DDTVMIT-VNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL-INPRGLREIDDATSPAASQSISISVYQSP--GYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKD 2515
E I +L+ VQ L V I+V+D+NDN PQF+ I + E + G + + D D + ++ + L + + LD L L +D N Y + ++A + + + ++L V D ND P F + ++ V E TP S I +++A D DS R + + K L+NG I I S LD E + Y + V D RS + +D +P Q V EN +G V +D D+ +NG + +T + +GK I T DRE + ++ +DG +S + T + V + D ND PKF +++Y V E+ P+G+ +L + A D D G N I Y + F ++ TGV+T+ P+DRE+ + LH+ A D G+ L + + I V DVNDN P + F P + + + DSD G N V + N D T I G + + LD E +R+ LRV D G ++ S V I V D NDN+P NP I +Y++ +T + A DDD N+++ Y I + P F NS TG + P+ I Y +KV D
Sbjct: 768 EKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDT-PIGHTFYTVSVFDAD-SGVLGRVSFSLLSNPGTL-FNLDSNTGA-LSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFG--LRNGGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEG-SNGHVTYRFDTQVAQFIVDKQTGK--------ITTSQVLDREAKASYVFSIVATDG-GSSPRVDKTQ---VTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKAFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNP-----------------IITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTI--DSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATD 1409 HSP 4 Score: 158.688 bits (400), Expect = 5.434e-39 Identity = 186/670 (27.76%), Postives = 294/670 (43.88%), Query Frame = 2
Query: 584 VRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN-DLDAENQTHYLIKIRAWNAQDNKQWNELN-VDLYVDDFNDNPPRFNSSLF---SVLVKENTPARSMIFQLIANDPDSTSVLRFDL-YQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPR-----LEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVR--ENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDDTVM-ITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVC-IRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLI 2536
+R+ I+V D NDN P+FS + E + G+ I +A+D DI NA+I+Y + E H Q + + N LD E + YLI ++A + + Q + V + V D NDN P + S S V EN + + ++ +D DS ++ + + F VL + ++I + LD E H + + D R+ + + D +P+ ++ V EN+ ++ V D+D + + TTE R SSG I T T DRE+ Q+ + ++ D + L+ + ++ V + D NDN P F QS Y A + EN P G+ ++++ A D D G N I YS+ + F +D G++T +D E++ Y + A D G N++V +++T D+NDN P + P +SV EN +I QL+ D D + A F N D V + +G + + K LDRET+D + L V+ D G G+ + + I V+DVND P A + +I + VI + A+ D TN ++ Y I NT I NS TG L L + H I + V KD G+PPL
Sbjct: 156 LRLSITVEDTNDNKPEFSNVSYSGTIPE-NIDVGTSILQVSASDKDIG-TNAEIQYSI-ETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGM--------ITTATDLDREQIPQVVLTVLVHD----RGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLT--DLNDNQP-VFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVDGSGLITLAKLLDRETQDNYLLTVKAVDGG--GQDSVNKAIVNITVLDVNDEPPIF--------------SKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNT--DNIVLINS-TGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLF 788 HSP 5 Score: 157.532 bits (397), Expect = 1.349e-38 Identity = 204/779 (26.19%), Postives = 330/779 (42.36%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLES-----ICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKA--GSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN-DLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNE-LRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARS---XXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS--LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRE-NLAPATIGQLQYEDSDIGRNADVVFSKTWPN-DDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNG---LNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSH-HYIGHYPIKVSVKDSGSPPLIDEKMFYLFITN 2569
I EN + + ++ + +G N E S I S P F I + V+ +D E+ I + E G H QL + VRI VLDVNDN P + + A G+ + + +D D + +N ++ L F + D + + LD E H+ +K + D + E + + V D ND P+F+ + V EN +++ + A D D S S L + + T + F++ + +I ++ LD E+ + + V V D S + V + D ND P Q+ + ENS G + Q++ D D + + + + P F L +K L + RT D E S + + +DG S N T++V + D NDN P F S Y EN IG I ++ A D D + +E + +F +D +G+IT+ +DRE +++Y L + AVD G + +NITV DVND P + F+++E + A + IG + D G NA+VV+S + N D+ V+I GTLY+ +D E L V+ +D G L G V I VID+NDN P+ + L + + T P ++SV+ D D ++++ +L + P +F+ +S TG LSL K + + + Y + V +D GSPP M L + +
Sbjct: 181 IPENIDVGTSILQVSASDKDIGTNAEIQYS-IETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAE-----DKGSSH-----------QLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDAD-SGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENS---LILYSILTPNTPFFLDP---RKGLVTNSRT---LDHEVQSSYTFQVAATDGGGRSCNA------TVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVDG-SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGY----ANVTIAVIDINDNSPQFNSSSILVRLPEDT-PIGHTFYTVSVF-------------DADSGVLGRVSFSLL---SNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVD 904 HSP 6 Score: 156.377 bits (394), Expect = 2.404e-38 Identity = 198/720 (27.50%), Postives = 310/720 (43.06%), Query Frame = 2
Query: 293 KYLIQENEPIDRMVGT-----IATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELN-VDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEAR------SXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEP---RLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL--FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLN-SSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMIT--VNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHI 2389
KY + NE D VG+ IATD + G N + ++ +GP FS++Q + VLT+ +D E +R + +S +G N L + + I+VLDVNDN P F + + V E GS + A D+D +N ++ Y + + +++ + L LD E Y++++ A + +Q V +YV+D NDN P F+ + + EN P + + + A+D DS R Y + R F + +I + +D E Y + V TD + + + L+++++D ND +P+ + ++ VME+ + + D D Q E+ P + L +G K I + D E Q ++ + +D + LTS NV ++D NDNPP+F + + V+EN P GT ++KV AYD D G N ++ YS+ + F ID +G+I +DRE K+ Y L +HA S P SS + I V D NDN P ++P V EN I L +D D G N V++S N D G L T LDRETK + L V+ +D + + I + D NDN P + S +IS PG I L A D D +N + Y +
Sbjct: 1123 KYSVTVNE--DLPVGSSLLTLIATDDDQQGPNSDITYMIV---AGPKA-FSLNQVTGVLTLVSPLDRE--VTHRHILHVVASDKG---------GNQSLETITYIEINVLDVNDNYPVFINETTFKTVPE-KLPIGSVVAAVLAVDSDQG-DNGKVRYKIVNGNTDGTFKINETTG-VISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRI-WYTIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSR-NLTYVMEDEPFNFQVTSITALDPDTGQGGN---VEYRIVSPDTGKFSLDLKTGVLKLI--------GSLDYEDVPQYTLHISATD----LGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTVHATGV-SYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENSPARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDI-TPPYYTAFANITIFIEDQNDNPPVF--------------QQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTL 1789 HSP 7 Score: 131.339 bits (329), Expect = 1.153e-30 Identity = 168/673 (24.96%), Postives = 277/673 (41.16%), Query Frame = 2
Query: 590 VRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDL---------DAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVI----------EVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHD------FSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSP--GYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSG 2521
V + V D+NDN P F + + V + K + A D+D + Q Y + + L +R L DL D E Y++ I A + + L + + V+D NDN P F++ +S + EN + I Q+ A+D D + +++ + +F + VI+ + LDYE + Y + V D + S E + N VI +V EN+ G + +V V+D DS NG++ E + ++ I I + DRE + +C D + SF INV D ND PKF + Y V EN + T++ VNA D D G N ++ Y++ + F ID ++G+IT +DRE L + D GS PL+ + + + + D NDN P + + S+ EN + + QL +D DIG N+ +++S PN + G + ++ LD E + + +V D G R + V + + D+NDN+P + +P S S+ +++ G I QL A+D D + I N ++FS + +G ++L K L +Y + V D G
Sbjct: 44 VLVYVQDLNDNSPSFVRGTSAKLVVFENDKDFRQKLI--AVDSDFGSNSTQ-SYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAED---KGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDA-DSGKNGEVNVTLEGGDGYFSMKFDVLNDESI----IAVGQSLDRETHDHFFLKAVCIDKGDPPRTTE--KSFRINVG--DVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATD---GGGRSCNATVHVSLTDLNDNQP-VFDP---------------SSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNA--DEVFSVDG-SGLITLAKLLDRETQDNYLLTVKAVDGG 679 HSP 8 Score: 124.02 bits (310), Expect = 2.197e-28 Identity = 176/727 (24.21%), Postives = 300/727 (41.27%), Query Frame = 2
Query: 509 SDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLL-----NDLDAENQTHYLIKIRAWNAQDNKQWNELN----VDLYVDDFNDNPPRFNSSLFSVLVKENTPA--RSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSX--XXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDI-----------RTKTAFDREKSSQISVVLICSDG---WNTSANIHLTSSFT-INVQILDFNDNP--------------PKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLN-GKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPATI-GQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKP--RLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVK--DSGSPPL 2533
S+ G+ L +I + L V+I + ++ D+ P+F Q R + K GS+I A A +AQ+ Y + +K +D P+ ++ + LD E+ ++ + + A + W LN +D+ V D NDN P F+ S + E+T A + ++ A D DS + + NE +F++ I + LD E + + + TD +S +V + +++P L S + + E++ G V+ V+ TD D E RL ++L S I + + K +F S QI + G + ++ + SF I VQ +D P PKF YF V EN +GT +L V D GL G+I Y++E+ + F+I +GVI+V P+D E K + L + A+D + V + I V DVND P + + E + TI + D D G N V F+ DD ++ G + + LD ET H + VR D G + + V IRV+D+NDN P R+ P ++ +++ P S+ + ++ A D D N +L++ ++ +F + +G+L+ + + Y +++K D+G+PPL
Sbjct: 1921 SNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR----ASSDAQVTYSIISGNKGRAFYVD----PFTGVISVASADALDYESTKNFRLHLVATP----QGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEA-GVFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIREDTRTGAVVTSVVATDTD--------------KESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIITREPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENS-NYFRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFA-IQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEG-SPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENL--PLNSR-------------LYEINATDRDSGANARLSFTVI--GGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPL 2600 HSP 9 Score: 115.931 bits (289), Expect = 6.365e-26 Identity = 184/778 (23.65%), Postives = 317/778 (40.75%), Query Frame = 2
Query: 383 HGSLIYKLSGPN-CCFSIDQKSSVLTIAKNIDLESICINRELSSDC-SSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDI-APENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRF-NSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISS--WLDYERHQRYKVPVFVTDGLYEARSXXX---XXXXXXXXXSPQLIQNPSVIEVMENSG--KGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKF---------------------------RQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTGVITVQGPVDRELKEHY-KLHIHAVDSGSIPLNSSVGLNITV------------DDVNDNSPCLLTPFEFSVRENLAPATIGQLQY--EDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
+G+++Y LS +SID ++ ++ A + I +E + C + QG +A+V VRI + D N++ PQF+K E H+ + A + + + TATD D N ++ Y L + S L + + + Q + + I A + V + + + D+PPRF N + V + EN+ S I + A V Y + + F V VI ++S LDYE + +++ + T + + + + V D ND SP + + ++ E++G K + +V TD DS TNGK + +S+ +G + T D I T DRE ++ +V+ +D S +++ + V + D NDNPP F ++S+ ++ G IL+V+A D D G N +I YS D ++ID+ TGVI+ + +D +++ + ++ + A+D G P + V + I + V +N+ + V +N A +G++ Y E+S+ R + +G + + KPLD ETK R L V D+ + V I V DVND KP + + A S I V G ++ + A D D N ++ + I + S F+ + TG + + L H I + + V D GSPP+
Sbjct: 1782 NGNIVYTLSNDTYGVYSIDSRTGIVYSAARFE---TSIKQEYNFFCIAKDQGQDPK----------MAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNT-SASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSDAQV----TYSIISGNKGRAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDV-DSGTNGK-----------VTYSIWTGNEAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTD----SGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIITREPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSNYFR----------------IGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRV-PVYINVSDVNDEKP----------VFGQSGYMAQWSEGIPV----GTIVVNVSAADKDSGANGRVWFAIQSGDDKGS--FAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPM 2492 HSP 10 Score: 110.923 bits (276), Expect = 2.436e-24 Identity = 141/595 (23.70%), Postives = 247/595 (41.51%), Query Frame = 2
Query: 578 AVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS----TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GLYEARSXXXXXXXXXXXXS--PQLI-QNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-------IRTKTAFDREKSSQISVVLICS-DGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAEN-GPIGT-VILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRE------------------------NLAPAT-----IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHC-LRVRLRDNGLNGRRQSSGEVCIRVI 2203
A + I + D NDN P F + +SE + G+ I TA+D D + N I Y L+ + ++ + R ++ + + Y A + + + + V + ++D N++ P+F + + V + NT A +++ + A D D+ + + L + N+ LF V N + S+ R+ + + D G R V + N + P+ + Q P+ + + ENS G I V D+Q + +S+ SG + D + + A D E + + L+ + GW + L +++ ++D NDN P F S A +AE+ G ++KV A D+D G NGK+ YS+ ++ +F IDSTTG IT +DRE + L I DSG P +++ + + V D+NDN P E ++RE NL A+ I ++ D D G NA + +S N D + ++ G + + +D +D + V+ D G+ +R V +R+I
Sbjct: 1732 AFANITIFIEDQNDNPPVFQQSLYSSTISELT-PPGTSILNLTASDKD-SGSNGNIVYTLS--NDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNST--SLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSDAQ---------------VTYSIISGNKGRAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGW-----VSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQR---ALVYVRII 2297 HSP 11 Score: 83.5741 bits (205), Expect = 4.881e-16 Identity = 104/385 (27.01%), Postives = 163/385 (42.34%), Query Frame = 2
Query: 1457 IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKF-RQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHD-----FSLFQIDSTTG------VITVQG-PVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYL 2557
I TKT DREK S ++ ++ ++T S+T+ V + D NDN P F R + V EN K+ A D D G N Y++ F L T G V+ VDRE + Y L+I A D G+ + + L+ITV+D NDN P + ++ EN+ T I Q+ D DIG NA++ +S +D + ++ G + LD E K + + V+ D G + + SS V I V+DVNDN P + S S ++ + G + ++ D D N ++ + + S F + +++ + L H+ +K D G PP EK F +
Sbjct: 14 ITTKTVLDREKVSAYNLTIVE---FSTPPK-----SYTVLVYVQDLNDNSPSFVRGTSAKLVVFENDK--DFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVI-----------HVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRI 377 HSP 12 Score: 68.5514 bits (166), Expect = 1.649e-11 Identity = 87/378 (23.02%), Postives = 164/378 (43.39%), Query Frame = 2
Query: 683 GSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD----GLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSS--QISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-LFQIDSTTGVI 1780
G+ + TD +I Y + E+ F++ QR + + LD E + +L+ + A + + + V + V D ND P F S + E P +++ + A D DS + R + + + + F++ + VI LD+E + + V V TD ++ SV +++ ++ + P+ ++V+EN + ++ TD+D S N RL F++ G + + D + T FD E ++ Q S+ + +D + N L+S+ TI V + D ++ P F + Y V N IG + +V A D D G G++ + + S ++++TTG+I
Sbjct: 2320 GTSVLTVRVTDNAAGLPLGRISYNI-ENSNYFRIG---QRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRV-WFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLYEINATDRD-SGANA-----------RLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATD----AGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGRVFFVFYNPTSNALKMNATTGII 2676 HSP 13 Score: 55.0694 bits (131), Expect = 2.341e-7 Identity = 79/265 (29.81%), Postives = 107/265 (40.38%), Query Frame = 2
Query: 1772 GVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL--TPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITV-----NGTLYI-------TKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGS 2524
GVIT + +DRE Y L I S P S L + V D+NDNSP + T + V EN +L DSD G N+ ++ N V + +G LY + +DRE D + L + D G N + I V D NDNKP N S S +I G I Q+ A D D TN ++ Y I ++ P IF + TTG + + L + Y I V +D GS
Sbjct: 12 GVITTKTVLDREKVSAYNLTIVEF---STPPKSYTVL-VYVQDLNDNSPSFVRGTSAKLVVFENDKDFR-QKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGG-NPANHGFLRLSITVEDTNDNKPEFSN--------------VSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIET-HSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGS 255
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Match: EDO33359 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSF2]) HSP 1 Score: 187.193 bits (474), Expect = 8.397e-49 Identity = 205/760 (26.97%), Postives = 327/760 (43.03%), Query Frame = 2
Query: 302 IQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPN--CCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL--AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDD---GLNGKIHYSLEHDF--SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYIT--KPLDRETKDRHCLRVRLRDNG---LNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
+ EN P+ GTI ++ + + + LIY + N F+ID + + K D E S +G V S++ VV I V+D NDN P+F+++R V E + G+ + TA D D P NA ++Y + +F + D L+ EN T LI + + + V++ V N++ PRF + ++ + EN P + I ++ A + D + RF +Y + K+F V Q G + L + LDYE +RY+ E+ EN G + + D+D+ NG++ T+ + F+ +S LT ++ DRE Q +++++ DG + T+S + V++LD NDNPP F Y ++E IGT IL+V+A D DD G+N +I Y L+ F I+ TTG IT++ VD E + Y + A D G L S + IT+ DVNDN P L T + + EN+A T + Q+ D D N V+FS N D + T +T K LD E + L ++ D G LN + G + + V+++NDN P ID+ T + G+VI ++ A D D + N K+ + IL N+ F + TG ++ +K L + + Y + + D G PPL
Sbjct: 118 VSENTPL----GTIVARVKAVDKDSTSNADLIYSIQNGNNNGSFTIDNSTGEIMTRKEFDFEKTERYNLTISVSDTG-------VPALSSLNFANVV---IIVVDENDNPPEFAQKRYTATVYE-NFTVGTVVLRVTAHDKDSGP-NAMLKYSIHSGNTDDAFVIIADSGDISLDKPLDKETIENYTLVLI-VTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARF-IYVIKDAASSKVFLVNQTGDITL-ARELDYETRRRYE------------------------------------FEMYENVTSGTQVLTLFAHDRDEG-INGQVFYYIVTSSVKGVFTTNSTTGVVSLTAEL------DRESVYQYNMLVVAQDGGSPPR----TASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSANDRDDKDEGVNAEIRYFLKDAIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKVLFSILGGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQ--PGMLHVSVVNINDNSPVFSQKMYSASIDENT--------------TVGHVILRVTASDLDSSLNGKVLFSILEGNS--DGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPL 793 HSP 2 Score: 134.035 bits (336), Expect = 5.903e-32 Identity = 120/390 (30.77%), Postives = 184/390 (47.18%), Query Frame = 2
Query: 818 LLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELR---------KLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEAR----SXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS--LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVG--LNITVDDVNDNSPC 1921
L +LD E+ Y + + A + + +V + V D NDNPP F + +++ + E T + I ++ AND D D + N E+R K FS+ I I +DYE Y VF +DG EAR S + + + D ND P + ++++EN G + QV +D DS NGK++ FS+ G + D + T + D E ++ ++V+ +D + N + ++V +++ NDN P F Q Y A + EN +G VIL+V A DLD LNGK+ +S+ S F +D TGV+T +D E Y L I A D G PLNSS L+++V ++NDNSP
Sbjct: 447 LTAELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSANDRD-------DKDEGVNAEIRYFLKDAIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDG-GEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDL-DSSLNGKVL-----------FSILGGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLN--SSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNGKVLFSILEGNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPV 814 HSP 3 Score: 133.265 bits (334), Expect = 1.203e-31 Identity = 152/610 (24.92%), Postives = 256/610 (41.97%), Query Frame = 2
Query: 950 PRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGT-VILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSP-QLIQNPSVIE--VMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSD-GWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS--LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNS--SVGLNITVDDVNDNSPCLLTPF-EFSVRENLAPAT-IGQLQYEDSDIGRNADVVFS-KTWPNDDTVMITVNGTLYITKPLDRETKDRH---------------CLRVRLRDNGLNGR--------------------------------------------------RQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
P FN +L+S ++ E+ + ++A D D+ R Y + + V+ N T V+ S DYE + Y V D RS + + D + + I P E V EN+ G ++ +V DKD S +N +I +S+ +G N T D I T+ FD EK+ + ++ + SD G ++++ + I ++D NDNPP+F Q +Y A V EN +GTV+L+V A+D D G N + YS+ + F I + +G I++ P+D+E E+Y L + D G PL S + +N+ V VN+++P L F S+ ENL T I +++ + D+ A ++ K + ++ G + + + LD ET+ R+ L RD G+NG+ R +S V + V+D NDN P ++ +ATS ++ + +S D D+ N ++ Y L + + S+ FS N TTG +++ + + + Y +V D G L
Sbjct: 1 PIFNQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARV-TYSIVSFSTESDYFVIDNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKD-STSNADLI-----------YSIQNGNNNGSFTIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPALSSLNFANVVII---VVDENDNPPEFAQKRYTATVYENFTVGTVVLRVTAHDKDSGPNAMLKYSIHSGNTDDAFVIIADSGDISLDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIKDAASSKVFLVNQTGDITLARELDYETRRRYEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATS-IGTRILRVSANDRD----------DKDEGVNAEIRY--FLKDAIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGEARL 581 HSP 4 Score: 121.324 bits (303), Expect = 7.004e-28 Identity = 125/435 (28.74%), Postives = 192/435 (44.14%), Query Frame = 2
Query: 989 ENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSV-------IEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKIL-----TYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS--LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVG--LNITVDDVNDNSPCLLTP-FEFSVRENLAPA-TIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYIT--KPLDRETKDRHCLRVRLRDNG---LNGRRQSSGEVCIRVIDVNDNKP 2224
EN + + + L A+D D + Y + ++ +F+ V+ +++ LD E +Y + V DG R+ + + D + NP V +++ E + G I +V D+DD + E + + L K T I K A D E+ S S + SDG LT S ++ + I+D NDN P F ++Y+ + EN IGT + +V A DLD LNGK+ +S+ S F ID TGV+T +D E Y L I A D G PLNSS L+++V ++NDNSP + S+ EN I ++ D D N V+FS N D + T +T K LD E + L ++ D G LN + G + + V+++NDN P
Sbjct: 399 ENVTSGTQVLTLFAHDRDE-GINGQVFYYIVTSSVKGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCN----DNPPVFTTLYYTLQLSEATSIGTRILRVSANDRDD---------KDEGVNAEIRYFLKDAIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGEA----RLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKVLFSILGGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNGKVLFSILEGNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQ--PGMLHVSVVNINDNSP 813 HSP 5 Score: 69.3218 bits (168), Expect = 7.042e-12 Identity = 104/429 (24.24%), Postives = 186/429 (43.36%), Query Frame = 2
Query: 365 GINLEFHGSLIYKL--SGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPE--NAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD----GLYEAR-SXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPP 1609
GIN G + Y + S F+ + + V+++ +D ES+ Q ++ ++ + A V++ VLD NDN P F+ +SEA+ G+ I +A D D E NA+I Y L + S + ++ + + +D E ++ Y ++ A + + + +V + + D NDN P F + + V + EN + + Q+ A+D DS+ + L+ F + QN V+ + LDYE Y + + TD L ++ +L V V + ND SP Q + EN+ G VI +V +D DS NGK++ FS+ G + D + T + D E ++ ++V+ +D + N + ++V +++ NDN P
Sbjct: 418 GIN----GQVFYYIVTSSVKGVFTTNSTTGVVSLTAELDRESVY------------QYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEAT-SIGTRILRVSANDRDDKDEGVNAEIRYFLKDAIVSKKFSINDTTGQ-ITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGKV-LFSILGGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDL-DSSLNGKVL-----------FSILEGNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLN--SSQPGMLHVSVVNINDNSP 813 HSP 6 Score: 56.6102 bits (135), Expect = 5.539e-8 Identity = 51/211 (24.17%), Postives = 91/211 (43.13%), Query Frame = 2
Query: 578 AVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHY--LIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD 1198
A+ + + + D NDN P F E VSE + G+ + A D D + NA + Y + + + +D + + D E Y I + N NV + V D NDNPP F ++ V EN +++ ++ A+D DS ++L++ ++ ++ F ++ + I + LD E + Y + + VTD
Sbjct: 91 AIATIHVQITDTNDNRPIFQPMEYETRVSENT-PLGTIVARVKAVDKD-STSNADLIYSIQNGNNNGSFTIDNSTGE-IMTRKEFDFEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGTVVLRVTAHDKDSGPNAMLKYSIHSGNTDD---AFVIIADSGDISLDKPLDKETIENYTLVLIVTD 295
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Match: EDO34815 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN97]) HSP 1 Score: 187.193 bits (474), Expect = 1.003e-48 Identity = 193/665 (29.02%), Postives = 306/665 (46.02%), Query Frame = 2
Query: 302 IQENE----PIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCC-FSIDQKSSVLTI----AKNIDLESIC-INRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL-AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGL-YEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFT----INVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPAT--IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKP---LDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKP 2224
IQEN P+ +ATD + +E + + Y+L+G + F+++ ++ V+T ++D E + + +G GH L V I VLD NDN P+F I+ +SEA+ G + TA D D + N +I + + + F++ + + + LD E + Y++ + A + + + V + + D NDN P+F F+V V E S+I A DPD S + + + + F++ N + I+ LD E Q Y V DG E+ + V + DEND SPQ +V++ + G ++ V D+D NG + L F + T +I T + DRE+ S ++V N S H + FT +N+ + DFNDN P+F QS+Y A V EN P+GT + V A D D G+N +I YSL +F I+ +TG I +Q ++RE KE+Y + I A D G+ L+S +++ V DVNDN P + +E ++ E A A + Q+ D+D+ RN V + T + M T+N T + + L+RE+KD + L V RD G G + + VID NDN P
Sbjct: 232 IQENSGPGVPVQMASSIMATDRD-----IESNADVRYRLNGSDSIQFAVNPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESL-------------AEVVIHVLDANDNTPRFIPSSIQSTISEAA-SIGQSVARVTANDPD-SGLNGRIFFSINSGSEGKFEIG---RSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSMSYPG-------FAINSNTGSVTITRPLDRETKQAYSFTVHARDGGGLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGN-NGHVTYAILI----LPFIIVPD------TGNINTSSKLDREQQSLYTLVHYV---LNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMYSLTGGDGVFSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHVLDVNDNPPVFTSRVYERTMSEGNAAAGEFVVQVNATDADVERNGHVTY--TIMHGALGMFTINETTGVIRTQGVLNRESKDFYTLIVMARDQGAV-PYMDFGTIDVHVIDKNDNTP 849 HSP 2 Score: 177.563 bits (449), Expect = 1.394e-45 Identity = 186/673 (27.64%), Postives = 294/673 (43.68%), Query Frame = 2
Query: 575 LAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLET---ATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN---DLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEAR---SXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIV--TDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKE-----HYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLID 2539
+A+ VRI LD NDN+P+FS R + E S G + + + ATD DI NA + Y L S Q ++ + ++ LD E T+Y + A + + V ++V D NDN PRF S + E + ++ ANDPDS L ++ + N+ F + ++ V+ +S LD E Y + V DG Y R + V ++D ND +P+ + ++V E G+ +G VIV T D Q + I + + P + ++G + DRE S + DG +N+ +NV+I D NDN P+F QY V + P+GT++L VNA D D G NG + Y++ F I TG I +DRE + HY L++ D G S LNI+V D NDN P + + +V EN+ T + + D D G N+ +++S T + + G + + K ++RE K+ + + + D G S +V + V+DVNDN P + R + + + A G + Q+ A D D N +TY I+ +F+ N TTG + L+ Y + V +D G+ P +D
Sbjct: 206 IAIALVRI--LDRNDNVPKFSHARYTGSIQENS-GPGVPVQMASSIMATDRDIE-SNADVRYRL-NGSDSIQFAVNPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSG--LNGRIFFSINSGSEGKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSE----GVAVGSVIVNATATDPDQGSNAAIT-YSMSYPGFAINSNTGS--------VTITRPLDRETKQAYSFTVHARDGGGLESNV------AVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIL--ILPFIIVPDTGNINTSSKLDREQQSLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMYSLTGGDGVFSIEPSTGQIRLQKAINREAKENYHVTITASDRGTP-VLSSDAKVHVHVLDVNDNPPVFTSRVYERTMSEGNAAA-------------GEFVVQVNATDADVERNGHVTYTIMHGAL---GMFTINETTGVIRTQGVLNRESKDFYTLIVMARDQGAVPYMD 833 HSP 3 Score: 163.31 bits (412), Expect = 4.479e-41 Identity = 172/652 (26.38%), Postives = 292/652 (44.79%), Query Frame = 2
Query: 626 PQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHH-----KSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLY----EARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVI---GQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF-SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN-GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHIL-LPNTLPSQIFSFNSTTGYLSLDKPLSHHY-IGHYPIKVSVKDSG 2521
P F+ +E S G I ATD+D N ++Y + + + + LD + +L+ + Y + I A + V + V D NDN P FN + +S V EN+P + + + A D DS + + + + ++ L + + + N I ++ LD E + Y + + TDG A ++ V + D ND P+ + ENSG G+ + ++ TD+ D ++N + ++ ++F+++ ++T + + D E+++ + +I +D T S + + +LD NDN P+F S + ++E IG + +V A D D GLNG+I +S+ F+I + GV+ V G +DRE K Y L++ A+D P + +T+ DVNDN+P P F V E +A + I D D G NA + +S ++P I N G++ IT+PLDRETK + V RD G +S+ V + + D NDN P+ + ++ D T P G ++ + A D D N +TY IL LP + + N+++ LD+ Y + HY + +SV D G
Sbjct: 1 PVFTPASYNATFTEGSSTRGVLIATVKATDSDDG-ANGDVDYSIVDGNVGDPRSNSDFTLDPNTG-MIKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVPKFSHARYTGSIQENSGPGVPVQMASSIMATDR-DIESNADVRYRLNGSD-SIQFAVN--PRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHE----SLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSGSEGKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSMSYPG---FAINSNTGSVTITRPLDRETKQAYSFTVHARD---GGGLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRT-PV-------------GTIVLAVNAEDRDVGNNGHVTYAILILPFIIVPDTGNINTSS---KLDREQQSLYTLVHYVLNLSVTDHG 619 HSP 4 Score: 162.54 bits (410), Expect = 7.073e-41 Identity = 191/743 (25.71%), Postives = 327/743 (44.01%), Query Frame = 2
Query: 416 NCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGL--AEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLY-VDDFNDNPPRFNSSLFSVLVKENT----PARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILIS----SWLDYERHQRYKVPVFVTDGL---YEARSXXXXXXXXXXXXSPQLIQNPSVIE--VMENSGKGLVIGQVIVTDKDDSQTNGKMICE-HETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLT-PFEFSVRENLAPATIG-QLQYEDSDIGRNADVVFS-KTWPNDDTVMITVNGTLYITKPLDRETKD-----RHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFI 2563
N F++D + ++ A+N++ + + S + + G L A RV I V D+NDN P F+ V E S G+ + TATD D + +NA + Y + + H F+ + + +LD E Y + I A + + + L + D NDN P+F+ + ++ ++EN+ P + M ++A D D S + +R+ L N F+V VI LD+ER Y V D +E+ + + + V D ND +P+ I PS I+ + E + G + +V D D S NG++ + +E + E S G +R + DRE + + + DG + + T+ V + D NDN PKF + + V+E +G+VI+ A D D G N I YS+ + F I+S TG +T+ P+DRE K+ Y +HA D G L S+V +N+ + D NDNSP T ++ V + TI + ED D+G N V ++ P +++ G + + LDRE + + L + + D+G+ + S + I V D NDN+P+ + S ++ G +T + A D+D N+++ Y + T +FS +TG + L K ++ +Y + ++ D G+P L + ++ +
Sbjct: 54 NSDFTLDPNTGMIKTARNLERQ-----QTFSYNLTIGAADHGL-------PSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENS-PVGTSLLDVTATDAD-SGQNAYVTYSVTAGDSHGLFRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVPKFSHARYTGSIQENSGPGVPVQ-MASSIMATDRDIESNADVRYRL----NGSDSIQFAVNPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFI--PSSIQSTISEAASIGQSVARVTANDPD-SGLNGRIFFSINSGSEGKFEIGRSDGV--------VRVSGSLDREAKAVYVLNVSAIDGSYSPREGY----GTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSMS--YPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDGGG--LESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAILILP---FIIVPDTGNINTSSKLDREQQSLYTLVHYVLNLSVTDHGVT-QFTSFALLNISVTDFNDNQPQF--------------NQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMYSL----TGGDGVFSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHV 736 HSP 5 Score: 110.153 bits (274), Expect = 2.067e-24 Identity = 119/432 (27.55%), Postives = 184/432 (42.59%), Query Frame = 2
Query: 1304 SGKGLVIGQVIVTDKDDSQTNGKM---ICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHD-----FSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNS---SVGLNITVDDVNDNSPCLL-TPFEFSVRENLAPATIGQLQYE----DSDIGRNADVVFSKTWPNDDTVMITVNG-----TLYITKP--LDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPP 2530
S +G++I V TD DD NG + I + +PR + N + I+T +R+++ ++ + +D S +++ +++ + D NDN P F + Y V EN P+GT +L V A D D G N + YS+ F S G I V G +DRE+ + Y L I A D G +P++ ++ L + + D NDN P + S++EN P Q+ D DI NADV + D++ VN T ++ P LD E + V D G +S EV I V+D NDN PR I P++ QS +IS S G + ++ A D D N ++ + I N+ F + G + + L Y + VS D P
Sbjct: 17 STRGVLIATVKATDSDDG-ANGDVDYSIVDGNVGDPRSNSDFTLDPNTGM----IKTARNLERQQTFSYNLTIGAADHGLPS----FSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATD-GGVPISRTAIAIAL-VRILDRNDNVPKFSHARYTGSIQENSGPGVPVQMASSIMATDRDIESNADVRYR--LNGSDSIQFAVNPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTG-HESLAEVVIHVLDANDNTPRFI-------------PSSIQS-TISEAASIGQSVARVTANDPDSGLNGRIFFSI---NSGSEGKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSP 417
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 187.578 bits (475), Expect = 6.577e-48 Identity = 210/782 (26.85%), Postives = 334/782 (42.71%), Query Frame = 2
Query: 317 PIDRMVGTIATDIEGLGINLEFHGSLIYKL---SGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLI---KIRAWN----AQDNKQ---WNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDR--EKSSQISVVLICSDGWNT---------SANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEK-MFYL 2557
P D+ +G + + +G + Y + G N FSI + S +T+ K +D E + L++ N A V V+I++LDVND PQFSK+ + E + ATD D N ++ + + + F +N ++ E + + I +N AQD Q +N+ VD+ + D NDN P+F SS F ++ EN +++ A D D + + F Q N+L FS+ +N I I LD E+ ++ + D E + + + + D ND P+ Q + ENS G + QV D D TN + Y I + + DR + Q + L C+ +NT +++ L+S+ + V + D N + P+F++ Y A V E+ +GT +L V A D D G N KI YS+ F +D TTGVI G +DRE + Y+ + A D G L + + I + DVNDN P L P +E VRE++ P + ++ D+DIG+NA +++S D T++ G + KPLDRET + L V D G Q+S +V + + DV D+ P P + + T P +SP VIT + A D + T + Y I+ N+ Q+F N TG + L + Y +++V+ + SP + M YL
Sbjct: 138 PEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKV------------PTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIRE-DVPVNQLVTTVRATDCDQG-SNGEVFFEIVSGNDM-----------NFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQ---NDLP--FSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTN--------------------------VVYSIVSSSGHDRCFRINPQGLITLSCTLNYNTKHVYVFSVSASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQG-TPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPP-----------RSP--VIT-VKAKSQDLSPETGMMYSIVRGNS--PQVFDINPNTGAIQTLMKLDYETQSEY--RLTVRATLSPFFTETTVMVYL 844 HSP 2 Score: 150.984 bits (380), Expect = 1.326e-36 Identity = 186/759 (24.51%), Postives = 316/759 (41.63%), Query Frame = 2
Query: 302 IQENEPI--DRMVGTIATDIEGLGINLEFHGSLIYKLSGPN-----CCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG----LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHY---SLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPP 2530
+QE+ + D VGT+ + + +G + Y +S FSIDQ + V+T + +D E + + G+ LE ++L I+VLDVNDN P F + + E G + A+D D + N +++Y + + + ++ LD E Y ++++A + + + + V + + D ND P+F+ ++S ++E+ P ++ + A D D S + N++ FS+ + + + LDYE + + V D LY ++ +++ + D ND +PQ + + + EN G +V DKD TNG++ + L FS++ T I K DREK + + + D + I + +LD NDNPPKF Q +Y +AEN GT +L+V A D D G ++ S HD F+I+ G+IT+ ++ K Y + A D L+S+ + + V D N ++P + V+E+ + T + + D D G NA + +S + + G + LDRE D + V D+G+ + S V I + DVNDN P + P S + PG + ++ A D D N ++ Y N F+ +ST G + KPL I Y + V D G+PP
Sbjct: 23 LQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDL------------TINVLDVNDNGPIFERNIYAADIPE-DKSIGDFVLAVRASDAD-SGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDM-NFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYN-QTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHG-TNGEITFSFMQND--LPFSINEN------TGGISIKEELDREKVPKFTFGIKARD----KGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHD-RCFRINPQ-GLITLSCTLNYNTKHVYVFSVSASDGM---LSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSF-VYIHIADVNDNDPVFLKP--------------SYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYS-FASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPP 731 HSP 3 Score: 129.798 bits (325), Expect = 3.342e-30 Identity = 124/438 (28.31%), Postives = 193/438 (44.06%), Query Frame = 2
Query: 1259 PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTY--------DIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL---EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENL-APATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMIT--VNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
PQ + V E++ G V+ V +D D S +NG + +S+S +N TY I TK DRE + + DG S ++ TINV LD NDN P F ++ Y A + E+ IG +L V A D D G NG++ Y + + D S F I +G +TV +DRE Y L + A D G+ P +++V + IT+ DVND +P + ++RE++ + ++ D D G N +V F ND +NG + + + LD E L V +D G + V I +IDVNDN P+ ++ I + + ++ Y+ Y D D TN ++T+ + N LP FS N TG +S+ + L + + + +D G P
Sbjct: 18 PQFSRLQEDASVSEDAEVGTVVATVSASDPD-SGSNGM-----------IRYSMSPSQNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYM--DLTINV--LDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKG-QPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPE------NYAVGQEFYRVQAY--------DKDHGTNGEITFS-FMQNDLP---FSINENTGGISIKEELDREKVPKFTFGIKARDKGVP 420 HSP 4 Score: 122.865 bits (307), Expect = 4.427e-28 Identity = 120/444 (27.03%), Postives = 208/444 (46.85%), Query Frame = 2
Query: 941 DNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTS--VLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKM-ICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTP-FEFSVRENLAPATIGQ----LQYEDSDIGRNADVVFSKTWPNDDTVMITVN-GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL 2230
+NPP+F+ V E+ +++ + A+DPDS S ++R+ + + N FS+ Q VI LD E R+ V DG E L + V D ND P +N ++ E+ G + V +D DS +NG++ C + FS+ ++ + DREK ++ + D N +++ T+ + +LD ND P+F + Y A + E+ P+ ++ V A D D G NG++ + + +D + F I+ G + V+ +D E+ + L + A D G L + ++I + DVNDN+P ++ F+ + EN A +GQ +Q D D G N ++ FS ND I N G + I + LDRE + ++ RD G+ ++ + ++ I ++D+NDN P+
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDA-DSGSNGEVKYCILNSDGDNSAFSIGE------VSGAVTVMKKLDREKVPTYTLQVQAQD----QGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYA---VGQEFYRVQAYDKDHGTNGEITFS-FMQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVP-FKEGTAQITITLLDINDNPPKF 442 HSP 5 Score: 121.709 bits (304), Expect = 1.202e-27 Identity = 100/332 (30.12%), Postives = 160/332 (48.19%), Query Frame = 2
Query: 1598 DNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSL-----FQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAP--ATIG----QLQYEDSDIGRNADVVFSKTWPNDDTVMIT---VNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRL---INPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDE 2542
+NPP+F + Q A V+E+ +GTV+ V+A D D G NG I YS+ +L F ID TGVIT + +DRE + + + A D G L + L I V DVNDN P FE ++ P +IG ++ D+D G N +V + + D + V+G + + K LDRE + L+V+ +D G N R ++ V I ++DVND P+ + +RE + V Q ++T + A D D +N ++ + I+ N + FS N G + + + L + IG + + V+ +D G P L ++
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPI----FERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQG-NPPRSATVTVKITLLDVNDCTPQFSKKVYSATIRE-------------DVPVNQ----LVTTVRATDCDQGSNGEVFFEIVSGNDM--NFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQ 322 HSP 6 Score: 101.293 bits (251), Expect = 1.874e-21 Identity = 153/656 (23.32%), Postives = 274/656 (41.77%), Query Frame = 2
Query: 578 AVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GL--YEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSS-GKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS--LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSV---RENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVN---GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKP-LSHHYIGHY 2491
++ I++LD+NDN P+FS++ ++E S + G+ + A D D P N + H C Q + L L+ + Y+ + +A D + V + V D N + P F +S VKE+ + + ++A D D+ S + Y A L FSV + VI + LD E+ Y+ V TD G+ +A+S + + + D ND P ++ +V E+ G + +V +D D + N ++I +S +S G + T D IRT DRE + + ++ +D +S + V + D D+PP F + Y V E+ P + ++ V A D + YS+ S +F I+ TG I +D E + Y+L + A S P + + + + D+NDN+P +L F ++ + P ++ D D+ +D + K + +T+N G L + K L + +K + +++ + D G R +S I + V +I EIDD + Y+ ++Q++ D +T ++LP + S +S T +L L K ++G++
Sbjct: 424 GTAQITITLLDINDNPPKFSQEEYHTSIAENS-RWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHDR---CFRINPQGLITLSCTLNYNTKHVYVFSV---SASDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKIS-YSIAT--LVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGK-NAQII-----------YSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQ----ASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRLTVRATLS---PFFTETTVMVYLKDINDNTP-VLEAFHMNINVQEGKVPPEARYKIPAYDPDV---SDKLTFKVMEGNAKEWVTLNATSGELSVNKKLIQASKPAN-IKIAVTD----GLRTASATGSIMMTSVTT---EMIQQSIQLEIDD----MEVLEFFNTAYEKLRESVSQIVKCKPDQVLMFDITSRVILP--VSSADYSKTRLTIWLVLRKKNEKEAFVGYF 1032 HSP 7 Score: 51.6026 bits (122), Expect = 2.208e-6 Identity = 87/415 (20.96%), Postives = 167/415 (40.24%), Query Frame = 2
Query: 560 SNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTD-GLYEAR-SXXXXXXXXXXXXSPQLIQNPSV-IEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRL-EFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLD--DGLNGKIHYSLEHDFSLFQIDSTTGVITV 1786
S+ L + V ++V D N + P+F ++ V E + G+ + ATD D NA+I Y +A F + + + LD E Y ++ A + + + V +++ D NDN P F + V+E+ + ++ A+D D + +N + + F++ +I LD E Y++ V TD G + SV ++ ++ +SP L + P + V E++ + V +D S G M P++ + + ++G + ++ D T++ + + +S + T+ V + D NDN P +V E K+ AYD D D L K+ ++ +++T+G ++V
Sbjct: 519 SDGMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDA-SLGTSVLTVLATDRDTG-SNAKISYSIATLVPEFSV---DETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRLTVRATLSPFF---------------TETTVMVYLKDINDNTPVLEAFHMNINVQEGKVPPEARYKIPAYDPDVSDKLTFKVMEGNAKEW--VTLNATSGELSV 911
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 224.172 bits (570), Expect = 9.064e-60 Identity = 220/799 (27.53%), Postives = 361/799 (45.18%), Query Frame = 2
Query: 272 GIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSS---GQG-HLELIVNLWSNVQLLA--VVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKS---FQLCLDQQRQ---PYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQ--------LIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSL-----SSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF---SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSP-CLLTPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFI 2563
G + + Y +QE +P + ++G++A D G+ H +YKL +D K+ +I I I+RE DC S G+ +LE V++ +Q + ++ RI V D+NDN PQF + V E + G+ + ATD D + N +Y L + F L + R P L +L +LD E + Y + I+A + + +++++ + + V D NDN P+F + V EN+P + Q+ A+D D + + L+Q A + + KL + + +I + LD E V D + +S + + D+ +P + + + + E+ G + V V+DKD+ + N + C P F L S+ NK+ Y ++T T D E+ + V ++ D S N L+S+ ++ VQ+ D NDN P F + + AE G IL V A D D G N ++ Y++ D LF+ID TG + + P+DRE KE Y+ + A D GS + + I V D NDN P +L+ + FSV EN+ P + +G + D D G NA V S V+ GT+ + DRE + + R++ D G R G V I V+D NDN P + T P+ S +S SP + + A D D N L + I N P Q+F + ++G ++L K ++ + G + + V V D G PP + ++++
Sbjct: 18 GPAKGSILYRVQEEQPPNTLIGSLAAD---HGLPDSGH---LYKLEVGAPYLRVDGKTG------DIFTTEIPIDRETLRDCRSLVKGKPCYLEFEVSVTDLLQNPSPRLIEGRIEVQDINDNTPQFPLSVLTISVPENT-IMGALFSIPLATDRD-SERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQ-AVDPVPKLLRIDRTTGIIYVKGPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGE-NAVVTCVVAGDVP---FQLRPASDSTSDNKR--KYFLQTTTPLDYERVKEYRVEIVAVD----SGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHLSVEPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVG-VTINVLDENDNDPVV------------TKPSNSSFRQLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGN--PYQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYV 776 HSP 2 Score: 64.6994 bits (156), Expect = 5.723e-10 Identity = 83/336 (24.70%), Postives = 133/336 (39.58%), Query Frame = 2
Query: 1637 HVAENGPIGTVILKVNAYDLDDGLNGKIH-YSLEHDFSLFQIDSTTG-VITVQGPVDRE-LKE----------HYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPATIGQLQYE-DSDIGRNADVVFSKTWPNDDTVMITVN---------GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
V E P T+I + A D GL H Y LE ++D TG + T + P+DRE L++ + + + D P + I V D+NDN+P L+ SV EN + + D D RN ++ T D + + L + LDRE KD + L ++ D G N +R S + + V D NDN P+ +P E+ + SP G+ + Q+ A D D N ++ Y + ++ + TTG + + PL I V +D G P + + +T++
Sbjct: 27 RVQEEQPPNTLIGSLAA---DHGLPDSGHLYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLRDCRSLVKGKPCYLEFEVSVTDLLQNPSPRLIEGRIEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGG-NPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSE-NSPV-------------GHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYVKGPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQ 344
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Match: pcdh1a (protocadherin-1 [Source:NCBI gene;Acc:101157079]) HSP 1 Score: 224.942 bits (572), Expect = 2.118e-59 Identity = 220/799 (27.53%), Postives = 361/799 (45.18%), Query Frame = 2
Query: 272 GIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSS---GQG-HLELIVNLWSNVQLLA--VVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKS---FQLCLDQQRQ---PYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQ--------LIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSL-----SSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDF---SLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSP-CLLTPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFI 2563
G + + Y +QE +P + ++G++A D G+ H +YKL +D K+ +I I I+RE DC S G+ +LE V++ +Q + ++ RI V D+NDN PQF + V E + G+ + ATD D + N +Y L + F L + R P L +L +LD E + Y + I+A + + +++++ + + V D NDN P+F + V EN+P + Q+ A+D D + + L+Q A + + KL + + +I + LD E V D + +S + + D+ +P + + + + E+ G + V V+DKD+ + N + C P F L S+ NK+ Y ++T T D E+ + V ++ D S N L+S+ ++ VQ+ D NDN P F + + AE G IL V A D D G N ++ Y++ D LF+ID TG + + P+DRE KE Y+ + A D GS + + I V D NDN P +L+ + FSV EN+ P + +G + D D G NA V S V+ GT+ + DRE + + R++ D G R G V I V+D NDN P + T P+ S +S SP + + A D D N L + I N P Q+F + ++G ++L K ++ + G + + V V D G PP + ++++
Sbjct: 95 GPAKGSILYRVQEEQPPNTLIGSLAAD---HGLPDSGH---LYKLEVGAPYLRVDGKTG------DIFTTEIPIDRETLRDCRSLVKGKPCYLEFEVSVTDLLQNPSPRLIEGRIEVQDINDNTPQFPLSVLTISVPENT-IMGALFSIPLATDRD-SERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGGNPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSENSPVGHSVLQVKADDSDMGPNGEIEYSLHQ-AVDPVPKLLRIDRTTGIIYVKGPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQNDNAPAVEIRGIGLVTHSEGIANISEDMPVGTAVALVQVSDKDEGE-NAVVTCVVAGDVP---FQLRPASDSTSDNKR--KYFLQTTTPLDYERVKEYRVEIVAVD----SGNPALSSTNSLKVQVTDVNDNSPVFSPTIFEVDFAEENQPGETILDVTATDADSGTNAELFYNIVGDSYIKGLFEIDPNTGEVKARTPLDREHKERYEFRVTAADKGSPVHKGTATVVIKVLDCNDNDPKFMLSGYSFSVLENMPPLSPVGMVTVLDMDKGENAHVHLSVEPDGGKFVVQNGTGTILSSISFDREKESSYTFRLKAVDGGEPPRSSYVG-VTINVLDENDNDPVV------------TKPSNSSFRQLSPVASPDSHVDVVEAEDLDSGPNADLVFSIAGGN--PYQLFRISPSSGEITLAKEMTRKHGGLHRLVVRVSDRGKPPRHATALVHIYV 853 HSP 2 Score: 64.6994 bits (156), Expect = 6.539e-10 Identity = 83/335 (24.78%), Postives = 133/335 (39.70%), Query Frame = 2
Query: 1640 VAENGPIGTVILKVNAYDLDDGLNGKIH-YSLEHDFSLFQIDSTTG-VITVQGPVDRE-LKE----------HYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCL-LTPFEFSVRENLAPATIGQLQYE-DSDIGRNADVVFSKTWPNDDTVMITVN---------GTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNK 2572
V E P T+I + A D GL H Y LE ++D TG + T + P+DRE L++ + + + D P + I V D+NDN+P L+ SV EN + + D D RN ++ T D + + L + LDRE KD + L ++ D G N +R S + + V D NDN P+ +P E+ + SP G+ + Q+ A D D N ++ Y + ++ + TTG + + PL I V +D G P + + +T++
Sbjct: 105 VQEEQPPNTLIGSLAA---DHGLPDSGHLYKLEVGAPYLRVDGKTGDIFTTEIPIDRETLRDCRSLVKGKPCYLEFEVSVTDLLQNPSPRLIEGRIEVQDINDNTPQFPLSVLTISVPENTIMGALFSIPLATDRDSERNGVADYALTAGPDAATLFGLQVADDRGGKLPQLIVLGNLDRELKDSYDLTIKAVDGG-NPQRYSQALLRVVVTDANDNSPKFEHPSYEAEVSE-NSPV-------------GHSVLQVKADDSDMGPNGEIEYSLHQAVDPVPKLLRIDRTTGIIYVKGPLDREEINSLSFYVVARDKGPQPKSSKTFVTIEVTDQ 421
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Match: pcdh9 (protocadherin 9 [Source:NCBI gene;Acc:101156238]) HSP 1 Score: 221.476 bits (563), Expect = 8.158e-59 Identity = 211/770 (27.40%), Postives = 350/770 (45.45%), Query Frame = 2
Query: 290 LKYLIQENEPIDRMVGTIATDIE--------GLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELS-SDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYE-ARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
L Y I+E + ++G I D+ G NL + L+ K + + T + ID E +C ++CS E+ V + N +++++I V D NDN P F I + E + S + +ATD D P N+ +Y L +F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F + V + EN+P + + QL A D D + + + + ++LF++ +I + LD E +K+ V +DG AR+ + + V D ND P + I +P + + E I + V+DK D+ NGK+IC E P F L + + + Y + T D E + + + ++ SD S N + + V++ D NDNPP F Q V EN + ++A D D G N +I Y L + S F +D TGV+T DRE ++ + + A D+G+ PL + + +TV D NDN+P F+F V ENL +T+G + DSD G NA + S N++ ++ +G + DRE + + VR D+G S+ +V I VIDVNDN P +I P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + IG + + V++ D G P
Sbjct: 26 LIYPIREELQENVLIGNIPKDLNISHTSAATGASANLVYR--LVSKAGDSPLVRVLGNTGEIFTTSNRIDREKLCPGSSFEDAECS-----FEIEVVVLPN-DYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFAIPSATDPDTGP-NSVHKYELINGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVIINVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDK-DTDINGKVICFIEKDVP---FHLKAVYDNQ---YLLETSALLDYEGTKEYNFKIVASDSGKPSLN----QTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVITVTDSDAGENAAISLSILNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAIDSG-RPPCSSAAKVTINVIDVNDNTPIVIYP-----------PSNTSFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVSGNN--KGLFRIDPVTGNITLEEKPAPTDIGLHRLVVNISDLGYP 760 HSP 2 Score: 122.094 bits (305), Expect = 1.246e-27 Identity = 105/370 (28.38%), Postives = 167/370 (45.14%), Query Frame = 2
Query: 1475 FDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSP-----CLLTPFEFSV---RENLAPATIGQLQYEDSDIGRNADVV--FSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQS--PGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
DRE+ + + DG + +S+ + V + D NDN P FR++Q H+ EN PIGT ++++ A D D G N +IHY S LF ++ST+G+ITVQ P+DRE +KL + A D S P ++V +N+T DVNDN P +++P +V ++ I + D D N V+ K P + L + LD E + ++ D+G Q++ V +R+ D NDN P P I ++V ++ +T L A D+D N ++ Y L PN + F + TG L+ + + V+ +D+G+PPL
Sbjct: 209 LDREQKDTYVMKIKVEDGGSPQK----SSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVIINVT--DVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDVPFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTA-LVRVRLEDENDNPPIFTQP----------------VIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQ-LGPN---ASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPL 551 HSP 3 Score: 88.5817 bits (218), Expect = 2.936e-17 Identity = 145/585 (24.79%), Postives = 232/585 (39.66%), Query Frame = 2
Query: 176 SYNYKLIFQQSGKMDILKTLFLFLTAVRCSETG--IKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLS-GPNCCFSIDQKSSVLTIAKNIDLESICINR--ELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVS-----EASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKF---RQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQ---GPVDRELKEHYKLHIHAVDSG 1852
+Y K+ + G T L +T ++ +E ++ I EN PI V + +G N E H ++S F+++ S ++T+ + +D E I++ L+SD SS +I+N V DVNDN P + I ++ + I L T +D D I + E F L Q L LD E Y KI A ++ V + ++D NDNPP F + + V EN + L A D DS +YQ N F + + V+ S D E R+ V D +A++ + V V DEND +P+ N V EN K +G + VTD D + SLS + + D I++ +FDRE+ S + + D S +S+ + + ++D NDN P + F V + G+V+ +V A D D G+N ++ Y++ ++ LF+ID TG IT++ P D L ++L ++ D G
Sbjct: 216 TYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVIIN----------------VTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICF--IEKDVPFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEI-VYQLGPNA--SFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVITVTDSDAGENAA--------------ISLSILNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAID----SGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDIGL---HRLVVNISDLG 758 HSP 4 Score: 68.1662 bits (165), Expect = 4.968e-11 Identity = 89/335 (26.57%), Postives = 152/335 (45.37%), Query Frame = 2
Query: 170 TVSYNYKLIFQQSGKMDILKTLFLFLTAVRCSETG-----IKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCC-FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN---DLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRF----NSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTV 1129
T YN+K++ SGK + +T L VR + + V++ + EN D + T++ E G N E ++Y+L GPN F +D+K+ VLT ++ D E +R L + + G L A V ++VLD NDN P+F+ + VSE K S + + T TD+D A ENA I + +++F L P+ ++ D E Q+ Y +RA ++ + V + V D NDN P +++ F ++ + P S++ ++ A D D+ + L++ + N L ++ V N T+
Sbjct: 431 TKEYNFKIVASDSGKPSLNQTA---LVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAE----IVYQL-GPNASFFDLDRKTGVLTASRVFDRED--QDRFLFTVTARDNG----------TPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKY-STVGVITVTDSD-AGENAAISLSILNDNENFIL------DPFSGVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSSIPG-SVVAEVFAVDSDTGMNAELKYTIVSGNNKGLFRIDPVTGNITL 736
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Match: pcdh9 (protocadherin 9 [Source:NCBI gene;Acc:101156238]) HSP 1 Score: 221.861 bits (564), Expect = 1.579e-58 Identity = 211/770 (27.40%), Postives = 350/770 (45.45%), Query Frame = 2
Query: 290 LKYLIQENEPIDRMVGTIATDIE--------GLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELS-SDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCL----DQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPD--STSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYE-ARSXXXXXXXXXXXXSPQL----IQNP--SVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLL-TPFEFSVRENLAP-ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSP 2527
L Y I+E + ++G I D+ G NL + L+ K + + T + ID E +C ++CS E+ V + N +++++I V D NDN P F I + E + S + +ATD D P N+ +Y L +F L + + ++ P L + +LD E + Y++KI+ + ++ + + + V D NDN P F + V + EN+P + + QL A D D + + + + ++LF++ +I + LD E +K+ V +DG AR+ + + V D ND P + I +P + + E I + V+DK D+ NGK+IC E P F L + + + Y + T D E + + + ++ SD S L + + V++ D NDNPP F Q V EN + ++A D D G N +I Y L + S F +D TGV+T DRE ++ + + A D+G+ PL + + +TV D NDN+P F+F V ENL +T+G + DSD G NA + S N++ ++ +G + DRE + + VR D+G S+ +V I VIDVNDN P +I P P+ + + + PG V+ ++ AVD D N +L Y I+ N +F + TG ++L++ + IG + + V++ D G P
Sbjct: 26 LIYPIREELQENVLIGNIPKDLNISHTSAATGASANLVYR--LVSKAGDSPLVRVLGNTGEIFTTSNRIDREKLCPGSSFEDAECS-----FEIEVVVLPN-DYFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT-LINSRFAIPSATDPDTGP-NSVHKYELINGQSAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVIINVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDK-DTDINGKVICFIEKDVP---FHLKAVYDNQ---YLLETSALLDYEGTKEYNFKIVASD----SGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQLGPNASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVITVTDSDAGENAAISLSILNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAIDSG-RPPCSSAAKVTINVIDVNDNTPIVIYP-----------PSNTSFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVSGNN--KGLFRIDPVTGNITLEEKPAPTDIGLHRLVVNISDLGYP 760 HSP 2 Score: 122.094 bits (305), Expect = 1.736e-27 Identity = 105/370 (28.38%), Postives = 167/370 (45.14%), Query Frame = 2
Query: 1475 FDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFS-----LFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSP-----CLLTPFEFSV---RENLAPATIGQLQYEDSDIGRNADVV--FSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQS--PGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPL 2533
DRE+ + + DG + +S+ + V + D NDN P FR++Q H+ EN PIGT ++++ A D D G N +IHY S LF ++ST+G+ITVQ P+DRE +KL + A D S P ++V +N+T DVNDN P +++P +V ++ I + D D N V+ K P + L + LD E + ++ D+G Q++ V +R+ D NDN P P I ++V ++ +T L A D+D N ++ Y L PN + F + TG L+ + + V+ +D+G+PPL
Sbjct: 209 LDREQKDTYVMKIKVEDG----GSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVIINVT--DVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDVPFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTA-LVRVRLEDENDNPPIFTQP----------------VIELAVMENNKRDLFLTTLSATDEDSGKNAEIVYQ-LGPN---ASFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPL 551 HSP 3 Score: 88.9669 bits (219), Expect = 2.237e-17 Identity = 139/561 (24.78%), Postives = 222/561 (39.57%), Query Frame = 2
Query: 176 SYNYKLIFQQSGKMDILKTLFLFLTAVRCSETG--IKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLS-GPNCCFSIDQKSSVLTIAKNIDLESICINR--ELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVS-----EASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDG---LYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYD-----IRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKF---RQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQ 1789
+Y K+ + G T L +T ++ +E ++ I EN PI V + +G N E H ++S F+++ S ++T+ + +D E I++ L+SD SS +I+N V DVNDN P + I ++ + I L T +D D I + E F L Q L LD E Y KI A ++ V + ++D NDNPP F + + V EN + L A D DS +YQ N F + + V+ S D E R+ V D +A++ + V V DEND +P+ N V EN K +G + VTD D + SLS + + D I++ +FDRE+ S + + D S +S+ + + ++D NDN P + F V + G+V+ +V A D D G+N ++ Y++ ++ LF+ID TG IT++
Sbjct: 216 TYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNKPVFRENQIEVHIPENSPIGTSVVQLQATDADIGPNAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVIIN----------------VTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICF--IEKDVPFHLKAVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAEI-VYQLGPNA--SFFDLDRKTGVLTASRVFDREDQDRFLFTVTARDNGTPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVITVTDSDAGENAA--------------ISLSILNDNENFILDPFSGVIKSNVSFDREQQSSYTFDVRAID----SGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSSIPGSVVAEVFAVDSDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLE 737 HSP 4 Score: 68.5514 bits (166), Expect = 3.742e-11 Identity = 89/335 (26.57%), Postives = 152/335 (45.37%), Query Frame = 2
Query: 170 TVSYNYKLIFQQSGKMDILKTLFLFLTAVRCSETG-----IKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCC-FSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLN---DLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRF----NSSLFSVLVKENTPARSMIFQLIANDPDS--TSVLRFDLYQTANNELRKLFSVLQNGTV 1129
T YN+K++ SGK + +T L VR + + V++ + EN D + T++ E G N E ++Y+L GPN F +D+K+ VLT ++ D E +R L + + G L A V ++VLD NDN P+F+ + VSE K S + + T TD+D A ENA I + +++F L P+ ++ D E Q+ Y +RA ++ + V + V D NDN P +++ F ++ + P S++ ++ A D D+ + L++ + N L ++ V N T+
Sbjct: 431 TKEYNFKIVASDSGKPSLNQTA---LVRVRLEDENDNPPIFTQPVIELAVMENNKRDLFLTTLSATDEDSGKNAE----IVYQL-GPNASFFDLDRKTGVLTASRVFDRED--QDRFLFTVTARDNG----------TPPLQAQAAVIVTVLDENDNNPKFTHNHFQFFVSENLPKY-STVGVITVTDSD-AGENAAISLSILNDNENFIL------DPFSGVIKSNVSFDREQQSSYTFDVRAIDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSSIPG-SVVAEVFAVDSDTGMNAELKYTIVSGNNKGLFRIDPVTGNITL 736
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 220.705 bits (561), Expect = 1.921e-58 Identity = 210/807 (26.02%), Postives = 358/807 (44.36%), Query Frame = 2
Query: 236 FLFLTAVRCSETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSS----GQGHLELIVNLWSNVQLLAV----VRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQ------QRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSV--LRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXX---SPQL--------IQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSL--EHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSP-CLLTPFEFSVRENLAPAT-IGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFI 2563
+ LT V G Y + E +P + ++G++A D LG+ H +YKL + +D K+ + + I I+RE SDC + + LE V++ V+ + + + I VLD+NDN PQFS + + E +H G+ + A D D N EY L+ + QL Q ++ P + ++ +LD E + Y + IR + + + + + V D NDN P+F + + + EN+P + Q+ AND D+ + + + L+Q A++ +++L + ++ +I + +D E K V D ++S + D+ +P + I V + E+ G + V V+D+D+ + N + C P S N + Y ++T T D E+ + ++ D S N L+S+ ++ VQ+ D NDN P F + + AE+ G ++ V A D D G+N ++ YS+ SLF+I+S TG I V+ +DRE E Y+ + A D G + + I V+D NDN P +L+ + FSV EN+ P +G + D+D G N+ V N ++ GT+ + DRE + + R++ D G R G V I V+D NDN P + T PA S + P + + A D D N +L Y I N P +F + +G + L + + + G + + V V D G PP + ++++
Sbjct: 23 LVLLTIVLMVPCGAVPSNNIYKLSEEQPPNTLIGSLAAD---LGLPDSGH---LYKLEVGSPYLRVDSKTGEIYTTE------IPIDRETLSDCRNLFEDDKCFLEFEVSITDMVKGIGLGPRLIEGIIEVLDINDNTPQFSSPILTLSIPENTH-TGTLFSIPVAVDRDSG-SNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQ-ASDTVQRLLRIDRSTGIIYVKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGE-NAVVTCVVAGDVPFQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVD----SGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLFVEPDNGKFIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRSSYVG-VTINVLDENDNAPYV------------TKPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGN--PHGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHVYV 794 HSP 2 Score: 90.8929 bits (224), Expect = 6.029e-18 Identity = 113/465 (24.30%), Postives = 202/465 (43.44%), Query Frame = 2
Query: 584 VRVRISVLDVNDNIPQFS--------KQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQL------CLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXS---PQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEP-RLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQ--SQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLE--HDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDN 1912
+V IS+ D NDN P Q ++SE G+ + L +D D ENA + +A FQL D++R+ +L LD E Y I+I A ++ + + ++ + V D NDN P F+ +L V E+ + ++A D DS +Y + LF + N I + + LD E +RY+ V D +++ ++V + D + P+ + + V EN +G V V+D D + + + EP +F + +G T I + +FDREK S + L D + +S + + +LD NDN P + + + H+ + P T + V A D+D G+N +++Y++ + LFQI +G I + + K ++L + D G P +++ +++ V++ +N
Sbjct: 354 AQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISE-DMPIGTPVALVQVSDRDEG-ENAVVTCVVA-GDVPFQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAEL-VYSIIESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLF----VEPDNGKFIIQNG------TGTILSSISFDREKESTYTFRLKAVDAGDPPR----SSYVGVTINVLDENDNAPYVTKPANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNPHGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHVYVNETTNN 800
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Match: SMESG000059102.1 (SMESG000059102.1) HSP 1 Score: 2184.07 bits (5658), Expect = 0.000e+0 Identity = 1091/1093 (99.82%), Postives = 1091/1093 (99.82%), Query Frame = 2
Query: 143 MRTIEYTFVTVSYNYKLIFQQSGKMDILKTLFLFLTAVRCSETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGGSWVDKNXXXXXXXXXXXXXXXXAMLVTAIICMLKPCYQRNNNRYDKNWIKKISSGRTESMKNAGTIDSNSGALQENLLVNGNSDISSSFLNSCIETSIDNKPFGNIETAIYSDDHLGYISNSSVPRCHGNRMLTGRNTISRLDYGVCSQCPIMSNYGSPGYATFGHYIDTSNDEEIKEDFQSDSGRGASEDDTSRTNGIRLKVVGQVSSFKENSAEKENANIPMVTLSGRIDSGNNSISQKISPTNNYLQSGVLCDEINQLFFHNLIKP 3421
MRTIEYTFVTVSYNYKLIFQQSGKMDILKTLFLFLTAVRCSETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSVLEVLVEDENDESPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILD NDNPPKFRQSQYFAHVAEN PIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGGSWVDKNSLLVVIILSCISLSFIAMLVTAIICMLKPCYQRNNNRYDKNWIKKISSGRTESMKNAGTIDSNSGALQENLLVNGNSDISSSFLNSCIETSIDNKPFGNIETAIYSDDHLGYISNSSVPRCHGNRMLTGRNTISRLDYGVCSQCPIMSNYGSPGYATFGHYIDTSNDEEIKEDFQSDSGRGASEDDTSRTNGIRLKVVGQVSSFKENSAEKENANIPMVTLSGRIDSGNNSISQKISPTNNYLQSGVLCDEINQLFFHNLIKP
Sbjct: 1 MRTIEYTFVTVSYNYKLIFQQSGKMDILKTLFLFLTAVRCSETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSVLEVLVEDENDESPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDLNDNPPKFRQSQYFAHVAENSPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGGSWVDKNSLLVVIILSCISLSFIAMLVTAIICMLKPCYQRNNNRYDKNWIKKISSGRTESMKNAGTIDSNSGALQENLLVNGNSDISSSFLNSCIETSIDNKPFGNIETAIYSDDHLGYISNSSVPRCHGNRMLTGRNTISRLDYGVCSQCPIMSNYGSPGYATFGHYIDTSNDEEIKEDFQSDSGRGASEDDTSRTNGIRLKVVGQVSSFKENSAEKENANIPMVTLSGRIDSGNNSISQKISPTNNYLQSGVLCDEINQLFFHNLIKP 1093
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Match: SMESG000059102.1 (SMESG000059102.1) HSP 1 Score: 2135.15 bits (5531), Expect = 0.000e+0 Identity = 1067/1069 (99.81%), Postives = 1067/1069 (99.81%), Query Frame = 2
Query: 215 MDILKTLFLFLTAVRCSETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGGSWVDKNXXXXXXXXXXXXXXXXAMLVTAIICMLKPCYQRNNNRYDKNWIKKISSGRTESMKNAGTIDSNSGALQENLLVNGNSDISSSFLNSCIETSIDNKPFGNIETAIYSDDHLGYISNSSVPRCHGNRMLTGRNTISRLDYGVCSQCPIMSNYGSPGYATFGHYIDTSNDEEIKEDFQSDSGRGASEDDTSRTNGIRLKVVGQVSSFKENSAEKENANIPMVTLSGRIDSGNNSISQKISPTNNYLQSGVLCDEINQLFFHNLIKP 3421
MDILKTLFLFLTAVRCSETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSVLEVLVEDENDESPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILD NDNPPKFRQSQYFAHVAEN PIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGGSWVDKNSLLVVIILSCISLSFIAMLVTAIICMLKPCYQRNNNRYDKNWIKKISSGRTESMKNAGTIDSNSGALQENLLVNGNSDISSSFLNSCIETSIDNKPFGNIETAIYSDDHLGYISNSSVPRCHGNRMLTGRNTISRLDYGVCSQCPIMSNYGSPGYATFGHYIDTSNDEEIKEDFQSDSGRGASEDDTSRTNGIRLKVVGQVSSFKENSAEKENANIPMVTLSGRIDSGNNSISQKISPTNNYLQSGVLCDEINQLFFHNLIKP
Sbjct: 1 MDILKTLFLFLTAVRCSETGIKECVLKYLIQENEPIDRMVGTIATDIEGLGINLEFHGSLIYKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSVLEVLVEDENDESPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPRLEFSLSSGKNKKILTYDIRTKTAFDREKSSQISVVLICSDGWNTSANIHLTSSFTINVQILDLNDNPPKFRQSQYFAHVAENSPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAPATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISISVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGGSWVDKNSLLVVIILSCISLSFIAMLVTAIICMLKPCYQRNNNRYDKNWIKKISSGRTESMKNAGTIDSNSGALQENLLVNGNSDISSSFLNSCIETSIDNKPFGNIETAIYSDDHLGYISNSSVPRCHGNRMLTGRNTISRLDYGVCSQCPIMSNYGSPGYATFGHYIDTSNDEEIKEDFQSDSGRGASEDDTSRTNGIRLKVVGQVSSFKENSAEKENANIPMVTLSGRIDSGNNSISQKISPTNNYLQSGVLCDEINQLFFHNLIKP 1069
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Match: SMESG000016762.1 (SMESG000016762.1) HSP 1 Score: 500.745 bits (1288), Expect = 3.460e-157 Identity = 395/1172 (33.70%), Postives = 598/1172 (51.02%), Query Frame = 2
Query: 218 DILKTLFLFLTAVRCSETGIKECVLKYLIQENEPIDRMVGTIATDI----EGLGINLEFHGSLI-YKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPR-------LEFSLSSGKNKKILTYDIRTKTAFDRE-------KSSQISVVLICSDGWN-TSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAP---ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISI--SVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGG-SWVDKNXXXXXXXXXXXXXXXXAMLVTAIICMLKPCYQRNN------------NRYDKNWIKKISSGRTES----MKNAGTIDSNSGALQENLLVNGNSDISSSFLNSCI----ETSIDN---KPFGNIETAIYSDDH--------------LGYISNSSVPRCHGNRMLTGRNTISRLDYG------VCSQCPIMSNYGSPGYATFGH----YIDTSNDEEI--KEDFQSDSGRGASEDDTSRTNGIRLKVVGQVSSFKENSAEKENA-NIPMVTLSGRIDSG-NNSISQKISPT------------------NNYLQS-----------GVLCDEINQLFFHNLI 3415
+IL FL + E GI+ L Y IQEN ++ ++GT++ D+ + + F+ L+ Y L + F + K+ L + ID++ IC+ + C S LEL VNLW N +L+AV+ V ++VLDVNDN P F +I V+E +HK G IFL A D DI+ + ++I YGL+ + F+L + +PYL LL D D E HY ++AWN + L+V + V DFNDN P F SSL +++ ENTP S IFQL A D D T+ + + + +A ELR +F V NG V L LDYE Y +PV V+DG+Y L++ +E+ NDE P+ + NPS ++V+E + GL IGQV + D DD NGK+IC EP+ LEF + K+ + Y+I+TK ++DRE K + I +LIC+DGW +S + LTS+ I+V + D NDN P+F Y + V EN ++V+A+D D G N I +SL D F+ID+ +G I+ + DRE K +Y +++ D G PL+S+ +NIT+ DVNDN+P L + ++ EN + L YED D N V FSK WP D ++T NG+++ DRET+DR+CL VRL+D+G + + S+G VCI+++D NDN+P + +P+GL D+ P ++ I I S+Y++PGY + + A DDDD N + + + P +P ++F TG L L++ LS IG + ++++V+D G P L ++ + I ++P + + GG W+ +LLVVIILS +S+ I +L+TAI+C+LKPC N NRY N KI+ +S MK +EN+ + + + SS+ N+ + + +DN P G+ I D H L + NS+ C ++ + + + S P+ S P ++FGH ++ N ++ ++ QSDSGRG S+DD + + V+ Q N N P T S I S N + Q SPT ++ L + G LC+EIN LFF LI
Sbjct: 6 NILYVSFLIIQICNFCE-GIERFSLTYTIQENTAVETLIGTVSVDLYDRFKTNNLPKIFNNKLVTYSLGTTSTYFHLSAKNGKLFVKSIIDVDEICV-KSSKKICKSDYASLELNVNLWFNEKLIAVINVVVNVLDVNDNQPNFPTTKITIPVNEINHKTGRKIFLPQAIDKDISEKFSKIFYGLSTKNSDFELQVGHPHKPYLKLLKDFDCERLDHYTFLLQAWNHDMSDNRAHLSVTIEVLDFNDNEPNFTSSLLKLVISENTPLNSKIFQLTATDRDKTAQITYYMDSSAPQELRNIFEVKPNGGVWLKDQKLDYETTSSYSIPVLVSDGIYSNTGELKISLENVNDEPPKFLLNPSNLKVVEKNTPGLSIGQVTIIDADDDSVNGKIIC----NEPKSLDGYQDLEFHKTLTKDFQENVYEIKTKRSYDREMLTTSHNKEAYIKAILICNDGWGMSSTSPRLTSTLKISVFVEDLNDNAPQFDLKVYHSSVPENSGPEAKCVQVHAHDKDSGDNAAITFSL-LDNEDFKIDAISGWISAKHTFDRETKNYYLINVVVRDKGDPPLSSTALVNITIKDVNDNAPELKHTMDLNLSENQKVNKLELLAVLSYEDKDEDENGRVTFSKIWPYDSNFLLTSNGSIFYNSVFDRETQDRYCLSVRLQDHGYDKQHYSTGTVCIKILDQNDNEPIIKSPKGLLPADNIFGPTSAPFIPIILSLYETPGYKLVTIEAKDDDDGDNGTVIFSLDTPLGMP-KLFKITPNTGDLLLNQTLSVVDIGMHRVRITVQDLGKPSLFTSQVAVIKIEDRPPSSEILTEPGLGGIYWIGGKNLLVVIILSTLSVILIVILITAILCLLKPCRDIENGNGNTLYSYEGTNRYFSNCANKINVDYFQSSILRMKKFC-----ENPDEENIGYSVDRTLLSSYTNNDMINQPQILLDNYIYHPNGDFPEEICVDQHYQQWPVFQASDESKLSQLQNSNFNYCPAEGAISNNLQFFKFNLNNSNENTLNSFIPMSSYNTGPKASSFGHPTPLFLSPMNLSKVLQHDEQQSDSGRGNSDDDIVNLSNNQSSVIYQKIYSPLNLTSISNTYTFPKHTKSCHIASTCNQPLHQLGSPTPPTATRNHQPFTETSGSSDHNLSTDPEEKSRSGDLGHLCEEINDLFFKKLI 1164
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Match: SMESG000016762.1 (SMESG000016762.1) HSP 1 Score: 502.671 bits (1293), Expect = 1.140e-155 Identity = 378/1107 (34.15%), Postives = 582/1107 (52.57%), Query Frame = 2
Query: 197 FQQSGKMDILKTLFLFLTAVRCSETGIKECVLKYLIQENEPIDRMVGTIATDI----EGLGINLEFHGSLI-YKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPR-------LEFSLSSGKNKKILTYDIRTKTAFDRE-------KSSQISVVLICSDGWN-TSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAP---ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISI--SVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGG-SWVDKNXXXXXXXXXXXXXXXXAMLVTAIICMLKPCYQRNN------------NRYDKNWIKKISSGRTES----MKNAGTIDSNSGALQENLLVNGNSDISSSFLNSCI----ETSIDN---KPFGNIETAIYSDDH--------------LGYISNSSVPRCHGNRMLTGRNTISRLDYG------VCSQCPIMSNYGSPGYATFGH----YIDTSNDEEI--KEDFQSDSGRGASEDDTSRTNGIRLKVVGQVSSFKENSAEKENANIPMVT 3292
F GK +IL FL + E GI+ L Y IQEN ++ ++GT++ D+ + + F+ L+ Y L + F + K+ L + ID++ IC+ + C S LEL VNLW N +L+AV+ V ++VLDVNDN P F +I V+E +HK G IFL A D DI+ + ++I YGL+ + F+L + +PYL LL D D E HY ++AWN + L+V + V DFNDN P F SSL +++ ENTP S IFQL A D D T+ + + + +A ELR +F V NG V L LDYE Y +PV V+DG+Y L++ +E+ NDE P+ + NPS ++V+E + GL IGQV + D DD NGK+IC EP+ LEF + K+ + Y+I+TK ++DRE K + I +LIC+DGW +S + LTS+ I+V + D NDN P+F Y + V EN ++V+A+D D G N I +SL D F+ID+ +G I+ + DRE K +Y +++ D G PL+S+ +NIT+ DVNDN+P L + ++ EN + L YED D N V FSK WP D ++T NG+++ DRET+DR+CL VRL+D+G + + S+G VCI+++D NDN+P + +P+GL D+ P ++ I I S+Y++PGY + + A DDDD N + + + P +P ++F TG L L++ LS IG + ++++V+D G P L ++ + I ++P + + GG W+ +LLVVIILS +S+ I +L+TAI+C+LKPC N NRY N KI+ +S MK +EN+ + + + SS+ N+ + + +DN P G+ I D H L + NS+ C ++ + + + S P+ S P ++FGH ++ N ++ ++ QSDSGRG S+DD + + V+ Q S+ K +++ + I + T
Sbjct: 9 FMSIGK-NILYVSFLIIQICNFCE-GIERFSLTYTIQENTAVETLIGTVSVDLYDRFKTNNLPKIFNNKLVTYSLGTTSTYFHLSAKNGKLFVKSIIDVDEICV-KSSKKICKSDYASLELNVNLWFNEKLIAVINVVVNVLDVNDNQPNFPTTKITIPVNEINHKTGRKIFLPQAIDKDISEKFSKIFYGLSTKNSDFELQVGHPHKPYLKLLKDFDCERLDHYTFLLQAWNHDMSDNRAHLSVTIEVLDFNDNEPNFTSSLLKLVISENTPLNSKIFQLTATDRDKTAQITYYMDSSAPQELRNIFEVKPNGGVWLKDQKLDYETTSSYSIPVLVSDGIYSNTGELKISLENVNDEPPKFLLNPSNLKVVEKNTPGLSIGQVTIIDADDDSVNGKIIC----NEPKSLDGYQDLEFHKTLTKDFQENVYEIKTKRSYDREMLTTSHNKEAYIKAILICNDGWGMSSTSPRLTSTLKISVFVEDLNDNAPQFDLKVYHSSVPENSGPEAKCVQVHAHDKDSGDNAAITFSL-LDNEDFKIDAISGWISAKHTFDRETKNYYLINVVVRDKGDPPLSSTALVNITIKDVNDNAPELKHTMDLNLSENQKVNKLELLAVLSYEDKDEDENGRVTFSKIWPYDSNFLLTSNGSIFYNSVFDRETQDRYCLSVRLQDHGYDKQHYSTGTVCIKILDQNDNEPIIKSPKGLLPADNIFGPTSAPFIPIILSLYETPGYKLVTIEAKDDDDGDNGTVIFSLDTPLGMP-KLFKITPNTGDLLLNQTLSVVDIGMHRVRITVQDLGKPSLFTSQVAVIKIEDRPPSSEILTEPGLGGIYWIGGKNLLVVIILSTLSVILIVILITAILCLLKPCRDIENGNGNTLYSYEGTNRYFSNCANKINVDYFQSSILRMKKFC-----ENPDEENIGYSVDRTLLSSYTNNDMINQPQILLDNYIYHPNGDFPEEICVDQHYQQWPVFQASDESKLSQLQNSNFNYCPAEGAISNNLQFFKFNLNNSNENTLNSFIPMSSYNTGPKASSFGHPTPLFLSPMNLSKVLQHDEQQSDSGRGNSDDDIVNLSNNQSSVIYQKSNIKTRNSQTDYQTIQLST 1101
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Match: SMESG000016762.1 (SMESG000016762.1) HSP 1 Score: 501.13 bits (1289), Expect = 3.933e-155 Identity = 375/1100 (34.09%), Postives = 579/1100 (52.64%), Query Frame = 2
Query: 218 DILKTLFLFLTAVRCSETGIKECVLKYLIQENEPIDRMVGTIATDI----EGLGINLEFHGSLI-YKLSGPNCCFSIDQKSSVLTIAKNIDLESICINRELSSDCSSGQGHLELIVNLWSNVQLLAVVRVRISVLDVNDNIPQFSKQRIERHVSEASHKAGSHIFLETATDTDIAPENAQIEYGLAEHHKSFQLCLDQQRQPYLFLLNDLDAENQTHYLIKIRAWNAQDNKQWNELNVDLYVDDFNDNPPRFNSSLFSVLVKENTPARSMIFQLIANDPDSTSVLRFDLYQTANNELRKLFSVLQNGTVILISSWLDYERHQRYKVPVFVTDGLYEARSXXXXXXXXXXXXSPQLIQNPSVIEVMENSGKGLVIGQVIVTDKDDSQTNGKMICEHETTEPR-------LEFSLSSGKNKKILTYDIRTKTAFDRE-------KSSQISVVLICSDGWN-TSANIHLTSSFTINVQILDFNDNPPKFRQSQYFAHVAENGPIGTVILKVNAYDLDDGLNGKIHYSLEHDFSLFQIDSTTGVITVQGPVDRELKEHYKLHIHAVDSGSIPLNSSVGLNITVDDVNDNSPCLLTPFEFSVRENLAP---ATIGQLQYEDSDIGRNADVVFSKTWPNDDTVMITVNGTLYITKPLDRETKDRHCLRVRLRDNGLNGRRQSSGEVCIRVIDVNDNKPRLINPRGLREIDDATSPAASQSISI--SVYQSPGYVITQLIAVDDDDATNTKLTYHILLPNTLPSQIFSFNSTTGYLSLDKPLSHHYIGHYPIKVSVKDSGSPPLIDEKMFYLFITNKPAKYDDKLQSNNGG-SWVDKNXXXXXXXXXXXXXXXXAMLVTAIICMLKPCYQRNN------------NRYDKNWIKKISSGRTES----MKNAGTIDSNSGALQENLLVNGNSDISSSFLNSCI----ETSIDN---KPFGNIETAIYSDDH--------------LGYISNSSVPRCHGNRMLTGRNTISRLDYG------VCSQCPIMSNYGSPGYATFGH----YIDTSNDEEI--KEDFQSDSGRGASEDDTSRTNGIRLKVVGQVSSFKENSAEKENANIPMVT 3292
+IL FL + E GI+ L Y IQEN ++ ++GT++ D+ + + F+ L+ Y L + F + K+ L + ID++ IC+ + C S LEL VNLW N +L+AV+ V ++VLDVNDN P F +I V+E +HK G IFL A D DI+ + ++I YGL+ + F+L + +PYL LL D D E HY ++AWN + L+V + V DFNDN P F SSL +++ ENTP S IFQL A D D T+ + + + +A ELR +F V NG V L LDYE Y +PV V+DG+Y L++ +E+ NDE P+ + NPS ++V+E + GL IGQV + D DD NGK+IC EP+ LEF + K+ + Y+I+TK ++DRE K + I +LIC+DGW +S + LTS+ I+V + D NDN P+F Y + V EN ++V+A+D D G N I +SL D F+ID+ +G I+ + DRE K +Y +++ D G PL+S+ +NIT+ DVNDN+P L + ++ EN + L YED D N V FSK WP D ++T NG+++ DRET+DR+CL VRL+D+G + + S+G VCI+++D NDN+P + +P+GL D+ P ++ I I S+Y++PGY + + A DDDD N + + + P +P ++F TG L L++ LS IG + ++++V+D G P L ++ + I ++P + + GG W+ +LLVVIILS +S+ I +L+TAI+C+LKPC N NRY N KI+ +S MK +EN+ + + + SS+ N+ + + +DN P G+ I D H L + NS+ C ++ + + + S P+ S P ++FGH ++ N ++ ++ QSDSGRG S+DD + + V+ Q S+ K +++ + I + T
Sbjct: 6 NILYVSFLIIQICNFCE-GIERFSLTYTIQENTAVETLIGTVSVDLYDRFKTNNLPKIFNNKLVTYSLGTTSTYFHLSAKNGKLFVKSIIDVDEICV-KSSKKICKSDYASLELNVNLWFNEKLIAVINVVVNVLDVNDNQPNFPTTKITIPVNEINHKTGRKIFLPQAIDKDISEKFSKIFYGLSTKNSDFELQVGHPHKPYLKLLKDFDCERLDHYTFLLQAWNHDMSDNRAHLSVTIEVLDFNDNEPNFTSSLLKLVISENTPLNSKIFQLTATDRDKTAQITYYMDSSAPQELRNIFEVKPNGGVWLKDQKLDYETTSSYSIPVLVSDGIYSNTGELKISLENVNDEPPKFLLNPSNLKVVEKNTPGLSIGQVTIIDADDDSVNGKIIC----NEPKSLDGYQDLEFHKTLTKDFQENVYEIKTKRSYDREMLTTSHNKEAYIKAILICNDGWGMSSTSPRLTSTLKISVFVEDLNDNAPQFDLKVYHSSVPENSGPEAKCVQVHAHDKDSGDNAAITFSL-LDNEDFKIDAISGWISAKHTFDRETKNYYLINVVVRDKGDPPLSSTALVNITIKDVNDNAPELKHTMDLNLSENQKVNKLELLAVLSYEDKDEDENGRVTFSKIWPYDSNFLLTSNGSIFYNSVFDRETQDRYCLSVRLQDHGYDKQHYSTGTVCIKILDQNDNEPIIKSPKGLLPADNIFGPTSAPFIPIILSLYETPGYKLVTIEAKDDDDGDNGTVIFSLDTPLGMP-KLFKITPNTGDLLLNQTLSVVDIGMHRVRITVQDLGKPSLFTSQVAVIKIEDRPPSSEILTEPGLGGIYWIGGKNLLVVIILSTLSVILIVILITAILCLLKPCRDIENGNGNTLYSYEGTNRYFSNCANKINVDYFQSSILRMKKFC-----ENPDEENIGYSVDRTLLSSYTNNDMINQPQILLDNYIYHPNGDFPEEICVDQHYQQWPVFQASDESKLSQLQNSNFNYCPAEGAISNNLQFFKFNLNNSNENTLNSFIPMSSYNTGPKASSFGHPTPLFLSPMNLSKVLQHDEQQSDSGRGNSDDDIVNLSNNQSSVIYQKSNIKTRNSQTDYQTIQLST 1092 The following BLAST results are available for this feature:
BLAST of Protocadherin alpha-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin alpha-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin alpha-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin alpha-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30026029 ID=SMED30026029|Name=Protocadherin alpha-2|organism=Schmidtea mediterranea sexual|type=transcript|length=3576bpback to top protein sequence of SMED30026029-orf-1 >SMED30026029-orf-1 ID=SMED30026029-orf-1|Name=SMED30026029-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1094bp MRTIEYTFVTVSYNYKLIFQQSGKMDILKTLFLFLTAVRCSETGIKECVLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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